LOCUS       DAFTHM010000001        95872 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFTHM010000001 DAFTHM010000000
VERSION     DAFTHM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 95872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 95872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..95872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.001"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..529
                     /locus_tag="L7C88_000001"
     CDS             <1..529
                     /locus_tag="L7C88_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBP9556869.1"
                     /translation="YFIDLDLLQLINSVKRMYSGDDNGVDLYKFVTKHIFVNLNIDEK
                     NYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGITLTTAHKVKGNEYDTV
                     IAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNLFLFSEVGYFTSKGDLL
                     YPTQLLDKIEFDYNI"
     gene            729..1043
                     /locus_tag="L7C88_000002"
     CDS             729..1043
                     /locus_tag="L7C88_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBP9556870.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            1064..1441
                     /locus_tag="L7C88_000003"
     CDS             1064..1441
                     /locus_tag="L7C88_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBP9556871.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            1451..2224
                     /locus_tag="L7C88_000004"
     CDS             1451..2224
                     /locus_tag="L7C88_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9556872.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            2246..3649
                     /locus_tag="L7C88_000005"
     CDS             2246..3649
                     /locus_tag="L7C88_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBP9556873.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            3831..5015
                     /locus_tag="L7C88_000006"
     CDS             3831..5015
                     /locus_tag="L7C88_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBP9556874.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            5012..5302
                     /locus_tag="L7C88_000007"
     CDS             5012..5302
                     /locus_tag="L7C88_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9556875.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            5299..5520
                     /locus_tag="L7C88_000008"
     CDS             5299..5520
                     /locus_tag="L7C88_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9556876.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            5562..6341
                     /locus_tag="L7C88_000009"
     CDS             5562..6341
                     /locus_tag="L7C88_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBP9556877.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            6408..6902
                     /locus_tag="L7C88_000010"
     CDS             6408..6902
                     /locus_tag="L7C88_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBP9556878.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            6958..7596
                     /locus_tag="L7C88_000011"
     CDS             6958..7596
                     /locus_tag="L7C88_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9556879.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            7668..8063
                     /locus_tag="L7C88_000012"
     CDS             7668..8063
                     /locus_tag="L7C88_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBP9556880.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            8047..10500
                     /locus_tag="L7C88_000013"
     CDS             8047..10500
                     /locus_tag="L7C88_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBP9556881.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            10497..12524
                     /locus_tag="L7C88_000014"
     CDS             10497..12524
                     /locus_tag="L7C88_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9556882.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            12521..13543
                     /locus_tag="L7C88_000015"
     CDS             12521..13543
                     /locus_tag="L7C88_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBP9556883.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            13560..14489
                     /locus_tag="L7C88_000016"
     CDS             13560..14489
                     /locus_tag="L7C88_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBP9556884.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            14734..14850
                     /locus_tag="L7C88_000017"
     CDS             14734..14850
                     /locus_tag="L7C88_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBP9556885.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            14866..15669
                     /locus_tag="L7C88_000018"
     CDS             14866..15669
                     /locus_tag="L7C88_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBP9556886.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            15904..16140
                     /locus_tag="L7C88_000019"
     CDS             15904..16140
                     /locus_tag="L7C88_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9556887.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            16147..18099
                     /locus_tag="L7C88_000020"
     CDS             16147..18099
                     /locus_tag="L7C88_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBP9556888.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(18171..18668)
                     /gene="dfrG"
                     /locus_tag="L7C88_000021"
     CDS             complement(18171..18668)
                     /gene="dfrG"
                     /locus_tag="L7C88_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBP9556889.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            19030..20070
                     /locus_tag="L7C88_000022"
     CDS             19030..20070
                     /locus_tag="L7C88_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBP9556890.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            20168..20356
                     /locus_tag="L7C88_000023"
     CDS             20168..20356
                     /locus_tag="L7C88_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBP9556891.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(20414..20767)
                     /locus_tag="L7C88_000024"
     CDS             complement(20414..20767)
                     /locus_tag="L7C88_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9556892.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            21298..21720
                     /locus_tag="L7C88_000025"
     CDS             21298..21720
                     /locus_tag="L7C88_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBP9556893.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            21717..21947
                     /locus_tag="L7C88_000026"
     CDS             21717..21947
                     /locus_tag="L7C88_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9556894.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            22445..22645
                     /locus_tag="L7C88_000027"
     CDS             22445..22645
                     /locus_tag="L7C88_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBP9556895.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            22672..23865
                     /locus_tag="L7C88_000028"
     CDS             22672..23865
                     /locus_tag="L7C88_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBP9556896.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(23933..25498)
                     /gene="guaA"
                     /locus_tag="L7C88_000029"
     CDS             complement(23933..25498)
                     /gene="guaA"
                     /locus_tag="L7C88_000029"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBP9556897.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(25557..26480)
                     /locus_tag="L7C88_000030"
     CDS             complement(25557..26480)
                     /locus_tag="L7C88_000030"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBP9556898.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            26676..27281
                     /locus_tag="L7C88_000031"
     CDS             26676..27281
                     /locus_tag="L7C88_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBP9556899.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            27589..28605
                     /locus_tag="L7C88_000032"
     CDS             27589..28605
                     /locus_tag="L7C88_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBP9556900.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            28746..30047
                     /locus_tag="L7C88_000033"
     CDS             28746..30047
                     /locus_tag="L7C88_000033"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBP9556901.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            30093..30755
                     /gene="deoC"
                     /locus_tag="L7C88_000034"
     CDS             30093..30755
                     /gene="deoC"
                     /locus_tag="L7C88_000034"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBP9556902.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            30776..31174
                     /locus_tag="L7C88_000035"
     CDS             30776..31174
                     /locus_tag="L7C88_000035"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBP9556903.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            31240..32322
                     /locus_tag="L7C88_000036"
     CDS             31240..32322
                     /locus_tag="L7C88_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBP9556904.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            32534..34096
                     /locus_tag="L7C88_000037"
     CDS             32534..34096
                     /locus_tag="L7C88_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9556905.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            34089..35222
                     /locus_tag="L7C88_000038"
     CDS             34089..35222
                     /locus_tag="L7C88_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9556906.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            35222..36178
                     /locus_tag="L7C88_000039"
     CDS             35222..36178
                     /locus_tag="L7C88_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9556907.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            36277..37443
                     /gene="deoB"
                     /locus_tag="L7C88_000040"
     CDS             36277..37443
                     /gene="deoB"
                     /locus_tag="L7C88_000040"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBP9556908.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            37467..38285
                     /locus_tag="L7C88_000041"
     CDS             37467..38285
                     /locus_tag="L7C88_000041"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBP9556909.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            38302..39009
                     /gene="deoD"
                     /locus_tag="L7C88_000042"
     CDS             38302..39009
                     /gene="deoD"
                     /locus_tag="L7C88_000042"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBP9556910.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(39307..39993)
                     /gene="gpmA"
                     /locus_tag="L7C88_000043"
     CDS             complement(39307..39993)
                     /gene="gpmA"
                     /locus_tag="L7C88_000043"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBP9556911.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(40165..40746)
                     /locus_tag="L7C88_000044"
     CDS             complement(40165..40746)
                     /locus_tag="L7C88_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBP9556912.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(40879..41562)
                     /gene="rpiA"
                     /locus_tag="L7C88_000045"
     CDS             complement(40879..41562)
                     /gene="rpiA"
                     /locus_tag="L7C88_000045"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBP9556913.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            41881..42294
                     /gene="rpsL"
                     /locus_tag="L7C88_000046"
     CDS             41881..42294
                     /gene="rpsL"
                     /locus_tag="L7C88_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBP9556914.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            42378..42848
                     /gene="rpsG"
                     /locus_tag="L7C88_000047"
     CDS             42378..42848
                     /gene="rpsG"
                     /locus_tag="L7C88_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBP9556915.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            42942..45029
                     /gene="fusA"
                     /locus_tag="L7C88_000048"
     CDS             42942..45029
                     /gene="fusA"
                     /locus_tag="L7C88_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBP9556916.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            45201..46388
                     /gene="tuf"
                     /locus_tag="L7C88_000049"
     CDS             45201..46388
                     /gene="tuf"
                     /locus_tag="L7C88_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBP9556917.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            46795..47103
                     /gene="rpsJ"
                     /locus_tag="L7C88_000050"
     CDS             46795..47103
                     /gene="rpsJ"
                     /locus_tag="L7C88_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBP9556918.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            47134..47763
                     /gene="rplC"
                     /locus_tag="L7C88_000051"
     CDS             47134..47763
                     /gene="rplC"
                     /locus_tag="L7C88_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBP9556919.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            47791..48414
                     /gene="rplD"
                     /locus_tag="L7C88_000052"
     CDS             47791..48414
                     /gene="rplD"
                     /locus_tag="L7C88_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBP9556920.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            48414..48704
                     /gene="rplW"
                     /locus_tag="L7C88_000053"
     CDS             48414..48704
                     /gene="rplW"
                     /locus_tag="L7C88_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBP9556921.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            48743..49576
                     /gene="rplB"
                     /locus_tag="L7C88_000054"
     CDS             48743..49576
                     /gene="rplB"
                     /locus_tag="L7C88_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBP9556922.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            49619..49897
                     /gene="rpsS"
                     /locus_tag="L7C88_000055"
     CDS             49619..49897
                     /gene="rpsS"
                     /locus_tag="L7C88_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBP9556923.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            49920..50267
                     /gene="rplV"
                     /locus_tag="L7C88_000056"
     CDS             49920..50267
                     /gene="rplV"
                     /locus_tag="L7C88_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBP9556924.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            50281..50937
                     /gene="rpsC"
                     /locus_tag="L7C88_000057"
     CDS             50281..50937
                     /gene="rpsC"
                     /locus_tag="L7C88_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBP9556925.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            50940..51374
                     /gene="rplP"
                     /locus_tag="L7C88_000058"
     CDS             50940..51374
                     /gene="rplP"
                     /locus_tag="L7C88_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBP9556926.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            51364..51552
                     /gene="rpmC"
                     /locus_tag="L7C88_000059"
     CDS             51364..51552
                     /gene="rpmC"
                     /locus_tag="L7C88_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBP9556927.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            51577..51843
                     /gene="rpsQ"
                     /locus_tag="L7C88_000060"
     CDS             51577..51843
                     /gene="rpsQ"
                     /locus_tag="L7C88_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBP9556928.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            51901..52269
                     /gene="rplN"
                     /locus_tag="L7C88_000061"
     CDS             51901..52269
                     /gene="rplN"
                     /locus_tag="L7C88_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBP9556929.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            52306..52614
                     /gene="rplX"
                     /locus_tag="L7C88_000062"
     CDS             52306..52614
                     /gene="rplX"
                     /locus_tag="L7C88_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBP9556930.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            52642..53181
                     /gene="rplE"
                     /locus_tag="L7C88_000063"
     CDS             52642..53181
                     /gene="rplE"
                     /locus_tag="L7C88_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBP9556931.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            53200..53385
                     /locus_tag="L7C88_000064"
     CDS             53200..53385
                     /locus_tag="L7C88_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBP9556932.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            53421..53819
                     /gene="rpsH"
                     /locus_tag="L7C88_000065"
     CDS             53421..53819
                     /gene="rpsH"
                     /locus_tag="L7C88_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBP9556933.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            53851..54387
                     /gene="rplF"
                     /locus_tag="L7C88_000066"
     CDS             53851..54387
                     /gene="rplF"
                     /locus_tag="L7C88_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBP9556934.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            54548..54904
                     /gene="rplR"
                     /locus_tag="L7C88_000067"
     CDS             54548..54904
                     /gene="rplR"
                     /locus_tag="L7C88_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBP9556935.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            54925..55425
                     /gene="rpsE"
                     /locus_tag="L7C88_000068"
     CDS             54925..55425
                     /gene="rpsE"
                     /locus_tag="L7C88_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBP9556936.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            55440..55619
                     /gene="rpmD"
                     /locus_tag="L7C88_000069"
     CDS             55440..55619
                     /gene="rpmD"
                     /locus_tag="L7C88_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBP9556937.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            55663..56103
                     /gene="rplO"
                     /locus_tag="L7C88_000070"
     CDS             55663..56103
                     /gene="rplO"
                     /locus_tag="L7C88_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBP9556938.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            56103..57398
                     /gene="secY"
                     /locus_tag="L7C88_000071"
     CDS             56103..57398
                     /gene="secY"
                     /locus_tag="L7C88_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBP9556939.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            57460..58107
                     /locus_tag="L7C88_000072"
     CDS             57460..58107
                     /locus_tag="L7C88_000072"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBP9556940.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            58298..58516
                     /gene="infA"
                     /locus_tag="L7C88_000073"
     CDS             58298..58516
                     /gene="infA"
                     /locus_tag="L7C88_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBP9556941.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            58549..58665
                     /gene="rpmJ"
                     /locus_tag="L7C88_000074"
     CDS             58549..58665
                     /gene="rpmJ"
                     /locus_tag="L7C88_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBP9556942.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            58683..59048
                     /gene="rpsM"
                     /locus_tag="L7C88_000075"
     CDS             58683..59048
                     /gene="rpsM"
                     /locus_tag="L7C88_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBP9556943.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            59076..59465
                     /gene="rpsK"
                     /locus_tag="L7C88_000076"
     CDS             59076..59465
                     /gene="rpsK"
                     /locus_tag="L7C88_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBP9556944.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            59545..60483
                     /locus_tag="L7C88_000077"
     CDS             59545..60483
                     /locus_tag="L7C88_000077"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBP9556945.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            60511..60891
                     /gene="rplQ"
                     /locus_tag="L7C88_000078"
     CDS             60511..60891
                     /gene="rplQ"
                     /locus_tag="L7C88_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBP9556946.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            61163..62002
                     /locus_tag="L7C88_000079"
     CDS             61163..62002
                     /locus_tag="L7C88_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBP9556947.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            61978..62847
                     /locus_tag="L7C88_000080"
     CDS             61978..62847
                     /locus_tag="L7C88_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBP9556948.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            62837..63634
                     /locus_tag="L7C88_000081"
     CDS             62837..63634
                     /locus_tag="L7C88_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBP9556949.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            63837..64583
                     /gene="truA"
                     /locus_tag="L7C88_000082"
     CDS             63837..64583
                     /gene="truA"
                     /locus_tag="L7C88_000082"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBP9556950.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(64916..67585)
                     /locus_tag="L7C88_000083"
     CDS             complement(64916..67585)
                     /locus_tag="L7C88_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBP9556951.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(67823..68011)
                     /locus_tag="L7C88_000084"
     CDS             complement(67823..68011)
                     /locus_tag="L7C88_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBP9556952.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            68281..68643
                     /locus_tag="L7C88_000085"
     CDS             68281..68643
                     /locus_tag="L7C88_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBP9556953.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            68695..70377
                     /locus_tag="L7C88_000086"
     CDS             68695..70377
                     /locus_tag="L7C88_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBP9556954.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            70494..72530
                     /gene="recG"
                     /locus_tag="L7C88_000087"
     CDS             70494..72530
                     /gene="recG"
                     /locus_tag="L7C88_000087"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBP9556955.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            72579..73580
                     /gene="plsX"
                     /locus_tag="L7C88_000088"
     CDS             72579..73580
                     /gene="plsX"
                     /locus_tag="L7C88_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBP9556956.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            73702..73944
                     /gene="acpP"
                     /locus_tag="L7C88_000089"
     CDS             73702..73944
                     /gene="acpP"
                     /locus_tag="L7C88_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBP9556957.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            74212..75216
                     /locus_tag="L7C88_000090"
     CDS             74212..75216
                     /locus_tag="L7C88_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9556958.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            75217..76161
                     /locus_tag="L7C88_000091"
     CDS             75217..76161
                     /locus_tag="L7C88_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9556959.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            76161..77123
                     /locus_tag="L7C88_000092"
     CDS             76161..77123
                     /locus_tag="L7C88_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9556960.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            77150..78064
                     /locus_tag="L7C88_000093"
     CDS             77150..78064
                     /locus_tag="L7C88_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9556961.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            78090..79871
                     /locus_tag="L7C88_000094"
     CDS             78090..79871
                     /locus_tag="L7C88_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBP9556962.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            80219..80905
                     /locus_tag="L7C88_000095"
     CDS             80219..80905
                     /locus_tag="L7C88_000095"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBP9556963.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            80925..84506
                     /gene="smc"
                     /locus_tag="L7C88_000096"
     CDS             80925..84506
                     /gene="smc"
                     /locus_tag="L7C88_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBP9556964.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            84515..85324
                     /locus_tag="L7C88_000097"
     CDS             84515..85324
                     /locus_tag="L7C88_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBP9556965.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            85335..86333
                     /gene="ftsY"
                     /locus_tag="L7C88_000098"
     CDS             85335..86333
                     /gene="ftsY"
                     /locus_tag="L7C88_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBP9556966.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            86520..88787
                     /gene="gshAB"
                     /locus_tag="L7C88_000099"
     CDS             86520..88787
                     /gene="gshAB"
                     /locus_tag="L7C88_000099"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBP9556967.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(88876..89328)
                     /locus_tag="L7C88_000100"
     CDS             complement(88876..89328)
                     /locus_tag="L7C88_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBP9556968.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            89478..90428
                     /locus_tag="L7C88_000101"
     CDS             89478..90428
                     /locus_tag="L7C88_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBP9556969.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            90421..91380
                     /locus_tag="L7C88_000102"
     CDS             90421..91380
                     /locus_tag="L7C88_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBP9556970.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            91377..92132
                     /locus_tag="L7C88_000103"
     CDS             91377..92132
                     /locus_tag="L7C88_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9556971.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            92155..93108
                     /locus_tag="L7C88_000104"
     CDS             92155..93108
                     /locus_tag="L7C88_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBP9556972.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(93752..94048)
                     /locus_tag="L7C88_000105"
     CDS             complement(93752..94048)
                     /locus_tag="L7C88_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBP9556973.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            94403..94759
                     /locus_tag="L7C88_000106"
     CDS             94403..94759
                     /locus_tag="L7C88_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBP9556974.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            94769..95668
                     /locus_tag="L7C88_000107"
     CDS             94769..95668
                     /locus_tag="L7C88_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBP9556975.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT        31566 a        17030 c        20157 g        27119 t
ORIGIN      
        1 ttattttatt gacttagatt tattacagct aataaacagt gtgaaaagaa tgtatagtgg
       61 agacgacaac ggtgttgatt tatacaaatt tgttaccaaa catatatttg ttaatcttaa
      121 tattgacgag aaaaattacc cgtctatttt taagcactat ctatttttta ttaacgaagt
      181 agaagatcgg ataaaaaata attcattatc tagtagtgta tctagtttta agaagatgtt
      241 taaatctcga gatggtatca cacttactac agcacataaa gttaaaggaa atgagtatga
      301 tactgttatc gctattaatc ttctaaacgg gaaaattcct cattggaatg aaatttttaa
      361 tgtttctgat aaaggaatta gttcagcgag aaaactacta tacgtaattt gttcaagagc
      421 aaaaaataat ttatttcttt tctcagaggt gggttatttt acgagtaaag gagacttgct
      481 ttatcccact caattattag ataaaataga atttgattat aatatttaaa atacctaggt
      541 agtcgttgtt ttaaatatag taggaatcgg acgctcagta cggagcgtct atttttttac
      601 ccaattttga aaggaagtga acttatgaaa ataaaaaatc aagaatcaaa aggtcgctct
      661 ccccccttta aaaccatcac acaaataaga ttcattcaaa cataaaaaca gaaaggatag
      721 gtaaaaatat ggaacttaaa tatgtcattc ccaatatgga aaaaacattt ggacaattag
      781 aatatgctgg tgaagggaac attgaacaac gtcgaataaa tggcagacca accattctct
      841 ctcgtagtta caatttatac tcaacgattc aacgagcaga tgatattgtt gtcattcttc
      901 cctccgaagc tggcgagaaa cattttgaat ccgacgaaaa agtcaaactc atcaacccac
      961 atattaccgc agaaggttat aaaattggca atcgaggatt taccaattac attatgcacg
     1021 cagacgatat ggtgaaagca taagaaagga aaggtgaaaa aatatgagat tagcagaagg
     1081 tattgtgatt gaaaaagacc agacatttgg cacattgaaa ttttccgcct tgcgtcgtga
     1141 ggttcgtatc cagaatgaag atggtacggt ttccgaagaa attaaagaac gtacctatga
     1201 cttaaaatca aaaggacaag gacgcatgat acaagtcagt atccccgctt ctgttccttt
     1261 gaaagaattt gactacaacg cagaagtgga attaatcaat cctgtggcag ataccgtagc
     1321 gacggctact tttcgagggg cagacgttga ttggtacgtg aaagcagacg atcttgtatt
     1381 aaaaggacag acaaaacctc atcagaaata taaaaaagaa gcgtccgaaa gtgaaaaata
     1441 ggtgttgctt atgacaaaca caccattgat tttgaaagaa attccgaagg atgaagccat
     1501 ttcttttatt cggcaatacc attattcaaa gatactccct agattgtgta aatactttct
     1561 agggattttt tcagaagaaa aattattagg cgttgtggaa ttaggctggg gtacgcaacc
     1621 cctacaaacc atacgcaaac tctttcccga cagttccctt caaaccacag attatttaga
     1681 aattggaaag atgtgttttc ttccagaaat gaatcaaacc aattattttg gcagtcaagc
     1741 tctttcagct ctaattaagt ggttgaaaga acatacggac tgtcattttt tatatacact
     1801 ggcagatgga attgagggaa aatgtggcta tgtctatcaa gcgtccaact tcttttactg
     1861 cgggtatttc aagacaagtg tctatcgtga taagcagtca tgggaaaaga tacaccctcg
     1921 aagtgctcgc cttttattag aggaaaatgc tcgctttgaa caggtagaga aaaagcattg
     1981 gctttcccag gcattttgcg aatacaaagg gattgagaaa atcaatggac gcatgtttcg
     2041 ctatctctat ccgttgacaa aagaagcgaa aaaactgtta ggacacactc tctatcgacg
     2101 tcattattat ccgaaagaaa aaaatttacg ctttgaaaag cgaatcgctt atcagaaata
     2161 tgaagccatt tctcaaccaa cttttgataa acaggctcgt atctacaata cacaattatt
     2221 ttgataggtg gaaaggagga tttttatgcc attgcttcat gacagaggag agcgaatcaa
     2281 agccaacgat aagcacttgg tctatcattt tgtactaatt tcattgctgg tagtttttct
     2341 agtcgtccta ctcccttttc attggagagc gttacaatcg gtgaactggc aagcagttca
     2401 gttagataca tttttctatc aacttcatac gccatacttt tggagcagta ttctcactgc
     2461 tctttttgta tgcggactta tcagctggct ttattatcac tatcgtatag attctataaa
     2521 acagttagag caccgtcaaa agttagctcg tatgatttta gaaaatcatt ggtatgaagc
     2581 cgaagaaact caatcagagg gattctttaa agatttaccc agcaagaaaa ccaaacaacg
     2641 aatccgccat tttcctaaaa tatattatcg aatgaaagat ggactaatcc atattcatgt
     2701 agaaatcacc ttagggaaat atcaagatca gcttttgcac ctagaaaaca aactagaaac
     2761 aggattgtat tgtgaattag tggaaaaaac gttgaaagat tcttatgtag agtatgtcct
     2821 actttatgat actattggca atcgaattgg cattgaagac gtggtagctc aagatggacg
     2881 tgtcaaattg atggaatcgg tctattggga gttcgattct ctccctcaca tgttaattgc
     2941 tgggggcact ggtagtggaa aatcctattt tattctcaca ttgattgaat ctctcctgca
     3001 tacaaatgca aagctttata ttcttgaccc taaaaatgct gatttggcag acttaggggc
     3061 ggtcatgaat aatgtctatt accgtaaaga agatatgttg gcatgtatca atcaatttta
     3121 cgaagatatg attgatcgca gtgaaaccat gaaacaacac cctaactata aaacaggaga
     3181 aaattatgct tatcttggtt tgtctgccaa ttttcttatt tttgatgaat atgtggcaat
     3241 gatggatatg ctaggtcgtg aaagtaccac cgttattcat aaactcaaac aaattgtaat
     3301 gttaggacga caagcaggct tctttttaat tcttgcctgt caacgtccag acgcaaaata
     3361 ttttagtgat gggattcggg acaactttaa cttccgtgtg gctttgggtc gtatgtctga
     3421 aatgggcttt ggtatgatgt tcggaagcga tacacaaaaa caatttttct taaaacccat
     3481 caagggaaga ggttacgtgg atacaggaaa aagtgtgatt agtgagtttt atacacccct
     3541 tgtaccaaaa aggtacgatt tcttaggaga aataggaaaa gtcattcaaa aaaagcaatc
     3601 tgagcctgta ccgcacgaag tgaaaggtac aggttcagac ttgctttgat tggtgtggcg
     3661 ttagccacgc caatccttta gccccctcta tctaacaggg gggcacaaat acaactgaaa
     3721 acaggcaatt ctcatcaacc aatgttgatg gtacaaagga ttgcggaaaa tatgaaaggt
     3781 gtaaactcaa gggtcatagt ttacatcttt tttagattgg aggtttgcga atggaaaacg
     3841 aaaaaatttg gattaaggaa ttgaaagaaa agcgactggc ttatggcgtt tctcaaaata
     3901 aactggcggt tgcttctcat attaccagac cttacctatc ggatattgaa acaggcaagg
     3961 cagtccctac tcaacaggtg aaagaagatt tactgaacgc tttggaacgc ttcaatcccg
     4021 ataacccatt ggagatgtta ttcgactatg tacggattcg attccctacc aatgatgtgg
     4081 ctcaaattat cggtgaggtt ttacgtttga atatggatta tatgctacac gaagactttg
     4141 gctattattc ttatcccgaa cactatcgtt tcggtgatat tgttgtccta gtctctcatg
     4201 atgtaagtaa aggtgtttta ttagaactga aaggaaaagg ctgtcggcaa tttgaaaact
     4261 ttctattggc tcaacatcgg agctggtatg atttctttca agattgcatg gaacataaag
     4321 gtattttcaa acgcttggat ttagctatca acgataaaac agggattttg aatattccag
     4381 atttggcaaa gaaatgtaaa caggaagaat gcatttccgt ctttcgaagc tttaaaaatt
     4441 atcgcagtgg tgaattggtt caccgtgatg aaaaaccata catgggaaac acactttata
     4501 ttggctcatt aaaaagtgaa gtctatttct gtatatatga gaaagattat gagcaatacg
     4561 tgaaaaatga tgttccctta gaagacgcag aagtaaagaa tcggtttgaa attcggttaa
     4621 aaaatgaccg agccacccaa gccatgaaag atttattggc acatcaacag gcggaaaaaa
     4681 cagcctttga aattatcaat cgctatatcc gctttgcaga taaagacgac actaaacgtc
     4741 ggagtgattg gaaaactaat gaacgttggg aatggtttat cggtaaaaat cgtggagcat
     4801 tacgcctaac cacacagcca gagccttatt cttttgaacg aacattgaac tggttacatc
     4861 atcaagtcgc ccctacatta aaaatcgcaa gcattttaga tgttctcaac ggtacaacca
     4921 ttatctccac catgattcag gaagccaaac tgacagaaaa acatgagaaa ttaattgaac
     4981 aacaacatct agccatggag gatttgatta catgagcctt ttaacaaaag aattaaagaa
     5041 gttagggttt cagtgtggca ttgagtttca agcgtatata caaaatacag ggaaatatac
     5101 gtctctcatt attgagggaa aacggcaagc tggtgatacc atctatacct atgattttta
     5161 caaggtgaga ttttataata attataccaa tcgagtaacc gtctatggag agcatttaac
     5221 cccttttcaa ttattaaggc gtgtaaaaag ctatatctat tatcgagaaa aatatcttaa
     5281 ggaaaggagg acaatcacat gaattttggg cagaatttgt acaactggtt cttggataat
     5341 gcacagtcat tggtattgtt agcgattgtt gtcattggac tgtttttagg ttttaaacga
     5401 gaattttcaa aactcattgg cttcttgatt attgctctaa tcgccgtcgg acttgtgttc
     5461 aatgcagctg gcgtgaaaga tgtgttatta aacttattta accgaatcat tggtgcttaa
     5521 cagatatttt tcatgataaa ataggaagta tatattttgt tatgaaagga tttatgaata
     5581 tgtttacaaa tgatcaattt aaatctcttt taattaaaac attagaaaga aagagctctt
     5641 caaattatta tgaaggaggt aacgagattg tttctaaaat gaaaatatca gaggtaactt
     5701 tagatgagac tgacgatttt acttattata aaggatataa aaagggctgg aatacgcttt
     5761 gcacatatct taaaataaga gttccttttg atgatttaga cttttttgaa agtcataaag
     5821 atttgattac ccagacagca agctccatat atgataaaca aggtgataat gtattagtgg
     5881 atactatttt agtaccactt ccagagaatt acgaagtaat taactttagt cagttgaaaa
     5941 ttagtgatgt ggtttcacaa gctattgaag acgctgagtc ttttatgagt aatggtgaat
     6001 atcaacgtgc ctttgacaga gttcacactg cttttcatgg atatttaatt gaaatactaa
     6061 aaaaatatga aattacagtt cctagagacg aaaatctatc taaattatat agtaggatac
     6121 aacaattaat tgaaaaagaa attcaaccta ctgaacttgc tgatatagtg aagacaacga
     6181 taaggtcatc aaatggaatg attagctctc ttaatgaagc aagaaatagg cattcacttg
     6241 cacaccctaa tacaaatatt attggaaaga gagaagcaaa actaataata ggtatttcaa
     6301 gtacagttac agattatatt agcggatacc ttgataagta gcgtcattaa ctgattgcta
     6361 ctttttttat gactattttt ataaaaagga tgtgataaga attggaaatg aaagtctatg
     6421 tggcaaattt aggacggtat aatgaaggtg aattagtcgg agcatggttt actccaccaa
     6481 ttgatgagga agaaatggca gaaagaatcg gtttaaatga ggactacgaa gaatatgcaa
     6541 tacatgattt tgagcttcct tttgatgtgg acgaatacac gccgattagt gaaatcaacc
     6601 gtctatgtga agccattcaa gaaatcgaag gtacacctat ttataatgaa ctcaaagaaa
     6661 ttcaaggcat gtggtttagt agcttggaag aattactgga aaacaaagag gatattcatt
     6721 gttatagtga ttgtgattcg atggaagatg tcgcccgtta ttacgtggaa gaaacaggac
     6781 agcttggtga agtcccttcc aatttacaaa attatattga ctaccaatct ttgggacgtg
     6841 atatggaaat agagggtaat tacctagtta cctctcatgg ggtatttgaa tattgtcagt
     6901 aagtttaaca atccgtgtta taattaaatt aataaatagc acggagaggt ataaattatg
     6961 gtaaatgtat ttgaaaatct taaactatta aaactagaca tgaaagataa aggctgggtg
     7021 atagattcct tttactttcg ttacaaacag caaaattata ttgtacttgt taagctattt
     7081 gaaaaagagg aaaaagttcc agaatatgct ctgttaaaac tagaattttt aaaggaaaac
     7141 gatttttcag atatgctagc tgtctatgct aattcggtaa aattatatac agacacgaaa
     7201 acaataagag aatattttgg tatcgaatac agtagtaact tgggagatgt tttatttcaa
     7261 tttagccaaa ctcttgctcg atttattccg acagaagtta gtgagaagaa aaatgaagac
     7321 caaaaagaag ccatgtgttt ctcattaagt caaagtgatt cagaagatcc cagaaaaaaa
     7381 tattgttttt cagttagaag aaatccttta aagggaaatg gtgagctggg aaaacgaagt
     7441 ccttttaatg acaataaaac gagattgtat agacccagct tatatgaacg attagggtca
     7501 gataccaatt taagtttcag atattcaatg aatccagatg atgaagaaac tgatgaaggt
     7561 attattgcaa aatggacaaa aaataaaatt gaatagttaa agcattgaaa gagcaatcac
     7621 ctattttgat tgttcttttt ctatttttac ggaaaggacg tgaagacatg aaaaaaataa
     7681 gaagttacac cagtatttgg tcagtagaaa aagtgattta tgcgattaat gatttacaac
     7741 tccctttccc aattaccttt acgcaaatga catggtttat cgtttctttg tttgtcgtca
     7801 tactctttgg cagtttacca ccactttctc tgattgacgg agcactactc aaatacttag
     7861 ggattcccat tgttctcact gggttcatgt gccaaaagac ctttgacgga aagaaaccct
     7921 atggatttct aaagtctatc attacctatg ctctacgccc taaagtaacc tacgctggca
     7981 aacaaatacg attaaaaaaa gaaacaatga atgaatcgat tacgattgta aggagtgaac
     8041 aactagatgg catatccgat taaatatatg gaagataatc tcgtatttaa tcatgatggc
     8101 gaagtattcg cttattatga attaattccc tataattaca gttttttaag ttccgatgaa
     8161 aaaattcaag ttcatgataa tttctgtcaa ttgattgccc aaaatcgtga tggcaagatt
     8221 catgctctgc aactagcaac cgaatcaagt attcgagcca cacaggaaca atcgaaaaaa
     8281 gaaatcactg gacgattaaa agagatagct tacgaaaaaa tagatgaaca gaccgaagcg
     8341 ttaatttcta tgattggtga caatcaagta gactatcgct tttttattgg ttttaaactc
     8401 tacctcaatg aacaggaagt atccgtaaaa aatgttggga aagaaattca aaaagcattt
     8461 gcggaattct ttcatggtgt gaatcacaaa ttaatgggcg attttgtttc tatgcctatg
     8521 gcggaaatcg aacgcttttc taagatggaa cagttgttag aaagtaaatt atccagacgc
     8581 tttcagattc gtaaattgga gaaagatgat tttggttata ttattgaaca tctttacggg
     8641 caaacaggtg tcccttttga tgactacgac taccatttac cgaaacgata cgaagataaa
     8701 aaagtgttgg taaagaaata cgatattctc aaacccactc gctgtttaat cgaagaaaat
     8761 caacgctatt tacggattga acaggaagat accactactt atgtggcgta ttttacaatt
     8821 aatagtattg ttggtgaatt ggatttccct aatagtgaaa ttttttatta ccagcaacag
     8881 cagtttactt tccccgttga taccagtatg aatgttgaaa ttgtcgccaa taaaaaagcc
     8941 ttatctaccg ttcgcaataa aaagaaagaa ctgaaagatt tagatagcca cgcatgggaa
     9001 agcgacaacg aaaccagtac taatgtggtg gacgctttag aatctgtcga tgaattagaa
     9061 agtaatttag accaaaccaa agaatctatg tacaaactaa gctatgtggt acgggtatca
     9121 gcaaagaatt tggacgagct gaaacaacgt tgtgatgaag taaaagattt ttatgatgat
     9181 ctgtctatca aattagtacg accttttggc gatatgctag gcttgcataa tgaatttatt
     9241 ccctcaagca agcgatatat caatgactat attcaatatg tcacgtcgga ttttttggct
     9301 ggtcttggtt tcggtgctac acaaatgatt ggtgaaaatt ctggtattta cgtcggttac
     9361 aatctcgata caggcagaaa tatttatctc caacctagcc ttgcaagtca aggaattaaa
     9421 ggctctgtaa caaatgcatt agcgtccgct tttattggtt cattaggtgg cggaaaatca
     9481 ttctctaaca atatgctggt ctattattca gtactctttg gcggacaggc aaccattgtt
     9541 gacccaaaag ctgaacgtgg tgaatggaaa gaaaccttac ctgatattgc ccatgaaatc
     9601 aatattgtta atctcacgag tgagaacgac aataaagggt tacttgaccc ttatgtgatt
     9661 ttaaaactcc cgaaagattc agaaagcctt gccattgata ttctcacgtt cttaacaggt
     9721 atttccagcc gagatagcga gaagtttcct gtcctgcgta aagctattcg gagtgtaact
     9781 caaagcaaac aacgagggtt gttattggtg attgatgaat tgcgaaaaga agatacgccc
     9841 atcagcaata gtattgctga ccatatcgaa agctttgtcg attatgattt tgcccatctg
     9901 ttattcagtg atggcagtgt cacccaatcc attagcttgg aaaaacaact caatattatt
     9961 caagtggcag atttggtctt acccgattcc aatagctctt ttgaagaata cactaccatg
    10021 gaattattaa gtgtggcaat gctgattgtc attagtacct ttgctttaga ctttatccac
    10081 tctgaccgtt ccatttttaa aattgttgac cttgatgagg cttggagttt tttacaagtg
    10141 gcacaaggaa aagctctatc tatgcgattg gttcgagcag gacgtgccat gaatgcaggg
    10201 gtctatttcg ttactcaaaa cgcggacgat ttactagatg aaaagatgaa gaataatatt
    10261 ggcttgaaat ttgcctttcg ttccactgac ctagtggaaa tcaaaaagac cttagaattt
    10321 tttggtgtgg acaaggaaga tgaaaacaat cagaaacgct tacgtgaatt agaaaatgga
    10381 caatgtttag tttcagacat ctatggtcgt gtaggggtta tgcagtttca cccgattttt
    10441 gaagagttgc ttcatgcctt tgataccaga ccgcctgtgc gaaatgaggt ggaagaatga
    10501 cacaaaaaca aaagaaattt cttcactata gttggataac gctcctttgt gtgggcgtta
    10561 ttttactttt attaggcacg ctgggcaatg cagtacaagc gacaggctta gttgatgaaa
    10621 ccattgatac aagcaatgaa tactccaagt atggtttgaa tcaatatcag cttgattatt
    10681 atgtggacaa tagctggggc tggcttccat ggaattggag tgatggcata ggacaatcgg
    10741 tgatgtatgg attgtatgcc attactaatt ttatttggac aatttctctt tatctatcga
    10801 acgccacagg ttatttggtg aaagaagcct atgccttaga tttcattagt caaacatccc
    10861 aagcaattgg cgaaaacatg cagacgattg caggcattac accgaatggc ttttccagtt
    10921 cagggtttta tgtcggtttc ctccttcttt ttattctcat tgttggaatc tatgttgcct
    10981 atacaggatt ggttaagcga gaaacgacga aagtgatacg agctgtttta aactttgtcg
    11041 tggtgtttat tctatcggct tcctttattg cgtatgcacc cgattatatt gcgaaaatca
    11101 atgatttttc caaagatgtc agtaccgcca gtctgaatat tgggacaaaa attgttcttc
    11161 ctaacacgga tagtcaaggg aaagacagtg tggacatgat acgtgacagc ttattctctg
    11221 ttcaagtaaa gcaaccatgg ctattgcttc aatatggctc cactgatgta gaagcgttag
    11281 gggaagaacg tgtggaaagt ttattgtcta ccagtccaga tacaaacaat ggtgaagata
    11341 gagaaaatgt agtgattgaa gaaattgaag atcatgacaa tacctattta accctaccga
    11401 agacgatttc cagattagga acagtcttct ttttgtttgt attcaatatt ggtatctcga
    11461 tttttgtttt ccttctaaca ggaatcatga ttttttcgca agtgctattt attattttcg
    11521 ctatgttttt gccaatcagt ttcctattaa gtatgttgcc gagttttgat ggcatgggca
    11581 ggcatgccat taccaagtta tttaatgtga ttatgacaag ggctggtatt accttgatta
    11641 ttaccgttgc ctttagtatt tccactatgc tttattcgct gtcagcaagt tctccctttt
    11701 tcatgattat gtttttacaa attgtgacct ttgcagggat ttattttaaa ctgggcgatt
    11761 taatgagcct attcacttta caaagcaacg actctcaaaa catgggcaga caagtgtttc
    11821 gcagacctcg tcaaatgatg aatcgacaaa ccagaagatt tcaacgcagt atgagtaaga
    11881 tttttcgtgg aaaagcaggg tcaacgaagc aaaagacaat gacaacaaag cagaatcaaa
    11941 ccaataaagc taaccatact cgtcaaaatg aacggactac accaaagaaa gaaacagcac
    12001 tttccaatgt gaaaaagcaa caaggcggta tcgggcaacg attaggtgaa aagacagccc
    12061 atgtattgga cacgaaaaat cgtctagtca ataaaagaaa gcaggcaaaa caacagatac
    12121 aggcgacacc aacccatgtc aaatatgccc ttcatcaagg aaaagagaat gtcactcata
    12181 atgtaacaga ctttaaacaa tctatggcag ataccaaagc tcaacgcaaa caacagcgta
    12241 tgaaccagca ggagcaaaaa cgaaagaaca ttgctcaaaa gcgtttggag ctggataaag
    12301 caaaagaaaa aagacgaaaa gaaaacccat catctcctgt tcagaataac cagcagcatg
    12361 ttcgcaagcg tcagcaaacc gtcacgcctg ttttgtcaca aaacactaaa cgtgaaaatc
    12421 atcagcgacc attgaaaaaa gagcaaaaac aaaagacacc accgaagcaa ttcaatcaga
    12481 ggaagctaaa taaaagaacg gataagcgag gacaacaaac atgaagctaa aaataacagt
    12541 gatttgtagt gtggtcttct ctctcttctt ttttctctta ttattcctag tcattttctt
    12601 tgcagatgat acggacagtg gcgaaaacaa caaggattct tctattccac aaggcggtgt
    12661 gaccgtttca ccagaagtgt tggcacaccg tccgttgatt gaaaaatatg gtaaggaata
    12721 tgggattgaa gactatgttt cttatatctt agccattatg caagtggaat cgggcggtac
    12781 agcagaagat gttatgcaaa gttccgaatc tttgggttta ccgcccaaca gtttgagtac
    12841 cgaagagtcc atcaaacaag gggttaaata tttcagtgaa ttattaacca gtgcagaaca
    12901 acaaggagtg gatatagatt ctgttatcca atcttataat tatggcggtg gctttttaaa
    12961 ttatgtgagg agtcatggga aaaaatatac ctatgaatta gccgaacagt tttctaaaga
    13021 gaagtcgggt ggtcaaaaag cagactatcc caatcctata gccatacctg tgaatggtgg
    13081 ttggcgatat aactatggaa atcagtttta tgttcagttg gtttcacaat acctaaccga
    13141 cacttcccca acagaatttg atgatgaaac cgtgcaagtc attatggacg aagccttgaa
    13201 atacgaaggg tttccctatg tctttggagg ggcgtcgcct accacctctt ttgattgtag
    13261 tggcttaata caatgggtgt atgacaaagc tggcatttct ctccctcgtg tcgcccaaga
    13321 tcagtatgac gctacgcaag aaatctctat ggaagaagcc caagcaggcg accttatctt
    13381 ctttcattca acctataatg caggcacata tgtgactcat gtggcgatat atttagaggg
    13441 aaatcgcttt tatcatgcag gcgacccaat cggttatggc gacttaagca gtcgttattg
    13501 gcaagaccat ctgattgggg ctagacgtgt tattcataac taagaaagga atgaatcaaa
    13561 tgattataaa aatcgagcga aaagaaaaga aggagaaacc aaagaaatct aaaaaaccga
    13621 gcaagcaaag aaaagttccg atgattaaag ttggcacgca taagaaatta acctttgttt
    13681 tatgggtttt attgattggt agtgtcggat ttggaatcta taaaaatttt actgccattg
    13741 acactcatac tgtccgtgaa acagaaatca ttaaacagca gattgtcgat accaaccaag
    13801 tagaaagttt tgtgaaatcc tttgcgaaag actacttttc gtggcaacaa tcccaagaag
    13861 ccattgataa acgaaatgaa aaattgaccc attatttgac ggaagaattg caggtattaa
    13921 atgaagaaat gattcgtaag gatattccta ctagttctag tgtgaacgat atacaggtgt
    13981 ggcaggtttc tcaagtgaat gagaacacct ttgaggtact gttttctgtt gaacaagtta
    14041 ttaccgaaga caaagacaag gaaactatat cgtctagctt tcatgtggtt gtccatatag
    14101 atgaatcaga taatatggtt attatcaaaa atccgacaat gagtaagaaa cctcaaaaat
    14161 cggactacca acccaaacag ctagaaagtg accatacagt agatacagaa acgatggacg
    14221 aaatcactag ctttttagaa acgttcttcc agctctatcc taccgccaca gaaaaagaat
    14281 tgacttacta tgtaagtaat catgtgttac ctatgattaa caaggaatat gttttcgagg
    14341 aattggtgaa tcctatcttt accagaaaag ataaccaagt aatcgtgaat gtcgctgtga
    14401 aatatttaga tcaagaaaca aaggcaaccc aaatctcgca atttgagttg atattagaaa
    14461 aacaagataa ttggaagatt gtaaaataac aaatattggt acatgattac agatactttg
    14521 taatcatgta ctctttttga taaaaaattg gagattcctt tacaaatatg ctcttacgtg
    14581 ctattattta agtgactatt taaaaggagt taataaatat gcggcaaggt attcttaaat
    14641 aaactgtcaa tttgatagcg ggaacaaata attagatgtc cttttttagg agggcttagt
    14701 tttttgtacc cagtttaaga atacctttat catgtgattc taaagtatcc agagaatatc
    14761 tgtatgcttt gtatacctat ggttatgcat aaaaatccca gtgataaaag tatttatcac
    14821 tgggattttt atgccctttt gggtttttga atggaggaaa atcacatgaa aattattaat
    14881 attggagttt tagctcatgt tgatgcagga aaaactacct taacagaaag cttattatat
    14941 aacagtggag cgattacaga attaggaagc gtggacaaag gtacaacgag gacggataat
    15001 acgcttttag aacgtcagag aggaattaca attcagacag gaataacctc ttttcagtgg
    15061 gaaaatacga aggtgaacat catagacacg ccaggacata tggatttctt agcagaagta
    15121 tatcgttcat tatcagtttt agatggggca attctactga tttctgcaaa agatggcgta
    15181 caagcacaaa ctcgtatatt atttcatgca cttaggaaaa tggggattcc cacaatcttt
    15241 tttatcaata agattgacca aaatggaatt gatttatcaa cggtttatca ggatattaaa
    15301 gagaaacttt ctgccgaaat tgtaatcaaa cagaaggtag aactgtatcc taatatgtgt
    15361 gtgacgaact ttaccgaatc tgaacaatgg gatacggtaa tagagggaaa cgatgacctt
    15421 ttagagaaat atatgtccgg taaatcatta gaagcattgg aactcgaaca agaggaaagc
    15481 ataagatttc agaattgttc tctgttccct ctttatcatg gaagtgcaaa aagtaatata
    15541 gggattgata accttataga agttattact aataaatttt attcatcaac acatcgaggt
    15601 ccgtctgaac tttgcggaaa tgttttcaaa attgaatata caaaaaaaag acaacgtctt
    15661 gcatattaag tagttcagtt ttggagtaca aaaagtgaaa atgtaaacct aaatgagtat
    15721 caaattgcaa ctgaatttga tactcgtttt ttattgttaa atcaacgttt gttgttaatt
    15781 tacaccacaa aatgtaagtt aaaatgtata taaaaatgcg aacgtgaaat aattattgta
    15841 ggaatgcaaa ttggtgtgtt aaaatggtta caatttacta agcaaaaagg ggtgcatttt
    15901 cctatgcaat ttcttgagcc aaaaaataag aacgctaagt ctgtggattg ggaaatatca
    15961 gagcaagtaa gggtgatagt taagcaatac gctgaatatg cagagcgtac tgaaagcgaa
    16021 gcagtggatg aattcttatt gaacatttta gacgataaga agtttattga atggattgcc
    16081 aacaagcgaa gtaataagcg gattgttgaa aaaatgggta tcaaagatag agtgggttga
    16141 tagacaatga ccaagcttaa aagattagcc acgaaggaag atgaaattgt agatgttaaa
    16201 attccgattt caaacgaaga attaaaagat agggctaaac aatatgattt attaactcca
    16261 aaacgatttg caacaaggta taacaaaatg ttgttcttgc caacgtcttt taaatggaac
    16321 ggttctgaat atcccattca atataattac tgcatcaatc cgttttgttg taattttggg
    16381 aaagaacagc acaaattcaa agatgtaaaa gggaaaccaa gtcgatataa aatgactggt
    16441 agttccaaag ataaaggtca taaaggtatg tactgcaatg acaatcctat tggcagaggt
    16501 gtatcgcaaa actgtacagt aaccccttta tctaattggt ctgttgttga agaaattaaa
    16561 cgccttatag aaatcaatag catccaagat gttgagccag attatcaatt tcataaagaa
    16621 ggctgctcgg aagaagaatc aaccccattc aatgagccga agcaatttta caaaaggggg
    16681 aaaagtaggg gcaaatctca acgctatcaa tgtaaggcgt gtaagaagtt cactaatgtt
    16741 ctaccaaaaa gagaagaaac cactacttat caccaacaaa agaacaccat tcttccaatg
    16801 ttcgctaaga tggttgttgg aagggtttca gtcagtcgta cttgtgatat tttaggaatt
    16861 ggagttggaa cctactatca taagctggag tggctgtata ggcgttgttt ggagttttta
    16921 gaacgatatg agacacaacc ccttcaaaca aagaaattta acgagatgtg gcttaatacg
    16981 gacaagatgc actactacct aaataacgtc cgtaagaaag gacaaggttc aaagaaatat
    17041 acggggtttg aagaccttaa tatgcaaacg tatatagttg tatctgctga ggtcttatca
    17101 agatatgtgt tccgttctga tgttgcctat gattggaata tttcaatgga tgaattaaat
    17161 gaagatacaa gaaaattcaa agaagaccat ctcaatactt ttagtcgtaa aaatgatagg
    17221 ttagattggt cttattatcc acaagaacca tccgctaacg atagcgaaaa taggaatgct
    17281 tatcttcacg aattagggaa aattactaat aggagtagat ttgtcgatgg tttaaatgtt
    17341 gatgctcctt atactacaac tgctcactat tggttaatta aacaaatggt taatgccgac
    17401 gaatggcgaa tgattagtga tgatgacttc tctattagaa acgcctttta tagagtattc
    17461 acgaaagaat taaggttgag cgatgcacat cattttattt gccaagttaa caagacgaaa
    17521 agcagaaaac aatgcttaaa agaattcgga caagcaaaag cagaactgct cgattgggga
    17581 gatatcagag gattcaaaac aaagtttcta cggactttgg catctcatta tctaactgaa
    17641 ttactaacaa gtcatcaatt ccacgaagag gctattagta aagatggaga aagatatcgc
    17701 aaatatgccg ataaccctat caaacatcca ttagccacta aggataaagg attttattca
    17761 gttgattgta gaacggattt atctgctctg gaaccaaacg aaatcgcaaa gatgctatta
    17821 aatgttaatg accattcgac caatagcttt attcaacaga taagacgtta tatatcatct
    17881 cttgaaagac cattaacaac agctcgtggt gataagaaga gctatattta cgctaacttc
    17941 aatccgaagt atgctcaatt tgcgattaca attctaagaa cttactacaa cttttgtcgc
    18001 ccttttaaat cagcggataa aaaggttttg acacctgctc aaagattagg gattacagat
    18061 aaacaatttg attggaaaga tataatttat ttcaaatgac aaaaagagct tggagtaatc
    18121 ccaagctctt gtgctttatc tttactgttc ttcttcaatt aacgcacccg ttaactcaat
    18181 aagttttttc tttcatatac atgaaaatag tagttatacg gatttttatc attctttatc
    18241 cctttttggg caaatacctc attccattcc tcataattca cttctggaaa aaaagtatct
    18301 ccttcgaatt catgatgtat ttttgtgatg tacattttct caacataagg gaaaaacaaa
    18361 ttataaatct gttctcctcc gaaaataaaa atttcttctt cgtttttaca taactcaaaa
    18421 acatcttcta ttgaatgaac aatttcacaa ccattaaagg taaacccctt atctctcgtc
    18481 agaataatat ttcttctgtc aggtaaggct cttccgattg attcaaggtt cttcctacct
    18541 aatattatcg gatgtccctt tgtagtattt ttaacatatt cccagtcctt gggaatcctc
    18601 caaggaatgt cattctcttt gccaatcact ctattcttat ccatcgcagc aatcaaagaa
    18661 actttcattt ataacacagc ctttttaact aatttaccat ctaatttctt atttctatca
    18721 aaaaaccttt tctcattatc ctgcccgtta gttgaataag caattttttc tataagttat
    18781 attatcataa taccacaaaa tcacaaattt tcattcaatt atcattttca attgcatttt
    18841 ataaatcatt ttgtatgtaa tttggtatgt aagttaaaat gaaaaaagta gtccattttg
    18901 aagtacattt tgtcattttg tactccaaaa ctgaactact tacttgcata tatacgcctt
    18961 tatagtggag tactacattt acgagattcg gttagagtat cagaaaaaga aaaaataaaa
    19021 gttacagaaa tgtatacttc aataaatggt gaattatgta agattgatag agcttattct
    19081 ggagaaattg ttattttgca aaatgagttt ttgaagttaa atagtgttct tggagataca
    19141 aaactattgc cacagagaaa aaagattgaa aatccgcacc ctctactaca aacaactgtt
    19201 gaaccgagta aacctgaaca gagagaaatg ttgcttgatg cccttttgga aatctcagat
    19261 agtgatccgc ttctacgata ttacgtggat tctacgacac atgaaattat actttctttc
    19321 ttagggaaag tacaaatgga agtgattagt gcactgttgc aagaaaagta tcatgtggag
    19381 atagaactaa aagagcctac agtcatttat atggagagac cgttaaaaaa tgcagaatat
    19441 accattcaca tcgaagtgcc gccaaatcct ttctgggctt ccattggttt atctgtatca
    19501 ccgcttccgt tgggaagtgg aatgcagtat gagagctcgg tttctcttgg atacttaaat
    19561 caatcatttc aaaatgcagt tatggaaggg atacgctatg gttgcgaaca aggattatat
    19621 ggttggaatg tgacggattg taaaatctgt tttaagtacg gtttatacta tagccctgtt
    19681 agtactccag cagattttcg gatgcttact cctattgtac tggagcaagc ctttagaaaa
    19741 gctggaacag aattgttaga gccatatctt agttttaaag tttatgcacc acaggaatat
    19801 ctttcacggg catataacga tgctcccaaa tattgtgcaa atatcgtaaa tactcaactg
    19861 aaaaataatg aggtcattat tattggagaa attcctgctc gatgtattca agattatcgc
    19921 aatgatttaa ctttttttac aaatgggctt agtgtttgtt tagcagagct aaaaggatat
    19981 caggttacca ctggcgaacc tgtttgccag acccgtcgtc taaatagtcg gatagataaa
    20041 gtaagatata tgttcaataa aataacttag tgcgttttat gttgttatat aaatatggtt
    20101 tcttattaaa taagatgaaa tattctttaa tatagatttg aattaaagtg gaaaggagga
    20161 gattgttatt ataaactaca agtggatatt gtgtcctatt tgtggaaata aaacaagact
    20221 acgaatacga gtggatacta tacttaaaaa tttcccttta tactgcccca aatgtaagaa
    20281 cgaaacttta attaatgttc aaaaaatgaa tataataaca atcaaagagc cagacgccaa
    20341 gacgcagagc cgataatttg agaaatgaaa ctctcatctt atcggctctt tttgtttatc
    20401 tgaattttac tgactagcct tcaatatttc ttgcttcatt gatacctttt gctagtgctt
    20461 ccattaagga tagttctttg tctgtaaagc tatccatgta tttttctacc tgtaaccttc
    20521 gagtgctttt aatcaaatta tctgtaggta agaaaaattc atcaatagat acatggagta
    20581 atgatacaag atcatacagc acttgtgtac ttgggtgttg tcctttgttt tctatatttg
    20641 ttaaataacg tgggtcaatt tcaatcattg ttcccacttg ttcacgagtg agaccccgtt
    20701 tcattcgagc ctctttaatc gctaaaccaa cggctctaaa atcgtattta tcttcttttt
    20761 tacgcatact aaatcacctc tatacatttt actgttccta tataaccata aacaggtata
    20821 gaaaaacatg ttatatagtt tatgagttcc tatagaacac tgtggaattt attaatgcga
    20881 tgaatccaat ttcaaataga aaggtcgctg attttattta cctatacaac tttataaaat
    20941 ttagtcatac tcctagaaag tagataaaat tggcgactta atggagggaa aagtcgccat
    21001 gagaaagata atctgtcatc tagttctctt aattaagttc ttatcaaaaa aacttatcca
    21061 cctgtactgg atagatatga ccatcaatgt ggttttgcag attacataga tagaaaaatc
    21121 aaagcatatg aacagagaaa acaatctgtt tatgtgcttt tttggtcact taataaatat
    21181 cttttaggat ttctcttcat ttatgcaaca aatcccccgt tcgtgtcggg gtttagtatg
    21241 aagggagata aagaagcaca tgccactccc tttcacgaca gaaagggggt gaaaagcatg
    21301 aaaccatctt cttttcaaga aaccatagaa aatcagtttg actatatctg caaacaagtt
    21361 attgaagatg aacgaaaaga ttacttcaaa catctagaca gactatcagc aaaagaagtc
    21421 tcgttttctg atatagataa ctaccttgtc aactcttttt ctactgttga tacgtacgtc
    21481 actgatttcc aactatttaa attatttgga ttaagaatca atgttgaaag tgatttatta
    21541 agtgaagccc tgcgtcatct ttcagagaaa aaacggaaca ttattttact tcattacttt
    21601 atggatatga gtgatgtgga gattgcggag ttactaaatt tgaatcgttc gactgtttat
    21661 cgtcatcgaa taagtggact agccatgatt aaagaattca tgaaggagtg taaagaatga
    21721 aaacagctta tccaagggtt cccttccccc tcattgtaaa ggcgacagat ggcgacgtgg
    21781 aagcaattaa tcagattgtt aaacattatc gagggtatac ctcaaaacgt tcattacgtc
    21841 gcatgacaga cgaatatgga aattctcata tggttattga tgaaacccta cgtggcagaa
    21901 tggaaacgaa actcatctct aagattttat cgttcgaaat taaatagtcc cattttttcg
    21961 tggaagcgtg tcgaatcgta tccacgcttc ccgatttggg aggtttgtta ttccatcaaa
    22021 gcatattgtg tgttcagtag gttttgatag gctaacaagc caaacgttct ttgacaacca
    22081 aataaaggca atcgaatacg tttcggtaag aaaagagctg atgaactaac acgccatgac
    22141 ctacaaaatt agtgagcgat tcatgttagt aattcgaaag taatctttag caggattgct
    22201 gccatgactt tcttatcgtg ataatgatac tcccgtatag ccatagtccg agcgttagaa
    22261 gcgtcacagg caatgggtac ggctacatga gaaccatgca gaagtgaaat tcctgtgagc
    22321 tttgctagag ctgttcgatt gctaagatat tcttctcttg tcagtgtatt attataaaac
    22381 tatttgatat aattataggt gaatattgga gttttcctag cctataattg ggaaaggagt
    22441 aataatgata acggtcacaa aaaaggattt agttgagcta ggatatggaa cttctttttc
    22501 agcagacatc ataaaaaaag caaaagaatt gatgattaca aaagggcata tctactatca
    22561 atctcgaaag ctagatagag tccctcgtga agctgttgaa gaaattctag gaattcggtt
    22621 ttcaaatgaa aacaggtctg agtagttttt gcacagtaag gagtaaaaac tatggttaaa
    22681 gacccaataa aaaaagcaaa gaatggaacc tattattttc gtgcaaatct aggttatgat
    22741 tctaaaggga aaaaaattca aaaatatcgt agtggattca ctactaaaaa agaagcaaga
    22801 gaagaatatt cgaaactgct attgatgaaa ccagaagaat taagtgagaa taaggataaa
    22861 atgacgttta aacattatat ctttgaaatt ttccttccat ggtataagac acaggtaaag
    22921 ctcagaacat atgaaaatcg cttaccaact attaagaagc atttctctta ttttgataaa
    22981 atggctgttt ccgatattga gcctattgat gtgcaaaatt ggcaactaaa attatcaaag
    23041 aagtgtaagt cttcttatgt aagagctgtt caaggactat tttcagttgc tatggatcga
    23101 gcaattgtcc ttgggataac caccacaaat ccatctaaga ttattggcaa tgtgaaaaag
    23161 caaaagtcta aaattgaatt ttggacaaaa gaagaatttg aaaaagtaat ctctctaatt
    23221 tacaaagaag attactatca acacttttta tttatctctc tgtggttttt atttatgact
    23281 ggaatgcgaa ttggtgaagc tactgccatt caatgggaag atattgattt tgactcagga
    23341 gtactaacca tcaacaaaac actctattac aagaatcaat cgaattatag atttgttgaa
    23401 ccaaaaacaa aggcgagcgt tcgtcatatt gtattagata aatgcacatt aacttattta
    23461 tccgaatgga aggaagtaca acaaaatcta attcagacag actttgtaat gagctataac
    23521 ggtattccta cccaaaaaca tacactatca tatgctattg aacgctatgc taagctggct
    23581 ggtatccatc gaatcagaat ccatgggtta cggcattctc atgcttcctt gttaatcagt
    23641 atgggagaaa atccacttat cattaaagat cgtctaggac acgaagatat tgagacgact
    23701 ttaggaacgt atggacatct ttatcctaac agtaatttcg aggtagctaa caaattaaat
    23761 ggagccattt cctttaaaga agcaaaacaa aattatgata cttcaccaaa gaatcaattt
    23821 actgtagact acttgcgaaa caaagaaatg aaaaaagtgc aataaaagtg cagtaaaaag
    23881 ataagaagag ccagaaaccc ttggtataag aggatttcta gctctcctac aactattccc
    23941 actccactgt tgctggtggt ttagaagtga tgtcatacac gatacggttg acgtgggcta
    24001 cttcgtttac gatacgtaca gagatttttt gcaagacttc ccatgggata cgggcaaagt
    24061 cagcggtcat tccgtcgatt gaagttacag cacggatacc gactgtgtag tcgtaagtac
    24121 gtccgtcacc cataacaccg acagagcgga tccctggaag aacagtgaaa tattgccaga
    24181 tatcacggtc aagtccagca gctgcgattt cttcacgcaa gatagcatca gattcgcgta
    24241 cgatttctag cttgtcttca gtgatttcgc caagaacacg aataccaaga ccaggaccag
    24301 ggaatggctg acgccaaacg attgaatcag gcatgcctaa ctgagtccct aattcacgga
    24361 cttcgtcttt gaataatgtg tttaatggtt cgatcaattc aaattgcata tcttctggca
    24421 gtccacctac attatggtga gatttgatcg tctgtgctgt ttctgtacca gattcgataa
    24481 cgtcagtata caacgttcct tgtgctagga aagagacgcc ttcttcacca gcaagttttg
    24541 ttgcttcgtc atcaaaaaca tatacgaatt cattcccaat gattttacgt ttttgttctg
    24601 ggtcagatac acctttcaac ttgtctaaga agcgatctct tgcatcgact ttgatgatgt
    24661 tcaagccgaa ttttccgcct agactttcca ttacttgttc cgcttcgcct ttgcgtagca
    24721 gaccgtggtc aacaaagata gatgtcaatt ggtcaccgat cgctttttgt aaaagaaccc
    24781 caacgacact agaatcaacg ccacctgaaa gaccaagcaa gacttttttg tcaccaactt
    24841 gttcacggat tttttctact tgcatatcga taaagttatc cattgtccag ttaccttcac
    24901 agtgacaaac atcaaaggca aagtggcgca gcaattcgat tccgtattcg gaatgacgta
    24961 cttctgcatg gaattggata ccataaaaat tacgtgttgt gtcttggata gaagcaatcg
    25021 gacaatcttt gcttgttccg actgtttcaa agccttcagg aactttagtt accaagtcac
    25081 catggctcat ccatactgtt tgttgttttg gtgtttcttt aaacaagaca gcttgatcgc
    25141 ttgttacttc taacaaggct ttcccatatt cgcggttttt agcaggctct acggaaccgc
    25201 caagtttgta cgtgatcaat tgcataccat agcaaatccc taatacagga atacctaaat
    25261 tgaagatctc aggatcgatc ccaaatgcat tctcatcata tacactgttt ggtccgccag
    25321 aaagaatgat tccctttgga ttcatcgctt ttacttcttc tgcagtaatg cggtggctca
    25381 ataattcgga aaagactcca agatcacgaa tacgtcttgt gatcaattgg ttatactgac
    25441 taccgtagtc taatacgata atcttttcaa cgttcgtcat atcggcaacg tttgtcaaat
    25501 ttattacccc tatcccttta aattttatct caaaatagtc aaactatttt aaaatgctaa
    25561 tattttcgca tgaaaatcga atcgatgata tgattttcag ttttatggag aattatatcg
    25621 gctcttcctc gtgtaggcaa gatatattcc tgtaaatttt tcaaattcac atttttccat
    25681 acatcttttg ccattttaaa ggcttcttca cgatctccga tagcaaaacg ataataataa
    25741 ttctctggat tttggaaagc cgtatccagt aacgcaccaa aacgatccaa ataccatttt
    25801 tcgatcagca cgggatcggc atcgacatag acagaaaaat caaaaaagtc gctgacgtag
    25861 atttgctgat tcgcaggtaa ttgaagcgta ttgatcccct caacgatcaa gatatcaggc
    25921 tgctggatca attcgtactt gtctggaatg atatcataca catcatgtga gtaaacaggt
    25981 acttttatct cttcctgacc agattttaca cggttcaaga aatcgatcag catctccata
    26041 tcataacttt caggaaatcc tttacggtcc atgattccac gctcttttaa tatacgattt
    26101 ggataaagaa atccgtcagt cgtgatcagc tgaacgtttc ttcgtttgaa ggtacgagac
    26161 aaaatcgtct gcagcagtct ggctgttgta ctttttccaa cggctacact tccggcgatc
    26221 ccgataataa aaggcggtac ttctacgtat ttatgaagaa ataaaccttt actcaagaac
    26281 aaagattcaa attctttcat ataaagataa atcagatgag caagaggtac atagatatct
    26341 cgaacatcct gcatggaaat gcggtcattc aaacttttga tattatctag ttcatcttgt
    26401 gtcaaaggtg cttgcccatt acgataaaat tctcgccatt cttctcttgc cacacggtag
    26461 tagttcattg gatcattcat attagcctcc tgcgttctcc catcaatgga actattttaa
    26521 cacaaaataa acgcaaaccc caccacttaa gagagattgc cgatcttttt gtataatctt
    26581 tataatagaa agaaacggag tcttattctt gacttgcgca cggatacata aaaggataga
    26641 ctgttgtcat gaaagaaatg agaaggatgg aagacatgac aaatcattac tattctgaac
    26701 gcccagatac ggcgcacgat tttgaacaat gggcttttga gttaaaaggc agaacctttc
    26761 aatttgtaac agattctggt gtattttcac gtgaaacagt ggattatggt tcacgtgtcc
    26821 tgattgatgc tttcgattgg gaagagttac ctgatgaagg aaagatctta gatgtgggat
    26881 gcgggtatgg accgattggg ttagctttgg catttgcgac acagcggttt gttgaaatgg
    26941 tcgacattaa tgaacgagcg gtaagtctag cgcaaggaaa cgcaaagcgt aaccaaatcg
    27001 aacatgttga tatccatcaa tcgaatatct atgaagcagt tcatgaagaa acctatgcag
    27061 ctatcgtaag caatccgccg atccgtgctg gaaaaaaagt tgtacatgaa attttgacag
    27121 gcgcatatcc tcggttgaag aagggcggta cactgacaat tgtgatccag aagaaacaag
    27181 gagcgccgag tgcgcaaaag aaaatggaag aaacatttgg taatgcagaa atcgtcacaa
    27241 aagataaagg atattatatc atcaaaagtg tgaaagaata actagctgaa aaatagtgga
    27301 gcgacgaaag agtggaactg ggcgtgcatg tacgggtacg tatcagttct ttttttgttg
    27361 agaagttttt aaaaacaaag aactattttt tcttcaaaaa gaaatagtag gaacagagtc
    27421 gttgtttttt acgataaaat aaataagata cagaacttgt atagaaggct gccaagtcgg
    27481 tagataaagg aggtttttat caaaaaacat actttccttt tttctctatt cttttcttgg
    27541 gggttttggt acactgatag ggaatttaga tagaagggag ccaataggat gaagctgacc
    27601 atcagagata tcgcagaaat ggcaggcgta tcagtaacaa ctgtctcaca gattttgaat
    27661 aacaaaggaa gcagatttag tgataagaca agaaaaaaag tgttgtcgat cgtgaatgaa
    27721 catcattata agcccgatta tttcgcttca aatgtgatca atcgacattc aaagaccatc
    27781 ggaatgatcg tccctgatgt cactgatttc ttcttctcca aactgatcga aggtgtagag
    27841 agctatttga atcctttggg ctatgtgatc atgttatgca attctcgtca tagccaagaa
    27901 aatgagatca agtatttaca agagctttcc caccgctcag tggacggaat cttgctggcc
    27961 acaccaaata ttttacctga gaaatatgca ttagacagcg gtttttatca aaaaatgcca
    28021 atcattttaa tcgatcgcgg attgaatcgt cgggataacg gacggcttat cgtaaaggaa
    28081 tatgagggcg cctatcaagc tgtttcgctg tttattgaaa atggccatac gaagatcggc
    28141 atgctgaagg aaaccactgg atactatcaa ttagaagaac gtttcaacgg atatcgtcat
    28201 gcgctgaaag atcatggcct gccttttaat gggaaatttg ttgaacatgg agagttgact
    28261 gtccaaggtg gatatactgc atcaaaaaaa ttactcaaac ataaagatat cacggctatt
    28321 ttttgcggga atgatgccat ggcgatcgga tgctatcagg cgatcgatga attgggcaaa
    28381 aaaatcccag aagatatctc agtcatagga ttcgatggat taaagctgtc agaatacatg
    28441 attccgcaat tgacgacagt gcagcagcca agttttgata ttggatttta tgctgcacgt
    28501 ttcctgatcg atacgatcga atttcctcaa agaaaagttc cgaacaaagt gttcgaaaca
    28561 aaattaatta ttcgtgagag cgtaaaagta ttgacaaagg gctaactcgg cggtatattg
    28621 cttatgtaag catttacaaa ggctagttag tgcttttttt atttttagta aaccagttta
    28681 ctaaagtggt ttacctttcc taaaaataat gtataatacc gaatgaagac aaggaggatc
    28741 aggcaatgcg aatggtggat ctgattgaaa aaaagaggga tggaaacgag ctgtcgaaag
    28801 aggaaatcga gtacatcgtc acgaactata cgaatggaaa gattccagat tatcaagtca
    28861 gtgcattatt gatggcaatt ttttatcaag acatgacaaa tgaagaaatc acgaacttaa
    28921 cattggcgat tgctaattct ggtgatgtca tcgatttgag ttctcttgaa ggaataaagg
    28981 tagataagca ttcgacaggt ggcgttggtg acacgaccac attgatttta gcccccctag
    29041 tagctagtgt cggagtgaca gtggctaaaa tgtctggacg cggtctaggt tacacaggtg
    29101 gtacactaga caagctagaa gcaattcccg gatttcagat cgagctttcg gatgaagaat
    29161 ttgtacgcat tgttaatgaa agtaaagtag cggtaattgg tcaatcagga aacttggcac
    29221 cggcggacaa aaaattgtat gccttgcgtg acgtcacagc gaccgttgat tctcttccgc
    29281 tgattgccag ttcgattatg agtaaaaaaa tcgcggcagg agcagatgca atcgttttgg
    29341 atgtgaccac tggagacggt gctttcatga agaacatcga agatgcaaga cgtctggcaa
    29401 agaccatgac gagcattggg aaactggcta accgagaaac agtggcggtt atctcagata
    29461 tgtcagaacc tcttggcgaa gctatcggaa atagtctaga agttgtcgag gcaatcgaaa
    29521 cattacaagg aaatggtcca gaagatctag tagaaatgtg ctacgcctta ggaagccaaa
    29581 tggttgttct tgctggcaaa gctaagacaa ccgatgaagc aagaacgttg cttcaagaag
    29641 ctctggaatc aggtaaagcg ttagcaaaat tcaaagaaat gatccaaaat caagggggag
    29701 acccagcgat cgtggaacat ccagaacgaa ttttgactgc acgctacaca atggagcttc
    29761 ctgctaaaca aagcggagtt gtgtcaaaaa tcgtggcaaa tgaattagga attgctgcaa
    29821 tgatgctagg tgctgggcgt aaaaccaaag aagaagatat tgatcacgct gttggattga
    29881 aactgcataa aaaaattggt gacactgtga caaaaggtga gtcactattg acgatctata
    29941 gtaacgacga agaaatcact tctgtcattg aattattata taaaaatatt gaaattggtg
    30001 aatcggcaat gaagccaacg ttgattcatg acatcatcac agaataaagg aaaaaagcgg
    30061 actttaccgt tttaaagaaa aggggaaaag aaatggaact aaaccgaatg atcgaccata
    30121 ctattttgaa agcagacgca tctaaagaag ctgtgatgca aattatcgaa gaagcaaaaa
    30181 aataccattt ttattctgtc tgcatcaatc cagcatgggt tgcgctagcg aaagaacaat
    30241 tacaaggtga gccagtagcc gtatgtacag taatcgggtt tcctctagga gcaaacacac
    30301 ccgagacaaa agcatttgaa acaacagatg ccatcaataa cggtgcagat gaagtcgata
    30361 tggtcatcaa tatcggtgct ttgaaatcaa aggatgatca acaagtccaa aaagatatcg
    30421 aagcagttgt tgaagcagca aaagatcgtg cgcttgtcaa agttattatt gaaacatcgt
    30481 tattagatag agaagaaatc atccgagctt gcgaaatagc aaaagctgca ggcgctgatt
    30541 ttgtcaaaac atcaactggt ttctcaacag gcggagcaaa ggtagaggat gtccgtttga
    30601 tgcgtgaaac tgtaggacca gaaatgggtg tcaaagcttc cggcggtatc cataacgaag
    30661 aagaagcaat ggcaatgatc gaagctggtg ctacaagaat cggaacaagc gcaggagtag
    30721 caatcgtatc tggttcaact ggtgaaggct attaattttt tcaaaggaga agctcatggc
    30781 agaactcaaa caagaatgga tcaacacagc tattgaagcg ttagataaag cctatgttcc
    30841 ttattcccat tttccggtag gcgcttgtct cgtaacggaa tcaggcaaga tttatcaagg
    30901 catcaacatt gagaatgcat catttggatt aacgaattgt gccgagcgca cagctttttt
    30961 caaagcagta tctgaaggag aaaaaacatt tacgcatcta gtcgtagcgg ggcacacccc
    31021 cgatcctatc tctccttgtg gtgcatgtcg acaagtaatg gcagaattct gttcccctga
    31081 tatgccggtt acgctagtag gagacaatgg tgtgacgaag gcaacgaccg ttcgtgcact
    31141 gctgccttat gcatttactg aaaaagatct ataactcatg ttcattcagt cagctgactg
    31201 ttgaaaaata aaacaattat tttaggaggc tttacagaaa tgaaaaaagc aaaattattt
    31261 ggtttaggtg ctgtcgcact agcagcaggg ttatttttag gtgcatgcgg caacaacggc
    31321 tctactgatt catccggtgg caaaagctca tcagacacaa caactgcagc attgatcaca
    31381 gacacaggtg gtgtagacga ccgttcattc aaccagtcag cttgggaagg actagaaaaa
    31441 tgggggaaag atcaaggact ttcacgagga aatgatggct tccaatattt ccaatcttca
    31501 aatgaatcag attacatccc aaatattgac caagcattga atgctggatt caaaacgatt
    31561 tttggtattg gttataaact aaaaccagcg atccaagaac aagcaacaaa caatacaggt
    31621 acgaactttg ttattatcga tgatgtcatc gatggattag ataacgttgt atctgcaact
    31681 ttcaaagaca acgaagcttc ttatcttgca ggtgttgcag cagcttatac gactgaaaca
    31741 aacgtagtcg gctttatcgg cggtgtaaaa ggtgaagtaa tcgatcgttt tgatgctgga
    31801 ttcaaagccg gtgttgatgc aggtgcgaaa gaattaggaa aagaaatcaa agtattgaat
    31861 caatatgctg gtgacttctc tgctccagat aaaggacgtt caattgctca aggtatgtat
    31921 gcacaaaacg cagatatcat cttccatgct tcaggcggta caggtaacgg tgtattccaa
    31981 gaagcaaaat cattgaacga atcaggcgac aaaaaagttt gggttatcgg tgttgaccgc
    32041 gaccaatcag acgaaggcga atacacatta aacggcgaaa agaaaaactt cacattgaca
    32101 tctacactga aagcagttgg aacagtagta gaagatttgg cacaaaaatc agcggacggt
    32161 aaattccctg gcggcgaaca cactgtttat ggattgaaag aagacggtgt tggtctaaca
    32221 gaaggacaac tttctgacga agcgaaaaaa gcagttgatg aagcaaaaga aaaaatcatt
    32281 tcaggtgacg taaaagttcc agaaactcct gaagaaaact aaaaccattt ctatagcctt
    32341 gttagacaca tgtttgacaa ggctatggtt tgattagaac aagaattgtt catttatcca
    32401 agctgccttg tgacagtttg gataagggaa caactccctg aagtaatgtt tgtttcaaaa
    32461 gaagaacgct cactaagcgt gaatcttagt caatcgttgc cctagataga aatcgttagg
    32521 atgtgaaaaa aaggtggttc aagaaaatat tgtcatagaa atgcagaata ttaccaaaga
    32581 atttggaaca ttcaaggcaa atgacaacat caatttacaa gtaaaggcag gagaaattca
    32641 tgcgttgctt ggagaaaacg gtgctggcaa atctacattg atgaacgtgc tttccggatt
    32701 attagagccg acatcaggga aaattttgat gcgtgggaaa gaagtaaaga tcacaagtcc
    32761 gaccaaagcc aaccaattag ggattgggat ggtccatcag cactttatgc ttgttgatgc
    32821 ctttactgta acagaaaaca tcgtgttggg aagcgagcct agtcgcgcag ggatgcttga
    32881 ccataaaaaa gcacgaaaag agatccaaaa agtttctgaa cagtatggat tgtcagtcaa
    32941 cccagatgct tacgttcgtg atatttcagt tggaatggaa caacgggtag aaattttaaa
    33001 aacactttac cgaggagcag atgtactgat ttttgatgag ccgacagctg tattgacccc
    33061 tcaagaaatt gatgaattaa tcgtgatcat gaaggaatta gtcaaagaag gcaagtcgat
    33121 cattttgatt acgcataagt tagatgaaat caaagcagta gctgaccgct gtacagttat
    33181 ccgccgtgga aaaggaatcg gtacagtcaa cgttaaagac gtaacctcac aacaattagc
    33241 cgatatgatg gttggaagaa cggtttcatt caaaacgatg aaaaaagaag cgaagcctca
    33301 agaagtcgtt ttgtctattg aaaatctagt ggtgaaagaa aatcgtggat tagaagccgt
    33361 gaaaaacttg aacttagagg ttcgtgctgg cgaagtactt ggtatcgctg gaatcgatgg
    33421 aaacgggcag tcggagttga tccaagcttt gactggtttg cgaaaggcag aaagcggaca
    33481 tatcaagcta aaaggggaag acatcactaa taaaaaaccc cgaaaaatca ctgaacatgg
    33541 tgtaggacac gtgccagaag accgtcataa atacgggtta gtcctagata tgacattatc
    33601 tgaaaatatc gcactacaaa cctatcatca aaaaccttac agtaaaaacg gcatgctgaa
    33661 ttattcagta atgaatgaac atgccagaga attgatcgaa gaatatgatg ttcgaacaac
    33721 gaatgaactt gttcccgcaa aagctttatc aggcggaaat cagcaaaaag caattatcgc
    33781 tcgtgaagtc gaccgagatc ctgatctgtt gattgttgca aatccaactc gtggactgga
    33841 tgtaggtgcg atcgaattta ttcataaacg tctgatcgaa caaagggaca aatacaaagc
    33901 agtgttactg atcagtttcg aattagaaga aattttaaat gtttcggatc gtattgctgt
    33961 tatccatgaa ggagaaattg tcggtatcgt tgatccgaaa gaaacatctg aaaatgaatt
    34021 aggtctattg atggcgggct ataccttaga agaagcacga aaagagttag aaaagggggc
    34081 tggcgcacat gaatgatcgc agcgaaaaat tccgtaattt attagtgcct gtactttcag
    34141 ttgttttagg attgatctta ggcgcgatat tgatggctgc ttttggtttt cagcccatcc
    34201 aaggttattc ttctatgcta gatgcagccc ttggttcgca aagagggata ggtgaaacgt
    34261 taaggcaagc aacgccgttg atttttacag cattaggttt ttctgtagct aactcagctg
    34321 ggtttttcaa tattgggctt tctggacaag cactttgcgg gtggatcgtc agtgtctggg
    34381 tggcacttgc gtttccagat ctgccaaaag ttgttttgct tccgttatgc gtgatcttag
    34441 gtgccttagc tggtgcgatg gcagcggctg ttccaggttt acttcgagca ttttttggaa
    34501 caagtgaagt gatcgtaaca atcatgatga actatatctt attatacgta agcacatttg
    34561 ctttacatga agtgatgcct gaaagctatc gctcaagttt ggactcttcc aatatgatca
    34621 gtcaaaatgc ctcactgcgg ttaccatggt taacacaagc ttttggcggc tctcgcgtaa
    34681 actcaggatt atttttagca atcatcgcgc ttattttcgt ttggctgctg atgaagaaaa
    34741 cgactttagg atttgaaatc cgttctgttg gattgaatcc ttttgcttct gagtatgcag
    34801 gaatgagtag taaacgtacg atcgttttgt cgatggtcat ttctggcgct ttggcagggc
    34861 ttggcggtgt ggttgaagga ttaggaacgt atcaaaactt ctttgttcaa acgacttcgc
    34921 tatctattgg atttgacgga atggctgttt ccttgcttgg ttctggatca gcaatcggta
    34981 ttcttttatc agcgatcttg ttcagtattt tgaagatcgg tggacttggc atgcagacag
    35041 gagcaggtgt tccgtttgag atcgtcaatg tatcgattgc tttgattatc ttctttgtcg
    35101 ggatcaactt cctgattcgt ttcgtcatgg ctaaagtctt ccaagggaaa aaacaagaag
    35161 agatcgttgc gacaatagaa tcgaaaccaa cgaatcaaaa ccatgaaggg ggcgaactat
    35221 aatgtcgact atcgaattaa ttgccttgat ccttacttct acactggttt attcaacacc
    35281 gctaattcta acgtcactag gcggaacttt ttctgaacga agcgggatcg taaacgtagg
    35341 gctagaggga atcatggtca tgggtgcttt tagttccatc gttttcaact tgacgatgag
    35401 tccatcactt ggttctatga caccatggat cgctatttta gtgggtggcg tcgtaggtat
    35461 cctattttct ctgattcacg cagtagcaac agtcagtttg cgtgctgacc atattatcag
    35521 cgggacagta attaatctga tggcacctgc tttaggtgtt ttcttgatca aagcatggta
    35581 tggtaaaggt caaactgata acatcacgca gaatctgggg tatttttctt tcccaggatt
    35641 agcagatatt ccggtcattg gaccaatttt ctttaaaaat acattcttac ctgcttattg
    35701 tgctattttg attgctgtcc tagcttgggt gatcatcttc aagacgaaat tcggcttgcg
    35761 cctccgttca gttggtgaaa atcctcaagc tgccgacaca ttaggtatca atgtatatgc
    35821 tatgcgttat tcaggcgtac tgatttctgg cttgttaggc ggtatgggcg gtgctgtttt
    35881 tgctcagtcg atttccggta acttttcagc tggtacgatc gttggacaag ggttcatctc
    35941 catggctgct atgatctttg gtaagtggaa tcctttaggg gcaatgggtg cctcattgtt
    36001 ctttggtttt gctcaaagct tgagtatcat tggcgcacaa ttaccagtta tttcttcgat
    36061 tccgccagta ttgctgcaaa ttgctccata tttgctgaca atcattgtgc tggttgtttt
    36121 cttagggaaa gcttctggtc caaaagcaaa cgggaagaac tatatcaaat caaaataatc
    36181 ttttagcgaa taaaaagggt gggttacggg aagtgttttt cgtctcgccc tttttgtttt
    36241 aaaggcaata aaaataaaaa gaaagaagga ataatcatgt ttaaacgcgt acatctgatc
    36301 gtcatggatt cagtaggaat tggagaagca ccagatgccg ataagttcgg tgatgttggt
    36361 tctgatacat taggacacat tgcgaaagaa gcaggattga acgttccaca tttagagcag
    36421 cttggtttag gaacgatccg tcctcttgaa ggtgtggaat cagtgaaaga tcatcaaggc
    36481 tatgcgacga aattagaaga agtttctgta gggaaagata cgatgacagg ccactgggaa
    36541 atcatgggat tgaatatcaa aactccattt cgtgtgtttc ctaatggatt ccctgatgat
    36601 ctgatcaaac aaatcgaaga attttctggc cgtaaagtcg tatgtaacaa accttatagc
    36661 ggaacagctg ttattgacga ttacggtgaa caccaaatga aaacaggcga tttaattgta
    36721 tatacttctg ccgatcctgt ccttcagatc gcggcacatg aagaaatcat tcctttagaa
    36781 gaattatatc ggatttgcca attcgttcgt gatataacaa aagatgatcc gtatatgatt
    36841 ggccgaatca ttgcacgtcc gtacgtgggt gaaccaggag acttcacacg aacaagcaat
    36901 cgccatgatt atgcgttgaa tccattcgga cacacagtcc ttgattcttt gaaagaagca
    36961 ggaaaggacg tgattgctgt tggaaagatc aacgatattt tcaacggaca aggaatcact
    37021 gaatctgtcc gcacgaaaag caatatggat ggcgttgacc agctgctgaa agttatgaaa
    37081 aacgattttt caggaatcag ctttaccaat ttagtagatt ttgatgcatt atacggtcat
    37141 cgtcgggatg tagtcggcta tgcgcatgcg attgaagaat ttgacttacg aattccagaa
    37201 ttgcttgaag cgatggaaga agacgacttg ctaatgatta cagccgatca cggaaacgat
    37261 ccgacgttta ctggtaccga tcatacgcga gaatatgtac cgttattggt ttacagtaaa
    37321 aaaatgaaag aacaaggggc attgcctcaa ggatattatt cagatatttc agcaacgatt
    37381 gctgagaact ttagtgtttc ttcgactgaa aatggcgaaa gcttcttgaa attattaaaa
    37441 taatcttttt aaataggaga aagcaaatga ccaagttaag cgagatgtta caagaaacga
    37501 cccagtttat ccttgataaa ggagtaaaag aaattgattt tggtttgatt ctaggttcag
    37561 gattaggtga attagcagat gaaatcgaag atgctgtaat gatttcttat gatgagatcc
    37621 cgttctttcc tgtttcgaca gtagttgggc atgcaggaaa gctagtttat gggtctctgg
    37681 caggcaagaa agtgttagcc atgcaaggga gattccacta ctatgaaggt cattccatgc
    37741 aaacagtgac ctatccagta cgtgtgatgg ccggactagg ggcccattca gtcattgtga
    37801 ctaatgcatg tggtggtgtc aacgaatcat ttgtaccagg agatttgatg ctgattaccg
    37861 atcatatcaa ttttactggt gaaaatcctt tgatcggtcc gaatgaagat gcaatgggcc
    37921 ctagatttcc agatatgagt caagcttata cgcctgacta tcaagcaaca gcaaaagcag
    37981 cagcagaaaa actaggtttg gatcttaaag aaggcgtata tatgggctat tctggaccaa
    38041 cttatgaaac gcctgcggag atccgaatgt ctcggacaat aggagccgat gcagtaggga
    38101 tgtcgactgt tccagaagtc atcgtagcag ctcacagcgg attaaaagtg ttaggaatct
    38161 cttgtattac caacttagca gcaggtatgc aagcgaatct gagccatgaa gaagttgtag
    38221 aaacaactca gagagtcaaa caatctttta aagcattggt taaagaaaca ttgacattat
    38281 tgtaatagga ggaacaataa aatgagtgtg catattgaag cgaaagaagg cgagatcgcc
    38341 gataagattt tacttccggg agatcctttg cgagctaaat atattgcgga gacttttttg
    38401 gaagatccag tttgttacaa tcaggtacgc ggtatgttag gctttaccgg caaatataaa
    38461 ggagaacgta tttctgttca aggaacagga atgggaatgc catcagccac catctatgcc
    38521 catgaattga tccagtcgta tggtgtaaag aaattgattc gagtaggtac atgcggtgca
    38581 ttgtcaaaag acgtccatgt tcgtgattta gtactagcac aaggtgcagc gaccagttct
    38641 tcgatgatcg aaaaaaattt ccaagccttt cattttcctc caatcagtga tttcaatcta
    38701 ttactgaaag catatgagat agctaaagaa aagggctata cggttcatgt aggaaatgtt
    38761 ctttcggaag attctttcta caaagatgat ttgacagaga cgttccaatt agctgaactt
    38821 ggcgttttag gagtggaaat ggaagcagcg gctctttatt acttaggcgc gaaataccat
    38881 gtgcagacat taagtttgat gaccgttagc gaccatttga tcaccggtga agaaacaaca
    38941 gctgcagaac gtcaatctac gttcaatgaa atgatcgaag taggattgga aacagcgata
    39001 gcagaataag aaggaaatga aaaagctgcc ctgcattaag taataagaac atccaagcaa
    39061 aaatagctcc tcatgttttt gacttggctg gacttattat tgcaaatgta agcttttgaa
    39121 caccgtttac caagaggttg tgaatctgcc gtttaactct gagtcacaag gaacaatttc
    39181 aaaaaacagc ttttcatgtt tgatgaatat tgtgacttgt gaccgagaag ttggcaggag
    39241 aaaaccgttt atacgaaaaa agggactgtg acaaatcgtg tcacagtccc ttttttatag
    39301 tgttttttat aggtagtatt ttttagcaac tgttaagtca tcatttaatt cataaacaag
    39361 tggttgacct gttggaattt caagatccat gatgtcttcg tcagagatac cttcgatatg
    39421 tttagctagg gcgcgtaatg agttaccatg tgcagctact aaaacagttt tgttgtctag
    39481 taatgctgga gcaatttcat cttgccagaa tggcaaagcg cgttctaatg tcactttcaa
    39541 gttttctcca ccaggaatat cgcgtttgtc taacattgcg taacgacggt catttgctgc
    39601 agaaccttcg tcagtttctt ccattaatgg aggaagagta tcgtaagaac gacgccagat
    39661 gtgcacttgt tcgtcgccgt atttttcagc tgtttctttt ttgttcaaac cttgtaattt
    39721 accatagtga cgttcgttta agcgccatga tttgatttgt ggtacccaaa gttgatctga
    39781 atattctaag atcaagttac atgttttgat tgcacgagtt aaaacagaag tgtaagcaac
    39841 atcaaattcg attccagctt ctttgatttt gcgtccgcct tcttttgctt cttcgattcc
    39901 ttctggtgct agatttacat cagcccaacc agtaaattgg ttcaatgcat tccattcact
    39961 aagaccgtga cgagaaaaaa ctaattttgg catgtttagc tctcctttta agataggttt
    40021 atatttctga aattttcagt tctgttttat tgtacaattt tttggaagag atttccatcg
    40081 aaaaattaga taagattcta tgagaaaaca agtagagaat ataaaaaaac gaacagtgcc
    40141 cacgcaactg ttcgttttta ggtattagat gcataattgc tcgatttctt tttcaggtaa
    40201 attgatatat ttataacatg ttccaactga aacaccgcat tttgaagaaa taaattggat
    40261 cgtttctttt ttttcataat agagacgtcg gatttttttg atcgtttttg catcgatttt
    40321 tggtcttccg ccgatttttc cttttttacg agcttcatct aatccaacta atgtacgttc
    40381 tttgatcaat gcgcactcca tgtttgctag gttttccatt aattggaaat agatttttcc
    40441 catttcgcgc gtatcgattc cttcatcaag actaatcaag tgcagcccgc gatctttgaa
    40501 taattgcgtg agttctgtta attgccgcgt agatttgcct aatcgatgaa gttggcaaat
    40561 gactagtgca tcgccttgtt gcatgtcagc gatcactgac tccaaatgaa cagcagtaga
    40621 atcattttgt tccacttcat atgtctcatg gaaaatttct tgacaaccaa agtcagataa
    40681 ttgatcaacc tgagttgtta aatcaacgtc atttatggtt gtgcgtgcat aaccaataat
    40741 tttcatggtg attcctttct agcagtgatt ttctaactgg atataacagt aaaaatgtag
    40801 cataaagtac gtcaaaaaga tagttttttc gcaaattttc cgctgtcttt ttttattgga
    40861 tgatcaagca gtttttcttt atttacgacg gattgcgtca agaatctcaa cgcctttttc
    40921 tgagccgaca actactttag aaaccatgtt taggaaaagc ccatgttcta ctaccccaac
    40981 aagttcatct aaataggtag ctaagctttc tggctgttcg atgacttcta gatgcagatc
    41041 aatgatgtaa tgaccaccat ctgtggttaa gacttctccg ttttcgtctg tacgcaagac
    41101 gggttggaat cttttttctt caaaaatatg aagtagctgt tgggagccat aagggatcac
    41161 ttcaactggg agtgggaact tcccaagttt atcgactaat ttagaagaat caacgatcca
    41221 aatcgtttct tttgagtacg tagcgactat tttctcgaaa agcaaagcag cgccgccgcc
    41281 tttgatccct tgaaaatcag cactgatttc atcagcaccg tctattgtca aatcgactac
    41341 ggggacttca tcaatactct ttaacggtat tcctaatttt tccgcttgtt cttttgtcgc
    41401 atttgaagta gtaactcctg tgatacgtaa accttcttca cgcatacggc gaccaatctc
    41461 ttctaccata taataggcgg ttgaaccggt cccgagacct acgatcatcc cgtcctttac
    41521 gaatttcgcg gcttcaatgc cagctaattg ttttaaattc atctttgcgt ccaccttttt
    41581 ttagtttgag catcgtgctt tcctcactat tttagcgtga tttacggtaa aaagatacca
    41641 ttctttttta ttccaataaa gctttttcaa aaaaaattgc atctcttgtt gacatgtttt
    41701 ttcattcgtg atattctaac aaaggtgctt tatctacagg tttctgtgaa gaaacgtgct
    41761 gactgtttat caaagcatat ttgataagga tgcagacatt gcatttattt tttatcacaa
    41821 aaaaagaacc acctggatgt gtggaactag acgcaaatcg tgggaaggag gaaacaagga
    41881 atgcctacaa ttaaccaatt agtacgtaaa cctcgtaaat caaaggtgga aaaatctaat
    41941 tcacctgctt tgaacaaagg atataacagc tttaagaaaa ctcaaactaa cgtaaactca
    42001 cctcaaaaac gtggggtagc aactcgtgtg ggtacaatga cacctaaaaa accgaactca
    42061 gctttacgta aatatgcacg tgttcgtttg tcaaacttaa ttgaagttac tgcttatatc
    42121 ccagggattg gtcataactt acaagaacac agtgttgtat tattacgcgg tggtcgtgta
    42181 aaagacttac caggggtacg ttaccatatc gttcgcggtg ctttagatac tgctggtgtt
    42241 aacgaccgta aacaaagccg ttctaaatac ggaactaaaa aacctaaagc ttaattttaa
    42301 ttattaaaca aatgaaactt gcttctacta tatagaagta attactatga acaatatttc
    42361 ggaaggagga gttacggatg ccacgtaaag gtcctgttgc aaaacgtgat gttttaccag
    42421 atcctattta taactcaaaa ttagtaactc gcttgatcaa ccgtgtaatg gttgacggaa
    42481 aacgcgggat tgcagctaac attatctata atgcctttga cttgatcaaa gaatctacag
    42541 gtaacgatcc attagaagtg tttgaacaag caatgaaaaa cgttcaacct gttcttgaag
    42601 ttaaagcacg tcgtgttggg ggttcaaact accaagtacc agttgaagtt cgccctgaac
    42661 gccgcgttac tctaggtctt cgttgggtag taaactacgc tcgcttgcgc ggtgaacaca
    42721 caatggaaga acgcttagca aaagaaatca tggatgctgc aaacaacaca ggtgcttctg
    42781 ttaaaaaacg tgaagacact cataaaatgg ctgatgccaa ccgtgcgttt gctcactatc
    42841 gctggtaaga ttctctctgt ttggtcggct tttataagtc gacctcagat agtgtcctta
    42901 tttttagcaa ctagatagta aagagaggag aaacaaggag aatgaccaga gaattttctt
    42961 tacaaaacac tcgtaatatc ggtatcatgg cccacatcga tgctggtaaa acgactgcta
    43021 ctgaacgtat cttgtactat actggtaaaa tccataaaat tggtgaaact catgaaggag
    43081 cttcacaaat ggactggatg gaacaagaac aagaacgtgg tattacgatc acttctgctg
    43141 ctactacagc acaatggaag ggtcaccgaa tcaacatcat cgacacacca ggacacgtag
    43201 acttcacagt tgaagttgaa cgttcattgc gtgtacttga tggtgctgta actgttcttg
    43261 atgcacaatc aggtgttgaa cctcaaactg aaacagtttg gcgtcaagca acaacttatg
    43321 gtgtacctcg tatcgtattt gcaaacaaaa tggacaagat cggtgctgac ttcttatatt
    43381 cagtatcaac tttacatgac cgtttgcaag caaacgctca cccaatccaa ttaccaattg
    43441 gtgcggaaga cgacttcaca ggaattatcg accttgtaac aatgaaggct gaaatgtata
    43501 caaacgatct tggaacagag atcgaagaaa cagaaattcc tgaagaatac cgcgaattag
    43561 ctgaagaatg gcgcgaaaaa ttggttgaag ctgtagctga aactgatgaa gaacttactt
    43621 tgaaatactt agaaggtgaa gaaatcactg aagctgagtt aaaagaaggt atccgccgcg
    43681 caacagttaa cgtagaattc tacccagtac tatgtggttc agcatttaag aacaaagggg
    43741 ttcaattact attggacgct gttcttgatt acttgccatc accgttagat atcccagcta
    43801 tcaaagggat tgaccctaaa actgatgaag aagtagaacg tcctgcagac gacagcgctc
    43861 ctttctcagc tttagcattt aaagttatga ctgacccatt cgtaggtcgt ttaactttct
    43921 tccgtgtgta ctctggtgtt ttacaatcag gttcatacgt acaaaacgca acaaaaggca
    43981 aacgtgaacg tgttggtcgt atcctacaga tgcatgccaa ctctcgttca gaaatctctg
    44041 aagtttacgc tggagatatc gctgctgctg ttggtttgaa agacacaact actggggaca
    44101 cactatgtga tgaaaagagt ctagttattc ttgaatccat ggaattccca gaaccagtta
    44161 tccaagtcgc tattgaacct aaatcaaaag ctgaccaaga taaaatgggt gtggctttac
    44221 aaaaactatc tgaagaagat cctactttcc gtgctgaaac aaacgtggaa acaggcgaaa
    44281 caatcatcgc tggtatgggt gaacttcact tagatatcat cgttgaccgt atgcgtcgtg
    44341 aattcaaagt tgaagctaac gtaggtgcgc ctcaagtatc ttaccgtgaa actttccgtg
    44401 ctggcactca agccgaaggt aagtttgtac gtcagtctgg tggtaaaggt caatacggtc
    44461 acgtatggat tgaatttaca ccaaatgaag aaggtgctgg tttcgaattt gaaaatgcga
    44521 tcgtcggtgg ggttgttcct cgtgaataca ttccagctgt tgaaactggt ttgaaagatg
    44581 ctatggaaaa tggtgtctta gctggctatc cattagtaga tatcaaagct aaactttacg
    44641 atggttcata ccatgatgtc gattcaaatg aaactgcctt ccgtgttgct gcttctatgg
    44701 cattacgtgc agcagctaag aaagctaatc cagtaatcct tgaaccaatc atggctgtag
    44761 aagttgttat ccctgaagat tatttaggtg atgttatggg tcacgtaact gctcgtcgtg
    44821 gacgtgttga aggtatggaa gctcgcgctg gcggccaaca agttgttcgt gcgatggttc
    44881 cacttgctga aatgtttggt tatgctacaa ctcttcgttc tgctactcaa ggtcgtggta
    44941 catttacaat gacatttgac cactacgaag atgtaccaaa atcagtacaa gaagaaatca
    45001 ttaagaaaaa cggcggaaaa gctgaataat ttcttaaaac cggatagtcc tgcaaagaga
    45061 ttatccaaag agactatatt tttaatatag tttcgtgtaa aataattatc gatgatatgg
    45121 gcatgtggtg taccttgtgt acatcatata cctatcagac aaataaaaaa tatattgtat
    45181 ttttaggagg acattttaaa atggcaaaag aaaaatttga ccgttctaaa ccacacgtta
    45241 acattggtac tatcggacac gttgaccatg gtaaaactac attaacagct gcaatcacaa
    45301 ctgtactatc taagaaaaac ggcggccaag ctatggctta cgatcaaatc gatggtgctc
    45361 cagaagaacg cgaacgcgga atcacaatct caacagctca cgttgagtat gaaacagata
    45421 cacgccacta cgctcacgtt gactgcccag gacacgcgga ttacgttaaa aacatgatca
    45481 ctggtgctgc tcaaatggac ggagctatct tggtagtttc tgctgctgac ggcccaatgc
    45541 ctcaaactcg tgaacacatc ctattgtctc gtcaagttgg tgttccttac atcgttgtat
    45601 tcttgaacaa agtagacatg gttgatgacg aagaattact agaattagtt gaaatggaag
    45661 ttcgtgacct attaacagaa tacgaattcc ctggtgacga tgttcctgta gttgctggat
    45721 cagctttgaa agctctagaa ggcgacgctt catacgaaga aaaaattctt gaattaatgg
    45781 ctgcagttga cgaatacatc ccaactccag aacgtgacaa cgacaaacca ttcatgatgc
    45841 cagttgaaga cgtgttctca attactggac gtggtactgt tgctacaggt cgtgttgaac
    45901 gtggacaagt tcgcgttggt gacgaagttg aagttgttgg tattgctgaa gaaacttcaa
    45961 aaacaacagt tactggtgtt gaaatgttcc gtaaattgtt agactacgct gaagctggag
    46021 acaacattgg tgctttacta cgtggtgttg cacgtgaaga catccaacgt ggacaagttt
    46081 tagctaaacc aggtacaatc acacctcata caaaattctc tgcagaagta tacgtgttga
    46141 caaaagaaga aggtggacgt catactccat tcttcactaa ctaccgtcca caattctact
    46201 tccgtacaac tgacgtaaca ggtgttgttg aattaccaga aggaactgaa atggttatgc
    46261 ctggcgacaa cgtaacaatg gaagttgaat taatccaccc aatcgctatc gaaaacggta
    46321 ctaaattctc aatccgtgaa ggcggacgta cagttggtgc cggtgtcgtt acagaaatca
    46381 aagcttaatt cacttaagtt ttaaagtaaa gcaacattta ttcggacgta atcgctcgga
    46441 acgaaggtct taggatcttt gttccgagct tttttattta ttgcaggatc aggaaaaaag
    46501 acaggagtat tataaataga agaaacacga aataaaagag tcagtatttt ctaaatgaaa
    46561 ctttatgaaa acaaaatgtt ttttacaaga aaaagccttg ctttgtgagt ttatatatat
    46621 tataatgaca aaggtgcgtt tactttagtg aattgcacag acgtaatcag aatgatttcg
    46681 tcggctaaga aacgagaggt tgcgacacgc ccggacgctt tgccacgaac gagcgtgacg
    46741 gaaattttcg tggagctatg tctacttttc aaaataggcg aaggagggaa caagatggca
    46801 aaacaaaaaa ttcgtatccg tttaaaagcg tatgaacacc gtattttaga tcaatcagcg
    46861 gataaaatcg tggaaactgc aaaaagaact ggagctagcg tgtctggtcc aattccatta
    46921 ccaactgaac gcagtcttta cacaatcatc cgtgcgactc ataaatacaa agattcacgc
    46981 gaacaattcg aaatgcgtac acacaaacgt cttatcgaca ttgtgaaccc aacaccaaaa
    47041 actgttgatg ctttgatgaa gctagactta ccatctggtg taaacatcga aatcaaatta
    47101 taaaactaaa acaaaaataa tggaggtgta ctcatgacca aaggaatctt agggaaaaaa
    47161 gtgggaatga cacaaatctt cactgaatct ggtgaattaa ttccagtaac tgttgtagaa
    47221 gctactccaa acgtagtact acaagtgaaa acaatggaaa cggatggcta cgaagctatt
    47281 caagttggtt accaagatat gcgtgaagtt ttatcaaaca aacctgcgaa aggtcatgtt
    47341 gcaaaagcaa acacggctcc taagcgcttc attcgtgaat tcaaaaatgt tgagctagga
    47401 gaatatgaag taggaaaaga aattacagta gatgttttcc aagcaggaga cattattgat
    47461 gtaacaggta ctacgaaagg taaaggattc caaggggtta tcaaacgcca cggacaaagc
    47521 cgcggaccaa tggctcacgg ttctcgttac catcgtcgtc ctgggtcaat gggtccagtt
    47581 gcacctaacc gtgtatttaa aaacaaacgt cttgctggcc gtatgggtgg caaccgcgta
    47641 actatccaaa acttggaagt tgtacgtgtc gatgcagaaa gaaatgttat cttgatcaaa
    47701 ggtaatgttc ctggagctaa aaaatcttta attactatca aatcagctgt gaaagctaaa
    47761 taattgtagg aagaaaggag gaactaagga atgccgaatg tagcattatt caaacaagat
    47821 ggaagccaaa acggtgaaat cacacttaac gaagaaatct tcggaattga acctaatgaa
    47881 agtgttgttt acgatgcaat cgtaatgcaa cgtgcgtcat taagacaagg aacacacgcg
    47941 gttaaaaacc gtagcgctgt tcgcggcggc ggacgtaaac catggcgtca aaaaggaaca
    48001 ggtcgtgcac gtcaaggatc tatccgctca ccacaatggc gtggaggtgg cgtagtcttt
    48061 ggaccaacac cacgttctta cagctacaaa cttcctaaaa aagttcgtcg tttagcaatg
    48121 aaatctgtat tgtcagaaaa agttgctgaa aacaacttgg tagcaatcga aggcttgaac
    48181 ttcgacgcac caaaaacaaa agaattcaaa caagttcttg ctaacttatc tatcgactct
    48241 aaagtattgg ttgttctaga aaaaggtaac gactttgctg ctttatcagc acgtaactta
    48301 ccaaacgttt ctgtagtaac ttctgataat gtgagtgtgc tagacgttgt atcaaataca
    48361 aaagtgttag caacacaaac tgctcttact caaattgagg aggtgcttgc ataatgaact
    48421 tactagacgt aatcaaacgc ccagtgatca ctgaaaaatc aatgcttgcc atggatgaca
    48481 agaaatacac ttttgaagtg gacactcgcg caaacaaaac tttagtaaaa caagcggtag
    48541 aagctgcttt tgacgttaaa gtcaaaaacg tgaacatcgt gaacgtacgt gcgaaattca
    48601 aacgtatggg caaatatgca ggatatacaa aaaaacgtcg caaagcgatc gttacattga
    48661 ctgaagattc aaaagaaatc caattattcg aagctgctga ataagcacta atagataact
    48721 cattaaatta ggagggaaaa acgtggcgat taaaaagtac aaacctacct caaatggtcg
    48781 tcgtaacatg acaggttctg attttgctga aatcacaaca tcaacacctg aaaaatcatt
    48841 gttacaacca ttgaaaaacc atgctggacg taacaacaac ggccgcatca ctgtacgtca
    48901 tcaaggtggc ggacacaaac gccaatatcg cgtgatcgac ttcaaacgta acaaagataa
    48961 cgttgttgca actgttcaaa cgatcgaata tgatccaaac cgttcagcta acatcgcgtt
    49021 agtacactat gaagatggag tgaaagctta catcttagca cctaaaggac tagaagtggg
    49081 tatgaaactt gtttcaggtc cagaagcaga tatcaaagtc ggaaatgctc ttccattaga
    49141 aaacattcca gttggtactg ttatccacaa cattgaaatg aaacctggta aaggtggaca
    49201 attgatccgt tctgctggta caagtgctca agtacttggt aaagaaggca aatacgtatt
    49261 gatccgcttg aactctggtg aagttcgtat gatcttagct gcatgccgtg ctacaatcgg
    49321 ttctgtaggt aacgaacaac acgaattaat caacatcggt aaagctggac gctctcgttg
    49381 gatgcgtaaa cgcccaactg tacgtggtag cgtaatgaac cctaatgatc acccacacgg
    49441 tggtggtgaa ggtaaagctc ctatcggacg taaagcacca gtttctcctt ggggtcaacc
    49501 agctcttggt tacaaaactc gtaacaaaaa agctaaatca gacaaactta ttgttcgtcg
    49561 tcgcaaaaat aaataattac tttgaccatg tgtcgcacat tttgagagga ggttcaccat
    49621 gggtcgtagt ttaaagaaag gaccttttgt cgatgagcat ttaatgaaaa aagttgaagc
    49681 tcaagcaggg gttgaaaaga aaaaagttat caaaacttgg tcacgccgtt caacagtttt
    49741 cccaagtttt gttggatata ccatcgcagt ttatgatgga cgtaaacatg taccagttta
    49801 catccaagaa gacatggtag gacacaaatt aggtgaattt gcacctacaa gaacttatcg
    49861 tggacatgct gctgacgata agaaaacgaa acgctaattt gaggggagga taaatccaaa
    49921 tggcagaaca aatcacatca gctaaagcaa ctgcaaaaac agttcgcact tcacctcgaa
    49981 aagcccgttt agtaattgac cttatcagag gtaaaagtgt cgcagatgca atttcaatct
    50041 tgaaattcac accaaacaaa tctgctggaa tcattgaaaa agtattgatg tcagcagttg
    50101 cgaatgcaga aaataacttt gacttagatg ttgaaaactt ggtagtaagc gaagcttttg
    50161 ttaacgaagg acctacaatg aaacgtttcc gtcctcgtgc aaaaggatca gcttctccaa
    50221 tcaacaaacg tacaagtcat atcacggtag tcgtatcaga aaaataagga gggataatca
    50281 gtgggtcaaa aagtacatcc aattggaatg cgtgtaggca tcatccgcga ctgggatgct
    50341 aaatggtatg ctgaaaaaga gtatgctgag ttcttacacg aagatttaag aatccgtaaa
    50401 tttatttcaa ctaaacttgc tgatgctgct gtatcaacag ttgaaatcga acgcgcaaca
    50461 ggtcgcgtaa acatttcaat tcacacagct aaaccaggta tggttattgg taaaggcggt
    50521 tctgaagtcg aaagcctaag aaaagaatta aacaaattaa ctggtaaaag aatccatatc
    50581 aatatcgtgg aaatcaaaaa accagatcta gatgcaaaat tagtaggtga aggaatcgca
    50641 cgtcaattag aaaaccgtgt tgctttccgt cgcgctcaaa aacaagccat ccaacgctca
    50701 atgcgtgctg gcgctcaagg gatcaaaact caagtatctg gtcgtctaaa cggagcagat
    50761 atcgctcgtt cagaaggata ctcagaagga actgttcctc ttcatacttt acgtgcggac
    50821 attgattacg catgggaaga agcagataca acatacggaa aactaggagt taaagtgtgg
    50881 atctatcgtg gagaaattct tccaactaaa aaaaacactg agaaaggagg gaaataatca
    50941 tgttagtacc taaacgtgta aaacaccgtc gtgaattccg cggaaaaatg cgcggggaag
    51001 ctaaaggcgg aaaagaagta gcattcggtg aatacggttt gcaagctgtt gattcacatt
    51061 ggatcacaaa ccgccaaatc gaagctgctc gtatcgcaat gactcgttac atgaaacgtg
    51121 gtgggaaagt atggattaaa attttccctc acaaatctta tactgccaaa gcaattgggg
    51181 tacgtatggg ttctggtaaa ggggcacctg aaggatgggt tgcaccagta aaacgtggta
    51241 aaatcatgtt tgaaatcgca ggcgttcctg aagaagtagc tcgtgaagcg ttacgtctag
    51301 cttctcacaa attaccaatg aaaactaaga tcgtaaaacg tgaggaaatg ggtggtgaat
    51361 cgaatgaagg ttaaagaaat cagagaatta accactgccg aaatgcttga tcaagaaaaa
    51421 caattaaaag aagaattgtt taatcttaga ttccaattag caacaggtca attagaaaac
    51481 actgcacgta ttaaagaagt acgtaaatcg attgcacgca tcaaaactgt gttgcgtgaa
    51541 caagctaagt aattatggaa ggaggccatt aagcgtatga ctgaaggaag aaatcaacgc
    51601 aaagtttatc aaggtcgcgt ggtttcagac aaaatggata aaacaattac cgttgctgtc
    51661 gaaacaaaga aaaaccaccc tatctatggc aaacgcatga actattctaa gaaatacaaa
    51721 gtgcatgatg aaaacaacac agcaaaagtt ggcgacatcg tgagaattat ggaaactcgt
    51781 ccattatcag ctacaaaacg tttccgtttg ttggaagtag tcgaagaagc agttattatc
    51841 taataacacg agattttcct atatagattg aatgcaaaat ctgaaaggag gatacacaac
    51901 gtgatccaag cagaaagtcg tttaaaagtc gctgataact caggcgcacg tgaaattttg
    51961 acgatcaaag tccttggtgg atctggtcgt aaaactgcta acatcggtga tgtgatcgtt
    52021 gctacggtta aacaagcaac gccaggtggg gttgtcaaaa aaggtgacgt cgttaaagcc
    52081 gttatcgttc gaacaaaatc aggagctcgt cgtacagacg gttcatatat taaatttgat
    52141 gaaaatgctg cagtgattat tcgtgatgat aaaagccctc gtggaacacg tatctttggg
    52201 ccagttgcac gtgaactacg tgaaaacaac ttcatgaaga tcgtttcact agcaccagaa
    52261 gttttataat cttgagacac ttatcaaagg aggtgcgaaa cagttatgtt tgttaaaaaa
    52321 ggcgataaag ttaaagttat cactggaaaa gacaaaaaca aagaaggcgt tgtactagca
    52381 gcgttcccga aaaaagataa agttattgtc gaaggtgtaa atgtcgttaa aaaacaccaa
    52441 aaaccttctc aagctgctcc tcaaggtgga attgttgaga tggaagcgcc aattcatgtt
    52501 tctaacgtga tggtggttga ctctactggt gtagctggcc gagttggcta caaagaagta
    52561 gacggcaaaa aagtccgtgt ttctaaaaaa accggtgaag ttttagataa ataaaagttt
    52621 aaggaaggag ggtcttactg aatgaaccgc ctaaaagaaa aatatcttaa agaagtaact
    52681 ccatcattga tggaaaaatt taactatagc tctgttatgc aaacacctaa agttgaaaaa
    52741 atcgtcatca acatgggtgt tggtgatgcg gtatcaaacg ctaaaaactt agataaagca
    52801 gttgaagaat taactttgat cactggtcaa aaaccaatga ttacaaaagc taaaaaatca
    52861 atcgctggat tccgtttacg tgaaggaatg ccaattggtg caaaagttac attgcgcgga
    52921 gaaagaatgt acgaattctt agacaaattg gtttctgttt cactaccacg tgtacgtgac
    52981 ttccatggtg taagtaaaaa agcctttgac ggtcgtggaa actatacttt aggtattaaa
    53041 gaacaattga tcttcccaga agtagattat gatttagtag ataaagtacg tggtatggac
    53101 atcgttattg taacaacagc aaactctgat gaagaatctc gtgagttgtt gacacaatta
    53161 ggcatgccat tccaaaaata attaaaggag gcgaactacg tggctaaaaa atcaatgatt
    53221 gctaaaaaca aacgtcctgc aaaattttca acacaagctt atactcgttg cgaacgttgc
    53281 ggacgtccac attcagttta tcgtaagttc catctttgcc gtatttgctt ccgcgaactt
    53341 gcctataaag gtcaaattcc cggcgtgaag aaagctagct ggtaaaaagt aaattcgcat
    53401 aagaaggagg taaaagatca atggtcatga cagatccaat tgcagatttt ctaactcgta
    53461 tccgtaacgc aaacatggtt aaacatgagt ctttagaagt acctgcatca aaaattaaac
    53521 gtgacatcgc tgaaatcttg aaacgtgaag gtttcgttcg tgatgttgaa tacatcgaag
    53581 atgacaaaca aggcgtgatc cgtgttttcc taaaatttgg taaaaacggc gaacgtgtta
    53641 tcacaaactt aaaacgtatc tctaaaccag gtttgcgtgc ttatgtcaaa gctgacgaag
    53701 taccaaaagt attgaacggt ttaggtatcg caatcatttc gacttctgaa ggtgttgtca
    53761 ctgataaaga agctcgtgaa aaaaatatcg gcggcgaagt tatcgcttac gtatggtaat
    53821 caagtagaat ctacaaggag gtgtctttaa gtgagccgta tcggaaataa agtcgttgtt
    53881 atccctgaag gagtaacagt tactcaagac ggaaacaacg ttacagttaa aggaccaaaa
    53941 ggtgaattga ctcgtacttt ttcagcagat atcaaaatga atatcgaagg aaacgaagta
    54001 actttcactc gtccaaacga cagtaaagaa atgaaaacaa ttcatggaac aactcgtgcg
    54061 aacttcaaca acatggttgt aggtgtcagc gaaggtttcc aaaaagcgtt agaactaatc
    54121 ggggttgggt accgtgcaca attacaagga tcaaaacttg tattgaacgt tggttactca
    54181 catccagtag aaatcacacc accagctgga gtaactgttg aagtaccagc taacacacaa
    54241 gtaattgtta aaggtgcgaa caaagaagaa gttggcgaat tagctgcaaa cattcgtgga
    54301 actcgtcctc cagaacctta taaaggtaaa ggtattcgtt atgttggcga atatgtacgc
    54361 cgtaaagaag gtaaaactgg taaataatcg tttagaaaaa ttgcatagaa gccagcagca
    54421 ggaaaaaggc atttggctga agtttacctt caaaaaaata catttttact tgtgccgcag
    54481 cttctatttt tcgaaacgta tttactgctt gaaatagtag tacaataaaa ataaagaggt
    54541 gacaattgtg attacaaaac cagataagaa caaaacacgt caaaagagac atcgtcgtgt
    54601 acgtaacaat atctctggta ctgctgagcg cccacgcttg aacgtttttc gttctaacaa
    54661 aaacatctac gctcaaatta ttgatgacgt agcgggtgta acgctagcaa gtgcctctac
    54721 cttggataaa gaaatttcag gtggaacaaa aacagaagca gcacaagctg tcggtaaact
    54781 agttgctgaa cgtgcagctg aaaaaggcat taaagtagta gtctttgacc gtggtggata
    54841 cctttaccat ggccgtgtgc aagctttagc tgaagctgct cgcgaaaatg gactagaatt
    54901 ttagaagaag gaggaatacc attcatggtt tatatcgatc caaaacattt ggaattagaa
    54961 gaccgcgttg ttgcaattaa ccgtgtaaca aaagttgtta aaggtggacg tcgtctacgt
    55021 tttgctgctt tagttgttgt cggtgacaaa aacggacacg tagggtttgg tacaggtaaa
    55081 gctcaagaag ttcctgaagc aatccgtaaa gcaattgaag atgcgaagaa aaacttagtt
    55141 gaagtaccta tggttggttc aacaatccca cacgaagtaa tcggtgcttt tagtggtggt
    55201 agaatcctaa tgaaacctgc tgtagaaggt tctggggttg ctgctggtgg accagttcgt
    55261 gccgtattag aattagctgg ggtagcagat atcacttcta aatctttagg ctcaaataca
    55321 ccaatcaacg ttgttcgcgc aacagttgaa ggtttgaaac aattgaaacg tgcagaagaa
    55381 gttgcagaac ttcgcggcaa atcagttgaa gaattaatcg gataaggagg acaacaataa
    55441 tggctgaatt aaaagttact ttaaaacgca gtattatcgg acgtcctcaa aaccaacgcg
    55501 atacagttaa agcgttaggt cttacaaaga ttaacagttc agtggttaag ccttctaatg
    55561 aagcaattaa aggcatgatc aatactgttt ctcacctagt ggacgttgaa gaaatttaat
    55621 ttagaaaaat cataactaga acattaagga ggtgccaaac ctatgaaact tcatgaatta
    55681 aaacctgctg aaggttcacg ccaagtacgt aaccgtgttg gtcgtggtac ttcatctggt
    55741 aacggaaaaa ctgccggacg cggacaaaaa ggacaaaaag ctcgttcagg cggcggtgtg
    55801 cgtttaggat ttgaaggggg acaaacacca ttgttccgtc gtttaccaaa acgaggattc
    55861 acaaacgtga accgtaaaga ctatgcagtc attaatcttg atgtattgaa ccgctttgaa
    55921 gacggagctg aagtaactcc tgttgcttta gttgaagctg gaatcgtgaa aaacgaaaaa
    55981 gctggaatca aagtattagc taatggggaa ctaaacaaga aattaactgt gaaagcagca
    56041 aaattctcta aagcagctca agaagcaatt gaagcggctg gtggatcaat cgaggtgatc
    56101 taatgtttag actattaaaa gatgctttta aagtaaaaga cattagatcg aaaatcctat
    56161 ttactgtatt tgtgttgttt gtatttcgcc taggtgcaca tattactgta ccaggcgtaa
    56221 atgctgcttc attgcaaaac ctttcttctt tgccattttt caacatgttg aacttggtaa
    56281 gtggtagtgc gatgcaaaac ttttccattt tctcaatggg ggtttcacca tacattactg
    56341 cttctatcgt cattcagctt cttcaaatgg acatcgtgcc tcgatttgtt gaatggtcga
    56401 aacaagggga agttggtcgt aaaaaactga atcaagcgac tcgatatctg acattagtat
    56461 tggcatttat ccaatctgtc ggtatcactg ctggattcaa tcaatacgct caattaggtt
    56521 tcgtgaataa tcctaacgta gcaacttacg taacgatcgg tttgattcta acagccggta
    56581 cgatgtttgt tacttggcta ggagaacaga tcacagaaaa aggtatcgga aatggcgtat
    56641 caatgatcat ttttgcaggt atcatttcta gattgcctga aagtatcaga gaaatttatg
    56701 aagattactt tataaatatt gatccttcag acatatggaa atctgctatt tttgtggcca
    56761 ttttactagt agcggtcttg ttgatcgtga cattcgtaac atttttccaa caagctgaac
    56821 gcaagatccc gatccaatat acgaaacgcg tagctggcgc gcctacaagc agctatctgc
    56881 cgttgaaagt aaatgcagct ggagttattc cagttatctt tgctagttcg tttattgcta
    56941 cgccaaatgc tgttttacaa gcattgagcg gtagattcgg ttctgaaaac tggtacaaag
    57001 tgatgatgga gatctttaac tataatacag cacctggtgc tacgatttat acgattctga
    57061 tcgttgcctt cactttcttc tacgcctttg ttcaagtaaa ccctgagaaa ttagcggaaa
    57121 acttgcaaaa gcaaggaagt tatataccaa gcgtacgccc tggtaagggg actgaagagt
    57181 atgtctcaag attactgatg cgtttaagta cagttggtgc agtcttcctt ggtttagtgg
    57241 cattgcttcc aatcattgct caaatggttt gggatcttcc acaatcaatc ggattaggcg
    57301 gtacaagctt actgatcgtt atcggtgtag ctttagaaac tgcgaaacag ttagaaggct
    57361 taatgctgaa acgtaaatat gttggattca ttgagtaaga aagcgtgttg aggtttcccc
    57421 tcaacacacg ttctcacaca tttattagga gggaaaacaa tgaacctcat tttaatgggg
    57481 ctgccaggcg caggtaaagg aacacaagct gaaaaaatca ttgatgctta tggtattccg
    57541 cacatctcaa caggagatat gttccgcgca gcgatgcaaa acgaaacagc tcttggcctg
    57601 gaagcaaagt cttatatgga taaaggtgca ttagttcctg atgaagtaac aaatggaatc
    57661 gtgaaagagc gactagctga accagataca gagaaaggct tcttattaga tggctttcca
    57721 cgtacgctag atcaagcaaa agctctggac gcaatgctaa aagatttgaa taaaaaaatt
    57781 gatgctgtca tcgatatcca tgttggtgaa gaaatcttgg tcgaacgtct agccggccga
    57841 tttatctgca gcaattgtgg agcaacttac cataaaattt tcaaccctac aaaagttgaa
    57901 gacacatgtg atcgttgcgg tgggcatgaa ttctatcaaa gagaagatga taaacctgag
    57961 acggttaaaa atcgtctggc tatcaacatc aaaaatagtg aaccaatctt ggcttattat
    58021 aaagaacaag gtttgctaaa cactattgat ggtgctcgtg aaatcgatgc tgtatttgca
    58081 gatgtacaaa aaatcattga aaaatagcac gattgcccgt agccgacttg cattatgcag
    58141 ttactcttgt caagttcaat aaattatgat agaatatgtc agtccgactt ctagagaatc
    58201 ctctagatga tccattttga gaattttgag gtgggaactg cagtttccgc cattttatcg
    58261 tgtgaaaatg cgaaacaagt acaaggaggt actgtgcgtg gcaaaagaag atatgattga
    58321 agtcgaaggt acagtcgtcg aaactttgcc gaatgcaatg tttaaagttg aactagaaaa
    58381 cggacaccaa gttcttgcta ctgtttcagg taaaattcgt atgcattaca tccgtatctt
    58441 acctggtgac aaagtaacgg ttgaattgtc tccatacgat cttaaccgtg gccgtattac
    58501 ttatcgcttt aaataattgt actccgtaaa actacaggag gtattatcat gaaagtaaga
    58561 ccatcagtaa aaccaatgtg cgaacattgt aaagtaattc gtcgtaaagg acgcgttatg
    58621 gtgatttgcc cagcaaatcc aaaacataaa caacgtcaag gataattgga ggtgctataa
    58681 atatggctcg tattgcagga gtagatattc ctcgtgataa acgtgtagta gtttcactta
    58741 cttatatcta tggtattggt aacactactg ctaaaaagat cttagctgat gctggtgtat
    58801 ctgaagatgt tcgcgttcgt gaattaacga atgaacaaac agatgctatc cgtgcagaag
    58861 tagataaatt aaaagttgaa ggggatcttc gtcgtgaagt gaacttgaac atcaaacgtt
    58921 tgatggaaat cggttcttac cgtggaatcc gtcatcgccg tggattgcct gttcgtggac
    58981 aaaacacgaa aaacaatgca cgtactcgta aaggcccagc tcgcgctatc gctggcaaga
    59041 aaaaataatt cttaagtgaa ggaggttaaa acttcatggc agcaaaaaaa gtgaatcgta
    59101 aacgccgtgt gaagaagaat atagaagcag gtattgcaca tatccattct acattcaata
    59161 acactatcat catgatcact gatactcacg gaaatgcatt agcgtggtca tcagctggtt
    59221 cattaggttt caaaggaagc aaaaaatcaa ctccttttgc cgctcaaatg gcagcagaaa
    59281 ctgctacaaa agcagcaatg gaacacggat taaagactgt tgaagtaaca gttaaaggac
    59341 ctggttctgg acgtgaagca gcaattcgtt cattacaagc tacaggttta gaagtgactg
    59401 caattcgtga cgtgactcca gttcctcata atggtgcccg ccctccaaaa cgccgtcgtg
    59461 tttaatgagt gccgctcatt ttgagtttta tcagtaacgt cattgaacaa gacacttttc
    59521 gttttgaaag gggtaaagat aagaatgatt gagttcgaaa aaccaagaat cgcaaaaatt
    59581 gatgaagaaa aagattatgg caagttcatc gttgaacctc ttgaaagagg gtatgggact
    59641 actttaggga attccctacg tcgtatttta ttatcttctt tgccaggtgc tgccatcact
    59701 aatattcaaa tcgatggtgt actgcatgaa ttctctacca tcaaaggtgt tagagaagac
    59761 gtcactcaaa tcatcttgaa cattaaaggc ttagcgctga aaatgtatgg ccaagaagaa
    59821 aaaacccttg aaatcgatat taccggacct gctacagtaa ctgctggcga tattatcgtt
    59881 gatagtgatg tagaaattct taacaaagat atgtacatct gtagtgtctc tgaaggagct
    59941 acgttccatg ctcgcttaac agtgaaacct ggacgtggtt atgttcaagc agatgaaaat
    60001 aaaaaagaag atatgccaat tggcgttctt ccagtcgatt caatctacac acctgttcgt
    60061 cgtgtgaact atcaagttga gaacacacgt gttggacacc gtgaagattt tgataaattg
    60121 acgatggaga tttggacaga tggttcaatt gaaccgttgg aagcaatgag tttgtctgcg
    60181 aaaatcatga ctgaacattt ggatattttt gtgaacttaa ctgatgaagc aaaaaatgct
    60241 gaaatcatgg tcgaaaaaga agaaacacaa aaagaaaaaa tgttggaaat gacgatcgaa
    60301 gagttagact tgtctgttcg ctcttacaat tgtttgaaac gtgcaggaat caatactgta
    60361 caagaactta caaataaatc tgagcctgaa atgatcaaag tccgtaactt aggacgtaaa
    60421 tcattagaag aagttaaagc aaaattgcac gacttaggtt taggtttacg taaagaagat
    60481 taaaaccttt tacgaaggag ggaaaccaac gtgagttatc gtaaactagg acgcacatct
    60541 agccaacgta aagcgatgtt gcgtgattta acaactgatt tattaatcaa cgaacgtatt
    60601 gtgactactg aagctcgtgc gaaagaagtt cgctcaactg cagaaaaaat gatcacttta
    60661 ggtaaacgcg gagatttgca tgcacgtcgt caagctgcgg ctttcgtacg taatgaagtt
    60721 gccagcgtgc gtgaagaaaa tgaggacatc gtcattgaat cagctttaca aaaactgttc
    60781 aacgatattg cacctcgtta cgcagaacgt caaggcggat acacacgcat tttgaagaca
    60841 gaaccaagac gcggtgatgg tgcaccaatg gttgtcttag aacttgtcta aaatcacact
    60901 aataacatca ctttatagat gattctttta gagtgttatg atgttggaag atatttttcc
    60961 gagtctagct cagcgctgct cctcaagcga atatcgcttg gggagtaagc actcatcata
    61021 aagtgttttt ttataccttc aattacctgt catgacagat atgtttgaag gcataaaaaa
    61081 acattttaag cgagaaataa ttgaaaattt tgtctttttt tgatagtgtt agtaggaact
    61141 ttaggatgaa gaaggagtaa tcatggagcc aattattgaa ttagaaaaga taaattataa
    61201 ataccagcca gatgatcttc gccccgcatt gaaagatgtc tcctttacaa ttgataaagg
    61261 tgagtggatc gctattattg gacacaatgg ttcaggaaaa tcgacacttg ccaaaacgat
    61321 caatggattg cttctgccag aatcagggat cgtgaaagtg ggaaatcaaa tattggatga
    61381 agaaaatatt tggacgatcc gacagatggt tggaatgatt tttcaaaatc cagacaatca
    61441 gtttgttggt tcgacagtag aagatgacgt tgcttttggt cttgaaaatc aagggattcc
    61501 cagagaagaa atgctagtgc gtgtgaaaga tgcacttgag aaagttagaa tggctgagtt
    61561 tgcttcacgc gagcctgctc gtttatcagg agggcaaaaa caacgtgttg ccattgccgg
    61621 cgtggttgcc ttacgacctg atatcattat tttagatgaa gcaaccagta tgctagatcc
    61681 agaaggtcgt gaagaagtga tctctacgat caagaagatc aaagaagaaa gtcaattgac
    61741 cgttatatct atcactcatg atattgatga agcagctaat gccaatcgga tactagtgat
    61801 gagacaaggc gaacttgtcc gtgaaggtac accaaaagaa attttttctg ctggtcctga
    61861 actgatcgac ttaggtctag atctaccatt tcctgaaaaa ctgaagagcg cactgaaaga
    61921 acgtggggtt gatgtgccca gtgaatatat gacagaagaa aggatggtgg attggttatg
    61981 gacatccgtt ttgaacaagt agacttcact tatcagccga atacaccatt tgaacaaaga
    62041 gccttatttg acatcaatat gacgatcaaa gaaaacagtt atactgcatt agtagggcat
    62101 accggaagcg ggaaatcaac cttacttcag catttgaatg cgcttgttaa gccaacaagc
    62161 ggtacagtcc atattggaga acgagatatt cagccggata cggataataa gaatttaaag
    62221 cccatccgaa aaaaagttgg catcgtcttt cagtttccag aagcacagct attcgaagaa
    62281 acggtagcaa aagacattgc tttcggtcct aaaaactttg gtgtcagcga agaagaagca
    62341 ctagtcctag caaaagaaac attagaacaa gttgggctgg atgaaagcta tttggaacgt
    62401 tcgccatttg aactttcagg agggcaaatg cgtagagtag caatcgctgg tgtgcttgcc
    62461 atgaggccgg aagtacttgt attggatgaa ccaacggcag gacttgatcc ccagggcaga
    62521 aaagaaatga tggagatgtt ttggcgtctt cataaggaac agcagatcac tattgtatta
    62581 gttacgcatt taatggatga tgtagccaat tttgcagatt atgtctatgt gttggaaaag
    62641 ggacgaatcg ttaatagcgg ggagccgcaa gaggtctttc aaaacattga atggctaaaa
    62701 gaaaaacaac taggcgtacc tactgccacc gagtttgcag aagaattaat ggctaaaggg
    62761 atgaactttg ctaccttgcc tttgacagct gaagaattag cagacgctat cgtccattat
    62821 gctggaggaa atgcccatga tgaataaatt gatatttggt cgttatatgc ctggagattc
    62881 cttgatccat cgattggatc cccgagctaa attattagcc agtttttatt ttatcggaat
    62941 cattttttta gcaaataatt gggaaacgta ccttttgttg gcatttttca cattactttc
    63001 tgtcttcttg tcaaaagtag atttgaaatt ttttatccga ggcattcgcc cattgatctg
    63061 gctaatcctc ttcactgtag ctttgcaggt cttgtttaca agtggcggag aaacttattg
    63121 gagttggggt gttttccata tcactgaatt tggtgtgatg aacggcctct ttattttctg
    63181 tcgattcgtg ttgatcattt ttatgtcgac tctactcacg cttactacac cgcctttgga
    63241 attatcggat gcgattgagt acttgcttcg tccattgaaa gccgtacggt tcccagtcca
    63301 cgaaatttca ttgatgctgt cgattgctct tcgttttgtg cctacattga tggacgaaac
    63361 agaaaagatc atgaacgctc agcgcgctcg cggtgttgat tttggtgaag gaaacctagt
    63421 tcagaaaatg aaagcagtca ttcctttgct gattccttta tttgtcagca gcttcaaccg
    63481 tgcggaagat cttgcgactg ctatggaagc aagaggctac aaaggtgggg aaggaagaac
    63541 gaaatatcgt gtattgcatt ggcataatag agacacgatg gttatcattg cttttgtatt
    63601 attaactgtg ctactgatct ttttaagagg ataaacgttc agtgggccgc tatctattct
    63661 tttcttgctg atctgtttgc aagaaaggat gcaagcagtg tatgacaaga aatattaggg
    63721 tctgtggcag actaaggtca caggcctctt tcttttatct gaaaagaaag aacgaaaaaa
    63781 ttttatagaa aaatcattat tccagataac cttttaggaa caaaggagag aaaaacatgg
    63841 tacgttacaa agcaatcatt gcgtacgacg gaacaaattt taatggattc caaaaacagc
    63901 caaatgggcg tactgttcaa gaagaagtag aaaaaacatt acaaaaaatg gcaaatggaa
    63961 aagaaatcac ggtctttggt tcgggaagga cagatgccgg agtacatgcg atcgggcaag
    64021 taatccattt tgattatcca gaggagcgtc cgttagaacg aatgcgtttc gcgctagata
    64081 cccagtcacc agaggatatt gctgtaagac aagtagaaat tgtttcagaa gacttccacg
    64141 caagatattt ggtcaaagaa aagacgtatc aatttcgagt ggatataggg aaaccacgca
    64201 gtccttttcg acgccattat gcaagttatt ttccttaccc acttgatttg gaaaaaattc
    64261 agcgggcgct tcctgattta ttagggactc acgatttcac ctctttttgt gcatcaggaa
    64321 gctcgataga ggataaaata cgtacgatct acgaggctaa gatggaggta aatgaaacaa
    64381 aagacgaatt gttgtttaca tttaggggaa atggcttctt gtataagatg atacggatct
    64441 tagtaggaac gcttttgaaa attggcaatg gccgattgcc tgaagatagt atcccagata
    64501 ttattgcgaa aaaagatcgt aatgcagcag gacctacagc acaccctgaa ggactttatt
    64561 tgtatgaagt gaaatatgaa taagaggtta tgatagaagt ggtcagcttc aagaaataag
    64621 aaggtattta cgaaaattac ttctcaaaat tttgcaaaat ttcggcttat tttcgaagaa
    64681 gctacttctg gaacaccgtt taagaaagag gtcgtgagcc tgtcatttaa ctctgagtca
    64741 caaagagcaa tttcaaaaaa cagcttctca tctttgatga atatcgtgac ttgtggacga
    64801 ggcgttgata agtgaatcat ctttttgtta cctatttttt ctgtaaccaa aaaacgatgg
    64861 aacgttgttt tgattgccct tggtgcggac agtctgaaca ggttccatcg tttctttatt
    64921 ttctacgtct tcttctgtgt gtgtttcgtg gttgttcttc tattgctgga tcaatcgtgc
    64981 cataaaaggg gcgattgcgg tcaaggtacc agacataaag aataaacaat gcaatacata
    65041 ggacaaaaag gattgcacct atcgtaaatc cttcaggcaa gtaactgaaa gtgacagtat
    65101 gtttacctgc tggaactttt atcatcaaga atgcgtcttt gaaattgctg accttgactg
    65161 gtttcccatc aattttagct ttccatcctt tgtcataagg aatagttgtc accaacatgg
    65221 aatcttcagc ggtatttaca gtcccagaag cttttctgcc agtggcttcc atttcgacac
    65281 ctttttcttt gatctgattc attgcggctt gataggctac aacatctaga ccaacgactt
    65341 taggctccat gaaacttatt tctttcgtcc cataaaaact tgcagtaaat gtcactgttg
    65401 tctcttgagg ataatagcca agatcatagt attgaccaga aatgttgatt tgcgtttttc
    65461 gcgatgtacc attgacagtg atcgtcgcac tagaactttc taattgcgca aaattggttg
    65521 ggaacaaact taagtaagct tgtgtatttg caggcacatg gacttcccaa gtgagctctt
    65581 ttggctggtt atctgctgtt tctgagtaag tgacgccagt cgttgtcttt gtgatcgtcg
    65641 tattcaactg attcttcaaa gtaggtgtat agaatgtaaa atactgttca tttagaccag
    65701 acaatgtatt gatcaagttt gtctgactgg tcaaattatc tgtcactggc tgctcaacat
    65761 cattaacgga caacggtgca gtaaatgcta gtggcaatgc attgacattc tgatacagtg
    65821 tatagtcgcc gctttgacca gcttggcgga agccatattt actgaacgtg ctttcgtttt
    65881 tagaaatgtt atatttgatt cctgtaaacc catccatcag caaagtatta ttgttataac
    65941 ggatattcaa atttgtccct cttgaacgga aacctaattt atccaggtaa gaggaagaat
    66001 tacgatttct tatagaagaa aacaaactga taccactgta accatagttg atcgaatcgt
    66061 ttgcagatac tggatccaga ttttccaagc ggtaaaacga gtcggaatct ttttttgttt
    66121 catttacaag agctttcaag tcaggataag gatcagtata taaactgcgg gaagcataat
    66181 tccaatcatc aagaatgcca tggatcatac tgttcgtatt gaccagtgct tcagcagaca
    66241 tgatcaataa taacaatata ctcagatgat tgaatgaaag ttttttatgc tgataaaatc
    66301 ccacagcaaa agcataaatc cctaagaaaa ccactgtcaa tacaaaggaa gtcatcgtca
    66361 cataggtgta gcttccttca ggtttgatgc cccatgccac cgcaaagaga gcagctacga
    66421 ccaaaatgat tcctaacaac agcccaccat cgtcttgttc tatcttttcc catccttttc
    66481 ctgcaagcag gagcactaag aaagagaaca gataggcata acggaataaa aacatattcg
    66541 gtgcatgcat accatgccag aacaaattca atggaacaag ataaaaactt gcgataagta
    66601 tggcgaaaag actgccgtac aaaaatttat ttttcaacgg tactttccga ctggcaaaat
    66661 aaaacagaca gaggactaat ggtagcagac ctgcgtaaac gaacggaatc gatccgtatt
    66721 ttgtcgtgtc ataaacacca atcatatttt tcatgattag atccagataa gaagtcgctt
    66781 ctgttttcaa cgtagtgatc tgactcagtg cctcgccatt tgaccgaaga tccagcactg
    66841 ctggcaatac aatgatcatt gaagcgccgc ctgccagtaa agaagtgata ccataaggaa
    66901 caatcgtttt tttatattct gaccagtttg tcaatagacg ggcgataaaa tataagaaag
    66961 aaaatacgcc aatcataaaa cccatataaa aactggataa aaacaagagt aaataactga
    67021 taaataaaag tttcggccgt ttaagatcca taacacgatg aatccccaaa atcactaatg
    67081 gaagataaac aaatgcatcc agccacatga tgatctccga atgtgcagtg ataaatgaga
    67141 tcaatgcgta actgacgcta agtgcaacat gcccccagcg aggaatcttg aacgtacgtg
    67201 caagaaacca aaaagccaat ccggcacagc cgaccttaag caaagtcaga acatacagtg
    67261 catctggcat catctggttt ggaaaaaaga acaccagtgg cgtgaagatc ccgcctagat
    67321 agtaagaaat taaagataaa taattcaatc ctagagaagc attccatgta taaaaaatac
    67381 tttgctttcc aagaagaaca tttcggaagc tggcatgaaa attagaaaac tgtgaaaagg
    67441 catcacttgc caaaatactt ctgctgcttc caggatagat tccgatactt agataaacaa
    67501 gtgctaaaat caaaaacgga atcaggaaac tagctgctgc gtagcgtccg ttttctctaa
    67561 agaatgactt taaatttttt ttcatattta ttttccacca aatttctatg aagttgtatt
    67621 cagtttatca tatccttgtt tttctctgct taaaaagagt ctagttttca caaaaaaata
    67681 aaatttagaa taaataactt cataatttgt tcgtataaca aaaataaacg caaaaaaagg
    67741 gtaggaatca aaagtcccac ccttaaaaat ttttattaaa taaaaaaccg ttcactatct
    67801 gaacggtcca agtatcattc aattaaacgc gttcaacttt tcctgatttc aaagcacgag
    67861 ttgacaccca aactttttta ggttttccgt cgaccataac gcgaactttt tgtaagttag
    67921 gtttaacagt acgttttgtt gagttcatag cgtgtgaacg gttgtttcca ctttttgtct
    67981 tgcgacctgt aaagtaacaa acttttgcca tggtaatttc ctcctttgcc ttgatttgga
    68041 gcaatagaat aattcagctc ataccagact aacatatcat atagaatggg aatttgcaag
    68101 tacattttca tagatacaat tgacaattga gaagaataat tgtaaattaa acaaggttat
    68161 acctgaaatt ttgcaaggtt tttgagtact ttgggtaact gccttttatt tcaagttgcg
    68221 ctatgataaa atatgataga agaaaaatgg gagtttttta cccgttaagg aggctcattc
    68281 atggctgtaa aaattcaaac gtcagctgga accattgaaa ttaccaatga tgtaattgca
    68341 acagttgttg gtggcgccgc gacagatgtg ttcggtgttg taggaatggc cagcaaaaat
    68401 caaattaaag ataatattac tgagattttg cgtaaagaaa attactcaag aggagtagtt
    68461 gtccgccaag aagataatgg tattgctgta gatgtttata cgattatcag ctatggtacg
    68521 aaaatctctg aagtttcccg caacgtccaa gaaaaagtga aatacaatct agaggcatta
    68581 ttaggcgtaa ctgccaattc agttaatgtc tttgtacaag gtgttcgtgt actgccagac
    68641 taggcaggag actggctggt aactcagcag tcgatctgaa ggaggattat ctaggtgagt
    68701 gtaacagaaa taagtgcaag ccagttccag gaaatggtcc aggcaggtgc gaatcgtctg
    68761 caagtaaatg cagaatacgt caattcatta aatgtattcc ctgtgccaga tggcgatacg
    68821 ggaacaaata tgaatctatc tatgactagt ggagctaagg cagtagtaga ttcaacctca
    68881 gaaaaagtag gagaattagc agcaatgctt tcaaaaggat tgctgatggg tgcgcgcgga
    68941 aattccggcg ttattttgtc tcaattgttt cgtggatttt ctaagcaaat tccagatgtt
    69001 gtctcattaa atgcttctga tcttgctgca gccttcactc atggagttga aactgcgtat
    69061 aaagcagtaa tgaaaccagt agaaggaacg attttgacag tagctagaga agcagcgaaa
    69121 gctggagaaa agaaagcaaa aagtactgat gatgtcgttg aagtaatgac agctgttgta
    69181 aaaggagcaa agcgtgcttt agctaaaact ccagacttgc ttccagtcct aaaagaagtc
    69241 ggtgtcgtag acagtggagg gcaaggactg ctgtttgttt atgagggctt tttaagtgca
    69301 ttgaatggag aattccaagc ggatgaaaca tatgaacctt ctccagcaga aatggatgat
    69361 atggtcaatg cagaacatca tcgcagtgtc caaggtcaaa tggcgacaga agatatccat
    69421 tttggttact gtacagaaat catggtaaaa atcggagaag gacctacagt cgatagtaca
    69481 ttcgattacg aagaattccg taactattta gatggtatag gagattcttt acttgtggtc
    69541 aatgatgacg agatcatcaa agtccacgtg catacagaaa acccaggaga agtcttgaat
    69601 tatggacaaa aattcggttc attagtcaaa atcaaagtcg acaacatgcg cttgcagcat
    69661 gagacgattt tggaacacga tgaagaagtg aacgagtttg cgaaaaaaga aataccacgt
    69721 atcccgtatg gtatcgtagc gatcgctgct ggtaaaggcg tccaagagct gtttgaaagt
    69781 ttaggcgcta attatgttat cagtggtgga caaacaatga atccaagtac ggaagacatt
    69841 gttaaagcga ttcaagaagt aaacgcagat aaagtgattg tcttgccaaa caataagaac
    69901 atcttcatgg cagctgatca agcagcagaa gtagcagata tcccagtagc agttgttcct
    69961 tcaagaacga tttcccaagg attgacagct atgctttcat tcaatgatca agcttcttta
    70021 gaagaaaaca aagaaacgat gacagaaatg ttgtctagcg ttgtgagcgg tcaagtcact
    70081 cacgcgatca gagatacctc aattgacggt gtagagatca aagaaggaga ctttttgggc
    70141 atgatcgatg gaaaaatcct gatctctaac ccagatatca cagcaacagc gttaagtaca
    70201 ctagaacaaa tgatcaatga ggacacagag atcgtaacga tcttggcagg tgatgaagga
    70261 acagttgaac aagcaaatga atttgctgag aaactaacag aaaaacatcc tgatttggaa
    70321 atcgagatcc accaaggaga tcagcctgtc tatccttatc tattttctgc tgaataattt
    70381 ctgtgtcaga atatctttct aacacagtat tcattcataa aaggccttcg gttagtgatc
    70441 aggtatgatc gctgaccaag tccttttttt gttaaaggag ggaggaaaaa tttatgcgtt
    70501 ctttagatga tccaatcact atgctggcag gagtcggaga aaaaagagca gctagtcttg
    70561 ccagcttggg catccaaacg attgaagact tactgactta ttatcctttt cgctacgaag
    70621 atattcagga aagaaatcta aacgagatcc aggatcaaga aaaggttact ttgaaaggaa
    70681 tcgtagtctc gcctcctgtg atgaatcgat ttggttataa aaaaagccga ttgcaatttc
    70741 gtatgatgca agaacatgat gtgttcaacg tttctttttt taatcaacct tatctaaaag
    70801 aaaaagtcat tttatcggag gaaatcgccg tatacggtaa atgggatgca aagcgtaaag
    70861 ccttgaacgg gatgaagatt ttaggttctc aaacaatgga tgacttttcg ccgatatatc
    70921 acgtcaacaa atcaattcgt caaacgacat tagttgatct aatcaaaaaa gggtttcaag
    70981 aatacggcac attgattgaa gaaaatctgc caaacaacct tgtggagaaa tatcgactgc
    71041 ttgaccgagc ttctgctgta agaagtatgc attttccaaa agaccacgaa gaaaaccatc
    71101 aagccaaacg acgtgtcgtt tttgaagagt tctttttatt tcaaatgcgt cttcaaggat
    71161 tgaaaaaagc agaaaaagca gaaacgaatg gtttggagat cctttatgat gtccaaaaat
    71221 tgaaacaatt tactcaaaag ctaccttttg aactgacaaa tgcacaaaaa cgtgtaacga
    71281 atgaaatctg tcgggatctt cgcagtccgc agcatatgca gcgacttttg cagggagatg
    71341 taggtagcgg aaaaacagtg gttgccgcga ttgcgttata cgctaccgtt acagcaggtt
    71401 tccaaggtgc gttgatggtg cctacagaaa tcttggcaca acaacatatg gaaagcttgc
    71461 aacagctgtt tgatcccaat gaagtaacca tcgcattgat tacggggtca acgaaagcaa
    71521 aagaacgacg tgagctcctt gaaaaactag agcaagggga aattaacgtc gtgatcggca
    71581 cacatgcatt gatccaagat ggagtcgaat ttcagaattt aggtctagtt attacggatg
    71641 agcagcaccg ttttggcgtg aaccagcgga aagtacttcg tgaaaaaggc tggcgaccag
    71701 atgtcttatt tatgacagcg actccgattc ctagaacatt agctattaca gcatatggtg
    71761 agatggatgt atctatcatt gatgaacttc cagctggacg tatcccgatc gaaacacgct
    71821 gggtaagaac acctcaattg gacagtgtac tggattggac gaaaaaagaa ctggcaagag
    71881 gacatcaaat gtatgtcatc tgtccgctga ttgaagaatc agaagcatta gatgtaaaaa
    71941 atgcagtgga aatctatgaa aaacttcgtg aactatttgc accaaaatat gaagttggct
    72001 tgttacatgg taaaatgaag aatcaggaaa aagaagtaat catggaagcc ttcaaagaca
    72061 accagatgca gatattagtt tcgactactg taattgaagt aggggtaaac gtgccgaacg
    72121 cgaccgtcat gctgatcatg gatgcggatc gatttggatt ggcacagctg caccaacttc
    72181 gtggacgtgt tggacgcgga agtgatgctt cctactgtat cttagttgct aatcctaaaa
    72241 atgaactagg tgtggaacgg atgaaaatca tgacagagac caccaatggt tttgtactaa
    72301 gcgaaaaaga tctggaatta cgtggtcctg gtgaagtatt tggcttccgt caatctggtc
    72361 tgcctcaatt tgcgattgct gacttggtga cggatggaaa tgttttggag gtagccagag
    72421 aagaggctgc agccctttgg caaataaagg attggcagat gcttcctgag tatcagcctt
    72481 tagcgcaaag cctccaaata gaaaatcagg ataatcgtta tttcgattag cagactgtgc
    72541 tatactttat actgatgacg gaaaaaggag tggaaacaat gaaaattgcc gtagatgcaa
    72601 tgggcggaga tcacgcacct caagcaattg tagaaggcgt ggctttagcg cagcaagatt
    72661 ttccagaagt agaattctta ctttacggaa aagaagcaga aatcaagaaa tacttaacaa
    72721 atgaaaaaaa catcacgatt atccatacag acgaaaaaat caatagtgat gatgagccag
    72781 taaaagcaat tcgacgaaaa aagactgcat caatggtcct tgctgcacaa gcagtgaaaa
    72841 acggtgaagc agatgctgta ttttcagcag ggaatacagg cgcgctacta gcagcagggt
    72901 tgttcatcgt aggacgtatc aaaaatatcg aacgccctgg cttgatgtct accttgccag
    72961 tagtagggaa agaaggtgcc ggtttcgata tgctggatct tggcgctaac gcagaaaaca
    73021 aaccagaaca tttgttgcaa tacggtattt taggttcttt ttatgcacgt aaagtccgag
    73081 gtatcggacg tcctcgtgtc gcactcttaa acaacggaac agaagcaaca aaaggtagtg
    73141 aagtgacgaa aaaagcctat gaactccttc agaatgaaac aagcttgaat tttattggaa
    73201 acgtagaagc tcgtgagcta ctcaatggtg tggctgatgt agtggtcaca gatggattta
    73261 caggcaacgc tgttttgaaa tctattgaag gaacagcaat gaatatgatg aatctattaa
    73321 aatctgctat tctaaatgaa gggatcaaag gaaaaatggg cgctatgctt ttaaaagacg
    73381 gcttacgttc tttgaaagca gaaatggatt attccaaaca tggcggtgcc gttttgtttg
    73441 gcttgaaagc accagtcatt aaaactcatg gagcaacagg ccccgatgct gttcgctata
    73501 cgatccgcca aatccacaca atgcttgaga cagatgtagt tggacaatta gtcgaacaat
    73561 ttgaaaaaag cgaagaatag tatttggata tctgaagcga tccgttccat tgaaaaaaag
    73621 gtggacattc ctgaaaaatg ccagtaaaat tagccatggt gtaggtaatt gacaagtgta
    73681 tgattcttgg aggtgaaaaa gttgactcgc gaagaagtat ttaacaaagt agcgaaaatt
    73741 atttcaaatc attttgagat agataccgat aaagtgacgg atgaattgaa catcaaagat
    73801 gatttaaaag ctgattcaat tagtattatg gaattcgttt tagagcttga agatgaattc
    73861 ggtacggaaa tttcagatga agacgctgaa caaattgaaa cagtcggtgg cgcagtagat
    73921 tatatcagca gccatcttaa ataatttcaa ataaaagcaa agaaggataa aaagctgcat
    73981 gcagcttttt atccttcttt ttttaatctt tttgacacgt aaaagtcatt tttctgataa
    74041 ttctggcgat aaacagaaat tatgttgcaa agtaaagcgg ttttctatat aattattaat
    74101 aattcattac acaaagataa gaataacctt tgttataaaa cgatttattc tgtgtaatgt
    74161 ccttttttat taagaaaaac ttccatttag gaagcagaga ggggtattcg attgtccgat
    74221 aaccaattat tagaagttca gaacctacat acaggattcc gactcaaaga tgactattac
    74281 gatgcagtag atgacgtttc atttacttta gacaaaaacg agattttagc aatcgttggg
    74341 gaatctgggt gcgggaaaag taccttggct actacgatta tgggattact tgatcctaat
    74401 aacacaaaaa ttacaggtga gattttatat aacgatctga atttaatcga cctgaacgaa
    74461 acgctctata ataaaatccg cggaaatgat atcggaatga ttttccaaga tccgttgtct
    74521 gcattaaatc ctctcatgag aatcgaagac cagatcaaag aaggactttc ctatcacaca
    74581 aagatgaatg cagaacagcg tcaagctcgt gcactagaat tgctagaaca agtagggatt
    74641 cctaatcctg cgagagttgg acgccaatat ccccatgaac tatcaggcgg tatgagacaa
    74701 cgtgtcatca tcgcaatcgc aatcgcctgc aaacctccaa tcgtcattgc agatgaaccg
    74761 acgacagccc tagatgtaac catccaagca cagattcttg atttactgaa agaccttcag
    74821 gaagaaacaa aaacagggat catcttgatc actcatgact taggagtcgt agcagaaatg
    74881 gctgatcgag tggcagtgat gtatggcgga cagttcgttg aagtagcagg tgtaaaagaa
    74941 ctgtttgatc atcctaagca tccttataca cgctctttac tgaactctat accacaagaa
    75001 ggaaatcatg atgcagaact ccatgtgatc gaaggtgtcg ttccttctct gaaaaacatg
    75061 cctcgtaaag gttgtcggtt tgcaccacgt attccatgga taccagcaag cgatcatgaa
    75121 gaagagccta tccttcatga agtcgcaccg aaccacttgg tacgttgctc ctgctataag
    75181 catttccact ttagagacga aaaaggagag gtgtagatga cagaattaat cacaatcaaa
    75241 gacctgaaag ttcattaccc tattcgcagt ggattcttca atcgagtaac ggatcatgta
    75301 tatgctgtag atggtgtgga ttttattatc gaaaaaggaa agacatatgg tttagtggga
    75361 gagtctggct ctggaaaatc tactacggga aaagccgttg tgggattaga aaaggtaaca
    75421 gccggacaaa tcatgtatga aggaaaagat gtaacgaagc gaagcaaccg caaaaaaatg
    75481 ggttataaca aggatgtgca gatgatcttc caagattcaa tgtccagttt gaatcctaaa
    75541 aagcgagtgt tggatatcat tgctgaaccc atccgaaatt ttgaacggtt aagcgatcaa
    75601 gaagaaaaga aaaaggtaaa aggactgcta gatatcgttg ggatgccgga agatgcgcta
    75661 tataaatatc ctcatgaatt ttcaggcgga caacgtcaac gtctaggagt agcccgtgct
    75721 gttgctacca atccaaaact gatcgtagcc gatgaacctg tatctgctct ggatctatct
    75781 gttcaagcgc aagtattgaa tttcatgaaa cgaatccagc aagaatacgg cctcagctat
    75841 ttattcattt cacatgattt aggtgtagta aaacacatgt gcgacaatat cgcaattatg
    75901 tacaaaggtc gatttgtaga aatcggtaca agagaagaca tttataatga cccgcgacat
    75961 atctatacga aacgtctgct ttcagctatt ccgcaaatcg atgtagaaaa tagggaaagc
    76021 cacaaagaaa atcgacgaag agtagaacaa gagtatatcc aaaaccaaaa agaatactat
    76081 gatgcgactg gtcgagtcta cgatttgcgt acgatcacaa ctacacacaa agtggcgttg
    76141 aaagatggag gtgcaagcta atgtggaaaa cgattctgcg acgtgtttta ttgatgatcc
    76201 cgcaagttat tattttaagt gttctgatct tcttattagc ccaagcgatg ccgggggatc
    76261 catttaccgg tttgatcaat ccaaatcagg atccggcagt gatcgaacag atgcgacaag
    76321 cagctggctt gaatgaccca tggtatgtcc agtacttccg ttggatcgga aatgctttgc
    76381 aaggcgattt tggtcaaagt ttcttataca aacgctctgt tgctgacttg atcggcgaac
    76441 ggatcatcaa cactttatat ctatcgatct tgacagttgt ccttacttat ttgattgctg
    76501 tgcctctggg gatgcttgct ggccggtatc aaaattcaat cttggataag attgtcgtaa
    76561 tctacaactt ctttagtttt gctgttcctt tatttatctt cggcttgatc atgctatttg
    76621 tttttggtta tcgtttaggc tggttcccaa caagtggatc acaaacacta ggtttgcaag
    76681 gtggatttat cactcaatgg atagaccgtt tgaaatatat tctgttacca tcaattaccc
    76741 aagcattttt ggcgactgcc gtcacaatcc aatatctgcg aagtgaagta atcgattcga
    76801 aatcgctcga ttttgtcaga acagcccgtt ccaaaggggt accgacgaat aaagtattca
    76861 gtcgacatat tttccgaaat gcagcgttgc cgatggcttc tcaaatgggg tatgaaatca
    76921 cttcgttgat tgctggttct gtagttatcg aaaagatttt tggttatccg ggagtcggaa
    76981 aactatttat tgattccatc ggccaacggg actataccgt gatcacatcc ttagtattga
    77041 ttttaggaat cgcgacgcta gtggggacat tactttcaga tatcatcatg agtatcgttg
    77101 acccgcgtat tcggattcaa taaaaccaat cagaaaggag aatggatcga tgagtgaaaa
    77161 aaacaataca gcagttcaag aaagtattcc tcctatgggg atacgaatga ttgctcgaga
    77221 atttaaaaaa gataaaattg ctattttttc attaggtttg ctagtggttt tattattagt
    77281 gatctttatc ggtgcgatgc tgaccgatca agacaaagtg atgtatgtta gtatcttcga
    77341 caaatacgct gcaccaggaa cagtttcgac acaaggacaa aagttcattc tgggagcaga
    77401 tgaaggcgga cgtgatgtat taggacaatt gatcataggt gctagaaact ctgttacgat
    77461 cggatttgcg atcacgatcc ttacttcgat catcggggtt ggattaggga tcatctctgg
    77521 ctactacgga gggatcattg acaacatctt gatgcggatc gttgatttta tcatgattct
    77581 accgatcatg ctgatcatta tcgtcttcgt atcgattatt tccagataca atgtctggtc
    77641 ctttatattc atcatgagtg cattttattg ggtagctaaa gcccgattat tccgaagcaa
    77701 gacattatct gaagcaagaa gagattatgt cagtgcctca aaaacaatgg gaaccaatga
    77761 ttttaaaatc atgttccgcg aaatcatgcc gaatctaagt tcattaatca ttactaattt
    77821 gacgatgaac tttgcggcaa acatcggtat cgagacaact ttgactttct taggtttcgg
    77881 cttgccggca aatgtaccta gtttaggtac attgatcggt tatgcaagta acggagaagt
    77941 cttagtgaat cggcaatgga tctggttacc cgcatcaatc cttattttag ttttgatgtt
    78001 gagtatcaat tatgttggac aagcattcaa gcgttctgca gatgcgcgcc aacggttagg
    78061 ctagtataga agcgaagggg gaaataggaa tgaagaaaac gatttttgga tttgcagcgc
    78121 tgatgtctgc tgtcgttctt gcagcatgcg ggggcggagg tacagatacc tctggaaaca
    78181 actctggagg caacggcaat aacaaagagg aattaacttt tccaattgca acaaaaaata
    78241 atgatgatgc aatcgaagac ggcgaattag aagctgcggt cgcaacggac agtcagttta
    78301 aaggattgtt ccagtgggag ttttaccaag attcatatga tgcagctttt atggctcctt
    78361 ctcatgaacc gctatttgca aacgatgacg atttcagaat cacagacgac ggagctgcaa
    78421 cgcttgatct agatgaagat acgaaaaaag cgacaatcaa agtaaaagac aacgtcaaat
    78481 ggtcagatgg tgaagatgta acggcggacg atgtgatttt cccttacgaa atcattggga
    78541 ataaagatta cactggtatc cgttatgacg acactttccg taacatcgta ggtatggaag
    78601 aatatcatga tggaagtgcc gacacaatct ccggaatcaa aaaaatagac gacaaaacag
    78661 ttgaaatcga atataaagaa gtaaacccaa gcatgcttca atcgggtggt ggtatctggt
    78721 catatgcagc accaaaacat acgttagaag gtgtagcaat caaagatatg gaatcaagcg
    78781 atcaagtacg taaaaatcca gtgacttttg gcccttatta catgagtaat atcgttgcag
    78841 gagaatcagt agaatacttg ccaaacgagc actactggaa tggtacgcct aaattgaaaa
    78901 agatcacgat gaaatctgta ccgatggcaa gtgcaactga agcattgaac tctaaattat
    78961 atgatatgat tttccaaatg ccaacagata cttacgatac ctataaagaa attgctggct
    79021 atacaaactt aggccgtgaa caaacttctt atacttatct aggattcaag ttaggtaaat
    79081 ggaatgcaga tacaaagagt gtggaataca atccagattc aaaaatggct gataaatcat
    79141 tacgtcaagc aatgggctat gcattagata ataatgcagt aggtgaacgt ttctatgcag
    79201 gtttgagaag caatgcgact tcattgattc ctccagtatt ccagtcatac catgatgatg
    79261 agatgaaagg attcacacaa gatctagaca aagcgaaaaa actattagat gatgctggct
    79321 acaaagatgt ggatgacgat ggtttaagag aagacaaaga tggaaataaa ctaacaatca
    79381 actttgcttc gatgtccggt ggggaaacag cgcaaccatt ggcagattac tatatccaac
    79441 aatggaaaga aattggtttg gatgtccaat acacaacagg tcgtctgatc gaattcaatt
    79501 ctttctatga taaattagaa aacgatgatc ctgaaattga tgtttaccaa gctgcttgga
    79561 atacaggaac tgatccaaat ccaagtggac tatggggacc aaatgctgcg ttcaactaca
    79621 ctcgttatga atcagaagaa aatacaaaat tgatcaacga tatcagttca agcaaagcat
    79681 ttgatgaaga gtaccaaaaa gaagcatatc aaaaatggca acaatatgca tttgaagaag
    79741 catttgcgat tccaacgttg ttccgtaatg aagtattgcc agtcaacgac cgtgtcaaag
    79801 actgggattg gtcttatgat gtaccaaacc catgggcaaa tgtttctgtt acagcagatt
    79861 cacgttcata atcactaaaa atgaccgaaa aagggcgatg tcctttttcg gttttttgat
    79921 atttttctgt ttatttctct aatattcagg tcaaggcgct gatttcatga cttctccaat
    79981 aaacggtgtt caaagtccag tttctcggta ttaagtcaaa tttatgcaaa aatatggaaa
    80041 gccattttca caaaattttt tcttcatact cgaaactaaa cgaatttttc acaacttctc
    80101 gtcaatcact aggattatta aagctttact taccttttga ccgaaccatt tcaaatttga
    80161 caaaaaacca gtataataag gaagtatcga aaaaatatcc ataaaaggaa tgtggaaaat
    80221 ggacaaccag ctgacaaaag aactaaaaga aaactataac atcgtttttc acgatctaaa
    80281 tttgcttgaa caagctttta cccattcatc ctatgtgaat gagcatcgca atctgcaatt
    80341 atcggataat gagcgacttg aatttttagg agatgccgtt ttagaactga tggtttctca
    80401 gtatttattc cgtttatatc ctcatttgcc agaaggaaaa ttgacaaaaa cacgagctgc
    80461 gatcgttcgc gaagacagct tgtcgaaatt tgccaaagaa tgtcactttg atcaatatgt
    80521 tttgttgggc aagggagaag agaattcagg aggacgtacg cgaccagcat tgctttgcga
    80581 cctattcgaa gcttttttag gcgcgttata tcttgaccag ggattcgaca cgacccatgc
    80641 attcatcgaa aaagtgattt ttcctaaagt caaagcaggt gctttttcac atgagatgga
    80701 tcataaaaca aaactacaag aagtcttgca aaaatcaggt gatgtatcaa tcgaataccg
    80761 attgatcaat gaagaaggtc cagctcatga acgagtattt tggatcgaag tttatgtaga
    80821 tgatcaattg attggcactg gacaagggaa atcgaaaaaa ttagcagaac aagctgcggc
    80881 ggaaaatgca ttggcagcac tgtaaaagta agtgagggaa agctttgtat ttgaaacgaa
    80941 ttgaaatagc cggttttaaa tcatttgcag acaagacagt cattgatttt gaaaatagcg
    81001 tcacagcagt ggttggacca aatggcagcg gaaaaagcaa tattacagag gctatccgct
    81061 gggtattagg agaacaatct gctaaaagtc tgcgaggcgg aaaaatgccg gatatcatct
    81121 ttgccggttc cgatacccgt aagcagctga atattgcaga agtcacagtg attttagaca
    81181 atagtgatca ttatctgcca ttggagtaca atgagatcag tgtaacccgc cgttatcgac
    81241 ggactgggga aagcgagttt ttcatcaata aacaaagctg cagattaaaa gatatccaag
    81301 aattgttctt agattctgga ttaggaaaag aatcgttctc aatcatttct caaggaaaag
    81361 tagaagcgat tttcagtagt aaaccggaag accgtcgtgg gatctttgaa gaagcagctg
    81421 gtgtcttgaa atacaagcag cggaaaaaga aagcagaaca gaagcttttt gaaacagaag
    81481 acaacctcag ccgcgtccaa gacatcatcc acgaattgga agaacagtta actcctttgg
    81541 ccgcccagag tgaggcagca aaggagtttt tacggctaaa agaaacactg actcaaaccg
    81601 atgtctcttt gatggttgct gaaatcaaga cagcaaaaaa agattgggac aacaaacaag
    81661 cacagcttgc gaaattcaat ctagaattag gcaaactatc tgagtcgatc caagaacaag
    81721 aatccatttt ggcgaagcag cgtaaagaaa atgcgcaagc cgatcgtctg atcgaaaaaa
    81781 atcagcaagt attattagat ctttcggaaa aactgaagca gacagaagga caaaaagatg
    81841 ttttgcagga gcggacaaag catacacaaa aaagctcgca agaatatcaa acttcattag
    81901 cagaagcaca aaaaaaggtt aaacattttg aaaagcttca agaaagcttg atgaaagcag
    81961 cagcagaaaa agaaacagag atccaaaaag ctgaagcaaa tctcataaaa acacagcaag
    82021 aattagaaaa ataccaaaaa tcaacgaaag aattattggc agaattaaga gatcaatatg
    82081 ttgatttgat gcaagaacaa gcagctgtag gaaacgaact gaagtatcta gaacgtcaat
    82141 atatacaaga aacagcaaaa agcaagcaga cgttagccaa gcaatcggaa gtagaagcat
    82201 cagtagaccg attgatctta caaaaagaag aattgacaca aaagcaggcg cagctaaaat
    82261 catctttaac tgaaacaaaa gagaagttag aaatgatcca acaaaacggg aaaaagttcc
    82321 aagaagcatt agcaaaagaa cagcctaaaa tgtatcaatt aatgaatcaa gtccagcagc
    82381 tacgtgctcg taagaaaagc cttcaagaaa tccaagaaaa ctattttggt ttttaccaag
    82441 gggttcgatt ggtcttgcag cataaacagc agctttcggg tattgtcgga gcagtggctg
    82501 aactgatcga tgttcctgca gatttcacgt tagctatcga aacagcttta ggtggggcag
    82561 cccagcatgt catcgttgaa aatgaaaaag atgctcggca agccatcacg tatttgaaac
    82621 agcaaagagg aggaagagca acattccttc cactgacgac aatcaaacca agacaattac
    82681 cggctcatat attgacacaa gcagcagctg tagaagggtt tatagggatt gccagtgaac
    82741 aagtcagtta tcccgatcaa atccaaactg tggttcaaaa cctgctagga acgatccttt
    82801 tagccaaaga cttaactagt gccaatgcaa tcgcgcaaac gatccgctat caatatcgag
    82861 tggtttcctt agaaggtgat gtgatgaatg ccggaggatc catgacaggt ggagcgaata
    82921 aacgaggaaa ccaaggcagt ttgtttgtac aaaatcaaga attgaaacag ttgactagtg
    82981 aatttgaaga agcagataaa caactccaag cacaagaaaa aaaagttcag gagctgcaac
    83041 aagaaacagc tcgtttagcc gaagaacaag aagttttgcg tacacgaggc gaacaattac
    83101 gttttgaaga acaagaagcg acaaatcagc tacaaaacat cataaatgaa cttgaacgtt
    83161 ttgaaaaaga aaagcaaatc tcaacttttg agacacgtga actgcagcag tttatcgaag
    83221 attacgaaaa gcaaacgaac gaattgaaag acaaacaaac agatcttgaa tcgcaacgac
    83281 aaaaaatcga cgaagaaatc aaatcgttaa gtcaagaaag cgaccagatg gaagccagaa
    83341 gagcacaagt acaaagtcaa aaagcacaag aacaagcaga tcttgctgtc ttgaaagagc
    83401 agtttaatca tctgcagatc cagctccgcg gtgcccgagt ccaaaaagca gaggcaaccg
    83461 aacgtcaaga agcgatagaa aagcagttgg cgacattgac agcagacttt tctgatcatg
    83521 aagtcacaga agaaagtttg gaaaaacaaa ttaacgaatt atctgctcag cgagaaacat
    83581 taaaagccga gttggcaaaa gccaaagagc agcgagatag aaggcaaaag gagatcgata
    83641 agcttgaagc agtcttggca gagcgtaatc gtgagcaaaa agcacgactg tcggaacaat
    83701 ccaaattaga agtccaaaaa gaccgagctg aaatgatttt agataatcat ttgacctatc
    83761 tgcagtcaga atatcagctg acatttgaga aagcttccca agactatcaa gaaacaaccg
    83821 atatcgaaga cagtagaaca aaggtttcat ccttaaaaga acagattgaa aaactgggac
    83881 cagtaaactt aaattcaatc gaacaatacg aacaagtcag tgaaagacat acattcttag
    83941 caacacagcg agatgatctg ttagcagcga aaaaccaatt gtttgaaacg atggatgaga
    84001 tggatgatga agtgcggaca agattcaaag aagtatttga agctatccgt caagaattca
    84061 aaattgtctt tccaaatatg tttggcggcg gtaaagctga attagtactg acggaaccaa
    84121 ctgatttgct gaaaacaggt attgagattg aagtacaacc tcctggcaaa aaactgcaaa
    84181 gtctaagttt gctttctgga ggagaacgag cacttacagc catcgcgttg ctcttttcca
    84241 ttatccgtgt ctgtcctgtt ccgttttgta tcttagatga ggtagaagca gcgttagatg
    84301 aagccaacgt gaaacgtttt ggtcgttact tgagcgattt ccaagatgac acacaattta
    84361 tcgtagtcac acaccgcaaa ggaacgatgg tcgcagcaga tgtactgtac ggagtgacga
    84421 tgcaggaatc cggtgtatca aaaatcgttt ctgtacggat ggaagatatc aatgaagagg
    84481 cgaaaatcaa cgaaacgaaa gtgtaggaac gaaaatgatc aaattagtag caatcgattt
    84541 ggacggtaca ttattaaatg aacaaaagct gatttcagat gagaataaac aagcattagc
    84601 acaagcaaaa cagcaagggg tcaagatcgt tctatgtaca ggacgcccct tagctgcgat
    84661 ggcgcattat ctgcaagaat taggactggt agatgaaggt gactacagca tcactttcaa
    84721 cggcggtttg gtacaaaaaa atgatactgg tgaaatcatg gaaaagaaag tgatggaagt
    84781 atcagatatc caacgcttat acaaactggc tcagcaattg gatctgccac tagatgtttt
    84841 gtctgacaat gtggttttac agctgcctag tgccccaagg aagcaatcct tgtacaatgt
    84901 gttgaataag ctgctgcaat tccaaccagc ggatataagc gatattacag atgaatttgt
    84961 gcttaataag gcagtaatcg cttatgacca agaagaatta gatcctaaaa tcaaagaaat
    85021 accagcagaa ttccatgaaa tgtatgagat catcaaaaca agaagtatgc ttttggaatt
    85081 tatgccaaaa ggtgttacaa aagcttatgg tatttcttta ttggcaaaag atcttggttt
    85141 gaaacaagaa gaaatcatgg cgatcggtga tgaggaaaat gatttaccga tgatccaata
    85201 tgctggacta ggcgtagcga tggagaatgc tgtgcctttc gtcaaagaag cagcagattt
    85261 cgtgacagcc agcaatgaag aaaatggcgt agccaaagtg atccaaaaat ttgtattaga
    85321 gtagggggag tcaaatggga ttttttgata aaatcaagcg tgcttttact ggcgaagaga
    85381 aaacagaaga agttgaagta caggagaagt acgacaaggg tttagaaaag acgcgtaaaa
    85441 catttggtga acggatgaat gagttgtttg ccaattttcg aacagtcgat gaagactttt
    85501 ttgaagaatt agaagaaaca cttatcggtg cagatgtagg ttttgaaaca gcgatacgaa
    85561 ttaccgaagc attacgtcaa gaagtgaaac tcagaaatgc gaaaaaatcg gcagaagtcc
    85621 aaaatgcgat catcgagaaa cttgtggatc tctatgaagc ggaaggaatc aatgaagtaa
    85681 atgaactaaa tatccaagaa gacggactaa cagttatttt gtttgtcggt gttaatggtg
    85741 tagggaaaac aacaagtatt ggtaaacttg cccatcagtt caaaaacgaa ggtaaaaaag
    85801 tattgatggc agcagcagat accttccgcg ctggagcaat cgaccagtta gttgtctggg
    85861 gcgaacgcgc tggtgttgaa gttgttcgtg gcaatgcagg aggcgatcca gcagctgtcg
    85921 tattcgatgc tttggaaaga gcaaagacag agcaggcaga tgttttacta gttgatactg
    85981 caggccgact gcaaaataaa gtgaacttga tgaacgaatt agaaaaaata aaacgagtaa
    86041 tccagcggga attaccagaa gcaccccaag aaacacttct tgtattagat gcaaccactg
    86101 gtcaaaacgc gatggttcaa gcaaaacaat tcaaagaaac aacagatgtg accggtcttg
    86161 ttttgacaaa attagatggt acagcaaagg gcggtatcgt acttgctatc cgtaatgaat
    86221 tgcatttacc agtgaaattg gtcggtcttg gtgaaggaat cgatgacttg gagccgtttg
    86281 atccaaatga ttttgtcgtt ggattgttca aaggattact aaaagaagaa taacccatgt
    86341 ctaaaaagca ggagctgtga caaaagttgc agctccttgt ttgaatgatt gtttttaaca
    86401 tagctgtgtt tttgatgcct tcatttttat acttatttgt aagcggttct caaacaattt
    86461 cgttcttttt cttagacttt ttgattataa ttagattcat atgaattgga ggtcacttaa
    86521 tgatgaattt taagcaatta ttattgcatg tcaatgcgcg cccttttatc gaccaagctc
    86581 gatttggtat agaacgggaa ggacagcggg ttgatcttgc aggaaatcta gcaaaaaccg
    86641 atcatccagc aatctttggc gatcgatcct atcaccccta tatccaaaca gattttagcg
    86701 aaacacaaac agagatgatc acccctgtta ccgattctat tcccgaatta tttcagtatc
    86761 tcgctgctgt ttatgatgtg actgctcgtt ctataccgaa agaagagatg atctggccat
    86821 taagtatgcc acctgcctta ccggaaaaag acgaagagat cattattgca aaattaaaaa
    86881 atttcgaaga tgtcttgtat cgacgttatt tagcaaaaga atacgggaag cgaaaacaga
    86941 tggtaagcgg tattcatttc aattttgaat ttggcgatga gttgctaaga acattgttca
    87001 gccatcagga agaatttcaa gatttttccg aattcaaaac agaactttat ttgaaaacag
    87061 cgagaaactt tatgcgctat cgctggatga tcacttattt attcggtgct tcaccaatga
    87121 gtgagaagaa ctacttttta gatgaatcac atccgcaaga acctgttcgc agtattcgca
    87181 acagtgcgct gggctatacg aatcatccaa atgtgaaagt ttcctatgct tctatgaaac
    87241 agtatttagc agatatcgag cgaatgatcg aagaagggaa actttcggag gagaaagaat
    87301 tttatacacc gcttcgtttc cgaggcggaa agaaagtcgc agatttagca acaacaggtg
    87361 ttcgttatat tgaattgcgg aatatcgatt tgaatcctta tgcaagattg ggtatcaatc
    87421 cagagcaagt tcggttctta caattattcc tgatgtacat gttatggaca gaagaaaaag
    87481 aagactgtga ccaatgggta gcagaaggta cgactcgaaa taacaaagta gcactagaac
    87541 aaccatcaga tcaaacagaa tttcatcaag aaggtagaga aattcttgaa ggaatgaagc
    87601 aaatgctggt tgaattggat tggttggatt ctctttattt agtagaggaa gcattgactc
    87661 aaatggatca tcctgaacaa acgttagcag cgaaactcta tcaagaagca cagctatcga
    87721 gtcagcaaga agttgctgtg gcattgggac atcaatatta taaagaaagc catgaacgtc
    87781 cctatcagtt ggccggtttt cgcgaaatgg aactttctac tcagatattt atgttcgatg
    87841 ccatccaaaa aggtgtccaa gtcaaagtat tagatgagtc ggatcaattt ttgcgtctgc
    87901 aattccaaga ccatgtagaa tatgtgaaaa atgcaaacat gacaagtaag gacagctata
    87961 tcgtcccact tatcatggaa aacaaaacag taacgaaaaa agtcttaaaa gaagctgggt
    88021 tccgggtacc aggaggcgca gaattttcat ccatggaaga agcggtaaaa gcttatccga
    88081 gatttgccga gcaggcattt gtgatcaaac ctaaatcaac caattacggg ttaggtatca
    88141 cgattttcaa ggaaggagct agtctggaag attatcaagc aggtttagcc attgcttttc
    88201 gtgaagacag ttcggtttta gtagaagaat ttatgccggg aacggaatat cgtttctttg
    88261 tgatcgacgg agaagtccaa gccatcatgt tgcgagtccc tgctaatgtt attggtgaca
    88321 gtatccgaac agtgaaagaa cttgttgaag aaaaaaatag tgaccctttg cgtggaacga
    88381 atcatcgtgc acctttagaa ttgatccaat taggtgaatt agaacaattg atgttgaaag
    88441 aacaagggtt gacgatcgaa tcagttcccc aagccaatca aattgtttat ctaagggaga
    88501 actcaaatat cagtacaggt ggtgattcga tcgatatgac tgatgaattt tctgaagctt
    88561 acaaaaaaat cgccgtttct gcggtagaag cactaggagc taagattagt ggtatcgatt
    88621 tgattatacc agataaagaa atcgatccta caactgataa aaaagcatat gggatcatcg
    88681 aagcaaattt caatccagcc atgcatatgc atgtttatcc ttttgcagga aaaggcagaa
    88741 gattgacgat gaatgtattg aaattgttat atcctgaagt attttaaaag aaaaagcttt
    88801 tgacagattg tcctatttga tgtcaatctg atcaaaagct ttttttgcat gtaaaaattt
    88861 atgtgttttt tcgttttaaa ataaacgatc ccagaagctt tttttctttt ttggtttttc
    88921 tttttcagct ggcgaagagt tttcttctgg gtattttttt tcgatatcaa tcacaggttc
    88981 atttactgct tcttttgctg ttaagagcaa tccgaattcc tcaggatttg cagtgacgta
    89041 atcgttgact acagtgaaac ggctattgtt tttcgttgct agctggatat attggttttg
    89101 gacagaaagg ggtagagccc cattcaagag tatggaagca tctggatgtt ttttgagttc
    89161 ttttaaaaag ttttctttgt tttttggttg gatcatttca gcaacagtca tactaagata
    89221 gcagcgttcc ctgaatgtcc ctaaatattt atgctgttct tcagggttca ctaaaggtgt
    89281 accataaagt cccttatcca aatggctttt tacatcatct tgtgccataa aaaataccct
    89341 ccttcttctc tttgtctttc ttacgattat agcatattcc caataatacc taaaacatat
    89401 gaaaaagcgg ttgcttttgt tcaacgattc acttaaaata agaatgaaaa tcattctcaa
    89461 ttagaaaggt ggattggatg cgctacggac gactagtagc attattagtt attttaagta
    89521 gtatttcatt gttcatcgga gtatcgaatg tacaattgtc agaactgctc cagttagatg
    89581 ggcaaagctt acaaatcttg ctagtgactc gtttgccacg aacgatttgt ttgatccttg
    89641 tgggagcgac cagtagtatt tgtgggttga tcatgcaaca tttgacccaa aataaatttg
    89701 tttcaccaac gactgcgggc acgatggata gtgcgcgttt aggtatttta gtggctatga
    89761 ttttcctacc tggtgcatcc ttgattgtcc gatccttgac agcattttgc tttgcttttg
    89821 caggaacatt gcttttttta tcccttacgc gattgttcct ccagaaaaat caattgatgc
    89881 ttccgttgat tggagtcatg ttagggaata tcattggttc agttgctact ttttttgctt
    89941 atcaattcca gttggtacaa aatatgactt catggcttca agggaatttt gcgactgtga
    90001 tacgaggaaa ttatgagtta ttgtatgctg ttgttccatt gttgctcttg gtttggctat
    90061 ttgcttaccg atttacgatc attggtctgg gcgaatcgtt tgcagtaaat ctgggaatag
    90121 attaccagaa gatgcagttt ttaggcattg gcttagtatc attggctagt gcagtcatgt
    90181 tgatcatggt aggaagcatt ccttttatcg gagtgatcat tccgaatctt gtctctagaa
    90241 tatatggaga tcaagtgcac aaaacaattg gcgtaactgc tttagcaggt agtttgttct
    90301 tagtattttg cgatcttgtc gctcgcgtgt tgatttttcc ttatgaaata ccagtcagtg
    90361 tgatcgttgg aatcatcggt ggggctatct tcctttatct tctgataagg ggacgacgat
    90421 atgcttaaaa aaaagccatc tatttttatt ggtatgcttg ttcttgtttt atttgttaca
    90481 ggaatgtact tgacgatcca tacatatgga aactggcatt ttgcatgtgc attgaggagt
    90541 aagaaaattt ttgcatttat ccttgtctcg ctagctgtca gcagtgccac aatcagcttt
    90601 cagacaatta cgcataacca gtttttgact ccttcagtat tgggacttga gtcgttatat
    90661 gtccttgtcc aaacggtcct tttcttcttt atcggaggag tgacgatgct tcagcagaca
    90721 ggtacagttt ttttcttatt gaacgttggg ctgatggtcg ggctgagtct attgttattt
    90781 ttctttcttt tgaaaaaaat gagagcgaat ctttttttat tactgatgtc agggatgatt
    90841 ttaggtacgc tttttggtag tgtcagtacc tttttacaag tcatcatgga tccgaatgaa
    90901 tatgatttgc ttcaaggcag attatttgca agctttggca atatccagag tcagtatctt
    90961 ttgcctgctt ctttgatcat tatcggctgc tggtacctgt tatttcgata tcgacatgtg
    91021 ctagacgttt tccatctcgg aaatgaacaa gcagtaaacc tcgggataga cacagatcgt
    91081 tttgaatttt tgattttatg ttgtgtcagt cttttgacag ggacatcaac ggctcttgtg
    91141 ggtccagtta cttttttagg gtttattgtc gcaaatatca gttatcgtgt cttttctact
    91201 tatcgtcatg gtcagctatt tatcggaagc tttctggtag ctatgctgtt tctgacagga
    91261 ggacagctcg cagtagagca gattttcggc tggaatacaa cagtgagtgt cgtcgttgaa
    91321 tttgtcggag gaatttattt tgtcacaaaa ttgattcgcg aaaggaagag tatcctatga
    91381 ttgatttaca aaaggtcaat aaactgtacc atggaaaatc agtggttaaa gatgtacagt
    91441 taacgattcc tgaaaagaaa ttgactgctt ttatcggtcc aaatggtgct ggaaagtcaa
    91501 cggtgttgtc gatgatcagt cgtttgatac caaaagatac aggtgaaatc tatttagacc
    91561 ataacgaagt aaaggcttgg aaatccaatg aattagccaa aaaattatcg atcctacgac
    91621 aatcgaatga aataaatgtc caaatcaccg tgaaagaatt agtagaattt ggacgatttc
    91681 cttatacgaa aggaaaattg acgacaaaag acgaggaaat cgttcaggaa tcactggaac
    91741 accttgggtt agaagaaata gcggatcaat cgattgacac tctttcaggc ggtcaactcc
    91801 aacgtgcgta tattgcaatg gtgctagcgc aagacacgga ttatatttta ctggatgaac
    91861 ctttgaacaa tctagatatg aattttgcgg ttcaaatcat gcagatttta aaaaatttag
    91921 tacaagaaat cgggaaaaca attgttattg ttcttcatga tatcaacttt gctgcaagtt
    91981 atgcagacga aattgttgca atgaaagatg gacagttatt tacgcaagga acgacccaag
    92041 aaatgataaa aaaagatgta ttggatgaat tatacgaaat ggacatacgg atttgtgaga
    92101 ttgaaggccg cagattctgt ctttatttct aaaactaaca ttaggagaga agagatgaaa
    92161 aaattagtag taggtatctt gattctagca tcatttggtt tagcagcatg tggaaatagc
    92221 aacaacacca gtcaggcaga cacaaaaaaa agcagcacac aaactgaaac tacattgacg
    92281 ataacagata gtaatggaga ccaaatcgag gtgccaaata atccagaaaa agtcgtcgta
    92341 ttcgacaatg gttctttaga tacgatggat gctcttggtg ttggagataa ggtagttgga
    92401 gcagctacaa gcagccttcc tgagtatctt tcatcctata aaaaagtaga atcagcaggt
    92461 ggaataaaag aaccagactt agaaaaaatt aatcagcttc agccagatct aatcatcatt
    92521 tctggccgac aaagagattt tcaaaaagat ctaagtcaaa ttgctccgac cattttcctt
    92581 tctttagatg cgaaaaatcc atgggaatct ttccagcaaa atgtcactgc tttaggggag
    92641 atctttggta agcaagaaga agctaaaact caattagagg aattatctag tgcaatcgat
    92701 cagacgaaaa agaaagcaga agctactgac aaaaaagcac tagtcacact tgtgaatgaa
    92761 gggcaattat cagcctacgg atctggttct agattcggtt tcatccatga tttatttggc
    92821 tttgaacaag cagatgatca aatcgaagca tccactcacg gtcaaagtgt ttcttatgaa
    92881 tatgtgctgg aaaaaaatcc ggatatctta tttgtagtag acagaacaaa agctattggt
    92941 ggagacgaca gcaaagatga tatttctgcc aatgaactgg tagcacaaac gaatgctggt
    93001 aaaaatcagc agatcatctc ccttgaacca gatgtctggt atttaagcgg gggcggttta
    93061 gaatcaatga aactgatgat cgaagatgtg aatcaagcat ttaaatagca taaataacag
    93121 aggattaaac tctcatacta tgtaacaata atgtttctta cattcttaaa tagcaagagc
    93181 ctatcctcaa agaagttatc aaaaaccatc cgtaaaatcg tattgatgat tttacggatg
    93241 gtttttattt atttgagaaa tcttttttca acgtgaattc attatctaca tcatacgggt
    93301 tgattctaga atggggagtg gcaaaaaata gtgtgatcca ttttttcagc atcaagatcg
    93361 cctcctttga tttgaatcaa aggtacaaag cgaaacttag ataaaactta aatttagata
    93421 tttttatttt gtaccgatct cttctttaaa cgatgttcca tctgctgctt ctcggcaata
    93481 agtccactag actagaaaat atgagaagct attttctgtc cagcgttctt attactcaaa
    93541 gcaaatcgca gttgtcacaa tctcttctaa acgatgttcc atctgctgct tctcggcaat
    93601 aagcccacta gactagaaaa tatgagaagc tattttctgt ccagcgttct tattactcaa
    93661 agcaaatcgc agttgtcaca atctcttcta aacaatgttc aatcagctga ccttcggtat
    93721 tagctcaaag cactgatttc acaacctcta tttaggcatg tgtctcagca agcggttgat
    93781 agttgatgat ctgcattttt cgataaaaat cggcgggaag cttactccac cgttttaata
    93841 attgatagaa ataactctct tctgctttga ttttatactc gcttaatatc aatccaaaac
    93901 tattcgtttt ttttgaagct aattttttat aaatatccaa tgctttggtt ttatcttcat
    93961 tgacaaagag tgtttttact tcaatataag aaccctcgat attttgtgtt tcttcgataa
    94021 aatagatgtt ttttatatat tccttcatag tgattcctcc aaagaagtct tttatttgat
    94081 aagtttactc taccgaagag ttgttaataa tccgtgaaca aaaagtaatt ctttttccaa
    94141 tagttgttaa aggtttttta ttttttatag tattttttgt tatttaagaa aggaataagg
    94201 ttaaacaaat aacaggttgc tttttgggtc tttttccgtt caagaaactg aacgaagaaa
    94261 agggaaagtt gtctcttttg tgataagaga aatcataata aacgaatgac ttactttcca
    94321 ataaattgag aacagtcaga accagacaaa ttagttgcat ctgatgaata aagtgattat
    94381 tctatgacat gaggtgatac agatgaaatt agaagtgaca aaagaagcac aagaagtatt
    94441 gaagaataaa ttagaagcag acgatcaact tttattagat atcgaaaacg gtgacggtcc
    94501 atttgcagaa agccaagtca gttgccaatt ggatacggca tttcgattga tcattgtcaa
    94561 aaaagataca caaacagatc taagtcttta ttctgtagtg gctgatacac cagttggacc
    94621 aatcaaaatc aaagacagtg caatacttta catggatgat ccatccacac ttgctttaga
    94681 accaacttat aatagtttac aattaaaagg accaagcggc ttgagaaaag gcaacttgca
    94741 agttgttcga aaagactaga gggataaaat gggaaaattg gcgatcatca gcgacctaca
    94801 tgtggacatc aataaattcg gcgaatcaga gctgatgcag ctttggcaag ttttgcaaaa
    94861 gcacaagatc actcggcttc atctagccgg agatacggct aataaagtag accgttgcct
    94921 agctgttgtc gaatttttcg tcaataaagg attatctacg acatttcatt tcggcaatca
    94981 cgagttggca gatgtgccca atgaacagat gatggaccat tttccagacc cacatttttt
    95041 aaatgaacgg tatattgctt taaatgagca gaccgttctt ttagggatga atggctggta
    95101 cgactatcag ttttccgaat tgaaagatta cgaggcaatc gtacgaatga agcgtttgta
    95161 ttggtatgat cggttcatcc agcgtgggaa aacagatctc gaggtcaatg cagaaatgct
    95221 tgcagctgca aaaaatttgc tagaccagct ggaagcaaaa aaacttgagg tgattttatc
    95281 cactcatttc gttcctaaac gggcatttat catgtatcaa tctgctcctt atgagcgttg
    95341 gaacaaatta aatgcatttt taggatcaga atcattcgga gaattacttg accgttattc
    95401 aaatatcaaa caagtagttt ttggccatac gcatcgtcgc tttgaagata aatccatcgg
    95461 tcacacgatt tacagctgca gaccttttgg ttattattat gaatggcagc tgacccgaga
    95521 ttttgtcttg aaagaacagt tgctagacag ctatgatcct atgaaattac gtgtcctctt
    95581 gcgtgcccat cacccagctt ttcaggccta tcaaacacaa catttgcaag aggaatttga
    95641 acaagcgatg acaatcgttc cgtattgaga cagcattagt aatgtgtaaa agaaaatacc
    95701 ttgtaaaaca taaggataag taagagcagt agatccattt atcgtggata tgctgctttt
    95761 tttgcggaaa ataatcagcg aatgtttatt tgatcggatg atttgtaact cgcagagtac
    95821 tagatgcaag cgtgtattct ttttttgaac gataatcaca aaaaaaaata ta
//
LOCUS       DAFTHM010000002        91947 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFTHM010000002 DAFTHM010000000
VERSION     DAFTHM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 91947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.002"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            117..1043
                     /gene="cysK"
                     /locus_tag="L7C88_000108"
     CDS             117..1043
                     /gene="cysK"
                     /locus_tag="L7C88_000108"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBP9556976.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            1279..1725
                     /locus_tag="L7C88_000109"
     CDS             1279..1725
                     /locus_tag="L7C88_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBP9556977.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            1998..3350
                     /locus_tag="L7C88_000110"
     CDS             1998..3350
                     /locus_tag="L7C88_000110"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBP9556978.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            3521..3808
                     /locus_tag="L7C88_000111"
     CDS             3521..3808
                     /locus_tag="L7C88_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9556979.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            4034..4477
                     /locus_tag="L7C88_000112"
     CDS             4034..4477
                     /locus_tag="L7C88_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBP9556980.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(4483..5667)
                     /locus_tag="L7C88_000113"
     CDS             complement(4483..5667)
                     /locus_tag="L7C88_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBP9556981.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            5935..6633
                     /locus_tag="L7C88_000114"
     CDS             5935..6633
                     /locus_tag="L7C88_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBP9556982.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            6640..7317
                     /gene="nth"
                     /locus_tag="L7C88_000115"
     CDS             6640..7317
                     /gene="nth"
                     /locus_tag="L7C88_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBP9556983.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(7443..7976)
                     /locus_tag="L7C88_000116"
     CDS             complement(7443..7976)
                     /locus_tag="L7C88_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9556984.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(8273..10654)
                     /locus_tag="L7C88_000117"
     CDS             complement(8273..10654)
                     /locus_tag="L7C88_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBP9556985.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(10644..11291)
                     /gene="recU"
                     /locus_tag="L7C88_000118"
     CDS             complement(10644..11291)
                     /gene="recU"
                     /locus_tag="L7C88_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBP9556986.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            11355..11894
                     /locus_tag="L7C88_000119"
     CDS             11355..11894
                     /locus_tag="L7C88_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBP9556987.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            11984..12403
                     /gene="gpsB"
                     /locus_tag="L7C88_000120"
     CDS             11984..12403
                     /gene="gpsB"
                     /locus_tag="L7C88_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBP9556988.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYEAYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            12425..12792
                     /gene="rnpB"
                     /locus_tag="L7C88_000121"
     ncRNA           12425..12792
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="L7C88_000121"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13001..14167
                     /locus_tag="L7C88_000122"
     CDS             13001..14167
                     /locus_tag="L7C88_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBP9556989.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            14213..15709
                     /locus_tag="L7C88_000123"
     CDS             14213..15709
                     /locus_tag="L7C88_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBP9556990.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            15790..16473
                     /locus_tag="L7C88_000124"
     CDS             15790..16473
                     /locus_tag="L7C88_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBP9556991.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            17118..18308
                     /locus_tag="L7C88_000125"
     CDS             17118..18308
                     /locus_tag="L7C88_000125"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBP9556992.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            18410..19363
                     /locus_tag="L7C88_000126"
     CDS             18410..19363
                     /locus_tag="L7C88_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBP9556993.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            19432..20781
                     /locus_tag="L7C88_000127"
     CDS             19432..20781
                     /locus_tag="L7C88_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9556994.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(20964..21287)
                     /locus_tag="L7C88_000128"
     CDS             complement(20964..21287)
                     /locus_tag="L7C88_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9556995.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            21416..22579
                     /locus_tag="L7C88_000129"
     CDS             21416..22579
                     /locus_tag="L7C88_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBP9556996.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            22649..23998
                     /locus_tag="L7C88_000130"
     CDS             22649..23998
                     /locus_tag="L7C88_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBP9556997.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(24043..24474)
                     /locus_tag="L7C88_000131"
     CDS             complement(24043..24474)
                     /locus_tag="L7C88_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9556998.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            24862..27504
                     /gene="alaS"
                     /locus_tag="L7C88_000132"
     CDS             24862..27504
                     /gene="alaS"
                     /locus_tag="L7C88_000132"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBP9556999.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKEHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27704..28300
                     /locus_tag="L7C88_000133"
     CDS             27704..28300
                     /locus_tag="L7C88_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBP9557000.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            28422..29570
                     /locus_tag="L7C88_000134"
     CDS             28422..29570
                     /locus_tag="L7C88_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBP9557001.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(29608..30021)
                     /locus_tag="L7C88_000135"
     CDS             complement(29608..30021)
                     /locus_tag="L7C88_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBP9557002.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            30100..30531
                     /locus_tag="L7C88_000136"
     CDS             30100..30531
                     /locus_tag="L7C88_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBP9557003.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(30630..30863)
                     /locus_tag="L7C88_000137"
     CDS             complement(30630..30863)
                     /locus_tag="L7C88_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBP9557004.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            31046..32716
                     /locus_tag="L7C88_000138"
     CDS             31046..32716
                     /locus_tag="L7C88_000138"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBP9557005.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            32863..33249
                     /locus_tag="L7C88_000139"
     CDS             32863..33249
                     /locus_tag="L7C88_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557006.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            33236..33934
                     /locus_tag="L7C88_000140"
     CDS             33236..33934
                     /locus_tag="L7C88_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBP9557007.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            33939..34403
                     /locus_tag="L7C88_000141"
     CDS             33939..34403
                     /locus_tag="L7C88_000141"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBP9557008.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            34400..35311
                     /locus_tag="L7C88_000142"
     CDS             34400..35311
                     /locus_tag="L7C88_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBP9557009.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            35546..36085
                     /gene="pyrR"
                     /locus_tag="L7C88_000143"
     CDS             35546..36085
                     /gene="pyrR"
                     /locus_tag="L7C88_000143"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBP9557010.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            36099..37382
                     /locus_tag="L7C88_000144"
     CDS             36099..37382
                     /locus_tag="L7C88_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBP9557011.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            37395..38321
                     /locus_tag="L7C88_000145"
     CDS             37395..38321
                     /locus_tag="L7C88_000145"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBP9557012.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            38340..39620
                     /locus_tag="L7C88_000146"
     CDS             38340..39620
                     /locus_tag="L7C88_000146"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBP9557013.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            39625..40701
                     /gene="carA"
                     /locus_tag="L7C88_000147"
     CDS             39625..40701
                     /gene="carA"
                     /locus_tag="L7C88_000147"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBP9557014.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            40706..43891
                     /gene="carB"
                     /locus_tag="L7C88_000148"
     CDS             40706..43891
                     /gene="carB"
                     /locus_tag="L7C88_000148"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBP9557015.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            43945..44721
                     /locus_tag="L7C88_000149"
     CDS             43945..44721
                     /locus_tag="L7C88_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBP9557016.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            44718..45650
                     /locus_tag="L7C88_000150"
     CDS             44718..45650
                     /locus_tag="L7C88_000150"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBP9557017.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            45647..46363
                     /gene="pyrF"
                     /locus_tag="L7C88_000151"
     CDS             45647..46363
                     /gene="pyrF"
                     /locus_tag="L7C88_000151"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBP9557018.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            46370..46999
                     /locus_tag="L7C88_000152"
     CDS             46370..46999
                     /locus_tag="L7C88_000152"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBP9557019.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            46987..47301
                     /locus_tag="L7C88_000153"
     CDS             46987..47301
                     /locus_tag="L7C88_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557020.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            47339..47980
                     /locus_tag="L7C88_000154"
     CDS             47339..47980
                     /locus_tag="L7C88_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBP9557021.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            48023..48715
                     /locus_tag="L7C88_000155"
     CDS             48023..48715
                     /locus_tag="L7C88_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBP9557022.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            48712..49614
                     /locus_tag="L7C88_000156"
     CDS             48712..49614
                     /locus_tag="L7C88_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBP9557023.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(49772..51478)
                     /gene="efbA"
                     /locus_tag="L7C88_000157"
     CDS             complement(49772..51478)
                     /gene="efbA"
                     /locus_tag="L7C88_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBP9557024.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            51668..52291
                     /locus_tag="L7C88_000158"
     CDS             51668..52291
                     /locus_tag="L7C88_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557025.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            52741..53790
                     /locus_tag="L7C88_000159"
     CDS             52741..53790
                     /locus_tag="L7C88_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBP9557026.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            53787..54668
                     /locus_tag="L7C88_000160"
     CDS             53787..54668
                     /locus_tag="L7C88_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557027.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            54671..55441
                     /locus_tag="L7C88_000161"
     CDS             54671..55441
                     /locus_tag="L7C88_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9557028.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            55720..56574
                     /gene="aroE"
                     /locus_tag="L7C88_000162"
     CDS             55720..56574
                     /gene="aroE"
                     /locus_tag="L7C88_000162"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBP9557029.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            56752..57915
                     /locus_tag="L7C88_000163"
     CDS             56752..57915
                     /locus_tag="L7C88_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBP9557030.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            58032..58442
                     /locus_tag="L7C88_000164"
     CDS             58032..58442
                     /locus_tag="L7C88_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBP9557031.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            58616..60844
                     /gene="topB"
                     /locus_tag="L7C88_000165"
     CDS             58616..60844
                     /gene="topB"
                     /locus_tag="L7C88_000165"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBP9557032.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            61015..61299
                     /locus_tag="L7C88_000166"
     CDS             61015..61299
                     /locus_tag="L7C88_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557033.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            61459..61695
                     /locus_tag="L7C88_000167"
     CDS             61459..61695
                     /locus_tag="L7C88_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBP9557034.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            61692..62091
                     /locus_tag="L7C88_000168"
                     /pseudo
     CDS             61692..62091
                     /locus_tag="L7C88_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
     gene            complement(62758..63702)
                     /locus_tag="L7C88_000169"
     CDS             complement(62758..63702)
                     /locus_tag="L7C88_000169"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBP9557035.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(63998..64942)
                     /locus_tag="L7C88_000170"
     CDS             complement(63998..64942)
                     /locus_tag="L7C88_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557036.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            65163..66377
                     /locus_tag="L7C88_000171"
     CDS             65163..66377
                     /locus_tag="L7C88_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9557037.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            66399..68414
                     /locus_tag="L7C88_000172"
     CDS             66399..68414
                     /locus_tag="L7C88_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBP9557038.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(68497..69870)
                     /locus_tag="L7C88_000173"
     CDS             complement(68497..69870)
                     /locus_tag="L7C88_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBP9557039.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(69896..70180)
                     /locus_tag="L7C88_000174"
     CDS             complement(69896..70180)
                     /locus_tag="L7C88_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9557040.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(70182..72197)
                     /locus_tag="L7C88_000175"
     CDS             complement(70182..72197)
                     /locus_tag="L7C88_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBP9557041.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(72376..72681)
                     /locus_tag="L7C88_000176"
     CDS             complement(72376..72681)
                     /locus_tag="L7C88_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBP9557042.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(72770..73801)
                     /locus_tag="L7C88_000177"
     CDS             complement(72770..73801)
                     /locus_tag="L7C88_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBP9557043.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            74008..74883
                     /locus_tag="L7C88_000178"
     CDS             74008..74883
                     /locus_tag="L7C88_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBP9557044.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(75035..75877)
                     /locus_tag="L7C88_000179"
     CDS             complement(75035..75877)
                     /locus_tag="L7C88_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBP9557045.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(75969..77846)
                     /locus_tag="L7C88_000180"
     CDS             complement(75969..77846)
                     /locus_tag="L7C88_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBP9557046.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(77843..79264)
                     /locus_tag="L7C88_000181"
     CDS             complement(77843..79264)
                     /locus_tag="L7C88_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBP9557047.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(79267..82656)
                     /locus_tag="L7C88_000182"
     CDS             complement(79267..82656)
                     /locus_tag="L7C88_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBP9557048.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            82913..84304
                     /locus_tag="L7C88_000183"
     CDS             82913..84304
                     /locus_tag="L7C88_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557049.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(84377..85024)
                     /locus_tag="L7C88_000184"
     CDS             complement(84377..85024)
                     /locus_tag="L7C88_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBP9557050.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(85032..85718)
                     /locus_tag="L7C88_000185"
     CDS             complement(85032..85718)
                     /locus_tag="L7C88_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557051.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(85724..86797)
                     /locus_tag="L7C88_000186"
     CDS             complement(85724..86797)
                     /locus_tag="L7C88_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557052.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            87019..87693
                     /locus_tag="L7C88_000187"
     CDS             87019..87693
                     /locus_tag="L7C88_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9557053.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            87698..89038
                     /locus_tag="L7C88_000188"
     CDS             87698..89038
                     /locus_tag="L7C88_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBP9557054.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(89187..90173)
                     /locus_tag="L7C88_000189"
     CDS             complement(89187..90173)
                     /locus_tag="L7C88_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBP9557055.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            90897..91928
                     /locus_tag="L7C88_000190"
     CDS             90897..91928
                     /locus_tag="L7C88_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBP9557056.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT        29408 a        16306 c        18667 g        27566 t
ORIGIN      
        1 taccatatat ggtatatctt tgtctttttt ttgctagtca aagacgaatc actcgccata
       61 aatgaacaga ttgtattatg ataagtaaga agagcaaaga caaggaggaa ttgaagatga
      121 cagctatcta taactcagtc accgaattga ttggcaaaac gccaatcgtc aaattaaata
      181 aaatcgtacc agaagattca gcagatgttt ttgtaaagct tgagtttttt aatccaggag
      241 gaagtgtaaa agatcgtatt gctttaagta tgatagaaaa agcagaacac gatggtctac
      301 tgaaaccagg tgatactatc attgaaccta cttctggaaa tacaggaatc ggattgtcga
      361 tggtaggagt tgcaaaagga tataaagtaa tcatcgtgat gcctgagacg atgagtatcg
      421 aaagacgttt attgatgaaa gggtacggcg cagagttgat tttgactcct ggtgcggatg
      481 gtatttctgg atcaatcaga gaagcagaac gtttggcaaa agaaaacggc tactttttac
      541 cattacaatt tgaaaatgaa gcaaatcctc ttgtgcatga gaagacgact ggtcctgaga
      601 tacatcaagc atttggagta aatggcttgg acgcgtttgt tgcaggtatc ggtacaggag
      661 gaacgatcac tggcgctggc cgagaattaa aacgtgtgta tccgaaaatc gaattaatcg
      721 gggtagaacc agcagaatct gctattttag aagggaaaga agcgggacct cacaaaatcc
      781 aaggaatcgg tacaggtttt gttcctaaaa cactggatac ttctgtgtat gataaagtcc
      841 tttctattag tggagacgaa gcgatggaaa cagctagaga agttgggcga aaagaaggga
      901 ttttagtagg catctcatct ggcgctgcaa ttgctgccgc gctaaaagtc gcaaaagaat
      961 taggaaaagg caagaaggta ttagctgtgg ttcccgacaa tggtgaacgt tatttatcta
     1021 cagcccttta ccaagagata taaggcactt ggtttttctc cagataggtt tatgtaaaaa
     1081 acttttaaag atgaaaagaa cacacaaaaa tttatgatga gaaaaattat ttgaatagag
     1141 acgtagaata gtgaacgcga ctgttttacg tcttttttca ttaaaataca ataaaattga
     1201 attttctttt catgttaagt ggattttaaa atgtaaaaat agtatgataa gacgagaata
     1261 acaacgtggg gtgtttacat ggaaaataag ttagtcgaag aggttatcga aaagttaaaa
     1321 aaagagaaca ttcgaatcac acctcaacgg tacgcggttt tagaatattt gattgaacat
     1381 cattcccatc caacggctga tgagatttat aaagcacttg aacatcggtt tccaaatatg
     1441 agtgttgcga ctgtttacaa taaccttcgc ttatttactt cgattggatt tgttcaagaa
     1501 atgaagtacg gcgatgcttc tagccgattt gatttcagtt caaagcgtca ttatcatgta
     1561 atttgtgaaa actgcggtaa gattgttgat tttcattacc cagggcttga agatatagaa
     1621 atggctgcaa gcagactgac tgattttgag attaatgaac atcggttgga attgtatgga
     1681 ctctgtccgg attgtaaaga gtcagcaaaa aaggcgcaaa tgtaaaaaca gtttctacaa
     1741 gtgttatacc taaaaaaagc tagctgtgta aaaaaaacgc tagctttttt atttttttgt
     1801 cttttattca caatcttaga tataaaagtg aatattatta aaataagaat cttgtagata
     1861 ttgggttctt atgcttgaaa aggaatgaaa ctacaaacaa acctttgtga attcacaagc
     1921 attaaactgt tgtatccgtt ttatttctgt tatagtagtt ttgtcgaagg acaaaatgtt
     1981 aatcggaggg accataaatg aaagtagtag taattggctg tactcatgca ggtactgcag
     2041 ctgtaaaaag tattttaaaa aatcatccag aagcagaagt gacagtatat gaaagaaatg
     2101 acaatatttc tttcttatct tgcggtatcg cactttatgt cggcggagta gtaaaggacc
     2161 cagcaggctt gttctactca aatcctgaag aattatcttc attaggagca acagttaaaa
     2221 tggaacacga tgtaacagac gtcgatacag aaaataaaac agtaacggca aaagatctga
     2281 aaacaggaga aacagaaacg gtttcttatg ataaattagt gatgacaact ggttcatggc
     2341 ctattatccc accgattagt ggaatcgatg cgaaaaatgt actcctatgc aaaaactaca
     2401 atcaagcaaa tgaaattatt gcacaagcga aagaagcaaa acgtgtagta attgttggtg
     2461 gtggatatat cggtattgaa ttagtagaag cttttgtcga atctggaaaa caagtgacat
     2521 tgattgatgg attagatcgc atcttgaata aatatctaga taaaccattc acagatatct
     2581 tagaaaaaga attgacagac cgcggtgtta ctcttgcgct aggcgaaaat gttactgaat
     2641 ttatcacaga tgaagaagga aaagtgaaac aagtagctac accaacagat acatttgata
     2701 cagatatggt cattttatgt gtgggcttcc gtccaaatac aaaactgatc gaaggaaaag
     2761 tagatacact gccaaacggg gcaatcaaag tgaatgaata catgcagaca agtaatccag
     2821 acatttttgc agctggagac tctgcagtag tcaactacaa tccaagtggc acgcaaaact
     2881 atattccttt ggcaacaaat gccgttcgtc aaggtttgct tgtgggaaat aacttgacag
     2941 atcataaaat ggcgtatcgt ggtactcaag gaacttcagg actttaccta tttggctgga
     3001 cgatcggttc gacaggtgtg accaaagaaa gcgcaacttt gaacgatcta gaagtccaag
     3061 cgactgtatt tgaagataat tatcgtccag agttcatgcc aactactgaa aaagtaatga
     3121 tggagctagt ctatgaaaaa ggaacgaatc gtatcgtagg tgctcagttc atgtccaaat
     3181 acgacattac acaatcagca aataccatgt ctttagctgt tcaaaataaa atgactgtag
     3241 aagatctcgc actttcagat ttcttcttcc aaccacattt tgaccgccca tggaattact
     3301 tgaacctact tgcacaagca gcgctaggcg aaatcgaaac tgcacaataa agaaaaaggg
     3361 ttgtgacaca attttgtcac gaccctctgt ctttttttgt gaaaagtaca attagttgtc
     3421 tttcttcgaa ttttttgtca caataagcag caaagataaa gctgttacat aaaagaacaa
     3481 gcagctttat ttgattttga aaagaaaggt gagaaagaag atgaataaag aatattttgt
     3541 ccaacaagat gcatttttag aagattataa aagtgcttcg aagaaattaa cgatcaatat
     3601 tgatgagttg gcagatcaag tactctctca gttgaatgaa acgcaagagg aatattacac
     3661 gatgccagca aatgacgcca aagataatgt ttctcatcgt tttcctttca gtagacgcat
     3721 ctactcagat gaaaatgacg gcacattgaa tacagagtac acatatgaag gtcagccata
     3781 tgtgctagaa actgatgatg atctttaaag acagtttttg aaaaggccgc tcatccttaa
     3841 gtgatgacaa aaaatcatca caattaccga tgactgtctc tttactatct tttaatcaga
     3901 aaaaggggtt atgacaagct ttgtcaaccc ctttttttct tggtttcaga ttgggttttc
     3961 ctacaaaata tttttatctt tgttgaatag gaaacaaaaa aacaatataa tgaaagaaaa
     4021 agaaggtgta gaaatggata aaagacaact gctaatagaa gaatatctgg atttagctaa
     4081 tgagattatt catcgtaata aaccagaaat ggaaaaagaa tttgcaggat ttactctaaa
     4141 tgaactagaa gtgattgaac atatcgggaa aatccctgat cctaacgtga caaaattagc
     4201 gaatgctagt tacatgacta gaggagccat cagtaagcta acaaaaaaac tgatagctag
     4261 agggatcata aacacttatc aaagcgaaga gaataaaaaa gaaatctatt ttcaattgac
     4321 gccaatcgga caaaaaataa ggaatagaca cgagcaactc catcaaaaat gggtacagcg
     4381 agatgctact gtatttgaaa atatgtcaaa agaagaattt gacacagtat ttcgttttat
     4441 cggtcgatac agagaattta tacgaagtag caaatgaagc tactattttt tattgtagtg
     4501 ataataggca aaaatcataa gcaaaaatcc gaataccgtc ggaagaaatg gtgctgcagc
     4561 ataaagctgt cctgcgatta gcgggccgat gacgcgcgat agagattgta tactttgggt
     4621 accgcccatt acaagacctt gctggttatc tgagacagaa ttggatagtt ggccattgaa
     4681 tacaggagta aaaatagaat caccgaaacc ataacagata atcccaaata aaaacaaaat
     4741 cggcagtaga agaattccag ataatgtgat gaatagatag gcgaggattt cactgaacat
     4801 ccctattctt gtgatctgct gttctgaaaa ttttttgagc aatcgaggca taatgaacaa
     4861 ttgcgagaca gtatccaaga ttccaatcaa agagaagctt aaaccaacca acccagcctt
     4921 ccactgaaag gcgtcaatcg aaaattgaga aaagatagat tgaagagagc cagctgccaa
     4981 ccaaacagca aaacctgctg tcaataaagg aataacggat gaaatcttga ataattgttg
     5041 taattggtga aaaggtctta catgggagaa acttaaatct actgaacgtt tttttattgg
     5101 aaggctttct agcataaatg tgtagccata aacggcattt aagaaagtaa agagtgctcc
     5161 aataaatata ggaacagaat tccccaactc agctaataga ccccctataa taggacccag
     5221 cgttgttcct ataccgacta aagcacccat ccatccaaaa actttggttc tttcattagg
     5281 ttccgtgatg tcggcaaagt aagcatataa ggtggagatt tctcctgccg tcaatccttc
     5341 aatgatacga ccaaggaaca acatccatat cgaatttcct aaaccaaaaa gcaaatatcc
     5401 gatacttgat cctaataaac tgataataag gatcggatga cgcccaaaat gatcacttaa
     5461 gctaccgaga atgggggcag ataagaaggc agctagagca taaacagaca tgagcaaagt
     5521 gatatagaaa gcttgctgat gtatggagtg agaataaggc agcgttaaaa acggaagtac
     5581 aggactgacg atagtaaatc ctaatccagt gaataagaca gagacgtatc caaaaacttt
     5641 agaatgttta tttgtgaaac tgtacatgta aaaactcctt tatgcaataa tgttaacttg
     5701 gaaacaaaaa tagtgtatag taattttgtt tccttgtcaa cattctaagg aacagcgaaa
     5761 tctacttaat ttatttattc cgaaaagtga agatacgcat caaaaacatg aacaaacaaa
     5821 aatcaagtag acgacattgt aaatctgacc gatcagtgaa gtaaatagaa aagaaacctg
     5881 ttcttgcttc ccatgttttt tttacgtata ctgtgattga gcggaggaga aatcatgttg
     5941 aatttagaaa attacttaag cgctggacaa acagtcatat ctaatctttt acttaaaaat
     6001 tatcatagga tcggtctaca atctgaagaa tttttatttg ttctacagtt gcatatggca
     6061 cagcttgaag gagatacttt ccctgatttg cagatgattg ctatggatat gggaatcaaa
     6121 caagatcaga tttttcaaat actggatcgt ctcgtaacaa atggatttat caagatagaa
     6181 acgacgattg tcaacggtaa aaaagcagat cgatataatc tttaccccat ctatgatcta
     6241 ttaggtgagt atttaaaaac acaagaaaaa aaatacgaag aaaaaacaca agaaaaagaa
     6301 atccagtcag tgtatcaatt atttgaacaa gaatttggac gcccgctttc ttcgatcgag
     6361 ttccagcgga tcggacaatg gctagaagaa gaccattatc agccggaaat tttgaagcta
     6421 gcactgcggg aagccgtatt aaatcaggct tatagtttta attacgttga ccgcattttg
     6481 ctatcgtggg aaagaaaaaa tctacgtaca aaacaacaag tggaagaaga ccaaaaacga
     6541 agaaaacagc agcttcttca aagagaagta gaacagtcag ctcaacaaga agaattgccg
     6601 aaagtctcac tgaaaaattg gttggaggag tagcggaata tgttaagcaa acaaaaaaca
     6661 atggaagctc tagaaacgat gtatggaatg tttcccgaag cacatggaga actcaagcac
     6721 aataatccat ttgagttatt gattgcagtg atcttaagtg cccaggcgac agatgtatca
     6781 gtgaataaag caacgccaga tttgtttgcc tcttttccga cacccgatgc gttagcagaa
     6841 gcttcaatcg atgaaatcat tcttaaaata aaaacgattg gtttgtatcg aaataaagca
     6901 aaaaacatca aagcgtgtgc acagcagctg attgaacgtt tcgatgggca agtgccaacg
     6961 tcaagagaag aattgatgtc tcttcctggt gtaggcagaa agacagcaaa tgtcgtattg
     7021 ggggatgcat tcgggatacc agcaatcgca gtagataccc acgtggaacg tgtctcaaaa
     7081 cgcctgagga tctgcaaact agatgctacg gtcatggaag tagaagaaac actgatgcgg
     7141 aaagtaccac aagaattatg ggtaaagaca catcatacac tgattttttt tggtagatat
     7201 cattgcacgg caagaaatcc caagtgcgag gtatgtcctt tgctatcaat atgtcaagat
     7261 gggaaaaatc ggatgcgtct aaaagaaaag gcgctaaaaa agaaaccacg cctgtagacg
     7321 tggtttcttt aattgcaaat aaatgtatga attatcttgt tattatggag aaaagctgtt
     7381 tcgtttatct tttttgcatg aaaaagtaaa tgtacatact cagtagctag gatggtaact
     7441 tattacaatt tattgcgata aaaataaaag ttgttatttt tattgggaaa atacccgatg
     7501 tagaaaataa tgccttccaa tatacctata aaataagtcc agtattccaa aggattatat
     7561 aaataagtga cgtatctatc taaaggtgta ataaaaatga taagtgataa taaaaaaata
     7621 ccatttataa ctaaacataa actaatggat ttgggcggtt tcaggctcat cagaaaaata
     7681 tagattctgg tgaacaacaa ccataaaaaa gtgagaatca ttgcatgaga gcttctttcc
     7741 ataaattttc ctttaagagt agtgcttaaa agtacagaaa aaataataaa tgcaaggata
     7801 ggagcaatta aagtaaattt atttaataat aaacaaaatt tttcagcttt tttattcttg
     7861 gaataacgag gtattgtttt cgataaaaaa agatggtgca gacaaattat gataattaag
     7921 catactatca gataactcaa aatgaagcct tctttcaaaa aattattcaa aaccatatat
     7981 tgtatttttt atttgataat aacaatggga ttattaagaa gtggcactaa ataaaagact
     8041 agtgtgtatt tagccgattt aattataaac aagtaaatgg ataaagtata tgtaatgata
     8101 aaagaaaaat ggattttcta atttttaagc taaatgttag atcacacatg tatatgctgg
     8161 atagtcttat aaaaaatcat gtaatacagc ttggtacatg atttttattt gtagctgttt
     8221 tttacataga cacaaaaaag aaaccacgct tgtagacgtg gtttcttttt tactatctgt
     8281 ttccagaagc tgaggtgctg ctggatggtg tatggtcatt tgcagcatcc gctccgctag
     8341 ttgctggctc actggaagaa gcaggaggag cagatgaaga cggtgtcgag ctttcttcgg
     8401 atgaagaaga aggaaccgtt gttgaagacg ctggctcgct tgtttctgct gtcgtgcttt
     8461 cttttgagga ctcagcagtt gattcgcttt gactagtaga gctagagctt tgagtcgttg
     8521 tctctgttgt tgagcttcca ggagtctgga catagctgga agatggaata gttgttgatg
     8581 gtgtaattgc attcgatcta gctgtatatt gatctttgta gtacagttca ccgcccacac
     8641 gaattaatcc gcttggcatc tcccagtctg tatttgtcac gttagctgaa acatactgca
     8701 taagctcgcg ataaacatca gaggctacgt gtgacgattc tgaagtgaca ggtgtcattt
     8761 ttttattgta acctgtccac acggaaatcg aataatttgg cgtatagccc gcaaatagga
     8821 tatctggata caccccagaa gaaataccaa gttttgcata ctcgtcatct gtgtaattgg
     8881 atgttccggt cttaccggct tgatataacc cagcgatttg cgcattcgta ccagttcctt
     8941 cagtgatcgt atcttttaaa atgtctgtga tcatataagc tgtttctgga gacatggctg
     9001 tttttccatc tggctcataa gtttcttctg ttccgtcttg gaagacgatt ttattaacat
     9061 attgaggttt gtaataagtc cctccattgg cgaaagccgc ataggctgct gccattttta
     9121 aggaagaagc tccgtatttt gtcccatctt gttcttccgt attactagag atcgcattcg
     9181 attgatggat cgtactgtat tcgatcccaa gattttttaa gaaagaagcc actttatctg
     9241 aaccgacttc attgaataat ttgactgctg gaacattacg ggataagtaa agtgcttggc
     9301 gtaaagtaat ggtgcccata tattgattat cccagtttcc tacaggagtc gaagtccctt
     9361 catagttata cggtgcgtca gtaatagttt ttccagtaga atatttcaaa tattcaaaag
     9421 ctggtccgta atctgtgaca ggtttcatcg tagaaccaaa atcacgggaa gtattcactg
     9481 ctaagttgtt gcctaaagtt acgtcttctg cgatgtgacg tccgccaatc tgggctttta
     9541 ctttcccggt attggtgtcg ataagggtgg aggcaacttg catctcgtcg tctgggtaag
     9601 agacatactg atccgtgttg acgatatcat atagtttctt ttgggcgtcc agatccaaat
     9661 tcgtataaat ctctaaaccg tctgtgtaga cattcttatc tgttttttct tgtacttcat
     9721 tgatgacttc tttgacataa ttatcgacga tcttagtatt gtcatcggat tgagttagtt
     9781 cttgcagacc atccgttacc ggtacattaa cagcttgatc atattctgtt tgagagattt
     9841 tttcgttttg aagcatcgta tacaaaacag tatctcgtct tttcttcgcc tgatctggat
     9901 aaacataagg atcataggcg gaaggggctt gaggcatccc agcaagcaat gctgtttgcg
     9961 gtaaagaaag ttctgataat ttcttaccaa agtacatctc agaagctgtc tccatcccgt
    10021 acaagccgtt tgacatatac actttattta cgtagtaggt caagatctct tgtttcgatt
    10081 ttttttgttc caatcttaca gccatccacg cttcttgggc cttgcgtttc agagtctgat
    10141 cctcggcact ggtggagaag aaggaaagtt tgatcaattg ctgtgtcaaa gtacttccgc
    10201 cttgcagtcc gccagaggta aagttagaga gggcagaacc gatgatccga atagggtcaa
    10261 ccccgatgtg tttataaaaa cggcgatctt ctaccgacac gatcgcatct tctaatgttt
    10321 tcggtaattc attcgcagaa attttttcac gcttttctgc gcctaaatct tcgaatagtt
    10381 cgccatcttg tgtatatagt ttggaagata cggtagcgtc taatttttta tccgtcaatt
    10441 cgggcgcatc ttttgcgtaa taccagaaaa gtcctacacc tgctaaaaag aggatacaga
    10501 aaaatgagag tattcctaaa aggatcttga taaataatcc ttttttatgt gttccagagg
    10561 actttccaga acctttgcca gaattcttct tcacactctt tttaggagta ggctgtttct
    10621 gtcgtctaga gcttctagtt tgttcatttg ccattcttgc tttctccttc aatagataat
    10681 gttgataaat agaagtcaac cgcgtccaaa taaggaatcc gcggagaaat accagttttg
    10741 atctctattc ctagttcttc gatcaaagat aaaggtagtg atttgcgtcc tttttccttt
    10801 tgggcgtccc agtaagcaat caaatgaaca ctattcaaat aaaaacagcg cttcaaagac
    10861 gaaaaccata acaagacaaa gcagacccca ttttgttcga ggcatgcttt catatgttcg
    10921 atttgatggg catggaagtt tttaaaggga aaagatgttt tgttcttggt ttcttttgct
    10981 tcaaagtcca agtaaaagcc tcgatagacg ccattatagt ctgtagttga ggcttgggta
    11041 aagtaggctt ccttgatcac agcagcactt ctcttaggat agtctacttt cacgatttgg
    11101 ataggggtag gctttttatg gataaccgcc aacccgcggg aaagataata tttattactt
    11161 tcattgattg cttcttcaaa gcgcatcccc cgattgccga attcagtgat ctgatttctt
    11221 ttttcttgaa ttttttcgac gggagaggca ttcttataat aaggttggcc atttggatag
    11281 cgcaatacca tctttaatca cactcctagg ccacattata gcaaaaaagc ggatagaaag
    11341 aaaaggaatc tgagatggat aagtcaaaag taatctatgt gtctgggtat cgaagtttcg
    11401 aactcggtgt ttttaaagaa aatgatccta aaatccaagt tgttaaaaat gttttaaaaa
    11461 aagaactcca tcagttagca gaagaagggc tggaatgggt acttgtcagt gggaatttgg
    11521 gcgtcgaact atgggctgtg caaatagtag cggaattgaa agaagaatat ccggaactat
    11581 ctcttggtat tttgtatcct ttttctgatt ttggtaataa ctggaatgaa gggaaccaag
    11641 aaaaaaaaca attagcagaa caattagcag attatgtcga agctgttagc catcaaccct
    11701 accaatcacc tagtcagcta aagaatcaca ctcgttttat acttgagcat acagtgggct
    11761 gtctgctgat ctatgatgaa gaattccctg gaaaaacgaa gtattttttt gaagatgcac
    11821 agaattacca agcagatcat ccctacgaaa ttcggctgat cagtatggac gatcttcaaa
    11881 attttagtga ataatcgata ttgtgtttga tttatcaact tttttcctat acaatgaaaa
    11941 aggtagaaat gttattacgt aaatgaaaac tagaggtgta aatatggcga atttggttta
    12001 tagtcctaaa gacattttac aacaagaatt caaaacaaaa atgcgcggct atgatcccgt
    12061 tgaagttgat gaattcttag acaatatcat caaagattat gaagcttaca gcaaagaact
    12121 ccttgcttta caagaagaaa acgatcgatt gagtgcaaaa gtagctcaat tatctaaaac
    12181 tcaaggagca gctcaaacac gcgtgcaaca aacagaggca ccaaagagcg cagcagtgac
    12241 caattttgat atcttaaaac gcttgtcaaa tcttgaacgt gaagtatttg gtaaaaagct
    12301 tgatcaacaa gcaagtgcag tcaaaccagc acaacctaat ccaaataact acacaaatgc
    12361 agacacaagc ttagatgata atgaaaaaac acgtcaattt taatttttga ttaatgaatt
    12421 tgcggttttc gggtaatcgc ggtctgactt gatcaggctg aggaaagtcc atgctcgcac
    12481 aggctgtgat gcctgtagtg ttcgtgctta gcgaaaccat aagctaaggt actctttgga
    12541 gtaacggcag gaaaacaagc taaggcttcg gctatgctta agtatccttg aaagtgccac
    12601 agtgacgaag cggctgggga aacccatccg gtggaacgcg gtaaacccct cgagcgagca
    12661 acccaaacaa tggtaggggc gctttttgtc tggaagaaga acaggacaaa aaggcagtat
    12721 aactgcagat agatggttac cgctttgttt tttctccctg gaaaagcaaa gtacagaaca
    12781 tggcttatag aaaaccgcaa acatcaggga attaggtcgt gacaaaagta atgcgttata
    12841 agaaacaaga aaaacatttg aaagctattt ttcaatactt cagatgaatc gttcttatta
    12901 caaaacaaac ttttgtatca ccggttattc ggaatttgag taaaagtgtg gggtaggact
    12961 gatgtcccac ctcctttttt tataaataag gagattgtgt atggaaaaaa acaggaagtt
    13021 caacctcgtc gcaactgcgg caagcgggct agaagcactg gttggtaaag aattaagaga
    13081 tcttggaatc gaatgccaag ttgagaacgg acgtgcacgt tttgaaggaa caatggaaac
    13141 gatcgctaca gctaatttat ggttacgtac agcagatcga gtaaaaatcg tggttgggga
    13201 attcgatgcg tatacgtttg atgaattgtt tgaaaacgta aaagcattgc cttgggaaga
    13261 ttttcttcca ctagatgcag cttttcctgt agctggaaaa tcgatcaagt cgaaactata
    13321 tagcacacct gattgccaag cgatcacaaa aaaagcaatc gttgaacgtc tccgtaccta
    13381 ttatcaccgt ccagcttctg taccactgac ggaaactggc gcacattttc agttggaagt
    13441 agctttgctg aaagaccatg tgatggtaac tctggatacg acaggaccaa gtttattcaa
    13501 acgtggttat cgcttagaaa aaggtggagc accattgaaa gaaaacatgg cagcagcact
    13561 tattatgttg acaaattggc gaaaagaccg tccattttat gatcctgtat gtggttcagg
    13621 tacgctttgt attgaagcag ccttaatagg ccataatatc gcaccaggat tcaatcgtga
    13681 gtttgcttgc gaatcttggg attggttcag tcaagaaatc atggaaaatg ttcgatcagc
    13741 agccgaagaa aaagcagatt atgatattga attagatatt actggttcag atatcaatgg
    13801 acggatgatt gaaattgcca aagccaatgc agaagaaatc ggattaggct cttcgattac
    13861 ctttaagcaa caagcagtca aagacttcaa aacggataaa gaatacgggg tcatcgtggc
    13921 taatccgcct tacggagaac gtctaggaga agaagaaact gttcggaaat tatataaaga
    13981 aatgggcgat gtattccgtc cattaaaaac atggagtaaa tatatcttga ctagcgactt
    14041 agcgtttgag gaattttacg gacaaaaagc aaccaaaaaa agaaaattgt acaatggtgc
    14101 attgcgtacg gatctattcc agtattgggg aactcgtccg cctagaaaaa aagagaaaga
    14161 cgaataatct tactaattga ttcattcaat tggatgtttg gaggaatagg gaatgaaaga
    14221 aaaagagttt ttacaagaag taaaagaaat caatcttcta caacaagctt taggaatcct
    14281 cgattgggat acacaaacag gtatgcctga aaaagctagt gcataccgaa gtgaagtaga
    14341 cagctatctt tacagcattt atttttcaaa aaaaatcggt ccaaaaatca aagaagccat
    14401 tcgctatttt tctgaacatc cggaagaatt gtcggaagtt ggaactgccg tttttgccaa
    14461 agtaaaagaa gagtatgatt tggaacatcg cgtaccggaa gatcttatga gaaaatatac
    14521 agctgccgtt tcttcagcac acggacaatg gcaaaaagct agagaaacac aacaattttc
    14581 tgattttcaa cacgcattga atcaaaatat tgaattaaca aaacagttga taccttactg
    14641 gagaaaagat gaaaagacga attatgatgt tttgctgaat caatacgaac ccgggatgac
    14701 tgtcgaaatc cttgataagg tatttgatca gcttaaagaa ggaattcttt cgatccgccg
    14761 tacgctccaa gaaaaaggga ctgaacctga aacagacttt ttaaatcgga gaatgacgaa
    14821 aaaacaacag aagagatttg tagtgaaagt aatcgaacaa cttggttatg attttagtcg
    14881 tggtcgttta gatgacactg tccacccatt tatgactgga attaatccga atgatgcacg
    14941 aatcacgaca cgatggaacg aaacagattt caaaatggct gtttttggag tgatccacga
    15001 ggctggtcat ggtatgtatg aacaagacat cgatgataaa tatgcgtata caccggttta
    15061 tgaaggtaca tcaatgggta tccatgaatc acaatcgttg tttaacgaga tcattattgg
    15121 aagtagtcgc agcttctgga aaaagcaata tcctttcttt caagaatgtg cagaaggaac
    15181 attcgatgat attccttttg acaaatttta tcgttcattg aaccatacaa aatcaagttt
    15241 ggttcgtatc gaggcagaca gtttgactta ccctctccat atcatcattc gttatgaaat
    15301 cgaaaaaatg attttcaatg aaggggtaga tgttgctgaa ctacctgaaa tatggaatca
    15361 aaaatatgaa gagtatctgg gaatacgacc aacaaatgat gtggaaggca tcctacaaga
    15421 cgttcattgg tcaggtgcaa gctttggtta ttttccctct tatgcattag ggtacatgta
    15481 tgcggcacaa ttacttcatt ctttgcagca agaaatagat gtggaaaatg ttctagcgtc
    15541 agacgattat tctccaatca aaaactggat gtcagagcat atccatcaat atggtgcatc
    15601 tagaaaacca aatcaattaa tcatggatgc aacacatgaa ccgcttaatc cgcaatacct
    15661 gatcgactat atgaaagacc tgtattttaa tgtatatcag gtaaaataaa atacaattta
    15721 caaagatagc tgaaattcat ctaatctata gatgttttca gctatttact taagaaagaa
    15781 gtggaacgaa tggataaatt acaagtgatc gctgattata gtatggacca attagcgcat
    15841 gatcaaacag gacatgggag cgatcatacc aaaagagttg tcaagttagc tgaaaaaatt
    15901 ttggagacgg aaccgcaggc agaccgcttt gtgacgcttg cagcagctta cctacatgat
    15961 acgattgatg ataaagtcgt taaaaatgag aacgaggcaa agcaacagct tcgtgtattc
    16021 cttcgctctt tgccaatagt agaggaacag atctcgatga ttttttccat tatcgaaaat
    16081 atgtcctttt ctaaaaatct ctctgaagcg gccgaactat ctctggaagg taagatcgtt
    16141 caagacgctg atcgtatcga agcattagga gcaatcggca ttttgcgtac tgcttatttc
    16201 ggcggtggac atgggcaccc gatttttgat cctgaactgt atccgcaaac attcaaggac
    16261 aaagaaaatt accgaaaagg cacgacagtg atcaatcatt tttatgaaaa actgttcttg
    16321 ctgtctgata aaatgaatac tgattacgga tatgaagaag ccaaacgaag agaaaccttc
    16381 atgcgtgaat tcttagaaga attttttctg gaatggtcta ttgacgatga aaattttact
    16441 ccagacaatt ggatcaaaaa taacaaaaaa tgatggaggt tgtgacagaa gtggtcagct
    16501 ccaagatatt tcggatcatt ttccgtaaaa gttacttctg gaacactgtt taccaagagg
    16561 tcgtgagcct gccgttcagc tccgagtcac aaggaacaat ttcaaaaaat agcttctcgt
    16621 gtttgatgaa tattgtaact tgtgattcgg aattggcagg agaacaccgt ttattcggaa
    16681 gaataggact gtgacaagac ttttgtcaca gtcctttttt cgaattcaac aagtaaaact
    16741 tttaagaaat attcagagag taaaattaaa aattgctgat aaacgaagat ggaaatttta
    16801 tgtattttta ttggtctatg caataaataa attaaatatt cagaatacaa ttgattttaa
    16861 cgaaagggct tctatcaatg gttgtgttgt atttatctgc ccaggtagag taaaatagat
    16921 cattatctaa aaggtaattg ttcatactat ataagtcatt tgaaagtaaa aagatactgt
    16981 aaataaaaaa tgtggttaaa taattctcat aatcagtgta agcgttatca aaaatatagc
    17041 atacttgctt tgtagatgaa tgacacgata tatgtttggt atgttctgca agacagatga
    17101 atatggaggt ggagacaatg tcttccaaag aactaacaat gtatttagag aaagaattgg
    17161 atcaactgaa agaaaagggg ttatacaata cgatcgacat actagaaagt gaaaatggtg
    17221 cttgtatcat cgtagacgga aaaaagatga tcaatctagc atccaacaat tatcttggat
    17281 ttgccaatcg cgaagaattg aaaaaagcat gtattgaagc aaccgaaact tatggtgtag
    17341 gagcaggagc agtccgaacg atcaatggtt cgctgaaaat ccatcagcaa ttagaagaaa
    17401 aaatcgcaga attcaaaggg acagaagcag caatcgcctt tcaatctgga ttcaactgca
    17461 atatgggcgc tatctctgca gtaatgacaa aagaagatgc tatcttatcg gatgaattaa
    17521 accatgcatc tattattgac ggttgccgct tatccggagc aaaaatcatc cgaattaaac
    17581 atcaagatat gaaagacctt gagaaaaaag caaaggaagc gatagaaagt aagaaatata
    17641 aaaaaatcat gtatatcaca gatggtgttt tctccatgga tggagacatt gcacgattgc
    17701 cggaaattat tccgattgtt gaaaaatatg gactgatcac ctacgtcgat gatgcgcacg
    17761 gctcaggcgt aactggaaaa ggtgcaggaa ccgtcaagca ttttggatta agcgacaaaa
    17821 tcgatatgca aatgggcacg ttatcgaaag ctataggtgt tgttgggggt tatgtagctg
    17881 gatcgaaaac actaatcgac tggttgaaag ctagaagtcg gccattccta ttttctactt
    17941 cgctaactcc aggtgcagct gcagctgcat tggcttcgat tactttgatg caagaacatc
    18001 cggaacttgt cgaaaaagtt tgggaaaatg ctaattattt taaagaagaa ttgaaaaaag
    18061 taggctataa catcggtatg tctgaaacac ctattactcc agtcattttg ggagacgaaa
    18121 aagtgactca gactttctct aagaagctga tcgaacatgg gatttatgct aaaccaatcg
    18181 tttatccaac tgtgcctctt gggacaggca ggatcagaaa tatgccgact gcggaacata
    18241 cgagggaaat gcttgatgaa gcagtagcag tttatcaaaa aataggaaaa gaaatggaaa
    18301 ttatttaact aaatttagtt ttttcgtcta tttaaaatta gagaacatgt tcacgcatat
    18361 attgttaatc atctgaagat agtagtaaaa aagatcaggg aggatcatca tgaaaaaagt
    18421 attggtgaca ggatgtttag gacaaattgg ttcagagttg atcacacggc tacgtcaaga
    18481 actaggcagt gaaaatgtca ttgcgacaga tatacgcatg cctgaagtca ttgagaaaaa
    18541 cgatatcttt gagatcctag atgtaatgga ttacgaaaaa atgcgcagca tagcagaaca
    18601 atatcaagtg gacacattga ttcatttggc tgctcttttg tcagctgttg cagaagcaaa
    18661 accacaatta gcctggaatt tgaacgtgac tgggctggtc aatgcattgg aagtcgctag
    18721 agaattccag ctgaaatttt ttacgccaag ttcaatcggc gcgtttggtc caaatactcc
    18781 aaaagatcat accccacaag atactcttca gcgtcctaca accatgtatg gggtaacgaa
    18841 ggtagctgga gaactactat gtgattatta ttatgtgaaa tatggcgtag atactcgtgg
    18901 tgtccgtttc cctggattga tttcttatgc aaccttgcca ggaggcggta cgacagacta
    18961 cgcagtcgat atttattatt cagcaatcaa agaaggaaag tacactagtt tcattgatca
    19021 aggtacatca atggatatga tgtatatgcc agatgcgatc gatgccatta taaaactcat
    19081 gaatgcagat cctgatcgat tggttcatcg aaatgccttc aatatatcgg cgatgtcttt
    19141 tgacccggaa gagatcaaag catctattca aaaaatcata ccagattttg aaatggatta
    19201 tgatgtggat cctgtacgtc agtcaatagc agaatcttgg ccaaattcac tagatgtttc
    19261 ttgtgcgcaa gaggaatggg gcttttcgcc gaaatacgac ttagatgtga tgacaaagga
    19321 tatgttggaa aaactgaaag aaaaattggt agagacggta taaaacaaga accacatcca
    19381 aaaagttttt tatacttttg ggattggcta tggtatgaaa ggggacaagg gatggaagaa
    19441 tatcaagcca cgccagtaaa agaagtaaaa atagaaaatg aattaaaacg tacgatggga
    19501 ttttttactg ctttatcgac tgttatgggc acagtgatcg gtgcaggggt attttttaaa
    19561 gccgcaagcg tagcagaagt tacaggatcc gccagtttgc atatgttttc ttggtttctc
    19621 ggtggtatga tttctgtctg tgcaggacta acaggagctg aactggcagc tgctattcca
    19681 gaaacaggag ggatgattaa atatatcgaa cggatttacg gaaatacagc agctttttta
    19741 ttgggctggg cgcaagtcgt gatttatttt ccagcaaatg tagcagcctt gtcgatcatt
    19801 ttcggtacac agttcgtcaa tctatttggt ctttcccagt caatgattgt tcccgtagct
    19861 gttacagctg ctgtatcgat cctgttgatc aattttttag gttctaaagc tggaggggct
    19921 tttcagtcga ttacgcttgt ctgcaagctt attcctttgt ttgtgatcgt cattttcggt
    19981 ttgttccgac aagaaggagt agacttccaa ctgtttccga tccaagcagg agaaaatctt
    20041 tcatttttct cagccttggg agcgggcttg ctagcaacga tgttcgcata cgacggttgg
    20101 atacacgtag gaaatatttc gggagaattg aaaaagccgg cgaaagattt gccaaaagca
    20161 atttctttag gaatcatcgg aatcatgatc gtttatttat tagtaaatgc ggtgttctta
    20221 agaaccgcat ctatcgacgg agtcgcagga aacagcaatg cggcaagtga cgttgcaaaa
    20281 atgatttttg gcggcttcgg tggaagactg gtcacagttg gtatcttgat ttctgtttat
    20341 ggaaccatca atggctatac ccttactgga atgcgtctcc cttatgttat ggcaaaagaa
    20401 aacaacctgc cttttagcaa gctctttgct aaacttcatg ataaaactaa agttcctgta
    20461 gccgcaggta tcttagagct agtcatcgct attggcatga tgatgatcgg tggttttgat
    20521 acactaacgg atatgctgat ctttgtcatt tggatttttt atacgatggt ctttgttggt
    20581 gtcattcttc ttcgtaaaaa agaacctgat ttgtttcgac catacaaagt tccaatgtat
    20641 ccgtttattc cactagtagc aatcattgga gggactttta tcgtatcaag cacgcttatc
    20701 actcagacct ttttagcttc gatggggata gtattgacac ttgctggtat cccgatttat
    20761 ctctatttaa aacgtagata gctaaaacat tcgaatttta ttagaactgc acttctctgc
    20821 caaacaaaat attttattta aatgaggagt acgtggaaga aatgtcaaaa gtactcgtta
    20881 attttgatca cgtaaatgtc gttttgtcta cgatgaaata gcaaagtaaa agacagaaat
    20941 cgggctcaac cgatttctgt cttttacttt gatttgcgta actgaactat tcggcgtacg
    21001 ccgcgataaa tatttaataa aaccaagcaa ccagaaatga aaatgggaag ccaaatcaga
    21061 tagacagggt agccaagcac tttagacaaa gcatgtggag tcattttatc catttcaaga
    21121 agtgcttgct gccaagtctg aagattgaag actagcatga aacccgaaat aatcaggaga
    21181 ataaatccta aataatgaat tgtagttctt tttcttacat aagcgatcgt agcataaagg
    21241 aacagtaaaa aaataggtac gccaaaaaca aagtacatat tcagcatctc gacaccccct
    21301 ttgtgtttat cttactttac tttgaaagaa atgagaaata atagcctcgt tacttgcttg
    21361 aaacagcaaa ggactgctaa gataagagag atacaaagaa tcaaggagga gtcatatggc
    21421 aagttatatc gaaccgattc gttttgcgct gattgttttt ccatttttag ccttagcgat
    21481 ctcatctgtt ttttttattt atgaatatcg aaagtatgga acatttctag taacaagggc
    21541 agttattttg tattctttcg ttttttattt attgtgtgcg tattttttgg tgatcttacc
    21601 acttccggca aaggagacgg ttgcccaaat gacagggcca aagatggagc tgcatttatt
    21661 tgcttcatgg caacatttca gagacaacac ggtattggtc ttgtctgaac ctagtaccta
    21721 cctgccggca atgaagcaga gtgtattttt ggaaccagct tttaatgttt tattactcat
    21781 accatttggc atttatttaa gatattattt ccggctttct tttatgaaaa cgatgattgc
    21841 tagtttctgc ctttctctat tttttgaatt gacgcagcta agtggacttt attttatcta
    21901 cccaagacca taccgcttat ttgatgtgaa tgatttagtg acaaatacat tgggtggaat
    21961 cattggtttt gtcgttacgc cgttatttac atttatgctt cctacaagaa gacgaatgga
    22021 tgaactttct tatgaaaaag gaaagactgt ctcattgact cgacgcttgg tcgcttattt
    22081 gatcgactgg acatttttat ctcttattaa tttggtagcg gcgattttct ttaaaattgc
    22141 gttcgattca ggggcagtta cttctcatat ctggtggctt ttattagaag taggggtata
    22201 ctttatgatt gtaccgttta taaccaatgg atggacactt ggcaaaaaaa ttgtgcgtat
    22261 ccgtttggtg gaagaagacc gcgaacgaat ttctttaaaa gcattgatga tccgctacgg
    22321 gtatctgtac tttctttttt atggtttaag ctggttgggg cagttgcttc agcaaatcat
    22381 gaattcgaca acgaatacgg tgttgcagat gagtgcagta ttcatttctc tcggtgtctt
    22441 gttactacaa ggtattttta ttttaaatat cttgctatca tttttgagaa aaaaacggat
    22501 tctgttttat gaaaaagcta gtcacacata tactgttagc acgattggcc aaacaaagga
    22561 tgatgattct cgaaattagc tgagcaaaaa cgctttgtct gtgttataat gccaaagtcg
    22621 tgataattta aagagaagag gtgcacgaat gaataatttt gatatattcc gcttcaaacc
    22681 gtttatcaat gaagcgttaa ccgcaaaggg cttcaaacag cccacagagg tccaggaacg
    22741 tttgattcct ttaattgcaa aaggaaaaaa tatcattggg caatctcaaa ctggtacagg
    22801 aaaaacacat acgtttttgt tgcctttgtt tgaaaaaatc aatgcagaaa aagaggaagt
    22861 acaagttgtt attacagctc caagtaggga actagctgca cagatctatg aagcagctac
    22921 acaaatcgct aaattttcta caccggagat ccgtgtctcg aattttgtcg gcggtacaga
    22981 caaacagcgt caattaaatc gtctgcatca ccaacagcca caggttgtag taggcacgcc
    23041 tggtagaata ttagacatga tgaatgaaca agcgctgaag attcacaccg catttgcatt
    23101 tgttgtcgat gaagcggata tgacattgga tatgggtttt ttaaatgaag tagaccaaat
    23161 tgcaagtcga ttaccagaaa agctgcagtt tttagttttt tctgccacta ttccagaaaa
    23221 acttcgtcca ttcttacgaa aatacatgga aaatccaatc attgaagaaa tcaaaccaaa
    23281 agcagttatt tctgaagaca ttgaaaattg gctgatttca acaaaaggta aagatgagaa
    23341 tcaaatgatt tatcaactgc tgacaattgg tcatccttat ttagcaatcg tatttgccaa
    23401 tacaaaacag catgtggatg aaattgccga ttacttgaaa aaccaaggct tgaaagtagc
    23461 aaagattcat ggagacatca ccccaagaga gagaaaacga gtgatgcgac aagtacagaa
    23521 tctggagtat caatatgttg tagcgactga tttagctgct agagggatcg atatcgaagg
    23581 tgtctctcat gttattaatg cagaaattcc agaagatcta gacttcttta tccatcgtgt
    23641 cggacgtact ggacgtaatg gcttaaaagg aacggccatt acgttatatt cgccaaatga
    23701 tgagcaagcc attgatgcga tagaaaaatt gggcgtctca tttgaaccaa aagaaatcaa
    23761 aaacggggaa atcgtcaaaa catacgatcg taatagacgt gccaaacgag aaaaatcaaa
    23821 agatgtatta gatcccacgc tgattggtct tgtgaagaag aaaaagaaaa agatcaagcc
    23881 tggttataag aaaaaaatcg attgggcaat tgcagaaaaa aataaaaaag aacgcaaaat
    23941 cgaacgcaga cagcaaagcc gtactgctcg taaaaataag aaaaattcac ataaataaaa
    24001 aacaagaggt tgtgacaaaa ggcgtgtcac aatctcttgt ttttaagcta gacttttttt
    24061 cattccgata caaagtactt catcttcaat aaaaggttct gtgcaagtat gatacccttg
    24121 tttttcataa aaatctacag ccgtcatttc agctactaca taactagtct gacaaccttc
    24181 tgaaaccgcc cgtttttcag cagcttcaag caactgaccg cctaaccctt ttcctcggta
    24241 ttcttttgct acgcaaaatc gttccggctt gaagcaagta ggtgttttct tttcataacg
    24301 caaagtagct actggtcttt tttgatcaag aaatagataa taggtttgtt gcgggatatc
    24361 ttttccgtcg aattctagtt ctgcaggaat cccttgttct aatacaaaaa cttgatatct
    24421 caaaaagcag ctagctgcgc gtatccattc atccgctcca actatttttt tcatcatatt
    24481 cctccttgtc atgaatagca gagatgtatt gattccttta ttcttatcgt accaaaaatc
    24541 gtggagtatg accaaaagga aatgaaaata aaaattgaga tattgacagt gatcaataga
    24601 atgcgtatac taaataagta cgaaaaggat atgatttgtt ttttaagact cacagaaaat
    24661 tctttcttgg ctgaaaaaag aatagtcact aatcaaattg ctcccttttt ctattttggt
    24721 agaaataccg acgcagctca gcgttatcga gtttaagagg taatgattac acatcattgc
    24781 aatcaaggtg gtaccgcgag ttttcgtcct tggctgtgat ggtgtttttt tgtatttaat
    24841 ttatagaaag caggtaatga catgaaacaa ttaagtagtg cacaagttcg acaaatgttt
    24901 cttgatttct tccaatctaa agaacatacg attgaaccta gtgcgtcttt gatccccgtg
    24961 aacgatccaa ccttattgtg gatcaactct ggtgttgcaa cattgaaaaa atattttgat
    25021 ggttcagttg tgccagaaaa tccaagaatc acaaatgccc aaaaatctat tcgaacaaat
    25081 gatatcgaaa atgtcggtaa aacagcacgg caccatacga tgtttgagat gctgggtaat
    25141 ttttcgattg gtgactattt caaaaatgaa gccatccact gggcatggga atttttgact
    25201 gatccaaaat ggatggcatt cgatccagaa aaactttatg taacagttta tccaaaagat
    25261 acagaagcaa aacgcatctg gcatgaagaa gttggcctgc cactagatca cattattgat
    25321 gtagaagaca acttctggga tatcggtgca ggcccatgtg gtccggatac ggaaattttc
    25381 tatgaccgtg gagaagctta taacgattta gcagaagacg atcctgaaaa ctatccagga
    25441 ggagaaaatg aacgttattt agaaatctgg aacttagtat tttcagaatt caaccataag
    25501 cctgataaca catttgaacc acttcctcat aaaaacattg atacggggat gggattggaa
    25561 cgcatggtct caatcgttca agatgcgtca acgaactttg agacagactt gtttatgcct
    25621 attatccacg ccgtagaaaa gctaagcaaa caagtaaaat atggtgaaaa cccagtaaca
    25681 gatatttctt acaaagtaat cgcagatcat attcgcgccc tttcatttgc tattggcgac
    25741 ggtgcattgc catcgaatga agggagaggg tatgtcttac gccgtttgct tcgtcgtgct
    25801 gtcatgcatg ggaaaaaatt aggtattgaa caagcattct tatatcgttt agtccctgtt
    25861 gttggggaaa tcatggtaag ttattatcct gaagtacttc aacaaaaaga atttattgaa
    25921 aaagttatcc gtacagaaga agaacgtttc aatgaaacaa tcaatgaagg tttggaaatc
    25981 ttaaatcaag tgatccaaga agtaaaaaac gaaaacggga cgactctagc aggaaaagac
    26041 atcttcaaac tatacgacac atatggcttc ccggtagaat taacggaaga ggtggcagaa
    26101 gatgaaggac tgaaagttga tcatgctggt tttgaaaaag aaatggatgc acaacgcgaa
    26161 cgtgctcgct ctgcccgcag tactgaaaaa tcaatggggg tacaatctgc tttattgaca
    26221 gatatcaaag tagaaagtaa attcattgga tacacagaac aagaatcaga tagtcaatta
    26281 ttggtcatcg ttaaaggtga gtctcttttg aatgaagtcg cagaaggtga agctcaaatg
    26341 atctttgatc aaacaccttt ctatgcagaa atgggtgggc aagtagcgga tcaaggatgg
    26401 atcatgaatg aagtaggcga aatcgtagca gttgttacag atgttcaaaa agcgcctaat
    26461 ggtcaattta tgcacaccgt agaagtaaaa gcaccaatga gtgaaggaca aacctatcat
    26521 ctattgatcg atcaatcgat gcgcaatcgg atcatcaaaa accatacagc aacccatcta
    26581 ctgcacaagg cattgaaaga agtacttggc gagcatgcaa atcaagctgg ttctttagtc
    26641 gctcctggac atttacgatt cgactttacc cactttggtc aaatcacttc agatgaatta
    26701 gctgaaatgg aaagaatcgt caacgaaaaa atctgggaag ctatcccagt tgaaacaatt
    26761 gaaacagata tcgatacagc caaaaacatg ggtgcaatgg ctttgtttgg tgaaaaatac
    26821 ggacatgacg ttcgagtagt aaatattggc ggctggtcaa tcgaactgtg cggaggcaca
    26881 catgtagcaa atacagaaaa catcggaatc ttcaaaatcg tttctgaatc aggaattggt
    26941 gcaggcgtgc gacgaatcga ggctgtaaca agtaaagaag cgtacgaact acttgaagaa
    27001 gaagaaaaac aactaaaaca agtagcaaca attgttaaat cacctcaatt gaaagaagtt
    27061 gtttcaaaag cggaacaatt gcaacagcaa gtaagagagc tacaaaagga aaatgaacaa
    27121 ttagctagca agttagcgaa tcaacaagct ggtgatgtat tcaaagatcc agaaacgatc
    27181 aatggaaaaa caatcattgc agcacaagta aaagtgaaag atatgaatca gctgcgtcaa
    27241 ttagctgacc aatggaaaca aaaaaatatt tcagatattc ttgttttagc aaacgaacaa
    27301 gaaggaaaag tcagtctgct agcggcaatg acgaaagaat caaatgaagc tggactaaaa
    27361 gctggcgact tgattaaagc aatcgcaccg aaagtaggcg gtggcggtgg tggacgtcca
    27421 gacatggcac aagctggcgg gaaaaatcct gctggtattc cagatgcact taaagctgcg
    27481 aaagaatggg ttgcgcaaca atagggcgtt tacgtttgac agaaaaacaa aagttcaaac
    27541 attgaacgaa acatgattat gggggcgaag acaaacaagt cttgccctca tacttttttc
    27601 aattggatgg cgcatctaat caaatggtcg gattcggatg gtctttagtt gacgaaagtg
    27661 acagaaattt ttacgattag tataaataaa aaggggtgaa aaaatgaata gtagaaataa
    27721 gacctttcga ctagtcttac gtgcgatctt gttagcaatc atcatcgtac aagcgatggt
    27781 tccttggctg gggtttattc cattaggatt cattagttta acaattatcc atatcacagt
    27841 aattattgct gcagtagtat taggcccaaa agatggcatg gtgattggct tgttttgggg
    27901 aatcgctaca attgttcgtg cctatgccat gccaacaacg ccatttgata cattagtgtt
    27961 cacgaatccg attatctcgg tagttcccag agtacttgtt ggcttagtag caggcttggt
    28021 tttccactgg atttatcaaa aaaataaatc aataacgatc agctcagcct ttgcaggggt
    28081 actgggttca ttggtcaata cagtcttagt gttaggattc atgggattat tttatacagg
    28141 tgcaacggca gatgcctatg gtgtagactc tgctctttta tttaaaacct tagcaggggt
    28201 tgcagcaatc aatgggatac cagaagcaat aggtgcggga atcataacac cattactagc
    28261 aaaagcgtta tttgcagcaa caccgttgaa accagaataa tgaccatctt ttaatagtaa
    28321 taggacgcac gatagataga aaaaggaaga gaggagagga aaacaatcgt cctctccatc
    28381 tttttacctg agcaacaagc aaactagaag gggtaaaaaa cttggctaag aaacaagaag
    28441 aaaaaaagaa acaaataccg caacagcgga caaaaaaagg agtactagcg ggtatcttag
    28501 gattggttac gaatctgatc ttgtttgtct ctaagctaat gatcgggctt ttttcaggaa
    28561 gtgtctccat tatggctgat gcagtgaaca gtctatcaga tactgcttca tccatattga
    28621 ctttgatcgg atttaaaatt gctgcaaagc cagcagatca ggaacatcct tatggacacg
    28681 aacgcttcga atatatcagt gggttatttg tttcgatcat cattacttat gtaggatttc
    28741 aatttttaga gtcttctgct gaaaaaatca tccatccaga aaatgtctct ttaacaccca
    28801 tcgtcttttt tgtcctaatc atttccatct ttttgaaatt tgcacaaggc aaaatgtatc
    28861 aggttattgc gcaatccatt gattctgaaa cattgagagc tacagcaaca gatagttata
    28921 atgatgtctt tactacactg gctgtattgc tttcagcagc aatcgaatgg gtaactggat
    28981 ggcgtattga tggatatata ggttttgctt tagcattata tatcctttat agtggattga
    29041 cgatgcttcg aaattttgta tacgaactat taggaagtcg cccaacgcca gcagagattg
    29101 aagaaatgga agagcattta aatgcttgcg atgatatact tggctatcat gatttattgg
    29161 tgcataacta tggacccaat aaacgctttg catcagtcca catcgaagta gatgaatcaa
    29221 tgaatttgaa tgtggctcat aagattattg atctgataga aaaagacttt aaaaagtctt
    29281 tggatgtgga acttgtctgt cacttggatc caatgcctgt tgataacgaa aaatactata
    29341 atatcttgcg gcagttaaag caaattcttc ttgaaacagg tacagggctt aatattcatg
    29401 attttagagt aattcatcaa ggaaaaacgc tgcaatttga tgtagtggtc cctgagaaat
    29461 tccagtttgt tgatacagaa ctagaaagaa tcttacgtag tcaaatagaa gaaaaaatcg
    29521 gagattacca attggaaatt acgtttgatc acaattatct tttatattaa atgagaaact
    29581 ataaaaagac tccttaaagt ttttaattta aagagtcttt ttttctttta attgtttatg
    29641 gagagcctga cgtgcaagat tatctgctcc tttatttttg ttttcgggca accattgcag
    29701 gatcaataaa gaaaattcgg atagaagttc ttggattctt tgaaggtagg gaaggaagag
    29761 ctcgttcttc gttgcgtttt tgtcgaccgt agaaactagt gttttgctgt ctgaaaaaca
    29821 gaaaatcgtt tcattctgta agtcgttttt ctttagaaat tctaaagttt ttaaaaagac
    29881 ttcgaactct gcttgatggt ttgtccctat agaaagcggg atagatagct gttcttgttt
    29941 accttgatag acaatcaaga ttccacctcc actaggacca gggttgcctt ttgtagaggc
    30001 atcaatgtat acttttaaca taaaaagaga ttctcctttt tgttcaaact aatgttatgg
    30061 taagattata tcattactga atcggtgaga ggttagagaa tgaaaaaaaa tattcgatgg
    30121 cagcctgaac tggcacatac gatcatctat tggtcattga ccttgatcat tctgtttttt
    30181 agtctgattc tttctttaga aaacacaggt ccttattgga aaagcaattt tgttttaggt
    30241 atttttcttg tttttctatt tctaggtttg cggcgttctt ttattttaaa atcaaactct
    30301 gtgattatac gttatgctgc tttttggaaa gaccgagaaa tatctgtcgg acagattcga
    30361 tctttgacgc caactaatac tggggtgcaa atgatgttgc aagatgagaa agccccatct
    30421 gttttcatga tgcgaaaaaa agatcaagta gtcctttttg atcattttga aaaaaacgga
    30481 cccaaatcag aatcaattcc ttatccttat acgaaaaaaa gaaaaagcta attttaaaaa
    30541 tcagaaccta aaaaaacgaa tttttacagg aaaagaaaag agtgagacgt acggttcatc
    30601 ccgtttagcg tctcactcta tttgtttatc tattcatgca tactagtatc ggtagtctga
    30661 acgttgcctt tcttgacatg ggcagcttgt gttcctcgat tcccttcgat gatctcaaat
    30721 tcgaccactt gattttcttc caaagttttg aatccctctt cttcaatcgc agtaaaatgt
    30781 acaaaaattt cttctgtgtc atcataactg ataaagccgt atcctttttt gttgtcaaac
    30841 cattttacaa ttcctgtggt caaagcactc acgacctttc taaagtctga tcatagcctt
    30901 cattataaag agtatttata agtacgtcaa ataaattaaa aacctgtaat tttatgtttt
    30961 ttttctgaat aaaaaaaggt ataattggca tatcttaaca aagaagatat tttgttgaat
    31021 aaagttcgtg aaaaggggta atcaaatgaa gaatgatctg caaatttcac aagaaacaga
    31081 gctagaaccg attgttgaag tggctagtaa attagatctt aaggaagacg atttggaact
    31141 gtatgggaaa tataaggcga aaatcaattt ttctggaatc aatcgatcaa aggataacgc
    31201 tgaggggcat ttgatcttag ttacttccat caatccaaca ccagctggcg aaggaaagtc
    31261 aacgatcact gtagggttag gagacgcgct caataaaatc aataaaaaat ctgttattgc
    31321 attgcgagaa ccctcacttg gtcctgtgat gggaatcaaa ggtggtgctg caggcggagg
    31381 atatgcacag gtattgccta tggaagatat caacttgcat tttactggtg acatgcatgc
    31441 tatcacaaca gctaataatg cattatctgc tcttttagat aatcatattc atcaaggaaa
    31501 tgaattgaac atcgatgccc gccgagtgat ttggaaacgg gtagtcgatc tcaatgatcg
    31561 tgaactgcgt aaagtaattg ttggcttggg tgggccaatc caaggtgttc caagagaaga
    31621 tgggtttgat atcacagttg ccagcgaaat catggctatc ttgtgtcttg cggcagacct
    31681 tgaagattta aaggctcgtc ttgcaaggat cgttgtcggc tatacatttg accgtcagcc
    31741 tgtgactgct ggagacttga aagcagaagg cgctctggca ttactgctga aagatgcaat
    31801 caagccgaat cttgtacaaa caatttacgg aacaccagct tttgtccacg ggggaccgtt
    31861 tgccaatatc gctcatggct gcaatagtat tttagctacc aagacagcat tgagattagc
    31921 agattacgtt gtcacagagg caggatttgg tgcagatctt ggcggagaga aatttttaga
    31981 tatcaaagta cctaacttga aaaaagcgcc ggatgctgtg gtgattgtcg ccactgtccg
    32041 tgcattgaaa atgcatggcg gaatgaaaaa agatgaactt aaaaatgaga atcttgatgc
    32101 tttgaaagta ggttttgcaa atttaaagcg ccatatacgt aatatggaac aatatcagct
    32161 acctgtgatc gtcgcaatca atgaattcgt aacagataca gacaatgaac tcacactgtt
    32221 ggagcacttg tgtgaaaatc aggggattct tgccaagaga gcgagtgtat gggcagatgg
    32281 agcagaaggc ggcgttgatt tagcaaaagc tgtagtacga ttgattgata gaaaagaagc
    32341 taattacaag ccattatacc gcctagaaga aacgatacaa gaaaagacag aaacaatcgt
    32401 caagaaaatt tacggaggaa atggtgttgt tttcagcaaa aaagcgcaaa aacaaataga
    32461 agagtttacg aagaatggat gggacaaact gccgatttgt atggcaaaaa cacagtattc
    32521 attttctgat gatccttcac tgctaggtgc accggaagat ttcaccatca cgatccgcga
    32581 aatcatccca aaattagggg caggattttt agtagccttg actggagatg ttatgacgat
    32641 gcctggtttg cctaaaaaac ctgctgcatt gaatatggac gtgacaaatg acggagaagt
    32701 gttgggattg ttttaagctt gattataatc taccatcgaa ggagctgtat tttgactaca
    32761 gcttcttttt ttagacgata gggaattaat tttgtttaca ctaggatcat tctttttctt
    32821 tattgtattt tgagctatac taaagcataa taggagggta tgatgaaaac gacatttata
    32881 agaaaaaccg gtttttacgg tatgggtagc tcgattcagc taagaatcaa caatgaaaaa
    32941 cgcagtgttc tcagtcatga acaaaagata acgcttgatc tggaagtgcc ctttacgatg
    33001 caggtcacct tttattggct aaaaagcccc gtttatacag tgaaagaagc aaagcctgct
    33061 tatgtgatca caatgaatta cttgattctt caaatctatc cgtttttatt tctagcaact
    33121 gggttggggg ccgttttcct acaaaattta tttttcagtt tttttgcagt tattgtgttg
    33181 attgcgttct ttttctatat aaaaaaccgg gcatatttga tcaaggagga aaattatggc
    33241 aaactctgat ctttttttaa tcagtttcaa tcgaatcgaa aaatggatga gagacgagat
    33301 gggaaatgca cgaaatatgg gatttaccga acttgtcaga cgcctagctc aaagaaaaca
    33361 attaatgatc agaaaatacg aagatgatct tttacagctt gctcagttaa ggaatgcgat
    33421 cgtccatgat cggatcgcag tcgattttgt cattgcagag ccaaatgatt ggacagtcaa
    33481 gcgaatccag ctgatcgaac aagaactgat tcagcctgaa accgtgctgc ctcgatttgc
    33541 aaaacgtgta acaggttttg aacaagatct tccgttactt gaactgttaa agatagtagc
    33601 agaaaaaagg tattcacaat ttccgttata caataaagga aaatttgtag cattgattac
    33661 tttacgtaat atcgggtttt ggctagcaaa agaaagccaa aaaggtccgg ttgatttaac
    33721 aaataaacga gcgttggatt tgatcatcca aaacggaaag tacacaaatt atcattttgt
    33781 tccagctaaa acacatattt acgaggttga agcgatgttt cgtgagcaag ggactttgga
    33841 agccgtactt atcactaaag atgggaatcc cgatggtaat ctgctcggga tcgtacgacc
    33901 tcgtgatatt tataaacaaa tagaaaagga ttgatttttt gttaattatt tattggatat
    33961 tcagcgcttt gctagtagga gtggatcagt tggtcaaatg gtggatcact gataatctag
    34021 cgcttggaga gacgaaaaat cttataccag gtattttgtc actgaatcat attcgaaaca
    34081 ctggagccgc atggagtatg ctagaaggga agatgtggtt ctttactata gtgacactca
    34141 ttgcagtcgt tgtgattctc acattgatga ttaaaaatcg tgaaaaaggt aatcgctggt
    34201 tcatgattgg attgagtttg attctagctg gtgcgattgg caattttatc gaccgtattc
    34261 gtcttggcta tgtagtagat atgttccaga cagattttat gagctttccg atttttaacg
    34321 tagcagatgt gacacttgta tgtggagtga tttgtatgtt aatttatatt attttagatg
    34381 aaaaggatca aagaaaaaaa tgacagaact taaaacgacg attcaccatg aatctggtag
    34441 gatcgataaa gtattgacta atttattcac cgattacagt cgttcgcaaa ttcagctgtg
    34501 gctgaaaaat ggagcggttt ctgtcaatgg acagccagtc aaagcaaatt acaaagtaaa
    34561 acaaggagac gagattactg tcttgatccc cgaaccagaa acattagatg tggtcccaga
    34621 aaatatcccg ttgacgatcg tttacgaaga tgaagatgta gcggtgataa acaaacctca
    34681 aggaatggtc gttcatcctt cagcaggtca tacgcatggc acaatggtca atgcgctgat
    34741 gtaccatatc aaggatcttt ctacgatcaa cggcgttatt cgtccaggta ttgttcaccg
    34801 aatcgacaaa gatacttccg gactgctaat ggttgccaaa aatgaccagg cacacgaatc
    34861 attagctcag caattaaaag ataagacctc tttgcgcaaa tatgttgctt tagtccatgg
    34921 agagattcct cacgaaaaag gaaccatcaa tgcgccaatc ggccgttcga aggaaaaccg
    34981 gaaaatgcag gcgataagag aagatgggaa gtcggctgtc acacatttta ctgtattgga
    35041 acgtttcgaa ggatttactc tggttgaatt aaaactagaa accggaagaa cacaccagat
    35101 ccgtgtgcat atgaagtata tcggttatcc gttagctgga gatccagtat acggaccgaa
    35161 gaaaactttg aaaggcaatg gtcagtttct ccatgcgcaa atgttaggtt ttacgcaccc
    35221 gactacaaac gaaaagatga tctttgaagc acctcttcca gaagtttttg aaaaaacttt
    35281 agaaaaatta agaaaaaaca ttgcatttta atttagataa cggtatagta attaacaacg
    35341 aaagcataaa acttaataga attcctttaa gtttagtccc gtgaggctaa gaagggtggg
    35401 agcaaggata cgtatggtgc gccataagta gattgctcat tgacatagta tagctatcag
    35461 tgtatcagta tacgctcagt ctaaacattc ctcctgtcct cttagggcag gagttttttt
    35521 atgcaaaaaa gtagggggaa tgaaaatgca agcaaaagaa gtagtagatc aggtaaccat
    35581 gaagcgagca ttgactcgaa ttacttatga gattatcgag agaaaccata gtatccaaga
    35641 tatcgtattg gtaggtatca aaacacgagg aatctacatt gcatcaagaa ttgccgaacg
    35701 cctgaagcag ctagaagata tcgatattcc tgtaggagaa ctggatatca ctttataccg
    35761 agatgacaaa aaagaaaatc cagaagaacc ggaacttcat tcttctgaca tcccagtttc
    35821 cttagaagga aaagaagtta ttttgattga tgatgttttg tatacaggac gaacgattcg
    35881 agcagcaatg gacgcagtaa tggattttgg cagaccaaga aaaatttcat tagcagtcct
    35941 ggtcgatcgt gggcatcgag aattgccaat ccgtgcagat tatgttggga agaacattcc
    36001 aacatctcgg gcggaagaga ttttagtaga gatgcaagag cttgatggac aagatcgcat
    36061 catgattttg aaagaggaag attagaggag agagaaacat gtcggagaaa aaaggatttc
    36121 ataatgatga cgtggtgtta gatatccacg atcgcccaac cccaggacat tgggtaggat
    36181 taagtttaca acacttgttc acgatgttcg gagcaaccgt gttagtcccc atcttagtag
    36241 gtatcgatcc aggtattgcg ctagtcagtt caggactagg tacattggtg tacttattta
    36301 ctactaaagg aaagatacct gcgtacttag gaagcagctt cgctttcatt gcagcgatgc
    36361 agcttttgat gaaaacagat ggttatccag cgattgcaca aggagcagtc acaactggat
    36421 tagtctattt gattgttgcg ctgatcatca aaaagatcgg ttcagcatgg ctggataaaa
    36481 tcttgcctcc aatcgtcgtc ggtccagtca tcatggttat cgggttggga cttgcggcaa
    36541 atgcagcaac aaatgctatg tataatcagg gcacgtatga tttcaagtat attgctgtag
    36601 cgctgatcac attaggatta acaattttct tcaacatgtg gctaagaggt tttctcggat
    36661 tgattccgat tttactaggt attattagcg gatacatcgt agccttgctg tttggaatcg
    36721 tggatactaa gccaatcgta gacgctgcct ggtttgctgt tcctaacttt gagattccct
    36781 ttgtacaata tgaaccaaag ctatatcttg gagcaatcac aacaatggca cccatcgctt
    36841 ttgtgacgat gacagagcat atcggccatc ttatggtatt gaataaacta actaaacgta
    36901 atttctttga agaaccgggt cttcataaga cgttgacagg tgatggatta gcacaaatcg
    36961 tggcagcctt tgtcggaggt cctcctgtaa caagttacgg tgaaaacatt ggtgttctgg
    37021 ctatcacacg tgtccatagc gtgtttgtga tcggtggagc tgcagtattt gcagtcattt
    37081 taggattcgt aggaaaatta agcgctttga ttttaagtat ccctggacca gtcatctcag
    37141 gaatcagttt tatcttattt ggagtaattg ccgcaagtgg aatgaagatt ttaatcgaga
    37201 acaaaatcga ttttgataaa aagaaaaatc tgttgattgc ttcagttatc ttagtagtag
    37261 gaattggcgg actcgtcttt gaagtaggca catttacatt gtcggcaatg gcattagcaa
    37321 ctgtacttgg catcatttta aatcttatct taccagaaac ttcacgaagc gaagaaaact
    37381 aaggaggaaa cattatgatc atcaaatcag aacgtatcag cttaaagcat ttattgaccg
    37441 ttgaggcact tactgatcaa gaagttatgg gcttgatccg cagagggcag gaattcaagc
    37501 aaggtgctaa ttggactccg caaaagcgcc agtactttgc tacaaacctc tttttcgaaa
    37561 atagtactcg cacacataaa agcttcgatg tagcggagaa aaaactaggg ctagaagtga
    37621 ttgaatttga agcaagcaca agctctgtcc aaaaagggga aacactatac gatacagtac
    37681 tgacgatgtc agcattaggc gtagacgtag cggttatccg tcatggtgat gagaactatt
    37741 atgacgaact gatacaaagt aaaacaatcc agtgttcgat tatcaatgga ggagacggaa
    37801 gcggacagca tccaacccaa tgcttgcttg atttgatgac catttatgaa gaatttggtc
    37861 attttgaagg tctgaaagtt gccatcgtag gtgatatcac tcactctcgc gtagctaaat
    37921 ccaatatgca gatgttaaaa cgtctaggcg cacaagtatt cttctcaggt cctagagaat
    37981 ggtacgacga tgaattcgaa gtgtacggac attatatgcc attggatgaa ctactagatc
    38041 aagttgatgt catgatgatg cttcgggtgc aacacgaacg ccatgatgga aaagaaagtt
    38101 tctcaaaaga aggctaccat caggaacatg ggttaacagt tgagcgtgcg aagaagttgc
    38161 aaaaacatgc aatcattatg cacccagcac cagttaaccg tgatgtagaa ttagctgatt
    38221 cattagtgga aggattacag tcgcggatcg ttcagcaaat gagcaatgga gtattcgtca
    38281 gaatggcaat cttagaagca gtgctaaatg gaaaagcgta attataggag gatgaaaaaa
    38341 tgaaaacact cattaaaaac ggtcagatca atacacgaaa aaatatgacg acaccagcag
    38401 aaatttggat agaagatggg cgaatcaaag caatcggtac aggattctca gaagccgaat
    38461 ttgatgaagt gtttgatgca aagggacaat tgatcacacc tggtttagtg gacgtccatg
    38521 ttcatttgag agagccagga tttacataca aggagacgat cgaagctggg actcgctcag
    38581 ctgctcgtgg cggtttcact actgtatgcg cgatgccgaa tttaaatcct gtacctgata
    38641 cggcagaaaa gctgagacaa gtatatgaca tcattagaaa agatgcagtt gtgaaggtat
    38701 tgcagtatgc gccaatcaca gaaaatctgc gaagtgagaa attagttgat caagaagcac
    38761 tgattgaaga aggtgctttt gctttcacaa atgacggtgt aggtgtccaa acagctggga
    38821 cgatgtatct ggctatgaaa gaagctgcaa aaaacaataa agccctagta gcccatacag
    38881 aagatgaatc tttattattt ggcggcgtta tgcacgctgg caagaaggca gaagaacttg
    38941 gtcttcccgg gatcttaagc gtaaccgagt cttctcaaat tgctagagat ctgttgctag
    39001 ctgaagcaac tggtgttcat taccatgttt gccatgtttc tactaaagaa agtgtccgtg
    39061 taatcagaga cgcaaaaaaa gcaggaatcc acgtaacagc agaagtttca ccccatcatc
    39121 ttattttgat cgacgaagat attcccgaag atttcggctt ttggaaaatg aacccgccgc
    39181 taagaggacg ggaggacaga gaagctttga tcgaaggctt gcttgacggt acgatcgatt
    39241 gcatcgctac agaccatgcc ccccatggat tagaagaaaa aagccaaagt ttcatgaaat
    39301 caccatttgg tatcgtagga agcgaaacag cgtttcaact gatctatact cattttgtag
    39361 aaactggtcg attcacgttg gaacaagtga tcaattggtt ggcagttaaa ccggctgaga
    39421 tttttggttt gaatgcagga acgctaacgg ttggtgcccc cgctgatgta gcagtttttg
    39481 atattacaca aacttgcacg atcgataaag aagacttttt atcaaaaggg gagaatacac
    39541 cttttatcgg ctggaaagta aaaggcgaaa cacaaatgac ttttgtcaac ggaaaacttg
    39601 tgtggcagaa gggagaataa aagtatggaa cgtttgctta tattagaaga tggaacagtt
    39661 ttcgaaggaa aggcttttgg tgcagatgct agtgtcttcg gagaaatcgt ttttacaaca
    39721 agtatgactg gttatcaaga aactatcact gatcaaagtt ttaacggtca aatcattaca
    39781 tttacctatc ctatggtggg taattatggg gtaaatagag atgattatga atcgatttct
    39841 ccaacatgca aaggagtagt agtaaaagaa catgcacgtg tagcttcaaa ctggcgaaac
    39901 caaatgacgc tagattcatt tttgaaacaa aaaggaattc ctggaatatc aggtatcgat
    39961 acgcgcgccc ttactcgcaa aatccgtgaa gtcggaacga tgaaagctag tatagttgat
    40021 gctggagatt ccttcgaaca tgcatttgat cagctgaaag caaccgttct agcaaccaat
    40081 caagtgcagc aagtctcaac taacaaacct tatccaagtc caggaacagg tcggaaagtc
    40141 attgtcattg acttcggctt gaaacatagt attttacgag aattgagtaa aagaaactgt
    40201 aacctcacag tacttcccta taacacagat gccgagacga ttttagcgct atcaccagac
    40261 ggagtcatgc tgacgaatgg acctggtgat ccaaaagatg tgccagaagc aatcgaaatg
    40321 atcaaaaaaa tccaaggaaa agtaccgatt tttggtattt gtctcggtca ccagttattt
    40381 gctttagcca acggtgcaga tacctataaa atgaaattcg gacatcgagg attaaatcac
    40441 ccggtacgag aagtagcgac cggaagaatt gattttactt ctcaaaatca tggctatgca
    40501 gtcgatgaag ccacgattga tccagaaaaa ctcatcgtaa ctcatgtaga agtaaatgac
    40561 ggaacagtag aaggagtcaa acacagagat tatcccgctt tcagtgtgca gtttcatcca
    40621 gatgctgccc ctggtccgca tgatgcacta catttatttg atgaatttat ggaaatgatg
    40681 gacgcaggaa aggagcagta aacagatgcc gaaacgtaca gatatcaaga aaattatggt
    40741 gattggatct ggtccgatca tcattggtca agccgcagaa tttgactacg caggaacaca
    40801 agcctgcctt gccttaaaag aagaaggata tgaagtggtt ttagtaaatt ctaatcctgc
    40861 gacgatcatg acggataaag aagtggcaga tcaagtatat atcgaaccga tcacacttga
    40921 atttgtatca aggattcttc gaaaagagcg tccagatgct ctccttccaa ctttaggcgg
    40981 acagacaggc ctcaatatgg caatggagct ggcagcatca ggtattttag aagaattgaa
    41041 catagaactt ctaggaacaa agctttctgc gatcgatcaa gcagaagatc gtgatctatt
    41101 caaacagttg atgaaagaat tgaatcagcc aatccccgag tctgaaatcg tcaatacagt
    41161 agaagaagct gtagattttg caaataaaat cggctatcct gtcatcgttc gtccagcctt
    41221 tactttaggc ggaactggtg gaggtatgtg tgaaaatgaa gaagaattac gtatcgtatc
    41281 agaaaatgga ttaagtcttt cccccgctac ccaatgtttg attgaacgaa gtattgcagg
    41341 ttttaaagaa attgaatatg aagtgatgag agattcggct gataatgcaa tcgttgtctg
    41401 caatatggaa aattttgacc cggtgggtat ccatacaggt gattctatcg tatttgcccc
    41461 tagtcaaaca ttgtctgacc atgaatatca aatgcttcgt gatgcttctc tttcgattat
    41521 tcgagcactt aagatcgagg gaggctgtaa tgtccaactc gctcttgatc cacatagttt
    41581 taattattat gtgattgaag tcaatccgcg tgtttctcgt tcatctgcgt tagcaagtaa
    41641 ggcgactggc tatccgatcg ctaagctagc tgctaaaata gcgcttggat taacattaga
    41701 cgaaatgaaa aatcctgtta caggaacgac ttttgcagaa tttgaacctg cattagatta
    41761 tgttgtagct aaaattcctc gctggccgtt tgataagttt gaaaacggag aacggctttt
    41821 aggcacgcag atgaaagcaa ctggtgaagt gatggctatc ggtcggaata tcgaagagtc
    41881 tttattgaaa gctgtgcgtt ctttagaaat cggtacacac catatcgaac ttcctgagtt
    41941 ggcagacatc acggacgatg acctaatcca aaaagtggtt cgagcacaag atgatcgcct
    42001 gttttatgta gctgaagcta ttagaagagg gtacaccata gaagaattag cggatttgac
    42061 aaaaatcgat ttattctttt tagataaact gttgcatatc gtagaaatcg aacagcagtt
    42121 gaaacagcag ccgttggatg acaagatatt gaaaacagcg aaacaaaacg gttttacaga
    42181 caaaaaagtg gcggagctgt gggaaataaa cgaagaagcc gttcgccaga tgagaaaaga
    42241 aaatgatttg attcctgtat ataagatggt tgacacttgt gcagcggaat tcgaatcaaa
    42301 aacaccttat ttttatagtt cctatgaata tgaaaatgaa agttcacgat cagaaaagcc
    42361 ctcaattcta gtactgggat ctggtcctat ccgtatcgga caaggggttg aatttgacta
    42421 tgcgactgtg cattctgtca aagcaatcca gcaggcagga tacgaagcaa tcatcatgaa
    42481 cagcaatcct gaaacagttt cgactgactt ttctatttcg gataaattat attttgagcc
    42541 attgaccttc gaagatgtga tgaatgtgat cgagctagaa cagccgatag gagtaatcgt
    42601 tcaatttggt ggtcagacag caatcaactt agccgaacct ttgactgctg ctggtgtaaa
    42661 aatcttaggg acaacgatcg aagacttgga tcgtgcggaa aatcgtgatt tattcgagca
    42721 agcgctgaaa gagttggata ttcctcaacc tttaggggat actgctacaa gtaaagaaga
    42781 agccgtggtt atcgcttcga gaattggtta tccagttctt gttcgtccaa gctatgtatt
    42841 aggcggacgt gcgatggaaa tcgttgaaaa ccagcgagat ttagaagatt acatggaaca
    42901 tgctgtgaaa gcatctccag aacatccagt actagtggac cgttacttgc ttggtggtga
    42961 atgcgaagtg gatgcgattt gtgacggtga aacagtactc atcccaggga tcatggagca
    43021 tattgagcgt gctggtgtcc attcagggga ttcaatggct gtgtatccac ctcaaacatt
    43081 atctgaatcg atcaagaaaa cgatcgaaga ttacacgatc cgcttagcat taggtttgaa
    43141 ttgtgtcggg atgatgaata tccagtttgt catccatgaa aatgaggttt atgtgatcga
    43201 agtcaatcct cgagcaagtc ggactgttcc attcttaagt aaggtgacag gaattccaat
    43261 ggcacaaatt gcgacgaaag ctattttggg agagaaacta aagacacttg gttatgaaaa
    43321 cggactttat ccagaaacaa aagaagttca tgttaaagca cctgtctttt cttttacgaa
    43381 attgcagaaa gttgatactt acttagggcc tgaaatgaaa tcgactggag aagtaatggg
    43441 atctgacaga caattagaca aagctttgta caaggcattc gaagcttctg gattacactt
    43501 gcctgaatat ggagccgtat tatttacgat tgcggacgaa acaaaagaag aagcactaga
    43561 attagctaaa cgttttacag aaattggcta tagtctgata ggaacgaaac atacagctgc
    43621 ttatttcgaa aaaaatggtc tggtcgttga aacagtagcg aaaatttctg aggaagcagc
    43681 agaaaaaaat gtagtcgact taataagaga tggtaaaaca caagtggttg tcaatacgat
    43741 tgataaagat cggggaaatg cttctaaaga cggtttcatc atccgaagag aagcagttga
    43801 acatggtatt ccattgttta cttctttaga cacagcagat gcgatcgttc gagtgatgga
    43861 atcccgtgct ttttcaacta accctattta acggcgagca catgttaaga caaaaagacg
    43921 aaaaaccgtt gcaggagggg acagatgaaa caagaaatga tggaaatcgt tcagcaaaaa
    43981 cagctggcac caaagatttt tgaaatgaca ttgaaaggtg atctagtaaa agaaatgcag
    44041 caaccaggac agttcttgca tattctcgtg ccgcgtgcag acttgctatt acgccgaccg
    44101 attagcttga atcatatcga ccacgaaaca aatacttgcc gtatcattta tcgggtggaa
    44161 ggtgagggga ctagagtctt ctctactctt tctgccggag accatttaga tgtcatgggt
    44221 cctttaggca atggttttga tttgtccaat cttcatacag gagacgaagt atttataatc
    44281 ggtggaggaa tcggtgtccc tcctctatat gagttatcaa aacagttagt cgaaaaagga
    44341 attaagccaa cgcatttttt aggttttgcc acacatgaag tcgtttatta tgaaaaagaa
    44401 tttaatcgtc taggagaaac aagaatcgct actgacgatg gaacatacgg tatgcacgga
    44461 aatgtcggta atttattgtt aggaacgaag acggaaccta cagctgtttt tgcatgtggt
    44521 tcaaacgggt tattgaagac agtggaacag ctgttttctt cgcatcaaaa tgtccagtta
    44581 tcattagaat cccgcatggc atgtgggata ggggcttgct atgcttgcgt ttgtcatacg
    44641 ccggaagatg aaacaggaac aaaaagtgtg aaagtttgtg acgaaggacc gatttttaaa
    44701 ataggagagg taattatatg aatgagaatc ctttagcggt caaacttcct ggcctagaat
    44761 taaaaaatcc tatcatgccg gcaagcggct gtttcggttt tggcaaagaa tacggaaaat
    44821 actatgattt gaatcagctt ggatcgatca tggtcaaggc aacgactcca aatgcccgct
    44881 ttggcaatcc cacgccaaga gtggcggaaa caccatctgg catgttgaat gcaattggtt
    44941 tgcaaaatcc tggtctagac gttgttatgc ataaacttct tccagaatta gaggagtaca
    45001 atgagttacc catcatcgca aatgttgctg gtgcttgtga agaagactat gtagaagttt
    45061 gtagcaaaat tggcgaagca ccaaatgtga aagcaatcga gctgaacatt tcttgcccaa
    45121 atgtcaaaca tggcggaatt gcttttggaa cagattctga tgttgctttt caattaacac
    45181 aagcagtaaa gaaagtttct tctgttcctg tctatgtcaa attgtcccca aatgtaacag
    45241 acatcgttcc aatcgctcag gcaatcgaag ctggaggggc agatgggttt acgatgatca
    45301 atactcttct tggtatgcgg attgacctta agacaagaaa accgatttta gccaatcaaa
    45361 caggtggact ctccggacca gcaatcaagc ctgtcgctat tcgtttgatt caccaagtag
    45421 caagtatatc cagccttcca atcattggga tgggcggcgt gcagacagtg gatgatgttc
    45481 ttgagatgtt tatggctgga gcaagtgctg tagctatagg gaccgcgaat ttcaccgatc
    45541 cgtatatctg tcctaaacta attaaagagc tccctgtgcg aatgagcgaa ctaggcatcg
    45601 aatcgctgga aagattaatc aaagaagtga gagaggaacg tgaacgatga atcaactaga
    45661 ccaacgacca attattgcat tagatttttc aactaggcaa gaggtagaag actttcttcg
    45721 atttttcccg aaagaagaaa aattgtttgt gaaaatcgga atggaattgt tctaccaaga
    45781 aggacctgaa atcgtacgtt atctaaaaga ggctggtcat aatgtatttt tagatctgaa
    45841 acttcacgat attccgaata cggtcgaaaa agcaatgcgg ggattggcaa agcttggtgt
    45901 tgatctcacc tgtgttcatg ccgctggcgg tattcgtatg atggaggcgg caatgcgagg
    45961 attagaagag gggactccag aaggtggaaa acgtccgcta cttctagcta tcactcagct
    46021 tacttctaca agtgaagaag aaatgcatgc cgatcaacta atcgaagttt ctttagaaaa
    46081 aagtgtgatc cattatgcta gctgtgccaa aaaagcagga ttagatggtg tggtttcttc
    46141 tgcttgggaa gtagaagcga tcaaagaaat ggcaggagac gaatttgttt gcttaactcc
    46201 gggtataaga ccagaaggaa cagtcgcagg agatcagaca agagtagtca caccttctca
    46261 ggcaaaaaag atcggctcaa cttttatcgt tataggtcga ccaatcactc agtcaactaa
    46321 tccttataaa gcatatcaaa cgattcaaac agaatggagc taacctaaaa tgaatgttga
    46381 acaaagtatc gcaaaagact tattagaaat tgaagcagta tttttaaatc caagtaatcc
    46441 ttttacatgg gcaagtggaa tcaaaagccc aatttactgt gataaccgaa tcacgatgag
    46501 ctatccaaaa gtccgaaaag agatcgcaaa aggattagca agcaaaatca aagaagctta
    46561 ccctgaagta caagtgattg ctggaactgc aacagcagga atccctcatg ccgcatgggt
    46621 agcggaaata ctggatttgc caatggtcta tattcgaagt aaggcgaaag atcatgggaa
    46681 aggtaaccaa atcgaaggac gtatatttga aggtcagaag atggttgtga tcgaggattt
    46741 gatttctaca ggcggaagtg tcttggaagc agctgaagca gcaaaaagag aaggtgcgga
    46801 tatccttggt gttgcggcta tctttacgta tgagttgcca aaaggaaaag caaatttcga
    46861 aaaagccgaa atccctctta tgacgttgac caattattct gtattgattg aagcagcttt
    46921 agaagatcgt tatatcgatg agcaagaatt aactctgcta aaagaatgga aaaaagatcc
    46981 tgaaaattgg cagatttaag cgcgcttgat gaagatagag aaatccgatt tgtgtctcca
    47041 gaatcatcaa ttggaatagc aaaaatccaa aaactgattg cgagaagcat cttttcatca
    47101 ggtatgaaaa gaaacttcta tcgtgatcag tttttgattt ttttaaaatt catttttcta
    47161 agactggtta gcagaaagaa gagaataatc tcttctcttt tttctattat atatagattt
    47221 tctctatttt ttggtaaggg agctgtttca aaaatggtaa agagcggaaa tgttgcgaat
    47281 atcagttatt taatgatatg atattcggaa aaagaaatct caaagggagg taacttttat
    47341 ggggttgaat gaatttattt taggattgaa caatttagag acgatcacaa gggcacctgg
    47401 attttttaaa tatacagagc atacagttgc agcacattcg tatcgtgtag catctattgc
    47461 gcaagttcta ggagacattg aagaagcgaa tggacaaccg atcgattgga aactgctcta
    47521 tgaaaaatca ttgaatcatg actacacaga gcgttttatt ggtgatatca aaacgccggt
    47581 gaaatacgca agcaaagagt taagagggat gctgcaaaca gttgaagaaa agatgacgga
    47641 cgaattcatc aaccaagaga ttccagctga gttccaagaa gtttatcgcc gtcggttgtt
    47701 cgaaggaaaa gatgaaaccg tagaaggaga actattagcc atttcagata aggttgacct
    47761 tctttatgaa tcttttgatg aaatcatcaa aaataacccg gaaaaagttt ataaggagat
    47821 gttcattgag gcagtgacta cgattaaaag ctttgaacat cggccttctg ttcagtattt
    47881 ctttaaagag atatttccgg aactattgaa ccaggaattt tatggaaaag aggcgttttt
    47941 agaaaccgtc tcaacgattg taaagaaaga agaaaaataa aaatgatatg agatgcaggg
    48001 ggaagtatag ttgaaaaaga atatggatgt cgaatggggc tattctggag acaaaggtcc
    48061 ggaaaattgg gcgagtttat gtgattggtt tgcgagaggt gcggaatttc cattgcagtc
    48121 gcctattcat ttgaccaagg gggaagaaac caaaatagaa ggagacacgc tttcctttca
    48181 ttatcaaaag caacggttta ctgacaagga attcaaaaac acgattcatt tagtaccttt
    48241 tgaccaactc agttatgtag agttcaagaa agaacgctat tatttgacag atattcattt
    48301 ccacttgcct tctgaacata tcatcaacgg aaaacaggaa gatattgaat ttcattttgt
    48361 tcatatgaac agcaaaaaag agaatctagt tgtgggtgtc atgtaccagc taatggtaca
    48421 ggaaggttgg ctgtataatc aagaaaatgg ggaaagttgg aacttagaaa aacatgagca
    48481 ttgggtaaat ccggatgtgt tctttccgga gcaaaaaagc catttccatt atattggctc
    48541 attgacaact ccgcctacca gcgggccaat ccaatggttt gtaatggatc atgtaggaaa
    48601 actgaaccaa gagtttcttc tccccttcga tggtcagtat gctcgaccga acaaccgacc
    48661 aatccagccc ttgaatggaa gagaaattta ttatttcgag gagtttgagc aatgaatatt
    48721 cagcagatga aatacgtggt cgctgtagca aacaatggta gtttcagaga agcggcaaag
    48781 aaaatgtttg tctcccagcc aagtctttca gctggtatca aagaattaga aaccgagtta
    48841 gggatcacgc tgtttactcg aacgaatcga ggggcatatt taacagaaga agggcaagac
    48901 ttcttaaatc gtgccgagaa aatattggtc cagcttgata cattagaaac tcactatcta
    48961 acgagtgaaa agagagacaa tttttcgatc gctgcccagc attatgattt cttaggtcct
    49021 ttgaccgcac agctactcga ggaattcaaa gacgagatca aacaatttcg gatcatggag
    49081 acgacaacag cgagagtgat cgaagaagtc aaagagcagc acagtgagat cggcattatt
    49141 tatatgaatg agcataatca agctggtatc agaagatatt tacaacaagg agagctaagt
    49201 ggccgcagca ttggaaaatt caaaacgcat atttttttaa ggcaaggaca tccattagct
    49261 gaacacgcag agatcaccaa agaagaattg ttatcttatc ctcaagttcg ttttacacag
    49321 gatggaaata atttcccgta tttttatgaa gaccttatcg agatccctga tcaagaaaca
    49381 gtgatttata cgagtgatcg aggtactttg atgaatatcg ttcttgaaac tgatgcttac
    49441 gcttcaggat ctggtattgt gattggaggg attcgcgaac acttgcggtt aatccctttg
    49501 gcagaaggcg aactaaatga attttatatc atttattcgg cgaaacgtcc gctcagtgaa
    49561 atcgctcaaa gatttatcaa agagcttact cggttactgg accagcagag ctaagaaaag
    49621 cagatgagaa cgctgtttat tgaacaccgt tgatcaaaaa agaggggttg tgacagaatt
    49681 ttgtcacaac tcctcttttt gtagcaaaca atttataact aattgctgtt gtgggaaagt
    49741 acgcaaatat gattctagaa acactcattg attacctgtt ttgtttcata gctgtaattt
    49801 tttcttcttc tggtgtcacg ataatcgtct tttggttttc ataaataaca taaccaggct
    49861 tggcgccatt tggttttcgg atatgcttta cctgtacaag atcaaccggc acttgggcag
    49921 agtatcggta ttttgaaaaa taggcagcta actcggcagc ttctgtaatt gtttcatctg
    49981 agggcttgtc acttttaatg atgacgtgcg aaccgggtat attttttgca tgaagccaat
    50041 agtcggtttt tttagctgtc ttcattgtca gctggtcatt ttgaagattg tttttaccaa
    50101 caagaatgag cgttccgtca gaagaaaagt attgatcagg ctgagatggt ttcttacgtt
    50161 tttgtttttt taagttcttc tttttcaggt atccttctga agtcaattct tctttaattg
    50221 cttcgatatc cattgggccg gcaatttcca gttgagataa gacagattca agatattgga
    50281 tttcatcttt ggcttcttgg atttgttcgc caatcagctt aacagcgttc ttcagctttt
    50341 ggtatcgatg gaaatatttc tgtgcatttt gatttggtgt caatgccgga tctagtgcta
    50401 ttttgattgg ccgatcttct tcataataat taggtaaaac aacttctttt gcgccgcgtg
    50461 gtacttgtgt cagaaaagta gtaagtagtt cgccatttct acggtaattc tcagcgtttt
    50521 cggattcttt gagtgtttgt tcacgttttt tcaatttatt tttatttcgt tttagttcat
    50581 tttcgatttt tcgaatcagt tctccgcctt gttgttttgc ccgatctttc tctgcttttt
    50641 cgtgataata gctatctaat aattgactga gtgttggata agctgttaca gcagatgcct
    50701 gttcggacaa tacctgataa gcaatcggtg tgaaaaaatc tttattttcc gtttcgtaaa
    50761 aagtaggaat aggctgatgg ctgatggctg agaaaaattc gtcccataca accatctttt
    50821 cattaggacg ttccagtaat cttttggtca gctcttgagc gatatcgaaa ccgattccct
    50881 gaaactgacg ttggattgct tttggatcta gttcagtttg ggaaagccgc tgaaagattt
    50941 tttctttctc ggagctaaat gggttcaaga cctcttgttt tggcggagca acatattcta
    51001 caccaggaag caaagaacga taagtgtttt gagagcttcc aatgtgtttg atcgcatcca
    51061 gtatttttcc agtttctcga ttaactaaga cgatcgtact atgacgtccc attaattcaa
    51121 cgatcaatat gatattttgt agatcaccca actcgtttcg tttagcaaag tggaaatgga
    51181 tcactcgatc attttcgatt tgttcgatgt cttctaaaat agcgccatcc aaatattttc
    51241 gaagcatcat cacgaagtta ggcggattat caggattctg ataatcgatt tgggtaatct
    51301 gtacacgagc ataacttggg tgcgcagata ataataatcg atggtttttg ccgcgtgaac
    51361 gaatcaccag cacgatttca ttttcataag gctgatggat tttcgagatc cggccagata
    51421 gtaacgtttc acgcaattcg ttgaccatcg cgtgggtaaa tacaccatca aaggacatgg
    51481 ttcattcctc atttcttttc ataagtatat tcattataac gaaaaaaaga agaaaaacca
    51541 atttggccga atagtaaagc aaaagtctag aaaaatcttg gactaattac ataaaaaaca
    51601 gtgtttctat cgttgaaatc caaattttta ggtataataa aaaataggag aaaaagtaga
    51661 aaagaaggtg tttgttattt gggaagtagt taaatcgaga gtacaagaaa tgaatgaaca
    51721 tttctcagtg tcattcgcag aaaatccaag taagtatttt cgacgtcttg tttttctgct
    51781 catcttatca ttgctgttaa cagttgcaat gtttttattg ccggaaaaaa tccgagaaga
    51841 gcaagtaaat agtctcgttt attcgtccat accaaccagc aaattgaaac cttttgatta
    51901 cagcaaagct gatcagaaaa tcaaacaaag ccgggcgata tcggtgatgt tcagcaaacc
    51961 gaacgggaaa acctatcagg acatgcttga tgtttttaat gatcctgagc ttatggaaga
    52021 attgaatcga ccgatctttt attatccgat cgtttatgat gtacatgaac tggaacaaaa
    52081 atataacata cgaacggatg aagtgacatt tattttcttt gatggaggaa aagaagcaaa
    52141 tcggataact gcgggtaagg gaggaataac tgattttgat aaggagttga tccctgaact
    52201 gaatcgactt ccgttagcca atatcaaaca attagaagaa gaattggata gaacgggagt
    52261 aacttcccaa aattccgaga ttgctaattg agacattggc gcgatgaaac ggtgggtcta
    52321 tatagcgcta tttttaatta tcagaacaag tgatgtttga tcttcaaaat aacaaataaa
    52381 aaattaaaaa atatagttga cgaaattcaa aaattcgatt agacttaaat caattcttaa
    52441 ggaaagggtg acctgtaatg aacttatcaa aacgtatttc agcagaaaac aaaaaaaatt
    52501 ggcgcagctg gcgtagataa gttgtattaa tggtgagact ttcccataga tacaactttt
    52561 tagagtgcat ttctaaagct tgtatctatg ctagacatga acattgactg ccgcatagat
    52621 tagaatctat gcggtttttt gtgtaaagac aatgaccgct ttggccattg tctttttttg
    52681 tagactggat acttgcctga ttataataaa taaaaagatt gactttgcag gaggaaaaaa
    52741 atgaaaaaca aacgattaat aacagttgta gtaattattt tagtttattt agcaggtgca
    52801 tttatttatg gaaaagcctc aggcgaaaaa gaaagtactt cgacgaacca gacaaaaaaa
    52861 acaacagttg ttggggtatt gcaatacgtg agccatccgg cattagatga gatttatcga
    52921 ggaatcaaag atggtctgaa agaagaagga ttaaaagaag gagaaaatct tgagatcaaa
    52981 tttcaaaatg gacaagccga tcagagcaag ctagccacaa tgagtcaaca gctagtacaa
    53041 tctgatccag atgccttgat tggaatcgca acacctgccg ctcaatcatt agcaaacacg
    53101 acttcatcga tcccagttgt gttaggtgct gtaacggatc ctgtgggggc tggattagtc
    53161 gcttctttag agaaacctgg tggtaatgta acaggtgttt ctgatcagcc gcctgttact
    53221 tcacaaatca agcttgcttc tgatttgttg ccaaatgcaa aaaaagtcgg aatcttgtat
    53281 gcttcttcag aggataattc aaaataccaa gtagcacaag cagaagaagc tgcaaaaaaa
    53341 gaagggttag aatcagtaaa atatgcggtg ccttccacta atgagattgc acaaacggtt
    53401 caagtgatga gccgacaagt cgattttatc tatgttccat tagataatac cattgccaat
    53461 gcgatgcaaa cagtggtaaa agaagcaaac aaagcaaata tccccgtcat tccatctgtg
    53521 gatacaatgg tggaacaagg tggactagca acaatcggga tcaatcaata tcaattaggg
    53581 cttcaaagcg gtaagatggc ggcagaactt gcgagtggaa aagaaaaacc ggaaacgacg
    53641 cctgtttata catttgatca aggggataca gtgatcaatc aatctcaagc tgatcgctta
    53701 ggaatcattg ttccccaatc gatgaaggaa aaagccaaaa tcattacaga tgactcgcag
    53761 caagaaacat ctaaggagga tgacaaatga tcgtatcagc tatttcacaa ggcatgcttt
    53821 gggcaatatt aggattaggg attttcatga cttatcggat cttagacttt cctgatatga
    53881 cgacagaagg gtccttccca ttaggtgctg ctgtctgtgt gacagctatt actcatgggg
    53941 tagcgccgat tgtagctaca ttattaggcg taggtgctgg catgatagca ggactcgtta
    54001 cggggttact ttatacaaaa ggaaagatac cggttatttt agcagggatt ttagtgatgt
    54061 caggattgaa ctcagttatt ttgtttgtga tgcgaacacc aaatctttct ttattgaatc
    54121 atccgattct acaagacagc ttccatcgct ttgggttacc tgattacttt gacacagtcc
    54181 ttcttggctt catctctttg ggcatcttga ttgctgtact gctattcttc ttcaatacag
    54241 atttgggtca aggctatatt gcgacaggag acaacgaaac gatggctcgg tcgttaggga
    54301 taaaaaccga tcgtatgaaa attttaggtt taactttgtc gaacggtgtc attgcattat
    54361 ccggtgcgct gattgcccag aacgacggat atgcagatgt aaataaaggg attggcgtaa
    54421 tcgtcatcgg tcttgcttcc atcatcatcg gtgaagtgat cttccaagaa ttgacgctag
    54481 cagaaagatt gattgctatt gttgtcggca gtatcattta tcagctattg attttagtag
    54541 taatcaaact agggtttgac acgacttatc tgaagttgtt ctccgctatc atcttagcta
    54601 tttgtctgat gatcccgcaa ttgaagaaag cactgaactt aaaaacgggt tttgagaagg
    54661 aggcatagta atgactgata tattgacaat caaaaatggc agaaaagtcg taaacaatgg
    54721 aatgaatgaa gagaaagtac tattggatga aattaacctt acaatcagag aaggggactt
    54781 catcactgtc cttggcggga atggtgctgg aaaaagcaca ctgttcaata cgatcgctgg
    54841 tacgcttcaa ctcagtcaag gatcgatctc ttttaaagat cagctgatca caaaagattc
    54901 agaagaaaaa agagcacgat tcctttctcg agttttccaa gaccccaaga tgggaacggc
    54961 tcctcggatg acagtagcag aaaatttgct acttgcacaa aaaagaggtc aaaaacggaa
    55021 attccgttta cgtaacttga aaaatcaaaa agaagatttt ttcagactat gtcaagaagt
    55081 cggtaatggc ctagagcaac acttggatac tccagcgggt gaattatctg gtggtcaacg
    55141 ccaagcatta agcttgctga tggcgacgat cacagctcct gagttactat tattagatga
    55201 acatactgca gctttagatc ctaaaacagc taaagcatta atgcgattaa caaatcagcg
    55261 gatcaatgaa caaaaattga cttgtctcat gatcacgcat cgaatggaag acgccttgaa
    55321 atacggaaat cgtctgatcg tactccaaaa agggaaaatc gttcaagata tttctgaaaa
    55381 agaaaagcaa catttgacaa tgggcgacct tttgcagttc tttgaagaag tagtggattg
    55441 atttcgacag aaaaattcct ttcagtagaa ggacttgaaa actcattgac atcttccttt
    55501 gattcatcct atacttaaaa caataaacaa ttaaacatat ttgggtgttt tgtaggatca
    55561 cgtagtcaat gattttaaca attaaataga atattctttg ctctgacaag taaacgatga
    55621 gaaaagaatt tgctactttg ccacctagac gtttcgtact ttttcgtatc aaacgctaag
    55681 tggctttttt tattgaagta agaacaaagg aggaataaga tgatttctgg acaaaccaaa
    55741 ttagctgggc tctttgctga tccggcttct cacagtttat ccccattgat gcacaatact
    55801 gcttttgaag caaacaacat cgatgcggtg tatttagctt tccaagtaaa tccaatgaat
    55861 ttgaagcaag cagtcgaaag tattcgaact tttgatatgt taggtgtaaa tctttcgatg
    55921 ccgaataaaa cagcggttat tccttatctg gatgaggtaa gccaggaagc gcaattgatc
    55981 ggagcagtga atacgatcgt gcacgaaaag ggtcgtttga ttggctataa tactgatggt
    56041 gcgggcttca tgcaatccgt gcaagaagct gggatttcga tcaaaaagaa aaaaatgact
    56101 ctactgggag ctggaggtgc agcaaaggca gtcactgttc aagcagcgtt agacggcgct
    56161 gaggaaatcg tagtttataa acgaaacaac caaacattcg ctcaagtaaa agaaacattc
    56221 gaacaactca gctatcgaac ttcttgtaag ataaaagttc gtgactttgc cgatacgcat
    56281 caattaagaa aagacttgaa agaaagctgt cttctagtca atgcaacaga tatcgggatg
    56341 ggaaagaaaa tcaatcagtc accgctctta gatataagca tgatgcatga gaatctagcg
    56401 gtttttgatt tgatttatgc acctagagaa acacgtttat taaaagaagc aaaaaaagta
    56461 ggagcaaaag gatacaatgg acttggcatg ttgatctacc aaggagcaat cgcgtttgaa
    56521 ttatggacaa aggaaaagat gccgatccat gtgattgaaa agctgtttga ttaaaaaagg
    56581 ataatagata aagatctttt attctcgcat aaacggtctc aagaaaagta atcctttatg
    56641 tatcgaagca tttatttcgt tattttttat taaattatca aaaaatgata ggcttttgtc
    56701 gattggttat cgtatccttt atttatcagt aagaaacgag gaggaaccac aatgagtcgg
    56761 atggatcgct ataaggacat ccataagaag gcgaaacctc tgaagcggga tacggggagt
    56821 atttttgcta gaagagaacg aaaacgaacg cgtatggaaa atgaggaaga tgctacccgt
    56881 atttatgaaa gagagcagca ttcatttgaa catttgaacc aatacgagca acagatatac
    56941 agagatgcac caagagcaga agaacaacaa aaaaataaaa aatttttcaa tcggcaaaag
    57001 aagaacaaac cgttaaaacc tcgaagaaag cgatcgtgga aaaaaatcat tctatcgatt
    57061 ttgcttgttt tgatccttta ttcaggtatc tcatttttta ttggtaaata tgtagctgaa
    57121 catgacacaa gcttagaggc agcgacttca gaaacctttc atgggcaaaa agcgacgaat
    57181 ggtgcgcata atattttgat ccttggaagt gatacacgcg gagaagatgc cgggcgagcc
    57241 gatacgatca tggtcttaca gttggatggt ccttcccata agccgaaact gatttctttt
    57301 atgcgtgaca gcttcgttac gatcccaggg gtaggacaaa ataagatcaa ttcagcttat
    57361 gcatacggag gagccgatct agtgcgtcaa actttagtag aaaattttgg aatcgattgt
    57421 caatactatg cgaaagtcga tttcaaatcg tttgaaaaag tgatcgatgc cttattcatg
    57481 aacggagtga agatcgatgc agaaaaagat ctgaatctgg atggtgtaga tattaaaaaa
    57541 gggggccaga agatggatgg acatgttctt ttgcagtacg cacgtttccg aatggatgaa
    57601 caaggagact ttggccgtgt cagacgccaa cagcaagtaa tgaacgctat tttcagccaa
    57661 ttgaagaatc cattgaatct gatccgtgca ccttatgcag ctggtaaagc tttaggatat
    57721 acatccacag atgtcactgc ttggttcttg acgaaaaacc tcttttcgat tgcacgagga
    57781 gctggtggca ttgatcgaat aagtgtgcca gtagacggtt cgtggaatta tgggcaaagt
    57841 gattatgctg gcagtattct tgaaattgat aatcaaatga atcaatctgc tattacagat
    57901 tttttgaata aatgatcata aaaaagatca agaagaagct gcgcaaggct tttgtcatga
    57961 atcaatcaaa cgattcactc gtaaaaaacg ctttcttatg gtagatttaa ccaagagagg
    58021 agctgtttac attggatatc tatctgaact tcaaaaatga gtcgcgtgaa gccatcgctt
    58081 tttatgaaaa agtttttcag actgaagcat caggtatcac cacatacggt gaaatgcctg
    58141 gaatagaaca aatgaacttg ccagaagaag caaaaaatct aatcacgaat gcacggctga
    58201 acatttatga tacattagtt atgtttgcag atacgccaga aggaattggt cctgaattag
    58261 ttgtgggaaa taatgtttct ttagtcatcc agacaagaaa tgaagaagaa acgaagcgcc
    58321 tatttgaaag cttagctgag ggtggtaaga ttgagatgcc actggatgct gttccgtggg
    58381 ctcagttgta tgggatggta actgatcgat ttggcatcaa ctggcagatt aaccaagagt
    58441 gacagctaaa gatgaatatt ttctggaaac atcaagcagc aaacggatca tcgtttgttt
    58501 gcttgatgtt tttgtgtcta tttcgactat acggtatctt ttttttattg ccagatgcga
    58561 aaatatgttc cataatagag aagtccgcaa aaaattaagt aacggaggtc agaagatgaa
    58621 gacggtgata ctagctgaaa aaccttcaca agcaaaagcc tatgccgaaa ccttccaaca
    58681 gcaaaagcgg catgaagggt attatgaaat cagcgatcca ttgtttgctg gtgaagtaac
    58741 catcacttat ggttttggac atttggtaga tatggttgct ccaggagctt atgaagagcg
    58801 ttgggcaaaa tggtctttag aaaatttgcc tattttccca gaaaccttcc gttacgaagt
    58861 tccaatggac aaacgtgcac aattttcgat cgtaaaacga gaattgcagt cagccgatac
    58921 catcattatt gcaacagatg gtgatcgaga aggtgaagcc atcgcgtggt cgattattcg
    58981 acaagcaaac gcattttcta aggaaaagaa ctatttacgt ttatggatca attctcttga
    59041 aaaagaagca atctatgaag gttttaagaa tctccaacct ggaaagaact attttccaaa
    59101 atataaagaa gcgcaagcaa ggcagaacgc tgattggctg attggaatga atggaagtcc
    59161 attatatagc ttgctacttc aacgaaaagg gattgatggc agtttttctc ttggtcgtgt
    59221 acaaacaccg acactctata tgatttatca gctgcaagaa gaaatcaaac acttcaaaaa
    59281 agaaacgtac tttgaaggag aaggtttaat tacgacaaac aaagggcagt tttctggaaa
    59341 aatcgtacca aaaaaagcat ttaaaaccca agaagagtta acgaaggaaa tagaaaaact
    59401 tggagcgcat ttaggtaagc aaaacggacg gattcttgaa gttacgaaaa aggaaaagag
    59461 gttgcatagt ccacgtttat tttcgctatc tagtttgcag acaaagatga atcagctaat
    59521 gaaagcaagt gccaaagcta cacttgatgc tgctcaagga ttgtacgaaa gcaagtttct
    59581 aagctatcca agaacggatt ccttttacat tacagaaaat gagcatcagt atctggttaa
    59641 acatctgcaa aattataaaa aatttttagg aatagaagaa gtacagacaa ctgagatcaa
    59701 agcaaagaaa cgatatgtcg atgcgaaaaa agttcaagaa catcatgcaa ttattccgac
    59761 aaagacgatt ccgactcctg cacgctttgc gaagctttcc aaattacagc aagcaatcta
    59821 tttgcaagtt ttgcgcacta ctgtggctat gtttgctgca gattatatct acgaagagac
    59881 gaccgtaatg acgggcgtac agcaattaaa gctaaaaagc atcggaaaga tcccattaca
    59941 gcaaggttgg caggaaatct tacgcatcaa gtcaaaaaag aaagaagctc agactcttcc
    60001 tcctatcgta gaaaatgaag aagcagaagt agaactgaaa agtatggaga aagaaacaca
    60061 acctccaaaa ccctataccg aaggaacgtt gatcacagca atgaaaactg cgggaaaaac
    60121 gctggataat gatgaagcgc aagaaattct caaagaagta gaaggaatag ggacagaagc
    60181 tacacgagcc aatatcattg aaaatcttaa gcagaagcat tacatcgaag tcaataaaaa
    60241 cgaaataact gttacgccaa aaggaatcac tctttgtaag gcagtagcca atgaaccatt
    60301 actgacgagc gcagaaatga ctgcgcgctg ggaagggtac ttgagaaaaa ttggtaaaca
    60361 agaggggaca ccatctgttt ttttagagaa tatcaaaaaa ttcatcctac atttattggc
    60421 agaagttcct aatcaaatcg acaaggtaga cttttcagat gagattagcg ggacacgtca
    60481 gataaaagcg atggagaaga aaaacgatca attaggaaga tgtccaaaat gtaaaaaggg
    60541 aatagtcatg ctttatccta aaatcgctac atgcttgaat ccggaatgcg acttcaaatt
    60601 gtggccaaca gtagctaaaa agaagctgac taaaacgaat ctcagagatt tgctttcaaa
    60661 aggaaagaca agtaaagttg tcaaaggttt tactggtaaa aaagggaaat tcgatgcagt
    60721 tttagtatta aaagaagata tgacaatcgg tttttctttt ccatggatcg aaaacagtgg
    60781 aacaaaagca gttgatggaa acaaagaaac atcaagaaaa aataatgaaa acgaagtaga
    60841 gtaaatgaaa acaatgaaat agcggaatat ttattccgaa aagtgagaat ataaatacca
    60901 ataaaactaa aaaatatcag tgaatcaagc aaaaacgttg gggtaggctg attttatata
    60961 gatagcaagg agttttttta tttgaaaaaa gtgcattcat ttttaaatta tcttatggga
    61021 gcaatcacga ttgtggctgt gtaccaagca tttctaaagt atcctgatta cgggacgaag
    61081 ttgttgtcat tgacgcacaa tcaaacagca tattcaccaa cgttgatttt atcgactttg
    61141 actgcaggag ctaaaagcgc tacttatttt tttcataaaa cgacaagcat gctaaagcga
    61201 aagaaacagc gaaaacaatt gttggtggtg gtagcggcta tgatcattat ttattttcta
    61261 ccagttatta cacaagtatt tcatcaatat tttggttaag aatacgagag tttgtgacaa
    61321 aagtcatgtc acaaactttt ttctttgtca ttttttcgta agaaaaagca aaataaaagt
    61381 atatacattg attaaaagta tatacttgga tataatgtac ttactataga atgagaatgg
    61441 tatagagggt ggcgaaatat gaaaaaaatg aaaaagtata aaattagaaa atctggcaat
    61501 agcgatgtaa caactatccc accagaagta aaagaattca tgggtgtgca gacaggtgac
    61561 gcaatcagtt atgtttttca atctgatggt tctgtacgaa tgatcaaagc acaagaagaa
    61621 cctgatattg attcattagt tgattcgatc atgaatcaat atgaagacgc gttaaaagat
    61681 ttggttgatt tatgaggtat ctttcgacta aagaaattat caaaatcaac gcgaaagtta
    61741 ttttaccgtc actcgccagg cgaaatgatc ggtgtaaaag atgcaaatgc attagatatg
    61801 gccgtcaaac agccttcaca agcagtattc aatcaagaac tctatcctga aatctatgaa
    61861 aaagcggcga ttttagcaat taatttagct aaaaaacatc cttttcataa tggcaataaa
    61921 cgaactgctc ttgttgccat gttgttgttt cttcaattga ataattgtcc agttgctttt
    61981 tctcgtcaag aagctgttga ttttatcata atgattacca ctagttcatt ggatttcgat
    62041 tcactaaagt ccaagataac cagttattta cgacaaaccg caataaaatg aacgaattaa
    62101 aaactttatt tctcaattag atcagcatgt cattaaggaa tatgctgatt tttttatgtt
    62161 taatcataca aaatagtttt ttcataaaaa tatggaaaat atggattaat tttgaaataa
    62221 ttgatttaaa aggaatacaa aagagtgaat agtaggaaat agtggtttag aactagtggg
    62281 ctgatttttt atatatttta gtttacataa tatatattat acaaagtaga tttaaaaaat
    62341 gataaacctc tctcgaacgg ttttttatca aaaatcgtca tttttccatc aaaatctgct
    62401 tatgcaaaat tataaaaaaa ttttgcagtt tttcttactt tttttgtcgt ttaattgaat
    62461 gataaaaacc agtttcttta ttcagttaat caaatatgaa cgaattagat atgaatcatt
    62521 gtatttgccg ttgcggaagg attttttaat taaccacaga taaacattga taacgattcg
    62581 cttattgtaa tcaacagatt aaatttcata tgttcatatg tacggataca ttttcggacc
    62641 gattaatttt aaccattctg tttatttgct tacctattag atatcaataa aaaactgctt
    62701 aacagctatt tcagctgtta agcagtttta ggatttttag ttcatattca ttgtttctta
    62761 taatacagtg ttcaatactt ctcttaaagc acttgttgat ttgctgaaca ttgctttttc
    62821 ttcttcgttg attgataatt caacaacttc acgaacacca ttttcgtcaa cgattgatgg
    62881 cacacctgta aagatatctt tttcgtcgta ttcaccagtt aaataagcag atacaggcaa
    62941 tacagcttgt tcgttattca agatagcttt tacgatacgt gcagtactca taccaatacc
    63001 atagtaagtt gcttttttac gatcaatgat ctcataagca gcattacgga ctttatcagc
    63061 aatcacatct aattcatctt gggcaatacg atggtctttt tctacaattt caaacactgg
    63121 tttaccaccg acagttgtat gtgaccatgc agcaacttct gaatcaccat gttcacctaa
    63181 gatatagccg tggacgctgc gtgggtcaac ttttaatttc aatgcgattt ctttacggaa
    63241 acgagttgta tccaatgttg ttccagtacc gataacacgt gatgttggca gaccagattc
    63301 gttccaagcg atatatgtca aaatatctac tgggtttgaa gcaacaacga taataccgtc
    63361 gaatcctgat cccatgattt cttttacgat ttggcgcatg attgacgcat ttgttttaac
    63421 taaatctaaa cgagattgac caggtttttg gttgatacca gctgtgataa caacgatatc
    63481 agcatcttta cattcttcat agccacctga ccatacagcc acattttcat cgccccaagc
    63541 cataccatct aaaaggtcca atgcttcccc ttctgctttt tcttgattca catcgatcaa
    63601 tactaattca ttagagattc cttggttgat cattgcataa gcgatacttg ttccaacaaa
    63661 acctgtaccg acgattacta ctttacgact tgtttttttc atgaataaac agctcctttt
    63721 cataactatt tgttactttc atgaaaagta tagtcttgtt tattcatttt atcaacatgt
    63781 taattataat agttgttatt ataatttttg atggaaacga attcctgaat acgcataaca
    63841 gataaatgac aaatgtttac acctatatcc cctgataata caaccaaaag tttagaactg
    63901 aaaataaatc caaaaaaatt cgctgcaacg atataataag acagcaatcg cacctaaaac
    63961 aattttcctt catatgcttt agtgaaagat tttcttctta atgtttattt ctccattcat
    64021 tgggagtaca tgttgaatac ttcttgaata atttgaataa agaagtcgtt tgtttatatc
    64081 cgatacgatt agcgatttct tccaacgaaa aactcgtttc ttgaatcagt tccaacgcaa
    64141 agtcgaattt tttctttaga accagttctt gaaaggaagc atcaaaatac attttcaatt
    64201 tattactaag atagaccgga ttgtagccaa aatgagctgc tgtttctttt aacgtacaag
    64261 aagtaaaatg cttatcgata taatctaata ctctaagcat ctcattttct gcgcatccat
    64321 ctgctgatga aaagctttgt tgttctaata aatgagtcaa ttcgatcagt aatagtgatg
    64381 tatagagatt taacgaacgg atcttatgac tgtatgtatc aaaataaatc aacagcatat
    64441 tttcaatcaa atgcgtcaaa cgacttgttt ttccgccgcg aaaatgaatg aattgtgtat
    64501 gttccccttt ttcttttgat gcatttatca aaaaagaaga aagtagatta tttgtgcttg
    64561 ccaaatgatt caatatctct gtagataagg tttcttcttt taataagatg ttgattaaaa
    64621 tatcctcttg ccctgtgtat tcgattcttt gagtagcttc tttatcaatg atcaccacgt
    64681 cactttcttc catctctatc ctttctccat taataatttg taaacatgta ccgctataca
    64741 tataattgat ttcaacaaaa tcatgtgtat gctcgggaac ttccgcatat cgacggtgtt
    64801 tactgatatg aatatttccc tgttgaaata gatcccctcg gtggattttt ggcggtgtct
    64861 gaagatggta agctaagttt aaatcattga tattcattcc ttgttcacgc tgcagagttt
    64921 cgattgattc ttcgttacgc aaaaaaaatg tctaattcag ctagttccaa ttgactccct
    64981 cctttttgta agcggtttct ttcgcttatt agttcacgct gtactgctat tatatgcaaa
    65041 gctatttttg gtttcataaa gactttctat ggttgggaca tgaacttcct gtgattccgc
    65101 tattgagaga ataaccactt catactatat ttttgataag cgcttacaaa aatgaaagga
    65161 acatgcttat gaataaaaag atgatgaaat tttctctgct gtcagtctct cttattttga
    65221 cttctgctgg tgcagtcacg tctgcaattc ccagtatgtc agctacttat gccacgcgtt
    65281 ctttatctgc tgttgaatta ttaacgactg ctccctcttt tatggtcact atttttgttt
    65341 tgattagtag ttttattgct aggaaaatcg gacaaaaaca aactgtgatc atcggattag
    65401 tgattgcatc gatttgtggt atcctccccc tcttctcaca aagttacagt attgtcttag
    65461 cttcaagagc tggactaggt attggctttg gattgatcaa ttctttggca gtcagcatga
    65521 ttgctgcctt ttatcacgga gatgaacgag cctctatgat tggttttcaa agtgcatttc
    65581 aaggatttgg tgcagcttta atgacatttg ttgcaggaca gctagtacag ttcggttggc
    65641 aatatacctt tttagtctac gccatcagct tacctattct tgtcttgttt gttttgtttg
    65701 ttcctacacc tgaaacaact gaacttcaat cgcatggcac agccccaaca agacaagtaa
    65761 tcaaaacgaa tcctaaaatg attagttatg gtatttttct cttgctggtc atcgtggtat
    65821 ataatgctgt atcgattaaa ttagccacag tcctgacgac ttattctcta ggaaacgaaa
    65881 ctaatgcagc gaatatctta acaatcatgc aattggcaag tatggctgcc ggagtttgtt
    65941 ttggctggct tcagacaaaa gcacatcgct atatgcttac actttcttta ctactgatgg
    66001 gaatcggctt tgtattgatt gccactgtga taaacctgta tgtgattggg tttggtgcga
    66061 tcctaacagg aatttctttt tcgttattca ttccttactt attcaaccaa gtaagtatcc
    66121 aagcgcccaa gtacgcggag agtttcaata cttcaatctt attggttggc gctaatttag
    66181 gtactttcat tgcaccatat ggtttgctct ttctctcttt tgcttctctt gggagtaaaa
    66241 cacttgctgt tttcgtcaat ggcagtatct tgctgttgat tagcgcgctt attagccttc
    66301 tagtagtaca caggacgaat agaaagacag tgataagagt agatgaagaa ataaaagaac
    66361 aattgacaac aaaataaatt tgatggaggt cgtgtaaaat gacaaatgaa aaacataaag
    66421 atagatggct ttggtatcct ggagactttg agatccgcca tggactgcta caaaatttcc
    66481 aacgggaaga acgaggtttt gactggccag cgtactggta catggatgat tgccatcgga
    66541 acgtcaagtt taagagatat tactttcttg atcaaccttc catgtttaaa gtgacgatcc
    66601 aaggagttgg gtatgtagaa attaatggac aaaaacatcc atgtggaaaa tggctgactt
    66661 gtccagctgg taaagcaaaa attcgtatct ttgtaggaca tacatcaggg ctaccagcga
    66721 tgtttatcga gggagacgaa gtaaaatcag atattggctg gacagcaagt aattttattg
    66781 aagaatatcc agctggctgg agtccgcttt atgtcgatat cgcaaaagat ccaaatcaaa
    66841 tctattatca aaaagaatgc gtccatccag tcactgaaac ggagattggc ggaggaatct
    66901 tattcgattt tgggcgagca gtgaatggct gtgtagaact aatatctctg gatgaccata
    66961 tcgaatctat cactctatgt tatggagagt ccgatgtaga agctatggat atcgattatt
    67021 gctactataa gcaaatagga atgacaagaa aaatgaaagc tcgtaaacgc gcttttcgct
    67081 atttgtttat accagaggtt tctactggaa tggttcaact tcaagttttt catgaatttt
    67141 tatctctttc gaaacaagct gctttttcaa gcgattcttc tttactgaat cagatctggt
    67201 cagtatcaga agaagccttc aagttatgta gtgatttgtt ttttatcgac ggtatcaaac
    67261 gagatcgctg gatttggtct ggagatgcgt atcaatcatt catgatcaat caatatcttt
    67321 tttttgacga ggaaatcaat aaacgaacga tattagcatt aagaggacaa aatgaaatca
    67381 agcagcatat gaatactatc gttgactatt cgatcttgtg gttgattggt atcgaaaacc
    67441 actatatgat gacgaaagac tatgaatttt tacgcatcgt ctaccctaag atgcaatcat
    67501 taatgagata cttgatggag caaacgaatg aattagggtt tatttatggg agagcaaaag
    67561 attggatatt tattgattgg tctgaaatgg ataaagaagg aacgcttgct gcagaacaag
    67621 tcttattact gaaagcctat cattccatga tcacttgcgg agatatctta gctgaaacat
    67681 atggagagaa cgaaaattat catactcatc tctatcaaga aaaatatcaa ctattgaaac
    67741 aaaacctatt tgactacttt tgggatgaag aacttggcgc ttttatcgat tgctatgaat
    67801 ctgggagaag aaatgtgacg cgtcatgcga atattttcgc tgttttattc gattttgcta
    67861 acaaagacca acagcaatcg atcttaaaga atgtcttatt gaatgacact atcacacaga
    67921 ttactactcc atatttcaaa ttctatgaac aagatgcttt atgcaaactc ggacagacga
    67981 atatcgtcta ccaaacgatt cttgattatt ggggagggat gttatctcat gatgcggtaa
    68041 ctttctggga agaatacgac cctactcaaa caggaaatga aaagtacagt atgtatggag
    68101 atccttatgg aaaaagctta tgccatgcat ggggagcaag cccaatctat cttttaggac
    68161 gctattttat cggtttgtat ccaacaaagc caggttatga agaatttatg atacaaccta
    68221 atctagattc atttgaaaca ctgaattgta cgctacctat caaagatgga aagatttcgc
    68281 ttgaaaaaac aaaagataag atcgtgatta cttctgatag aacaggcgga acagtgaaaa
    68341 tgaatggtaa aagttatcct cttctagcaa aacagccact tgtcttaaca agctattcaa
    68401 aaataaatgc ataaaacaaa aaactgcttg cgacatatca gaagacttta aatcttcttc
    68461 tgatattgtc caagcaattt ttattttgaa gtttgcttaa ttctgttctt tagaaacaat
    68521 gtttgttctt tttccggcaa aaagaaagct agataatacg acaagtaaaa agaaagcgat
    68581 gattccaact gtcaaggcta tttgaccgta ttctcctagt ttcccaagta caagtcctgg
    68641 tactagataa tcagtatcgg caaatgtaga agaagcgatt ttaagatctc ctaatactgg
    68701 aaggataaat aatggcagcc aactaatcaa taagctattg aaagcagaac ctaataccgc
    68761 ccctcttcta ccgccagtcg agttgccgaa gacaccagaa gcagctccgc agaagaaatg
    68821 tcctactacc ccaggaatga taactgtagt ttgcaagcct atcatagcaa acatggatag
    68881 tgttcctaca aagaagctaa caaaaaagcc aattaataca gcattaggtg catatggaaa
    68941 aacgatagga acatctaatg ctggtttaga atcgggtacg agttttttag caatcccttg
    69001 gaatgctgga acgatttctg ccaacaccat tcgaacccct tgaaggacga taacaaaccc
    69061 agctgtgaat gttccagctt ggatcagtgc aaagattaca gcgttgtctc cattgcttag
    69121 ttctctttca acaaatccag gaccagctaa caaagcaagt gcgacatata cgatcgacat
    69181 caagagcatg atcgatacag tagaatctcg caaaaagctg aaacttttag gaatctttat
    69241 gtcctctgta gaacggtctt tgtttccaaa aaactttccg atccatccac tagaagcata
    69301 accgatattt ccggtatgcc ctaacgcaac ttgattgttt ccagtgatgt tcttcataaa
    69361 cggttgacaa agagcaggcg taatagttaa tagtgttcct tcgaagaccc cgcctaataa
    69421 gatcatccac aaatttgcag taaaccccgc gcttactaaa atgactgctg ttagacaaga
    69481 aacataaagc attgcttgac ctgtaagaaa aatgaattta tatcttgtga atctagcaag
    69541 taaaatattc acgatcatcc ctactagcat gatcaaagca gtaggtgtac cgtattgttg
    69601 caaagcaatc gccactactg cttcattgct aggaactact ccttgagtat gcagagctgt
    69661 ttggaacatc gaagcaaaag gggttagtga attactgatt aaaccagcac cgccgatcag
    69721 tactaggaat ccgacaaatg ttttgatagt tccttggatc acttctgaaa atttcttctt
    69781 ctgaagaacg agaccaagca gtgcaatcaa agaaacgagg atggagggct gactgacgat
    69841 tgacacaaac aaattcaaca atttatccat tgatagttcc tcccttgaat catttttatt
    69901 cttttgacaa gatcttcgtt actttttctt ttacttcttc gctgtcaatg atcgattgca
    69961 aaggtacgag cttttcatca ggtatagaag ttagcgtatc tttcaaagaa tgctcaatga
    70021 agaaataatc agccatatcg ctagatacac ttccaacatc cgtatgactt acttcaaact
    70081 cgtccacatc tgctccaaga tctgcaagtg cttgtttgat gttcatctct accataaaac
    70141 ttgttcctaa tccactttga catactgcaa aaattttcat atcattcgtc tccttttctt
    70201 atgatcgcta atatttcttc ttttgttgat gcgtgtaata aatcttgaag attttgttta
    70261 ttagaaagta gctttgttaa atttgccaaa gcccgaagat gtgcctcatt atcgatagca
    70321 gctaaacaga tgaacaaact aatgggatgg gctggattat caagcagatc cacaggttgt
    70381 tgaagtttca gcaaagacat ccctacttcg tttacgccat cttctggacg agcatgaggt
    70441 aatgcgatgt gatcgccaat atggataaac gcaccatact gctccacgcg ctcgatcata
    70501 gctttgatat aactttcttc tattttattt tctgataata gcggctgtgc ggcaaatgtg
    70561 attgcttctt gccagttttt tggttgatcc gataattgga tcatttcttc tgttaataat
    70621 tcagatagca taggacgttg atcctccttc ttttctaaaa gtttgttcat tttacgattt
    70681 aatacttgat agagcttttc ttcgtctacg ccttctttta attcgatata aggcagtagc
    70741 gccgacaaca attcttgggc agaaggcatt gaaaatcctg gtatcagcca atctctttgt
    70801 acttgattga tcagctgatt tttttccaag tcagtcatga ttggatgcag aacatagaga
    70861 gactttttct tatcagtaag tgtgagaggt acagtagaaa aaataatatc gtaagaagtt
    70921 tcgtcaacct cgtgtaagcg gtcagctgaa ttagtctctg taaaaaagat catcgggaat
    70981 aattgctgaa gttcactttt taagatcaat gaagagctaa tgccacttgg acagacgatc
    71041 acggctctta tttttctatt tctttcttct gcgtccgctt ttctgatctc tccgccaaat
    71101 agtatagtga aaaaaccaat ctcttcttca gggatgctct tccctattcg tctttctaac
    71161 ggaagtaatg cttttcttgt catttcgtag atggaagcat attgatgctt aatttgatcg
    71221 atcatcacat taggtaaata aaaagaatag gaaatacgaa aataggcagg gaccaagtga
    71281 taaaagacat tcatcaataa ttcacgaaac gaagcaaatt ctacggccat caggaattcc
    71341 atgcgatgga tgacttctga agaacattcc agcaaaaaat caagtgcagg ctcctggaca
    71401 tctccttcaa cgatcgatgc taagcaaaga gagaaaaata taatctccga attttgatgt
    71461 tcggaatagc caaggccagt caatacttgt cgactaatgt cagtgactgc aagagaagcc
    71521 aacagttcag catcttttac cagttccatg gatgtttttc caattcgaat ggttgtcaaa
    71581 ctcaaataat aagctaattc atccattcga tttggtgcga atcgaagatc tgatagtgaa
    71641 atcgttttat ctagcaaatc tctaactttg gcgtaataat caatggaaag ggttgcggtt
    71701 aaatacgtga gcccaaatct tccagcaagt gactgcatca aacgagcagt gcgatttttt
    71761 gcttctcttc ttaatattgc ttctgaccct agcagcctaa aaccagtttt cctagtatac
    71821 gacagctgac aatcttccac ttctaattca tttcttatct ttttgatatc tgacaggact
    71881 gtccctttag aaacctgaag aaaatcttga aaatgaaaaa cagaaacaga cgttgcagtc
    71941 gaataaacca tcaaataaag aagatctctt cgctcttgtt cggtatacac agcttcaaat
    72001 cgagtaatat ccaaaaattt ttctgcccag tcgattgctc ggaatttctt tatacggata
    72061 cgggtatcat ccacatattc ggcaaaagga gttaattgtt tgatcgcctc gcttgtattt
    72121 acttcgatga tctctgctgc tttttctaga ctgatttctc ttggtgtttt caggagataa
    72181 ctaattttgt agttcacagc gctgttcacc tcctacttat attctagtat ggtagcgctt
    72241 ttaaatcgag gggtgtttgg tacaacttac agttggattt tttttacgac tgtaccgaac
    72301 gatttctatc gaatggatac agaaaaaaag caggtgacca aatgtctcct gcttttatga
    72361 attgatttcg tccgatcaat gatgatcatg tttatttttt gaggtcagtt cttcaaattt
    72421 ttctttgaca tcttcaaccg ctttttcgat atctttttca aagtgattgg gctcattagg
    72481 ctttgtttcc tcttctacag aatttgaacc agataaagct gtttctttat tttctgtttc
    72541 accagagttt gtgccagcta atgattcttc tttgtcttct gtttcaccag aattagttcc
    72601 tgctaaagcc acttcttctt ctgttttagg ggccattgaa cctcttaatc gtttgtgttt
    72661 ttcaccgtca taatttgtca tgttggttcc tcctagtagt tctatacttt ttcatcgtac
    72721 aataagacag tttatgcgtc aaaaaacaaa cccgattctt acaaatatgt catatttttc
    72781 cttctgattc ttgaatgctt ttgattcctt cttccaaaat tttcatttgt aagattgttt
    72841 cttcatcttt gatgactttt tctgcgccat taactaatgt ctcgtaaatc ccttcgtaga
    72901 cacggctgta atcaccaacc tcggaaatta ctttttcttc atgataactc ccttgttcat
    72961 ctatataggt caatacacca taatgttcgg gcaaatcgat accaaagtct tcatgatcag
    73021 gcatgtaaaa cattttcaga tgttcttctt gtcgatcttt tgtttgtttc acgaacatcc
    73081 ctttttttcc gtaaacgacg aaacttggac gttctttgat gcggaaataa ctggatttta
    73141 tcgaaatttt catatttcca tagaaaaaat ccagatcgaa gtaatcattc attcgtcctt
    73201 tccctaaaag ttgacgtaca tcatagctga tatcatctgg ttcgccgaaa taagaaagaa
    73261 cttgatctac tgtatgacaa gcatgtccat ataaatagct gttcgcagta gaaaattcat
    73321 gcgtattttc tggtacttcc ggtctgaaat aatcataatg catttctact tctaaaatat
    73381 cccctaattt tccgctttcg attacttttt ggactgtcaa gaagtcagaa tcgaaccgtc
    73441 tgttttggta acattggata aatagacctt tttcttttgc taatgcaaat aactcttctg
    73501 cttcctttga cgtttctgca aaaggtttct ctactagtac attcttacca tgttcgagtg
    73561 ccatttttcc atattcataa tgaaattgac taggtgtagt gatgacaact aattggatct
    73621 caggatcatc ccaaagatca gacagctgat cagtatattc gatgtcttcg aatgttttcc
    73681 acactggttc agatggggaa aaaatttttt tgatattgat tttgttcgta agttttcttg
    73741 aaaaaggcaa atgatagcga tttgtactct ttccattgcc aagataagcg attgtaagca
    73801 tgagtggtgc ctccttttat tgatgttttc agtatatcct agaaaagcgc agaaagtatt
    73861 tataatagct attctggtaa aaaagttcag aaaaacactt gttatcattc ggtttggtga
    73921 aattaatgtt caaagtaagg ataaaaatca aaaagatagt agcggaacca agtgtttatc
    73981 agtaagatag aatttggagg tcagatcatg cttattgaag aaaaactaac aaaacaagag
    74041 ttgtttacca cgacagagaa acggattgtc gattacatcc gtaggaatat cgaagctgca
    74101 gtctacatga cgattgaaga attagcaaaa gctacgtata cttcccattc agctatcatt
    74161 cgtttatgca aaaaaatggg attcagcgga tttaaagaat tccgtttcga gctggggcgg
    74221 gaagttcatc aattgattgc tcagttcaat caaacgattg atcctaattt tcctttttca
    74281 agtgaagata gcactcagca aattgcaaag aaaatggcgg atttatcgat ccagtcaata
    74341 aaaaaagcac aattgcagat tgaacatgaa gatttagatc aaatcggtaa agtattgaac
    74401 aaggcacagc gaatctttct ttttgcaaaa ggtgattctc aaatcacggc aaggaaattc
    74461 cagaataaaa tggtcaagtt gaataagttt ttgatcatgg ctgaagaata cagtgattct
    74521 tcttggaatg cagccaattt gactagcgag gattgcgcca tttttattag ctacagcggt
    74581 cgcatccatc attatgaacg aataatgacc tatttgaagc atgtagaggc ccctaccttg
    74641 ctgattaccg gaaatcagca ttcagaaatg gccaaacagg ctgatatgtg tcttgttata
    74701 tcgcaggagg aatatgattt tgctaaagta gcgactttct cctctcaaat tgccttcgat
    74761 tacgtattaa atacgttatt ctcagtgata tattctcaaa attttgaaga gaatatccgc
    74821 aacttgaaaa acaaacaaga attgatgcaa aaaggccttc ttaaagaata tcggaaaact
    74881 taagaaaaga tcctcattta gtaataagaa agatagtgtt tgataggctc tctttgatat
    74941 catcataaaa acaggctgaa gttttctttt tcaaacctca gcctgtttgt ttacggaacg
    75001 attcgaatag atatattata gaaatgagga atagctaact tctgtttctt attttgaacg
    75061 attgacgaaa aagatatata agaaggagga aaatcagtat acatgcagct aacaatccat
    75121 acaggaaaaa tcgtttgttc tcggatactt tctgtacttc tttttgaact tcttttgcat
    75181 gataaggaac ccggtgccct ctgacaagta agcgatgact gttgaccata taaggtgtac
    75241 aagttaggag tgtcacgaaa tcctgccctt tttcgattct cagatctttt gtatcagtcg
    75301 gttctaccgt cttgatctga tcgacttgat aagcgagtgt ccgtccattg atttcgatat
    75361 agaaagaatc acctaaagtc agtttcggta agtctgtgaa caactttgct tgaggcagtc
    75421 ctcgatggct ggaaataacg gcatgtgtat tttctccccc cgtaggataa gacgttcctt
    75481 ccaataatga ggcacctttt tctagcagca cagtattcgt ttcatcaaaa attggcaaat
    75541 ggacattgat ctcagggatc gtcaaaatac cgatcgtatg tttctcaaaa taggttctat
    75601 cctttttcgc aggttctttt ttcttagtaa agggatctgc acctggattt ccaccttctt
    75661 ttgctaattg ctggtttttc tttgtcatgt tttcttggat tttagccatg acttcttcat
    75721 tttctttgac cgcttgttgc tgataatgag agatgatctg ctgatccaga taattattca
    75781 gcgcgtcgct aacaaatgga taagctagta tccctattcc tgagagaagc aagaaaagca
    75841 tcagcagatc tagaagtttc cttttctttg gtttcatttg tgttctcctt gtgatgactg
    75901 tttgataata aaagaaaaag gagcatttgc gtaatccgct gctccttttt ccaattcttg
    75961 caaaaagact aaatctgact gtgcttgcgt ctagcaaagt acagtccagc aatcagtaga
    76021 aggactactc ctgcaccgat atacacatag attcccttac cgcctgttga aggaagtgta
    76081 cctttgtgtt tatttggtat tttttcagga gaaatcaact gtcctgctgt tacataagat
    76141 tgttcatcga tagtaaatgc tacacggttt gttaatggaa catatttttc tggcgctttc
    76201 gtttcttcca gatagtacgt gccatatttt agacctgtca catcgattaa accgttactt
    76261 gtggttgtaa aaaccgttgc tgattctttc gccgataccc agctgacggc ttttgtggat
    76321 gggtcgatcg ataaatattt cgctgtgtca ctatcttgat cacgaacgac gaattctgct
    76381 ccagcaagtg tttggtctga tgtaacgtca ccatctactt taacaaatcg tttgccccca
    76441 gtaacgacat cgactgacgg tggtgtttga tcatttgtat gcccgttatc gacatttgct
    76501 tggttagaaa atcctttggt tggatctgct ttttcgttca aatgcatata gtaaacgaat
    76561 ttcaatgtac cgccaggagt taatgaagga atataattcg gatcaactga aaccgtgaat
    76621 ccgtctgttt gctcagtgac agaataattt actgggtcga tttctttatt tccatcatat
    76681 aaggcataag catacgttcc tgaagaatca ttatcaaatg ttaaagcagc gtcatgagta
    76741 tcgataagtt tgaatgttgt gtacttgttt tgcgttcctt ctttatcagc gatacctaat
    76801 gggatattga cagaaatctc atattgaatt ttttcaccga ttgcgacatc ttttccattc
    76861 aattgaggtg ttgttttatc aactttagac gtatcatttt tgatggtctt ttctactggt
    76921 gtttggctat ttgccaggat ctcaaaaggc gtgattgttt gcttttcaat catttccgca
    76981 ttatcaggag cttttacttc ttctaaatta tattttccaa cttctaaatg attaacgatc
    77041 aactggcctt tttcaataga tgcctcggca aagtcattgt tgccgatgtc ataagaatga
    77101 ccagtaatga aatgtttggc tttggtttga tcagttgtcc aagtgtacaa tccatctgtg
    77161 acactttgga tgtatttttt gacgcttggt gttccttctt ctttagaaat aataaattct
    77221 gctccattta gtgcttcgtt ttcggcagta ccgatttttg taactttcaa cgttccatca
    77281 ttaccgactg tatttttagg gtagagatgg atagtatcta gttcttctgt cccgtattta
    77341 taagagccat ctgcttgttt gatcatctca tatacaggga aagctaaaac catgtttgcg
    77401 gcagctgaca ctccgtcttt tggttcttct ttgatcgtgt agactgcatc tttcccattt
    77461 tgttttttag gtaaagataa agtgacattt ccatcagcat ctgtcgttcc tgaagcaact
    77521 ggtgtaccag gagtcaaaga ctggactgct tgttttgctg catccacgga cgctccttta
    77581 tctcgttgcg cataaaattc ttgagtgacg ttataaactg aaaatgaaat atcggctaat
    77641 ccttggtatt gatcgaattc gctcatttct ttcccgctgt tttggattaa aggatcgggt
    77701 aaatcagtca ttttcttttt atgaaggatg acttgagctg ctgtctcctc tgcaaacact
    77761 ttttttgcgc cgaagctgtt tgtgagtaat ggtaaaataa ggaaaaggac tcctaacata
    77821 acgtttattt ttttatgatt tttcattttt tcactcctgt tctttttttg ataaacaacc
    77881 agattgcaaa gcttgcgaat accataccaa caacgcctaa aagtgtattt ttcgtttcgt
    77941 ttgtttttgg aagaaatgga cggctatttt cttttttatt gactactttc aatatactgt
    78001 ccgcctcttt atcctcagaa agaaaagttg aaatggtaaa cggaatttct gtttcactta
    78061 aaatataacc agaaggtgct tcgatctctt ttaatcgata acttcctgtt ttcaacccgg
    78121 aaattgaaaa agcgccattt ttatcggaaa tcaggtgaag cgcatctgat tcgttctttg
    78181 tccacttgta tccgttggct gtttgctgga ggtaatttcc tgctttgttt ttaataagga
    78241 atactgcgcc agctaatcgt ttatctggtt tatttgtctc gattttgaca aattgcttac
    78301 tccctgtata tacagagact ttctttgtac tgacaccaaa accaaaatcc agtgttccgt
    78361 tgttgttgat ttccttgttc gcctgtgctg tactgcttag ctgcatctga taagaaatgg
    78421 tcagtttttt tccagcatat ttttccaacg aagggatcga aaataaaaca tcaaatccgt
    78481 gaggtttctt gtgtatgaca aagccttctg tcagcttttc tccattcgat gaaatcgtta
    78541 aactattagg taaaaacgtt aatgcttcat ccgcactatc tgacaattcg aacttttgat
    78601 agtcaaggat atttacagga attgtcgtat gcaaggaata agtgattttt tcaccaatcg
    78661 taaaatcatt tctaggctct tctaatacct tctcaaaagg tggatcaggg tagtcgtttt
    78721 cttcattttt aggatacaaa tggatagttg aaagtttttg attgttttgt ccatgtacag
    78781 gaagaacaac taccatattc tctgcctttt ctttgacgac ttctggtact ttggattcaa
    78841 tgaaaagata cgctttatct cttttttctt gatctttagc ggccagagaa aaagaagcga
    78901 taccatcttc gttgttaaga gttgtagttg ttgcttctgc ggtaaacata ccggaagacg
    78961 caccgttttt tgcgatctct gcttgtgctt cttctaccgt tttgcccttt tcccgtagat
    79021 ggtaaaaaga atctgtgaca tcataaactt ggaatgtgac accatttaat cctcgatacg
    79081 tttgtaataa agctttttct tgtccgtcat ttggatgatt tttcggcagt tgcccgtttg
    79141 ggaaaagcaa tttgtgtaaa gtaatctgaa ccatttctgt ttctgtttct gttgctacct
    79201 gagtaaaagc tggtttaaat agtaacaaga agagacacat actaagccaa ccaagttttt
    79261 tcatatttag ctgccccctc tttctttttt caaaaaaaga taccaaatag aaaacgcaca
    79321 accaatcatc cctactagat agattcctaa acggccaatt cctcccgttt caggtaatgg
    79381 tacttttgcc tgattcgtga tgtctaaaga aatctggttg tttttggctc ctggtgacag
    79441 aacagattca tgatcttgtc catccacttg aattgaccca tcttcgtgta taactatagt
    79501 aactggctct tttagacctt ggtatccttc tggtgtaaaa gtttcggtca gcgtataagt
    79561 tccaggtttt aaattttcga atagaaaggt atctgtttct tgtccatctt ttggcgattc
    79621 taagtccatt tctggtccct gcagtctgaa ttttgctcct tttaatgtct gtccgttgtc
    79681 ttcttttttg tgtaccgtta gatcaaacgc ttttagtcga ttttgatgag tgagcgtcca
    79741 tacattattt gtcatctcgg tattttttcc cgtgtaaatg atttttccat atttatcgat
    79801 ttggaattca taatttcccg gcgaagtatc atatccggca ggaccagctg tttcaacgac
    79861 tcgatattta ccaggtgtga gtgaatcaaa actggcaaga cctttttcat tcgttgtttg
    79921 gctgtcaatt ggctgataag taccatttgc ttcttttttc tgtagggaaa atgctgctcc
    79981 tttaagattt atctctttgt ccgtcccttg catcgcatac ttacgtactg ctacaggaac
    80041 ttcaacaaaa ggattttcaa tagtcaactg gatcgtatca tcggaagtag tgactgtttt
    80101 tccatcaatg gttaccgtac catcagaagc gatcttgatt tcccaagtag tctttttgct
    80161 taatccatgc ccttctggag cttttgtttc tgtcagcgta taggtcattt ctttttgcaa
    80221 tttgacattt tctggaagag aataggttcc gtcgccatga tctgttagta aagtatcaat
    80281 agaatctcct gttaatttga aaacagcgcc aataagatcc ttttcacctg tagaggaatt
    80341 tttcgttatt ttcaagttta acggtgtgaa ttgtttagta tttttccatg tcattgcatc
    80401 tatttgttga gaatcgtatc ctggtacagg taattctttg attgtttggt aactgaatgc
    80461 ttgaccttga ttattgtatt gaggtagtga taatatctct tgataacttt ctccgctatt
    80521 tgcagataat ttgtcaatgt ctgcacgttc ccacgtattt gttgtatctt tagctggttt
    80581 aatgattcga atatatccgt ttttccaagc tgcagcattt gtcgtatgtt cccgttgaat
    80641 ctcaaaagta acttgatctg gacgatcagc tagattgttg tcaaattctt cccataactt
    80701 tttgatgtga agactgactc cgggagcttt agcagatggt ataccgaatt cagctaattc
    80761 attggtatca atgtttggct ggaaagttgt cctgccgttc atttgatacc agaaatttgg
    80821 atggaagtcc tcattttctg tttggattct cacttggtaa tggatttgga tttcttggtc
    80881 ttttcctaaa tagatctgat tgctcttgat ggtatttcct tctatggaaa tagatggagt
    80941 gaccgttgta ggacttgtcc ccacactctt gactgaaagt gtaccaggct gataaatgaa
    81001 tggttctgcg attggatcat ttatttgtcc attgcttaca gttgctgaga tctgtacagc
    81061 ttttttggct aggtattcag agatatctgt tgcatgatca gctgattcat agtaaagatc
    81121 gcctttttca tctgatgaaa ccatttgtcg catacgagac tctacttctg cttttgagag
    81181 accagctgcc ggatcgcttt gaagttggat gccaagacca tgtatttcga ttcctcgttc
    81241 tttgagtgcc atcgcttctc cgatggttgc gataaacgta ctgtcgattc ttctggatag
    81301 attgttttgg tcaggtgcat catagattct tgagattaga gaagtatttc ccggccgatc
    81361 ttgcgtatta gaaaactgag ttccgtaata attgctgctt gattgtgcgt gtacccgctg
    81421 tactttatag gaaaatgttg gtacaccatc cgtcagcaaa acgatcactt ttttatgtcc
    81481 atttggaacg gatagcatgc ttcctgcatc tcttagtgct ttttgtgtaa aagtaccacc
    81541 atttgtccgt gaaggtgtaa tggattttac ttgatttttc actgaatcaa atgaacccat
    81601 ctgtactgca ccgttactgt agctatatcc ttcgcttgag tagccgacat atcccatatt
    81661 gattttgtct gtgataccgc tatctgctaa agtatcgaca aaacgatcga caccaatctt
    81721 tacttcaccg atccgattat tgtcgttcat acttcctgac cagtctacga ccaatacgag
    81781 atcaagaggc gtgatatctt tttgtacatt tccacgagca ttcaaataaa catcaaacaa
    81841 tccgggtgta cttgtttcct ttgcatactt tcgtatcgca tagtctgctt gattaccggt
    81901 tcctccatat tcgatatacg aatgggtccg atcattagga tctccattcc aagaatttat
    81961 accatcccat tgatttgttc cgtttttatt gccttgatga tcaagaacat ttgtatttcc
    82021 tgtaggttgc caactggctt taggataagt gccctgatca tctgttgtat attctgtagg
    82081 aatcgtttga ttagatggca cactcacagc tggcaaggat aatgtaggca atgtaaatgg
    82141 gctgacagaa ttttcgtttt cttttgatga ttcttcttct atttcgtctg gctttggtac
    82201 tgacacatct gtatctttct tattttctgt ctcatcaata atgtcatatt ctttattatc
    82261 gacgatcagc ttgtttgcct ggctgtggta aagtgctgga tcgattggaa aactcagatc
    82321 gatagtttgt ttagtgtttg atgagatttc caacgtaatt ttcccgctat ttacctgata
    82381 agcatagcca tctccttctt ttctttccac atcacttaag taattttcga ctagaccaat
    82441 ttctttttct atcttttcag cactggtgtt attcgcattt agcttgatgt tcagtgcttt
    82501 ttttccagac tgatccgaaa tgacttcagc tgaaattgtt tctaaaactg ttggatcatc
    82561 tgtagtgtct gctattgcag ataatggcac aaagtttgat aaactcaata ttatcagcat
    82621 gaaaataact ttcagtttct tccctgtggt cgtcattttt cccctccttt ttcttttttt
    82681 ctgttttgac gtgaatagtg aaaattatta aaataaacag gcgttacata attttattta
    82741 ttttaatatg ataattatta tacgaagggc gctaaaggga atcacaccaa ttttcatacc
    82801 aattggtttc atttatgaag ttgattcctt cgattaatga gcgtttcatt gaaagaaaag
    82861 ggttgaggga gaaaaacata tgatcaggtt gttggaagga aactatagaa agatggaaaa
    82921 aatcattcga attctgtcca tttctgacaa gtggatgact aaaaaagaac ttgccaaacg
    82981 aattggtagt tcagaatcta catttgtaag gtatatcgaa gagatcaaaa tccgctgggg
    83041 aacggatgta acgattcaat cttcacaaaa attggggtat cgtcttgaac atttgaatgt
    83101 accagcttat ttaaatgttc tgatggaaat gtcgcaaagt tctacaaaca gtcgtttatt
    83161 aaatgagatt attgtcaatc cgggtaaaac gattgagtat tattgtgaaa aaatttccat
    83221 cagccggtct tcttttacac gtaagttgaa acaatgcaat caaattttag aaagctattt
    83281 attaaaagtg atcgttgacc aaggttttca gttaactagc cttaaaagtg agctccagtt
    83341 gcgtatcttt gttacctttt tctttttaag ttactacgga agacgcacgt tgccatttcc
    83401 aatcgaaaaa aagaagatca aagaaattat ggtcaagaat aattgtcaga tgaatttgtt
    83461 tcaggaagaa agcccatatg agcaatcttt ctttattatg tattttgttg tgcatctcat
    83521 gagagaatcc caaggaactc catttgaatg gaaagctgga gactcttatg tacagttgat
    83581 aaatatcgat aaaaaagact tcttaatctt gaaaaatctc ttaggaaaat tgaagtacag
    83641 cagctatata aaagtagtga actattttgt caatacgatt ttttcagaat tttcggagaa
    83701 agaaaaaaat gaaatcagtg agcagatacg aaaaaatatg tcctactgtt cgttttcatc
    83761 cgctgattgc aaagaaaaaa acgaagaata tgttgttcaa ttattaacgc aaatttattt
    83821 tttctcccgt attttcccat acgatacgac tcatttgacg atccgtgcaa cttactttgc
    83881 acagcagatg caacaccgcc agatacgtct atatgctgga tttcgtgcag aacttcaatt
    83941 ttattccact ctactgaatc agaatctgat ttattattta tctagctata tcttttggat
    84001 gcttatcggt aatcctgaaa ttcaccatta tacttctgat aaaaaaatac tgattatcag
    84061 cgacttaagt cttcgacata gtcaatatat tgaagaatat atcagtgata ttcttgctgt
    84121 gcataaaatt cactctgaga caactgctat tactgaagat cagctgtcga aatacaatct
    84181 tctcgagtat gatctgatcg ttacgaatca acccattttg aatgcccatg ttcctcatat
    84241 attgattgat gatagtgtgt cattcgcaaa tgaagaagaa ctcatccgct tattcgagtt
    84301 atgaataatc aaaaaacagc tatgtataaa ccaccctgat aaaaatttca ggacaaatac
    84361 acatagctgt ttctttttat tgtattcctt cagcaatcca acgagattta tagcgaaagt
    84421 cttttaacaa ctcttctttt gtccaattat ttgcaatgag atccgtcaaa gtgttcatta
    84481 cgagggtcat ggaaaagtat aggaaactaa ctgcttcttc cgacgattga atggagaaat
    84541 gattgattct taataattcc agccattttt cgttcattgg agaatcagcc gatagttctc
    84601 tacgtttggt tgtctgctga tcatttcgct gggttaacaa gtataacctt tgccaataga
    84661 tactttcgtg atctaagtcg cagcaccact ctaaatattt ttcgatcccc aaaaagaaat
    84721 gttgtttgtt ttcgctaatg aattttaaga tatcttgatg gactatgtga gaactgcttt
    84781 tgatcgtata caaataagca tcttccaaat cttgaaaata tttataaaaa gcaccgcgcg
    84841 acatccccat cttgtcaacg atttctgaga ctttgacttg gctgatgtgc tgtgagcaaa
    84901 atatctccag taataggtca tcgattctct gtttctttgc gttcgataaa ttgaaaaaag
    84961 tttcttttgg catccacatc tctcctttat ctctgattat acgtggatag cccttcattg
    85021 tcatgaagga ttcattcctt ctttttctct tcttctgtca agtacccatc ttccattcga
    85081 taaacgcgat cactccattg aatcatacgg acatcatgag taaccataat agtcgctttt
    85141 tgtttctcat gagcttcttt aactagtaat ttgacgactt catatgcatg atctgtatcc
    85201 aaactagctg ttggttcgtc tgctaagatc aagcttggct cattatataa agcgcgagca
    85261 attgccactc tctgtctttc tccaccagaa aggtctttag gataactatt tttaagtgac
    85321 tggatatcta aagattgcag caaggaatcg atttttgttg aatcttcttt ttttgaagta
    85381 acttggtcaa ctagttcaaa ttgttccttt accgttaaaa aaggaatcaa attagagctt
    85441 tggagaataa atcctatttc tttaaagcgt aaatctgctc gttttttttc tggaagctca
    85501 gttagtgagt gaccgttgat cactatttct ccggaagtcg gtgtttgcaa tcctcctgaa
    85561 atggtaagga aagtactttt acctgaacca gaaggaccaa tgatgctgac gaattctcct
    85621 tcctttacat aaaaatcaat tgctttcaaa gctgagacct ttgtatgacc agaaccaaat
    85681 gttttggtaa cttttttcat cgttaatatt tttttcattt ttattaacct cctattgctg
    85741 taattgggtc tactttggtt atcgtacgta tcgaaaacaa tccgcctagc attgcgacaa
    85801 tgatcaaaat cccactatat agcaaccatt gtgaccaaaa aacagcaaaa ggcatcgcgc
    85861 ttggtaaaat cagactagtc aaataagcaa acaaaagagc aagcagaacg cctaccaccc
    85921 caacaataaa ggactgtgct actaaagatt tagcgatgaa gaaatttttg atcccttgtg
    85981 ctttcattac tccaaaaata gcagtcttct gaagtgtcat cacgtacatg aaaataccga
    86041 ccacggcagc aaccactaag aacaaaaagt atatcatcgc atttaaggtc atattttggg
    86101 cagaatagcc aggaatactt tcaatgaatg tcccaatagt taataactgt agacccttcg
    86161 atgctttttc tttcgaaatt ttagctgaat cctttattac gatcccattg atcggctgtt
    86221 cttcttcaga agcaaacggc tgttgtccat acttcaaagc agtccacgta tctagggacg
    86281 catagatgac gggagaaact gtgtaataag tttcaggaaa gataccgaca atcgtcaaag
    86341 gatcgtcgta actgccaatt ttgatcgtat ctccaatttt atagcctgaa tcagccagat
    86401 tttgagagat gatgatttca ttctttgttt taaattcatg ccctttcgtg agttttggta
    86461 ataaaaatgc ttctttcgtt gtgccgaaaa ctgtaacatt ttctttgttt tttcctttga
    86521 ttgctccgct gtacaatccg attggtgctt tctctcctcc ttcaatgtat ttcagatctc
    86581 ctcttgttaa ttgtgaagct gcaaatactt gatttgcatc ctccgacaaa acaatctctt
    86641 gtgcgtccca atcatcgatt gcttttttaa actcttctga aagtccattc gctagtcctg
    86701 acaacatgaa tacgacatac gcaatcaaga acataatacc gacgatcaag ccatatcgta
    86761 atttagaata gcgaatttct ttgatagcta gaaacatttg tttttcctcc ctatgataga
    86821 ttgatagtga caaaatgtca cttgttgaat agtgtaactc taaagtgaca atttgtcact
    86881 tgtgttgttt ttttcttatc aataaattgt ctaagacatc tttcgataaa accttaacat
    86941 gagtcataaa aaatttattt aagccttatt tatgctttcc atgataaact aaagtgacca
    87001 aatcaatgag gtgggaaaat gattaaacta ttagtagtag aagacgataa agtattatcc
    87061 aataatataa aagaaatact cgctgcaatc ggcgagataa cacaagttta tgatggtagt
    87121 gaaggactgt tcgagttgga aagtggagtt tatgatcttg caatcttgga tttgatgatg
    87181 ccggaaatga atggatatga agtgttagca aaaatacgga aagaaaaaat acagactcca
    87241 gtattgattt tgactgcaaa agatagtttg gaagataaga ttgaaggatt tgaacgaggt
    87301 gcagatgatt atctaacaaa acctttctat cgagaagaac tgatcatgcg cgtgaaagca
    87361 ttattgaaac gctcgctagg tctctttgat gaaaatgttc tgaagtataa ggatatcagt
    87421 tgtgatttaa aaagcaatga agtcttgtat aaagaacaag ttttgcccat acaaggaaaa
    87481 gagtttgaat tgctcgttta ttttttacaa aataagggaa tcattttgac aaaagagcag
    87541 atatttgacc ggatctgggg atttgattct gatacgacga ttacagttat tgaagtttat
    87601 atgagcaact tacgaaaaca tctgcgaagt actggattgg ataaagaaat caaaacctta
    87661 cgtaatgtcg gttatatact gcaaagggtg tgatgcaatg aatggagata ttacacgaaa
    87721 gcaacgtagt cgcttttttg cgacaaatgt agcagcattt gcttttatct tttttctttt
    87781 gggattcatt actttacaga tattaaacca atctgcatac agagaaacag atctgtcatt
    87841 agagaaaata aattttgatt ctcgaacagt acaattagag atacaaagat atcagcaagg
    87901 cgatcccttt ttaaacccga ctcaaacgga acaaaacaga acaaacatgg aacagccatt
    87961 aatggaacca tcaaatgacc gttttaacac tcaagtgatc ttgtggtcta aaaatggtga
    88021 gatattgaat aaagcagcta ttggtgggcg tttcaaccaa atcaaagaat taaaaatgga
    88081 tacgaaaaat ctgaatacca tccaaaatat tgaattaaat gaagacagtg gctcatctgc
    88141 cctctctttc cgttcgatta cgaaaaaagc ggagacgaat caagatggcg ttgcctacat
    88201 ccaaatttta gaaaatacaa atcaaatcaa gaattcatta gcgacttttc gcacgattat
    88261 gattttgtgt atgattgttt tttggattct ctctattggt atcagttatt acttgtctag
    88321 tctaagcatg cgccctatta ttctttcttg gagaagacaa aaagaatttg ttgagaatgc
    88381 ttctcatgaa ttgcgcacac cgttaacgat tattcaaaat agtttggaac atctttttac
    88441 caagcctaat catactatta ttgaagaatc cgaaagcatc gctcaagcat tgtcagagac
    88501 gaggcgcctc actggattga cttcggattt gctgacaatc gctcggaatg attctgatca
    88561 gcagctgctt tcaaagcaaa tgatcaatac acaagaatat atcgaacaac ttgttaaacc
    88621 atttcaagag atggccatca tagatggaaa agagtttatt ctccataacg atgcaacatt
    88681 agaagtacca attgatgaaa aaaaaatcca tcaagttttg gttattttgc tggataatgc
    88741 attaaaatat acgaatccag aagataagat cattttggat tcatctgtta accataaaga
    88801 atggctgatt cacgtaaaga atactggccc ttctatcagt gaagaagatc aagcaaggat
    88861 ttttgatcga ttttatcggg aagatcaatc tcgggcgaaa gagactggcg gatacgggct
    88921 tggcttggca attgcaaaac aggtaatcga acagcatcat ggacagattt ctgtatccaa
    88981 ttatcttcca caaggagtcg attttaaagt ccaattgccg ttgaagccta aaaaataatg
    89041 cttatcccta aaaaagggct gtgacaaaaa tcttgtcaca gccctttttt gttgcgaata
    89101 aacggtgttc cagaagtagc ttcttcggaa ataagccgaa atttctttaa gctgaccact
    89161 tctgtcacaa cctctttagc ttacgcttac gattttttat tgcggtcttc aatgtgtaca
    89221 tcaccgcttg tgtcaatatc caattcttct cggctaacat cttctgtcac tttttcaaca
    89281 tcttcatgtt cttctttatg aatcccaact tcttcacgaa taactgtatg tttgcttaca
    89341 tctacttgct cttctttgat tgggatagta atcgtgtcat cttccaattt ttcgtctgtt
    89401 ccctgtgaag attgatctgt tactggtttg cgttcgatga cgatttcttc acgtttgacc
    89461 ggtacttcta ccgtttcagt atcgttgacc acatgtttgt ggatgtcgac ttctccagtt
    89521 gtcacatcat gtgtatttac atctaatttt tcttctttta gttgaattgt atcatcatct
    89581 agatttggtt tgcgatcgat gtcttcagtc ttgcttgtac ccattgtatc agtctcgcca
    89641 ggtacgtcca tcggatcagt tcctggtgtc atattcaatg gatccgttgt attttgaaag
    89701 cctgtcgtgc cacctacgtc cattggatct gttccagtgc cagtttctaa tccagtcccc
    89761 attgtgcttg ctgggctaac agtatcttgt gtatccattg tatcttctgt tgtttctggc
    89821 tgacgatagc cttttactgt gatgacaaat tttccatcag aaatatctcc tctatattga
    89881 tataaaggat cattttctgg tgtagccgtc tcagaatcat aggtatcaaa agaaaaagta
    89941 tcttttattt tttcccataa agaacggtct tcttcaccat ccatccgatt ttcatctgtt
    90001 tcaacatcta taccagacaa tccgtcaaat cctagtctag atgctgcttc atcagtagta
    90061 taaataacga tatcatctcg ttcataccct tcgttacgca accgttcaat tactgataat
    90121 gcttcttccc tcgtactata gcttccgatg accgttaaat ttttctcttc catgtaaatt
    90181 cctcctagca aatagattta tgattggtat attgttactt ataaatttat tctataggag
    90241 acgattgttt tctacaaata tttagattgg aatttgatta aaacaattta attgaaattt
    90301 gaaaacattt atgttaatga aagtcatatt ctaataaaat gtcatttgtt tctatatgaa
    90361 tttttatgaa aaatttcata taatttccac tcgttgtgat ggtttaattt atccaatcca
    90421 tcaataagca aacaacttat ataaaaaagg attaattctc aatataattg ctcctaccat
    90481 agaataaatc ttcatgtaaa gtaatgaagt accaactatt tctaatactt ctttaagaat
    90541 tatcccaaca atatcgttag acaaaccatt attgaataaa tggagagcca atcgattctg
    90601 aaaaaatgtt ttctaatttt tcggaaataa aagaaagagc ctcctgccat tagaacgaac
    90661 caaatccatt tcattgctca tgaagtaacc acatagctaa aaagaggata aatcaattaa
    90721 aagatcaaaa gaatgactgc actaataaaa taactaaaaa tgtatcttct tacttcatat
    90781 cttttagcta gtacttagtt aaaaatttgc ttcctaagat caagacaaac tgtctatctt
    90841 catttgatga aatgcggtaa aatatagaaa atgaacacta ttggagggaa tttgtaatgg
    90901 acagcaaaac tagaaaacaa ctgcaagaaa agttaaagca acgtacacac ttgctccctt
    90961 ccgtctttca acagttttta gaagaaaatc gttcttccct ttcattaggc agtcgctatg
    91021 aatacgcaaa agattttcat ctgtttactg attatttgag aaaagtattt tctgaagaag
    91081 tggatgatca gctgattatc catttagaaa aacaagatta tcagaatttc ttagctaaaa
    91141 tctatcgaca tactcgttcg ttccaaacta cagcgaacca agaaacggag caattgtttg
    91201 aaaatagcta ttacgggatt tcaaggaagc aatattcatt aaatcatttt ttacgatttt
    91261 tgtatcaaaa aggactgatt gaagaagaga tttctctttt gggtacaagt ttaccggaaa
    91321 caaccaaagc agctccgcga tatatcgatg cagaactttt caaagatttt gagcatttgt
    91381 ttatcccgat tgaaggcttt caaacaagca gagaagctag ctttgaagaa aagaatagac
    91441 cgaggaacct tgcaattact gccattcttc tgtattgcgg attaaagatc catgaagtag
    91501 tagaacttaa acgtaaagat gtatctttga ccaagcagat tcttaatctg aatagaaaag
    91561 aaaacagact gaataaagta ccaataccaa aagaagcgat gccatttctg gagaactatt
    91621 ttaagttaac agcacaaaat acggacgaaa attcttttgt ttttcgttcc tcacatgatc
    91681 agcaaatttc tcctcggact attcgccaaa ttttgagcaa aattacagta tataaaaacg
    91741 tatcgccaga actatgcaga aaaacatatc gttattatgc agaactatat ttagatgatg
    91801 ctgacgcggt aaattattta tgtggtaatc gatacctctc atcccattct tttcaagata
    91861 tctgggaaaa gatggttgat ttttcttatc acgaattagc ggcattcgtt cgggtttctt
    91921 ccatataaaa caaatgtatg atctttt
//
LOCUS       DAFTHM010000003        87338 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFTHM010000003 DAFTHM010000000
VERSION     DAFTHM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 87338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.003"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..900)
                     /locus_tag="L7C88_000191"
     CDS             complement(<1..900)
                     /locus_tag="L7C88_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9557057.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLS"
     gene            1083..2207
                     /locus_tag="L7C88_000192"
     CDS             1083..2207
                     /locus_tag="L7C88_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBP9557058.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            2434..3351
                     /locus_tag="L7C88_000193"
     CDS             2434..3351
                     /locus_tag="L7C88_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9557059.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            3344..4177
                     /locus_tag="L7C88_000194"
     CDS             3344..4177
                     /locus_tag="L7C88_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9557060.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            4260..5378
                     /locus_tag="L7C88_000195"
     CDS             4260..5378
                     /locus_tag="L7C88_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBP9557061.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            5372..7270
                     /locus_tag="L7C88_000196"
     CDS             5372..7270
                     /locus_tag="L7C88_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBP9557062.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            7264..8487
                     /locus_tag="L7C88_000197"
     CDS             7264..8487
                     /locus_tag="L7C88_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBP9557063.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(8573..10507)
                     /locus_tag="L7C88_000198"
     CDS             complement(8573..10507)
                     /locus_tag="L7C88_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBP9557064.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            10733..11389
                     /locus_tag="L7C88_000199"
     CDS             10733..11389
                     /locus_tag="L7C88_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBP9557065.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(11463..11816)
                     /locus_tag="L7C88_000200"
     CDS             complement(11463..11816)
                     /locus_tag="L7C88_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBP9557066.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            12008..12937
                     /locus_tag="L7C88_000201"
     CDS             12008..12937
                     /locus_tag="L7C88_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBP9557067.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            12948..13784
                     /locus_tag="L7C88_000202"
     CDS             12948..13784
                     /locus_tag="L7C88_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBP9557068.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            14032..14808
                     /locus_tag="L7C88_000203"
     CDS             14032..14808
                     /locus_tag="L7C88_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9557069.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            14984..15727
                     /locus_tag="L7C88_000204"
     CDS             14984..15727
                     /locus_tag="L7C88_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557070.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            15720..17300
                     /locus_tag="L7C88_000205"
     CDS             15720..17300
                     /locus_tag="L7C88_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBP9557071.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(17551..18030)
                     /locus_tag="L7C88_000206"
     CDS             complement(17551..18030)
                     /locus_tag="L7C88_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBP9557072.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(18046..18798)
                     /locus_tag="L7C88_000207"
     CDS             complement(18046..18798)
                     /locus_tag="L7C88_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBP9557073.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            18915..18985
                     /locus_tag="L7C88_000208"
     tRNA            18915..18985
                     /locus_tag="L7C88_000208"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18947..18949,aa:Gly,seq:ccc)
     gene            19346..20071
                     /locus_tag="L7C88_000209"
     CDS             19346..20071
                     /locus_tag="L7C88_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBP9557074.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            20326..20592
                     /locus_tag="L7C88_000210"
     CDS             20326..20592
                     /locus_tag="L7C88_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBP9557075.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            20589..21020
                     /gene="ruvX"
                     /locus_tag="L7C88_000211"
     CDS             20589..21020
                     /gene="ruvX"
                     /locus_tag="L7C88_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBP9557076.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            21045..21350
                     /locus_tag="L7C88_000212"
     CDS             21045..21350
                     /locus_tag="L7C88_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBP9557077.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(21431..22576)
                     /locus_tag="L7C88_000213"
     CDS             complement(21431..22576)
                     /locus_tag="L7C88_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBP9557078.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(22637..23284)
                     /locus_tag="L7C88_000214"
     CDS             complement(22637..23284)
                     /locus_tag="L7C88_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9557079.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            23478..23771
                     /locus_tag="L7C88_000215"
     CDS             23478..23771
                     /locus_tag="L7C88_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557080.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            23815..24126
                     /locus_tag="L7C88_000216"
     CDS             23815..24126
                     /locus_tag="L7C88_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557081.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            24123..24747
                     /locus_tag="L7C88_000217"
                     /pseudo
     CDS             24123..24747
                     /locus_tag="L7C88_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            24888..25046
                     /locus_tag="L7C88_000218"
     CDS             24888..25046
                     /locus_tag="L7C88_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557082.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            25047..25409
                     /locus_tag="L7C88_000219"
     CDS             25047..25409
                     /locus_tag="L7C88_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557083.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            25446..26294
                     /locus_tag="L7C88_000220"
     CDS             25446..26294
                     /locus_tag="L7C88_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBP9557084.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            26284..27759
                     /locus_tag="L7C88_000221"
     CDS             26284..27759
                     /locus_tag="L7C88_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBP9557085.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            28025..28432
                     /locus_tag="L7C88_000222"
     CDS             28025..28432
                     /locus_tag="L7C88_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBP9557086.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            28435..28650
                     /locus_tag="L7C88_000223"
     CDS             28435..28650
                     /locus_tag="L7C88_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557087.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            28654..29034
                     /locus_tag="L7C88_000224"
     CDS             28654..29034
                     /locus_tag="L7C88_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBP9557088.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            29168..29323
                     /locus_tag="L7C88_000225"
     CDS             29168..29323
                     /locus_tag="L7C88_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBP9557089.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            29392..29865
                     /locus_tag="L7C88_000226"
     CDS             29392..29865
                     /locus_tag="L7C88_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBP9557090.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            29862..31556
                     /locus_tag="L7C88_000227"
     CDS             29862..31556
                     /locus_tag="L7C88_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBP9557091.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            31522..31707
                     /locus_tag="L7C88_000228"
     CDS             31522..31707
                     /locus_tag="L7C88_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557092.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            31711..32886
                     /locus_tag="L7C88_000229"
     CDS             31711..32886
                     /locus_tag="L7C88_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBP9557093.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            32879..34402
                     /locus_tag="L7C88_000230"
     CDS             32879..34402
                     /locus_tag="L7C88_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBP9557094.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            34458..34742
                     /locus_tag="L7C88_000231"
     CDS             34458..34742
                     /locus_tag="L7C88_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBP9557095.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            34729..35064
                     /locus_tag="L7C88_000232"
     CDS             34729..35064
                     /locus_tag="L7C88_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBP9557096.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            35359..35985
                     /locus_tag="L7C88_000233"
     CDS             35359..35985
                     /locus_tag="L7C88_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557097.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            36727..37564
                     /locus_tag="L7C88_000234"
                     /pseudo
     CDS             36727..37564
                     /locus_tag="L7C88_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
     gene            37629..38063
                     /locus_tag="L7C88_000235"
     CDS             37629..38063
                     /locus_tag="L7C88_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9557098.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(38131..39453)
                     /locus_tag="L7C88_000236"
     CDS             complement(38131..39453)
                     /locus_tag="L7C88_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBP9557099.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(39607..41247)
                     /locus_tag="L7C88_000237"
     CDS             complement(39607..41247)
                     /locus_tag="L7C88_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBP9557100.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            41577..42047
                     /locus_tag="L7C88_000238"
     CDS             41577..42047
                     /locus_tag="L7C88_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBP9557101.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            42676..43779
                     /locus_tag="L7C88_000239"
     CDS             42676..43779
                     /locus_tag="L7C88_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBP9557102.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            44063..44743
                     /locus_tag="L7C88_000240"
     CDS             44063..44743
                     /locus_tag="L7C88_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBP9557103.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            44833..45867
                     /locus_tag="L7C88_000241"
     CDS             44833..45867
                     /locus_tag="L7C88_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBP9557104.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            45881..46216
                     /locus_tag="L7C88_000242"
     CDS             45881..46216
                     /locus_tag="L7C88_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557105.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            46200..48680
                     /locus_tag="L7C88_000243"
     CDS             46200..48680
                     /locus_tag="L7C88_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557106.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            48736..50295
                     /locus_tag="L7C88_000244"
     CDS             48736..50295
                     /locus_tag="L7C88_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557107.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            50292..51656
                     /locus_tag="L7C88_000245"
     CDS             50292..51656
                     /locus_tag="L7C88_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBP9557108.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            51827..52897
                     /locus_tag="L7C88_000246"
     CDS             51827..52897
                     /locus_tag="L7C88_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557109.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            52912..53580
                     /locus_tag="L7C88_000247"
     CDS             52912..53580
                     /locus_tag="L7C88_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557110.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            53600..54178
                     /locus_tag="L7C88_000248"
     CDS             53600..54178
                     /locus_tag="L7C88_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBP9557111.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            54581..55492
                     /locus_tag="L7C88_000249"
     CDS             54581..55492
                     /locus_tag="L7C88_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBP9557112.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(55748..56665)
                     /locus_tag="L7C88_000250"
     CDS             complement(55748..56665)
                     /locus_tag="L7C88_000250"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBP9557113.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            56867..57304
                     /gene="zapA"
                     /locus_tag="L7C88_000251"
     CDS             56867..57304
                     /gene="zapA"
                     /locus_tag="L7C88_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBP9557114.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            57362..57909
                     /locus_tag="L7C88_000252"
                     /pseudo
     CDS             57362..57909
                     /locus_tag="L7C88_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
     gene            58024..60384
                     /locus_tag="L7C88_000253"
     CDS             58024..60384
                     /locus_tag="L7C88_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBP9557115.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            60471..60785
                     /gene="trxA"
                     /locus_tag="L7C88_000254"
     CDS             60471..60785
                     /gene="trxA"
                     /locus_tag="L7C88_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBP9557116.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            60967..62745
                     /gene="uvrC"
                     /locus_tag="L7C88_000255"
     CDS             60967..62745
                     /gene="uvrC"
                     /locus_tag="L7C88_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBP9557117.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            62890..63789
                     /locus_tag="L7C88_000256"
     CDS             62890..63789
                     /locus_tag="L7C88_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557118.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            63782..65044
                     /locus_tag="L7C88_000257"
     CDS             63782..65044
                     /locus_tag="L7C88_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557119.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            65207..67105
                     /locus_tag="L7C88_000258"
     CDS             65207..67105
                     /locus_tag="L7C88_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBP9557120.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(67404..68123)
                     /locus_tag="L7C88_000259"
     CDS             complement(67404..68123)
                     /locus_tag="L7C88_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBP9557121.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            68460..68792
                     /locus_tag="L7C88_000260"
     CDS             68460..68792
                     /locus_tag="L7C88_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557122.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            68779..70782
                     /locus_tag="L7C88_000261"
     CDS             68779..70782
                     /locus_tag="L7C88_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBP9557123.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            70801..71271
                     /locus_tag="L7C88_000262"
     CDS             70801..71271
                     /locus_tag="L7C88_000262"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBP9557124.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            71292..71876
                     /locus_tag="L7C88_000263"
     CDS             71292..71876
                     /locus_tag="L7C88_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBP9557125.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            71891..72877
                     /locus_tag="L7C88_000264"
     CDS             71891..72877
                     /locus_tag="L7C88_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBP9557126.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            72867..73178
                     /locus_tag="L7C88_000265"
     CDS             72867..73178
                     /locus_tag="L7C88_000265"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBP9557127.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            73200..74981
                     /locus_tag="L7C88_000266"
     CDS             73200..74981
                     /locus_tag="L7C88_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBP9557128.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            74974..76350
                     /locus_tag="L7C88_000267"
     CDS             74974..76350
                     /locus_tag="L7C88_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBP9557129.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            76357..76992
                     /locus_tag="L7C88_000268"
     CDS             76357..76992
                     /locus_tag="L7C88_000268"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBP9557130.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            77022..78377
                     /locus_tag="L7C88_000269"
     CDS             77022..78377
                     /locus_tag="L7C88_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBP9557131.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(78569..79963)
                     /locus_tag="L7C88_000270"
     CDS             complement(78569..79963)
                     /locus_tag="L7C88_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBP9557132.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            80055..81026
                     /locus_tag="L7C88_000271"
     CDS             80055..81026
                     /locus_tag="L7C88_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBP9557133.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            81023..81805
                     /locus_tag="L7C88_000272"
     CDS             81023..81805
                     /locus_tag="L7C88_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBP9557134.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(81974..82345)
                     /locus_tag="L7C88_000273"
     CDS             complement(81974..82345)
                     /locus_tag="L7C88_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBP9557135.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            82479..82922
                     /locus_tag="L7C88_000274"
     CDS             82479..82922
                     /locus_tag="L7C88_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBP9557136.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(82965..83774)
                     /gene="yidA"
                     /locus_tag="L7C88_000275"
     CDS             complement(82965..83774)
                     /gene="yidA"
                     /locus_tag="L7C88_000275"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBP9557137.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(83793..85160)
                     /locus_tag="L7C88_000276"
     CDS             complement(83793..85160)
                     /locus_tag="L7C88_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBP9557138.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(85144..85974)
                     /locus_tag="L7C88_000277"
     CDS             complement(85144..85974)
                     /locus_tag="L7C88_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBP9557139.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            86137..86574
                     /locus_tag="L7C88_000278"
     CDS             86137..86574
                     /locus_tag="L7C88_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBP9557140.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            86650..87270
                     /locus_tag="L7C88_000279"
     CDS             86650..87270
                     /locus_tag="L7C88_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBP9557141.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
BASE COUNT        28821 a        14722 c        18065 g        25730 t
ORIGIN      
        1 ggatagataa tactttgaag gggataaccc tgtatatttt ttaaaagctg aagaaaaatg
       61 atggatcgaa tgaaatccta atatatctgc aatttctgta taggttaatt cattttctag
      121 cacgagacgt tttgcttttt ccatttttag ttctttaaaa tagctaataa cactttttcc
      181 attcactttt ctaaaatgtt tttttaagct ggctggactg ataaaaaaaa tttgggctaa
      241 ttgttcaagc aaaaaatttt ctgaaagatg ttcttctaaa tatcgtatga ttggatcaac
      301 taattcatct gaataaagaa tatgcttttt tttaggaatg actttctcat ttgaaggtat
      361 tgtcaataaa gcaagttcct gttgataatg ccttggtaag gaagacaatt gaattttttg
      421 cagacaataa gtaactaata aggaaagcaa atgaatgctc atctgttggc atagtatgaa
      481 aaaagaattg atttcctgat cataggaaat agctggctta ctatgtttta gataatcaat
      541 tttgaactgt tcatttttca gaaaagtaat gatagatgtt atttcttgat ctatagaaaa
      601 agattgtccc gtaatatgtg ctaataattg ctcatcaaaa taaaactgga taatgataaa
      661 agtttgtgtt tccttttgag tagaaaagat ttggacttct tgctgtttat caatgaataa
      721 aagggaagga ttatctagtt ctatagattt atgtgcaaat tcagcatata aattagcgct
      781 ttcatttatt agtagtcgaa aatagggagc agcagataaa tgaagatggg tatctatgga
      841 ataggttagt gtttttttga caagattgga ggattggttg tttgttaaca aaagaaccac
      901 tttcctttct ctttttatat aaaaagcttt ctatttataa ttaatgacta ttataacaaa
      961 aatgaaaagc caaaacgaca agtaaaatat ttttttatat aaatatttgt gttactaatt
     1021 ccgttaatat acataagtga aagcgtttta tataagaact tgaaaagaaa gaagggatag
     1081 acatgaaaaa aagatacaaa ttggtgatag ctttgctaaa cattacccta ttattcagct
     1141 taagtgcatg tggaaaaact aacgaagaag taacagcaaa catcgcagat ccaatgataa
     1201 aaaaagccac tacattagaa gtatatgtcg caaacggcaa actgacaaac tatgttgaaa
     1261 atgctgcaaa aatctataac cgcaaaactg gagcaaatat tgacttaaaa attgtgaatg
     1321 tagcttcggg aacagcaaca gtacaaatga tcaccccaaa attggtaaca cacgaagata
     1381 tgccggatat tatctccatg gcagacactt cagcagcagg tgtgctggaa aaatttcaag
     1441 atgcttttta tagtgctgat gaatatggat tttatgacaa atatggcgat cagttttatg
     1501 atcaaaaatt gaatattttg cgtcaacaaa cgagtaatga aacgattatt ccttgggcta
     1561 gtgattttac cccagcactt tgttattatc aaccaaaaaa atttgctgaa ataggtgtag
     1621 attttgaaga aatcagttct tgggaagaat atatccaggt ggcaaaagca ttaaaagaaa
     1681 aaactggtag ttttggaatt gccttgccag aatctgggga ccaagaattg tttatcaaca
     1741 tgctagccca gcagaatcaa tctttgcttg atgaagaagg aaatatccgt ctgaatacta
     1801 aagaagcgaa acatgctgca aagttaatca aagaaatgat cgactcagat attgtacatt
     1861 tctacggtgc acaagatgct gagaaagcat ttcaagaatc tgcaatgttt gttgctggcg
     1921 gctggtatgc tacgaatatg tctttgaatt ttcctgatgc atctgacaaa tggcgcatgg
     1981 ctccactgat tcctttttca aaagaaaatc caggaaaagg tgcagtatca ggaggatcaa
     2041 gtttttatgt ccctaaagat gccaaaaatc cacaagtggc acaacaattt cttacattta
     2101 tgctgacaga tgaagaatgc ttagccaacg cactggagct gggcgtggct acatctaact
     2161 cattggccta tcaaacagaa gcagctgaga aaaagtttga ctactaagga ggacaaaaat
     2221 actatgaact attgaataaa atcaatgaaa atacatcaaa tactgtttta ccagccactt
     2281 attcagatgc tacgtcttat ttgactaccg ctgcatataa ctattggcaa acaggtgatt
     2341 ttgaaaattc atatctaaaa gaagcagaaa attttgctca taagtacggc gtaaaattaa
     2401 ctggtgatta aaaaatatta ggaggactta acgatgatgc aatcttcgtt accaagcaag
     2461 acaataaaga acagcaagaa aaaagcaaca gatacgtctc ataaaaaaag tgcttatgga
     2521 ttggtcacac cttttgttat tttctttatt gtgacgattt tgattcccat cattatctcg
     2581 tttgctttta gttttatgaa aattggctac tcatttgaat ttgttggatt tgacaattat
     2641 ctagctatct tccgagatcc attgtttatt aaatcttaca cgaatgtttt gattatcatg
     2701 gcaggatcaa ttccaataac gatgctatta gctatttact ttgctgtttt attgaattca
     2761 gcacagttaa aaggaaaagg attttttaga actgtctatt atattccaac cattacatca
     2821 acggtggctg tagcttccgt attcatgact tttttcaatc cgactgggtt attcaatgga
     2881 tttttgaatg cgctaggaat taacggtgta cagtggttaa caaatccttt ttggatacga
     2941 atatcaatga tcatcacgat gatttggctt agtgtaggat ataacactat tttattttta
     3001 gctggtcttc aagggatttc taaagagata tacgaaagtg ctgaaataga tggagcatcg
     3061 aaatttcggc aattcttttt attaacgatc cccatgctaa agccaatcat tttaatggcc
     3121 acagttttag ccactatcaa tggcttgggt aatttcaata tcccaaatat attctttggg
     3181 acttccaatg gaccagaaaa ttcagctttg gtcgtaggag tcaatttata taaaacaagt
     3241 tttgaaatgg ttgattttgg aaaagcctct gctattgcct ggacgatggt gtttgtatct
     3301 gttatattat cggctattca atttaaattc ggaggtgata aaaatgacta aacaaaagat
     3361 acaaagcaga atttttacgt acgtcattat tgtgtttggt gccttaatat ttttgatgcc
     3421 atatttatat atgattgtag cttcaacgca aagtaatcaa gaaattttaa gtggcggaat
     3481 caatttcaag tttggggata tgctattaaa aaactggcaa gccatcatgg cgagatataa
     3541 ttatcccttg attatttgga attcgattgt tattgctgta atcagtacag ttttagctac
     3601 agccagttct acaatggcgg gttatgcatt agcaaagtat cgttttatgg ggaataaact
     3661 gttgttcaat acagttatgc tatctaggat ggtgcctttt tttaccacat tgattccttt
     3721 attttacatt atgagtcgtt taggattatc gaatacttat gcaggtgtga tcatcccttc
     3781 gattgccagt acaacttcag tgtttatgat gcgacaatat agcagtcaat ttcctacagc
     3841 actgatggag gctgccagaa tcgatggtgc caatgagtgg gtgattttta cgaaaatcgc
     3901 tgtaccgatt ttatcaccta cgattattac tagtggttta cttatcttta tgggaagttg
     3961 gaatcaatat ctatttccat tagtcatgct ttcagataaa gataaatata cggttccctt
     4021 aattatcaaa aatatgacgg tttctagtac aggtgagcca attaattatg gcgcaattat
     4081 gctaatttta gcaacttcag tgatcccaat ggtcttgatt tatgtgtggg cgcagtctaa
     4141 atttaaggag aatgacattg gagctgcaaa taagtaaaaa aaataacgaa tgttaaccat
     4201 ctagttcgtt ctaggagcaa ctccacattc ataaaaatta aaagaatggc gggatatcca
     4261 tgaatgaaca gacgaaggaa tggtcaagaa aaattttgaa tgtagcttct gaaaagatag
     4321 atgcggaatt agacagaatg gggaataaaa ttccatatat ttcttacaac ggaaaatata
     4381 cagacgtaat aaaggacaga ggaatcgact ggtggaccaa tggtttttgg agtggtattt
     4441 tatggcagct ctttcacaag acaaaacgag aaaagttcaa agaggcagca atacaacaag
     4501 aacaattatt agaatctgcc ctgtaccatt tttcagacgt tcatcatgat gtaggttttt
     4561 tattcttacc atcggctatt gcacattatc aacagtctca aaacaaacat agtcgacaac
     4621 tagggttaca tgcagctacg gtacttgctg gacgctataa tatttcaggg aactatttag
     4681 tagcatggaa tgaccataaa cctggttgga tgattattga tagtatgatg aatttaccat
     4741 tactgtattg ggcttcgagg gaaactggtg atccgaggtt ctctaaaatt gctcggcagc
     4801 atgcagatac aacagctaag tatctagtga ggaaagatgg atcaaccggg catatcgcag
     4861 aatttgatgc agaatcaggg aaatatattc ggttacttgg cgggcaagga tacaatgaga
     4921 attcttgttg gagcagagga aatgcatggg ctttatatgg attcgcgtta agttatcgtt
     4981 acacaaaaaa tccgtactat ctagctatag cagaaaagat agcagtaaat tttattcaga
     5041 aaatcgaaaa aactggttat attcctctca ttgattttgc tgtaaaagat tcgaatattg
     5101 ataccagtgc tggagtatgc gctgcatgcg gtcttctgga attagcagga tatgtttcct
     5161 ctgtacgatc aaaaatgtat catgaagctg ctatcaatat actccaaaag acagaaaagc
     5221 actatgcaaa ttggaatatg gatgaagatg ggatcattgg aggcggagca gaagcatacc
     5281 atagagaact gacttataat gtgccactga tctattctga ttattttttt attgaaggct
     5341 tacttcgatt agaacagtcg gaattagcta tttggtagta aaaagaggag aaaatacaat
     5401 gaaacatcca gtaccactat taaggaccag acaggattac tttgacttat ttaaaaagat
     5461 aaatcaacca ctccagccgt tttatcgagc aagtggcgca caaattgatt atatacatca
     5521 aggggtagga tatggaaata aaattgcagg aatggaagga ttctctcggg ttttatgggg
     5581 agcggggccc gcaattgacc aattagatga acgatggttg aaattaattc tatcaggaat
     5641 aaaagctgga acagatcctt cccatcccga ttattgggga gaaatacatg aaagagacca
     5701 gcgtatggta gaaatgcccg caatgttatt agcgttatat catcatgaac aattattatg
     5761 gaaaaaatta gatacaggag aaaaaagcca gattattcat tggttctcgc aaatttttga
     5821 atatgaatgt gcagatggta attggcaatt ttttaagata attgtcggaa caattatcca
     5881 aaaatttggt tatccagtta aagaatcagc actgaaagaa gcatttgata atatagaaaa
     5941 ttgttatctt caaaatggct ggtatcgaga cagttcaaga ggtcgccaag attattataa
     6001 tccttttgca tttcattatt atggtttgat ttatagcgta ctagaaccag aaaagcccat
     6061 tagccagata tataagaacc gagctattga tttttctaga gactatattc atttttttgc
     6121 ggaagatggt gcaaatgtgc cttttggtcg aagcatgatt tatcgttttg cagtttcaag
     6181 cttttggtca gctatgttgt gggccgatct tttgcctttt aaattaggtg aaatcaaggg
     6241 gttagtcaat cggaatataa gatggtggat gcaaaaagaa atatttgatg aaaaaggtat
     6301 cctgaatatt ggttatacct accctcaatt gacattgact gaaccctata atagtacgtt
     6361 atctccatta tggctgaata agattttttt attgttggcg ctacctgaag accatgagta
     6421 ttggacggct aaagaaatgc ctatgcctat tcgtgaagga actaaacttc tttcagaagc
     6481 caatttgctc atacaacatg ataatggaca tacatttttt ttgaatgcgg gacaattagg
     6541 gccaaatttc catacattga ccaatgaaaa atatttaaaa tttgcttatt ctagtcaatt
     6601 tggtttttcg ataccgcgag cgaatcaatt gaaagcagaa atggcaatgg attcaatgct
     6661 agggattcag cgagcggaca catatatcac gaccagtttt aagaatgaga gcatcaaaac
     6721 ctatggacag ttcatcgttc gaaataatgt acgagacatt gtatgtaaga aagaggtact
     6781 tgcctctaca tgggaaccta ctttacaggc aaaaatcaga acttggctta ttccttttga
     6841 aggctggcag attcgcgtac acaaagtaga attagataca gaatatgttc tatatgagac
     6901 agggtttgct attgaatgtt ctcctgagaa agaaggaata atcatagaag aagacaagga
     6961 aaactatagg gtgagtgaag ctggcttttc aggtattatc tgtttaagtg acgatactat
     7021 taaacgaaaa tccacagcta ttatgggttt gcccaataca aacttgatga catgggaaaa
     7081 cacttttatt cctggattag agggtacatt tggaaaagga acccattggc tcggaacagg
     7141 agtggttgct catcaagatc gggattatag tttagaagta tggaacaatc gtcccaaaat
     7201 tgattttgat gggacaaccg ggctaactat ccaaaataaa aacaataaaa aaagactaaa
     7261 attatgctaa aggctggtgg ggaaatgctt gataaagtga tgtttgaaga gataatacat
     7321 ccagaaaaat ggataaatga atgttataaa gaattaatgg aaaaagaatg gaataatgag
     7381 atcgagcgtt gtcgcagaca cacggagagg ttaatcaaac gtatcagtaa cagtcagtat
     7441 caattcccaa gcgagtgtcc tataaaagga cgttatccat taagagacaa tattggttgg
     7501 acagaaggat tttggacagg aattaattgg ttgttatttg agaagacggg tgatccttta
     7561 tttcaacaaa cagctgaaaa agcagatata gattttatcc acaggattga ctgtcaaatt
     7621 atcactaatc atcacgatct tggttttttg tattctttat caaccgtagc agattataaa
     7681 ataacgggaa atcgaaaaat gaaggaagct tcaattgatg ctgcagaaac attacttcag
     7741 cgtttttggg agaaggcagg agttatacaa gcttggggag atcctagtga tccttcacaa
     7801 caaggtagaa tgatcatgga ttgttgcatg aatcttccat tattgtattg ggcgagtgaa
     7861 gaaactggaa atcaaaaata taaaaaagct gctcaggctc atattcaaaa tgcagcagat
     7921 tatttagtaa gagaagatgg ttcaacttat catacatttt atatggatgt caaagatgga
     7981 aaaccaagat atggaagtac gcatcaaggt tatagtgata attcctgttg ggctagaggc
     8041 caagcatggg ggatttacgg ttttgcatta agttatcgtt atttgaaaga acaaaaatat
     8101 tttgatttaa gcaaaatatt agccaattat tttatgaatc ggttgccaga agataccatt
     8161 tgttattggg atttgatctt tgatgattct agcagagaag aaaaagatac atctagtatg
     8221 gtgatcatgg tttgtggatt attagaatta atagaatcag gtctattaga caaaacagaa
     8281 aagaacttat accagtctgc tgtttggaaa attatgcgac aattgaaaga aagatatgct
     8341 acaacggaag aagaagatgg ctttttaaca cagtctgttt ataataagcc caaaaataat
     8401 ggggtaaata caccttgtat ttggggtgat tactattatt tagaagcttt agtgagaatg
     8461 actagtaatt ggtcttctta ttggtgaaaa aggtaaatat ggaatttttg tttgataaaa
     8521 taaaaaaaga aaaaccaaaa cagcatgaat ggtttctgtt ttggtttttt cgttaatttt
     8581 catattcttc taattccaag cttagttctt cccattccgt caattttgtt tcttgatctt
     8641 gtctagcagc ttctaaatct tggttcagct cattgagttt tacgtgatct tccaggtttt
     8701 ctggcgcgac catttcttgt tccaactgat cgatccattc atcgatccgc gccatttctt
     8761 cttcaacctg agtaattttt cgttgaaggc tacggataag cttttgctgt tctttgcttt
     8821 ggtaataatc agatttgttc gtgggagcag gagcagattc tggctcatct tgtgccaaca
     8881 attcggcgat ttcttcttct tcctgctttt tctctaaata ataatcatag tctcctagat
     8941 agactttgct gccattttca gagagttcga cgacttttgt cgcgatccga ttgatgaaat
     9001 atcggtcatg ggaaacaaaa agcagtgtgc cgtcataatc gatcaatgca ttttctaata
     9061 cttctttgtt gtcaatatct aaatggtttg ttggttcatc caaaatcaaa aaattttctt
     9121 tgttcatcgc taacttggct aaagcaaccc gtgctttttc accgccactt agcagaggga
     9181 ttggtttttc tacatcttcg ccagaaaata agaaagcacc taaagcactt cggatctctt
     9241 tttctggagt ggtaggatgc tcatcccaca attctgctag gatcgtcttg tttgtatgca
     9301 gatcagcttg accttgatcg taatagccga tggtgacatt tgtccctagc gtttcttttc
     9361 cacggataaa agggatctgg tgaatgattg atttcagcaa cgtcgatttc ccgataccat
     9421 tcggacctac tagagcaatc gcttcttgac gacggatatc tagattgatt ggttcagata
     9481 aggtgacatt atcatatccg atagcggcat cttcgatttg caagactaca tttccagaag
     9541 gcttttctat actgaataga aagtttgctt gtttttcatc cccttgagga cgatccagcc
     9601 ggtccatttt ttctaatgtc tttctgcggc tttgcgctcg ttttgtggta gaggcgcgaa
     9661 caaggttccg agcaacgaag tcttctaatt tatggatttc tgtttgctgc ttttcataag
     9721 ccttccattc acttgctaac tgttctgctt tcaaatctag atatttcgaa tagttacctt
     9781 tgtaatggcg catttttctt ctgcttaatt catagacttc attgactact ttatctaaaa
     9841 aataacggtc atgggaaaca atcaataatg caccagtata gctttgcaga taattctcaa
     9901 gccaggaaag tgtctcgata tctaaatggt tcgttggttc atctagaatc aaaatgtcag
     9961 ggtgttgcaa aagcatgcga gctaaagcta aacgtgtgcg ctgtccgcct gataaagtat
    10021 cgattttctg atcataaaat gaagaatcga atttaaaccc atgcaatacg gaacgaattt
    10081 cattttcata accatagccg tttcgatctg aaaaatcgtg ttgcagccgg tcgtattctt
    10141 ttaaataaga actataagca ggtgtgtctg gcgtaccttc gctaatgaaa atctctagct
    10201 cgcgcatccg ctcttccatt tgtctaactt gttcaaaagc tttcagcatc tcgttccaaa
    10261 ctgtttcatt ggaatcaagt cctgtgtcct gagcgaggta tccgagagtc gctgttttat
    10321 ttttagcgat ctttccttca tcaggtgctt caattccagc aatgatcttt aataaagtcg
    10381 attttccagc gccatttctg ccaactaaag cgacacgagc gcctgtactg atttctaaat
    10441 gtatgttttc aaataagact tctgcaccaa aatggcgagc aatctgattg gcttgtaata
    10501 atatcatgga atcctctttt ctactttgtg aattctcctc aaataaaaaa ctatttttca
    10561 attagtagtc taccataaat tccattatac tgcgagattt gcagaaatga taaataaatg
    10621 aataaagaat aaaatttcac aatatctgag caatggaatt gattttttcc tataaatact
    10681 gctatgatgg agaaatcaaa gatgtaatta gacaatacgt ggaggtcatt tcgtgaaaga
    10741 tcatattatt ccaaaggcga cagctaaaag actgcctttg tattatcgct atttaaggat
    10801 tttaaataat gctggaaaga aaaaagtgtc ttcaactgaa ttaagtgaag ccgttcaagt
    10861 agatagtgca acgatccgtc gagatttttc ttattttggc gaattaggaa aacgtgggta
    10921 tggttatgat gtagaagatc ttatgcactt ttttgcaaag acattaaacg acgatcaatt
    10981 gacaaatgtt gcgctgatcg gtgtagggaa cttgggaagt gctttactaa aatacaaatt
    11041 ccatcaaagt aatagcatac gtatcagttg tgcttttgat gtgaatgagg aaatcgttgg
    11101 gcgcatcgta gacggtatcc ccgtttatcc aatggaagat atgtcagaac aaatcaagat
    11161 ccaacaaatc gaagtagcaa ttttaacgat acccgctgaa agagcacaag aagtagtcaa
    11221 tcagttaacg gaagcaggaa tcaaaggaat cttgaacttt accgctgctc gattgaatgc
    11281 tccgtcagat gtattgatcc aaaatgttga tttgacgaat gaattgcaaa ccttgatcta
    11341 tttcttgcat tctgacgcaa atgcgcattc cgaaaataca gcagaataaa aataaaaagc
    11401 gattgaacaa atgaaggcaa aactttcact tgttcaatcg cttttttctg tttggacaac
    11461 gattattttg ttcggaagat ttcttcataa gaaagggaat catcttctgc tgtcagttca
    11521 tctagtagat aacggatttt tttaaagtcg atgaaccgtg cttgccgaaa gacttctttt
    11581 ccttgatgaa aaatcaggac aactggcgca gtcagcactt caaatttact agctacttct
    11641 ggtgtttcaa atgcatccaa atgaagtgcc ggaatatcat aatgtgtgag aagttcctct
    11701 agtcgtggac gaacagcgtg acaaacactg caattaggca tcgaaagata aatgacggca
    11761 acggatgact gttgcagtat gtcttgaact tcagtcaagt tagtggtttg tttcattttt
    11821 attctccctt ttatgataga agtgatatgt atgagacctt aatttaatgg gaataacaga
    11881 aaaagtcaat tgaagtgctt tggtaaaaaa taagagttgt gtaaaaattt acagagcaac
    11941 ttgttttttt tgaataaaag cgtatatttg caaagcgaat gaactagaaa taaaaaggag
    12001 gaaactcatg ttttctttta ttccaaattc ggttttgcag atgagtacga ttttcttatc
    12061 gatcgttatt gaagcattac ctttcgtatt attaggctgt cttatctcag gcgccttaca
    12121 agtatttttg accccagaac gtgtgaagag atggcttcct gaaaatcgta tcttctctat
    12181 ttttactggt tcgatcttag gatttttctt tccttcatgt gaatgcggca tcgtaccgat
    12241 cgttcatcaa tttgttaaaa aaggcgtacc agttcacaca gcgtttgctt ttatgctgac
    12301 tgctccgatc atcaatccaa tcgtgatttt ttccactttt atcgcatttg gcaattcttg
    12361 gcagatggca agctggcggg tgataggcag cttttttgtt gcccttgtga ttggtgtctg
    12421 gcttgcctat tttcaaaaag acgctgtatt gaaagaaaaa atcacgtcta aagtagcaga
    12481 aaatcaccat catcatgtcc atgaagaaga acaaagtgag aagaatgaac caaaaaatca
    12541 gctgatccat caaactgggc atgtgttgac acattcaatc gacgaatttt ttgatacagg
    12601 tcgttatttg atcattggcg gattaatcgc agctgcgatg cagacttatt taccaactag
    12661 aattatgcta acgctcggct caacaaagat tttagccatt atcatcatgc tgttattggc
    12721 ctttacgatg tctctttgct cagaagcaga tgcgtttata ggatcttctt tgttaagtct
    12781 gttcggcaca gcacctgtag ctgccttttt ggtctttggc ccaatggtcg atatcaaaaa
    12841 tctactgatg atgaaacgat attttacagg acgctttatt ttatcgctga tcggactgat
    12901 tgcccttagc gttattggat tcacattatt tatttaggag ggaaaatatg ctgcggtttt
    12961 tgattttatc tgggtatttc gaattgatga tgtacttgca agtttctggc aaactcgatc
    13021 aatatatcaa tgtccattat cgctacttag ctattctttc aatgatttta tctgctcttt
    13081 tggctttagt tcagctgtat ttgtgggtca aaaacggaaa agcagaagaa aaggcacacg
    13141 agcacgatca tgaccatggg ttgtcaaaac cttatcaacg tggaatcgct tatgtactgc
    13201 tagctttgcc agtaatcgtg gggacgttgt ttccaacagt tagtctcgac actacgatcg
    13261 tagaagccaa aggatttaat ttcccagtaa gtaaagaatc agtaggggat ccggagatgc
    13321 agacacaata cttaaagccg gataccagta tttatttcaa caaatcagac tacttagacc
    13381 aaatgaatga gttgaaagaa aagtatgggg ataagcaaac tatcaagatc acagatgaaa
    13441 actatttaga agttatggag ctaatttata attaccctag cgaattcatt ggcaaaaaaa
    13501 tcagctatga aggatttgtt taccaaacac cgaacgatag caatacagat atcttcttgt
    13561 tccgattcgg cattatccat tgtgtggcag attcaggagt ctttggtttg ttgacgcata
    13621 tgccggaagg agtaacggtt aaaaatgatg aatggtataa aatagaagga accatccaat
    13681 cagactatta tcaaccattc aagcgtgaaa tcccatctgt agttgttaca aacgctgaga
    13741 aagtctctgc tccgaaaaat cagtatgtgt atcgttcttt ttaaaagaac aaaataaata
    13801 aacatagctc agacagctga cacgcaagga cgtcggttgt ctggcttttt ttgcatgatg
    13861 tattcatttg tttgatattt attttagaag cagcatcctg aaagtatttg atatcggttt
    13921 caaaggtgtt ggaaaagatt gtgaagagaa ttacaattta ttcctaacat gtatgttgaa
    13981 aagttgtatg aaatgatttt gatagtaaaa tatcgagtgg aggtactttt tatggtaacg
    14041 cgtatattta ttttggatga tagtttggtt tttgaaaaaa tgctagtaga aattttggaa
    14101 gaatccagaa ttttattaag tccttggaaa tttgagatcg ttcagggatt gaacgttata
    14161 caatttgttg aattcattaa aaataatgaa atctattcct cagatatttt tttcctagac
    14221 atcgatttga acgcctatta tagcggtatc gaactaggcg aaatgcttag agaaaagaat
    14281 gaaaagtgta aaattgttta tctaacgtct catccgaata aagcaataac tgttattaat
    14341 cgaaagatta cgcctagtgg ttatttgata aaagaattca cttatgaaaa aaataaaaaa
    14401 agcatccaaa gttacttatt gaaagaaaaa gaaaactatc ctgttcaaca tgctacgaaa
    14461 aaaaggtgga caactgtccg ttatggtaat agcgatcact atatccatta cgatgaaatc
    14521 ctttatctaa tgagcatgcc aggttataaa aataaaatag gcctagtatt gaaagatgaa
    14581 gagattctcg taaacggcac aattaaaaaa tataaaaaat cactcgaata tgagtattta
    14641 tgtaaagatt taaaagctta tatcattaat actgaaaaca ttacatctat tagcagagta
    14701 aacgaaatag taacatttgc aaatggagaa caactagaga tgggaaagag aagtattgat
    14761 aaactaaaga attttatgca agaaaagata gaaaatgaat cattttaaag aaaacaaaga
    14821 ctcatatctt acctgttaga agagtgtttt cctgtagaag agaacaaccc aagtagcagc
    14881 ctagtcgttt ctatcctttt ttgttatgca ctctttttga catttactcc accaataacg
    14941 aagggtacaa taaaaagtaa taacaaacaa aaggagtaca gaaatgattg aattcatcaa
    15001 tgtaagtaaa agttacggga aaaaacaagc attaaaagac ttgtctctct cgataagaca
    15061 aggggaaatt tttggatttt taggacataa tggtgccgga aaatcaacta cgattaaaag
    15121 tttagttagt attattgaac catcatcggg aacgatttta gtagatggaa tgaaattgac
    15181 ggaaaatcga ttgagtatca aacaaaaaat cggttatgtg cctgattccc cagatatttt
    15241 tttacaattg acggctggag aatattggga cttgatttca gctgcctatg aattagacac
    15301 acaaaaaaaa gaaaagcgtt tagcagaatt gacagcgctt tttgatatgt atagtcatca
    15361 aaatgaaaca atcgcaagtt tttcacatgg aatgcgtcaa aaaacgattt tgatcggcac
    15421 gttgctgcca gatccagata tttgggtatt ggatgaacct ttgcaaggac ttgatcctca
    15481 agcagcattt gatttgaaag aaatgatgaa ggctcatgcc gcaaaaggaa aaacagtcat
    15541 tttttctaca catgtattgg ataccgcaca acagttatgc gataaactgg ctattttgaa
    15601 gaaaggtgaa ttgatttatc agggggcagt tagtgaatta ttgaatggct cacctgatga
    15661 aacgctagaa aagatttatt tgaaaatggc tggaaggcaa gcgacaggag atggaccgta
    15721 tgtataagcg acaattatta gaattaattc gagttaatct tttatatgtt aatccacagc
    15781 tcacgaataa agcaagagag aaaggaaaaa agggaaagcg attaactatc tatcttttgt
    15841 ctcaaaatct tttttcaggg ctgatttttt tactgattta cggatttgct atgtttgcta
    15901 tgaactttgt taaattgcca ggtttcttta cttattacgt ggcacttttt ggtatgttag
    15961 gtttaactca aagtatatca gtcatttata atatcttttt tgaaggaaat gacctgcaag
    16021 tatttttgcc tctgcctttt ggacaagaac aggttttttc agcaaagatt ttggtagttg
    16081 ctttgaccat cattcctttt gtttttccgc ttctagtcat gtttatttta accggatggc
    16141 gagctgatct agggattttg cttactatca ttatctcaat ccttttgttt tctctatttt
    16201 tgattattct tttttgtctg gctagtttga ttgtttttgg tttggctcga acagcagtgt
    16261 ttaaaaaaca tagaaaaaca gtttctagta tcttgcttgg cagctcgatg ctgatcgcat
    16321 ttgctggaat catgtggatg aatcatcaaa cggggactat tgaaaatgag ttaacagatc
    16381 ggcatccgat ttcgatatta ttgccattct atgatgctgc cagtcagcca ctttctcaac
    16441 aaggtttatt gggttgggga atactagcta tcacggctct gggatttttc cttgctgtaa
    16501 aacagctgat agtaccaaag cttacagagc aactgactga ttcaaacagt gagttcaaaa
    16561 taaaaagaac ccataaaaag aaccaaaatg tgcatcagct tttatttagt tacaatgctc
    16621 aattagtaaa agaacctaat ttgattatgc aagttctttc ttcttccttg ttaactccaa
    16681 tcatttttat tcttgctttt gccctaggag gcgaaataaa attaactgat ttagataata
    16741 agttaatcgg tgttgttttc ctggtaggga tcgcattggc tttcttaaca gttaatcaga
    16801 cttcttttat cagcaatctt atttctttgg atcaagaaaa ttttctgttt atccgttctt
    16861 tgccaatctc tatgaaccaa tatttaaaag aaaagttcag attcggatgg atattgcaga
    16921 gttttttaac tggtgggatc gcattattaa gcggactgtc ttttcagctg cctttgtttt
    16981 ttatccctag cttgctattt ggttctttat tcggctgcta cttattgtca ctacgttatt
    17041 tcgctagaga ttatcggttg ctgctgctga actggaccaa tattaaccaa ttatttaaca
    17101 gaggttcagg aagtttgggt ttagtcgcaa ctatgatggg ttcattgatc atcagtatta
    17161 ttcttatcgt cttatacgga atgttggctt tgttttatcc attttggtta gtgaatattc
    17221 ctgtgatcgg tttagttcta atactttccg ctctatggat cgtttattat caacgaacgt
    17281 tttggaaaaa atttgaataa agaagagggg ccgtgacaaa aatcatgtcg cagccccttt
    17341 tttacagata gagggtgttc aaaagtcagt ttctcagtat taagtcaatt ttatgtaaaa
    17401 atgtgagaag ctatttttac aaaacttttt ttaatactca taattacttc ttattgctcc
    17461 tgcggttact tgtcgcaatg tttgtgagat attttgtcat cgctcaaggc tgaacgtctc
    17521 tttcacaacc ttttctttgt tacacttcgt ttatttaaaa agccgttttt ttcgtttcat
    17581 catgattgcg tcacgcttta ctttgaaatt acggatgtta tggttaaaga cttctgataa
    17641 tacaagacct aaagcgattg ctccagcaat cataattgct tggaccgcat aatgagccgc
    17701 ttctcgatag gattcagtaa cgagatttcg aaccgcttga taagctaaac caccagggac
    17761 tagaggaacc atcccgggaa tattgaaaat cgttacgggc attttcaaac gtttagagaa
    17821 aagatcgctg atgaatgcta ctcctaaaga accaagcaat gaaccaaaag cagcagatcc
    17881 gcctatttga acacagatcc agtagatcat ccagccaaaa gcaccagaaa gaccacaaca
    17941 aatcaatgaa cgcctaggta catttgtaat aacggcaaat gccgcagtcg ctaaaaaact
    18001 aaaagaaaac tgaataaata tcgtccccat acttgtgttc ctttcctaat aaaaaagctg
    18061 gaaaataaaa gcaatcgcaa aaccgatcat cgtagcagtc atcatcgctt ctgttccgcg
    18121 agaaactcct gagacataat gtccagctag caaatcacgg atagcgttcg taatttgaac
    18181 tccaggaact aaaggcatca cacatccgat aatgattaga tcctgattgc ttcctaagcc
    18241 aaaacgtacg ctgtagatag cggctatgcc aatcaataaa gaagataaaa attccgataa
    18301 aaatttgatt ctaaaaaatt tcaaactata tagataagct gcgtatccca atcctccaat
    18361 gactaaagtc acaggtaaat cggtcatctt tccgccaaat aacaccataa ttgttccact
    18421 gatcactgcc gcgctaacga tttgcaacca gacaggaaag aaagaacggt ctcggtcgat
    18481 tgcttgcagt tcgcagtaaa gttcttctaa tgttagctct gaagcaacat atttacgtga
    18541 aagatcattt acttttacta ctttttctaa attaatcgaa cggttggtaa tttgttccat
    18601 tcggatggtc gaggtacgat caagaccaat aaagagaccg gtttgagtga catagctgac
    18661 caaacggaaa tttccagaag ctaaagcaat tcgactcatc gtatcttcta cccgatacat
    18721 ctccgcattg ctttccatca tgattttccc agcgagtaaa caagtgtcca gcaacagatc
    18781 taattctttt cccgtcatag catcttctcc aataattgat tgattagttt tattttacta
    18841 caaaacatac cagaagcgta aagaataaaa aaacttgagg aaggaataaa agaggcgtat
    18901 actgtttttg tattgcgggt gtagtttagt ggtaaaatcc cagcttccca agctgatgtc
    18961 gcgggttcga ttcccgtcac ccgcttaaaa taggttgtga aaaagctgct ctgcaacaag
    19021 taataagaac agccaagcaa aaacaacttc ttatgttttt aacttggatg gacttattac
    19081 cgcagatgca agcttttgcg caccgtttac caagcggttg tgaaatcagt gtattgtctt
    19141 gagtatgaag aaaatttttg aataataata aataccttac agatagagtg gtgactgatt
    19201 agagacgagg aatccgtctc ttttttgtat ttttaagcca tcttaaaaca ggttttattt
    19261 tttgctgttt ctatttcttt ctagtattta tttatagggg aacatatgtt aagatttagg
    19321 gagctgttag taaaggagta aagaaatgag caaaaaaaca accaaggcga tcgtggggat
    19381 cgtcgctgct gtgattgcag gggcattcgg tgtttccacc acacaaaaag attcagatat
    19441 ctttcagcag attacaacta tttttgattc cacaccacaa gcttctcaag tagcggatgt
    19501 gccagaatat gatggaaaac atcaagaaat agaaatcaat gggaatcagc cggaatttac
    19561 aaaagaggat cttagccttt ccaaaggaac atgggaaagc tattcaaata ttgataaatt
    19621 gaacagagta ggacaagcca atgctatgct tggaaaagat ttgttcccta ctgaaaagag
    19681 agagcctttg tatattgacc cgacaggttg gaaacaaaag aaattaagtg acgggcaatg
    19741 gttatataat cgcagccatt taattggttt ccagctgact ggtcaaaata acaacattaa
    19801 aaacttgatg acagggacac gttcgttgaa tgctccatac atgcttgctc acgaaaatga
    19861 tattgcggca tatatcaaag aaacaaatca tcatgtacgc taccgtgtca ctcctcattt
    19921 tgaggggaat gaactggtag ccaggggagt gcaattggaa gcagaaagca ttgaagacaa
    19981 aaaaattgaa ttcaatgtct ttatctacaa tgttcaagat ggctacacga tcaattatga
    20041 gacaggacaa gcaacaaaaa caaaaaatta gtagcagcta ttcgaatttt ttatgaatat
    20101 tatgaaaaaa ttgtgtaaaa acatacattc aaagaaatat agcgtatact ttatgaaaag
    20161 agtacttttg ataaagctac agaaaaaagg aaaaaaacat acaaatagtg tttcttaatt
    20221 tattcggaag tttggaatat ttgtttgtag ttttcccttt cttcgagtaa aataaggttg
    20281 tagaaggtaa gctggaatta ccttgcggga aagaggtgta gaatcatggg ttttacagat
    20341 gaaaccgtac gttttggttt tgacgatagt cgcaaaaaag aagtgagcga aacattagcg
    20401 attgtttatc gggctttgga agaaaaaggc tacaatccaa tcaatcagat tgtcggctac
    20461 ttgctttctg gagacccggc ctacattcct cgttatcgtg atgctcgaaa tttgattcgc
    20521 cgtcacgaac gcgatgagat catggaagta attgtcaagg actacctctc aaatcatgga
    20581 gtgaatttat gagagtaatg ggcttggatg tcggttctaa gacagtaggt gttgctatca
    20641 gtgacccctt tggctggaca gctcaaggag tagagatcat tcggatcaat gaagcagaag
    20701 aagagtttgg ctttgatcgg ttgaaggaat tagtagcaca atatgaagta gaccggtttg
    20761 tagttggatt acctaaaaat atgaacaatt ccatcggacc aagggcagaa gcttccatgt
    20821 catacggaga aaagatcaaa gaactattct ccttgccagt tgattatcaa gatgaacgat
    20881 taaccactgt tcaggcagaa cgtatgctag tagagcaggc aaatacttca agagccaaac
    20941 gaaaaaaagt catcgataaa ttagcagctg tgatgatctt acaaaattat ttagacggct
    21001 caggtaagca attattttaa taataaaaga aaagaggtaa tcttatgaca gaacataacc
    21061 attcccacga ccatgaagga cacgaacaca tcacattggt ggatgaccaa ggaaatgaaa
    21121 cattatatga aatcctacta acagttgacg gacaagaaga atttggacgt aactatgttc
    21181 ttttatatcc tgctggtgtt tcagaagatg aagatgtaga attacaagct tatgcataca
    21241 tcgaaaacga agatggaaca gaaggcgagt tagaacaaat cgaaacagac gcagaatggg
    21301 acatgattga agaagtattc aatacattca tggcggaaga agaagaatag actataaagc
    21361 taggagaaac cttgatatga tagggtttct ccttttttta ttttttactg tatgccatat
    21421 tgtatgccat ctagtcaata tttaagtgtt gtactaattt ttcaacagtc ttttctttcg
    21481 tttcttttgc caagtgaccg taacaatcga tcgtctgact aatttttgta tgccgtaatc
    21541 tagtttgaac ttctaccata gtagctccag cgtccaagag cattgaagca tgagtgtgtc
    21601 ttgctacatg cacaccgaga aatggaacca tagctttttc acaaatagta atcaatcttg
    21661 cataaatagc gtggtgtgtg attagttctt tatagatacc acaaaaaatc atagtcggat
    21721 cagttacacc aagtgtcagc atatatttcc gctgattaat ctgccatttt tttaatatag
    21781 aaattgttct ttcatctagt ggaagaaccc cagcactaca atcagtttta ggatcactga
    21841 ttttatagcc atttttggat tggcttagtg ttttattgat ggtgaccgta ttttcttgaa
    21901 aatcaatgtc tgaccaattc aatgcaaggg cttcactgat cctaaccccg ctataaaaga
    21961 gaaagcgtag taacgtttta tcaaagtcgt ttcgataagt ttcaggtttg ctgtttaggt
    22021 aatcaaacaa ggtgatcagt tgttctttac tgtaaacttt gaccttttct ttatgcttag
    22081 tggtggttct tttaggcatt aatacgttgt ctagtggatt agtctcaata atcccaagat
    22141 tgatagcgta gctaaaaata cgcttagaag ttgaatgaag taccttgtat tggtcagtag
    22201 tttcagccca gctatttaca atttgttggg ctttttttac cgtgacttca ttcacacgaa
    22261 gatttccata ttttggaaga atccactttc taaacttgat ttcagttttc atgaaggtgg
    22321 cttctcggac agtggtttta tatgtttcta gccacaagtc ataaacttct ttaaacgttt
    22381 cgttgttcgc ttttttaata ccgtttttat cgtagtccac ttgcaagcgt gacaaggcaa
    22441 gctgggcttc tttttttgtt ttgtaacctc gtctacgaac cttatcaggt ttgccagtca
    22501 ttttgttcat tccaagatag gcttcataga gccaaaattt acctttttta gtttcatatt
    22561 gcttgaatgt tgccataata gttttccctc catagtgtag caagccgtgg gggcggttgg
    22621 aggaggcagt ttattattat tttgaatagt gtttatttag ctcagtaaca agagctgtga
    22681 actcttttag aagatcattt tcataaaatt cttgatactc ttttttctca tctgtatttt
    22741 tttctgaatc attaattaat gagtcatatc gtaaaagcgt atttagaaga gctgcgagat
    22801 aagcaattgg ggtactcccg tcaggaaatt caattcgaga tcctgtttta agatatttta
    22861 ttgcgtttgt taaataaatc ttctgtgaga cagtcaggtt atcttcttcg atgttattga
    22921 tagcattaga aagattagaa tcaattatag agttattttt ttcaatagtt tttttcaatt
    22981 gcttttcaag cacatttcgc ttaatttcgg gcatcatatg catatctctt aatgtataag
    23041 atccgtttaa tagataggta gtggatacat ctaatacctt tgaaagttgt ttaagcctgg
    23101 tgttattggg aagattatag ccattttccc aattactaac ggcaccttta ctggccggtg
    23161 gggataattt acctccaagt tgttccattg agagtccctt ttcaattcta gccagtctaa
    23221 ttctttgtcc tgtctccact gcttcggggt atttttttct agccacattt tcaccaccat
    23281 tcatatattt tctctactat atcacgattt aaatatgtgt gaaacataaa agttcaaaaa
    23341 agtatgttaa aattcttgca aatgaaaagg tatgatggta tattgagttt ataagaggta
    23401 tagaaatgta ttcaagagcc tcttgcattt ttttaaaatc tttgtataga aatgtatgct
    23461 aacgaggggg gataaatatg gaattaaaaa ttgacaaact cacgcttgat gatccagctt
    23521 ttaaaattat tgacgatcga gttgttcaac aagtagagca aactcaagga acgttacttt
    23581 cattattaga aaaaaagtac cagtttccaa aatatatgaa caaggcacaa gctgctaagt
    23641 atatgaacgt ttcatacaat actatgatgc agaaatatgt tcctaacggt ttaaagttga
    23701 ttatagttga tggagtcgta agaatttcac aagatgaatg tgatcgcttt atggaagaat
    23761 accaaaaata aacgcaagcc gtgggggcaa agggattaat aggaggaaat aataatggaa
    23821 tcgacacaaa ataaagcaat cgaaaaagta ttatcaacaa ttcttacaga agacacagcg
    23881 gcagaattag caaacttgga aggcaaagcg ctagaagaaa cgtttgaatg tttgtacgaa
    23941 caaatggact atcaaaaatt gctaccacaa gaaccaacgg taagcggagt attgcgtggc
    24001 ttgaacgatt tagtacaagc agagtttaaa gaacgacttt ctattgaaga gtatcaagaa
    24061 attttgtatc agcaagttga gttgttagcg agcttgctag ggcttgaact ggaggacgtt
    24121 gaatgaaaac tgaaatttgg aacggacaca ttataagatt tgtcgatatt aatgatgaat
    24181 ggtgggcagt ggcgaaagat gttgcggaag cgttaggtct taaacaggtt actagagcca
    24241 ttcactcttt gcctaaagat ggggttacta ctagtaaggt catcgattca ttgggcagaa
    24301 cacaagatgt aaacatcatc aacgaaaaaa aatatttacc gcatggcatt caaaagccgt
    24361 aaaaaagaag ccgaggcatt tcaagactgg attttcgaca tcatcaaaga actacgccag
    24421 tccacaggac ttgaaggctt tcaagtattc cgcatgctag acaaagaaca ccaaaaagaa
    24481 gcaatgacta aattaagcca cgctattact gaaccaaaac cagtagacta cattaaagcg
    24541 aatgtgatag ccaataaagc tgtatcaact atttatggtc attccaaaat ggtaaaaaag
    24601 aaagatatga ctcctgaaat gttggttgat cgtgaaccta ttttagatga gacagtagaa
    24661 ttaatgactg ttaaagaaaa atatgggttg cagttttcag tgagtgagaa aatttataat
    24721 cgttctgctg aattgcagac aacttaggag cattaacatg atcgagaaca aagaaaaagc
    24781 cttatccata acagtcttgg cggacaggat aaaggcaact taattgggat aaaacccgat
    24841 attctttgtt ccgattatac catattaaaa aatcggaggg aaccattatg aaacgaaact
    24901 taattatagg aagcatttta atcggcggaa ttttcggctt attaccatta attgcaaaaa
    24961 tagctatctt tgcaggatta gcgttatatc tcttcactgc ttatgacgag tacgactatc
    25021 aattaagaac tggagggcat aagtagatgt acaaaacaaa actattaaac caactcgata
    25081 gccttgaatt agaggaaatt aatcaaggga tcgctgaact agaaaataat atcgggaaaa
    25141 cctactttgg aaattcattc aatgaaaaac taacagtttt gtatgtactc aaaaaacatg
    25201 cagaacacaa aataatttgt cgagaaatca acgagctaaa aaatcagatt ttaaccgcat
    25261 ggttaaacat tactgatatg caagaagcaa gggtgaaaac atttaataca tgggtaaagt
    25321 atcagaatca attaaaaggt gctgaatttg ttcgggatgg gttgaaatac gaacttgagc
    25381 agttgaagct catggaggtg tctgaatgat ttataccagt attttgaaaa aggaggagag
    25441 gtttattggc aaataattat caagcagcaa cggaattaca aaagtcggga tggtcaattt
    25501 atcccttatc tcctggaact aaaattccaa taaaaggctc tagtggttgg aatgatgcaa
    25561 ctaacgattc taatcaaatt aatgaatggt ggacggaaga tgcaactaga aatattgggt
    25621 taatgcttga agatcatcaa atggtggtag ttgacctaga tcaacattct gaaacacgaa
    25681 acggcgttga gaattataaa aaacttgctt caatgtatga tccatttcct tctacttata
    25741 cggaaatcac accaggtaaa ggaatccatt tcttctttaa aattcctgat ggtgtaatta
    25801 tccaacaaga aacaggtgca tttgctgata tcttcgggcg tgatgataaa ggtaaaagtt
    25861 taagcgggat tgatattatc actaaaggag ttccaatagc gccaactatg attatttcaa
    25921 gaagtgttgg gagagcatat gaacctattg aaaacgtatc tctaaataat attgcaccag
    25981 ctcccgattg gctagtgaac ctactgctaa aaaaaccgca agaaataaag actcaatacc
    26041 gacccgtagc aaaaacaggg acagcaaaaa aattagatat gattgttcaa ggcgctggcg
    26101 aaggtagtag aaacgatcat ttaactaagt tatgcggttg gttactatgg cacggtgtag
    26161 ataatcaaac tttagcagaa ttgatttata cagcaaatgc gtacaatgaa ccaccgctaa
    26221 aagataaaga agtgaatcaa attattcgat cgatgattaa aaaagatttg agggggaaag
    26281 ctcatggctc ataagcataa attagatagt attttagact ttcccgaagc cagcgagcgt
    26341 gaagacaata tcattgaatt gaaaacctgg atgtcacgat taagatgcaa taaagacgat
    26401 cagattaaaa gtaacagtgt tgtgaatgca gaattgattt taaccaatga tagcaattta
    26461 gctggaacaa ttgcttataa cgaatttagc ggatacattc acctattaaa agattctcct
    26521 tggatcaatc gtaccgctgg agaatgggaa gacagttttg aggatgcctt aacggcatat
    26581 attgaagaaa actacaatgt agtttttgat gacaacaaaa tacacaaagc agtagtaaat
    26641 gtggctagaa agaatgtttt caacccagta aaagaacgta tcgaaaaagt taaatgggat
    26701 caacagccta gactggaaac actgtttatt gaccttttag gggtagacga caacctttac
    26761 acacgagaag taacaaaacg ttggatagtc ggatcagtcg cacgtatcta taaaccagga
    26821 ataaagtttg agatcgttcc agttttggat ggaccgcaag ggattggtaa gagtaccgtt
    26881 ccagcattac tttacacgga tgattttttc accgattcat tagattcgct aggtgaaaag
    26941 aaagatgatt atatgcagct tcaaggcaat gtaattattg aacttggaga attatcttca
    27001 atgaacaaaa ctaaaattga acagataaaa aacttcatca gtgccaagat cgataaaatt
    27061 agacctcctt atggtcggaa tgtcatagct tgggcaaggc aatgtgtatt tattggaacg
    27121 tcgaatgatg ggcagtattt gaaagatgat acaggaaacc gccgttttta tcctttgcct
    27181 tgtaagaata agccaaagat gaatccgttt aaaacaaagg atgaatattt tcttcaagtg
    27241 ttagctgaag caaaggtgct ttttgataaa ggacaacgaa tctattttag tcccgatgaa
    27301 gataaagaag tcttagaaat tgcaaaagac tatcaagagg atgccaagat ggagaatcca
    27361 attaaagaag caatcactaa atatttggaa atggaaatcc cgtataaatg ggaagaagct
    27421 ccagcgtggg cgagacgttc ttattatcag aactatcctg acagtaaatg taatgagaaa
    27481 aatttacagc atttctataa tggagctact atgcaacaag agttttattt agttgatagc
    27541 gtactcaccg ctgatatttt ggaagctgtt tttgataaac aagcaaagga tttattgaat
    27601 ggtcgatcag atgcagaaac taaaaagatt gccttgatta ttagcagtat tcctggttgg
    27661 gaacggaagc aactgccaaa aagaaataaa cgacgaggat tttacaataa gtcaaatgcc
    27721 tatgaaaata aaaatcgagc tggaaagtac aaaaagtaac gggtagtaac gggtcagtaa
    27781 cacctagccc gttactagtt tacccttact gccccaaggg atacagcaat ttggtaacgg
    27841 ggtaacacct tatttcctta aaacttttga aatagttagc taatatgctg gggaataatg
    27901 ttactggatt ttacccgtta cctgttacca aaacgctaga acccttgtcc ccgttgggat
    27961 tgagtggtaa cgggtacctg ttacgtaggt gttaccacgt gttacgaatc aaggaggaaa
    28021 gtaaatgctc aatattattt caacaaacaa agcaccgaac tttcaatata cagatgaaat
    28081 ggatcggttt ctaatgaaca cgctggcatt tagtgtggga ttggtaacag aagattattc
    28141 cacatttgat ccagaagtat taaagataat ggaagaagaa cctgattggc tgcaggagtc
    28201 agtagcgtgg tgtcaatcgc tagtagtggg atcattggta gatagtggca actatgatga
    28261 tacaggtgag ctaatggatg aatttaattg tctgcttaac ctatatgatc gagcgagaca
    28321 acgagagctt acatcgaatg aggataattt gtttttaaac atccatgata agttcttggc
    28381 tttgctacta acagatgatg aattgataac taatttattg gaggtagaat aattatgcat
    28441 atggaaagta ttagatactt cgatggtgag aaacacattg agtattcaaa cactcaagaa
    28501 gatgtagact ttattagttt tgaggaagat aaaatcacta aagttaattt taaagacgga
    28561 acgtgcttga agatagtttc gccttatatt gaatacaaat caaaatggga acaagatgat
    28621 tctgacgaac gagatcgctt tggttggtaa tctatggcag ttaaaaaaca atgtaatcat
    28681 gctggatgta aaacattgat tgattatagg cagaagtatt gtgggaagca taaagcaaag
    28741 caaacggcaa ttaagcgtga agaaagaaag caaagcgaag gtaaatattt tcaattctat
    28801 caaagtagaa catggcgaaa ggcttcatac ttgtatcggt taaatcatcc agtatgtgag
    28861 gattgcctag aagaaggctt gataaggaaa gctgatgttg tagatcacaa aattgaacta
    28921 aaagatgatt ggaatagacg gttagatgaa actaattttc gttctttatg ccatgcacac
    28981 cataattcca agacagccaa tgaaagacaa agacgagaaa agagtaccct ttgagttaag
    29041 ggggcatagt gtgaaactta ctgacaatcg atgcctactc attttggtac aaataaccgt
    29101 tgtgaaaagg cataagggta attacaaata acgattacac ttgtaatcac aagtgaaaaa
    29161 gtatataatg aaagtaggag atttattgaa aaatacaatt gttattactg ataaaacagg
    29221 gaaacagcgc accattgagt tacctcattt tggtcaagtg accattcaaa tgcagaacgg
    29281 aaaaatcatt tatatagata aattagataa agaaaaattc tgatcgaaaa acgaaggaat
    29341 gtgagcttaa ttgcttacgt tcctttttct tttgtctgaa aggaggacaa catgggacac
    29401 cctaaaatat tacacgatac aaaaggcaat atatcaagtg aagaaaaagc aatccgtgtg
    29461 gacgctagag aagaattgtt caagcagcaa ccattaataa atatcacgcc ccctgactgg
    29521 atggcagcga gcgctagaag tgaatggaat cgtatcgtac caacattaaa aaaagattat
    29581 ccattgagtg aagcagatta tggttcattg gtagcctatt gtttagcctt tgctcgaatg
    29641 aaaacagccg aagccgagat aagaaaatca ggtacgttta tcacatgcga aaacggagta
    29701 aagaaagcca atccagcggt tcgggttcaa tcacaagcta tgagtgattt gaaaaaacaa
    29761 gccacctcac taggtatgac cttagaatca cgatcaaaac tagctttgaa caaggttaaa
    29821 aatgatgaac ccgaagaccc gttcaaagag ttgatgaatt catgaatgat tacattgaga
    29881 aagtcctatc aggtaagctg attgcaccca agaaaattat ccaagcgtgt gagcgtcata
    29941 taagcgattt ggagcgttct aagtcagata gcttccctta tgtgttcgat gaagaacaag
    30001 ccaccaaagc gattaaattc attgagttgc taccatctac ggacggtaaa gcaatcaaga
    30061 tgttaggatt tcaaaaattc attctaggca gtctttatgg ctggcgtact aaagaaggga
    30121 attacaggcg attcaatcga gcgtttacca gtatgagccg taagaatggg aaaacgtata
    30181 tcgcaagtgg catggctgcc aatgcgttga ttatggaaca agaaccagca gaagcaaggc
    30241 aagtattgtt tgtaagtaac gctttgaaac aagctaaatt gggctatgat atgctgtcta
    30301 attcacttag aaacgtggtc aagtctagta agtttttaag accacaactg aaaattatga
    30361 actctaagat tcagcacttg ccctctaatt cgttcgctat ggcactggct agtgaaacca
    30421 gcacgctaga tgggtttgca ccaacaaccg caattcttga cgagtggcac gaagcaaaaa
    30481 ctcgtaaaac gtacaacgtc attaagtcag gaatgaccca acaaaagaac ggcttattgt
    30541 gtgttattag taccgctggg cttgatttaa acgttcctat gtacgaggaa tacttattgt
    30601 tagatcgtgt gctaaaaggc gaagaacaag ccgacaggta ctttatagcg atatgggaat
    30661 tggacgatcc cgaagaaatt cacgatcaag agaaatggat caaagccaat ccgatttttg
    30721 aaagtgaaga aatcaaaaaa gtaatgattc caaccattca agatgatgtg aaccttgctt
    30781 tgaaacaaaa taaccttaat tctgtattgg tgaaaaactt caatttatgg agacaagcga
    30841 gtgaggacag ctatatgatt gctgaagact ggcaggcaac cgaagtagaa ccacaagata
    30901 ttacaggcaa gcccgtttat atcggagtgg atttatctaa aacagatgat ttaactagcg
    30961 tttcatggat cgtaccgcta gataacggcg aactttattg tgattcacat agctttgtag
    31021 ccaccaaata tgggcttcaa gacaaagaaa agcgcgacgg tttgccttat cgagaactag
    31081 aaaaagctgg tgagtgttcc attactcaat tagaaagtgg aatcgtggac tatgaccaag
    31141 tatttcagtt tattcaagat ttgattcaag aaaatgattt ggaatgtatg gggatttgtt
    31201 atgacccgta taacgctaat tcgcttatca gtaaagctga aaaagccaac tacccaatgt
    31261 tagaagtaag acaaggaacg attactctaa acgttccgac ccgaactttt agagaacaag
    31321 tttatgaagg caacgttatt cacaataaaa atacgattct cacccatgca gtgaacaacg
    31381 ctattttaaa aacggataac aacggcattc agattaataa atcaaagaac agtaacaaaa
    31441 ttgatccaat agctgcatta atcaatgcct atgtgtttgc aatggattac ttcaccacaa
    31501 cggaaggagc gaaagcagac aatgaatttt atacaagtga agaattttct ttctaattac
    31561 attcataccg ttcttttact tcttggattg gtgtgtgtgt tggttgctat caccttacta
    31621 acaaatgtct actatggctt gttagcgctg ggcatagtgc ttattggggt agcggtcatg
    31681 ctaaatacag aacagaaggg aggttaaaag atggcatttt ttaaagcgag acaaaataca
    31741 acgggagatc ctttcctaca acatgtggta tcaatccaat cggatgatta caccaccagc
    31801 tttacaagcg ttcgtgcatt aagaaatagt gatgtgtttg cagccgttcg aattattgct
    31861 agtgatattg cttcaagtcc gattcaattg gtcaaaaaca atatgccaca agctgataat
    31921 gaactggtga agttactaaa cgagaaacct aattcagaaa tggatggttg gcatttaaag
    31981 tttgctttgg cggtcaatat gttgctaaac ggtaatagct ttgcagagat taaacgcaac
    32041 ggtgaaaagg tagaagaaat tcacttatta cctaactcaa gtgtaacggt tactcaatta
    32101 gataatggta cgttgtctta tcagattggt gataaaaaaa gacgtgtgaa gtctagcgat
    32161 attttgcact tcaaatattt cacccaagat ggtttaacag gattaccacc actttatgcg
    32221 ttacgtgatg aactgaaaat tcaacaagct ggcaaccgca cattgcacaa tttctttact
    32281 cgtggtgtca gtgggtcagg tattttgaag gttcataagt cagatttaga cggatcagca
    32341 aagaacgcaa ttcgtgaaaa gtttgaagaa gccaacggtt caagtagtgg agataatgct
    32401 cttagaacga tcattcttga tgaaacaatg gactacaaaa cattagaaat aaacaccgat
    32461 gttttgaagc ttatcaattc caatgattgg aacacaaaac aaattgccaa ggcgtttggt
    32521 gtaccgattg agcgtttagg cgttgaaaat gaacattcta gcaccgttca aagtaatctc
    32581 cagtatatcc aaagtacgct gattcattac tttaatgtgt ttgtgagtga attagatacg
    32641 aaacttgaaa ccaatatccg ctttaattcc gatcagttac tagagactga tcctgaaaca
    32701 aaagtaaaaa atgtattgga tcaggtcaaa gggtcacttc tcacgattaa tgaggggcgg
    32761 tcgaaaatgg ggctaccccc catggatggt ggcgatcgtt tactagcaag tttgaacttt
    32821 acgtatttag atacgttgga gaaatatcaa ttaaaagaac aggaaggagt tacaccagtt
    32881 gaataatgaa gaagaaaagg aaaaacggct gacagaagaa gctgagctaa cagccgattc
    32941 tcccaaagta gagaaagaaa atgaaaaaca accaacagac ggcaaaacta tttcaggcta
    33001 tgcgttgaaa ttcgggcaac cgtcaaaaga tttaggcggc tttgtagaag tgattacacc
    33061 cgaagcatta aaagaggtgg atttatcaaa tgtgttctta ttatatggac acgattattc
    33121 aaagccacta gctagtgtca aagcaggtac gttgaaattg aatgtcgatg atacaggatt
    33181 acattttgaa gcagagctaa ccgacacgac ctattcaaat gatgtgtatg agaatatctc
    33241 aaaaggggtt gttgattcta tgtcctttgg gttcgtgctt ggattagatt cattcgacaa
    33301 aaaagaagat ggcacaattg aacgatcaat agataaaatc aaagcactta atgaaattag
    33361 tgtcgtgacc gttcccgctt atgattcatc aaatgtccaa gtaaataagc gttcttacga
    33421 atcgtttatg agtaacaacc aagcaaaaca aacaaacaat agcttagaat ccacttctaa
    33481 agcacaaaag gagagtaata acatggaaaa aactttaatc gataacgaaa aaacagaatt
    33541 gcgtgggtat gaagaatata tccgttcaca aggcgaagtg cgtgatggag tcactactgt
    33601 aaatgcagcg gcagttgttc ccgaagaagt aatcggtgaa gtctttgatt tgaaacgttc
    33661 aaattataac ttagctcaat atgcaacagt aaaaacagta tcaaatggac aaggtaaata
    33721 tccagtagca actaaccaac aagcagtgtt agcaacaaaa gctgaacttg ctgaaattgg
    33781 tgatattgac gctgaaatgt ttacttcagt tgattataaa gtagaaactc gtgctggtaa
    33841 gattgcctta tcaaatgagg ttgtggaaga ttcagcagtg aatattgtac aagaggtcaa
    33901 agatcagtta gcgaaattgg tagaaaacac tgacaataag catatcatgg atttattaaa
    33961 aacattcact aagaaaacgg ctgctacgtt ggacgatttg aaacaactat acaatgtggc
    34021 attagaccca gcattaaata aaatggtaat tctaaaccaa agcggatatt accacctaga
    34081 tacattgaaa gattcagatg gacgttacat tttacaaccc gatgtgacag cacctagtgg
    34141 taaatcatta ttcggtatgc cagtagtatt gattgcagat acattgtttg ccaatcctaa
    34201 agctggaaca ttccctatga ttatggggga tattgcacaa tctatctttg ttgctcgtag
    34261 aaatcaagta acgactcaat gggaaaaatt cgattactac tcacaaggac ttgcagtgat
    34321 cgttcgcaac gattataaga aaattgatca aaatgcttca gtgtatattg agtttacgcc
    34381 agttgtaaca ccaaaagtat agaaaaatat tgggcggcgg tttatcccac tgcctttttt
    34441 tcattaggag agataaaatg gtaattttgg atagcataaa aaaaagtatg cggatcgatc
    34501 acactattga tgatgacttt attcaacaat tgattgatac agcaggcgaa tatataaaaa
    34561 gtgctattga tagtagcgca acggataaag atatggataa ttatcagcaa tttgatttgg
    34621 cggtgtcatt acttactcaa cattggtatt tgaaccgtca agaagccagc agcgaacgga
    34681 taccagtaac ggtacaagca ttagtacaac aaatgagagg tgcttattat gccaatcatt
    34741 aagaatgtaa atgaattgac tgagagagtc aagtttaaaa agacaaaacg ggtaaaagat
    34801 gaagatgggc agatggtgga tagtgaagaa actgtatttg aatgttgggc taatgtgcgt
    34861 tcacaaatgc taaaagacgt gcttgctagt gtaggtacca ttcttgaagg aacgttgacg
    34921 tttattattc gatacgatca agattatgaa ctaacaaacg atatgaaagt agcttggaaa
    34981 aacaagagtt ataaaattat ttcaatcaat gaaggaacgg cgtttaaaga ttatacaacg
    35041 atcatagcta aacagatttc ttagaatgat tacacttgta aacgttgtgg gtatttagta
    35101 taattaaggt agtaaatgaa gggttagctg cctgaatttt gcaagactta gctagtcgaa
    35161 atctattgtt ggactgaaaa ttgtaggtgt ggttgcaaac atgctggact aagaaagatg
    35221 atagatgatg aacgttcaat tttaatacag gcatgctagg actgattgga tggttttggc
    35281 aagctgattg tgtagaaatc aaagaacacg tctgttgtgg acgtgttttt tttgttataa
    35341 ttcaaaagag gtgatttaat ggacaaagca gagtttacaa atttttattg gaagtattat
    35401 ctacatttag aaaatgagtt tattaatacc acagattttg tgatgctcga tgagaataat
    35461 ttcaaaacat tctctattga atatcaaaaa ctactactag cgattggttc ggagtgtgag
    35521 attattttca aagaactttg cggatttgat agcagtagca ataaaagcat aactgatttt
    35581 aaagctgtta ttaaatctag cgaattaatg tgtttggata atggtgttag ggttatgaat
    35641 tctttaacat tgacttcact aaaacctttt ggagatgggt ggcctgaaga tacaccagat
    35701 tggtggaaaa tatataacag agtaaaacat ggtcgttctt caaattataa ggaagcaaat
    35761 ttggaaaatg tgttgtatgc tttagcaagt ctatatttat tagaggaata tttgcataag
    35821 aaagtaatac tagaaggtga agtagacttt ataagtccag agtcaaatct atttacgtta
    35881 tcttgggaaa gaaaacattc gtcgatgcaa aaagtgacgt ttgaaaaagt ggattcaaat
    35941 tatgtagctc cactcattga ttttaaagaa caagaagaaa tttaaaaacc cccacggctt
    36001 attgaagttt ttgtatgcca tattgtatgc catttggttt aaatcgcttg aaaaatagtg
    36061 atagataact ctaattcatt tagtcataaa cgctgttttg ataaccttta tagttctttg
    36121 atatgggttt ctcattcatg gcggaagaag aagaatagaa caaaagaatg aattaataag
    36181 atataaaaaa agggattgtg acaaacgtct tgtcacaatc cctttttcca aataaacgat
    36241 gttcaatcag ctgcccctcg gcattcgctc gaaaaacggc gaaatatgaa gaactatttt
    36301 gccatttgtt tctctaataa tcaggtcaaa acgttgactt cacagtctct tccttaaacg
    36361 gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat gagaagctgt
    36421 tttttgaaat tgttccttgt gactcggagc tgaacggcag gctcacgacc tctttcttaa
    36481 acggtgttca aaagcttgca tctgcggtaa taagttcaac caaacgaaaa ttatgaggag
    36541 ctatttttgt ttggctgttc ttattacttg atgcaggaca gctttttcac aacctctttt
    36601 cgtttagcac taaatttcct taaaaagtag aaaagctttc gaagcctcgt ttgtttcttt
    36661 tactgtataa taaaagaaaa gagtaacaat cgctaaaaga tataaacaag agaaaggaaa
    36721 tacaagatga ttggtctgat ttattttgtg gtgatcgttc tggcgaacac agttggcgct
    36781 atttccggga tgggtggagg cgtgttgatc aaaccgattc ttgatcttat cggcgcccat
    36841 tctgttgcag ggatttcttt ttactcaaca gttgcggtat tcacgatgtc cattgtttcg
    36901 actgtgcgac aagtatcaag cgggaaatca ctgaattggc agattgtcgg ttgggtatct
    36961 agtggagctg ttgttggagg agtagtcggc aacattgtat tcgaagtttt tttacagtta
    37021 tttgaaaacg agaagcatgt gcagctgatc caaatttttt tgacggtatt gaccttggtt
    37081 tttgcgttct tctacaccaa gcatcatcag ccaaaatttc atttgacgtc atggacttgg
    37141 taccttatat gtgggggggg ttctgggctt tttagctagt tttttaggta ttggtggtgg
    37201 accagtcaat gtttctttgt tgatgctgat gtttgcattg ccaataaaag aagcaacact
    37261 atattctcta tctacgattt tcttttctca actggcaaaa ttggtaacga ttgctttaac
    37321 aagtagcttt atgcgctttg atttatctat gttgttttat gttatccccg ctgctgttat
    37381 tggaggtttg tggggagcaa gatttagcag ggttttgtct ccaaaaaaag tgacctttat
    37441 ttttcaagta attgtcctcg tggttctttt ggtcaattgt tacaatgcct ttgtcatctt
    37501 acaaacatta ggagaatcta gactaacgca agtcaaaatc actgaaacat attgttctaa
    37561 atgaaaaaaa gagtatacta tgataaaaaa attcatttta aaaaatcaga aattggctgg
    37621 tgatttggat gttacgggaa atgcgtttag aagatgcaga agcactacgt gaaatcaatg
    37681 cggatcaatt agggtatgat ataccattaa ccgttacggt gagacaaatg aagaaactgc
    37741 tgaaggagcc agagaaaaat tttttcttgg tttatgaaga tcctacttct aaaaaagcag
    37801 ctggctatgt acaagcggag tcctatgaat cgatttttag cgatccaatg ttcaatatta
    37861 tggcacttgc tgtgtctaaa tatgctgaaa aaagaggcat cggaaaggct ttgatgactg
    37921 gcgtagaaga agaagcgaaa aaacgaggaa taacgacaat aaggcttaat tctgcagaat
    37981 acagagtaga agcacaccaa ttttatgaac acatcggtta tcattccgat aaaatgcaaa
    38041 aaagattttt gaaaatcctg taaatcttta tcaaaaaaat acccgatcac caagccgata
    38101 cttgatgatc aggtattttt gtttttttga ctaagaaagt aattgcatca agaaaccaga
    38161 gatgatcaaa acgatggcac caccaagtcg attgcccatt tgagcaaaag caataagttc
    38221 catccgatta gctgcagata agacggctac atttcctgtt ccgcccatcg agttgttgca
    38281 taagccagca gtaatagttg attcaattgg atataaacca aacaaacgac cgacaaatcc
    38341 tgaaacaact gaaatcgcga taacacttgt cagacataag acaacaaatt gccatgtcaa
    38401 agcagaagct aatacattca gattcagcaa cgcaataccg ataccggcaa gaacagctgc
    38461 tgtcaagttt ttgacaatca agttattgaa catgatagct gcatcttcat aatactctgg
    38521 taataggttg gcgattttac agatgacaac gataataatc ataaatgcgt aagcatggac
    38581 tttaggaaca aaatagttac caatttgtcc taagatgaag aaagtcaatg ataccatcaa
    38641 accaacacct aactgtggaa tggaaggttt cacagttcga ggttttccat cgccaagatc
    38701 gcctttttcc attaatttac cattgccgtt gaattttggc attgattgtc cagcacgagc
    38761 aactaatgct gcaccgatga tagctaagac atttgtcatt gctgtcgcag gaatcaggcg
    38821 ggaaatgata gaagaagcat ccgtacctaa aacatttgca taaatcgttg ataaaggaac
    38881 ggctccggct ccaacaccac cagccatcgc aggtaatgag atgtataaaa cggaatttgc
    38941 aaaaccattt ccgataagca tgcccacgag tcctacggca aaaaaggaga cgaccattga
    39001 aataagtgca acgggaataa aacgaacaga agctttcatc aatagattac ggttcatacc
    39061 aaggatgcta ccagtaatca aggcagcaat ataaaagtcc caaaagccca tattgctgac
    39121 aaagttttct gtggatttca ctacatattc aggtaagatc ccaaatgtag caatcgcagc
    39181 agaagcgaag atcgcaaaaa cggaaccacc acccaaataa cttttgacga tagggatttt
    39241 tgtcccgata aaatgaaata aattaccgaa aataaccaaa actgcgattg gtccaatcat
    39301 attcgtcggt aatttcccta aagccattgc aatgatcagg acaaggacca tgatcaaata
    39361 aagtggcaaa cttacgccgg tgatttttgt ggaccaaaaa ccttcttttt tcttttcctc
    39421 aactgcagtt gcagttgttg ttttttgtgc catttttaca gatcctttct tattctgtat
    39481 catatgaaaa aagccaaaga aaagcgacaa aagagcagga gttggctggc cgctgttttg
    39541 ccgcagtcgc ttttttcttt ttagacgtca tacaaagttt ctgtatgttc ttttactata
    39601 acgatcttaa tcttctaaag atttatattc aggaacccat ttagcagatt caactgcttc
    39661 tttgatatcc gtgatttctt cacgattcaa gttttgtgcg acaactgatt ttgcgacagt
    39721 ttcagcaatc gtttgagaaa attcagtgat ttttgctact ggaggcaaga tagctgctcc
    39781 tggttttgtt acatcaacga ttccgcctaa tgctcgacta gcttgagaaa tgatttcagc
    39841 atttactcgt gtagctgttg aagcaatcaa accaagtcct aaacctgggt acatcaaagc
    39901 attatttgct tgaccgattt ggtaagttac accattatat tcaacatcag cagcagggat
    39961 acctgttcca actaatgctt ttccgtccgt ccattctatt aaatcttttg cttttgcttc
    40021 tgccaatttt gttggattag acaaaggcat gatgatcgga cgtggtgtat gagcagccat
    40081 ttctttcacg atttcttcag tgaatgctcc aggttgggta gaagtaccaa tcatgattgt
    40141 cggatggatc gcttttacaa ctgcttctaa gtttgtcaat tcatcagcat tagtgaaatc
    40201 tgagcgtttg cgagcgaatg ggatttgacc aggagtcaat ccttctgtat cttcaaacaa
    40261 taaaccttgt ttatctactt gatagaaatg ttggcgtgct tcttcttcag gtacaccttg
    40321 acggatcatc tcatctaaaa ggatgtttgc gatacccaca ccagcagtac cagcaccaaa
    40381 tgtcaaaatt atttgatctt tcaattgttc accggatata ttcaatccgc ctaatacacc
    40441 tgctaggaca acaattcctg taccttggat atcgtcgttg aaagtagtga tttgatcttc
    40501 gtatttttct aagatcgctg cagcatttcc tcgtccaaaa tcttcccaat gcaataacaa
    40561 ttctgggaat aattcggtag ctgattgaac gaattgatcg atgaattcat agtaagtttc
    40621 gccttctaca cgagcatgac gattgcctaa gtataaggga ttattcaata attcttcatt
    40681 attagtacca gcgtcgatcg atacaggcaa aacttgtgct ggattaatac cagcagcagc
    40741 agtatagacc atcaatttgc cgatagcgat gtcaacaccg ttcacacccc agtcgcccat
    40801 acctaagatt ccttctgcat cagtcacaac aatcaaacga atgtctcgtc catctgccgc
    40861 gttcttcaaa cttgctttga tgttttctgg ttcgtcgatt gaaagaaatg cagcatcttg
    40921 cggtttcaag aaaatttcgt tgtattgttc gattgaatcc gcaacgacag gatcataaac
    40981 gacaggcatg aattcaacta aatgttcgcc catcaattta taaaacaatg tccgattcgt
    41041 attgaataga ttcattaaga agatacgttt ttccaaatct gtttgtttgc ttaagtattg
    41101 accataagct tgaacagatt gttgttccag tgtttggaca gtacttggaa gcataccagt
    41161 gattccatat tttgcccgtt cttcttttgt aaaagctgtt cctttattta gaaaaggatt
    41221 atttaataag tttaaccctg taagcatgaa tgattcctcc taagttttaa tacaaacgaa
    41281 gtatagaagt cagatgatga tatagtcaaa aagagcaggt atgataaatt ttatttatat
    41341 gtaatatagc caaaagaaat caaaatagca gtatttgttc tttttatatc gacaatcctt
    41401 gcttgaatac tatgcgtatc tcttatatgc tagagaaaga aaagtagaag aataagggat
    41461 agatggaatg gataaatagg atttctgagg aaaaaagcac atgatagcgt tgataggagt
    41521 cacctatgtc aggtgataaa aatacataag tagaaaatta agaggaggaa gagaaaatga
    41581 aagaagttca attgattaga aaaagcgaac tatcagaagg cggttgcaat gcatgtggcg
    41641 tagtagaagc gacaagctat acattaaaat tagattccaa tcaagcaata atctctgaac
    41701 tgacagtagg cggtcttgtg gacagtctgg cgcttgctga aggttttact ggagaagata
    41761 tttatgagat gttttcagaa gtccgtcagt taaaaaaagg agaaaaatgc atagaggttc
    41821 atcatgagag cccgaatgtg aggttcaaac gtggtgataa tgagatgatc ttcaagaatc
    41881 atgtgtctga tcacactgaa ctatatgaaa tcgtgaatca aatactgtct gggatttttg
    41941 aattaggacc ttatgagttc aaggaagaaa acggtaatcc aaaattaaat gaagaatggc
    42001 aagaaacgat tgaaacacaa agaaacaatc cacacttatt tcaatagtct tccacagtat
    42061 ttcgtaaaaa tgttgatgaa aaagaaacac cgtgaatcag aggtcgtgaa aaacctgccc
    42121 tgcatcaagt aataagaaca gccaaacaaa aatagctcct cctatttttc gtttggttgg
    42181 gcttattacc gcagatgcaa gtttttgaac accgtttaag gaagagactg tgaagtcaac
    42241 gttctgacct gagtattaga gagacaaatg gcaaaatagt tcctcatatt ttgccatttt
    42301 ttgagctaat accgagggtc agctgattga acaccgtttt atcgagaggt tgtgaaaaag
    42361 tcgcttagtt tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata
    42421 aatttgactt aataccgaga aaatggcttt tgaacaccgt ttattcaaaa aaagggactt
    42481 tgacactact tttgtcaaag tcccatcggt tttttatcta tttttattac aatcatttct
    42541 tccagagtag tgacatctgg aatggctgaa atgtaaacag attatttgcc tgtatcaatg
    42601 tcgaagagta atataaaaag tgtaaacgct atcatattgt tcatcattca aattttatag
    42661 agagaaggca ttgagatgga aaaaacatat caagcaggta caaatgaagg aatagtagat
    42721 tttatcaata tggaagattt agaaatcgcg gcttcacaag tgattccagc tggtggttat
    42781 ggttacatca gcagtggtgc tggcgactta tttacttatc aagaaaatga acgggcattc
    42841 aatcatcgtt tgattattcc tcatgtatta agagatgtag aattacccga tacaactaca
    42901 cattttgacg aagaaatgct gactgcacca atcatcatgg caccagttgc tgctcatgga
    42961 ttagctcatg tgaaggcgga gaaagcttct gcaaaaggtg tagcagattt tgggacgatc
    43021 tatacagcaa gttcttacgc ttcttgtact ttagaagaga taagagaagc aggcggggag
    43081 aaagcaccgc aatggtttca attttatatg agcaaagata atggaatcaa tttggatatt
    43141 cttgaagtgg ccaagcgtaa tggagcaaaa gcaatcgtat tgacagcgga tgcaacagtt
    43201 ggcggaaacc gtgaaacaga ccgcagaaac gggtttacct tcccgctgcc aatgccgatc
    43261 gttcaggctt atcaatcagg agtaggccaa acgatggatg ctgtatataa atcttccaaa
    43321 caaaaactta gtccaaaaga tgtagaattt atcgctgctc attctgattt gccagtctac
    43381 gtgaaaggtg ttcaatcaga agaagatgtc tatcgatcat tagaatctgg tgctggtgga
    43441 atttgggtat ctaaccatgg tggccgtcaa ttagatgggg ggcctgctgc gtttgattcg
    43501 ttgcaatatg tggcagaagc agtagataaa cgtgtaccaa tcgtgtttga cagcggtgta
    43561 cgacgtggac aacatgtttt caaagcaatc gcatcaggtg ccgatcttgt tgctattggc
    43621 agacccgtta tttatggatt gtctttagga ggaagtacag gagtccatca agtgtttgat
    43681 ttctttaaaa cagaattgga aatggtcatg caattagctg gaacacaaac agtagaagat
    43741 atcaaaaaaa taaaattgcg tgagaatcgt tttatttaag aaataaatga cgaaaaaaat
    43801 aggagtgcgg cagatgatgc cgtactccta tttttatagt tcaaggatgt cactaataga
    43861 ataatttgaa acgaaaaaat aaaattgaaa tattttttca tacttaataa aaaaggaaga
    43921 atattcatgt aaacgatttt attgtttttt tctcttttat acaaaaaggg tcataatttc
    43981 aagtaagcgg atgaattcat gaggattttt tgcatactgt ctctactata cttaggtcac
    44041 taagaaaaag gagtgattta ttatgaaaaa gaacatgatt gggacattat tactttcaac
    44101 acttcttcta ggcggcttgg caacaccagc ttttgctgag ggtcaagcga cttcaaaagg
    44161 agatattacc tttactgaac caacaaatac cgttgagcct cttaacccta ctgatccttc
    44221 aaaaccagta gagccagcag atccggaaaa tccagcaact ggccagacag gttctttaac
    44281 attggatgta gttcctgaat tgccatttgg tacacacgag attgaaagcg gaacaaaaac
    44341 gtatcaagta gacgcttcaa aaaacgatac accttatctc caagtatcag atcgtcgagg
    44401 tgtaggtgca gatggccaag cacaagggtg gaacgtgaca gtttcggttt cagattttgt
    44461 aaacggttca caagttttgc aaggcgctga attagatttt ggaacatcca ctgttaaaag
    44521 tacgtcagat aacgaatcca ctggaccaac tagtcaaact gtaactgggt tgagtaaagc
    44581 aagtgcagcg acaccaatat ttacagcagc aaaagatcaa ggtctgggaa catggctttc
    44641 tgtttatgat ccagcaaata tcacactgaa agtgccgaaa gcagcagctg gaacattcac
    44701 ggctgatttg acttggaacc tcgtggctgg cccagtagca tagagtatga aataaattca
    44761 acaaactgcg gtgaaaatac tataggtgaa ggatttttta ccgcagttgt tgttgaaagg
    44821 atgtggtgga caatgaatca aagtaaacga ctgtttgttt cgtttttttc tattttaagt
    44881 ctatttttca tttttccgtc aatcagccaa gcaaaggatt cagcaggaga ctttggaatc
    44941 aaaccggtat ttccagagaa ccaaatagat aaagcaatcg gttattttga tttattagtg
    45001 gcaccggaac aaaatcagac actagaagta attatcagca attcttcaga tgaagaacga
    45061 acatttgagg tctctgtcaa tccggcggta acgagtgatg gtggaacgat cgattatagt
    45121 caaaaaaacc caacgttaga tgagacattg ccgtttgatg tccgtgacgt tttgctcatt
    45181 gcgaaaaagg aaatcaatgt atcagcacat gcagaaacaa ctatacctat agaagtgaaa
    45241 atcccagcaa aaagctttaa gggacgtgta ttagcgggta ttcatgtttc acctaaagaa
    45301 gaagctgaaa cagaaaatgc tacagaagga gcacaaatca aaaatcgtat tgcttataat
    45361 ctcgcagtcg ttttacaaga aagtcaagag acgatagaac cggatctgaa acttttatca
    45421 ggagatttgg acgaggtcaa cgcaaagcca actgttcagc ttcgtttcca aaatcctcag
    45481 cctaggatta tcagcaattt gatatttacg agcaagatct tttatgaaaa tcagctttat
    45541 attgaaaata cgtctaatga atttttagtt gcaccaaatt cgaattttca cttgaatctt
    45601 gatttagctg gtgataaagc aaaagccggc gattaccgcg cagaaatcat agcaaaatca
    45661 ggcgacagta atgaatggcg atttacacaa aactttacga tcaaaaaaga aaaagcacaa
    45721 aaagtaaatg aaaattccgt ttttgcagta caagaacaat ctttcccatg gctttatgca
    45781 ggattggttg ctgcagttct agtgttatgg ttgattttgc tgtttttgtg ggtccacaag
    45841 aaaaagaaaa aaggagaaac aacatgatga ggtgatttcg ttgaaaacat cgatcttatt
    45901 gggagggatt attgcaagtt tgctgttctt cagctggcaa gagccagtcc aagcagatac
    45961 caaaagttca ggtacgatta cattttatga tctaagtcca gttccgcatc caagtggttc
    46021 agtcaatggc gcatcaaaac agcagacaca gctaccgatt tataaagaat ctaatcaaca
    46081 tggcgtattc ccggagacga atgaagaaaa gatccgtttt ctttatttga tcattggtat
    46141 agaattatgg cttcttgcgt ggttgttgtt atggagaaga aaggaaaagg aggatgaaca
    46201 tgttgctaca aaataaattt tcattttttc gctccttctt ttttacttcg ctttttgttt
    46261 taagtatatt tatcttttca ccttcggcag aagctgttgg agcaacgcct cctgccattt
    46321 cttatgatcc atacacgtat gaaaatatcg tacctccaaa tggtggacgt agtgcagtca
    46381 atggcgggaa gcttgtccaa ctaactgggg ctaaccaatt gcctaaattg actgctactt
    46441 atttgaacga tggttcaaat gatccttgga aaggtggcac ggtccgtttt cattgggaaa
    46501 gccatgtgaa actaacaaat gtacttgatt tggtgaatat cactgcacaa ggatttgcat
    46561 ttgtggcgat catcaatttg ccggaacatg tatcaagcag tgatgtatta aaagcaattg
    46621 actggaacaa cgcctacttg tatattgccg gtgcccccat caaggttact agcggtagtt
    46681 tattatcagc aggaagccat accttgcgtt ttgggatggg gtcgtgggat acaaatactc
    46741 tattggcaga tattattgct attattacgc gaggcgaatt caacgtggac gatatcccgc
    46801 ttcaatttga tgttacagct aatgtcgcga agatgacaga aaacggagat aaatatgata
    46861 cgagtccaaa caaaattttg accaagggta aattacaacc ttctatgtct aaaaaggccg
    46921 ttttttctgt tgatttttat gattcgaata atattatcca agatcgtatg ttcaattcga
    46981 ttttagctcc agctgcaggt agattttatc ctaaattaac tggcggaaac ttgaatccag
    47041 gagcatatgc attttctgca agtgcagaga taaatacgtg gaatagttac atctcaacaa
    47101 gtgattcaac aggaaaatat aatacatttg ctgataccac agaatacgtg gatggaaata
    47161 accagaacct tccaggctct accaatagtc ggacattgac gatggggctg actgaaggac
    47221 gttttgatca gttgccattt agtcgctttg atcgcgtagt caactatttt acaggaaaaa
    47281 acgttacaca aggagcaata ctgactcata ctccagcaag cacaagtgga ttgaatcaga
    47341 cagccaatat cgtgtacagt gggaaagatg cgcaaggcgg attgctttct cctgttgctt
    47401 taaaggtatt ggagcagtac aagctagacg gaacggtttt accaacaaac ttaacagccg
    47461 atagtcagtg gggaaagctc ctttcttctg catcgtacca agtcacggcc aattggtcag
    47521 caactgaact aaaaaagggt tcgatccatt acaggcttta ttcgaaagga acccaaaaat
    47581 tagcgacagg atggacagat caacttttcc aaacgatcca atcaaataac gggggtgtaa
    47641 atacagctac ttctacacta cctgcattgg cttcagggca atattatttt gattatcgct
    47701 tggtggacga tgtacttact aacatgtatc cgtcttttgc gtacaaatgg cagtctgaac
    47761 aagctggaat caccactctt cctcaaataa cagtggctaa ttttccatct gtgagtgcag
    47821 atagtcagct aaaaaacctt agcagacaac ctgagacagg agatcccctg tctgctctat
    47881 caggagatac gattcaagaa aatgtgacat tcacgttaac aaaatctggg gatgcgataa
    47941 ccgacaaaaa aatcacgatc tcacttcctg aaaatactac ttatatcaat ggttccttaa
    48001 aattaaatgg tacaactatc gcagataccg gcattcaaca aggagtttct gtcccagcag
    48061 atctattgag caaaatagga gataccattc atcttactta caactatcaa ttaaatactg
    48121 tagatacttc tgtacaatcc gtcagcatac tgacaaaggc agctgtactt tccagcaata
    48181 ttacattagc agatggtgct aagcttccta acccagttgt ccaaacatct gctaaaacaa
    48241 ttcttgtccc caaacaagaa ttaacattag ttaatgtacc agatgatttt acatttggta
    48301 acgatctccc caaaccgttg aagacaagtt attatgaagc aaaaggcgat ttttcttttg
    48361 atgtgcggga tactcggctt ccaagcacgt ctccttggca actgacaggg acattgactt
    48421 ctttatttaa gaatgatcaa ggtcaagaat taagcggaac aaaattatac ttcaatcatt
    48481 ctggatcaaa acaattgatt cagcaaggtc aaaacacgtt gatttatgag agtgatggaa
    48541 cagctaaagg agaggttctc gttgactttc ccgataccga tggtttactc ttagaggtaa
    48601 atagcagtac gaatgctcaa cctggcgcaa cgtatcaagg catggtcaca tgggaactga
    48661 cagctgggcc aaccagctaa gtgattagaa tttgtatgga tctgtgataa ctgtcacaga
    48721 tcctcttttt caaggatgag aaggaaactt ctgctgttaa aatcagaaat gcttggagga
    48781 gtggacttgg aacttttcag tttgcttgaa aaaaatgaac aacggcaaat caaacttttc
    48841 caacttttat tagaggaaaa aggagagatt tccgttaata acgtacttac ccgcttatca
    48901 gttgatcggg ctaccttgaa agaagatctg ttttatttac aagctaactt ggaaaatatc
    48961 aaacaattgg aaattgttat ccaagaaggg aatattttat taatcagaca tggaaatata
    49021 gcagcagtcg atgtttatta tcattgctac ttgcgctatt ctacaaaata tcagatactt
    49081 ctttatctgt tggaaaatgg ctcatttgat cggcagaaac ttgtcatgga acttaatatc
    49141 agttcggcta ctttgtctcg cagagtgaag gaattaaatg attctttaaa tgagtttcat
    49201 ctgaaaataa aaagcgggcg gctgaccggt ccagaaagtc aaatttgtta tttttatttc
    49261 caattatttt ggtttggacg tccttatctt gaaaacaaaa aagaatacag tgatttatca
    49321 ggaaacactt ttttagatct gctgcaaaaa gagtttagtt ttactattac agaagaagga
    49381 cgattgaaat ttgaaatatg gctttccatt atgaagaagc gaatgcgctg tacgaaaaaa
    49441 tccaaaccag attatagcaa tcttcctgtt ggattgtttc aaacgacaca atttttattg
    49501 gacctccata catttttgac ccgttacttc tttcaatatg cctttccttg gaatcaaaat
    49561 gaaacgttgg ttttttatct tttcatgatc agtaacttta cattagatac acataactcg
    49621 catgtccagg agtttttgat aagcgaaaaa tacaaagacg acgtagtagc tcaattgaat
    49681 cgaacgttta aacaatcgat agaagaatat ttctcttttt atgtttttcc agaagagatt
    49741 tcgcaaaaga ttgcgttgac agtgatgcaa aatcacgctc attttgccta ttttagagga
    49801 tggatgaata tttttggcca agaaggatta aaacagcggt taactgaagt agaagataaa
    49861 caattcctgg ttttatgtga aagattggtc agacaaacat ttgctattgt tgattttact
    49921 gaagtagacg aggaaaatgc ccgctttgaa ttatttgctc gctatgcatc tattttgcgg
    49981 acgctgatca agcagttaga attacgtctg caaattgctt atgatcttcc ttatgaaagg
    50041 ctaatggcgg atatcgtgaa agaaatcatc caggaacaat tgctgaatac gatcaaatat
    50101 gatttagtcg aatacgagaa agaaaagcag tatgatatca ttttgactag ccaattgaaa
    50161 gagtacccgt cacagaagtc cgctaaagtt tttgtattca ctagcaacga atataattat
    50221 gatttcccct atttgaacca atttttaaaa gaatgttatt tagaaaaatt gaatttaagg
    50281 atgaataaaa catgaaaatc gtgatcattg gtgcttccca tgcaggcatc acagctgccc
    50341 taaatctaag aaaacttcaa ccgaaagcag aagttttact gatcgatgaa gatcataaag
    50401 atggactagg ctatgtttca aatggaatca acctttattt aaaaggaaag atacgtagtt
    50461 tagctgaagt tgcccataac atgcggactc ttcaagaaag tggggcaaaa ctgatcaccg
    50521 aatggagagt aactgaactt gatccagaca aacatcagct catcctcgca tccaaagaag
    50581 gaaaaaacga gaccataacc tatgataaat taatcgtagc aacaggttcc tctcctgtca
    50641 ccttgtataa acaaattgaa gctgaaaatg tctacaccta taaaaatcta gtgcaatcta
    50701 agcaagtact tgccgcttta aaagaagcaa aagaagtagt gatcttcggt gctggttata
    50761 ttggattgga attagcagat gctttgagaa ataaaggata cattattcat ctagttgatt
    50821 atatgccgaa tgttttatca agatatttcg ataaggatat gatcaacagt tttcaaaatc
    50881 agctgcaaac taagcaaatc aatttttatc caaatgaatt cttgatcgat tggaaaaaat
    50941 cagaagagaa agtagtatcc gtacaacttc tatctcaagc aataaaggca gatatggtca
    51001 ttttttctgc ccaaactcgt cctaatacga cattgttaaa agaaaaagtg gctttgtatg
    51061 aggatgagac tgtgatagtc aatgaatatc tgcagacaag tgatccggac atctatgcga
    51121 ttggagatat cgtcccagtc agttttgaca aaaataaacg gcatctcttt ttacctttag
    51181 ttactcgagc tgtacatatg gcaagagcag tagcgctaac tttgagtggt cagccaaccg
    51241 cttacgacct cagacaaaag ataacagcag cagtcattat agactacttt ttaggaactg
    51301 tagggctgac agaagatgaa gcgccattct tggaacaaaa taccggttcg tgttcaggag
    51361 aatttgatct atttccacaa tacgatgaag aaaacaaaac agtaaatgca aagctgatct
    51421 accatccgga tacattagaa ataattggcg gacagctgat aagccaagaa ttcttattat
    51481 cagatttgaa cctgcttgcg gatatcgtga aacacaaaac tacgattcca cagctagcag
    51541 ttgaggattt tggatttctg tctgaacaca cctctcgttt tcactacctc aatgagttag
    51601 cttttaaagt actagctaag agagcaaata gcaatagagt agataaaaga ctgtgagaaa
    51661 tatcacggtc ttttattgtg tggggatata ataaatatta atcaatcgag aataaaaaat
    51721 tcatataatg aaatagcgga agaatttttt gagcataata ttcgccaaaa atttatcaag
    51781 tgataaaatt gttgtataaa atgattattt caggaggagg agttaaatgt ttttagcatt
    51841 aaatgaaatt atgcattcaa agttacgtta tgcgttagtt gcaggggtga tgtttttgat
    51901 cgcctacctg gtattttttt tgactgggtt agcttatggc ttagctcaag ataatcgaac
    51961 agcagtcgac aagtgggagg cagattcgat tgtgctttcg aaagatgcaa attcaaatct
    52021 agggatgtcc atgattacta agaagatagc agaagaagtc gaaggtggga aagtggcgta
    52081 tcttgcccag acacctggag tcgtgactag taaagacagt acagaagaag gaaaaatcaa
    52141 tgttagcttc ttcggtatcg ataaaaatca attcatcatg cccaatcttg ttgaaggaaa
    52201 agcttttgat aacgatgatg aggcagtagg cgatattagt ttgaaagaag aatatggtct
    52261 agccgtagga gatacagtta agttatctgg tagtgacaag acgtttaaac taactggctt
    52321 tacggatcat gccaaattca atgtctcacc agttctctat acaaccatca atgcttacca
    52381 agagatccgc ttcgaaaaag aagatacaag tgaaaatgca cggattaacg caatagttgt
    52441 cagaggtaaa atcagtaatt tacctgaaga tttagaacag atcaaaattt ctaaattcat
    52501 caatgaatta cctggatata atgcgcaagt attgactttt ggatttatga tcggattttt
    52561 gatcgttatt gcggctattg tgatcgggat tttcatttat gtactgacga tgcaaaagat
    52621 taatatcttt ggtgtaatga aagcacaagg gatcacagga ggatttattg cgcgttctgt
    52681 agtggcacaa acattcattt tatcatttgt tggtattctt cttggtctat taggaacagt
    52741 gggaacatcc cttgttctac ctgatgcggt tccattccaa agcaattggc tgttttttgg
    52801 cgtcattagc ttgttgatgc tggtagtagc tgtgttaggc gcactatttt ctgttcggac
    52861 aatcgtaaaa atcgatccgt tgaaggcaat tggataagaa ggaggaagag catgaaagca
    52921 atagaattta aagaagtaga aaaaagtttc caagatggcg accaagtagt taaagcattg
    52981 aaagaaacaa ccatgagtat cgataaaggg gaatttgttg caatcatcgg tccttctggt
    53041 tcaggtaaaa gtactttttt gactttggca ggcggattgc agacgcctag cagtggctct
    53101 gtatttatca atgatcaaga attcagtaat caaaaagaaa gtgaacgcgt taaactacgt
    53161 tttaaagaaa ttggctttat tttgcaagct tccaatctgg ttccttttct gacagtaaaa
    53221 aagcagttat tattagtaga taagatcaaa catgaacatc gtcaaaaaga agcaaaagaa
    53281 ttatttgagc agcttggcgt ggataagttg atcaacaagt atccagaaga actatctggt
    53341 ggagaacggc aaagggtcgc aatcgctcgt gcattgtaca atgatccgtc cattattcta
    53401 gcagatgaac caactgctag tttggattca gaaaaggcac gagaagtagt cgatatcttg
    53461 gcaaaagaat caaaagacaa aaataaagca acgatcatgg ttactcacga tacacggctg
    53521 attgacaaat gcgatagaat atttatgatg gaagatggtg tattgaaaga aaaagaataa
    53581 ccaaaaagca ggtggaaaaa tggtccatcg atacaacaaa gatacacagc aaaaaatttt
    53641 gaaagaagcg actgacttgt ttatgtccaa gggatatctc ggcacttcaa caagagagat
    53701 cgcacaaaaa gttgggatca cccaacccaa tctctatcat tatttcggtg ataaagaaaa
    53761 actatatacg gcagttttag aaaaccactt aaaagatgtt ggaaaagctt tgagagaaat
    53821 cgttcaaaca agcgaaacgg gatttcaagt aaccttgaca aaaatggcgc agtttttgat
    53881 tgagacacat ctggtcgatt tgtttctgat gcttcacgat cttgaaagca atctttcaaa
    53941 ggaaacaaga gatcatcttt tctttctatg gaagaaaaat tatcgtgaac cttttgaaga
    54001 aatcttttca gcaaaccaat ctgtgctaag aaatgggatt tcaaaagaaa tcgcagcaag
    54061 gcattttttc ttagtgttag caccttacat cactcggtcg aaaagacctg tggaagaacc
    54121 gctaaatgtg gcgcaattga tcgatttata tttgaatggt gtattaggag aagcgtaaag
    54181 ctgttatata gggagaaaaa tagttaggtg aagaagcaag atatgacgaa gatcgttata
    54241 tcttgttttt tttatatagg tagtttttca taaatacaaa tttgttattc tctcatgatt
    54301 atcagggtat atttttattt attatgtcgg tgttccagga agtgttttaa tttaataacg
    54361 aagaaattaa ttgtttgtag aatgaaggaa actatttatt gggtagatga atcaccacga
    54421 atagtcaaaa ggagatttca ggatatgcca aaaatgaaaa aaatcatttt agcagtaatg
    54481 ttattttcta cggttatatc ttttacagcc ccttttttgc gtacttaagc tgattttaag
    54541 ttttgaccct tagtctggat ctacgaggtg agagtcaaga atgaaaaaaa taattggagc
    54601 ttttgtattt gcaatcatta tcattattat ctgttttcaa atagatgttt ttggtcaaaa
    54661 aaagatagtt ggacaaacgg tcagcagtac gaacagtacg gttacaaaga caaaggaatc
    54721 atttgatgat acagaacaag agacattaat caaaatcgga aaaaatgacc gtacactata
    54781 tacagatgac tcgctaacta ccccacttgc aactataaac ggcggagagc tggcggagtt
    54841 tctttctgaa acaaaaaatg cttatcagat caagacaaat gatggctata ctggatattt
    54901 agccctcgaa gatggaacca aagtcacaaa gaatatacaa acaaaaccgg aagagctatc
    54961 tgatgcagtg attgtattag atcctgggca tggcggaaat gatactgggg cattaagcaa
    55021 tgatgaacaa acagaagaaa aagatataac attaagtaca gccataaaag taaaaaaggc
    55081 gctagaggat gctggagcaa cggtttattt gacccatact acagatgaat tagtacagct
    55141 tggagatata tgcgactaca gtgaagaaaa aaaggcagat gtctttatca gtttacacgc
    55201 agactctacg gaatatgcga atgaagcaac tggaatcacg acatattatt actatggaca
    55261 agaggaaaca ttagcacaga caattgctga ctccttcact gatctgcctc tggattcaag
    55321 aggaatctcc actgggaact atcaagttct tcgagaaaat cttcaacctt ctattttaat
    55381 cgagatgggt tatatgaata atgatagtga tttaaaggaa ttagtaacag acagttatca
    55441 gcagcagatt gctgcaagtt tgacacaagc attgaccact tattttcagt aataaataag
    55501 cccagccaaa caaaaatagc tcctcatatt tttcgtttgg ccgggcttat tatcgcagat
    55561 gcaagctttt gaacaccgtt taaggaagag gttgtgagcc tgccgtttaa ctccgcgtca
    55621 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga ctattgtgac ttgtgaccga
    55681 ggagttggca tgagaacacc gtttattcgg aacaagggac tgtgacatga cttttgtcac
    55741 agttccatta tttttttagc agcttcaaag ctttttctgt attggcaaaa tgaagtttgg
    55801 catatttttc aagcataggc atgccgcctt tctccaatag ttttgccgct acttggtcag
    55861 atttcgttcc agctcctgat ggaagggtga ttccagcttc agctgatgct ttgtgtaact
    55921 cttccaaaaa gctggcacga ctgatgatag aagcagcagc aacagctaaa tgatattgtt
    55981 ctcctttagt aacgaagtac agtttttctt gtaattgatt tttttctaaa cgcgcatatt
    56041 ttttaaaatt tgcttccggc gtaaactgat cgatcaaaat cgcttctggt ttttctggct
    56101 cgattttttt tagcagcaaa tggatcgctt gattgtgcaa agcgactttc atccgaacgg
    56161 cattgtattt tggttggatc tcattgtatt tttctggaga taagacaagc agtttatagg
    56221 ggatggtttt ttttaagatg tcagcaagct ggatgatttg gctatctttt aactcttttg
    56281 aatctctaac accaagttta cgtaattctg caagctgatc acgtttcaca taagcagcac
    56341 atactgttag cggaccaaaa tagctgccat ttccgacctc atcactacct aaaacggata
    56401 attgactgat attttttggc aaagaagagg ctgtttttgc tggcttggct tgtttatcct
    56461 gtgcctcccc ccatttatca gcttctattg ctgcattcgt accttgaaac atcacttttc
    56521 cggatgtata agcggtaatg gtcgtcccgt ctttttttgc agcaaagcta gtataaggaa
    56581 tctgtttatt taacaaataa gagcgatagt atgctttcat ttgactaagt tggtcgtttg
    56641 ttgctttgat aatgacgttg ctcataaaat tctcctcgtt tttatacata aaactatacc
    56701 gcaactcacg acttttcgtt ttctaagaga ttgcgagaca tagcattttt ttaaagttta
    56761 tcatataata gttaagtatg tgaaaaatat ttgtggagaa cggtgaaaga accaacttca
    56821 tggtacacta aataaaactt tcatcaaata ggaggaaatg attcgtatgg cgcacgaaaa
    56881 aacacgctac aaagcagtga ttgccaacca aacatatact attatcggac gggaaaccaa
    56941 gcatcatatg gatatcgtaa cgaagctgat caatgaacag ttagcagaat tgaaacaatt
    57001 atcaccacaa atggataatg aacaagcagc aatcttgatg gctgtcaatg cgctttcgga
    57061 tcaattgaag aaacaagaaa gaatcttgga gctggaagaa gaaacagcag aattaaagaa
    57121 aaaaatgatc aaatttacag agcttgaaaa tcgtgtgaaa cgcattgaag caatcgagaa
    57181 cgaagctcgg gaagtattga aagaaaatgg tcaagcagat cataccatta aaaatcatgt
    57241 ggaagcacaa cagattttaa acgagaaacg aaaaggacaa attaaacaaa aatcttctaa
    57301 ttaagatcct tttatcaaaa taagaaaaat ttaaaaaagt tagaagagaa aggaacgtag
    57361 catgctgagt ttgctgattt tatttttatt gctaattgcg tttttttctg gagcacgtcg
    57421 cgggtttgct ttgcaaatca tattcgcgat tggatatgta ttgtcattta ttgctgccca
    57481 gcatttttac aaaccattag caagtcattt ggaattatac attccatacc cagctgtcac
    57541 cccaacatca aagttagcat tttttgatca ggtatttgct tttcacctag atgaagcttt
    57601 ttatgcagga actgcttttc tgattatttt gctaattggc tggctgctta cccgatttgt
    57661 gggggttttt gtccatggat tgacgtatgt gccgatcttg agacaggtag actggattgc
    57721 aggaggcatc ctgtcactaa tcatggctta cgttactata tttttgattt tgcagttact
    57781 tgcctttgtt ccattagtgt ggtccaaaat caattcggcg agcatagttt cgctcgtttt
    57841 atcgttgaga gaacgccatt tcttaccaac aagatgtatg agctttgggt aacgaatatt
    57901 ttgaattaag gaaaatagtg ctggaaaata tttcgttttt tgtacagagt agtttattta
    57961 agaaggctgc gtagcgtatg tccggcacag ctcttttttc atagtgaaag ataaggtgat
    58021 aaaatgaata accgaatcct tgaaacattg gaatttgaaa aagtcaaaca gatggtcaga
    58081 caatttgtag tgactgcaca aggaaaagaa gaactggcag aattggtacc agtgagtgag
    58141 aaacaaacga tcacaaactg gcttcaagaa actgaggatg gattgaaagt gcaacgtctg
    58201 cgaggcggga tccctatacc taaacttgaa aatatccgtc cccatatgaa acggatcgag
    58261 atcggagcag acttgaatgg agtggagctt gcacaagttt ccagagtatt gtctacgaca
    58321 agcgaattga atcgtttcat tgatgatctt tctgacagtg aaatcgaatt tgcacgtttg
    58381 tatatgtggg cagatcagtt agtcacgatc cctgttttga gccgccgttt aaaggaagca
    58441 atcgatgaag acggacgcgt gactgatgac gcttctcctg agttaaagag cataagacag
    58501 aacattcggc gaagtgaaca agctgttcgt gaacagttag atgggatcgt ccgtgggaaa
    58561 aatgcaaagt atttaagtga tgcgatcatc accatgcgaa atgaccgcta cgttatccca
    58621 gtcaaacaag aataccgcgg tgtatttggc ggtgtagtcc acgatcaaag tgcttcagga
    58681 cagactttat ttattgaacc aaaacaagtg gtggatttga ataatcgttt gcgtcaatac
    58741 caaatcgctg aacgaaatga gattcaacgt attttaagtg aactttctgc tgaacttgtt
    58801 ccccatcgtc aagaaatcat ccacaatgct tatgtgattg gtaaaatgga tctgatgaat
    58861 gcaaaagcac gatttggtaa agaagtaaaa gccatcgtgc cgggaatcag tgaagacaat
    58921 catgtcgtct tgaaacaagc aagacatcca ctgatcgatc aggaaaaagt agtttctaat
    58981 gacatcacaa tcggaaaaga ctatcaagcc atcgtcatta caggacctaa cacaggtggg
    59041 aaaacgatca cgttgaagac tttaggtctg ttacaactga tggggcaagc aggattaccg
    59101 attcctgcag gtgaagaaag tcaaatcggt atttttgagg aagtatttgc ggatatagga
    59161 gacgaacagt cgattgagca aagtctatcg accttttctt ctcatatgac gaacactgta
    59221 gatattttat caaaagtcaa tgaaaaaagt ctggtattat ttgacgagct cggtgcagga
    59281 acagatccgc aagaaggtgc tgctctagca atcgcaatct tagatgatct tggtaaaaag
    59341 tctgcttatg tgatggcaac aacgcattat cctgaattga aagtttatgg atacaatcgg
    59401 gcaaatacga ttaatgccag catggagttc gatgtggata cactaagtcc aacgtatcgt
    59461 ttgctgattg gcgttcctgg acgaagcaat gcgtttgaaa tctctagccg attaggtctt
    59521 gatacagaag ttattgatga agcgaagcag ttgatgaatg atgagagcca agatttaaac
    59581 gaaatgatca cagatttaga gaatcgccgg aaaatggcag agaccgaata tctggaaatg
    59641 cgtcattttg tttctgaggc acaagaactt cacgatgatt tgaaagaagc ttacagctat
    59701 ttctttgaag aacgtgaaaa agaaatggaa aaagcaaaga aaaaagcaaa cgaagtcgtg
    59761 tcagaggcgg aagaaaaagc agaaaaaatc attgctgata ttcgtaaaat gcaacagcag
    59821 attgggcaag gaaatgtgaa agagcatcag ttgatcgatg caaagaccca attagcaaat
    59881 ctacatcaag aagaaacttt gaagaaaaat aaagtattga agaaggcgaa agaacaaaaa
    59941 acgttgaaac cgggagacga agtgttggtt acgacttacg gccaaagagg gacgctttta
    60001 cgtaaaaacg ggaatcagtg gcaagtagaa atcggtatat taaaaatgaa tgtgtccgaa
    60061 gacgagctga cgcctgttgc tcctcaaaaa gagccgacac aacgagttat ccatgctgta
    60121 cgatctgaat ctagtagtca cgtgccgaat caattggacc ttcgaggaaa acgatacgaa
    60181 gaagcgctaa gtgaggtaga tcaatatttg gattctgcca ttctagctgg ttatcctcaa
    60241 gtgactattg tccacggaaa aggaacaggc gcacttcgca agggaattac tgattatctt
    60301 aaaaaccatc ggagcgtcaa aagctttgag tttgcaccgg caaaccaagg cggaaatggt
    60361 gcgacaattg ttaaatttaa gtaaagctta ctaaaggtaa gcagatggtt cgctatccaa
    60421 gtatagaaat gctatactaa tcatagattt taaaaatgga ggtctttgat atgtcacaag
    60481 taattacaga taagacattt aatgaagaaa cagataaagg acttgtattg attgattttt
    60541 gggcaacttg gtgtggtcca tgtcgtatgc aagcaccgat tttggatcag ttggaacaag
    60601 aatatgatga agaagaattc agaattgcta aaatggatgt ggatgaaaat ccagaaactc
    60661 ctcaacaatt cggtatcatg agcattccaa cattaatgtt gaaaaaagat ggtcaagtag
    60721 tagaaaaagc tgttggtgtt cattcaaaag aacaactacg tcaaatgatc gatcaatatt
    60781 tataaaaact tacagcaaaa ataagctgag ggtgggactg aatccagttc cgtcctcggt
    60841 ttttttgcgg ttgagttaag gttattcaaa ttaatatttt ttgagtataa ttacgttgtc
    60901 aggctggatt gtttttttga cagacatgct ataataactt taattgaata tgaaggggag
    60961 taccagatga acgaacgaat caaaaacaaa ttagctttac ttcctgatca gcccggctgt
    61021 tacttgatga aagataaaaa tggaacgatc atttatgtcg gcaaagccaa aatattaaaa
    61081 aatcgtgtcc gctcatattt tactggcagc cataatacga aaacggaacg gcttgttagt
    61141 gaaatcgaag actttgaata catcgttaca gaatcgaata tcgaagcatt gctcttagag
    61201 atcaatctga taaagaaaaa tgatcctaaa tacaacatta tgttaaagga tgataaaacc
    61261 tatcctttcc ttaagataac gaatgaaaaa tatccccgtt tggtgattac tcgtaaagta
    61321 ctaaaagaca aagcactgta ttttggacca tatcccgatg tcggtgcggc gaatgagaca
    61381 aagaagatcc tcgatcgatt atttcctctg agaaaatgca aacctagtca gacgaaggag
    61441 ccttgtcttt actatcattt gggacaatgt ctgtgtcctt attatttcga cgtagatccg
    61501 aaagtctata cgaaaatcgt tgatgaagtg aaaaagtttt taaacggagg acacgaaaaa
    61561 atcgagtcag agatccatca gaaaatggaa aaagctgctg aaaacatgga gtttgaaaaa
    61621 gctgcagaat accgagacca gatccgtgcc attgagacaa tcatgactcg ccaaaaaatg
    61681 acaaatactg atttactgga tcgagatgta tttggttatg cgattgacaa aggatggatg
    61741 tgtgtccaag tgtttttcgt aagacaagga aagctaattg aacgagatgt ttcaatgttt
    61801 cctttctata acgaagcaga agaagatttc ttgacttacc tcggtcagtt ttatcaggaa
    61861 aatgagcatt tcattcctaa agaagtcttg attcctgata cgatcgacaa gcccagtgta
    61921 gaagctttgt tagctacgaa agtgctgcaa ccaaaacgag gagaaaagaa aaaattagtt
    61981 gaattggcga ataagaatgc ctcagttgct ttgaatgaac ggtttgatct gattgccaga
    62041 aaacaggaac ggacgatcgg agcagttgaa cgtttaggaa acgcgatgaa tatcccgacc
    62101 ccaatacgta tcgagtcttt tgataactct aatatcatgg ggacgaatcc tgtggctgcg
    62161 atggtcgtat tcattgatgg aaaaccggca agaaaagaat atcggaaata taaaataaaa
    62221 acagtcaacg gaccggatga ttatgcatca atgagagaag tcatctatcg cagatattca
    62281 cgagtgattc gcgaagggtt gcctttacct gatttgatct tgatcgatgg aggaaaagga
    62341 caagtagatg tggcaaaaga tgtcttagaa aatcaattag gaatcgatat tcctattgct
    62401 ggcatggcaa aaaacgataa acataaaaca aatgagttgc tattcggtat agatttggct
    62461 gtagtaccgc ttgagcgaaa ttcaccagag tttttcttac tccagcgaat ccaagatgaa
    62521 gtccatcgat tcgcaatcac tttccatcgg cagctacgca gtaaaaacag ttttgcttcc
    62581 cgattagatg aaattgaagg gttaggacca aaacgaaaaa aaatgctgct taaagagttc
    62641 aaatcgttga aaaatatcac agcagccacg acagaagaat tacaagaaat cggactgccg
    62701 aaaaatgtcg cacaaaacgt atttgataaa ttacatcagg aatgaggaaa gggcacttta
    62761 caaagaaagt aaagtgtcct atcattttat gtacaacaaa aagagcgttt acgttttgtt
    62821 ggtaaataat aaatcgctta cgtctggtgt ctaaggatat atgtgatttc ttgaagaagg
    62881 agtgaagaaa tgttagaagt caaggatctt gttaaaactt ttgggaacta cacagctgtc
    62941 gatcatgtct ctttccaaat ccccgatgga aaaatcatgg ggctaattgg ccaaaacggg
    63001 gctgggaaga caacgacttt tcgtttgatc ttggattttt tgacacaaga ccaaggagaa
    63061 gtgttatgga atggccatca tcttggggag aaagattatg atgtcatcgg ttatcttccg
    63121 gaggaacggg gactttatcc gaaagtaacg attcaagacc aactgcttta ttttgcagaa
    63181 cttagaggga aatcaagaaa agagattgaa ccaaaaatcg atttttggat ggaaaaattt
    63241 caggtaaaag ggaaaaagac ggataaagta aaatctttgt ctaaaggaaa tcagcaaaaa
    63301 gtccagctga tcgccacgtt aatccatgaa cctaaattga tcattttgga tgagccattc
    63361 agcgggttag atccggtaaa tgctgaattg ctaaaagatg gaatattgga attgaaaaaa
    63421 catggttcat gtgtcatttt ttctagccac aatatggata atgtagaaaa aatctgcgat
    63481 catttgatca tgttgcgaaa cggaaaaatg gttttgaatg gaaaagtaca tgagattcgt
    63541 gaatcatttg gccgtacgaa gttattcttg gaatctggtt taagccaaca ggaagtagaa
    63601 gaaatcgaag gcgtgaaaaa agtgatcctt catgaagaca atacgttaga gattacctta
    63661 gaagatcctg aagctgggaa agaaatcttt actcgtgcga ctcagttcgg ctacattcct
    63721 atgtttaacc agcaaccgcc aactttggaa gagattttca aattgaaagc aggtgaaatc
    63781 gatgcgtaag ttttggatta ttaccaaaga tgtctattta aaaaatgtta agtcgatttc
    63841 tttcttgatc atgatattag tcccttttat catgctgggt atcatttatg tagcaggaaa
    63901 ctttgctcaa caaaatagtg atgtcaataa aatcggcgta ttggctgata atgagcaaat
    63961 cagtcagcaa atgagccaag tcaaaacaga tgattttgag ttcaaagcag ttgattctga
    64021 agaaaaagca caaaaagagc tttcggaaga aaaaatcgat gcgtatttag tagtctcaac
    64081 tgagaatgat aagataaatg ggatgcttta tagcgaaaat tcattaggac aaagtacaca
    64141 actactgata caacaacaac tgactggctt gcaatcgatg cttcgagcaa gtcaattagg
    64201 catttcacca gaagaagtag ctagcttgag ccaacaagca agtttgactc gacaaaaagt
    64261 caattttgat tcaaaaggaa aaatgacagt tggagaagat aactcgacag tccaatatgt
    64321 cgtaagttat gtagcaacga ttgtcttgtt cattattatt ttgacgtatg cgcagatcat
    64381 tgcacaagag atcgcttctg aaaaaggcac gcggatcatg gaagtgatcc tgtccagtac
    64441 gactgcacaa aagcattttt acggaaaact aacaggtgtt ttacttgttg cattaacgca
    64501 aatggcatta tacggtatta tttttggtat aggatacagt caattcaaag atatggaaat
    64561 ggtcaaaaat atattagacg gtatctcatt ggataacttg attggaccat tcttgtggta
    64621 ttctcttcta ttcatgatct ttggcatttt gattttttct gttttagcag ctttatgtgg
    64681 ctctttggtc aacaaagcag aagatacagc aaaagcaatt ttgccagtga cttatctatc
    64741 tctaggcgga tatatgcttg gattgatact aggagcttca gatccaaaca atatcgttat
    64801 tcggatcact tcgtatattc cattcttatc ttcatatatt atgccggttc gcttagcaaa
    64861 tgagacagtc ggtatgggtg gagcattgat ttccttgttg gtacttgtag ccgtaacatt
    64921 cttattgatg atcttgtctg caaacatgta caaatcgaat gtactcgtgt atagcgaagg
    64981 cggattatgg agttcattga aacaatcgat ttcaattatg agaaatgaac gaaaaaaagc
    65041 ataaaatata gaaaaatata gaaggaagct ggacatttat tgttcccagc ttcttttttg
    65101 tatagaccta tttctatttt tttattatat tggatatata tattcattga aaatagagca
    65161 taacaacttt ataatgttga gtataccaat ttttggaggc gttttaatgg accgctattt
    65221 agatttactt tcagagaagt tccctacaac ggaagatgtc atcacggaaa tcatcaatct
    65281 cgaagcaatt ttgcagcttc caaaaggaac agagttattt ttgagcgata tacatggcga
    65341 atttcctgct tttgatcata ttctgcgtat cggttcagga aatcttaaag aaaagatcaa
    65401 agaccttttc tctgaacaaa tgacggaaac ggagatcagc caattcacta tttttacggc
    65461 ttatccagaa tatgtgttga cgactgattg gtacaaaaaa caagataaat cccagctgat
    65521 ccatcgtttg atcgatcttt tacggtttac gacagtcaaa tacactcgat caaaagttcg
    65581 aaaaggattg ccgaaagaat atagctatat cattgaggaa ctcttgtata tcgatgatcg
    65641 tatcaacggg aaaaaagact atgtaaaaaa aatcattgaa caacttgtct tgatgaagga
    65701 agaagaaaaa tttttaacaa aacttgcgca gacgatccaa aaatctgtca tcgatcattt
    65761 gcatatcgtg ggtgatattt ttgatcgagg aactcaagca gccaaagtaa tggatcgaat
    65821 catggatttt tcctctgtag atatccagtg ggggaatcat gatattttgt ggattggtgc
    65881 gtattgcggc tctgaggcat gtttattgac gcttttacgg attgccgcac gctacaacta
    65941 tttatttgaa ttagagaaag aatatggatt aaatttacgt ccattatttt cttttgccca
    66001 tcaaacctat cagaagaatc cagtatttac ccctaaaaac aggaaagatc tatctgaaag
    66061 agagcaagaa gaattagaaa agatccatca agcactttct atcctccaat tcaaatcaga
    66121 acatcagttg ttgaatcgac gacctgaatt taaaatggac gatcgtaaat tgttggaaaa
    66181 aatcaactat gaggaatcaa cgatcgtttt agaaggtcag ctctatgagt tgaaagggac
    66241 ttgttttcaa acgatccagc cagatgatcc taaaaaattc ttggaagagg aacaaaaagt
    66301 gatcgatagt ttgatgtatt cattccagca ctcgttaaga atgcaaaaac acatgacgtt
    66361 tttgatcgaa aaagggggaa tgtatctcac gaacaatcag catgtactgt tccatggctg
    66421 tatacctgta gatgaaaagg ggcagctctt agcatttgaa ttagaccaat cttatcgcgg
    66481 aaaagaactg ctgggatttt ttgaaaaaca gataactgaa agcgcaaaag atttgactgc
    66541 aaatgaagat ttggcgaccg atttgatttg gtatgcgtgg agcgggccat tttcgccttt
    66601 attcggcaag agtaaaatgg caacttttga gcgctatttt ctcacagagc ctcatacgca
    66661 cgtcgaaaaa agcaatccct attatcactt gcgagatgaa gagtggttca gtgaaaaaat
    66721 tttggcagaa ttcgatgcaa aagaagaagg ttcagcaatc atcaatggac acacgccagt
    66781 aaaagtaaaa aaaggagagt caccgatcaa agcaaacgga aaagcatttg ttattgacgg
    66841 aggtctatcc aaagcttatc aaaaaacaac cgggattgct ggctactcat tactatgcaa
    66901 ttcttacggt ttccaaatcg tgacacatta tccgttcttg cctattgaac aacaatttgc
    66961 aaaaaaatct gatcaaacga atgtaaaaaa agtgatcgag cagcagctcc cacgcaaact
    67021 taatcggaat acgacaaaag gaatggaatt acagcaacag attactcaac tccaaaggct
    67081 gttggattat cgaaaggacg attgagaaaa atgctagcca acattgctca atagactaaa
    67141 aagcgactgc aacaaaaggc gtgtcgcagt ctccttcgga attagctcaa aaaacggtaa
    67201 aatattagaa gctatttttc tgtttatttc tctaatactc aggtcagggc gctgatttca
    67261 cgacctcttc cttaaacggt gttctcctgc caactcctcg gtcacaagtc acaatatcca
    67321 acaaacatga gaagctgttt tttgaaattg ctccttgtga ctcagagttg aacggcaggc
    67381 tcacgaccta atcagaaaaa cgattaaaat tcattcacaa agaaatcgaa taaacgctgt
    67441 tcagatgaat ctacacgatg agaaagttcc ggatgccatt ggacaccaag gattttgtgc
    67501 atattatctt tactttggac tgcttcaatg agtccatcgt tggaaaaggc gatggctttt
    67561 aacaaaggag aaagatcttt gactgcctga tgatgatagg aattcacaaa gtatgaatca
    67621 gggagaaggt cacttaataa actgtccgaa acgattttga cttcgtgagt tgcaaactgc
    67681 ggggcagtgg gctgttgttc gtgttttacg gaccattttg gatataatga aagatcttga
    67741 taaagtgttc cctccaacac gacattcaat agttgaagtc ctcggcagac tgcaaaaatc
    67801 ggttttcttt gtttcaatgc ttccaagatc aatgcctgtt cgaattggtc tcgttgaata
    67861 tttgtttccg tcagttttgg atgagggtct tccatgtaaa gttgcggact aacatcctga
    67921 ccgcctgcaa gaatgagttt gtcgattttc tcaattagtt gaggcgctga atctggagac
    67981 atgactggca gaataagagg taatccttga gcatctaaaa ctgcatccac aaatccctgc
    68041 ggtgtatagc ttacttgatt tccttggaaa gtatctgtcg ctcgaatcag ttgattcccg
    68101 gcaatgccga tgattggttt catttttatt ccccctaaag tagactaatt gtaacaagga
    68161 tttaaaaaaa tttaaactat gtaagacttg cccctatact tatctgttct tgctgtgtta
    68221 ctatctgtaa agagaatttt cgtgtgaaat tcatgacgat agttgaaaat attgcttaat
    68281 ttgttataat aaaaagtaag cagaaataaa aaggttgggc gtaagcttca aggatctagt
    68341 tcttcaaggg gtgagaagga cattttattg aaggggcctg cctatactaa gttatcttta
    68401 gaggtacata ctttcaatga aaaaagaaag catgtacctc ttttttaaat cgaaaggaag
    68461 tgaagcaagt gttagaagct ttggaacaaa tccgaaaagc agaagaagaa aatgagaagc
    68521 gtgctcgaac cctacggcag cagttgaaga cctatgcaga agaaaaagag caagaattgg
    68581 agataatcca aacgaacagt cggcaacagc tgaaacagtt ggtagaagaa aaagaacaat
    68641 tcgaaaagca agaattagaa aaagaaaaaa tgaaattgaa agcagaagca gacaaggtgc
    68701 aagcaacttt gaaagaccaa tatcaaaagc atcagagtca agcaatcggt gcaatcattg
    68761 aaagggtgaa agaaacttat ggccgtcact aagatggaaa aagtgaccct catttcagat
    68821 aaaagaaatc aggagaggat tttacaagca gtacaaggaa tccaaaatgt tgaaatccgg
    68881 gatctgtatc aaaatagaac aaacaaccag tgggtagaaa aatattttcc agataccacg
    68941 attattgata aagaagcaaa attaagcgct ttaggcaatc ggctgaaaga catccaagaa
    69001 gctatccaat tcatacaaca ccacggcgat agccgtcaaa agaaactcca tttgaaacgt
    69061 caagaacttt ccttacaaga cttggaagca aattattccg aagaaaattt catgaataaa
    69121 ttagaagaag tccttgattt aaaagaaaag tgggaacagc taactgaaaa acgtgatcgt
    69181 ttagaagaag aggaagaatg gcttcttcat tggcaacagc tggatattgc tccaagtatg
    69241 tatgcaagta agacgaccat ttttgagatg gggactgtga gtgcagcaaa ttttgaaagt
    69301 ttcaaggaag aactaagtaa gcttgatgac gtttatatgg aagaaataga ttatacgcca
    69361 aaacaagttt atctttcgta tgttgcttta aaaaaatcag ttgctgctat agaagaaatt
    69421 gctgggaaat acgggttcaa taaagaaacg tatccttatg aacaaaatcc taaagaaaaa
    69481 ttgcaagaaa ccaaacagca attatccatt gttcacgagc agcaaaaaaa gataacgaca
    69541 gcgttaggtc agtgcagcgg ctatatccaa gaatttgaat gggtagaaga agtcacactt
    69601 gccgttgcag aacgggaaaa agtaaaagaa cggtttatcc atgccactta tctgatcgtt
    69661 ttgcaaggtt gggtagatgc agaagaaaaa cagaatttga tgcatgtgtt aaacgaaact
    69721 gtatcagaag aagatatata cgttagtttc gaaacaccaa actcagaaga gattcagcag
    69781 gaagtcccta ctaaattgaa aaaccatccg cttatcgaac cttttgaatt gctgactgaa
    69841 atgtacagtc tgccaaaata tgaagaagta gatccaacgc cttggatgac accattttat
    69901 cttgtcttct tcgggatgat ggtcgcagat gttggttacg gattgctgat gctcattggg
    69961 acaatactag ctcaaaaact atttgtttta ccccgcggga tgaaacgttt cgtaaaattc
    70021 tttgagattc tctcggtacc atcgatcatc tggggattga tctacagttc atttttcgga
    70081 caggcattac caaaagaact atttggtatc cgcttgcctt tcccaatcct atctacgacg
    70141 gatgacgtca atacgatttt gattttatcc gtgattttcg gtctgataca gatcttggtt
    70201 ggattattcg tggcagcaaa ggaaaatatc aggaggaaag attacttgag tgctgtcagt
    70261 gatggttttg cctggcaagg gatcctgatt gggatcgtta ttgcattgat tggtgtcatg
    70321 ttgataaaaa atacagcatt tgtttatctt ggcgcggggc tatcgatcat tgctgcttta
    70381 tgtatcttaa tcgtgccgat tatccaatcg ccgtctaaag tcaagggtgc tgccaaagga
    70441 gcgtataatc tttacggatt gactggttat atcggtgatt tagtcagtta tacacgtttg
    70501 atggcactag gtatttcagg cggaagtatt ggcgcggcat tcaatatgct agttgctttc
    70561 atgccgccag ccgctcgatt cagtgtaggg atccttttga tcatcgcttt acacgcactg
    70621 aatatgtttt tgacactgtt aagtgcctat gtccatggtg cacgattgca gtatgtcgaa
    70681 ttttttggaa aattttatac aggaggcgga cgtgcctttg acccgctgaa aacggcggaa
    70741 aaatacgtca acatcaatca taagaaaaaa aacaataaat aattggagga tttttataca
    70801 atgatggatt acttaattag tcaaaatggt ggaatggtat ttgcagtatt agcgatggca
    70861 acagcgacga ttttttcagg gattggttca gctaaaggtg ttggaatgac aggtgaggca
    70921 gcagcagcgt taacaacaag tcaacccgaa aaattcggac aggctttgat tctgcaattg
    70981 cttccaggta cgcaagggtt gtatggattc gttatcgcct ttttgatttt tatcaactta
    71041 ggaaatgata tgtcagttgt acaaggattg aactttctag gcgcttctct gccgattgct
    71101 tttacaggtt tgttttcagg tatcgcccaa gggaaagttg cagcagcagg tatccaaatt
    71161 ttagcgaaaa aacctgaaca tgctacaaaa ggaatcattt ttgctgcgat ggttgaaaca
    71221 tatgcgattt taggtttcgt tatttccttc ctattagtat tgaatgccta agcataaagg
    71281 aggaaaagca gatgaacgcc attgaaaaaa tcatctctca gatgaatgaa gcagcagagc
    71341 aagaaagagc ggcgttagag caagaagagc gaatgaagat cgatcaaaac tttgaacaaa
    71401 aacgtacgca aatcgaaaca gaacatcaaa aacaaaaaga aaaacaaatc gaattacttg
    71461 aaaaaaaata ccgtcagctt aggaatcgcc aacaagtaga agtacgacaa gaaaatttga
    71521 atgcgaagca ggaattttta cgacgattgt ttgcagatgc aatagctgaa atggagaatt
    71581 gggatgaatc tgaacaaatc cagtttatca aaaattcatt gtattcatta cctttgacag
    71641 gcaaagtaac attcattgct ggagaaaaat cagcagctta tctttctcag acattgctgg
    71701 atgaatggaa caatgaactt ccctttatga tggttttaag tgatgaaact gttgctgatc
    71761 aagcgggttt tctgataaac gatcaaggag ttcagtataa ttttcttttc agcagccttg
    71821 tacaagatat ccaaggaacg atgagttttg agattgccaa tcaattattc gaataaggag
    71881 ggatcagtgt atggaatacc acgaactaaa tcccttgatt cgcggaagag agcttgaact
    71941 tttgtccaat gagacatttg aacggatgat tcaaacaaat tctgtcgaag cacttggtga
    72001 aatattgaaa tccacgattt acagtccata tatttatgac ggatatgaat atgacttcga
    72061 acagaatctt ttaaaggagc agagccgtct atttcgctgg ttaaaggaat cagcaccgga
    72121 gcctgaaatc gtttggatct atacgatgcg ctatactttc cataatctga aggttttgac
    72181 aaaagccgag atgacaaatc aaaatctgga ccatttgtat atcgacgatg gattttattc
    72241 attagaaacc ttgaaggatg ccattcatac gcaagtttca aatgaactcc ctgaaagcat
    72301 tatggacagt atacgagaag tacgtgatta ttttgaagag tctaccattc ttcagggaat
    72361 tgacgtgatt tatgatcgac agtttttgac agagcagcga cggcttgccg ataagctagg
    72421 atatcaagaa ttgctgacag aagtcattgc ttttattgac ttgaccaata tcacaacgat
    72481 ggctcgagga atattgcaga aaagaacata tgggttcatg acgacggtac tttccagctc
    72541 gggaagtatc gaaaaagaag tatttttgaa ctttgtagat aaagatatgg aagattacac
    72601 gaattttcta ttagagacag attatgctga ttttctgcgc cctgtcatcc gtgagggaaa
    72661 tcttgatctc gtaaagcttg aacagttgaa agatgattat ctaagttcat tgtatcaaga
    72721 agcacaaacc caggctttcg gaccactgcc actactagcc tttttgaacg caaaagaggt
    72781 agaaagcaaa aaccttcgtt tactggttat cggcaaaaga agccatttcg aaccagaaac
    72841 aatcagaaag cgggtgagac aagtctatga cgcataagat cggtgtagtt ggcgacaaag
    72901 attctgtttt gccattcaaa ttgtttggct ttgatgttcg ttatggtaca accaagcaaa
    72961 ccgttcgtca ggcaattgaa gaaatggcaa agaatgagta tggcgtgatt tatgtcacag
    73021 agcaatgtgc agcattgagc ccagaaacga tcgaacgtta caaggaacaa atgatacctg
    73081 ctatcgtatt gattcccaat catcaaggat cattagggat agggctggaa gaaattcaaa
    73141 aaaacgtaga aaaagcagta ggtcaaaata tcttatagta tgaaaaggag atagaaattt
    73201 tgcaaattgg aaaaatcata aaagtctccg gacctcttgt aatggctgag aacatgtctg
    73261 atgccagtat ccaagacatg tgtctagtgg gagatctagg agttatcgga gaaattatcg
    73321 agatgcgtgg cgatgtggcg tctattcaag tatatgaaga gacttctgga attggtccag
    73381 gcgaaccggt tcgctctact ggtgaagctt tatctgttga attaggacca gggatcattt
    73441 cacaaatgtt tgacggaatc caacggccat tagatacctt tatggaaatc acacaaagta
    73501 atttcttagg gcgcggagtt caattgcccg cattggacca tgagaaaaaa tggtggttcg
    73561 aaccaacagt agaagccgga gaaacggtga gtgctggaga tgttatcggg atcgtagaag
    73621 aaacaaaagt tataaaacat aaaatcatgg tgccaaatgg gataaaagga acgatcaaaa
    73681 caatcgaaaa aggttcattc actattgatg aaacagtatg tgtcattgaa accgaaaatg
    73741 gtgacaaaaa tttgacgatg cttcaaaaat ggccagtaag acgtagtcgg ccaatcaaag
    73801 aaaaattaaa cccggatgca cccatgatca ctggacagcg agtgattgat acattcttcc
    73861 cagtgacaaa aggaggagca gcagctgtac ctggtccttt tggtgcaggg aaaacagtcg
    73921 ttcagcatca aattgcaaaa tgggccgatg tggacatggt tgtctatgtg ggatgtggcg
    73981 agcgtggaaa tgagatgacg gatgttttaa atgaattccc tgaattgatt gaccctaata
    74041 caggagaatc gttgatggaa cgtacggtat tgattgctaa tacatcaaac atgccagtag
    74101 cagctcgaga agcttctatc tatacgggaa tcacaattgc ggaatatttc cgtgacatgg
    74161 gttatgacgt tgctatcatg gcagactcca cttcacgatg ggcagaagca cttcgtgaga
    74221 tgagcggacg tttggaagaa atgcctggtg atgaaggtta tccagcttat cttggttcac
    74281 ggcttgcgga atactatgaa cgatctggaa gagtcattgc attaggatca gaaggtcgcg
    74341 aaggaagtat aaccgcaatc agtgctgtat ccccgtctgg aggggatatt tcggaaccag
    74401 tcacacaaaa tacattgcgg gtcgtaaaag tattctgggg tcttgattcc agtttagccc
    74461 aaaaaagaca ttttccttcg atcgattgga tacaaagcta ttctctttat tcaacagaag
    74521 tagggaagta tatggatcat atccttcaag ctgactgggc atccatggtc accgagggca
    74581 tgcgtatttt gcaggaagaa cagcagctga atgaaatcgt gcgtttggta gggattgatt
    74641 ccctttcaga taatgaccgt ctgacattag aagtggcaaa atccattcgt gaagattatt
    74701 tgcagcaaaa tgcttttgat gatgtcgata cattcacttc aagagagaaa caattcaaaa
    74761 tgttgaagat gatcttgacc tttggtgaag aaggacgccg tgcgttgtcg ttaggtgctt
    74821 atttaagtga gatcatggac ggtaccgtat cgattcgtga aaggatcgga cgaagcaaat
    74881 atatcccgga aacagaatta gaaaaactag atcaaattat tggtgaaatc aagcaaacga
    74941 tgcaaacgat cgtttcagaa ggaggcatga gcaatgatta aagaatatcg tacgatcggt
    75001 gaagtcgtcg gtccattgat ggcggttgaa aaagttgctg gtgtcaaata tgaagaatta
    75061 atcgaagtcc gtatgcaaaa tggcgagatt cgtcgtggac aagtattgga agtccaagaa
    75121 gataaagcaa tggtccaaat attcgaagga acaagtggta tcaatttacg tgactcttct
    75181 gtacgatttt taggccatcc tttagaacta ggtgtatcgg aagacatgat cggtcgagta
    75241 ttcgatggtt tgggacgacc gaaagataac ggaccagaga tcctgcctga aaagcatttg
    75301 gatattaacg gagaagtaat caatccagta gctcgggatt atccagatga gtttatccaa
    75361 acaggtatct ctgcaatcga tcatttgaat acattagttc gtgggcaaaa attaccagta
    75421 ttttctggct ctggtcttcc tcataaagaa ttagctgctc agatcgcgcg acaagcaacg
    75481 gtactcgatt catcagatga tttcgccgta gtctttgctg ctattggaat cacttttgaa
    75541 gaagctgaat ttttcatgga agattttcgt caaacgggcg caatcgaccg ttctgtcatg
    75601 tttatgaatt tagcaaacga ccctgcaatc gaacgtatcg ctactcctcg tatggctttg
    75661 actgctgcag aatatcttgc ttatgaaaag ggaatgcatg ttttggttat catgacagac
    75721 atgaccaact atgcagaggc attgcgagag atttctgcag cacggcgaga agttccagga
    75781 agaagaggat atcctgggta tctttacacg aacttagcta ctttattcga acgagcagga
    75841 agaatccgcg gactaaaagg atcggttact caaattccga ttctaacaat gccagaagac
    75901 gataaaactc atccaatccc tgacttgact ggttatatta cagaaggaca gatcatcttg
    75961 actagagagc tttacaagag tgggattcag ccaccaattg atgtactccc gtctctttcg
    76021 cggttaaaag ataagggaac tggacccgga aagacaagag aagaccatgc agctacgatg
    76081 aatcagcttt ttgcagccta tgcacaagga aaacaggcaa aagaattagc cgtagtttta
    76141 ggtgaatctg ctttatctga tgtagacaag atctatgcga agtttgctga gcggtttgaa
    76201 aaagaatatg tcaatcaagg attctacacg aaccgttcga ttactgaaac acttgatcta
    76261 gggtgggaac tgctatcgat gttgccaaga accgaattaa aacgaatcaa agacgacatg
    76321 ctggacaaat atctgccaga agggaagtga gttctgatgg cacgattgaa tgtgaatccg
    76381 acccgcatgg aattgactcg attgaaaaaa cagttgacaa ctgccacaag agggcataaa
    76441 ttattaaaag ataagcaaga tgaactgatg cgtcaattca tcctgttgat tcgaaagaac
    76501 aaccagctgc gtcaagaaat ggaagagtct atgacagaag caatgtctga ttttgtattg
    76561 gcaaatgctt cgatcacgga acctttcatc gaagaattat ttgttttgcc ggcggaaaac
    76621 gttgatttgt ctatcgtaga caaaaatatc atgagtgtaa aagtacctgt gatgaatttt
    76681 gaatatgatg aacagctgac agacacacct ttggaatacg ggtatttgaa ttccagtgcc
    76741 gaactggatc ggtcaatcga tcggtttact accctgcttc caaaactttt ggaactgaca
    76801 gaaatcgaaa aaacttgtca actgatggcg agtgaaatcg aaaagacacg tcggcgagtc
    76861 aatgcattag aatatatgac gatccctcaa ttagaagaaa cgatctatta tattcgtatg
    76921 aagctggaag aaaacgagcg cgcagaagta acaaggttga tcaaagtaaa aaatatgggt
    76981 accactgact aagtggtatc tttttttaaa agaggaaaac gatgattaaa caaagcaaac
    77041 aaataaagaa acgtttgccg gctgttcagc ttctcgcatt aggatttttt ctcctgattt
    77101 tagttggcgg cggcctactt accctaccat tttttagtaa tagtgggcat gggacaaatt
    77161 ttatcgatgc gcttttcact gcaacttctg ctgtctgtgt aacgggattg acaacattga
    77221 atacagcaga gcattggaac agtgctggtc aatttttgat catgcttttg attgagatcg
    77281 gcggtcttgg ttttatgatg gttccgattc tatgctttgc attgataaag aagaaagtca
    77341 gtctcagcac acgtattata ttaaaagaag cgctgaatct agaagaagta tcaggtgtga
    77401 tgaagctcat gctttacatc ctaaaattgg cctttgttat ccaattgatt ggtacggttg
    77461 ctttatcttt tgtatttgtg cctgaatttg gctggttgaa aggtatctgg tacagtttgt
    77521 tccatgcaat ctctagtttt tgtaatgcag ggtttgattt gttaggagac agtttagcca
    77581 atcaccagca aaatgtttat ttgatcatgg tggtatctgc tttgatcatt tctggtgggt
    77641 taggcttcat cgtatggcgt gatttactgg aatatcatca gaaaaagaag atgacgattc
    77701 attcaaaaat cgcattaacc gttacaggta cccttttatt aggcggattc gttgtgttct
    77761 ttttcacaga gcgcaatggg gcaacgctag tggaagggaa tatgtttcaa cgattggcaa
    77821 acaccttttt tatgagtgtg acacctagaa cggctggata ttattcagtt gattacctcc
    77881 atatgagcca tgcaggtctg attttaacga tgtttttgat gtacatcggc ggaacatctg
    77941 ggtcgacggc cggcggattg aaaacaacta cgttaggtgt gttgctgatc cagatgcgtt
    78001 cgatgttgaa aggacgtacg agagcggaag catttggccg taccatccga caaggcgcag
    78061 tgttgcgggc acttacttta ttttttgtta cgttgacgtt gtgtgtagtc gccatcatga
    78121 ttttatcggt gactgaaacg atacctaaaa cttctggcat cgaatatatt gcttttgagg
    78181 tcttctctgc gtttggtaca gtaggtctta cgatgggatt gacgccagac ttgactgcaa
    78241 tagggaaatt gatcattata gcgcttatgt acattggacg agttggtgta ttgactgtgg
    78301 tcttctctct gatgacaaaa gcacaaagaa cacaatcaaa atacaaatat ccagaagaaa
    78361 gtgtcatgat tggataattt catcttctga cagaaaccta gtgatttagt aaaataagaa
    78421 aataaaataa tttttcttgc ttcttggata ctttaagtgc aaaatgttcg tttatttttt
    78481 gaggcactac ccgttgttga acctcgggta gtgcctcttt tttattgaaa ggaatcaata
    78541 agatttgatt cctttattta tcaataggtt ataattcata tttttttatt ttttctttta
    78601 cgatacttag tccagaagct aaaatttcaa ggttattaga ggatagggaa attcgaacga
    78661 atgcatctgg ttgcgcacgt gtagtaaagc gtctggaatg ataaagtcgg ataccgttag
    78721 caagaaagtc attctcaatt atcttagggt caatctcagg atcaactgga agaattcgat
    78781 agtaagggac acgattcgtt ggtttttcta ctttgaaaag agaatcaaaa agctgattgg
    78841 ctctttttgt aagacttaat ttagtttcta agatcctatt tgcttcattt gaatggagga
    78901 tttgagtgat gacttccaca tctaatccag aagttttcac atttatatta aaaattgctt
    78961 gttctatctt gctttggaca tgtactggaa ctacaagata agcaactcgc aatccagaac
    79021 aaataaattt tgtcattcca gctaagtaga ttgtttggtt aggtaataaa ttttggaaag
    79081 gaggaatgat cgtatgttga tagtaagttg ttaaaaatga atggatatca tcttcaataa
    79141 cccatagacc ttctttttca atcacttcgg ctaattgctc tcgtcttttg tgagagattt
    79201 gaaaccctat aggattatta caagaaggca taagaaagac accatgaatc ttcttttttc
    79261 tacattcctg aatcaatata tcaggtcgca ttccttgctc gtcaaaatca attggaacga
    79321 tctctaaatg atataactga gccaattcaa tgaaattagc gtatgtatat cggtctgttg
    79381 ctattctatc acctggagag aaaagtgcag aaagtgtgat agccaatcca ttttgaacac
    79441 cggaaacaat agatagagat tctaaggacg gaatgactcc ttgagttttt aaccaatttg
    79501 ctgcagtagt caattgaaaa tttgtgcctt tgggatcttg gtaattaagc aaaccaacaa
    79561 gatttgggtt attactagtt gattgaataa acgggacaac gaatttatta cattcttcaa
    79621 aagaactaac cagaccaaaa tcaatgatat gttcggttac ttcattggta gagatggtga
    79681 tggactcaaa gacattggga gaaataaatg tgccacttcc aatattcgta tacagcaaac
    79741 ctttctcaat tccatattta taagccttgc caacggtagt aaaatttaaa tctaaataat
    79801 cagctagctc tctttgggag ggtaactgag tgtttttctg taatttattc tttaaaatat
    79861 cttgttctaa ttgttgaatc aacgatcgat aataaggacg cttcaatttt tgtttgtctg
    79921 gtcgccaagt taacgggtaa ttgtcataag aattaatagg cattttctcc actccttaaa
    79981 attgtatacc atacaatttt accattgatt gtattgattt tagaagttaa tcttttgtga
    80041 ggagggaatt gtctatgaaa attattaatt ttgaggaagt agtagcttct tttagttttg
    80101 aagaagcgat tcaagtaatg aaaaaatgtt tttttgatta tgaaagtggt aaaatcagcc
    80161 aaaatcctcg attggtggaa attttacctg acggaaaagg caaaaatatg tttgcgatga
    80221 tgcctgctta tttgggggag aacagatatt ttggcacaaa agtcattacc gcttttccgg
    80281 ataatcatca gtatcattta ccttctcatt taggagagat tttcttgttt gatgctcaaa
    80341 acggactacc caaagcattg ataaacgcaa atgcagtcac ctggattcga acagctgctg
    80401 tatctgcgct ggcaacagat tacttagcaa atccgcatgc agaaacactt gctttaattg
    80461 gagctggtca acaagcattg tcgcatttga ctgcgatttc taccattcgt cccatcacta
    80521 cagtgtttgt ttacgatatt ttagaagaaa gacgaaatac ttttatcgct aaagctaaaa
    80581 aacagtatcc taaaataacg tttataaatg caatatcagt agaagatgca gtacgtccag
    80641 cggaaatcat ttgtacgttg acctctagta aagaggcatt tcttcaaaaa gagtgggtaa
    80701 gggaagacgc acatatcaat gctgtgggca catttactcc tgatacaaga gagataagta
    80761 catcgttgat ggaaacttct caaatctatg tagatgatta ctcagctgcc ttaacagaaa
    80821 gcggggacct gcttatagcc atggcagaag gagatttaga ggaatcttgt attgttggta
    80881 cattaggcga attagtttct gagaaaaaaa cattttataa aggagaatcg aggccgacga
    80941 ttttcgacgc agttggtcta gctattgaag atctttgttg tgcagaatat atttataaca
    81001 aattagagaa aggggcttta aaatgaactt agattattac gtagttgatg catttgcaga
    81061 tgaggtgttc aaaggaaatc cagcagcggt ttatgtgcta gaagaatggc tgccagaagg
    81121 tacgatgcaa aaaattgcca ttgaaaacaa tttatctgaa acagcattta cagtgaagaa
    81181 aaaccaagaa tttgagctta gatggtttac gccagatcga gaaatcgatc tttgtggtca
    81241 cgcgacatta gcaacagcat ttgttttatt taactattac aaaatacctg atgaaacgat
    81301 taaattttct actcaaagcg gtaatctatt tgtgacaaga attaaagatt attattacat
    81361 ggattttcct agtattatgc cgaaaaaagt gccgatattg tctgaatatg aagaagcgat
    81421 tggggctaag attaaagaag cctacttagc acgtgattta tttttcgtat tagaagatga
    81481 aaaaacggtg gctaaattgc agccagattt tacagctatc aaaaattttg aattaggaat
    81541 aggagtcatc gtgacagcag aaagtgtgca aaaagacttt gtttctagaa ccttctttcc
    81601 aaaattaaca atcaatgaag atccagtatg tggatcagca cattctaatc ttattcctta
    81661 ttgggcagaa agaatgaata aaacaaaatt gtcagcttat caaatgtcat caaggggcgg
    81721 ggatctagaa tgtgaattaa aagaagatcg tgtgataata ggaggaaaag cagttttgtt
    81781 ttctaaaggt acctcgttta tttgatttct ttcaaatgaa ttaaaaataa attggtggag
    81841 agtggcaacc ttatagctac aatggttgtt aaaaaaagac gcaaactttt tcaatttaat
    81901 gaaaagtttg cgtctcattt taattattgg tgtttgtttt ttattcaatc aagagtaaaa
    81961 tgccccatac taactatcct cggatgactt cgattttata accatcaggg tcaatgacaa
    82021 agtagtaaga aggcgcagtg ccaggtaatc cttttaagtc agtaatctca agaccggcag
    82081 ctttatgttg ctcgtgtaat ttttctagat catcagctgc tatagcgata tgaccatagc
    82141 cgtctcctag atcatacgca ccatgatcat agttgtaagt caactctaat tcatagtcat
    82201 ccccaggaag tgtcaaataa acaagtgtaa atttgttttc tggaaaatca cggcggcggc
    82261 tttcttcaaa accaaatgcc ttttgataaa attcgattga tgcttcaaga tctttcactc
    82321 gaacacatgt gtgagccatt ttcatagatt catctctcct tttcctttta ctcaatcata
    82381 acaaaaagaa gtaaggaaat agttgatttg tgcttgttca tgagaaattt ctcatgtaaa
    82441 atggatagaa aataaaactg ttaaggtgga aactattcat ggataaacca atttttggtg
    82501 aaaaaaagca atttgctgat tatcaaaccc gttatgcagc atatattgtc atagaaagag
    82561 atcagcagat tgcagtaatc gaggctccaa atggtgcttt ttttcttcct ggcggggaaa
    82621 ttgaaggaga agagacgaaa gaagaagcga ttgtccgtga gctgatagaa gaaatgggaa
    82681 ttgtggcaga aatttcttct tatctgggag aagctgatga gtatttttac tcgaattatc
    82741 gtgcaactta ttattataat ccaggatatt tctttgttgc tgattcttgg aagcgtatag
    82801 gagaaccaac tgaaaagacc aataaaattt ggtgggtgag ccctcaagaa gcgcttgtga
    82861 aattgaaacg tggtagccac cgatgggcag tcgagagatg gatcgaaaaa aataaaaact
    82921 gaaagaaagc gagtagatca gctttctctc agttttttta tttattacag tacatatttt
    82981 ttgattgctt cagctacacc gtgctcgtcg tttgatgaag tgatgacatt tgctgcttct
    83041 ttgacaagag aaacggcatt tcccattgct actcctagac cagcatattc aatcatggat
    83101 aagtcgttct cgttatctcc gatagccatg atttcatctt gatcaatacc aaggtgctgt
    83161 gcgagattcg caactgccgc acctttactt gcttctttat ttagtacttc gaagtaatag
    83221 ggcgcacttt tgaccgttgt gtatttatca cggaaagttt gcggtaaacg cgcaattgct
    83281 gcatctaaaa tttctggttc gtcgatcatc atcattttga cgatgttcat gtctggtgtc
    83341 atttcttcag gtgttcgata ttttagcggc atcttgacta aacttgcttc gtggatcgta
    83401 taagcgctga tatctcgatt aggcgtgtag atcgctttgt catcgatcga atggagatga
    83461 ctgccgacac ggcgtgccat cacttcgatc tctaggaaat cttcatgtgt cagtccgtga
    83521 cgggcgatga ttttacctga tttcgtttgt tgtacgagtg ccccgttata agtaataacg
    83581 taatcattat cttgaaaaag gttcaactcg tttaactgtt cctggacacc tggtaaggga
    83641 cggccagtgc ataaaacgat cgaaacacct tttgcaacag cagcggcaat cgcttctttt
    83701 acttcttttg ttacttctct tttctcattt aataaagtac catcgatgtc gatagcgact
    83761 agtttgatag acataatttc ctccaatata ttttaattta tttcaatcaa tgcgccatta
    83821 cggatatggc tggcaaattc ttgataagtt tcgtcaaata aatcataatg atcacgcaag
    83881 gacggatcaa ccatttcttt tggaaagaaa aatcgctcat ctccttgttc ttgtcccgct
    83941 aatgcagcaa caagctgact aacctgtgat aattctatca aagttccgtc atttcgcaaa
    84001 atctcgattt gtgtgcgatg tctgccttgt tctgggcgat aaaaatcata aggtagatcg
    84061 tagctagaat tcacagcagt gtaataaaca ggattatatc cgaccttttc tactaacaaa
    84121 gtgagttctt ggactaattt tgaatcccgg ttgccagaaa aagtagcaga tttcagtggt
    84181 ttacgattca aaaaacgttt agctaaatca tttaaaatag gatcagcaga ttcagaccat
    84241 tgagtaaagt aagtgcccaa gaccccatca tcaagtttga ggtattcttc taaagtaaag
    84301 cttccgtcaa gaaatggcag aagtaattga gaatggagtt caaaactgct ggcatcttct
    84361 tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa ttacttccat accacgggaa
    84421 acaggatgga agtacacttg cacatacatt tgatatcggc taacgatata atcttccact
    84481 gcatgcatgc cactcatgga aaaagcgatc ccgccttcat aaggacgaat cacacgtaat
    84541 attcgggtaa gatcaaatgt tccatattct gttccagtga aataagcatc ccgaagcaaa
    84601 tagtccattc gatctgcatc gatctgacta gaaatcattt ggacaacttg tgggttgggg
    84661 taagtttttt ggatcacact agctaccttt tcaggaaaac cttcttctac tcggttaaga
    84721 atctgataca cttctgtttc tggagaagtg atgatctcta cagtgatggc ttcatgattc
    84781 gtatggaaga tatgttcaaa tgtatgagag taaggaccat gaccgacatc atgcaacagt
    84841 gccgcacata aagtcaccag ccgttcctga tcatcccagc ctccgttgcc tattttttct
    84901 tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg aaatctcata aacgcctaat
    84961 gaatgagtaa aacggctatg ttctgctccg tgaaaagtga aagaagaagt gcctaattgt
    85021 ttaatgcgtc gtagacgttg gacttctttc gaattgatca aatctaagat tacttgatgc
    85081 tggacatgga tatagttatg gactggatca cgaaaaactt tttccatagg cagcatttga
    85141 tatttataag gggttgtcat aatgtagctc ctttatgtta ttacgttgtt ccattctctg
    85201 gatttggttg ttccattgct ccagctggat ttcttttttt agccagtcgg tagaatcctg
    85261 taaatcactt gcagaataca gcttttcaaa agcttttgca aatgcttctt tgacttcttt
    85321 tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc attgtagcag gatccactgc
    85381 aggatagcca tttgtaccaa agtcttcttt taaagcagat tgataaaatc gcttcatgac
    85441 ttgcccgcgt ttttcctgat taccgttgac acttaagtac atcataacag aaatcccatt
    85501 tttgatccga cgctgagcga taccggcaaa ttttttgcca tggatgctta aatcataagt
    85561 tccaggacaa taagaatggg tgatttcgaa tgcttgtatc ggtgcctttg gaaaagcgta
    85621 tttagtcaat aggagcattt gctcgtaagc gtcatctatg gttatttttt ttgtgtcact
    85681 ttgggggaaa atcaaagaaa tattcaaaat tccttcatct gatacgatcc ctaatccacc
    85741 tgaatttctg atcactggag cgtaacctgc atctttcagt gtttggatcc cgtcacttag
    85801 aaaaggagtt cgaacatcct tcatacctaa gatgactgtg cagtcatatt gccagaaatg
    85861 taaaaagatt tgctggtgtt ctttagaata ttccgttaat atatctgtta atgcaaaagg
    85921 ggaaaagtcg tttttttgat aaatgtgctg atctagtcga atcgcagggt tcattcaacc
    85981 ggctcctttg tataaattca tattttctac aatattatac tctaaaatca aagagttgtt
    86041 ttggaaaaaa ggttttctgt aaaaatggac aagttggttg acaaaacaaa agaaactagg
    86101 aacaatgtag ctatgagaag taaaggagaa tgaataatgg aattatcaca aggaacaccg
    86161 atttcaatca aattgcgtac aaaagtaaaa cagcaagggg aagtgcaaga tttttatttt
    86221 gatttgaaag ggcaaatggt gacaattggc gatacgctgt acatacgtta taaagagatt
    86281 caggaggaga cgggcgatga gattcctgta acgatcaaat tagttccaga tggtcatgta
    86341 cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat ttggctataa agaacggtta
    86401 gaaacatcct atcgaacacc atacggtatg atccagattg ctacttttac gaaagaactg
    86461 catgttagtt tgaaagaccg tcccacagga gggaaggttc gaatcgatta tgatctgttc
    86521 atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg attttacagc gtaaatataa
    86581 aagaaaagtt tgattttttg tgtctgattt tgtatgataa ggagtagact gtgaaaggac
    86641 gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca aaagcgaatt atcaatgatc
    86701 gaagtagcac acgcgatctt agaacaacgt ggcgatgtca tggatttttc tgatttagct
    86761 aaccagatcc aaaactatct tgggaaatca gacagtgaaa ttcgtgattc actcgcacaa
    86821 ttttatactg acttgaatat tgacggcagc tttatctcat taggggataa tcgttggggc
    86881 ttgcgttcat ggtatgctat cgattcgatc gatgaagaag taaaccatgg aatggacgaa
    86941 gaggatgaag atactccacg tcgccgtaaa cgcaagaaag tcaacgcctt tatcaatgat
    87001 gatgaagacg cgatcgatta caatgacgat gacccagaag atacagatct gacagaagaa
    87061 gatgacgatg atctgtttga tgacgatgat gatgaagatg aagaaatcgc tgcttataat
    87121 tctgacttgc aagaaatcgg agcagatgac ccgacagatg atgaagaaga cttgccagga
    87181 aatatcgaag aagatttaag tatcatagac gaagacgatg atgatgaaga ttatgaagag
    87241 gaagaatttt ctgactctga aaaagaataa acattatttt cttacgagag gttgtgacag
    87301 agacgatcag cctatcagaa taaggaggtg tgacacga
//
LOCUS       DAFTHM010000004        61562 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFTHM010000004 DAFTHM010000000
VERSION     DAFTHM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61562
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.004"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            138..656
                     /locus_tag="L7C88_000280"
     CDS             138..656
                     /locus_tag="L7C88_000280"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBP9557142.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            784..1467
                     /locus_tag="L7C88_000281"
     CDS             784..1467
                     /locus_tag="L7C88_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBP9557143.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1776..1849
                     /locus_tag="L7C88_000282"
     tRNA            1776..1849
                     /locus_tag="L7C88_000282"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1810..1812,aa:Arg,seq:tct)
     gene            2008..2367
                     /locus_tag="L7C88_000283"
     CDS             2008..2367
                     /locus_tag="L7C88_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBP9557144.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2490..4121
                     /locus_tag="L7C88_000284"
     CDS             2490..4121
                     /locus_tag="L7C88_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBP9557145.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4183..4824)
                     /locus_tag="L7C88_000285"
     CDS             complement(4183..4824)
                     /locus_tag="L7C88_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBP9557146.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5010..5086
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5106..5414
                     /gene="rplU"
                     /locus_tag="L7C88_000286"
     CDS             5106..5414
                     /gene="rplU"
                     /locus_tag="L7C88_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBP9557147.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5441..5785
                     /locus_tag="L7C88_000287"
     CDS             5441..5785
                     /locus_tag="L7C88_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBP9557148.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5798..6091
                     /gene="rpmA"
                     /locus_tag="L7C88_000288"
     CDS             5798..6091
                     /gene="rpmA"
                     /locus_tag="L7C88_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBP9557149.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6525..9332
                     /locus_tag="L7C88_000289"
     CDS             6525..9332
                     /locus_tag="L7C88_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBP9557150.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9523..10014
                     /locus_tag="L7C88_000290"
     CDS             9523..10014
                     /locus_tag="L7C88_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9557151.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10117..11106
                     /gene="manX"
                     /locus_tag="L7C88_000291"
     CDS             10117..11106
                     /gene="manX"
                     /locus_tag="L7C88_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBP9557152.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11139..11942
                     /locus_tag="L7C88_000292"
     CDS             11139..11942
                     /locus_tag="L7C88_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBP9557153.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11963..12877
                     /locus_tag="L7C88_000293"
     CDS             11963..12877
                     /locus_tag="L7C88_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBP9557154.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12960..13334
                     /locus_tag="L7C88_000294"
     CDS             12960..13334
                     /locus_tag="L7C88_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBP9557155.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13473..13718
                     /locus_tag="L7C88_000295"
     CDS             13473..13718
                     /locus_tag="L7C88_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBP9557156.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13890..14954
                     /locus_tag="L7C88_000296"
     CDS             13890..14954
                     /locus_tag="L7C88_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBP9557157.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15200..15625
                     /locus_tag="L7C88_000297"
     CDS             15200..15625
                     /locus_tag="L7C88_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBP9557158.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15618..16067
                     /gene="nusB"
                     /locus_tag="L7C88_000298"
     CDS             15618..16067
                     /gene="nusB"
                     /locus_tag="L7C88_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBP9557159.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16164..17018
                     /locus_tag="L7C88_000299"
     CDS             16164..17018
                     /locus_tag="L7C88_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBP9557160.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17019..18356
                     /locus_tag="L7C88_000300"
     CDS             17019..18356
                     /locus_tag="L7C88_000300"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBP9557161.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18361..18585
                     /locus_tag="L7C88_000301"
     CDS             18361..18585
                     /locus_tag="L7C88_000301"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBP9557162.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18587..19477
                     /locus_tag="L7C88_000302"
     CDS             18587..19477
                     /locus_tag="L7C88_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBP9557163.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19486..20304
                     /locus_tag="L7C88_000303"
     CDS             19486..20304
                     /locus_tag="L7C88_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBP9557164.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20411..20860
                     /locus_tag="L7C88_000304"
     CDS             20411..20860
                     /locus_tag="L7C88_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBP9557165.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20878..22560
                     /gene="recN"
                     /locus_tag="L7C88_000305"
     CDS             20878..22560
                     /gene="recN"
                     /locus_tag="L7C88_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBP9557166.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22615..22731)
                     /locus_tag="L7C88_000306"
     CDS             complement(22615..22731)
                     /locus_tag="L7C88_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBP9557167.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22804..23760)
                     /locus_tag="L7C88_000307"
     CDS             complement(22804..23760)
                     /locus_tag="L7C88_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBP9557168.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23931..24299
                     /locus_tag="L7C88_000308"
     CDS             23931..24299
                     /locus_tag="L7C88_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBP9557169.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24469..24900
                     /gene="mraZ"
                     /locus_tag="L7C88_000309"
     CDS             24469..24900
                     /gene="mraZ"
                     /locus_tag="L7C88_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBP9557170.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24921..25880
                     /gene="rsmH"
                     /locus_tag="L7C88_000310"
     CDS             24921..25880
                     /gene="rsmH"
                     /locus_tag="L7C88_000310"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBP9557171.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25885..26286
                     /gene="ftsL"
                     /locus_tag="L7C88_000311"
     CDS             25885..26286
                     /gene="ftsL"
                     /locus_tag="L7C88_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBP9557172.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26287..28479
                     /locus_tag="L7C88_000312"
     CDS             26287..28479
                     /locus_tag="L7C88_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBP9557173.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28505..29467
                     /locus_tag="L7C88_000313"
     CDS             28505..29467
                     /locus_tag="L7C88_000313"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBP9557174.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29481..30842
                     /locus_tag="L7C88_000314"
     CDS             29481..30842
                     /locus_tag="L7C88_000314"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBP9557175.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30868..31956
                     /gene="murG"
                     /locus_tag="L7C88_000315"
     CDS             30868..31956
                     /gene="murG"
                     /locus_tag="L7C88_000315"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBP9557176.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31971..33191
                     /locus_tag="L7C88_000316"
     CDS             31971..33191
                     /locus_tag="L7C88_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBP9557177.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33347..34672
                     /gene="ftsA"
                     /locus_tag="L7C88_000317"
     CDS             33347..34672
                     /gene="ftsA"
                     /locus_tag="L7C88_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBP9557178.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34695..35936
                     /gene="ftsZ"
                     /locus_tag="L7C88_000318"
     CDS             34695..35936
                     /gene="ftsZ"
                     /locus_tag="L7C88_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBP9557179.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35953..36630
                     /locus_tag="L7C88_000319"
     CDS             35953..36630
                     /locus_tag="L7C88_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBP9557180.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36644..37243
                     /locus_tag="L7C88_000320"
     CDS             36644..37243
                     /locus_tag="L7C88_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBP9557181.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37258..37545
                     /locus_tag="L7C88_000321"
     CDS             37258..37545
                     /locus_tag="L7C88_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBP9557182.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37594..38376
                     /locus_tag="L7C88_000322"
     CDS             37594..38376
                     /locus_tag="L7C88_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBP9557183.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38397..39104
                     /locus_tag="L7C88_000323"
     CDS             38397..39104
                     /locus_tag="L7C88_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBP9557184.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39366..42164
                     /gene="ileS"
                     /locus_tag="L7C88_000324"
     CDS             39366..42164
                     /gene="ileS"
                     /locus_tag="L7C88_000324"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBP9557185.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42213..43739)
                     /locus_tag="L7C88_000325"
     CDS             complement(42213..43739)
                     /locus_tag="L7C88_000325"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBP9557186.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43754..44401)
                     /locus_tag="L7C88_000326"
     CDS             complement(43754..44401)
                     /locus_tag="L7C88_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBP9557187.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44585..44914)
                     /locus_tag="L7C88_000327"
     CDS             complement(44585..44914)
                     /locus_tag="L7C88_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBP9557188.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45091..45819
                     /gene="sfsA"
                     /locus_tag="L7C88_000328"
     CDS             45091..45819
                     /gene="sfsA"
                     /locus_tag="L7C88_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBP9557189.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45835..46848
                     /locus_tag="L7C88_000329"
     CDS             45835..46848
                     /locus_tag="L7C88_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBP9557190.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46848..48125
                     /locus_tag="L7C88_000330"
     CDS             46848..48125
                     /locus_tag="L7C88_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBP9557191.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48188..50890
                     /locus_tag="L7C88_000331"
     CDS             48188..50890
                     /locus_tag="L7C88_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBP9557192.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51042..51359
                     /locus_tag="L7C88_000332"
     CDS             51042..51359
                     /locus_tag="L7C88_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9557193.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51389..51709
                     /locus_tag="L7C88_000333"
     CDS             51389..51709
                     /locus_tag="L7C88_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBP9557194.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51817..53307
                     /locus_tag="L7C88_000334"
     CDS             51817..53307
                     /locus_tag="L7C88_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9557195.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGANNNKMNVRSGTL"
     gene            53347..53568
                     /locus_tag="L7C88_000335"
     CDS             53347..53568
                     /locus_tag="L7C88_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557196.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53599..53781
                     /locus_tag="L7C88_000336"
     CDS             53599..53781
                     /locus_tag="L7C88_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBP9557197.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53781..54194
                     /locus_tag="L7C88_000337"
     CDS             53781..54194
                     /locus_tag="L7C88_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBP9557198.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54317..55498
                     /locus_tag="L7C88_000338"
     CDS             54317..55498
                     /locus_tag="L7C88_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9557199.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55569..55733)
                     /locus_tag="L7C88_000339"
     CDS             complement(55569..55733)
                     /locus_tag="L7C88_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557200.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55887..55960
                     /locus_tag="L7C88_000340"
     tRNA            55887..55960
                     /locus_tag="L7C88_000340"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55921..55923,aa:Arg,seq:cct)
     gene            complement(56029..57168)
                     /locus_tag="L7C88_000341"
     CDS             complement(56029..57168)
                     /locus_tag="L7C88_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBP9557201.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEVK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(57284..57919)
                     /locus_tag="L7C88_000342"
     CDS             complement(57284..57919)
                     /locus_tag="L7C88_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBP9557202.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLILLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTAKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAQNNVLQAQTGYFGTETVSIALHN"
     gene            complement(58002..58424)
                     /locus_tag="L7C88_000343"
     CDS             complement(58002..58424)
                     /locus_tag="L7C88_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBP9557203.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFETEADRIAIMILLNIFIENELTDE
                     SQFKLENFMEFYSINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            complement(58442..58762)
                     /locus_tag="L7C88_000344"
     CDS             complement(58442..58762)
                     /locus_tag="L7C88_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9557204.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            59062..59202
                     /locus_tag="L7C88_000345"
     CDS             59062..59202
                     /locus_tag="L7C88_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557205.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            59500..59757
                     /locus_tag="L7C88_000346"
     CDS             59500..59757
                     /locus_tag="L7C88_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HBP9557206.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(59728..60036)
                     /locus_tag="L7C88_000347"
     CDS             complement(59728..60036)
                     /locus_tag="L7C88_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557207.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            60114..60860
                     /locus_tag="L7C88_000348"
     CDS             60114..60860
                     /locus_tag="L7C88_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBP9557208.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            60875..61078
                     /locus_tag="L7C88_000349"
     CDS             60875..61078
                     /locus_tag="L7C88_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557209.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            61094..61414
                     /locus_tag="L7C88_000350"
     CDS             61094..61414
                     /locus_tag="L7C88_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBP9557210.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRR"
     gene            61419..>61562
                     /locus_tag="L7C88_000351"
     CDS             61419..>61562
                     /locus_tag="L7C88_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557211.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYR"
BASE COUNT        20379 a        10398 c        13003 g        17782 t
ORIGIN      
        1 aaatgagata aagatgagga aatagaatta gaaacatata attattaaag ggaaacattt
       61 ttacagctat aatttgaaaa aaatttatcg ttattatatg attaagaagg attgaataaa
      121 gaaagaagtt gaaaacgata cctgattaca aaaaaataac ttttataagt tctataacgt
      181 tgattatatt tttaattctt attcttctcg tcgtcttggt tccccgaatt tttggtttga
      241 ctccttatat tattgaggac aaagaaatga gtccatatta tgcacaagga aatctgatat
      301 atgtacgacc gaaaaataca aatgagattt tagtcggaga tattattaca tattatgaaa
      361 attcaggaaa aaaaatctcg acgcgtcgcg taatagccgt tgaaaacaac cacgaagatt
      421 tttatacaaa agctgataca aagacttata ttgagcctgg agtagtaaaa aagagaaata
      481 ttatcggtag tcccatcttt cagattccat atattggact agtcctttca aaaacggcat
      541 ttgcatggat tcaggggtta ttctttacga ttgctttttg cctaacagga atcacagcat
      601 ggaatacctt tgtagagttg aaaaagaagc ggagacgaac acagaaattt ttgtaagaat
      661 gttaaaaaca taaatgtatt ccagagatcc aacgactctt ctgaacatga aacacgagaa
      721 aacactcatg cagcttgtag atttagtcag ttgttcgtat aatgtgtgaa gaggaggagt
      781 agtatgcgca atgaaatgat gcatcgtcct gtagtcaaag aagaactatt ggattttatg
      841 cgtacccagc aaaaaaaatt accgggtgag ctaggcaaac tggaagaaga agctcatgta
      901 gcagaagtac cagttattcc ccatgaaaca gttgtatttt tgaaattttt acttggacag
      961 cttcagcctg aacgaatctt ggagatcgga gcagctatcg gtttttcatc aagtgtcatg
     1021 gccacgacaa tcggagaaaa cgctcatgtt acgacaattg atcgtttcga tgtcatgatc
     1081 gagaaagcta aaaaaaacta tgaacgtcta ggactgacag ataaagtgac tttgcttgaa
     1141 ggtcaagcag cagatatctt gccggagttg tctggtccgt atgactttat ttttatggat
     1201 agtgcaaaat caaaatatat tgaattttta cctgaatgct tacgtttgtt aagaaaaggt
     1261 ggcgttttga tggtagatga catcttccaa ggaggaacga tcttgctccc agatgaagag
     1321 attccccgtg gcaaacgagc tatccatcgt aaattaaatg aatttcttcg tgttgtgatg
     1381 gatcatcccg atttgacatc gacaatcttg ccattaggtg atggtgtgat cttaatgaca
     1441 aaggaatcag aaacaatcga gttgtgatac atgattatgg cagcctgtag ataatcgatt
     1501 gaatcgaggg ctcaattcga acttgatgta aaagtttcta tatttgtaag tcaattaaag
     1561 gatacaggaa atctaaataa acaggagtag catgaagtca atgtagctcc tgttttcaat
     1621 tgataacctt agaacagctg aaggagaatg tctcgtttta aaagattgat ttagtagttg
     1681 ggccaaaata attcattatt tgctaattaa ataactattt cgtattgaca gaagcaattt
     1741 aattatctat aattattgat gttccgctga ttcttgtcat agtagctcag ctggatagag
     1801 catccgcctt ctaagcggac ggtcgggggt tcgaatccct cctgtgacgc taaaaaaccg
     1861 ttagaaactg aggtttctaa cggtttttct ttgttttttg tgccaatatt gtttgttttc
     1921 aaaggcaaat aaaataaaaa aacatcctta tcgagtacaa ttataaggag caaaaaaata
     1981 aaactcatca gaaaagagga agaagatatg acgatactat ctagaatttt agtgactcta
     2041 gttgcaattg aattttttta tatcatgtat atcgaaacgg tgagaactga ttctgacacg
     2101 acaagtaggg tttttaaaat gagtaaagaa gagttaagca gaaaatctgt tcaaacattg
     2161 tttaagaacc aaggagtgta caatggacta ttaggagtgg gactacttta tggagcttat
     2221 ctttcttccg catctaaaga aatcacaagt atgctattaa tatctatttt ttttgttgca
     2281 ttatatggca gtttgactag cgatcgttgg attttactca aacaaggtgg gctagctctg
     2341 ttggcattgc tttctatttt cttataaata tagaaaaaat aagaatttat ctaacaggaa
     2401 actttgtgaa aaatattact ttatctcatg aaatatgata ttctaatgaa tggtatttta
     2461 gaaaatttca tgaaaaagga gttagatagg tgttcaaaaa ttatgtttcc tcactaaaaa
     2521 aagaattttc aggttatgat ctttcaagat ttcagaaaga tcttttggct gggatcacag
     2581 tagctgctgt agcattgcct ttagccttgg cttttggggt atcaagcgga gctgatgcgg
     2641 ccgcaggttt gattacggct atcattgccg gtatcgttat tggcggttta tcaggcggtt
     2701 tttatcaaat atcaggtccg acaggtgcga tggcagctat cttgatgtct attgcggcaa
     2761 caaagggaat gcaaggtgta ttgcttgcta cttttttagc gggtctattt ttacttgcag
     2821 caggactttt ccgattagga acactgactt cttttatccc agcacccgta attacggggt
     2881 ttacttcagg tattgctatc attattgcat taggtcagat cgataattta tttggtgttc
     2941 actcggaagg tacaaacgtt attgaaaaac taagtagtta tcaaacgata ggatttccga
     3001 taaacacagc ctctttgatc atgggagggc tagtcatttt agggatgttt atctatccaa
     3061 aaaaatgggc gaaacgaatg cctagttcgc tgctggctat cattttggca acagcagtta
     3121 tgctattgtt ccatttacca gtagcaactg tgggtaagat tccacaaaca ttgatcagta
     3181 gtaatcgttt gaatatggga gattttagct tttctgcctt gcaacaagtg gcagttccag
     3241 ctattagcat tgctttatta ggaatgattg aaagcttgct atgtggtgct tcggctggcc
     3301 gaatggcaaa taagccctta gatagcaatc aagaattaat ggcgcaagga attggaaatc
     3361 tgttgcttcc tttctttggc gggattcctg ctactgcggc catcgcccgt acaagcgtgg
     3421 ccatcaaatc tggtgcacaa actagattag ctggtatgat acatgcagtt gtcttactgc
     3481 tctccatgct tgtttttgcg ccagtgatgt cacagattcc aatgccagca cttgcaggtg
     3541 ttttgattgt gacggcttgg cgtatgaatg aatgggaaac gatcaaggag ctatttacta
     3601 ataaatattg gtcagcagtt ctattgttta tccttacgat gatttgtaca gttatctttg
     3661 atttaagtat tgctatcgtg atcggggtga tcggcggctg tgtatttttt gttgtcaaaa
     3721 gcgctgctat cacgatttca ttagaaacga tcgattggca aagaatgggg ctgccagaaa
     3781 cggaaaagct gaataactgg acagtagtgt atattagtgg tccactgttt tttatgtctt
     3841 cagaaaaact caaaaataaa ttggaagaac taaatcatca cgatggtgtc attttctcca
     3901 tgcgaggcgt accaagtatt gatttgacgg cacgtgcagt ttttgatgaa tttcaagaaa
     3961 aagcagagca aagaggacaa acgattatct atacttcctt gcagccagaa gtagaaaaac
     4021 aactttctca cttgtgggaa catacattca cgcatcaaca tcaaacagtt gctcatgcgt
     4081 tgacagcttt acatgcgaaa tatactgcaa ttagccatta aaacaatgaa aaagaacaga
     4141 caagactgta aactgaagat tttatggtct tgtctgttct ttttaatatt gctgtaaaag
     4201 tgaagctagt acttgccagt cttgatggat aacaggtaca agggagcgat tgtagaaaat
     4261 agctgctgga tgaaaaagtg gaagaattcg atagtttttt tctgaccatt cgtaggcatc
     4321 cttttgttct gttaattgta agacaggccc tgtatagagt tgaccatgat ttttggtaac
     4381 cgtatattct ttgccaagta aacgttgaag accaatgttt ccaagtgtcg caattaattt
     4441 tggctggacc ttcatcagtt cgtaatccaa tattggtgca tgcgcaaata cttcggaacg
     4501 agtaggtgtc cgatttggat aaacagtttc tgactgttgt gtccgtttat tgatccgatg
     4561 agtcacgcga tacgggcggc tccttacagc actggtgata tacacctctt ctcgtgttaa
     4621 gccagttgaa gaaagtgcct gcatcaattc ttttccagct tgaccgctaa aaggaacatg
     4681 cgtatcaatc tctgttttcc ctggggcttc tcccacgagc atcagtttag gatgaagagg
     4741 tccttgccca gcgataaatc cttctacagg acggccgttc attcttaaag aagcttcttg
     4801 tatcagttct tttgggtatt ccatttatgc tcctcctttt tcttttatta taagaataaa
     4861 agaaacacaa tgcgactatt ttatttggta gaactgtgag gatagaaaag cagaagtatt
     4921 gcttgaattt ttgttttact ttttgatttt aaatttagtt gactaacggt tgctgttctg
     4981 gtaagctagt actgttgtaa ttgtggactc cacagctaca accgctcaga acaagtaata
     5041 agcacagcat atgctgtcac ttcggatggc gagtctaagt atatcagaag gaggtgcttt
     5101 atagcatgta cgcaattatt aaaactggtg gtaaacaagt aaaagttgaa gtgggacaag
     5161 caatctatgt tgaaaaactt gacgttgaag caggagaaaa agttgttttt gacgaagtta
     5221 tcttagtagg cggagaatct acaaaagtag gcgctccaac tgttgcaggt gcaactgttg
     5281 aaggtactgt tgaaaaacac ggcaaacaaa agaaagtcgt tactttcaaa tacaaaccta
     5341 aaaaacattc acaccgtaaa caaggtcatc gtcaaccata tacaaaagtg gttatcgacg
     5401 cgatcaacgc ttaatagcgt ttgagaaaga aggcctatat atgatcaaag gaacatttaa
     5461 gcgaaatgac gcaggtcaga tcgtttcatt cactttgacc gggcatgctg atgctggtcc
     5521 ttatggaagt gatatcgttt gtgcgggtgt ttctgcgtta gcgatcagca ctgtcaacgg
     5581 gattgcctca ttagccggtt ttgagccgat tgttgaaatg aatgaagaag aaggcggtta
     5641 tctttatacc gaagtcactt caggaatgac acaagaacaa aacaatattg ctgagattct
     5701 attagaaaat cttttattag gattacaatc gatagaagct gaaaactcag aatatatcca
     5761 aattaaaaca attaatgata aataggaggt gcagaccatg ttgttatcta tgaatctaca
     5821 attatttgcc cacaaaaaag gtggcggttc tacatctaac ggccgtgact cagaatcaaa
     5881 acgtctaggt gctaaacgtg ctgatggaca aacagttaca ggtggatcaa ttctttaccg
     5941 tcaacgcggt acaaaaatct atccaggtgt aaacgtgggt atcggtggag acgacacttt
     6001 atttgcaaaa gttgatggcg tagtacgttt cgaacgtaaa ggccgtaaca aaaaacaagt
     6061 gtctgtttat ccagtagctc aagaagctta attgaatctt atgattaaag aggttgtgac
     6121 aagacttttg tcacagcctt ttttgtttat aaaaataaaa gttgtagtgg aggctacgaa
     6181 gtttactttg tctttttaca cttaatattt ttttgccaat ttggaatcag gatgttttga
     6241 taactatcgt tttcaattga tggaagctat attgtttgct atcagtgaaa taattatatg
     6301 gtaaacagtg ttctttttct tgtttccatt ataaaaatcg tatcgggatt tttcgttctt
     6361 ttaaattgaa catttctatc tatccgcgtg ttatcaacaa aacaaaatca ggtaaatagt
     6421 tgacgaaaca gaaataaata catagtatta tgttttgaag cctaagtaca atagtctata
     6481 gaaaaggagc gataccattg gcaaaacgca ttgaccgaat ttatatgtat gtcaaagaaa
     6541 aaaccgctca tttaacaaag gcagaatatg atcaaggagt aacaacacag gaaattgctg
     6601 aagtgttagg gattcagcga acaaatagca gtaaagatct gaatcagcta gtgcgcgaag
     6661 gaaaactgat aaagacagac ggacgaccag tacgttacat atatcaaaca ctcgttacgc
     6721 acgtaaagcc agttacaaaa catgtagtca gttacaaaga aacgccggtc tctgaagaaa
     6781 aaaatacact ccaaatagat actaaggata tctttgcaaa aatcattgga gctaacggca
     6841 gcatgaaaaa ttcagtggaa caggcaaaag ctgcgatttt gtatccgcca agaggattaa
     6901 attgtttgat tacaggacct accggatcag gaaagactta ttttgcacac gcgatgtatc
     6961 attttgcaaa agcgcatcat gtaatagatg aggaaacgga actgattgtt ttcaattgtg
     7021 ctgattatgc caataaccct gagcttttga tgagtcattt atttgggtac gcaaaaggtg
     7081 cttttacagg cgcagatgaa gaaaaaatgg ggattatcga tcaagcggat ggcggtatgc
     7141 tgtttttgga tgagattcac cggttgccgc ctgaaggtca agaaatgatc ttttacttta
     7201 tggatcatgg aacttacagt cgtcttgggg aaacaacgaa atcccatgaa gcaaatgtac
     7261 ggatcgtagg tgcgaccaca gaagacccag gttcttctct attagaaact tttgttcggc
     7321 gtatcccaat caatatcaaa cttccggctt ttgaaaaacg tcctgcaaat gagaaagtcg
     7381 atttagtaaa aatcatgatt gcccacgaag caaaccgcac gcagcgaaag atttctttga
     7441 cagaagatgt agcaaaagca ttgatcggca gtgtgaccta tggaaatata ggacaattga
     7501 agtcaaatat ccagttagta tgtgcacgag gatttctaaa tcatatgcaa tcacccgaaa
     7561 tctcgatcac aatcgatgat ttgacagaag ggattcgtag cggattgatt caattagcaa
     7621 gcaaccgcag tgcaatggca gagctttcta aaatattgga gccaaagata actgtagcac
     7681 caaatgatac gatcatgaaa atccaatcgg actcctatga gttaccttat aatctatatg
     7741 atatcatcgg agataaagca gctttactga agtcggatgg tttggatcaa gaagcaatca
     7801 atcatttcat ttctacagat atcaacatcc atctgaagtc tttctataaa gaccatggtt
     7861 tttcttttaa tgcagacagc aaattagcag aatttgtaga tccgaaaatc atagaagtga
     7921 ccaatcagat ttatgtaatg gtcaaaagat ctttaccata tgagtttcag caaaacttta
     7981 tttatgctat gagcttgcat atcagttctt ttttgaaaaa aatcaactta ggagaagaac
     8041 ggcatacgaa tgataacatc cgtgagatgg cttttgattt tccagatgaa tatgctgttg
     8101 cgaaagaagt gcgtagttat atcgaaacgt attttcaagt ggagattcca gaaagtgaag
     8161 actattactt gaccgttcta ctcgtctcgt tacgggcaaa tcaagcaagc ggcagaatcg
     8221 gtgtagtcgt tgcagctcac ggaaacagca cagcaagcag tatggtccaa gttgtccaac
     8281 agttgttaga tgcagagaac gtacgagcag tagacatgcc tttggatatg gatccgaaaa
     8341 cagcattgga ccgaattgaa cgcaatgtac aagaagtaga tgaaggaagc ggggtcatac
     8401 tcttagtaga tatggggtcc cttgcgtcgt ttaattcgca aattcaaaga gacactggaa
     8461 ttccagtacg tactgttgat atggtaacaa cttctctagt tttggaaact gtacgaaagg
     8521 tctcagtatt agggacagat ctagatatgt tgcatgaatc attgaaaaat tttcgaggtt
     8581 acgcagaaat atcttctgta gaatctgttc aggaagcaaa acctattcat aagaaaaaag
     8641 ctgttttggc tatctgcgca tctggcgaag gtacagcaca aagaatcaaa gaattgatcg
     8701 aacgagcggt aaacaagcgt caagaaacag aattagaagt tctagctttg tcgattgtgg
     8761 aagtgaaaga agaactgcca gttatccaaa aagaatatca gatcatagct actactggga
     8821 ttactgattt gaatatccaa gccccattta ttcctttaga acgttttatt gatcaaaata
     8881 tcgaagtcat tttggatcag ttgctgatgg aatcagaatt ggaggaaact gaattcatct
     8941 ccctagatga agagtcagct aaaaatacgt gtgttgagtt tatctctgat aacttcatct
     9001 ttattaatgg tagtaagtta atcgatccaa tgtggcaatt ttctacacaa atctctcaga
     9061 cgacgggaat cggcgatgaa gaatatggat tcaaaatcaa cctagtgatg cacacagcag
     9121 gaatgatcga acgtattatt cggaatgaac cattgactgt ggaagaaaac gaattgacaa
     9181 atacaacgaa tgatcctctt tatagccaat tggcagcctc agttgttctg ttggaagatc
     9241 agataaaagt aaaagtgccg atagaagaaa tgtattatct gctacgtcta gtccataatc
     9301 agttagataa aaaagaatac actgtgccat gaatacacaa aaacgataca cttttatagt
     9361 gtatcgtttt tgtgtattgg ttaagaatcc tttaaattca attagtgtat cgtaaaaaag
     9421 ttggcacgct ttttgcttat agtagtgtgt gctaggaggt ggttgttcac acagaaatga
     9481 taggggtttc tgtgaagtag tgaggaagaa ggagttttgc agatggatat tcgattggca
     9541 cgtatagatg atcgtttaat ccacgggcaa gtcgcaacag tttggtcgaa gcaaacaggt
     9601 gttgaacgta tcattgtgat cagcgatgta gtcgctcaag ataaattgag aaagtttcta
     9661 ctaaaagaag ctgcaccgcc ggggatcaca gcaaatgtaa taaccgtgca gaaaatgatt
     9721 caaatctatc atagtggatt attatcacga gcaaaagtga tgcttttatt caccaatccc
     9781 caagatgttg aagcggttgt ccgctgcggt gtacagttga agtcgttgaa tatcggcggt
     9841 atgagtttta ctgaaggcaa atcaatgatt accaattttg tttcagtaaa tcaacaagat
     9901 attgattcct ttcgttactt gaacagtcaa gaagtggagt tagagattcg aaaagtacct
     9961 gctgacagga aaatcctttt gatggaacta ctagcgaaaa tcaaaaaggt gtagcaagaa
    10021 tggttgttgg aaaaggtcaa ataattctgt tgtaatggtt agcaattatt aatatttttg
    10081 aatttgttac aacaaaagta aataggaggt ataaatatgg tagggattat cctagcaagt
    10141 catggacaat ttgctgaagg aatcttacaa tccggttcaa tgatctttgg cgaacaagaa
    10201 aacgtcaaag ccgtgatttt gaaaccaagt gaaggtccag atgacttgag agccaaattg
    10261 gaagaagcgg ttgcttcttt tgataatcaa gacgaagtgt tattcttagt tgatttatgg
    10321 ggcggaacac cgttcaatca atcaaacaca ttattcgaag agcacaaaga taaatgggca
    10381 atcgtcagcg gtttgaattt accaatgttg attgaagcct acgcatcacg cttttcaatg
    10441 gaatctgctc atgaaattgc agcacacatc attgaaacag caaaagacgg tgtaaaagta
    10501 aaaccggaag aattagaacc ggcagaagca ccgaaagcag cagttgaaga cgcacaacct
    10561 aaaggagcac ttccagaagg aactgtggtc ggagacggaa aaatcaaata tgtattagca
    10621 cgtgttgact cacgtctgtt acatggacaa gttgcgacag cttggacaaa agcagtgcaa
    10681 ccaaaccgta ttatcgttgt ttcagatgca gtatcaaagg atgatctgcg taagagacta
    10741 atcgaacaag ctgctcctcc aggtgtaaaa gcaaatgtta ttcctattag caaaatgatc
    10801 gaagtagcaa aagaccctcg ttttggaaat accaaagcat tgcttttatt tgaaaatcct
    10861 gaagacgtat tgacagctgt tgaaggtggc gtagacatca aagaattaaa tgttgggtca
    10921 atggcgcatt cggtcggtaa agtcgttgta agtaaagtat tgtctatggg acaagaagac
    10981 gttgaagcgt ttgagaagct tgaacaaaaa ggtgtgaaat tcgatgtacg taaagtacct
    11041 aatgattcac gcgataacat ggatgatatt ttgaaaaaag caaaagctga attagcaaaa
    11101 gcgtaataaa taatattaaa atttatagga ggcttatcat gtctattatt tcaataattt
    11161 tagtcgtatt agttgccttt ctagctggta tggaaggtat tcttgatgaa tttcaatttc
    11221 atcaaccact agtggcatgt acattgatcg gtttagttac cggtaacctc gaagctggta
    11281 tcgtacttgg cggtacgctt cagatgatcg ctttaggttg ggcaaatatc ggtgccgctg
    11341 tagcaccaga tgctgcatta gcatcagtag catcagcaat tattttagtt ttaggtggac
    11401 aaggtgttaa aggtgttcct tctgcgatcg cgattgccgt tcctttggct gttgcagggt
    11461 tgttcttaac aatgatcgta cgtacaatcg ctgttccaat cgttcatttg atggatgcgg
    11521 ctgctgaaga aggaaacatc cgtaaggttg aaatgtggca catcattgct gtatgtttac
    11581 aaggggttcg tatcgcggtc ccagcagcag cgttgctatt tatcccagca caaactgtgc
    11641 aatcattcct tgaatcaatg ccagcatggt taacagatgg tatggctatc ggtgggggaa
    11701 tggtcgtagc tgtaggttac gctttggtaa tcaacatgat ggctacaaaa gaagtatggc
    11761 cattcttcgt tattggtttc gttgtagctg caatttctca attaacattg attgctctag
    11821 gtgctttagg tgttgcatta gctcttattt acttgaacct ttctaaaatg ggtggttcat
    11881 caaataatgg aggcggaagc aactctggtg accctttagg cgacattttg aatgactatt
    11941 aatcttgaag gaggaaaata aaatggcaga agaaaaaatc aaattatcaa aaaaagatcg
    12001 tttagctgtt gcgtggcgct ctaccttcat tcaaggttca tggaactacg aacgtatgca
    12061 aaacggtggc tgggcatttt ctatgattcc agcaatcaaa aaattataca aaacaaaaga
    12121 agaacgttct gcagcattaa aacgtcactt ggaattcttt aatacacacc catacattgc
    12181 ttctccaatt ttaggggtta cattggctct ggaagaagaa cgtgcgaatg gcgcgcctgt
    12241 tgatgatgta gcgattcaag gggttaaagt aggtatgatg ggtcctttag ctggtgttgg
    12301 tgacccagtg ttctggttta cagtacgtcc aatgctaggt gcactaggtg cttcattagc
    12361 tatgggagga aatatccttg gaccaatcat cttcttctta ggttggaaca ttattcgttg
    12421 ggcattcatg tggtatacac aagaatttgg ctacaaagct ggttctaaaa ttactgatga
    12481 cctttctggc ggattgttac aagacgtaac aaaaggtgct tcaattttag ggatgttcgt
    12541 attagctgcc cttgtacaaa gatgggtatc aatcaaattc ttaccagttg tatcaactgt
    12601 aaaattagat aaaggtgctt acatcgaatg ggataaattg ccttcaggtg gtgaaggaat
    12661 caagagtgca tttgaacaag ttaataatgg cttagccctt tctcctgaaa aggtaacaac
    12721 attacaagac aacttagacc aattgattcc tggtttagct gcattaggat taacattgtt
    12781 atgtatgtgg ttgcttaaga aaaaggtttc tccaatcgtt atcatccttg gtttattcgt
    12841 agtcggtgtt gttggacacg tcatcggact tttataatcc ataaaaatat agctcgggcg
    12901 ttgtcccgag ctttttttat atagtatact gttcataaac aaatatctgg agggagaaaa
    12961 tggttcaatc aatcaataca aaagtagact tggtaattga tgctacttcg tttacgggtc
    13021 tgacagatta cgggcaaatc atgataggtg ataatggttt tgagttttac catgcgcgag
    13081 atagacgcaa atatatccaa attccatggg aagaagtgga ttatgtacta gcatcagtca
    13141 tgctaaaggg aaaatggatt cctcgatatg ccattcaaac gaaaaaaaat ggtacataca
    13201 cattttcttc caaagaacct aaaaaagtgc ttcgtgcgat cagagaatat gtagatgaag
    13261 atagaatggt acaatcattg agtttctttg atgtagtgaa acgtggtatt cgtagtatgt
    13321 ttaaacgcaa gtaaaaaata aagaaaactt ctaagaggag gttttcttta tttttttact
    13381 ttgcagaaga aaatatgaaa tagcaaaacc aattatttgt cccctttaaa tcccatatgc
    13441 taaaattgat tagcaaagaa ggaggttata ttatgagttg gttatggaca ttgattgttg
    13501 gagccgtgat cggagcaatt gcaggtgcga tcaccagtaa aggaaattcg atgggctgtg
    13561 taacgaatat cattgctgga ctagtcggtt caagtattgg acaagcgatt ttcggcgaat
    13621 ggggaccaaa agctgcaggt atggcactta ttccatctat tttaggcgca gtgattttgg
    13681 tagcagttgt ctcatttttc tttggaaaac gatcataagt ttttacaaaa tagtaaacta
    13741 aaaggagttg cagcgagact gtgactcctt tttggcttta tttatttaaa ataaaaagaa
    13801 gttttccgga aatttttatt taactgtcgt gtacgaagaa aagtttgcta taatggaaaa
    13861 aagcgtgcaa agaaagaggg agtttcatta tgatgctacg tgtagaaaaa ttgcgcaaaa
    13921 aaatgcaaga agaaaatttg gattcatttt tggttaccag tccgtacaat cttcgttact
    13981 taacgaactt tacaggtacg acaggattag ctgttattac tttggaaaaa gcatttttta
    14041 ttactgattt tcgttatacc gagcaggcgg cagcgcaggc tcaagggttt gaaattatta
    14101 aaaatgtcgg acctattttt gatgaggtag caaacttagt acgcaaagaa gaactgcact
    14161 cattagcttt tgaggaaaca acagtctcat ttttagaata ttcggtttta gaagaaatca
    14221 tcgatgcgga attagtacct gtttcacaga tgatcgaaga actcagagaa gtgaaagatg
    14281 aagaagaaat cgctattatc gaaaaagcat gtcatattgc ggatatggca tatgatcaca
    14341 tcctgaaaat gatccaaccg ggcatgactg agattgaagt cgcaaatcaa ctagactttt
    14401 atatgcgttc tcttggcgct tcaggtgttt cttttgatac gatcgttgct agcggattgc
    14461 gttcggctat gccgcatggt gtagcaagca aaaaaatcat cgaacaaggt gacttgatca
    14521 cattggactt tggttgctat tacgaagggt acgtttccga tatgacacgt acattcgcta
    14581 ttggtgatcc tggggaaaaa ttaaaagaaa tttatcaaat agtcttagat gctcaattag
    14641 cagttattga tgctgcaaaa ccaggaatga ctggtgtcca attagatgca gttgctagag
    14701 attatatttc aaaacatggt tacggggaag catttggaca ttctacagga catgggatcg
    14761 gtttagagat ccacgaagga ccaaacgttt cttctcgtgc agaaaagcaa tttgtaccag
    14821 gaaatgtgat cactgatgaa ccagggatct acttaccagg aatcggtgga gtacgtattg
    14881 aggatgactt gttgatcaca gaagatggaa atcgtgtgtt gactcgttca ccaaaagaat
    14941 tgatcatctt atagtttcat caatagaaga agtaagcgta aaaatcagtg ttcacagact
    15001 ttgttataga aaatcactcg atttaatgat acactataga agaactttta agctgtaaga
    15061 gataataaag ttgggtgttt tctccaattc atagcagttt gcagctgatc ggcggcagtt
    15121 ttcttaccac gtgatcacta tgccgcatca tagagaattc ggatgtatct cgtgcttagg
    15181 caaagggagg aataaataaa tggcagatga aaaaaatttg attttaaacg caaaccaaga
    15241 tttaggagag atcgtgatcg ctcctgaagt catcgaagta attatcggga ttgcagcttc
    15301 taaagtagaa ggcgtatacg gaatgcgcgg aacttttgcc agcaatgtca ctgaattatt
    15361 aggacgtgca gctcacggaa aaggtgttta cttagcaaac gaggaagatg gcttgaaagt
    15421 agatctttac tgttatctag aatatggtgt ttcagttcct aaagtagcaa tggaaatgca
    15481 ggaacgggtc agccagcaag tccttttcat gacggatatc gatttatctg aagtcaatat
    15541 ccatgtagta gctgttgttc ctgaaaaatt agaacaacca acaatcgaag aactttttga
    15601 agacgaagag gaagagaatg aataaagaat tatcaagaca cgagattcgg gaaatggcat
    15661 tgcaggcttt atttccatta gacttcaatg cagacctaac aaaagaagat gcgattttca
    15721 acgcaatcga attagaccac cgcgacatga tcaacgaaga tgaatcagag tttgttcctg
    15781 tttatcttga tacgctagtt ggcggtgtct gtgcaaaaaa agatgaattg gataaagtga
    15841 ttgaaaaaca tttaaaaaac aattggcaca tcaatcggat ctcaaaaatg gatttggtga
    15901 tcttgcgtat cgcgattttt gaaatgactt atgtgacaga tgtaccagcg gctgttgctt
    15961 taaatgaagc aatcgagttg gcaaaaacat ttagtgatga ccgttcacgt aaattcgtca
    16021 acggtgtttt atccaatgta ttgaaagaat tagaagctgg ggcgtaagtc ctagcttttt
    16081 tctatgaatc atcataaacc tgttataaat cgggaaaatt ctatggtaga atgaaaacac
    16141 aaaaaatatc tgggagtggt tagatggcag aattgattaa cggaaaagaa ttagctgaaa
    16201 aaatgcaggc agagattgct gaaaaaatcc aaaaattgaa agataatggt atccatcccg
    16261 gattagtcgt tttattggta ggggaaaatc cagccagcca aatctatgta agaaataaag
    16321 aacgtgtagc aaaagaaatc ggaatccatt cattggtaga gcgttatcct gagacgattt
    16381 ctgaagacga actacttgca gaaattgaaa aatacaatca agatcctagt tttcatggta
    16441 tattggtcca attaccattg ccaaagcata tagatgaaga aaagatcctg ttagctatcc
    16501 gccctgaaaa agacgtagac ggttttcatc cgatgaattt aggcagactc cttgcgggta
    16561 aaccggacaa gattccttgt actccatacg gcatcatgaa aatgtttgaa gcttattcta
    16621 tcgatccggc gggtaaacga gcagtagtta tcggacgaag caatatcgtc ggtaaaccga
    16681 tggctcagct actcttgatg gcagatgcaa ctgttactgt tgctcattct aaaaccgaaa
    16741 atctggctga actggcacaa gaagcagata ttttagtcgt agcaatagga cgtggacatt
    16801 ttgtcacaaa agaattcgta aaaccaggtg ctgtagtgat agatgtaggg atgaatcgtg
    16861 atgctaacgg taagctgatc ggtgatgtga aatttgatga agtggagcct attgcaggct
    16921 ggatcactcc tgtgccaaag ggtgtagggc caatgactat cacgatgctg atgtatcaaa
    16981 ccgtaaaatc tgccgaagct tttggagcag gtgaatagat ggcacaagaa tatttaactg
    17041 tcactacatt aacgaagtat ttgaaaagaa aatttgatgc cgatccttat ttagaacgcg
    17101 tatatttaac aggcgaaata tcgaatttcc gtttacgtgc caatgcccat caatatttca
    17161 gcttaaaaga tgaccatgca aaaatatctg ctattatgtt caaaggagca ttccaaaaat
    17221 tacgattcca gccaaaagaa ggaatgaaag tccttgtcgt tgggcgtatt tcattatatg
    17281 aagcgggagg ttcttatcaa atctatgtag agcacatgga gcctgatgga ataggtgctt
    17341 tatatcaaga attggaagaa cgaaaagaaa agctgatgaa ggaaggcctt tttcaagggc
    17401 ctaaaaaaat gctgccacgt ttcccaaagc gaatcgcggt ccttaccagt ccaagcggag
    17461 cggttatccg cgatatcatc acgacggtga aaagaagata tccaattgtc caattggttt
    17521 tgttcccaac agttgtacaa ggaaaccaag cagcggacaa tgttgtcagg aatatccaga
    17581 gagtagaaga gatgggcaat ttcgatacaa tgatcatcgg tcgtgggggt ggttcgattg
    17641 aggatttatg gccgtttaat gaagagcggg ttgctcgggc gatttatcaa gctaatacgc
    17701 cggtgatttc atctgtagga catgaaacag ataccacgat cgctgattta gtagcagatg
    17761 ttcgggctgc cactccaaca gcagctgcag aattagctgt tcctgttttg tcagaagagt
    17821 tgatgcgcat tcaagaacgg caagctagat tgcagcaggc gtttgtacgc cagatccagc
    17881 gcaaacaaga acggttcgag cgtgctcgac gttcctatgt atttcggcag cctgaaagat
    17941 tgtatgaagg tcagaccatc aaattagacc agttgaaaca gcgattatat caagctacac
    18001 agcaaattta tcatgcgaaa gaaaaacaaa cgatcgcatt aagccaccaa ttggaacaag
    18061 tggctccgct ttatcgagtt aaagcagctc gccaagaaac tgcttatcta gaaaaacgct
    18121 tagaagagaa aatccaacaa tatatgaaac aacagcagca gcgttttgct caagctgttc
    18181 aatctcttga tttgttgagt ccattgaaaa tcatgggaag aggctacagc tatacgacgt
    18241 taaatgatca agtagtaaaa agtgtcaccg agattcatca aggggatttg ctgacgatcc
    18301 attatcaaga tggaatcgtt aaaggacaag tacaagagat agacaaagga gaataaaaat
    18361 atggaaaatc caacttttga agagtcactg caagaattag aaaaaattgt catgcagtta
    18421 gaacaaggag acgttccatt agaatcagct ctagattcgt ttaaacgagg aatggaatta
    18481 agcaaacatt gccaagatac attagctaaa gcagaagaga ccttgacgaa aatgatgaca
    18541 gaatcaaatg aagaagttga ttttgacgga aacgaggaaa gctgagatga gattaactga
    18601 cttttcagct attcatctac ctgctgtaga aaaagaaatc ttgtcttttt tagatgagca
    18661 tacaacggat agaggactct atgatgcgat gagttattca gtgaaagcag gcgggaaaag
    18721 aatacgtccc ttattacttt taacggccgt tgcttccttt gatgagccta ttgatgttcc
    18781 cgtctatcaa gtagcagctg ctttagaaat ggtgcatacg tattccttga tccacgatga
    18841 tttgcctgcg atggacaatg atgatcttcg tagaggaaaa cctaccaatc ataaagtatt
    18901 cggcgaagca ttagctatat tggccggaga tggtttgctt acaggagcat tccagctaat
    18961 cagtatggca cacttaggta attctcctaa gcttctgctg cttcagcaat tagctgtttg
    19021 tgcgggatca caaggtatgg ttgctgggca agctgcagat atcgagggcg aatcgaaaaa
    19081 gctttcttta gaagaattag catttattca tgaaagaaag acagggcatt tgattcgtta
    19141 tgccttgctg gctggtggca tattagcgaa gcaacctgaa gaaatcttat tgctacttca
    19201 acgattagcc gaacatttag gtttagcttt tcagataaga gatgatctac tcgatgtgat
    19261 tggtacaacg aaaacattag ggaaaacagc tggtaaagat gaacgtatgg aaaaaaatac
    19321 ttacccgcgt ttattaggcc tagaaaagac acgtgaggcg ttggagattg agctgttatc
    19381 cgccaacaag atcatagaca aattagaaga ggacgttttt tcttttgatg gcgggctgat
    19441 gcgccagatg atcaagcaat ttgatgtgga gaaatgaggg aaagaatgga aaaagaacgc
    19501 gtagatgtat tagcggtcaa acaaggatta tttgaaacaa gagaacaagc caaacgttca
    19561 gtgatggctg gtttgattta caacgaaaaa aacgagcggt ttgataaacc gggagaaaaa
    19621 attccagtga gtagtgaatt aagagtcaaa ggtaaaaaac ttccttatgt ttctcgaggg
    19681 ggattaaaat tagaaaaagc actcaaagca tttgatctat ctgttgaagg aaaaacattg
    19741 ttagatattg gtgcatccac tggcggattt actgatgcag ctttgcaaaa tggcgcaaaa
    19801 atgagttatg ctttagacgt tggctacaat cagctagctt ggaaaataag acaagatcct
    19861 agagtcgtcg taatggaaag agtgaatttt cgttatgcaa aacccgaaga ctttacctta
    19921 ggaattccag aagttgctgt tatcgatgtt tcttttattt cactaaaact gatgctgcct
    19981 ccattacatg ctattttaaa agaagaggga gaagtgattg ctttaatcaa accccaattc
    20041 gaagcaggca gagaagctgt agggaaaaac ggaattgttc gtgaccctca gacccatcaa
    20101 aaagttttag aagacatttt gtcatttgcg gcacaaggtg gatatgatgt gctggaatta
    20161 agttattctc cgatcacggg gggagaagga aatatcgagt tcttggctca cttgaggaaa
    20221 gtacccgaaa gcggaacaat caattcagct attaatatgg cagaagtggt ttcaaatgca
    20281 cacgaacagt ttgaccataa ataaattgta actgtgaaaa tcaagtgaga agtatgcgga
    20341 ttcttcttta ttataccaag gaaataagct atcattgatt aagaagaata tgctaaggag
    20401 cgaagacgta atgagaaaaa aagatcggca tcgtttgatt actcgattgt tgagtgagca
    20461 agatatccga aagcaggaag aatttgttga aatcctgaaa agcaaaggaa tatctgttac
    20521 tcaagctacg atttccagag atataaagga actgaaactg atcaaggtac cggcttcaga
    20581 tggcggctac cgttatagca taccagctga aacaaacgaa gatgtaaata ctaaattgga
    20641 aaaactatta aaagacgctt tcgtggcagt tgaccaaatg gaaaaatttg ttattttgaa
    20701 aacattgccg ggaaatgctt cggcagcagc aaatttgatt gataaacgtt acaagaaaga
    20761 attattttcg attatcaatg atgacgataa tgttttgatg attacacgaa ctgaagacca
    20821 ggcagtttta ttgaagaaag acttcctgca ttacctttaa gttgaggagc gaatgtgatg
    20881 ctacaagaaa tcagtattac taactttgcg attattccgg aattgcggct ttcttttcac
    20941 gaaggaatga ccgcgctgac cggagagact ggtgcgggta aatccattat tatcgatgct
    21001 ttaggtctgt tagcaggagg aagaggttca agcgattata tacgtcaagg agcagaaaaa
    21061 tgtgtgcttg aagggttgtt tgaactacca aaacaagaag gattctctga actgatggtt
    21121 gaattaggga tcgaaacaga tgaggacaat ctgattgttc gacgggatat gtccttaact
    21181 ggaaaaaatg tttgtcgagt gaatggtcat attatcacat tagctaatct gagaagaatc
    21241 ggcagttatt tagtagatat ccaaggacaa aacgaacatc aggaactgct ccagcctgaa
    21301 tcacatcttg ctttattgga tcgttttgga gatgtagctt tccaacagaa gaaaaagagt
    21361 tatcagcaag aatatatctc ttatcgtgag ctggaaaaaa gggtacgaaa agtgcagcaa
    21421 aatgaaaaat cctatgttca gagaatagat atgctccatt tccagcaaga agaaatagct
    21481 gctgctgatt tgcaagtcgg agaagaagag aaattaaaag aagaaagaga aaaacttagc
    21541 aattatcaaa aaattgctga tggattagct gcaggttacg gagcactgac gaataatgaa
    21601 caaaacagtg tagatggtgt tggcttggcc gtttcagaac tgcaagggat cgcccatcta
    21661 gatgtggagt atgaagcaat ttatgaaaat atccaaagtg cttactattt gctgcaagat
    21721 gcaatcggcg atatgagtcg tcagattgat ttattggagt tagatgagag tcgtttagaa
    21781 gaagttacgc aacgtttaga attaatccga cagttgaaac gtaaatacgg cgaatccatt
    21841 gagtcaatat tggcttacta tgacgaaatc accgaagagc tagcttcttc tgatttttca
    21901 gaaggtcaat tggacaaaat gaaagaggaa ctagagcaaa aagagcttct acttcagcaa
    21961 caagccgcag atcttcatga agcgcgtaaa aaaatcgcaa aagaattgga aaaatccatt
    22021 ctgcatgaat tgaaaagtct gtatatggaa aacactgagt ttgaggtacg tttcttaaaa
    22081 gaagaaaata gacaattgaa tcatgatgga tttgaccaaa tcgaatttta cattacgacc
    22141 aatccaggag agccactgaa gcctttggtg aaagtcgctt ctggtggcga actgtctcgg
    22201 atgttgcttg ctttgaaaac tattttttct tctgagcaag gtgtgacaag tattattttt
    22261 gatgaagtgg atacaggtgt gagcggaaga gttgcacagg ccatcgcaga taaaatttct
    22321 caaatatcga aatactctca agttttgtgc atcactcatc tgcctcaagt tgctgcagtc
    22381 gccgactatc aatattatat tgtgaaagca gtgattgatg gacgtacgca aacttctgtt
    22441 tcagagttga aaacaaaaga aagagaagaa gaaattgcac gtatgctggc tggaagtgag
    22501 attacaaaac tcacactcga acatgcaaaa gaactattga aactcgcaaa aaggacctga
    22561 gccacctcgc agtggttcag gtccttttca gcagctgata gctatatttt atttttacat
    22621 gacactcatt acagcagtca atacaacaga tccaatcgtt aaaatcagca ttgtccaaat
    22681 gacaaatttt gttactttag caaaagtact tgtttgtttt ttttcacgca ttgttttcaa
    22741 cctcgtcatt aattagttga ttcaagtgta caatcttttt tccatttcca caagagggct
    22801 tttttataaa aacttccctt tttttaaata ataggtagtt acgatacaaa taaataatgt
    22861 taatagaact agccatataa aggcatcatc cctttcagca ataggtaact taatgttcat
    22921 tccatagata ctgccgacga ttgtcggtat agttaaaata atcgttaaag aagttaaaat
    22981 tttcataata ttattcagat tattcgatac gattgctgaa aaagtctgat tcatttgttc
    23041 tactagtttt aattgaatgc gagaagtagt cattgcctgc tctgtttcca ccaatacatc
    23101 acgtaaatga tttttcaaag catgattttc ttggaaaagt ttattttgcg ctagttcttt
    23161 caatgcatct aaattagcag aagtcgcttc tctgaaataa acgaggcttt tttggatatc
    23221 catgatttga taaagttgtt tgttttcagt ggatacttga agtttggctt ccaaagtatc
    23281 gcattgagat tgaagcgtag ctaaataact gttgtaagag agtgtgacct gccaaatgaa
    23341 ttgaaagaag atattgagat taggcgaaat atcacttttt ggaaaggtct ggctaaagac
    23401 tttctttaaa aacagtggtt catgattcgt aattgtgata agcttctttt tgggcgtcaa
    23461 aataatagag agcgggtatg tatccacttg aaaataaccg ctaggacttg ttttagcaaa
    23521 aggatattgt aacaataata acgctggctt tgtcaacttt gattgattga attcttctgt
    23581 acgggaattt tctgcatcgt ccaatatgga agtgatgtaa tctgacggaa tttcaaattg
    23641 atgtgtcagc tgatgaatct cttcttgatt aggacgttct acacaatacc agatcgtttg
    23701 gtcagtttcc tttccggtat tacgcagttt ctcattatct aatgtaaaat atttgatcat
    23761 gattttcctc ctgttgcctg tttcttttat tataacggat agggaattgg aatacatgga
    23821 atgtgtttgt aagatataga atataactgc ataaatttaa ataaaatgaa acagttgtgt
    23881 aaagtatata cagtatactt gaagcaacga taaaaaagga gtttacgttc atgggcacat
    23941 tcacaccact tatcttgttt tggtatattt acccggtaat cgttttgttt ggttgccaat
    24001 ttcttgtaaa attattttcg ttaaatcgtc gttttaaaat aaaagcccct gatttggcga
    24061 ttcctttttt gtggggcggt atgcatgcat tgtctagaaa tacagggaca atttctatct
    24121 taccgttttt ctttatttct gttttgctaa tgggaatttg tattgctgtt ttccaagcat
    24181 attattatga agaaattatt tatccgcgtt atttcaagat gacttggcgt ttggtttttc
    24241 tgttgacaat cgtcttgtac gctgtcttga tcattgtgaa catactttct tacctatgaa
    24301 aaaaatagaa aagctgtaaa aagtctttta aaaggctttt tgcagcttga tttttaaaaa
    24361 aatgtttatg aataaaaaaa gttgttcccg gatttcccag aaaaggtggt agaaagtggg
    24421 ggattgtggt agactaattt tagttagtgg aggaatgggg ggctttcaat gttgatgggt
    24481 gaattccaac ataatattga tgcaaaagga cgtttaatcg tgccctcaaa acttcgtgaa
    24541 gaacttggcg aaaagtttgt tctgacacgc ggattggatg gctgtctttt cggctatccg
    24601 atgagcgaat gggaaaatct ggaagctaaa ctgaacgaaa tgccgttggc taaaaaagac
    24661 gcacgtactt ttgtgcgatt cttctattcg gctgccactg aatgcgaact tgataaacaa
    24721 ggacgaatca atatacccag cacgttaaga aattatgcag ctttgacaaa aggttgcgta
    24781 gtcatcggtg tatctaaccg aattgaaatt tgggatgaga cacgatggca agatttttct
    24841 gcagcagcag aagagaactt tgacgaaatt gctgaaagta tgattgattt cggactataa
    24901 gaataggaag aggctgacta atgactgaaa catttcaaca ctatacagtc atgttgaaag
    24961 aaacggtaga tggattgaac atcaaaccgg atggcgttta tgtagactgt acactcggcg
    25021 gtgccggaca tagtgaatat ttattaagcc aactaagttc taaagggcat ctgtatgcgt
    25081 ttgaccaaga tcaaaaagca atcgatcacg ccaagctgcg tttagcttct tatgtcgaac
    25141 aaggtatggt cacatttatc aaagcgaact tcagagaatt agaagaacgc ttgagtgagc
    25201 atgtagataa ggtagacggc attttgtatg atctaggggt ttcctctcct cagctagatg
    25261 aagcagaacg tggatttagt tatcatcaag atgcaccgtt ggatatgcgc atggatcagt
    25321 cagctccttt atccgcttat cacgtaatta atgaatattc ctaccatgaa ttagtaaaga
    25381 ttttcttccg ctatggcgag gagaaatttt ccaaacaaat tgctcgtgaa atcgaacgag
    25441 tacgaaaaac aaaaccaatc caaacaactg gtgagcttgt cgaaatcatt aaacaagtca
    25501 tcccagctcc cgcaagaaga aaaggcgggc atcctgcaaa aagaattttt caagctgtgc
    25561 ggattgcagt aaatgacgaa ctcggtgccg aagaggcctc tttagaacag gcaatccggt
    25621 tattgaaagt caatggaaga atcagcgtaa tcacattcca ttcattggaa gacagaattg
    25681 tcaaaagtat gtttaaagaa tatagtacgg tacaagatct accaccggga cttcctgtca
    25741 tacctgacga attccaacca gaactgaaag tcattactcg taaaccaatc cttccttcag
    25801 aggaagagct aacagaaaac aatcgatcac gcagtgcaaa gttacgtatt gcagaaaaaa
    25861 taagaatgaa agaggagtag aatgatggca gaattaaaga aaatgcaaga ttacgaatat
    25921 gatttacctg aattggtgga tcagccggaa caacaaatgc ctgattcttc ttcgaatcaa
    25981 gaaatcattc ttccacaatc accggcaaaa cgattaaagc agatttctgc tttggaaaaa
    26041 attgctgtgg caagcgtggc gattgctatt gttgctttat gtgttttaac agttatgctg
    26101 cgcacaaata tcagcggagc tgaaaaagaa atcacgtcaa tacaaacaga aatcaatgat
    26161 aaaaagcaag aaaaaacgag tttagaacaa gaaaaaaacg aactttctcg tactgaacgg
    26221 attaaacaaa tcgcagaaga aaaaggattg tctattaatg acgacaattt aaggaaagtg
    26281 aagtaaatga gtcttaaaaa taaaattcgg cggtttatgg aaaagaaaaa tctaaatccg
    26341 atgaacaatc gcaaaaaagt aggtatcatt ttatttgcta cgagtattgg attgttcttt
    26401 ttatttgccg tccgtttctc gtatatcgtt attggaggtc atgttgctgg tacctcatta
    26461 gctgaaaaaa caaaacagtt gtaccaagga agtgaagtag taaaagcaaa aagaggaacg
    26521 atttatgatc gtaacggtgt ggcgctcgca gaagatgcct cctcttattc aattaaagcg
    26581 atactctcaa aaacatatac ctctggggat aaaaaactgt atgttgaaga aaagaatttt
    26641 gataaaatag cagaaatcct gcataagaat ctttctatag acaaaaaaga tgcactgaat
    26701 attttagagg acggcgcaaa aaaagagctg tatcaagttg aatttggtag ctatgggaaa
    26761 aatatctccc aagaaaccaa gcaaaacatc gaagcggaca tgaaaaaaga aggtgtcgct
    26821 ggtctttatt ttgtcgacca tcaggctcgg atgtatccaa atggcgtctt ttcttctcat
    26881 tttattggat acgcagttcc agacaaagat gagaatggct tagttggtaa actaggtttg
    26941 gagtctgctt acaatgatat cttgagcggt aaagatggta agattattta tcaaaaagat
    27001 aattttcaaa atcctctgcc aggtacagtg gcagaagaag aaaaagctgt cgacggacaa
    27061 gatatctaca cgactttaga cagcagacta caaagttatt tagaaacact gatggatcaa
    27121 gtaaatgaag aatatcagcc agaagaattg acagcagtcc tgatgaaagc aaaaaccgga
    27181 gaaatcttgg caatgggaca acgacctact ttcaatcctg aaacaatgga aggattgact
    27241 ggaaaagatg ctatctggcg taatttcttg gtacaagata gttatgaacc aggatcaacc
    27301 atgaaagttt tcactactgc agctgctatc gaagaaggag aattcaacga gaatgaaacc
    27361 ttccaatctg gaaaaatcca agtagaagat gctacgatca atgaccatga ctttggtgaa
    27421 aaaggtgtgc tgaccatgcg tcaagctctt tcatggtcaa gtaacgtcgg gatggtcata
    27481 ctggaacagc gattaggcgg acgatggtat aactatttac aaaaactggg atttggacaa
    27541 agtactcatt ctggattaga tgatgaagta aacggtgctt tacctacatt aaatattgtc
    27601 gaccgagcaa tgagtgctta tggacaagcg gtaggtgtga cgaatttcca aatgatgaaa
    27661 gctttcactt ctattgcgaa taacggtaca atgattcaac ctcgatatat cagcaaagtg
    27721 gtggatcccc aaactggaga agagcgaaca actcaaacag aagttctagg gcaacctttt
    27781 tcaaaagaaa caacagaaaa agtccgtgaa tatatgagag atgttgtcga aagcgaaaac
    27841 tacggtagtg cttatggtgt atatagtgta cctggataca atgtatcggc aaaaaacgga
    27901 acagcccaaa tcgcttctga tacaggggga tatcaaacag gagatacagc ctacctgtat
    27961 tcgattgtgg agatggttcc ttctgaagat ccagactatg tcttgtatct aacaatgaaa
    28021 caccctaaga catatgatcg aatggcattg gctaaaatcg caaatccatt gatgaaacgg
    28081 gcaatggatt ttaaagaaac tgaagaagat tcagatacag aaacaaaaac agaaaaagta
    28141 tccgtagccg attatcgtaa tcttgaagcg gacgttgcag cagctgatgc tcaaaaaagt
    28201 ggactgcaac ctgtagtgat cggtaatggt aaaaaagtac aaaaacaatc tactgccaac
    28261 ggtgatcagt tgatctctgg agaaaaactg atcctatata ctggtggtga taagctgatg
    28321 cctgacgtaa caggatggtc aaaagcagat atcatgaagc tggggaaaat cctcggtatt
    28381 gaagttagtt ttgatggaga tggttattgt gtcaaacaag aacttgctcc atatgaaaaa
    28441 atcactgaag acaaacttag ttttacttta gaagaataag aagagaaata ggagagaaaa
    28501 gagcatggaa tggacacaag cattgattcc cattgtcagc agttgtgcaa tgacaattgc
    28561 cgcaatgccg ctatttattg gttattttca aatgaaaaag caaggtcagg cgattcgtga
    28621 ggagggacca aagtggcaca atagcaaagc cggaactcct acaatgggcg gcttagtgtt
    28681 tctgatcggc tctattttga caggaatttg ggttggagct tggcaaaaac agctaactcc
    28741 tactcttttc atcttgcttt ttgtattagc gttatacgga gtaatcggct ttcttgatga
    28801 ttttataaaa atattcaaga aaagaaacat gggactgaac tcgaagcaga aattgattgg
    28861 acagattcta gggggaatca tcttttatct tgtttaccgt tctgaaggtt atccaggtgt
    28921 attgaatttc ttcggactag atctaccttt aggaatcatt tatggtattt tcgctctctt
    28981 ctggcttgtt ggattttcaa atgcagtaaa tctgacagat ggcatcgatg gattagttgc
    29041 tggcttagga agtatctctt ttgcagctta cggtctaatt gcttggcatc agcatcagta
    29101 tgatgtatta atcatttgct taagtgtttt aggaggttta ctgggtttct tcgtctacaa
    29161 cagaaaacct gccaagattt ttatgggaga tgtcggttca ttagcgttgg gcggactttt
    29221 agcggcaatt tctataatgc taaaccaaga atggacattg cttttgattg gtttgatcta
    29281 tgttatggaa acagcaagtg tgatgcttca agttacttcc tttaagctta caggaaaacg
    29341 aatttttaaa atgtctccaa ttcatcatca ctttgaaatg tgcggatggt cggagtggaa
    29401 gattgataca gttttttggt tgatcagcat tgtgacttcg ttgatcacat tatggatcgt
    29461 ttggtaggag atgacgggaa atgaaaaaaa tatcaacata tgaaaataag aaagtgcttg
    29521 tcttaggact cgcaaaaagc ggagtaagtg cggccaaatt attacatgaa ttgggcgcac
    29581 ttgtcaccgt taatgatgga aaaccttttg acgaaaatcc ggaagcacaa gagctgcttt
    29641 ctttagggat aaaagtaata acaggtagtc atccaatcga attgttggat gaagaatttt
    29701 cattgatggt caaaaatcca gggattccct acagtcatcc tttagtagca aaagcccaag
    29761 aaatgggtat tccggtaatt acggaagttg agctagctta cgaagtagcg gaatgcccaa
    29821 ttattgggat tacaggaacg aacggaaaaa caacgacaac aacgatgaca ggactactac
    29881 tgaatgcagg agcagatcaa ggaattgcac gtttagcggg taatattggg tatccagcaa
    29941 gtggtgtagc gcaagaagca aaatcagaag ataaaattgt gatggaattg tctagcttcc
    30001 aactcatggg aatcacagat ttccgccctc atatagcggt gattaccaat atctatgaag
    30061 cacatattga ttatcatggt acaagaaaag aatatgtcaa agctaaatgg aaccttcaaa
    30121 aaaacatgac agaaaaagat tatctgatcc ttaactggaa tcagtcagaa ctacaagaat
    30181 tagcgcaaag aacaaaagca cgcgtactgc ctttctcgac aaaagaagtg ttggaagacg
    30241 gtgtgtatgc tgacgattac tcaatatact ataaaaaaga aaaaataatg gaaatatctg
    30301 aacttggcgt accaggtaag cataatgtag aaaatgcact agctgctatt tctgtagcaa
    30361 aattgtatgg tatatcaaat gaagctatac gagaaacgtt gcattttttc catggcgtac
    30421 cacatcgtac gcaatatgta ggagaaatcc aaggcagaaa attttataat gattcaaaag
    30481 caaccaatat tttagcgact aaaatggctc taagtggatt tgaaacgtct aaggtcgtgt
    30541 tattggctgg cggattagac agaggaaata catttgatga attaattcct tcattaaaag
    30601 gaatcaaagc aatggtcgta tttggccaaa caaaagaaaa gttgatggat gctggaaaaa
    30661 aagcaggcat cgagacaata gtaacagccg attctgtaga acaagcagtt cctttagcat
    30721 tagaaaacag tacagatggt gatgtagttt tattatcacc agcgaatgcc agctgggatc
    30781 aatacccaaa ttttgaaact agaggaaaca gattcatgga agctgtgaac cgattaaaat
    30841 agaaaaagta gaagcgagcg ataaaaaatg aaaattttgg ttacaggcgg aggaacaggg
    30901 ggacatattt atccagctct tgcctttgtc aattatgtaa agactcaaga accgaatgct
    30961 gaattcatgt atgtgggagc aaaacgaggt ctagaaaaca aaatcgtccc tgatacagga
    31021 atgcctttcc ataccttgga gattcaagga tttaaacgaa aaatttccat gcataacatc
    31081 aagacggtcc gattgtttct taagagtatc cgtcaagcaa aaaaaatcct cagtgatttt
    31141 caaccagata tcgttatcgg tactggagga tatgtttccg gagcggtagt gtacgctgca
    31201 gccaaaatgg gtattccaac agttatccat gaacaaaaca gtgtaccagg tgttaccaat
    31261 aaatttttaa gccgatatgt ggatcggatc gctctttcat ttaaagatgc ggcttccttt
    31321 tttcctgaaa acaaagcagt tcttgtaggt aatcctcgag cacaagaagt agcagatact
    31381 aaaaaatcag atattttgaa aacatttgat ttggatccag aaaagaaaac agtcttgatt
    31441 tttggcggta gtcaaggagc acttaaaatc aatcaagcag tatcagtttt tttaagtgaa
    31501 tatattcctt cttcttacca agttttgtat gcttcaggag atagatatta tgaagagatc
    31561 ctaaataaaa taaatcctga aatacaaaat attagtgtcc agccttatat caaaaatatg
    31621 gcagaggtca tggcttccag tgatctgctg gtggggcgtg ctggtgcaac ttcgatcgca
    31681 gaattcacag ctctggggtt accggcagtg ttggttccca gcccatatgt tacgaatgat
    31741 catcagacta aaaatgcaat gagtcttgtt cacgcaggag cagcaaaaat gattgcagat
    31801 aatgaactaa caggtgaatc actaagtcag acagtcaacg aaatcatggg tgatgaagaa
    31861 ttgcaaaagc aaatgtgccg agcttctaaa gaacaaggaa tccctgatgc ttcaaaacgt
    31921 ctttatgact tagtaaaaca aataatcaaa aaataaaggc ggtggtctta gtgagtaaga
    31981 aaaaagaacc aaaaaaattg tctcatccgt cttctgatga aaacaatttg actccttggc
    32041 aaaaggctaa ccgaaaatat ctggcagaac aagagatgaa aaaccaagag ccaaaaaaag
    32101 aagacataac attagataca cccctttcag attctgaaga agaaaaaacg gttcaagagg
    32161 aacagcaaga agaaagccag tccgagaaaa aaatcgaatt ttttgaagag atcaagcaaa
    32221 agaaaaacgg tggaccatat aacggttctt ttttgaaccg gctgcccaat ttaaaaagtc
    32281 aacggcacaa agtactattt cgtcggttag ctttgatcat cactgtattg ggtataccgc
    32341 tgattttttt gatctattat gtttctcctt atagcaaatt acaagcagtt gcagtatcag
    32401 gcaataagac agtcaacagc caagaaatca tctctgatac aaaattgtca ttaggagaaa
    32461 atgtttgggg acagtatttt catcgatcta cttatatcga tcgccttaaa aaagcacagc
    32521 caagaatcga aacagcaaat atacatttca aagggatgaa tgaattcgat ttggatgtaa
    32581 cagaatataa agagattgct ttgatcgcaa aaaacaatca atactaccca gtgattgaaa
    32641 atggaacagt attagatgaa aaagtagcaa atcctacaaa aaatctccct atcttggaag
    32701 agttcaaaga ctctgcaaaa atcaaagaat taacaaagca atacaatcag ttatcatcag
    32761 aattacaaaa agcaatttct gaaatcaagt acacgccaag agcaagcaat aaaaatctga
    32821 tccaattgaa tatgaatgac ggcaatcaag ttattgtaaa tatcaataat cttgcgaacc
    32881 aaatgaaata ttattcgcaa gtagccaaag atatggatga aaaaggtgtg atcgacatgg
    32941 aagttggtat cttctcgcat ccttacggta gcactcaaga aacggaagaa tcgggccaat
    33001 cggaagaaac aactgaaagt gaagaaaatg cggatcaaac aaacgaatca agtgaagagg
    33061 cagaaacgca aaaagcacaa acacctggat cgtctagcac aaacggatca tctgattcaa
    33121 atgattcaag tgaaacaagt caaatagaag ataatccaag tacaactccg tcaagtttaa
    33181 atgaaaattg ataaaacaac tttaaaaagt aagaatgtac tttctaaaaa ccagtaattt
    33241 atggtagaat tggaagcagt gaatatatct attaataagt atattttaaa acggacgcta
    33301 gttgttcgct tgtatatgga atagtaagta ggagggaatc ccattcatgg caaaaacagg
    33361 aatgtatgta ggccttgata ttggaacgac atctgttaaa gttgtcgtgg ctgaatatat
    33421 cgacagccaa atgaatatta ttggagtagg aaacgcaaaa tcagaaggga ttaaccgagg
    33481 cattatcgtt gatatcgata aaacggtcca agcgatacaa cgagcagtac gacaagcaga
    33541 agaaaaagca ggtatccaga tcaaaggcgt aagtgtcggt ttgccagcaa acatgcttga
    33601 agtagaaaat tgccagggaa tgattgcagt taacggagat tcaaaggaaa tcaccgatga
    33661 agatgtcaga aatgtggctt cagctgccct tgttcgttca atacctcctg aacgtcaaat
    33721 cgtgtcaata ttgccacaag attttactgt cgatgggttc gagggaatca aagatcctcg
    33781 tggaatgatc ggcgtaagat tagaaatgta cggtctgttg tttacaggac ctaaaacgat
    33841 catccataac atacgtaaat gcgtggaaaa tgccggatta atcgtcaacg aaatggtgat
    33901 tactccttta gcgctgactg aatcaattct ttctgacgga gaaaaagatt ttggtacgat
    33961 cgtcattgat atgggtggcg gccaaacaac aacggctgtt atgcatgata agcaattgaa
    34021 gtttaccaat cttgaccaag aaggtggcga atttgtcact aaagatatct ctattgtatt
    34081 aaatacgtca tttaacaatg cagaagcgtt gaaaataaac tacggggatg catacccaga
    34141 acggacatca ccagatgaag aatttccagt agatgtgatt ggtcagtcag aaccagtgaa
    34201 agtcgatgaa cgctacttgt cagaaattat ttcagctcga atggaacaga ttttcaacaa
    34261 agcaaaagat gcattggacc aaatcgaagc attagagttg ccaggtggcg tcgtattgac
    34321 aggcggagct gctagtcttc ctggtgttgt ggacttggca caagaaatct tcggcgtaaa
    34381 tgtaaaattg tatgttccaa atcacatggg gctgagaaac ccggtattta caaatgtaat
    34441 aagtatcgtg gattattcag caaacttgag tgaagtgtat caattggcaa aaattgctgt
    34501 tacgggtgaa acctcagcag ctcgtcaaat ggtagttgaa caagaaacaa caaacacata
    34561 tgagagctat gaagcacctg aagaaacaat ctacgatgag ccggaaccaa aagagtccgg
    34621 agaaaatgta aaaaataaaa tcaagggttt ctttacaaat atttttgatt aattcatcct
    34681 gggaggaata agatatggaa ttctcaattg ataataatat caatgacggc gcagtaatca
    34741 aagtcatcgg agtcggtggt ggcggtggaa atgctgtaaa ccgaatgatt gaagaaaacg
    34801 ttaaaggtgt tgaattcatt acagccaaca cagacgtgca agcattaaaa aattcaaaag
    34861 ctgaaacagt tatccaatta ggccccaaat atactcgtgg tttaggtgct ggttctcagc
    34921 cagaagttgg acaaaaagcg gcagaagaaa gtgaacaatc cttacgcgaa gctttagacg
    34981 gtgcagatat gattttcatc actgcaggaa tgggtggagg aaccggtaca ggtgctgcac
    35041 caatcgttgc aggtatcgcg aaagaattgg gcgcattgac tgttggtgtc gtgacacgtc
    35101 cattcacttt tgaaggaccg aaacgtggcc gttttgctgc agaaggtatc gctcgtttga
    35161 aagaaaatgt ggatacatta ttaattatct caaataaccg tttattagaa gttgtagata
    35221 aaaagacacc gatgcttgaa gctttccgtg aagcagataa tgttttacga caaggtgtac
    35281 aaggtatctc tgatttgatc acagcgccag gttacgttaa ccttgacttt gctgacgtga
    35341 aaacagtgat ggaaaaccaa ggtacagcat tgatggggat cggtgtggct agtggagaag
    35401 atcgcgtagt agaagcaacg aaaaaagcaa tctcctctcc attgcttgaa acatctattg
    35461 atggagctga acaagtactt cttaacatca caggcggttt ggatatgaca ttgttcgaag
    35521 cacaagatgc ttcagatatc gtagcaaatg cagcaactgg cgatgtaaat atcattctag
    35581 gtacatctat caatgaagaa atgggcgatg aaatccgtgt gacggtcatc gcaacaggta
    35641 tcgatgaatc aaaaaaggaa cgcaagtcta gccgaccagc tagacaagca caaatgcaat
    35701 cacctgctca aaagactgta ttagatatgg atcaagctaa accaacttct tcagaagaag
    35761 aaaacagttt tggcgattgg gatatcagac gtgaacaaaa tgttcgtcct agagttgatg
    35821 attccaattt tgacaatatc gaaaaaaaag aatttgatac attcaaccgc gaagaaacaa
    35881 aatctcatgg cgatgatgaa ttaaatacgc caccgttttt ccgtcgtaaa aaataaagga
    35941 gaggaagagc acatgattgc tgacaacttg cagaaaatca agcaagaaat tcaggattcg
    36001 tgtgctcttg ttcatcgtga tccgaaagaa gttacattag tagctgtaac aaaatctgtt
    36061 gaatccgctc aagctgaaga attggttaga gctggcgtta tgaattgtgc agaaaaccga
    36121 gtagataaat tattagaaaa gaaacaagat ttatttgatt ttcctgaaat aaagtggcat
    36181 ttaattggta atttacagcg cagaaaggta aaattgattg taaatgaaat tgattacttt
    36241 catgcgttgg acagtttaag attagcagaa gaaatccaga agcggttaga gaaagaatta
    36301 tcctgtttta ttgaagtaaa tgtttctggt gaggaatcaa aacatggaat ttcaccagat
    36361 gagcttttac cgtttgtgga atctttagct gcctgcacaa aaatcaaggt tgttgggttg
    36421 atgactatgg cgcctaaaga agcttctgat gagcaaatcc ataaagtgtt tggtacgctg
    36481 aaagaattgc gtgatcttgt tcaagcaaaa ggttatgccc atgcaccatg tagtgaatta
    36541 agtatgggga tgagtcaaga ctttcaaatt gcgattgaag aaggtgcaac atttatccgt
    36601 gtaggaacag cgctattcaa agacgaataa aggaggaaca aaaatgccgc ttttaaacag
    36661 aggagcaatt gctaattttt tcggattagc tgatgaggaa gagtacgaat accaagatta
    36721 tcctgaaaca acaaaaaagg ctgtacagcc aactaaaaaa aatacaacac agaatcaatc
    36781 aactcattct gtatctgctg cgaatactca tgaaaaacaa aaaacggcga cttcacgtcc
    36841 tgtaacgcat gaaagtattc agccggctga aaagaaaaaa gtaattgaac tacatcaatc
    36901 acctacaaaa actgtagcga aagaaagaac agcttcaaga acctctacac aacctaaagc
    36961 aaatcttgct ggaaaaatca ctgtaatgga accaagagct tattctgaag ctatggcgat
    37021 tgctaaacga atcattgctg gagaagcaac cttagtgaat tttcatttag tagaagaaaa
    37081 acaagcgaga agaatcgttg attttctaac aggaacagtt tatgcactag atggagatat
    37141 caaacgtgtt ggagatgaga tttttctttg tacaccgact gggatggaga ttgacagttc
    37201 aaccgctcaa tcttttgcag atgcgaattt gtttgatctg taagaggagg aactacgatt
    37261 tatactattg cactattact tcatttactt caacgggcag cctatttcta tagcattatc
    37321 ttgatggtat atgcattgct ctcttggttt ccaggcgggt atcaatcagg gctaggacga
    37381 ttattagcta agatctgcga accgtatatc agtttgttcg atcgtctgcc tttgaggatt
    37441 ggacccttgg atttcacaat tttaggggca atcctgatct tgaacttagc cgtacaaggt
    37501 ttagcacaga tcgttatatg gataactgtc catttagttt attgattgaa gcaacaaaat
    37561 ctttattctc agaatagata ggaggggaaa attttggatg caaatgtata ccagcacttt
    37621 cgggcagatg aacgtacatt tatcgattcg gtaggcgatt ggattgaaca ggttcaagga
    37681 caatatgcac cctatctgac cgaatttctt gacccaagac aatcctatat tttagaaaca
    37741 ctgattcgac aaagcagtga tttgcgtttc atgttttatg gcggatatga acaggcagaa
    37801 agaaaaagat gtttgatttt ccccgattat tacgaacctg tagaggaaga ttttgaaaca
    37861 gcattgtatg aaatccatta tcctagcaaa tttgccagcc taagtcatgg gaaaatcctt
    37921 ggaactttag tgggaacggg gatcaaacgc tcttactttg gcgatatcat ctcggacggt
    37981 gatcgctggc aagtatttat tgcaaatgag gtggatcatt ttgttgctgc acaagtaaca
    38041 aagattggaa aggttgctgt acgcttggaa ccaatcaaat acacagaaat gattatgccg
    38101 aaagatagct ggacacaaga aagaggaaca gttagttcca tgcgactaga cagtgtgatc
    38161 tctgagattt ataatatttc cagacagcgg tccaagcagc tgatcgaagc tggtaaagta
    38221 aaagtgaact ggacagaaaa tacaagacct gattttgtac ttgaactatt agatattatt
    38281 tcagtcagag gttatggcag agtccagatc caagaacttg aggggaagac gaaaaaagaa
    38341 aagtacaggg tactgttcgg tgtattacgt aaataaaata aaaaggtggt ttactcatgg
    38401 ctttaactcc attagatatc caaaataaga cattcccgac aaaaatgcgg ggatataatc
    38461 aagacgaagt agatgatttc ttagatttag ttgttcgtga ctatgaggaa ttgactcaaa
    38521 gaaatcgaga attagaaaaa gcagtcaaac attctgaaga aaaacttgag tacttcaatg
    38581 aattaaaaga tgctttgaac caatcaatca tcgtagctca agatacggct gataaagtaa
    38641 aaacaagtgc aagcaaggaa tccgaagtga tcgttacttc tgcacaaaac aaagcagatg
    38701 agttagttgc gaacgctgaa aaacgtgcac atcaattaac aactgatgca gaagaaaaag
    38761 caagaaaaat cttgacagat gcaacagaaa aagcaagaca gcttgcgaca gaaactgaag
    38821 atcttaagaa aaaaacacga gtattccatc aacgtatcag cttgatgctt gagtctcaat
    38881 tagaacaagt gaaaagtccg gaatgggatg aaattttaca accattctcc agctacgtga
    38941 ctgacagcca tgaagtgatc aaagaagttt tagcaaaaca gcttgacaat gaaaatgata
    39001 ctgatgtaaa ctcagacaca ggagtcatag aagcacctat gacggcattt gatacacagg
    39061 ctattgatat ctcgatcgtg cctggtgaaa atgaaaacga gtagaacaga aaagcacttt
    39121 gttattctta aagcgagccg atgagagtgg aagttcggta agacactgca tggtgaaaga
    39181 tcctctactt gagacctgct tttccgaaat tagagtaaga agcagcggct gacctcgtta
    39241 ttggtcacag agagtttgca ctagatagat gcaactaaat ttgggtggta ccacggcatg
    39301 ttcgtccctt gcggctgaac atgctttttt gtgtccggaa aacaaataaa ggagtgtatg
    39361 gttgaatgaa aatgaaagaa accttgcaat taggaaaaac aaaattccct atgcgtggta
    39421 atttgccaaa ccgagaaggc gagtggcaaa aagaatggga agaaaatcga atctaccaaa
    39481 aaagacaaga gttgaacgaa ggaaaaccta gctttgttct tcatgatgga cctccatatg
    39541 ccaatggtaa tatccattta ggacattcat tgaataaaat cagtaaagac attatcattc
    39601 gttcaaaatc aatgtctggc tatcgtgcac catatgttcc aggatgggat acacatggat
    39661 tgccgattga acaagtattg gctaataaag gcgtgaaacg taaagaaatg tccatggcag
    39721 aatacttgga aaaatgtcgt gaatatgcac tttcccaagt agataagcaa cgagcagatt
    39781 tcaaacgcct aggagttgca ggagattggg aacatcctta tgttacatta gatccttctt
    39841 atgaagctgc acaagtacgc gtatttggta aaatggctga aaaaggctat atttacaaag
    39901 gattgaaacc aatttactgg tctccgtcaa gtgagtcttc tttagcggaa gctgaaattg
    39961 aatataaaga tgtaaaatct ccatctattt ttgtagcttt caatgtcaaa gacggcaaag
    40021 atattcttga tgaagataca gcttttgtca tttggacgac aacaccatgg acattgccag
    40081 caaaccaagg tattgctgta aatccaaaat ttacgtatgt attggtggaa gccgatggcc
    40141 gtaagtttgt cgtagcgaaa gatttgctag aaacagtcca atcagaaatc ggttgggaaa
    40201 atgtaacagt tctaaaagaa tttgctggac aagaaatgga atatatgact gcaagtcatc
    40261 cattctatga acgtgaatca cttgtgattt taggcgatca tgttacttta gacgctggta
    40321 ctggattagt ccatactgct ccaggacatg gggaagatga ctatatcgct ggtagcaaat
    40381 ataaactatc tgtagtgtca cctgtagact caaaaggatt gtttacagaa gaagcacctg
    40441 gatttgaagg tatcttttat gacaaagcaa atcctatgat cactgatcta ttaaaagaaa
    40501 aaggagcttt gctgaagcta gatttcttta ctcatagtta tcctcacgat tggcggacga
    40561 aaaagcctgt gatctatcgg gcaactccac aatggtttgc atctatcgat aaattccgtc
    40621 agaatatttt ggatgaagta gaaaaagtag agtgggttat cccatggggt aaaacacgtt
    40681 tgtataatat gatccgtgac cgcggcgatt gggtaatttc ccgtcagcgt gcatggggag
    40741 taccacttcc gattttctat gctgaaaatg gagaagcaat catcacacca gaaacaatcg
    40801 aacatgtggc aaaattattt gctgaacatg gatcaattat ctggtttgaa aaagaagcga
    40861 aagaacttct tcctgaagga tttacccacc caggttctcc taatggcgaa tttacaaaag
    40921 aaaaagatat catggatgtc tggtttgatt ctggttcttc tcatgaagct gttttacgtc
    40981 agcgaccaga attatcattc ccagcagata tgtatttaga aggatcagac caatatcgtg
    41041 gctggttcaa ctcaagtatc acgactagtg tggctatcaa tggtgtagca ccatacaaat
    41101 cagttatttc tcaaggattt gctttagatg gtgaaggccg taagatgagt aaatctttag
    41161 gaaacatcat tgcaccagaa aaagtgatca aacaatttgg tgcagatatc cttcgcttat
    41221 gggtatctag tgtagattat gaagcagatg ttcgtgtttc tatggatatc ttaagtcaag
    41281 tggcagaagt atatcgtaaa atcagaaata cgatgcgttt cttattagcg aatacagaag
    41341 atttcgatcc taaaaaagat actgtttcgt acaatgattt acgttctgta gacaaatata
    41401 tgaccgttcg attgaaccaa gtaatcaaag aaatccgaga agaagggtac gacaaatata
    41461 acttcatgca tatttaccgt acagttatga acttcttgac ggttgatcta tcgtcattct
    41521 acctggattt tgctaaagat gtagtttata ttgaagcaga agatgattat caacgtcgtt
    41581 gcatgcaaac tgttttctat caaacagctg tagctttgac aaaattattg actcctatca
    41641 ttccgcatac agcagaagaa atctggtcat tcctgaaaga agaagaggag tacgttcagt
    41701 taagcgagtt tcctggttat gaagagtttg caaaccaaga agaattgatg gatacctgga
    41761 ctgctttcat ggacttccgt gataatgtct taaaagcatt ggaagaagca agaaacagca
    41821 aattgattgg taaatctttg gaagcaaaac taactgttta tccaaaacaa caagttcgtg
    41881 aaatgttaaa agctttggat gcagatattg cacaattatt gatcgtttca ccagactact
    41941 ttgaagttat ggcagcagat gaacaagtgc cagataacgc tatggtattt gatgatgttg
    42001 ctattacagt ggaaaaagca gacggggaaa cttgcgatcg ctgtcgccaa gttcgtaaag
    42061 atgtaggagt agatgaaaaa cttcctcatc tatgcggtcg ttgtgcaaaa atcgttgaag
    42121 acttctatcc tgaagctgta gctgaaggat tcgaagaaaa gtaaaaggga aaagggggtg
    42181 tgacatgttc tttgtcacac ccccttttgt tatcaatcgt ttaattttcc acgttcacga
    42241 taccagttat ctggttgcca gatccattcg aatccgtctt tttcaagtag ttcgaaagct
    42301 gctttaggtc ccattgatcc agctttgtag ttgggaaaat ccggttgtgt ttggtcccaa
    42361 gcttttcgaa tgacatccac gatatgccaa gattgagcga cttcttccca atgagagaag
    42421 ttcgttccat caccattcaa cgcatctaat agtaattttt cgtaagcttc tgggctattt
    42481 tcaaccattt ctgcactatt tctaaattcc aatttgattg gttccgtttc aaatccttgc
    42541 cctacttctt tcccattcaa ggataaagaa aatccttcag ttggctgaat atagatcgtt
    42601 agaacattag gtggaagtgt cgtatcgtca catggttcat cgacagatgt tttgaataca
    42661 ttaacaggaa cttgtttgaa tacgatgttg atccgagtcc ctttttcagt caaacgtttg
    42721 cctgtacgta catagaaagg aacacctgac caacggaagt tatcgatagt gaatttgcct
    42781 gcgacgaatg tttcagtctc tgattgagca tccactttgt cttcttcgcg atagcccttg
    42841 aattgtacac catccaattc accttgagca tattgcccgc gaacgaagtt ttctaacact
    42901 tcttcttcgt tataaatgcg gatagctttc aatgctttga tcttttctgt acggatttct
    42961 ttttcggaaa atgctactgg cggttccatt gcaagtaatg ctacaacctg taaaatatga
    43021 ttttgcacca tgtctttaag tgcgccacta tgatcgtagt agcccccgcg atcttctaca
    43081 ccgaggtttt cgccaaaagt aatttggata ttgtcgatat agcgattgtt ccattgagcc
    43141 tcaaaaatat tattggcaaa acggatagct gagatgtttt ggatcatttc ttttcctaaa
    43201 taatgatcaa tcctgaaaat atcttgttct gggaatactt ctctgatttg ctggttcaat
    43261 tcaaaagcag actggtaatc agaaccgaac ggtttttcta tgatcaaacg attgaagcca
    43321 ttttttgtca taatattttg tgatttcaaa tgagaaacga tcgttccaaa aaattgaggt
    43381 gccatagcca aataatagac acggttaccg tttaattgat agtgtccatc taatcggtca
    43441 gacaattctt ttaatgtctg ataatgcgtt gaatcattta catcatggga ttgatagtaa
    43501 aaatggcttg caaaggtagt tgcttcttca tctgaaggat tcaatgcacg gattgtttct
    43561 ttgacaactt cacggtagtg ctcatcgctc cagggacggc gagcggttcc gattacagca
    43621 aaatgctcgc ctaaatttcc ttttctgtaa aggcggaaca aagacgggta caatttacgc
    43681 tgggctaggt cacctgtacc gccgaatatc gtaaacaata catttttttc attagacatg
    43741 tggatacact cctttatatt ttatcgacaa aaatcgtgct ggccgcctta aagctgacgg
    43801 ggattttctt tctatcattt tggatagtga tcggtccttc ataagctgcg atgtcaacga
    43861 tctcatattc ttcgttgata ttcaggtcaa tagtgactaa gtaatccaac aattcttttt
    43921 catcaagcac tcgtgcgata cgcacttttg taccgacagg ataggactcc aatgtttgtc
    43981 ggcgttcttc atggacaact tcctcttttt taggaatcga tcctccatga ggacaatgtt
    44041 caggatgatt caaatagttt tctaaatgat ctgcaagatg ttccgaagtc acatgttcca
    44101 atacttcagc atcatcatgg acttcattcc agctatagtc taaatgttca actaaaaaaa
    44161 cttcccataa gcgatgtttg cgaatcagac tgctagcttt ttgcagtccg cttgcagtca
    44221 attgtacacc ttgataaggg gaatgttcta caagctcttc tttcacaagt ttagaaatca
    44281 tttcactgac agatgcagct gagacatcta gactagatac gatttgttta ttgttgactt
    44341 tcgttgtatc tccacctagt tctaaaatga ttttcaaata atcttctcga tttggtgtca
    44401 tattcgatca tcctttcatg gtaaaaaacc atcattagta agtgtaacaa aaaaaacgtt
    44461 aattgactat ttttctaaat aaaaaacaaa ggatttttag acgtttttac aacaaaaaac
    44521 gaaagatgat agagaagact cattctttcg tttataaagg atatatatat acattgggag
    44581 ggatctattt ttcagataac aacttatatg aagtgtctgc agattcgtca taaagagttt
    44641 gttcgggata agaaaagata agataaaaac catactgatc acgtacgact aaacgatatt
    44701 catctatttc taccacagat gtgccaagag actgaccgtt gatcaaaaac gtgtaatcag
    44761 atgtaatctg taattgttgt ttttgctggc tatcactaaa gaaccatgta ccttgatact
    44821 ttgagagtcc ttctgacttt tccgcttgtt ttttcttttt caagtaaata aaacttgaga
    44881 gaacggtaat gagtgaacca agaaaataga tcattttttt tatcaccaaa tcactccttt
    44941 atgagaaaat aatcgcatag acatattctt tcttctttat ttcattgtac cgaataaaag
    45001 ctaaaatttc tctaagactt tcgactggtt tttttactgt ttttctacaa attatgatag
    45061 gatacatagt aggaagaaag gtgacataat ttgaagtatc agcaagtgga aatagctttt
    45121 tttattgacc gcccgaatcg gtttatagca cattgtatga aaaaagacgg agaaataatt
    45181 attgcgcatg tcaaaaatac aggtagagga aaagaggtcc tgataccagg cgctgaagtg
    45241 gctattgtat ttgctcctgg acctaaacgg aaaaccgcct atgatctgat tgctgtaaaa
    45301 aagaagggtg actggtttaa tatcgatagt caattgccta atcggctggc aattgatggt
    45361 attttagacg gcacgatcct tttaccagga ttaactggtc catttacggt atacaagcgt
    45421 gaagtaactt atcttcactc caaatttgat atttatttag agacggtggt cggacaaaaa
    45481 gcatttgttg aagtcaaagg tatgacactt gaaaataaag cgattggtgc ttttcctgat
    45541 gcgcccacac tcagaggatt gaaacatata ggagaattaa cgtatgccgc acaagatggt
    45601 tatgccgctt atgtcttgtt tattgctcag ttcgaacatc ttcatctggc aacgatccat
    45661 gaagaaatgc aaccagcact agctgatatg gttcgacatg cgcagcaaag cggagttcaa
    45721 atcctcgcct ataattgtca agtatcggca gatgaggtaa ctgtcaagca ggccattcca
    45781 tttgatgtag atatcccttt tgaagatcct atacaataga aagaaggtaa aataatgatc
    45841 aacttaggta ttatcggaac aaattggatt actcatcaat ttgtccaagc agctttaagc
    45901 acaaaaaaat atgaattgac agcggtatat tctagacatt tggaaaaagc acaggaattt
    45961 ggttctcatt atgaagggga tatcgaattc gcaacagatt tgaagacttt tttcaatatt
    46021 actcatatgg acaccattta tattgcttct ccgaatagtc ttcactttag tcaagctaag
    46081 caagcaattt tggcaggaaa aaatgtgata gttgaaaagc cagctttttc gacgccaaaa
    46141 gaaatggatg aaatcatcca tttggcaaat gaacacaatg tgtatttttt tgaagcagca
    46201 agaaatatcc atgaatcagg ttttaaaaag attgccgatt acttaccatt aaaagacgag
    46261 ataatcggtg caaatttcag ctatatgaaa tattcttcgc gctatgacca agtattagat
    46321 ggagaagaac cgaatatctt ctcgactcat ttctcaggtg gtgcattgat ggatttaggt
    46381 gtttaccttg tatatgcagc tgttgcttgg tttggaatgc caaaagaagt ccattatttc
    46441 ccaagaaaga tttctactgg tgtagatggt cttggatggg ggatcttacg ttatgagaat
    46501 tttgatgtat cgatccagcc aggtaaaatc ggtgattctt atttaccgtc agagatttat
    46561 tttgactcag gaacgctagt gatgaatgga gtcaatgcaa ttgaacaagc acaatttcat
    46621 gatcgcgcgc ataaagaaat cattgatttg gcggtaacag ctgcagaaaa tccaatggca
    46681 gatgaagcag aggattttgc caatgtcatg gctcatccga aagatccagc ttggggattg
    46741 ttgtatgaag agtggatcga gctagctaga aatgtgaacc aagtgattta tgatttaaga
    46801 aaaaatggcg gcatcaaatt cgatgcagat aatgaggaag atttttaatg aacgaatttg
    46861 tacaagtatt tcccgaaaat tggcagaaaa aatatgagga taaagggttt atctcacctt
    46921 ctcttattca acgagcagtt tttcagccac taagtaataa acaaagtata gtagcggttt
    46981 ctcctacagg ttcaggtaaa acactggctt atctttggcc tctactacta aacgtggaac
    47041 caggtgaagc aagtgcgttg gtcatttttg cttcttctca agaactagct attcaagtag
    47101 cagatgttgc acgtgaatgg ggaaaagaca aagagttgaa agtccaatct ttggtgggcg
    47161 gagccaacgt caaacgtcag attgagggtt tgaaggaaaa accagaaatc ttgattggta
    47221 caccaggaag aatattggaa ttgatgaaag caaaaaaaat aaaagcacat caagtgaaaa
    47281 caatggtatt tgatgaagca gaccagctat ttgacgctgg gaacagccaa atcattgatc
    47341 aaattcttca tcaagctcca acagagtatc agctagcttt tttttcagcg acagcagatc
    47401 gttcccttga aagcattgaa aaaatcactg ggaaaacgtt tgagacaatt gacgtgacag
    47461 cagaggacga ttctcgaaaa ggactgagac attacttttt acgtgtaccg atacgaaaga
    47521 aagatgacta cttgagacgt ctcacgcata tagaagattt tcatggtctg attttcttta
    47581 atcaactgac tgaattaggc gtaatggaag aaaaattgct gtatagaggt gtaccggtag
    47641 gaagtctggc ctctgatcag aacaagctac tccgaaaagc agcgctagaa caattcaaaa
    47701 agaaaatggt cagagcactt ttgaccacag atgtggcggc tagaggttta gatattacag
    47761 gtcttcctta tgtagtgaat gcagaagttc cgttaagtga agaagcttat ttgcatcgtt
    47821 cgggaagaac tggtcgaatg ggtaatgaag gaatagtaat tacactcgta caagataata
    47881 atctaagaga tttaaaacgg cttttacgtc catcaaatat aacacttgaa gagatttttt
    47941 tatacggagg taagctgcaa actgagcagc caaccaaaga agatgcagct cctgcagtaa
    48001 ataaaaagta tgcgaaaact ttttctggaa aggagcagaa cccagaatat aacaaagaaa
    48061 aaataagaaa aaaagttaaa aataaatcaa aaaaagagag aaataaagga gcaaggcgca
    48121 aataagcgcc tttttatgct atgattatga aaacgggaac aaaattggtt gccagaggag
    48181 gggttatgtg aaagaacgtc aagaagagat cttgcagcta ttgacagaaa accaacaagg
    48241 attgacagca agtgatgtag ctgagcgctt aactatcgat cgaagcaatg caagccgata
    48301 tttaagtgaa ctatacaagg cccatcatat tgtaaaaacc gctggccgac cagtcgttta
    48361 ctctttgcca acggaaaagt caaaatctga tgaagtgcat gtcgactctt ctacgcaagt
    48421 gacttttgaa acactcgttg gagaaaatga ttctttaaaa gtcagcatac agcaggcaaa
    48481 agctgcgatt ctttatccac cgcgggggtt gcatacgatt atttttggag aaactggtac
    48541 agggaagtcg atgtttgctg aatgtatgta tcattttgca atcgattcag agatgctttc
    48601 tgcagatgcg ccatttgttt ctttcaattg tgcggattat gctcaaaatc cgcaactgct
    48661 ctttggacac atctttggga tcaaaaaagg ggcttacaca ggagcagctc aagatagtcc
    48721 cggtctaata gccaaagcag acggcggtat attgttttta gatgagatcc accgtttacc
    48781 gccggaaggg caggaaatgc tgtttacttt cattgataaa ggtatttacc gtccgcttgg
    48841 agaaagtgca caagtacatg aagcatctgt tcagatcatt ggggcgacga ctgaatcttc
    48901 agaaagtttc ttatctacgt tcaatcgacg gattcctatg gcaatcacct tgccgaatct
    48961 tgcttcacgt tcactggatg agcgttatga aatcatctct ctttttatca aacaagaagc
    49021 gaatcgtttg aatcaacgta tcgatatcga aaaagaagcg attcttgcct tcatgcttta
    49081 tgatgcggaa ggaaatatcg gtcaagtgaa acgagacttg aaactagtct gtgcaaaatc
    49141 ttttttacat taccgtactc atcatgagaa aaagctaatc attcgaaaag aagaactttc
    49201 ccttcaagta caaaaaggat tactgaaaat caaggaaata ccggaacgtc tcgaccgatt
    49261 catggacagc aaaagtcagt atttgacatt tgaaccagga tttgctgatg ttgtctggtc
    49321 acaagatcca gaacgaaaca tgcaggtcta taacgatatt gaggaaaaag tcacttctct
    49381 ttccgaaacc ggtgtggaga acattgatct agagaccctc atttcaaaag atgtggatgc
    49441 ttatttccag acatatgtca aagaattgac taaaagttcg attcccaaag atcttttgcc
    49501 agatgaaatc tggcggttaa ccaatcaatt gtatgatgtg gctgaaaaac ggttagaccg
    49561 tatttataat gaaaaagctc gttttgcttt tgctttgcat ctgcaaagta cattggatcg
    49621 tgtgagagaa ggtcatatga tcgtccaccc agatttgaat aacgtacgga aaaattttaa
    49681 gagggaattc caggtagcaa tcgatctttc aacgatcatt gaagaagaag aacaagttga
    49741 gattcctttt gatgaaatcg gctttattag tatgtttctt tctatcaatc taggagaaag
    49801 tgagcctgtt aaagaaaaca aagtagatgt tctcatattg atgcacggca gacagactgc
    49861 ttcaagcatg ttggagatgg cacaagaact attaggaaca aaagtaggga aagcttttaa
    49921 tatgccactg gttatggaag ttcaaacaat gtatgaagaa gtgttacaat atgtcaaaaa
    49981 ctatcaagag catttgacga atggcctact cttgttaaca gatatgggat cattaaacac
    50041 cttcagtgat ttgatttatg aagagactgg cattcggacg aaagctatca cgatgacaag
    50101 taccatgatt gtgatagaag cgatacggat ggcaagtgtt ggaagaagct tagaagatat
    50161 ttatcaaaat atccagcttt cctttgaatc gatcgtacgt gatcagttca aagcggaaaa
    50221 gtctgaaact ttacagcgta aaaaagccgt aatcgtgaca tgctttactg gtgaaggagt
    50281 agctgccaaa ttatatcagc gtattatgcc agtgattaat caaaataagg tagaactgat
    50341 ccagatgcag tttttagaac gtgaatcatt caaaaaacac atcgatgcct tattggaaga
    50401 atatgagatc aaagcaattg cgggaacagt tgatgttgat tatcaaaata tcccattttt
    50461 ttcagcctat gacgtttttg atgatgaaaa actaaatatt ttaaagcgta tagctgatga
    50521 tgagatcccg acagctaaaa ttgtcgattc acttgctgga tcattaagcg atgtcttttc
    50581 tattgatgaa ctgatccgtt cattgcaaaa gacagttcag cagatccaga ccgatttgtc
    50641 gattatcgtg gaacctggag tagatactgg aatcgttatc catttagcct tcatgttaga
    50701 cggattgatc aaacaagaaa gccatcggca atttgagaaa ctgtctattt tctcaaaaat
    50761 ttatcgtttg gaaatggata tcgttcgggc aaacttgatg gcactagaac gaaaatatca
    50821 ggtaaaaatt ccagaagatg atatcgcatt tcttacacaa atgtttcttg aaaataaaat
    50881 aaaaaaatga acacactaat catactgttt acacactaaa catctgtgtg cgcactataa
    50941 aaaagagcta aaaagcatga aaacgctatt tcagctcttt tttttattgg catgcttctt
    51001 gcgttatata aaagtgtaaa aaaataaaag gagtgttaaa aatggcaaaa aaaacaatca
    51061 tgttagtttg ttcagcaggg atgagtacga gtttattggt cacaaaaatg caaaaagcag
    51121 cagaagaaaa agggatggaa gccgatattt ttgcggtctc tgcctcagat gcagataata
    51181 atttagaatc taagaatgtc gatgtattat tattaggtcc tcaagtacgt ttcatgaaag
    51241 ctcaatttga acaaaaactt gcgcctaaag gtattccatt agatgtcatc aatatgcaag
    51301 actatggcat gatgaacgga gaaaaagttc ttgcacaagc agaaaatcta atgaaataaa
    51361 tcaagtatgc agttgggggt ataacaacgt ggaagatcaa caaaatctag aagccatcat
    51421 ggggttaatc atgtttggcg gtaatgcaaa gagcgatgca atggaagcga ttgcggctgc
    51481 taaaatcggt gattttgagt tagcggatag gaaaatcgct gatgcagaag aatcacttat
    51541 acaagcgcat catgcacaaa cagacatgtt gacacaagaa gcacaaggaa atcatatgca
    51601 agtgacatta ttgactgttc acagtcaaga tcacttaatg acatctattg cgtttactga
    51661 tttagcaaaa gaaatcatcg aactttatcg tcgcgtatac agcgaataaa tacaacttct
    51721 tttttgaacg gaagaagaaa aatttttgaa cggatttttt attttgttat aaggagaact
    51781 ctctttatat aaaaaactta taggaggaag taaaaaatga acggactatc aagttggatg
    51841 gagaaataca tcctgccggt tgccgcaaaa atcggagcgc aaaaacattt agttgctttg
    51901 cgtgatgctt ttatcggcac actgcccgca acaatggcgg gatcagtcgc tgtaatgatc
    51961 aatgcaatta ttcgtgattt accgcaacag tttaacagta cctatgctga cagtttagca
    52021 gcagacaaag gaatctttgc cgtattgaat gtcatcatcg gaatcaatgg ttttgtctgg
    52081 aacggtacac tagcaatcgc cggattgatc tttgcctttt cttgggggta taatcttgcc
    52141 cgagcttatg gagtaaatga tctagctggg gggatcgttg gtttagctac cttgattcaa
    52201 ggtatttcct ttggtccagc attatcagca gcattagatg tgaatgttcc ttcaaatgtc
    52261 gcagatgcaa tcaatagttc tgagattggt gcaacgattg cagatggcac actgtcagtt
    52321 ggattatggg gttggctaaa actagatcat ttgaatggaa acgcttattt tacagttatg
    52381 atcatgggag ctatttcagt cattattttt tgtaaattga tgcttgccaa cattacgatc
    52441 aaaatgcctg attcagtacc accagcagta tctaaagcat ttgcagccat tttaccagcg
    52501 acgatcgctt tatacgtcat tgctattatc aattatatcg taggtcgtgt agctgatggg
    52561 caactgatca ttgatttggt gcaaaaatat attgcagagc cattcctagg attatctcaa
    52621 gggttgggag cagtattgat cgtcacagta tttgttcaag tattctggtt ctttggtatt
    52681 catggaccaa atgtattggc accagtgcta gagggaatct ggggacaagc acaactaatc
    52741 aatattgata ttttccaaaa aggttataac ggaaaaactg gtacaccagc cgtgttagat
    52801 gcaatcgaag atggaaaagc ttatatgtgg gtccgcggat cgttcgatgc ttttgcatgg
    52861 tttggcggat caggcggaac gatcgtctta ctgatagcta tcttgatttt ctctaaacgt
    52921 gcagattatc taacagtagc taaattatcc attgggcctg gtatcttcaa tatcaacgaa
    52981 ccagtgatgt ttggtctgcc aatcgtattg aatgcaatca tgtttatccc attcttgatt
    53041 gctccagtag tagcaacagc aattggatgg acagctactt atcttggcct agtcgctccg
    53101 gtatcgcagc aagtcacatg ggtagtaccg ccgttcttat tgtcattctt agcaacagga
    53161 gcggattggc gggcaccgat cgtaacatta gtatgtatgg tcgtgacttt cttgatttgg
    53221 gcaccatttg tcatctctgc aaacaaaatg gaccctgccg caggcgcgaa caacaataag
    53281 atgaacgtga ggagcgggac gctttaagtt tcgttcctca taatgaattt tcgaggagga
    53341 actgaaatga ttacaattgc cagtgcaatg caacaagatg aaatcaaaga attgttagaa
    53401 ggatacaatg aagaaggaat gacttttaca tttaaagaaa aacaaggaat caagctgttc
    53461 tttgaaacaa gtgcagaaga tccggaagtt gcggctaaaa aagcaaagga actaatcaaa
    53521 gcacagcctt ggggaacagt cctttatttt caatcaacag ctgtttagaa aatggtttaa
    53581 aaagatagga tggttgagat gataaaaaac ggtttatttt tatgtagtat tggttctttg
    53641 atcgtgttgt atagtttgaa tccacattcg caaaggtatg atttgtatag tatggtcaca
    53701 ggtctttttc taacaggatt aggaatctat ttcttcatga aggggaaaaa aagagaagaa
    53761 gcaaaggaga aaaataacta atggaaatca cgaaaaaatt aaatattcca gcatcgtttt
    53821 tttacgataa agttatggac tctgtccttt tcgatgtacg taaagcgacc ggcaaatcag
    53881 taactagaaa acagctgaaa aatttggagt acgtcaaaca attctcgcaa aataaccggg
    53941 ctcgcataaa aatcgaagaa gtcattgaaa accagtctta taagtttcgt acatcgacaa
    54001 cgaagaatga attcgtcgtt cattatcaaa tcaaaccatt ggacgattcg acctgtgagg
    54061 ttcattacac agaaaaaatg gagtcttatg gcatgcttca aaagttgaat gatatgcttt
    54121 taggaacaat cttgatgtat tttaaacgga gacgtttcaa aaaaatgcta gatatgatcg
    54181 aagcaacgta ttaaatcaat gaaacatggt actatttagt tattgaaaaa tgaagtaagc
    54241 tagaaggaat ttttcatagg aagatagatc tttcctgcga atcctcacta gcttttttgt
    54301 aggaaggggc agcaaaatga caaacaaagt aagagagcta ggtgtatctt cgattgagga
    54361 aatgtttgat ttagccactt atgcatttaa tggggcagat acacctgaaa ggcgagaacg
    54421 ttttcgtaca cttgcggaga attcttggaa ttacggattt tttgatgagg aggatcggct
    54481 aacaagtcaa gtcatggcga ccccttttcc agtgaatttt tacggacaag agtacctaat
    54541 ggccggcatt ggctatgttg cttcttatcc agaagcaagg ggacaaggcg ggatcaatca
    54601 gatcatggaa aagatccttg aagattgccg tgatcgtaaa gtaagcttat cttatctggc
    54661 gccattctcc tatcccttct atcggcgcta tggctatgaa caatcatttg ataaaatcag
    54721 ttatcaacta aacagtcgtg atgtgccgtt tatcaaaaaa aaatctggaa aaataaagcg
    54781 tatggatttt gaagatgcaa aagctgcaat cagaagaatt tatgaacaga tgccggaaaa
    54841 ccaacgagct ggtctgaagc gcgaagactg gtggtatacg tataaattca agcaaaaagg
    54901 caattaccag tttgctttgc attttgatga taatgaggaa gcaacgggat atatcgttta
    54961 tcagcttgca acgtcttcct ttattattgc ggagtgggga tttttggatc atgatgcttt
    55021 ttgcagcctt gttcgcttcg taagttctca caatggtgct tttgaaacat ttgaatattc
    55081 atgcggctac ggcggtaatg atcaaaatta tctattagaa aatccatttg cttctgtaat
    55141 gatcacacct tatatgatgg cgaggatcgt agatatttct ttgtttttgg aaaattatcc
    55201 atttaaaaag agacaagctg catttgccct acaaatagaa gaagatcatt atgcgaaatg
    55261 gaatgaagga atcgtggaag taacaatcga aaatggaaaa aatcatctct caaaagtaga
    55321 acaaacaaaa ctcccaatcg ttcgaggaag tatccaacat atcacgcagc tattattagg
    55381 gtatcgtaaa gtggaagagt tggtattcca agaaagaata caggtgacaa aagaatatga
    55441 agaaacgtta agctcaatct tgccacagca acagccaatt cttaatgact atttttgata
    55501 aaaaacgggt gatgacaata tttttgtcac cacccttttg tttttcattt ggcatttgaa
    55561 ggaaaatgtt aaagtaaatc ctcttttttc gtaaatttga attttttgtt ttcttttgtt
    55621 ttagggtttt cttttttgtg gtcttggatt gcttctttcg taatcttttc ccgatttttt
    55681 ttagatgaat ctaagcgttc tgcgtatact ttttcttttg gcttatcatt cattggaaag
    55741 gacctcccta cattatttca ttctacctct agtttatcat ctgttaagga ctagtggaaa
    55801 cgttttgcct aacttataag ctgatttttt tagcagataa gcttgcaagt aaaaaacaaa
    55861 caagctacaa ttgatttatt gaaattgttc ctgtagctca gtaggataga gcaatcgcct
    55921 cctaagcgat aggtcgctgg ttcaattcca gtcaggaacg tataaataac ccctgtatcc
    55981 tttgtggtac aggggtttgt tttgtatttg tgccaaaaat gtgccaaact agttatcatt
    56041 tttatataaa ctatcgaaca cagtattgat tttttcttta tcctgatctt caagctctcg
    56101 aacaatatga agataagtag acattgtagt ttctaaactg ctatgtccta aacgtttcga
    56161 tacgctaagt atatttactc cttgataaag taaaatagat gcatgtgtat gccttagtcc
    56221 atgcaaagta aattgctttt caatccctaa ttcttttaat tttttgcgca aatatttgct
    56281 gacggcgttt gatgaaacta atccattttt taagttgaaa aaaacaaaat tatgagggtt
    56341 tttaacttca aaattctcga ataattcttt ttgattgatt ttaaactttt ttaagagatc
    56401 aatcgtatgt ttatcaattg aaattttccg atttgaagtc tcgttttttg tttttcccca
    56461 ttcatttaat ttataattcc atgttttatt aatagtgatg atttgatctt cgaaatcgat
    56521 atcttcccat gttaatccta gaagttcagc aaatcgcatt ccagtagcac cagcaactaa
    56581 cacaagcata ggagaagagt actgtgcaga aaggttttct tctacgagtt tcattaaaga
    56641 tttaaattga tcataatcta aatatttatc ttcttttggc ttcaatgaat cttttccttt
    56701 aattactgct tttctagttg gatcaaacgg aattaatcct tcttctacgg catctttcaa
    56761 cgatgctcta atatggttat taaacttaat aacggtggat tttacatggt ctttcgcata
    56821 cttatttaaa aagcgttgat atccaactct atctaaatca gaaatcaata ccgctggcat
    56881 atatttcttt atgttcatta acgtatcttc gtattttcta taagtgatag gagatactgt
    56941 tccttcttta taaagttgca tccaatcctc aaagtaatct gataataata gatttttgcg
    57001 atccccttta aggcctttgt tcaagttata ttctaattcg ttggcggcat cttttgcttc
    57061 gccttttgtc ttaaatcctg attttcttat cttcgtgtat tttccgtcat cttttttgta
    57121 tgaaatttcg tattgccaac tatttccacg tttgactaat cttgccataa ttgaatcagc
    57181 tctctttctc tgatacaata ggaactataa agaagcctac tgtataggtt tgttttttca
    57241 tagaacacgc ttgctttgga cggtgggcgt gtttttatat caattagtta tgaagagcaa
    57301 ttgaaactgt ctctgttcca aagtaacctg tttgtgcttg caatacatta ttttgtgcat
    57361 ttgcttgggc ttcagagata tcaaaaacta ttttaccagt ttgttgcata tcaggattta
    57421 agctttccat aaagaaagag ttagtgatat taccattttc atcttgattt gccgacatag
    57481 atgcagccga atcagcttcg aaagtttttc catctgcttt taatttgaag aatgagctat
    57541 caacagtcac agccttatca cctgcatttt ttacagataa gtcaactact aagaaagtgt
    57601 cttttgcgtt agtaggaagt acagatgggc caacttgttt tactacttca acggagttta
    57661 ctttgtattc cattttccct acagcaacgt catcaccgat tttataagtc ttttcttctt
    57721 ttgctgtagt ttcttttgta gtttctttat tagtacttgt tgatgttgca gtagctgaat
    57781 ctttgttttc tccgccactt agagcaccac caataccaaa aaacaaaagt aatattaata
    57841 cccaaaacca cacttttttg taaaaaggtt tactaacttt atacattttc ccatcttgac
    57901 ccataacttt ttttgccatt taaatattcc tcatttcttg ttataatata tttgtgatct
    57961 cagaaatgag gtatgagtcc gtgttgcagc acgggctttt tttactgtgc ataagagtat
    58021 tttttcttga aataagactg gcaaacatta aaacattctg ttcttaactt attattgata
    58081 gaatagaact ccatgaaatt ttctaatttg aactgagatt catcagtcag ttcgttctca
    58141 ataaagatat ttagtaaaat cataattgcg attctatcag cttcagtttc gaattttgaa
    58201 tgaaaagttg tagagttatc gtacagtact gaatattcaa aatgtgaagc aatgaaatga
    58261 ccgagctcgt gggctaaatg aaaagcttca gaactgtctt cgtgtagttt ttcattcaga
    58321 aatactattc ttggttttgg ataataaaaa cctggttctt ccatttccat atagattaac
    58381 tttaaattat actcactcag catttctttc aacttcaaat acatacaacc catcactcca
    58441 actattcatt ttcctctaaa gctttagcaa ttgcaatcgc tttacgcatt gtctccttag
    58501 atatttcttt tccatcaaaa gaaaaaacag tatcgtcttc tgataaatcc acatgtttag
    58561 gggtttctct ttcttctcta cctagaaggt agtctacaga gactccaaag taatcagcta
    58621 accgagctaa ctcaatagaa ttaggagttt gtcttttcca acttcctaaa tatccattcg
    58681 aatacccgaa attcatttcg agctgtctaa tggataatcc tttttctttt gctaactcct
    58741 ttattatttc gtaagtattc attgataaat caacctttct gaatgcttac aaaaaaagtt
    58801 tagataaata atgtaaaaat agttgactta tatacattat taatctatac tatgttttgt
    58861 aaacaagttt aacaactaaa aagacaacaa aaaatactat tgattaataa atgccaaccg
    58921 ccaagaaagc tttttaaatc aaagtttaga tgtcttattt aactatgcat ttagtataga
    58981 ttattaatct aataaagtca acgcagtttt ttaaaaagtt gttaaatttg tttacgaata
    59041 taaaagaaag gagagaagaa tatggaaaaa acagtctcgg caaaaatcga agatttgaaa
    59101 ttagacatac tgaaacaagc aaaagtggcg atggaacacg cggtagataa agaagactct
    59161 gccatggttg cagccatagc agagatttta gctcacgttt agtcatcgtt tttacggtct
    59221 tctggaagct gaccatagat aacagcataa tgaatatcta aataagcttg agcaatttct
    59281 tttggcgaaa ttgattcgcc tttagtagat acttgtgatt cgtgatttag ccatgcaaca
    59341 actaaatccg cagcgatttc aaacggcgtt acactttgtg tcagttgcca taaagaattt
    59401 cacaatatgt atggtcgtgg taataatacc aaagagcaat ttgaggaatt tatggaaatt
    59461 aaaaaataca aaaaatcatt tattaaagga ggctaaacaa tgaacaagga aatgagccaa
    59521 acaatcaagg tacaaaaaat gatagatgat ctaacacatg gaattgatag ccaagccgat
    59581 aaaatcatca aggaattgca aggacaaaaa gttaaggatg caaaaatgct tctcaagact
    59641 atcaactttg aaatgaatcc aacaaaaaga aagctcgccg atgtgttgga agaaaagttg
    59701 gcttccgcta tcaacgagca agaattacta tttgaaaccg atacttttaa cagctgatgt
    59761 tttatagatg acagtttcat ccgaatctat atcatcgccg agagaaaaga atgttgcttt
    59821 tgacaaaaag ccgataagac ctacaagcgg tcttgatgtt gcaagagtag ataccccaat
    59881 atcaccttgc aaggtattca cgtaaatttg agaagaatag aacattccat ctttttcttc
    59941 gatatttgac gcatcatcgt atccaacgac caaagtatcg gcaaatattt tgattttttc
    60001 tccatcaagc atagtaatta caaattctgg tttcataaat tttcacctcc ttaacaatta
    60061 tttcagcctg tcacactgat aaggaaatta taccaaagaa aggaatgaga aatatgaata
    60121 caccacaaat ttttaatttc gagcaaaacg aagttcgaac tattttagta aatgatgaac
    60181 catattttgt aggaaaagat gtagcagacg ttctaggata ttcgaatccg caaaaagcta
    60241 ttcgagatca tgtggacttg gaggataaga cgcagaacga ttcgttcacc gtcaatggaa
    60301 cagcagttgt tttgattaac gagtcaggcc tttacagttt aatcttaaaa tcaaaacttc
    60361 cctctgccaa aaaatttaaa cgttgggtaa cgagtgaagt ccttccaaca attagaaaaa
    60421 caggtagcta ttcaaacgta cctcaaagtt ttgcacaagc attgcgttta gcagcggatt
    60481 tagaagaaaa gaaccaatta ctcgaacaac aaattgccga gtacgaacca aagattagct
    60541 acttagatac gattctttca tcgacagata cggtagctac ttctcaaatt gcagctgatt
    60601 acggaatgtc ggcaattgct ctaaacaaat tgctaaacga gttaggtgtt cagcataaag
    60661 ttagcggaca atggatactt taccgaaaac atatgaacca aggatacaca aaatcgcaca
    60721 caagtgagat accgaaagcc gatggcggca ctaaagttgt aatgaatacc aaatggacac
    60781 agaaagggcg agtgtttatt tacaacttat taatcgcaga gggctattac cctcaaatgg
    60841 atttagagga aattggttag aaaggagttt tagtatgact gacattgcag aaatcactca
    60901 acgagataga gaaaaaatca aagaatatgt cgaaagttca aagttcttaa cttacaccat
    60961 gcttgctgaa agatttggaa ttagcaaaag ctacttatct ttaattttaa acggtaaaaa
    61021 gacttctgca gaagcaaaca gaattataga ttcgattatc actatgtacg aattgtaaag
    61081 ggaggaacag caaatgcaat atctagaagc gaaaatccca attccagaag gctatgtaat
    61141 tatctcccaa gtggattatg aggagttgaa aaaagctgat gatactggta gatggatgac
    61201 gttgccagaa gtactagaac ggattaacag aaaatatgat tggtttactt ctagagtttt
    61261 aaagaaccca agatatagaa atattatcga tatcgaaaaa aacaaaaatg gatttgtcta
    61321 ttatccagtt gaaggaagag acacatatct atttttaaga agtaaaacac ttgaattttt
    61381 agaaacaaat ttttcggaaa tcttaaggag gtaagcggat gggaaaattt aatagagcat
    61441 tagtgttcag cgcaccccta atcatctacg ctttaggact ttggggaagc agacaagcat
    61501 taatcggcac gatcgtttac atggtttgga tttttatggg gcttgatgaa gctgagtaca
    61561 ga
//
LOCUS       DAFTHM010000005        60485 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFTHM010000005 DAFTHM010000000
VERSION     DAFTHM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.005"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(12..1535)
                     /locus_tag="L7C88_000352"
     CDS             complement(12..1535)
                     /locus_tag="L7C88_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBP9557212.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            1787..2968
                     /locus_tag="L7C88_000353"
     CDS             1787..2968
                     /locus_tag="L7C88_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBP9557213.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(3028..4656)
                     /gene="treC"
                     /locus_tag="L7C88_000354"
     CDS             complement(3028..4656)
                     /gene="treC"
                     /locus_tag="L7C88_000354"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBP9557214.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGENMSEGNGWNALFFNNHDQPRALNRFVVIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(5053..7764)
                     /locus_tag="L7C88_000355"
     CDS             complement(5053..7764)
                     /locus_tag="L7C88_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557215.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLPQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(7774..8475)
                     /locus_tag="L7C88_000356"
     CDS             complement(7774..8475)
                     /locus_tag="L7C88_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557216.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            8661..9260
                     /locus_tag="L7C88_000357"
     CDS             8661..9260
                     /locus_tag="L7C88_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBP9557217.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTIKKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            9341..10354
                     /locus_tag="L7C88_000358"
     CDS             9341..10354
                     /locus_tag="L7C88_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBP9557218.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            10462..11379
                     /gene="rbsK"
                     /locus_tag="L7C88_000359"
     CDS             10462..11379
                     /gene="rbsK"
                     /locus_tag="L7C88_000359"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBP9557219.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            11407..11802
                     /gene="rbsD"
                     /locus_tag="L7C88_000360"
     CDS             11407..11802
                     /gene="rbsD"
                     /locus_tag="L7C88_000360"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBP9557220.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            11802..13175
                     /locus_tag="L7C88_000361"
     CDS             11802..13175
                     /locus_tag="L7C88_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBP9557221.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            13532..15676
                     /locus_tag="L7C88_000362"
     CDS             13532..15676
                     /locus_tag="L7C88_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBP9557222.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(15728..16768)
                     /locus_tag="L7C88_000363"
     CDS             complement(15728..16768)
                     /locus_tag="L7C88_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBP9557223.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMGNGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(17045..18847)
                     /locus_tag="L7C88_000364"
     CDS             complement(17045..18847)
                     /locus_tag="L7C88_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557224.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIILGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(18861..19613)
                     /locus_tag="L7C88_000365"
     CDS             complement(18861..19613)
                     /locus_tag="L7C88_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557225.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(19622..19984)
                     /locus_tag="L7C88_000366"
     CDS             complement(19622..19984)
                     /locus_tag="L7C88_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBP9557226.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(20160..21032)
                     /locus_tag="L7C88_000367"
     CDS             complement(20160..21032)
                     /locus_tag="L7C88_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBP9557227.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21058..21570)
                     /locus_tag="L7C88_000368"
     CDS             complement(21058..21570)
                     /locus_tag="L7C88_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBP9557228.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQARGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            complement(21708..22499)
                     /locus_tag="L7C88_000369"
     CDS             complement(21708..22499)
                     /locus_tag="L7C88_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBP9557229.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(22554..23162)
                     /locus_tag="L7C88_000370"
     CDS             complement(22554..23162)
                     /locus_tag="L7C88_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBP9557230.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(23155..23472)
                     /locus_tag="L7C88_000371"
     CDS             complement(23155..23472)
                     /locus_tag="L7C88_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBP9557231.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(23628..24356)
                     /locus_tag="L7C88_000372"
     CDS             complement(23628..24356)
                     /locus_tag="L7C88_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBP9557232.1"
                     /translation="MPTGVLINVGSVLLGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            24515..25396
                     /locus_tag="L7C88_000373"
     CDS             24515..25396
                     /locus_tag="L7C88_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBP9557233.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARNFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(25633..26676)
                     /locus_tag="L7C88_000374"
     CDS             complement(25633..26676)
                     /locus_tag="L7C88_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBP9557234.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFLQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIG
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26679..27347)
                     /locus_tag="L7C88_000375"
     CDS             complement(26679..27347)
                     /locus_tag="L7C88_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9557235.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            27489..29825
                     /locus_tag="L7C88_000376"
     CDS             27489..29825
                     /locus_tag="L7C88_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9557236.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTDHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(29940..30251)
                     /locus_tag="L7C88_000377"
     CDS             complement(29940..30251)
                     /locus_tag="L7C88_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557237.1"
                     /translation="MKKMKESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            30432..31907
                     /locus_tag="L7C88_000378"
     CDS             30432..31907
                     /locus_tag="L7C88_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBP9557238.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGMSAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            31954..32538
                     /locus_tag="L7C88_000379"
     CDS             31954..32538
                     /locus_tag="L7C88_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBP9557239.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFGIVNEHSKRWQGD"
     gene            32540..32959
                     /locus_tag="L7C88_000380"
     CDS             32540..32959
                     /locus_tag="L7C88_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBP9557240.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKTL"
     gene            complement(33240..33524)
                     /locus_tag="L7C88_000381"
     CDS             complement(33240..33524)
                     /locus_tag="L7C88_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBP9557241.1"
                     /translation="MREIYSFESKIYASEVDKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNMPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(33876..34586)
                     /locus_tag="L7C88_000382"
     CDS             complement(33876..34586)
                     /locus_tag="L7C88_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBP9557242.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(34583..36055)
                     /locus_tag="L7C88_000383"
     CDS             complement(34583..36055)
                     /locus_tag="L7C88_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBP9557243.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            36193..36666
                     /locus_tag="L7C88_000384"
     CDS             36193..36666
                     /locus_tag="L7C88_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBP9557244.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(36819..37370)
                     /locus_tag="L7C88_000385"
     CDS             complement(36819..37370)
                     /locus_tag="L7C88_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBP9557245.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            37475..38005
                     /locus_tag="L7C88_000386"
     CDS             37475..38005
                     /locus_tag="L7C88_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBP9557246.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(38488..38931)
                     /locus_tag="L7C88_000387"
     CDS             complement(38488..38931)
                     /locus_tag="L7C88_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9557247.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(38947..40107)
                     /locus_tag="L7C88_000388"
     CDS             complement(38947..40107)
                     /locus_tag="L7C88_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBP9557248.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKKQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            40614..42314
                     /locus_tag="L7C88_000389"
     CDS             40614..42314
                     /locus_tag="L7C88_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557249.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQKKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(42416..43249)
                     /locus_tag="L7C88_000390"
     CDS             complement(42416..43249)
                     /locus_tag="L7C88_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBP9557250.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCQVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQSQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(43553..45718)
                     /locus_tag="L7C88_000391"
     CDS             complement(43553..45718)
                     /locus_tag="L7C88_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBP9557251.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            45978..48272
                     /locus_tag="L7C88_000392"
     CDS             45978..48272
                     /locus_tag="L7C88_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBP9557252.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGFPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            48265..48930
                     /gene="pgmB"
                     /locus_tag="L7C88_000393"
     CDS             48265..48930
                     /gene="pgmB"
                     /locus_tag="L7C88_000393"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBP9557253.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKCH
                     DHG"
     gene            48923..49930
                     /locus_tag="L7C88_000394"
     CDS             48923..49930
                     /locus_tag="L7C88_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBP9557254.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            49952..50971
                     /locus_tag="L7C88_000395"
     CDS             49952..50971
                     /locus_tag="L7C88_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9557255.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDPVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(51252..52619)
                     /gene="nhaC"
                     /locus_tag="L7C88_000396"
     CDS             complement(51252..52619)
                     /gene="nhaC"
                     /locus_tag="L7C88_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBP9557256.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFVFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(52729..54150)
                     /locus_tag="L7C88_000397"
     CDS             complement(52729..54150)
                     /locus_tag="L7C88_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9557257.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(54393..56270)
                     /gene="tdc"
                     /locus_tag="L7C88_000398"
     CDS             complement(54393..56270)
                     /gene="tdc"
                     /locus_tag="L7C88_000398"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBP9557258.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(56561..57817)
                     /locus_tag="L7C88_000399"
     CDS             complement(56561..57817)
                     /locus_tag="L7C88_000399"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBP9557259.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEVEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(57929..58134)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            58397..59698
                     /locus_tag="L7C88_000400"
     CDS             58397..59698
                     /locus_tag="L7C88_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBP9557260.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(59767..60366)
                     /locus_tag="L7C88_000401"
     CDS             complement(59767..60366)
                     /locus_tag="L7C88_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBP9557261.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT        18247 a        12373 c        10837 g        19028 t
ORIGIN      
        1 ttttttgcct atcagtgcaa aagcatttcc tgtgcaattt cacgtccatc cattgtatct
       61 ggataaaatg ttggccaatt ctccatttct ttcagcaata cttcttgact ttcatttcct
      121 gcatataaat gaaaatgttc ggagtcagcc ggtgcaatcg tgtgatcact gaattgaata
      181 tatctaaaag cgccactttc cttatcttct gcttcgaata gataccttac gccacggttt
      241 cctgcctcgt aggtcaagat ttctttccct acataacgat aatttgaacg tttcgttgtt
      301 ccatccttaa acgtaaatgc catctctttc tcactgatct tgattgaagc aatatctgtt
      361 tgatagccct tcgtataata ttctttatat tcttgtgctg tcttatcctg attcaatttt
      421 tctttatatt caaaaacagg atcaaaagtc ccatcttcta catacgtatc tactgtttgc
      481 caagttcctg cccaatctga aagagagcga tcttgtacat cctcgtcttc aaaataaccg
      541 ttgtagacgc tcttttcttt tttgggggtc aaagtatctt ctagcgggtt ttctgtctct
      601 gtcgtttttt tcaacgcttc gaggtttgct tccatgatag aaagatagtt ttctccattt
      661 tctatttgtt cattcgtcaa tccttccaaa ggattcaata cttctaaaga tacacctgct
      721 tcgtttgcta acgttctggc aatactatct ttggcgtttt cttcaaaata aatatagttg
      781 attccatgtt ctttaacaaa gtgtttcagt tcagcaattc tcgccgcaga cggttcttca
      841 ctagaagaaa gaccagcaat cgatacttga ttcaatccat attctaacgc tagatagttg
      901 aatgcagcat gttgcgtgac aaaagatctt tgttttgctt gcttaaaggt ttcttgataa
      961 agctgatgga gtgcttgaag tttctcggta taggctgctg cattttttgt ccatacttcc
     1021 tgtttttctg ggtaagcttc aatcagctga tcacgtatgt ttgctacctg cttgattgct
     1081 aaacttggag ctagccatac atgtgggtct agctcatgtg tatggccttc ttccccgtgt
     1141 tcatggtcat gatcatgtcc ttcttcactt cccggaagta aaagcatacc ttctgtcgct
     1201 tttatcgtat ggacattgcc ttcttgtaat gttttttgga ttgcggggac ccatgtttcc
     1261 atgttttcat cattataaac aaagatatct gtatcttgga tctttgccat gtctttagca
     1321 gaaggttcat aatcgtggga atcagtccct gctggaatca ataactctac ttctccttca
     1381 tccccgacga ttgcttttgt aaaatcatac atgggataaa aggtcgtcat cacgctcaat
     1441 ttttctttac tgtcctcggc tttcccactt gccccgcaag cagttaacat acctgctaaa
     1501 accagcatgg ccaatatacc tatcaatcgt ttcatttatg acactcctct tctcatcttc
     1561 tttcatttga atgttccgat tcgcttttcg caaaccgtaa tagttacgtt ttagcaacag
     1621 gatttaattt atcatatggt taaaagaact gtcaagcgtt ttcttatttt aattgatgag
     1681 aaagtttata tgaatgattg acgatatttt tgcaatcaac ctctatcatt ttccttttat
     1741 acccgctttt gtctataatg aagttataga taaaggagga aaaagagtga aaaaagaaac
     1801 agatacaacg aatcgtttga tccgcttttt aggaggaaaa acctcttact atgttttagg
     1861 aatagttatc ttacttgcgc tgatcattta ttttttccat cagatctcgt ttatattcaa
     1921 gcctgtcgga atcattatcg ctactatctt gcccccatta ttgtttgcac tgatcttgta
     1981 ttatcttttg gaaccagtca tcaaacgttt gagcaagcac ctttcgagga acttgtcagt
     2041 cattatcgtt tatgtgatta ttttattttt attggggctt ggaagcatat ggcttattcc
     2101 ttttcttgaa gaacaggcaa agacattgat cagtagtttg ccagatttgt ttcaagattt
     2161 tcaagagagt ctccgacaat ttttggagaa aacacctttt gccgattcat ttaatcaatt
     2221 ttttgcttct attgacgacg tgacgtctga tatagctgga tttattggaa attattggga
     2281 aagtggcgca caacggatca gcaacatttt ttcaactgtt acagctattt ttattacttt
     2341 atttactggt ccaattgtcg cttttttcct tttgagagat cctcaaaaat tttatcagtc
     2401 agttttagcg attgtcccac cagcatttcg tacagatttt aaaaatttga caaagattgc
     2461 taatcaacaa ttgggttcat ttctaaaggg gcaaatcatt gcttcattta tccttggagc
     2521 agtctactgg gtttgtttct tactgatcgg attagaattt gctagtgttt tagctatttc
     2581 tgctgggttg ttatgtatca ttccatatat tgggccgttt atcgccttct ttccaggttt
     2641 gatcattgca ttccaagact ctacttttat ggctgtcaaa tttgtcattg tctggtttgc
     2701 cgtacaactt ctccacggtg acttggtgat tcctcgagta atgggtgatc gtttacagat
     2761 ccatccgatt acgatcttaa tcgttttact tgtcatgggt gatctaatgg gaattgtggg
     2821 cgttattttt ggtattccta tctatacgtt agtcaaatta ctcgttactt ttattttccg
     2881 taaattcaaa caacgctaca ataaatttta tggcgataaa ggagagtatg aaaactcttc
     2941 attttctgaa gaagattatt ttaaataaaa cacaaaacgt cgatcttacg agaatagctc
     3001 gtaggaacga cgttttgtgt ttttgtttta atttttcagc aaagcaattg cctggtatgg
     3061 ttttagctcc agactttgat gaagaacagt atcggaataa ttatcgataa gaatattggc
     3121 ttctgtgaat ccttctggga tggcgatcct tgtatcttta tcatagaaat ttgttaatac
     3181 aagcagctgc tgtccttcaa attggcgaag aaagccataa acttccggat gatttgcttc
     3241 ataagcatga taatctcctt gtgcaacgat tggatatgtt tttctcagcc gaatcaattt
     3301 cttgtaatag gacaaaatag aatcttcaga agatagttct ttttctacat taatctcttc
     3361 tagcttgcct ccaactttta accaaggttt ccctgtagta aatcctgctt gttctgtgtc
     3421 tgaccattgc atgggtgttc gagagttatc gcgagatttt gctttgatcc gacgaaacgc
     3481 ttctttttct gtgaatcctt gttcaaggag taacttataa gcattcaaac tttctacgtc
     3541 aatatagtcg gaaatcgatg aatagtctgg gtcgatcatg ccgatttctt ctcccatata
     3601 aatatagggc gtcccacggt tcaaatggat catggttgct agcatctctg ctccttgttt
     3661 tcgatactga tcgataacta caaatcgatt gagcgcacgt ggctgatcat gattattaaa
     3721 aaatagagca ttccagccgt taccctcact catattttct ccccatgtat gaaatagtcg
     3781 ctttaattct gcaaaatcaa atggaggagt agaccattta ttcccatttt cataatcgac
     3841 tttcaaatga tggaaattaa agaccattga taattcttct ctactaggtt ctgtatacaa
     3901 gatacaattt tcgatcgtcg tagagctcat ttcaccgact gtgatgatag tggaatccgt
     3961 cccaaacgtt gcttggttca attcttttag atacgtatgg gtgattggtt tgtccgtata
     4021 ttcaggtttg ccatcatttt ctttattatt tttcaattgt tcgtctttac cgataacatt
     4081 gataacatcg aaacggaatc cttttacccc tttttccatc caaaaacgaa caactttgaa
     4141 tagttcctct cttactgctt ggttccgcca gttcaagtca gcttgtgtcc gatcatataa
     4201 gtgcaaataa tatttccccg tatctccaaa tggcgaccaa gcacttccac caaattttga
     4261 tacccaatcc gttggctctt ctcttaaaat gaagaagtcc tgataatgct ggtcccctgc
     4321 tagtgctttt ttgaaccatt catgttctgt cgaaacgtga ttcagcacca tatcgagcat
     4381 gatttctatc cggtatttct ttgcttcggc tattagctgt tcgaattcct ccatcgtacc
     4441 aaagatagga tcgatggctg tgtaatcaga gatatcataa ccgttgtctt tttgagggct
     4501 tggataaata gggtttagcc aaatcatgtc gatgcctaga tcattcagat acgggagttt
     4561 ttctttgatt ccttttaaat ctccaattcc atcaccatta ctgtctttgt aagatttggg
     4621 atagatttgg taaatgactt tgtctttaaa tgtcatggat atttacctcc attcaactga
     4681 tttattacct accacagctt atatatacaa gttatcattt attattataa ctgaacagaa
     4741 agcgtttgta aaatttatct ttatacattc taagaggtct gttgcccaat aaaaaacaag
     4801 agatcagaca tgtatttgtc tatcctcttg tttaaaatag caaaatattc ttgtttcttc
     4861 tataaatggt gttcaaaagc ttttatctac ggcaatcagt cttctcaaat gtaaaacatg
     4921 aggagctaat tttatttgag tattcttttt gctcgatgca ggacggcttt tttacaacct
     4981 ctgattcatg gtgttcaatt agcagctgac cctcgttatt agctcaaaac gctgatttca
     5041 caacctctgt ttttattcat tcgatttcaa cgcatcaatc atatcgatat gctttaattt
     5101 gaaatgggta acaatcatca caataaccgt aaatacgata gttaatcctg ctgataagac
     5161 ataagcccac catgtgatca ctaatggaaa gatgacattc tccatagacg cttgttgcaa
     5221 gatgaagtca gtcaatatat atcctacacc aaatcctccg atgattccta aaagagtaaa
     5281 gatgatattt tctcgaacaa tgtacatcgt gacttcttta tcaaaaaatc caaggacttt
     5341 tattgtagat aattcgcgta cacgctcgga aatattgata ttagttagat tatacaagac
     5401 gataaaagcc agcagtcctg ataatacgac aaagattaag acaaccgagt ctaagttcgc
     5461 cattgattct tcttgcgttt cgatttgttt ggacatgaaa gacgtatttg tcacagcgtc
     5521 tgtggcaagc agtttctcgg aaagcatttc ttcttctttt gttgtcatct tatctgtacg
     5581 cagcaaaaat gcattatcca tcatcgattg atcagtaact gaagcataat attcagggga
     5641 catataaata aagctaccta gatagttttt cacgatttct tttacttcga ctttccattc
     5701 tttttgatct tcatcataaa gcgaaatatg atctcctgta gataagtcaa atagttctgc
     5761 tactttttgc gtaatagcga ttcctgtttt aggcaaggag cgtgggttct cttcaagatc
     5821 agttaaatgg ataaaacgat ccaaatcagc tgttttactt ggtacgatca ctgtcagact
     5881 ttgcgaagca tgtccttttt ttctcaattc tacggtttga gtatgaatag ctaggatctc
     5941 atttactttt tcttgcttct gcagcatatc cgctgctttt tgacgactat cttccgtgga
     6001 tgaatccaat gtaacgattg cttgatagtc aatgatcggt ccaaattgtt tggctgaaac
     6061 agaacttaga gaatctttca atcccacgcc tgcaaccatc agcccggcac atccagcaat
     6121 tccgataatc gccataagca ttcttgactt atatcggaag agatttcggt aactgatttt
     6181 ttgattaaag ctaaggcgtg accacagcgg agtgatgtat tcaagaaaaa tgcgtttccc
     6241 tggcttcggt gctttcggtt gaagcaatgc agcaggccgt tctcttaaat ctttgaataa
     6301 aacgatcatt gcagcgccaa atgcggcaat gaagaatgcg gcagctgctt gtaaaatcgg
     6361 cggccagtca taaaaaataa gcgcactccc aatatcatac cgctcgttag acagctcaaa
     6421 aatgatcctt ggcaaaagat tcgttcctaa tatcgttcct aaaacaatac ctatccctga
     6481 ggctagactt gcatagattg catatttttt tgcgatttca actttcgtat aacctaacgc
     6541 ctttaatgtc ccgatttccc tgcggttttc ttctaccata cgtgtcattg tcgtaaaggt
     6601 gatcaatgcg gcaataaaga aaaagaaaac aggaaaaaca ttggcaatcg cagcgatacg
     6661 atcagacaga tcaccaaatt cttgaaaacc gacattttct gaacgttcat tgtataggta
     6721 tgatggttta gttaaatttt caattttttc tgcatttcga ttcaattctt cctctgcaga
     6781 ggccagttca cgttctttct caactaattg cctttcttgt tcagcaagtt gagcttcttg
     6841 ttgaggtaat gtttgaacag cgattgttcg ttgcgcttca ggaagctgct ggatagttgc
     6901 tgactgttgc gctaactgtt ttttagcatc ttctaaccgt gttcttgctt gcgttgtttg
     6961 tgctttgcca tccgctattt tttgctgtgc cggttctaat tcttcgttgg ccgatttttt
     7021 cagctcttct aagcgttctt cgggtcgatc ttgtaaatac ttttctgcct tttcttgatt
     7081 ttgctccatt ttatctttgt aagctttgct gtacgtattc aaattcttta cgtttgtaaa
     7141 atcaagatat aagacagaat aaatatctgt tttaaaaacg gattcaggta aatagacaaa
     7201 ataatcgacg ctaccatttc cgacgttcgc gtatcctctc tccaaattgt tgatgaacaa
     7261 tggagaacgg acaaagcccg tgatggtata ctctttttct ttcaattcat ctgaatcaat
     7321 ctgataaata tcaccgattt tatacccttc atcttccgct ttttcatcca atacaagctg
     7381 gtttggtttt tccgggagtt ttccatcagt taattgtagc ttgttctgct tgttattttt
     7441 gttataagaa aatatttgaa tcacttcgtt tttgccagta ttggaataat agatctgttt
     7501 tcctgtttct acttttgcat ctgggatctt ttctgcttga gcaatatctt tttgtgtcaa
     7561 gccaccagta gaaacgattt gcaaatcaga aagtcctgct gtaccaacat agtgatccat
     7621 cgttttttgc atgacaggtc cagcagtttt gacacctaca aataaaagtg ttcctagcat
     7681 gacaataagg atgattgcaa tgaatcgtcc tttagattgc cgaatttcgc gaaaacctgc
     7741 tttaagatat gttcttgttt tcataaaatc cccctaccat acaatctcat caatggatga
     7801 aggatgatca tttaattcaa cagaccttac tttagcatca ttaatgtgaa tgactctatc
     7861 agcgatgggc gctaaagcag aattatgtgt aatgatcaaa acggtattgc cgtgttgtct
     7921 gctagcgttt tgcaataatt tcaatacttg cttgcccgtt tcaaaatcca gcgcgcctgt
     7981 cggttcatca cataaaagaa gtttgggatt tttagctagt gcacgagcaa ttgaaaccct
     8041 ctgctgttcg cctcctgata attgggacgg aaagttattc aatcgatgag ctaggcccac
     8101 ttgcctcaat acctctacag gatcaagcgc atcaggagaa acttccgttg ccaattccac
     8161 attttctttt gctgttagat taggaacgag attgtagaat tggaaaacga accctacatc
     8221 tgttcgtcgg taagcagtaa gctgtttatc tgaaaattgc gcaatatctg tgtcatcaat
     8281 aatgatctga ccttcatcag gtgtatccat cccacctaaa atattaagaa tcgttgactt
     8341 tcctgctcca cttggaccaa gtataatcac taattcgcct ttttcaattg aaaaagaaat
     8401 atcgtcattt gctgtaatgg tcgtttctcc cattttgtat cgtttgtatt cattttttac
     8461 ttcgacatac ttcactctga ttcctccatt ttcacgatat ttctcgctat atctatgcat
     8521 cgaatgcgtt ttctcacact tatttatttt accactgaat ttctctagac taaagaaagg
     8581 aatcctttaa tttagttgac aaataaacga tttatgattt acttacataa aaaacattgt
     8641 tatttgaaag aaggaacatc atgaatgatt taaaggaaaa tatgattttt gatttatcaa
     8701 aaactgcttt tgtcgcgatc gacatgcaaa aagagatcgt aaataacggt acactctctc
     8761 cacacactgc agcatctatt ctgacaaaca atgatttgtt agtaagaaca ttgaaacgta
     8821 ccgctgcctt gaaagtttta gtgaacgtag acatctccac tttcccttat ttgagtcaac
     8881 aaactgatat gggtggaatg actgcttctg tacctccaga attcactgat ttacttttga
     8941 aggattcttt gaaagataca gataatatgt tgactatcaa aaaatacaat ccaagtgctt
     9001 tttttggtac ttctcttgat cttcaacttc gccggcgtgg aatcgaaact atcattttaa
     9061 gcggtgtagc gacaacaaac ggtgtatatg ctactgcatt agatgccttt caacacgggt
     9121 accatatcgt gcttgctgaa gatgcttgca gtgatcgtga caaagaatcc catcaattgt
     9181 tcataaaaaa gatatttccg aaaactgcac gagtacgctc aacgaaacaa ataatcgaag
     9241 ctatccaaca aagcaaataa gtactggcac acgtgatttt catttacttc tttttgattt
     9301 catgggaaaa taaccacagg atttagatag gagtatgaac atggtgaaaa aaaagatcac
     9361 aatcaaagaa gtcgctaaac tttccggcgt ttcaatcaca actgtctcct tgatattaaa
     9421 tggaaatacg gagaaattca gtccgaaaac tgttcagaaa gttttagctg ccaaagaaga
     9481 attaggctat cagcctgact attttgctag acaaatgatt accaaggaaa cgaaaacaat
     9541 tggtgtactc gttcctgata tcacgaatcc attcttcagt acactgatgc gaggaattga
     9601 ggatatcttg tataagcaga atttcgtcac gatattatgt aatgctgatt ctgatcatca
     9661 aaaagaaatc gaatatctag ccgagctcac acgtcgaggt gtggatggat tcattatcgc
     9721 gacttctgct gtctctacag atgcaatcaa cgaaaatttg aaaaaacaag gccggccctt
     9781 cattgttttg gatcagaaaa aatctgaagg atttagtgat gccgtacgaa cagacgattt
     9841 tcgcggtggt tacctagcgg gcatgcactt gcttagtcta ggacatcaaa cgatcgccct
     9901 tgtctatcct gaaaatccac cggaaaatgt ccacgctcgg attgaggggt ttaaatctgc
     9961 tcttgatgtt taccaaatcc ctcacgacca actgatcctc ttacctacac agttctcaaa
    10021 acaaggtggc taccagatca cagcagaact tcttgattct gctgcaactg gtgtgtttgc
    10081 tttaaatgat gaattagctt ttggattata tcgcggatta gaggaagctg gaaaaagcat
    10141 ccctgaagac tacagcatta ttggctatga taatatagat atgtgcgagt atatcaagcc
    10201 gaaactgaca acgatcgcac aaccaatctt cgaattggga caaacatctg ccaagttatt
    10261 gttagatcgg atccaattcc cagaaaaaga atgggaagaa aaaagattac ctgtacgatt
    10321 agaaaaaaga ttttcaactg cacccttgaa atagctttca aggtgtgcta tatttttatc
    10381 gaactattaa aacgttttac taaaacgttt taaaaaataa ttttcccatc aaaataaatg
    10441 agatagttgg aggtttgtaa aatgaacacg gttacagtaa ttggaagtat taatatggac
    10501 actacccttc gtttaaccaa catgcccaag ccaggcgaaa cgatgcatgc gcatgagatt
    10561 tttcacgctg gcggaggtaa aggtgccaac caagcagtgg cagccaaacg ttcaggcgca
    10621 cggacatctt ttattggagg cgttggggct gacagcgaag gacaacagtt attagatcta
    10681 ctgacaaaag aaaacatcga tacatctggg atagctgaaa tccaaggcgc cacaaccgga
    10741 caagcaatga ttatggtaga cgcagcagga gaaaatagta tcttgatcca tgcaggggca
    10801 aataatgctt tccatgaaca agaagtccta aaaaacaagc aactgattac aaacagtgac
    10861 tttattattg ctcagtttga aagtagctta gatgcgacga tcctagcttt ttctattgca
    10921 aaagacgcag gaaaaacaac gatcctgaat cctgcaccag ctcgtgaaac gattcctact
    10981 gaactacttg aaaagacaga tatcattata ccaaatgaaa cagaaacaga aatcattaca
    11041 ggaatcagag tgacagatca taacagtttg gtcgcagcag ccgaaaaact ccatgaatta
    11101 ggtattggaa cagtaatcat tacactaggc agtgccggcg ctttctatca tacagaaaaa
    11161 gaacacggta tcgtccctgc ttttaaagtg gatgccgttg acacaacagc cgcaggtgat
    11221 acatttattg gcgcattaag cagcacactt cagccagacc ttagtaactt gaaagaagcg
    11281 atcctttatg gaaatctagc ctcttctgtt gctgtgcagt cttatggtgc gcaaccttct
    11341 atcccttacc gcgaagcttt agaacaatca gcagtctaaa attaacaatg agaggaagaa
    11401 acaaacatga aaaaaggaaa agtaatcaat tcagatattt cacgagtaat cgcacaaatg
    11461 gggcactttg ataaattaag tatcggggat gcaggcatgc ctgtcccctt tggtactgaa
    11521 aaaatagatt tggctgtctc aaacggtctt ccaagttttt tatctgtttt agaaaacgtt
    11581 ttagaagaac ttgaggtaca atcgattgaa ttggcggaag aaataaagac aatgaacccg
    11641 gaaatattgg aaaaaatcaa attattgtta ccagatacac cgattagctt tatcccacat
    11701 gaagaaatga aaaaagagtt gaataactgt catgcattta ttcgtacagg cgaaatgaca
    11761 ccttacgcca atattatatt agtgagtgga gtggtcttct aatggaaacg acaatgaatc
    11821 ctgaacagat ggtactgtcc gagcagattc atatgctgat tgaacagttg ggaggaaaag
    11881 acaatattga ttctgtcctt ccatgtgcga ctcggcttcg tatcaaattg aaaaaacagc
    11941 cagtagccaa tgcagaaaaa ttaaaacagc aaatcccttc cattaagtat ttcattttac
    12001 tcgatagata tgcagaaata atcatggatc agggattggc tcctgcttac aaggaattga
    12061 cgcgtcaaat cgatcattca gctccgaaag aaaagctaaa tccgatcgaa aaactatttg
    12121 gtttgatatc ggaaatcttt acgccgatca ttccgctgtt tgccggttct ggtatattaa
    12181 aaggtctggt tgttttagcg actacgattg gctggcttag tgaaacaagc ggaacttatc
    12241 atattttgtc tgctgcgtcg aatgccgtct tttattttct gccaatcttt cttgcttttt
    12301 ctgctgccaa aacgtttaaa gtgaatggat atattgcggc tgtcattgct gcagcactga
    12361 ttgaaccgaa tctgacctct ttactttcag acagtggcaa agcagctact gattttctgg
    12421 ggattcctgt agtactgatg cagtatacgt ctactgtcat gccggcgatt ttaggtattt
    12481 tcttttattc ttttgttgaa aaattcctca aaaaatatat tcgcgaaaat atgcaattag
    12541 tatttgtacc tttactttca ttagttatca cggttccttt gacgttaatg gtattcgggc
    12601 ctgcgggtgt ttaccttggc gaaggtttag ctgccgcaat tacttggatg atggatatta
    12661 acggaccgat cagtggcgca atcatcgctg gtggttggaa tattttggta atatttggta
    12721 tccaatgggc tgtaaaccct gtcatgatca gtaatatctc tgcttatggg ttcgaccgaa
    12781 tcgttccgtt gacaggagca gccaattttg gaatggctgg tgcagcttta ggtgtatttc
    12841 tgcgaagtaa acgttcaaaa acccgttcga tctccggttc tgcttttgct tcgattttac
    12901 ttgcgggagt gaccgaacca actgtttacg gaattgcgat cccattgaaa aaaccatttg
    12961 ttgctgcttg cattggtgca gctgctggtg gagctgtaat gggatttgcc caagtgaaag
    13021 cgatcgcttt tgtatttggt agtctgacca cattgcctgc attcatttcc ggtacttttt
    13081 tctggtactt agcaggactg gctgttagtc tagtcgtagc aatgatcact actctcgtta
    13141 gcgggtttga tgaagaccta atgtcttatg aatagttaat gaaaaagact gaagtatgag
    13201 atgtttatca catatttcag tctttttctt tttaggatca ttatttttat aaatttttgt
    13261 gatactttcc aaactttggt ataatttaca tatgcataac catttttatc cccacttgtt
    13321 tatccccaaa caaaggtggt ctatgcaata aaatgaacgt caaagaaaaa cgaatgaatg
    13381 ctcgttgctt atttacaaat tgttttattt agaatacaca gacagattta tgaaaagaaa
    13441 aagcttttcg acacgattat ctgttccaaa aaatgtctaa tgaatgctga ataagacaga
    13501 aaatcaatga aaggaaaagg actagtttat tatgaaaaat aaaaaaacga tacgtttgct
    13561 agctgctact tggctgattg ctccgtctgt tttgtcgacc aataccgtat ttgccgtaga
    13621 taatcaaata gctgatcaaa cagtcacaac agatacgact acatccagct cagctactag
    13681 tgaaacaacg gattctttta cagaagaccc aactggaaca actaactcaa caacaggatc
    13741 gaccgagcca actgaaattg atccggctga tccatcagaa aatgaaaagc cagccgagac
    13801 atattccctt acaattgctc cttctttgat tggtaagatc caactgactg cttcgacagc
    13861 ggattcccct gaacagcaac ctttggatat tacggaaagt ggaacggtag aaggtttatt
    13921 agcggaaacg aaggtaactt acactattac gccagctgaa ggtgaacaaa ttgcttcagt
    13981 cgctgttaat ggtgccaaag aagtaaatta tgatgcaaag acctttacag taggtacgaa
    14041 caatttatct attactgcag aatttaaagc tggaccggat acttcaacag agaaaccaac
    14101 tgatcctagt gaagaagtcc ctagtacacc agatccggaa acgccaaaca aaccagatgt
    14161 gggtaataac aacaataata atggttcaaa taattcaaac aataataaca ataattcgaa
    14221 cagcgggaat tcttcgaatc aaacaaaccc atctggatcg aataacaatg gaaatactca
    14281 gagagaacca aaccatccaa acaatggttc atcgaatggc ggaacgaaca atgcttcatc
    14341 tcgtccaaat acagcaaatc aaagcggtat agagaatcca tcttctgctt cttctgattt
    14401 tgttgtaaaa tcaccaattg atgctgtatt gcctacaaat acaacgaatg tccaacaagc
    14461 aatcgttcga gaagcattca agcatcttgg aaaaccatat gtatggggag caaaaggtcc
    14521 aaatactttt gactgttctg gtttgactta ttacgtatat atgaaagcaa ccggtcatta
    14581 tatcggtggc tggacaggcg aacagcaata tgcaggtacg cagattccag taagtcaggc
    14641 ccaacctggc gatctcgtct tctggggacc ttcttccggt gttactcacc atgtaggtat
    14701 ctatattggg aacggacaat ttatccatgc gcctcaacca ggagataaag ttcgagtaac
    14761 ttctatttca gatttcacgc ctgattttgc tgtccgagta aacttagcag gtttacctgc
    14821 tgcttcaggt tcgctgacag gcggctcatc tattttagat ggattagatg gctcgttcca
    14881 tttcagtcaa aaccaaacaa ctgatcagtt cttgaaaaag attgcagatg atgcacagga
    14941 aatcgggcaa aaagaaggaa tctacgcatc agtcatgatg gctcaagcta tccttgaaag
    15001 tggatctgga aacagcttat tatcaagcga accaaatcat aacctttttg gtatcaaagg
    15061 atcatataaa ggaagcagcg tgaccttcaa tacacttgaa caagatagtt ccggacaaag
    15121 ctaccaaatc cgcgcacaat tccgtaaata tccttcttac aaggaaagtt tggaagacta
    15181 tgccgacttg atcaaaaatg gactgactgg caatcctgat ttctacaaac caacttggaa
    15241 gtcggaaaca aaagactaca aagaagcaac caaatatttg gaaggacgtt atgctacaga
    15301 tcgccaatat tcacaaaaat tgaacgcgat catcgaagcg tacgacctga caaaatatga
    15361 tgaaccgaaa aaagaagcag caacaactga agaagcaaac gctgaaatcc tcaatatgtc
    15421 taagcgattc gatgtgccaa tcaaatggac aacagatggc gtgccaatca caggattaga
    15481 attttcaacg ataaaacgcg tcaacaacgc ttcttccatc ttccgtgtcg cttcaatctg
    15541 ggatttgtgg aacaatttta cggcaagaca gataccagaa acaactactc gtacagttaa
    15601 agctgcaact gttcctgtac taaccttgtt aagtttagac aaatcattct ggcttgatct
    15661 gcctttaaag aaatagaata aattaaaaag gggatgtgac actgtcacac tcccttttta
    15721 atttattcta tttctttata tttattttgt attccgttac aaactcgcgt acttggttag
    15781 gttccagagt gacatctcca aaactttcaa gtcgctccgc tcctggcagt tcttgagtct
    15841 caaatgtgat accgccatga tttactaatt tattcccgcg catttccggt ccatcttctc
    15901 caaaatttgc tgtaaaaatc acgattcctg aagcatctgt ttttacttgg atcgatactt
    15961 tttcatctgg gcttgtcaat tccgcagcat ttagtaaacc agattgtttt ttcaacaaaa
    16021 atggatgatc gatgccgccc actatcattg attggcgaaa atcactggca aagacctcac
    16081 ctaatttttt aggacgttgg aagtcaaatg ctgtgccact tactgaaact acttctcctg
    16141 taggcgttgt atctttattg agcgtagcaa ataatcggct attcaaccaa agtatatgtt
    16201 cgtcgattga ctgtgctgga tcaccggtta aattgaaata gacatgattt gtaggattga
    16261 atactgtttt gcggtcactg atcccttgga ccgtcactcg ccatgtatca tcgttcgtca
    16321 gcgtataccg tacttctaca tctaaagttc caggaaatcc gtttcccata tctgggctag
    16381 tctgatagaa aatgaccgat gcttcgtttt caccattgat gactgtataa tgccactgct
    16441 tggcttcaaa gctaggtgca ccaccatgta aacaatgacc agtgtccggg tctgttttta
    16501 cttcgaacgt ttcatcatct aatttgaatg tgccattcgt aatccgtcca gccatacgtc
    16561 cgattgaagc accgatataa gggtcttttt ctagatattc ttttgcttca tcaaaaccta
    16621 agatcaactc tcgtttttca ttatcgatta ttgtttgaaa atgaacaacc cgtgccccaa
    16681 gatcactgac agacaaagat gtcccatttt gattcgtgat cgtaatcaag tgatagtttt
    16741 cgccaaaatt ttgttcattg atttccatgt tccttgcacc ctcttttctt tcatttgcac
    16801 tgattccagt atacatggaa accgttttct taacagctta ttccgtgagt aacgagaaaa
    16861 aatttactat attctaataa aagaccgtga aaaaaaggtt gtgacaaaaa tattgtcaca
    16921 acctcttttt ccgaacaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca
    16981 aacgaaaaat atgaggagct atttttgctt ggctgttctt attacttgat gcaggacagc
    17041 tttttcacaa tctctttttc aatacgattc cagtatataa ccatgtcgtc agtacatagt
    17101 agatgaaata caatacgaag aagatcgtaa acggaaccca aatatctttg tatggatttt
    17161 gcatgaatag accaaacatt tgtaatccga ataagacatg gactacacct aagattcctg
    17221 gtgctaagaa taacacgcct acttctctac ggatcgattg tttaagcaac ccgcgtcgtg
    17281 ttcctatctt ttcaagcatt tcataacgag caatgtcact cttgcttcct gacaagatct
    17341 tgaacatcaa acagctagca agcatggtca agaaagctaa acctaggaag aatcccataa
    17401 attcaaaacc agagaataga ccattataca cttcatacat ttcatatttc tggttgctgt
    17461 actctacttt ttgcaaagat ggattgttca ttttattttg agcaacaagt gtttcgattg
    17521 gtttcaggtt tgcttggaag tcttttacct gaactagctg taaagtggat tgtggcaagt
    17581 tcagttgatc aaattctgat tgactgacta ccttgatttc tttttcttgc tgttccggca
    17641 attcatagct tcgaagttcc tcttgtacag tcagttcatt cattttttta gcaggaactt
    17701 tttctttcgt gatcttcggc ggtgttccat cttcatgttt tatcatgatc aatggttgag
    17761 ccgcaaattc acttgcatta tagtaaatcg ttcccgcatc ttctttttga gtataagaag
    17821 cagaaagtgt tggtgaaagt tctttgattt tttgctgatc ttctgcccga ggattattca
    17881 tcactagatc atatccagaa ttgttttctg tcaagtctgc aatttcattt ttaaaaccta
    17941 atcctaccgt caaagcgccc agtgccaagg caaacagcat agcgaccatt gagagcattt
    18001 gtgtatattc acgaatacga aagtttaact gtgacaatgt gaaattgttc aattttttca
    18061 atgaaatctg ttctgatttc tttagtaatg ataaaaagaa aatgatcaca gaatggaaaa
    18121 tgaaataagt tcctaatatg atcgtaacta aggctacccc tataccaaag acttgatagg
    18181 tccccacgtg tttcatcata tagtaaccgc agcctagaaa agcaattccc agtactactt
    18241 caaggaaaaa caagaattta tgctgcttga ttcttgttgg tgtctgatcc gcacgaatca
    18301 atgctaaaat cggttttttg acaatcgaaa aagcattgac aacagcagct aataaaaaca
    18361 aaacagcaaa aaacaaaaca gtgatcaaca acccgtgaat actaaaaggt gtaaaatgcg
    18421 aaatattgag atctaactga tccactaata atcggtggac gatacttgtc aatcctacac
    18481 cgacagctga acccactaaa gtagctgcga tccctactaa gaatgtttca gaaaaaatca
    18541 tctgtgcgat ttttctgcct tttgctccca gcatcataaa cattgcatag tctttttgcc
    18601 gcatcgtcat caaaaaggaa tttgcatata aaatataaac gaatgtgatg atccctagta
    18661 aaacagaacc gaatcggaaa atgataactg tagccgcaac gatcgtatta cttttcaaaa
    18721 aagcttcgtt gcttgccatt gattcaaaca tgtaaaaaat agcagatgcc ataactaatc
    18781 ctgagaataa caccaagtag tctcttaaac ggctcttgat cccagtaagt gataatttcc
    18841 aaagcatagt caatctcccc ctactgttcc aagtttccaa gaatagatag tatttctcga
    18901 tagaaggaat cacggctttg atctccacgt ttcacttctt gatggatacc gccatccttg
    18961 atgaataaaa tacgttggca ataacttgca gaaaacggat catgcgtcac aagaagaatc
    19021 gatacatgat cttttgtatt caattcgtcc atcgtatcta aaagatcccg ggcacttttg
    19081 gaatccagcg cacctgtagg ctcatcccct aatagaatcg ttggttgtgt gatcaatgca
    19141 cgtgcggcgg cgacccgttg tttttgtcca ccggaaatct cagaaggata gctttccaaa
    19201 atatgagaga tggataaacg ttctgcaatt ttttggacac gttgcttgat ttcttttggt
    19261 ctgacgcctt gtaaagaaag aggaacagcg atattttctt gtgctgtcaa gctttctaat
    19321 aaattgaaat cttggaaaat aaagccaatc tcattcgcac gaaaatctgc tagttgattt
    19381 ccttttaatg tggtcacatc tttttgattg attcggatat gcccatctgt tggtttatct
    19441 aatgtggata aaatattcaa aagtgtcgac ttaccagaac cagaagcgcc catgatccca
    19501 ataaattcgc ctttttctac atcgaagctg atgccgctta atgcttgcgt ctttttctca
    19561 ttgttttttc cgtatacttt tgttacattc tgtacttcga ctattttgtt catttctttc
    19621 cctacccttt aattagtttt tccagtgctg ttttcggcac gtcttttttt tcgacttctt
    19681 catacgaagt gacaccttta tttttgttcc aggtgatttt taaatatgct cctttacgaa
    19741 gcggtcgagt caattgtccc ttgaagtcca gttctttttc cttaccctct ttcgtatagc
    19801 caggcaggat atatctatag ttgactgttt cttgtccaga gtctgatttt gaaactgttt
    19861 ttgtaccatc tgtcgtaatt tgtacatagt attcttctcc acccataact acgtaatctg
    19921 cgattttcac ccctgcaagt accacaacga tgaaaacaag tagaccgatc agaagttttt
    19981 tcactttttc cccttctctc ttactttata tactgattat agaaaaaagc gaacaattct
    20041 gccttcgaat caactatcat tcttctttca attttgtcat tttctttaaa acaactaaaa
    20101 aaagagttca agacaataat ccgtcctaaa ctccttcttc ctatcttaca aaaagtatgt
    20161 cacttacggt ctttcatgtc gcctgtattg ataacaggtt gcgttccttt gtctgtaatg
    20221 attgagacaa gtaaattatt gatcaattgg actttccgat catcggtgaa attgatttct
    20281 tgtccatctt cgatttgctc taaggccatt tgagtgattg tgacagctcc ttcaacaatg
    20341 gtttgtcgag cagacaaaat ggcttttgct tgttgacgtt ggagcatggc actagcgatt
    20401 tctgttgcat aggctaaatg gttcaagcgt gtttcgatta cttcgacacc tgctactgct
    20461 aaacgctctt gcagctcttt ttgcaactcg tcagacactg ccgtcgtgtt tcctcgaagc
    20521 gtcaaatcat tctcattgaa tgtatcatac gggtattggc tagcgatatg ccgaatggct
    20581 gtctcacttt ggatttctac aaaatcttga taatacgcta catcgaataa tgcctttgct
    20641 gtatcaacga ctttaaagac tactactgct gagatttcga tggggtttcc atccaaatca
    20701 ttgactttta aaacagaact attgaaattc cgaactttca acgaaacagt cattttttgt
    20761 gccaaaggta tcgtaaggaa aaagccattt tctcgaatcg tacctaaata ttgtccaaaa
    20821 aacaaaatta cttttgcttg attaggactg actacagttg ccgaacttaa caacaataac
    20881 gtgatcaacc aaagaaaaat acttaaaaaa agtgcccaaa ctttcgcttg ccacatacct
    20941 aaatagaaga aaaacaatcc aactaaagct aatacgacca atccgacaat ccctgcataa
    21001 ccattgatat aaaatgctct tttttctctc atgctacttc ctgcgctcct ttatccttca
    21061 ataaatatct aatgttactt ttttaatttt ttttcgaata cgcgccatta caccttctag
    21121 ttctaactct ttgtcttcag tgatgtacca accccttgcc tgtgtccctc cggctgcctg
    21181 cggtaaataa tccaattttg ttcgaaccca gtgcttttct tctgtaaaat agtcttctac
    21241 caagacctct agatccatcc ctgctgaaag aggcaaatct tcccgaacag atttaaagat
    21301 aaatcgttcc ttcttcccat catacttcaa tattcctgta tcgataatcg gtaaagaata
    21361 ataatccagc tctttcttca ccgtcaataa atgtttgaaa acttcatggt acacttgctc
    21421 taattggcga ccttctgaat tgttcgggta attaaccatc actttttctt tgtctggatc
    21481 atagaaggtt tggcttagtt gagtgatata agtatgtaat ctttccattt ctgtttttaa
    21541 cttttctctt tgaccttctt ctaccttcat atactctttc accctgtttt ctttttagat
    21601 attttctttc ttattttact atagttatgt gcgttaagcg atgaaaaaca gcaaagattg
    21661 gaaggatctt tgctgttttt tcttaaaata tccagttgag tacaggatca atctgtttca
    21721 ttgtcctctt gatccgtcgt aatattgatc gatgtgtctt tagcagtgat ctttagcttt
    21781 ttctgtcctt gttctaacaa agtatttgtt attggctggt agtctttttc aatataagat
    21841 tcaccagacg tttggatagt atagccactg ttttccatct catgcaaaga taaattgcca
    21901 ccgtttagga tgacttttcc ttctttgctg atcaaactgt cttctagatg gaagttgctg
    21961 ttttcacctg tgacgatcaa gttatccaca ttggcctcat ctaatcgaag tgagcctaat
    22021 tcatctttcg cagttattgt tcctcctgta aattcattga acgataccca gccatcatgt
    22081 gtcttagtat tcactttttt gattgatact tcgttgatat caattgcact attattccct
    22141 tcgattgtca attcagataa ttcatgatct gcagggacaa caatagtgat ttgtgcactt
    22201 gtgtcttcta aactaatgat tgcacctgtt gattttttga ctgcattcac agtcaacacg
    22261 ccatttttct cctttatttc tggcttttct gtcttatcat aagtcgtttt tatctcaaaa
    22321 tccaatccgc gtatgaccga aactgtttga ttttctgcat ggatgacgat tttgtttgca
    22381 tccttgattt tttttgtctc agtaaccata tcgatcaacc gaggaccatt atcccaagtc
    22441 agactctttt gagcgcctaa tgtataagtt gcacctgcta ggaggccacc agtaagcatc
    22501 agaccaatac cggtaatcaa aaaatgtttc aatctcaatt tatgtgtcct ccttcaaacg
    22561 cccgctgaat gcagatctct ttttgtaata aaacgtcgtc ccatccattt aacaaagttc
    22621 atcatgacat aaaaaagccc ttttgttcct ttcagcaaca gtggcgaaat aaatactgcg
    22681 cttcctgtgg cgaacagacc gacaccgata aagaataatc cactcagaat cgattgtcca
    22741 aacacactga ttcctgagat gatcatgaat aggccaacac ctaagatact gatacataaa
    22801 acatagatac taaaaatgag cgctagtaaa gcaaccaata gtcccccaat aaccaatata
    22861 aaccccagtg ctagtggaat gaggacagga gaagcaaata aaccgataat gattaaccaa
    22921 atcaggcgaa tttgtctttt tggatttttc actaactcgt tttctgcttg ttcttcttct
    22981 gaaaagtaac tgatttttaa ttttaaggca aactgctttg gtgtaccata ttcatcaatg
    23041 atctgatcta atgtttttcc agaatctaaa aaatattcct cataatactg gatcaaatca
    23101 aaacgatcgt cttcaggaat ttcttgaaga tgatccacaa cttcattcaa atattcattc
    23161 atttgtgctc tcctccaata accggtctaa agaatctcga aaaacaatcc attcatcaat
    23221 aatttcttct aaatgacgac ttcccattgg tgtcaacgag taatatcgac ggtttctgcc
    23281 ttcaaaaggt tcatcatagg tctcaagata tccttctttt ttcaatcttc tcaaaaccgg
    23341 atatagtgta gattcactga cagagagact ttcttgtacg atttttgtta aggcataccc
    23401 atacatatct tccttgctta atgctgctag cacagtacca tcaagaagaa cagttggaat
    23461 ctggatgtgc attacgtcac cttctattct caagtgtaat attttatttc aatctatatt
    23521 atacaacata taatatagtt tcaaaatcag tttgtcaaat acaaaaaaac tgactaaaag
    23581 atttgatcct ttttagtcag caaaaaatgg cttctctttg atttttatta taacagtggc
    23641 ataatccaat ttgtccacat ccagctcagt ggcatgataa cgatcattgc aggtatcatg
    23701 tcagctactg ggaacatttt cacgttgatc attctaaaac cggtagcgac catcaagaat
    23761 ccgccgcaag ctttaaaatc taagatcatg tctggtgtag tcaatggata aataaatttt
    23821 gccaataaga acaaaatata aaaaataatg aattggggaa ttgctatcac agaaacgaca
    23881 taccctaaat tacacgcaaa aatagctgct gtgaaaaaat caaggacaga tttagaaatc
    23941 aaaatcgtac tgtctcctgt catcccagaa tctaaacttc catagatccc cgtaccactt
    24001 gcacaaaata gaacaatgac cgtcactaat gtgctgataa attcatcgtg ggtcatacca
    24061 agcttttcac tagggaagat tttagaaata ggtacttgca tcagcgcagc ccccttattt
    24121 atcccattac ctaaatgaac aatcagacca atcgctgttc ctatcactaa agcaaaaata
    24181 acagccggca tatttttcat cggcgcaatg gaatagattc ccatccccat cgaacacaca
    24241 ccaaaaacca tcgtcagctg tgctttaaaa tgttcactta atttatttcc tactaatccg
    24301 ccaattagtc cgccaagcaa aacggaacct acattgatca aaactccagt tggcatcaaa
    24361 aaactcctct ctttttctac gaagcgaaaa aaatcagaaa aatttctgta attattgctt
    24421 tcgctgcaag aaagattgta acagacagag aagattacac caattcattt tttgtgttaa
    24481 agtattcttt attggaataa gtaggaggaa tatgatggat atccataaat tcgaagtttt
    24541 tcttgattta gccgaaacaa tgaatttcac caaaactgct gatcgacaat tcaccaccca
    24601 aggaaatatt tctaaacaga ttctttcgtt agaaacagaa ttagacgtca aattattcga
    24661 acgcgcccat agaaaaatcg aattgaccga agctggaagc ttattgctcc catatgtaaa
    24721 aaatgtcgta gaacaatacc atgctatgca agaagtgctt gaaacctata cgaaagacaa
    24781 caatctttca ttaaatatct taacgatacc gacaatgatc aattataaag gtttttccaa
    24841 aatcaccgag tttttgaaac gccatcctga atttacagtc cagttgaaag aagtggaaag
    24901 tgtcgaatta acttacaatg acgccaatga acatagtgac acgatccact ttgctagaaa
    24961 tttccaggcc ccaccaagtt cgattgagtg gttgcctact gaaacagacg attttgtagc
    25021 agttctacct aaaaatcatc ctttagctag taaaaagaaa ttggatctaa gcgaactgaa
    25081 aaaggagaac tttttgctcc ttggccccac tacgaacttg tatcaacctg tactagatct
    25141 gtgtcgcgaa gctggatttg aaccaaaaat ctcttataaa ggagcaagaa tcgacttgat
    25201 catcaatatg attgcaaatg acatggggat tgctattgtt atggaaaaaa cagtcaagaa
    25261 tctattaaaa gaaaatactg tgattctccc tatttctcca acaacagaga gttatcttgc
    25321 atttactcgt aaagtcggtg agcattcttt ggcttcagat acattttggg agtatttaaa
    25381 tcaagaagaa aactaagccc tacattttct gtccatctat ccacccaaaa aaagagagcg
    25441 acgcatgact ttcgctctct ttcttgcatc atgtccttgt ttcaatgaca cctctaacat
    25501 ttctcgtagt tcaataagaa agcagcgatt tttatgccaa aagaaccgta agaacatttc
    25561 cctaatcaca aaaaaacgac taaaaacccc taaaaacctt caatagaatt tttaggggtt
    25621 ttattctttt tcctattgtt tacttaaccg tatcattgct gtcgttccta ctccttcgat
    25681 actgctataa tcaatacgtc catcatgcag ttctagaatt tttttaacca gtgaaagtcc
    25741 tagcccattc ccagaaattt gacgacttgt atctccttga taaaattttt caaacattcg
    25801 atctctggtc tcttcattca ttcctacacc tgaatcggtc acttccagtc caatctctgt
    25861 ggctgtctca aatagtttga tatgaatctg tccattgatt tgattgtact ttatggcgtt
    25921 atccatgata ttcagccaca cttggtacaa aaactcttca ttgcctgtgt aatttactgc
    25981 agcaagttcg atatccaatt ctagctgttc tttctcccat ttaggctgca aaaaaacgat
    26041 tacttctctg atttgttcat ctaatcgata ctctttcttt tccagttgga tacgctggtt
    26101 ttccagtttg ttcaatttta agatgttctc tgttaattgt gaaagctgcg tgatactttc
    26161 gataatccga tataaaaata tttggcgttc ttcgtcagag agatttgggg cttgtaacaa
    26221 ttgaacatat ccttggattg ttgctagtgg tgttttgaat tcatgggata cactggacac
    26281 aaagtcattc ctcagtgtct cgatactatt gagttcttgg accataacgt tgaaatcttt
    26341 atacagttgc tgtacttctg ctactttctg ctgttcatcc attcgaatcg aaaaatctcc
    26401 cgttgctacc agactcatat ttgtccctag cgcactgatt ggatgcagga tacgccgccc
    26461 aacaaaaatc gatattcctg tacccacgac catactgaac cccgcaaaga cgaataacgg
    26521 gtataacgtt ggttttccag ccgattcagc aggcgagata gaatgtcgag acaataagaa
    26581 aataaaaccg agaaaacaca gcagtgtcac taagatcgaa atgaagacaa tactagcaaa
    26641 atagatccat aattgtgaaa atagcttttt tttcatcttt aaataaccgc cttatagcct
    26701 agtccccgta ctgtgatgat ttgaaaatct tccgtctttt caaaacgggt ccttaaacgt
    26761 ttgatatgta catcgatcgt tcgttcttct gtattcgtat ctaatcccca aatatcatcc
    26821 atcaactgtt ggcgagtgaa gatcttgttg ggataagaca gtaatttata cagaagcaga
    26881 aattcttttt gaggcagaat caacgaatgc tgatcttgta acactgtata agcatctagc
    26941 tctaattttg tttgtccgat tatcaagcta ctgctgtaat tgatctttga acgtcgaagc
    27001 aatgcttcca cacgtaggat catctcattg acatcgatgg gttttgtcat ataatcatct
    27061 gctcctaatt tgaacccgcg tttcttatcc tcaaaatcgg cctttgccgt aatcattaga
    27121 acaggtgtgt caaatctggt gctacgtaat gagtctagca agtcatagcc atccattttc
    27181 ggcatcatga tatctgtaat gattaattct atacgtgtcg cttctagttt tttcagcgca
    27241 tcctctccat tcaatgcggt gatgactgaa aagcccgctc gttccaacac agaacggtaa
    27301 agcaactgta attgcggatc atcttctact actaaaatac gattcattga tctccctctg
    27361 ttttttgaaa aatttctaga ttttttcttg tagttcatct tcagttaaca tttatttcgt
    27421 atactacgat cattgttctg atatacttat tagtataccg aatatttcaa tacgggagaa
    27481 gggtgattat gcttcaatta aaagatataa aaaaatatta taaagtcggc gaaaccacca
    27541 ccaaagcatt ggatggtgtg tctgtcgctt tcagacaaaa agaattcgta gcgattttag
    27601 gtcctagtgg ttctggtaaa acgactatgc tgaatgtgat tggtggacta gataattatg
    27661 attccggtga tatggtaatc aacggaaagt ctactaaaga ctttaaggac agtgactggg
    27721 atgcctaccg aaacaactct atcggtttca tttttcaaag ttacaacttg attggtcatc
    27781 taggcattat tgaaaacgtt gaacttggga tgacattaag tggtgtttct aaagacgaaa
    27841 aacgaaaacg ggcagaagat gcattgcacc gagtcggctt gacagatcat atgcataaaa
    27901 agccaaatca gttatctggt ggacaaatgc agcgagtggc catcgctcga gcactagcca
    27961 atgacccaga tatccttttg tgcgatgaac caaccggagc gttagataca gaaacaagta
    28021 tccagatcat ggaattgatc caagagttat cgaaagaaaa attagtgatc atggtcacac
    28081 ataatcctga actggcccat caatacgcag atcggatcat tgaattttct gatggtaaga
    28141 tcttaacaga ttcccatcct cacatcgaac gaccaaaaga tgatcaattt aacttacgca
    28201 gaacaaagat gagtttttgg acagcgttaa agctttcctt caacaatatc cgaacaaaaa
    28261 aaggacgtac tttcttgacc tcctttgctt ccagtattgg gatcatcgga atcgcgatcg
    28321 ttctgtccct ttcttctgga ttccaaaaac aaatcgataa cacgcaagct gaaacgatgg
    28381 cgaaatttcc gattactatt tctaaggtaa cgactaacca gactcgtgac gatgccggat
    28441 tgggtgcaag caaagcggat tatccagaca gcaaaacgat tactgcaaaa gtcagcgaag
    28501 aagataaagc acagcacacg aataagattg atcaaacata cgtcgattac gtaacagaca
    28561 tcgatcctaa cttaagtaat aatatcggat ttacccgtac tacaggaatc aatcttttac
    28621 gtgatgtaaa tggcaaagta cagcctgtca gcttctcgaa tcaaaatcct gatacggaat
    28681 ctctttcttt atctagtacg atgtcagcaa tgacaggtgt gggagtgtca agtttcccta
    28741 cacagcttga cactagcaaa gaaaactttt taaaagacaa ttattcttta cttgccggaa
    28801 gttatccagc ctcagcaaca gatgtcgtgc tgatcgtaga cggcaataat aatactaata
    28861 tcaacgcatt gaagaatctt ggatttgatg tgaaagaaga cgaaaaactt gattttgatg
    28921 atatcgttgg tacaacattc aaattagtaa acaacaatac ttactataca aaacttccaa
    28981 ctgggaattt tatccctaat acagattatg atgcgatgta tcagaatgct tctgatgaat
    29041 tgaagatctc ggggatccta cgcgtgaaat cttcttctac aatgaatctc ttatctccag
    29101 gaatcgctta tagcgatcaa ttaacgactc aaatcgtcaa cgaaaacaaa gaatcagaaa
    29161 tcgtcaaagc tcaaagagac agtggtgtaa atgtcttaac tactgaaaaa gttgacgaaa
    29221 atgccaaaca aacattgctt agttatttag gtggagacag cttgccttca agtatcatga
    29281 tttatccgaa caattttgaa gacaaagaaa agatcttgga ttatctagat gattacaata
    29341 aaggcaaatc agatgaagat aaaatcattt atactgattt agctggaacg atgactgaac
    29401 tgactggcgg attgatggat gctatcactt atgtccttat tgcttttgca gggatctctt
    29461 tagtaacaag tatgatcatg atcagtatca ttacttatac atctgtgatt gaacggacaa
    29521 aagaaatcgg tgtactaaaa gctttaggtg cacgtaaaaa agacatcact cgcgtatttg
    29581 acgcagaaac gtgtatttta ggtatttctt ctgggatatt aggtgtgttt attgcatggc
    29641 tagctacgtt ccctatcaat agcatcttat acaacatgac ggatctaaaa aatgttgctc
    29701 aactaaatcc tgtccatgcg attattctag tgatcgtctc tactatattg acgatgcttg
    29761 gcggtcatct tcctgcacga atggcagcga aaaaagacgc cgctatcgct ttgcgtgcag
    29821 aataaggttg tgacaaccac atttagattt gagtcataag agcgctgaaa tagtagaaaa
    29881 cagcaagaaa cgaggaagta atatgttcct tgtttcgcgc tgtttttttt aattattttt
    29941 tataattctg gtatactttt ctttcctttg taccacaact cttctggcgt atacctgtct
    30001 tttccattta tgaatactgt tccatctgct tcaatcgtta cttcagtccc aatccacata
    30061 ttacgagaaa gtgcgagaag attttttctt tttcctcttc ctttttttcc aaattgcaag
    30121 gcatcggtta tctcttctgt ccaatgagat ttcacgtatt ttacttctcc gttttcaaat
    30181 gtaactttca aaatattcgc tatattttcc acttttactg ctttaggaaa tgactccttc
    30241 atttttttca ctttccttcc tccaacacta agtatgcgct ttcttttagt gataagtata
    30301 tcatagttta ttctattatc aaaaaaacgc atccattcca ttgtagaata ctttaccgaa
    30361 caagttgaat tgttttcctc tttttcacct tttactatag ataggtaaag acaactaagg
    30421 aggaatctct catgacagat caaccgtatg atttaagaaa agtcatcgaa gaactaaaaa
    30481 cacttccagg tcaatatcac gaaacagata ttgaaatcga tcctgaagca gaattatctg
    30541 gtgtttaccg ttatatcggt gctggcggta cagtaaaacg tccgactcaa gaaggaccag
    30601 ctatgacttt caacaatatc aaaggtttcc ccggcacacg tgtgaacatc ggaacaatgg
    30661 ctagtcgtaa acgtgtaggt gaaattttgc accatgatta tcgaacactt ggtcgtttct
    30721 tgaaagacgc tgtagaaaat ccaatcaaac ctgtgaaagt agacaaagca gacgctccag
    30781 cacaagaagt cgttcatcta gctaccgatg cagacttcga tattcgcaac attttgcctg
    30841 cacctacaaa tactcctgaa gatgctggtc catacatcac aatgggtgta gtcttaggat
    30901 cagatccaga aaaaacaatg agcgatgtaa cgatccatcg tatggttcta gaagataaag
    30961 atacgatcgg tatgtacatc atgcctggcg gacgccacat tggtcacttc caaaaacaat
    31021 tcgaagcctt gaataaacca atgcctatca ctatcaatat tggtttagat ccagcaattg
    31081 ccattggcac gactttcgaa ccacctacca ctccacttgg ctacaatgaa ctatggtgtg
    31141 caggagcttt gcgtaacgaa cctattcaaa tcgttgatgg tatagcagtc gatgaagtgg
    31201 gtattgctcg tgctgaattc atcattgaag cagaaatcat gccaaatgaa acaatgcaag
    31261 aagatatcaa cacgaactca ggaaaagcaa tgccagaatt tcctggctat actggggatg
    31321 ctaatccagc tgtacaagta gtgaaagtca aagcagttac tcaccgaaaa gacaatccaa
    31381 tcatgcaaac aacgattggt cccagtgaag aacacgtatc tatggccggt attcctacag
    31441 aagcaagtat tcttgccttg gtcgataaag ctattccagg aaaagtagta aatgtctaca
    31501 atcctcctgc aggtggtggt aaattgatga ccatcatgca aatccgtaaa gaaaacgaag
    31561 cggatgaagg tattcagcgt caagcagcta ttcttgcttt atcagccttc aaagaattga
    31621 agacagtcat tttagtcgat gaagatgttg atattttcga catgaacgat gtagtttgga
    31681 ctttcaacac tcgtttccaa ggagataaag atatcatcgt gatcccagga atgaggaacc
    31741 atccattgga cccatcagaa ttaccagaat ataatcctgg ctctattcgt ttccgtggga
    31801 tgagtgcaaa aactatcttt gacggtacag ttcctttcga tatgaaagaa cattttgtac
    31861 gtgcaaaatt ccaagaagta gaagattggg aaaaatattt gaaataatga atgatctgca
    31921 actgttttga catcataaaa aggagtgcgg aaaatggaac aattggcaca acggaagaaa
    31981 aaaatcgtga ttggtgtaag tggcgcttca ggcaccattt atgccatcaa cctagtgaag
    32041 aaactaaaag aatatccgat gatagaaaca cacggaatca tcagtccatg ggcaaaacag
    32101 aacttaaagc tggaatccga cttatcacta actgaattcg aaagcctgtt tgattaccat
    32161 tattcaaaca aagatttagg tgctgctgtc gccagcggat catttttgac cgatggaatg
    32221 atcatcgtac cggcaagtat gaaaacagtc gcaggtatct ctgttggttt aggcgacaac
    32281 ctgattgcac gtgctgctga tgtaacaatg aaggagcaac gaaagttagt cattgttcct
    32341 cgtgaaacgc cattaaatgc cattcacttg gaaaacttga ctaaattagc acgactaggt
    32401 gtgcaaatca taccaccaat tcctgctttt tataatcagc ctcaaacgat ccaagatctt
    32461 gttaatcacc atacaatgaa acttttggat caatttggaa ttgtaaatga gcattcaaaa
    32521 cgttggcagg gtgattaata tggaaaaaga aacgatagtt gaagtaacca aactaggttt
    32581 cacgatccaa gctgctgtta aagtaatcgg taaagactta ttgatcactt taacaggcgg
    32641 agatacacca catatcggaa cagtcactac attttctcgt gatacagaga tgcaaactgt
    32701 acgtttccct agccacgatg gtcggttcca taaagacgat gtcttagccg aaaaaatagc
    32761 tgtgatcatc aaaactgccg ttccgggaag ttgtacgatc acttccggta tccatgttga
    32821 ccatatctcc aatgcacaaa tcaacgcctc ttttccgatg tcagaagagt taggttacaa
    32881 gattttagat tggttggaaa aaatagattt ccatatcaaa gaaccagttt attataaaga
    32941 tggtgaaaaa acattatgaa agaagaggtt gtgaaatcag cgttatgacc tgagtatgag
    33001 agaaaaaaat ggaaaaatag cttctcatat tttgccgttt ttgagctaat accgagggac
    33061 agctgattga acgccgttta tcaagaggtt gtgataaagc cgcttcgttt cgagtagtaa
    33121 gaaaaatttt gtaaacatgg gtttccacat ttttgcataa atttgactta ctaccgagaa
    33181 actggctttt gaacaccgtt tatcaagagg ttgtgacacg tcttttgtca caacctcttt
    33241 tatttttgct tcactgtaac tgctacaata tcaccgattt cttttccgat gtttttacga
    33301 atatcttttc gtagtccaag gatgtagcag actgaaccat ctggattttt cacgcccata
    33361 ttcacgatac tgccttcata cggcatattg tcaaaagttg cttggacttt aactcttcca
    33421 gcaccgaatt cttttcttat atcatacgga aaaataatat atgccccgcc cttgtcgact
    33481 tcggaagcat agatttttga ttcaaaagaa taaatttccc tcattttatt tctcctattt
    33541 tttacatcta gtatagcata gcaaaaaaaa gaaggaactg tgacaaaagt cttgtcgcag
    33601 ttcctttttt cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatagt
    33661 caacaaacat gagaagctgt tttttgaaat tgctccttgt gactcagagt taaacggcag
    33721 gctcacaacc tcttccttaa acggtgttca aaagcttgca tctacggcac taagcccaat
    33781 cagatgaaaa atatggagtg ctatttttat ctgattgttc ttactgcttg atgcagagca
    33841 gctttttcac aacctcctac atggtgttca aaatattatt cgccttttgc ttctttcact
    33901 aattttgcga atgcttgttg ttggaattca gcagctaagg ctttcgtacg ttgttcttgc
    33961 tctgctttgc tcatttttgg attttcagtc attgctttta ccataccgtc ttgaacataa
    34021 gcttttgctt cactttccat cgtactttgc tgtttcttca ctaattcagc taacttggct
    34081 gcttggtccg tacttaattc tacccatgtc tctgggattt tgaatgtatt cactcggctg
    34141 tcatattcgt gattgttatc agcaatattg aaccagaatt tatacatgtc gtttttgtat
    34201 tcccaataag tagttttcgt cactttttca gcatcgccgt ctgtcttttc tactttattt
    34261 gtttcgttat ccgtaccagt tgcttttggt ttttcttgtt tttcatttgt tcggtaaaga
    34321 tacacttttt cttttccatt ccctaaagct ttatacaaaa gcatatctgc tccttgggaa
    34381 tcagcactgg aaacaatttt ttctgttttt gtttccgtta ctttttccat tccaaagtga
    34441 ttggacaaat tagcgacgat caaacttagt gaagcgacga agattagtcc gaaaatcaaa
    34501 gataaaaagg tttgccatgt ttttttagcg aacacgttcg ttaaagcaaa agcaagcaag
    34561 ctgacaatca aaactccaat aatcatgcat tatcccccgc tttcattaga acaggttctt
    34621 ttttcttcaa taaaaaggca ataataaagc caagaatccc aaagatgatc gctacgataa
    34681 acgcggcatg gtaacctgac agtgtggcat tgattgcctg atctttataa gctaatggcg
    34741 tattatccaa tacagatttg cttgggatat ttgcttttgt cacattcgtc aacacactga
    34801 tcaaaatagc tgtaccaatc gagcttgcga tttgacggaa tgtattattt accgctgtcc
    34861 catgactgat caagttattt ggcaatgcat tcataccaga agtcgttacc ggcatcatga
    34921 ccatggagat cccaaacata cggatcgcat aaaggatcac gatatataaa actggagtcg
    34981 tttttgtcaa gaaagcaaat ggtgcagttg ccgctgtcaa aatgaacatc cctgtgatgg
    35041 ctaaacgttt cgcgccgtat ttatcgaaaa tcgcacccgt cacaggcatc atagccccca
    35101 tgatcaatgc acccggcaac aacatcaagc cagaatggaa tgctgattct ccacgaatat
    35161 tttgaatata caatggtacg accatttctg cccctaccat cgccatattt gttacaccag
    35221 ctaaaacagc tgcaatcgtg aatgtagatg atttgaatac acgaagttcc aagaatggat
    35281 gttccaaatg taattgacgc catgagaaca aggcgatgaa aatcacacca acaactaaga
    35341 aaccaattac tttcaagctt ccccagccgt catctcctac actagaaaat ccgtaaagta
    35401 aactaccgaa tccaatcgtt gataaaatag cggataaaat atcaatgcta ggatttgaca
    35461 atggaataac acttttcatt aggaagaatg ctaaaaccaa gacaagaaca acgattggca
    35521 gtaccatacc aaacaagtca cgccaatggt agttatcaat gatataacca gataatgtag
    35581 ggcctaaagc aggagcaagt ccaataacga tccctgacat ccccattgct gatcctcttt
    35641 tttctggcgg gaaaatagat agcatgatat tttgcaataa tggcatcgat actcccacgc
    35701 cgcaagcttg gatcaagcga ccgattagta atgtactaaa attaggtgct gtaaagcaag
    35761 taatcgttcc gatcaaaaag atcgtcatgg cagaaagata taaatttctt gaactgaatt
    35821 tattgatcag ccatgctgtt attgggatca tgatcccgtt gactagcaag aaaccagtcg
    35881 ttaaccattg cacatcagac gctgaaatat cgaaagcttt catcaatgta ggaaaagctg
    35941 tcgtcaataa ggtctgattc aaaacggtac aaaatgtacc aattaataag acaacaacta
    36001 aaagtgtccg attatatggt tttccgtaaa tatctacggg ttggttgtta ctcatatttc
    36061 tccttctttc tgaatttttt ctgaaactac tagaatactt tagtcctaaa ttcgctattt
    36121 gtcaacctac ttgacacata agttaatacg gatataatta agggaagcaa gaggacaaaa
    36181 ggagtgacaa aaatggttgg ggcttccctt aaacgtttgt tggaaaatga tcaattggtt
    36241 gttggcatca gtgaattaag tgatatcgta ggtgtgtctc cacgtcaatt aaggtattgg
    36301 gaacaaaagg gattcattcg ttcgatcgaa gctgatgcga attgtcctag aaaatatcgt
    36361 ttacctacag tcataaaagt agaactgatc aaaaaatatt tagatgacgg atttactttg
    36421 tcaaaagctg cagaaaaggc agaaatccgc caaaagaaaa tgcaccatgt ccgtaaagtt
    36481 ttttcaaaag caatcaaaga tatcgaattg atcgacgaac gctatacgat tttacaaatc
    36541 ggtaacttca aagaagagaa tgctaagatg tacatcattc atgacaacga gacagacgaa
    36601 ttaacttaca agctccttcc tgtcgatgaa aaagctgact acgaacagtt gttaaaagaa
    36661 ctctaaacgc cactaatctc ctaagtacca agctttttaa taagtagatg ctacataaat
    36721 acttgaaaaa aggcctgttt gaacataaga atatccgaac ggtgatctgc gtttctttca
    36781 tatagaaagg aattctccat cactgttcgg atattttttt atttttttcg gttactttct
    36841 tctaatacat ctgttagcca atttgcatat tctgtttccc gattgatcgc atgcgctaaa
    36901 atcaggtagt gtccgtaatt ttcatgtttt tctttttcag taggaaagat cgtttttttt
    36961 cgctctaata gatgaagtcg tttttcttca tgaaggtcac gctgctgctg aataatttct
    37021 actaatgccg gatcattcac gtctttgacg aaatacaatt tcagaacaaa ttcgtctcga
    37081 ttaaccggta gttcattggt tggtgtatga atccactctg ccaattgttc cttcccttct
    37141 tctgttaatt cataaacttt cttttccaat ttttcacctg tgatctctac ttgatgctga
    37201 atgattcctt gctcttccat ttttgcaagt tcaggataaa tctgactatg ttttgcttgc
    37261 caaaattctc ctatttcatt tttgaacgat tgattcaatt catatcctgt catcttcttc
    37321 ttacttaata accctaacaa aatatatcga agtgtatttt ttcttgccat cagttttccc
    37381 tccttgacaa atctttaaat ccattctatc ataaatgagt aatcgaaaac atgtagttta
    37441 ttacatgttt taatttataa ggagatgctt aaacatgaaa gaatttaaag aattggaaga
    37501 ttttattgga actcacttta tctatacgta tgacaatggt tgggaatatg aatggtatgc
    37561 caaaaatgac catactgttg attaccgtat ccatggcgga atggtcaaag gccgttgggt
    37621 aaaagaccaa gaagctgata tcgttaaatt gacggacggc gtattcaaaa tcacttggac
    37681 agagccaaca gggacagacg tggcattgga ctttatgcca aatgaaaaga aacttcacgg
    37741 aatgatcttt ttccctaaat gggttgaaga acatccagaa atcactgtta ctttccaaaa
    37801 cgaacatatc gcagaaatgg aagcagctcg tgaaaaatat gaaacttatc caaaattact
    37861 tgttcctgaa tttgctacga tcacttatat gggtgatgca ggtatagaca atgaagatgt
    37921 tattagcgaa gaaccatacg atggaatgcc agatgatatc cgtagcggaa aatacttcga
    37981 tgaaaattat aaacgagtaa aataaggttg tgaaagagag gttgtgaaat cagcgttctg
    38041 acctgagtat tagagaaaga aacggaaaaa tagttcctca tgttttgccg ttttttgagc
    38101 taataccgag ggtcagctga ttgaacaccg tttatcaaga ggttgtgaaa tcagcgttat
    38161 gctttgagta ataagaacgc tagttagaaa atagcttttc atattttcta ggctagtggg
    38221 cttattaccg agaagcagcc gtttgaacac cgtttatcaa gaggttgtga aatcagcgtt
    38281 ttgacctgag tattagagaa acaaatggaa aaatagttcc tcatattttg ccgttttttg
    38341 agctaatacc gagggtcagc tgattgaaca ccgtttatca aagattgtaa caactgcata
    38401 ttcacacagt taaattagtg acttcaaaat gaaataatgc tcccagcaaa aaattaggct
    38461 gggagcatta tttcgttatt ctgttcatca aaaatcagcg ttttgattcc atttcatcac
    38521 aagttcctcc tcatttactg cttcatcttt ttgctgtgtt tgaattgtaa aaccttgtga
    38581 aagatagaaa tgaatagctg attgattttt ttgatagact gtcaaagtca gtgttttatt
    38641 ggtttctttt atttttttca ttagttgcgt accgattctt tgttgccggt attccctttt
    38701 cacaaagatt cctgcgataa actgatcaat caccccagca aaaccaataa tttcttgatc
    38761 tatttctgct aagtaaatca ctgcatctgg taaagctttc ctaacagatt ctacttgatt
    38821 ctcccaataa gttgatggaa tgaattcatg agaatccaag ttagcatgca gccaaatcga
    38881 tagaacagat tccagttctt tggcagacaa ttttgttgtt gtgcggatca ttttttctct
    38941 ccttacttat tcattgattt taaaataaaa accatttttt tgaagctctt ttacaagttt
    39001 tcgcccctca aaaaagtata tcttctcttg ttttactttt ctaataccaa aagaaacagc
    39061 aactttagga tcatcagctg aaacgattcg ataagttcca ccaggcaatt gatccagctt
    39121 gactttccca tgatggtcgc tttgtactga aaacggcaca ccatttctag taagtgtttt
    39181 tttcttatgt ttcaaaatga atgaactacc atttaccggt ttccctgacg aatcactaat
    39241 aataaatgaa aaatcaagca cttttttact taatctatac tgatagatta gtcgtccgat
    39301 aaacactaac agtatgacta cagctattat cgttcctgca agaataaacc attgccgcat
    39361 ggttctttcc tgatttcctt ttccttcttc tttttttacc gattcgttat aaggaatccg
    39421 atgtcctgtc actagcaaac gatgcgtgtt gatcatatac ggcgtacatg taagcaaggt
    39481 aactaagtct tctccttctg aaatcgttag aacagacgtg tcatctggca gtaccacttg
    39541 tatattttta acttgataag ccaatttctc ccccaaaaca gtcaaaataa acgtgtctcc
    39601 gttttctaaa cgatctaatt cggtaaataa ccgtcgatta ggtaaaccgc tgtgagcaga
    39661 gatcactgaa tgcgtcgaat ttccaccaag cgggaaagag gttccttgca agacgcctgc
    39721 tccattttca aggatcctac cattgagccg atcataaagt gaaatattta attggatctt
    39781 aggtatattg atacttccga tcagccattc ctctaattgg ctggatgttg tactttcatt
    39841 tctgttcttt tcattgaaag gatcagtacc aggattgaat ccttggtcag ttaatcgttg
    39901 ttttttctcc tccattttct ttcgctgcac ttcaatttca gctgcggtcc gtttttgtac
    39961 ttgttcgata cgtttttgat caataaaact atttaaagaa tccacataaa atggatataa
    40021 agcgatcagt aaccctacga cgatacatat taataaaaac aaacgaaaca aaagtcgacg
    40081 agactgtttt tgcttactct gcttcacatg tgtcctccct tgcaagtttt tttgttcttt
    40141 cttttattat atgggttcag gaaaaaaata gaaaatgaaa gccgatgagg ttgtgaaaaa
    40201 gctgtcctgc atcaagtaat aagtacagcc caaaaaaata gctactcata ttttttgttg
    40261 ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa
    40321 aactgcgtta tgctttgagt aataagagcg ctagtcagaa aacagcttct catattttct
    40381 aggctagtga gcttattacc gagaagcagc tgattgaaca ccgtttaccg agaggtcatg
    40441 aaaaagctac tttgtttcga gtattaagaa aaattctgtt tcaaaacaag gagatgcaac
    40501 aaaacttatg tcgcatcctc tctccttaga actttcactt atgtttttct tgtaaaattc
    40561 ataaatattt tcatgaattt tctaatttct tgcctacctc tcgcatagga tatatgatga
    40621 atttatctaa agtttgcaaa ggagttcgac aattgaaaaa atatggccca tttttagcaa
    40681 tttttttcat tgctttggca tttctcatgc ctcatttatt cacacataaa ctaattttgg
    40741 gtgctgatgc cccattccat tacaatcggt tctatgatgc cgcgcaacaa attaaatatg
    40801 gggatttcca ttattttcct tccctttatg gattccagca aagtggcagg atcgtgaatg
    40861 ccgtttacgg cccatttttc gcttatttac aaggattgat cgtgttgctt gcaggtagct
    40921 ggtttcatta tcagattctt tcaaatttca ttctttatct tatttcagga ttttctatgc
    40981 tgattttact gagatatgtc aatgttcgaa attgggtaag tgtaccagta gccgttttat
    41041 tcatgagtac gtattctatt caatactggt ctatcaacca aggattcact agctggggga
    41101 cttgttttta tcctttatgt atgatcccta ttgctgattt cgtccttcat aaaaagttcc
    41161 ctgttatcaa agtcgctgtc tcagtgggac ttatgacaca gatccattta ctgtcttcga
    41221 tcatgttagc tttgatgtat atcccttttt atctttatta cttttttaac cagactgaaa
    41281 aaggaaaagc actgcttcaa ctgattaagt cggtcttgct ttattttgtt ctgacagcaa
    41341 atatttgggc aggattagct attgtttaca gtgggaataa gattcttcct ccctttgtta
    41401 acagagaaat gagtcaaaag gcgatagatc tggatggcag ttattggctc cattacccta
    41461 aggcctttcc tatattgata ttatcaggtt ttttgctttt tattttcttt caacaaaaga
    41521 acaccttatt ccaaaaaatc gtgttgtaca caagtcttgt tttctttttt ctttctacta
    41581 gcttgattcc atggacgaca ttgatcgaaa aaaatgtgcc ttttattagt ttgatccagt
    41641 ttccatttcg atttttcgtg ccatttacgc tattgcttct actttacctt gccctttcac
    41701 tgaaccagtg gtctgaacaa aagtggttcc gtcttttaag tatatttggc attcttattt
    41761 tttcagcaca gacgatccag aacttatacc agcatctgga aaagtgggaa aatgaaacat
    41821 ttgtcagtcg acatacttat ctattcgata cgccggaaga agcaaggaaa acattcttca
    41881 gcaaagatat gtctaccagc ttgttcgttt tccaaaaaac cacacctgac tatctgccaa
    41941 tctataagga gacaaaagac aataaatacg accggtataa cgaagaaata ctagaaaacg
    42001 aaacaacttt tataaaaaca catccaggcg gtcttttgac aatcaagtgg aaaaacactg
    42061 gggacaaaac tgttcatatc cctgttatcg tctacgatcg gactgtgcta cagcaaaatg
    42121 gaaaaacatt gactgattat gaagtaacag atatcgggac cccaatcgtg aagcagaaaa
    42181 aaggaatcaa cgagctcacg cttcattatc aaacgccaat ctatttctat ttcattcttt
    42241 ctcttacttt gattggctgg tttaccttgc tatgtttatt tatttatcat agatacaagc
    42301 ttttacgtgc ttaggcaaaa gggataaata catccgatca aaaaactctc caaacggtat
    42361 aatcgtttgg agagttttat tttaatcagt ttttttatgt tatatgttat attttttatt
    42421 cgttcacatc taattcgatt tccaccccgt agtgatcact gatgattgga ctatcgatcc
    42481 catcaaaaat ccgttgatat tttttaacct gcattccttc agggacgaaa ataaaatcta
    42541 tacgcaattt ttctgtattt tgttcccaac catctatttt cttttccaca gtagctgctt
    42601 ttcctttttc attcgcgaca acatacgaat cttgaagaag aaggcaactt tctcttacag
    42661 tataataacc ttgagagtct actggattat tgaaatcacc taggaaaaaa agtggtacgc
    42721 gagtttccaa aaagtagttt tccaagtttt tccactcaaa ataaaagcca ctttttttat
    42781 ctgtccacca agaaaagtgg cagctcgaga caaaaatgtc ctgatcatct atctttgttt
    42841 tcccaatcaa gatcttgcgt gtctgataat cttctttctt ttgagattgg gagacggtaa
    42901 ggacctgact ttccaatgtt tttttcgtaa gcagtgcatt tccttcttca tatttatcat
    42961 aaccgatgtg gctcatttcc caactccaaa aatactcttt tccgtgttcc tttaaaagct
    43021 gaactaaacg gtaggcaaaa ttatctttac ggataggtac ttgattcttt acctgacaga
    43081 acttcattag cttcgcaggt tctacttctt cagattccag taattggttg atttcttgta
    43141 aagcaatcac ttcataatct tctaacagga tcttatctgc taattcttgc aattttttct
    43201 ctggttctgg ctcaagccag ctatgcgtgt tgagtgtcat gaatttcatt ggttttctcc
    43261 ttgtcttcat ttcgaaacaa aagggttgtg acaaaatttt tgtcacaacc tctccagcaa
    43321 atagtgttct cctgctaact cctcagtaat aagctcaatg gaccaggagc tattttttgt
    43381 ttggctgttt ttatcacttg gtgcagggca gctttttcac gacctctcca ctaaacagta
    43441 ttcaaactgc tgcttctcgg taataagccc aaccaaacga aaaataggag gagctatttt
    43501 tgtttggctg ttcttatgac ttgatgcagg acagcttttt cacaacctct ccttacattt
    43561 taatggagcc gatcacttta ccagctgtca ctgtacctaa ttgcttgatc actacttctt
    43621 ctactttatc gtttgtaaat acgatcatga tcgttggatc tttttcttcg ttttggatca
    43681 catcaagatc catctcagct aatttcgttc ctgttcctac ttcttggcct tctttgacag
    43741 caatctcaaa agctggctga ttcatttgga ctgtatcgat tcccatatgg atcaaaactt
    43801 cgataccatc tttcgtttcc agcccaattg catgtttgct agggaaaata cttgtcactt
    43861 ttccagcgat cggcgcaaca acttctcttg atgttggaat aacagcaaag ccgtcaccca
    43921 tcattttttg tgagaatacc ggatctttta cttcagataa aggaatcact tctccagaag
    43981 ctgcggaaac tagttcttgt tctataccta agtattgctt actacctgct tgtccatttc
    44041 ctgtagaaac catttctggc tctggaatct ctgctcctga ttgcagcaga tcttcgatat
    44101 ctgatttcaa gacatctgct tttggtccat aaactgcttg gactccattg tctttgacga
    44161 tcaatcccat cgcccctgct cgtttccagg cttcttcagt ccctactttt tctcgatcat
    44221 ttacacttac gcgtaaccga gtcatacaag catcgacatc tttgatattt tcttttcctc
    44281 ccagcaaatg aatgatctgg accacttgct gatctgctgt tcctgttccg ctgttagata
    44341 caacggtttc ttcactgtca ttgtcgtaat ttccgttacg tcccggtgta gcaaagttga
    44401 attttttgat caagaaattt gctaagaaat acgtaacaac accaaaagcg atcacacaca
    44461 acacgaagtt gataagatct ccacctagac ccgctttgat agctaacggt gtccgagtca
    44521 gcaattcgat attcccaaat gaatggaccc gcaatggcaa gatatctgcc atcgcaaatg
    44581 cagccccttg gatcactgaa taaatgacat ataatggcac agcagcaaac ataaacatga
    44641 actccaatgg ttctgttaca cctgttagaa agacagccaa cgctgctgaa aaatacattg
    44701 atttatatct tgctttctta tcaggatcga cattacgata catcgcaaaa gccattccca
    44761 tcaagatacc tgaagaacca atcatttgtc ctactttgaa acgagccggc gtccagttat
    44821 gcaacacaaa ctcatattgc gacatatccc ctgcaccttt aagattcact aaatcagtgg
    44881 cccaagccaa ccataacgga tcttgcccaa atacttgtgt ccccgcctgt gcgcctgata
    44941 aaatctcata cgatccgcca agctgtgtat agttgatagg aatcgtcagc atatgatgca
    45001 atccaaatgg caatagtaaa cgttctaatg ttccaaataa aaacggtgct agaatcggtg
    45061 cgctttcttg tgattctgca atccataaac caaaattatt gattccagcc tgtacgtttg
    45121 gccacaccac agcaagaatc aatgccacga ttgttgacca taagataaca acaaacggaa
    45181 caaagcgctt tccattgaaa aatgacaaag catccggcaa ttttctataa ttatagtact
    45241 tattataagc cattgccccg acaaatccag cgatgatccc tacgaatact cccatattca
    45301 aagctggtgc ttccaataca cttgtaaaaa atcctttaac catgatcttc gtaccgaaca
    45361 gagtgtgggt aaatgcatct tcattcgcaa gcatgtcact tgtgacacca aagatagccc
    45421 cagtgatccg attgattaaa ataaatgaga tcccagctgc aaatgctccg cctgctcttt
    45481 cttttgccca acttcctcct attgctaaag caaataaaat atgaagatta ccaataattg
    45541 cccaaccaat attttcaatt actccgcccg ttgtgacaag cggcgtccaa tcaggattga
    45601 tcaagggaat tgatttccct atactgatca tcaacccagc tgccggcata actgctacca
    45661 caaccattaa agcctttcca aatttttgcc aaaactcaaa actaaatatc tttttcattc
    45721 cgtttagctc ctttacgcaa tcggtttcgt taaacgtatt atagcgtgcg ttttcttttt
    45781 tgtaaatgct ttatttttta tttttctgtc tataccattc tataaaacct ataatacgtg
    45841 tgttcccttc tataattttc tcctaaaaat ttattttttt aagctttttt ctatgaaata
    45901 ttttcttttg tctattgact tgtgcaatcg gttgcgttta ttatgaacgt ataaaacagc
    45961 tcattaggag gagaaaaatg aaacagatca aacgactatt tgctattgat ccatggaaaa
    46021 tcagcacgac acaattagat aaaaaaaatc ttcgactgca agaatcttta acaagtattg
    46081 gaaacggtta tatggggatg cgcgggaact ttgaagaaac ttactcaggg gaccaccatc
    46141 aaggtactta tttggcgggt gtctggtatc ccgataagac acgtgtcggc tggtggaaaa
    46201 atggttatcc agaatacttt ggaaaagtga tcaacgcctt gaactttatc gcgatagata
    46261 tttcgatcaa cgatcagctg atcgacttgg cttctttgga accagaagac ttttactggg
    46321 aattagatat gaaaaatggt gtattatctc gtacattcac aatcactact tctactaata
    46381 aagtacgcat ttccttcgaa cgttttctga gcattgtcaa aaaagaatca gcttatatct
    46441 atttaactat agaaatgctt gaaggtagcg gaacagtcaa actcgtatca aaattggatg
    46501 gaaatgttca aaacgaagac agcaactatg atgaacattt ttggaatgag attgatcgtg
    46561 gaactataga agaaatcggc tatttgacga ctaaaactat tccaaacaac tttgggattg
    46621 aacaatttac tgttactgca gcaatgcgcc atttcgttaa tggaaaatca gtcatccctg
    46681 actatcacga agatacttta gcattacatg gttgcttgtc tgcagaatta tctcaaggtg
    46741 agacatggtc agtggaaaaa gaaattatcg ttcttactag tagagatatt ccagaagcgc
    46801 agcaagcaga aaaagctgtc tcagaattaa cgaaccagac aaacaattat atccaagcaa
    46861 aagaagagca aacagcggct tgggcagaac gatggaagct tgccgatgtg gtcatcgaag
    46921 gagacgaaga agcacaacaa ggtattcgat tcaatttgtt ccaactattc tctacttact
    46981 acggcgaaga tgaacgattg aatatcggcc ccaaaggatt cacaggagaa aaatacggcg
    47041 gagccactta ctgggataca gaagcgtatg ctgtccctct ttatcttgct ttagccaaac
    47101 ctgaagtaac taagaatctg ctgaaatatc ggcataatca actgccgcaa gcaatccaca
    47161 acgctcagca acaaggatta aaaggcgcgc tttatcctat ggtcaccttc actggtgtcg
    47221 aatgccataa cgagtgggaa atcacattcg aggagattca ccgaaatggc gcgattgcct
    47281 atgcaatcta caattatacg aattacaccg gcgatacgga atatttgaaa aatgaaggac
    47341 tggaagtttt agcagaaatc gcacgcttct gggcagaccg tgtccatttt tcaaaacgag
    47401 caaataaata catgatccac ggtgtgaccg gcccaaacga atatgagaac aatatcaata
    47461 acaattggta tacaaatacg atcgcagctt gggtcttgcg ttacacgcga gaaaattatt
    47521 taacttatca aaaagaagct gctatcacta tcagcgaaga agaactagcc aaatggaaag
    47581 atatcgcaga gaacatgtac ttcccagttg acgaagaatt aggaatcttt gtccagcatg
    47641 acacattctt agataaagat ctcatgcctg tatccgatat tcccacaagc gatcttcctc
    47701 tgaatcagca ttggtcttgg gacaaaatcc ttagatcttg cttcatcaag caggcagatg
    47761 tactacaggg gatttatttc ttcaatgata cttttacaaa agaagaaaag caaaaaaact
    47821 ttgatttcta tgaaccaatg actgtccatg agtcttccct ttcgccaagt atccattcga
    47881 ttttagcagc agaattagga atggaaagca aagctgtaga aatgtaccag cgaacagctc
    47941 gcttggattt ggataattac aataacgaca cagaagacgg cttgcacatc acttccatga
    48001 ctggtagctg gttgtcgatt gtccaaggat ttgctcaaat gaaaactgcc catgatcagt
    48061 tgagattcgc accatttctg ccaaaaactt ggaaagctta ttctttccat atcaattatc
    48121 gcggacgttt attgttcatc tcagtcacag atgaacaagt tactttcgag ttattagaag
    48181 gttttcctct agaaatttac gtctatgaac agtcttattc tttagcggat cgtctagaaa
    48241 taacgctaag aaaggaggaa gcaaatgttt aaaggggtat tgtttgattt agacggtgtc
    48301 attaccgata ctgctgaatt ccattatcgt gcttggcgaa agcttggtca ggaaatcggc
    48361 attacgatcg accacacatt caacgaacag ctaaaaggcg tcagccgaga agactcactc
    48421 tctttgcttt tagcttatgg cggaaaagaa cactcttttt caaaggaaga atttgcagaa
    48481 ttagcgaaaa gaaaaaacga ttattattta gagatgatcc agacgatcga accaaaagat
    48541 gtcttccccg gggtcgtgcc tttactggat tctttaaaag aagaaaaaat caagattgct
    48601 cttgcttctg caagtaaaaa cgggccattc ctacttgaaa aaatgggtct tacaccttac
    48661 tttgatgcta ttgccgaccc ggcagaagca acaaacggaa aacctgcgcc agatatcttc
    48721 ctccttgcag caaaagctgt cggactaaaa gcagaagaat gtatcgggat cgaagacgcg
    48781 caagccggta tccaagccat cctctcaagt ggcgctcaac caattggcgt gggacgtgct
    48841 gaagaccttg gagaggagat cccgcttgtc cctgatacga cttttcttac gatcgattac
    48901 ttgaaagaaa agtgtcatga ccatggataa tccagagatc tccgtcgtac cagttccaga
    48961 gactgaaata aagaaaatca cattgaagaa cgactactta gaagtcgttc ttctcaatta
    49021 cggtgcccgc ctgcaccaaa tcttcgcacc agacaaagaa ggaaaatcag aaaatgtttt
    49081 attgtcttac gatcgtttcg aagatgttct aacagacaaa agcttttttg gagcaactgt
    49141 cggacctgta gccggaagga tccgggatgc ttcttggggt gagcatagat tggagaaaaa
    49201 ctgcggatca caccatatcc acggtggcac gaaaggctgg tctttccaat tttgggaagt
    49261 agaagttttc aaaactccat catcaatagg tgtggtcttt tacttaaaag atgaattttc
    49321 tacctatcca ggaccaatca ctgctacgat cacttaccgt ttaacaaaaa acgaattaga
    49381 gatgacaacc tctgctagta gccttgttga aaccatctgc aatccgacca accatgccta
    49441 cttcaacctt tcaggaaatg gaacaagaga catctatgaa catcagttaa cggtcttttt
    49501 agatggtgtg cttgaattag atcaagaaaa actgcctact ggaaattgga caaaaaaaga
    49561 aaaactgcca atcgacttta gaaaatcccc aacactgcaa gagatccttg catgttatcc
    49621 agatggacta gatgatgtat ttcttttgca tcatcctagg ctttccaaaa cttccttaca
    49681 attattcgag aagcattctg gtcgccaaat gactatagca acttctaata aaagtatggt
    49741 attattttct acgactggat tcgaagctga tttctctgtc aatggaaaac agatgcattc
    49801 aaactacgga ttagcaatcg aaccgcaaga aatccctgat atcgttcatt tccccaaatt
    49861 tggatcgatc aacctccatc ctggtcaaga acggatcagt cagacgattt atcggttctc
    49921 tgcacaataa caagagaaag gtgtttttat catggctatt accgtaaaag atgtggcgaa
    49981 aaaagccggt gttgccacct cgaccgtctc tcgtgtcatc aacgatcatc ctagtatttc
    50041 cgagacaaca aagaagaaag tccgaaaaat tatggatgaa ctaggttatg ttcctaacat
    50101 gactgcccgc aatctaggaa aacgcatttc cagtgccatc ggcgtaatct taccccctct
    50161 tgattcaaaa gagcggatcg gtaacccatt ttatcttgag atcatggaag caatcaacga
    50221 agaagcgcgg aattatgata tgactacagc aatcgctact gctaaaaatt ttgaattgct
    50281 gttagagaac gtccagcgta tgcatttaca aaaacaagta gatggtttta ttctagtgta
    50341 ttcagatagt caagatcctg tcattgatta tttataccaa aaccacatcc ctttcacttt
    50401 gatcggacag ccttatcatc atgagaacga aatcgtttat gtagataatg ataaccagct
    50461 tctaggtaaa caagcaacag aatttttgat ccagaatgga cataagaata tcctgtttgt
    50521 gacaaacacg actcatgaaa gtttgtattt cgaacgatat ttcggttatc aaaaagcaat
    50581 gatgatggct ggtcttcctg cgttatccag tgtagtacta gagcatccgg aggattatct
    50641 gtcctttgag aaaacgttga aagaaaacga agccacagca ttggtggtca ttgacgatat
    50701 cttcgccctt cgcacgatgc agttggcgca aatgtacggc tatgtcattc cagagacact
    50761 ctccgtcatt agcttcaaca actcgatctt ctcaacatta acacaccctt accttacaag
    50821 tatcgatatc gatatctccg aattaggacg tgtcgctatg caaaagctgc gcgaattgat
    50881 ccatgaagaa ttgagcagtg gcgtacgttt ggtcatccct catcgcttga tcaaaagaga
    50941 gacagtcgtt cctttagaaa acccatacta aatagctgac tcactaaata cgctgaccat
    51001 ttatcctatg gtcagctttt tatgtaaaag aagatactac ttctaacaca ttgtttatct
    51061 gtaaaaaaga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    51121 aaacggcgga agcagaagca actccttcgg aaataagctg aaattcacaa aaatttaaaa
    51181 agcaattttc ttgagtttct tcttatttct tggagttaaa cgcttctgtc ccagcctctt
    51241 ttttccttcc ttcaattttt tacacgtcga cgattcaata aaaaaccgcc taatattgta
    51301 aagacaggtg caagaatcga gaaaaagacg aatggcaagt aatgcaacgc gctaactttc
    51361 atcgttccca taatgaatgt gccgctgact ccccacggta cgagagaatt gacggtcgca
    51421 cctgaatccg ctagtgttcg tgtcaaatag gtttttgata agccaacgtc atcaaaagaa
    51481 cgcttgaatg tttctcctgg aagaatgatg gacagatact gttctccaac gatcagattg
    51541 attccgatac agctcaaggc agtaaacccg actaaacgag aaggtcggtc catcttttct
    51601 tttaattctt gaacgatggt atcaacgatc agatatttga tcagtaaccc acctaatgcc
    51661 aatgcaagta aaatcaaact agcagaacct aacatactca tgatcccgcc tcgagaaagc
    51721 agttcatcta gctttggatc aggtgtattt gcgacataac cattcatcaa gatgtctgct
    51781 gcttttccga ccgtcaaact tttctcatgg ataaaagaaa gaacgagagc agctgtcgat
    51841 cccgctagta atgtagggat agccggaatt tttttgattg cccccccaaa taaaataact
    51901 agtggaatca atgtccaagg agagatccaa aagctcgctt tcatgttttg gatcatttca
    51961 ttgatactag ctagatcggc tgaatgactg ttatgtccta atatcgtata aaaaatcaac
    52021 gaaaggacga atgctgggaa atccgtataa cgcataccag cgatatgttc gaatagatta
    52081 actcctccaa tacccgctgc caagttggtc gtatctgata aaggcgagca gttattccct
    52141 aaaaaggcac cggaaacgac tgcgcctgta gtcattgcat cattgaatcc aagtaaatga
    52201 ccgatcccca aaaaagcaat tccaatcgtc gaaatcgttg taaatgaact gccgacagtc
    52261 actccgacaa ttgcacaaac aagaaatgct gtcggtaaaa agaaacgcac agaaacaagt
    52321 ttaaatccat aaaccataat cgtagggatg gttccagata aaatccatga agcaactaag
    52381 acaccaatca aaagaaaaat caggattgga atgatccctg gagtgattcc tttgatgatc
    52441 ccgtcatgga tctcatccca tgtgaacttt ttaaatctgc cataaaacaa caaacacatg
    52501 aaagctgcaa ggatcgggat atgtggcgag agctggaatc cgatgatcag tactcctagg
    52561 agtgccaaca acacgatcaa tacagcgata ctttctttta aagaaatatt tttattcatc
    52621 gtcgatctcc tatttcaaat gaaaaggccc tgccatgaaa aaactattca cttggcagga
    52681 cctcctacta aatcagcgac aaaacgtcgg ctgaaagact tatttttttt atttttcttc
    52741 taaacttttt tctacctcaa tcccccaaga atctttcttg aagtgattga tgatcaatgg
    52801 aataacgaac atgaccactg tgatagctgc tactaataat gcatcactca atgtcgctgt
    52861 acctaatgta gcaaatacga caacgatgat agagaagatc agcatgcagc tgactaccca
    52921 agctaatccg tttccgtttt taccaattcg gtaaggacgt tcgaattctg gatgtttctt
    52981 acgcatttta agcaatgaaa cagcaatcaa aatgtacacg atacaataaa taacagttgt
    53041 agcatttgta agtgtcaaga atacagcact tacgtcatcc attacaccat aaagcaaagc
    53101 aaataatgaa ataacgattg attgtgttag aacgacattt ctagatacgc cgtatttgtt
    53161 ttctttatgg aatccgaatt ttggtggaag gaatccttca cgagctactt ggatgattgt
    53221 ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc acaccaataa ataccatgaa
    53281 gctgaagata tttccgatca cttctggtaa gcctaggatt tgacagtcaa tcaagatagg
    53341 ctgcgtgata tttgctaatt ccatttttcc atctggtacg acatttgcta caagcatcgc
    53401 attgatgaca ttcaataaaa ctaatccgat caaagcgata aatacgcctt ttgtataatt
    53461 ttttgttgcg tctttcaaac gaggcatgta aacagaactc atttcgatcc caacaaaaat
    53521 aaatgtgata ccagctaagt atttcaatga atcaatatgt tccaagtcag ggaaagcttt
    53581 tgaccatgaa aagtcaccta gatagccgtt tgagactagt ccgactttga aggctgccaa
    53641 aacacctaaa acgaacatga tgactactgg gatatatacc cctagccata caccgatgtt
    53701 cccgccgact tttgccatat cgaatttcaa gttcaagatc gtgatgatcc agtagataac
    53761 taaaatacaa cctaaaacga accagtgatt attgccaagt tctacattac caaatgtgtt
    53821 tcctaacaat ggtcctaaag tagaagcgac cattaccata cctgggaaca tttgcaccca
    53881 taatagccat gcaacgacaa atccccattt gctgcccagt gctgttttta cccataactg
    53941 aggaccgcct tcttgaggaa gcatcgtgga aagctcaccg gaaaccattg atatcggacc
    54001 ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat gtccaaccga ctgcggctaa
    54061 cgtaggaata ctccgaaccg ttgcacacag tgccattgtc agaccgataa aggtcccaag
    54121 acccatttta cttacttcag atttactcac cgttgacact ctccttgatt ttttggataa
    54181 aataacggtg tctttgaagt agtttcagca ataaacgaaa caattcagcg aatatttgag
    54241 gggattcttt gagtctattg cttgaagggt ttcttcaaag acaacctcaa aacaaaggga
    54301 tcgaagagct taggtctccc cttgctcttc agatccaaac atgcgtcaga aacagttagt
    54361 attcaagctg ttttctaaca tgattacctt gcttattttg cttcgcttgc caataattgg
    54421 tctgcgtaga ttttttccaa tttttcttga agagctgctt tgattttttc agcatattct
    54481 tcaaagtgtt cttctttgtt catgtatggt gtcattacgc tggcacgcaa tacagttact
    54541 tttccggcac ggttccattc ttcatctgag aatcctagtt ggttcacaaa ttgtaatggg
    54601 ctgttgccat agtctgggat agcaaagtca gtatgtgaag ttaagaactc attaccgtaa
    54661 atgcttcctt tcacgtatga agaataatca tatacgtcat ggttcaattt attcattgca
    54721 actaagtcat cgttgccttt ttctttgaat acatagtcta ccatattgaa atctggataa
    54781 gttaatggat gaacttcgat ttctttgtct cctactttaa atgacaagtc attcaagaag
    54841 ttgtagaaac gatgtgcacc ttcgattgat gcacccatta atttaccata tcctgtgaca
    54901 ttcaaaggta agacatggtg tgctgcccaa acgctggctg ctgttgcccc tgcttttgaa
    54961 ccttccaaga tataagcccc aagtaatgct gggatatctg cgcctttttc aaatacatat
    55021 gtcgcaaagt aagagataac gtctctcatg cggatatctt tgatgacgat accaccggca
    55081 gaatatggaa catagcccat tttatgtggg tcaatcgtta cagattctgc ttcttcgatt
    55141 gctttatatg cactgtgtac ttcttctaag atataatctt tgttttctgt aaagacattg
    55201 tatttgtaat gaacatcttt taaatcttca aatggaatga agttgttgtc ttcgtctaag
    55261 aaaatcgcac ggccgtatcc gccataagca gcatctacgt gtaagtagaa gtaaataccg
    55321 tctttttcta atacgcgacg caatgcaacg attttatcga taccgtcgat tgctccttct
    55381 tctgttgatc ctacaacacc gactacacct aggattggtg ttttttcagc tgctagacca
    55441 cgaacgattt tttcaagttc gttgatgtcc atgcgatagt tgtggtcaac tggcactgga
    55501 atcacttggt ctaaaccgat accgatgatg tcggcagctt ttagccatga atagtgttta
    55561 gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt ttccgctacg tgctgagtga
    55621 gctttgattt cgtcgatttt ttctgggacg ctgtctaaca gattcatgat ttcttctgtt
    55681 gacaagttca ttaattccca atcgcttttt ccagcaacta gttcaggtgt cacttctttc
    55741 attgcaagcg gcaatgattt gatgttgcgg gcataccaaa gtccttctaa gtttgctaaa
    55801 gaaccatcag caacgatgtg gccccagcca tctttatagc tcattaattt tgcaaattcc
    55861 attcctactt cttcttccat ttggcttgtt gcaggagaag attcataggc aacgttatta
    55921 ccattccata gcatagcaaa attgtacgct agtaaagatg gcatcaatgt ttcagagttc
    55981 atatgacccc agtaacgtcc ggcattatgc caaggaacgg aatgggtacg catccgcgct
    56041 gaaatttctg atagaacatc ctttgtttta ttcacagtgt gttcaaaact agcactgctt
    56101 ttttcttctg gcgtaataat aggcatgtct tgaggcatgt agttttgacg ccagcctaaa
    56161 tgttcatcca ccaattcatt caacaaagct ttatagattt ggccgttctc agctttgtcc
    56221 ccaatgaata gggcatttag gtttagatct ttcgacaatg attcactcat agtgaaaccc
    56281 tcctaaaaaa atatttaaat tttgtcgagc cctacattac acctgttctt ctattctgta
    56341 aactaagttt tggcctgatt tttaatcata ttttaatatg tatcaattat ccgaattgtt
    56401 cacacttttg aaataattaa aaaaaacgag ggaatttaca aatgtaaact ccctcgcaaa
    56461 gattgtatta acgacaacca gcgttctatt ttaggatggg tttcaaaatt ggaatgttgt
    56521 aatagtattt ccctttttca aggtaaaaac ttactaaatt ctaatcaatt actttggcca
    56581 aaaagtaatt tttcttacct tttcgaataa ccacaaactt accatcgaat tcatcggatg
    56641 gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt aatacttata gctccgtttg
    56701 aaacatcttc acgtgcttga cgtttagatg gttcaatttt tgtggaaaca agcagttcca
    56761 cgatattttc aggtgtgctt gaaatttcaa cgttcggcat tttaccgaat ccttgcgcga
    56821 tttcttccgc atttagttct ttaatatttc cagagaacaa tgcttgcgtt attttttgcg
    56881 cttctttcaa gtcttcttca ctatgcacaa atcttgtaac ttcttctgcc aaacggcgtt
    56941 gtgcttcacg tttctcaggt tctgtctcta cttttttcgc taagtcttcg atttcttctt
    57001 gagacaagaa agtaaagaat ttcaagtatt tcactacatc gcgatcatct tgattcaacc
    57061 agaattggta gaactcaaat ggtgaagttt tcttcggatc aagccaaacg gcaccgcctg
    57121 cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa tgggatcgtt aaaccgaacg
    57181 cttctacttc tggtccttct aattttcgga ttaggtctaa tccagctgtg atatttcccc
    57241 attggtctgc tccaccgatt tgcaattgca catcgtatgt tttatgcaga tgcaaaaagt
    57301 cgatagattg cagaatttgg taagtaaact ctgtaaatga gattcctact tccaaacggc
    57361 tggcaacgat atcttttgct aacatcgtgt tgatgttgaa gtttttaccg tagtctctca
    57421 aaaattcaag taaagagatt tttgacaacc agtcgtagtt gttcacaaat gtgatatttg
    57481 catctttacc aaacaatttt ctcatttgat tggaaagtgc gtccacgtta tgttgcactt
    57541 gttccatcgt ttgcaacaca cgttctgttt tgcggccgct tgggtcgccg atcgttcctg
    57601 ttccgccgcc aatcagaata tatggatgat ggcctgccaa ttggaatctt ttcatcatca
    57661 taaatggaat caaatgtccg atatgcatcg aatcaccagt tggatcaacg ccgcaataaa
    57721 gtgaaatgct cttttcttca acgagctcgc gaagtctttc ttcgtttgtt tgctgattaa
    57781 tggcgtcgcg ccaagttaat tcatcaataa tattcatttt actgacctcc gtgtagtttt
    57841 tttatgaaag caggaacctg ctagcatgtg taattaatta tttcttcagg ataggatagg
    57901 aaataaaaaa agtcccttgg catataagcc aagggacgaa atctcgcggt accacccaat
    57961 ttgtatgtct agatatccaa catacctctc gaacatttaa cgctgtcgcg tggcaatcac
    58021 tgccaaagac tcctgaaatg taattcgctt taaagcatgt actggtttgc agcgaccacc
    58081 agctttctga aacattggct ttaacaacta cttcgtttcg atcttcgtct tgttattatt
    58141 aatatgtgtc tatcatagag cgcaactttt tctttgtcaa cagaaaaagg atattttttt
    58201 taaattcctc attttttctt ttttgaatcc gctctaattc cgaacatttt attttcaatt
    58261 attgttaaaa gaaataactt tttctgtatt ttttctgcaa tttatcgaga agtcacttta
    58321 ctttgcctct tattctttct tcgttacaat aaggaatggg acaagtaaaa aaatgaaaaa
    58381 gcaagggacg aggtatatgg aaaaaaagca aaaaattatt ttaggagcca cttctgcttt
    58441 aactatcgtt attttaattc taagtttgtt ttttgtcatc cgatcatcta caaaaaaaga
    58501 accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa gaaccgacag atgataagca
    58561 acaactagtt actcaagcaa aaaatctggc tcaaagctac gattatgacc aagcgattgc
    58621 gttattggaa aaagatagta agaacggatc tactgaaaca caacagcttc ttcaaacact
    58681 aaaaaaggag aaagaacaac tgatcgactg gtctgatcct actcagatct ctcatgtctt
    58741 tttccacagc ttgatcgtgg acccgcaaaa agccttccac tctcaacagg cacaaggata
    58801 caaagattat atggtgactg ttgaagaatt caaccgttcg atcgaacaac tttatcaaaa
    58861 tgattttgtt ttagttaatt taaatgattt gatccaaaaa gacgaacaag gaaatctttc
    58921 ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg gttctttcac aagatgatgt
    58981 cagctattat gaatatatgg ataattccgg ttttcctagc cgattggtcg tatcaaataa
    59041 caatgaaatc aaaaatgtct ataaagagaa agataaagaa gaaatcggtg actttgacat
    59101 ggttcctctg atcgatgcct ttgtcaagaa acatcctgat ttttcttatc gaggcgcaaa
    59161 aggtaccttg gccctgacag gttacaacgg agttttaggt tatcgaacat caaaatctca
    59221 atatggagac aatgaaaaaa caaaaaaaga gattaaagaa gctaaaaaag tggcggaaca
    59281 gttgaagaaa gacggctgga gctttgcttc ccatacatgg ggtcacttga atatgactca
    59341 agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg cagcaagaag ttgcacctat
    59401 cctaggaaaa acaaatattc tgatttatcc atttggtgca gacatcagcg actggcagcc
    59461 ttattcagca gaaaatcaaa aatttgctta cttgaagagt caaggtttcg atattttctg
    59521 taatgtcgat gcttctacac cagcttgggg acaattaggt acggatttct atcgaaatgc
    59581 tcggatcaat atcgatggca ttcgttttca atctgattta gacggaaaaa atcctattct
    59641 tgatccattc atcaatgtcc atgatgtcta tgacaaagaa gcacgcgaat ctgcttgatt
    59701 ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt atcgtcagtt tcggcttttt
    59761 tatgctttat ttcttcttcg gtgcgattcc cttgatcagg acttctgtcc attctgctgt
    59821 atatggaagc agttttgcgt atatctccgg cttagaaatt ccttctacca ttgcttgaaa
    59881 atagaggatc aagaactcat ccgaatattt caaatccact tttccttctt tccgccctcg
    59941 atggaaaaga tcaagcatga tactgaaact ttcttgcgta tacgcatcca tcgcgtcaga
    60001 aaattctttt ttttcttttt ttgtatagta tgtcatcaaa tcgatataaa attgtttgtt
    60061 cactcgattg agataacgga ttttgttttc actcatggca atcagtgttt cttcaaatgg
    60121 aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa tcattcataa atgcaaaaaa
    60181 tacttcataa atcagccctt ccttgctgcc aaaatattta aaaatcgtcg ctttacttac
    60241 ctgagcgttc tcagctacct tatccattgt cactccagcg gttcctatgt ctgtgttcat
    60301 caagtcaaaa gctgcttgta aaatctcttt ctttttctct tgtgctctct tttcaaaacc
    60361 gttcatttgt agagcctccc gtaattttaa acttttataa tatatatagt tcaaatttat
    60421 tctgaggttt attataacta tctattgaga aagtatcaag ctagcaattc cttgtttatg
    60481 aattc
//
LOCUS       DAFTHM010000006        59403 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFTHM010000006 DAFTHM010000000
VERSION     DAFTHM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.006"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            161..391
                     /locus_tag="L7C88_000402"
     CDS             161..391
                     /locus_tag="L7C88_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBP9557262.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            488..1789
                     /gene="murA"
                     /locus_tag="L7C88_000403"
     CDS             488..1789
                     /gene="murA"
                     /locus_tag="L7C88_000403"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBP9557263.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1802..1978
                     /locus_tag="L7C88_000404"
     CDS             1802..1978
                     /locus_tag="L7C88_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBP9557264.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2113..2409
                     /gene="yidD"
                     /locus_tag="L7C88_000405"
     CDS             2113..2409
                     /gene="yidD"
                     /locus_tag="L7C88_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBP9557265.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2473..2940
                     /locus_tag="L7C88_000406"
     CDS             2473..2940
                     /locus_tag="L7C88_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9557266.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3025..3909
                     /locus_tag="L7C88_000407"
     CDS             3025..3909
                     /locus_tag="L7C88_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBP9557267.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4023..4259
                     /locus_tag="L7C88_000408"
     CDS             4023..4259
                     /locus_tag="L7C88_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBP9557268.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4347..4427
                     /locus_tag="L7C88_000409"
     tRNA            4347..4427
                     /locus_tag="L7C88_000409"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4381..4383,aa:Tyr,seq:gta)
     gene            4434..4505
                     /locus_tag="L7C88_000410"
     tRNA            4434..4505
                     /locus_tag="L7C88_000410"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4466..4468,aa:Gln,seq:ttg)
     gene            4630..4800
                     /locus_tag="L7C88_000411"
     CDS             4630..4800
                     /locus_tag="L7C88_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557269.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5020..5727
                     /locus_tag="L7C88_000412"
     CDS             5020..5727
                     /locus_tag="L7C88_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBP9557270.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5787..6431)
                     /locus_tag="L7C88_000413"
     CDS             complement(5787..6431)
                     /locus_tag="L7C88_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBP9557271.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6558..6845
                     /locus_tag="L7C88_000414"
     CDS             6558..6845
                     /locus_tag="L7C88_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557272.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            6953..7273
                     /locus_tag="L7C88_000415"
     CDS             6953..7273
                     /locus_tag="L7C88_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9557273.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7354..8667
                     /locus_tag="L7C88_000416"
     CDS             7354..8667
                     /locus_tag="L7C88_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBP9557274.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8664..9383
                     /locus_tag="L7C88_000417"
     CDS             8664..9383
                     /locus_tag="L7C88_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBP9557275.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9511..10062
                     /gene="raiA"
                     /locus_tag="L7C88_000418"
     CDS             9511..10062
                     /gene="raiA"
                     /locus_tag="L7C88_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBP9557276.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10284..12818
                     /gene="secA"
                     /locus_tag="L7C88_000419"
     CDS             10284..12818
                     /gene="secA"
                     /locus_tag="L7C88_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBP9557277.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPHHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            12944..14045
                     /gene="prfB"
                     /locus_tag="L7C88_000420"
     CDS             join(12944..13015,13017..14045)
                     /gene="prfB"
                     /locus_tag="L7C88_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBP9557278.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14150..14836
                     /gene="ftsE"
                     /locus_tag="L7C88_000421"
     CDS             14150..14836
                     /gene="ftsE"
                     /locus_tag="L7C88_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBP9557279.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14820..15713
                     /locus_tag="L7C88_000422"
     CDS             14820..15713
                     /locus_tag="L7C88_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557280.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15865..17313
                     /gene="cls"
                     /locus_tag="L7C88_000423"
     CDS             15865..17313
                     /gene="cls"
                     /locus_tag="L7C88_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBP9557281.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17650..18507
                     /locus_tag="L7C88_000424"
     CDS             17650..18507
                     /locus_tag="L7C88_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBP9557282.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18622..19542
                     /gene="pstC"
                     /locus_tag="L7C88_000425"
     CDS             18622..19542
                     /gene="pstC"
                     /locus_tag="L7C88_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBP9557283.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19542..20426
                     /gene="pstA"
                     /locus_tag="L7C88_000426"
     CDS             19542..20426
                     /gene="pstA"
                     /locus_tag="L7C88_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBP9557284.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20441..21247
                     /gene="pstB"
                     /locus_tag="L7C88_000427"
     CDS             20441..21247
                     /gene="pstB"
                     /locus_tag="L7C88_000427"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBP9557285.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21263..22021
                     /locus_tag="L7C88_000428"
     CDS             21263..22021
                     /locus_tag="L7C88_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBP9557286.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22034..22711
                     /gene="phoU"
                     /locus_tag="L7C88_000429"
     CDS             22034..22711
                     /gene="phoU"
                     /locus_tag="L7C88_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBP9557287.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            22949..23980
                     /locus_tag="L7C88_000430"
     CDS             22949..23980
                     /locus_tag="L7C88_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBP9557288.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            23977..24744
                     /locus_tag="L7C88_000431"
     CDS             23977..24744
                     /locus_tag="L7C88_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBP9557289.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24844..26412
                     /gene="liaX"
                     /locus_tag="L7C88_000432"
     CDS             24844..26412
                     /gene="liaX"
                     /locus_tag="L7C88_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBP9557290.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26709..27029
                     /locus_tag="L7C88_000433"
     CDS             26709..27029
                     /locus_tag="L7C88_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBP9557291.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            27029..27379
                     /locus_tag="L7C88_000434"
     CDS             27029..27379
                     /locus_tag="L7C88_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBP9557292.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27546..28484
                     /locus_tag="L7C88_000435"
     CDS             27546..28484
                     /locus_tag="L7C88_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBP9557293.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28499..29329
                     /locus_tag="L7C88_000436"
     CDS             28499..29329
                     /locus_tag="L7C88_000436"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBP9557294.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29373..30398
                     /locus_tag="L7C88_000437"
     CDS             29373..30398
                     /locus_tag="L7C88_000437"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBP9557295.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30413..31351
                     /gene="galU"
                     /locus_tag="L7C88_000438"
     CDS             30413..31351
                     /gene="galU"
                     /locus_tag="L7C88_000438"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBP9557296.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31476..31916
                     /locus_tag="L7C88_000439"
     CDS             31476..31916
                     /locus_tag="L7C88_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBP9557297.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            31919..32521
                     /locus_tag="L7C88_000440"
     CDS             31919..32521
                     /locus_tag="L7C88_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBP9557298.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(32580..33686)
                     /locus_tag="L7C88_000441"
     CDS             complement(32580..33686)
                     /locus_tag="L7C88_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBP9557299.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            33896..34897
                     /gene="ccpA"
                     /locus_tag="L7C88_000442"
     CDS             33896..34897
                     /gene="ccpA"
                     /locus_tag="L7C88_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBP9557300.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(35234..37579)
                     /locus_tag="L7C88_000443"
     CDS             complement(35234..37579)
                     /locus_tag="L7C88_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBP9557301.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            37858..38760
                     /locus_tag="L7C88_000444"
     CDS             37858..38760
                     /locus_tag="L7C88_000444"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBP9557302.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            38973..40748
                     /locus_tag="L7C88_000445"
     CDS             38973..40748
                     /locus_tag="L7C88_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBP9557303.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(40814..42400)
                     /locus_tag="L7C88_000446"
     CDS             complement(40814..42400)
                     /locus_tag="L7C88_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBP9557304.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            42651..42875
                     /locus_tag="L7C88_000447"
     CDS             42651..42875
                     /locus_tag="L7C88_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBP9557305.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            43017..44768
                     /locus_tag="L7C88_000448"
     CDS             43017..44768
                     /locus_tag="L7C88_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9557306.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            44768..46552
                     /locus_tag="L7C88_000449"
     CDS             44768..46552
                     /locus_tag="L7C88_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557307.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            46878..47729
                     /locus_tag="L7C88_000450"
     CDS             46878..47729
                     /locus_tag="L7C88_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBP9557308.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            47783..49534
                     /locus_tag="L7C88_000451"
     CDS             47783..49534
                     /locus_tag="L7C88_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBP9557309.1"
                     /translation="MAKPSTNKLEGIEMGKYQELARKIVENVGGKENINGLTHCITRL
                     RFKLKNEEKANDEILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAV
                     STEKMRPFDMLIDGISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNI
                     GDSVFQFMPVIIGLTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSG
                     TIFEAPIYQTVFGIPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFF
                     TVLITMPLGFLLVGPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWA
                     IVPMGLMQFSVNGWQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVG
                     ITEPAIYGFTLPRKKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGD
                     LTDVINVLIGIAIAMVVSFTLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNA
                     AKDAAFAQGTLGRGILIYPEKGEVRAPFDGTVMTLFPTKQAIGMVSETGLELLIHVGL
                     DTVQLEGKYFESLVQQG"
     gene            49538..49708
                     /locus_tag="L7C88_000452"
     CDS             49538..49708
                     /locus_tag="L7C88_000452"
                     /inference="COORDINATES: protein motif:HMM:NF012578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBP9557310.1"
                     /translation="MKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGET
                     VGPDDALITALT"
     gene            complement(49748..50650)
                     /locus_tag="L7C88_000453"
     CDS             complement(49748..50650)
                     /locus_tag="L7C88_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBP9557311.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            50881..52284
                     /locus_tag="L7C88_000454"
     CDS             50881..52284
                     /locus_tag="L7C88_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBP9557312.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            52284..53717
                     /locus_tag="L7C88_000455"
     CDS             52284..53717
                     /locus_tag="L7C88_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBP9557313.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            53862..54788
                     /gene="trxB"
                     /locus_tag="L7C88_000456"
     CDS             53862..54788
                     /gene="trxB"
                     /locus_tag="L7C88_000456"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBP9557314.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            55002..56729
                     /locus_tag="L7C88_000457"
     CDS             55002..56729
                     /locus_tag="L7C88_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBP9557315.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            56744..57094
                     /locus_tag="L7C88_000458"
     CDS             56744..57094
                     /locus_tag="L7C88_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBP9557316.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(57186..58046)
                     /locus_tag="L7C88_000459"
     CDS             complement(57186..58046)
                     /locus_tag="L7C88_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBP9557317.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            58138..58566
                     /locus_tag="L7C88_000460"
     CDS             58138..58566
                     /locus_tag="L7C88_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBP9557318.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            58728..58904
                     /locus_tag="L7C88_000461"
     CDS             58728..58904
                     /locus_tag="L7C88_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBP9557319.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            58931..59377
                     /locus_tag="L7C88_000462"
     CDS             58931..59377
                     /locus_tag="L7C88_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBP9557320.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT        19343 a        10318 c        12731 g        17011 t
ORIGIN      
        1 tttgtctcag tccctttttt tgcatatttt tagcatttat ttcctaaaaa atgtaagggg
       61 attcctatat ttttaagtat acttgttttt ccttttatac attttatggt attatcattt
      121 tattagttat tataaaacaa tcgttagaaa ggacgtcatt atgcaagtat acggaattga
      181 tgcggtgctt cgaatcgtga gtcatttggc gtttatctac ttagccttct ggtctttacg
      241 ttcgttacgc attgaaactt ttttcagacc aatgcataat acgcaaatta gaatggcaat
      301 cgtacttttt tcaatttttt tagggtacac tgcaagtaat tttttcttag aagttatcgc
      361 tttatgccga aatcttttcg ttagcctgta aattttaaaa aaaggtacta ttttaaaagc
      421 aaggatgtta taatagaaaa gattttgagt aagtgtatgc tcattggaat tttttggagg
      481 gaacaacatg gaagagatca tcgtaagagg tggcaatcaa ttaaatggaa cagtaagaat
      541 tgaaggagct aaaaatgctg ttttgcctat tttagctgct agtttgttag cagaagaagg
      601 tattacgaca ttagacaacg ttccgattct ttctgatgtc ttcactatga atcaagtgat
      661 tcgtcactta aacgtagatg tagattttga tgaacaaaag aatcaagtaa caatcgatgc
      721 ttcaagacaa ttagaaatcg aagcgcctta tgagtatgtt agtcaaatgc gtgcttcaat
      781 cgttgtgatg ggtccgctac ttgccagaaa tggacatgca aaagtagcta tgcctggtgg
      841 atgtgcgatt ggtaaacgac caatcgattt gcatttaaaa ggatttcaag ctttaggagc
      901 aaaaattatt caaaaaaacg gctatatcga agcaattgcg gatgaattga tcggtaacac
      961 gatttattta gatttcccta gtgtaggtgc tactcaaaat atcatgatgg ctgccgtaaa
     1021 agcaaaagga acaaccatca ttgaaaacgt agctcgcgaa ccagaaatcg ttgatttagc
     1081 aaacattttg aataaaatgg gcgctcaagt ctatggagct ggtactgaaa caatgcgtat
     1141 tgaaggcgtg gatcatttac atgcagtcaa ccactcaatc gtacaagatc gtatcgaagc
     1201 aggtaccttt atggttgctg ctgcaatgac acaaggcaat gtgctgattg cagatgctat
     1261 ctctgaacat aaccgcccat tgatttctaa attgatcgaa atgggtgcag aaatcattga
     1321 agaagaaggc ggagtccgtg tcatcggacc aaaacatatc ttacctacag atgtaaaaac
     1381 gatgcctcat cctggtttcc ctacagatat gcaagctcaa atgacagcta tccaattagt
     1441 tgcagaaggt acaagtgtag tgactgaaac agtgtttgaa aatcgtttcc aacatttaga
     1501 agagatgcgc cgtatgaacg ctcatgtcaa aatcgacgga aatgtagcaa tcatggatgg
     1561 aaaccatgaa ttgcaaggtg cagaagtata tgcaacagac ttgcgggcag cagcagcatt
     1621 agttttagct ggcttgaaag caaatggaat cacacgtgtg cgtaacttga attatctaga
     1681 ccgtggatat tataatttcc atatcaaact acagcaatta ggtgcagacg ttgaacgtgt
     1741 agacatggat caaacttctg ctgaaaaaac agcacaaacg attgcttaag gaagtggctg
     1801 aatgagtaac caacgatata tcttattaac tttgataaag attttagtgg tgatcttatt
     1861 gcttatcctt ctttttgtgg ccggaacgat gatcggatat ggtgtcatcg gtggcggcaa
     1921 tccatttaaa gtattccagc caagtttgtg gattcatatt cgagactttt ttcattgata
     1981 aataagaatc acagtggttc tagtcgatat gaagtgagcc atgaagcaga acatgacaaa
     2041 agaaaacaga agggaacgtt gacgttagtc gcgatccctt tttttagtaa aagaaaagaa
     2101 ggaatctaat tgatgaagaa gatattgatt tatttagtta gaggatatca gcgctttatt
     2161 tcgcctgcat ttccacctag ctgccgttat tacccaacct gttccaatta tatgataaaa
     2221 gcaattcaaa cccatggtgc actaaaaggg acggtaatgg ggactgcacg gatcttacgc
     2281 tgtcatcctt ttgtcaaagg cggtatcgat tatgtaccat tgacattcca attaacgcga
     2341 aataagaaag ataaaaaaga accagattat aaaaaggttg tgaaaaatac gagtagcact
     2401 gagcgataaa gaaaaagagg aaaattattg tcaaagtaac aactccgcaa ctacttatat
     2461 gggggacaaa aaatgatcga agaactaaac aagaaagatt taccatggtc cttgttatta
     2521 gatgcagatc ctgataaaga aaaagttcaa gtatatgttt ccagagggag tggctggata
     2581 tggaaagaaa aagaaaaaac aataggtgta ctgatctatg tggcaaggga aaaagaatac
     2641 gaaatcgtca atgtagcagt agccccaacg tatcaaggaa aggggattgg cggaaaatta
     2701 cttgagacag cttttcagaa gctttcacaa ctcgcttcca gtcaaactca gatcatcata
     2761 cgaaccggca gtactagcag tgcggcgtta catctctatc aaaaaatggg ctatgtggag
     2821 attggtcgag tcaaagacta ttttatccat cattactctg agcccatttt tgaaaatgga
     2881 gatcaattaa gggatcaagt aattttagca attcacttac ctaaaaatag ctttaactaa
     2941 taaactttca attcgagaaa atgctttcaa atgctaaata gatacattac aatagcttta
     3001 gcaaacaaaa aggagaatat ttttatggga atattagttt ttgattttgg tggatcggct
     3061 gtcaaatatg gttgttggga tggcaaagag attaaaggta agggacaatt tgcaacgcct
     3121 gaatcttggg aagaaatgaa agcgcaatta tttcaagttt ataaaaaaat actcgtttct
     3181 tttgaagtcg aaggaattgg aatcagctct cctggagtag tgaataatga gaaacaggtg
     3241 attgagggaa tcagtgcgat tccttatatt catggattta atattttccg agatttggaa
     3301 actctgtttc aactcccagt aacgattgaa aatgacgcca actgtgccgg aatggctgaa
     3361 ttttatgaag gtgctgcccg tgattatcaa gatgttgctt ttgttgtggc aggaactggg
     3421 attggcgggg cgttgttcac gaaaggacaa atcaataaag gggcacatct ttatggtgga
     3481 gaatttgggt tgatgttctt aaatggcgat aagacattca gtaaacttgg tacagcggta
     3541 cagatggctt ggcgttattg tgaacgcaaa ggtctcgata aaaattctta taccggaaaa
     3601 gatgtctttg aattagcaga aactggagat gcaatagcaa aagaagaagt tgagagtttt
     3661 tatacgtatc ttacaaaggg attattcagt attcaatttt cgtttgatcc agaagtgatc
     3721 gtattaggcg gcggtgtttc tgcaaaagaa gggctcattg atgagatcaa aagccgaatg
     3781 aagaagctga cagaacaatt cgatctgcat gatttcgaac cgcagatttt attatgtgaa
     3841 tacagaaacg atgctaatct tgtaggtgca gcagcaaact atctcgctgt acgtcaaggg
     3901 gagaattaag agctttagag aaggtgcagc ttgcataaaa gaagtgaatg aaatgaatag
     3961 gagattttta cctaaggaat gttttatttg ctgcagtatg ataaaatatc tgagaggtga
     4021 aaatgatgtc aaaaaaaaat aaagatgttg aagtgcgtat agaagaagtg aaaaaagata
     4081 tcaaaggtaa gaattatgaa gtcactcagt tatttatagg gaaaaaaatg attggtgaga
     4141 tcttagccta tgggccaaaa gaatatgaaa ttttctttgg tgaagaagat tttggaaaag
     4201 aaaaaagtct tgaaaatgcg atagaaacag tgattcgaca ctggaatctg cacgaataaa
     4261 aaaatatcaa aaaaactttc aataaagggt tgcaaaaatc tggaaaatta ggtattataa
     4321 ctaagtcagg ttgatacaaa cctttcggag gagtagcgaa gtggctaaac gcgacggact
     4381 gtaaatccgt tccttagggt tcagtggttc gaatccactc tcctccattt cattggggta
     4441 tagccaagcg gtaaggcaag ggactttgac tccctcatgc gttggttcga atccagctac
     4501 cccagtatac cacaatcgta agctctcgtt agttcgagag ctcttttttt tgctttgcta
     4561 ccttgttcct tgaagattct gctgatttaa gatagagtta agttaactac aagaattgga
     4621 gggatccaca tgaaatggaa agaaaaagta gacgaagcag ctgaaaagtt atatgatttg
     4681 gtcaaatcag aaaaatacaa tattgaagtg aatattccga aaaaaggcgg aaaagcggtc
     4741 caggtaaaat caaaacgccc aacgaatcat acaaaaaaat ggatggctaa aaaccgctaa
     4801 taataacaaa agatccataa gtcggcattt tcatcgattt tagggtcttt tgttattttc
     4861 taggttgaac atatctaaaa aattgtttct gacaatagga gtaggaagaa cgatgtgtgt
     4921 ctaaatcctc tgttgatgga tagaaacctt tatctttttc agttgtgaat caggtatata
     4981 ccagttataa tagaagaaac gaaaggacgg gtgtacgtta tgtcgaatca attacctgta
     5041 tatatacaga ttcatgacca attaaaaaat gaaatcgaac aaggtatatg gaaagtcgga
     5101 gaccgtcttc cttcagaaag agaattagca gtgaaattca atgtcagccg tatgacgttg
     5161 agacaagcaa ttcaaaactt ggcagatgaa ggaatcttag aaagaaagat cggttcgggt
     5221 acatatgttg cgcgagaaaa agtacaagaa aaaatgtctg gtgcaacaag ttttacagaa
     5281 attatggaat cgcaaaatcg agtaccgtct agtcggacaa tctcttattt cttgacttcg
     5341 ccaagctcaa gtgaaatgga aaaactaaac ttgagtaaag atgacacgat cttgcgaatg
     5401 gaacgtattc gtttcgcaga tgatgtccct atttgttttg aagttgccag tgtgccacaa
     5461 aagctgatcg atggctacag caaagcagag attactgaat cgttgtatcg cacgctagaa
     5521 gaaaaaggcg ggaaaaagat cggtccagcg aatcaaacga ttactgctgt gttggcttct
     5581 gagaaaattg ctgactattt agaggtaaaa cgaggagatg cagttcttcg tttgcgccag
     5641 atttcttatt ttgaagacgg tacgccgttt gagtatgtgc gtacgcaata cgtaggaaat
     5701 cgttttgagt tttatttgga aaaataaaaa acaggtgatc cctgattcct tacttagaaa
     5761 taaaagagaa tcagaatcac ctgtttttat atatgatcag ttaccagttg ctcgtgataa
     5821 gaaacaggac cctcttcaaa ttggacttgt ccgttcagca gctcaatgat ggattcttta
     5881 aagtggtcag cacttttttc atctacagca cagatgacgc taacttgatc agtatattgg
     5941 atttctttta taaaaaaatg ttggagttca agataattct gtaattttcc tagttgcgga
     6001 tacgtgatca tcacagagat ctcctgttgc aaggtacctt ctacgattcc aatgtcagac
     6061 aatgcttgag agacagcatg agtgtatgct cgtattaatc cgcctgtgcc gagtttcgtt
     6121 cctccaaaat atcgagtgac tactgcagct acattgatca gttgattttt tttgaggact
     6181 tccaacatcg gtacgccagc cgttccactt ggttctccat catcgctgct tcgctggatt
     6241 tcattttttt ctccaatgat gaaggcgctg cagttatggt tcgctttcca atgttctttt
     6301 tttatttctt gaatgaaact ttttgcttgg tcctctgatt ctattcgtct aagagaacag
     6361 ataaagcgtg attttttgat ctcaatctca ctttgtccat tttcttttat tgtacgatag
     6421 cgctcgatca tcttgtcacc tctttttttc attttcttta ttcagtataa ataaagttct
     6481 aggttgtttc aacactgtaa cggttgcgca atcgctgtag tatgcgataa taaagacaaa
     6541 ggtaggtgga tctggggatg caggaacgaa tgaaaaagta cgatgcaatt acgcattatt
     6601 tgaagaacaa tggcggctct caagtaacgt tgacctttac ccaatttgac gaactgctgt
     6661 ttcccagtaa cggacttccc aaaacagcaa gggaaagtac agattggtgg gcaaatgatt
     6721 ataaacaccc tgaaaaaggt gcctatggct ggataaatgc aggctatgaa gtagttgtca
     6781 tcaatttgga caaagaatat gtcgtgttca ataaattagt gaaatctagt tggctatttg
     6841 attaaataaa ccgcgtttag aaaacgttga caaatttctt tctttttata taatagagta
     6901 acagacgcga agaaaacgtt tgcgtagttt gttttaaaaa ggagagaaaa gtatggctaa
     6961 aaaaacaatc atgcttgtat gttcggctgg tatgagcaca agtttactag taacaaaaat
     7021 gcaaaaagct gctgaagcaa aaggaatcga ctcggatatt ttcgctgtgt ccgcttctga
     7081 cgcagataac aatcttgcaa ataaagatgt agatgtactg ttattaggac ctcaagttcg
     7141 ctttatgaaa gctgattttg aaaaacgtct ggaaccaaaa ggcattcctt tagacgtcat
     7201 caatatggct gattatggta tgatgaatgg cgaaaaagtg ttagatcaag caatcacgct
     7261 cataggtgaa taaatagaac agtataacta tcgaacaagc gatccaaaaa atagatcgct
     7321 tgttttttcg tatatttttt tagggcgaat aatatgaatc atttttgggg tagaaggctt
     7381 ctgacgagag atattaaagc aatagactgt gaggaggtaa atttaccaaa ttatgagaag
     7441 atcgcagcag tggaacgttt gggcaactgg attctttgtc atcgctgtgg aatgaggacg
     7501 tccgtcattg atggacagct tgcagattac ggttattttt gtacacattg tctatattta
     7561 gggcgatgcg acactcaaca agatttatat ttgtttgatc agcctgaagc aaaacctcga
     7621 gaagtcgtct ttttttggac aggacagctt actgaaaaac aaacggaaat cgcaaagaga
     7681 atactttgcc attcagaaaa aagacatcat cttatttggg ctgtaacagg tgcagggaaa
     7741 acagagatgc tttatcctat tttagtggaa actttaaaag ctggaggaag agtagcgatt
     7801 tgtacaccgc gagtcgatgt ttgtaatgaa ttgtttttac gctatcgtta tgtttttcca
     7861 gaagaaaaaa tcacgttgct ccatgggaat acagcaacgg cttatacctt tacttctttt
     7921 gttatctgta cgattcatca gctataccgt ttttatcggt cctttgattt aatagtgatc
     7981 gatgagatcg atgcgtttcc ttataacggg gatgcaggat tagctcatgc tgtgcaaaca
     8041 gcgattaaac cagacggacg attcatctac ttaagtgcca cacctgataa aaagttacta
     8101 aaggaaatca agcagacgtt tgacatccac aaacttgctt tgcgctttca tcggcgttta
     8161 cttcctgaac ccgtcttggt tttcatgaat aattggcgac aaaaatgcaa gaacaagaag
     8221 aagataaaat ctttggtgcg gatcattcat caattaatta aagaaaacca tatcctttta
     8281 ttttgtccaa gtatcacgat gatgcatcgt ttgaaagcca cacttcaaga ggctcttccg
     8341 agatatgaga tcacagatgt ttcttcaaga gacaatcagc gggcggaaaa agtccagaaa
     8401 atgcgagaag caaaatatga catactgtta accacgatga tccttgaacg tggagtcaca
     8461 tttgaaagaa tatccgttat cgttttagga gcggatcatc cggtttttac taaatcttct
     8521 ttggtacaaa tcgcaggaag agccgatcgt aaagggcctt atacgaacag tcaagtatac
     8581 tttttctatg aagaaaaaac tgcagctatt cgaaaagctt gtcaggaaat caaagaaatg
     8641 aatgaagaag ggaagaagat gctgtgaggt gcagttgctg cagtaaagat atcgtccaaa
     8701 atttaacatt cagcgagatt attggtgttt cgaaatacag attacctcag acttgttcag
     8761 tttgtcgcgc acaatttcat ttattggaaa caagaggctg ttctggctgt caaaaaccaa
     8821 tccatttcaa tctagagagt acgaaaaaga aagtaaagtc tattcccgtt tactgcagtg
     8881 actgtcaaga atggaagaag aaatatccga cctatgattt tcagcaccgt gccttttttg
     8941 tgtacgatga aaatatgaag gcctggctca atcaatacaa gtttatggga gatatccgac
     9001 tagcaggcac ctttgcatat aaatggacgc agataaaaaa agaatacccg acatacatct
     9061 attgtccaat acctttatct gaaaaaaggc gaacagaaag aggattcaat caagtaagcg
     9121 agatgttgaa agcagcaaga attccttttc agatgctact caaaagagag aagcatctgc
     9181 tggctcaagc aaaaaacacg cgaaaggaaa gattggagat gcctcaacct tttgaacttg
     9241 cagtcacctt ttctaagata caaaataaaa aaatattgat tattgatgat gtctatacaa
     9301 caggacagac tcttttccac gcagcagatt gtttgcaggt cgcacagccg aaaatcatcc
     9361 gaaccatttc tttagcaaga tgaattagat gtggaaattt gatagcgatt taatttgcaa
     9421 ataacctaga gttcgatata atagaattaa gaagagggaa agagtggtcc ttctccttct
     9481 tgattgtggt agacgaaagg ggtaattttt atgtttagat ataatgtacg cggcgaaaat
     9541 atcgaagtaa ctgaagcgat tcgcgactac gttgagaaaa aagtaggcaa actagaacgc
     9601 tatttcagtg acgcacccga tgcaacggcg catgtgaact taaaagttta tacagaaaaa
     9661 acagcaaaag tggaagtaac gatcccatta ccttatcttg tattacgtgc cgaagaaact
     9721 tctccagatt tatacgcaag tatcgatttg gttgttgaca aattggaacg ccaaatccgc
     9781 aaattcaaaa caaaaattaa tcgtaaatcc cgtgaaacgg gcatgaatac tgcagatgct
     9841 actgctttat tcaatgaaga ggacgaaaac gaaaatgatt ctgaattaga tatcgtacgt
     9901 acgaaacgcc tttcattgaa accaatggat agtgaagaag cagtcttaca aatgaacatg
     9961 ctgggacata acttctttat ttttgaagat gcagaaacaa atggtacaag tatcgtttac
    10021 cgccgtaaag atggaaaata cggactgatt gaaacagact gatcagcctt acttaaataa
    10081 caacgaaaac ttgcagcagc tactgacagc tgccgcaagt ttttttgagt ttcctcctct
    10141 tttagatgaa atatgaataa attatgaagt tcttacttta atacgcttaa gatatttcaa
    10201 ttatctataa ctaatgataa aatgaaaagt aaagtctaca tagtctggat aatacacaga
    10261 aggaaaagga gattacacaa cgcatggcca atttgattcg ttcacttatc gaaaacgata
    10321 agaaagaact aaaacgttta gatagcattg caaaaaaagt tgaagcatac gctgaccaaa
    10381 tggcagcatt aactgatgaa caattacagg caaaaactgc tgaattcaag ggcagatacc
    10441 aaaaaggaga aacattagat caattacttc cggaagcttt tgcagtcgtc cgagaagcag
    10501 caaaacgtgt attggggtta tatccacacc acgtacaatt gatgggtgga atcgtgcttc
    10561 acgatggaaa tatccctgaa atgcgtactg gtgaaggtaa aaccttgacc gcaacgatgc
    10621 cagtatatct aaatgctctg actggcgaag gggtacacgt agttaccgtc aatgaatatt
    10681 tagcaacccg tgactcgacg gaaatgggcg aactttataa tttcttagga ttaacagtgg
    10741 ggttgaatat caactcaaaa tcttcggatg aaaaacgcga ggcttataat tgtgatatca
    10801 cttatagtac gaataatgaa ttaggatttg actacttgag agacaatatg gtcgtttacc
    10861 gccatcaaat ggtacaacgt ccgctgaatt atgccattgt cgatgaagtt gactcaatct
    10921 tgattgatga agcgagaacg ccgctgatca tttcagggca agcagaaaaa tccacagctt
    10981 tatatacaag agcagacaac ttcgtgaaac gtttgaaaga agaagaagat tataaaatcg
    11041 atgtacaatc aaaaacaatc agtttaaccg aagcagggat cgaaaaagca gaagaaacat
    11101 tcggtttgga taacttatac gacattgaaa atactgcatt gacccatcac ttggatcaag
    11161 cattgagagc caactatatc atgcttttag atatcgatta tgttgtccaa gacggaaaag
    11221 tactgattgt tgaccagttc actggtcgga tcatggatgg acgccgttat tcagatggac
    11281 ttcaccaagc aatcgaagct aaagaaggcg tagagatcga agacgaaacg aaaaccatgg
    11341 cgacgatcac tttccagaac tatttccgta tgtacaagaa acttgcggga atgactggta
    11401 cagctaaaac agaagaagaa gaattcagag aaatttataa catccaagta taccagattc
    11461 cgacaaatcg tccggttatc cgtgatgatc gtccagattt gctttaccca acattacaaa
    11521 gcaagttcca cgctgtcgtg caagatatca aagatcgcta ccgcaaaggt caacctgtgt
    11581 tagtcggaac tgttgcggtt gaaacatctg agttattatc agatatgctg aatcaagaac
    11641 gtattcctca tgaagtgctg aatgcgaaaa atcactttaa agaagcagag atcatcatga
    11701 atgctggtca aaaaggtgct gtgacgattg ctaccaacat ggctggtcgg ggaacagata
    11761 tcaagttagg acttggggta agagaacttg gtggtctagc agttatcggg acagaacgac
    11821 atgaatctcg tcgtatcgat aaccagcttc gaggacgtgc aggacgtcaa ggagaccctg
    11881 gtatgtcaca gttctacttg tcattggaag atgatttgat gaaacgattc ggttcagaac
    11941 gaatcaaatc tttcttagat cggatgaaga tcggtgagga agatgctgtt atccaaagca
    12001 agatgctgac gaaacaagta gaatctgcac aaaaacgtgt agaaggaaat aactatgaca
    12061 cacgtaaaaa cgtcttacaa tacgatgatg tgatgcgtga acaacgtgaa gtaatctata
    12121 aacagcgaca agaagtaatc atggaagaaa aaagcttatc caagccacta atgaacatgg
    12181 tcaaacggac aatcagtcgt gtagtagatg cgcatacaca attagagaaa gaaaattgga
    12241 atttggaaag tatcatcgat tttgccggca gtactcttgt ccatgaagat agtattactc
    12301 ttgcagatat cgaaggaaaa acagctcagg agatcaaaga gtatctaaac gaacgagcac
    12361 aagaagtatt taataccaaa gcggctcaac taaatggtcc agagcaactg ttggaatttg
    12421 aaaaagtcgt gatcttgcgt gttgtggact ctaaatggac agaccatatt gatgcaatgg
    12481 atcaattacg tcagtcaatc ggcttacgtg cttatggaca gaacaatcca ttagtcgaat
    12541 atcaaacaga aggctataag atgtttgaag atatggtagg cgccatcgag tatgaagtca
    12601 ctcgaatctt tatgaaagct gagatccgtc aaaacgtaca gcgtgaacag gtttctcaag
    12661 gaacagcttc tcactcagaa gacggagatg ccaaagaaaa tagtaatact agcgcgaaaa
    12721 aacagccaat ccatgtgaac aaggtcggaa gaaatgatcc ttgtccttgt ggaagcggga
    12781 aaaaatataa gaactgtcat ggaaaaaatg caaactaatt tctgacagca ggattggtga
    12841 gacaaattct ttttttaaga attcgtctca ccttctttct gttatttgct gattctgtta
    12901 gactagatat aatgaaaaaa gtatagtgaa agaaggaaaa aacatggaaa tatccgaaat
    12961 tcgaaatctc ctgacagaaa tgcaggaaaa ggtcacaagc ttcaggaggt ctctttgact
    13021 tagaccagct ggaagaagac attgcggaag cagaagcaaa aatggctgaa cctggttttt
    13081 gggatgatag cgaagctgct caaaaagtga tcagtgaaaa caatgcaaat aaagaaactt
    13141 atgatcaatt ccattctctt gctgaagaac tggaagaaat cgaattgatg gtggagatgt
    13201 tgcaggaaga acctgatgca gccatgcaag aagaagcaga aacacgtatc aatgcgctag
    13261 atgaaaaaat gaagacatat gaattatcta tgttgttaga tggtccttat gatcgaaaca
    13321 acgccatcgt tgaattgcat ccaggggctg gcggaacgga gtcccaagat tggggcagta
    13381 tgcttttacg tatgtataca cgctgggcag agcagcatgg gtatcaagta gagacactag
    13441 attatcaagc aggtgatgaa gcaggaatca agagtgtgac cctactgatc aaaggacaca
    13501 acgcatttgg ttatctgaaa tcagaaaaag gtgttcatcg ccttgtacgt atctcgcctt
    13561 ttgactcagc gaaacgacgt catacttctt tttgttcggt agatgtgatg ccagagcttg
    13621 atgaaacgat cgatatagaa atcaatccag atgatttgaa aatcgatacg taccgagcaa
    13681 gtggtgcagg tggtcagcac atcaataaaa cagaatctgc tgtacggatc actcacttgc
    13741 ctacaggaac agtagtagct agtcaggcac aacgttcaca attgaaaaac cgtgagcaag
    13801 cgatggggat gttaaaagct aagctttatc aattagaagt ggaaaagaaa gaacaagaag
    13861 cagctgcact tcgaggagaa caaaaagaaa tcggctgggg ttcacagatc cgttcttatg
    13921 ttttccatcc atattctatg gtaaaagacc atcggacaaa cgtagagaca ggaaatgtcc
    13981 aagcagttat ggacggtgac cttgatttat ttattgacgg ctatttaaaa atgcatctac
    14041 aataagaacc cattgttaaa ttgaaataaa attgtaagat tttgcaagca tgttgaaaca
    14101 ttgccatgct ataatagcta aagactgaaa aagatatgga gagaacgcca tgattgaaat
    14161 gaaggatgta atgaagaagt actcaaatgg tacgaccgct atccgcaatc tctcaattgt
    14221 catcgaacaa ggagagtttg tctatgtggt tggtccgtct ggagccggta aatctacatt
    14281 catcaaattg atgtatcgag aagaaaaagc ttcaaaagga actttgaacg tcgcaggtca
    14341 tgatctaata gcaatcaaaa accgcgaagt tccttatcta cgcagagaaa tcggcgtggt
    14401 gttccaagac tataaattat taccaagaaa aacagtatat gaaaatgttg cgtacgctat
    14461 gcaagttatc ggcagaaaac ctcgggatat caaaaaacga gtaatggaag tgctggacct
    14521 tgttggtttg aaacacaaag ttcgagtctt tcctagcgaa ttatccggtg gggaacagca
    14581 acgtgtctct attgctcggg caatagtgaa tacgcctaaa gtacttatcg cggatgaacc
    14641 gacaggaaat ctggatccag aaaactcatg ggaaatcatg aaattattag atcggatcaa
    14701 tgcccaagga actactgtcg tgatggctac acataacagt acgatcgtaa atacgattcg
    14761 gcaccgagta attgctatcg aaaacggccg cattattcga gatcaagcgg aaggggaata
    14821 tggatacgat gattagaacc tttttccgcc atttattaga aagtatcaag agtttgaaac
    14881 gtaacggctg gatgacagtt gcttcagtca gtgcggtaac gatcacattg actttagtcg
    14941 gtgtattcat ggcagttatc atgaacgcaa ctaaattagc tcaagatata gaaggaaacg
    15001 ttgatgtctc tgtattcgta gatatcggta caaaagacga agagatgaaa aagctagaaa
    15061 aagaattgaa tgacttagat catgttaaaa aagttgaatt ttcaagcaaa gaacaggaat
    15121 tgaaaaaaat ccaaaacgaa atgggtgatt cctggaaatt gtttgaaggt gacaataacc
    15181 cgttatatga tgtgtatgta gtaagtgcta ctgatccttc ttatacaaaa caagtagcag
    15241 aagaagcagc agatttgaag aatgtttctc gttctgatta cggtggagct tcctcagatc
    15301 ggattttcca aatcgctggt gcagttcgga catggggatt agttgcagcg gcattgctgc
    15361 tgttcgtagc gatgtttctc atttcgaaca cgattcggat cacgattttg tctagacagc
    15421 gtgaaattca aatcatgcgt ttagtcggtg caaaaaatgg atatattcgc tggccgtttt
    15481 tccttgaagg tggctggatc ggtctgatcg gtgcgattct tccgattttg atcatcacat
    15541 ttggttatgc atggtttttc caattgatca atccatcatt attacgttcc cattattcat
    15601 tgattcatcc acaaaatatc gtttggaaaa tcaatctttt aatggtcggc attggtgtga
    15661 tcattggttc acttggctcg atcatttcta tgagacgttt cttgaaattc taataccaca
    15721 atataaataa aatgagaaag ttggacagtt tcgttccagc tttctttttt tattggctag
    15781 gagaatagaa ggaagcggct tttttccctt tactttaaaa aacaacttgg gtattcttaa
    15841 gttggtagaa gaagaggtga agccgtgaaa attatcgttg acaatttttt tacgatcctt
    15901 ttgattatga atattttgct ttcctttatc atcgtttttc gagaaagaaa ggaaactgct
    15961 caaacatggg catgggtgct cgttttgatg ttcattccag ttgtaggatt tattttatat
    16021 atttttttag gaagagggat ttccaaagag aaaatctttg atttgaagat ccaagggaaa
    16081 atcggtaaga acctggaaat tgaagaagac aaacaggcat tgatgcgagg gctttatcct
    16141 catccgccta ctggacaagt agatgtgaaa caattgatct atatgctcac ggtatttgaa
    16201 agtacgctct atacgactaa aaatgaaatc actttattta cagatggtcg tgaaaaattc
    16261 gatgcgctga ttgaagatat caagcaggca gaagaccata tccacttcca gtattatatt
    16321 tatcgcagtg atgcattagg tgaagaagtt cgagatgcat tgacagaggc ggcaagacga
    16381 ggggtaaaag tcagagtcct tcttgatgca tggggttcca cacaagtttc ttccagcttt
    16441 tttcagaatt tgaaaaaagc aggcggagaa gtcgcatttt tctttcctct atttgttccg
    16501 tatattaatc ctcggatcaa ttatcgcaat catcgtaaaa tcgtagttat tgatgggaaa
    16561 atcggatata caggtgggtt caatgttgga aatgaatatc taggattggt aaagaaattt
    16621 ggttattggc gagacaatca tttgcgtatt tacggagaag cggtgtatac cttgcaaaac
    16681 cgttttttga tggactggaa ttctcagcat acaaaagaag taggctattc tcccaaattt
    16741 tttccgtcca ttcactctac tggtgatata gctgttcaaa tcgtgacaag cggaccagat
    16801 accgaacatg aacaaatcaa aatgacttat ttgaaaatga tttcgttagc caaacgggag
    16861 atattgatcc aaacgcctta ttacataccg gatggatcga ttcatgaagc actgaagttg
    16921 gctcttcttt caggcgtaaa agttcatatc caaataccta acaaaccaga tcatcttctc
    16981 gtttactggg caacgtattc tttcgctgca gagctaatcg agtatggagc aaggatcgaa
    17041 acatatgaga atggatttat tcatgcaaag acgatgatta tcgatggtgg cattgtttca
    17101 gttggctcag caaatatcga tgttcgttca tttcgcttgg actttgaggt caatacactg
    17161 gtttatgatg aacgaatggc ttcacgtgta agaaaagctt tttttgaaga ctcgaaaatt
    17221 tctacgcatc tcacaaaaga aatgtatgaa aaccgaggaa taatcatcaa gatgaaagaa
    17281 ggattagcaa gattgatttc gccgctcctt taaaacataa aaaggacatg agaaccatca
    17341 acagatggag atctcgtgtc cttttctaac ggggccattt ctgagagtac gtcagaaatg
    17401 gagaaagcgt ctcgcatgag cgaaattaac tttggggtat ctcttgtttt ttggggaaag
    17461 caagaaataa gctaatatat gctattaaaa gagacacatt tcaaagccag tatagcatag
    17521 aaacttttaa tgagatagtt ttttttacaa ttatgagaat ttattttgtt atttaatgat
    17581 tttgattcgt tttcatcaag taatgaaaat gataaaataa acatacttta ggattaaagg
    17641 agatttctaa tgaaaaaact taaattattc ttaccaataa taggattagc tattctttta
    17701 tcaggctgtt caaagtggat tgatcgagga gaatccatta cggctgttgg ctcttctgct
    17761 ttacagcctt tagtagaaac agttgctgaa acttaccaga cagaaaatcc tggaaaattc
    17821 atcaatgtac aagggggcgg aagcggaact ggtttgtctc aagtacagtc aggagcagtc
    17881 gacatcggaa actctgattt gtttgcggaa gaaaaatcgg ggatcgatgc ctcagcatta
    17941 gtcgatcatc gagtagcagt tgttgggatc actcctattg tgaacaagga tattggcgta
    18001 aaagacatca gtatggaaaa cctgaaaaaa ctatttacag gcgagatcaa aaactggagt
    18061 gaagtcggtg gaaaagatca gccagtagtt atattgaacc gcgcttcagg aagcggaacc
    18121 cgtagcacgt ttgaaaaatg ggtattggac ggagaaacag ctgttcaggc acaagaacaa
    18181 gattcaagcg gaatggtgcg ccagatcgtt gccgacacac ccggtgcaat cagctatgtt
    18241 gctttttctt atgtttccga tgatgtagat acgttgaatg ttaacggtgt agaaccgaca
    18301 gatgaaaatg tgacaacgaa caaatggacg atttgggcat atgagcatat gtacacaaga
    18361 gatcatccaa aaaaactgac aaaagaattt ttagactata tcttatctga tgaagtacaa
    18421 gataacatcg ttggagaact aggttatatc cctgtttctc atatgaaagt cgaacgtgat
    18481 tggcaaggaa atatcgttaa agagtaatct ttacacaaaa tttacaaact tagctaaact
    18541 tttacatgtt attaaaacca aattgatgtt caatttgtac actgagtgag tatgttaaac
    18601 ctgattaagg gggagtcatc tgtggaagat gtgaaaaaag tattattaac aaaatcaaaa
    18661 cgttcaaaaa tggaacagcg tggaaaattc atcagttttt tatgtatcgc gctgatcgtg
    18721 ttggttgtat tatctatttt ttattttgta gctagtaaag gattggccac cttttttact
    18781 gataagatca atgtatttga ttttctgttt ggtacagatt ggaatccaag ccaaatcgga
    18841 gcaaatggga aaccaatggt aggggcattg cctatgatca caggttcgtt tattgtgacc
    18901 tttttatctg ctatcgttgc cacgccattt gccattggtg cagcagtatt catgacggag
    18961 atctctccta aaaacggaac gaagatctta cagccggtca tcgagctgct tgtaggtatt
    19021 ccttctgtcg tttatggttt tatcggttta tcagttatcg tgccttttgt cagaagtatt
    19081 tttggcggga ctgggtttgg tatcttagct ggtacatttg tgttgttcgt tatgatcttg
    19141 ccgactgtca caacgatgac tgttgatgca ttaaaggcag tgccacggca ctatcgggaa
    19201 gcttcattag cgcttggtgc cacaagatgg caaacaatct acaaagtcgt gctacgagca
    19261 gccgtgcccg ggattttaac agcagtcgtt tttggtatgg ctcgtgcgtt tggtgaagcc
    19321 ttagctatcc aaatggtcat cggtaatgca gcattgatgc caacaggtct tactactcct
    19381 gcttctacat tgacgtccat cttaacaatg ggaatcggaa atacaatcat gggaacagtt
    19441 gaaaataatg tgttatggtc attagcgctg atcttgctat tgatgtcatt attctttaat
    19501 atcgtgatcc gtatgattgg gaagaaagga gagctgaaat aatgaacgca aaacgctcag
    19561 ataaaattgc tacaggtgtt ttatatatag tttcggggat catcgtattg attttagcag
    19621 ctttactact ttatatctta gttcggggaa taccgcacat ttcatggtcc ttcttgaccg
    19681 aaccttccaa agcctaccaa gaaggcggtg gaatcgggat ccagctattt aactcgattt
    19741 atttgctttt gatcacgatg atcatcagtt ttcctatttc tttaggtgcg ggtatctatc
    19801 tttcagaata tgctggaaaa aactggctaa cagatgtgat tcgcacgtcg attgaaatct
    19861 tgagctcgtt gccttctgtc gttgtcggtt tattcggttt cttggttttc gttattcaat
    19921 tccagtatgg tttctcgatt atttctggtg cattggcttt gactgtattc aacttgcctc
    19981 ttttgactag aacagttgag gagtctttac aagcggtcca ttacacacaa cgagaagcag
    20041 gattggcctt aggtttgtca cgctgggaaa cagtgataaa agtggtggtt ccagaagcga
    20101 caccagggat tttgactggt gtgatcctaa gttctggaag aatttttggt gaagcagctg
    20161 cattgatcta tacggctgga caaagtgcac ctgcgttaga ttttacgaac tggaatccat
    20221 taagtgtttc aagcccgatc agcattttcc gtcaagctga aacattagct gtccatattt
    20281 ggaagatcaa tacagaaggc acgatgcctg atggtgtttc tgtttcggct ggcgcttctg
    20341 ccgtgttgat tattgctgtt ttactgttca acttcggcgc tcgtgcgatt ggcaaacgat
    20401 tataccgaaa aatgacttca gcctaaggag aagaagcaaa atgaaaaaat ataactggaa
    20461 tgaaacaaat gtcatcacca tgccaaaaga gaaagaagta gcactatata cggatgatct
    20521 acatgtctgg tatggcgaca atgaagcaat caaaggagtg gatctggaat ttgaaaaaaa
    20581 taagatcact gcactgattg gtccttccgg ctgcggaaaa tctacgtatc ttcgttcgtt
    20641 gaatcgaatg aatgatggga tcgctaatac gaaaatcact gggaaaatca tgtatcaagg
    20701 cgtagatatt aatgcgcctc aagtggatgt ttatgagatg cgcaaacgga ttggcatggt
    20761 ttttcaacgt cctaatccgt tcagcaagtc gatttatgac aatattacat ttgctttgaa
    20821 acagcacggc gaaaaaaaca aaaagaaatt agatgaaatc gttgaaacaa gcttgaaaca
    20881 agctgccttg tgggaccaag taaaagacag cttggacaaa agtgccttgg ctttatctgg
    20941 cgggcaacag caacgtttat gtattgctcg tgcgatcgcg atgaaacctg atatcttgct
    21001 gctagacgag ccggcaagtg ctttggaccc tatttcgaca ggaacggttg aagaaacact
    21061 tgtaaacttg aaagaagact atacgatcat catcgtgacg cataacatgc aacaagcagc
    21121 tcgtatcagc gactatactg cctttttcta tttaggaaaa gtaatggaat atgacaaaac
    21181 taacaagata tttaccagac caaaaattca ggcaaccgaa gattatgtgt ccggtcattt
    21241 tggttaagac ggaggcctca acatgacaaa agagattatt tcatctaaag atcttcatct
    21301 gtattatgga aagaaagaag cactaaaagg gatcgatcta agcttcaatc aaggggaaat
    21361 cactgcgatg atcggtcctt ctggttgcgg aaaatccact tatctgcgtt ctttgaaccg
    21421 gatgaatgac ctgattccga atgtaacgat caccggaagt gttttatata aagacaaaga
    21481 catctatggt ccaaaaacag atgttgttga actaagaaaa gaaatcggca tggtattcca
    21541 gcagccaaac ccatttcctt tttctatcta tgaaaatgtc atctatggat tgaaattaaa
    21601 aggggaaaaa gataaaaaag tccttgatca agtagttgaa gaaagcctga aggcagcgtc
    21661 tgtttgggat gatgtgaaag acaaattgca taaaagtgct ttatctttat ccggtgggca
    21721 gcagcagcgt gtatgtatcg cacgtgtttt ggcagttaat ccggaaatca tcttattgga
    21781 tgaaccaaca agtgcgcttg atcctgtttc tactgggaaa atcgaaagta tgctgttaga
    21841 attaagagag cggtatacga tgatcatcgt gacccataat atgtctcaag cttcacgtat
    21901 ttcagataag acggcattct ttttagatgg tcacttgatc gaatacaatg atacgaagaa
    21961 gatattcatg aatccagaaa aacaagagac agaagattat atttcaggtc gatttggata
    22021 aggaggaaac ggaatgctac gtacacaatt tgaagaagaa ttgctgaatc tccataatca
    22081 gttctacgaa atggggatga tggtgagcag cgccgtgcac aagtcagttc gtgcatacat
    22141 caaacacgat aaaatcttag cccaagaagt tatcgaaaac gatataaata tcaataacat
    22201 ggaaacacgc ttggagaaga aaagttttga aatgatcgca ttgcaacagc cagttacaac
    22261 tgatttgcgt atgatcatta cggtcatgaa agctagctcg gatttagaac gtatggccga
    22321 tcatgcggtg tctgttgcta aatccacgat tcgcgtaaaa gggcagacga gaataccgga
    22381 aatcgaaaaa gagatctccg atatgtccga ttatgtgaaa aaaatggtgg acaacgtcct
    22441 agttgcttat gtcaaaacag acgaaaaaga cgcacgtacg atcgccaata tggatcaaag
    22501 agtcaatgac tatttcaatc gaatctataa tgcaacaatc aaaaatatgc aggaaaatcc
    22561 tgagacagtc atcagtggaa cagactactt gaatgttgcc agttatctag aacggatcgg
    22621 agactatgtg acaaacatct gtgaatggat cgtctacttg gctacaggga aaatcactga
    22681 gttaaatacg aaccacaatg agattttcta aactgaagct gtgattatgc cgtttgttta
    22741 ggaaaagagg ttgtgaaatc agcggttgtg aaaaagctgt tctgcatcaa gtaataagaa
    22801 cagtcaaaca aaaaatagct cctcatattt ttcgtttggc tggacttatt accgcagatg
    22861 caagcttttg aacaccgttt attcgggaaa gggtttgtga caaaacatgt cacaaaccct
    22921 tttcatcatt tcatagaaag gataaagaat gcaaaaaaaa attagcatca tcactatatt
    22981 ttttatttgt gtgcttactt catgggttat tcagcatcaa gccgctttat atgaagtacc
    23041 tgtcatcgag atagaaaaag tacgaataaa agaggatcat caattgatta caggaaaact
    23101 gatgaacacg gatcaaaaag gagaatcgat ttatttatcg gttccttatc aaaaaaatca
    23161 aatagaaaca gcaaatataa aagcgagaca aatgtatcta gtccaaatgc atggagatga
    23221 atggcagcta gtagcaaaaa aaaatgatgg ctggcttttc ttcttcacaa gtatcttcat
    23281 tggcgccatg ttgcttattg gtggaaaaca gggtctattt gctttaggaa gtctcatcat
    23341 caatatcgtt ttacttttac ttttgttgct catctttact aaaacagaag ggatttctct
    23401 attaaatata tctatcctgt tcgtcgttat agggatgatt attagcatat tggctttaga
    23461 tggatggaat agaagcagta taatcaaaat ttcagctgca gttacgagtg tttttttagc
    23521 attttttatt tgtcttttga caatgaatca ttggaaagac caaggactgc gctatgagga
    23581 actgaattat ctgacacgac cgtatcgttc tgtttttctt tctagcgtac tgattggaac
    23641 agctggagga acactcgata ccgttatcac agtcattgcg acattagaag aattgactaa
    23701 gcgacaacca gaaataacag cgaaacagtt atggctttca ggaaggcaag tgggtcgaga
    23761 tgtgattggc tcgatgacca atatcctttt gttcgtctat atcagtgggt cagttccatc
    23821 gcttctttta tatttaggaa atcaatggtc gttcaaagaa acgatagaac agcatttatc
    23881 attggaattt ttacgcgtca ttgctggcag cttaggaata gtattatcga tccctatctc
    23941 ggtcctcttt tttctgactg taaggaggct gaaacgatga atgtacttat tatacttgtt
    24001 gggattttag caatcagcgt gctacttatt ggcggtacgc aaggtatgta tattctttta
    24061 ggcttattca tcaatttagg gatctttttc ctgttgttat tcggttatca tcagaagtgg
    24121 ccgatactgg cattgtcggt cataggattt ttattgattg ctgtggttat cttatttttt
    24181 atcaacggtt ataatctaaa aatgcgtgca gcttttgtga gtatactgat ctttttattt
    24241 tgtttcctac tattgcttcc tatcactgat tttttagcaa tccaaggttt tacatcggta
    24301 gaactagaag aattatctgg cttagataag actttagcga ttgattttag attacttacg
    24361 agatcgttgc ttctgattag tcttagtggt gctgttttag atgcgagtgt agcaatttct
    24421 agtgggacat tcgaagtata tcaggcaaat ccgcaattat ctttttacca attgcgccat
    24481 tctagtttcg ctattgctaa aaaaatattg gcgtcaacag taatgacact tctttttgca
    24541 ttcatgggaa gttctttagc gttgatcctc tggtttattg atttagacat tccttttcag
    24601 caagtgatca atgaaaaatc atttgttcta gaatatacga tggctattct taccacattg
    24661 tccgcactac ttgttcttcc tttaacctgc gtgactacag catatctctt tacaaaaaag
    24721 aaagaacaac tcaagatgga gtaaaagtta caacttaagt cctatgacat ttttactgaa
    24781 tcagtgcata atatggatgt aaggaaaagc ttgcaaacaa ttttgcttaa ggaggcaatt
    24841 tccatgaaag aaagagaacg tattttagat ttagtgaaaa aaggaatcct ttcgactgaa
    24901 gaaggcttag atttattaga aagcatggca actgaaaaag acgaaaagca aatcaaaaaa
    24961 gaagcagaca aggtaactgc tagtcataaa gaaaaagatc aggcaagtca attgatcgat
    25021 aaacttgaaa acggcgaaga agaaatttct gagccagttg atccaaagga aagagaaaga
    25081 caagatcaag aaaacttaga aaagatctta gatgaactag caactgaagc gaataaaact
    25141 tcggcgcgtc tagatgaagt aaatgctcaa ttcgctgaca ataaggcagc acgcaatgag
    25201 aaacaggaag cattgatgca gctgaataca aaagaagaat taggcgagtt gacagaagaa
    25261 gaattagcac agcgtcagac gttagaagca gaaatcaaag aattagaagc tagtggcgat
    25321 acactgttag aagaacaatt gaaattagaa gcagaattaa aagatatccg taagaatcaa
    25381 tggtctgaga aaaaagaaac gtttactgat aagtttgaat tgccagatga ttggaaagat
    25441 caagcaacag atacactgaa tcaagtaggc gaaaaaatgt cagaagctgg atcacagtta
    25501 ggcaaattct tgaagaaaac attccaaact gtttcagaaa cagtgaatga caacatggaa
    25561 tggaaagatg tcagcttacg tgtccctggg attgcgacaa cgaaatttga gcatgaattt
    25621 tactatgaag ctcctgcagc aagtatcctt gatatcaagg cagcaaacgg aaacgtgacg
    25681 ttaaaaacgt gggacagcaa cgatgtgaaa gttgaagcta agatcaaact ttacggaaaa
    25741 atgggtgctg aaccatttga agcattctct gaacggagcc agattgaggt taatgaagat
    25801 catatctcct tccaaattcc aaataaacgt gtgcgtgcag accttgtttt ctacttacct
    25861 aaacgagtat acgaccacgc agctattaaa cttctaaatg gcaacatcat gattgaaaca
    25921 ttggaagcta aagatattta tacaaaatct acgaatggta acatcatcgt ggaccaatta
    25981 actgcaacga tgctggaagt agaaggtgta aacggcaata tcgatattcg aaacgggaac
    26041 atcttagatt ctattatcga aacagtaaat ggtacagtga catttggtgc gacagcagaa
    26101 aacctttctg tgtctttggt aaatggtgat gtacgtctta cgattaaaga agataatttg
    26161 aaaaaagtag aagcaagttc agtgaacgga aatgtcaaag tcgctttacc agatggcatc
    26221 ggtttggaag gacatgctaa aacaagtctt ggaagtatca acagccgtct gtccaattac
    26281 gaagtagttc gtgagaaaaa agaacggaca aaccaaatgt tgcaattccg tcgtgtttca
    26341 gatggtgaaa tcgcgcaagt gcaactttca acgacaacag gaagtatcta tttaaaagat
    26401 acagataaat aaagaggttg tgaaagagat gttcagcctt gagcaataag aagcgatttt
    26461 gtaaaatagc ttcccctatt ttacaaaatt gtgccttatt gccgatagtc tatctcttga
    26521 acaccgttta ccaagagatt atgaacctgc caattatcgc cgagtcacaa ggaataattt
    26581 cagaaaaagc tcgtcacgtt ttatgaatat ggtaatttgt gaccgagaat tttgcagaaa
    26641 gacaccgatt aagaagaagg ttgtcacaac gattttcttc atttaaaata gtagaacaga
    26701 ggtgagacat gatgaaaaaa aagttgacaa aatctaataa aaatgttgtt ttgacaggga
    26761 ctttagcagg aataggagaa tacatcggga ttgatccgac tgttatccgt gtgctttatg
    26821 tattcctgag cttagttgct tttggaagtc caattatttt atacatttta ttagctttga
    26881 ttatcccatc tgcgcgttct gcacgaacaa actatggaca taacaatgca tattatgaaa
    26941 aaaacaatta tcgtgaacaa actcgtgaac aaacaaaaaa acgcaaagaa gcggaaaaaa
    27001 tcgatgatga cgaatggagt gacttttaat gtcgtacttt caacgtattt tagttaatac
    27061 gttaacattc atatcattgg ctgttctttt tcctgcgatg gtccatgtga gcagtatttg
    27121 gacggccgtt cttgccagct tcgtattgtc tgtgttgaat atgtttgtca aaccgatttt
    27181 gacgatactg tccctgccct ttacattagt cacattggga ttgtttacgt ttgttatcaa
    27241 tgcagcgatt cttaaaatga cctccttttt tgtgggagca gaacatttta gtttttcttc
    27301 attcggtgca gcgttgttag tagctatctt gatgtcgctt gtcaatgtaa ttgtcagcga
    27361 acataacagt agaaaataaa agaaagctgt gccgaactat cggcgcagtt tttttattta
    27421 gaatcaggaa tgcgttttct attacattgg taattaaata aaaacgtttt ttttaattgg
    27481 tagtactttt ggctagacaa tgataaaatg atagagaaca ctctaataga aatgaggtag
    27541 catgaatgtc agaagttgta aaagttagcc aattagtgaa aaaattatct ttggaaatcg
    27601 tgacaggcga cgagaaaagc ttagaccgtg tcatcgtaac tggggacatc tcacgcccag
    27661 gactagagtt gactggttat tttaattatt attcccataa tcgtttacag ctatttggca
    27721 gtaaagaaat cagttttgcg gaacggatga tcccagaaga gcgtttgatc atcatgagaa
    27781 gattatgtag tgaagatatg cccgcattta ttatttcaag aggattacca gctccagaag
    27841 aaatgatcca ggcagcaaat gaaaatggga tagctgtact gcgttctccc atctcaactt
    27901 ctcgtttatt aggagaatta tccagttatt tagatggtcg ccttgcccct cgaacaagtg
    27961 tccacggtgt tttagtggat gtttacggat taggtgtact gattcaaggt gacagtggga
    28021 taggaaaaag tgaaacagcg ttggagttga tcaaacgcgg ccatcgattg atcgcagacg
    28081 atcgagtaga tgtttatcag caagatgaat taacggtgat cggagaaccg cctaaaatcc
    28141 tggaacatct gattgaaatc cgaggaatcg ggatcattga tgtaatgaat ctttttggtg
    28201 cgagtgcggt acgtggctct atgcaagtcc agttggctgt ttatctggaa gcatgggcaa
    28261 aagataagaa atacgaccgt ctgggctctg aagacacgac cgttgaaatc gcggaagtgg
    28321 gcattccaca aataaaaatc cctgtcaaaa caggacgaaa cgttgcaatc atcattgaag
    28381 tagccgcgat gaatttccgc gcacgtacaa tgggctttga cgcaacgaaa acatttgaag
    28441 aaagattaag tcgcttgatt gaagaaaact caggcaacga ctagcaagga gtgacaatat
    28501 gttagcacaa atcaatcgag ttgcttttga gcttgtaggg attcctatct actggtatgc
    28561 attgatcatc gtatcaggta tcattatcgc tatgtggctt agcagcagag aggctgttcg
    28621 ggtaggatta aaagcagatg atgtgacaga ttttatgttg tggggattgc ctatctccat
    28681 tattggcgct cgcttatatt atgttttatt tgatcttccc cagtatatag ctgatccaat
    28741 ccaaatattc aatatccgtt caggaggctt agctatttat ggcggactga ttgcaggcgc
    28801 gatcacgctg tattttttta ctaaatatca ttttatttct ttgtggactt ttttagatat
    28861 cgctgcacca agtgtattat tagcacaggc aatcggtcgt tggggaaatt tcatgaacca
    28921 cgaagcatat ggaccagaca cgacgcgaag cttcttagaa agtctgcatt taccgcaatt
    28981 catcattgat aatatgtata tcgaagggat ctatcgtcaa ccaacatttc tttatgaatc
    29041 actttggagt ttgattggat ttattttgct tttgttttta cgaaagaaac cacacctttt
    29101 gaaaaaaggc gaagtccttt tatgttatct aatgtggtat agtttcgggc gtttctttat
    29161 tgaaggatta cgtacagaca gtctttactt tttaggtgtg atccgtattt ctcaattatt
    29221 atctgctgtg ttatttgtcg gtacattgat tctatttatt tggcgcagaa aaaaaggaaa
    29281 tttaccggat tatgaccgct cattaggaaa aaatcaacaa attatctgat ttttagagcg
    29341 ttaaaaatga aaaaaatttc aggagtggta aaatgaatta tagagtagcg gttttaggac
    29401 caggctcttg gggtactgct ttggcacaag tcctcgccga aaacggacat gacgttcgga
    29461 tttggggaca tcgtgcttca caagtagaag aaatcaacac ccaacacacg aatcaacgtt
    29521 atttaccaga tcattatcta cccgattcca tccaagcatt caccaatatg gaagatgcag
    29581 taaaagacgc agatgcggtg ctattcgtca ttccaacgaa agcaatacgt tctgttgcaa
    29641 aagaactagt gcctaaattg aatacaaagc cagtgatcat ccatgcaagt aaaggattag
    29701 aacagggaac acataaaagg atctctgaca tcttgttaga ggaaatccca gcagaaaaaa
    29761 gaaaagctgt tgttgttctt tctggaccaa gccatgcaga agaagtagca aaacatgaca
    29821 tcactacgat cacagctgca agtacagatg caaaagcagc aaaatatgta caagagctgt
    29881 tcatgaataa ttattttcgg atctatacca atcctgatgt gatcggtgta gagatggggg
    29941 cagctttgaa aaatattatt gctattggtg ctggcgctat tcacggctta gggtttggcg
    30001 ataatgcaaa ggcagcaatc atgacgcgcg gattagctga gatcagccgt ttaggtgtag
    30061 caatgggtgc caacccgctg acctttatcg gattaagcgg aataggcgat ctagtcgtta
    30121 cttgcacaag tgttcattct aggaactggc gcgcaggcaa cttgttagga caagggcagc
    30181 ccctagaaga ggtgctagcc aatatgggaa tggtcgttga aggtgtgaat actacccaag
    30241 cagcgatgga actagcccaa atgatggaaa tcgaaatgcc catcactcaa acaatctatg
    30301 aagtgctgta tgaacaaaaa gaaatcaaaa cagccgcaaa agaaatcatg ttacgtgatg
    30361 gaaaaaaaga aaatgaattc tcattaacaa ttttttgaag gagcgaatgt atatgaaagt
    30421 taaaaaagca gttattccag cagcaggatt aggaacaaga tttttaccag caacaaaagc
    30481 tatggcaaag gaaatgttgc caattgttga taaaccaaca atccagttca tcgttgaaga
    30541 agcgttgaaa tcaggtatcg aagacatctt gatcgttaca ggaaaagcta aacgaccaat
    30601 cgaagatcac tttgattcaa atattgaatt agaaacaaac ctaagtgaaa aaggaaagac
    30661 cgaattattg aaattagtag aagaaacgac agatgtcaac ttgcatttca tccgtcaatc
    30721 tcatccaaag ggtttaggac atgccgttct tcaagcaaga gcctttattg gaaatgaacc
    30781 atttgtcgtt atgctaggcg atgatataat ggaagacgaa gtaccattga cacagcaatt
    30841 aatcgatgat tacgaacgta ctcatgcttc tacgatcgcc gttatgcaag ttcctcatga
    30901 tgaaacttca aaatacggaa ttatcaatcc aggagaagta ttggaagatg ggttatacaa
    30961 tgtcaaaaac tttgttgaaa aaccagatcc aagcaaagca ccaagtgatt tagctattat
    31021 tggacgttac ttattgactc cagaaatttt tgatgtattg tccgagcaac aaccaggagc
    31081 cggaaatgaa atccaactaa ctgacgcaat cgatacattg aataaaacac aacgcgtatt
    31141 tgcccgtaaa ttcacaggta aacgttacga tgtcggtgac aaatttggtt ttatgaaaac
    31201 aagtattgaa tatggtctaa cacatccaga agtaggtgca cctttacgtg agtacatcct
    31261 gtctttaggt aaaacattag aagcagaagg aagcaagatc gatcataatc caaaaggaat
    31321 aacagaaatc aaagaagaaa agaaaaaata accctttttt ctaacgagct tcagctgcta
    31381 attgaataaa aagtagttga agctcgtttt tatttgttta aaaaacacga aaatgctatc
    31441 cttatagaaa agagagacaa gaagggagtt tgatcatgtc aggaggagaa attgcaggat
    31501 tgatcgcagc aatcgccttt gcgatacttg tcgtttttat cgttcgtgtg ttgttgcaag
    31561 tttctaaaac tttagaaaaa gtagatcaga ctgtagcaga agcaaatacg acgatcgaaa
    31621 tcgtcacaaa agacgtagat cttttgtcta gacaagtaga aggcttactg gtcaaaagta
    31681 atgaactgct cttggatatc aatggaaaag tcgcaacgat cgatccattg ttcacagcag
    31741 ttgctgattt aagtgaaagt gtatcagaac ttaatcattc tagtaaaaac atcgcgacga
    31801 aagtcggcgg aatcggtaaa acgacagcta aagcgacggt tgccggaaaa gtcggtggga
    31861 cagcgatgaa attttttaaa aacaaaaaac atactgaaac gacaggagga aaataaaaat
    31921 ggctaaaaaa ggtggatttt tattaggtgc agtagtcgga ggcacagccg cagcaatcgc
    31981 cgcgttattg ttagcaccaa aatctggtaa agaacttcgg gatgaattag ctgcccaagc
    32041 ggatgatttg atggatatgg cttcagatta cacagatatg gcgaaagaaa aatcgactga
    32101 gttaacaggt attgcaaaag aaaaagcgca agatctttct caacaagcag gtgatctagc
    32161 aggtagtgtc aaacaaaaag taagtgaatc agcagatgaa gcaggaagtg aatctgacga
    32221 tatcttgtta aatcttaaag aacaatcagc tgacttatct aatcgtttca aaaaaacggc
    32281 agaagatatg aaaaaacctg cagatgaatt aggaagtatt gctaaagata cttcagaaga
    32341 tatcatgatt gatgtaaaag acgctgctgg taaagcagga gatactgtca atgaaggaat
    32401 gtcagaagca aaaccagttg cagatgactc aaaagaaatg atgaaaatgg caaaagaaga
    32461 tgcgaaagaa gctaaaaaag aaataaaaga tacaatgaca gattcatcta caaatcacta
    32521 aaatcacaaa tttatagaat aaaaaggtgg gagcggacta gctctcacct tttttactct
    32581 tatttttcta aaacaagtaa ttcttttggt gtagtcgtga atggcacaca gccatcgctt
    32641 gtcacatata cacagtcttc gatacgtacc cctacttttt caggaatata gattcctggt
    32701 tcaagagaga agcacatccc ttcttcgatt actaagtcat ttccttctac aagggaaggg
    32761 aattcgtgga cggttgttcc gatcccgtga cctaaacggt gattgaaata ttcgccgtag
    32821 ccatagctgt tgatcacgtt tcgtgcgatt tgatcaagtt cacctgctgt cacacctgga
    32881 cggacggctt cttgtgcggc aagctgtgct tcaagagtga tgttgtagat tttttcttgg
    32941 aagtcggttg gtttttgata agcaattgta cgagtagcat cactgcaata gccattccaa
    33001 acaacgccaa gatcgaataa cacaagttca ttcggtgaaa tcttcgtatt tcctggtgta
    33061 ccatgagggc ttgcagcatt tgctcctgca aggactaatg tgtcgaaaga catttgtgaa
    33121 acaccttgtt ttttcaattg gtattcaatt tctgcaatga tcgcttgttc agtcacgcct
    33181 tctttcactg ctttaaagcc aatctcaaat gcaacatcgg cccatttacc agcttcgatc
    33241 agtttgtctt tttcctctag agttttgatc agttgtagac gttggatgat ggaagttaga
    33301 tcagtgtaag aatccgttcc cgtcaagata tcagagatag catcgaagcg ctcgacagtc
    33361 aaggcgttct tttcaatccc tacattgcca ggctgaccat agcgagcacg aagttctttt
    33421 ccgatgatct cccaagggtt ttcgctgtct aaatagccac ggacatcata cgcccaacta
    33481 ctgttttgag catcttcaac ttccaaagca ggagtgaaaa ggaaaggatc ttgttcaaga
    33541 gggataaaaa gagctagtac acgctcatga ggatcacttt cgtatccgga aaagtaagcg
    33601 atgtggccag ggtcgctgat ataagccaat tcgacttggt gttgtgccat ccattgacgt
    33661 agttcattga tttttacgtt attcatttgg caacctactt tctaaattaa ttttgtattc
    33721 aataattgta ccactgattt attaaaagac caacgttcta aaaactgaaa aaagtaaaaa
    33781 ttttcatgaa aacagagata aaacggttgc aattcttgag attatttgat attctatttt
    33841 agaaatgtaa gacgtatttt cagaaaacat ataaaatatg aataggagaa cacaaatgga
    33901 aaagcaaaca atcactatct atgatgtagc gagagaggca aatgtttcga tggctactgt
    33961 ttcacgtgtc gtaaatggca atccaaacgt taaaccagca acaagaaaaa aagtcttgga
    34021 agttatcgat cgcttggatt atcgtccaaa cgcagttgcg cgtggcttgg caagtaagaa
    34081 aacaacaaca gttggtgtaa tcatccctga tgtcagcaat atgttctttg cttctttagc
    34141 acgtggtatc gatgatgtgg caacaatgta caaatacaat attatcttag caaattcaga
    34201 tggcaacgac caaaaagaag tcaatgtatt gaataactta ctggctaagc aagtggacgg
    34261 cgtgatcttc atgggtcacc atatcacaga cgaaatccgt ggagaatttt cacgttcaaa
    34321 aactcctgtt gtattagctg gctctattga tccagatgaa caagtaggta gcgtaaacat
    34381 tgattatgta tccgcaacaa aagatgcagt aaacaaattg gcaaaaagcg gcaataaaaa
    34441 aatcgctttt gtcagtggtg cgttgatcga tcccatcaat ggacaaaatc gtctgaaagg
    34501 ctataaagaa gcattaagcg aaaataacct accatatagc gaaggattga tctttgaagc
    34561 acaatacaac ttcaaagatg gtctatctct agtcgatcgg atccataata gcggtgcaac
    34621 agctgtctat gtttcagatg atgaattagc catcggtatt ttggatggtt tattagaccg
    34681 tggcgtgaaa gtaccggaag aattcgaaat catcacaagt aacaattcac tactgacaga
    34741 agtagctcgt cctcgtttaa caagtatcac acaaccatta tacgatttag gggcggtatc
    34801 tatgcgccta ttgacgaaaa tgatgaataa agaagaagtc gaagaaaaaa cgattatctt
    34861 gccttatgga atcgaagaaa aaggatctac aaaataataa aaggacaacc attcagaggt
    34921 tgtgtgcctg ccgtttaact ctgcgttaca aggagcaatt tcaaaaaaca gcatctcatg
    34981 tttgatgaat attgtgactc gtgattcgga gttggcagga gaacaccgtt tatttgggaa
    35041 aaggggttat gacaaaattt tgttataatc ctttttttgt gtcttaaaaa agagagaaag
    35101 tggttgaaat tacatttatc gtatataaaa caatccgtgt atagatgctg cattttgttc
    35161 accaccatca aaaaaataag ggactgtgac aatactattg tcacaatccc ttattactgt
    35221 gtattctatt aaatcaatca tctttctcat ctgattcttt agttgcttga ttcgctcttg
    35281 cataagctga agcggtgttc cagtaatctg tatagttttc atcggtaccg ccaacgccaa
    35341 atttaaaggc gcttttcttc ggtccatttt tcgcccatag cgattcaact gtttttcctg
    35401 gtgtttggat ggatttttta ttgacagtaa cttttccagg tgtttgacca gtaaatccag
    35461 atactttttt cttcatcaca tcagatgata attcgaattt ctcatcagtg ccaaaaatgt
    35521 caggttttgc ttggtaagct tgattgatca gattggcaag ataattagcc gaacgtatcc
    35581 ttgctttgct gtccattcca gtattgtcat cgtgccctgc ccagctactg atggtaatag
    35641 acggagtaga gacaattagc catgaatctc ggtattcatt ggtagaacca gtttttccga
    35701 cccaatctgc ttttcctaga tttccgttta agcttgagat ggcatctttg aatggtgtag
    35761 tgatttttgc attgatcaca ctacgcatca tgtcattcat gatcgatgcc gttgcttccg
    35821 aatagatccg gacagagttg ctttcgtgtt tataaattac atttcctgcg ttatctgtga
    35881 tggaatcgat gatatagcct tcttcataga cgccgccgtt tgctaaagcc tgaaatccgt
    35941 tggtctgttg aagcgtcgtg acatctactg tacctaaagg agcagattca acgccccaat
    36001 tgtcatttgc cgggtagttc atctttgcca agtagtgctc gtaagcatat tgtttcgatc
    36061 caccggaatt caacacatct tgatataagt gataagccgg gatattgttg gaccattcta
    36121 gtgactcacg gacggtttgg aaggtgttcg atccttcgtt agtagcattg acgattttct
    36181 cgccagcatt ttctccttct tgccaagttg ttgcataatc tgatacacgg gattctgatc
    36241 cgataagccc catgtcgatt gcaggtccat aaacaagaac tggtttgatt gatgagccag
    36301 cttgacgttc tgtatcgaag gcatggttat tttgattctg actgtaattc cgtccgccaa
    36361 cgaatccgta gatgcggcca gttctgttat ccatcaatac atttccggtt tctacttgac
    36421 tgccagcacc atcatctaac atgtatccat aattttcaac gccattttgc aatgcagcat
    36481 agacatcttt atcgattgtc gaatggattg tatatccttt attttggatc gtttgctgtg
    36541 ccttttgata ataagcgtca ctgaccgatg aatcagacat atcagcgttg tctttttcag
    36601 ccaattgttg tgcaatgatt cttgttgctt cattcatcac agtataatac aagaattctc
    36661 tgtcagtctg ttctgcgatt tgttgtggta gaaagtcttt tgtaaggtca taggcttttg
    36721 cttcttcgta ttgttctttc gtaatttggc cttcacgata catactgaat aaaacaaaat
    36781 cttttctggc aaggccggca gaaagatctt cttttagcgc gcctgtgttc gtgtatggac
    36841 tatacgtgat cgggctttgg ggtaatccag cgatataagc agcttgcggc agcgtcacat
    36901 cttttgcatc tacaccaaag attccttttg cagcttcctg gactccagca atgttttgtc
    36961 ccttattatt acgaccaaat ggtgagacat tcaaatacgt agcaatgatc tcatcttttg
    37021 aaaagtattt ttctacttgt gcagaaagaa tgatctcgtt tgctttacgt ttgaatgttg
    37081 tttcatctgt aaggatctgc tgtttgacta attgctgtgt caaagttgat ccaccagaag
    37141 agccaatacc agtagcttca gatactaatg ctcgtaaaac agctttagga acgtaacctt
    37201 ggtgtttatc gaagtattca tcctctgtgc tgataattgc agttttcaat aaaggtgaaa
    37261 tcttatcaga tgaaatagtc gtgcgcatca gatctgtctg gatttttgat atctctgtat
    37321 tatctgcata aacaatcttt gacgtttctg taatgtttcc tagttctgtc tgcagtgctt
    37381 ttttagtcgg caattgtgtg tcttcgacga gataggcaaa atagccagcg cctattccaa
    37441 tacctagagc tgcgaacatc aaaagaagaa cagtaataaa aacagtcaat gattgaaaaa
    37501 ctctaaaaat aatcttagga acaaaccatt tttctttttt tcttctattc tgtttttttc
    37561 gagtattttt gcgtggcaaa agggtcacct caactaatgg ttttatttcg ctaattatag
    37621 caaataatag aacaaaaaaa cagacaaggc tgtttttggc aggaatttct tttttaaaag
    37681 agttaaaacg tgagaaaatg atctttatta taaaagagtt cttaagcttt tctttagaga
    37741 aaatttcagt tactatggag aacagggcaa agaaaaatca atcattttct ttgtatatca
    37801 tcttaccaat atataggaat tgttagtaac aattgccttt caaggaggaa tccatccatg
    37861 ttattaggct cacacgtcag catgagcgga aagaaaatgc tgttaggagc agcagaagaa
    37921 gcagccagtt atggatcttc gacttttatg atctatacag gcgcccctca aaacactaga
    37981 agaaaagcca tcgaagagat gaatattgat gccggaaaag cgtacatggc agaaaaaggt
    38041 ctaacaaata tcgtcgttca tgccccttat atcattaatt tggggaatac gatcaaacca
    38101 gaaatgtttc cttttgccgt ccaatttctg agagaagaga ttgttcgtgc ggaagcttta
    38161 ggcgctactc aaattacact tcacccaggt gctcatgtag gggcaggaac agaagccgga
    38221 attgctagaa ttattgaagg cttgaatgaa gttttgacaa aagaacagac ggcacaaatc
    38281 gctttggaga caatggcagg taaaggtacg gaaatcggtc gaacatttga ggaattagcg
    38341 caaatcatcg atggagtaaa attgaatgaa aaattatccg ttacttttga cacctgtcat
    38401 acgaatgatg ccggttataa tattaaagaa gacttttcag gtgtaatgga agagtttgat
    38461 aagatcatcg ggttagatcg gcttaaagta ctccatatca atgattctaa aaatccgcaa
    38521 ggttcgcata aagaccggca cgccaatatt ggttttggaa caatcggatt cgacacgctg
    38581 aataagatcg tccatgatcc aatgtttgac aatatttcga aaatcttgga aactccctat
    38641 gtaggcaaag ataaaaagaa agcttacgca ccatatggaa aagaaatcgc catgttcaaa
    38701 gcgcaaacat tcgatccaga agtgtttcct gagttattag cagaagaagt gatactctaa
    38761 gattttctat ctgacagcag caaaaaagga ccaggcacat tgccttgtcc ttttttgttt
    38821 aagaaacaaa ggagtacttt ttgcagtctt tttcatcatg catcttctcc cccctctttt
    38881 taaatttaga caaacaaggt atactggtag aaaagtaaaa aaacgaaaag tttcacaagc
    38941 aagtggcaaa acgtgattgg aaggacgaaa agatgctgaa cactttaaaa cccttgatca
    39001 accaactaaa aaagaaacat acatacttta ttcttggcat agccctatta tttacaatta
    39061 ttcgtttgta tttatatagt aaagcaatct atggaacaga catgtcggca acctatgatg
    39121 accagctgct gattcgctat gctcaaaata ttttggacgg taaatggcta ggggagtata
    39181 cgactacaac actttccaaa ggaatctcct acagcttatt tttagtactt gcacataaac
    39241 tgcatctttc ttatgcagtt ttgttcggca tgttcagtat ttttgccagt atattggttg
    39301 cactcgcgtt taaaccgatt gtgaagaaca agtatcttct tttaagtatc tatttttatt
    39361 ttttgttttc tccgattagt tttacacatg aatattccac tcgaacatat cgtaatgccc
    39421 tcgtgattcc ggctgttgag atcattatcg cttgtttatt agctatttat taccgcaaat
    39481 acggttctag cagaaaattg ctgccatggt ttttagggct ttctgtcgct tttcctttct
    39541 tttggttcat tcgcgaagat tctatctggc ttcttccttt tactgtagta gctttgggta
    39601 tcagtttcgt ccagatcttg ctagggcaag acttttcttt caaagaagta aagaagttaa
    39661 aaaaacgact ctttcttctc tcgaaacggg aatggctgaa actttcattg tttttacttc
    39721 ctatagttgg cttttccatc gtctatcaat ggatcgaata taaaaatgag acaacatacg
    39781 gtattgcaac catcaatgac cgttccagtg gagaatttgg acgtttgatg aaacaactga
    39841 tccgaataga tgatgaaacg aacttgaata aagaaaacag tgagatatgg gtctcacatg
    39901 ctgcactaaa taaagcatta gccgcatctc ctacattcca tactgtttct acccgtattg
    39961 acgaattata tacgactcac gcgtggactc aaggtggaaa agtaaaagaa ttacccggag
    40021 atatcatctt ttgggcattg cgagatgtgg taagcgaatc tggttattac caaaacaatg
    40081 caaaagaaac caatgatttt tggaaaaaag tcaaccaaga attagaagaa gcctatcaca
    40141 agggaacaat caaaaagaaa aaagagttct atctgatggg atcaggagat ggaaagacga
    40201 tgagtgatct gccaatcgta ttcgatttcc ttcaatcagg atacgcttat gcatggcgat
    40261 ataaagattt ccatcaagga ggaaattata gtttcggaac gcaagaacaa gtcaaacagg
    40321 ctcaagaatt attaaacctt ccgctaatgg agaattggat cgatagtaat gaaccgagaa
    40381 cacctaattt ccaattaaca aaatcagcaa aagtcgcgaa tgtcatcata aaaatttacc
    40441 aagttctggc tattcccgtg ctgattgctt caatagcagg gatattactt atgatactag
    40501 gaaccgtatt tgcaaaagct gatcgtgcct attatagttc ctctttgatt gtggtcaccg
    40561 gattaatact gacacaattg gtttttcttt tcggtgtctc atggttttgt tcttatgcgc
    40621 cagaaaaaaa ggactatttt ttaagtgtct acactggtgc aggcgtgcca ttaacgcaat
    40681 tcatcgtagt aacaagcatg ctagttttca gtaaattaaa tctgaaaaaa gctttatctt
    40741 ctaaataaaa agacccttgg tagctagatt tttaacctaa ctatcaaggg tctttgtgtg
    40801 gaaaaatcag tttttattcg atttcttcta ccgtttcctg caaaagctgt tcatattttt
    40861 tgtttccttt atataaatca ccaatcgtcc atgccaacag gagaaggaca agaacaatga
    40921 ttacataagc gatgtgatca gccaatgcta gttgagcgga agtggcttgc tcgccgaaga
    40981 aactttcgat ctgtcctggt aatcctcgta agttcaagta agttagacta atcacagaga
    41041 accagccaag aagttttacg atgaatgaat ttttaaatcg gctacccatc tccgcttggc
    41101 tgttggtcat catcagtaaa ggaatcatcg aaaacggcaa cgcaaaagcc aagaacacct
    41161 gggattcatt cattaagtta ttcaaagcgg catgttcttc gatcgttcct tttgtacttg
    41221 taaacaaaac acaaatcaat acaggaatca cagaaagcaa tcgtgtgacc agtcttctta
    41281 gccaaatcgg gatacgcata tggatgaatc cttccatgat gacttgaccg gtcaacgtac
    41341 cagtaatagt agagttctgg ccagaagcaa gaagtgctac agcaaataaa gtggacaaga
    41401 taccagattt tgctacagca atcaaaatac cattgctcat agctgatgga tcagataaag
    41461 cttcatacag accaaaaaag gaaggatctt ggacagaacc ggttttgaag acagcgacac
    41521 ccatgatcaa tagcagtgca ttgactagaa aagccattga caactggata ttagaatccc
    41581 aagtagaaaa acgtacagct tgtgctacat cttcttcgtt ttggtgatcg atcttccgag
    41641 tttgtgaaac tgctgaatga agatataagt tatgcggcat gactgttgca ccaataatcc
    41701 ctaaagctcc agtcagcgga gtttcgccgc cgatgaccgg tgagtctgag aatgtatgac
    41761 tgttagggat aaagccagca aataaactgt gccaatctgg gttagacaag ccaacttgat
    41821 agacaaaaac gaataaaatg acgaaaatta agcagacaac cagtgcttcg atcttacgaa
    41881 acccgacttt tgtcagtagt aagagaacga aaacatctaa tacagtaata aagacggcaa
    41941 tcaccaatgg aatatcaaaa agtaagtaga gggcgattgc tgcaccaatg acttctgcaa
    42001 tatctgttgc cataatggct aattcagtca agatccataa aatgacacct aatgtcttac
    42061 ttgtgcgtgc tcggattgcc tgtgccaaat ccatttggct cacgattcct aattttgctg
    42121 ccatatactg taaaagcata gcaatcagac tagacatcaa aataactgac atcaataaat
    42181 attggaaatt ttgtcctccg gtgatcgaag tagaccagtt acccgggtcc atatacccaa
    42241 ctgctactaa cgcaccaggt ccagagtaag caagaagtgt tttaaaaaaa cttttcccct
    42301 ttggtacatc aactgttcca tttacttcag ctaaagataa accatttgta tgttcaataa
    42361 gtcgatgctt atgaaattgt ttattggatt gattattcaa gaaaaaacca cctttcctat
    42421 ttatctacga ttacattcta cacctcaaaa agaaaaaatt aaagaaaaag attcggtacg
    42481 cctaattttt tttcatggcg cgtcttgcta gatgacgaaa gaaattttgt tctcctctaa
    42541 aaaaaccact attttttgca tgaaactaaa gaatacgcct ttcttttttc aataaacttt
    42601 agtaaaataa gtcattgaga gcaattcgga aatagaaagg agagatttat atgttatcaa
    42661 caggtattgt cgtacttatt gctattattg ctttgctaat cggcgcagta ggtggctttt
    42721 tcctagcgcg taaatatatg aaagactatt tagaaaaaaa tcctcccgtt aatgaggaca
    42781 tgttgcgatc aatgatgatg tcaatggggc aaaaaccatc tgagaagaaa attcgccaga
    42841 tgatgcagca aatgaagaac caagggaaaa aataggttct gacccaacga ctttttacgg
    42901 gctgattttt tcagtccgtt ttttatttcg taatttgtta gactattcag attattcagc
    42961 aaaaaagaca agcacagaca atcctaggct cttgataaag acaaaggagg agtaaaatgt
    43021 cgatttttag aaaattaggc tggttttttc gtcaggaaaa gaaacattat ttaattgggg
    43081 ttttctcgct attcgcagtg gccttggtac agttagttcc tccaaaagtg attgggatca
    43141 tcattgatga gatcgccgat aaaaatttat caataaagat cattttcggg tggatcttcc
    43201 tattgattat cgctgctttt ttacaatatc tttttcgtta tatctggcgg acgaatattt
    43261 ggggaagtgc agctcgattg gagaaagaac ttcggcagca gttattcaaa cattttacag
    43321 aaatggacaa tctcttttac caaaaatatc ggactgggga tttgatggct cacgcaacga
    43381 atgatttgaa tgcgatccag aatgtagcag gagctggtat cttgaccttt gcagattcag
    43441 tgattacggg cggaacaacg atcattgcga tgattttgtt tattgattgg cgcttaacac
    43501 tgattgcgct gattcctctg cctttgctgg ccgtcacttc acgagtgctg gggtcaaaac
    43561 tccatgatgc ttttcgtgat tcgcaagaag ctttttctag tatcaatgat aagacacaag
    43621 aaagtatcac tgggatcaaa gtcattaaaa catttggaca agaaaaagaa gatctagcgg
    43681 attttgaaga aaagattgaa gatgcaatta ttaaaaacaa acgagtcaat tttttagact
    43741 ccttatttga tccattcatt accttgatta tcggtctgtc ttatgttgca acaattattt
    43801 taggtggaaa gtatgtcttg gaaggcacga tctcgatcgg gcagatggtc tcatttatta
    43861 gttatatcgg tatgcttgtt tggccgatgt ttgcgattgg tcgattgttc aacgtattgg
    43921 aaagaggaaa tgcttcttat gatcgcgtca atgaactttt gcatgaaaag acgcatatcg
    43981 tggaacaact gggtgcagtg cagaccccgg caaaaggcga gctgaatgta gctatttcct
    44041 cttttaatta tccgaaagaa gaatcaccag cattagaaca aatcaagttt gcgatccaag
    44101 aaggagaaac attaggtatt gttgggaaaa ctggtgcggg aaaaacgacg atcatcaaat
    44161 tactgatgcg tgaatacgat gattatcaag ggaaaatcca atttggcgga cgttcgatca
    44221 aagaatattc attgaatgct ttattaggat caatcggcta tgtgcctcag gatcacttct
    44281 tgttttcgat gaccattcga gataatatcc gtttttctaa tccaaaactt tcagaagaag
    44341 aagtagagca tgcggcttct ttagcattta tcaacaatga aatcaaggaa ttaccaaaag
    44401 gttatgatac cttagttgga gaacgtggag tctctttatc tggcggacag aaacaaagga
    44461 tttcgattgc tcgagcattg atcaaaaatc ctgaattatt aatattagat gatgcactct
    44521 ctgcagtaga tgccaaaaca gaagaagcta tcttgcataa tttaaaagaa ataagaaaag
    44581 agaaaacaac tatcattgca gctcaccgtt taagtagcgt gatgcatgca aaagaaatca
    44641 ttgttgtcga tcaagggaaa atcattgaac gaggaaccca tcatgagctg cttgcactag
    44701 gcggctggta tgaacaaatg tgggagaaac agcaattaga agcgaagata gaaggaggcg
    44761 aggcctgatg gatgaaaatt atcaatcgga atggacaaaa tcgattccac ttaaagaaca
    44821 gaaaaagatc atcaaacgac tgatgaagtt cgccaaacct tttagaagaa cgttcatcgt
    44881 tgctatctta tttgcgtttg ctttgtctgt gatcaatgtc ctattgccaa ggatcatcca
    44941 aacttttatg gatgatcatc tggctaaaca gtcggctacg acacaagtta ttttgttttt
    45001 tgctggtatg tacttatttg gagtcatagt aaaaagtatc atttggtttt tccaatggta
    45061 tttgtattcc atggcctcat tgaagaccta tcagtatatt agggtaaaat tatttgaaaa
    45121 gctgcataca ctaggtatgc gttattttga tcagacaccg gcaggatcaa ccgtttctcg
    45181 agtgacgaat gacacagaaa cgctatttga attttggtac gtctttttga tggtattgac
    45241 tgggatcttt gcagtcgttt cttcattcct tgccatgttt caaatcaatg gagaaattgc
    45301 cttgtggact ttggtgtttt tgccgatttt aggaatcgtc atctggtatt accagaaatt
    45361 cagttctcgt atttaccgaa atatgcggga aaaattaagt cagctgaaca cgaaattgaa
    45421 tgaatcgatt tccggcatgc gtattatcca gcagtttcgc caagaagctc gtttagctaa
    45481 agaatttgaa caagtgaaca atgagtattt agacacgcgt tatgcgatga tcaaaacgaa
    45541 ttcgattctg ttaagtccga tcatcaattt tctatatgca ttggcgattg cgttggtgtt
    45601 gactttgttt gggatcgatg cgttgcattc tcccgtagaa gttggactga tctatgcatt
    45661 tacgacctat gtccagggat tttttaatcc aatgtctcaa atgatggact ttttgagcat
    45721 cttcacagat gggatggttg ctggtagtcg tatcttgaag attatggata cggaagaata
    45781 tgcaccacaa caaaaccctg gagcagatca aatgattact tcaggtaaga ttgagtttcg
    45841 caatgtaagc ttttcttatg atggagagca caatgtatta aacaatatct cttttgttgc
    45901 taatccggga gagaccgttg cattagtggg acacaccgga agcggaaaaa gctcgatcat
    45961 caacgtattg atgcggtttt acgaatttta tgaaggtcag atattgattg atgatcatga
    46021 cattcgagaa tatccaatgg aagagttacg taagaaaatg gggctggtct tgcaagatgc
    46081 tttcttgttt tatggggata tcgcaggaaa tattcggatg atgaatccag ctatcacaga
    46141 cgaacagata cgccatgcgg ctgagtttgt tcaagcaaac aaattcatcg atgaattacc
    46201 aaaaggatat cactcaaaag tgatcgaaca tggtgccagc tattctagtg gacaacgaca
    46261 gctgatcact tttgcgcgaa caatcgtgac tgatcctaaa attctagtat tggatgaagc
    46321 aacagcaaat atcgatactg aaacagaagg attgatccaa gaaggattgg caaaaatgcg
    46381 tcaaggacgg acaacgattg cgattgccca tcggctgtca acgattcgag atgcagaatt
    46441 gattttagtt ttagacaaag gtcatatagt agaacgcggg aatcatgaaa cacttctagc
    46501 gcaaaatggt ttgtatgcag atatgtacaa actgcaaagc agtggtatat aaaagatgtt
    46561 gtgacagtag aattttgacc taagcactag agtgaaaata aaacatagct tctcatattt
    46621 ttcatctgtg agagttagtg tcgtagtcac cagatttaaa aaaagattcg acagctagtc
    46681 agaagtgcct aatagccact aagaaagcgt tgacaaaagc atttgctttc gataatataa
    46741 agaaaacgat acaacttgga tagtgattgc ctgatgcaag ctaaacctga tgagtctccc
    46801 atggtttcat ggacggcttt ttgggttttt ctttttgttt tggatacagc cctatacatc
    46861 atggaaagga gcaaaacatg ctgattgaga aagtactgaa taacaacgtc gtaataacca
    46921 gggatgaaag aaatcaggaa atgatcgtga tgggaaaagg tttggcattc aaaaagaaag
    46981 tgggtgaccc gatttttgac tcatgcatcg acaaaaaatt tcagttgaca aatgacgggc
    47041 tttcacaaca gttccaagaa ttggcacaag cgattcctct tgagtactta gaaatttctt
    47101 gtgaaatcat tgaatataca aaagaggctc tacaagtcca gttgaatgat tctgtgtata
    47161 ttgcattgac ggatcatttg tatacggcta tcgaacgtca caaaatggga atatttgtac
    47221 caaatgtatt gctgtatgat atcaaacaac tatttcctaa agagtatgcc atcgggaaaa
    47281 aaacagtgaa gaaaatctcg gataaatacc acatcaagtt atcagaagat gaagccggat
    47341 ttatcgcatt gcatttagtc aatgcacaag gcattcaaag ccagcaagac aatacctacc
    47401 tgtttactat aacaatacag gatattctaa atatcgtccg ctattactat aagattacat
    47461 ttgatgaaga ttcagtccat ttttttcgat tcgtcacaca cttacgtttt tttctgacac
    47521 gcgtcctaga tggagaaaaa tcagaagtgg gagaagtttc tgaggaattg tttcaggtta
    47581 ttcaaaaaaa atataaggat acgtttggtt gcgttgagaa aatagcagac tttttagccg
    47641 agacgttcaa ctaccagatg tccacggacg aaaaaatgta tttaacgatc catactgcgc
    47701 gtttagtgca tgagaatcgt tgtaaataaa aaaaggagga taaattaaca agaacgtatg
    47761 aaataagggt agtgacattc agttggctaa accttccact aataaattgg agggaataga
    47821 aatgggaaaa taccaagaat tagcgagaaa aatcgtagaa aatgtcggcg ggaaggaaaa
    47881 tatcaatggt ttgacacatt gtatcacaag gcttcgtttc aaattaaaaa acgaagaaaa
    47941 agcaaatgat gagatcttga aaaatatgga cggtattgta acggtaatgc gagcgggagg
    48001 gcagtatcaa gttgtcattg ggaatcatgt gccagtcgtg tttgaagagg ttataaaagc
    48061 aggaaacctt acttttgatg aggctgtttc aacagaaaaa atgagaccgt ttgatatgct
    48121 tattgatgga atatcgggct gtttccagcc attccttgct atcctagctg ctggcgggat
    48181 gattcgtgga ctgacagcat tccttgtctt cttaggcgcg tttgaccgcg gttctggcac
    48241 atttgttatg tttgataata tcggtgattc tgtattccaa tttatgcctg ttattatcgg
    48301 tttaacagct gcccgtaaat ttaaagtaaa tgaattcgta gggatgttgc ttggcgcagc
    48361 attaatgaat cctagcttgt cgctggaagc tttgagtggt gcagcagaag caccactaac
    48421 gaccatattt tctggcacta tttttgaagc acctatttat caaacagtat tcggcattcc
    48481 ctggattgcg cgtaactacg cttcttctgt cattcccatt atctttattg tgttgttagc
    48541 tagccaaatt cagaaaccaa ttaaaaagtt agtacctgag atgatcgcga atttcttcgt
    48601 tccattcttc accgttctta ttacaatgcc tttaggtttt ttactcgttg gaccagtatt
    48661 cacattcgca actgatattt taatggctgg atttgaaaca cttttagcac tttcgccagt
    48721 tatttatgga gcaatcgtag gcttcttctg gcaaattctg gtgatgtttg gtctccattg
    48781 ggcaatcgta ccaatgggat tgatgcaatt ttctgtgaat ggttggcaaa atattatgac
    48841 acctgttgca gtagtgtctt ttggacaaac tgcagcactt accgcactct actttaagct
    48901 tagaaatcca aaagacaaag caattgcaat accagccatt gtttctggta ttgtggggat
    48961 tacagagcca gctatttatg ggtttacatt accacgtaaa aaaatattta tttttacctg
    49021 tgtcggtggt gcgttagggg gcgcgtatag tgggttaatg aatttaactt cttggaatca
    49081 aggtggacta ggcatcttta caattcccaa ctatattaga ccagatggtg atttaacaga
    49141 tgtgattaat gtattgattg ggatcgccat tgcgatggtg gtatccttta cgctgacttt
    49201 tttcttttgg aaggatgaag caggtgaaac agatgatata cagaaaaaat caggtaaaga
    49261 aattgtaaaa acaccgatac aaggacaaat cgctccacta aatgcagcaa aggatgcagc
    49321 ttttgcacaa ggaacactag gtcgaggaat cttgatctac cctgaaaaag gagaagtacg
    49381 tgcccctttt gacggaacag tcatgaccct gttcccgacg aaacaggcaa ttggaatggt
    49441 ttctgaaaca gggctggaat tgctgattca tgtcggattg gatactgtgc agttggaagg
    49501 gaaatatttt gaaagcttag tgcagcaagg ataaagagtg aaacaaggcg atctgttgct
    49561 acgcttcgac aaaaagaaaa tcgaaaagga aggatacagt ttagaaacac ctgtgatcgt
    49621 caccaattac acggattatt tggatatttt ggaaaaccaa ggggagacgg tcgggccaga
    49681 cgatgcactt atcaccgcac tgacctgaac ggttaggtga agaatggact aggcttaact
    49741 attcttttta ttccacttct ttattttcaa aattgaaagg ctctttcatg atggctgagc
    49801 tgatagggcg tttatcgaat ttttgaccga cagaaattag atggactaaa ttctgttgat
    49861 aattttctgc aaaaacacaa ctatataaca cgtctagaag ataacaaatt gatgtattga
    49921 tcgtaaaatt accaattttt gaatacagtc gctcgcgtgt cgtaagtcgc aaagcggctg
    49981 tactcattgc agatagcgtt gaatcaccga tactggtcaa agctaaaatt ggaacatgat
    50041 tttgtttcaa tatttctgcg gtacgaagga tcacattgtt ttcacccgta taagaaatca
    50101 gaatcccgca catatcactc gtgcaattgt acgcttcata gaatgattca ccaaaagtgg
    50161 tgacaatcgt gacatccatt ttgatgcgct tcattttcag catgaaatct tgagaaatca
    50221 aagtattcga gttactggcg aaaatcacga ttttttttgc ttgaagcatt agttgtttgg
    50281 ctttttgcag ttggtcatga tgaatgagag aaagtgtatc atgaatcgtc atctgttcta
    50341 aagaagccat tttatttgcg atcgtcataa taccgtctgt ggtggaaaaa ggaagattcg
    50401 catctacgtc ttgaaaattc ccttcaagat aggctgtttc agctaaaaaa gcattacgaa
    50461 aactgaccca gccatcaaaa cccatttttt ttgctacacg gatgagtgta gaggggtgga
    50521 cataacatcg ctcagcaatc gcttggatgg tcatttcgcc aagtgctgga gaatcgctta
    50581 agagaaactg gatcacttca ttttctgaag gagaaaagga gatttctttg attttttcac
    50641 gtaataacat gtagatacct tcttcttatt tttttacgta aattataact tttttgaaaa
    50701 tgatttgtaa acggatttat actatataac ttaaaataga cattttttga caagatattt
    50761 acaaaaatcc actagaaaac agtaaatttt gtaaatgtta ctggaaagaa acagatttct
    50821 attgtttgtt ttgtttacaa aaaagataat gaaagtgtaa aaaagtaaag gagtgagaac
    50881 atggcaaaag gaatcaaaat cgctacgatt ggtggaggca gcagttacac ccccgagttg
    50941 atggaaggat ttatcaaaag atatgaggaa ttaccgatac gagaaatctg gctcgtagat
    51001 gtagaagaag gaaaagaaaa gcttgagatc gttagtcaga tgtctcagcg tatgtgggat
    51061 gcttctccgt atgaagtcaa gatctatgca actctggatc gggaagaagc attgaaagat
    51121 gcggattttg ttacgactca gtttcgtgtc ggtcaattag atgcacgaat caaagacgag
    51181 cggatcccta gttattatgg gatgattggg caagaaacaa atggtgctgg cgggatattc
    51241 aaagcttttc gtaccgttcc agtcgttttg gcaatcgttg aggacatgaa gcgtttatgt
    51301 ccaaatgctt ggctgatcaa tttcgcgaac ccaagtggga tggtgacaga agcagttatc
    51361 agatatggca aatgggataa agtgattgga ttatgcaatg tgccagtgat ggcgatgatg
    51421 acagaaccag caatgcttgg caagaaaaaa gaagagctga tctacaagtt tgccggtcta
    51481 aatcatttcc attggcacaa agtagcagat aataaaggaa atgaccgcac ggcagaattg
    51541 attgatcgtt tatacgatga agagaatgga ttaccgaaaa atatctttga tatcccgttt
    51601 ttcaaagaac aattaaaaca aatgaacatg atcccttgtg gctaccaccg ctattactat
    51661 cgtgaagaag aaatgctgga acatgcttta gaagaatatc aaacgattgg tacaagagcg
    51721 cagcaagtga aagaaacaga agcagagcta tttgaattat acaaagatcc agaattagac
    51781 cataaacctg aacaattgca aaaacgaggt ggcgcttatt attcagacgc tgcctgtgaa
    51841 acgattgctt caatctatgg aaataaagaa acacagatcg tggtatctac aaagaatgat
    51901 ggagctgttc ctgacctgcc ggcagattgt gtagtagaag tcactgccta tgttggcgca
    51961 caaggagcga gaaatgtagc gtttggttct cttcctgctg ctgaaagagg ctggttgcaa
    52021 gtaatgaaga atatggaatt gctgacgatc gaagcagctg tgactggtga ttatgggaca
    52081 gctttacagg cgtttacgat caatccactt atacgatcag gaaagacagc aaaacggatc
    52141 atggatgagt tgtttattgc acaccagcag tatttaccgc aattcaagga gacaatcagc
    52201 cgattaaaag aagaaggaat cgaagttcaa gatgaactgg caagagaatt atcaggtaat
    52261 acacatataa tggaggaagt ataatgggat tcagaaaaga ttttttatgg ggcggtgcta
    52321 cagcagccaa tcaatgtgag ggcggttatg atgaaggtgg acgcggacta gcaaacgtag
    52381 atgttgtgcc aatcggaaaa gaccgttttc ctgttatcac cggaaagaaa aaaatgtttg
    52441 aatttgatga ggatcatttt tatccagcaa aaattgcaat cgatatgtat catcgttata
    52501 aagaagatat tgctttgttt gcagaaatgg ggttcaagac ttatcgaatg tccatcgcct
    52561 ggagtcgtat ttttccaatg ggggatgaga aagagccgaa tgaagctggc ttgaaatttt
    52621 atgaggatgc ctttaaagaa tgccaaaagc acggaattga gccacttgtg acgattacgc
    52681 attttgattg tccaatgcat ttgatcaaag aatatggtgc gtggcgttcc agagaactcg
    52741 ttggttttta tgaaaatctg tgtcgagtca tcttcaatcg ctataaagga cttgtcaaat
    52801 attggctgac attcaatgag atcaatatga tccttcatgc accattcatg ggcgcagggc
    52861 tgtattttga aaaaggagaa aatgaagaac aaatcaaata tcaagcggca catcatgagt
    52921 tggttgcaag tgccatcgca acgaagattg ctcatgaagt agatccggag aacaaagtag
    52981 gctgtatgct ggcagcagga gcatattatc catacacttg caatcctgaa gatgtttggg
    53041 cttctagaaa atcagatcga gaaaattatt tcttcattga tgtccagtca cgaggagaat
    53101 atcccgctta tgcattgaaa gaaatggagc gaaatggcat tcagatcgaa atggaaccag
    53161 gggatgccgc attgctgaaa gaacatactg ttgattttat ctctttttct tattatgctt
    53221 cccgagtttc gactaccgac aacgaactct tggaacagac tgcaggaaat atctttgctt
    53281 ctgtcaaaaa tccatatctg caagcaagtg aatgggggtg gcaaattgat ccattaggct
    53341 tgagaataac gatgaatgat atttatgatc gttatcaaaa accattgttt attgtagaaa
    53401 acggcttagg tgcagtcgat acgccagatg aaaatggtta tgtggaagat gattaccgaa
    53461 tcgattacct ggcagcgcat atccaggcga tgaaggatgc agtagaacta gacggagtcg
    53521 atctattagg ctatacgact tggggatgta ttgatttagt atcagctggt accggtgaga
    53581 tgaagaaaag gtacggattc atttatgtcg atcgtgataa ccaaggaaat ggcacattag
    53641 cccgttcaaa gaaaaaatca ttcaactggt ataaaaaagt aattgattca aatggagaaa
    53701 atctttcgaa cgattgatca atgatttata aaagtctatt gtttttcagc ggatttttcg
    53761 agtataataa agctattcga gaaacgcaag cagaacaata gacttttttt cgcattggct
    53821 gtaaagtatg cttacttgat taagtaaagg agaatctaca tatgtatgat gtaatcgtta
    53881 ttggcgcagg tcctgctggg atgactgctg ctttatatgc ttcacgttca aacttatccg
    53941 tattgatgat cgaacaaggt gcccctggcg gccaaatgaa caatacggca gaaatcgaaa
    54001 attatcctgg attcgattcg atcatgggcc ccgatctagc ttataagatg tatgaaagtg
    54061 tctcaagatt tgggacagaa aatgcttatg gaatcgttca agatatcaag gatcacggca
    54121 gccataaaga agtcatctgt gaagataaaa gttacgaagg aaaaacagtc attatcgcaa
    54181 caggatgtat ccaccgtaaa ttaggcgtac ctggcgagga agaatttgct ggacgaggcg
    54241 tttcttactg tgcagtctgt gatggtgcgt ttttccgtaa caaacgtcta gtagtcatcg
    54301 ggggtgggga ctcagcagta gaagaagcca tctatttgac acaatttgct tctgaagtag
    54361 tgatcgtcca ccgtagagat gaattacgtg cacaaaagat catccaagac cgtgcatttg
    54421 caaatgaaaa aatttccttt atgtgggata cagtcgttga cgaaatcgtt ggaaacgaaa
    54481 tggtagtgac aggtgtgaaa gcacgtaatg tcaaaaccgg caatgaattt gatttagcag
    54541 cagacggagt attcatctat gttggactgg atccattaac tgcacctttt agagaagcag
    54601 gtttgacgaa cgaagctggc tggattccaa cagacaacga aatgaaaacg aatatgccag
    54661 gcgtttttgc catcggagat gttcgtgaaa aagatttgcg acaaatcact acagctgttg
    54721 gtgacggcgg tattgctgga caacaagtgt ataaatactt ggagtcttta gaagaaacaa
    54781 cagcataagt ttaaaaagag tagaagaacg ggttcaattg ttcttttact cttttttttc
    54841 gcgtgaaatt tactgaatct gatttatgcg aacacgtcca acaccttttg ataaaagaat
    54901 cctttcttga tttaagcgtt ttttggtcct catactttca tatctaataa gtgaatgcta
    54961 tacttattaa gaaccatatt tcagaaagag gtgttatttt catgtcttgg gaacaagtgt
    55021 atgaacaatg ggtacatgaa gaaaatttag aagaaaactt aaaaaaacaa ttaaatgatc
    55081 tgggtgaaga tcctgaaaaa cttgaagatg ctttttatgc accgttggaa ttcggtactg
    55141 caggtatgcg gggaatctta ggacctggga tcaatcgaat gaacatctat acggtaagac
    55201 aagcaacaga aggactagca cgtttcatgg atacacaagg tgaagaaaca aaacgccgag
    55261 gtgtcgctat cgcttatgac tcacgccatc agtcaccaga atttgcaatg gaagcagcca
    55321 aaacactagc acatcacaat atcccgtctt atgtattcga aagtctgcgt ccaacaccag
    55381 agctttcttt tgcagttcgt catttgaaga cgtttgcggg aatcatggta accgcatctc
    55441 acaacccagc ggcttacaat ggatataaag tctacggaga agatggcgga caaatgcctc
    55501 ctgcagacgc agatgcattg acgaaatatg tccgtgaagt cagcaatccg ctaaaagtcg
    55561 aagtattatc tgacgaagaa gctaaacata gcgggttgat cacgatcatc ggagaagaag
    55621 tggacgctgc ttatctagaa gaaatcaaag cagtgacgat tgatcgtgaa ttggttgaaa
    55681 caatggggaa agatttgaaa cttgtgtaca cgccacttca tggaacaggg aaaatgttgg
    55741 gcgaacgtgc gttgaaacaa gctggattcg aacaattcgt actagttccc gaacaagctg
    55801 tggcagatcc agatttcact acggtcaaat cgccaaatcc agaagaacat tcagcttttg
    55861 aatatgctat acgacttgga gaaaaagaag gagctgactt gctgattgca acagatcctg
    55921 atgcagaccg tttaggcgca gcggttcgtt tgccagatgg ttcttatgaa gtattgactg
    55981 ggaaccaaat cggagcattg tttgctcaat atattttgga agcacatcaa tcaagaggca
    56041 ctttaccaga aaacgcagcg gtattgaaat caatcgtttc cagcgaattg cctacagcaa
    56101 ttgcggaaca ctacggtgct accatgttca atgtgttgac agggtttaaa ttcattgctg
    56161 aaaaaatcca acaatttgaa gaagaccatt cacatacttt tatgtttgga ttcgaagaaa
    56221 gttatggtta tttagttaaa ccttttgttc gcgataaaga cgcgatccaa gcattgcttt
    56281 tattagcaga agtagcagct tactataaaa aacaaggcaa aacgttgtat gacggcttgc
    56341 aaacgatttt tgaaacctat ggctatttcg cagaaaaaac gatttctgtg acaatgagcg
    56401 gacaagaagg ttctgcgaaa atctctgctt tgatggaaaa attccgtaaa gaagcaccga
    56461 cagaatttgc cggagcaaaa gttattcaaa cagaagactt taaagaattg acgagaacag
    56521 accgtgaagg aaacgtagaa aaactaacaa caccgccatc cgacgtattg aagtatacat
    56581 tggaagaaaa tggctggatc gctatccgcc cttcaggaac tgagccgaaa atcaagtttt
    56641 atattggtgt aaaaggaagc tctacagaag acgcagccga aaaagtagcc tcttatgaag
    56701 cgattatcaa aaagatgaca gaagaataaa aaacttgaga ctgatggaaa aagtggtaaa
    56761 ctttagaagt cagtcttttt tcaagttgga ggtgaatgga ttgccagaca cgcaaaaatc
    56821 aaaagtagag aaagtcagtc aattattcaa aatgttgagt gatcccactc gtcttaaaat
    56881 tctgctatat ctgaaagacg gggaacaaaa tgtgacagca atcacccaag cagtggaaat
    56941 ggagcagtct gctgtatcgc atcaactacg tttattaaga gaaaatcatg tcgtcaagtc
    57001 tcatcgcgag ggaaaagcga ttttgtatag tcttgatgat tctcatgtac tggatatttt
    57061 gaaccagaca ctcaaacatg tggaacatca ataacgatag gtgaaaatag ataaacactg
    57121 gagtgtgaca acgaagaaat ttcgttgtca cactccagtg ttttttaaga aaaagacaaa
    57181 aatgattaat cgcttttttc tgttgtttca gttccataat aactatgatc ttctaggtct
    57241 aaagcattca aaataagcga agccgtttct tcaatagata aagatgccac attgatcact
    57301 acacatccta gtttttcata aagatcattc gcaaaatcga gttcagctct aattttttcg
    57361 atatcggaat aagcagtatc agggtttaat ccgtaagagc gcatccgttc tttacggata
    57421 ttatttaaaa tatctgggtt attcgttagt cccacgattt ttttaggatc gatttcccac
    57481 agctgtttgg gaatatgtgc ttggggaatc aaaggtaaat tagcaacttt taaattttta
    57541 tttgctaaaa acaagctcaa aggcgttttg gaagttcggg atacgcctag caaaacgaca
    57601 tctgcttcta aaaaaccacg aggatctttc ccatcatcgt attttacagc aaattccatt
    57661 gctttgatcc gtttgaaata gttctcattc aataaatgga gggcaccagg ttgccgaatt
    57721 ggcttgatac cagttaaacg ttcaatttct gatatcggtg gcgtcatcac atcgaaacta
    57781 aataattgat gttcttcaca aaaagaacgt gttatctcga tcagttcttg attgattaat
    57841 gtatgcagga caagtgcttt ttcttctaat gcatcttgca atgcctgcct taatgttttt
    57901 tcatctgtca cgaacgttct gcggaatagg ttgaactcaa cggtaggata ctgagccata
    57961 gtagcttgcg ctagttttgt cgcagtttct ccagcagagt cggagatgac aaaaaaagta
    58021 acgatttctg tagaatcgga agacatggat aaaacctcac ttgcattttt tttatgttta
    58081 ttataccata ctctagaatg cgtacttcgt aatcattttg atttggagga ataagtcatg
    58141 aaaaaacaga cattgatcga acaatcatta gaaacattga aaaataacgg ttttaaatat
    58201 actaaaaaaa gagaagcatt gttaacttat ttagtgaagc gtaaccgcta cgtatctgct
    58261 aaagaagttt ttgactatat gaatcaggaa ttcaaagggg taagttatga tacgatttac
    58321 cggaatctcc atgattttgc agagatcgat ttactggaag aaaccgattt aaatggtgaa
    58381 atgaagtttc gttttcattg ctgtcagggg gaaatcggcc atcaccatca ttttatctgt
    58441 acagtgtgcg gaacaacgaa agaaatccat atgtgtccaa tgaattattt cgaagaacag
    58501 ctaggtggat gcacgatcga agggcataga ttcgagattt tcggaagatg tgaaaattgt
    58561 caataaggat ttaaataaaa taacatttga taatttaaaa aaaaagcaag atttccttga
    58621 cggtcaaaac agcattagat ataatattta caggacagtc ttgttttttg agatatattt
    58681 caataacaat tacggttact ttttaagctc ggagggaggg aattaacatg tcaaaaacag
    58741 tcgttcgcaa aaacgaatca cttgacgatg ctcttcgtcg cttcaaacgt tccgtgtcaa
    58801 aagcgggtac tttacaagaa tctcgtaaac gtgaattcta cgaaaaacca agtgtaagac
    58861 gcaagaaaaa atctgaagca gctagaaaac gcaaaaaatt ctagttctgt gatgaattgg
    58921 agttggtagt gtgtcactac taagtagatt aaacgatgac atgaaagcag cgatgaaagc
    58981 gaaagataag gaatctttac aagtcatccg aatgatcaag tcatctatac aaaacgagca
    59041 gattaaagaa ggtcacgact tgacagaaga agaagaacta acggtgttgt ctcgcgaaat
    59101 gaaacagcga cgtgattctt tgcatgagtt tgaagaagca ggacgtgacg atttagctga
    59161 aaaagtaaaa agtgaaattg taatagtcga aaaatatatg ccggaacaac tttccgacga
    59221 agaaattcga caacttgttc aagaagcaat cactcaaact ggtgcttcat caatgaaaga
    59281 atttggcaaa gttatgggtg caattatgcc taaagtcaaa ggaaaagcag atggaaacca
    59341 agtgaatgcg attgtgaaag aactattaca atcttaattt tatcatttaa actgcggaca
    59401 gtg
//
LOCUS       DAFTHM010000007        51720 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFTHM010000007 DAFTHM010000000
VERSION     DAFTHM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.007"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(261..956)
                     /locus_tag="L7C88_000463"
     CDS             complement(261..956)
                     /locus_tag="L7C88_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBP9557321.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(1046..2146)
                     /gene="ychF"
                     /locus_tag="L7C88_000464"
     CDS             complement(1046..2146)
                     /gene="ychF"
                     /locus_tag="L7C88_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBP9557322.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(2155..2346)
                     /locus_tag="L7C88_000465"
     CDS             complement(2155..2346)
                     /locus_tag="L7C88_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBP9557323.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(2367..3257)
                     /locus_tag="L7C88_000466"
     CDS             complement(2367..3257)
                     /locus_tag="L7C88_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBP9557324.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(3244..4011)
                     /locus_tag="L7C88_000467"
     CDS             complement(3244..4011)
                     /locus_tag="L7C88_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBP9557325.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(4023..4736)
                     /gene="rsmG"
                     /locus_tag="L7C88_000468"
     CDS             complement(4023..4736)
                     /gene="rsmG"
                     /locus_tag="L7C88_000468"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBP9557326.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(4968..6869)
                     /gene="mnmG"
                     /locus_tag="L7C88_000469"
     CDS             complement(4968..6869)
                     /gene="mnmG"
                     /locus_tag="L7C88_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBP9557327.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(6886..8283)
                     /gene="mnmE"
                     /locus_tag="L7C88_000470"
     CDS             complement(6886..8283)
                     /gene="mnmE"
                     /locus_tag="L7C88_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBP9557328.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            8582..8965
                     /locus_tag="L7C88_000471"
     CDS             8582..8965
                     /locus_tag="L7C88_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557329.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(9133..9891)
                     /locus_tag="L7C88_000472"
     CDS             complement(9133..9891)
                     /locus_tag="L7C88_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBP9557330.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(9909..10727)
                     /locus_tag="L7C88_000473"
     CDS             complement(9909..10727)
                     /locus_tag="L7C88_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBP9557331.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(10724..11080)
                     /gene="rnpA"
                     /locus_tag="L7C88_000474"
     CDS             complement(10724..11080)
                     /gene="rnpA"
                     /locus_tag="L7C88_000474"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBP9557332.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(11198..11332)
                     /gene="rpmH"
                     /locus_tag="L7C88_000475"
     CDS             complement(11198..11332)
                     /gene="rpmH"
                     /locus_tag="L7C88_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBP9557333.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            11855..13189
                     /gene="dnaA"
                     /locus_tag="L7C88_000476"
     CDS             11855..13189
                     /gene="dnaA"
                     /locus_tag="L7C88_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBP9557334.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            13387..14517
                     /gene="dnaN"
                     /locus_tag="L7C88_000477"
     CDS             13387..14517
                     /gene="dnaN"
                     /locus_tag="L7C88_000477"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBP9557335.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            14746..14988
                     /gene="yaaA"
                     /locus_tag="L7C88_000478"
     CDS             14746..14988
                     /gene="yaaA"
                     /locus_tag="L7C88_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBP9557336.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            14975..16099
                     /gene="recF"
                     /locus_tag="L7C88_000479"
     CDS             14975..16099
                     /gene="recF"
                     /locus_tag="L7C88_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBP9557337.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            16096..18042
                     /gene="gyrB"
                     /locus_tag="L7C88_000480"
     CDS             16096..18042
                     /gene="gyrB"
                     /locus_tag="L7C88_000480"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBP9557338.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            18062..20533
                     /gene="gyrA"
                     /locus_tag="L7C88_000481"
     CDS             18062..20533
                     /gene="gyrA"
                     /locus_tag="L7C88_000481"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBP9557339.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            20769..21068
                     /locus_tag="L7C88_000482"
     CDS             20769..21068
                     /locus_tag="L7C88_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBP9557340.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            21118..21630
                     /gene="ssb"
                     /locus_tag="L7C88_000483"
     CDS             21118..21630
                     /gene="ssb"
                     /locus_tag="L7C88_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBP9557341.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            21656..21892
                     /locus_tag="L7C88_000484"
     CDS             21656..21892
                     /locus_tag="L7C88_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBP9557342.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            22035..24010
                     /locus_tag="L7C88_000485"
                     /pseudo
     CDS             22035..24010
                     /locus_tag="L7C88_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
     gene            24016..24468
                     /gene="rplI"
                     /locus_tag="L7C88_000486"
     CDS             24016..24468
                     /gene="rplI"
                     /locus_tag="L7C88_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBP9557343.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            24742..26109
                     /gene="dnaB"
                     /locus_tag="L7C88_000487"
     CDS             24742..26109
                     /gene="dnaB"
                     /locus_tag="L7C88_000487"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBP9557344.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            26889..28181
                     /locus_tag="L7C88_000488"
     CDS             26889..28181
                     /locus_tag="L7C88_000488"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBP9557345.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            28917..29780
                     /locus_tag="L7C88_000489"
     CDS             28917..29780
                     /locus_tag="L7C88_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBP9557346.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(29909..31531)
                     /locus_tag="L7C88_000490"
     CDS             complement(29909..31531)
                     /locus_tag="L7C88_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9557347.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            31780..32301
                     /locus_tag="L7C88_000491"
     CDS             31780..32301
                     /locus_tag="L7C88_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBP9557348.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(32487..34217)
                     /gene="spxB"
                     /locus_tag="L7C88_000492"
     CDS             complement(32487..34217)
                     /gene="spxB"
                     /locus_tag="L7C88_000492"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBP9557349.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            34382..35200
                     /locus_tag="L7C88_000493"
     CDS             34382..35200
                     /locus_tag="L7C88_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBP9557350.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(35303..35500)
                     /locus_tag="L7C88_000494"
     CDS             complement(35303..35500)
                     /locus_tag="L7C88_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557351.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            35669..36247
                     /locus_tag="L7C88_000495"
     CDS             35669..36247
                     /locus_tag="L7C88_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBP9557352.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            36342..36479
                     /locus_tag="L7C88_000496"
     CDS             36342..36479
                     /locus_tag="L7C88_000496"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557353.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(37292..37795)
                     /locus_tag="L7C88_000497"
     CDS             complement(37292..37795)
                     /locus_tag="L7C88_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBP9557354.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            38154..39179
                     /locus_tag="L7C88_000498"
     CDS             38154..39179
                     /locus_tag="L7C88_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBP9557355.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            39502..40380
                     /locus_tag="L7C88_000499"
     CDS             39502..40380
                     /locus_tag="L7C88_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBP9557356.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            40856..40972
                     /locus_tag="L7C88_000500"
     CDS             40856..40972
                     /locus_tag="L7C88_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBP9557357.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            41900..42238
                     /locus_tag="L7C88_000501"
     CDS             41900..42238
                     /locus_tag="L7C88_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557358.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            42332..42562
                     /locus_tag="L7C88_000502"
     CDS             42332..42562
                     /locus_tag="L7C88_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557359.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            42962..43333
                     /locus_tag="L7C88_000503"
     CDS             42962..43333
                     /locus_tag="L7C88_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBP9557360.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(43607..44299)
                     /locus_tag="L7C88_000504"
     CDS             complement(43607..44299)
                     /locus_tag="L7C88_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBP9557361.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(44302..45087)
                     /locus_tag="L7C88_000505"
     CDS             complement(44302..45087)
                     /locus_tag="L7C88_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBP9557362.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            45324..46724
                     /gene="lacG"
                     /locus_tag="L7C88_000506"
     CDS             45324..46724
                     /gene="lacG"
                     /locus_tag="L7C88_000506"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBP9557363.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            46749..47066
                     /locus_tag="L7C88_000507"
     CDS             46749..47066
                     /locus_tag="L7C88_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBP9557364.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            47079..48752
                     /locus_tag="L7C88_000508"
     CDS             47079..48752
                     /locus_tag="L7C88_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBP9557365.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            48766..50397
                     /locus_tag="L7C88_000509"
     CDS             48766..50397
                     /locus_tag="L7C88_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBP9557366.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            51269..>51720
                     /locus_tag="L7C88_000510"
     CDS             51269..>51720
                     /locus_tag="L7C88_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9557367.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGR"
BASE COUNT        15940 a         9509 c        10339 g        15932 t
ORIGIN      
        1 gaacaccgtt tagtggagag gctgtgaaaa agctgcttag tttcgagtag taagaaaaat
       61 tttgtgaaaa tggctttcca catttttgca taaattggac ttaataccga gaaactggct
      121 tttgaacacc gtttatcgta aaaagggact gtgacaagac ttttgtcaca gtcccttact
      181 attatttaac tatggataaa caaaatgagg ttctttacta cccctagata tctagcaaaa
      241 tagctgatct ttttgctagt ttatcttctt gggacggata aacttccaat aatcccgtat
      301 tttttcttca agtagtaacg gattgctaaa gcagttgccc cgataatgat aactactact
      361 ggatctaata ctggattgat aactggtggc aatagtgttg tcgcagaaaa cagtacgacc
      421 caaagaagtg tcgttccacc taggataagc aatgtcttac ccattcctgg tttcttgctt
      481 cgatctgctc cgggatattc atattgatag atgtatttgt acatcatata aaagacccag
      541 ccaccgattg cagaacctag aacgagtgta gaaaagccat aagctggcgt tgttccacgt
      601 gaaaacaatc cggtaatcgc aatcatgata cttaatagac caagcaacag caacgtatta
      661 tctaaccaca tcaataaagg ggtggatgaa ttttttactt ctgctggctt attgatgatt
      721 gcttccgttc tttcagagac tgtcccaaac aattgacggg ctgttcttcc gcctttttgt
      781 tctgcaacta aagtaggcag aatgtcatga agggctttta ctttttcttc ttcagacaaa
      841 ttcgctgctt ctaaagattt tttcaaatca aaaatgtact gttgatttct tttggttaat
      901 tttgtttcta aactattgtt ttcttttacg attgctcgta attgttctgg ttccattatc
      961 taatagtcct ccttagccgt tccttttctc aacggtcgtc acaaaagaca ttctaccata
     1021 ttctacagct agtttgatag cccttttaca cattaaagcg gaataacatt acgtcgccgt
     1081 cttgtacgac ataatctttt ccttctaatc gaacacgtcc agcttctttt gctgcatgca
     1141 tgtttccgta atgatccaag tcttcaaaag agacagtttc tgcacggata aatccgcgtt
     1201 cgaaatctga atggatgatt cctgctgctt gtggtgcttt gattcctttt ttgaatgtcc
     1261 aagcacgtac ttcttgttcc ccagcagtaa agtaagtagc taagcctaac aaatcataag
     1321 cagcacggat caactgatcc aaacctgatt cttcgattcc taaagcttct aaaaattccg
     1381 ctttgtcttc ttcatctaat tctgcgattt cttcttctgc acgagcactg accacgatca
     1441 cttctgcatt ttcttctgca gcaaagttgc gcacttcttg tacataatga ttcgcgtctg
     1501 catctgctac gtcatcttct gagacattgg ctacataaag aattggtttt gtcgtcaata
     1561 aaaatagtga tttaacgatt ttttgttctt cttcagtaaa ttcgatcgtt cgggcagatt
     1621 ttccttcttc cagtacaggt ttgattttat ccagtacagc tagttctgcc actgcatctt
     1681 tatctttggt tttagcaact tttgctacac gagtatagcg tttgttgata gattctaagt
     1741 ctgctaacac tagttccaag ttgatcgtat caatatcttc tagtggatca acacgtcctt
     1801 ctacgtgagt aatattatca tcatcaaaac agcgaacaac gtgacaaata gcgtctactt
     1861 ggcggatatg gcttaagaat tgatttccca aaccttctcc tttacttgcg ccttttacga
     1921 ttccagcaat atctgtaaat tcaaaagtcg tcggaacagt ttttttcgga tgtacaagtt
     1981 ctgttaagcg ttgcaaacgc cagtcaggta cttctaccat ccctacgttg gggtcgatcg
     2041 tcgcaaaggg atagtttgct gcttctgctc ctgcttttgt gatcgcatta aacaaagttg
     2101 attttcctac gttgggcaac ccaacaattc cagcagtcaa tgccataaat ttattcactc
     2161 tttctctgca tttttttcaa ttactttttt taatttcttt tcaaaatctc gacgggtcat
     2221 catgacgata tgtccgcaat tcatacatct gattttgata tctgcgccca ttcgaatgac
     2281 ttcccagcga ttcgtctggc aagcgtgagg ttttttcatt tcaacgatat cgtgcaagtc
     2341 gtacataaaa atagcctcct ttttgtttat tcttcatcaa attgaatatt caagatatca
     2401 agaattcgag tcaaatcttt ttgagaaaga tattcaatct cgatcttacc tttcccattt
     2461 ttttcttgga tagctacact tgtaccaaat ttatccatca aacgatcttc gctttctcgg
     2521 atataatatg gtttttcctt tgctagcctt gggatttttt tcttttcttt tccatcattt
     2581 tgatttaact cagaaacaag ctgttccagt tggcggacag ttaaattttc agttactgca
     2641 cgattggcta atttcaagat caatgtttta ttttttaaac ctaacagcgt acgggcttgt
     2701 cccatagata aacgctgatc ttgtaccatt tccttgacaa gatccggtaa agaaagcaag
     2761 cgcaaataat tggcgatata aggtctgctc tttcctaaac gactagctac ttctgcttgt
     2821 gttagtttca ggtttttcat cagcatctca tatgcttctg cttcttctaa cggattcaga
     2881 tcttctcgct gcaagttttc cagcactgct acttgcatca tcgcttcttc gtcaaagtct
     2941 ctaacgatag cagggatcgt ttctttttca gctagtttgg acgctcgaaa acgtcgctcc
     3001 cctgcaataa tctcatatcc ttttactgcg gaacggcgta cgatgatggg ttgaaagaca
     3061 cctgattgtt caatagaatt agctagttcc tgcaaagata cttcttcaaa tgttttacgg
     3121 ggctgatacg gatttggtcg cagctcattc aatggtagct ggacaacggt atcatctttt
     3181 acatccaccg tctctaagtt ttctaaatct tgaaacagtg catcgattcc tcggcctaat
     3241 cctttacttt tcttcacgac ttaccacttc ctttgccaat gcttggtaga cttcagctcc
     3301 tcgagaacgt ggatcgtagt cgatgatcgg ttttccatga ctaggtgctt ctgataaacg
     3361 aatatttctt ggaatgatcg tttcgtaaac tttttcgcgg aagtatttac gtacttcttc
     3421 tacgacttca tttcccagat ttgttcgtgc atcatacatt gtcagtaaga ctccctcgat
     3481 ctctaattct ggattaaagt gtttttggac taaacgaacc gtattcagta attggcttaa
     3541 tccttccaat gcgtaatact cacactgaac aggtatcaaa atcgaatcac ttgctgtaaa
     3601 tgaattgatt gtcagatggc caagagaagg cgggcaatcg atcaaaatat aatcatactg
     3661 actgcttact tctgctaaag atccttttaa tcttgattct cttgccatca ttgacgtcaa
     3721 ttcgatctct gctcctgcta attggagagt cgcaggcaca atactcaaat tttcgtgttc
     3781 agtgatcaaa gttgcctcat caattggcaa ttcattgact agaacatcat agatgtctct
     3841 tgtcacatca ggttttctga tcccgacacc actggtagca tttccttgtg catccatatc
     3901 cactagcaat acttttttgc caaggctagc aagacaagca cctagattca ccgtcgtcgt
     3961 tgttttgccg acgccacctt tttggttcgc aacagatatt atttgtgcca tctcttctcc
     4021 tcctatttga ttggctgctt attaggcagt ccgggctttc ttgggtattt ctttggggtt
     4081 ggtttctttt tttgaataac gatgatatgc cgttgatcag agacattcgg caaggtaacc
     4141 gcctcttctt tgaggaattt accacctaat aaagcaatcg cttgttttgc ttctgtcaat
     4201 tcctcttcac tttttgctgc tttcaatgca taaaaatagc cttcttgttt agccaagggc
     4261 aaacacaatt ccgctaacac attcaaacga gcaaccgcac gagcagtgac aaggtcaaat
     4321 gatgcacgaa agtgaggatt ttgcccaaat gtttctgccc ggtcatgata taaggaagca
     4381 tcgattccta ataatcgggt taactcagat aagaaggtta ttcgtttatt cagagaatca
     4441 acgatcgtta tctgcagttc tggaaaggca atttttaaag gtatgctagg aaaccctgcc
     4501 cccgaaccaa catcgcataa agataaaggt tgcgtaaagt ctacttcaaa tgctaatgta
     4561 agtgaatcgt aaaaatgctt cagatatacg tctttttcat ccgtaatagc tgtaaggttc
     4621 atcttttcgt tccattcgac taatgtccga taataaatag cgaattgatt catttgatga
     4681 tcggtaagct ctatcccttt ttctgccaag gattggcgaa attcttctgg tatcataaat
     4741 attcctttca ttgtgaaaca gcaattgttt cacagattct ctccctactt taacgcaaaa
     4801 tctctagaca tgcaatcctt ccatatggat tcttaaaaat ttgaaaagta agaaaagccg
     4861 atagactttt tctttctagt atgactcata aaatatacac agaagagaga actagctttg
     4921 agcaatttct gcaaaaacta gttctctctt ctatttatta ttacgtatta cgctggttca
     4981 ctgactttcg caatcttccc ttgttcgata tagaccatta ggatacttag gtctgcaggg
     5041 tttacgccac tgattcggct agcttgggca attgtttctg gttggatttt ctgcaatttt
     5101 tgttttgctt ctgttgctaa tccgttgatt gctgcgtagt cgatgttttc tggaatcttt
     5161 ttcgcttcca tgcgttttaa tttttctact ttttccatgg cttttttgat gtagccttca
     5221 tatttgattt ggatttctac ttgttcgatt tcttttcgtg tcaattcttc attttctgga
     5281 ataaaccgta gaagttctgc ataagtaatc tcaggacgtc ttaaaaagtc gcttgctagt
     5341 acaccatctt ttaatggtgc cgcattaatc gttgctaaaa agtcttggac ttcttctgtt
     5401 ggtttgattc gtacattcat caaacgtttg atttcttgtt caactgcttc ttttttcttc
     5461 aaataattct tgtattgatc ttcttttact aagcctacac ggtgacccat ttctgttaat
     5521 cgcaaatctg cattatcatg acgtaaaagc agacggtatt cagcacgtga agtcagcaaa
     5581 cgataaggtt cgttcgttcc ttttgttacc aaatcatcga tcatgacacc gatgtaaccg
     5641 tcacttcgtt tgatcactaa aggttctttt ccctgaactt tcaaagctgc attgataccg
     5701 gcaatcagcc cttgtccagc cgcttcttca taaccgcttg taccatttgt ttgtccagct
     5761 gtataaagat tttcaacgac tttagtttct aatgtcggac ggagctggtg tggctctact
     5821 acgtcatatt cgatagcata tcctgtacgc atcatttcta ctttttctaa tccagcaata
     5881 gaatgaagca tgttgacttg aacatcctct ggtaaagaag tagataaacc ttgaacatag
     5941 acttcttccg tatttaagcc ttctggttcc aaaaataatt gatgacgtgg tttgtctgca
     6001 aaacgcacga tcttatcttc gatggatgga caatagcgag cgcctacccc ttcaacgatc
     6061 cctgtaaaca ttggggcacg atgtaagttg tctcgaataa tttggtgagt cgtctcacct
     6121 gtataggtca gccagcaaga ttcctgatct agtttatagg cactatctgg tgtgctgaag
     6181 ctaaaatgat tcggctcttt gtcaccaggc tgctcttctg taacagaata gtcgatcgta
     6241 cttgatttta ctcgaggcgg tgttcctgtt ttgaaccgtt cgatagcaaa gccaagttct
     6301 tttagatgat tcgctagtcc aatagaaggt tgagagttat tcggacctga tgaatatttc
     6361 aattcaccga taatgatttc tccgcgaagt gctgttccgg ctgtaataac aactgctttg
     6421 gcccggtagc tcgctcctgt ggacgtcact actccatgac aaacaccatc ttcgacgatc
     6481 agttcttcga cgattccttg tcttagcgtc aaatttggtt ctttttcgat cgtatgtttc
     6541 atttctgttg aataagcatg tttgtctgct tgtgctcgca atgctcggac agctgggcct
     6601 tttcctgtgt tcaacatacg catttggata taggttttat cgatattctt acccatttct
     6661 ccgcctaacg catcgatttc tcgaacgaca acgcctttag ctggtccgcc tacagaagga
     6721 ttacatggca tgaatgctac catgtccaaa tttattgtca gtaataatgt ttttgatccc
     6781 atacgtgcag cagcaagtgc agcttctgaa ccggcgtgtc ctgcgccaac aacgatcacg
     6841 tcatacgcat ctgcttcata atgttccaat cgtttgttcc tccttttatt ttcctaaaca
     6901 aaattgactg aataattgag tgattagctc atcttgtaca ctgtcgccga caacttctcc
     6961 tagatagtcc cagcaacgcg tcatatctat ttgaacgaga tccacaggca ttcctgaatc
     7021 aatacctgca atgacttctt caagtgagag ggaagctttt tctaacaacg cgatatggcg
     7081 ggtattagaa acataagtag cgtctctttc tcctgtttct ccgctgaaga ataaatcaga
     7141 aatagctgat tccaaacgat ctagtccgtc gtttttagct acggaaattg aaaaaactgg
     7201 ttcattttcg atcaatttct tcaatttttc ttgttccagc tgtgctggca aatctgtttt
     7261 atttagaaga atgatccgtt tcaatccact tgtcgcttcc aataattgtt catcttctgc
     7321 tgtcagtggt tcgctttggt ttagaacaag taagatcaag tctgcttctg ctaatgcttt
     7381 tcggcttctt tcgaccccga tccgttccac cacatcttct gtttcccgaa ttccagctgt
     7441 atcgattagc ttgagcggta ccccccgaac attgacatac tcttcgatta catctcgagt
     7501 cgttcctgca atatccgtaa cgattgcttt ttcttctctt aacaaatggt ttaacaaact
     7561 tgatttgccg acatttggcc ggccgatgat tgccgtactt aacccttccc gcagaacctt
     7621 cccttgcttg gatgtagcaa gtagcgcttg gattctttgt tggatcatct gcgctttttc
     7681 aagcaataac ttcgtagtca attcttcgac atcatcatat tctggataat caatatttac
     7741 ttctacttgt gctaatgtct ctaaaatctc ttgtctcaat gagcggatca aagcagacag
     7801 attgccgtct aactgattaa gagctagtcc cattgctttg tctgtttttg cccgaatcaa
     7861 atccatcaca gcttctgcct gtgaaaggtc aacacgacca ttcaagaatg ctcgttttgt
     7921 gaattcgcct ggctcagcta atcttgcacc ttctcttaac aatagctgca aaatttgatt
     7981 gactacaacg atcccaccgt gacaattgat ttctactaca tcttcccgcg taaatgtctt
     8041 tggtgctctc atcacggaga ccatgacttc atcgacaagc tgattgctct tgggatcaac
     8101 gatatgtcca taatggatcg tatgacttgg tacttctgat aatcgtttgt ttccagattg
     8161 ataaacttta tctgctagtt gcacagcttg atcgccactt aaacgaacga tactgattgc
     8221 accttctcca ggtggggtag aaattgccgc aatcgtatca aattctaaag taatttcagc
     8281 cattttttca cttccttttt cattttgcgc acaaaaaaag tgcccactcc accctttatg
     8341 cacaataaac ggtgaacttc gcactttgac tgcttgttct tgattaaatt ctggtcatag
     8401 attatcacac ttgctataag gaatcaagtg tttaaaacaa ttagatgaag ttgagcctgt
     8461 tctgcttcca ttaccttata tttaattgtc cttggatgtc tctttgcgtt ctttggttta
     8521 ttcgaagaga agatactgta taaacaaggc tttatctttc ttaaaaaaaa cggtacacta
     8581 aatggtagcg ctatctaaac tatacacttt tgaaaggaga aaatatgtga gcccgttcag
     8641 atctgctgca ttggaagaag aaagtgaccc tcggatcaac gatgtcgttt tatctacagg
     8701 gaatatcaac cagaaatata tcgtccgcga tatcgttttt gttgtggaat gcttagaagc
     8761 tgatttgttt gacccatctt ttcccaaaga tgaccttttc ttaacaacga agaggaaatt
     8821 aaagacgaag gtacttgaat atggtgcgaa tgcagtaatc aactgtcatt ttgagtatca
     8881 gcaaaaaaaa cgcgacggaa agtattttct ggaacttttt gcttatggaa cagtgatcca
     8941 atttatccaa acaacgattg gttaaatgaa acagacaaaa aaagcggatc aaaactgaag
     9001 acagtttcga tccgcttttt tctatcaaag ttagtgacta cttcatcgta tactctgata
     9061 agaatgattt ctagtaaaat atacttggtt tgaaaaactt tgtcaacgtg atttattcaa
     9121 aaagtaatgg aatcaataat attttttagc aggttctact actaaataac gataaggttc
     9181 ctcaccttcc gaatgtgttt ttacatgttc atctttgctt aatgcagcat ggatttgttt
     9241 acgttcaaat gcaggcattg gttctaagaa aacaggctgc cctgtccgtt ttactttttc
     9301 agccgtgcga tcagctaaac gctgaatgat ctcttggcgc ttttcacggt aattgcctac
     9361 attgactact acagacagct tatttcttgc taaacgatgg atgaagactt gtgccagata
     9421 ttgcaatgca ttcagtgttt ttccatgttt cccaatcagt atgccttgct tttgtgtttc
     9481 taaatggaaa acaaccatat tatttgattc tctttccatt ttgacaagag ctggagcatc
     9541 aagctgtttt gaaatttcag taagataaac tgccaattcc gttaaagctg cttcatcacc
     9601 tagctcactt acttcttctg ttttttcttc aagaatcgtt tcgttgacta cctcgatctc
     9661 agctgttggt tcttcttcca aaatttcttc tacagtctgt tctactgttt cagaaacttt
     9721 ttcgctgata cttggctgga tcgaaagccg tgcattcttt cgacccattc ctaggaaacc
     9781 tttttttcct tcttccagta tttcgatttc gacttggtct ttggccaaac ccaaatcagc
     9841 cagacctagt tggacagctt cgtctattgt tgcagcttca taaatcggca ttagcattac
     9901 ctcccctatt atttccgttt tttcttagga ttcattgctt tcttaagagc acgttctctt
     9961 tcgcggattc tccgtgcttc ttcttcacgc tcttttcgaa ttttgaaagg gttgttgatc
    10021 agcagcgttt gtacaacttg gaaggcattg gaaactaccc agtataatga aagaccgctg
    10081 gctaaattga cacccatcac taaaatcatt acaggcatca cgaaattcat gatcttcatt
    10141 gatgcattcg attcaatttg actcatgcta gataaatacg tacttgcaaa agtaaagatt
    10201 gctgctaaaa tcggcaaaat aaatgttgga tccgcgttcc ctaagttcaa ccataagaaa
    10261 tgcccttgtt tcaactctgg tacacgtgaa atagattgcc ataacgccat caagattggc
    10321 atttgtacta ataaaggaag acaaccagca tatggattga cgccattttc tgcatataaa
    10381 cgctgctgct cttctcttaa cttactttgt gtttccggat ctcttgaact atattgttgc
    10441 tgcagtgctt ttaatttcgg ttgtaattct tgcgttttac gcatgctctt tgtttggaaa
    10501 tgcatcaacg gcaataggat cacgcggatg atcagtgtaa ataaaatgat ccctatccct
    10561 gcattaccaa atgacaacgc cttgatcgcc tcagcaaagt aataaacaat ataacgatcc
    10621 caaattcctg tactctgtgc gctgacttcc ccagttccgc aaccggataa gacgatgacc
    10681 aaactaacga taccggccat caaaagtaaa cgtttgtatt tcttcactta ctcttttcct
    10741 ctctgtcgat tatttttgca agttttaaga cgtggactaa attggagcga acctcatcat
    10801 aagtcaaccc cttcacactt ggtctagcaa tcacaataaa atccaactcc ggatcaattt
    10861 cttcttttat agaataaact gctgctcgga tttttcgttt gacttcattg cggtttaccg
    10921 cgttgccgac cttttttcct acagataaac caactcgaaa atgaggctgt cccggttttt
    10981 ccaaacggta aacgacgaat ttgcggttag caaaagaatc tcccgtatgg aacacggctt
    11041 gaaactctcg ttcttttttt actcgatacg cttttctcat tagttttctt tccttttcta
    11101 tctctcactt acgctcataa tcataccata attacgattg tcctttcatc atttccctaa
    11161 aaaagagtat aaaaaaaacc actgaaaccc cagtggccta agctgaaaga acttttcttc
    11221 ctttgcgacg acggctagct aacacacgac gtccattttt agtactcata cgtttacgga
    11281 atccgtgaac tttttgacgt ttacgtttat ttggttggta tgttcttttc atatattcca
    11341 cctccaaaat gttcttatct attttataaa cacagacata ctttgatagt ataacgacaa
    11401 agtagtgatt ttgtcaatat aaaatagaag atcgattgtt aaaacttatc cacaagatta
    11461 tttttttcta tgggaatcct atgtggaaaa agttatgcac agggattatc cacagataat
    11521 aaaaggctgg ttttacacag aaaacacacg tgtaaaaaaa gtaatccaca atcaggcgat
    11581 ttcctgtgta ttccgtctcc taactattgg tatatctgta ttttttatcc acagacgcaa
    11641 gaggaaatct attggttttt acgagttttc cacctgtgca ttagtggtgt ggaaaacttt
    11701 ttttgacaac tgtgtttttc tcttttttct ttttgtcgat tgtgtggata attgtaatta
    11761 aaaaattttt ttcttcggtt tctgtggaaa actattgaaa aaaatgctaa attagtacta
    11821 gttattcact ttttaatgaa ggaggaggcc ttatatggta tccctcgatg ctttatggaa
    11881 tgaattaaaa gcaacatacc aaaaggattt atcgcctgct agctataata catggatcga
    11941 aacagcgaac cctcgaaccc ttgatcaaaa ccagctcgtt gttgaggttc ctagcaagat
    12001 tcataaagaa tattgggaaa aaaacctggc gacaaaaatc gttgaagtcg gttatatgtt
    12061 atcaggaaat gagattatcc ctcgctttat tactggcgaa gaagcagagc aagaagaagt
    12121 tatagaagaa aaaaatccaa aagttgtggc acctagtccg ctaaaaaaag ccatgctgaa
    12181 ccctaaatat acctttgata cgtttgtcat tggtaaagga aaccagatgg ctcatgcagc
    12241 agcgctcgtt gtagcagaag atccaggttc tatttataac ccgctcttct tttatggagg
    12301 cgtgggactt ggtaagactc acttgatgca tgcaattggt catcaaatgc tgcaaagtca
    12361 gcctaatgcc aaagtaaaat atgtaagcag tgaaactttt gctaatgatt tcatcaattc
    12421 gatccaaaac aaaacagcag aagagttccg tcaagaatat cgaaatgttg atttactgct
    12481 agtggatgac attcaatttt ttgcagaaaa agaagctacg caagaagagt ttttccatac
    12541 tttcaatgcc ttgtacaatg aagggaaaca aatcgtacta accagtgatc ggttgccaaa
    12601 cgagattccg aaactgcaag aacgccttgt ttctcgcttt gcatgggggc tgtctgttga
    12661 tattacaccg ccggatcttg aaacaagaac agcgatttta cgtaaaaaag cggcggctga
    12721 acgtctagag atcccagatg acacactaag ctacatcgca ggacaaattg attctaacat
    12781 tcgtgaatta gaaggtgcgc ttgttcgagt gcaagctttt gctgcgatga atagtgaaga
    12841 tatttcgact agtctagctg cagacgcact gaaaacgtta aaatcaggaa aaggacatcc
    12901 tcaattgtca atcctgcaga tccaagaaga agtggcaaag tattatcaca tccaattgaa
    12961 agatctcaaa ggaaagaaac gcgtcaaatc tattgttgtt cctagacaaa tcgctatgta
    13021 tttggcacgt gagctcacag ataattcttt accgaaaatc ggagctgaat tcggtggcaa
    13081 ggatcataca acggttatcc atgctcatga aaaaatccag cagctgatgg attctagtgt
    13141 cagtatgcaa aatgaagtat cagaaatcaa aaacttttta ctaaattaat ttgtcgattc
    13201 tatcaactga aaatagcatg tggataaaag aaaaaaacgt tcaaaagtta tacacacttt
    13261 ttccacagct gttttttcgt ttctctctta cgttttttga gttttccaca gaatcaacat
    13321 gccctattac ttttattatt ctttttaact aataataaat aaacaaacat tcaaaggaga
    13381 tacatcatga aagttacttt aaaccgagct agctttatgc aggaattgca aactgttcaa
    13441 cgagctattt caagcaaaac cacgatccct attttgacag gtgtaaaaat cacactgaca
    13501 caagaaggtt tgactttgac ggggagcaac gctgatatat caattgaaac ttttttgtct
    13561 gttgaaaacg aaaaagcaaa tatgcaaatc gaatctactg gttccattgt tttacaagca
    13621 cgtttcttta gcgaaatcat tcggagactt cctgaagaaa catttacttt agaagtttta
    13681 gaaaataaac aagtagcgat cacttctgga aaagcgaatt ttatcgtaaa tggattagat
    13741 gcagataact atcctcatct tcctgttgtc gaaagccata accagatgaa attacctgta
    13801 cacgtattga ctaaactaat caacgaaaca gtttttgctg tctcacaaca tgagagtcgt
    13861 ccaatcttga caggtgtgca tttcatttta tctgataatt ctttattagc tgtagctact
    13921 gattctcacc gtctaagtca acgcgtgatt ccagtagaac aagcggctga tcattttgat
    13981 attgttattc ctggaaaaag tttgatcgaa ttatctcgct cattaacaaa tgaagaagaa
    14041 atcgtcgaaa tcagcattat ggaaaaccaa gtgttgttca aaacagaaac gatgtatttc
    14101 tattcccgtt tgctagaagg aaactatcca gataccaatc gtttgattcc ttcaagtttt
    14161 aatacagagg ttgaattttc tgttcctagc tttttagcgg cgatcgaacg ggcttcttta
    14221 ctttctcatg aaggccgtaa caacatcgtt cgtttatcta ttcgtccaga tgcggttgtt
    14281 ttatacggaa attcgccaga aatcgggaaa gtagaagaaa gcttgagtta tacagcaagc
    14341 agtggcgatc cattagatat ttctttcaat ccggattata tgaaagcagc gttgcgtgca
    14401 tttggagata tgagcatcaa agtgaaattt atctctgcta ttcgtccatt tacattggaa
    14461 ccaacggaag atggcgttca atttattcag ctgattactc ctgtacgtac aaattaacaa
    14521 tgattttcaa tgttcttgaa aatttaattg aaaagaaata gaaaaaataa aattttaaac
    14581 agaaggccct aaaatctctt ttaaggcttt ctgtttattt ttgtttaaat cacctttttt
    14641 agattaaatc gtcttatatg gaaaaatata tggataaatt tgttttattg cgaaaaaaaa
    14701 ggtataatag agtatacttt taataatgaa aatgagggat gggcattgaa acaacaagtc
    14761 attctaaata cggaattcat gacgttgggc caaatgttga aagaagtcac agttatcggt
    14821 agtggcggac aagcaaaatg gtatttggca gaaaacactg tgttagtcga tggcgaacca
    14881 gaaaatcgtc gtggacgcaa actttatccc ggcatgatgg ttgaagttcc agaagtagga
    14941 acttttttta tggtaaaaaa aggaaacgac gataatgagg ctgaataagc tgtatttaaa
    15001 aaattatcga aattacgaag agctgaacat cgaattttcc aagaacctcg tcatcttttt
    15061 aggagaaaat gcgcaaggaa aaacgaatct tttggaaagt atctacgtat tagctatgac
    15121 gcgaagtcat cggacaagta gtgagcagga attgattggc tggactgacg atcaggcgat
    15181 gattcaagga gagatcacaa aaggttcatc cactcttcca ttagaaatct tattatctaa
    15241 aaaaggccga aaaaccaaga tcaaccatat cgaacagaaa aagttaagta cttacgtggg
    15301 acaaatgaat gtcattttat ttgcaccaga agatctttct ttagtaaaag gcagcccgca
    15361 gaccaggcgg aagtttttag atatggaatt aggccagatc aatccaatct atctttatga
    15421 tcttgtccaa taccaagcaa ttttgaaaca aagaaaccag tacttgaagc aattgaatga
    15481 aaaaaaacaa actgatttgc tttatttgga tattttgtcc gaacaactag cagcgtttgg
    15541 cagcaaagta ttgaaagcaa gagcacagtt cgtcaagcga ttggagtttt gggctaattc
    15601 tttgcatcag caaatcaccc atcaaaaaga gcagctggaa atcgagtatc tcaccgcagt
    15661 cgattcttta gaaacacata cgcaagagca aatccaagaa caatttctcg cacttttgaa
    15721 ccaaaataaa aagaaagacc tttttcgggg aacaacgaca gttggtcctc atcgtgacga
    15781 tctttccttt tttattaatc agaaaaatgt gcagacttat ggatcgcaag gacagcaaag
    15841 aacaactgca ctaagtgtca aattagcaga aatcgatttg attaaagaag agacagggga
    15901 atatccaatc cttttgttag atgatgtgat gagcgagctg gatgataatc gtcaactcca
    15961 tctgctagaa acaatcgaag gaaaagttca aacgttctta acaacaacga cacttgacca
    16021 tgtaaaaaat aaaatgactg ttgaacctga gattttttat gttcaacaag ggaaactaaa
    16081 aggagaagaa actgaatgac agaagaaaga agtttagtag aacgcgctaa agagtatgat
    16141 gccagtcaga ttcaagtact tgaaggactt gaagccgttc gtaaacgacc tggcatgtat
    16201 atcggttcga ctagttctga gggtctgcat caccttgttt gggaaattgt cgataattcg
    16261 atcgatgaag tattagcagg ttttgcaacg aaaatccatg tgattattga aaaagacaac
    16321 agtatcaccg ttattgacga cggtcggggg atacctgtag atatccaggc aaaaactgga
    16381 cgtcctgcag ttgaaacggt ctttactgtt ttacatgctg gaggaaaatt cggcggtggt
    16441 gggtacaaag tttctggtgg acttcacgga gtaggatctt ctgttgttaa cgcgctttct
    16501 acacagcttg atgtcaaagt atacaaagaa ggaaatgtgt actatcaaga atatcgtcgt
    16561 ggagctgtag tggacgactt aaagattatc gaacaaacgg atcgccatgg aacaacggtt
    16621 cactttacgc cagaccctga aatttttaca gagacaactg agtttgattt ttcaaaattg
    16681 gctacccgga tccgtgaact tgctttcttg aaccgcggga tgcgtatatc gattgaagac
    16741 aaacgagaag aagaaccagt catcaatgaa taccattatg acggcgggat taaaagttat
    16801 gtcgaatact tgaatgcaaa caaaaccgtg atttttccag aacctgtata tttggaaggt
    16861 gaacagcaag atatcgcagt tgaagtctct atgcaatata cagacggcta ccattccaat
    16921 atcatgagtt ttgccaacaa tatccatacg tatgaaggcg gaacacatga atcaggattc
    16981 aagactgctt taactcgtgt gataaatgat tatgcccgaa aacaaaagct gatgaaagaa
    17041 aatgacgaca acttgaccgg tgaagacgtg cgagaaggat tgacagctgt tatttctatc
    17101 aagcatcctg accctcaatt cgaaggacaa acaaaaacaa aattgggcaa ttccgaagta
    17161 cggacagtca ctgatcggtt atttagcgaa catttcatga aattcttgct ggaaaaccca
    17221 agtgtgggcc gtcaaattgt tgaaaaagga ttactagctt ccagagctcg tctagcagcg
    17281 aaacgtgcgc gtgaagtaac gagacgtaaa ggtgctttag agattagtaa tctgccagga
    17341 aaattagcgg actgctctag caacgatcct gaaaaatgcg aattgttcat cgtcgaagga
    17401 gattcggccg gcggatcagc taagcaaggt cgtaatcgag agtttcaagc catcttgcct
    17461 attcgtggga aaatcttgaa tgttgaaaaa gcaagcatgg acaagatctt ggcaaatgaa
    17521 gagatccggt ctttatttac tgctatgggt acagggtttg gagaagattt tgatgtatcg
    17581 aaagctcgct accacaaatt agttatcatg actgatgccg atgtcgacgg cgcgcatatc
    17641 cgtacattgc tgctgactct tttttatcgt tacatgcgtc ctattgttga agctggatac
    17701 gtctatattg ctcagccacc tttatacggg gtaaaacaag ggaagaatat tacgtatgta
    17761 caaccaggaa aaaatgcaga agaagagttg aaacaagtcg ttgcttcact tcctgcctca
    17821 ccaaaaccaa gcgttcagcg ttataaagga cttggagaaa tggatgatca tcaactatgg
    17881 gaaacaacta tggacccaag caatcggatg atggcccgcg tcagtgtgga cgatgctatt
    17941 gcagcagatc agatatttga aatgttgatg ggggatcgag tagaaccccg tcgtgcattc
    18001 atcgaggaaa atgcacacta tgtgaagaac ttagatattt aatcatgaag gaggaaaaag
    18061 aatgagtgaa gaaatcagag aaaacatcca tgatgtcaat ctaaccagcg aaatgaaaga
    18121 ctccttcatc gattatgcga tgagtgttat tgtcgcacgt gcacttcctg atgtcagaga
    18181 tggtctgaaa cccgttcatc gccgtatttt atacggcatg aacgaattag gtgtaacacc
    18241 ggataaagcc cataaaaaat ctgccagaat cgtcggagat gtcatgggta aataccatcc
    18301 tcatggagac tatgcgatct atgagtcaat ggtacggatg gcacagccat tcagctaccg
    18361 ttatatgcta gtggatggtc atggaaactt tggttctgtt gacggtgacg gtgccgccgc
    18421 tatgcgttat accgaagcac ggatgagcaa aatcgctaca gaaatgctgc gtgatatcaa
    18481 taagaacact gttgatttcc aaagcaacta tgatgataca gaaaaagaac cagttgtact
    18541 acctgctcgc ttcccgaatc ttttagtgaa cggaacaacg gggatcgccg taggtatggc
    18601 cacgaatatc ccacctcata acttgtctga ggtagtagcg gctatcgatt tgctgatgga
    18661 taatcctgat gtgacgacca atgaattgat ggaagtatta cctggaccag attttccaac
    18721 aggtggtttg gttatgggaa aatcaggaat ccgaagagcg tatgaaacag gtaagggttc
    18781 tattaccgta cgtgcaaaag ttgagattac tgagatgcca aatggtaaag aacggatcat
    18841 cgtgacagaa ttgccttata tggtcaataa agcaaaattg atcgaacgga tttctgaact
    18901 gcacagagac aagcgtatcg aagggatcac agatttgcgg gacgaatctt cccgtgaagg
    18961 tatgcggatc gtcattgaca tccgtcgtga cgccagcgca tctgttatct tgaataactt
    19021 atataaattg acatccttgc aaaattcatt tggattcaat atgttggcga tcgaaaaagg
    19081 tgtgccgaaa gttttgagct tgaaacaaat tcttgaaaac tatatcgaac atcagcgcga
    19141 agtcatcaca agacggacag tctttgaaaa agaaaaagca gaagcaaggg cacacatttt
    19201 agaaggtttg cgtattgctt tggatcatat cgatgaaatc attgcgatta tccgcgggtc
    19261 taaatcagat gacgaagcaa aagcgacgat gatcgaacgg ttcgatttat ccgatcgcca
    19321 gtctcaagct attttagata tgcgtttacg ccgattgacc ggtttggaac gggaaaaaat
    19381 cgaaaatgaa taccaagaac tcttaaaact gattgaagat ttaactgaca ttctggcaag
    19441 accagaacgt gttacagaaa tcatcaagaa tgaattagca gacttgaatc aacgatttgg
    19501 tgataaacga cgcacagaat tactagtcgg tgaggtctta agtctggaag atgaagattt
    19561 aatcgaagaa gaagaaatcg ttattacatt gacaaacaat ggttacatca aacgtttggc
    19621 aaataatgaa ttcagagctc aacgaagggg tggacgtggt gtccaaggaa tgggtatcca
    19681 caatgacgac ttcgtcaaaa atctggtttc ttgttctacc catgatacat tgttattctt
    19741 tacgaataac ggaaaagtgt atcgggcaaa aggatacgaa attccagaat acgggcgcac
    19801 agccaaagga ataccaatta tcaatttact aggtatcgat tcgagtgaaa gcatccaggc
    19861 aatcattgcg gtgacgggag aagcagaaga aggccactat ctcttcttta cgacgcgtca
    19921 aggtacagta aaacgtactt ctgtcactgc ttttgctaac atccgaagta atggtctgat
    19981 cgcaattggt ttgaaagaag acgatgagct cgtcaatgtg ctactgacag atggtcaatc
    20041 taatatcatt attggaacac ataacggcta ctctgtcact ttcaaagaag aagcagtccg
    20101 cgatatggga cgtacagctt ccggggttag aggaatacgc ctgcgtgagg aagattatgt
    20161 cgttggggca gccttaatga aggaagatca agaagtatta gtgatcacag aaaaaggtta
    20221 cggaaaacgg acaaaagtat cggaatatcc agtgaaaggc cgcggaggta aagggatcaa
    20281 aacggcgaac atcactgaaa aaaatggtcc actagctgga ttgaccactg tttctggaga
    20341 tgaagacatc atgctgatta cagataaagg tgtcattatc cgtttcaacg tatcgactgt
    20401 ttctcaaact ggacgttcaa cattaggcgt acgtttgatg aagatggaag ctgatacgaa
    20461 agttgtcacg atggcagcag tcgaaccaga agctgcagaa caaacagttg aagaacaagg
    20521 atcagaagaa tagccatcaa gactaattgt gtaagctagc aagaatgacc gattaaaaaa
    20581 tctggttatt cctgctggct tttttgatta gttgaatttc tcttaaaata ttcgaaactg
    20641 ttcattctgt attgcttttg accaaaatag agtgtataat cagagcttgt gagtagtcta
    20701 attaattaga taactctcct tgctcttagg aacctaagag ccgaaagtcc acagggaggt
    20761 gaatatcaat ggaaaacacg aaatatgaaa tcatgtacat tattcgtcca aacattgatg
    20821 aagaagcaaa aactgcttta atcgaacgtt tcgatgcaat cttgaaagat aacggagcag
    20881 aagttatcga atcaaaagat tgggaaaaac gccgtttcgc ttatgaaatg aacggttacc
    20941 gtgaaggtat ctatcacatc gttaaagtat cttctccatc atcagcaaat gctgtcaatg
    21001 aatttgaccg tcttgctaaa atcaacgacg atatcattcg tcacatgatt gttaaagaag
    21061 aagcttaatt gttgtttcat gtgaaacaat agaaaacgat gagaggagat gactattttg
    21121 attaataatg ttgtattagt tggacgtctg acgaaagatc cagatttgcg ttacacagca
    21181 agtggtacgg cagtcgcaac atttactttg gctgtgaatc gtaattttac aaaccaaagc
    21241 ggcaatcgcg aggctgattt tatcaactgt gtgatttggc gcaaatcagc agaaacttta
    21301 gcaaactatg ctcgtaaagg aacactttta ggtgttactg gacgtatcca aactcgttct
    21361 tatgataatc agcaaggaca acgtgtatac gtgacagaag tagtagctga caacttccaa
    21421 ttgctggaaa gtcgttctgc atctgaaaat cgccaacaaa gcggcggatt ccaaagttct
    21481 ggtcaatcag ctggcggatt tggcggaaac aataactcta atcaaacatc tcaatcatcc
    21541 aacggtatgc ctgatttcga ccgtgatact tctgacccat tcggctcaag ttcaacgatc
    21601 gacatttcag acgatgattt accattctaa acgaatttga taggagggaa atagaatggc
    21661 acaacaaaga agaggcggac gtaaacgtcg taaagtagac tacattgctg ctaaccatat
    21721 tgaatatatc gattataaag atatcgaatt actaaaaaga tttatttcag aacgcggtaa
    21781 aatcttgcca cgtcgtgtaa ctggtacagg cgctaaaaac caacgtaaaa ttactgttgc
    21841 aatcaaacgc gctcgtatca tgggcttgct acctttcgtt agcgaagact aataaatcct
    21901 aggaattgaa tgactgatcc ttttgatcag ctattcaatt cctttttttc tgtaaaaata
    21961 acctctattc gtttagtcgc tcgaatgacg aaagttatgg taaaatcaaa ttagtcatat
    22021 atgggaggaa aattatggaa aataaaaaca atcatttatc cccgaaacct ctcttcctta
    22081 tcctgtttat attaatcgaa gtattggtag tcttaatttt accatttcgt tttgttagcg
    22141 cttcggtcat tctattgatg aatttatggg gtgttcgcta ttggttgaaa atgaaacgtt
    22201 ggcttatttt aaataaacgt gaaaaaatcc agcaggcttc gactgtagct gaaaccaatc
    22261 tagcttatgt ctcagaagtc atgcctgtag gagtgattgc ttatcagcca tcaagccaaa
    22321 aaatcgaatg gctcaatcca ttagcattga aaatcaaaga tcaaagtgga ttaacagagg
    22381 aagaattgct agatactttt tttactgcaa aagaaaaaaa gaaaaaccaa gtctatctag
    22441 cagataaaac atttcagttt gatatggata cagtaaaggg tgttgtttat tttaatgata
    22501 ttacccaaaa ccagttgtta aaactccatc agacgaacag tcagccggtg attggtattt
    22561 tatctattga taactatgca gatgccattg ataaattgga tgacaaagag atttcttatt
    22621 tgaactcttt cgtcactaca ctagtttctg actggatgaa tgaataccat gtctttttca
    22681 aaagaatcaa cgcagaacgg tttttcttcg tagcacagat gatcgatctg aaaaagatga
    22741 tggataaaaa atttgatttg ctggatcgct ttcgagcaga agctgaaaaa cagagctcgc
    22801 ctatcaccct tagtatgggg attgcttatg gctcaagaac cctcgatgaa atcggtggag
    22861 aagctcagaa taatttagat gttgctttag tccgtggagg cgaccaagtt gtcgtgaaag
    22921 aggtaaaaga aggagcaaaa cctgtttatt atggggggaa atctgctaag aatgtcaaac
    22981 gcacgcgtgt tcgttctcga gcgatgagta ccgctttgcg tcggattttt gatgaaacag
    23041 gcgatgtgtt tatcatgggg cacaagtttc cggatatgga tgctttaggc tctgcttttg
    23101 gtgtcagttg tctggcacgc ttcaaccaga aaaaagctta catcgttatc aacgagaacg
    23161 agatcattcc agatgtagaa cggtgtcttg aagaaatcca taagcatcct gaattagaaa
    23221 tgcaactaat ctctccagaa cgtgccatag agctgaaaaa agaagaggac ctcctctcgt
    23281 gatggtggat taccataaac cttctctatc gatctctcag ggcctatatg agcaatttga
    23341 taagattgtg atcattgatc accatcgtcg tggggaagag tttccaagta aacctctgct
    23401 gacttatatc gaatcttcag cttcttcagc ttcagagcta gtttctgagc tgatccaata
    23461 ccaaagcagc aaaacaaatc gcttagatcg ttttgaggcc acattattgc ttgcagggat
    23521 ggttgtagat acaaatagtt tcaatgtccg tacaactgca cgaacttttg acgttgccag
    23581 ctatttaagg tcttgtggag cagacgcatc cttagtacaa tatttattga gctcggattt
    23641 agcgacatac ttggagatca gcaatttgat tgctggaagc gactatgtga cttctgatat
    23701 tgttgtggcg gcagggacag acgaaaaaga gtataatagt gttatagcag caaaaacagc
    23761 agatacattg ctttcgatga tcaatatcaa tgcagctttc gtcattacaa agcggacaga
    23821 cggcttgatt gggatcagtg ccagaagtac cggcacgatc aacgtccaaa tcatcatgga
    23881 atccttaggt ggcggaggac acttcacaaa cgcagctact caactggaaa atacgacagt
    23941 tgaggaaaca aaacagaagc tatttgctgc aatcaaagaa aatatgaatc aaatatatga
    24001 taaggagtaa tccaaatgaa agtaattttt ttacaagatg taaaaggaaa aggtaaaaaa
    24061 ggggacatca aagaagttcc agcaggttat gcacaaaatt atctaatcaa aaataacttg
    24121 gcaaaagaag caacgaaaag cagtatcagt cagttagcag gacaaaagaa agcacaagaa
    24181 aaacacgaag ctgaaatctt ggaagaagct aaaaagttaa aagaattctt ggaaaaagaa
    24241 gatactgtag tcgaattgaa ggcgaaagca ggggaagaca gccgtttgtt tggttcgatc
    24301 ccttcaaaac aaattgctga agggttaaac aaacaataca aaatcaaatt agataaacga
    24361 aaaatcgaat tagaaaatcc gatccgttca ctaggctaca caaacgtacc tgttaagctt
    24421 catcatgagg tgacggctac gatcaaagtt catgtcgtac aagaataaca aatcttgata
    24481 gcgatgttca gctggtaagt ataaccagaa ggaaaaaaga caaaccgaaa tttatctgag
    24541 aaaacagctg cagcaatgaa agcaaaagct gcaaatcgat ttcagattga tttcggtttc
    24601 ttttttggga acagcaaaat agcataaaga aaacgagtat aataaaagag aactattttt
    24661 ttattacact ttcggtacga atgatgactt ttctctcatt ttcttgtaaa atgaagcaat
    24721 tgaagacaag gagcgatacg tatgaatgaa gtgtggcagg atcgaatccc accgcaaaat
    24781 attgaagctg aacaagcggt tttaggctct gtttttcttg acgcagaaac gatcattgat
    24841 gccatggagt acatagagcc aaaagacttt tatcgtcgtg gccatcaaat tatttttgag
    24901 acaatgatcg agttaaatga tcgtaatgaa gcgattgacg tggttactgt caaagaccgg
    24961 ctggaacaag ccaatttgtt agaagatgcc ggtggtttaa gttatctctc agacttggca
    25021 ttagcagttc cgacagcagc aaatatcgtc tactatgcga aaatcgttga agaaaaatca
    25081 ttgctgcgta cattgatcca gacagcaaca ggaatcgtta cgaaaggatt cgagcaagga
    25141 gaagaagttc aaacaatttt agatgatgcc gaacgcagta tcttggaggt ttcggaaaaa
    25201 agaaatcgaa gcggcttttt atctattgct gaagtactga actccacgat tgaaaatatc
    25261 gatcgactag ctcaaaacaa tgaagaaatc acaggtctac caactggcta tcaaggtctg
    25321 gataaaatga cagcaggttt ccagcccgaa gaactaatca ttcttgctgc acgtccagcg
    25381 gtaggtaaaa cagcgtttgc attgaatatt gctcaaaatg taggaacaaa aacagatcgt
    25441 tctgttgcga tatttagttt ggaaatgggg gcagaatctc ttgtaaatcg gatgctttgt
    25501 gcagaaggtt cgattgaggc cagccattta cgtacaggtc agctttcgga agaagaatgg
    25561 tcgaatctga tcgttgcgat ggggagtctt tctcgagcaa atatttttat cgatgataca
    25621 ccagggatca aaatctctga aatccgtgcg aaatgtcgga aactagcgca agaaaaaggc
    25681 aatctaggct tgatattgat cgattatttg cagttgattg aaggtaacgg taaagagaac
    25741 cgtcaacaag aagtatcaga tatctctcgc caactgaaaa aactggcgaa agagctgaaa
    25801 gtacctgtca ttgctctttc acagttatct cgtggagtag aacagcgaca agacaaacga
    25861 ccagtgctaa gtgatattcg tgaatccgga tcaattgaac aagatgcgga catcgtagcc
    25921 ttcttgtatc gagatgatta ttatgaaaga gaaggcggag atgacgatga tggaaacgag
    25981 ccaaaaaatg acaacgtcat cgaagtcatc atcgagaaga accgaagcgg tgcacgagga
    26041 acagttgaac tactgtttat caaagaatac aataagtttt cgtcgctttc gccaagagaa
    26101 gaattttaaa gaagaggttg tgagccttga gcaatcccga gagctctcgt aagaagatgc
    26161 aaggagtaac cgcaggaacg actagagtac ttaatttaaa cagatctcca aagggattgt
    26221 gacaaaagtc ttgtcacagt ccctttttcc gaataaacgg tgttcaatca gctgaccctt
    26281 ggtattagct cagcaaacgt caaaatatga ggaactattt tgacgtttgt ttctctaata
    26341 ctcaggtcaa aacgctgatc ttacgacctc ttttccttaa acggtgttct cctgccaact
    26401 cctcggtcac aagtcacaat atcatcaaac atgagaagca gttttttgaa attgctcctt
    26461 gtgactcaga gttaaacggc aggctcacaa cctctttctt aaacggtgtt caaaagcttg
    26521 catctgcggt aatacgccca atcaaacgaa aaatatgaga agctattttt gtttggctgt
    26581 tcttattact tgatgcagga cagctttttc acaacctctg attcacggtg ttccaaaagt
    26641 agcttcttcg aaaaataagt cgaaatttca caaaaatttg agaagcaatt ttcgtacatt
    26701 ccttcttatt tcttgaagct gaccacttct gttacaacct cttttttaat aaccattcta
    26761 aaaagataaa gttcgttttt taagcgtttt tataaaataa aaataaaaat cattcgattt
    26821 tatttgaaat atgtatctat tattgataca atggttcagg attaaataat atagaacgag
    26881 gtgttcacat gtcatctgta gtagtagtag gtacgcaatg gggcgatgaa gggaaaggaa
    26941 aaatcacaga ctttctcagt gaaaatgctg aagtgattgc acggtaccaa ggtggcgaca
    27001 atgcagggca cacaattaag tttaacggtg tgacttataa actgcatttg attccttctg
    27061 ggatttttta taaagacaag atcagtgtga tcggaaacgg cgttgtagtc aatcctaaat
    27121 cattggttaa agaattagct tatttacatg aaaaaggtgt agaaacaagt aatttgcgta
    27181 tttctgaccg cgcgcacgta atcttgcctt atcatatcaa attggaccaa ttacaagaag
    27241 atgctaaggg cgaaaataag attggtacaa cgattaaagg aatcggacct gcctatatgg
    27301 ataaagcagc tcgtgtaggt atccgtattg cagacttatt agataaagaa atttttgaag
    27361 aacgtcttcg tttgaatcta gatgacaaaa accgtcaatt tgtaaaaatg tttgattcag
    27421 aaccacttga ttttgacgat atttttgaag aatattatga atacggacaa caaatcaaac
    27481 aatacgtcac agatacttcc gttatcttga atgatgcttt ggatgcaggc aaacgcgtgt
    27541 tgtttgaagg cgcacaaggt gtaatgctgg atatcgacca gggaacttat ccttttgtta
    27601 cttcttctaa cccagtagcc ggtggggtaa caatcggaag cggtgtaggg ccttcaaaaa
    27661 tcaataaagt tgtcggcgtc tgcaaagcct atacgtcacg tgtcggtgat ggaccatttc
    27721 caactgaatt atttgatgaa acaggagaac aaatccgcga agtaggacga gaatacggta
    27781 cgacaactgg tcgtccgcgt cgtgtaggct ggtttgattc tgtagttatg cgccattcta
    27841 aacgagtttc aggtattacc aacctatctt taaactcgat cgatgtatta agtggattgg
    27901 aaacagtaaa aatttgtacg gcttatgaat tagatggcga actaatctac cactatccag
    27961 caagcttgaa agagttgaac cgctgcaaac caatctatga agaattgcca ggctggtcag
    28021 aagacattac aggatgcaaa acacttgcag aactgccaga aaacgcacgt aactatgtac
    28081 gtcgtatctc agagcttgtt ggtgtacgta tctcaacatt ttctgtcgga cctgatagaa
    28141 cacaaacaaa catcttagaa agcgtctggg cgcaaatcta aggataaaaa cgacgactga
    28201 atcaggacgt tcttaccaga gcgagtcgaa gtgtttatct atacgataat aataacttga
    28261 acactgttta ttcagaataa gggactgtga caaaaaccgt gtcacagtcc ctttttccga
    28321 acaaacggtg ttcaaaagct tgcatctacg gcactaagcc caatcagatg aaaaatatgg
    28381 agtgctattt ttatctgatt gttcttactg cttgatgcag agcagctttt tcacaacctc
    28441 tccactaaac ggtgttctcc tgccaactcc tcggtcacaa gtcacaatat tcaacaaaca
    28501 tgagaagctg ttttttgaaa ttgttccttg tgactcggag ctaaacggca ggctcacaac
    28561 ctcttggtaa acggtgttca atcagctgac cctcggtatt agctcaaaaa acggcaaaat
    28621 atgaggaact attttttccg tttttttctc taatactcag gtcaaaacgc tgatttcaca
    28681 acctctgatt cacggtgttc cagaagtagc ttctacggaa ataagccgaa atttcacaaa
    28741 aatttgagaa gcaattttcg taaattcctt cttatttctt gaagctgacc acttctgtca
    28801 caacctctta ttttgattag aacttgcgaa aataaaccgg ttaaagtgtg tctagcgcaa
    28861 gagatttgct ataatagacg ataagggtaa aatgtaacga gaaggggttg aaaaatgtgt
    28921 atcaaattgt aacagattct tgttgtgatc tgccatacca tgtattagca aaagaaaaag
    28981 ttgatttttt atcaatgaat ctccaattga atgatcaaga gttagtagat gacctcggaa
    29041 agacattcaa ttatgaccgc tacatgaatc agctgaaaaa tggtgcgatg cctacgacat
    29101 cacaaatcaa tgttggccga tatttagaat ttttccgttc ttatgcggaa aaacagattc
    29161 ctgttttata tgtggctttt tccagtggat taagcggctc ttacagtagt gcgcttcaag
    29221 cggttgaatt gctgaaggaa gaatatgaag accctgagat ctatgttttt gatacaaaag
    29281 ctgcaagtat tggggaaggg cttttagtat tggaagctgt aagattgaaa aaagaaggta
    29341 aaagcatcga agaaacccta gagtggctgg aaagtaatta tttgaaagtc cattcatggg
    29401 taacagtaga cgatctgaaa tatctagaac gaggcggtag gatttccaaa gcaagtgcta
    29461 ctcttggcag tctattgagt gtaaagccta ttattacggt ggataaagaa ggaaggctga
    29521 cgaatgttga caaagttcga ggaagaaaca agtcgatcca gacaatcgtc aatgagacgg
    29581 taaaaacaat cgttgcacca cttgatcaaa tcgtttatgt ggcttacgct ggggatctag
    29641 agagcgcgga gaaggcaaaa cggcttttgg aagagcagat aaagatgaaa gatgtgaagc
    29701 tttatccctt aggaccaacg atcgccagtc acacaggcta tggctgtatc gcgatttttt
    29761 cgatgggaat cagtcgataa aagcagtaac tcattctgta aaaaagccca gaaattgatt
    29821 gtaacaaaaa cagcgactct taaaagatag atgagcatcc tatctcttag aggtcgctgt
    29881 ttttttattt tttaagctaa ataggccatt atgcccataa ctcgttcaat tgtttttgaa
    29941 tatctgcatt ttccaaaaat tcatcatatg tcgtatcagc tcgatcgatc acacctttat
    30001 ccgaaacggc aatgatgcgg tttgccaatg tttggataaa ttgatggtca tgtgacgcaa
    30061 ataagattga gccagtaaat gccatcaagc cgtcattcaa tgctgtgatt gattctaagt
    30121 ctaaatggtt cgttggatca tctaatacaa gtacgttagc tttcgaaagc atcatttttg
    30181 aaagcatgca acggactttc tctccaccag ataaaacatt cactggtttc aatacttctt
    30241 caccagaaaa caacattctt cctaagaagc ttcttaagaa ggtgttatca tcttcttctt
    30301 tacttgcata ttgacgcaac cagtctaaaa tcgttagatc agtatcgaat tctttcgttg
    30361 tatcctttgg taaataagaa ttacttgttg tcacacccca acgtactgtt ccagtatctg
    30421 gcgtaatttc acccatgata actttgaata gcgttgttgt tgttatatca ttttctgcga
    30481 cgaaagcgac cttgtcttct ttgctcaaat taaaagatat atcatctaaa attttctttc
    30541 catcaatcgt tacacttaca ttttctacct gcaataagtc gtttccaatc tcacgttcag
    30601 gtttgaatcc aacgaatgga taacgtctag aagaaggttg gatatcgtct aaagtaattt
    30661 tttcaagcat ttttttacgt gaagttgctt gttttgattt tgatgcattc gcactaaagc
    30721 gggcaataaa ttcttggagt tctttgattt gttcttcttt tttggcattt gcgtttgctt
    30781 gaagtttagc cgctagttga ctagattcca accaaaaatc ataatttcct acataaagtt
    30841 tgattttacc aaaatctaga tccgccatat gtgtacatac tttgttcaaa aagtgacggt
    30901 catgggatac aacgatcaca gtattttcaa aattgatcaa aaattcttcc agccaattga
    30961 tcgattggat atccagaccg tttgttggtt cgtctagcaa aagaacatca ggtttaccaa
    31021 atagtgtttg tgctaataac acttttacct tttgtccacc agttaattca ctcatttgct
    31081 gatggtgcaa ttcttcaggg atgttcagac cttgcagtaa aacagctgct tctggttcag
    31141 cttcccatcc attaagctca gcaaattctc cttctaattc agctgctcga ataccatctt
    31201 cgtcagtgaa atcctctttc atgtaaatcg catctttttc tttcagcact tcatacagac
    31261 gcttgtgtcc catgatgact gtttcaagta cagtatagtc ttcatagtcg taatggttct
    31321 gtttcaatac ggccatccgt tcatctggtc ccatagtaac ggaacctgtg gaaggctgca
    31381 gatcccctga taacacttta aggaacgttg atttacctgc accatttgca ccaatcaagc
    31441 catagcagtt tccgggggta aatttaatat tcacatcatc aaatagtttg cggtctgaaa
    31501 agtgcaaact cacatcattt acagtaatca atttttttcc tcacttttat cattattagt
    31561 tttgacaagt cttatagaat tatatagggg aaaggtaaaa gattcaaggc aatcgaacat
    31621 tctttgtgtt tcacgtgaaa cagaatgaaa aaaataaaaa taaaagcgga gcgaaaatag
    31681 ctactatagg atttattagt ttgcaacagc ataatttttg acgttattta taagagggag
    31741 tactataaaa ctgtaaaaga aatgaaagaa ggattgaaaa tggatgaaaa aagaaccatc
    31801 gactggggct cattgatttt gggaatttta tttgtacttg tctcattgtt atcatttcaa
    31861 gaccctgtcg gaaatttagt tgcaattgta gtagtctttg cgatttttgc ctttattaaa
    31921 gggatatttg aactgtttgt acggaacaga ttaaaagagc taacaggata taaaggaaag
    31981 atgcccttaa taatcgggat catcgatatt ctagttggcg tctttttctt attcaatatt
    32041 ggtgcaggag tcgcagcatt gccttttgtt tttgcagtat ggtttattgc tgattcagtt
    32101 ttagcgttat ttactgctga cttggcaaga ggagtaagtg aaggatatta ttggtttacg
    32161 atcatcgtca atattttagg aattttatta ggaattttct tattgtttaa tccaatttct
    32221 tctgcgttga cattaagctt tttagttgga ttctatttta tgttatttgg tatcacacat
    32281 atcgtctatg catttagata agtaaaatca aacaaataaa aaagccggct tccgattaca
    32341 gttttactgt tgtaattgga agccggcttt tttatcatgg acaaatatgc acgaggtgat
    32401 ttttaggtgt cgagacaaat ttatgcaaaa atgtgagaag ctatatacac aaattttatc
    32461 ttaatactcg aagcatagcg cagttgtcac aacctctttt catataattc attcaatact
    32521 ggcaaatcat ggacttcata tttttctttg aatgcttgga tttcttcttc agaatatttt
    32581 cttggatcta aatgcagatc ttctactggc aatgggcgct tgttattgat cttcacatcg
    32641 attactacag gacgatctga ttttgcagct gcatcaaagg caaatcgaag ttgcgagtat
    32701 tctgtgactg taaagctatt tgccccgagc gcttctccaa ctttaccgaa atctgcatct
    32761 tctaaaaata caccaaattt cttttgttcc gtatcttctt gttctgcttc gatgaaacca
    32821 aaagaatcat tcgaaaagac aacattaata attggaagct gatatttgac ttgtgtaatg
    32881 atatcttgca tgaccatagc aaacccgcca tcaccactta aggtaaatac ttgtttttct
    32941 gggtagctta gttgtgcggc aattcctcct ggcacaccat tacccatagt tgcgaaccat
    33001 ccagatgtcg tatgtttttg tttaccgttc atattcaata aacgaataga atggatagtc
    33061 gtgttaccga catctgtgac gaaaatcgca tcgtcttcag caatacgatt gatttcttta
    33121 tagacagcct ctggacgaat cggttcttcc tctcgatctt caaaagattt caaccaattt
    33181 acccattttt ctttattttc ttgatttgct aggtaccagc tatcagcagg gcgagcatcc
    33241 cctaactcga caagtctttg caaagctgtg tttgcatcac cgaggatcga caaagatgtt
    33301 tcatggcgtc gtccaaattt tgacgcatcg atatcgattt ggataaattc agcagttgga
    33361 ttaaaaaatg cacgtccaaa tgggaagtcg ctaccgacaa ataagatcag atcggcttct
    33421 gccaatgctt catttccggg tttagtagcg acacgtccag caaaaccaag aaagttttca
    33481 taatcatcag gaataattcc ttttgctaga acggaagcga caacaggaac tgaaaaatgt
    33541 tctgagaatt ctttgatttg cggaaatccg tttcgcgttc cttgaccaac ataaagaact
    33601 ggtttttttg ctttttcaag ataaggcaaa gcagctagca aatctttttc ttctggtaat
    33661 atcacacttg ttttgtgagt gtgagcggtg gagaaaggtt gttcgtcaat ttcttcaaaa
    33721 ccaagatcaa cagggatagt cacgatagcc acgcctttat gctcataggc ggctttaatg
    33781 gcttcatcta ctacatgcgg aagactttgt ggtgtcatga ctgtacgatt gtatacgcta
    33841 acatctgcga aaataggatt ttcatttagt tcctggaaag agttatagtt catggatgta
    33901 gaagcaactt gtcctaagaa cgctactaga ggcacatggt ccatctgtgc atcatacaaa
    33961 ccattgatca aatgtgtcgc accaggtcct gcagagccga agacagcgcc gactttcccc
    34021 gttaattttg catctgcagc ggctgcgagt gcgccgactt cttcatgacg aacttgaatg
    34081 tagttgattt cggttttttc ttgatatagc gcatccataa ttgaattgaa agatcctccg
    34141 ggaatgccgt aaatatggtc gataccccag ctttcaagaa cttttaccat tgcgattcct
    34201 gcattgattt ttgacatggt gtttcactcc tttagcaatg atgatacata aattttttgt
    34261 atctagagta tagaactttt tatcgaaaat cccaactaat tcgtcttttc acaaaaatgt
    34321 agtcatgttt ttgggaatat gctagagtag tacatagata gattcaagag aggggaatgg
    34381 catggttgaa tggctattga gacttgaacc ttggcagcaa gcacttgctg ggacagcttt
    34441 tacttatttt atgacagctc ttggtgccgg gttggttttt ttctttaaag aaatcaaaaa
    34501 agaagtgcta aacttgatgt taggatttgc ttctggtgtc atgattgctg caagtttttg
    34561 gtctttgtta gatccggcta ttacaaaagc agaagaaaat ggagatattg cttggctagt
    34621 tgtaagtatt gggtttggtt taggcggtgt gtttttatat atggcagata aaacactgcc
    34681 ccatatgcat tttggaccac aacatgaagc agaaggattg cctacccatt taaaacggac
    34741 gatcttgctt gttttttcta ttacattgca taacattcct gaaggtttag ccgtgggggt
    34801 agcattcggt gcagcagcaa ctgcggataa tccgacagcc gctatattag ccgctgtttc
    34861 ggtggcgcta ggtattggta tccaaaactt cccagaagga gcagctgtat caatcccgtt
    34921 gcgacaagaa ggtctgagtc gtaaaaaggc ctttgtttac ggacaagctt ctggaatcgt
    34981 tgaaccaatt gctggagtga ttggagcgct actagtaacg aaagtggagc tgctgcttcc
    35041 ttatgcactt gcttttgccg caggagcaat gatttatgtc gtggtggaag aattgatccc
    35101 tgaagcacag cagacattgt ccagcaaacg tcattttgca gtttttggcg tcatgagtgg
    35161 atttatcatt atgatgattt tggatgtggc attaggataa ataaaaaaaa tatatatgat
    35221 atatcaaata gggccgcgaa cttatatcgc gaccctattt ttttagtaag ttatatcata
    35281 atgaagtgaa tggtatcata cattaataat agttttttct atgtgtattt cctttgatcc
    35341 agcgaacaag ccagatgata agtgcgattg ggattagaac tttgaccgca aaccataaaa
    35401 gcccgcttag gacactgaca aaaagactga tgacgaagct agctgcaatt agcactaaaa
    35461 gaaccatgaa gatatttaag aacatatttt tttgacgcat acaaaaccct cctcttgttc
    35521 attctttact atagaaaaag tataacaggg attgtttaaa aacacctcca actgaagact
    35581 gatttttact tcatctactt aaatgatcaa acaattgctt tttctctggt ttatcatcta
    35641 aaatagagcg gaaaaggagg agaatatcat gcctaaaaat cgtcttgaag catttacaga
    35701 tgctgtaatc gcgattatca tgactatttt agttttagaa cttcatgaac ctaacggaga
    35761 cacgtgggag gcgctcgctg cattaggtta ccgatttttt atctatattg tcagttttat
    35821 cattttagcg atttattgga acaatcatca tcatttattt caagttgtac ataagataaa
    35881 tggacgggtc ttatgggcga acagtttctt tgtttttgcg ctttcgcttt ttccgtttgc
    35941 aacttcatgg atcagtgagt acatcaatag cctggctcca gaaatgactt atggttttgt
    36001 taccttgacc gctaatattg cgtattatat cttggcaaaa gaacttgtca aagcaaataa
    36061 aggccacgag aaagcattga aggcgatgtt gaataattac aagaaatcgt atctatcgat
    36121 tggtttgaat gtgttaggaa ttgtcttagg gtatttagta gcgccagtag ccgtgctgat
    36181 cgcaaacatc gtgattctag ctgcttggat catcccaagt cgtaccatcg aatcacaata
    36241 tcggtaaaat gatccgtgtt taaaatttaa gagaaaaata tagaaaaaat aaataaacga
    36301 tcaaatatcc gagtgatact agtattcaaa gagggatgca gatggatcaa aaaagaattc
    36361 atgtaggact gattactagt tttgtcacga tgcttattta tttggatcaa ggtcatttga
    36421 cttggacagt agttggtgtc gtaggatttt tgacattatt cacagcaata aaaaaataaa
    36481 catctttatg taatctgatg ttctatctat ttaagaaaag catgtttaca gcagtatgat
    36541 tctgttgtaa acgtgttttt atttgtggaa aatttaattt ttagaaaagt gtatcgaaaa
    36601 atagatagtt agtttttcca cagtggataa cttcgtaaga gataaaaata aaaaattagt
    36661 caaagaaggg cgtatagatt tcttttgata ggagatatac aacagaaatg aataaatatt
    36721 aacgtgtttt caaacagtat aaaacggtgt ggtttttgga ataaaaaaat aacatatctc
    36781 attttacgct tttgttattt tatacttaaa aaataacgac acagaaaata ccgtgtctca
    36841 gatttctcta ctacttctaa aaactactgt ttttttcctt tgaaatgcct tcaaaaagta
    36901 ggatcaggca gaatatactg gcagaatcaa ggagaaggga gcctaaataa ggagaaaaac
    36961 catagaaaat ataaagtaat tacttataaa acaagctttt tatagaaaaa taatatacct
    37021 gagtagggta taaattaaga cggaattcct ttctagattg agatattgac taggaagaat
    37081 gttaagattt taagccttta agctaaaaaa aaaccctttt tgttaaataa ggggaatata
    37141 gcctgtcagt ttcaaactgc aagtcgtcct gctgcaataa tatagtagat tagagatgaa
    37201 aatagatttt tttaaaccaa tgactgaata aaaagaccgt catagataca cattggaatg
    37261 tgtctattac ggtctttttt tacgaacgat tttattgaag acggacagtt cgggtcaaaa
    37321 ataaaaaagc tacgatcaga aataagaata aaatgtatcc caaaataatg gctagacggt
    37381 ctaacttatt tgtcgataga tgtttgttta gaagttgata ggcccataaa cctatcagtc
    37441 ctcctgttgt attagttatc aaatcagtga tgtccgctac gccaataccg aataggaatt
    37501 gaatcaattc tgccaagaag cttacaagga aaataatccc taatttttta gaaaaagaaa
    37561 gtctcttgaa attgacattc aaaagcaccc caaaaggaaa aaagacaatc aagttataag
    37621 tggtctcacg taataccgtc gtattttcaa aagaaaaagt agaaaaaggg acgagattga
    37681 cattgctgta agaataagtg agaaattgtg gaagattaaa tgatagcttg aataaaatca
    37741 accataatag aaagaataaa taaatcccta ataaaaattt tgatacatac cgcatagaca
    37801 tctcctccat ttaaaaagta taccatcgaa aaccgctgaa aaatcataaa aaagtatgaa
    37861 gtttaaggac caacgtagtt atcgtacgaa aattagaagc ttttttttgt tgggaatccg
    37921 gtttctttaa caaagctaag atagcgagtt gcttggaaaa gttgctatct tttttctgtc
    37981 aaaacgactc ggaatgttcg ttttttgttc taatttctcc aagttgttta ctttttgata
    38041 ctaagtttat gaaaaatcaa gaaatagttg ttatactagg taatgctgac aaacgggatt
    38101 ggcatttcat cttggttcag ctttttttcc aattactagg aaggagggat agattgttca
    38161 agacttattt tcgtttcaat aaaatacaag ataatccttt tcgtatcatg aatctgatgc
    38221 tacttatctt tattgtatta tggttaggtt acataaatca tgattttttg atttcaagtt
    38281 tttcatcatt agggatcttt acttttttct attatcaaaa cataccgatg aaatatttgc
    38341 tgaaacgtat gtttctgatc ggttgcggac tgttggttgc tttcgttttg gggatcttat
    38401 cgacttatgt tttatggctt gaaccatttg ccgtagcttt ggttgctttt tccagcagat
    38461 tcgtgttgcg attattccat atttctaaac caggtggctt gttttttgcg atgctttctg
    38521 ccatgggaac gagcatgcag ctgccaatcg ctcaattacc gatcgtctca ctttattttt
    38581 ttatgggtgt cgtttttgcc ctgattgcgg cagtgattac aaaattactg gattcacggc
    38641 ctgagcagac aattgaaaaa gcaactttaa aagaaagatt tcacgaagag cctttagtga
    38701 tcattgattc tgttttctac agcgctgcct tatttctttc cgtttatgtc agtcacggct
    38761 tgaatctgca taatccttat tggttgacct tgtcatgtgc atcgattttg ctagcagaaa
    38821 acttggatgc gatgaagcat cgacaagtcc aatatctgat tggatcgatg ggtgggttat
    38881 gtgtgtcggc attcttgtca tttgtgccgt ttacgcagtt gcagaccatt tttctgatca
    38941 cttttctata tggaatcgca caatttctag ttgctagaaa ttatgcagtt gctaatattt
    39001 ttcttaatcc gatggcgttg atgctatcta cacttattcg tggagcatac ttgatttctt
    39061 tgatcgaata tcgtttttta gggatcgtca taggaagttt catcggttta ggtgttgcgt
    39121 gggtaatgac ggttggtttg caacattatt taacggttgt tcgtcaaaaa ttagaataga
    39181 aggacaaata tatgtgccaa aagaggttat gacaagattt ttgtcacaac ctctaattca
    39241 aggtgttcaa aagccagatt ctcagcatta agtcaaattc acacaaaaat gtggaaagga
    39301 actttcaaaa aaattttata tttattctat caaaaaattt tgtttatgat ggtaactgaa
    39361 taaactttcc tgagatggtc aatgctttcc ttgaaagtct tacagatatt ctttcttcat
    39421 agaaagttta agttttatag ttagtgtaca ataaaagtat gtttatacca tatggtgtcc
    39481 ggataatcag tcatttaaac aatgaggttc aaagatatga aaaggggaaa tttgatgaag
    39541 aaaataagca atgaaatcca aattctggca gaaactttaa ctcttcccaa agtcgttata
    39601 gagcaaatga ttgtacaagc aaaaaacatc cttgatgagg tgtttgagca atatagtcat
    39661 gaactaatgg atcctaataa agcaaaggcg actgcaaaga aaatagacaa agtctatgaa
    39721 gaggaacctt ttgcagcatt agctatttat ctatatgcag cttctcaaag ttggaaaaaa
    39781 atttatcaac cattgaagat tccaagaact atctatttgg caacaatgaa tgcttttact
    39841 agatttattc atgaacattt ccaagtaaca ggaagctatc gctttgaccg tggtttttgg
    39901 atttggcatt acactagtgg cttgatcttt cggattggtg aattggagta cgaaatgaca
    39961 tattttccga aagggtacac ggatctaaga ttagaaggaa agcagtgcct ttctcttcat
    40021 attccttccg atgcagattt atctcagaat aagataagag atagttacga aagtgccatt
    40081 cgtttttttg aactttattt tcctgattac cattaccaag tgatgtacac agatacttgg
    40141 ttactatcac ccaatcttac taaatggttg aaaaaagagt caaaaatctg tctttttgca
    40201 gccgattatc gattattatc agttgatgaa caggacgata gtggagtccc ttggatcttt
    40261 ggacgagtag atgcccaaat acatgattat ccagaaagta cgagtttaca gcgacaagca
    40321 aaagagcaat tgcttgcagg cgagcacatt ggctctggct taggtattct tacttcataa
    40381 gtttagtact tcgaaatagt ttaaaagagc gtgagacaaa agtaaagaac acttttgtct
    40441 cacgctctaa acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctgaa
    40501 attcacaaaa atttgaaaag caattttcgt gaatttcttc ttatttcttg gagttaaacg
    40561 cttctgtccc agcctctttt ttagtgttct atcgaacaca cagtacgttc aataggtaaa
    40621 ctagctataa caatagatat taaagttaac ggacaagagg gcctttttta ggtagctaaa
    40681 acgtaataat gaaaatttat ttccagagat aggagtcaat cagctagtct gatcgactgt
    40741 tttaacaagt tgactttcat tttaactttt gataccattt aaaacacaaa tcgtaattgt
    40801 ttcgatttgt gttttttagc atgactacaa tcaaagaaga aagtgggtcg tccatatgga
    40861 aaaaacagat atctcaagtg cataccgccg cttgaaaagc ccaaatatca aaacacgaaa
    40921 acgtgcgctg aagatcatca aagatgtgaa acggaatagt gggaaaaggt aagaagaagg
    40981 aaacttaatt aaaaaaatag ccgaaaaacg tttttcggct attttcaata atcggttttt
    41041 gtgtaaggtt tccgaaagaa ctgctgttga ttttccattt ttaacatatg ataaattggt
    41101 agaatctttc ttttcaaatt gataccattc cctaattcca gttatatagt taactacaga
    41161 accacaaagc acgtacgttt ataaaagtat tatctgtagt tatttttcaa ttccctttca
    41221 acctcttatt ttgaccagta gtattgatca ctttaccttt taacaccttt gttcgttttt
    41281 gaaacatttt tagtcaagaa tggaaacgta actacataat caaaggtttt gcgaaatatt
    41341 tcatgaaata tttcatgtag aagcgagcaa tacggttgca aataaccatt atcgtttaat
    41401 aagcagttac gaaagctccc aatatctcta acgttcagct cactccattt cttttcttca
    41461 aaaaaatcag tgattcgtat ctctttctat ttgtcgaaaa agttaacttt aaaaagtaac
    41521 gccgaaaaaa tatgcaaaaa aataaaaaag cagttactat tgctagaata acatcaagga
    41581 ataataagtt ttggttttca gataatagtc gataagttgt gtattggaat tttagataca
    41641 gtaataaagt atttttcatg aaattttgtg agaatcacta ttacaagtat ctttaataaa
    41701 attaatggtt aaggaggaac ttaaagtaga atgtaaatga atagttgtag tcagtcgatt
    41761 gtgatactag actcaaagtt gcaggaataa gtttttcaat ttgtgattgg aagataaaaa
    41821 atgaaaaaga agggcttttt tttatacttt gttgattgta gtgtttattt tccctctgtt
    41881 tagccaagta acattttcta tgactcaacc agtttcaagt gaggaacatg ataacctttt
    41941 tcgtgctaca gaagagttta agaaatatca ggaaaatatt gttccggaga ctccattagc
    42001 tagtgagcca attactgata ttgatggaaa ccaaatagga tggtatatac agtacgaagt
    42061 tatggtggta aataatgact caatagtaaa aaatacagta ggcttagagc taacaccgat
    42121 tgaaaaggtg agttcattgt taacgtatat ttatactgat gaaagtgacg agactgagat
    42181 cattttaacg gattactcaa aaattgctac tgataaaaag tatatattgt ggatgtagac
    42241 actagtgaaa tactttatga tatagaaatt gatgaaaatt tactagatgt agcacaagaa
    42301 atcgatcatc aaaagcagga agctattcga tatgctggta gaaaagggaa aagaaaatat
    42361 ttattacgtg aatgtagcaa aagttagaga agatgaaaat gagtggaaag aattcaagag
    42421 tcgctactca attaactcga ctccgacatt tacagtttac agagaaggat cgatagaaaa
    42481 aactgttttt tggactaaag aaagtggaat gtctttagct gaagtagaag agtttttgga
    42541 ttatgttagt atgcaacagt aagggagttc ttattatgaa aaattttgac acatattatg
    42601 ttattgtttt ttcgatatct ttgctgttaa tattactaac tttaatgcag tataaagagt
    42661 atccagagta ttttatttta acttttgtat atttagtaag tagctacaca cttctatata
    42721 aattcagaag ttcttctaga gtttctaaag tttgtttctt aattagctta ttgattctat
    42781 aatatttttg atttatatag gaaattaaaa atattataga atcaacactc agagaacggg
    42841 ttggttttta atagatttaa taagtactga taatgaaatt tctcctggtt gggaaaacga
    42901 agttggttac cctgtagaag aattttttca agattacttt gcggagtatg ccgataggat
    42961 aatgagagat tacgtaacag ataaaactca agaagtcatc aatcaatccc agtcattaaa
    43021 tgaattatct gataaggcga aagaagaagc agttgccatt atttcttcag ggattagtga
    43081 ctatattgat atgagtggtg aaatcaatta tggcgataaa gacaaaattg tacgcatgat
    43141 aaaagctttt atcaaaactt ttgatgtgaa ggcagatctt aagtttaatg atacttacct
    43201 agtaggaaaa ttaattaata tccttgggac agagaaagat acggaaacgt ttatttcctc
    43261 tttgtctatg ttgtttacag ataagcattt ttcaactcag cttggtggag aggaactagt
    43321 ggaaatcttt taaccattac gcccagcatt aataaaagta tatcaaaaaa gtactcctga
    43381 tgatttttaa gattggtttg agaaataatg tgaaaacact atttttaatg ttaattatag
    43441 atagagatga acgcgtcata tggttaaaag aatgaaaaag tcaaagatac actgctatat
    43501 ttcactaagg atatagcagt gtatctttca tgtcgtttca ctggcagttt tttataaaag
    43561 gaggtgtgca tttcagttgc ttttctttgg tagttagttg aatcgtttaa gaattaacgg
    43621 atgtggcaga caggtgctct gtccaaaaac cagtaaaatc tttgatggtt ccatctttat
    43681 ttagctgtgc ctgttcaaat actgttttgt ttttaccgaa tggatcaatt gcaataattg
    43741 ttccgatccc cgcacgtttg gcagcaagta atcctgagta agcatcttcg ataacaagac
    43801 aatcagccgg agctaagctc agtttgtctg ccgctttaag aaaaatatcc ggttgcggtt
    43861 tcccagggaa agagccgtcg tcatagacaa tcttgtccca gtcaaaccag cgggctaaat
    43921 cgaaaatatc aaaataaaaa gcaacattct ctttgacagt agccgtggca atcgttaatg
    43981 gaatctgttg gtcagtcagc tggtcaagag tcgcttcaag cccttttgtc aactgaagct
    44041 cgttttcatt ttgcaagcaa agcatacgat aatagctttc tttttcttct gacaatacgg
    44101 cgatctcaga ggcggtcaaa tgctctgaaa tgaaatgttt caaaatctcc gtattcgtcc
    44161 gaccatgaat attttttaaa atatcctcgt ctgataaacc atcttttgta tgatcatgta
    44221 tcatatgcag ccaagcagct tcatgcagat gagagtccaa aaacattgtt ccgttgaaat
    44281 caaatataat ccctttcata gttacgctcc tatagtggta ttttcggttg aatcagcaat
    44341 ttgcagatcg acatattgtg catagtgctc ttgaacctcc cgcgagatct ggcgatccgt
    44401 aatgagcaga tcgaaatcat gcaaattata aaacacataa aaatcatctc gattgaattt
    44461 tttattatca acgagtagat atttcttacg ggaattattt agagcgatct gctgtgcttc
    44521 tccttcttcg gtactgtaag tagagatcgc ttcgttgtga acgccatttg aactgataaa
    44581 tgcttttgta aactttagtc ttcttaaatt gtcgttggtg atcggtccga caaatgcgcc
    44641 ggtatttttc cggaaatcac cgccaatcag tagaatttct ggtccatctg cttgagcaag
    44701 aatatcaaaa actggataat tatttgtaat gatccgaatt ttcttgttca gtaaatgcgt
    44761 cgccaatagt tcgattgttg tacctggtcc taagaaaatc gtttctccct cgtgaatcaa
    44821 ggaggctgct gtggcagcaa tttctttttt ttcttgaatc tgcagagtgg ctttttcagt
    44881 gtgagaaagt tcttgatcta aagtgtagga aagactttga gcccctccat ggacacgcag
    44941 cagcttgccc gatttttcta attcatctaa atctctgcga acggtcatat cagaaacatc
    45001 taattgattg atgatttcat taacggtaag gattcctttt ttattgacca tttctacgat
    45061 agtaagcaat ctttcttttt tcaacattgt cttcacctct aatttaagga taatctatca
    45121 tataaacgga caacagtcaa tctaattcga acaaaagtaa acatttaggg tggtttttat
    45181 gtttgttaca atagatttta ttgctgtttt ctggttttta tgattatttg tgtttgtttt
    45241 tgttgacaaa tgttttggat gcgtttacaa tgcaatcagt tagaaagagc gaaaactgat
    45301 tatagatttg aggagagatg tacatgctta aattaccaga agattttatt tttggcggag
    45361 ccacagcagc ctatcaggtt gaaggagcca ctaaggaagg tggcaaaggc gctgttgctt
    45421 gggatgactt tttagaggaa caagggcgat tcagtcccga tccggcaagt gatttttatc
    45481 atcaatatgc aaaggacatt gaattgtgtg aacgttttgg tgtaaatggt ctaagattat
    45541 ccattgcttg gagccgcatt tttcctgatg gagctgggaa accaaatcca gaaggaatcg
    45601 ctttttatca tcgtgtgttc gaagaatgta agaaaagaaa cgtaacgccg tttgtgacgt
    45661 tgcatcattt tgatacccct aaacgtttgt ttgaccatgg agattttttg aatcgagaaa
    45721 caatagaagc atttgtttcc tatgccattt tttgttttca tgaattcaaa gaagtcaagg
    45781 tgtggagtac ctttaatgaa atctatccag ttgcaaccaa tcaatatttg ttaggtgttt
    45841 tcccaccagg aatcaaatat gattttacaa agatcgtcgc ctgtcttcat aatatgatgg
    45901 ttgctcatgc ccgtgtagtg aactatttca aagaaaacga acttccgggt gaaattggtg
    45961 tagttcactc attagagacg aaatatgcgg caacagacgc gccggaagat aagcatgctg
    46021 cctttttaga cgatgcattg tcgatccgtt tcttattaga tgctacctat ttaggctatt
    46081 attcaactga aaccttgact gctcttgatg agatatgtga agcaaatcag gccagctatc
    46141 attttcctga agaagatttc gttgaattga aaaaagcatc cacgcgtaat gactacttag
    46201 ggatcaatca ctaccaatgc cattttgtca aagcttacga tggagaaaat gcaatccatc
    46261 ataacggtac gggtgaaaaa gggacctctg tttataaagt gaagggaatc ggagaacgta
    46321 tttataaaga aggaattcct cgaactgatt gggactggct gatttatcca gaaggtctat
    46381 atgacttgtt gctgcgaatt aaaagcgatt acccacatta caacaaaatc tatatcactg
    46441 agaacgggat ggggtataaa gatcagtttg aagatggcat tattatggat cagccgagaa
    46501 tcgactattt gagagtctat ttggaatcct taagcaaggc gataacagcc ggggtaaatg
    46561 tgaaggggta ttttttgtgg tcgcttatgg atcttttctc atggacaaat gggtataaca
    46621 aaaggtatgg cttgttttat gttgattttg aaacccagaa gcgttaccca aaagaatcag
    46681 cttactggta caagttggtc agtgaaacca aaacgattat ttaataagtg ataatggagg
    46741 aagaaaagat gaataaagag gaattacaaa tgcttggttt tgagatcgtt gcatattcag
    46801 gcgacgctcg cagtacatta ttgaaattat tgaaagaagt aagacaagga aactttgaac
    46861 atgttgattc ggcgttgaaa gaagccgacg aaaatttaac ccttgcacat aattcgcaaa
    46921 caaaaatttt agcggaagaa gcatctggga aagagatgga gatgggattc atttttatcc
    46981 atgggcagga tcatttaatg accactttat tgctgagaga tctgattcaa gactttattg
    47041 tactgtacag acagaatcaa ggataggaga agaacgctat ggatggaatc attaaacaaa
    47101 tcgaaaaagg gaaaccattt tttgaaaaaa tctcacgtaa tagttattta ggagccgttc
    47161 gtgacggatt tttaacagcg atgccagcta ttttattttc aagcattttc attttgattg
    47221 ctgcggttcc tgagattttt ggttaccaat ggcctgaatc tgtctccaca tggctatgga
    47281 aagtctataa ttattcgatg ggtgttgtag ggttactcgt ttcagcaacc actgctcgct
    47341 gcttggctga ttcgatgaat cgtcgcttac cgaaaaacaa agtaatcaac accacctctg
    47401 tgatgctggc ctctgtggta agtttcctgt tgttaagcgt ctctccgatt gaaggtggat
    47461 tttcaacgga atatatgggg acaaagggac tactggcttc ctttgtcgct gcatttttaa
    47521 cagttaattt atataagttt tgtgtgctga aagatattac cattaaaatg cctaaagaag
    47581 ttcctggaac gatttcgcaa accttccgag atatttttcc tttctctttt tcagtatttg
    47641 cggccgtttt aattgattta ggcattcgac aaatcttcca aatctcattt gcagaagcaa
    47701 tcattacggt gctgcagccg ctatttacag cagctgacgg gtacttagga atcgctatta
    47761 tctggggagc gatggcgctg ttttggtttg tcggtgttca tggaccgtcg atcgtggagc
    47821 cggcaattgc ggcaattatc tatgccaatg tggaaaccaa tctgcaattg ttcaattccg
    47881 gtgaacaagc ttctaaagta ctgacggtgg gtttagggaa ttttgtagga actatgggag
    47941 gaactggggc aacattggtt gttcctttta tcttcctact ctttgctaag tctaagcagt
    48001 tgaaggcagt tgggaaagct tcctttattc cagtaagttt cgctgtcaac gaaccattgc
    48061 tatttgcggc acccatgatt ttgaaccctt atttttttat tccatttttg ttaacacctg
    48121 ttgtaaacgt ttgcctgttc aagttttttg tcgatgtatt gggcatgaac agctttatgt
    48181 acgttttgcc ttgggcaact ccagcaccga tcggtttggt tctaggaacg ggcatgggta
    48241 tcttagcttt tgttctagca gcggttctaa tcgtcgttga cttcctgatc tatctaccat
    48301 tttgcaaagc atacgatgct gtcttagtag agaaagaagc acaaaaagca gaggtgatcg
    48361 caaccgagga aggtgcttct gccgatgtac gtgaggaagt acctgtggca gcgagtcaag
    48421 ttatcagcga tgcaaataaa gaaatcaatg tgttggtact ttgtgctggc gcagggacaa
    48481 gtgcgatgtt agctaatgct ttaaaaaaag gtgcatctga atcgaaagca ccgatcagtg
    48541 caatggcggg tgcttatggt tctcattacg aaatgctgca ggattttgat atggtggtct
    48601 tagcaccgca agtcaattct tactatgatg atatcaaaga agacaccgat cgcttaggaa
    48661 tcaagctggt tgcgacaaaa ggagcagaat atatcggatt aacgagagat cctgaaaaag
    48721 ctgttcagtt tattctgaac caatttcaat aaaggaggag ccataatgaa aatgggaatt
    48781 tggttgcgta aagctgtttt atttgcagct gtgttagggg ctttgggggc tgtttcaaaa
    48841 actgttgaag catctgccag cgaatttatt cgcggagcag atatttcgat cctgtcagat
    48901 atggaaaaat ctggtgcaaa atattatgaa gacgatattt caaaagatgc cttagagatt
    48961 ttaaaaaata atggtgtcaa ctatgttcga ctgcgtttgt ggcaggatcc ttataatagt
    49021 aatggagaaa gttatggagc agggacaaat gatctggaaa cgacgattga ccttgcaaaa
    49081 cgagcaaaaa atctgggact taaggtgctg ctggattttc actacagtga tttttgggtt
    49141 gatcctggga aacagaatct tcctaaagca tggcaaggtc tgacctttga agaaatgaat
    49201 acggcattgt acgactatac aaagaacgtt ctgtcggaaa tgaagcagct ggacgtttat
    49261 cctgatatgg ttcagatcgg caatgaactg aatagcggaa tgctctggcc ttatggcaag
    49321 tcttggggag aaggcggggg agaatttgat cgattggctg cttttttgaa gtctggtatc
    49381 caagctgttc gagacactca acctaaaaca actccagtaa tgctccactt agctgatggt
    49441 ggcgatacag gagcatttac ttggtggttt gatgaaatca cgagtcgagg tgtgtcattt
    49501 gatttaattg gagtgtcgta ttatccgtat tggcacggtt caatgaatga acttcaaacc
    49561 aatatgaatg cgatcagcca acggtatggt aaagaagtga tcgtagttga aacagcttat
    49621 gggcatacaa cagcgaatgc cgatactatg ccaaatgctt ttggtgaagc cgaagcagct
    49681 gcggggggat atgaaccaac accgacagga caagcagagt atttgctgga tcttgccgat
    49741 cggattcagg cagtaccgaa taatcgcggg gcgggcttct tctattggga acctctttgg
    49801 tacaacggaa atgtgagttg ggcaacacaa gcaggtatga attatctcag tgttcaatcc
    49861 actatgggaa acgaatggga caaccaagcg atgtttgatt ttgctggaaa cgccttgcca
    49921 agcttgcgtg cgtttaaaca agcaggggcg caaataaatc tagttaaaaa tgcaagtttc
    49981 gaaagcgatg gaccaacgac cagtccttcc aattggcaaa cctggtttca acaaggaacc
    50041 gctaagggta cgatcaaaac ggaagcgggc actttttttg gggactacaa actaactttt
    50101 tggcaggatc aagcatacga ggcatcagct tatcaaaatg ttagtggcat aagcaaagga
    50161 acttacacat tgagtgccta tgtaatgtct gggggagagt ttgatactaa tcagttatat
    50221 atcaaaaatt atggtggagc ggaactaaat actgcggttg ttaaaacaag tgaatggaca
    50281 aaaattacaa tcaaagacat tccaattaca acaggtgttt gtgaaattgg ggtttatagc
    50341 aaggcttcag gaaatgcttg gacgaacgtt gattttgttt cattggtgaa acaatagact
    50401 gcggatcgtt tcgattcaag atcggaggtt cccttcagcc acatcgttag cgtagaaggc
    50461 aggaatcgaa cctgcacctc gcctttgcca aaaataacca gaaacgattt ccagtcattt
    50521 ttaccaaaac gagtaaagca ccagacttca tctacacttt gtattatgct aaagagagtt
    50581 caacgatttc gtaagaagca atgaaaaaat tgcaaaaagt tgtgcagata acataaagtt
    50641 tgtttaagaa agggtaacct tagaattccg tcgtgaatat gatttgagca cttagatgga
    50701 tagaaaaaag ttctcggaaa acagttcgtt tttcgagaac ttctttttat gataagaatg
    50761 aaacaaatta acttatatta tagtctcttt tggtagggaa ccatcttatt tttaatgaaa
    50821 atcaagcatt ttagctattg aagaatgttg atttataggg attccccctc catattatgt
    50881 tggctcttta ttcccactct gttttcaacg taaagtgtat aaaacagaat gcgatactat
    50941 caagggagtt aaaacaatat acagaacagt aaaacactat aaataaaaat aaaagtgcaa
    51001 taaaagtgca atttttgcac ctaatcatac tctgtttata tatgaaaact agattctgaa
    51061 tccaatattt ggttaacgag aggcgttcga atttgaacgt cttttatata ttactttcaa
    51121 ataaatatga ggtagaatac tatctatttt ctttttaacc caattgttat aatggagagt
    51181 gtaaaatatt ttgtgtaaat agaaaaaagg aagtcccttc tgtagaatag agttaccaca
    51241 acacattcac agaagagagg acttccctat gaacgatttt actacagaaa ttctaaagac
    51301 tctagcgaac aaaggcgatt tgaatgaatt attccgtgtc catttggaga aagcagtcaa
    51361 tacgcttctc aaaacggagt taacggcttt cctagattac gaaaagtatg atcgcattgg
    51421 ttttaacacg ggtaattctc gtaacggctc ctatgaccgt acggtcaaga ccgagtatgg
    51481 ggaacttcat ctccagattc cgcgcgaccg caatggtgag ttcaagcaac agactgttcc
    51541 tgcttataga cggacgaatg acacgttaga ggagaccgtc attcacctct tccgaaaagg
    51601 tattaccatg tcggaaatcg cagacttgat tgagaaaatg tatgggcatt actacacgcc
    51661 ccaaaccatg tccaatataa caaaatcatt tacagaagag gtaacggcgt ttaatgggcg
//
LOCUS       DAFTHM010000008        51244 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFTHM010000008 DAFTHM010000000
VERSION     DAFTHM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.008"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            290..1135
                     /locus_tag="L7C88_000511"
     CDS             290..1135
                     /locus_tag="L7C88_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBP9557368.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="L7C88_000512"
     CDS             1416..2636
                     /locus_tag="L7C88_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBP9557369.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="L7C88_000513"
     CDS             2633..5353
                     /locus_tag="L7C88_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9557370.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="L7C88_000514"
     CDS             5337..6281
                     /locus_tag="L7C88_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBP9557371.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6350..7360)
                     /locus_tag="L7C88_000515"
     CDS             complement(6350..7360)
                     /locus_tag="L7C88_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBP9557372.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7540..7884)
                     /locus_tag="L7C88_000516"
     CDS             complement(7540..7884)
                     /locus_tag="L7C88_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBP9557373.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7877..8311)
                     /locus_tag="L7C88_000517"
     CDS             complement(7877..8311)
                     /locus_tag="L7C88_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBP9557374.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8449..9186
                     /locus_tag="L7C88_000518"
     CDS             8449..9186
                     /locus_tag="L7C88_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557375.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9179..10390
                     /locus_tag="L7C88_000519"
     CDS             9179..10390
                     /locus_tag="L7C88_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557376.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10594..11376
                     /locus_tag="L7C88_000520"
     CDS             10594..11376
                     /locus_tag="L7C88_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBP9557377.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11446..12108
                     /gene="trmB"
                     /locus_tag="L7C88_000521"
     CDS             11446..12108
                     /gene="trmB"
                     /locus_tag="L7C88_000521"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBP9557378.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12206..13960)
                     /gene="ade"
                     /locus_tag="L7C88_000522"
     CDS             complement(12206..13960)
                     /gene="ade"
                     /locus_tag="L7C88_000522"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBP9557379.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14092..15021
                     /gene="tadA"
                     /locus_tag="L7C88_000523"
     CDS             14092..15021
                     /gene="tadA"
                     /locus_tag="L7C88_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBP9557380.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGTVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14978..16027
                     /locus_tag="L7C88_000524"
     CDS             14978..16027
                     /locus_tag="L7C88_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBP9557381.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16024..16302
                     /locus_tag="L7C88_000525"
     CDS             16024..16302
                     /locus_tag="L7C88_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBP9557382.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16277..16747
                     /locus_tag="L7C88_000526"
     CDS             16277..16747
                     /locus_tag="L7C88_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBP9557383.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16764..17066
                     /locus_tag="L7C88_000527"
     CDS             16764..17066
                     /locus_tag="L7C88_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557384.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17083..17454
                     /locus_tag="L7C88_000528"
     CDS             17083..17454
                     /locus_tag="L7C88_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBP9557385.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17426..17785
                     /locus_tag="L7C88_000529"
     CDS             17426..17785
                     /locus_tag="L7C88_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557386.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17957..18964
                     /locus_tag="L7C88_000530"
     CDS             17957..18964
                     /locus_tag="L7C88_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBP9557387.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18989..20173
                     /locus_tag="L7C88_000531"
     CDS             18989..20173
                     /locus_tag="L7C88_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBP9557388.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20610..22193)
                     /locus_tag="L7C88_000532"
     CDS             complement(20610..22193)
                     /locus_tag="L7C88_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBP9557389.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVDINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHCQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22771..22914)
                     /locus_tag="L7C88_000533"
     CDS             complement(22771..22914)
                     /locus_tag="L7C88_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBP9557390.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23136..23615)
                     /locus_tag="L7C88_000534"
     CDS             complement(23136..23615)
                     /locus_tag="L7C88_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBP9557391.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23688..23972)
                     /locus_tag="L7C88_000535"
     CDS             complement(23688..23972)
                     /locus_tag="L7C88_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557392.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24050..24244)
                     /gene="ssrS"
                     /locus_tag="L7C88_000536"
     ncRNA           complement(24050..24244)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="L7C88_000536"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24316..25602)
                     /locus_tag="L7C88_000537"
     CDS             complement(24316..25602)
                     /locus_tag="L7C88_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBP9557393.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25740..26411
                     /locus_tag="L7C88_000538"
     CDS             25740..26411
                     /locus_tag="L7C88_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBP9557394.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26377..26865
                     /locus_tag="L7C88_000539"
     CDS             26377..26865
                     /locus_tag="L7C88_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBP9557395.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26878..27825
                     /gene="prmA"
                     /locus_tag="L7C88_000540"
     CDS             26878..27825
                     /gene="prmA"
                     /locus_tag="L7C88_000540"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBP9557396.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27826..28590
                     /locus_tag="L7C88_000541"
     CDS             27826..28590
                     /locus_tag="L7C88_000541"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBP9557397.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28823..31036
                     /locus_tag="L7C88_000542"
     CDS             28823..31036
                     /locus_tag="L7C88_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBP9557398.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31047..31493
                     /locus_tag="L7C88_000543"
     CDS             31047..31493
                     /locus_tag="L7C88_000543"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBP9557399.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31664..32923
                     /locus_tag="L7C88_000544"
     CDS             31664..32923
                     /locus_tag="L7C88_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBP9557400.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33012..33959)
                     /locus_tag="L7C88_000545"
     CDS             complement(33012..33959)
                     /locus_tag="L7C88_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBP9557401.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34353..35645
                     /locus_tag="L7C88_000546"
     CDS             34353..35645
                     /locus_tag="L7C88_000546"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBP9557402.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35660..37429
                     /gene="aspS"
                     /locus_tag="L7C88_000547"
     CDS             35660..37429
                     /gene="aspS"
                     /locus_tag="L7C88_000547"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBP9557403.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37538..38413
                     /locus_tag="L7C88_000548"
     CDS             37538..38413
                     /locus_tag="L7C88_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBP9557404.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38679..40562
                     /locus_tag="L7C88_000549"
     CDS             38679..40562
                     /locus_tag="L7C88_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBP9557405.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40637..40921)
                     /locus_tag="L7C88_000550"
     CDS             complement(40637..40921)
                     /locus_tag="L7C88_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBP9557406.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40911..41645)
                     /locus_tag="L7C88_000551"
     CDS             complement(40911..41645)
                     /locus_tag="L7C88_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBP9557407.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41774..42397
                     /locus_tag="L7C88_000552"
     CDS             41774..42397
                     /locus_tag="L7C88_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBP9557408.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42589..43710
                     /locus_tag="L7C88_000553"
     CDS             42589..43710
                     /locus_tag="L7C88_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBP9557409.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43717..46845
                     /locus_tag="L7C88_000554"
     CDS             43717..46845
                     /locus_tag="L7C88_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBP9557410.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANERIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46864..50058
                     /locus_tag="L7C88_000555"
     CDS             46864..50058
                     /locus_tag="L7C88_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBP9557411.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50204..50911)
                     /locus_tag="L7C88_000556"
     CDS             complement(50204..50911)
                     /locus_tag="L7C88_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBP9557412.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16772 a         8945 c        10635 g        14892 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 ttgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttcttt tattttgatg
     6361 aatcagttgt ttcttcagtt gaagattctt ttgttgaatc agttgatttt gtgtcagaac
     6421 tctttgttga agctgtagtt tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg
     6481 cactcaacac attttcaaag gcatcatctt tgatttttac atttgcatct tttaattctt
     6541 caccgattac tttagttgtg aatgcattgt cacttagttt agtttcagta gcgatatctt
     6601 ttagttgatc tttgtattta tccatgtcat tgcctttatt ttggtttttc accattttga
     6661 caacgtagta ttctgtcgca taagaagtag gatttgttgt agtaataaca tcggagatct
     6721 caccgtcttt caatttgaaa gctgcttctt ttacttctgc aggaatagtt gttgtcgttg
     6781 agtcgaattt aactttaccg ccatcttctt ttgtctctgt atcagttgat ttgtctttgg
     6841 ctaatttaga gaaatcatct ccatcatccg ctgatttttt cacatctttt gcttcatctt
     6901 cacttgataa tttgatgatt tgtgcttcta cttctggatg gaaagatttc caagcagttt
     6961 tcaaatcgtc atctgtaata tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt
     7021 tacgaatata ttctttataa gtatctttcg tatatccagc agcttctaat tgtgattcaa
     7081 aagtatcacc taatgatttc gcttgtttgt cgtattctgc atccacttgc ttatcggtta
     7141 ctttatcgcc atatttgtta ttgaatactt tataaatgat catccgttgt actaaggatt
     7201 ggttcgatga ttcaagtttt gcttcatcat agaaatcaga tacagtgatc gttccgcctt
     7261 tcatcgttgc gatatcttta ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca
     7321 acgcactagt agctgccaaa ataattgatt tttttttcat taaaatttgc actcctgtaa
     7381 ttagttatta tttttatata ttaactatac catatcccat ttcctttaaa aacgttgtcg
     7441 tggtagtttc aaacaaaatt caaaatttca tcacattcct aggaaatacg caaacttttc
     7501 tcacttatat agttaaatct gttgagaaaa taatcattat tatatttgtt caggatactc
     7561 tggcagatca gcttttagtt tttctacttg ttcattgatt tgtgtgatac gtggttcggc
     7621 ttggaattta aaatcttcga tatctttttt gattgcttct tggaaagcag gaatcacaga
     7681 ttcagctgtt tcttttgttt cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa
     7741 atcatttgtc agagttgttg cttcttccaa ttcttcgatc agtttctttc ttgtttcatt
     7801 cccgctcctg ggcgccaata acagacctcc gacagtgcca gcagcagctc caaataacag
     7861 tcctttgaaa aagtttttaa tcatcgcagg acacctgctt tacgattgtt tcttgaatag
     7921 cttttagttc ttccgatcca taactatctt gatgattgac aaagtgaata gaaaaatcat
     7981 cctctttgct gtagcgaggg actaaatgga tatgtgaatg aaaaacagat tgataggcta
     8041 gttcacggtt gttattcaag atattaagac ctttcatttc tggaaaagct ttttccaatg
     8101 cttgagcaat cttaggcaca cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa
     8161 aaatatctgc tacatgacgt ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga
     8221 tgtctaaaaa agcatagacc ttgtcgtctt catatatttt atagcttggg atttcttgat
     8281 tgatgatttt gcaaaaaata cagttttcca tataaaacat cctttctata aagaataaat
     8341 acttcagctt aactttacca taagttaaag ctattgtaag gaaaaaaaca aaataccgtc
     8401 attttcttcg tggtataata aataaaaata aatggcggag gaaaaagaat gagtttaatt
     8461 atcgatcatg tcacaggggg gtacggacat ctccctgtgt taaaagatat cagtttcgat
     8521 gtacagcctg gagagatagt agggttgatt ggactgaacg gagcagggaa aagtacgacc
     8581 atcaagcaca ttatcggtct gctggaagct tcaaaaggaa cgatagaaat caatcatcta
     8641 tccttaaaga aaaatacgga agaatatcgc aaacaaattg ggtatattcc agagactcct
     8701 tctttatatg aagaattgac attgagagaa catatcgaag tcactgcgat ggcctacgat
     8761 atacctatgg atatagcaat gaaaagagca gaaaagttgt tggagacttt tcggttatct
     8821 aatcgtcttg actggttccc agctaatttt tcaaagggaa tgaaacagaa agtgatgatc
     8881 ttatgcgcct ttttgatcga gccttcttta tatatcatcg acgaaccatt tttaggcttg
     8941 gatccactag ctatcaatgc attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc
     9001 ggtattttga tgtctacgca tattttagct actgcagaaa aatattgtga tcgttttgtg
     9061 gtcttacata acggagagat acgagcagac ggttctcttg agatgttgag aaaagaattt
     9121 cagctgccgg attcttcttt ggacgaaatc tatattgctt taacaaagga gcaggcacat
     9181 gagtagtttt tttcaaaaac gtttagcaag acatcaaaag aaaatgatga aatatatgcg
     9241 ttatgtattg aacgatcatt ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt
     9301 atattattct aattggttga aaaccctgca gccaccgttt gcaattggag ggctcataat
     9361 ctctgtattt tggatgctct gtttattcgt gggtaagatg gctacttttg cagaggcagc
     9421 agatattgtt tttttacttc ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt
     9481 tcgctattct tgcatttttc cgttgatctt tttgatattg gcatgcggat tggccatgcc
     9541 attagtggtg gttagtacgg agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt
     9601 atggagtttg aaattcagtc atctgcaaat caagagagca gaattgtttc gactagatca
     9661 acaagttatt cgttattgga aattaggctg gtttttttct tctctgatct ttttgtttct
     9721 atcattttat tggctaatat gggcaggaat agcaggtgca ttagtacagg caagtctata
     9781 ttactggttt ttgtggaagc aacaagaaaa aggattggat tgggagaaaa tggtgcatgt
     9841 agaagaacat aggttgcatc agatctatca atttatcaat ttattcacag atgttcctga
     9901 aattacggca aagatcaaaa gaagacgcta tttggatcct atattgactc atattaaaag
     9961 agaatcaaaa aacacttatc tttacttgtt tgcaagaaga ttggcaagag gttctgattt
    10021 tagtggtctt tatttccgat tagtaattat aggtgggtta ttgattgccg gagtagtcga
    10081 cttttatttt agtctgatta tcggtttctt atttttatat ttgatcggtt tccaactgtt
    10141 acctttagcg aaccagttcc gctatatggt tctcgttcag ctttatccaa tccataagaa
    10201 tcagaagaag caggcgattc agtatctact cacatgggta ttaattatcg cgtcggttat
    10261 ttttggtttg attgctgcag tcgtattaga tgggcagcag cgatgggttc cgctagcggc
    10321 ttatttgatt gttactatgc tctttgttaa actatatgta ccaactcgtt tgaagaagat
    10381 gtcagactga aaacaaagct gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca
    10441 gtaagaatgc tgttcgttct attttttttg agaaaagctg gttttttgaa tggcaattaa
    10501 atgaaaaaga acgtatatgt gcttgacgtg tagtgttcag gcgactagaa taataagtac
    10561 tgcaaaacaa agagtaagag gacgggagaa tgcatgatgg agtttcagtt agaccaagag
    10621 tggcggttac gtcccatcaa aggcgacaca ggaaaaacat acataggcat gcgtgatgag
    10681 gacaaagtct ttattaaacg aaacacgact ccgatgttgg ctgctctttc aagggaagga
    10741 attacaccaa aacttgtttg gacaaaacga acggggaatg gcgatacttt gacagcacaa
    10801 gagtggctgg aaggtcgctt gctgactcct aatgagattg gtcaaagaaa cgacgtgatt
    10861 gatgttttgt accatttaca tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt
    10921 ggtcgtgtca tgacgccgga gaagatgctg caaaaatatg aaaaagaatt accggaagaa
    10981 ctccagaaaa atcaatttct gcaaattgtc catcgttttc ttcgtgagca gatcccgtca
    11041 atagataagg aaaacttatc agtagtacac ggagatgtaa accatcgtaa ttggttagta
    11101 tgtaaaaatt atttatatct agtcgattgg gattcaatca tgtttgcaga ccctgcggtg
    11161 gatattgcaa cgattttagg aaattatgtg ccactgtcta gctggaatca gtggctgatc
    11221 agttatggca tacgcccgac tgacgaaatg cttgaaaaat ttcattggta tgcggccatg
    11281 aatttgctcc aagaaatcac cagatattgc aaacgtgaag atcatcgacg gatgaacgaa
    11341 gaaattttac aattaaaacg aattttcagt ggctgaggtt tggcccaaac tctgcggaga
    11401 tttggccaga cctttttaat tagaggaaag gaatggagat aaataatgcg tgtccgaaat
    11461 cgtccgggag cagcggaaat gttagcggct cacccgaatt ttgtaattag tgatccaaca
    11521 ttgtggaagg gaaaatggaa tgaattgttt gaaaacgatc atccaatcca cattgagatt
    11581 ggtatgggga aaggccagtt catcactgga atggcaaaag cccatcctga aatcaattat
    11641 attggagtag aaatgcaggt cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa
    11701 ccgcttccta acctgaaact tctacatgtg gatggatcag cgttgacaga gtatttcgct
    11761 gacagcgaag tagatcaaat ctatctgaat ttttccgatc catggccaaa aaaacgtcat
    11821 gaaaaacggc gattgacata taagactttt cttgctgtag atgaacagat tcttcgtcca
    11881 aatggagaaa tccatttcaa aacagataat caaggattgt ttgagtattc tctggcaagt
    11941 ttttctcaat atggcatgat cctcaaacag gtatggttag atttacatca aagtcaattt
    12001 gaaggcaata ttatgacgga gtatgaagaa aaattttctt caaaaggtca acgtatttat
    12061 cgagtagaag ctcaatttca agataagacc aaaaagaaaa gtctgtgaaa ctaactttct
    12121 gctttcataa aaacattaat atccataaat aaatctcaga aaatgaacat tacagatgta
    12181 atgtattttc tgggatttat ttgatttaaa atgtatttat ttcatcggtt tttccacaag
    12241 gtggaatcaa ttggaagcga gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg
    12301 gtatgacaga taatgttaag aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc
    12361 ctagttgatg tgctttagtt attaattcat tcaactgttc atagacgatc gaaaaaggtt
    12421 cctgtgtcat gattccgcct ataggaagag aaacacaagc tatttcctgc tgtttgttga
    12481 caacggtcat cccgccacct ttttgaatca aaagattagc agcatacagc atatcctcgt
    12541 cgtttgtccc aacgacaact agattatgcg agtcatgggc aatcgttgtc gctatcgctc
    12601 cttgtttcag ctgaaatcct ttcactatgc ctaatccaat gtttcccgtt tgatggtgac
    12661 gctcgatcac cgcaatcttt aattggtctt tttcgattga aggaatgaat cgttcgcctt
    12721 gtcggtccac tttttctacc aaatctttag tcactagact attcgggata atttcgatca
    12781 catgggcttg tgaagaagaa agaagcagct ctaacgaatg tggatttaat ggttgagcgt
    12841 ttagttttgg cagacaacac gtatatgaat ttgaatgatc agcaaataaa tggtcttgga
    12901 gttgcccaga ttgaacaact aatgttccct tatagaaaac ttcatgaatt ggcagcttgg
    12961 taagatcgtc tgttaagaag aaatcagctt gatacccagg ggcaatcgca cctagtgttt
    13021 tcaaatcaaa acattctgct gcattcaatg ttgccatctg aatggcttgt aatggatcga
    13081 ttccaagtgc aatagcttga cggacgatat gatcgattga tccttctttt actaaatcat
    13141 tgatcagttt atcatcggtg acaaagaagc atcttcttga attttcaggt gtgatcgccg
    13201 gtagtagcga tgccagatct tttgcaacgg tcccttctcg aaccattaaa tacataccaa
    13261 gatccaaacg ttctttagct tcttttgcag ttgtagcttc atgatccgtc cgaatacctg
    13321 ctgcaggata aacatttaac tcttccatgc cgataccagc tgcatgcccg tcaatttttt
    13381 tcttatgctg gtgcatcaat tggatctttt ctaggatgtc tgtttcatta tttgctactg
    13441 cttgatagtt catgacttca gctaagccta aaacttcggg tttttgtaaa aaaggggcta
    13501 atttttttgc atttaaattt gcaccattgg tctcaaaagg ggttacaggt acacaagaag
    13561 gtagcataaa aaagatattc atgagtgttt gtcttgcatc ttctatcata aactcaagac
    13621 ctgtactccc agcaatgttt cctatttcat ggggatctgt cactacagta gtaactccat
    13681 gaagcaagga tacttttgaa aattcgcttg gtgataaaag tgagctttcg atatgcacat
    13741 ggccatcgat gaatcctggc actagatatt gcccattagc attatgtacg ctttttcctt
    13801 cgtattcacc gattcctacg atcattcctt cgcagattgc tacatctttt tccatgattt
    13861 ctttcgtaaa gacgttgacg atcttagcat gcttgatcac taggtcagca ggcttttttt
    13921 tacttgctac ttcgatatat ttccttaatg ttgtttccaa tggagtgcct cccaagataa
    13981 atttttataa gtataacata aattcggctt ttgccaatat ttttttgtaa attcatttta
    14041 tttgaaacaa aaagatcaaa aagacgtatg ttttttgtgg aggggagaat aatggaaata
    14101 aaacgattat cggatcaaat gataagtgaa agttttgcca aacatgccca agacgtatat
    14161 atattgccag cttcagaagt attttacatc tattttcgct atggaaaaaa acgaacattc
    14221 tggaagaaag tctcttcggc agatggacag caactgatct caagatttaa gtatttggga
    14281 cagatggata tcggagaaaa aagaaaagct cagttaggtg catttactta ttctttagaa
    14341 aaacaggaag ttcgtctgcg gttgtcttct gtaggagatt accttcaacg agagagttta
    14401 gtgattcggc tattatacgg tacttttgaa acaccccatc gttgctttag ttctcgagat
    14461 tttgcaacta ttttacagaa aaccgtcaga cgtggattat accttttcag cgggacagtc
    14521 ggatcaggca agacttctct aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt
    14581 actatcgaag atcctgtaga gatagaagaa ccgttttttc tgcagctaca gatcaatccg
    14641 aaaatagcac agacttatga tacacttttg aaactcgcat tacggcatcg tccagacttg
    14701 ctaatcattg gcgagataag agatgaatca actgcacatg ctgcggtaag agcagcacta
    14761 acagggcacc gggtttttgc aaccgtacat gcacgcaatc ttgaaggtac attggtcaga
    14821 atccatgaac tgacaaagaa aaaagaagag ctatctgaat gtttagctgg tgtcatttat
    14881 caagaacttt tggaagatgc caatcaccat ccttctgttt tatggagtta tcaatttatg
    14941 gaggaagaat cagtaaaaaa atcatgggag gaaagttatg aagaagctca ggaaaatatt
    15001 tggcagtcag aactattcta aaggattaac aagaagccag caaaaccagt ttgcacaaac
    15061 catgggagaa ctgcttttat ctggttttag tctgcaagaa tccctttatt tattactcac
    15121 gatccgttcg tttccacctg ttattttggc aaatatccaa catcagctaa aggaagggca
    15181 agcgtttagt gaggtacttt cgcaaatagg atatggagca gagcaactgg tacagatcga
    15241 gttagctgaa cgtcatggga atctgccgac aactttgttg gaaattgcca aacagtttcg
    15301 gcttgttgaa ggatttcgca atgatttgaa aaagctgctt gcatatccga tgctattgct
    15361 cacctttttg ctaggtatct tgtttagtat gcggttgttc gttttgcctc agcttattgg
    15421 ttcaggaatg gtcatgcaag agcattgggg tattcagctg atacaagtct ttcattggta
    15481 tgttctacta ttcatcctag cggttactct attggcttta ctagtaaggt atcgtctgat
    15541 gaagttgtct cctgttgatc agagtgaatg gataagcaga caattattga ttggaccgat
    15601 atattccttg tatcaatcgg cttatttgtc actagagatt ggaaagcttt ttcatgaagg
    15661 tttcgaatta aggcaaatca tagtctgctt aaaggaaacg aaacaagaaa gtctgattca
    15721 gcatcttgcc tctaagttga ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt
    15781 ccagaattat cgttttctat cagaagaatt cagtaaaatt gttttacagg gagaggcaaa
    15841 gggaagttta ggtaaagaac tgatttttta cagcgaatgg acaagaaaac agcttttcaa
    15901 acgtcttcat cactggatgc attttattca gccaatcatt tttttgggcg tagcggcttt
    15961 gattttatta gtttatgccg ctgttttatt acctgtttac ggaagcatag aggaggtttt
    16021 gccatgaaaa agagaaaaat atcttattat agcggtttta cattgatcga aatgctaatc
    16081 gtcttactga tcatcagtgt attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg
    16141 aatcatgtag accaagaaag tcgtgaagcg atcatccagt tggtagacac acaaaaagag
    16201 ctctatgcgc ttcaaaataa tggaagagtt cctactgtgg aggaattgtt gaatgaaggc
    16261 tatatcaaac gagaacatgc agaaatctat cagcggcctt gaaggtaagg ttttagcatc
    16321 aggatatacg ttgtttgaat cactcttact gattttatta cttacaacga tcctttcttt
    16381 tccagttctc gcattttctg catggaagaa tgaattggca gtctatcaat ttttcggcca
    16441 atttgaaaaa cgaatctatt ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg
    16501 cttttattgg aatagtgaag agaatcaaat catttttcat gttccgaatc cagataaaat
    16561 aaattgggaa gtattagata ttcctgatga gattaccttg aaacgccatg cttctattac
    16621 ttttgctgct agaaccggga atgaaagttc actaaaagct tatcaatttt attgggaaga
    16681 aaaagagcgg acgattacgt atcaattcca gatagggagt ggtcgctata caaaaagaat
    16741 tgaataaaac aggatttgtt ttgttggagt cccttacagc gcttatgatc gcttctgtct
    16801 gtgtctactt agtgagcttt ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg
    16861 aggaactgct atttattcga atgatttatg aagatatcaa gacgcagcgg atgtatcaca
    16921 aaagaccaga gcgaagggaa gaaatgatcc catacgatat ccaaattgtc gataataatg
    16981 gagtaatcga aaaagtgttt gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa
    17041 gtaattccag catttacgct gattgaatgt ctaattggac tgatgatatt gagcagtcta
    17101 ttgctcacat tcaatctttt gattcagcaa accatccaag taagtgaatt tttgcagcgt
    17161 aaagatcaaa aagagtggct aatattttta gcacaattag aagaagaact caagagcagt
    17221 cacaatgtct ctgtgaaaaa tcagcaactg cactacacga tcgaggataa acagtatatc
    17281 atcgaaagat atcaggcaat gatacgtaaa agaagaactt ccggcggaca tcaacctatg
    17341 ttaacaagta tcactgagct tcaattattg gaaaaagaac acacaatttc tttttatgta
    17401 cactttgaaa atggagaaga tggatatgcc atatggacaa aaaacgatca gtagaaaatg
    17461 ttataagggc tctattttat tttctgtctt gcttttattt cttttatgta cgtttttatt
    17521 gatggcagca ttagaaagct accgtttgtc aatggatctt aatatacgaa tcaaaaatta
    17581 ttatatagca aaaataatga agcagatggc tttatcggaa cagtctacgc ttgccgaaag
    17641 ttcggaagga gttttttact acacaactgg atctgtaaca tatcagtggg tacaacagtc
    17701 cctattctta gaggtggaag tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa
    17761 tgatacagat actagtacag aatgatggaa tgttcgtgaa aacgccctct tttctgttat
    17821 aacactgttt ttaataaaaa aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat
    17881 tgaaattttg tcaattgttc gatagaatta aacaggtgaa aaaattgtta taatatatct
    17941 agaaatgagg tgcaccatgt taccagaaaa aatggaacaa gggtttaatc aaaacctgga
    18001 agctattcag cttttacaga atgcattggg aacttccttt ttagaagcct atgtcgaaaa
    18061 tgcagaaaat ttaatagatg attatcaagt acgtgtggtg gatggagtgc cgacaaaaga
    18121 gacaacgcaa cggatcacag ctctttatga agagttgaag aaactttctt tcgagccaga
    18181 agaatggcgc agactgtctc aattactttt attgaagggc agccagacag aacatttgca
    18241 ggcgaaccat caactcactc ctgatagtat cggtttttta tttgtttttc ttattgaaca
    18301 actatacaca aataaaaaag caccggttaa gattctggat attgcggcag gaatgggcaa
    18361 cttgttatta acagttcttt taaacctatc gaatgcgggg taccaaacag aaggaattgg
    18421 tgtggatatt gatgatacat tgttggctgt cgcagcttct acaagtgatt tgacacaagc
    18481 aaatgttcaa tactttcatc aagacgggtt gcaggaatta ttaatagatc ctgtcgattt
    18541 tgcaatcagc gatttgccaa tcggttatta tccgaatgac gaaaaagcaa aagagttttt
    18601 aacaagtacc gaagaaggcc atagttatgc acatcattta ttgctagagc aatcaatgaa
    18661 atatgtgaag ccggatggtt ttggtttgtt tttgatgccg agtggatttt tagaaacgga
    18721 tcaaagtgaa gaaatcaaaa aatggtttaa agaagaaggt tatcttcaag gaatgattca
    18781 attgccagat gaattgttcc gtaataaaca atcgcaaaaa agtattttga tcttacagaa
    18841 aaaaggacca caagcacaac aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa
    18901 agaaccagag aaggtgacgg aatttttcaa cgagtttaaa aactggaaat catctgctct
    18961 gtaatcattc aacgagaagg agagtcatat gtctaaaaca attgcaatca atgctgggag
    19021 ttcaagtttg aaatggcaat tatatcaaat gccagaagaa accgtagttg cgaaagggat
    19081 cgtcgaacgt atcggtttac aagattctat ttttaccatc aagtacggcg ataatcaaaa
    19141 attcgaacaa atcatggata tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca
    19201 gttgattgaa ctgcaaattt taagctctta tgatgaaatc accggagtag ggcaccgtgt
    19261 tgttcacgga ggagaaactt atggggattc agtagtgatc gatgagaaag taatggaccg
    19321 cattgctgaa ttagcagaat ttgctccttt gcataatcct gcaaacttaa tggggatcaa
    19381 agcgtttaaa aagattttac ctgacatttt gagtgtggct gtattcgata catctttcca
    19441 ctcaacaatg ccaaagcaaa attatttata tagcttaccg gtgtcttatt atgaagattt
    19501 caaagtaaga aaatatggct tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc
    19561 aaaattattg aacaaaccga tcgaagaact aaaaatcatc acttgccact taggaaatgg
    19621 tgtatcgatc acagcagtcg atggaggtaa atccatggat acttctatgg gattcacacc
    19681 attagctggg gtgacaatgg gtacacgttc aggtgatatc gatccagctg ttctcccata
    19741 tttaatggaa aaattagaga ttgatattga tgaaatgatc aatgttttga acaagaaatc
    19801 tggtctgcta ggcctaacag gattgtctag tgatatgcgt gatcttgaaa agaactatga
    19861 aaaagaacat attcgtttag cttatgacat tttcgtggac cgcatccgaa aatacatcgg
    19921 cggttatgtg acaacgatga atggtgttga tgcaattgtc tttactgctg gtatcggcga
    19981 gaatgacgga catgtacgta gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat
    20041 cgatccagcg ttgaatgaat tgcgtggtga agaagtagat atctctacaa aagaatcaaa
    20101 agtaagagta ttagtgatcc caacagatga ggaactaatg attgcccgtg atgtggagcg
    20161 tctgcgcggc taagccaaag cattcgttag gataaaagat gaaacgcatg caagagggaa
    20221 ttcttgcatg tgtttttttt gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc
    20281 cttctttttt acaggatctt cttagggaat tttgcttgga aaagtggtca aaagggaaaa
    20341 gactggcatt ttatttattg attttcagga aaatcccaat attttatttt cattcatctt
    20401 tataagggac attacatatg taaaaagaaa aaacattttt agatcagcct cgtgggctgt
    20461 cgactttatt cttcgcttta tgtttagcta gaaaaccgat ccgaaacatt cattgatcga
    20521 ataataaaaa cttgattttc cacctgtact ttgcctgaat cgtgaaagca caggtatgaa
    20581 aatcaagttt tttgttgcga aaaaacgtcc tagtcaatca gttggccgag cggctggcgg
    20641 ctgatctgct cctgatcaat aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg
    20701 tcatggctga ctgctaggag cgttccttga tagtcttgca gcatttcttc aatttcttct
    20761 cgagcatagc tgtcgaggtg attggttggt tcatccaaaa tcaggacgtt gattttttct
    20821 aaaaagagtt tcagcaacgc caaacggatt ttttcaccac cggataaatc tttgatccgt
    20881 ttacccacat cgctttgata aaagccactt ttggctaatt gccgtcgagc gacttcttcg
    20941 tttccagtca atgtgatggc gtaagccagc aaacggctat cgggatcggc aaactgcagc
    21001 tgctgcggca aataaccgat ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc
    21061 ttttcctcac cgagtaataa tttgagtaag gttgattttc ctgcaccatt gtcgccgatg
    21121 atggctaaat gatctccacg atagactgca aaactgctgt ctttgaatag tacttgatca
    21181 gcgtactgct ggtgcaagtt ttgaatgatg aaaacttctt tgccagattt tccaccatta
    21241 gacaagcttt gcagccgatt tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc
    21301 aggcggcgtt ccagttcttt ggcttttttg aagaaggact cattgtctcc ttcatgtgcc
    21361 cactgacgaa aacgacgaat catgactttc aaccgctgga cttctttttg ctgcagttcg
    21421 taattttttg tcagctcagc caagcgagct tctttcaaga ctcgaaaacg gctgtagttt
    21481 ccgggatact caatcaatgc accttcttcc agttcccatg tttttgtggt gacttgatcg
    21541 agaaattgcc gatcatgaga aacgaccaga accgattttt ttgtattctg taaatagttt
    21601 tccaaccagc gaatactgtt aagatctaaa tgattggtcg gttcatcgag taaaagtaaa
    21661 tcggcatcgg ctgctaaaat tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt
    21721 tctgttaacc gtgcttcctg acagtgtgga atccctaagc cttgcaagat cgctgcaatc
    21781 cggtcttcta atacgtaacc gcctagttct tcaaagcgat gctgcagctc accgtaacgg
    21841 gccagacact tctctaagtt tgtatctggt tctgtcatca atgcttcgta gcgactcatt
    21901 tgctgtttga ggtcctgtat ctcagcggca gaatggagca agtagtggtt gacggtcgct
    21961 tcggaaactg taagttcttg ttcgaccgtc ccgatcttta agcctttttt gcgactgata
    22021 acaccgctgt cgacaccttc tctgccggtc aagatttgta aaaaggttga tttgccagtt
    22081 ccgttgatat cgactaaggc aattttttca ccagcttcaa tttgacagga taaatcctca
    22141 aataatggat tcccgccgat tgttttttta atagaaattg cttgtatgat catgatctct
    22201 ctccttgaga ccactcaaaa aggccatggt tatccctggc ctgtgttatt taaactcaga
    22261 ttatcatgag aaaaatacct tgagatggcc attgatttta cgtgaattca actgttttgg
    22321 acaaacttgt cccgtcaaca gcaactgtaa aaccaattgc atggctaaat gcgatatggt
    22381 atcgttggta attttcatta cttgttattt tagtcatgcg catcatagta ttttccctcc
    22441 ttcgtgtagt tgtcttttcc agtgtacctg aaagtgtcag aaagttcaac tagcgctgac
    22501 atttacttaa tatttatcga tgtgtaattc tgtcagagag ctttttttat ctgactgagg
    22561 gtaatgtctc gtggaccaca tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca
    22621 tatggtgttt gataaaaaac tttgtctaca tgacttcctt ttgccatttg cttaataccg
    22681 ttgcattaaa cagctcttct ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt
    22741 gtggttgcaa tggcaagcgg tagcctttca tcaattcttg aatgatttac cgaatgtagc
    22801 acttgccttc tcgcggtacc cgaacccgaa ataaaatttt agtttggcga taaaatcggt
    22861 atccgccatc gatacttcat attttttcgt atcagattca tcggaaactt ccacattgac
    22921 gaaccaataa gctttggcat gcttaggtcg ttttaaacca caccagggcg actaatcgcc
    22981 ctggtgttca ctttttttat tttacttgaa ctcattgact gttttccctt tattttaaac
    23041 attataaaga ccgatgagtg cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa
    23101 aaaaacctgc cgatagttgg caggtcgtct acgtgttaag ctttggtgtg gtctttagct
    23161 ggcaattggt tttctaaatc agttcggaca acaagcacat cgcaagctgc gtttctaata
    23221 acatattcag aaacagaacc aataaataaa cgttctacag cattcaatcc tgtggctcct
    23281 aacataatca aatctacttg attatcttct gggatttctc tggcaataat ttgttttggt
    23341 gagccatatt ctacgacaga ggttacatta ttcaagccag ctttcttcgc attgctttca
    23401 taatctgcca atgtttgctt tgccatttca gtagcttgtt ctgcaagcat tccatcaaag
    23461 gatgaaacgg tttggaaaga acgtgtgtca atgacatgtg ctaatagaag ttctccgtta
    23521 tttcggatag ctacattgac cgccttttta aaagctaatt cagcttcatc agaaccatct
    23581 acggcaacca tgattttttt gtattgttgt aacataagca ttcactcctc aagtcaatcg
    23641 tattgtactc ttttattgta gaacacttta gggaaaaaga gaattattta ctgctttggt
    23701 tcagcaattt tttttgcaaa tcggatactg aaggtggcag aaacaataat tacgatcagt
    23761 aaaaagacca aggcaataaa gcgttgattg aaaaaagctg ttaaaatacc cattacgcct
    23821 aaaacagcat atgcagcacc gtaaaattgt aggaatcctt gatttttatc atttttgttg
    23881 atcaatacaa aaaagatatc ctgtttatta aataaataat agctaacgaa taataatact
    23941 aaagtggcga taatcattaa aatcctaatc atgaacaaat cctccaaaat aagcaacaaa
    24001 tagaaaaagc aatttgccaa gagcaaattg ctttattctt taaaagatgg taatctccgt
    24061 taatgccgtt gtttgtcctg tagtattgat cccgcgaatt caagcaggtg ggtcccatgg
    24121 tcgtagcttc gaactaccaa atgataaggc atgttaccag cagtgacaca agacgggtcc
    24181 caagatatca ataaaaatgt tcggtcaaca cacaaagagg acaattcgaa catcacagat
    24241 ttcccacctc tatagtagca tatgaattta aaaagagcaa tgagagagct cgcagaaaca
    24301 gaaccgtttt cttgtctagt tttttggagg atgctttttc cactctttta tacggtaata
    24361 ctgttgaccc agagcctgtt catatttccc tgtatctttt ggctgataat actgagcatt
    24421 cttcagttta tctggtaaat attgctgatt gacccaagcc tgatcaaaat gatgaggata
    24481 ctgataaccc acgccacggt tgagtgattt cgcacctttg taatggctat ctctcaaatg
    24541 atcaggaaca tctccagctt tgccctctcg aatatcagca agtgctgcat ctaatgccat
    24601 gtaggcagaa ttggattttg gcgacaagca aagatcgacg acgacgtctg ctagtgggat
    24661 acgtgcctca ggcaatccca atttttcagc agctaataca gcgttcactg tacgagccgc
    24721 agcagcagga ttacctaaac ctatatcttc ataaccgata accatcagac gccggcaaat
    24781 acttgccaga tcacctgcct caactaaacg ggcgagataa tgaagtgcag catccacatc
    24841 acttccacga atcgattttt gaaaagccga aataacgtca taatgagcat ctccattttt
    24901 gtcatgggta agagcttttc tttggacaca ttcttcaatg atcgacagtg taagatgaat
    24961 ccttccttct ttatctgaag gagtcgatag tgtagccagt tccagcccat tcaatgcact
    25021 ccgcaaatcg ccgttcgttg cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat
    25081 tgcttgttgt ccaaggccgc gttctttatc ccttaaagca tgttcgactg ccaactggat
    25141 gtcttgttct gttaatggtt tgacttcaaa gatctgtgta cggctgcgga tcgctggatt
    25201 gatggtaata taaggattct cagtagtcgc tccgatcaag atgattcggc cactttctaa
    25261 atgaggaagc agaaaatcct gttttgtttt atctaatcgg tgtacttcat ccaataagag
    25321 gatcactgta ccactcattt ttgcttcttc cgctacaact tgtagatcct tttttgaatc
    25381 tgtagcggcg tttagcatgc gaaatgcata attagtagag ccggcgatcg cacttgcgat
    25441 actcgttttt ccagtaccag gaggtccata tagaatcatg gaagagagca tgcgagcatc
    25501 gaccatgcgg cgtatgattt ttccttcccc gactagatgc tgctgaccaa cgacttcatc
    25561 gatcgttcga ggtctcatgc gataagccaa tggctgttgc ataggatttt cctccttctt
    25621 gtttttacgt cccttaatta tatcatattt agcaagatgc ctagaaagaa cagccttctg
    25681 ttgttttgtt ttcatagctt atccaactaa tattgtgtat gataaagtag gtgagaaaaa
    25741 tgacggataa acaaaagata gatgaatttt tttggaataa aacgacgcca gaagtggcac
    25801 gggatttatt ggggatgtat ttggagcatg acacaccaga aggaagatta gctggatata
    25861 ttgtagacgc ggaagcatac ctaggtccag aagacgaggc cgcccatagc tatggtttaa
    25921 gaagaacacc gcgtgtgcgg gcaatgtatg aaaaaccagg tacgatctac ctttacacga
    25981 tgcatactca tcggattttg aacatcatta ctcagccaga agggattcct caaggagtaa
    26041 tgatacgtgc aatcgaaccc gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa
    26101 aaactggtcc agatatcagc aacggtccgg gaaaattagt ggaagcatta gcaattcctc
    26161 aagaacttta tggtcagtct atagcagata gttcgttacg cttagttttt gagaaaaaaa
    26221 agacaccaaa aaagatcaat gctttgccta gaatcggtat cccaaacaaa ggtgtatgga
    26281 cagaaaagcc gttgcgtttt gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa
    26341 accaaatcga gaaagattgg ggttggagga aagaaaatga aaaagaagga tctattaaca
    26401 tatttagatg aaataattga aaaacaagtg acagactatg atgtagcttt agattgggat
    26461 acaaaaaatc atacgatcga gatcgttgtt cgcttgtttg cagaaaataa agcacaattt
    26521 gagattgatg atgcagaagg gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc
    26581 gtacttcttt ttaatcctca gaaatctgtt tttgatgaac gcaattatct agcagtaatc
    26641 ccttatgaag gaaaaaaagg gttggcaaaa tcagtagctg attctttagt ggaatatcta
    26701 aatgaagtat tagctcaagg gcaaagcgat ttgcttgatt ttttggatga agacgatgac
    26761 gaagctgtat tcgagcttca ctgggataat caacaactag cagaattagt agaagtaaaa
    26821 cagcaaaatg aagcagatac ttatttaccg tacccaagtt attaaggagt gacagatatg
    26881 aaatggaatg aagtaaaagt agaaactgaa agtgaagcag tcgaagcagt tgctaatatt
    26941 ttgatggagg caggggcgag tggtgtcgcg attgaagatt ctttagatgt tgaacatttt
    27001 cagtcggatc aatatggtga gattttagat aaaaatgatt ttacatcgct gaaagaaggc
    27061 gcactagtca tggcttattt tccggaaacg actttcttac cggaaatctt gccttttatc
    27121 aaagatcgta tcacacaatt acctgagttt ggtctagcta ttggaaaaaa taaagtaaca
    27181 gttagtgaag tagaggaaag caactgggca acagcctgga agaaatacta tcatccggtg
    27241 cgtattacgc gaatgctgac ggttgcgcca agctgggaaa actaccagac agaagatcct
    27301 ctagaaaaaa ttatcacact agatcctggt atggcatttg gcacaggcac tcatcccacg
    27361 acttccttga cattgacagc actagaaaca gtcttgcgtg gtggtgaaac attgctagat
    27421 gtgggaactg ggtcgggcgt gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc
    27481 tatgcctttg atttagacga agtagccgtt cgttcggcga aagaaaatat ggatatgaat
    27541 gaaatagcca aagatgtcca tgtatcagct aacgatcttt tgacaggaat cgagattgaa
    27601 agtgatgtaa tcgttgcgaa cattttagca gatatcatct tattgatgat cccagatgct
    27661 tggcgtttac tgaagcaaac aggcacgctg atcgtttcag gaatcattga agagaagaag
    27721 caaatggttc tggatgccat gttagaacaa gggtttatcg tggatcaaat tttccagcaa
    27781 aaagactggt atgcaattat tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt
    27841 ttaaaagaat catatgaatc aaaagactat tttgttttag aaggggaaaa ctatcaccac
    27901 attgtacggg ttatgaggat ggaacccgag gatgaagttt ttttggcatt caatgatcaa
    27961 atagccattg ttgcagaaat cacggagatt actgaagagg ctgtttatct gaaagaaatt
    28021 aaaaaagaag aaaatcaaaa ggaactgcca agttcgatta ccatagcgag tggctatcct
    28081 aaaggggaaa agctggattg gatcgttcag aaatccactg aattaggagc gcaagctttt
    28141 cttggtttcc cggcatcagc ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga
    28201 caacaacggc ttgaaaagat tgctcaagag gcagcggaac aatcccatcg gcagatcgtg
    28261 ccatcagtag agttattgga aacgaaacaa gatttatttg agcggctaga tgattatgac
    28321 gtggtcttgg ttgcttatga ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa
    28381 attcttagtg aaacaaaacc agatagtcga atcttagctg tctttggacc agaaggtgga
    28441 ttatcccgcg atgaagtcga ttattttgta gaacacaaag ggatactttg tggattagga
    28501 ccaagaatcc ttcgtacaga aacagcacct ctttatttat taagtgctgc tagctatcaa
    28561 tgggaattaa tgaatccttc tttcagctaa cgttcttcat taataaaaga gtatcgacag
    28621 aaagaattga aaaaatagtc aacaatttgt ataatagaaa caattattta tacaatggat
    28681 acgaaaaatc gtttgaaaaa gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac
    28741 tgcacggatt ttgggacaat tatcaaacag atatttgtcc cgattcccgt tttaccgaaa
    28801 aaagaaaggg ggatcgattc ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat
    28861 aaagctcgtt agtcaataca tgggtcccga acatgtagca tttgttgaga aagcatgcga
    28921 atacgcgact gctgcacatg acggacagtt tagaaaatca ggcgaaccct acattattca
    28981 tcctatccaa gtcgcaggta tattagcaga tttaaaaatg gatccccata cagtggctac
    29041 aggcttctta catgatgttg ttgaagatac agaaatcact ttagaagatc tgagagaaga
    29101 atttggcgat gacgttgcta tgttagtgga cggcgtaacc aaattaggga aaataaaata
    29161 taaatcccac gaagagcagc tagcagaaaa ccaccgaaag atgctgctag caatggctca
    29221 agatttacga gttatcatgg tcaaattagc tgatagacta cataacatgc gtacgttgaa
    29281 gcacctgcga gaagataagc aaagaaggat cgctcaggaa actttagaaa tctatgcgcc
    29341 tcttgcacat cgtctaggga tcagccggat caaatgggaa ttagaagata cagcacttcg
    29401 ttatctaaat ccaaaacagt attaccgtat cgtccacttg atgcagacga agagagaaga
    29461 acgtgaaaaa tacgtaagtg gtactgttga agatattcga atagcgacag aagagctggg
    29521 gatttttgca gaaatctatg gacggccaaa acacatttat tcaatctatc gtaaaatgaa
    29581 agatcagaaa aagcagttca acgaaattta tgacttgcta gctattcgag tgatcgtaga
    29641 ttcaatcaag gattgttatg ctgtattagg agcaatccac acaaaatgga aaccaatgcc
    29701 cggcagattt aaggattata ttgccatgcc aaaagctaat atgtaccaat ctttgcatac
    29761 taccgtgatc ggtccggcag gaaatccggt agaaattcaa atccgaacac aggaaatgca
    29821 tgaaatcgct gaattcgggg ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa
    29881 agtagaacca gatggtatga cgaaacaatt aagctggttc catgagatac tcgaacttca
    29941 agacgaaagc tatgatgctt ctgaatttat ggaaggcgta aaaggagata tctttagtga
    30001 taaagtctac gtcttcacac caaaaggaga cgttactgag ttaccaaaag gatccggacc
    30061 attggacttt gcatacagta tccatacaga tatcggtaac aaaaccactg gtgcaaaagt
    30121 aaatggcaaa atggtgcagc ttgattacaa attgaaaaac ggagatatca ttgagatcat
    30181 gacttctcca aattcatttg gcccaagtcg cgactggttg aaattagttg ctactagcaa
    30241 agcaagaaat aagatcaaac gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa
    30301 aggccacgaa tccgtggtca aatgtattac agatctagga tttacgccta aagatatttt
    30361 gacgaagaac aaactgcaag aagcactcga tcgttttaat tatcaaacag aagatgatct
    30421 ctatgcagct gtagggtatg gagaagttag ccccttgacg atggccaatc gtctgactga
    30481 aaaagaacgt aaagaacaaa aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa
    30541 tcagccgaaa aaagaacctg acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca
    30601 aggggtagaa aacttactaa ttcgtatcag tcgctgctgt aatccgattc ctggtgatga
    30661 tatcgttggt tatatcacta aaggcagagg gatatccatt catcgtcgag attgtccgaa
    30721 tgttcagcct gacaaaccaa atgtagcaga acgtttgatt gaagtcgaat gggaagatac
    30781 atcgaataca cgaaaagagt atgatgcaga tttggaaatt tacggctata atcgttcagg
    30841 cttattgaat gatgtacttc aaacagtcaa tgcgctaacg aaaaatctca acagcgttga
    30901 agcacggacg aataaagata aaatggcgac gatccatttg acggttggta tccagaattt
    30961 atcccaccta aagagtatcg tggataaaat caaagcagta cctgatgtct acagtgtacg
    31021 ccggacgaat ggataggagg acagatatga gagcagttgt tcaacgggta agtaaagctg
    31081 ctgtgtcagt cgatcagcaa gaaattggaa aaattggcta cggcctactt gttttattag
    31141 gcattcatga aaccgatacg caaaaagatg tggactatct ggtaaaaaaa attgcacaaa
    31201 tgcgtatttt tgaagatgaa caaggaaaaa tgaatattag tgtagaagat gtgggaggac
    31261 aaattttaag tatctctcaa ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa
    31321 gctttgtgga agccgcacga ccagaaacag ctattccttt atacgaatca ttcaatgaag
    31381 gaatcagaag tcgcggcatc acagtcgcta ccggacaatt cggagcagat atgtcggttt
    31441 ctctcgtcaa tgatggacct gtaacgatca ttattgattc taaaaacaaa taaagtaatc
    31501 tggttttcac tagtaaaaac tatgaaacac gtcgcttaag ttagactgat aaactctaac
    31561 ttaagtggct tttttgtctg caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta
    31621 agcttaaatt atacaagtta ttttttatag gaggttgctg aagatgaaag aagtaccagt
    31681 agtagatatc aaaatcacag atttaaaaaa attgtatcaa aaaggataca acatgttgga
    31741 ggagttacgc catgaagcgg acgctcccgt cgtcaaagca aagattttca ataaagaagc
    31801 tatcacgatc tacggatcat cagcagcaaa agtattttat gatccaagga atttcaaacg
    31861 aaaaggtgct atgccaaaat tagtattgaa gacacttttt ggtcaaggtg gagtacagac
    31921 tttggatgga gctgctcatc accatcggaa aaatattttt atggatctaa tgacaccgga
    31981 aagaatggaa gattatcatc gtatcttaga taagaatctg acacaagcac ttgaagcaca
    32041 gcatggtcaa tttgaactat ttgatttaag taagatggtt ttctttacat ctatttgcga
    32101 gtgggcaggt atcaatttat cagcgatttc taaagatgag gtcgaaaaat tagcagaata
    32161 tcaaatctct atgatcagcg gaacgtttac ttctccgatt gatcacataa aaggtgtcga
    32221 gaatcgcaaa aaatcagaaa aatgggcgca aggcttgatt gaagaagctc gacaaaatcc
    32281 tgtggctgga aaagaaaatg tggcattata tgcttttgcc aatgccacag atttagatgg
    32341 tcagctttta cctctggaag tggcagctgt tgaattattg aacatcatcc gtccaacggt
    32401 tgctctaact gtgtgggcgg cattgatggg acatgcactt ttcagtagac cagatttgta
    32461 tcagcaatta aaaaatgact tttcgacgtt acaagatccg tttattcaag aaatgagacg
    32521 ctattatcct ttcttcccaa tgctacctgc gatttcgctg aaagaagtag aagtagatgg
    32581 ttatcgtata ccagaaggca gttgggttat tttagattta tatggaacag accatgatga
    32641 acgaacagtt gaagcgccag attcctttat gatcaaacgg tatgtaggga aagcaaaaga
    32701 tatttcctat aaagaagaat atgagatgat tgcacaaggc gggggaaatt ttcgacaaat
    32761 gcatcgctgt gcaggagaat ggatcactct tcatagtcta cgtgtgtttt ccgatcagct
    32821 agtaaataag tttgagttct ctgtacctga acaagattgg acgattccat tcaatcagtt
    32881 tccgacttat ccgaatagcc gagcgctact ttacaagaat tagattagca taaacttatc
    32941 gaaaaaaagg aagatcaaac agtgctgatc ttcctttttt catattacta taaattgata
    33001 aggtcaattg atcaaaatcc acgaaatgct tcatcaatgg tttgataatc ttcattggat
    33061 aaatgcaaat ctaaagcttg gacattgtca gatacttgct ctggacgctt agctccaggt
    33121 ataactacag acactcgtgg attcttcatg taccaagcta aaacaagttg cgcaggagtg
    33181 gcttggtatc ttttagcaat ggggcgaagt acatcgacag cggttaaaat ttctctgaaa
    33241 cgttctcctt ggaaatctgg atttcttttt cgaggatctc cttcaccaaa ttgtttttcc
    33301 tcaccaagtt catattttcc tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa
    33361 ctgattttgt ttttttcaag ataagggaat aattcttttt cagcctgccg atggatcaaa
    33421 ctgtatttat cttctactac atcgacatat ccatctgcat tcgcttcttt caattgttct
    33481 aacgtgaagt ttgacacacc gactgctcgg atttttcctg cttcttttaa ttcgtgcaat
    33541 gtagcaactg attcattttt tggtgtgctt tcatccggaa agtggatata aaaaatgtcg
    33601 atgtaatcag tttgcagacg ttttagtgca tcttccaccg attgtttgag aaactcagga
    33661 gaattatcaa atgttcgccc tttatttggt acatgagcag cttttgtagc gatgacgaca
    33721 cgtgagcgat catattcttt ttccttcagt acctcgccaa tcagttcttc ggaacggccg
    33781 tttccgtaag cataagcggt atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact
    33841 acttgttttc ctgtctcatc ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt
    33901 gctcctaatc caagctgttc tgcgtagact tgtgaatgtc cgattcttat ttctgccata
    33961 gctgattcct cctttttgtc tagtctaaaa caaaatacca aaaagctgaa ctaaaacgtt
    34021 tttgtgaggg gaaatagtca gatatctctt gactttgaga ctggttttta gtaggttata
    34081 agtaatatcg aatgtcaatg aaagagcgag taagtttttg aaactttaca agagaggatc
    34141 atcgaggctg aaaatgatct aaagtttcat tagcctaaag acactctgga gatggacgag
    34201 tgaaaagccg tcccgcgtac gagcgttatt cgtaagagga aagagaaatc tttcaaaatt
    34261 aggtggtacc gtgtatgaat ttcattcacc cttgttcatg atgaacaagg gtgatttttt
    34321 tatttacata gctaagaaag ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa
    34381 atgatatttt gccaggcgaa tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat
    34441 tattcagaga ttatcagtat aatgaaatgc gtacaccgat ttttgaacac tatgaagtga
    34501 tatcccgaag tgtaggggat acaacggata tcgtttcaaa agagatgtat gatttttatg
    34561 acaaagggga acgccatgtg acgcttcgac cagaaggtac agcaccaatc gttcgttctt
    34621 ttgttgagca taaattgttc ggcccagagt atgcgaaacc gttcaaaact ttttatatgg
    34681 gaccaatgtt tcgctacgaa cgccctcaaa aaggacggtt acgtcaattc catcaaatcg
    34741 gagtagaagc atttggatca gaaaaccctg caactgatgt ggagagcatg gtgatggcac
    34801 ttgatttctt caaacagttg gggatcacgc aaatccggct agtcatcaat tcattaggtg
    34861 ataaagaaac gcgtcaagcc tatcgtcaag cattgatcga ctatctttta ccttttgaat
    34921 cagagctgag tgaagactct aaacgccgcc ttcatgaaaa tccattacgc gtattggaca
    34981 gtaaagacaa acgagatcaa aaatttgtgg cagaagctcc atctatctta gattatctaa
    35041 gcgagcctgc tcaaaaacat tttgataccg ttgtttccat gctggatgca ttggctgttc
    35101 cttatgaaat cgacagtaat atggttcgcg gactagatta ttacacacat acgatttttg
    35161 aaatcatgag tgacgcacca aaaatggggg cacaagcaac gatttgcgca ggcggacgtt
    35221 atgacaatct agtggaagaa ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg
    35281 gtatcgagcg attactcttg actatggagg cagaggaagt agttatccct gcatttaatg
    35341 agttggatgc ttacgtggtc gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg
    35401 tccaagcgat tcgaaacttt ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa
    35461 aagcgcaatt taagacagca gataaagcga atgccaaatt agtattggtg atcggtgaag
    35521 atgagcttgc tagtcaaacg attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt
    35581 ttccattaga agagatatat gaacattttg atgaagtcta tgatgaaatg actttattcg
    35641 agtaggagga aaaaaataaa tggcacaaag aacgatctat tgcggattag tttccgaaca
    35701 acaattagaa caaacagtta cattaaaagg atgggtacaa aaaagacgag accttggggg
    35761 agtaatcttt atcgacctac gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga
    35821 aatcaacaaa gaagcatggg aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt
    35881 gactggggaa gttagaagac gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga
    35941 attcgaagtg attgcaagtg aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca
    36001 aattgaagat gatcaagcaa tcagtgacga aatacgtttg aaatatcgtt atttggatct
    36061 gcgtcgtcca aaaatgacta aaaacatcaa attaagaaat gcgacaacaa aagcgattcg
    36121 tcattattta gatgataatg actttctcga tatcgaaaca ccttacctag ggaaatctac
    36181 accagaaggc gcaagagact acctagttcc ttcacgtgtc catgctggac atttctatgc
    36241 gttgccgcaa tctcctcaat tgtttaaaca attgctgatg aatgctggat tcgaccgtta
    36301 ttatcaaatc gttcgttgtt tccgcgatga agatttacgt ggagaccgtc agcctgaatt
    36361 tacgcaagta gatattgaaa caacgttctt aacagcagaa gaaatccaaa cttacacaga
    36421 gggattgatt gcgaaggtaa tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc
    36481 tcgtatgacc tatgatgaag caatggctcg ctacggcagc gacaaaccgg atacacgttt
    36541 tgatatggaa ttgatcgatc taagcgatac agtcaaagaa gtagaattca aagtcttcca
    36601 aatggctctt gaaaacggcg gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg
    36661 ctactcacga aaagacatgg atcagttagg tcaatatgta ggacaattcg gagctaaggg
    36721 gcttgcatgg ctgaaagtag aagaagacgg attgaaaggt ccaattgcta aattcatggg
    36781 agaagcaaca gaagcaatca ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt
    36841 tggcgcagat aaaagtgaaa tcgtcgctgc tgcattaggt gctatccgga cacgtttagg
    36901 aaaagaatta ggactaattg atgaatcgaa attcaatttc ttatgggtaa ctgattggcc
    36961 acaatttgaa ttttcagaag aagaaggtcg atatgtctct gctcaccatc cattcacgat
    37021 gccaaaagaa gaagatatcc cgttattggc tgaagaccct gcaaaagtct atgcagaagc
    37081 ttatgatatc gtcttgaacg gttatgaatt aggcggaggt tctatccgta ttcatactcg
    37141 tgagcttcaa gaaaaagtac tagaaactct aggctttaca aaagaacaaa tggaagaaca
    37201 atttggtttc ttgttaacag ctttagatta cggattccct ccacatggcg gtattgcatt
    37261 aggattggac cgttttgcaa tgttattagc cggagaagat aatattcgtg aagtcattgc
    37321 ctttcctaaa aacggaaaag cagcagatgt gatgagtgat gcaccaagta tggtttcgcc
    37381 tttacaattg ttcgaattga atattgatgt aacgaatata gaagaatagc cgataaaaag
    37441 gtaaaaagga tttgtcgaat acgcttcttt tgacaacctt gatttaattg aaaaacactt
    37501 tataatgaag ccataacata taaagcgggg cttttccatg aaaaaaacat tcgaaaattg
    37561 ggcttatcat gattacacga ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc
    37621 agtcgcattg aatttctttt atcagccagg acatatttat tcaagtggta ttactggtct
    37681 agctcagatt ttgacgactt tgtcaaaatc actgatagga ttcgaagtac cggtatcaac
    37741 aactttgtat ttactgaata tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa
    37801 gtttacaatt ttcactttta tcacagtcac tttgacctcc ctttgtatcc atattttacc
    37861 ggaaacagtc ctatctaccg atccaatcat ctgtgcgttg tttggggggg ctgtgatggg
    37921 actaggtatt gggctagcgt tgagaaacgg cctatcatcg ggcggtctag atatcgtgag
    37981 tatcacgatt cgtaaaaaaa caggaaagtc gattggttct atttcgatct acttcaatgc
    38041 attgatcgtt tttgttgccg gaattctatt tggctggcaa tatatgtttt acagtacgtt
    38101 gtctattttc gtcagtggaa aagtaactga tgtcgtttat actaaacaaa agaagatgca
    38161 ggtaatgatc gtaacgaaac atccagaaaa agtagtaaat gaaatccaaa actgtatgcg
    38221 tagagggatc acgatcatca atgaagcaga aggtgcttat aagcatgata agcagacagt
    38281 attgatgacg atcgttacac gatacgaact gcctctactt agagaagcaa tgaaagcttc
    38341 tgatccacaa gcttttgtaa gtattgcaga aaacgtccag atacttggtc gtttctatga
    38401 ggatggcatt tagatcgagt ttgacaaaaa ttcatgaaat actgctgtag acagacgttc
    38461 gtttgtctgc agtttttttc taccatagta gaatcagcaa agaaaaactg cttttttatt
    38521 tgaaattttc ttaaagttga aaaaaagcat gtttattttt ttaaatttat gggatgatag
    38581 aaaaaaatag tagagaaagg acacgattct acttgctatt ttcacttaat acccgtatat
    38641 tacgaatgaa aaaagtttat gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa
    38701 aaaacagccg ctacatcact gggtttgatg ggctccgttc attagctgtg gtgggtgtta
    38761 tcttctatca ccttctgcca actagtatga aaggcggcta tttgggcgtt ccgatttttt
    38821 tcgtcgtatc tggttatttg atcacggatc tgctgcggca ggaatgggaa caaaatggaa
    38881 aaatcaatat ttggcaattt tatgtcagaa gaatgaagag actctatccg gcacttgttt
    38941 ttatgcttgt gacagcttcg gcttatatca ctttgtttca gcgagggctg ttaaacaatc
    39001 ttcgaggagt tgtggtcagc agcttactgt atgtcaacaa ctggtggcaa atcaataacg
    39061 gtttatctta tttcgatcga tttgctaatg agtcaccgtt tacgcatatc tggtctttag
    39121 cagtagaagg tcaaaactat ttggtttggc cgatcttgtt tgtattgttg atggtatttg
    39181 ttcgtaaaag aaaatggatc ttttatactg tgttaggtac atccttcctc tccgccatct
    39241 tgatgatgat cttgtataca ccaggaggcg atccaacccg tgtttattac ggtaccgaca
    39301 ctcgtctgtt ttctatatgg ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt
    39361 taaagaaaaa catcccgaaa caagcgaaaa atattctgaa tatcgctgga ggaatctcgc
    39421 ttttggcact gattctttgc ttcttctttt tagatgatca ttacaatttc atctattacg
    39481 gaggaatgct cctagtgagt ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg
    39541 gagcaagttt gaatcgatgg ctgacaaatc cagtatttac ttggattggc aaacgaagct
    39601 atggcattta tctgtatcag tttccagtta tgatttttta tgaagcaaag gtgactgata
    39661 ttgccgatca tgttttgttg catactttag tggaaatcac attgattcta atcatcagtg
    39721 aactttctta tcgatatgtg gagcgtccgc tagcacgttt tgattatggt cgtacattcc
    39781 aagtgatgaa aggatggttc agcaaaccga tcatcagtaa gagcaaacca tgggttgttc
    39841 caggcacatt acttgtagca attgcactcg ttggtttcgt tacggcaccg aaaaacgctg
    39901 taacagccga tcaaaaacaa ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag
    39961 aaaccagaaa caattcagaa aacaccacta gttcggttga ccaagcgatc cttgataagt
    40021 acgagttgtc caaggcacaa gggaataagg cacaaaaatt agaactaacg gcatttggtg
    40081 attcagttat gttggatgct gcaacggatc tacaagaact ttatccaaaa gtagtggtag
    40141 atggagatgt cggacgacaa ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac
    40201 aagatttgtt gaaagacact gttctgattg gactaggaac gaatggctca ttctcggaag
    40261 ctcagtttga tagtgtgatg gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc
    40321 gagtaccgac gaagcgctgg caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa
    40381 aatacgacaa tatgacgctg attgattggt acagctacag taatgaccat agtgactggt
    40441 tttatgatga tcaagtccat ccaaatcctg aagggatgac acattacatt cacttagtca
    40501 gcgaagcctt gctaggagga agttcaagta cgaacagcag tgagacaaac gtgacagaat
    40561 gatagctaca aaaaacttca ggcaaaaaca tttgtttttg cctgaagttt ttttatattt
    40621 accgtgtttt taacattcat atagattcag gaagcaaaac ggttgagtgt gtctgtaaat
    40681 aacgttcttt ttgttttcgg gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc
    40741 ttcttgaaga aaatacttct gcatggatca tcttaacagg tcttcttttt tgaagacgag
    40801 tatatttagc accagtacca ttgttatgtt cctctaatcg tctagaaaga tcggttgtat
    40861 atccaccata aaatgtctga tctttacaga ataatacgta aaaataatgt tcatttgcca
    40921 tagagcatct cacgaatctc tgcagtgtat tctccatcca tattgtaagt gatcaatggt
    40981 ggagcgactt tgaatccgtc taatttgcct tctttgattc cttcaactaa caaaatattt
    41041 gcctcttttc caggttttgg gtaaacaaat tggatccttt taggtgcaat tcgatagtct
    41101 tccatgacct gaatgatttc taagaaccga tcaggacgat ggaccatagt aaagcgtcca
    41161 tttgttttta gtagcttact tgaaatatcg atcacttctt ctaacgtcgt atgaatctca
    41221 tgacgggcga ttgccaggtg tttattaggg ttcgttttat ttgttggcag ccctttgaaa
    41281 taaggtggat tacagacgac taagtcacaa gaattatgtc gaacgacaga taagctgtct
    41341 ttcagatcga tggtgtggac agtcatttgt tcatttaaat ggttaagcgc gatactacgt
    41401 cttgccatgt ctgctagacg aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt
    41461 ttacttaaaa aaagtccaac tgcgccattt cctgcacaaa ggtcaacaat cttccctttt
    41521 ttaggtacac gggaaaagtg agcaagcagc acagcatcta aagaaaaaga aaacactttg
    41581 gaactttgga taatcttgat atcttctgcg tataattggt cgattcgttc gtcttcgtga
    41641 agcatggatt ccctccaaaa tgaaaaaaat agtcgtctgt attatactat ttttattaaa
    41701 aagaaccaag gtggcttgtc aaacctctat tttttatgca tactatgacc ataagaaggg
    41761 aaaggaagag actatgtttt atcgatttat gcgcggggta gttcgagtac tattagcctt
    41821 agttaatgga aatgcccgct atgagaataa agaagtttta ccgcaagatg agaattacat
    41881 actagttgct ccccatcgta cttggtggga cccattatat ctggcggtag ctgcagcacc
    41941 caaggaattc agctttatgg caaaagaaga actgttcaaa aatccagttc tgcgatttat
    42001 attaactcga tccaatgctt ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa
    42061 aacacctgta aagattttga aatcgacaaa tttgagtttg atcatgtttc ccagtgggac
    42121 aagacatgct acagaactta aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa
    42181 aatcgtgcca gctgtatatc aaggtccgtt gacacttggg gatctgttca agcgtcagag
    42241 agtgacagtg cgtttcggcg aaccaatcga cttatcagat atcaagaaaa cggataaaga
    42301 aggtatggcg gagatcgaac gacgaacaca agcagctttt gacaaattgg acaaagaagt
    42361 gaaccctgat ttcaaatatg aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg
    42421 gtcttttgaa tctactgtcc tgttcagttc agactttttc aatgaaaacg agggagagac
    42481 gtcaagtctg ccctcttttt gcgttccaat atgtaaaata gaagacaggt gtcatgtaat
    42541 ggatcaaagt gttataataa ttagaaggac attttttgag gtgattgaat gcgtttttta
    42601 catacagccg attggcatat cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag
    42661 cgtcatgtac tatcttctat actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg
    42721 attgccggag acttatatga taggagtgtc ccagctgttg atgccgtaga attatacaat
    42781 gaattgatgg tcgattggaa tttaaaggaa aagatcccga tttttgctat atcaggaaat
    42841 cacgatagca gtacgagact ttcagcgggt acgccatggt tcagttattc gaactatttt
    42901 ttgcgaacac agctagcaga agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc
    42961 tttcttcctt actttgaacc aattgcagcg agattatatt ttgaagatga caatatccga
    43021 acgatcaagc aagcggtagc caaggtgata gataaaatgc aggagctatt tgattcagaa
    43081 aaaaaacaag tattgattag ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa
    43141 acgaaaatcg aagtaggcgg gttggattcg atccctggtg aactacttac accgtttgat
    43201 tatgtagcac taggacattt gcataatcaa gctgctttga gacaggataa tgctcgctat
    43261 agcggttccc cattgaaatt ctctttatct gagatcaacc aaaaaaaagg cgtatggatc
    43321 gttgacctga caacaggcct ggagttgaat tttagggaga tcgaacccct gcatgatatt
    43381 gaagaaataa cagcgagttt caaagaattg ctggatcctg ccttttatca gtccgtcaat
    43441 cgggagaatt acatctatat ctatctcact gatagaacga tcatcccgaa tatgatgaac
    43501 cagcttcggc aaatatatcc tcgtattttg gggattgaac gggcaaacgg tcgagcagaa
    43561 caaacaaagc gcaaacgaaa agtactagaa atgaaagatc ctcaaaaatt agcagaagca
    43621 ttttttagtg aaatgacgga agagcagcta actgcaaacc aagaaaaatg gctcggagaa
    43681 acgttgcaag aaatcatgga aatggaatga tcaagaatga aaccgaaaaa attacaactt
    43741 aaaaattttg gtccttttat caatgagacc gtagattttt cacgtttgac agaagcaccg
    43801 ctttttttga tcagcgggaa gacaggagct ggcaaaacga cgatttttga tgggatcacc
    43861 ttcgcacttt ttggtgaaac ttccggaaga cttcgctctg gaaaagagat gcgttctttg
    43921 tttgctacac cagacgaaga aacaagcgtg actttttctt ttgaacatca gcagatgagc
    43981 tatgaaatcg aacgaaaacc agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa
    44041 aaacaggcag ccaaagtaac gttgaccatt tttgatggga aaggaaaaga aataaaacaa
    44101 atcacaaaac gtacagaagc agatcagttg atcagagaac tgatgaatct cgatgcgaaa
    44161 cagttttctc aaatcgtttt actaccccaa ggagaattcc gtaatttttt ggtttcatca
    44221 agcagtgata aagagactgt tttacgtcat ttattcggta ctcaattttt ccaacagttc
    44281 aatgagcgat taaaagaaaa agcaaaacaa cagcaacaaa aattggatca tttagagcaa
    44341 gagctgcatc ttctgcaaaa aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg
    44401 tttgaagccg ttttagccca atggacaaac catcaggcaa tactcgaaaa acaaatcacg
    44461 gaagaaaaag aagctctaac ggaacttcag gaaaaacaaa agcaactaga aaattcctac
    44521 tatcgttttg aaagcttgaa aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa
    44581 aaggaattag ctgctcaaaa agacgaaata gaggaaaaga aacgatggat tgggtattat
    44641 gaatttacgc aacgattagt cgaaccaatc cagcgcctac aagaaataaa agttgaaaaa
    44701 atagaactgt cacaaaaaag tagtgagcaa acaaagaaac tagcgatgac tacgcagaat
    44761 tatgaagagt ggcaaaaaaa tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa
    44821 gctgctcaaa aactgcaaaa caaacagatg atggtgccaa ttgtcgaatc cttacgtagt
    44881 aaaaaacaag acgcagaaca attaacaatt tcattggata aagaagaatt gaatgccgag
    44941 aagctgtatc aaaatctcgc tatctatcag gaaagaactc gaattcttca agaaaattta
    45001 ctggatcagg aaaaactgca agaagatcgt cttgcttttg gacagttaaa atatctagat
    45061 gaaaagcagc aagaaataga aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata
    45121 agagaagaac tcaaaaaagc aactgaagaa ataacaaaaa atagtcagct attgaaagaa
    45181 cagacagaac aagcagaaca gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt
    45241 cagctttttt tgcgtccagg ggagccatgt cttgtttgtg gatcaacgga acaccccata
    45301 caacaattaa aacacgaaca gccaaataag gaagatatct taaaagtaga acaacaactg
    45361 gcagaagctg agtctgctgt agaaagaact cagcaaatca ttgccaaaag tgaagcacat
    45421 gaaaataatc ttcaacaaca attatcagat ttagaacaaa aaatcatggc aacgaatata
    45481 caattggctg aacaagaaga acacttgcaa caggctttga aaaaggcatt tcctgagata
    45541 acagaacaaa aaacaaaaac aactcttgta gtaatcgaac aatctttaga tagacgaaaa
    45601 agcaagatgg ccaatgaaag aatagagctg gaagaaataa gacaacaagc agaaaagctc
    45661 gaacaacaat tagctgtcta caaacagcag cagacagaaa aaaataatca gctccagcaa
    45721 ctgcaaggag aaatcaaaag tttagaacaa caattgcaag atacggatag taactgttta
    45781 gaagaggaga tacgacgact tgaaaaacag ttagaagaag actcgaatca actagctgtt
    45841 gagcagaaag caggagtgca attgttgcaa gatcttcata cgcttcggac acagcttgat
    45901 cttcaacatg aacaaataga aaaaatagat gaaaaaatag aaaaggaaca agaaagaata
    45961 gctaaaaagt tagaaagcca gtcgtatttt tcaacaattg aagaaatctg tgcatttgca
    46021 caacagcaag cacaatataa agaaaaccaa cgtacagtta cttcttatca tgaagagcaa
    46081 ttagtgacag ctgaccggct gcgtcaatta gaaaatatcc agctaactga gacattccca
    46141 gatacagaag agatcagcca acagttagaa gaaataagac gtatgatcga aataaagcaa
    46201 gaaaagatat acggtttaca agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt
    46261 ctttcgattt atcacacaag ccagacgaaa ttagatgagc ttacgcaatt acagcagctt
    46321 tcgcaaacat tcaacggaga aaatcctaag aagactagtt tggaacggta tgtgcttcag
    46381 gtttatcttc aagaagtgtt acaagtagca aatgatcatc tccaacgttt aacgaaaaat
    46441 cgttatcaat ttgagctagc ggataccatt ggcagttatc gagggaaaac cggattagaa
    46501 atcaatatct atgatgatca ggcaggtatg tctcgaagtg cgcataccct gtctggcggt
    46561 gagagtttta ttgcagcact ttctttagca ttagctcttg ccgatgtgat ccagacacaa
    46621 gctggtggtg tagcaatcga tgcattgttt attgatgaag gatttgggtc attagatgaa
    46681 gaagctttgg aaatggcaat ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc
    46741 ggcatcatta gtcatgtaag agaattgaaa gaacgagtat tacaacaaat aagaattgat
    46801 acagaaggta gcggacaaag caaaatacgc tatcaacttg gataaaaagg gagattggta
    46861 actatgaaat ggagtattcc agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa
    46921 ggccgagtgt tatcggttgt ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg
    46981 ggcagtgaat tgtatatggt tgatttggat ggtacagcaa aagagataga ttactgccaa
    47041 tgtccctatt gggaggaaca taaatattgt aagcatacag ttgctgtgga actttattta
    47101 cggtcgaaaa atctatctcg tatcatgaaa aaagaccagc caatgctaga accggtaaaa
    47161 gcaacaagtg agggagaaat cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat
    47221 cctcaagcgg tgcaaccttt gattattgaa taccaagtag aaacgattga gactaatcag
    47281 tatcacccag agctttctat tttggcactt tacttgcgta tcggttcatt ggcatcaccg
    47341 aaaaaaacat atatcgtaaa aaacatctat gattttttac aagcttacac agaaaaagaa
    47401 acttacactg ttaataaaca gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa
    47461 gatcaaaaaa tactcacgca tcttgcagga agtgctcaga cgcatcaatt attaggtacg
    47521 aacggcttac aagtcaaagg aaaactagat aaaagatatc tgcttctccc agtagaacaa
    47581 gcccgcttcc tgttagagca gatgaatcag actacacgtt tgcatctgca gataaatgaa
    47641 caaaacgatc aaggaataca attttctgat caaaacaaac ctttatcatt caaagtggaa
    47701 aaatttggag aagattattt gctgcaagca ttgaatgatt ttgatttttt ctttatgcat
    47761 tatcagtggg gagttatcca agggacattt tattctctga cgaaatatca acaaacggtt
    47821 tatcaaactt ggaaacaatt gattcgccga ttggagaaac cagaagtagt gttcaagaaa
    47881 aaagaattac cgtctttgtt taaagagatt atccctctgc tgtcagagat cggcgacgta
    47941 gctattgccc ctgcagtaga agaggaagta gcagatatcc ccgtcgaatt tattttcttt
    48001 ttccgaaaag caaaaggaaa aatccaagct cgagtcgatt tcgtctatgg tgaagtcatc
    48061 tattcgactg acccgaagca tgaggtctcg acagaacagg cttttcaggt gttacgtgac
    48121 acagtagaag agaaacgagt acttgatcta ttcagaatgt atcgctacca gaaaaatgaa
    48181 actggttatg aacgtccatt gccaagcggg gaagaactat atgccttttt ccgcacagaa
    48241 ctatctgtct tccgtcagtt tggtgaagtc agacttggaa gaaaattgcg agagttgtat
    48301 ttagatgcgc ataaacatca accgaaaatc gaagtaaccg agaccggttc atggctcgat
    48361 attcgattcg atgtgacagg gatagaggag caagaaatcg atcatgtcct gcaaagcttg
    48421 ctgagaaatg atgcttttta tacattagaa aatggtcagg ttctttcttt tgattcagaa
    48481 gaatttcaac aaacaagcca agtgttgcaa caattacggg aatcgatacg tacagaagaa
    48541 ggaacgatcc atgtacctaa aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc
    48601 aatgctactt ttagtgaatc gttccaaacg atggtacaag atctcattca tccagaaaga
    48661 taccaggcac agcttcccaa aggattgaat gcaacgatga gagattatca aaagcaaggt
    48721 tttcgatggt tgaagatgtt aggtcattat cagtttggcg gtattttagc cgatgaaatg
    48781 ggacttggga aaacactaca gacaattgcc tttttacttt cggaaaaaga agaacggaaa
    48841 agcttctctg ctttgatcgt agcgcctgcg agcttaattt acaactggca ggcagaggtg
    48901 agaaaattcg ccccttcttt aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa
    48961 gaattactgg ctaaagacac agatatccga gtgacttctt atgccagctt aagacaggat
    49021 ctagctaatt atcagtcgca aaaaattgat tatttgattc ttgatgaggc acaaatggtc
    49081 aaaaatagca gtacgaaaac tgcacaagca ttgagagaat tagctgtacc tcagcggttt
    49141 gcactgagtg ggacaccaat cgagaataat ttagaagaat tgtggtcatt gtttgcaacg
    49201 attatgccag gatttttccc gactaaaaca aaattcaggg aacttgccgc agaagaaatt
    49261 gcgcaaatga ttcgaccgtt tattttacgg cgagataaac aaactgtgtt gaaagacttg
    49321 ccggaaaaaa cagagatgaa tctatattct gcacttacag aagaacaaaa aactgtttat
    49381 ttagcttact tgcgtcaaat gcgtgaagaa atcacatcaa tggattctga agcattcaag
    49441 aaaaaccgga tcgggatact tgctggtctg acaagactgc gacaaatttg ctgcgatcct
    49501 cgtctgttta ttgaagatta ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta
    49561 ctggtagctg ccaaagagaa caaacgaaga gttttgctgt tttctcaatt tacagggatg
    49621 ctgactatct tgcaagaaga gttagccgag ctagggatct cgacatttta tttaagaggc
    49681 agtacgaaac cacaagatcg gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat
    49741 gtttttctga tttccttaaa ggctggggga actggattga atctcacggg agcagatacg
    49801 gtcatcttgt atgacctttg gtggaatcct gccattgaag aacaagctgc tggacgtgca
    49861 catcggatcg gacaaaaaaa tgtggtagaa gtgtggcgta tgatctctga aggaacgatt
    49921 gaggaacgca tggattcact ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa
    49981 ggtaatgaag aacagttgac gaaactgact gaagaagaca tccgcatgat tttaagtgta
    50041 ggagaaatcg aggagtaaga gactcgaaaa agcgttcagt aatgggtaag aaagcctttc
    50101 taaagaagcg attgtttatt tgatttaaaa aatagcaagg aggctgggat tccattttat
    50161 cccagcttcc ttgctatcat ttttttattt ctatttttaa aggttataca aagattgtct
    50221 tcattgtctc taacagctga tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt
    50281 caattttgcg ttctcgatgg ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta
    50341 gaacatcatt gtcgtaatta tcgccaacgt ataaggtctc ttctggaagc atatgaaatt
    50401 ctttctcagc cagctgaaaa atctcttttt ctggtttttg gaaacctgtt gcttgagaaa
    50461 tgagcatatt gcgggaagga atccaattgt tcaattgaag ttgcttcagt ttttttgtct
    50521 gatggtcagt cggcccattt gtgataattc ctaatgggac attcttttcc ttcaagaaat
    50581 cgagggtttt tttgacctcc tcatgcaagc agatattatc aagttcttcc tcgtaaattt
    50641 tttgaaataa gaggccatct tcttccgtaa tatgagggta gtctaaatct tttagtgatt
    50701 ggctgatccg atgtgctcgc atatattcta gtgtccaatc tcctgccatt acttttggga
    50761 agttttcatc actatgatgg cggaaccgga tatatagtgg atgcatatct gcatctgaaa
    50821 caagcggaac gactcttttg accgcgtttc gaaatggctg ctgctgatca tacatcgtat
    50881 catcaacatc aaacacaact gatttaatca aaattttaca cgcctttcgg ttttcattga
    50941 ttttttcaca aatccttgac tattgtaaca gaaaaaattg tctaaaaaag ctgataaata
    51001 aaggtttttc ttactatatt tctatttcct tgacagaata aggtttttat atttcagttt
    51061 ttttcactaa aaatcgtgaa acacgtcaat aagtttgatg aacaaattaa tcattatggt
    51121 agaagtcgat tgatttattt taatgcaatc tctgtggaat tttcgaaaga tttatttttt
    51181 taatacagtc tcaatataac tattcaaaca taaaataacg ttatttgatt tatttgttta
    51241 tagt
//
LOCUS       DAFTHM010000009        47773 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFTHM010000009 DAFTHM010000000
VERSION     DAFTHM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.009"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(38..1189)
                     /locus_tag="L7C88_000557"
     CDS             complement(38..1189)
                     /locus_tag="L7C88_000557"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBP9557413.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="L7C88_000558"
     CDS             complement(1202..1639)
                     /locus_tag="L7C88_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBP9557414.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="L7C88_000559"
     CDS             complement(1654..3420)
                     /locus_tag="L7C88_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBP9557415.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="L7C88_000560"
     CDS             3684..4361
                     /locus_tag="L7C88_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557416.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="L7C88_000561"
     CDS             4364..5491
                     /locus_tag="L7C88_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557417.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="L7C88_000562"
     CDS             complement(5691..6131)
                     /locus_tag="L7C88_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBP9557418.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="L7C88_000563"
     CDS             complement(6142..8175)
                     /locus_tag="L7C88_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBP9557419.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="L7C88_000564"
     CDS             complement(8177..9880)
                     /locus_tag="L7C88_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBP9557420.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="L7C88_000565"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="L7C88_000565"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBP9557421.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="L7C88_000566"
     CDS             complement(10963..11988)
                     /locus_tag="L7C88_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBP9557422.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12197..13066)
                     /locus_tag="L7C88_000567"
     CDS             complement(12197..13066)
                     /locus_tag="L7C88_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBP9557423.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="L7C88_000568"
     CDS             complement(13525..15417)
                     /locus_tag="L7C88_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557424.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="L7C88_000569"
     CDS             complement(15414..17141)
                     /locus_tag="L7C88_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557425.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="L7C88_000570"
     CDS             complement(17157..17807)
                     /locus_tag="L7C88_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBP9557426.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="L7C88_000571"
     CDS             18011..18307
                     /locus_tag="L7C88_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBP9557427.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18479..19099
                     /locus_tag="L7C88_000572"
     CDS             18479..19099
                     /locus_tag="L7C88_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBP9557428.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="L7C88_000573"
     CDS             complement(19191..20357)
                     /locus_tag="L7C88_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBP9557429.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="L7C88_000574"
     CDS             complement(20369..20722)
                     /locus_tag="L7C88_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBP9557430.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="L7C88_000575"
     CDS             20850..21872
                     /locus_tag="L7C88_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBP9557431.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21891..22052
                     /locus_tag="L7C88_000576"
     CDS             21891..22052
                     /locus_tag="L7C88_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557432.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22311..22745)
                     /locus_tag="L7C88_000577"
     CDS             complement(22311..22745)
                     /locus_tag="L7C88_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557433.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="L7C88_000578"
     CDS             complement(22855..24714)
                     /locus_tag="L7C88_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBP9557434.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(24832..25992)
                     /locus_tag="L7C88_000579"
     CDS             complement(24832..25992)
                     /locus_tag="L7C88_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBP9557435.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27723)
                     /gene="araA"
                     /locus_tag="L7C88_000580"
     CDS             complement(26299..27723)
                     /gene="araA"
                     /locus_tag="L7C88_000580"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBP9557436.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27739..28437)
                     /locus_tag="L7C88_000581"
     CDS             complement(27739..28437)
                     /locus_tag="L7C88_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBP9557437.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28394..30055)
                     /locus_tag="L7C88_000582"
     CDS             complement(28394..30055)
                     /locus_tag="L7C88_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBP9557438.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30273..31673
                     /locus_tag="L7C88_000583"
     CDS             30273..31673
                     /locus_tag="L7C88_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBP9557439.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31925..33004)
                     /locus_tag="L7C88_000584"
     CDS             complement(31925..33004)
                     /locus_tag="L7C88_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBP9557440.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33090..34049)
                     /locus_tag="L7C88_000585"
     CDS             complement(33090..34049)
                     /locus_tag="L7C88_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBP9557441.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34061..35572)
                     /locus_tag="L7C88_000586"
     CDS             complement(34061..35572)
                     /locus_tag="L7C88_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBP9557442.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35594..36157)
                     /locus_tag="L7C88_000587"
     CDS             complement(35594..36157)
                     /locus_tag="L7C88_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBP9557443.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36163..37026)
                     /locus_tag="L7C88_000588"
     CDS             complement(36163..37026)
                     /locus_tag="L7C88_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9557444.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37040..37936)
                     /locus_tag="L7C88_000589"
     CDS             complement(37040..37936)
                     /locus_tag="L7C88_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9557445.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38111..39400)
                     /locus_tag="L7C88_000590"
     CDS             complement(38111..39400)
                     /locus_tag="L7C88_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBP9557446.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39372..40889)
                     /locus_tag="L7C88_000591"
     CDS             complement(39372..40889)
                     /locus_tag="L7C88_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBP9557447.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41087..41977
                     /locus_tag="L7C88_000592"
     CDS             41087..41977
                     /locus_tag="L7C88_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBP9557448.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="L7C88_000593"
     CDS             complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="L7C88_000593"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBP9557449.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42886..44358)
                     /locus_tag="L7C88_000594"
     CDS             complement(42886..44358)
                     /locus_tag="L7C88_000594"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBP9557450.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44995..45357)
                     /locus_tag="L7C88_000595"
     CDS             complement(44995..45357)
                     /locus_tag="L7C88_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBP9557451.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45580..46332
                     /locus_tag="L7C88_000596"
     CDS             45580..46332
                     /locus_tag="L7C88_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBP9557452.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46472..47395)
                     /locus_tag="L7C88_000597"
     CDS             complement(46472..47395)
                     /locus_tag="L7C88_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9557453.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47410..47682)
                     /locus_tag="L7C88_000598"
     CDS             complement(47410..47682)
                     /locus_tag="L7C88_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557454.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        13901 a         9936 c         8252 g        15684 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgc
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttattat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaactttc attataggct actgcaacat ccatccaatc
    27241 agcaatctct ttttggatct caggtcgttt ccagtagcca acgacgattt tattttgttt
    27301 atttaatcga gcattgatga acccatattc gcggtcacca tgagcggatt gatttaaatt
    27361 catgaaatcc atatcgatcg ttttccaagg aatgctttcg ttatattgcg tagctaaatg
    27421 aagcaatggt ttttgtagaa gctttgtccc gcggatccac atttttgctg gtgagaaagt
    27481 atgcatccaa gtgatcacac ctgctacttc ttctcgataa ttgacctctt tcatgatttt
    27541 tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg attggataag gcaattggcc
    27601 attttcattc agttcatcga ccatttcttg tgcatgtttc tttacttctc gcagtgcttc
    27661 ttccccatat aaatgctgtg atcctacaac aaaccaaaat tctttttctc caatattcaa
    27721 cataattagc cactcctttt atttgttttg tccgtaatac gcattttttc cgtgttttcg
    27781 taaataatgt ttatctaaaa tccgttgagg cagctcttct gaaaatgaat tgagctgtct
    27841 ggtaaataaa ttcatcttgc atacttcatc tagtacgact gcgttcatta ccgcactttg
    27901 cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa agtacccctg gaattgctaa
    27961 gggatcaatt ttgcgttctt tgaatgtttc tatgataact tttcctgttt catattcgta
    28021 cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt
    28081 atctgcatgc gtcgtcccca tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc
    28141 ccatgtcgag tgagtatgga cgattcctcc gatttgagga aatgaacgat ataaaacagc
    28201 atgagtaggc gtatccgaag agggattgag tttaccttca atgatatgat tgtccaagtc
    28261 cacaacgacc atgtcgtctg ctgtcatctc ttcataactg actccgctag gtttgataac
    28321 gaaatatcgt gtttcaggat caaaagcgct cacatttccc catgtatatt tgacgagtcc
    28381 gtgtttaggc aagtcaagat ttgcttggta tacttcttct ttcagttgtt ccagcatttt
    28441 ctatcactcc tttttcttgc aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac
    28501 ggtaacgtct cataaatatc tgatagcctg ctatttcttc tgctgaaggt gtgatggtga
    28561 ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc
    28621 gatccatcat ataggctgct aataacgcga ttccccacgc tccaccttct ccggctgtgt
    28681 ccatcactgt aactggtgcc tccatagcag atgctagaat ccgctgtcca acttctggtg
    28741 ttttaaaaat ccccccatgc cccactaaac gatcaatttg gacattctca gatttcaata
    28801 tatccattcc gattctcatt gcaccaaaag cactggctaa atggatccgc atgaaattcg
    28861 ctaaatcaaa acggctacct ggtgtacgta caaataatgg ccttccttca tttactcctg
    28921 taatgttttc accggaaaaa taaccataag aaagtaatcc cccgcaatcc gtatcgcctt
    28981 ctagcgcttt gttgaataat accgtgaata atttatctct gcttatctcc atacccaaag
    29041 aattggtaaa ttcttcaaaa atactgaccc aagcattgat atccgaagag cagttattcg
    29101 tatgaaccat gcctactagt tctcctgaag gtgtagtgac catgtcgatt tccggatgga
    29161 cattttctag ttctttttct aatacgatca tagcgaaggc ggaagtacca gccgaaatgt
    29221 tccctgtccg tttggctaca ctgttcgtag cgaccatacc ggttcctgca tccccttctg
    29281 gcggacaaac cgggattcct ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg
    29341 attcgcttaa cttgccagct tcttctcctg ctactagaac tttaggcaaa atgtgatcca
    29401 agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa aatatttttc atttcttgat
    29461 ggtaggtttt cgttgaagga tcgataggaa acatgcctga tgcatctcct acgcctagta
    29521 ctttctcacc agtaagctgc caatggacat aacctgcaag cgttgtcaaa aaattaattt
    29581 ctttcacatg ttcttcttta ttcaaaatag attgatacaa atgagcgata ctccatctct
    29641 gcggaatatt gtattgaaat ttttccgtta atattcgttc tgcttcttca gtgattgtat
    29701 ttcgccaagt acgaaatggt actagtaact gttccttgct atcaaatgct agataaccgt
    29761 gcatcattgc actgaaccca atcgacccga ttgtcgtaag attctcgcca tagatttcga
    29821 atacttctgc tgccattttt cggtaactga cgcgcagtcc tttccaaata tcttctaatg
    29881 aataggtcca gataccattt tctagtttgt tttcccactc ataactacca gcggcaatag
    29941 gagtaaaaga tgaatcaatc aatacagctt tgatcctagt tgatccaaac tcaatcccta
    30001 aagatgtacg accatctatg acatctaaca tactttgcgc atttacttcc ttcataatga
    30061 tttaactccc tccttctcgt caaacctgat caaaccgtct ttttagtagc gcttacaatg
    30121 attattgtat acttttgtac gtacatgtca agcggttatt tacaagaata caataaaaaa
    30181 cacttgtttt gtacgtacat aagttataaa atgaaattgc ttacaaaatc tgatcaaccg
    30241 ccttctcgaa attctagaag gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat
    30301 cgtttattta tttttttggc gcatttggcg gcattctatt tggatatgat attggtgtta
    30361 tgaccggcgc cttacctttt ttacagcatg attggggttt ggcaggtaaa gcttctttga
    30421 taggatggat cacgtcttcg gtcatgttag gtgcgatcct tggcggctct ttatctggtc
    30481 ttctttctga taagcttgga cgacgaaaaa tgattcttct ttctgcactt atttttatgg
    30541 ctggttctgt cctttctgca tctgcccctc acaatggttc ttattttctg attgcagcaa
    30601 ggattcttct aggtttagct gttggcgctg catctgccct agttcctgct tatatgtctg
    30661 aaatggctcc tgctagacta aggggaagat tgtcagggat caatcaagtg atgattgctt
    30721 ctggcatgct cctttcctat gttgcagatt atttgctaaa agtgttgcct gaaacgatgg
    30781 cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct gattttattt ttcggtgttt
    30841 tagctctacc agagtcaccg cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa
    30901 gagtattgaa ctatattcgg acaccaaaag aagctgaaca ggaattcgaa caaatccagc
    30961 tgaatgtcaa acaagaaaag acaaccggaa cttcttggca tactttgttt ttagaaaaat
    31021 atcgttcctt agtcattgcc ggtattggtg tagcagtatt ccagcaattt caaggagcta
    31081 atgctatttt ttactatatt ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg
    31141 atgcattgat gtggccgatc atccaaggaa tcattttagt tgctggttct ttgctctttt
    31201 tggttattgc agacaagttc aatcggcgaa ctttattgaa aataggcggt agcgtgatgg
    31261 gactttcatt catcctacca gctgttttag gaactgtact ggatgctcat acaaattcgt
    31321 tgttgattct cttgttttta tgtatttatg tcgcatttta ttcttgcaca tgggctccac
    31381 tgacatgggt aatcataggc gaaatattcc cactagctgt ccgcgggcga gcatctggcc
    31441 tagcctcttc ttttaattgg attggttctt tcctagttgg cttgcttttt cctgtgatga
    31501 ctgcttctat gtctcaagaa atcgttttcg gcatttttgg gatcatctgc tttttagggg
    31561 ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac
    31621 aaagtgcatc taaaaaaact tatcctaaac gtatttctat ccatcattct taaagaggtt
    31681 gtgacagaag tggtcagctt caagaaataa gaaggaaccg cttagtttcc agtcacaagg
    31741 aacaatttca aaaaacagct tctcatgttt gatgaatatt gtgacttgtg accagttggt
    31801 aggagaacac cgtttagtgg agaggtggtg aaagaaacgt tcagccttga gcgatgacaa
    31861 aagctctcac aaacattgcg acgagtaacc gtaggagcaa taagaggcgg taaaaacccg
    31921 tctcttattt ttcgttttct ttcactgttt cccgttcaac tagtacaggt tcatagagaa
    31981 tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc
    32041 ccaacttttc ttttggatgc gtcaatgttg tcaatttttt attccctaaa tggcttaaag
    32101 aagaatcgtc tgttcctacg atcgataggt catctggaat atgatagcca ttttctgtca
    32161 acttatctag cattaaacta gctatttgat cgttatagca aatgatgcca tctaaagctt
    32221 gttcttcttt caaccgttgt actgtttttt cagcgattgt ttctcgtgtt tccgtggtga
    32281 aagtaatgat atcttccgtc aaaaaacgca cattatactg ttcacacgcg ctgataaaac
    32341 ctttcatcct gtattttcct tgaagatcgt cgatttttgt gatgaacaac agacgctgat
    32401 gtcctttttt tatcaaatat tctgctgcca taaaaccgac tttcacatca tctaaacaaa
    32461 tataagaggc atttaactct tcataagcag cattgatcat caccatcgga atgccttgtt
    32521 ctctcaaagc aacataaagt gctaagtttg ggttatactg attacttttc gtaggctcaa
    32581 cgatcaaacc atctacccca taagcaatca ttttcttcaa acactctttc tccaattcgt
    32641 gatcgttatt cgtactggct aaaagcaatg aatacccaga ttctcgtaat tcattttcga
    32701 ttcctcggat aatcgacgga aaaatataat cagagagata tgtggtgatg acaccgatcg
    32761 tttttgttct gttcaatggt gttttttctt tcttatagct gtcatctaca tatgtgcccg
    32821 accctttttc tttacgcaga tagccctcat ttaccaacac agcgattgct tgccgaatcg
    32881 tatgtctgct gacgtcatat atttcttgca gcttgaattc tgagggaatg gttgtattta
    32941 cttcgtattc ctcacgaagg atcttttgtt ttatctcttc tgcaatatct tgatattttg
    33001 ccatttgcct tgcccctttt tatttgtacg tacatatatc ataacgagtc tgcaaggttt
    33061 attcaagcaa aaatcaaggt ttcttgtgct cataaggcat acggaacagg ttcaccaaat
    33121 tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg
    33181 tctaacggat cccctttttg gttcttctct ggtcgagcat gatagatcaa aatatcaaag
    33241 cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac caaattgctt atttttttca
    33301 gaagaaacga atactggctc cgataattta tgccatgatt cttttaataa aagattcttg
    33361 tgctcatcag cccacagcag gcccatggca tagttttcat ctgttgcact accagaatac
    33421 gtaatgaata ttttcccatt gcgagtaagg actgctggac cttcatttac tgaaaaaccc
    33481 cgtttttccc attcatactc aggtatagaa aggaggatct gcttcccctt taacgtccaa
    33541 ggattatcca tttcggatag ataaagatta gaattcccag taatttcagg atcttgttgg
    33601 gcccacacat aatatagctt tccttgagaa gagaaagttg ttccgtctaa actgaaagtt
    33661 tcccttttcg tttttatttg tcccttttct atccaatctg tattcattgg atctatatgc
    33721 tgattttcaa gtacgaacat gcggtgatga tgagattcat cacgtatagt tttatgattg
    33781 cttgcagcaa agtaaatata ccattttcca ttgatataat ggacttcagg tgcccagatc
    33841 aattcactca tcggtccttc ttcatgagcc tgccatacaa tcaggcttgc agcatgttct
    33901 aattcattca gtgactttgc ccttcttaat tcaatcactt ggtagcctgg aaccgatcct
    33961 gtaaaataat aataaccatc tgtatgttta tatacccaag gatctgcccg ttgccgaacg
    34021 ataggattat tataaagtgt cttcatcata acaaatttcc tcacattttc tttattctaa
    34081 ttacattcca agagtatttt tctatcccta catttaattc gtcatgtttt tctattgaaa
    34141 aatagtttat ttcaggtttt attttttctg gttcttcacg tgtatttttg tccaacagat
    34201 cgctactggt taatgtgtag tgctctcctt gatctagcaa attgaaatca tgttcaatcg
    34261 ttatcttttg ttgttcattt gtgcgattga tcaagaaaat agtcagctga ttgccgttat
    34321 ctacgatcac actgtccaca taaggaacat tttttatctt ttcacaatca taaacagggc
    34381 aaatgatttg ttgtttcaat acttgacctt tagcatattt cgataagtgt tgcatcacat
    34441 aataagttgg attcctccat gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt
    34501 ttactaacaa tgattgacaa ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc
    34561 ctaatgaacc aaataataat gtatcttcca tagtaaagta acaccaatcg atgggactac
    34621 cgacttcaaa atccctatgt cttttttccg gttgggcatg tacattccat tcatcaaacg
    34681 ctagatacat tgttttctca cttctcaaat atccttttac ataatcacaa gtagcaacga
    34741 tttcttcaat ttgacgatcg aatcgataag cttttgcaag gtatgtcgct gtatcatcac
    34801 gctcattttt aggaggttta gtcaagtctt cttcatcata cttatcaata tagttatgca
    34861 aagctaaata atctacattc tcataagctt cttctaatgc gatacgatcc cattcagggt
    34921 acgatggtaa acgtggcgta gagcttccaa ctaagattgt ttcaattgaa tcatccacta
    34981 acttcatgac ttttgaggct tcatttgcta acctaccata ttcataagca ctcttagccc
    35041 ccacttgcca tggaccgtct agctcattcc ctaaacacca taatttaacg ccaaaaggct
    35101 ttttttgccc attttttatt cttaaatcac tccagaaggt tccttttgga aaattacaat
    35161 attctactaa attttttgct tcatcaattc cttttgttcc taaattcacc gtgaatatcg
    35221 gtttcgcttg tacatgactg atccatttaa aaaattcgtg gagtccaaaa gaatttggtt
    35281 ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg ttctttccta cctacagtat
    35341 ccacccaatc ataaccagat gtaaagtttc ctccaggata gcgaatgaca cctaattcta
    35401 attcctttac ataagagagg acatcttgtc taaacccgtc accatcagct gtttcatggc
    35461 ccggttcata aatccctgta tagacgacac ttcccatatg ctcaacaaat gagccaaaca
    35521 gccgagaact gatctctcct accgtaaaat cctctctgat ttttactttc acttcttcgt
    35581 ccaacagctt tccctacctt tcatttccta tagtcaagat aatagataca agtttccata
    35641 cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa tatgagcagt acaaatccta
    35701 ataacaatac gcaacaaaga atatttctca aaaaatcaaa aaatactttc catgcacttt
    35761 gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga aatcacatat atccaggata
    35821 aaagaaacat ggaataaata agtaaaacta catatccact aattgaaagt acgattgtct
    35881 gttcttctaa taattgatta acaagaaaat aaataatgat cgttaacaga ctaaggaaca
    35941 agttcttacc aaaatgttgc tttattcctt gaaagaaaaa ataaatgata tttcctgatc
    36001 cctcaccttt ccattgcgcc attacataaa aaacagcaca tgtagcaggc acgatagtaa
    36061 taacaggcaa acacacgatt acccagagaa tacctaataa gatgtaatca gaaaccacaa
    36121 tcaactgtcc ataaaattta gtctcaacta ttttcatctt cctcactctt tcattccaga
    36181 catagctgtt ccttgaacaa aatatttctg tgcaaaaata taaaccacta gtaatggcag
    36241 cattgaaata accgttccag ccattacagg tccataaaaa gaaatgttct gccctgtaaa
    36301 taaagctaac cctgctggta aagttctcat ttttgaacta cttgtcaata tcaatggata
    36361 aagcaagtca ttccaactat tcatcagcgt gaaaatccct aatgataaaa gagtaggttt
    36421 gctcaatggc aacatgattt tcaaaaaaat attaaactca cttaatccat caatgcgtgc
    36481 tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa
    36541 tgcagttgtc atacgaggaa tgatcaaacc tgcataagta tcaagcatgc caagcaaatt
    36601 gacttcaata aatagaggaa tcatgaagac ttggaatggg atcatcattg tcagcaaaac
    36661 gaaatagaac aaaactgatt ttcctttgaa acgcatacga gcaaatgcat accccgcaag
    36721 agaatcaaag aatacagaag tgatcactgt ccctccagca aaaatcactg tatttttgat
    36781 gtaatctaat aaagggatcg ttgtccaaac cttaatatag ttatctaggg tatagctatc
    36841 tgcaaatatt ctaggcggaa atgagataat gtctttttcg tgtttaaaag aagaaataat
    36901 cagccacaaa aaaggaaacg caataaccaa caatataact agcatactaa tcgttcgaat
    36961 gattttttta ccactaactg cttttcgact attcacagta actgtaatcg agctttctgg
    37021 tgccatacag gtttccctcc tatttcattt gtttttcttt ccgtgacatg tacacattag
    37081 tggagatagc tatagttgca acaatgataa acaaaaccga agacagtgct gatgcatagc
    37141 ccaattcata aggtgctgta aatcctcgac tgtaaatata ttgaacagct gtttctgtct
    37201 taaattgtgg gccaccagcg gttgcaacat atacttggtc aaacacttgc atcgaaccaa
    37261 tcagattcgt taaaatacaa aaacctaagg agggaacgat ctgaggtagc gtaatgttaa
    37321 aaaactgctg tcgatttgtt gcaccatcca tttgagcaga ttcatacaaa gagggagaga
    37381 ttccctgaat agcagtcaag agaatcgtca tagtaacacc aaaattcttc caaacagtca
    37441 tgatggctac cgtcggcata gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc
    37501 cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa
    37561 taatcgcaat tgacgtcaat gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac
    37621 gattgaatct ggtattttta gataatgcta ctgctgctaa taaaccaacg ataatttgtg
    37681 ttggcgtttc gagtacggtg aaatataaag aatgaatcaa cgaattaact gctcgttcat
    37741 cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat
    37801 tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg tatgacagta aataataata
    37861 aaactaaaaa agatggagtt aaaaacaaat acgcagcacg atcaggacga ttccaatatt
    37921 tggtgaatcc gttcatatag tccacctcat ctttcatttt gataaaatat acaatcttgg
    37981 tttaaacgaa tctgaataag atatccgaac aatcgctgtg atttttgcaa taacacctat
    38041 ctgcaaatac taggtcgatc attcagatat ctgtatcttg ccaacagtct atcctgtata
    38101 aagttctgta ctatttttgc agtaattgat tgatggcatc atctgcatcg ttcatgagtg
    38161 tctcaggatc ttctcctgct aataattttt caatcagtgg attgatgata tcgttattga
    38221 tcgcagagat ttgggtaaaa cctggtaaat atggctctgc atagtccatt tgtttcgata
    38281 attcagatac aataggatca ttttttactt cttcatcttt tgctactgaa tccaagtagg
    38341 caggaaaacc attttcgata ctccattttt taccaatttc agttgtattc caatatttca
    38401 aaaactcata gacagcttct tttttattat tatctgtact tgccggaatg gcatatccta
    38461 cgccatctaa aatagctgtt tttttgtctg aatcactccc ttgtggtaag gtagtcacat
    38521 tataatcaat ctcgtttgct ttcaatccgt tatttaacca tggcccattg atttcaatgg
    38581 ctagttgacc agcattcatt aaattgtcca tttcggcgcc agaaatcgat tctggaccag
    38641 tcttgtctac atggatcatt ttttggatcg cttttaacgt tttaaggttc tcaggagacg
    38701 caaattcaga cttagtataa tcatcgttca ctaatttacc gccatttgct aacatccagt
    38761 tatataacgg tgcagttcca tccttattga agacaaaacc tgatacattt ttactactat
    38821 cagttaattt tggtgccatt tctgtcaatt cttcccaagt agtaggtggt tgttcagtat
    38881 ctaatccagc ttgtttaaac aaatcattat tccaatacat atacatgcct tgtacctgca
    38941 tggggacaaa atactgttta ccttctactt cacctaattc aatagccgtt tctttaaaat
    39001 cagatttatc tactccatca tattcccaga aatcgtctaa tggttgtacc gctccgtttt
    39061 ctacatactg tgcaaaatct ggataattta atgcaataaa gtcaggtgct tttttagaag
    39121 aaatcgctgt aggaagtttt tcattcaaat tggcccaagt catgatatcc atttcaattt
    39181 tgatgttttt atcatttgtt ttattaaatt cattaacgat ttcttgcaat atttcaccat
    39241 cagatgcagt aaacccattc caaaaagtca aagtcacttc tttatcagaa tcagattctg
    39301 ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc agctaccaac aaagagccaa
    39361 ttaaccattt tttacctttc attttttgtt cctccttcat ctgataaacg acatctgacc
    39421 acattccaag atagcggttt caataaacaa ttgattttcc catcttcagc ttttacattt
    39481 gttgaatgac ttggttttac ttgttcactt ttaggaagat tagttgcttt tgtatcaaat
    39541 ccactcattt cagaaaaatc aatcactccc tctaatgata attcagacaa gtgaacagtt
    39601 agattcattt cttcttctcc acggttaact gcaaatatga caagttcttt gtcatttatt
    39661 acggctatac tttctaaata cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa
    39721 cgaatttgtg ggcttaacac ctctccttgt ccatacacag cagcttgcat aaatggataa
    39781 tagatcgtct gtctccaagc ttctccgttt gtttctgtcc tgattggtgc aataacgttt
    39841 accaattgag caagacaagc aatctttact ctatctgcat gtttcaataa agtgattaat
    39901 agacagccta atagtaatgc atcttcaaaa ttatagttat cttctagtaa aggaggagca
    39961 atctgccaag gcgctgcttg ctcatcttgt tccgctgaat gataccaaat attccattca
    40021 tcaaaggaca ggttgatctg cttcttacta tgtttcttcg ccttgactgt atcgcacatc
    40081 gctgtcactt cagaaatgaa ccgatccatg tctaaggaac gtgcaagata atgagaaaga
    40141 tcattttttt ggttgccata atattgatgc agagacaaat aatctatttg atcgtacgct
    40201 tgatcaagaa ctgttaactc ccaatcacca aatgtaggca tttgccgatt cgaacttccg
    40261 cataaaacca cctcaattga atcatctacg agtttcatcg ccttagccgt ttcctctgct
    40321 aaccgtccat attcttccgc tgttttatgt ccaatctgcc aaggaccgtc catttcattc
    40381 cctaaacacc atgtcttaat tccaaaaggg ctctcttgac cattcgaacg ccttaaatca
    40441 ctccaataag ttcctttagg aaaattacaa tattcgacta aattacgagc tgcatctact
    40501 ccacgagtac ccagattgac agccatattg atttcggccc ccacatgctg acaccagtta
    40561 taaaattcat gaatcccaac ttcattcgtt tcaattgtcc gccaagctaa atccaacctt
    40621 ctaggtctat ttgctatggg cccaatactg tcttcccaac gaaatcctga cacaaaattt
    40681 ccaccaggat atctaatcat gggaatgttc aattctttta ccaagtgaat gacgtcttgg
    40741 cgaaatccac ttttattagc tgatggatga tctggctgat aaatcccttc atatactgct
    40801 cgtcccatat gttcaataaa tgaactgtac aaccgcggat caactttgcc tacacgcttg
    40861 acactactaa tcaacattgt ggcttccata actgacctcc tttaatttat acatgaataa
    40921 tacacctcgt tgaaagcgtt gtcaataata taaatgttaa acttacttat tttttatcga
    40981 ttttaattaa ccaaaatatt aataatgatt aaaacaaata atttaatata acttttatta
    41041 acaaatatgt taatatataa gaaaaacctt ttaagaggtg atatatatgc aactacaaat
    41101 aaacgaagaa tccttaccgg tatatgaagc attagctagt aaaacaagga tcaagatcat
    41161 ccagctactt tccaaaaaaa agatgaatgt caaagatttg gcaaaagaac ttggagtgag
    41221 cagtgctatc acgacgatgc acgtgaaaaa gctagaggaa gcaaacatca tcaaaacaga
    41281 aaaagtagga caacaaaaaa tttcgagcct tcgtgtcgat aaaatcgata ttagttttcc
    41341 agaaaaaata ttcaatgctt ttgatacgaa agaaacatcg atacctattg gtcactatac
    41401 aaattatgca attgaaccaa catgcggttt agctacgatc catgatttta tcgggaaagt
    41461 ggatgaacca cgctatttta tggatcctcg aaggatggat gcccgcattc tctggtttac
    41521 cagcggattt gtcgagtatc aggcacctaa ttttttaaat acagaggata cattggagat
    41581 gttggaagtt tctgtggaaa tttcttctga atttcctttt tcaaatgaca attggccttc
    41641 agatatcact ttcagcctaa atggtgtgga gctaggaaca tggacgagcc ctggagattt
    41701 tgctgatatc cgcggtaaat atacgcctga ttggtatcca gataatctta atcaatacgg
    41761 cttgctgaag acgatccgaa ttaccaaaca cttgacgaat atgaatggag aacccttgtc
    41821 aaacatcacg atcaacgaca tccctaaaga gcaagacact tggcatttgc gaatcgaagt
    41881 gaaagacgat gccaaacatg tggggggctg tactttattt ggtaaaggat tcggtaatta
    41941 cgatcaggat atcaaattaa aagtttacta cagctgatat ttttcttttc tattttataa
    42001 aacaaaaaca gccaatccct atgaagggac ggctgttttt gctttattgt tatttccaga
    42061 aatcatccaa aacggaaatt ggcaaatgtc gtttatgttg tgtcttgttc caccatgctt
    42121 cgattttttc ttgtgcttga gcgggaactt cttttccttc tagataatca tcaatttcat
    42181 tatatgtgac acctagtgcg acttcatctg caatcattgg tttcccatct tcaagatctg
    42241 cagtcggaat ttttgtgtat aatttttccg gtgcattcaa tgcttgaagc aattgtttcc
    42301 cttgtcgttt gtccaaacgg aataatggca aaatgtcggc tccaccatca ccaaatttcg
    42361 tgaagaatcc agtaatgttt tctgcagcat gatctgtccc taatacggct cctgctcttt
    42421 ctccagctac ggcatattgc gtaatcatac gttgacgtgc tttgatattt cctttgttaa
    42481 aatcgctgat tcccacacct gcttcgctta atacttgtac ttgtgcatca acagctggtt
    42541 tgatatttac tcgcagacta acatcgggct ggataaagtc aagagcagct tttgcatctt
    42601 cttcatctgc ttgttcacca taaggaagac gaacagcgat aaattgatag ttttcatctt
    42661 ttgtttcttc acgcatttct tccatcgtta gttgcgccaa acggcctgct aaagtagaat
    42721 cttggccgcc gctgatacct agtacaaaag ttttaagaaa cggatatttt ttcaaatatg
    42781 ctttcataaa gtcaatactt ttacgtattt cttcttttgg atcaattgtt ggtttgacac
    42841 ctaattcatt gataatttct gtctgcaggc tcatttattc tcctcctatg cttctgtatg
    42901 aagttctgct acgctttttt tcattcgttc catgatagcc attttatggt tccagcattc
    42961 agtagacaga tcgactgggt atttttgcgg attcaagtct cgtttatact cttcccatag
    43021 tgaatctaga ttttcttttg tatattcttt gatttcgttt agtgcaggta attcgtaaac
    43081 tctttttcct tcgataaaga tatcttgtaa aactgggcga gctgtaaagt ctcgaacagt
    43141 tttattgata aacgtatgca ctggatggaa catgaagata gcttcttctt ctcgagggtc
    43201 ttcatcccat aatgtcacgt agtctccttc agatttccca tcaaaatttc gagtgatgcg
    43261 ccacacttgt tttttccctg gagtagttac tttttctgca ttgcttgata acttgatcgt
    43321 atccatcatt tttccttcat catcttcgat cgatactagc ttgaatactg caccaagggc
    43381 tggctgatca taggctgtga tcaattttgt cccaacaccc catacatcaa ttttagcttt
    43441 ttgcatcttt aaattcaaaa tcgttgcttc atccaagtca ttcgaagcat agatttttgc
    43501 ttccgtaaat ccggctgcat ctaattgttc ccgaacacgc ttagatatat aggccatatc
    43561 tccactgtcg atgcgtacgc cttggaagtt gattttgtca cctaattctt tcgccacgcg
    43621 aatcgcactt ggcacacctg atttcaacgt atcataagtg tcgactaaga acacgcagtc
    43681 tttatgggtt ttagcgtagg ccataaatgc ttcataatca tttccataag attggactaa
    43741 cgaatgagca tgggtcccgc tagctggtat cccaaatatc ttcccagcac gtacattgct
    43801 tgttgcatct gctccgccga tatatgccgc tctagttccc cagactgctg catccagttc
    43861 ttgtgcccgt ctagttccaa attccaatag tggatcttct ccgatgacag atttgatacg
    43921 agctgctttt gtcgcgatca acgtttggaa attgaccata ttcaacagtg ctgtttctac
    43981 taattggcag tgcgctaaag gcccttccac ttggatcaat ggttcatttg caaaaactag
    44041 ttctccttca cgagcagaac gaactgttgc tttaaattca aaattttgta aatactccaa
    44101 aaaaccttca ggatagactt ctaatccacg caagtaagca atatcggaat cattgaacgt
    44161 cagattctct aaataattga ctaaccgttc caatcctgca aaaaccgcgt atccgtggtt
    44221 aaaaggcatt tctcgaaagt aacattcaaa aacagcatgt aaatcagctc gacctaattc
    44281 ccagtatgtc tgcatcatat tgatttgata tagatccgta tgcagcgtca aactgtcgtc
    44341 tgggtaagta ttattcatct tgtattactc ctcttggcaa gttttcattt cctacccatt
    44401 ataacaaaaa aaattaatag gaaaagaaat cttccatttt ttctgaaaaa gcacatgttt
    44461 tacggatatt tcttgctaaa aatgaactcc atctgctaaa actatccttt cttattggta
    44521 tttaacctaa acgagaaaga atacttattt tattcaatgt atccgagaca cgaagaaatt
    44581 agcgttttct atttttctta cttgataaaa taagtagatt ttcctactac aatcgtagcc
    44641 gttaagatac cgatgattga acaaatataa ccaaatgtct ctacaacata atcaatggca
    44701 aaagtttttg aagcaataat acgtctttcc ttttttgctt cttatcccca aagaaacgga
    44761 tataacttat tatgtattga atttttttgg aaaggcgaat tatgacaaga tataccttgc
    44821 gttgaaaaaa ctcgcggaaa aaatatcaca cgtttttaaa aagatacaaa gtaagaaagc
    44881 agctgtcaat agaatggaaa caaaaatggc gagacatcaa tcagtctcgc cttgtttttt
    44941 attgtataca ttagatatgg agcaggttac cataaagatg attattagtc gttattaaat
    45001 agaatccttc gtattttttt gttctatcac tacaatatct ttatttggac gtttgaattg
    45061 tattccggca cgttctagct cctgtttcac tcctacatgg actttgacat cttctcgtgt
    45121 catttttaaa acgtgatgaa tcgcatagtc gatttcttgc cttgtgattt ttttcttcgt
    45181 attgatcatc acgacttgct ttttatcata tgtgtctacc aatagcagtt gtgttcgatc
    45241 taacgaaaat aatttgtaat aattaatagc cgtattccca aaaaagaatt ccactacttt
    45301 aggataaaat gtcttaatat ttaaattact attcacaggt gtttcgatta gcttcatctc
    45361 attcctcttt tctatatagt cgatttagat ccaatcttaa gttatgttac catctttcct
    45421 agcattaagg aatcggttac aattgaacct ttaaagacaa aaggatttac cttttatcac
    45481 ttaatagtat aacataattt catgagaaaa aaatacaatt ttttcttgac catctcgtta
    45541 cgtaaaggat tatgcttaca tttgtcagga ggaaaaataa tggagtacac aataaagaaa
    45601 atgtcagaga tatcaggagt cagtccgaga accttgcgct tttatgatga gattggactg
    45661 ctaaaaccag ctaggatcaa ttcttcaggt tatcggattt atggcaaaaa agaagtcgat
    45721 cgtctgcaac acatcttatt ttatcgaaca atggcattca agttggatga tatccaagag
    45781 gtcttagaca atccatcttt tgaccaccag aaagctttaa tcaagcatca gcaaatgttg
    45841 ctggaaaaac gggcacaaat cgataccctc ttgacaactg tccaacagac acttgatatg
    45901 tacgaaggag gaagaaaaat gagtgacaaa gaaaaatttg aagggtttaa acaacaaaag
    45961 ttgaaagaaa atgaagaatc ctatggacaa gagattcgac aaaaatacgg aaaaaaaaag
    46021 gttacagcat ccaatgaaaa atggatgaat atggataaag aaacgtatga agaaatgcaa
    46081 actgttgaaa agcagatgtt atttgatctc actctttact taaaagaacc agaagatgaa
    46141 agcttagcag accgtatctt ccaagctcat aagaagtggt tatcttacag ctggcctgaa
    46201 tatcagccaa aagcgcataa aggactagga atgatgtacg aagccgatga acggttcact
    46261 gcatattatg acgagcgaag tggtcatggt gcagcaaaag ctttaaatga aattatccaa
    46321 aaaaaggcgt aatcttttac atgatccaac aaaaaagtac acgtaaaatg acctaataac
    46381 aaaacagcag acacccaagt tagattttta tgctaacttt tggtgtctgc tccattcttt
    46441 cacaagtttt ttcatcctac tttaaatata ttcatcgttg aataaacgta taaggtattt
    46501 tcactttatc ctttttttct gtaagaaaca attgaaatgc catttctccg caagcttcca
    46561 gatggtggtc gatggttggg aaaccaagaa gctcgctgat cagcaaatta tcgcgtccaa
    46621 tcaccactgg tgtcttatct tgcagatagc tttgcaagat gcctgctgca accatatccg
    46681 aatttgtaaa gacaccatca actccaagct ctttaaaaaa gaagcctgct tgttttcctt
    46741 tctctgcatc tatacaatcc caaaaaacaa gtgattcatc aaaagatgga aaaagttgat
    46801 gacatagctg caaagtgatt tttgagttat aacttagcct gccacttcgc cccaacgtga
    46861 tgcccaattg ctttatacct tgctgcttca aataagtaag accttctgta attgattgtt
    46921 ctcgatcaat aaagacacag cttgcctgtt ttcccttgat ttcttcacaa aaaactagag
    46981 gtccatattt ttgatatgcc aataaatcat ctagtgtatt ggcacgagac gtaatgatca
    47041 atccatcgaa agctttagct gcaaattctt caagatacct tcgctctttt tctttctgat
    47101 agcccgtcgg taaaagtgtc actttgtaat cataatcaaa cgctgcttca atgatcccac
    47161 tgatcaactg atcaaaatac ggatgattgg tataaggcag aatcactcca atgcttttcg
    47221 tttttccata acttaactgt ctggcatttg cattagggat ataatcgact tctttcatga
    47281 ccgcaagtat ttctttcctt ttttcctcat ctacatatgg atgtccattg attacacgtg
    47341 aaatagtaga aactgaataa cctgtgagct ttgcgatatc tcgaatgttt gccactgctg
    47401 cttcgccacc tatacaaaaa gattttcttg taaatagtct accacagctg gaccgcattc
    47461 aaaaaactga tacatttttc cttcatgcga aaaactgatc cgctgcccgc cccaatatat
    47521 atcttttgtc aaattttcga tttcattcat tggtatttct tttactatat tcctattcaa
    47581 cccttgaaaa ctgtacaacg ttaatacgga tcccttgaac tcgacaaacg cataaaaata
    47641 attgttcgtt gtgccatctg ttatctctac ataagtattc attgcaagcc ctccttttga
    47701 tactttgagt atagtgtatg aaacgcgtct catagcaagg agtttgtttt gccaaagaaa
    47761 agttttattc ctc
//
LOCUS       DAFTHM010000010        46737 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFTHM010000010 DAFTHM010000000
VERSION     DAFTHM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.010"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(97..1410)
                     /locus_tag="L7C88_000599"
     CDS             complement(97..1410)
                     /locus_tag="L7C88_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBP9557455.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGIAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(1655..1879)
                     /locus_tag="L7C88_000600"
     CDS             complement(1655..1879)
                     /locus_tag="L7C88_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557456.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(1899..2321)
                     /locus_tag="L7C88_000601"
     CDS             complement(1899..2321)
                     /locus_tag="L7C88_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBP9557457.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(2465..3175)
                     /locus_tag="L7C88_000602"
     CDS             complement(2465..3175)
                     /locus_tag="L7C88_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557458.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(3193..3690)
                     /locus_tag="L7C88_000603"
     CDS             complement(3193..3690)
                     /locus_tag="L7C88_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9557459.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(3727..4179)
                     /locus_tag="L7C88_000604"
     CDS             complement(3727..4179)
                     /locus_tag="L7C88_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBP9557460.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(4314..4919)
                     /locus_tag="L7C88_000605"
     CDS             complement(4314..4919)
                     /locus_tag="L7C88_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBP9557461.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(5369..5989)
                     /locus_tag="L7C88_000606"
     CDS             complement(5369..5989)
                     /locus_tag="L7C88_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9557462.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLCQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(5991..6860)
                     /locus_tag="L7C88_000607"
     CDS             complement(5991..6860)
                     /locus_tag="L7C88_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBP9557463.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(6883..7290)
                     /locus_tag="L7C88_000608"
     CDS             complement(6883..7290)
                     /locus_tag="L7C88_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBP9557464.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(7309..8598)
                     /locus_tag="L7C88_000609"
     CDS             complement(7309..8598)
                     /locus_tag="L7C88_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9557465.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(8625..8927)
                     /locus_tag="L7C88_000610"
     CDS             complement(8625..8927)
                     /locus_tag="L7C88_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9557466.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(8952..11045)
                     /locus_tag="L7C88_000611"
     CDS             complement(8952..11045)
                     /locus_tag="L7C88_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBP9557467.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKVFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(11534..12298)
                     /locus_tag="L7C88_000612"
     CDS             complement(11534..12298)
                     /locus_tag="L7C88_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBP9557468.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(12409..13278)
                     /gene="mdcB"
                     /locus_tag="L7C88_000613"
     CDS             complement(12409..13278)
                     /gene="mdcB"
                     /locus_tag="L7C88_000613"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBP9557469.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(13303..14379)
                     /locus_tag="L7C88_000614"
     CDS             complement(13303..14379)
                     /locus_tag="L7C88_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBP9557470.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(14403..14996)
                     /locus_tag="L7C88_000615"
     CDS             complement(14403..14996)
                     /locus_tag="L7C88_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBP9557471.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(15000..16676)
                     /gene="mdcD"
                     /locus_tag="L7C88_000616"
     CDS             complement(15000..16676)
                     /gene="mdcD"
                     /locus_tag="L7C88_000616"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBP9557472.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(16666..16965)
                     /locus_tag="L7C88_000617"
     CDS             complement(16666..16965)
                     /locus_tag="L7C88_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBP9557473.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(17067..18713)
                     /gene="mdcA"
                     /locus_tag="L7C88_000618"
     CDS             complement(17067..18713)
                     /gene="mdcA"
                     /locus_tag="L7C88_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HBP9557474.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(18720..19631)
                     /locus_tag="L7C88_000619"
     CDS             complement(18720..19631)
                     /locus_tag="L7C88_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBP9557475.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            19751..20608
                     /locus_tag="L7C88_000620"
     CDS             19751..20608
                     /locus_tag="L7C88_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBP9557476.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(20795..21157)
                     /locus_tag="L7C88_000621"
     CDS             complement(20795..21157)
                     /locus_tag="L7C88_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBP9557477.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            21503..22942
                     /locus_tag="L7C88_000622"
     CDS             21503..22942
                     /locus_tag="L7C88_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557478.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(22949..25501)
                     /locus_tag="L7C88_000623"
     CDS             complement(22949..25501)
                     /locus_tag="L7C88_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBP9557479.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMAFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(25615..26946)
                     /locus_tag="L7C88_000624"
     CDS             complement(25615..26946)
                     /locus_tag="L7C88_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9557480.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(26912..28390)
                     /locus_tag="L7C88_000625"
     CDS             complement(26912..28390)
                     /locus_tag="L7C88_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9557481.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITLLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(28695..30530)
                     /gene="tdc"
                     /locus_tag="L7C88_000626"
     CDS             complement(28695..30530)
                     /gene="tdc"
                     /locus_tag="L7C88_000626"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBP9557482.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            31000..32427
                     /locus_tag="L7C88_000627"
     CDS             31000..32427
                     /locus_tag="L7C88_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557483.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(32519..32884)
                     /locus_tag="L7C88_000628"
     CDS             complement(32519..32884)
                     /locus_tag="L7C88_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBP9557484.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPLDVQNK"
     gene            complement(32881..33246)
                     /locus_tag="L7C88_000629"
     CDS             complement(32881..33246)
                     /locus_tag="L7C88_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBP9557485.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(33438..33686)
                     /locus_tag="L7C88_000630"
     CDS             complement(33438..33686)
                     /locus_tag="L7C88_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557486.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            33685..33813
                     /locus_tag="L7C88_000631"
     CDS             33685..33813
                     /locus_tag="L7C88_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBP9557487.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            33870..35564
                     /locus_tag="L7C88_000632"
     CDS             33870..35564
                     /locus_tag="L7C88_000632"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBP9557488.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            35568..35687
                     /locus_tag="L7C88_000633"
                     /pseudo
     CDS             35568..35687
                     /locus_tag="L7C88_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            36215..37348
                     /locus_tag="L7C88_000634"
     CDS             36215..37348
                     /locus_tag="L7C88_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBP9557489.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            37379..37699
                     /locus_tag="L7C88_000635"
     CDS             37379..37699
                     /locus_tag="L7C88_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBP9557490.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(37728..38192)
                     /locus_tag="L7C88_000636"
     CDS             complement(37728..38192)
                     /locus_tag="L7C88_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9557491.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(38324..39577)
                     /locus_tag="L7C88_000637"
     CDS             complement(38324..39577)
                     /locus_tag="L7C88_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9557492.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(39606..39923)
                     /locus_tag="L7C88_000638"
     CDS             complement(39606..39923)
                     /locus_tag="L7C88_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBP9557493.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIINLYRR
                     LNA"
     gene            complement(39949..40269)
                     /locus_tag="L7C88_000639"
     CDS             complement(39949..40269)
                     /locus_tag="L7C88_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9557494.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(40733..42148)
                     /locus_tag="L7C88_000640"
     CDS             complement(40733..42148)
                     /locus_tag="L7C88_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBP9557495.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(42165..43481)
                     /locus_tag="L7C88_000641"
     CDS             complement(42165..43481)
                     /locus_tag="L7C88_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9557496.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(43631..44329)
                     /locus_tag="L7C88_000642"
     CDS             complement(43631..44329)
                     /locus_tag="L7C88_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBP9557497.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(44618..45574)
                     /locus_tag="L7C88_000643"
     CDS             complement(44618..45574)
                     /locus_tag="L7C88_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBP9557498.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(45687..46520)
                     /gene="msrA"
                     /locus_tag="L7C88_000644"
     CDS             complement(45687..46520)
                     /gene="msrA"
                     /locus_tag="L7C88_000644"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBP9557499.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
BASE COUNT        13920 a         9776 c         7932 g        15109 t
ORIGIN      
        1 ccctcggtat tagctcaaaa aacggcaaaa tataagaaac tattttttcg tttttttctc
       61 taatactcag gccagaacgc tgatttcaca acctctttat ttcacattca atatccacat
      121 gaatcccaca aatacaaaga acagaccata catgattgga gatacttctt ttcctctttt
      181 agctgctaac atggtaattg gatagaagat aaaacctaat gcaatcccat ctgaaatact
      241 ataagtcaaa ggcatgccga tcaagatcaa gaatgaaggg atcgcaatct ctaagtttcc
      301 ccattcgatt tgtcgcaaag attgtgccat caatactcct accataatca atgctggtgc
      361 agttacttgt gaagtaacaa ctgatagtaa tggagaaaag aacaagccta acaagaagaa
      421 aatccctgta gtaatagctg tgatacctga acgtcctcca acggcgatac cagctgatga
      481 ttctacaaat gcaccaacag gagaagtacc aaataaggaa cccgcaagca tagctgttga
      541 atcagaagct aaagctttcc ctacacgagg catcttgttg tctttcatga aacctgcttg
      601 gtttgctaat ccaactaaag ttcctgctgt atcaaagaaa gtcacaagca agaatgtcag
      661 cactacgacc cacatttgaa gagaattgat gtcccctaca tgttttaatg caactaaaaa
      721 tgttggtttc aaacttggtg ctgcggcaac aatttcagaa ggcattggaa tcaaacctgt
      781 gaccagacct aaaatcgttg tagctgctat cccgatgaag atgccacctg gtacacgccg
      841 aacaagcaag atagcagtta cgactaatcc aaaaatcgtc aaccaagtag aaccaacgtt
      901 gagtgatcct aatcctacta atgtagattc attcgaaacg atgatcccac cttcgctcag
      961 accaaggaaa gcgataaata gaccgatacc gccagaaatc gcatatttca aatctgctgg
     1021 gatcgcatca atgatcattt cccgcagctt gaagattgtg atcaaaataa aaatcaaaga
     1081 agcaacgaat acgccggcta atgctgtttc ccatggaatc cccattccta aacaaacaga
     1141 ataagcaaaa aaagcattga tcccaagagc aggtgccgtt ccaattggat aacgggctaa
     1201 tacccccatt aaaacacagc cgatcgcact ggctaatgca gtcgcagtaa acactgctcc
     1261 ttcatccatt ccagaagcac ctaatacagt tggatttaca aataagatat aagccattga
     1321 gataaatgtt gtaaatcctg ccagtacctc acgttttacc gtggtgttca atttttctat
     1381 ttcgaagtag gaaagtattt tttccttcat cttccatccc cctaaatccg aacattataa
     1441 ataaagtccg ttaaaatttc gatttattaa taaaacaacg tgttttatca tatactaaaa
     1501 caaaacataa gtaaacaaaa aattcggatt ttaagcaaaa tccgaacgtt ccatctgatt
     1561 aaatcccttt atctcaaagt tcatgaacat tcactttgga ttacaagaat ttctttattg
     1621 tgttaataaa gtttcttcat tctagtctca aaaatcaata gtgtgatttg attttaccat
     1681 ttcgtttctg ttcttctttg atgaattctt ttgtatcgac aggattcaga ttatttagtc
     1741 cgccaaaacc tgtatcgacc atttttcccc agccttttgt cttctttttt cctgatttga
     1801 gattctttgc tcgaagcttc tcactatgtt ttgctcgccg atacttcaaa taaccttcta
     1861 atcttcccat tagatccact gtttttcctc ctttttattc aatcagacga ctcagctttt
     1921 cctataacaa aataattgcc ttcagggtca gaaaaattga aagtcaagat gccattgtta
     1981 tctgtgattt ctcctggttc ttccatgttc tcgtagatag tttcaaattc atccgtaaaa
     2041 aatactaaag aaggcggtgg tcctaatacc tctggtgaaa acttctgcac aaatactttt
     2101 gggaatacgc ctaattctaa ttcttttgag atgctgagta caatactctt aaattcttct
     2161 ggcaattcga ttgtttcaga aatttctgca ccaatttttt ctacaaagaa tcggcaaatc
     2221 atctctacgt cattgacata aagcatcaca cgtgtttttt gtatcatcat ttgacccttc
     2281 tttctatttg attttctttc ctgtctataa actgattcca ttatatcacg aaagcgcaaa
     2341 caccttgtgt ttgatactat tcaagaaaaa taaagcaata gtttctagga ttgctttcct
     2401 ccacaaactt tttttacaaa aaaaaaaaac ggcaatgaat gccgctcttc ttatttcgat
     2461 tcttttataa ttctgcttct gattcatctt tggttagtgt gtgtctaaca ctagttacgc
     2521 caaatgtttg atcgattttt tccttcaacg cttcgattgc ctgtgcgcca cgtgccgctt
     2581 gttcagcatt gatggattca atgaccagca ccgctgcttg tgtttcttcc gtcagcattg
     2641 ttctttgggc ttcacgccag ttgagacagc gacagatcgc tccttgttca tcatagtaga
     2701 tgatttcttc cggaagtgcc ggagcatcgg aatctgcacc taaaggcagg aatgattcgc
     2761 caccttgggc ttttcctaaa tgcagatttc ctgcgatctt ttcgatatct tctccgccgc
     2821 aaggtacgcc aaaagacaag gaaatactat tatagatatc tacaagcgga ttgattggga
     2881 aaaattcccg ttcttgattt gcacgtttca gtaaagcttc aatagaagaa cgtgcacctt
     2941 ttttagtctt gaatgtggta aatgcctgac gccactgagc aatgacttcg ttttggctga
     3001 atgtttcttc tgtaaggtaa tttcttgctt cttttgctgc ctcattcaat aattgatgat
     3061 acgtttcttc actttctttt gttacgtggt tatcgatacc atttacggat aagatttcga
     3121 tggttgcttc aggaaatact tcccagaaat tggtatccac tattactttt ttcatctgtt
     3181 cacacctctt gattagaata attgcttgat gaatagatag tctgtttggg gatcatctcc
     3241 catataaaaa acatgttcgc tgtatttgat aaatcctttt ttacgataaa aagcgagcgc
     3301 aacatcgttg tgttcccaaa caccgagcca aatggctgtt ttttgctttt cttttgcttt
     3361 ttcaatagct gtatctagta aaaatgtacc gataccttga tgtttaaatt tttttcgtac
     3421 atagattcgc tcgatttcta aaaaatgatc agccatttcc tcagattgac tcgttcctgt
     3481 atttagtttc aggtaacccg caggctcttg atcgatactc actaggaaaa aatcggtttc
     3541 tttatctttt agctcttctg taagtttttc tagtgcataa gcttgtgtca agtaatcagc
     3601 taaatgctcc ggtgaattat cttttccaaa tgtatctgta aatgtttcga tactaatttg
     3661 ttgtagtaag tctacatctg aaggcgtcat ttttcgaatt tcgtatttat tcacggcttc
     3721 ttcctttcaa tagatccttt tattgccttt tttgacaaaa ttccaatctt cgctaacatt
     3781 cttgcatact ttatttaaaa gatattccaa ttgttttgct tcttcgtcag aaagaccatt
     3841 taatgcgact gcattggagt agttgttttc tcgaatgatg aaaggataga tttctgctcc
     3901 ttttttagtc ggatagagtt tcttgatttt tttattttct ttatcttcca aacgttcgat
     3961 catcccattg gattctaatt tcttgattgc tcgggcagtc gttgtacgat ctactttgat
     4021 catttctgct agtttttctt ggatgattcc aggattttcg caaatacgta ctaaataaag
     4081 atactgtcct cttgttaaat cgacttcttt gaattcgata ttgctaatag aatctagcgc
     4141 tcgggcaatc attccgatgt ctcgaaggat ttcagccatt tcatcccacc tttattttgt
     4201 ttgtaagact agtttacctc tttttgttgc aaatgcaact attttcaata aaaaaatcaa
     4261 gttctttttt aataactagt aaagtatatt cttttcttct tttacgaaaa agctcaatca
     4321 caatagatct ggtttttgtt ttctaaaata agtaactgtt tcttcgttgt tcgcttttct
     4381 gatagctttg gcaactcttc tatactaaaa aatcccatgt tggaagtttc attattctca
     4441 ataaacttgg cctcttcacc gtggatcgca caagcaaaaa caagtttata atactgaaaa
     4501 agctgtggaa tatctttttg tttattcgta tcaaaaactg ctcgcaactg agtagtttct
     4561 actgttaatc ctgtttcttc atagacttct ttacgcacat tttcttcagg agacaatcct
     4621 atttcagcaa atccaccagg aagtgaccat tctttcgtcc gtttatcttc gattagtagg
     4681 accttgccat cttttttgat ataggcacga acatctactt ttggtgttgg atgtccttct
     4741 ccaatcgttg tgagcgcttt tatttcttcg aaagtttctt ttcctatttc actgatcagt
     4801 tccaatgaaa tcgtccggat ctcctcaaaa cgctctttat caaatacatc ttttccataa
     4861 tatagaccag cttgagaaag tgcgagtagt cttttgtatt gagccaactt cttgttcatt
     4921 ctcttccctt cttttttagc aaatgtatga ctatgtaatc aagtatagaa gactggttta
     4981 attacggcaa ataaatataa tgaaatctgc aataaataaa agaatgttaa aaaactcgag
     5041 aacaaaagac attcgacttc tctggggctg tgaataaatg gcgttcaaaa gcttgcatct
     5101 gcggtaataa gccccaccaa acgaaaaata tgacgagcta ttcttgtctg gctgttctta
     5161 ttaattgagg caggacagct ttttcacaac ctccccacta aacggtgttc tcctaccaac
     5221 tcctcggtca caagtcacaa tattcatcaa acatgagaag ctgttttttt gaaattgctc
     5281 cttgtgactc ggagctgaac gacaggctca cgacctctcg gtaaacagcg ttcaaaagcc
     5341 aatttttcga tattaagcca tttctttgtt acttattgtc attgatttct ttttctaatt
     5401 tatccaatag tggagtgtaa tccacttgag tatagtctgt tacatcaaat tcatatagtg
     5461 ttcctaactg gaatttgtca tattttcggt cggcgatgat ctttttgaat gcttctttcg
     5521 taatatgatt ggtccctttc gttcgatctt ccaatacgtc accatagtga taatgatcca
     5581 tgatatagct caaatgacga tctgattcac gatcacgttt gtaccgacgt tgacataaca
     5641 cttcaaagtc tgctgttagg cgaatcgtga tcacctgata tccgtatcta tctgctaatt
     5701 cttggagtcg tgctttttgc ttatcactaa aaggatactc ggacacaatc actttctttc
     5761 ctgcttccat atacaaatca agtgctttgt aatagaaagg ataaactttc gtcctttctt
     5821 gttccgcccg ttcttccaaa ttgttaaacc cgatggattc tgcatagtat tccttgattt
     5881 catcgagcgt gatggcatac atatctggaa atcgttcccg tagtttattc ataagatatg
     5941 tttttcctgt accaggacta ccagccagaa gaatgaaata ctttttcatc tcatttattt
     6001 cctaagttaa ttggactttc caagttcata aacagtccaa tcttatgctt gacaatttct
     6061 tttactgctt catttgctgg aatcacatta tggcgaagag acttgttgat ttctgtttca
     6121 ctaaaggttt ctttagctac tttcgtccag ttgactaaaa gctccgttcc aacattgaat
     6181 ttgcggatcc cgttattgat caattcagga taatcttctt ctttcacacc tgttcctcca
     6241 tggataacta gggggacatc aactactgca tcgatttctt tcagcaaggg aatgtttact
     6301 tctgtttttg atttgaattg tccatgattc gtaccgatag caatagctaa tgcatccacg
     6361 cctgtagctt ctacaaattt cactgcgtct tccggtcttg tatatacctt gtcattttca
     6421 gcgacatgga ttccttcttc tgtaccgccg attgttccaa gttctccttc tacggaaaca
     6481 ccgtgcgcat gggcatattc tactactgct tttgtcttca ggatattttc tttgaaaggc
     6541 agatgggacc catcatacat gacagaagta tatccgctgt cgattgcttc tttgatatca
     6601 tcaaagtctc gggcgtggtc taagtgcaag actgcatcaa ccatttcttc ttctgcaata
     6661 gctgtcatta cattgactaa cacatgcatg ccgatatatt tagcggtatc gacacttgtt
     6721 tgaataatga tcggcgaacc catttctttt gctgcgccta gcatagcagg aagcatttct
     6781 aggttatgcg tattaaaagc tccaactgta aaattcaact cttctgctgt ttttgttact
     6841 tctttcaatg ttgtatacat cttttattgc caccttatct ttttatttgt ttcctttgat
     6901 cgttacttgt tttgcaattt gtcgcatctc atccattttg cccatgtagt aatcgatccc
     6961 ttgatcatca ccagcacgag cagcatctgc acgcttctgg ttatagaggc tcatcagttt
     7021 tttataccca tctccgatcg tctgtttatt ttccaaactc ttttctaaat attggatggc
     7081 ttgatcgttc acatacaatt cagaaaattt aagtccaact tgttcataaa gtttcgctaa
     7141 tttatgctta tcttgggtag tggaaatctc ttgtttcaat tgtgtaatct ctgattgaat
     7201 cttttcggtc gcttctggcg atagggcttt ttcttctttt gccagaactt ttttcggttc
     7261 tttttctttt ttcttaaaaa atccaaacat cattttccct actttcaatt aaaatgcttt
     7321 caaaactggg cttaagatcc aggcatataa gagtgctgcg gctactgtat ctacatcggt
     7381 tgctgtagca ttgatgaatc ccatcgaatt aaagatcgtt actagcaaag cgggcaataa
     7441 tgtaataaag aaaccatgag caataccgcc aatgatcgct cctcggcgtc cgccaactgc
     7501 gttgccaaat atccctgctg tccctccggc aaagaaattg gttagcatac caggtaaaat
     7561 catcgctaag ccgaacatgg gcaaagtaaa catggcaata atcgtaccaa tcgttgtcgt
     7621 aatgaaacct aaaatgacag catttgggct ataaggaaag aaaactggac aatctaaggc
     7681 agggatcgca tcaggaacta atttcatagc tatccctcga aatgccggca cgatttcacc
     7741 taacagtaga cgtacaccag ctagcaatac atacacaccc actacgaatt ggatggcttg
     7801 taaaaaggca aacatgatat agttttgatc tcctgataat tcagaagcga atggttcgcc
     7861 tgcaaataaa acagtgatga tatatagcgg gaccatcacg accatgacag acaaataagt
     7921 atcttgcaga aattcgaaat gtgtcggcaa cttgatatct tcgatcgact ttttattttc
     7981 gcctttctca ccaaaaagct tagcaacacc ggcttcaaat aagtacccga tcgtacaaaa
     8041 atgacctaaa gcaatatcat ttgatccagt gattttacga atgatcggtt gcgctactgc
     8101 cggcatagca atggcgaaac aagctccgat aaaaccaccg accaagatca atacgatccc
     8161 tcgcagaccg gcaaaatagc caaagactgt cgtcatcgtt gccatccata aaattgcttg
     8221 accagttaaa aaaatgtact tccattttgt gaaacgagcc aaaataatat tgaatacaaa
     8281 aatggctaag aacgtcagtg caatatctct acctaaaccc aaatcattca ttgcttgacc
     8341 attgatagat tcaatagaag ggatgatccc ttgcatatga aatccttcag taaagatttt
     8401 cccgaaataa gttaaacttc caacgatgat gctcgaaccg gcactcaaca cttgaaatcc
     8461 taggagtgtc tttaacgtgc cagagatgac ttgtcctgct gatttcttct gcagtagtag
     8521 acccaacata gcaatcaatg caatggtgat cgatgcctga gtcaaaatat tttcgatgat
     8581 aaaattgata acgcccatgt ttttaccctc ttttcttttt gtatttagat aactccctta
     8641 tcttgcagaa ctggggtgat tttttcttca atttcatttt ttgaaacaat atttttcaaa
     8701 tagatcatcg ccgttttagg atcaactgcg aacttttcga actgcgaacg aaaattttct
     8761 gctgtgatga tcacatctgg tttcatggaa actgcggaag aaatatcaca atggtccagt
     8821 ttggcttcta ctcctaattt gttcaaaaca tcctcagcag acatctgtgc tgcaaaacta
     8881 cttcctaaac ctgcaccgca tacgaataaa atgttcaatt tgttcatctt tgttctcccc
     8941 cgtatcattt attatttctc aactactgaa aaaagcagtt gtttgaaatc ttcgatattt
     9001 gtgcattcaa tcaatcgatc caacttctct tcgttgttga tcaattcaat tagttctttc
     9061 atgatgttca gatgcgagta ggagtctact gctgccaaac aaaaaataat ctttactgga
     9121 tccatttcag gattaccgaa atcgattggt tgctcaatcg tagctacgct gactcctaat
     9181 ttattgaccc catcttctgg tcgggcatgg gctagtgcca tgtgtttgcc aatcacgata
     9241 tacggtccgt aatcattcac tgcacgaatc atcgcttcga catagcgctc ttcgacaatg
     9301 ttttctttaa ccaatggtct agcagctagt tcaatcgatt cctcccaagt agtggctttt
     9361 tctttgatca tgatattgct gtccgtcaaa atatctttta acataggctg gatctccctt
     9421 ttgttgattt ctaaattgtt tgtttcgaat aatttttcta acttgccata gatgattcga
     9481 tctactcggc caccactttc tttcatgaca tctattattt gagtgaataa ctccgtcgat
     9541 tcatgactgt taggctctaa ccgctgtagt tcttcatttc ttttcaaaaa gtcttctata
     9601 accaagatat tcgtctcagt taaaatcgga tcgacaacta aaagcggctt atttcgataa
     9661 ttcaattgaa aggtgctgaa aaccagattg acatccaatt tatctactaa ttcgatttct
     9721 tttgaactta aaactgcagt aatctcgatc tgaggaaact tttctttcag attctctgct
     9781 aacagatttc cagtagccat cccatggtta cagacaacga ctgatttata aacataattc
     9841 aagtctcgct tgattacact ggcgatcgtc gaaaagtgga tgacaagaaa agctatctcg
     9901 tcctccagta tcttgccacc aattacttct tcgatcgtag gaacaaaatg agtgactgcg
     9961 cggtagattg ggaaataatt tgttcggatg ttttctttca atggattcat gacttggata
    10021 tgattcttga ttcttacaat cagtgcagcc atgtgcttat agagattttc gaataaagct
    10081 tcttccttta gatggaaagg tacgtgtgtc tcgttctcta caaattggat caattggatc
    10141 gttagtaatt gagcttgtac ccactcgatt gaattggaga tatctctagc attgaacgtc
    10201 tcaatagtga aacgaagata atttctttct acttgcggga cattgtccaa ttgaaattcc
    10261 tcgatcatgt ggtcaataaa tgcagaaaag ctactgtctt ttatttctgt atttttccaa
    10321 ttaatggcag agataaattc atgtttcctg attcgctgga tccagatcaa tgtaaaaagc
    10381 aggatttgtt ttttataaat atcatcttct tgtttcaaca acttattgga atagatctcc
    10441 tgtatttttt tgatttccac caaaggaaaa taatggagaa agattttttg agccggtgtt
    10501 aattgtgcat cttgattcat aaagaagtcg gtcattccca gattctgatt gataaaatca
    10561 tagatcatcg tacggataga tcgttctgaa cctttataaa ccagtccttg ctttccataa
    10621 ctgacgatct ctatcccata actgaccagt gttgctcgta accgtctcat atcttcatct
    10681 aatgtacttt tagagatttg aaattcttct tcttttttgt ttagatggat cgggattcgg
    10741 ctgtaagcaa cggctaaaac tagatcaaaa atacgttcgc gccgattcaa aaagccgtct
    10801 ttcacatctt ttatttcagt ttctaatcga gcttgctttt ccttttccag cttcaacaaa
    10861 aaaactttgt tgcgaattgt acggatctcc ggaagctttt tactgctcaa ccagatattc
    10921 gcttcaagaa cttcctgacg gatcgtccgc tgactgacat tgaactcact tgctagatgt
    10981 tttgctttta ctggatattg ggctgtcatg attctgtgaa gtatttcaat tgttcttgtt
    11041 ttcatagaaa tgatctcctt ctgatttcaa gtatatggtt ccgcttacat aataaaaagt
    11101 agatatttct gccacttgaa gtggaaagaa agtaagcaaa gcaaacaaaa aataagccat
    11161 atgctttttc atctcctcaa cgaaaaagac atacgcctat tattacaaaa attttgccca
    11221 tctatacaaa aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacaactaaa
    11281 ctaaaatagt gcttcctatt tttcgtttgg ttgttcttat tatcgcagat gcaagctttt
    11341 aaacaccatt tagtggagag gttgtgacag agatgttcag ccttgagcga taagaagcga
    11401 ttttgaaaaa tcgcttccca tattttacaa aatcgtgcct tattgccgat aggctatctc
    11461 tggcacactg tttattcaga aaaaggagct gcgacaaggc ttttgtcaca actccgttca
    11521 taaatatttc ctgtcaatcc agcataatcg gctgaataaa atcggcttgc catctttttt
    11581 ctttctcaga aaaatcaaaa taccatatct gagaaaaata ctgtcgttgt gtcttacttc
    11641 ctgagatcaa tcgcccatct tttcgatcga ctgaataatc acagcatctg aaatcaattc
    11701 ggatggcaaa actattttcg tggatctgtc gataatttcc tacttcctga atagttattt
    11761 ttttagtatg atttcttaca ccgtctgctt tgtttttttg cagaactttc tgatgttcgg
    11821 caaacagctt gtctgtataa cagcttctgg ctttttcagg agtttcttct tcccaagcgg
    11881 attggatctt catgaatatc ttttggattt ccagaaactg tgctttcttt tctttagccg
    11941 ttcctgacat gcgggacaat atctccgctt tcagcctttt cttttgtctt ttattcttga
    12001 cgatagaaaa agcagaaacc cctcctactg acaaaacagc taatgcaaga aatcccgttt
    12061 gctcataact agaaggacct gtacctggac cataataccc ataagaatct ctgccgtaag
    12121 aacgactgcc aaaataactg cccccatatg aacgaccacc aaatgaacct ctgcccgaac
    12181 ttcgaccgct agatgtacct ccaccatgac cacccgcgac agcgaatcct tgggtcggca
    12241 gagcaaacaa acataggccc actaacaaaa tgattgctaa ataattgatt tttttcattg
    12301 tcttcctcgt tatcttttat tacaaaaaac tatttttatg atagccttgc taaaaggaag
    12361 agtcaataac cagatgcata aactgttttt ttagcaattt tgtcttattt agtcattgag
    12421 taacatcgga caaatgtatg tgtcggcagt ccataattcc tctatcttca gcatgaacaa
    12481 gcttgcagac aagagatctg cgcttcctcc aggagagatt tggttttcct gacaaaagtg
    12541 caacagtgct gtaaatggac gatttggtaa agcactttga ctagcagcat gagcaagttt
    12601 ttgcatttcc actaacgttt tctgatcact gcgatgcaat acgcatgtgt catctagcga
    12661 actcatcaaa actaacaaca tatgcatttg tttctgtaca tatgaatcat tatctagctc
    12721 cttagctgct tggattgcaa gcctgatatg cggataccct aatatcgctt cttcatatgc
    12781 accatttacg ccatattttt gcttcaccct atgaccatga gtggtttttt tatgacgata
    12841 ttttgtatca ggaaaagcag caagcttgct gacatcatca agtattttcg ataaagaaaa
    12901 aggctgttcc atactgattt tttgtgcaat gacactgatc aatagcccca ttgcccaaat
    12961 cgctccttta tgggtattga tgccatttgt agcaatcagc attgcctttt ccgcttttcg
    13021 cccaatctca gcaattcttt ctcttaactc ctgatcaata gcatgatgcc atgctatttg
    13081 agccatttct tcaaaaaaag gagttagcgt cttagcagac ttaagaaata aagcatagtc
    13141 catatcggaa tgtgcacccg catccagtgc atccactaat ccaggttttg gacttaatgt
    13201 tacttctgcg atcaatgctt cctctaccaa cgcagcgagt tgctgagtca ctgctttttt
    13261 tcgttcgtca tttatcatga cactcactcc ttcttcctac tattacttgc tgaaaccttt
    13321 tttgatagct acccaaatga tatgaagtaa ccagcttaaa gcaaatgcac aacttgccgt
    13381 cattagataa gctacaagaa tcatgactcc tgaaggtaac tgcagccaac tatctttaaa
    13441 caataataac agtacttgga aaacaaatac attggctaaa tacgtacgat aagcataaac
    13501 agacaaccat ttgaacaatg gcaattttgg cgaatcgttt acaatcattt tggaagcgcc
    13561 tatgaagaca gcaaagatga tgactaaact gtataaactt tggatcgtat tcaagtaagg
    13621 tgcattcgca aagctcaagt ctcctggatg tgcgagcaat gaacggacag aaaagaacgc
    13681 gataactaag gcaacaggta agaaaagata acgtactctg tccaaatatt gatagacttt
    13741 ttcgtgataa acaaatgcgg ctaccccata aatcatgaaa ctagcaacaa accgatctaa
    13801 taagtaccag ctgtcatgat aaggcccagt caatacttgt gtttgataga acagatacca
    13861 tgcgacatat aaaatcgttg aaccaatcaa tactggccat acatattttt tattagcaaa
    13921 tactttgtaa ccgagccaaa caaaaaacgg catgaacaat tggatctgca gcatcataac
    13981 ggtataccat aaatgaggcg ctccatcacc tgtgacatat ttcagtaaaa agcttgcagt
    14041 atccgtatac ggagtttgtt gttggactgc tggaaatagc caaagataag ccgtcgtcca
    14101 tagaagatac ggaacgacta gttcaaaaaa cttttctttc aaaaattccc aataagacaa
    14161 atgctgactt gtttttacca tattataaac aattgcaaaa ataaacattg gtgctgtgta
    14221 tttaacgatg acgtaaaagg taccaagaaa agctgtattt gttgcgctgt ggctgtttgc
    14281 caaagcaaag ctcaatatcg tttgcatcat aacagccgtt acagctgata ctttctggaa
    14341 gtcacttacg ttgattttga tttttttgtt ttcaaacatc tctttctctc tctttttctt
    14401 tattaccaaa gttctttggt taatttaggt ccttcgactg ttttcaatag aatttttttc
    14461 tctggctctc tcaaatactc ttttagtgaa aaaccgcctt gccgagtcac tacttgggta
    14521 tcgaattgct caaaaaaagc aggatgcgat tgaattacct gaattggcaa ttcaatcggt
    14581 gaatttgcgt acagcagcaa atcaaaatca ctggtttctt ttactgccgg aatcccagtc
    14641 gataattcaa atcctaagct gccgccgatt ccccatttac atcctgataa tatgtttcta
    14701 gcagcatgaa attgctgata aacaggataa tccatgattt tctcttgtct atacgattct
    14761 tgttcgatga tgtcccacgg atgaatgact tgtttgacgg catgttttga gatttctgtt
    14821 gaccatctct gattgcgggc aggtccacgt aaaccaatcg gtagtatttc tgcgtgatcc
    14881 gtcgacgcac gacgaactgt tccgaacatc ttttcagtta gaacgaccca ttcaggcaag
    14941 gtgaaccctt ctatttcatg tttatcaaaa aggacaatat catgtgcttg aatcattttt
    15001 tatgcatccc attcttcgtc cattttggca cggactttat ttgtttcgac acgtccgaat
    15061 gttttggctg tttcgtttgt gtatcgattt gtcagcatcg tgtcatttgt attgcggaca
    15121 tcttgaatgg cttcattgat tgcttcgatg actttgctga cattttgttc tgaagcagct
    15181 tggtcggtga tatcttctag gaaatgatag atcgctccta gttttgtata attattgata
    15241 tcgtaagcga tagctggaac tttttcagca gctgcttcga tttcagcaac cgaacgtttt
    15301 gtcacacgtg cagcactttc tttagacatc gcttggacgg taatttcttt attgtttaaa
    15361 gcaatcaagc ggcttgattg taatccatgt gctaaaaatg cacctgaaat agcatttcct
    15421 gcaatcaatc caataactgg atgtccagct tgacggagtt ttgcataagc agcagcacta
    15481 ttagccaaag ccacatggat accgatcaat tcttcgttat agccgtatgc ttggcttggt
    15541 acatcgatca caacgatgat tggccgtttc acttttttgt ctttatcttc ttcgtaaacg
    15601 tgatccaaaa tttgtcccat gcggaaacct tcaactaaac caacttcacc gtttcgtaca
    15661 cggtacatcg ggtttttagg atcaggtacg attgatgtca cgatggcttc ttctatgaat
    15721 ttacttgatt taccataata cacagtacta atagaagaag ttggattttt catgccagtt
    15781 agtgccgcaa accaatcgta accaacactt gctgcagctg gttcatttcc ttctgctact
    15841 tctggtaagt caattgattt tgcttgatgg ttagcaattg cttcattgta atcgtcaatg
    15901 gccattggtt ttgaaagatc taaagaatca agtaatgata aataaaatgc tgagctttca
    15961 ctgcgatgcg tgtcttttcg ttcgtccatt gctgcgatga cagcagcttt gattgcttct
    16021 acactatcag tcactaattc atcaatgatt tttgattcta cccgttgacg agatcctaat
    16081 gtattccaaa tcaagtcttt gtcactagaa tcaaattctc gaacgcctgc ttcttgttca
    16141 ataacttctg gtccattcaa accgactctc gctttttttg ttgcgattaa ataactcatt
    16201 aatgctgaag taatcgacat accgccaaat gatcctacac gtcctggaat caaaccgatg
    16261 actggtacat attgttttag agcaatgatt acatttccga tttctgaaat agataacagt
    16321 ccgtagtttg cttcttgcaa acgaacacca cctgtatcta gtacaatgac tggaaagatc
    16381 tcatttcctt ttttattttc ttctaacaca tgttcaagtg cagcaacgat ttttgcaccg
    16441 gaaacttcac cgataccgcc accttggaat tttccttcca tagcgattac tactgcttgt
    16501 ttgccattga tcgtgccacg gctgacaacg atcccgtcat cactttcagg gacgattcct
    16561 tgtgctggta aacttggcgc gatgatttga tcgaatggat caatcaattc acgtccattg
    16621 tcaagtagag cgttcactcg ttctctggcg tttaattcta caaaactatt tttcatctga
    16681 aagttcctcc attgcttgcg tcaatcgtag gtacacaact cctggtgtag caccgaagtc
    16741 attgatcacg atatctgctg aaattggata acgatcaaaa aatctcgtta atacattgtt
    16801 ccatacttcg ccgaagccat cgcttcctgt acaaattttt acagtagatt ctgttttttc
    16861 tgttggaaac atcaagattt ccaaatctcc tgaaccgacc actcctacat ggattttctt
    16921 attgatcggc tgtttcgttg gatatttata agctaattgt tccatggatc tctccccttt
    16981 ttgtaaaaca gagcatacac gttctgctta ttcgtctttc ttcttccatc tgggtaaatg
    17041 gcgacaaaag gtttttctcg ccaattttat gaccaagttc tgaatttcat tggtggttca
    17101 tacaggccat ctgaccattc gatcaaatca tcgatggttt gtgcagctaa taatgaacgt
    17161 ttcgcttcac tacgtttgat gcctagatct tctggtaatt tcacgatgcc ggctgcacgc
    17221 aagctatcta gtgattcttt cgtgctagtc attccaagag gtgtaacacc gccaattgct
    17281 gcaattgctg cttgtcgttc ttcttttgtt tttgctttgt acaaataagc aattccttct
    17341 tctgtcacga tatgtgtagt atcttcgcta taaatcatca ctggtgcatt ggctaagcct
    17401 gcttgttttt gaacagctag tgcatctaat tcttcgacaa agactggttt tttatttgaa
    17461 ccatatgttt caaccatttg aacaactaat ttttggcctt tccctaatgg atcatcattg
    17521 tcgcgaagtg attgccatgc tggtgtagaa tgacgacgac cgccaggatt atgtcccatg
    17581 ttaggcgcac cgccaaaacc agataaacgt ccttttgtta cggtagaaga gtttccttcg
    17641 taatctaatt gcaaggttga accgataaac atatcgatgg catattgtcc tgcagcttgt
    17701 gataatgttc ggttactgcg catcgtgccg tctttaccga caaaaaagac atctgggcga
    17761 gcagcaatat atttttccat accaacttcg ccaccaaaac tatggatgct ttcaacccaa
    17821 cctgattcga tggctggaat catcgttgga tgtgggttca atacccagtt cttcgcgatt
    17881 ttccctttta accctagtga ttcaccataa gttggcagta acaattcgat agctgctgta
    17941 ttgaatccaa taccgtgatt caaagattgt acgccgtgtt ctgcgtagat tcctttgatt
    18001 gccatcattg ccattagaat ttgcaattct gtgatgtttt gaggatctcg tgtgaataaa
    18061 gcttctaatt gataaggttt atctgctttc acgacaacgt ctacccagtc accagggata
    18121 tctacacgtg gtaaagaatc gacaacttcg ttgacttgaa cgatcacgat accatctttg
    18181 aaagctgcag cttcgatgat tgttggtgtt tcttccgtat tgaaacctgt gtacaagttg
    18241 ccgtctttat ctgctttatc tgcagctact aaaacaacat ttggaatcaa atcgatgaat
    18301 aagcgtccat aaagttccaa ataagtatgg atatcaccta atttcattgt gccgtcttca
    18361 atcatttggg cgacacgcaa gctttgtgca ccagcataag agaaatcgat cttgcttgcg
    18421 attccttttt caaaaatatt caaatgttct ggtcgtgaga tactagacat gatcaaatgc
    18481 agatcattca ctttttctgc atctactttt tcaagacttt ctgaaagaaa acttgcttgt
    18541 ttttgattgt cgccttctaa tacaactttg tcgccgggag caatcagttt ttccattact
    18601 tctacgattt tttcagtttc tacatacttg ccattgagca agttgctgat tttttccaat
    18661 cgctgcgctt ttttttcgcg tttagaagcc cagttgcggt ttggtttttc cataattagt
    18721 catctccatt tttgatatag aaacgtggcg tcatcaatac catgttggtc tagattgatc
    18781 gtacggatcc ctttatctac accaaatttt gtatgaatca gctttgtcaa agtattgccg
    18841 gggggaaatt caatcgtcag atccattcct aattcttttg ccaagtccat catttggttc
    18901 cactgcacag ggaaagctag gttttccaac aaatctttac gaatctcttc tgcgtcctga
    18961 gtggctcttc catccgtatt ttttatatac aaacatctag catcagatag atggacagac
    19021 tgcatatacg gcttgaattt cttgaccgta tcattcatca agagacagtg agatggcaca
    19081 gggactttca gcagcttcgc tgtttgcgct tggtgccgtt tggcttctgc caacgtaacg
    19141 gataaacctt cgatactccc agataacgta tgttgcatcg gacaattttc atttgacaga
    19201 taaactggat ggtcaggatc aaatgttttt gctacaattt cctcagcttc gcttctcgtc
    19261 acacctacta ctacgcccat tgcataaccg cttggataag cttctttcat taagactgcg
    19321 cggtgataga ctagttccgc tgcattctca aatctcaaag atcgacaagc aacagctgca
    19381 caaaaagcac caatcgaatg tcctgctgca atatcaggct gaataccgtt tttttccatt
    19441 tcatctaaat aaaatactgc ttttgtcagt aatgctagct ggataaaaac cgtatcttga
    19501 tagttttctt ctttatcaac taaccgatac cccgtcacat tttctaaacg ttccatgtac
    19561 atttcaggga tatccgctaa catccctaac ttctgactgc cttgtccagg aaataagaaa
    19621 cctgtactca tgagcctcgc ctcctcagca cttacttttt ccactgctat cttagtcaat
    19681 ttctgctata ataaaaaatg ccaaaaaaag aaaaaaccat aacaaaaagg tatggatggg
    19741 atggataatt atgaaattgc ttcatctgca gtattttaaa aaagtattcg aaacaaaaaa
    19801 tgttacccaa gcagccaaag aattatttat ttctcaacct gccttgagcc gtgcgatcaa
    19861 acatttggaa aacgaattag gtgtcccttt gttttaccat agcggcagaa acattgagac
    19921 gaccgtttat gcagaagaat tttatccata tgcagtcaag acattagaca cattagaaga
    19981 aggaatcaaa ttattgtctt cggtcaatga gaagatcgtt acttccgtca tattgtattt
    20041 agaggtagcc tctgtttcta ttccgaactt ggtccgaatt tttatggaaa agcatcctga
    20101 tatccaatta acgatcatgc aacatcattt accagatgat attaccgatc ctgtactgta
    20161 catcacttcg gagatgaagc ctggcatgac caatattcct atcatgaaag aacctgttta
    20221 tgtcgccatt cctaagaaac atcctcttgc taaaaaagaa catctgcaat tagaagatat
    20281 ccaacgcacc cccatcttga tgctgtcaaa gagcaacgcc ttccgtcata cactggatgc
    20341 agcacttgaa gcgaaaagta tcgaattgac gatcagttcg acgacagatg atcctgcgac
    20401 attacgttct attgtcaagc aaggattagc tgttagcttt ttcccaaaag tttcttggtc
    20461 ttacgataaa aatgatcctt tcgtcttgcg ggaaatcaaa gatttgccct tgacacgaac
    20521 aatttattta tcttctagct tcacagaaga tcatcctttg atcaaaatga ttgcaaaaac
    20581 gatgcgggaa ttttatttag gaaaataaaa aaaaaagagc tgggacaaaa ttcttgtcgc
    20641 agctcttttt tcgaacaaac ggtgttccag aagtaatttc ttagaaaata agccgaaatt
    20701 tcccaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa gctaaacatt
    20761 tctgtcacaa cctcttctct attgtcctag acattcattg cgttgattta aaacttccat
    20821 caatcaaatc tgctagttca tctagctttt ctattttacg tagatcaata gagatccaat
    20881 gttctttatt catgtgatag gctggaaaat acccctcttt tcctcgcaaa attccgccaa
    20941 gttcaggatc gaccttcaaa tcaagaatat tgatgatcct atggtcactt gcatcatcat
    21001 agattttttc ttctggaaca gacatcagga ccccaaacca ttttttgctt ttttgatgtc
    21061 tgaatacgca ataatcagga aattttttaa aaatatattc tggagacaaa ttgtatgttt
    21121 cattgatgtg atcgattagt tcttttttcg ttagcatctg cttccatctc tttcttattg
    21181 attcgcttta ttcaaagata ccacgtaaga atagaaaaat gaatacaagt agttgctaat
    21241 caaatacttc gatatttttc ttttttatca actcttaaat gttcaatccg cctgtgttgg
    21301 tcttgctacc atctactatt aaaatgttta ttattgtttg cccacctatt ttttgatttt
    21361 agtggtatca tttttcaagt tcatgatgaa attcttatca tcagtaaatg ctccagaaaa
    21421 ataaacaatg attgaaaaat cagttgaaac ttgaccaccg tttattttct ccgtattctt
    21481 agaatagaag ggagtctgat tgatgtattc actaatgaaa aaaatcatta ccgaaaaaga
    21541 tattcgacgt catgtttctt tagtagaaca attgctgaat catacaaaga taaccgtaaa
    21601 tgaattagct gaaatcatag ggacaaccga acgaacgatt ttttctgacc ttcaatctat
    21661 tcgctctcag ctgcccgaag gctgggacat catcagcgat caagcaggaa tcagtttgca
    21721 aaaccagcaa aatttattaa caaatgacct ttgggagatt tttttcaaac aatcagtcag
    21781 tgtcgaactg ctgaaaaatc tgctttttac aaaaaaagtt gctgtccctg attttctagc
    21841 cgaccatggg ctttcttatg ggacattgaa aagacatgtg actaaaatca atcagcgttt
    21901 agcaagttac gacttgcaga tcgatttgac gaaatataca gcttgtattc ttggaaaaga
    21961 gcgtgcgatt cgtacttttt atcatcgatt gctgattcct ttcactcata acaactattt
    22021 tttcgaggat tattcgatcc atgaatccca ttattttcaa tttttaagaa acctcagtca
    22081 aactgaacta gcggttgaaa cagaagagat tttcggaaca tgttggttct ttatcaatac
    22141 gatccgtata aaagcgaatt gccgattaga ttcttctatc cataccaaca gcacactctc
    22201 ctccctgtat gactctgcat tgaaaaaatt gtatttaacg gaaggtattt atcttaaaga
    22261 cactgagctt tcttttgctt ctttctgctt tctggaaagt tggaattaca acaataacta
    22321 tggacaagaa accgctcgct gcctgcatca ttctccattt ttagaggtcc tcgaaacgtt
    22381 tgtagaggaa ctagcttcag agctgtctct tgatcaacta aaaaaaacat ctctgactga
    22441 taacttggct ctcctcatat taaaatatca tgaatcgccg atattgattg aagcattgga
    22501 ccgtcaatac catcgttttt tagaaacata tgatcagcaa tatgcacact tgtatcaaca
    22561 gaaagagaat ttactgaacg atctaaaaaa agaaatagaa atcaatgaac caaattactt
    22621 tctccaactc ttgtctctac tgatccaaca aacgattttt tctatcaaac cgaatttgtt
    22681 caatgtctat tttattttcc aaggagaacc ttcatggaag gcgttcttgc agcaggaatt
    22741 aaaagattac ttaggaaaac gtgtctgctt cttacctatc gaactaaccg atctttccac
    22801 tatttctttt gaaaaaacag atatcttgat ttccaatttc cctctagatt ctctagatat
    22861 ccctattgta tacatttctt ctattccaac gaaaaatgag ctcaatcgtt tgactgaact
    22921 cactttcaaa acttttttat agtaacggct agcgactgta ttctctagct gttttttctt
    22981 ttttgcgaaa cagtttgttc atgatccctt tttctatttc tacaactaag aatagaagaa
    23041 tcacatttgc tccaatcaat aactgttgtg tcatcgttaa acttactgta ccgatcagct
    23101 gctggccgac tggtagaaaa ataaccatcc cttgcaataa agcaaggata cctaatgaaa
    23161 gaaaaagcgc tttgttttgc aaaagacctt ggttcaatga cggcttggac aactctctgc
    23221 aattgatcat gtaaacagct tgagctaaga cgatattttg cagaagaatg gtttgctgta
    23281 agctttgccc ttcaaactgc atagccaata aataggcagg aaccatgatc agtagggaga
    23341 catagatgat ccgaaacaaa tgataaccag ataggattcc ttgctttgga tctcttggtg
    23401 ggcgcttcat gatttctgga tctggcgact cgaaccctag tgcataagat aaagtgattg
    23461 tcgttaccat attgacccat aaaatctgta ctggggacaa aggtagcggg cgattcagca
    23521 taagtgccca aatcaagatc aatccttgag ctaatgcagt tggcaagaag aaattgatgg
    23581 ttttttgcaa attatccaaa atccgccggc cctcttttac ggcttttgca atcgtatgga
    23641 aattatcatc tcctaaaacc atatcagctg cctgtttgct tacttcacta cctttgattc
    23701 ccatagcaat tcctacatcg gatcttttca aagcaggtgc atcatttacg ccgtctccgg
    23761 tcattccgac gatttctcca tttttctgca aagctttaac aattcgcagt ttatgttctg
    23821 gtgtcgttcg agcaaagaca tcgactattg gcacttgctg aatcaactct tcatcagaca
    23881 taagatccaa atcgatccct tctaaaactt tggcagtatg ttttaagcca atttgttccg
    23941 caatcgcttt tgctgtgtct ttgtgatccc ctgtaatcat tttcactgag atccctgctt
    24001 gttggcattc ctttacagct ttgactgcac tttcttttgg cggatcgatc aatccggcga
    24061 tccctgcaaa agttaattgg gttaaagtct catgcgtgag ttcctgtttc gaatctactt
    24121 ttttataagc aaatcctaaa acacgctgac cttttctcgc aaattctgca gctgtctgac
    24181 tccatgcttc ttgttctgca gaagaaagag ttgatttagc aaataatact tctggtgcac
    24241 ctttgacgta aatcaccgct cctttttcct ccgcatgcat cgttgccata tatttgtatt
    24301 cagaactgaa cggaatcttt gcttctattt ttttcaaagg tagattggct gtttctgtgt
    24361 gtcgaatcag cgcaacttct gtcggattgc cacttaaatt ttctgttttc tgttcttctt
    24421 ttgtttttaa ttcctgacag tttttcataa tggacaacac gcaggcttct tcttttgcag
    24481 ctacatccac aactgtcatt tcattttttg tcaatgttcc tgtcttatct gaacagatca
    24541 ctgtcataga acctaatgtt tctaccgaag gaagtccttt gatgatcgcc ttttcttttg
    24601 ccatttcatg tactccaacg gatagaatca tggtcaaaac agctggcaat ccttcgggta
    24661 ccattgacac caccaaagca atcgtagccg aaagaaggat atgccaatcc ataccatatc
    24721 gaaatgtcgt aaaaataact aagaataggc tcaaacaaag aatgccttga aaaatttgtt
    24781 tgtttaatcg gttgattttt ttaatcagag gcgtcgtttg ttgttcgacc gattgcaatg
    24841 cttgattgat tttaccgatt tctgtcgtgt ttcctgtttc tacaacgaca ccgactgcag
    24901 aaccagattg tacaagcgtt cctgaaaaag ccatattttt ctggtcgccg atcgattctt
    24961 cttctgtcaa aacggcatga cttttttcag atgcttctga ttctcccgtc aaaatcgatt
    25021 cttccactaa taaatcatgt gcttcgatta atcggatatc tgctggaacg acatctccgg
    25081 cacgtaagac aatgacatct ccttttacca gttctttcgc agggattttt tcttgcatcc
    25141 cgtttgatag tactatcgct tcttgtccca tcagctgctt caaaccattc aatgattctt
    25201 ccgcttttct ttcttgccag taactaacga gtccattgac gatcactacg aataaaataa
    25261 tacttccttc aatatattca ctagaagcaa atttcaaaaa agaggcaatg atcaacacga
    25321 tcatcagcag atcagtaaaa tgctttgcta tttttttcca tcgttttgtc tgctgccttg
    25381 cttttatttc attatatcct tgatcagtca ggcgtttctg tcgttcttct tgcgacaagc
    25441 cttctgttga tgtttgatag tttttcaata catcttctac cgtcaatctg taccagttca
    25501 tcctatcccc tcctgtttaa ttgatactgt tattatacgc agggaagttt tttcaggcgt
    25561 atcgattatt tcaggggggt ctgaaataat tcgttttgca aaatgtatct gggcctaact
    25621 gatatttcta ttgcttattc ttttatatac aaaatttaag aatacaaacc agataaccaa
    25681 taaaaaagga ataaagcgtg tcgtgctttc gaataacaag ctgaaagcaa ttgaagtaaa
    25741 aaacaccaac aaagcaagat ctttatatct ttgtgtagtg ttccgtttct tttctttaat
    25801 aaattgaaca tgtgcacaca agatcgaaga ccacacaaat agaaaacaac tcgttgtcat
    25861 gcctgccaaa agctgaaaaa acaatcgact atcagctaca aaaaaatgta gacaaagacc
    25921 ggcaaaaaat aacattcctg taattaaaat accgtgtaaa ggtacgcctt tcttagaaag
    25981 cgcacaaaac caatggggca aacttttttc ttttgctgtt tgatataaaa tcctgctagt
    26041 actgtagact gcactatttg ctgaggacaa agaagcaacc aaaatcatta gattgacaat
    26101 tgctgctccg ccttggcaat ggatcacttg cagcatagtc actaaaggac tttcttttaa
    26161 atctaaacaa tgccatggaa caacaaataa aatcgacaaa atcgttccta tatagaaaaa
    26221 gagaatacgc caaggcagac agttgattgc ttttttcaaa ttcttttgcg gatcacttgt
    26281 ctcgccaacg gttaagccga tcatttcaat tccagcaaaa ctgaataaaa ccataggaaa
    26341 tgagactacc attccagcaa agccaaacgg tagtaattca tcgatctgtc caaaattttc
    26401 tttgattccg atagactggg tatgaaaatc tgagacactc aatcctatac ccaataagat
    26461 aaaaaggaaa atccccaaga tcttgatgat tgagaaaaaa gattccaatt caccaaacca
    26521 cttgactgca acaaggttga ctgccattaa gatcattagt gcgctacctc cgcttatcaa
    26581 agctggtaca tgtacaaacc agaaatggat atacaatcct attgctgtta attccgcaag
    26641 tccagctcca agccagcaaa gccaataagt ccaattgaca aaaaatgccc actttttgcc
    26701 taaataatag tcaacgaaat cactgataga gttaaatgta ctatttgcta aaaataaatc
    26761 acccatggcc cgcatcaaac cataaatagc caaaccgcat atcaaataaa cgagaataac
    26821 agctggccct gctgatgcaa ttgcctttgc tgaacctaaa aataatcctg ttccaattgc
    26881 gccacctaat gcgattaact ggatatttcg attagttaga gtccgtttca ttgccggttt
    26941 ttccatcaag ttcacctttt tctttttcaa gcagcatggc gacttcctgt tcccaagaag
    27001 gtttctttat tttttcaata cagagtggta ctacaaacaa aatgacactg atggctgtga
    27061 ctgcaattag attgatccat gttccagctt tcatcgtcag tccgacagaa aatccgattg
    27121 ccgcaaataa aacaataacg acagtccaaa ctccaagatt gctctttttc tctttttttc
    27181 caattctaaa tggtcgattc aactttgcat gtgtataacg caatctcaaa actgcgatcc
    27241 ccatgatgac atagacgata cagtagataa cagtagttga atttacgagc atcaaaaatg
    27301 cttgattgac gccaggaatc agcaaataaa aaagtgcaaa gattgagata atgacagact
    27361 gagtcaaaat aacggatttg gatacgtcaa attgattcgt cttccaaaaa ttgaattttg
    27421 gtggatacgc accttttcta gcactttctg tcactgtctt tgctggtcct gaggcccaag
    27481 cagataattg gactgctaca ccaatgaaga caagtaaact aaacagattc acaataagat
    27541 gtggcaaacc aagaatttgg caataaatcg aaatagattg cgcgatatta ttcaattcca
    27601 tttgtccttt tggtacgaca tttgctacaa ctaaagcatt caaaatattg acgaaaaata
    27661 taaaaattaa cgcggcaaat actccgcgaa tatacgtttt aactggattt tccaatcgag
    27721 tgatatacac agaggacatt tcgataccag taaaaataaa catgatcggc gcaaaataaa
    27781 caaatgagga tgcagtcgta gtatctggta ttaatttgtc ccatgaaaaa ctgcctaatg
    27841 ttccggttgg tacgatccca actttgatcc acgcagcaaa ccctaataag agcatcatcg
    27901 tcaaaggcac gtacaatcct aaccaaacac cgacttttcc gccgattttt gccatatcaa
    27961 atttcaaatt caaaagagtg atgatccaat aaacgactaa aatgacaact aatgtaaatt
    28021 tgctgttcaa accaagcggc acattatcga taatattacc aaacaacgga gcgagtgctg
    28081 aagcgaccat caccatccca ggaaacattt ggacccataa cagccatgag acaacgaacc
    28141 cccatttttt tcctagagca ttcgataccc aaagttctgg accacctttt tggggaaaca
    28201 ttccagcaaa ttcaccagag atcaatgaga ttggaaaagc gtacaataat actgcaacca
    28261 gcatgtaaaa aatcatcgtc cagctcgttg ctgctacatc tggaatattt cgtacacttg
    28321 ctacaagggc gcaggtcatt ccgataaagg tcatggtcgt gatttgcttt gatgaaccag
    28381 tatctttcat ctttattcct tctttcaata gcgacatatg tttttgtttt cttttatttt
    28441 tgttcaagaa cagaaatgac aaggtttcat cgattcagta caaaacccag tatcaccgaa
    28501 acatccattg aacgatctta gtgaactggg tttgatacat gaaacgaacg atccaactta
    28561 tagaacgttt tataaaaaag aatatcttgg cgaggaatat atgaaaaaca gggggaaata
    28621 caattgtttt gatgaagcaa ataattgtct gttctccata tgtctcttgt tattctttca
    28681 cacaaaaatc agttctattg gatgatttcg tttagtttct tttccattgc tttggcgatt
    28741 ttttttgtat aaaaattgaa aattcgatca tcattcaaat aaggagtcat gatagccgca
    28801 cgtagcagag tgattttctg ttcttttttc cattcttctt tcgttagacc cattctttca
    28861 acaaaacgaa tcggagaatc accgtaatct tcttgtgtaa atgtagtatg agaagtaata
    28921 aaccgttcac cataaacatc gccatccata taagaagacc gatcgaacat tttttcattt
    28981 aattcattga tagcgttcaa atctgtacag ccttgttctt tgaataccca attgaccata
    29041 ttaaaatcag gatgattcaa tggatagact tcgattgttt ttcctttaac agtaaaagtc
    29101 agatgatcga gaaattctct gaatctttga gctgcctcga ttgaagcccc aatcaattga
    29161 ccatatccgg tcacattcaa tggcaataca cgatgtgctg tccagactgc ggcggcggtt
    29221 gctccagctt ttgatccttc caaaatataa gctcctaaca tatctggagc ctttactgat
    29281 ttttcaaaca catatggcgc gaaataagaa atgatatttc tcatattttt atgtttgatt
    29341 acgattcctc cagcagcata agggacatag cccatcttat gaggatctat cgtgacagaa
    29401 tccgcttctg aaatagctct gaacccttca tatacctctt tgtcaatcgt tacgcagtgg
    29461 tggaaaacat gatgttcttc aaagaattca gctaaggaag catacggcac aaattctcct
    29521 gcttcgttta gaaacagtga acgcgcatag ccgccatatg cggcatcaac atgtaaatag
    29581 aaatagatcc cttcatcttt taacctttct cttaattgga cgattttatc tacactgtct
    29641 acttgacctt cttctgtcgt tcctacgaca gcaaccacac ctagaattgg gattttttgt
    29701 ccagctaatt cacgaattgt tttttccaaa gcattaatat ccattcgata atcctcttga
    29761 actgggatag caaccatctg atctaagccg actccgcaaa tatctaacgc cttcatccaa
    29821 gaatagtgtt ttgtttgagg gaccagccat ttccctaatc tttggatatt ttttccgcta
    29881 cgggaagaag ctgctttgac ctcatccatt tcttcgtccg taaagctttc ggtcatttcc
    29941 aaaatttctt caacagataa attcaaaagt tcccactcag acattttttt cactttttca
    30001 ggcagcactt ccttgacagc taaaggaatc gatttgatgc aacgggcgta ccataatcct
    30061 tcaagattag caatagaacc atctgctgca atgtgtcccc atccgtctgt catattgaat
    30121 aatgaagcaa aatcctgtcc tacttctgct tccatttgcg aagttgccat agaagattcc
    30181 aatgcaacat tatttgggtt ccacagcatc gcatagttgt aagctaataa agcaggcatc
    30241 aatgtttcag cattcatttg tccccagtaa cggcctgctg aatgccatgg gatcgatcct
    30301 gcgcgtaatc gctgactgac ttcatccaag acctctatca tatggtcgcg ggtggctaga
    30361 taatctggag tgagcttatc tccttcgcta attgcaggca tatctgaagg aatataattt
    30421 tctctccatc caagatgttc atctaccatc ttgttcaaca acattttata aactggtcca
    30481 ttttcagctt tgtcgcctat aaagacggcc ttgatatcca tatctttcat ttttcttccc
    30541 tccatatttt gttggtcaat gtcttgcaga tacatgtgtt tatctgtaac acctcttcac
    30601 tatagcgcca aaaatgagaa attttttttt ataacatcaa atccacgtag atttttacaa
    30661 acaaaaataa ataaagtcgg atttttctga taattcaacg caaaaaagcg aacaattttt
    30721 caataaatca gtcttctaaa atagataacc tacaaaaagc gaacaaacaa ataaaatgac
    30781 tgtccttcat tcactaaaca tatttttatt tttttatatt gttaaaaatt cacaatttat
    30841 tttttaatag aattatctgt tttccaaatt ttataacata aaaaaccttt tttaacggca
    30901 tttatatgct ttttcagaaa ttaactgatg atttcaaaaa gaaaacatgt cataatattt
    30961 cccatattgt gcaaaaaaat acaaggcgga ggctctacta tgattgaaga atatattgag
    31021 aaaaatattt taagacagct gtttttatgt gggcaattct atgtaaataa agaagtcaat
    31081 ctagaaaagc tctccaatct cctgcatgtt tgcaaaacca ctttactcaa tgatatcaat
    31141 aacataaaaa aagaatttga agaacagatc gcttatacac atcgggaaaa ggaccgttac
    31201 actttatatt tttcagaaca tatacctcga tgcaagatca tgcagcaatt gtctcaaaat
    31261 tcgttgtttt taaaaacttg tctgctttat ttggaagaag atgaacctga ttatcttcaa
    31321 ttaactgaat gtgaattcat ctctgtcagc aaagcttatt cattaaaaaa acaagtatta
    31381 gcttacttta atgactgcgg gatcgaaatc gaccgctact cccctcgatt cactgaaatg
    31441 gaaagacgtc tgctgcttct taatgtgtcg tatcgtttag gcggttttaa ttcttgggag
    31501 ctacctgaat cgttttttga acgtgccgat cgtttcattg aatccgtaac ggaaaatagt
    31561 ggcagatttt atgataaaga aaataaagaa atcttatcga ttggttttgc tatcagtttc
    31621 ctacgccagc aagtgtgtgc tgtgacaata gattcaaaat ttatcgaaga aatcaaaaaa
    31681 cgtcctattt acaattatgt cgaatcagca tgggaaaaca ctgatttcca aacctattat
    31741 aaaaaagaag aattcgcctt tattttgaca ctattcaatc tttgtaatta tggtttccat
    31801 tcttatcagt tgattgcgga agactttcaa cagctacacc aagtgtttat tgacaatact
    31861 cccgaaataa aagaactagt tgctaccttt gaatctcact tcaatcaaga attattcgga
    31921 aaccaaccgt tcgaacgtgc gctgattcat ctgatgcgtt cggcttggga taactatcaa
    31981 ttattcatgc cagaaaaatt ttatctttta aatgaggaac agacaaattt atataaagaa
    32041 gtccagacaa ttttttccag ctggtccagc cagttacctt atgatctacg gttgaatcct
    32101 aattgcatgc gggcttttgt gatcgaattg agcggaattc tccgtctgac aaaagaacat
    32161 ctgactatct atatcgtcac aaattcggat gttcattatc tgatttatcg ggaagccttg
    32221 gaagctgtaa ctactttcga ttttcaagtt gcaccaacaa tttattcaag tatatctgat
    32281 ataaagaagt atgcgcagca gtcctcaaac cgggtattat gtgaacgtac attatataca
    32341 ccagatgcgg tccaatatga aaatattatt cctatttcga tcaatacgat cgatcgagct
    32401 atcatttcag ctgtgcaaaa caaataaggg gctgtgacaa aaatcatgtc acagcctctt
    32461 atttgttgaa gatgcccatt tctgtaacaa tctcttgata cacgtcaggc tcacaacctc
    32521 acttattttg gacatctagg ggtccgatct ctttatttaa aaaataagaa atgatggttc
    32581 ggataactac caacgccgct agttggaaaa tatcctgcaa ggtaggtttg ataatcgatt
    32641 cgatgatccc agctgaaaca agaatttcca aacttagaag tatatagcct cccaacatct
    32701 ttttaatagc attgttctcg cttactcggt cgctttgcac ttttgtatgg acaaataaat
    32761 atttcaaaaa atccttgatt gatagacaaa caccccaaac caataaacag atagcaaaga
    32821 tatcaagtcc cagtacaagt ttttcgaaat atggaagaag aaactgcatc aactctgtcg
    32881 tcatcctacc tctcctcttc tttgtttttc tttgtcttct atttcctgat tcaagaaata
    32941 agaaatgact gttcgaatga taataataag tgcaagcttc aaaatatctg tccaagtcgg
    33001 cttgataact gactcgatga tatcagcaac gactagtact tccaagctta acaaaatata
    33061 acttgctagc agttttcttg tatctgcatt acgagtatta cgttctgcat agtttttctt
    33121 gacatgagac caatcaaaaa gtttgaatag aacaagaacg atcccgacaa ttaagatacc
    33181 gatagaacaa atatttaaaa tagcaatgat ccattctaga aattcaatta aatttgagcg
    33241 aaacatatac gctacctact ttcttttaat ttgttcctat tcttttattg taaaagaaag
    33301 ttaccttgtt cgtctattta aaagttgttc taatgataac ggttcgctta aatttttctt
    33361 tttcactctc ccatttttct ccctccatcc ataaatcgtg gaagtatcca aaacaacgta
    33421 gcaagttaaa ataaggctta gtccgtcatc agcttttcaa agaagcactg tctcggtgct
    33481 ttttttgtac ccaaatttct aaaaatagaa ccatacacct cctcaaatct tttcttctta
    33541 cctaccctat ttttatttac aggaaaatca gacacttctt cttttttgtc aaaatttcct
    33601 ttttcttctc gtcctatcat ttggcattct aataaaaacg aactatcctt ggatatagaa
    33661 agagaaaaca aggaggcgtt tttcatgagt aaaaaattaa tcaaagtcgg catcggttta
    33721 ggtttgcttg cccttggcgc tgcatatcta ggaaaaaaga caggactatt cgaagatgac
    33781 agtcatttat atgatgaatt cgaatcaatc tagcatccta tttagttgaa tcactacgga
    33841 catacttgga agacattgga ggaatcacaa tgagaaaaag taaagcaata atgattggtg
    33901 ccggtattgc caatatggca gcggctgttt atttgattca agaaggcaaa tggaaagggg
    33961 atcagatcac cttttattca ttggatgatc acggttcaaa tgatggtgca ccgaccgaca
    34021 ctgtagtgga tgaatattgg aataaaaacc atccattaga aaaccaaaaa ggctatattg
    34081 ctcgaggcgg tcgcatgctt aattaccgta cctatgtaga tttgatggat ctgttaagtc
    34141 gaataccttc tgttactgag ccagggatga ctgctgaaga agatacgaga gattttgatg
    34201 caaaacaccg aacctttgac aaagcacgtt tgatggaagg tggcaaagga atcattgatg
    34261 gcggaaaact gggattcaat aataaagacc gtattcttct gactaaactg attgctatgc
    34321 ctgattcaga agaagaaaaa ctagacaata tcactatcga agaatatttc aaagatgatc
    34381 cacacttttt tgaaacaaac ttctggttta tgtgggaaac aacatttgct ttcagaacac
    34441 gtagttctgc tcaagaattg cgtcgctata tgcatcaaat gatttatgaa ttcactcaaa
    34501 tcgaacatct agtgggcgtc aatcgaacac gttacaatca atacgaaagt attatgcttc
    34561 ctttgatcga gtacttgaaa gaacaaggat gcaaaatcat tttgaaccgc cgtgtcactg
    34621 actgggaatt caaagaaaca ccgatgcaag atgaaatcac tgtgactggt ttgaaaatta
    34681 ccaatacact gactcaagaa gaagaatacg ttgtggtcga tgaagataca gcagttattt
    34741 tcactaatgg gtccattaca gattcagcta ctttaggaga ttacgaaaca ccagctgtag
    34801 aaaatatgga ttatggtgca gcttctagtc tctggaaaaa agccagtgaa cgtttctaca
    34861 acttgggaaa tcctgacaaa ttctttgctg atcgagatgc aagcgaatgg gtcagcttta
    34921 ccctgacgac gaaaaaccat ttgttgttga atgaaatcac ccgtatcacg actcaagaac
    34981 caggaaatgc cttgaattca tttatttcaa ccacaccgat cacgccgtta ggccaaaaag
    35041 atgtcaatat gtctattgtc gtgcatcatc aaccgcattt tacgtctcag aaaccaaatg
    35101 aaacagttat ttggggttat ttcctttatc caagacgacg tggcgaattt gtggataaac
    35161 agtatattaa aatgaatgga aaagaaatgc tagaagaact gattggacaa ctttcaaaag
    35221 tagatcctgg accagtgaat attcgtgaaa aagaaacaga aattttcgac agcgtaataa
    35281 ataatatccc tgtctatatg ccttatgctt ccgcgttgtt caataatcgt gccaaaagcg
    35341 atcgaccaaa agtcattcct aaacattcga ccaatctggc ctttacagga gaatttgtcg
    35401 agcagcctta tcagatgatc tttactgaac aaagtgctgt acgttctgga gaaatcgctg
    35461 ctttccattt tgcgggtatt cctatgtccc gtcttgtcaa aacaccgcgt tacgacaaag
    35521 atattcctac tctagctcgt gccgcaaaaa aaatgtttga ataatcaaga ggttgtgaaa
    35581 aagctgccct gcatcaagta ataagaacaa ccaggctaaa acagcttctt atgtttttga
    35641 tttggttgga cttattaccg cagatgcaag cttttgaaca ccgtttacca agaggttatg
    35701 aaaaagctgc cctgcatcaa gtaataagag cagccaagct aaaacagctt cttatgtttt
    35761 tgacttggtt agacttatta ccgcagatgc aagcttttga acaccgttta ccaagaggtt
    35821 atgaaaaagg cgtttagttt cgagtatgaa gaaaaatttt gtgaaaatgg ttcctcacgt
    35881 ttttgcataa atttgactta ataccgagaa actgatccct tctgtcataa cctcttttta
    35941 tttatgtctg tttctttttg aaaacaacta ttttttcaac gtttactctc ttgccaatcc
    36001 aacatcatct aacggataca actatttcaa tgattaccat tacactaaaa aatcggaaac
    36061 acacctctcc gaacacaaat acataagact atagaatgtt tcatttaaga aaaaaagcgt
    36121 ttcattatca aaaaggtaag atctccttta aaatgaaatt atctgtagta ctaataatgc
    36181 agacaatttt atgaatctga aaggagcatc tccaatgaaa gcagtcactt ggcaaggaaa
    36241 acagaaaatg gaaatcagaa acgtagatga tccaaaaata ttagaaccaa cagatgcaat
    36301 catccgtatc acagcaacag ccatttgcgg ctccgatctg catctttacc atcatggtga
    36361 agcagttttg gaaaaagggt atgttgtagg acacgaacca atgggaatcg ttgaagaagt
    36421 gggatctcaa gttcaaacat tgaaaaaagg gcaacgtgtg gttatccctt ttaatattag
    36481 ttgtggtcat tgtcatttct gcctgaatca catggaaagc caatgtgatg aatcaaatcc
    36541 agatcagtta tatggcgggc ttttcggatt tggcaagttg aacggtaatc attggggtgg
    36601 tcaagcggaa tatctaagag ttccttatgc agactctact tcatttgttg taccagataa
    36661 tgatcttcct gatgaaaaag ttttatttct atcagatatt ttgcccacag cttattggag
    36721 cgttgaaaac gcaggagtaa aaaaaggcga tacagttgtg attctaggtt ctggtccagt
    36781 cggtctattc gctcaaaaat tcgctgttat ggctggagca gagcgcgtaa tcgcagtaga
    36841 tccagtacag caccgtctag ataaagcggc taattacaat ggggttgaaa cttatttctt
    36901 agaagacacg gcacaagctg gaacagaatt gtatgaactg gctaaaggtg gcgcagatgt
    36961 cattatcgat tgtgtaggaa tggacggatt agagcctgtc aaagaaaaag cgaaaaattt
    37021 agtaagctta caaagcggca caatctctcc attacagatg gcatcgcaag ctgtcaaaaa
    37081 atttggaaca gtccaagtaa ctggtgttta tatgactcca gcttcttctt acccgctgca
    37141 agaatttttt atgcgggata tcgctgtcaa gcatggacag gcaccaatta tccatctaat
    37201 gccaaaaatt tacgcaatga ttgcagaagg actattcgat cctacacaaa tcattactca
    37261 ttcgctgcca ctatcagaag cagcacaagc atatgagatc tttgacaaaa aagaagataa
    37321 aaatataaaa gttgttttga aaccttgaat tcagtaaaaa atacaggtga ttttctttat
    37381 gcccaaaatc aaacgaaata cccatgagat cgaaatagga aaagaagaag atatcgaaat
    37441 acgaggacgt cgcttccgct tctatttcca aaatcgttac acattgatct cactggctgt
    37501 cgatttatta accgggattt tctatatttt tggaagcctt gcttccttaa ctaaaatccc
    37561 cgatcgatat ggcacctatt tttatttggc tggtgctatt ttcttgacga ttcgtcctat
    37621 tctcagaatc gtaaggaaca tttttattta cgacgaaaaa aaagcaatga agagaacaag
    37681 caaaaaaaaa gaggcatgag aatttttcaa atctcatgcc tcttttttca ccctatcgta
    37741 tcactttgat acagacgagc ggtcgtccca ctttcttcct tgaccattgt caaaaatgtc
    37801 cactcgtatc gttcataaaa cgtggtatga tctgtaatta agtaaagttt ttcgtaccca
    37861 agttgatgca tttcttttct gatttccgct aatatccgct tggctatccc ctgcttacgc
    37921 ttttccggtt caacaaacag ggcacaaaga tttggtgtca gatcagggcg gttatggaag
    37981 tcgttttcaa tgacgcccgc tcctccgacg atggtttctt tttcatctaa gaccacatac
    38041 cattgaggaa tactttcctt attagcgatt ccagtacgaa tactttcctc atacacaaca
    38101 gcaggaactc cccattttga tgaaaaccaa ttcgcgcttt gttttactaa ttctgggtgt
    38161 tctcttaatt tgatccagtt atatgtaacc aatgtttaaa cctccgacta aaataaaacg
    38221 tttacaaaaa ttatacaagt ctttatgaaa attagcaatg acaacaatag tgatgtaaaa
    38281 aaaaaaacgg aaaacaatca cttgttctcc gttttttgat taatcaagca tctaaagctt
    38341 cttttcttct ttcttggatc gtagctacct tgacgaacgg tagatagatc aaaatagaaa
    38401 gaaccaaatt gacagcggct agtacaccac ctgcaatact ttttgttgcc aatacaccgc
    38461 caataattgg tggagttacc catggaggca taacggtagc tgctggcact aaacctgtag
    38521 aagtcgcaaa gtaagcaaca ctaactaaga ccattggtgt caaaataaat ggaatgaaca
    38581 tgatcgggtt caacacgata ggtaacccaa acatcgttgg ttcattaata ttgaagacac
    38641 ctggcgcaat cgacaagttt gttacaacca tatatggttt gtttttacgt cctactaaat
    38701 aaatagctaa cagtaaacct aaagttgcac ctgttcctcc taagttgaca aagctgtcaa
    38761 agaaaggttt gttcacgata aacggtgcgc tatgtccagc tgcgattgca ttaacgtttg
    38821 cttcaatggc tggcgcattg attgtttgca tcaaaggatc gaccatattc gctccgtgta
    38881 aaccaaagaa ccataagaat ggtgtgataa atgcaagcag taaggcagat ggataagagt
    38941 ttgcaagtcc cataaatggt tcttggacca ctgtatagaa agaacctacg atatcatcaa
    39001 caccgaatgc agcaaaaatt gcagcaacta aagcaaacgc agagatagtg atcattgctg
    39061 gtagtaatga agcaaatgct tttgcaactg ccggtggcac accatcaggc attttgatga
    39121 tcaatttttc atttccgctt aaacgtacaa agatttctgt tgaaataatc ccaacaataa
    39181 tagcaataaa caaaccgttt gagctcatac ctaatgctcc gcctaaagcg aagaaagagc
    39241 ctaaagaaat cacacctgcg gaaacaccgt cttttcggta gccgttagct aaatgataag
    39301 caagcaagaa agcaatcaag acagaaagaa tggcaaatgt accgttccaa gcagcagccc
    39361 cgaatccttt ccatgattca ccaccaaaaa ttgagttcat caattcttgg aacccgggaa
    39421 tcggtaagtt attgatcatt actgctaatg ctcctaagat cattaacggc atactcacca
    39481 taaatgagtc ccgaatcgca actaaatgcc gttgtgcacc aatttttgat gctacaggta
    39541 taaaatgttt ctccataaat gcaacaaatt tatccataaa tcttccctct tttctttact
    39601 gtagattacg cgttcaatcg acgatacaga ttaatgatct cttttgctaa atctgtaaaa
    39661 gctatagatg tcatcagatg atcttgactg tggaccgtca aaagcgtgac ttcaacgtga
    39721 tttccttgtg cttcttgtgt cagcatctct gtttgagagt gatgtgcttg gactaaagat
    39781 tcctctgcat ctttgatttt ttcatctgct aaagtgaaat cacctttttt cgcagcagca
    39841 atcgcttcca ttgcatcgct ttttgcattt ccgccaaaca tgatcagacc catgatggct
    39901 tctagatttt tttgatcttc catttattgt atcctccgat aatttttatt atttgtttat
    39961 tagtttttct gcttggtcga gtactttttc accattcatc atgccatagt cagccatatt
    40021 gattacatct aaaggaatgc ctttaggtgc tagcttttca gcaaattgat tttgcataaa
    40081 gcgtacttgc ggtcctaaaa gtaaaacgtc tacattttta gattctagtt gattatccgc
    40141 atctgaagca gatacagcaa agatgtctgc ttccattcct tttgcttctg ctgccttttg
    40201 catttttgtg actaggagac ttgtactcat tccagctgaa catacaagca tgattgtttt
    40261 cttttccatt ttaaacacgt tcctttctat acttacactt gtatataagc aagtagcgtg
    40321 ccaactttaa aagcgcttta aaaagttgat atcatcacat ttaaggtcta taccaagttg
    40381 catacacact aaaaaagaaa gcgcacacta aacacacaaa ttaattttta ttaccttttt
    40441 tcttttaacg tgcacaaaaa aagttgtgac acaaaacttg tcacaacttt tttcaaataa
    40501 acggtattca aaagcttgca tctgcggtaa taagtccaac caagttaaaa acataagatg
    40561 ttgtttttac tttgctattc ttattacttg atgcaggaca gctttttcac aacctctcaa
    40621 taaacggtgt tcaatcagct gaccctgggt attagctcaa aacgctggat tcacaacctc
    40681 ttttatttca aataaccagt aaatacaatg aacatctaca aaaaacttct atttatttat
    40741 agatttcgtc aggcaaatcc aattctctct tatcaatcaa agtctgatac cacgaagcag
    40801 attttttcaa tgttctgctt cgttcatcgt tcaattcgat tcgaactaat ccatatcgat
    40861 tcttaaatgc attcattggt gacacacagt cagtgaatgc ccataacata tagccttcgc
    40921 aatttgcgcc ttcttctgtt gctttgatca agtaatgcaa atgctgtccg ataaattcga
    40981 tacggtaatc atcttgcacg attcctttct catccatata ctgttcttca tattctcttc
    41041 ccataccgtt ttctgttatc agccaaggga tattatgata attttctttt agatacatgg
    41101 ctatatcata catgattttc ggatagattt cccatcccct ggaattattc attttcttcc
    41161 caggtaaatc aaagacttca taatatcgtt caggatggaa aggtgtctct tcattccatt
    41221 gataacgagg ggcgcgaacg cgtttaggat aatattgatt gattccaagg aaatctactg
    41281 tatgatgctg aatcgtttct aaatcctctg ttgcaggatc gaaataaatc gattgttttt
    41341 gacacaactc caggaactct tctgtgtagt atccttttac catcggatca aaaaatactc
    41401 gattataaaa caaatcatac atataagcag ctttttggtc ttctggagaa ttggatcgag
    41461 catagaccat ttcaggattt aaaatacagc caatccttcc accataattt ccgctgcggt
    41521 aaatctctac tgctttagcc gttgctaaaa ctttatgata attccacatc atccactttt
    41581 ttgtgttttg ttcatgcggc cagcgaacag catccaaata gcaacgcgtt tggggaacga
    41641 ttggttcgtt gaatgtaaac cagtttttta ccctatcacc gtaacgatca aaggcaattt
    41701 gagcatactt agcataaaaa tcaactactt ttcttgaaga ccagccatca tatttttcca
    41761 aaagaaaagc tgggacttca taatgttcca aacaaatcat cggttctacg tctgcttcga
    41821 tcaaagagtc gatcatttca cttatatgct gagcatattc ttcatctact atacagttct
    41881 cataatcagt aaaaaaacga gcccaattga tagaagtccg ataatgtgtc agatggatgg
    41941 atttcatcag atccacatcc tgctggtatt gttccataaa attagttgct acggctgggc
    42001 catacccatt atgccaaaca aaatgttcat ttttatacca gctatctata aacgaatcct
    42061 gtccttcttt ttttcctttc caaccttccg tttgccaagc agaagatgca gcaccaagaa
    42121 taaaattttt tggaatagta attttcatga tttcctcctg ttttttagat cccatcattt
    42181 tccacacgat ttgctacttt tacaaatggc agatagatca aaatagaaac aataatacaa
    42241 acaagttgcg taataactgc accgatattt cctgctgttg ccagataagc attgacgatc
    42301 ggcggcattg gccaagggac cattacaact gctttcgccg caaatcctaa agcggttgca
    42361 aaataaccaa tcgttccagt gataagaggc gttaagataa acggaatagc taaaattgga
    42421 ttcagcatga tcggcatacc aaaaataact ggttcattga tgttgaagat cccaggagca
    42481 agggataact tggtgatttg tttcatatct tcccgttttc caactaacaa tactgcaatc
    42541 agtaaaccga tcgtgactcc agacccgccc atactcatat acatatccca aaatggcata
    42601 gtaataatgt tcggtacttc ttttccagct tcaaaagctt ccgtatttac agcaattgcc
    42661 gctaaaagca acggttcccg tatcggcttc accatttgat ttccatggat accaatcacc
    42721 caaaagactt gcgcaataaa catcaatagc aaaatacccg gtaacccttg tacgacacct
    42781 tctaatgggc gttgtacgac attgtaaatg atatcataaa ggtacattcc tgtaagttct
    42841 ttgatgataa atcccgcagc cgcgataccc gatacagtca gaatcgtcgg gaataaagca
    42901 gaaaaactag cagaaacatt cgttggcacg gtatcaggca ttctcagctg tagtttcttc
    42961 tgtttcctca accagcaata aagttcaata gaaaggatgg agaccaacat tcccaaaaat
    43021 aaccctttcg tatctgtata ttgtttagcc aatacgtttt ctactataac agtctgattt
    43081 tcattcacta attcataaac agttggatta acagataaat aagacatcac tgcgatgata
    43141 ccagggaata caccatccac tttattcagc ttggctaatt cgatccctat cagaaaaaca
    43201 gcatagatgg tcaagaaact tagtgtgaca tagctgatgg cagatgcgat aggctttaat
    43261 tcttctaaaa aacgcaagaa acttatctgt gctaagccat tttccgagtc aaagaccatt
    43321 gctgaaaaca atgtgccaaa agcacccgta ataattaccg gaatcaatgc agcaaatgcg
    43381 ttttttatca ccatgatata ccttaaatta ttgattctcg ttgccacgtt ccctaaaaca
    43441 ttggctaatt tatccataaa actcattcca gatcccctca ttcctgcttc ttctccttga
    43501 cgtcatctct ttttgtctat tagtcagcgc ttacatttcg atgaacagaa actatttact
    43561 cctctttttt accaaatata aaacaaaaat tcatctgatg tatttatcat aaaatacatc
    43621 agatgaactg tcaattagtt tctttttctc ctattatttt ctgtaattct ctccgattta
    43681 ttgccatatg gacagtcatt gcatcaaacg cagcaagtgc attccgcctt tcgatggcct
    43741 gaacgatctc tgtatgaata tcgatcgtct cgattttcag atgctggata tcataatttt
    43801 tattaaacaa agcaattgat tcattaatga ttgggataat atgcagcaag gctacgtttc
    43861 cgctagcttc tgcaatcatc gtatgaaaat cgatgtctaa ttgaacatgt tcttgtgtgc
    43921 cttctcgaaa agaagtttca atcttttgcg ttaatttttt catttggacg atttgattct
    43981 tcgttgcata ttccgctgcc aaacctgcca tcttaggctc caataaatat ctcagttcaa
    44041 ataagtctcg tatcatccga tcctgatctt caatcaaaga aaaaccgagt gggtcattgg
    44101 caatccctcg cttatcactg acaaatgtcc ccgctccttg ccgaacttca aggatattcc
    44161 tggaagctag agcccgcaca gcttctcgca ccgtgcttcg ccccacctct aaataatcgg
    44221 acaattcata ttcattcggc agtttatctc ctacttgcaa ctgcatttcc tttaaatatc
    44281 taaggatctt gtcagtagtt acttctacta gggttttatt ttcttccaaa ccacatacct
    44341 ccttttcatc tgatgtattt tttcgtaatt attataacac gtttgaatca tctgatgatt
    44401 ttttgtatac aaaattgatt aatccgttca tagacataca aacgaagaag atatttacca
    44461 taaaaaagac taggataaaa ttcactccta gccttcgatc atttttattt tgaacgacaa
    44521 aaaatatgat gttcaataac agacgatctt cattcgattc ttgatgtcat cttttgtttt
    44581 ttttaatata tggataaaaa gtttgattac atcgtttcta ttctagaatt tggtcgattc
    44641 tcaattcttc ttctggtgag aaatctaaat tatccatcat tcgaacactt tcttgtaact
    44701 gacttaaccg acttgctccg accagtacac ttgtaacaga tttttgtcgc aaattccatg
    44761 caagggccat ttgcgctaat gattgtcctc gtgatacggc gattgtttgc agtgctttga
    44821 ttttttccag agttgatcca acttgttctt ctgaaaggaa tggtatttcc ttacgatgtg
    44881 ctctagaatc ttcaggaata ccatgtagat aacgatttgt cagcaaccct tgagcaagcg
    44941 gactgaacgt gattgcccct agcccttctt cttctaatac tggagataga tcgtcttcta
    45001 gtagtgcacg agaaaacata ttgtagcgca tctgatgaat aatgaacggt gcttcctttc
    45061 tttttaaaat ttcagtcatt ttttttgtat cttctccatt atagttggat ataccaatat
    45121 ataatgcttt tccttgtctt acaagttgca tcaaagcttc tgctgtttct tccaaaggtg
    45181 tatcagggtc tgggcgatga tgatagaaga tgtcaacata atctagcccc attctttgga
    45241 gactttggtc acaacttgaa atgatggatt tacgagagcc ccattcccca tatggccctt
    45301 cccacatatg ataacctgct ttgctagaaa taatcagttc atcacggtag gcttgaaaat
    45361 cttctctaaa aatacgccca aagtttttct ctgcagctcc agcagggcct ccataattat
    45421 tcgcaaggtc gaaatgggta attcccatgt cgaatgcgcc tcttaaaatc tctctttgat
    45481 tatggatagg atcataatca ccaaaatttt gccataatcc gagagataaa atcggtaatt
    45541 tcaaacctga atgaccggat ttacgatatt ccattttttc ataacgtgca ctatctgcaa
    45601 tatacaattt ttctcctcct catcaaatct ttttaaaacg ctttcttttt tctattttta
    45661 gtttactaca ttttaaagaa aaggagttaa tcaaaatgat tttttcgtat atttttttgc
    45721 catttgtttt ttactcgttg atagatcaga aattgattac gtgcttgctg gattttttta
    45781 taacgtttcg gttgtttttt gtaaaattgc tgatgatagt tttctgctgg ccaaaacgta
    45841 ccggctggtt cgatttttgt gacgattggt tggtggaaag ttcctgaact gtctagtttc
    45901 tgttttgatt gttccgctaa ttctttttgt cgttcgactt gataaaaaat cactggacga
    45961 tattgcttcc ctctatcttg aaattgtcca aatgtatctg tgggatcagt aatttgccaa
    46021 tagattgtca gcaactcgct ataacttatt tctcttgtgt cataaatgat ctccacagct
    46081 tccacatgac ctgtgtaacc accacttact tgatcataat ttggtttttc aacatgtccg
    46141 cccgtgtatc ctgacaaaac agataggatc ccttttttcg attcaaacgg ctcgaccata
    46201 caccagaaac atccccctgc aaatactgca cgttcttgat agtcagcatc ttgcatggca
    46261 tgcttggaaa agtcatattt ttgctcctta tcaaatcctt ccgtaatcaa taaataaaag
    46321 tccattacat caggcgtcag attcattcgg atagctaatg gacgtagtgt tgcttctagt
    46381 tttgataact gttctttaac ggatatattt tctcttatgt cattctttgt ctgaatcaat
    46441 acttttcgtt cccaatctcg tgtattcgga ttcaaaatca gattataaag tgtttgaatg
    46501 aatatttgtt cctcatccat agattctcct cctttccgaa gaagacaagc tagtgacttt
    46561 agctgtaatt tatcataaag tgaggaaata agcgattact tcatccccct acagattttt
    46621 cgtataaaaa agagagaatc cttatcgaca gattctcctt tttaatcaat ttattttata
    46681 aatgaaaagt taatttacct tttatggaaa actattttaa aaaataaaca taaatat
//
LOCUS       DAFTHM010000011        42377 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFTHM010000011 DAFTHM010000000
VERSION     DAFTHM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.011"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            818..2428
                     /locus_tag="L7C88_000645"
     CDS             818..2428
                     /locus_tag="L7C88_000645"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBP9557500.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            2720..3589
                     /locus_tag="L7C88_000646"
     CDS             2720..3589
                     /locus_tag="L7C88_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBP9557501.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            3754..5025
                     /locus_tag="L7C88_000647"
     CDS             3754..5025
                     /locus_tag="L7C88_000647"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBP9557502.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            5022..6317
                     /gene="rho"
                     /locus_tag="L7C88_000648"
     CDS             5022..6317
                     /gene="rho"
                     /locus_tag="L7C88_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBP9557503.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            6416..6679
                     /locus_tag="L7C88_000649"
     CDS             6416..6679
                     /locus_tag="L7C88_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBP9557504.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            7124..7573
                     /locus_tag="L7C88_000650"
     CDS             7124..7573
                     /locus_tag="L7C88_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBP9557505.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            7630..9048
                     /locus_tag="L7C88_000651"
     CDS             7630..9048
                     /locus_tag="L7C88_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBP9557506.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            9048..9908
                     /locus_tag="L7C88_000652"
     CDS             9048..9908
                     /locus_tag="L7C88_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBP9557507.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            10082..10855
                     /locus_tag="L7C88_000653"
     CDS             10082..10855
                     /locus_tag="L7C88_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBP9557508.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            11002..11367
                     /locus_tag="L7C88_000654"
     CDS             11002..11367
                     /locus_tag="L7C88_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBP9557509.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(11515..12723)
                     /locus_tag="L7C88_000655"
     CDS             complement(11515..12723)
                     /locus_tag="L7C88_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9557510.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(12742..13020)
                     /locus_tag="L7C88_000656"
     CDS             complement(12742..13020)
                     /locus_tag="L7C88_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557511.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            13174..13869
                     /locus_tag="L7C88_000657"
     CDS             13174..13869
                     /locus_tag="L7C88_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBP9557512.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(14311..15108)
                     /locus_tag="L7C88_000658"
     CDS             complement(14311..15108)
                     /locus_tag="L7C88_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBP9557513.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(15105..16289)
                     /locus_tag="L7C88_000659"
     CDS             complement(15105..16289)
                     /locus_tag="L7C88_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBP9557514.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(16314..17561)
                     /locus_tag="L7C88_000660"
     CDS             complement(16314..17561)
                     /locus_tag="L7C88_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBP9557515.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            17776..19521
                     /gene="dnaX"
                     /locus_tag="L7C88_000661"
     CDS             17776..19521
                     /gene="dnaX"
                     /locus_tag="L7C88_000661"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBP9557516.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            19541..19855
                     /locus_tag="L7C88_000662"
     CDS             19541..19855
                     /locus_tag="L7C88_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBP9557517.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            19880..20476
                     /gene="recR"
                     /locus_tag="L7C88_000663"
     CDS             19880..20476
                     /gene="recR"
                     /locus_tag="L7C88_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBP9557518.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            20540..21184
                     /locus_tag="L7C88_000664"
     CDS             20540..21184
                     /locus_tag="L7C88_000664"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBP9557519.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            21199..21528
                     /locus_tag="L7C88_000665"
     CDS             21199..21528
                     /locus_tag="L7C88_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBP9557520.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            21542..22480
                     /gene="holB"
                     /locus_tag="L7C88_000666"
     CDS             21542..22480
                     /gene="holB"
                     /locus_tag="L7C88_000666"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBP9557521.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            22516..23340
                     /locus_tag="L7C88_000667"
     CDS             22516..23340
                     /locus_tag="L7C88_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBP9557522.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            23333..23680
                     /locus_tag="L7C88_000668"
     CDS             23333..23680
                     /locus_tag="L7C88_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBP9557523.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            23749..24621
                     /gene="rsmI"
                     /locus_tag="L7C88_000669"
     CDS             23749..24621
                     /gene="rsmI"
                     /locus_tag="L7C88_000669"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBP9557524.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            24730..25851
                     /gene="dinB"
                     /locus_tag="L7C88_000670"
     CDS             24730..25851
                     /gene="dinB"
                     /locus_tag="L7C88_000670"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBP9557525.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(25905..26507)
                     /gene="nrdG"
                     /locus_tag="L7C88_000671"
     CDS             complement(25905..26507)
                     /gene="nrdG"
                     /locus_tag="L7C88_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBP9557526.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYAFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(26822..29011)
                     /gene="nrdD"
                     /locus_tag="L7C88_000672"
     CDS             complement(26822..29011)
                     /gene="nrdD"
                     /locus_tag="L7C88_000672"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBP9557527.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGSFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            29310..30104
                     /locus_tag="L7C88_000673"
     CDS             29310..30104
                     /locus_tag="L7C88_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557528.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            30094..32136
                     /locus_tag="L7C88_000674"
     CDS             30094..32136
                     /locus_tag="L7C88_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557529.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            32417..32566
                     /locus_tag="L7C88_000675"
     CDS             32417..32566
                     /locus_tag="L7C88_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBP9557530.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            32577..34091
                     /gene="dltA"
                     /locus_tag="L7C88_000676"
     CDS             32577..34091
                     /gene="dltA"
                     /locus_tag="L7C88_000676"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBP9557531.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            34088..35293
                     /gene="dltB"
                     /locus_tag="L7C88_000677"
     CDS             34088..35293
                     /gene="dltB"
                     /locus_tag="L7C88_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBP9557532.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            35338..35571
                     /gene="dltC"
                     /locus_tag="L7C88_000678"
     CDS             35338..35571
                     /gene="dltC"
                     /locus_tag="L7C88_000678"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBP9557533.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            35574..36842
                     /gene="dltD"
                     /locus_tag="L7C88_000679"
     CDS             35574..36842
                     /gene="dltD"
                     /locus_tag="L7C88_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBP9557534.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            36983..38065
                     /locus_tag="L7C88_000680"
     CDS             36983..38065
                     /locus_tag="L7C88_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBP9557535.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            38065..38868
                     /locus_tag="L7C88_000681"
     CDS             38065..38868
                     /locus_tag="L7C88_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBP9557536.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            38938..39678
                     /locus_tag="L7C88_000682"
     CDS             38938..39678
                     /locus_tag="L7C88_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBP9557537.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            39689..40693
                     /locus_tag="L7C88_000683"
     CDS             39689..40693
                     /locus_tag="L7C88_000683"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBP9557538.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(40738..>42377)
                     /locus_tag="L7C88_000684"
     CDS             complement(40738..>42377)
                     /locus_tag="L7C88_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557539.1"
                     /translation="DSKYTRTIPTVDKDETFIMETTLEKPLDEANLLIKGNHQWITVY
                     LGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNYAGLPPKVYLGT
                     TGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLILLSCFALALG
                     FEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKKWYGIFCTFQLL
                     IFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNRFYVACTPWIVL
                     VAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNTDKDRRQVDFLK
                     IKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKNYVEKILEEAKN
                     FEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDDLAQLLIHALEH
                     SFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGITEELDDQERFDL
                     MMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        13602 a         7417 c         8810 g        12548 t
ORIGIN      
        1 accgtttatc cagaggttgt gagcctacca tttaactccg aatcacaaga aataatttca
       61 aaaacagctt ctcatgtttg atggatattg tgacttgtga ccgaggagtt ggcaggagaa
      121 caccgtttat ttagaaataa ggaggcacga cttttgtcgc atctccttat tttttactta
      181 tgtgattcgt taccttcaat gaatccctac aaggcacttt tgttgaaaaa aaggtcatct
      241 ttgaaaaaat tagtggaatt gttttgtttt tgatattatt taatagaaaa gatatgccaa
      301 aaatccgaga actgtggact acgtttttta cgtaaaggag gtaaataagg gtgaaagaaa
      361 aagattgttt ctacgataag ctatataaac tgttgctgca agtaggaaaa agtagttctt
      421 tgttaggtgg gatattatct atcataatgt ttgttttatt tttttatcta ttatttcact
      481 taaaattttt cagtaacgat tttctgattt gcttaggttt aacgttagct atgtttatat
      541 caagcttatt atgtgggtta aatttttttt gcactcataa aggacttaag aaataatttc
      601 tcaaaggata tcgaaaaaga aaaaattgta agcggatagt attcatttga gtacttgact
      661 ttcccttagt cagcttgtat tatacacctt gggcaccctt ttagagggtc agaagtttac
      721 agaaatttcg gctccctatt cttattgaag aatagggagc tttgtttatt gtctgagact
      781 tttcctgcac ataaattaaa aaggagtttt tgaacttatg acaaaatata tttttgtgac
      841 cggcggtgtc gtttcatcaa tcggaaaagg gattgttgca gcttctttag gacgcttatt
      901 gaaaaaccgc ggcttaaaag taactatcca aaaatttgat ccatacatca acgtggatcc
      961 ggggacgatg agcccatatc agcacggaga agtattcgta acagatgatg gtgctgaaac
     1021 agatttggat ctgggccact acgaacgttt tattgacatc aatttgaaca aatactccaa
     1081 cgtgacgaca ggaaaaatct attctgaagt tttgcgtaaa gaacgtaagg gcgaatactt
     1141 gggagcaact gttcaagtta ttcctcatat tacaaatgag atcaaagaaa aaatcatgcg
     1201 agcagctaaa atgactgatt cagatgtgat cattacagaa gtagggggaa cagtagggga
     1261 tatagaatct ttgccattcc ttgaagcact tcgtcaaatg aaagcagatg tcggtacaga
     1321 taatgttatg tatatccata caacattgat tccttacttg aaagctgctg gagaaatgaa
     1381 aactaaacca acgcagcaca gtgtaaaaga gctacgtggt ttaggtatcc aaccgaatat
     1441 tttggtggta cgtacagagc aacctgtttc tcaaagcgtg aaaaacaaat tggcacaatt
     1501 ttgtgatgtc gaaccagaag cagttatcga gtcgccagat gtagatacac tttactccat
     1561 cccattagtt ttacaagcac aaggaatgga tcaaattgtt tgcgaccatt taaaactaga
     1621 tacaccagaa gcagacatga cagaatggaa agaattagaa gaacgtgtct tgaacttgaa
     1681 gaaaaaagta cggattgcgc ttgtcggtaa atatgtcgag ttaccagatg catatatctc
     1741 agtagttgaa gcattgaaac attctggttt cgcctataat tcagacatcg agatcgattg
     1801 gatcaaagca caagaattaa cgagagaaaa tgtagaagaa cgtttgaaag acgcagatgg
     1861 aatcttggtt cctggtggat ttggtgatcg cggagtagaa gggaaaatcg aagcgattcg
     1921 ttatgctcgc gaaaatgacg ttccgttttt aggtatttgt cttggtatgc agatggcttg
     1981 tgtcgaattt gcacgtaacg tcgttggatt agaagatgcg tcatcagctg aaacgaatcc
     2041 agatacagca aacaatatta ttgatttaat ggctgatcag gaaaacatcg agaatttggg
     2101 tggaacttta cgccttggat tatacccatg taaaatcaaa aaaggaacga agacggctga
     2161 agcatatgat ggagccgatg ttgtgcaaga acgtcaccgt caccgctatg agttcaataa
     2221 caaatatcgt caattgtttg aagaacaagg gctagtcttt tcaggtgtct caccagataa
     2281 ccgtttagta gaaatcgtag agctgccaga gaaaaaattc tttgtgggat gccaattcca
     2341 cccagaattg atttctcgtc caaatcgccc gcaaaaatta atcaaagcat ttgtcggagc
     2401 atcattagca gatcacgaaa caaaataatt tttgaacttg atagaaagag aaaagtagca
     2461 agagaagggg ataagcaatt ttcttgtcac ttttctcttt ttctgatttg ttattatttg
     2521 taggaaaaaa gatagaaagc aaaagacttt tttcgattaa agcgctattg gatattttat
     2581 tttttgcaaa aaacttcttg aaaattttca ttttcattga ttttagtaga aaactaccga
     2641 aatgtttggt aaaatagggt cgttggttaa gaattgtctt aacaaattta gttttacaaa
     2701 acttaggagg aattttatta tgccagtagt atcaggagct gaatttttaa aagctgctcg
     2761 taaaggcggt tacgctgtcg gcggattcaa cacaaacaac ttggaatgga ctcaagcaat
     2821 ccttgaagcg gctgaagcaa aacaagcacc agtacttatc caaacatcaa tgggtgcagc
     2881 taaatacatg ggtggttaca aaatctgtaa agatttaatc actgatttag ttgaagcaat
     2941 gaacatcact gttccagttg ctatccactt agaccatggt gattacgaag ctgctttgga
     3001 atgtatcgaa ttaggctata cttcagtaat gttcgatggt tcacatctac catttgaaga
     3061 aaacttgaaa ttagctaaag acgttgttga aaaagcacat gcaaaaggta tctcagttga
     3121 atgtgaagtt ggttcaatcg gcggagaaga agacggaatc atcggtaacg gcgaattagc
     3181 tgatattgaa gaatgcaaac aaatggttgc tacaggtatc gactacttag cttgcggtat
     3241 cggtaacatc catggtcaat atccagaaaa ctggaaagga ttagcttttg accacttaca
     3301 agcaattgct gatgctgtag gtccagacat gcctttagta ttacatggcg gatcaggtat
     3361 tcctcaagat caaatcgaaa aagctatctc aatgggtatc tcaaaagtaa atgttaacac
     3421 tgaattccaa ttatcatttg ctgcagctac tcgtaaatat atcgaagctg gtaaagataa
     3481 agaaggtaaa ggattcgacc ctcgtaaatt attagctcca ggtaaagcag caatcgttga
     3541 agatgctaaa tctcatatcg actggttcgg ttcagctaac aaagcgtaag catccacata
     3601 acagatacga tatataggaa tggagaacga cttttgaagt cgctctccat tcttttttac
     3661 ttaaaacggc agaccatgct cgtttctttt ttttatctat gataaaatac aagcatatcc
     3721 atgaaaaaag attaataaac aaggtggaaa cagatgaaaa aaatcgtaat caaaggaaac
     3781 cgacctttag ctggtgaagt aacgatcagc ggtgcaaaaa atagtgcagt cgcattgatt
     3841 ccagctgcaa tcttagctga ttccccagtg atcttggaag gtgtgccgga catacaagat
     3901 gttcattcat taattgaaat tttagagatc atgggcgcaa ctgtccattt ttccaacaac
     3961 atactagaaa tcgatcctcg agaagtcgta tcgattccga tgccgcacgg aaaaatcaat
     4021 agtttgcgtg cttcttatta ttttatggga acactgcttg gtaaatttgg cgaagcggta
     4081 gtaggcctgc caggtggctg ttatttaggc cctagaccga ttgacctaca cgtcaaagga
     4141 tttgaagctc taggtgctga agtgacaaat gaacatggtg ccatgtattt acggacagaa
     4201 aataaaggat tgcgtggcaa tcggattttc atggacgtgg tttcagtcgg agcaacgatc
     4261 aatgtgatgt tagctgctgt aaaagcaaaa ggacagacag taattgaaaa cgctgcacga
     4321 gaaccggaaa tcatagatgt ggcaacttta ctgaataata tgggggcaaa agttcgagga
     4381 gcgggtacag atgtgatccg tatcgaagga gtcgaaacat tacatggctg tcggcatttc
     4441 atgattcctg accgcatcga agcaggaacc tatctagcat tagcagctgc agtaggaaat
     4501 ggtatcaaag tgaaaaatgt gatctttgaa catttggaaa gctttatagc aaaattgcag
     4561 gaaattggtg tccatatgaa aatcagcgaa gatgaaatcg aagtttaccc ctcgaaagaa
     4621 ttaaaacccg caaacatcat gacctatcct tatccaggat ttgccacaga tctgcagcag
     4681 ccacttactg cgttactatt gatgactaca ggcacttcag aaatcatcga tacgatctat
     4741 gcgaaacgtg tgaaccatgt gccggaacta gcacgaatgg gcgctgatat taccgtggaa
     4801 ggaaatatga tcatcgtgaa tggtccaaat aaacttcacg gcacagaagt cgtggcttct
     4861 gatcttcggg caggtgcttg tttagtgatt gctggactat tggcagaagg gacaacgacg
     4921 atttacaatg tagattatat cttacgcggt tatgatcata ttatcgagaa actaacagcc
     4981 ttaggggcat caattgaaat gatagaggaa gtgggagctg aatgagcgat tatttgacaa
     5041 tggcagaact agagaacaaa acgttaaaag aagtttatag ttatgccaaa gaatttaaaa
     5101 ttccttatta cagtaagatg aataaaaagg aattatctct agctgtgatt cgtgcacaag
     5161 cagagaaaca aggattttat tatatggaag gaatattgga tatcgttggt caagatggtt
     5221 acggtttttt acggccaatc aattatggac caagtgcaga agatatctat atttctgcct
     5281 cacaaatcag acgattcagt ttgagaaatg gggacaaagt ggcaggaaaa gcccgtccac
     5341 ctaaagaatc ggaacgttat tatggtttga tgcacgtgga aagcgttaat ggaaaagatc
     5401 cggaagaagc aaaagaacgt ccgcattttc cagccttaac acctctttat ccgcaaagac
     5461 agcttcaact ggaaacaaca ccgcaaagac tatctacccg aatgatcgat atcttttctc
     5521 caatcggttt tggtcagcgt ggattgatcg tcgcaccgcc aaaagcaggg aaaacttctg
     5581 tattaaaaga aatcgcaaat ggtatcaccg aaaactatcc ggaagtagaa ttaatcgttc
     5641 tactgattga tgaacgaccg gaagaagtaa cggatctaga acgaagcgtg aaaggcgacg
     5701 tggtatcttc tacatttgat ctgcagccgc aaaaccatac tcgagtttct gaattagtat
     5761 tggaacgcgc aatgcgttta gtcgaagata aacgagatgt cgttatcttg atggatagta
     5821 ttactagact tgctcgggcc tataacttag tcgttccacc aagcggacgt acattgagtg
     5881 gcgggattga cccagccgca ttgtataaac ctaagaaatt tttcggggca gcaagaaaca
     5941 tcgaagaagg tggcagtttg acgattttag cgaccgcttt agtcgataca ggaagccgta
     6001 tggatgacgt gatctatgaa gaattcaaag gaactggaaa tctagaatta caactttcac
     6061 gtgaattatc tgaacgtcgg atcttcccag ccatcgatat caaaaaatca ggtacccgaa
     6121 aagaagaatt attgatgcca agtgaagaat tagaagaaat ttggaaactt cgaaaaaata
     6181 tgactggaga ttcattagaa tatacggaac aactgatccg ctttttgcgt aaaacaaaaa
     6241 acaatcagca atttttcaaa gaatttcaag atgtctcctt tggtaaaaaa aatccgacca
     6301 gaaatctgaa aagataattg caaccttgac tgaaacatgt taagatgtta atgttgtaaa
     6361 tcgacaaatc aactctggtt cagcaaatgg agcagggcaa aggagcgaaa aaatcatgaa
     6421 agaaaacatc catccagatt accacccagt agtattcatg gattcaacaa ctggtttcaa
     6481 attcttgtca ggttcaacaa aaacttcaca agaaacagtt gaatgggaag acggtaatac
     6541 atacccagtc atccgtgtcg aagtaacttc tgactcacat ccattctaca ctggacgtca
     6601 aaaattcaca caagcagacg gacgtgtgga ccgtttcaac aaaaaatacg gtctcaaaga
     6661 cgcaaacgct gcggaataat aaaaacgctg ataactcaac gtttagcaga ctatctgata
     6721 gggatagtct gtttttttat gttttttgcc aatttaaaac ttcgtttgat gctgaaaaag
     6781 tcgtaggatc ataatgcaca aaacaatgaa aaactagtat atagttttaa ttatccactt
     6841 gataaaaaca ccttatatta acgaaatgaa gaggggttat ttcgaagtaa aaaaccattt
     6901 acctaaaatt agaagctaag ctttcctttc aaggaaggct ttttgttttg ttatagactt
     6961 gcgattgttt gtgagctaga tcgttcattt taatgactta tacacgcgga tgatgggtct
     7021 ttttcctctg ttcattcata atattgaacg gtacagctag cgatgctata ctgacctcag
     7081 ttccaagaaa acgttaacat tttttgtggg ggagaggttt tttatgaggt ttgatcaatt
     7141 gatcgcagaa gaactgattg ttttcgatcc atcgatagat tcaaaaggat cattatttga
     7201 gcgaataggg gatgtgttga aaaaaacaaa taaggtaaga aatgttcaaa aagtcgttaa
     7261 ggcactattc aaacgagagg aggagatctc cacaggaata gaagatggat ttgggattcc
     7321 ccatgcaaaa agcaaatatg tgacaaaacc agcactgtgt ttttttcata cagccaaatt
     7381 aacggactat agcgggatag atgaaatgcc aattgaatat atttttgcca tcgtagttcc
     7441 tgaaaaatca gcagatatgc atctagagat tctcagcaca ctctccagac gattgatgaa
     7501 tgcagatttt agaaagggaa taaaagaagc cactacgcca gcagatatca tcagacagat
     7561 tagtcaagaa tgaaaatagt agagtctttg tccgagtatc gatagtgaag aaaaaggagg
     7621 aaaataatca tgaaaatcgt tggtgtaact gcttgcccga ctggaattgc tcatacttat
     7681 atgtcggcag aaaaattaga agtaacagca agaaatctaa accatcaagc aaaattcgaa
     7741 acacaaggtg taaaaacaga aaatcagtta tctgaacaag aaatcaaaga ggcagatgca
     7801 atcattcttg cagtagataa agaaatcgaa ttggaccgat ttgccgggaa aaaagtaaag
     7861 cgtgtctcta caagccgagc aatcaaagaa ccgcaagtag taatagacga agcattgaga
     7921 gatattggcg tattcgttgt gtctaatgaa aaagaaccag ctgcaaatga gaaaaagccg
     7981 acaatctata atcatttcat gaatggtgtg aattacatgc ttccatttgt gatcgcaggc
     8041 ggaatcatca tcgcactgag ttttgccttt gggattacag cggctgatcc caactcagca
     8101 gactataatg tgttagcagc tgcattttca aggatcggag gagatacagc gtttgccatg
     8161 atggttcctg cgttaggcgc ggggattgct acatcgattg ctggaaaagc aggttttgcc
     8221 ccaggaattg ttgccggatt actggcctct acaggtggtt caggttttct tggcggaatg
     8281 attggtggcg tgctagcagg gtatatctgt gattttctgg caaataaaat tagcgtaaaa
     8341 aaagaatttt ctgctattta tcagctgatt gtcgtcccct ttttatcgat cttaattatt
     8401 gggcttttga tggtatttgt gattgaacaa ccgatcacat gggtgttgga tgctttgaca
     8461 aattggctga atagcttggg aaatacatcc gggctattgt tcggattact tatcgggatc
     8521 atgatggcag ctgatatggg tgggccgatc aataaatcga cttcgacttt ctcgatcggt
     8581 ttgatgtcag ctggagtaaa tgcaccgatt gctgcttgta tggctgcagg aatgacacct
     8641 cccctaggta ttgctttagc cactttatta ttcaaacata aatttaccaa agaagaacgg
     8701 acttcaggtc aatcatgctg gattttaggc gcttcgtata ttacagaagg tgctataccg
     8761 tttgcggtat ctgacccgat ccgcgtgata cctagtttga tgacaggttc agcagtcgct
     8821 gcagggattt ccatggcagt aggagttact tcaatggcac ctcatggagg gatttgggtg
     8881 atgctaattc caaatgttat gaacaattta cctatgtatg tcttggcaat tgcatcaggt
     8941 acagtcacta cagcctttat gcttggacta ttgaaaaaaa cagtgaaaga gaaaaaacaa
     9001 gacaagtgga cgaaaaatga aaatctaaca aatgaggtgg aagcgtaatg ttatatacaa
     9061 tgaaagagtt attgaaagtg gctaaagaga atcaatttgc agtaccagcc ttcaatattt
     9121 gcagctatga tatgatgaaa gcaatcatcg aagaagcaga gagattagaa gcaccagtaa
     9181 tcttagaaat tcatcctgat gaaatcgcct atttaagtga tgagtttgtt gcggcagtaa
     9241 gagcctatgc ttatacaagt aaactgccga tcgttatcca cttggatcat ggcggtacga
     9301 tagaagatgt cttacgggcg attcgaaacg gctattcttc cgtgatgatc gatgcgtctt
     9361 tgaaatcatt cgacgacaat gtacagatta cgaaaaaagt ggttgcgtta gctcatgcgg
     9421 taaatgtctc agtggaggct gagcttggaa cgattgggaa taatggttct gctgaaggag
     9481 gtgctgaaac aatcatttat acagatcctg atcaagcgaa gatttttgtg aaagaaacag
     9541 gaatcgatac acttgctgta gcaattggaa cagcgcatgg cttgtatccg aaaaacagaa
     9601 ctccaaaatt aaatatcgac ttactgaaag aattgaacca acaaatcgat cttccatttg
     9661 ttttacatgg cggttcaggt aatccggacg cagaagtcag cgaagcagta aaatacggag
     9721 ttgccaaagt gaatttgagc tcagatctta aaagcgtctt tttcaatgct ttgagagaaa
     9781 tattgagtga aaatccatcg atgtacgagc cgaatgcaat ttatccagca gctaataaaa
     9841 aggtacaaga agtggtcaaa cataaaatgg aaattttgaa cacagtaggc aaggctagtt
     9901 tatactaaaa ataaaaatgt gtggtcaaga gggtatgaca atagtcttgt cataccctct
     9961 taaccacaca cgatgttcag aagtagtttt ttcgaaaaat ttcttcttat ttctcgaagc
    10021 caatcacttc tgtcacaacc tcttttttcc tgttactata taaagtaaat ggggtgattt
    10081 tatgttgaat gaagtggaga atagacagca ggagattgtg aattatctaa aaaacaacca
    10141 atttgcaaga gtcaccgatt tgatcgagtt agtaaattat agcgaagcca cgattaaacg
    10201 tgaccttgtt tttctggaaa aaagtggatt gatccgtaga gttcgcggtg gcgccatgct
    10261 tattgacaat cgaaaaattg acgtgcctta cctgatgaag atcaccaaat tagaagaaga
    10321 aacagaaaaa cgtaagattg cagatacagc ttcttctttg attcgagatg atatggtctt
    10381 attcttggat tccagtacaa cctctttaca cttagtcaga aacctagcaa gatttgatgg
    10441 tttgcagatc attacgaatg gcatcgtcac agctgctatg ttgagtgaat atacaacggc
    10501 aaaagtatct gtattgggag gggcaattgt tccgaaacga gcaacaatca acggttcaaa
    10561 agcctataac gatgcattgt catattatgc ggatttagcg ataatgagtt gtcgcgggct
    10621 agatttcagc caaggagtaa cagaaactca tgaaggagag gcaatggtca aaaaagcttt
    10681 tagaaaacaa tcagaccggc ttgccgtttt agttacacag caaaaaattg cacataaatt
    10741 catgcatcaa gccattgctt ttcatgaaat cgattatctg gtgacaagta aagaactgac
    10801 aaaagaacag tatgcgaaag taaaggaaca ccatatcgaa tgtctgtacg gataaattat
    10861 tacgtgaatg ttctaagtgg cttcctcatt tttagatagg accttatctt tgctcgcttc
    10921 tctcagccga tggtataata atgaaaaggt tatcttgtta gataatctta cttttttatc
    10981 caggagaaag gagtgcagaa aatgaaacat gtgaaggcgt tggtagtgaa ggcaatcatg
    11041 atctgggcga ttctgtgggt cgtgctgaca ggtttatacg gtgttagctt tatggattca
    11101 acgattgttg gggtaattat tgtagtcatg atctatgtgc taggggatct gttgatctta
    11161 cgtaaagtag ggaacatcgc agcgacgatc gcagatgctg gttcagctgc agttatcttg
    11221 tggctctatc tatattttat gaatgataca gtcgatattt ggatgaaagt attgattcct
    11281 gctctattga tcggtgtggc agaatggttc ttccacaagt ggttgctaag tcaaggcatc
    11341 gtaccagatg aacggaaaat ggaataaatc aacagttaaa ctattcttat cgataaatga
    11401 aagctttaaa aataaataga tgtttaatta agaataatca taaactattt ttactcaaaa
    11461 aaccgctcag attattttca gatctgaacg gtttttttta tctattcatc aagatcaaat
    11521 ttcatttttc aatgattcaa tcaattcgcc ctctgcttca tgactatgtt ttcggccatt
    11581 aacaagatag agtgctgtac atatcaatgg aatgactccg gcaatcacat acaatcctct
    11641 aaatgaagta agagatttta gcatccccat caaataagga ccaacgccta agcctaggtc
    11701 taaaccaata aagtaggtag ataaagcaat actgattcga tgttcgcgga cgatttttaa
    11761 acaaacagcc tgtccatttg acataaacgt accataacct aggccgacta atgctccaga
    11821 gataagcaat gtcacactat tcgtcgttac actcagtaaa aataatcctg ctgttaagaa
    11881 taaatagcta ggatacatca cgtattgttc tcctttgaca tcgaaaatcc ttccagtcaa
    11941 tggacgtgta aatgtgatga ccaaagcata tacgacgaag aaaaatgacc cagcagcaac
    12001 taagtggatt acttttgtat aagaagataa aaatgataaa acacttgaat aagaaagacc
    12061 catcaaaaag gcaattcctg taatgaaaag tgctttcttt tcaataaaac tattgatatt
    12121 ccatgagcga agagatattt tttgttcttc agataatgga atatttttta caggaaagac
    12181 aaggcaggca atcgtaacaa agaagaccag tacaattgaa aaccagataa tgaaacgaaa
    12241 atcagtcata ttcagcaaaa tcattcctaa aaatggccca acagcggcag ctaaactagt
    12301 acttaatcca taataattga tgccttcccc ttttttagat gcagggatat atgcagtaac
    12361 gatagcattt gtagctgtag aaactgtacc gtagccgaat ccattcaaga atcgaactaa
    12421 atacaatgcc ccgatagttg gcgtataaag atatgctaat gttgaaagga gatagaagat
    12481 cgcgccgcct cttaaggtaa acttccgacc aaatagttct aactgtttcc ccatgaataa
    12541 gcgtgccagc aatgttccga tgatatagat cccagaagca aaacctgctt ggctcaagct
    12601 ggcgtgtaag gtgtcttgcg caatgactgc catgatgacc atcaacagat aataaatcag
    12661 gtagacaata aaattgatca atgtgattcc aataaaatat ttattaaata atttcttttc
    12721 catgtatgtt atacattccc cttaagctga atatgctttt aatttttgta tttgaacttc
    12781 tacatcgtga taattggatg gatagcgatc aacaagttgg cgaataaata aatctcttgt
    12841 agacataaac agatttaaaa attcttcgca ttcgtttgtt ggattctcat ccactgcttt
    12901 gatcaattcg atcgagtttt gatacgcatc atttaaaaag actaaagaag ctttcatatc
    12961 aaatcttgtt tgatatgctg tttctaatcg attaatgatt gtgttcatcc agtaattcat
    13021 gttttttccc tctattctta aaaaatttta cttctgcagt ataacgaata aaaaaaagga
    13081 aaaaaatcgc ataagtgatg gaaaaaggta cttaacaaat gttaatatca ttagtaaaat
    13141 acctttggac tttaaaaagt tttaaagtac tgtatgatct ttttagatga aagtttggat
    13201 gggggagcat cattggatag tagagtctta aaggaatatt tggataaaaa tgattttccg
    13261 attatacgca aaggatatca taaatatttg acattcgaag ggatggaaga ttcccatacg
    13321 tatatcttga aagagggaac ggtaaaagca agtgttattt caaatgatgg gagagaattt
    13381 aaccttcgct atatcaaaga tcttgaaatc gtctctcttt taaaagacga atattcacaa
    13441 ttcatcgatt cgccgtataa tattcgagtt gaatcagaat atgcagagtt ttatcgaatc
    13501 aatcgtgtgc gcttttggca aaatatcaac caagacccaa agctacaaca ctatgtaaaa
    13561 gagtattacc gctatcgtct gctttattcg atgaaaaaaa tgcagcaaat gctattaaac
    13621 ggaaagctgg gagctgtttg tacgcaactt tacgaattat atgatttatt cggtgtgcgg
    13681 acagaagaag ggatgctgat cgatttttcg atcacgaatg aagaaatcgc caaattttgt
    13741 ggcatctcaa ctgctagcag tgtaaacaga attttaaaac aactgaaaaa agatggtatt
    13801 atcaccgtta aagaccatca tatcgttatt ttgaatatgg acttgttaga agacaatatt
    13861 atcttttgat gaacaaagag gttgtgaaat cagcgttttg acctgagtat tagagaaaca
    13921 aacggaaaaa tagttcctca tattttgccg ttttttgagc taataccgag ggtcagctga
    13981 ttgaacaccg tttaccaaga ggttgtgagc ctgccgttta actctgagtc acaaggaaca
    14041 atttcaaaaa acagcttttc atgtttgatg aatattgtga cttgtgaccg aggagttggt
    14101 aggagaacac cgtttaccaa gaggttgtga aaaagctgtt ctgcatcaag taataagaag
    14161 agccaagtaa aaacagtctc ttatgttttt aacttggctg gacttatcac cgtagatgta
    14221 agcttttgaa cgccgtttat ttgcaacaaa aggggctgtg acacgatttt tgtcacagcc
    14281 ctttttttgc gaacattcat ttagcaattt ttagaaactt ctgccgccac cgccaaaagt
    14341 cccgccaccg ctagaatggg tagtacttcc gccaccgccg cttccaggag gtgggctttt
    14401 ggggattctt cttgtcgtga caaaagaatt tgtcagacga tcggtttttt cagttaattt
    14461 gatactggat ttttctcgga atggatattt gtagatgcct gatttcaatt gataacgcga
    14521 aacagtcaca aaataaaaga caagactaag gataagagcc aaaacaacag caatgatgat
    14581 ttctactgtc gtcaaaacct tatagcgtgt aattttgcca gtttcttcgt ctacacgata
    14641 atgtcctcct ggaactccgt cttccacata tgttgctgat ttagacaggt aagcttttgc
    14701 agcattgtaa taggcagcat ttgtcatctg atcataaaca tcatctaaga tcgaatcgat
    14761 tctgctatca gtcaaataat cgatcatatt accagaagtc gaaatgtaga tttcacgctg
    14821 tcccatatct aatagcaata ctgagccatt ttgatcattt ccgactgcgt ctcttaagta
    14881 attatcagca aagtctcttg gttcttctga attagatgta gtcgttacga tcaagactcg
    14941 tcctttgatt ttttcattca gcttttctgc ctgttgttcc aaagattgga tttgatctgt
    15001 tgtgaataac ccagcctcat catttaccgt agctgtatct gcatgagtag ccaccggcca
    15061 gccaacactt actagcaaaa gaaagaataa aaaaaacttt ttcatcatat caagtaacct
    15121 ccgatcagaa agaggatcgc tagcccagcg aaaatcccaa gagcggtcag tcccaatttt
    15181 ttctggctga tcggcaggac accgctgacc tttcctgttt gtccattcat tgcgtagtag
    15241 tagacttttt tacttgagtc attgcttcga taagtaacaa gccataccgg cagtaatacg
    15301 taattattta cttcgtttgt gattgaagca gaagttcgca caccggtcaa tgttgtatat
    15361 ccatttgcgg tatcttttaa cagcttctct gaatagtctt ttaattcaga ttgaatctgt
    15421 gatttgattg cctcatattc gatatctctt ttttctgctt ggaacccggc taaatactgg
    15481 cttttaaaat caattgcttt atctaacggg aaaggttgca cgccttcgac catcttttgt
    15541 tgcgtatttt ttgataaggc attttttact agttctttaa aagaaagctt gcctgctctt
    15601 gaaacagcaa attgcttcgt ttctgtgtat tcgatgtcac ctatccgcca tatgcggata
    15661 actgtaccat tcgcctgcat ggcaccatct acttcagcat ctgtagccca ataagggaaa
    15721 tacacacctg tcaacttatc gatttgatcc ttattgaaaa aagctttggg aacaaaccat
    15781 tttttcttgg tccaagcgag aaatctgttg attgcttctt ctttctcgac agcaaaagga
    15841 agtactttat ttggcaagaa ttctccgctt aaacgtcccg atagtacgac gggattatgg
    15901 cagtagtaac aataagtcgc agcagttgtc gcatcagtca cgatctctgc accacagttg
    15961 ggacaaagaa aaagatctat cgctgcggta ttatctgcag attcgtccgc tgtatctgaa
    16021 aaaccgcctg cctcgtcaac cgctttgcgc tcggcttcat tcatatcggc aagctgttct
    16081 tgggctgtaa aagtaaaatc ttcggtaggt gaaggttctt ctttgctttc ttcgccagcc
    16141 atacgcgctt ctttttgctt ttgctcatat tggctgactt cttcttctgt atagatattc
    16201 aggcagtatt cgcaatgaaa tttttggtct ttgggatcaa aagtcaacgg accgccgcaa
    16261 ttaggacatt tatgtgtaag aacatccatc agctgcacac ctttctaaat aaattaatta
    16321 acggggattc ctttaaacgg tttaccacag tttggacaga atttagggat gccgttggaa
    16381 agatccacga tctcattgca ttcactgcat cgcatttgta gcttaggctg aacgttttct
    16441 acaggtttgg cagctccgca gttggaacag aattttccgg aattttctgt cccgcaaact
    16501 ggacatgtcc aagtatccgc atttccttgt gcagtttgtt gattttgttt ttctgcttgt
    16561 tgtttgattt gttcttggtt attttgagct gcttgagaaa gataagaacc atttgcattc
    16621 attcccatac ctacacccat aaagccggtc attgctcctg cttcattttt tccggctgct
    16681 tccataccac gtgcaatgga accttgcacg tatccttcac gtacgctagg atcacctagc
    16741 atcgcccctt cgttacgcat attgatcagt ttcacagaat catcggtgta agaaatgctg
    16801 gctacagcca cagaaacaat ctccatccca cgtaattcac gccaagaatc atccaatgca
    16861 gtatccatgt atttgcttaa ttccaaactc ttagatggta cataagaaat ccgttgacca
    16921 tctgcagaca tctgattgat tgctgattgt agcgctgtta ggaattcagc taaatactgc
    16981 tcattgatat cattgatttc cacttgtgtt ttgtttttag ggattgcgtt tgtataaaat
    17041 aaaatcgggt caacgacatg aatagaataa gtgccatgtg cccgtaagaa taattctgcg
    17101 ttatagaaat tgtcaaagta gttcaacggc gcgcttgtac cgaatttgat tccctttatt
    17161 tcttggagat tgatataaaa aacttgttgt ttctgcggtg tgacgccgcc aaatttgaat
    17221 cggtcaaaag tttcagcaat tgcttctttc agtgttccat tgaacatgga aggagctgcg
    17281 tcatttttaa tggtgtaata accttcctca gcggtataat cgatgatttt tccaccatcg
    17341 accaaaagca tcatcatgtt tggatagaca tggacgactg ttccgtctgt taaaacatct
    17401 tctgttcctt tacgattgga gccacgtttg tcatctttgc ggactttgac accttttgtc
    17461 atgaccgttg tatcactcat attgtctggt tcgatgactt ctagccattg atctgccaga
    17521 ccgccgccaa ccatacttgt tgctgctttg ataagaccca taaaaaattc ctcctctgat
    17581 tcagctagtg ccaaacaatt attgtttatt tattatacca taggaagatg tgaaacttct
    17641 cggactagag acggaattga aatggaaaat tgcgtattgt ttaaatacct gaaaaagccg
    17701 agaaggatag tagttttttt acctaatatc acgtataata agagatagtg aattttttaa
    17761 aaaaggggga tccttatggc atatcaagca ctttatcgag tctggcgttc gcagcgtttc
    17821 gaagacatcg ttggacaaaa agctgtgaca cagacactaa aaaatgctat tgtttcccac
    17881 aaaacctcac atgcctactt gtttacagga cccagaggaa ccggaaagac gagtgcagca
    17941 aagattttcg caaaagcaat caactgtccg aacagtaaag acggtgagcc atgcaacgaa
    18001 tgcgaaatgt gtcgatcaat tactgctggt acgcaagaag atgtgatcga aatcgatgct
    18061 gccagcaata acggagtcga agaaatccga tttatccgtg atcgggcaaa ttatgcgcct
    18121 acaaaggcag cgtacaaagt gtacattatt gatgaggtac atatgctttc aacaggagct
    18181 ttcaatgcct tgttgaaaac attggaagag ccaaaagaaa gtgtcatatt catcttagca
    18241 acgaccgaac ctcacaaaat accagctacg atcatttcac ggactcagcg atttgatttt
    18301 aaacggatca atacggcaga tattgtcgaa catcttgaat ttatcttgaa agaatcgact
    18361 atcagctatg aaccagctgc attgaatgtg attgcccgtt ctgcagaagg cgggatgcgg
    18421 gatgcattga gtattcttga tcaggcaatc tcgtttagtg aaggaacaat tactttagat
    18481 gatgccatgc aagtgacagg tagcttaact gacgaaatga tggacagtta cttgagtgct
    18541 tgcgtgaaaa aagaagtacc agaagcattg gaaacattga accaaattct cgcagccggc
    18601 aaagaatcac gtcgctttct agaggatatg ttacaatact gccgtgactt gctgatgtat
    18661 cagcaagcac ctaacctagt tgaggaacaa tcgagtacga tcagaagtac atttacagaa
    18721 ttggcacaaa ctgtttcagc ggatcagctg ttttcaatga taaagatttt gagcgatact
    18781 caaaatgaaa ttcgttttac caatagtgcc gctatttatt tggaagtcgc tacagtcaaa
    18841 cttgcacagc taccgtctgc ttctgttcct tcagcagatg tagcatttgc agatgatcag
    18901 atagtaaaac agctacaaca agagattaag gaactaagaa acgaaatcaa ggaactacgc
    18961 agtaatacag gaattgagaa tacaaaagta cagccggtac agcaaacaaa tcataaaaaa
    19021 cagacaagta cctatcgtgt accgacggaa cgagtatata aagttctgcg ggaagcgaca
    19081 agacagcatc tgaaccaagt aaaagaagta tgggaagact tgctgatgag tctatctgtc
    19141 actcagcgag caatgcttaa agcaagcgaa ccagttgcag ctggacctac aggactagtg
    19201 attgcgtttg attatgagat tgtttgtcaa agagcagcaa atgacgaaga attgcagctt
    19261 tcggtacaca acaacttaag ccgaatgatc aaagattatg cgcctgatcc tgtttatatt
    19321 acaagagaaa gctggccaga acttcgaaga aattatttga cgcaggcaca agaagaggga
    19381 acagaaaact cttttgcttc tgaagactca gaaggagaaa tcgagttgct tcctcaagaa
    19441 caagaagtac cagaagaaac acttgtagta aaagcagagg aactgtttgg ctccgaagct
    19501 gttacagtgg tagatgatta ataaaaagga gtagataatt atgatgcgtg gaatgggcaa
    19561 tatgcaaggc atgatgaaac aagtacaaaa aatgcaaaaa gaaatggcag aagcacaaga
    19621 gctgctaaat aaaacagagt ttacaggtaa agccaccaat gaattggtca aagcggtttt
    19681 tacaggcgat cgtcgcatga aagatatcca aatcaatgaa gaagtcgttg atcctgatga
    19741 tatcgagatg cttcaggatc ttgtcgtaat ggcagtcaat gatgcgatcg cacaaattga
    19801 tgtggaaact gagaaaaaat tagggaaata cgcaaaaggt ttgccaggat tttagtttta
    19861 aactgaagga gtaatgaata tgcaatatcc agaaccaatt gcgaaactga tcgacagcta
    19921 catgaaactt ccaggaatcg gtcagaaaac agcgacaaga ctcgcctttt atacgatcga
    19981 tatgaaagat gaagtagtaa atgaatttgc taaatctttg ttaagtgtaa aacgcgattt
    20041 gcatttttgt agtatctgcg gaaacatcac agaagaagat ccctgcgaaa tatgtagaaa
    20101 tccttcacgt gatcgaagcg ttatcctagt ggtcgaagag ccgaaagatg taatggcaat
    20161 ggaaaaaatg cgagaatatc acggacttta tcatgttctc catggtgtgt tatcaccgat
    20221 ggaagggaca ggtccagaag acatcaatat ttcttctctg ttgcagcggc tgcatgatgc
    20281 agatgtaaaa gaagtgatta tcgcaacaaa tgcaacaaca gagggagaag caacagctat
    20341 gtatctctca cgtctgatca aacccgcagg tatcaaagtg actcgtctag cacatggtct
    20401 gtctgtaggc tctgatatcg agtatgcaga tgaagttact ttattgaaag ctgtcgaagg
    20461 aagacgtgag ttataaattt ctaattaagt gttttttcag atacaatata aaagcagcac
    20521 aagagatggg ggcaacaatg tgaacggact atttattaca atcgaggggc ctgatggtgc
    20581 aggaaaaacc agcatcttga atgaacttta ccctcttttg aaagaagtag caaaaacaga
    20641 aatcattcaa acaagagaac caggaggcat tccgattgct gaagagatcc gagcagtgat
    20701 ccttgatcca aaaaatgatc ggatggatga acgtacggaa gcactgcttt atgcagcagc
    20761 aagaagacaa catctagtcg aaaaggttct gcctgctctg gcaaaaggga aaatcgtttt
    20821 atgcgataga tttgtcgaca gttctcttgc ttatcaaggt gcaggccgac gcatcggcgt
    20881 taccgagatt gctcggttga atgagtttgc tacagaaggt actacgccgg attttaccct
    20941 ttatcttgac gtagattcag acaccggatt aagaagaatc aagaaaaaca gacaaaatca
    21001 aatcgaccgt ttagattcgg aaggtttgga attccaccag cgtgtacgtc atgcttactt
    21061 aaagctggca gaagagaatc cggaaagaat ccacaaagtt gatgcaagaa aaagctttga
    21121 agaagtgctg caaacaagtt atcatacaat tattgaacag tatccgcaat tttttgaaaa
    21181 ctaggaaggt gaacgtttat gaaaattatt ttagcgatta tccaagacaa agacagcaac
    21241 cgtttatcaa atgaattgat tgatgcaaat atccgtgcca caaaactatc atcgacaggc
    21301 ggcttcctta aggctggaaa cagtacgttt atcgtgggta ttgaagatga ccgtgtagaa
    21361 gaagcattgg aaatcatcaa aaaaacgtgt gaatcaagaa agcaatttgt atctacacct
    21421 gttacactgg atatttcgat ggatgggggc gtcccttatc cagtagaagt agaagtaggc
    21481 ggtgccacag tcttcgtctt acctgttgaa ggattccatc aattttagga ggagctgagc
    21541 tatgaatcaa gaaataaact tggctcaaat gcaaccgatc gtgtatcagc agcttcaacg
    21601 gagttttgag catgggcgta tcgctcatgc ttatcttttt gaaggggaga aaggaacagg
    21661 aaaacatgaa gtaggtatat ggcttgcaca gcacctgttc tgtacccaaa tgaaagacaa
    21721 tctgccttgt ggaaaatgca acaattgtca gcggatcgaa aagaaagaac atccagatgt
    21781 tttggttatt gaaccggaag gacaaaccat caaagtcgat cagatcagac gtttgcagac
    21841 ggaattcagt cgcagcggtt acgaatcaag aaaaaaagtt tttttgatca aagaagctga
    21901 aaaaatgaat agcagtgcgg caaacagttt gttgaaattc ttggaagagc cccctggaga
    21961 ttttttagcg gtgttagaaa cagatgcagt aggaagaatt ctccctacta ttcaatctcg
    22021 ttgtcaagtt ctgcattttc aagaactttc gaaagaagca ctgatccatc gattgcaaga
    22081 agagcagatt ccattggaaa aagcaaaact tttggctttc ttaacaaaca gtttaggaaa
    22141 agcagttgaa atctctcaag atgaatggtt taatgatgct aaggacttga tttatcaatg
    22201 gttcgtttac ttgcaaaagc aagatactca agcctttatc tatgtccaaa aaaaattggt
    22261 aaaatcattt aaagaaaaaa cacaacagtt tacaggatta tctgtcttga tgttttatta
    22321 tcaggaagca cagcgtcaag cagtagcaaa cggcgaatat ggcaaagtga aacagataaa
    22381 ccagataatt gaacggatat tgatcgcaga gcagaaacta cgcagcaatg tcagttttca
    22441 ggctgttgcg gaacagttcg ttttgcatac gattttttag cttgccgcaa aggatgatga
    22501 tcaaggagga tggaaatggt agaagtagta ggtgtccgat atagagatgc aggtcatatc
    22561 tattattttg caccaggaga ctctgaatat gtttatagtg acaaggtatt agtcgaatct
    22621 cagcaatcct tacatattgc tactgttgtc cttcctaaaa aagagattga tcccaatgac
    22681 cttcctgaag ctatccgtcc gatcttgcat aaagcgtcac aagctgaatt agaaaaagac
    22741 aaaaaaaaca aaaaagatgc ttatgatgca ttgaaaatcg caaaagaaaa agtgcagttg
    22801 cgtgagttgg aaatgaaaat ggtcaaagcc gaatacacat ttgatcgaaa taaattgatt
    22861 ttttctttca cagcggacgg gcgaattgac tttagagaat tggtaaaaga tctggccgct
    22921 gtatttcgta ctcgtattga gcttcgacaa attggtgtcc gcgatgaagc aaagataata
    22981 ggcggaattg gtccatgtgg gcgtccatta tgctgttctt cttttttagg cgatttcgtg
    23041 cctgtatcaa tcaaaatggc aaaagatcaa agtttatctt tgaatccaac aaaaatttcc
    23101 ggtttatgcg gacgcttgat gtgctgtctg caatatgaga gcgaagaata cgagacagcg
    23161 aaaaaagaac tccctgactt tggaaaagta attgctacac ctgatggtaa agggaaagtc
    23221 gtagggttga atctgcttag ccgtatcgtt agtattcggc tgactggacg ggaaaatcct
    23281 gtcgaatatg aatgggatga attgaaagaa tttatccaag taggtgagat gaatggataa
    23341 gagatcatta tacgacggat tgaatcaatt agaatcagag ttgagaaata cattaacaga
    23401 acttgttgaa atgaagcatg ctttgcatga gatcgtagaa aaaaatacaa ctttggagat
    23461 ggaaaatcaa cgtctgcggg aacacctgcg ggaattgaac caagttgcac aagctccagc
    23521 tgaaaatgtg aagcaggaac tttctaagtc tcgtatgaat cttgaaaaaa tttatgaaga
    23581 aggattccat gtctgctacg atttatatgg atcaagaagg gacaatgacg agccttgtgc
    23641 gttttgtcta gaagtgatct atcgcgaaag cggtcgatga ccaataacaa gaggagactg
    23701 gagcggagaa atactgctcc agtcttttta ttaaggagat tgtgacagat gtataatcaa
    23761 aaaagtttca agggaaatcc ggtatatggg gatttatatc ttgtaccgac gccaattgga
    23821 aatttagaag atatgagcta cagaagtgtt cgtatgctgc aagaatccga tcttatcgca
    23881 agtgaggata cgcgtaatac acaaaagtta ttgaatcatt ttgaaatcca tacaccccaa
    23941 aaaagtttac atgaacataa ttataaagaa cgtgtccctc aattgattgc tttgttaaaa
    24001 gaaggaaaaa cgattgctca agtcagtgac gcaggaatgc cttccatcag cgatcctgga
    24061 catgagctag ttttagcctg cataaaagaa gggatttctg tgatctctat cccaggacct
    24121 acagctggga tgacggcttt gattgcttca gggctagtgc ctcaaccatt tttattttat
    24181 ggcttccttc cacgtaagaa aaaagaacag aaagaaacat tgaaaaagct aaaagaacag
    24241 acagttacgc tgatttttta tgagtcacct tatcggatca ctgctacatt gacgaatttt
    24301 ttagaaattt ttggaaatcg ccaagtcgtt ttgtgtcggg aattgacaaa ggtccatgaa
    24361 gaatacctta gaggaagtac ggaagagcta ctcgcttata tcgaagaaca tccagtaaag
    24421 ggtgaatgtt gtctgcttgt agaagggaat ttgttcgaaa tgccagtgac ggaagttgat
    24481 gaagagttgg gaacgttaaa ggaacaagta gaagcaaaga tcgcttcagg cgaaaaacca
    24541 aatgctgcta tcaaagcagt agcgctgaaa aatgggctga aaaaacaaga agtctaccgt
    24601 cagtaccatg aattagactg agatagtata agttgtctat aatgaaagac taatgaggaa
    24661 atcagctact aacttttcaa atctcttgaa cgcgaacgaa tgttcttgta taatgaataa
    24721 gaggtgagga tgatggagct gcaatttcct ttacataatg atacatcaag aaaaatcatt
    24781 catattgata tggatgcttt tttcgcttcg gttgaagaac gagatcatcc tgagtttcgc
    24841 ggacatccat tagtaattgc cagacacccc agtgacactg gtgggcgtgg agtagtgact
    24901 acagcaaatt atgaagcaag aaaattcgga attcattcag caatgagtgc acaaaaagcg
    24961 tatgagcttt gtccgcaagc catctttaag cctggcgacc atcataaata cagcgatatt
    25021 tccaaacaag tacgggaagt attctatcgt tatacagata ttgtggaacc agttagtatc
    25081 gatgaagcgt atcttgatgt gaccgaaaat aaaatcaatt gcaagtcagc catcaaaatc
    25141 gcccgaatga tccaagcaga tatttgggag agtgtccagc taacatgttc tgcgggagta
    25201 agttacaata agtttttggc caaattagca tcagactatc aaaaacctag aggaatcacg
    25261 gtagttgccc ctcaagacgc tgtgccattt ttaaaagctt tgccaattga aaaatttcat
    25321 ggggtaggga agaaaactgt acctagaatg catgagctag ggatttatac aggaaaagac
    25381 ctatatgaat gcacagaaat gatgttgatt cgaaattttg gaaaaatggg ctattctctt
    25441 tatcgtaaag tcagaggaat ccatgattct ccagtaaacg ttacaagaga gcgaaaatct
    25501 gtgggaaaag agcatactta tgggcagccg ttgcaaacgg aagaagcagt gctgactcag
    25561 ttgcgccaac tagctgaaaa agtagaagaa gcactgagaa gagtccaaaa acatgggaaa
    25621 acagtagttt tgaaggtcag gtacacggac tattctactg tgaccaaaag agtgacattg
    25681 ccagaatata tctataaaaa agaagcactc ttttatcaag caagccttat atgggaggaa
    25741 atcttgggag tagaaaaagg aatccgattg ttagggatta ctttgacgaa tctggacccg
    25801 atgacttatg aaaacatcgt ccttccatta tgggaaaatc aagaaatata aaaacagctt
    25861 tgagagttga aaccggaaat ccgttttctc tcccaaagct gtttttatat caagtcttgc
    25921 tttttgattt gttcataggt ttctgttgca tccgtacatt tttcccaaat cacaacttga
    25981 ttggattcta aagatttttg gacgtcaatg atccgctggt tgctacttcc gcgaaattgt
    26041 agttttaggt cacgtttgct taattcaaag cgtccgtcaa caaggatatc gatttgcgaa
    26101 aggagttcta atttatcttc tgaatcttgt agcaattcat caaaggcata gcctgtccat
    26161 gaccagatat cttttgtcgt accgaactct tttcggatac gtcgtacgac ttgcagacaa
    26221 acatctgtat tcaaaaaagg ttcgccacca agtaaagtta atccttgcac gtaatcgttg
    26281 cgcaagtcag cgatgatttg ttcttctaat tcaggtgtga atggtttgcc atatcggaaa
    26341 ttttgtgcag ctttgttgaa gcagccttcg caggcaaata agcagccact aacgtaaaga
    26401 ctgttgcgga caccttcacc atcgacaaaa ttaaacggtt tgtagtcagc aatatagttt
    26461 tggctgtagt cttttgctaa ccattctttt ggttttggat ttctcataaa aaaacttctt
    26521 tcatttaagg ttcaaagata tagctattga agataaaatc tactcgacca cataaataag
    26581 aacaaactga cctaaatcca ttgttcaaga aagcttgttc ttattttgat agagggcgtt
    26641 caaagataca aagccatcga aagagggtgg tgaaaaaaga cttgtcatag cctcttattc
    26701 tgaataaacg gtgttcaaaa gcttgcatct gcagtaataa gcccaactaa acgaaaaata
    26761 tgaggaacta tttttgttta gctattctta ttacttgatg caggacagct ttttcacaac
    26821 ctcatttcat gtgtttcaca cgtgaggaaa tttctttatg gcggccatgt accatcggac
    26881 gagcttgcgg atttcctaaa tagccacaag tacgtttgac tacatcacat gtttttggat
    26941 catgatttcc acattctgga cattcgaacc ctcgttctgt cggtttgaaa tcaccttcga
    27001 aaccacattg atagcaatga tcgattggcg tattcgtacc aagatacccg attttgtcat
    27061 atgcaaaatc ccatacagct tctaaagctt tcggattttg ttggagcata gggtattcac
    27121 agtagtggat gaatccacct gaacaatatt ttggataatc cttctcaaat tccaattttt
    27181 caaatggcgt tgggttttta cgcacatcat agtggaaact gtttgtataa tattctttat
    27241 ctgtgatatt ttcgatgatg ccgaattttt ctgtatccaa acggcagaaa cggtcagtta
    27301 gactttcact tggagttgaa tagacactga aatgataacc atattcatcc ccccatgcat
    27361 ctgcattagc ttttaattct ttgacgatat caagtgtgaa agcttttgct tctgggtttg
    27421 tttcccattc gccaccgaag aaagctgaag caacttcata caatccaatg tagcctaacg
    27481 atacagtagc tcgacggttt ttgaataatt cattgacaga atcggtacgt gaaagacgtt
    27541 tcccgaaaga accatacata tataaaattg gcgcatttgc tggaatggct tctttacaac
    27601 gttctacacg atagagaagc gcatctttca tgatttctaa gcggtcagac agtaactgcc
    27661 agaatttatt ctgatctcct tttgattcga tcgcgattct tggcaaattc aatgtaacaa
    27721 cacctaaatt cattcgtccg acatttactt cttgaccatt ttcgtctttc cacccttgca
    27781 agaatgaacg acagcccata ggtactttga aacttccagt taattcaacg attttatcgt
    27841 aattcagaat atcaggatac attcttttcg ttgcacattc caatgctagt tgtttgatgt
    27901 cgtaattagg atcttcaggg tttaagttca cacctttttt caaagtgaag atcagtttag
    27961 ggaagatagc tgtccgcttt tcactcccta atccattgat tcgaatctgt aaaattgctt
    28021 tttgaatttc tctttcaaac cagttttctc ctagtccaaa tcctaatgaa gtgaaaggag
    28081 tttgtccatt tgaagtaaat aaggtattga tttcatattc caaactttgc atagcatcga
    28141 agatatcttt tttggttttt gcttttgcat attctttttg gcgttctggc gaatcgatcc
    28201 attcttccgc gtcttttaga tgttttttat agttcaattc tgcaaaagga gcaagcaatt
    28261 catctgttcg gtcggcagaa cagccaccat attgacttga cgctacattg gcaataatct
    28321 gtgagatttg tgctgtggcg gtctggatag attttggcga ttcgacttcg gcattgccga
    28381 ttttgaaccc attgttcagc atgcctttga aatcaatcaa gcagcaattc gtcatcggtg
    28441 tataaggatg ataatccaaa tcatggtaat ggatatcgcc tttttgatgc gcatttgcta
    28501 tatgtggtgg caacattttc agtccgattg attttccaac gatcccggct gtcagatctc
    28561 gctgtgtatt gaaaacatta ctgtctttat ttgcgttttc gttcacgaca gtttggtcct
    28621 tgttgattag cttttcaatc gaaaagttga tatctgttgc tttactgcga gcaaaatctc
    28681 gtttggtacg ataattgatg tactcttctg ctaattcata ttcgtttttt tctagtaata
    28741 tatgttccac gatgttttga atctcataga ttttgacatt ttcagcaaac cggcttttga
    28801 tttcttggac aaccaagtct gcaatcattt gaattttttc ataagtaagt ggtgataatg
    28861 agccgtgaat tttcttttct gctttgatca gtgcttcatt gatcttttgt tcatcgaaat
    28921 caacatggcg gccatcgcgt ttgatgactt tcatctggga tgtctctggc tgctgagtaa
    28981 cgacagtttt ttcttcataa tttactttca ttatcttcaa ctcctgctaa attgttcttg
    29041 tctatcataa aacaaaatcg gggaaggagc aactaaatat cggctatata tagtattcaa
    29101 tgtgctgtat aattggattt ctatactata tgtagtgtat attttattgt gaaaaaaggt
    29161 gaaaacttgt agctggtgga tttgtttttt gcatatttaa ttttgctgaa taaaataatt
    29221 gaataaaatt ttttattcag tccaagtaaa agtgacaaaa acataagagc aaattattcg
    29281 tagatatgct actatgcaaa taaatagaaa tgaaaaatga aagaggagga gaagaattgg
    29341 aaaagatgat cgaagtgaaa catctaagta aaagctacgg cagcaaactt tctcccgtca
    29401 aagccttaga taatatctca ttcacagtag aagaaggcga gtttgttggg attatgggcc
    29461 caagtggtgc aggaaagaca acgctgatga atatcttgtc cacgatcaat ttgcctacga
    29521 tgggcagtgt ctcgatccaa ggaaaagaaa tcacaaaaat gaaaaacagt gagctcagtg
    29581 actttcgtcg aaaaaaacta ggattcattt ttcaagagtt caatttgatc gataccctaa
    29641 atgcaaaaga caatatccta ttgcccctag cagttgaacg gatgactaaa gaggaaatgg
    29701 aaaagagagt aagacatgta gctcaattgt tgaatataga agaactgctc aaacggtatc
    29761 ccgatgaact ttctgtcgga cagagacaac gaattgcagc tgctagagca cttgttgttc
    29821 agccacaagt gatttttgca gatgaaccaa ctggctcttt ggactcgaag tcggctacag
    29881 aattgttgaa ctacttgaag accatgaatc aaaaagaaaa agcaacgata ctgttagtca
    29941 cccatgatcc atatacagca agctactgcg atagaatttt atttattaaa gatggtgtga
    30001 ttttttctga agttgtcaga agagggacaa gaagagagtt ctttgagaaa gtaatagaca
    30061 tgcaggcgac gattggcgga ggaggaaaaa tgaatgctgt ataaactagc cgttaaaagt
    30121 ttttttcggc agtcacgagg ctatcttgtt tattttttca gtttgacttt atccgtaatg
    30181 atctattatt ccttcagcgc aatgacctac gatcaatctt tagtcagaag agcaagtcaa
    30241 gatacttcga tagatggtgg attgagtttt ggtggattta tcattactgt tgttttgctt
    30301 tttttcgtat tcagtgccaa ccgatttttc ttgaatagaa ggcaaaagga aataggcatc
    30361 tatcagcttt ttggtatgaa taaactgcag atatcaggta tatatgtgtt agaaatcatg
    30421 ataattggat tgttcgcctg tatttctggg atattactcg gtattatttt ttccaaactc
    30481 ttttcaatga ttttggttcg aatgatggat atggatctta ctagtccatt ttttatctcc
    30541 attccatcag tagtagatac tttatttgct tttttcatca tccttttagc agtatctgta
    30601 tattcaatat ggaaaatatg gcgctatcca atgattcgaa gttttggaga aaaagaacaa
    30661 gcagatagtt caacaatgcg cttcaggaca aggcaccgat tactcgcagt catcgggtta
    30721 ctacttttaa cgagcggata ttttggagct agtcatttta gggaaatcac ttcatggatg
    30781 atcagttatc attatcttga tacattagtt ttcttttttc cttttttaat ttttttcgtt
    30841 tgtgtggtcg gtacttattt gtttttctgt tatacatttc ggttattttt gatcatattg
    30901 agtaaatgga agatttatta ctatggtatc aattttttga taatgggtaa cacgcaagtt
    30961 catttgctca aaagttggcg tacaaattct ctgattacag tcattctcgg aatttcttta
    31021 atgacaattg gcggcacggc tagtatctct actattttat cctaccagga gaaagtttcc
    31081 tccccgatgg actatcagtt tgatgttgag acagagaaaa aaatcaagcc gattctagca
    31141 gaggaagggc agaagataac taaagaaatc accttgcatt ataaagtcat tgggagtatc
    31201 tatagtcaaa atctcgaaga acctatgttt caaactgcta atctgatcac ggaaacacaa
    31261 tatcaagcct tcagaaaagt taatccagat ttgccgaaca tttctttgaa atcacctggt
    31321 catactgttt tgcttgatca aatgcaaact ctttttcgga atatttcatt atatggatct
    31381 agtattggac tgccagataa tcaagaattg aagattcaac aaatgcttcc aagtgtatta
    31441 ggtgacgaaa caatggtata tctaagtcct gtactgattg tagatgatac cgtttttgaa
    31501 aaagcaaaag gtgtggatta tcaagtagtc aatgtagatg tatcaggtgg aaataatgaa
    31561 aaaatagatg aacgactgag caatgacctg tcgataaagt ggctcaatgc tgtttattat
    31621 tcttatgata tcgtaaatgg aagtctacaa ggagaaatta gcacaaagaa acttccggat
    31681 gaccaaatga aggaagcaca atttagccaa gaaagctctc gtttgaattt ctcttccagc
    31741 tattcgaaat tgcgtgcagt taatcggcga atcggtatca atatttttgt cacactattt
    31801 gtcgggatga tcgtgattat tgctactggt agtattttga cagtccggca attagcagaa
    31861 gcagaggaag aaaaagaaaa ttatcaccta ttgactaagc tggggattcc acaaagaagg
    31921 atcagacgga tgatcttcga gcaaaacgca cttaccttct ttccacccat gatattaggg
    31981 atcactcacg cagtatttgc aatcaatgtc ttcactcagt atataaaaac tgccgattac
    32041 tggttggctt atcttgtgag tggcttattg atccttatct atcttttgct ttatgtcatt
    32101 acgagtcagt tatattgtcg gattatcgag gaatgatata cggaataaga caagataata
    32161 aatagaacta aattttgaat accatttatt tggaataaga ggttgtgaca cgatttttgt
    32221 cacaacctct ttatttttta tattttttaa aagtacgaga aattataaag aaaaaagcag
    32281 tgatttgatg tgctattttt ataaaagcta tgtgacaaaa ctgttagtaa aaaaacggtt
    32341 tctgtaagct agacacatgt ttctttttgt caaaattagt tacactttgt gtgaggttat
    32401 atgaggaggg aatccaatga acaaatggcg ttctaatcca aaattgaatt attggggaaa
    32461 attcatcatt cgaacaattt tttatagtgc agtactgctg ttcctgattt atctgtatca
    32521 ctataaaaat attcaaggag gaacttttat ctataacgaa ttttaggagg aagagtatgg
    32581 aaatcaaaac gattattgaa gcaatcgatg attggggaat aaatgaacct gatcgagttg
    32641 cttatcaggc ggatgagacg catacttttg gtgaattgaa acaagcatca gacgcacttg
    32701 cttattattt agaaaaaaag gtagaaggcg atggaccaat tgtcgttttt ggcaatttgg
    32761 agtttgaaat gattgtctca tttctagggg ttgtcaaatc tggccatgcc tatttgccga
    32821 ttgaagagca tacacccaag gagcgtatcc tatcgatctt tcgggtggct aaaccatcta
    32881 tggtcatcag tatcggggac tggatagaag atattccttc ggttcctgtc ataacaaaaa
    32941 aagaatttca agaaatcaag aagataccag taggatttta tcccagaaat agcgtaaaag
    33001 gtacagaaaa tttttatatt atttttactt ctggtactac tggagaacca aaaggcgtac
    33061 aaatcagtca tgataatcta gtcagctttg ttcaatggac gatggaagac tttgggatca
    33121 agcctggtat gcatttctta gcccaagcgc cattttcttt tgatttatcg gtattttcta
    33181 tttatcctgc attagtttct ggcggaatgc tgaagccgtt aaataaagca gttgttcaag
    33241 actttcgtca attattcgcg acattgccag ccttgaagtt gaatgtgtgg gtttctactc
    33301 catcatttat ggatatttgc ttgatggaac ctacattcaa tggagaaaat gtgccggaat
    33361 tggacatgtt tttattttgc ggagaagaat tgacgaaaaa aactgcagaa agtctacttg
    33421 atcgattccc aaatgcacgg atatataata cttacggtcc aacagaagca actgtagcta
    33481 tttcaagtat tcagattgac cagcatgtac tagatagtta tgaccgacta ccgattggct
    33541 acgtaaaaaa agacacgaaa gtttctattg tccaagaagg taaacctgtt tcaaaaggag
    33601 aaacgggtga aatcattatt gcaggaccaa gcgtatcaaa aggttacctg aacaatcccg
    33661 aaaagacagc tgctgcgttc ttttgtcaaa atgacttagc aagttaccat acaggggatg
    33721 caggtagact agatgaatat gggcttttat tttatgaagg acgtatggat cagcaggtca
    33781 aattacatgg ataccggatt gaactcgggg atatcgaaca ttatctgctc caagacaacc
    33841 gaatcaaaca agctgtcgtc gtaccaaaat accaaggaac aaaagtacag cagctggttg
    33901 cttttgtcgt attagaaaac aaaacgaaac agccggattt tcagttgact aaatctatca
    33961 aagaacaatt actagaagtt gtaatggatt atatgattcc tcagaagttc cattatgtcg
    34021 atctgctgcc tcagacagtt aatggaaaaa tcgatcgaaa aaaattaaca gctgaggtga
    34081 atcctgaatg atgttacctc atatgatccc ttatgcagag ccgttttatt tttttctttt
    34141 agccattgcg cttgtaccga tcgttctatc tttattgata tgggaaaaaa gattaccagt
    34201 ttatcaatca gcagtgacac ttttcttttt atttgtcagc tttggaggta attattggca
    34261 acagggagcg gcgctgattg ggtatgtttt gtggcagacg atacttgtat ggggctattt
    34321 tgtttatcgg caaaggaaaa atcagacagg atggtttttt gccgccgtta ttttagcgat
    34381 aattccactg tttttaacga aagtgactcc tttttttgaa catggaaaag catcgttact
    34441 tggtttttta ggaatctctt atttaacctt taaatctgta caaatgatca tggaaataag
    34501 agatggcatg atcaaaacat ataagccatt tcgttatatc cagtttctgc tgttctttcc
    34561 aacaatctct tctggaccaa tcgatcgcta taggagattt gaaaaagatc agctccatcc
    34621 gcctgttcgt gataaatatg ttgatctttt gggaaaaggc gtccaaaata tttttgtcgg
    34681 ttttttatat aaattcatta tcggttatta ttttggtcaa gtactgcttc ctgtagtggg
    34741 acgcattgcc ttacagcatg gtggtatttc atgggcatta gtaggttata tgtacgtgta
    34801 cagtatgtat ttgttttttg attttgctgg ctatagctta tttgcagtcg gtacaagcta
    34861 catgatggga tatcagacac caatcaattt caataaacct tttttatcat ggaatatcaa
    34921 agaattctgg aatcgttggc atatgacgct gtccttttgg ttccgtgatt atgtatatat
    34981 gcgattgatg ttcttcatga tgaagaaaaa attttttaaa agcaagatcg taatgtcaaa
    35041 tatcggttat tttgctttgt ttcttctaat gggtatatgg catggattga cgtggtacta
    35101 catcgtatat ggactgtatc atgcttgtct gatctgtctg acagatgcat ggatccgatt
    35161 taagaagaag cataaagagc agttgccttc taacaaattt acgcatggct tagccgtatt
    35221 tttgacattt caagcagtat gttttagctt cctgattttt tcaggatttt tagataaact
    35281 tttttttagc taacgaatag tgacatatta atttatataa caaaggagaa aaggaaaatg
    35341 gaagaacaaa ttttatcaat cttagaagaa ataacaggaa cagatgaagt aagaaaaaat
    35401 cgtgatattg atctatttga tgaagggttg cttgattctt tagcatctgt tcaattatta
    35461 gtcgagctag acggagagct ggatatccaa gtccctgtat ctgaattcga gcgagaggat
    35521 tggagcacac cgaataaaat cattcaacaa gcaactgcat tgaagggttg agtatgaaaa
    35581 agaaactttt tgctattttc ggcccggttg ttttagctgt tggcttactg tttgtgtttt
    35641 ttacctcctc ctatcaagta gatatctcta atccagaaac gattagacgt gcctcttctt
    35701 ccatgtcagt gaacgtgttg aaaggagatg cgataaaaaa ttatgcatta tctgaaaaac
    35761 aatatattcc tttttttggc tcaagtgaat taagcagaat cagtccattt catccgtctg
    35821 ttctggcaga aaaataccag cgaaactatc gtccattttt gctgggagca cccgggacac
    35881 aatcgttaag ccaatatatg atgatgcgtt ctgcaggaga tgctatgaaa aacaagaaag
    35941 tcgtctttat tatttctcct cagtggttcg ttaaaaatgg tgtaaaaact gattacttta
    36001 atacgtatta ttctgaactt caaacatacg actggttgtt ttcaatgaag aaagtaacgc
    36061 ctgctgatcg ctatttagct agaagattat taactttctc aaaagtaaaa gagaatgata
    36121 cgttgacggc gattctgcaa acgatcaaaa aagggaagct acctttacct gaatctttga
    36181 atcagctgcg cagccaatgg aacatgctga agagagagga tgaagtattc agcaatattg
    36241 ggttgaaaga tcgacagcaa aaaatcgatc atgagtcaaa acgattacca aaacaatacc
    36301 aagaaacaga attatccatt ttagcaaatc aaattggaga acgagaaacg acgaataatc
    36361 cattcgggtt gaaaaacgat ttttatacgc atcgtatccg agcccacgag ccagagctca
    36421 aacagtcaca aaaaaattgg gattatcgtt tttcgccaga attttctgat tttcagctgg
    36481 tcttggatca attagcaaaa aaccataacg aagtattgtt catcatccca ccggttaacg
    36541 agaaatggag cgattatacc ggactatctc aagaaatgtt acaaggattt gccaaaaaga
    36601 tcaaatttca attaaatagc caaggattca atcgaatagc tgattttgtc aatcaagcgg
    36661 gtaccaacta ttttatggaa gacacgatcc atctaggctg gaaaggctgg ttggctgcag
    36721 atcaacagat cagaccgttt ttagaagaaa atcatattac tgctagtaag tatcatcttg
    36781 acgatgcttt ttttagcaaa tcttggcaac atcaaatacc agataaacta caattaaaat
    36841 aaagaaaaca ggcgagtgtt gctcgcttgt tttctttatt tttgaatatt ctgaataaaa
    36901 gataaaaata ccaagtttgc ctgaacaaaa atcataagca atggtataat cacaatatga
    36961 atatagaaat gggggaaaac atttggatac aaaagaagaa cagctactta ttgatttaac
    37021 ttctgcaaaa ggagtacctg gaaatgaaga agaggtaaga gaagtattca gagaatatgc
    37081 caaaccattc gctgatgata ttttttatga cggtttaggc agtgtgattg ccaaacatgg
    37141 tgctggcgga ggccccaagg tctttatttc tggacatatg gacgaagttg gttttatggt
    37201 aacaaaaata accgaaaaag gattcttgga attccaaact cttggaggtt ggtgggggca
    37261 agtcatgctt gctcagcaag ttgaaatcaa aacacgtgaa gggaaaatcg tccacggtgt
    37321 gattggttcc aaaccaccac atgttttaac acctcaagta agaaataaac cttatgaaat
    37381 aaaggatatg ttcattgata ttggcgcatc aagccaagaa gaagccaaag agtggggcat
    37441 acgtcctgga gatatggtca ctccatatat tgaatacaaa cgaatgaatg gcagtaaata
    37501 tttactggca aaagcatggg ataatcgtat cgggacagct gtttctctgc gagtattaga
    37561 gaatctatct aaagaagcac acccaaatgt tttattcgca ggaagcgatg tgcaagaaga
    37621 agtaggcttg cgaggtgctc gaacaagtac acaccttgta aatcccgata ttgcttttgc
    37681 tttagatact ggtacagcag gagacactcc aggaatgaca ccaaaagaag cagattcgat
    37741 tttaggaaaa ggcccacaga ttttgatttt tgatgcatct atgatcccgc ataaaaaatt
    37801 attgaatttt gttattgatg tagcagagga aatggatatt ccattccaat atacagtgat
    37861 ttctggcgga ggaactgatg caggacaaat gcatttgaca agagatggtg ttccgtctgt
    37921 agccattacc gttcctgttc gttatctgca ttcccataca tcagtgattc atgaagatga
    37981 ttatttgaat acagtgaaac tagtcacaga attagtgaaa cggcttgata gtgaaacagt
    38041 tgaaaaaatt cggagttatg aataatgaat aatagaatac ctatttctga atatcggaaa
    38101 aaagcacgag tttctttgga aaatcaatgg ggaatcaata cttggcttgt tttcttatct
    38161 ataatattta cgagcgtcat ccagaacttt tttgacggtt tcagtccttt tccggaagaa
    38221 agcatgcagc agcacttatt gagttttcta gtcgataatt tacttttatt cgcattcaac
    38281 tatgcattgt tttacattgc gctagtagtt gtacggggtg gcagaccaaa aagtaacctt
    38341 ttattttcag ttttccaaag aaagtatttt ggttcgatac ttggcatcaa tttgatcaat
    38401 tcagtcatca actggctact caacagttta atctttctgc ccatgttttt aatcagcgga
    38461 gtgagtactt atatgcagct gcttttcagt tcaaatgcgg tacctacggg tgtcatgcca
    38521 gaagattttc ttgatatcag ctttgtttta tcgatgatag ggatgatttt tgtttcagca
    38581 ctcatcatga gtattgttgg cggtttattc caatttgctg catggacaaa gttcgactat
    38641 cctgatttgt cggttattca atgtttgaaa tatggctggt ttttattgaa agatagaatt
    38701 ggtacgtata ttttgttgca gctgtctttt atcggctggt atttgctagg agcaatcgct
    38761 ttgttcatcg gtcttttgtg ggtcattgtt tatgtgaatg tgtcagttgc agaattttat
    38821 gaacaagcac ggattgaaaa aggaggtcca gacgcctatt ttacttagca tgtaagcagt
    38881 ttattcatca aaaaaataac ttttgtggta ggataaatct ttgaggggga atgtacgatg
    38941 aaattaactg ttttaggatg cttaggagcg tatccttata aaaatcaagg gacaacaggt
    39001 tatttgcttc aatctgacgg gttcaatttg ttgatcgatg caggtagtgc tacgctgatc
    39061 aaattacaag aacaccttga tccacttgat ctagatgctg tgatccttag ccattatcat
    39121 catgatcata ttgctgacct tggtgtatta cagtattact ggcaacttca tcctaagaga
    39181 aatccggaga cattgctttc aatttatgga cacacaaaag attccattca ctttgaagaa
    39241 ttgacgttgg aaaatgtctc aaaaggacat ccttattttg aagctgaaga attaaaaatt
    39301 ggtccttttc tgattacttt tatggaaaca atccatccag tagtatgtta cgccatgcgt
    39361 atcgtagaag aaacaacggg gaaagtattc gtatttacag gtgattcagg ttatttggaa
    39421 agtttcgctg attttgcgaa agatgctgat ttgtttctag cagataccta tctttttgaa
    39481 ggaaatgaac atcatcatgc ccatttcact tcaaaagaag ctggagaact tgcgaaatca
    39541 gctaacgtaa agaaacttgt acttacacac ctacctcagt ttggtgattt agaacaattg
    39601 aaaaatgaag cgcaaaaggc agcaggcaaa gggattgata tagaacttgc tgcagttgac
    39661 aaagtgttta acatttagga ggaagaacat gatttttgta ccaaatgaaa accacgaccc
    39721 aagaatcaat ttagcaattg aacaatattt gctgcaagaa atgcctttag atgaacctat
    39781 tttgctcttt tatatcaatg aaccttcaat catcatcggc agaaaccaaa atacgcttga
    39841 agaaatcaat cgagattatg tggaagaaaa tggcattcat gttgtccgtc gcttaagtgg
    39901 aggcggagct gtctaccatg attttggaaa cctgaacttt agttttatca tgcctgatga
    39961 tggggattca ttccgtgact ttgcgaaagt aacacagcca atcatccaag cacttcatga
    40021 attgggtgtt gctggggcgg aattgaaagg ccgaaatgat ctagtcattg atggcatgaa
    40081 attttctggc aacgcgatgt atgctaccaa cggtcggatg tttgctcatg gaacaattat
    40141 gttcgactct gatatcaatg aagtagtcaa tgcattaaaa gtaaaaaaag acaaaatcga
    40201 atcaaaagga atcaaatcga tccgttctcg tgtaacgaat atcaaaccat ttcttccaga
    40261 agaaaagcaa aaaatgacaa cagaagaatt tcgtcaagaa atcttgttga aaattttcgg
    40321 cgtagagtca gtagaagaag taaaaacgta cgaattgact gatgaagatt ggaaaaaaat
    40381 caatcgaatc tctgaggaat attatcgaaa ttgggattgg aattacggga agtctccaga
    40441 tttcaatttc tctcgccaaa aacgtttttc tatcggttcg attgaagtcc atttgaatgt
    40501 ctcagaagga atgatcaaag aagcaaaaat ctttggcgat ttcttcggac taggagatat
    40561 ctctgacgtg gaaaaaaaat tggttggaca gaaatatgat aaagcatctc tatcaaaaat
    40621 agtcagccaa attgatgtga agaaatattt tggtgcgata gaaccagaag aattgcttac
    40681 cttactttat tgaaaataaa aaatagcgga atccacatat atggattccg ctatttttta
    40741 tacaggattc gggtaatttc gagagagttg aacagtgatc cgatcaatga aagtatcttt
    40801 ttcctgcgtt agtgttcctg tgtaacgatc cgctacgtct ttcatcatca ttaagtcaaa
    40861 acgttcctga tcatctaatt cttctgtgat gcctcgacta aataggtttg tatcgtaatg
    40921 tgcactatgt tcgcaacaaa tgacgaaatg ttcctcttgt tcgtgtatcg acaaataaat
    40981 ttttcgatac agtggatttt cgatggcatg agtttctcta aaggaatgct ctaaagcgtg
    41041 gatcaaaagt tgagccagat cgtcatcgtt gataggaagt tcttcgggaa gatctgcttg
    41101 gaaggttatc tgaatattcc gtttggcagc taacttctgg taacgcgcta agataagatt
    41161 tgtcacctgg tggttgcaaa aagaacacag catttcgaaa ttttttgctt cttctaatat
    41221 cttttccaca tagtttttag cttttgtttg gtccgtatgc attaaatctt gcagattctc
    41281 catctcttgg acaaattcca ggcgaagtgt atttacttct tggatatgct gtcgaagctg
    41341 ctcataatgt tgctccaaca aatcattttt gatttttaag aaatctactt gtctccgatc
    41401 tttgtcggta tttaagatgt gatcgattag attgtagctg ataataacga ttagaatgat
    41461 aatatataaa atcgtagacc aattgatcgt tgtttgatag atacctaatg ccgtttggat
    41521 gtaaatcaag caatggataa tggctaccaa gacgatccaa ggtgtacaag ctacataaaa
    41581 acggttattc ttatatgctt cgccaatgca tgcaagtgaa gtgactaaag tgcttataac
    41641 actagcaata ttagcaatcg gcattaattc aggaagttct gcaggagtaa aagttgcata
    41701 aagcagaacg ccgataaaaa tcaaaagttg gaacgtacaa aaaattccgt accatttttt
    41761 atagtaaaac attcggctcc aatagtagca gatgatgaaa gctgacgtta agataataaa
    41821 taaatgagat aaaaaagaat gaacgaatgg ttcaaaaaga ataccactta aaatatcttc
    41881 tgatacagct tcaaatccta atgccaaagc aaagcaactt aagagaataa gtgagtattc
    41941 aagacgtttt tgtttataca tcaagtagat cgtatagaaa aaggtcccta tagcgataaa
    42001 aacagcgatt atcatcgtca atacttgcgg cactgattgt gaataaataa aactaatcaa
    42061 tggtccagtt gttcctagat aaactttcgg tggcagtcca gcatagttct gataaggaga
    42121 tgagactgta agggtcaatt tttttccgat ataatttgct ggtaaatcta tcacagccaa
    42181 tgagagtccg ggattgcttt cttcctgata atctttccgt tggtataaaa tcttttcgcc
    42241 tagatataca gtaatccatt gatggtttcc tttgattagt aaatttgctt cgtccaacgg
    42301 tttttcaagt gtcgtttcca taatgaatgt ttcgtcttta tccacggtag gaatcgtacg
    42361 agtgtacttg ctgtcaa
//
LOCUS       DAFTHM010000012        40749 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFTHM010000012 DAFTHM010000000
VERSION     DAFTHM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.012"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..371
                     /locus_tag="L7C88_000685"
     CDS             <1..371
                     /locus_tag="L7C88_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9557540.1"
                     /translation="FVVEQQCPYQEVDDIDGEAWHTFFQDTDGKILAYTRVYEEAESI
                     HFGRVLVHQDNRKDGLGRKIVQETINMIQKNFPEKPIVIGAQEYLQAFYESFGFKAIS
                     DVYLEDDIPHIDMKKEQVAS"
     gene            complement(430..891)
                     /gene="mscL"
                     /locus_tag="L7C88_000686"
     CDS             complement(430..891)
                     /gene="mscL"
                     /locus_tag="L7C88_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBP9557541.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            1143..2411
                     /locus_tag="L7C88_000687"
     CDS             1143..2411
                     /locus_tag="L7C88_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBP9557542.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            2404..3690
                     /locus_tag="L7C88_000688"
     CDS             2404..3690
                     /locus_tag="L7C88_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBP9557543.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            4429..5352
                     /locus_tag="L7C88_000689"
     CDS             4429..5352
                     /locus_tag="L7C88_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557544.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            5561..6139
                     /gene="pgsA"
                     /locus_tag="L7C88_000690"
     CDS             5561..6139
                     /gene="pgsA"
                     /locus_tag="L7C88_000690"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBP9557545.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            6379..7620
                     /locus_tag="L7C88_000691"
     CDS             6379..7620
                     /locus_tag="L7C88_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBP9557546.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            7729..8778
                     /gene="recA"
                     /locus_tag="L7C88_000692"
     CDS             7729..8778
                     /gene="recA"
                     /locus_tag="L7C88_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBP9557547.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            9189..10745
                     /gene="rny"
                     /locus_tag="L7C88_000693"
     CDS             9189..10745
                     /gene="rny"
                     /locus_tag="L7C88_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBP9557548.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(10824..11630)
                     /gene="proC"
                     /locus_tag="L7C88_000694"
     CDS             complement(10824..11630)
                     /gene="proC"
                     /locus_tag="L7C88_000694"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBP9557549.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            11771..14344
                     /gene="mprF"
                     /locus_tag="L7C88_000695"
     CDS             11771..14344
                     /gene="mprF"
                     /locus_tag="L7C88_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBP9557550.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            14486..15349
                     /locus_tag="L7C88_000696"
     CDS             14486..15349
                     /locus_tag="L7C88_000696"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBP9557551.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            15594..16532
                     /locus_tag="L7C88_000697"
     CDS             15594..16532
                     /locus_tag="L7C88_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBP9557552.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            16555..17235
                     /locus_tag="L7C88_000698"
     CDS             16555..17235
                     /locus_tag="L7C88_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBP9557553.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            17208..18032
                     /locus_tag="L7C88_000699"
     CDS             17208..18032
                     /locus_tag="L7C88_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBP9557554.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            18199..19017
                     /gene="purR"
                     /locus_tag="L7C88_000700"
     CDS             18199..19017
                     /gene="purR"
                     /locus_tag="L7C88_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBP9557555.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            19520..20893
                     /gene="glmU"
                     /locus_tag="L7C88_000701"
     CDS             19520..20893
                     /gene="glmU"
                     /locus_tag="L7C88_000701"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBP9557556.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            20987..21958
                     /locus_tag="L7C88_000702"
     CDS             20987..21958
                     /locus_tag="L7C88_000702"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBP9557557.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     regulatory      21964..22066
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22132..22701
                     /gene="thiT"
                     /locus_tag="L7C88_000703"
     CDS             22132..22701
                     /gene="thiT"
                     /locus_tag="L7C88_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBP9557558.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     gene            complement(22782..23555)
                     /locus_tag="L7C88_000704"
     CDS             complement(22782..23555)
                     /locus_tag="L7C88_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557559.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            23822..25522
                     /locus_tag="L7C88_000705"
     CDS             23822..25522
                     /locus_tag="L7C88_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBP9557560.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            25492..25710
                     /locus_tag="L7C88_000706"
     CDS             25492..25710
                     /locus_tag="L7C88_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBP9557561.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            25730..26620
                     /locus_tag="L7C88_000707"
     CDS             25730..26620
                     /locus_tag="L7C88_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBP9557562.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            26638..26922
                     /locus_tag="L7C88_000708"
     CDS             26638..26922
                     /locus_tag="L7C88_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557563.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            27409..28023
                     /gene="gmk"
                     /locus_tag="L7C88_000709"
     CDS             27409..28023
                     /gene="gmk"
                     /locus_tag="L7C88_000709"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBP9557564.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            28028..28333
                     /locus_tag="L7C88_000710"
     CDS             28028..28333
                     /locus_tag="L7C88_000710"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBP9557565.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            28586..30994
                     /gene="priA"
                     /locus_tag="L7C88_000711"
     CDS             28586..30994
                     /gene="priA"
                     /locus_tag="L7C88_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBP9557566.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            31009..31500
                     /gene="def"
                     /locus_tag="L7C88_000712"
     CDS             31009..31500
                     /gene="def"
                     /locus_tag="L7C88_000712"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBP9557567.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            31493..32431
                     /locus_tag="L7C88_000713"
     CDS             31493..32431
                     /locus_tag="L7C88_000713"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBP9557568.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            32431..33789
                     /gene="rsmB"
                     /locus_tag="L7C88_000714"
     CDS             32431..33789
                     /gene="rsmB"
                     /locus_tag="L7C88_000714"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBP9557569.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            33802..34542
                     /locus_tag="L7C88_000715"
     CDS             33802..34542
                     /locus_tag="L7C88_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBP9557570.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            34539..36608
                     /gene="pknB"
                     /locus_tag="L7C88_000716"
     CDS             34539..36608
                     /gene="pknB"
                     /locus_tag="L7C88_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBP9557571.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            36773..37672
                     /gene="rsgA"
                     /locus_tag="L7C88_000717"
     CDS             36773..37672
                     /gene="rsgA"
                     /locus_tag="L7C88_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBP9557572.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            37685..38335
                     /locus_tag="L7C88_000718"
     CDS             37685..38335
                     /locus_tag="L7C88_000718"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBP9557573.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            38336..38974
                     /locus_tag="L7C88_000719"
     CDS             38336..38974
                     /locus_tag="L7C88_000719"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBP9557574.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            39129..39983
                     /gene="mreC"
                     /locus_tag="L7C88_000720"
     CDS             39129..39983
                     /gene="mreC"
                     /locus_tag="L7C88_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBP9557575.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            39987..40496
                     /gene="mreD"
                     /locus_tag="L7C88_000721"
     CDS             39987..40496
                     /gene="mreD"
                     /locus_tag="L7C88_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBP9557576.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
BASE COUNT        13368 a         7208 c         8836 g        11337 t
ORIGIN      
        1 tttttgttgt ggaacaacag tgtccttatc aagaagttga tgacattgat ggagaagctt
       61 ggcatacgtt ttttcaagat actgatggga agatccttgc ctacacgcga gtatatgaag
      121 aagcggagag tatccatttt ggacgtgtcc ttgttcatca ggacaaccgt aaagatggtt
      181 taggaagaaa gattgttcaa gaaacgatta acatgatcca gaaaaatttt ccagaaaaac
      241 caatcgtgat cggcgcacaa gaatacctac aagcttttta tgagtcgttt ggattcaagg
      301 caatctcaga tgtgtatttg gaagatgata ttccacatat cgacatgaaa aaggaacaag
      361 tagcaagtta agaatctaaa aaaagaaagc cgacactgaa aatcggcttt ctttttttta
      421 gattctttat tatttagaag tatcggaaag atttgtttgc tctactggat gtgtattgtc
      481 ttctgccact tgtttggcaa gaagatcgcg tatgtcacta agataatctt ctgcagtagg
      541 agtttcttcc acttccactt gctcttcttt ggagcgtaaa ttcttcgcac ggtttgccgc
      601 tttgacaact aagaataaga caaaaccagt gatcagaaat gtaatgatag cactaataac
      661 gttaccaaac gcaaatgtga cgccttttgt cggcgaccag tcaagaattg aaagtgctcc
      721 ttctaaatca gaagtacctg tgatcattgc gacaaaccaa cctattagtg gtgtgatcaa
      781 gccttgcacc acttggttta cgatgcttgt aaacgcacta ccaataacaa cgccgacagc
      841 aagatccaag acatctccac gcatgatgaa ctctttgaat tctttgatca tgaatgaccc
      901 tcccttcttt tatttgtctt tagtatatcg aaaaataaaa aataaaaaaa caatatacgc
      961 ttttagccgt ctgtttcttt tgataaaaaa catctatgct atactataaa gtgtaacatc
     1021 atttagaaaa aacggcgaat tgcctgaact tataaatttc aagcagagga ataagtaaaa
     1081 aaggcaggtt gacccattaa aagagtaagc gggcaatcaa ctgtgaaaag gagcatataa
     1141 atatggtgta tcaattggca gaaggcgtga atcttcatgt cttaccaaca aaacaataca
     1201 aaacgatccg gatttttatc cgttttactg cgcgtctgca acaagaagtc atcacgaaac
     1261 gttcacttct cagcagcatg ttggaaacaa atagtttgaa ttattcggat cagacaaagt
     1321 taagtgcgca acttgcagag ctttatggcg caagctttgg attatcagtt agaaaaaaag
     1381 gaaatttaca ttggctaaac gcagggatca gttttgtgaa tggtgaatat gtcaatgatc
     1441 caaacctttt ttctcaagcg gtagattttt taaaagaggt tttattttat ccaaatatta
     1501 aaaatcatca gtttgatcag ttgacgtttg acttggaaaa gaacaatctg cgtctatatt
     1561 tggaaagttt gaaggaagat aaacaaactt ttgcttccta tgccttgcaa gaactttatt
     1621 ttgaaaacag cccggaacaa aagatcccag ggttgggcgt agtcgaagat ttggacaaga
     1681 tcactgctag ttcgctagcg tcctactatc aagaaatgat ggcaaatgat caaatcgaca
     1741 tttttgttgt cggcgatgtt gatccggaca aagcagctga agcagttggg caattaccat
     1801 ttgagtcgcg ggaaacagtt tatccagatc tgttttatac ccaacctcaa gtgaatatcg
     1861 tgaaggaacg acaagtacgt gagccaatcg ttcaagcaaa gctgaaccta gcttatcaga
     1921 caaatgtgta ttacgatgaa ccagaacgtt ttgcgctaat ggtctttaac ggtttatttg
     1981 gcggttttcc tcactctaaa cttttcatga atgtcagaga gaaagaaagt ctagcttatt
     2041 atgcctctag tagcgtggat acgttccgag gattcatgag tgtccaaacc ggtatcgatg
     2101 aaaagaaccg aaatcaagta cttcatctga ttcacgagca attagaaagt ttgcgaaatg
     2161 gtgaaataac agagttggaa ctgtctcaga caaaagcaat gctgagaaac caatatctgc
     2221 tttctctaga ctctccgcaa gcggcaatcg aagcttcttt tttggacagc tggctgccgg
     2281 aaacaaaatt atctgatgaa gaatggttga aacgtatgga gagcgtaacg atcaaagaga
     2341 tacaacaagt agctgagcaa atcgaattgc aggcaatctt ctttttagca ggaggaaatg
     2401 caaatgaata aaacagaata tgagcaaatc aatgaaacac tttatcatga agtactgcca
     2461 aacggtttga ccgtgtattt gttgcctaaa aatgactatc acaagacata tggtttgttc
     2521 agtacgaatt atggttcgat cgataacgaa tttattccct atggtgaaaa agaaaaggtg
     2581 aaagttccag atggaattgc ccatttttta gaacataagt tgtttgaaaa agaagatggt
     2641 gatgtctttc aattatttgg gaaacaagga gcttccgcca atgctttcac aagttttacg
     2701 aaaaccagct atctgttttc tacgacggat caggtagaaa agaatctgac gactctgatc
     2761 gattttgtac aagcacctta cttcacagaa gaaactgtaa acaaggaaaa aggaatcatc
     2821 ggtcaggaaa tccaaatgta tgaagacgac cctaactggc ggatgttttt tggcatacta
     2881 aataacttgt atcctacaca cccattgcat atcgatattg cgggcacggt tgaaagtatc
     2941 gacaaaatca cagctcaaga cttgtatacg tgctatcgga cgttttatca gccaagcaat
     3001 atggttttat ttgtagttgg taagatggag cctgagaaat tgatgaaact tattcgggaa
     3061 aaccaagaag caaaaaattt ccctccaaag caagaaattg tacgttattt ccctgaaaac
     3121 acaaaagaaa tcatcaaaca aagtgcattg gaagcagcca ttacacgaga taaatttgta
     3181 cttggtatta aaggattaga cacattgccg caagaaggaa cagaactgtt acgctataaa
     3241 acagcaatca atctgttgtt ccaaatgatt ttaggcaata cttctcgaaa ctatctagcg
     3301 atgtacaatc aaggaattat cgatgacagc tttggttttg aattcagctt ggatcgtgaa
     3361 tttcactttg cggacttcag cggagatacg gacgaaccag agaaagcagc agaaaaagtc
     3421 aaagaaatca ttcttggatt cgctgatgat ccggaagtgt cagaaacaaa tctcgatttg
     3481 ctgaagaaga aaatgcttgg acaatatttc caatcattaa attcgatcga atatattgcc
     3541 aatcaattta cgcaaagttt atttggcgat cgaactttat ttgatcttcc tgaaatcatc
     3601 gattcgatcc aaatgaaaga cgtactggca gctggggaag catttataag tgaagaggcc
     3661 ttcagcgagt tttacatgag accaaaataa accagtattt tatgaggaaa agtcttaaat
     3721 ttcgttttag acttgtagta ggaacctcct ccaaaatcag cttttatggt attcttagtt
     3781 gtgttggaaa aattagtgag aaaataaaac aaatcatgct ctcttttaat caacttatat
     3841 taaaataaaa tcaaacgaag taatcaaaga ggttgtgaca gaagtggtca gcttcaagaa
     3901 ataagaagga atttacgaaa attgcttctc aaatttttgt gatatttcgg cttattgccg
     3961 aagaagctac ttctggaaca ccgtgtacca agaggttgtg aaaaagctgc cctgcatcaa
     4021 gtaataagaa cagccaagta aaaacagctt cttaatgttt ttaacttggt tggacttatt
     4081 accgcagatg caagcttttg aacaccgttt aaggaagagg ttgtgaaatc agcgttttga
     4141 cctgagtatt agagaaacat acggaaaaat atctccttat attttgccgg tttttgagct
     4201 aataccgagg aacagctgat tgaacaccgt ttaagaaaga ggtcgtgagc ctgccgttta
     4261 actccgagtc acaaggaaca agttcaaaaa acagcttctt atatttattg gatattgtga
     4321 cttgtgaccg aggagttggc aggagaacaa tgtttattcg gaaaaaagga gctgtgacat
     4381 gacttttgtc acagcaccca aacataacgt ctttcgttgc aacagcagat gcttcggaga
     4441 atcaaacaga ctggagaaga tgaacgagtg gcttttgaaa ccatcggaga aaaattacgg
     4501 caagcacgcc tgaataaaaa aatatcttta gatgaattac agcagattac aaaaattcaa
     4561 aaacgttatt tggaagcaat cgacaatgat gattttgacc aattgcctgg taaattttac
     4621 gtgcgggcat ttattcggca atacgctgaa gctgtaggag aagatggaga ccatttagtc
     4681 gatgtttttg atgggaaaag caaattgaca ggatcggtcc ctgaacgtcc gcagcctgaa
     4741 acagtaagta cttctagaaa agcaatgcat caggaagaat cgcatccaag tcgcttttgg
     4801 acaagtcttc ctgtcatttt attaggattg gttgctttgg cgattgtcgt tgtcgtgggc
     4861 tatatgactt ggcaagatcg tcaagctgat ccaataatcg gagacacagc ttcttcgctt
     4921 aaagtagaag gatcagtcga ggagtcctct tcctcagagc aaagcacgca gaccaaagag
     4981 tcttctacag tagaatcaac aacaaaatca agtgaagaaa agaaaatggc aatagctaca
     5041 ggagaagatt ctggcagtgc catcgcagta aatatcacag acgctaccaa gcctgtaacc
     5101 cttgaattta ctgctgtcaa tcgtgtatgg ttaggtgtgc tagtagacaa tgcctatgtt
     5161 tatcaaggga cactggcagc aaatgaaaca cagagtaccg tgttaccgga aacagcaaca
     5221 aatgcgacca tcacgattgg tgcagcaagc aatgcaacga tcaaagcgaa tggagaatcc
     5281 gtaccagtta atccagggga aaacaatcag agtccaaaaa atgtgaacct tactcttcaa
     5341 tacgcagaat gatcgtataa attagtttac gcatctgttt acttgtaggt ataaaaaaga
     5401 aggatcgtga caaatctgtg tcgcggtcct tcttcgttaa ttcaaaaaga tcaatttcaa
     5461 taaaaatact cctttgaata aattcatttg gaaaagtaaa taatatcggt ggaaacttcg
     5521 ctgatagtca cgtagaatag ggaagaaagg agtcgatagt gtgaatttac caaataaatt
     5581 aactgtactt agaatttgta tgatcccgat tttcattttg gttgtaggtt tacctttaga
     5641 ttggggacaa tttaacgtag gagacaccac actggctgtc acacagctag taggtgcagt
     5701 tatttttgct ttagctagta tcacagactg gttagatgga aaaattgccc gtgcgcgagg
     5761 ccttgtcact aattttggca agtttgcgga cccgttggca gataaaatgc tagttatgac
     5821 tgcttttatc atgttggttg accaaggaaa ggcccctggt tgggtagtag cgatcattgt
     5881 ctgtcgtgaa ttagccgtca caggcttgcg tttactactt gtcgaacatg gagaagtcat
     5941 ggctgcagct tggccgggaa aagtcaagac ggctacacaa atggttgcta ttatcttgct
     6001 gtttatcaat aatatcccat tcagcctgat cggtattcca gtagatcaaa tcatgcttta
     6061 tgcttgtctg atctttacta tctattcagg tgtggattac ttcatcaaaa acagcggtgt
     6121 gttcaaagga tcaatgtaag tatcgtttag tggagaggtt gtgagcctgc cgtctaactc
     6181 tgagtcacaa gggataattt caaaaaacag cttttcatgt tttatgtata ttgtgactta
     6241 tgaccgaggt tttggcagga gaacactgtt tatttggaac aaggagctgt gacaagattt
     6301 ttgtcacagc tccttgccct ctttttaaat aaaaaaatat aaaaatacag cgtatactat
     6361 ataagggagc gggaagtaat gaaagcagaa ataatagctg tcggaacaga acttttacta
     6421 ggacaagtcg tgaatacgaa tgccactttc ttgtcagaac agctagctga tctaggtatc
     6481 gaagtttatt atcaaacagt tgtaggagat aatcagcagc gtttagaaga gttgattgct
     6541 ctagctgaaa caagaagtga actcatactc ttatgtggcg gattaggacc gacagaagat
     6601 gacctgacaa aagaagcaac tgcggctcac ctcggtaagt ctctcataca aaatacggaa
     6661 ggatacaaaa aattattggc atattttgaa acaacccatc gaaaaatgac caaaaacaat
     6721 ctgcaacagt cccagattat cgaaggcggg gttcctctac caaatcgtac agggcttgct
     6781 ttagggactt tttatcaaac agatacacat gcgtatatcc ttcttcccgg tccgcctaat
     6841 gagttgaaac caatgtttgt ggaacaagta cgtcctttac tagaggaacg ttttccttct
     6901 gaagaaaaac taatttctaa agttttgcgc ttttatggga ttggtgaatc gcgactggtc
     6961 actgagctaa aagatctgat tgagacacag atcaatccaa cgatcgcacc atatgccaaa
     7021 ccaaatgaag tgacattacg actgacagtg aaaacaaatg atgttcaggc agggaatcaa
     7081 gctcttttag cattagaaga aaaaatccaa gaacgagtag gggaatattt ttatggatac
     7141 ggcgatgata attcgctagc aaaagtcgta gtggaactac tgaaagaaaa caagcagact
     7201 gtaacagcag cggaaagttt gacagccggc gccttccaag ccgcattagg cgacattgct
     7261 ggtgtatctg aagtatttcc aggcggattc gttacctact cgctccaaac aaaagctggt
     7321 tttctggaga ttgatccgga gctattagca gaatatggaa cagtcagcaa agaatgtgtg
     7381 gagcagatgg ccattcaagc acgtgagata gcaagaacag attacagtgt agctttcacc
     7441 ggagtggctg gaccggacac gttagaaggt caatctgcag gaacagtatg gatcgctatt
     7501 tcatctaaag acggcgtggt ttcggaaaaa tatcactttg ccagagatcg tgctgctatc
     7561 agatataatg cggttatgca aggatttgat cttttgagaa aacagctttt aagaaaatga
     7621 taaatgcgaa tatttgttcg gttttttctt gctttttttc actaaaaaag atatgataag
     7681 gataatgaaa tgttgctctg atttgtaaat ataaggagga ttatcgtatt ggcagatgat
     7741 cgtaaagcag ccttagatgc tgcactgaaa aaaattgaaa agagctatgg taaaggctct
     7801 attatgaaat tgggcgaaaa aatcgaccaa caaatctcta caattccaag tggctctctt
     7861 gcgttagatg tcgctttagg tgtcggcggt tacccccgtg gacgtatcat cgaagtatat
     7921 ggacctgaaa gttcaggtaa aacaacagtt gcactacacg ctattgcaga agtacaaaaa
     7981 aatggcggaa cggccgcttt cattgatgct gagcatgcgt tagatccgca atatgcacaa
     8041 aaattaggtg tgaatatcga tgaactactt ctttcacagc ctgacacagg agaacaaggt
     8101 ctagagatcg ctgatgcttt agtatcaagt ggggctgtag atatcgtagt agtcgattca
     8161 gttgctgctt tagttccacg agcagaaatc gacggcgaaa tgggtgactc acatgtcggg
     8221 ttacaagcac gtttgatgtc tcaagcattg cgtaaactct ctggttcgat caacaaaaca
     8281 aaaacaatcg ctattttcat caaccaaatc cgtgaaaaag taggcgtgat gtttgggaat
     8341 ccagaaatca ctcctggagg acgcgcattg aaattctacg caacgatccg tttggaagta
     8401 cgtcgtgcag aacaattgaa acaaggtaca gatattgttg gtaaccgtac aaagatcaaa
     8461 gtcgtaaaaa acaaagtagc acctcctttc aaaatcgctg aagtagatgt catgtatggt
     8521 ttagggatct cacaagaagg agaacttcta gacatggcag tagaaaaaga cattgttgat
     8581 aaaagcggtg cttggtattc ttataaagaa gatcggattg gtcaaggacg ggaaaacgct
     8641 aaaatctata tggctaatca tcctgaaatg atggcagaag tttctgctct agttagagca
     8701 gcttatggta ttggtgaaga agtcgctgtc ccagaagatg aaaaaggaca agaagaattg
     8761 cctttagtag aagaataaaa attatgataa acaaaaacgg ctggtctgaa gagtaggtac
     8821 tctccttgac ctgccgtttt tttattgaat aaagaaatcg tgagttattt aattatacga
     8881 gtgggtacat aaaataaaaa tatctgttca tctacaaaga ataatttaat agaaaagttt
     8941 ctcaatttaa aggtttacct atatgaaact agtgtcattt attttaaaaa ccatcgttta
     9001 atgaataagt agaaagccgt ttctttgttt atttaaagtt gacactacgg ggtacaaaca
     9061 ttagaataaa gttgtgcatg ttttttgtac acatatatgc gaagatgcat attgacgagt
     9121 ttagaataat ttatcataga agctgtatag atgataaaaa tgaaaaagat agtatggagg
     9181 tggattttat ggtattcaac attctcctcg ctatcatcgg tttaattgtc ggtcttggtt
     9241 tagggtttat ggtcgcaaag tcacgtcacg agaaagaaat agctggtgca caatcatcag
     9301 ctgctggaat catcgatagt gcaaaaaaag aagcagaaac tctaaaaaaa gaagcattgt
     9361 tagaagctaa ggaagaaaat cagaaatacc gttctgaagt tgaaagtgag ctgagagaaa
     9421 gtaagttaga attaaaatct caagagaatc gtttgattca acgcgaacaa acgctgaatc
     9481 gtaaagatga ctcgttagaa aaacgcgaga actcacttga aagtaaagaa gaagcactta
     9541 gttcaaaaca gcaattaatt gaagagcgag aaaaagacgt tgaaaaaatg attgaagatc
     9601 aacaaaaaga actagaaaaa attgctggtt tatcaaaaga ggacgcacga gatgtcatca
     9661 tgaaatcgac tgaagaagag ctgaatcatg agttaactct aatggtaaaa gaatctgaac
     9721 agcgtgccaa agaagaagca gatcgcaaag cgaaaaactt attatcatta gcgattcaac
     9781 gctgcgcagc agatcaagtt tcagaaacga ctgtttcagt cgttaccctt ccgaatgatg
     9841 aaatgaaagg tcgtatcatt ggacgagaag gtcgtaatat tcgaacgctt gagacgctga
     9901 ctggtatcga tttaatcatc gatgatacac cggaagcagt tgttctttcc ggattcgatc
     9961 caatccgaag agaaatcgca cggatgacct tggaaaaact gatacaagat ggacgaatcc
    10021 atccagcgcg tatcgaagaa atggtcgaga aatctcgtaa agaaatggat gaacgtattc
    10081 gcgaatacgg ggaagaggca gcgtttgaag tcggtgctca tacacttcat ccagatctaa
    10141 tcaagatcat cggacgtctg cgattcagaa ctagttatgg acaaaacgtc ttgaagcatt
    10201 cggtcgaggt tgcaaaatta gctggtatct tagcagcaga gcttggcgaa gatatccaat
    10261 tagcaaaacg tgccgggttg ctccatgata ttgggaaagc acttgaccat gagattgaag
    10321 gatctcacgt tgagatcggt gcggaattag ctgccaagta caaagaaaac ccagtagtaa
    10381 tcaacgcgat cgcttctcat catggagatg tggaagctac ttctgttatc tctgtccttg
    10441 tagctgcagc agatgcgctc tcagcagcaa gacctggtgc gcgaagtgaa tcattagaaa
    10501 actacatccg tcgtttaaga agtctggaaa atatttcgaa cagcttcgcc ggtgtagaat
    10561 caagttacgc agttcaagct ggacgcgaag ttcgggtaat ggtcaagcca gaagaaatct
    10621 cggatttaga cgctgttcgt ttagtacgtg atattcgtaa acgaatcgaa gaagaactgg
    10681 attatcctgg acacatcaaa gtaatcgtta ttcgggaaac tcgtgcaact gattatgcta
    10741 aataataaaa aatacaaaag aagagccgcg gcaaaagcca cagctcttct ttttttgtaa
    10801 ggcacgaaaa aacattgcta tcattatttt ttattcaaca tctcaagatc tttctcgatc
    10861 gtcgtattga ttcctttgat gattgctggg atgaatcctg cttcttctaa ggcaactaca
    10921 cctgcaacag ttgtaccgcc aggagaagaa acttggtcta caagttccca tggattttta
    10981 tcacttgaaa ggaatttttg acaagaaccc ataattgctt ttgcagcaat ctcagtggct
    11041 gtctgtttgg acaaaccatt cagtacacca gtccgtccca tcgcatcgat cagcatgtaa
    11101 acgaatgcgg gtgagctgcc agcaaggcca atgaatgtac tgaaatctga ttctgctaaa
    11161 ggatagacgc tgccgattgc ttcaaaaatc atcgtagctt gctgaagctg ttcctccgtg
    11221 gcagcttcat ttttgcaaat cgcagaaacg cctgctccta cgctgacatt gacattcggc
    11281 atcacacgta cgatggaggc ctgaggatct tcaagcgctg tttctaaatc tattaatgat
    11341 tttcctgaag caatagaaat gaataagact ttctggctat attctcttag ttcttccaat
    11401 actttttcaa tgatttttgg tttcacggct aaaagaacga tatctgattg tgatgcaact
    11461 tcctgattac ttttgcatgc atggacgcca gtttcagcag caaatttttg tgcattttca
    11521 aaatgtccac tggaaacgaa cacctcttct ttcgagactg ttcctttttt taataaacca
    11581 tcaataatag cttgtgccat attccctgtg ccgataaatc ctactttcat gttatcctct
    11641 cctttagcat taggatatct ttctttttct atcatcgcaa gcaaagaaca ggtctaaagt
    11701 ggaaaaatta aaataaataa gataacattg gggtatgaca caaaagtata caagttagga
    11761 atgggaaaat gtgaaaaata aacgatactt gatgctgcaa tggataaagg aacatagtct
    11821 gattttaaaa ctgatttttt tcggctccgt gttagtcttt gtggcaaatc aagtcgcaaa
    11881 tattgctaat ggcatgagtt ggcaagatat ttggcaaagg atgggacaac aaagccgcat
    11941 gacgatcctg ctcatgattc tggctggact gctgggtgtc actccgatgt tgttgtatga
    12001 ttgggtgacg atcagagtct tagaaaaaca aggaaaacca aaaatggaaa gaaaagagtt
    12061 tcttcttgct gcgtgggtaa caaacacgat caacaatctc gccggttttg gtggtgtggt
    12121 aggagcaagt ctgcgggcta gtttttatgg aaagcagaca aatagaaaaa tggttttagc
    12181 cactgtatca aaagtcgcac tatttatgct gactggtttg tctgtatggt cgtttcttac
    12241 atttattgat gtctttttta ttcagtcaga aagtattttt cgaagctatt ggatctggct
    12301 tttcggcggt agttttttag caccagtcat tttctttttt gcttatctaa agagaaagac
    12361 attgttcttc gagttttatc caaaaggctt gcttggtctg ctactggcat cctttggaca
    12421 atggacggga gcccttgcgg tatttttgat catcggcaag ttgatgagaa tagatatttc
    12481 gatgctttcg atctatccta tgttcatgat tgctacattg ataggaatgc tgacgatggt
    12541 cccaggtgga atggggactt ttgacgtttt gatgatctta ggaatgagtc aattgtctgt
    12601 tcggcaagat gtagcagtag tttggctatt atattatcgg ttgttttatt atgttctacc
    12661 ttttatgacg ggacttctat tgttcatcac acatacagga gtcaaaatca atcgattttt
    12721 agataacatt ccgcgactgt ttttccaaaa ggttgcgcat atcgtgctcg taagtgctgt
    12781 ctattttgcg gggatcatga tggtacttct atcaacaatc actaatctgt ctgcaatcag
    12841 tcggctattt caagtattat tgccgttctc attcaatttt ttagatcaga cagtgaatct
    12901 attggttggc tttttattac tcggccttgc tagagcactt tcagtaaaag tcaaaaaggc
    12961 atttctgcct acgattgctt tactatcttt tggtatttta aatacaatca cacgtacgtt
    13021 atcttggcag ttgatattgg tatatgtctt gattctgtta gctgtgtggt tatccagaaa
    13081 agaattttat cgaacaaaat tcgtttattc ttggggagct ataatctttg atgctagctt
    13141 gttcggcttt ttgtttatcg tttacgcaat tgcaggctat cacagcggac gctttttagt
    13201 cggtcgaata acaggaaatc attttatttt gtttccttca gatgatgtgt ggttctcagg
    13261 gcttattggt ttgggcatct cattgctagc tttagtggcg ctttatcaat atttagctga
    13321 agatactacg aagcttggca gtgagtacga aaaagaccgt tttgaccgtt tattggaaac
    13381 atacggaggc acagctacaa gccatcagct tcgcttgtca ggttacagtt atttttatta
    13441 ccaagaagac gaccaagatc aagtcgtttt tggttatcag atcaaaggaa acaaatgctt
    13501 tgttttagga gatccagttg gcaatcctaa aatgatgcgg gcagcaacga atcagtttat
    13561 gaaacaagca gattgtttag gctatcagct tgcgttttat aagatatcag aaagctacgt
    13621 agtgatgctt catgaattgg gttttcactt cacgaaagta ggtgaagcag ggattgttga
    13681 tctagcaaca gaagacttgt ctcggctgag tcagcaactt gaatatcaac gtttgatgaa
    13741 agaaggatac cattttactt ggtacgatca actgccggaa gaattacatc aagctgtaaa
    13801 tgaagtttca caaaaatggc ttcaaggtgc acgagaaaaa tacttctctg tgggacgatt
    13861 tgataaatca tatgtattat ctagcggtgt cggtattgtc cgtaaagatc aaaaagtcgt
    13921 tggcttcatc accgctcagc cgatgacgaa gaagcaggcg ggatatgatt tgttgcgggt
    13981 cttacctaaa gaatctgagg aattagctga ctatctgtta gccaatctgt ttattgtata
    14041 cgagaaaatg ggctactcgg aagccaatct aggcttagct ccattagcta atgttggaga
    14101 aacagatttt tctttctttc aagaaaaagt catgcatatc gtatataatt atggtaattt
    14161 tttctattcc ttccagtctg cttatgaaaa gaaattaaaa tatgtcgatc attgggaagg
    14221 acgttatttt gcttatagga aaggaagtaa tttcggattt gctaccatgc agctactcag
    14281 tctgatagga aaagaaaaag gaaatgttcc gagtttggca gaagaagtgc tcacagaatt
    14341 ataagaatca ctagaacttg tttggattat gaagagaaaa ttctgtgaaa gctgttgaaa
    14401 cgatgacaaa atcaaccact aggcagacat aagctatact tttatttttc cctatgatag
    14461 aatacttgcg acttagactt ttcgaatggg tgagaggatg gaattgattg aaaaagcgcc
    14521 agccaagata aatttaggac tggatgtatt atatagacgg caagatgggt atcatgagtt
    14581 ggaaatggtg atgtcgagcg tagacttggc agatcatcta ttttttgaag aaataacaga
    14641 agacaaaatc attgtagaaa caaataaagc atttttaccg gtagatgaac ggaacaatgt
    14701 ttatcaagct gctttattgc taaaaaataa atacaatatc aaaaccggtg tcaagatctt
    14761 tgttaagaag aatattccag tagcagctgg attaggcgga ggaagtacag actgtgcagc
    14821 tgctctaaga gggatcaacc aattatggaa tctgggctgt tcgttagaag aactggcaga
    14881 aatcggtttg gaagtcggta cagatgttcc ttactgtgtc tacggaagta cggcatttgt
    14941 cggtggcaaa ggggaagaaa tccaagtatt accttctatg ccacagtgct gggttgtgtt
    15001 ggtcaaacca agaatgagtg tctctacacg tacagtgttt agagaagtag atacgcaagc
    15061 catccaacat caagacatcc acggacttgc tgaagccatc cgagagcaag attatcagca
    15121 gatgatcaaa aaaatgggaa acagtttaga agatataacg ggaaagcggc atccagtcat
    15181 ccatcaaatc aaagagcgta tgatcaagta cggagcagat gctgcattga tgagtggaag
    15241 cggaccaacc gtttttgcct tgtgtcaaca ttattcaaga gcgcagagag tatataatgg
    15301 gttaaaaggt ttttgtgagg aagtttattt agtacgaacc ctgcaataaa atataagaag
    15361 taaaataggt gatgaaaaac tgaggaatcc taaaatggta ttcttcagtt ttttattgta
    15421 gtgaaatggc tagatatgag cagcaactca tccattttac gatttaatca agaatataca
    15481 tgcttaaatc agaaattgat ggatttctat tgactgtgtt tttttatttt gatacattag
    15541 ttcacgttaa taaatcgtaa aattccgatt tgttcattga aaggagcata taaatgaaaa
    15601 aatatctttt gacagctacg gtaatgatag gtgctttact gtttgcagca tgtggaaata
    15661 cgaacaagga agcagacaaa aaagaggatt tgacgatcgt tacgactttt tatccgatgt
    15721 atgattttac aaaagagatc gtaggggatg aaggaaacgt gaaacttttg atccctgctg
    15781 gaacggagcc gcatgatttc gaaccaagtg caaaagaaag agcagaaatt tccgatgcag
    15841 atgttttcgt gtataatagt tcagacatgg aattttttgt ggattcgtta aaggattcag
    15901 tggatagcaa acagaccttg atgatcgaag cagctaaagg aatcgaccgt ttagaatcgc
    15961 aagaagcaga cgaacatgaa gaatcagaag aagggcatgg tcattcacat gaatacgatc
    16021 cacatgtttg gctcgatccg gtattagcta taaaagaagt cagaacgatt gctgaagaat
    16081 taggcgaaaa atatccagat aaaaaggaaa cttttacgaa gaatgccgat gcttatatca
    16141 aaaagcttga agcactggat caaaaatact ccgatgagct aaaagatgca acaaaccgca
    16201 catttgtcac tcagcatgct gcttttgctt atttagcgaa tcaatacgac ttaaaacaag
    16261 tagcgatttc gggcgtttca ccagatcagg aacccacacc aagtcgctta gctgagctaa
    16321 aagaatttgt gaagaaaaac aacatcaaag tgatttattt tgaagaaaat gcctcttcga
    16381 aggtagctga gacattgtcg aatgaaacag gagtgaagct agaagtgttg aatcctttag
    16441 aaagcttgac taatgaacaa atcaaagcag gcgaaaatta tatttctgtc atggaaaaaa
    16501 atctgaaagc tttaaaagaa agtatcaatt aagttttaga atggaggttg taaggtgcgt
    16561 tatatcgaaa tatctgattt gaccttttac tatgatgatg aacctgtact agaagatgtc
    16621 tcttatcatg tagatgcggg tgaatttgtc attttaactg gagaaaatgg agcagccaag
    16681 tcaaccttgg tgaaagcatc gttaggatta ctgaaacctt caaaaggaat gataaagatt
    16741 gctgagaaaa atcaagaagg aaaaaaatta agtatcggtt atattcctca acaagttgca
    16801 tctttcaatg caggttttcc tagtacggtg atcgaattag tccgttcagg aagatatcca
    16861 agaggccgct ggttcaagcg tctctctgaa aaagatcatc aacatgtaca gcgtgcttta
    16921 gaagctgtag ggatgtggga tatgcgaaat cggcgaatag gtgaattgtc tggcggacaa
    16981 aagcagcgaa tcagtttagc gcgtattttt gctactgacc ctgacttatt tgttcttgat
    17041 gaaccaacaa caggtatgga tgaagaatcc agaaatgaat tttatcgtct tctccgacat
    17101 agtgcgcatg tccatgggaa atcagttcta atgatcaccc atgatcatga agatatcaaa
    17161 cagtatgcgg acagacagat ccgactggtg agaaaggagg attctcaatg gcgttgcttt
    17221 catatgaatt catgagaaga gcgtttcttg ccgctatctt cattgccgga atcgccccga
    17281 tgctaggtgt gtttttagtg atcagaagac aatcgctgat ggctgatacg ctttctcatg
    17341 tctctttagc aggggtagcg ttaggattct ttttgaacct taatcctaca cttacgacca
    17401 tgctagtcgt tgtattagca gctgtgatat tggagtatct gcgaacgatc taccgaacct
    17461 attcagaaat ctccattgcc attttaatgg ctggtggttt ggcgctagcg ttagtattga
    17521 tgaatttgag cggagggaat tcagcaacaa gtatccaatc ctatctgttt ggttcgatcg
    17581 tgaccattac atgggagcaa gtcatctttt taggaatctt attcgttgcc atcggtatat
    17641 tgttcttttt attcaaacgg ccgatgtatg ttctgacttt tgatgaagat accgcccacg
    17701 tggatgggct acccgttcat ttgatgtcga tgatgttcaa tgtgattact ggtgtggcta
    17761 ttgctgtgat gatcccgatt gccggtgcac ttttgatatc cgcaatcatg gttcttcccg
    17821 cagcaatcgg tatgcgatta ggcaaaagct tcaatgtcgt gattgctatc agtgtttgtg
    17881 taggatttct agggatgctg tcaggactaa ctagctcgtt ttatctagat acacctccag
    17941 gagcaacaat cacattagtc tttattgctt tgttcctgat tgtaaatatc atcaaacgaa
    18001 tattggttgc cttcagaaga aaaaataact aaattataaa gaaaagaagc cttataaaaa
    18061 cgaaaaattt tttataggct tctttttatt ttaataaata ccgaactatt ttcttatttt
    18121 ttcataaaat gctcgaattt ttgaagaaaa acttatataa tgtaaaacga taaaatttct
    18181 taaaaggagt tggaataggt gaaagtacgt cgcagtgaac gtctagttga catgacacag
    18241 tatttattga atcacccgca tgaattgatt tccttaacaa gctttgccga acgttatgaa
    18301 tctgctaaat cttctatcag tgaagatttg ggaatcatca agaaaacatt taaagaacga
    18361 gggtatggaa ccttggaaac aatcccgggt gctgcaggtg gtgtattgtt catccctgaa
    18421 atttcatatg aagaggcgaa aaaatatatt gaatctctag cagaacgtct atcagaacaa
    18481 gaccgtctgc ttccaggagg atatgtttat ctctctgatt tgttaggaga acctgaactg
    18541 ctgcgtcaag ttggaagaat cattgcttct aaataccttg gtgaaaaaat cgatgctgta
    18601 atgactgtag ccacaaaagg cgtacctatt gcccaagctg tgtcctatta tctgaatgcg
    18661 ccattcgtta ttgtacgccg ggactcaaaa ataacagaag gatcaacagt aagtgtcaac
    18721 tatgtgtctg gatcttctga aagaattgaa aagatggaac tgtctaagag aagtttgaaa
    18781 cgtggttcac gtgtccttgt agtggatgat ttcatgaaag gcggcggaac agtcaacgga
    18841 atgaagagct tgattgaaga attcgaatca gaacttgttg gcatcactgt atttgccgaa
    18901 tcaaaattca acggtcatcg cgccatcgat gattatacgt cactgcttta tgtcaaagat
    18961 gtagatactc aaacgaaaaa tattacggtt gtgccaggaa attatttttc agaataagag
    19021 gttgtgaaaa agccgcttag tttcgagtag taagaaaaat tttgtgaaaa tggctttcca
    19081 cattttttca taaatttggc ttaataccga gaaactggct tttgaacacc gtttatctag
    19141 aggttgtgaa atcagcgtcc tgtcctgagt attagctcaa taaacggaaa aattgctcct
    19201 catattttgc cgtttattga gctaataccg aaggtcagct gattgaaaaa cgtttaatga
    19261 agaggttgta agcctaccgt ttaactctaa gtcacaagaa acgatttcaa aaaacagctt
    19321 ttcatgtttt atgagtagtg tgacttgtga ccgaggagtt ggcaggagag caccggttac
    19381 caaatagata ggcccgttat ggtctatcta tttttttatc cagaaaacgc tgggataaaa
    19441 gaaaatcact tgttttgttg aaaaaatggg tatactggga taaactgaaa tcagcaaact
    19501 atatttagga gtgacgcagt tggacgcacg ttatgcaatt attttggcgg cagggaaagg
    19561 tacccgcatg aagtcaaaat tatataaagt tttacatccc gtttctggta aacctatggt
    19621 agaacatatc attaatcggg tcagtgaaac gaaaccagat gaagtgatta cgatcgttgg
    19681 acacggagca gaacaagtta aagcacaact aggagaacgc agtaaatatg cgttacaagc
    19741 agaacaattg ggaacaggac atgctgtttt gcaagctgct tctttcttgg aaggaaaaaa
    19801 aggaacaacg ttagttatca gtggcgatac accattattg actactgaaa cgctgaacaa
    19861 tctttttgaa tatcaccaag gaaaaaatgc aagtgcaacg atcttgacgg cacaagcaga
    19921 aaacccaaca ggatatggac gaatcatccg tgaccatatt gggatcgtag aaaaaatcgt
    19981 ggaacaaaaa gatgcaacac cagaagaagc tcttgtacaa gaaatcaata caggaactta
    20041 ctgttttgac aacgaagctt tgttcgatgc gttaagcaaa gttggaacaa acaatgctca
    20101 aggtgaatac tatctaacag atatcatcga aatcttaaaa gaagaaggcc atacagttgc
    20161 tgcttatcaa acggatgatt ttgaagaatc aatgggagtc aatgatcgga tcgcgttagc
    20221 taaagcaaat gagatcatga gaaagcgaat taaccagatg catatggtca atggcgtaag
    20281 ctttgtcgat tcagcaacga catacatcga tgcaggcgta gaaatcggtc cagacacatt
    20341 gatcgaagca ggtgtacaaa tccaaggaaa tacagtcatt ggttctgatt gtgtcatcgg
    20401 gtcacattca aaaatcgtag acagtaggat tgaggatcac gtcgtcattg aaaactcagt
    20461 cattgaaagc agccatgtca agaaacatgc agatgtggga ccttatgcac atttacgacc
    20521 aaaagctgaa attggcgaaa acgtccatat cggaaacttt gtggaagtga aaaatgctca
    20581 aatcggcaaa ggaactaaag tcggtcactt gacttatgtt ggtgatgcta cgctgggaga
    20641 agaaatcaat gtcggatgtg gtgttgtctt cgtcaactat gatggaaaga acaaacatca
    20701 tacgactgtc ggcgaccaca gctttattgg ttctagcacg aatatcatcg gacctgtcga
    20761 ggtagctaaa aacagttcga ttgctgccgg gtcaacaatt acagacaata ttccagaata
    20821 tgcgctggca attgcgagag caagacaagt caataaagaa ggatatgcaa aaaaactccc
    20881 ttatctaaac taagactttt gcaaaatcac ttgatttatt taaaaaatat gactactatt
    20941 tattaggtag aattctagag ttgtgaaaaa gaaagtggag gtccccatgt caaaacatta
    21001 ctttgaccca agattaaaaa tttttgcgtt aaattccaat cgcccattag cagagaaaat
    21061 tgcagcagca gtcggcgtcg agttaggaaa atcatctgtt actcaattta gtgatggaga
    21121 aattcaagta aacattgaag aaagtattcg tggatcgcat gtctatgtta ttcaatcaac
    21181 gagcagccca gtcaatgata acttgatgga gttgctgatc atgattgacg cactgaaacg
    21241 agcaagtgca aaaacaatca acgtagtcat gccttattat ggctatgcgc gtcaagaccg
    21301 taaagcacgt gcacgggaac caatcacagc gaaattagta gcaaacatga ttcaaaaagc
    21361 tggtgcaaca agaatgctga ctttggacct tcatgcagtc caaatccaag gtttctttga
    21421 tattccagtc gatcatttga tgggtgcgcc acttattgcc aattatttct tagaaaaagg
    21481 aatcaaaggc gatgatgttg tcgttgtttc accagaccat ggtggtgtca cacgggcacg
    21541 taaattagcg gaatttttga aatctccgat tgcgatcata gacaaacgcc gtccaaaagc
    21601 aaatgttgca gaagtaatga atatcattgg acaagtcaaa ggcaaaactt gtgtactgat
    21661 cgatgatatg atcgatacag caggtacgat cacattggct gccaatgctt tgaaagaagc
    21721 tggtgcaact agtgtgtatg cttcatgtac acatccagta ttatccggcc ctgctttaca
    21781 aagaatagaa gattcagcta tcgagcgtct agttgttaca gactcgatct atcttccaga
    21841 agatcgtaaa atcgacaaaa tcgatgaagt aagtgttggc ggactaatgg gagatgcaat
    21901 caaacgtatc catgaaaaca aaccagttag tccattgttt gaaacaaaaa ataaataata
    21961 aataaactca caaaggggag tccaattggg ctgagattga atctatttct aaacccttcg
    22021 tacctgtatc ggttatgcga gcgtaggaat tgtgaataaa cagctgtttg actattttcg
    22081 aaagctgctt cctcctttgt gactttttta ttcaaaggag gaagtttttt tatgggaaaa
    22141 aatagagttt gggtagaagg aacgattgtt gcagcgttag cgatggtgtt gtcgttgatt
    22201 ccgatccaga tcggcagcag tttttctatt tcattagggc agattccatt gactcttttt
    22261 gcgttaagaa gagggacaaa ggcagggatg ctggcaggtt tcatttgggg catcctacat
    22321 tttccgttgg gacaagttta ttatttaagt gtcgttcaag tgttgattga gtacccgatt
    22381 gcctatactt ttgcaggcgc agcagggctc atggcttcaa atgtccaaaa aggctatgta
    22441 gacgataata cgaaacaaat tagaaaaagc atcgtgtttg gtgcattgat tggcgcactt
    22501 tccagatatt tttggcattt tattgcagga gtggttttct ggggagcgta tgcactatgg
    22561 gggatgaatc cttggctctt ttctttcgta atgaatggtg ccagcgggtt gagtacagct
    22621 attgtaacga tcatcgtttt attagggatc caacaaacga ctccttcgat ttttgtgcca
    22681 gataaacgac aggagctgta aataaaaaag aagcaagaaa cttgagacag aatcatgtcc
    22741 tagtttcttg tttccttttt attttttgat aagaaataga tctacttcaa tggcagataa
    22801 gaaagatcgg catcttctac caattgccag tgtcgatcgg tgacagagta gattaaagta
    22861 gcgatgattt cctcttctcg ataccgggtg ccttttaatt tccaaatata atcttcaatc
    22921 acatagattg ggatacgata tttaccatcg atcaaaccaa cttgatcaaa agaaaaaatg
    22981 atcccttcct gcatcaaatt acgcatttct ttcaataatt ccacactgat tttttcaaca
    23041 ggtgtttctt ttttgaaaaa agattttttt acattgatct tatctgacaa gatcgaactt
    23101 aatttactag caaaaatcct ataaaattca tctaaatagc gataataaat ccgattcagc
    23161 tgatcattaa gatcgaagta tacaaaatta ttctgtagtt tataaaaaaa cggcgaatga
    23221 agatgtgttt tcatatgacc aaaatataat aattctgaaa tttctaaagg tgtcaattct
    23281 ttcagcatcg ttaaatcagt aaagtcgatc cacttcaatt catcgaatcc acgcctgtta
    23341 cgagaagagg aaaagaaacg ctgaatattt tctgtaccac ggattacttt cagccctgta
    23401 tgggattcat attctccagc agaagcagat ggatcaagca agagcaagtt ttgaggaaaa
    23461 tgcacgatac tgtttgcaaa gtcagtagca gtcagccctt ttgttaaaac agcattactt
    23521 gtggtatcaa tatgtacata aactgactca gtcatcatgt tcctcctctt atttcctctt
    23581 aatctctttt attttacaac atttgcatta aaaaagcttg tttcttttat tttaaaattc
    23641 cattacaaaa tcacgttttc attgaaaaca ctctcatttt caattaattt ttgtgatttt
    23701 tgtatttttt tatttaaagg aggttttatg aattgttttc ttatggaatc tacaaagtcg
    23761 aatacgagac tcatgacctt tttatgacgt actggtatac ttgaagaaaa aggagagcgc
    23821 gatggagata aaaaaagttt acttttcaca gaaaatgtcg ctgtattcgc ctatccagca
    23881 agcaaaacaa ccccttccat tttttcaaag tcatcaagaa agtagagacg ctttttggcg
    23941 ttctgcaaaa aagcaatgtg cttttaaagc agtatcgaaa aaatataccg tctattttac
    24001 tattgctaaa agtagaggag atgttatttt taataatctg ttgattgaag gtgaaacttt
    24061 tgaatggaaa aaattttttc ggtatatgga agcttgcgct cgttttttta ttaaagaaaa
    24121 ctgttgtttt ttatttcaat ctcctctatc agaagaatgg ttgcgtattt ttcataaaaa
    24181 cggctatcaa ggaaccacac aattaaataa aaagctggtc tatcatacag cacttgtttt
    24241 aggtggagga ggagcgcacg gtgcttatca gattggtgtg tggcaggcgc tgaaggaaca
    24301 tgatatcaac tttgagatta tcacaggtac ctcggtaggt gcgttgaacg gcgcattgat
    24361 tttacaagga gatatgaaaa aagctgtgaa tttatggaaa aagctgtcga caagacaagt
    24421 gcttgcgtta ccagaaatgg ctgcagttga agaccttcgt gaacgcttct atcgagaaag
    24481 acgccaaatg acgaaaacag cactaattga aggcggggtt tcttctgctc cattggaaaa
    24541 gatggtcaaa gacaatttgg atttgtcctt actcaaacat aatcccaaaa tacgtttata
    24601 tacggtgtct actaaactgc cagaactagc ggaagtagtg actgatatcc aacagacaaa
    24661 aacagaagaa ataccagatt ggatactcgc ctctgcttca ttttatcccg ctatggctta
    24721 tcgaaagatc ggaaaaaata aatatgcaga cggtgggtat cgcaacaaaa tacctattga
    24781 tattgcgatt aacaaaggag caacagaggc atttgtcgta gatgtgcaag ggccaggccc
    24841 agcgaaaaaa attcgtatgc cagacatttt tatccattgg aaatgtcaaa cattgtggac
    24901 actaggcagc tttctgcttt ttgatagcca aaggaaccaa ttaaatttac aattaggcta
    24961 tctggaaatg aaaaaacgat taggctatta ctatgggaac tggtatacat ttcattctgt
    25021 taaacctgca agaacatact ggcgaggatt tttgtcttac ttaacaaaag aaattcagtt
    25081 agaattatct tttttcaaaa gcataaaatt ttggcaaaaa ctgcgtaatt tatataagaa
    25141 cagggtcgta ccagagacat gcggattggc gatgctagaa cttttagcaa aaaaacattt
    25201 tttactgccc aatgaaatct atcaagtaga catgatgatt caaatgatct gccaacaaga
    25261 tataaaaagt atgccggatg atttattggc acaaattggt caattaagta ctgaagaatg
    25321 gcgaaggtat cgaaaatacc agcaaaaaat acaaaatgag cgcacgaaaa ctgtttattt
    25381 tgattatctg ctacaaggaa aacgcaagga tcgtttgcag catgaattgc ttaagcaacc
    25441 agttgacaca ttactgatcc tatatttata ttatctcaag gaggaacaac catggcacaa
    25501 gaattttcat atgaaatcgt agaagaaatc gctatattgt cagaaaacaa caaggggtgg
    25561 cgtaaagaac tgaacctagt cagctggaat ggtcgcccgc caaaattcga tcttcgagat
    25621 tgggcgccag accatgaaaa aatggggaaa ggcctgacat tgacgaacga agagtttgaa
    25681 caactgcaaa aagcaataga aaatatgtaa tgaggaagga ccctgtcgaa tgaaaagtat
    25741 gactggtttt ggcaaagcca tccgcgaaac aaaagcgtat cagttagata ttgaaataaa
    25801 aagtgtcaac cagcgttttc tagatgttca aatacgaagt cctaaaatcc tgaactttgt
    25861 tgaaaacgat tttcgtcagc ttattaaaca gcagttaagc cgcggtcgaa tcgaagtatt
    25921 tgtgaatcta gcttatattg gcaaaaacga aaaacagatc gtcatcaact gggaattgat
    25981 tgattcactt atcactcaat tgacagacgg aattcaacaa cgatacggta gtcaaaatca
    26041 agtgtcaatt agtcggatgg cggaacgctt cgtgctggac gaaaacttcg taacggtaga
    26101 agaaaaaccg gaagagagca tggaagaatt ggcacagtta gctctagata cattgaaaag
    26161 cgcacttgat tctattgagg cgagtcgaga aaaagaaggt caagctttag ctttagtgtt
    26221 gaaaaagaat actgaagaat tcaaagaagt actaaaaaaa ctcgatagtt ttgtagaaat
    26281 ctatgaaaag gaatttcaaa taaggtatca aaaaaagctg gaggaatttc ttggagcgaa
    26341 agtcgatgag caacggttgt tgacggagct agccatcttg ttggaacgcg gagatattca
    26401 cgaggaactg gatcgtctgg cgatccatgt acaaaaacta gatgaactta tcgaagcaca
    26461 atgtcctgta ggtcgggaat tagatttcct gatccaagaa atgaatcggg aaatcaacac
    26521 gatcggttcc aaatcaaatg caatcgaaat taaaaatcaa gtcgtccagt ctaagacgat
    26581 cttagaaaaa atcagagaac aagtacaaaa tattgaatga cgaaagaggt agagataatg
    26641 aaatattatg acgtaacgtt ccacgaatta agtggaaaaa ctgtggttaa acgggatatc
    26701 ccttctgaaa aaaacggctt tgacgtatgg aaagatgcct gtgcagacta taatgagaac
    26761 gaactgttta ttttgatcaa cgacggtgct tacgtgacga tgaatcggaa atttattgtt
    26821 cgaattgaca cagaagaggt agaagatccg acagaaaaag cacgttctcg aaaagatgag
    26881 atcatgggtg tagtgaatac tttgtccaat atgggctttt agcaaggatg ctgaacaaag
    26941 aaatacaata aataaacaga attggatttc ttcgcttagc ttctttgctc taggaataca
    27001 tttaaaggtt gtgacaaaat tcgtgtcaca atcttttttt attttgaata agtgatgttc
    27061 aaaaaccatt ttctcggtat taagccaaat ttatgcaaaa atgtgagaaa ctattttcac
    27121 aaaatttttc ttcatactcg aaactaatcg gcttcttcac gacctcttat acacggcgtt
    27181 caaaagcttg catctgcgat aataacccca accaaacgaa aaacatgaga agctgtttat
    27241 gtttggctgt tcttattact tgatgcagga cagctttttt acgacctctt ggtacagggt
    27301 agctttttta ccaatttcta gctataatta aagataacct tgaaagttgc agaaaaaaag
    27361 tgcaaaataa acgataagta caaaaagact agttgaaagg acgtcgtcat gtcagagcgt
    27421 ggattattaa tcgtgttgtc tggtccatcc ggtgtaggaa aaggcacagt acgaaaagca
    27481 atttttgaga gtgaggataa tgattttcag tattcgatct caatgactac ccgtaaaatg
    27541 cgtgaagggg aggtcgaagg cgttgattat ttcttccgaa gcaaagaaga gtttgaatca
    27601 atgatcgaag ctggagagat gctggaatac gcagaatatg tcgggaatta ttatggaact
    27661 cctttgtcat atgtcaacaa gacattggat gaaggaaaag atgttttctt ggagattgaa
    27721 gtccaaggag caaaacaagt caaagaaaaa gtgcccgatg gtgtattcat ctttttgact
    27781 ccgccagatt tagcggaatt aaaatcacgg atcgtaggcc gaggaacaga tgcagatgaa
    27841 gtaatcgaaa aacgaatgaa agttgcaaaa gaagaaatcg aaatgatggc tctttacgac
    27901 tatgctgttg taaatgatga agtgccgcta gcagttgaac gaatcaaaaa cattattgcc
    27961 agtgaacatt ttcgagtaga tcgcgtaatc ggtaaatata ttaaaatgtt aaaggagatg
    28021 tagtcttatg atgttaaaac cttcaattga ctcactatta gatcgtgtaa attcaaaata
    28081 ttctctagtg attttagcaa gtaaacgcgc gcatgaattg gatgcaagtg cacagcctac
    28141 tctagattct tttgattcag taaaaagcgt cggtcaagct ttagaagaaa tcgatgcagg
    28201 aaatgtagtc aatgatccac atcctgaatt aaaacgtgaa cgtttgaaga tggaagaaga
    28261 ggaacgtcaa gcacaaaaag agcgtgaaca acacgaattg gaatcacgta tccgtgaaga
    28321 gcaaaaaatg taataaagaa aaatagagcg aacatctaaa aagaaaagca aacccagctg
    28381 tttccttttc aaacattcgc cacttattgt ctggtagaaa aggctgtgtc tgaacttttt
    28441 gacacagttc ttttttttct tatctgctgt taattttttg ttaggatttg gcagaagata
    28501 agacaaatcc atcgatctct agtaaaatag gcaaggaact ttttgtcgct tgataagaaa
    28561 agacaaaaaa aggaggaaac gaaccatgac attaacagct gaagtcattg tggacgtacc
    28621 tactatgcag accgatcagc cattcactta tttggttccc tctgaaatgg aaacagcttt
    28681 gcaagtcggg atgcgagtag aagtcccttt tggtaatggc aatcgtcatg tccaaggatt
    28741 tgttatggct atccaaaaat cagaagaatc agctaatcca tctttgaagg cagttattcg
    28801 tttgctagac cttgctccgg tggtcaatga agaattactt tcattagctg attatatgaa
    28861 aaaaattact tacgcattca aaatcacttg tctacaaacg atgcttccga gtgtgatgaa
    28921 agcagaatat gataaattga tctatccttt ggcagacaca ccagaagttc aggtattgtt
    28981 tgatcagcga gaagtgattt cctggaagga agcagaagaa gaaggcagcc tttctcaatt
    29041 gattcgctgg cgccaagagc aattagtaga tatcaaatat gaagtccata cacgaaataa
    29101 agtaaaaacg attcgtttgg tccgttcttt gttaactgaa aagcaaatcg aagaagaatg
    29161 ggcaaaatta cggcaaaatg ccaagaaaca aaaagaactt cttttgtgtt tatctgaact
    29221 gagccaagaa gaaccaattg cttatttcaa aaataaagga atcagtactg ctgtcttgaa
    29281 tcaaggaaaa gaaaagggct ggctggagtt tatagaatca gaacgttatc gcgaccctta
    29341 taaagaccga gtatttgacc aaacgacggc attggaactg aatgcagaac aaaaaaatgc
    29401 tgtcgaacaa atcatcacag caggtcagca gcaaaaagat caggtctttt tgctggaggg
    29461 aatcactggc agcgggaaaa cagaagtata tcttcaggca atcgctgatg ttttgtcaga
    29521 aaataaaacg gctattatgt tagtgcctga aatcgcattg actccgcaaa tggtcgagcg
    29581 attcaaagga cgcttcggag aatcagttgc ggtcttacat agcggacttt cccaaggtga
    29641 aaaatatgat gaatggcgca agattgagcg ggaagaagcg caagtagtag taggcgcacg
    29701 atctgctatt tttgccccgc tgaaaaatat cgggctgatc attatcgatg aagaacatga
    29761 atcaagttac aaacaagatg agacaccgcg ttatcatgcg agagatctag caatttggcg
    29821 cagtaaatat catcattgcc caatagttct aggaagcgcg acgccctctt tagaatcaag
    29881 agcacgagct caaaaaggcg tttatcagtt attgcagtta aaccaccgag ccaaagcagc
    29941 tgcacagctt ccagctattg agatcgtaga tatgcgtgaa gagtttcaga atcatcggac
    30001 ctctactttt tctgctaatt tgcaggaaaa aatacaaaat cgattagaca aaaaagaaca
    30061 aactgtccta ctgctcaatc gtcgaggata ttcgtctttt gtgatgtgta gggactgtgg
    30121 atttgttctt ccatgtccta attgcgatat ctctcttaca ctgcatatgg atacacgttc
    30181 aatgcgctgc cattattgcg gacatgaaga acctattccc aatcgctgtc ctaattgtgg
    30241 cggcaataaa atccgctact atggaacagg tactcaaaaa gtagaagagg aactccgaga
    30301 actttatccg caagctagga ttttgcgtat ggatgtagat accactcgaa gaaaaggggc
    30361 acacgaacag attttacaaa aattcggtgc aaaagaagca gatatattat tagggacaca
    30421 aatgattgct aaaggtttgg actttccaga agtgacatta gttggggtgt tgaatgctga
    30481 tacctccctg aatttaccgg attttcgttc tagtgagcat acattccaat tgcttaccca
    30541 agtttcagga cgagcagggc gagcggaaaa agcaggcgaa gtcgtgatcc aaacattcaa
    30601 tcctcaacat tacgccatag aattggctaa aaaacaaaat tatgagcagt tttatcagca
    30661 ggaaatgcat gtacggcatc gtggaggcta tcctccttat tactttactg tgaaaataac
    30721 cgccagccat cctgaagaac aagtagcggc aaagaaaatc tttcagattg ccaatcagct
    30781 aaaagaagtg ttaagccctc aaagcttgct attagggcca acgcccagca tgattttgag
    30841 agtgaaaaac cgatattatt atcaactaat catcaaatat aaacatgaac cgaatcttcc
    30901 tcatgttttg gatgaaattt tgaatggaag ccagaaagaa cagcgacaag gtctttttgt
    30961 ggcaattgac aacgaaccat taaactttat ttaagaaagg gccaaattat gcgctatcct
    31021 atattgatcc accctaatga taaattaaaa agaactgctc agccaatcga tgtaatcacg
    31081 gacgagacaa tcgctttatt agacaattta tatgagacaa tgattgcgaa tgacggaata
    31141 gggatcgctg ctcctcaagt aggacaaaac aagagaattg ctgtgatcga agtagatgaa
    31201 ggcgagaaat ttgaactgat taacccagaa atcatcgaag caaaaggtga aagccttgac
    31261 gtagaaggtt gtctcagtat tccgcatgtc tatggaacgg tcaagcgagc agatgaagtg
    31321 accgtgcgtt attatgatcg agacggagaa gagatagaag tgacggcttt tggctattta
    31381 gcccgtgcct tccagcatga aatcgatcac ttagacggta tcttgttcat tgagaaaatg
    31441 atacagcaga tcccggaaga agaacttgaa gaatatatgg aggaacatct tgatgactaa
    31501 gctagtattt atgggcacac ctgctttttc tgtgccgatt cttgaagggc tgatagaatc
    31561 aggttacgag atccaggcag tggtaacaca gcccgaccgt ccagttgggc ggaaacgagt
    31621 aattacgccg acaccggtaa aaaaagcggc tctgaagcac ggtatccgtg tgctgcagcc
    31681 agagaaaatc tccggttcgc cagaaatgga agaaatcatt gaattggtgc ctgatgtgat
    31741 cgtcactgcg gcatttggcc aattcttgcc tgaaaagtta ttgcaagtac caaaattagg
    31801 ggcaatcaat gtccatgctt ctttacttcc taaatatcgg ggaggtgcgc ctgttcatta
    31861 tgccatcatg aatggggaga aagaaactgg tgtaacgatc atggaaatga tcaaaaaaat
    31921 ggatgcaggc ggaatctatg cgcaagaaag cataccaatc actaaacaag atgatgtagg
    31981 gacgatgttt gaaaagctta gccttttagg aagaaagcta ttgctagaaa cattgcccaa
    32041 tattttggat ggacaaaaac cagtacctca agacgagtca gaagcaactt tttcgccaaa
    32101 catcacacgg gaacaagaag caatcgattg gcataaaact gcagaagaaa ttgacaacca
    32161 agtacgcgga atgcgtcctt ggccaattgc attcacgacc tatgagggca tacgctggaa
    32221 attattatcg gttgaagtat tggcagaaac tacagacaaa gcacctggta cgatcatccg
    32281 gaaagacaaa aaaaatctat ggattgcttg cggtaaacag accgtcttag ccatcaatga
    32341 attacagcca gctggtaaag gaaaacaggc cgtacatgat ttccttaacg gaagcggtca
    32401 gcaagttcag attggtcagc aggtgaaata atgaaaaaaa tccctaaaaa aatgaaaaaa
    32461 tcagtacgat atatggcatt actgacatta gagcgagtga acaagggtgg cgcctactcg
    32521 aatcttttgt tgaatgagat gatcaaacaa agcgagctaa atcaaaaaga tgtgggttta
    32581 tttacagaat tgatctatgg tacgattagc catcagcgac tattggaatt ttacgttgca
    32641 ccattgatcg ctaaagcaaa aaaagtggat gactgggtca agatgcttct ttatctttct
    32701 gtataccaat tagaattttt agataaagtc cctgcacatg ctattttaaa cgaggcggtc
    32761 gaaatcgcaa aagtaaaagg aaatcctggg acagggaaat ttgtaaatgg tgtcttgagg
    32821 aattatcagc gtcaaggagc accagatctg caaggcattg ctgatcctat cgaaagactt
    32881 tctgtcaaaa tcagcctgcc tctatggatg acgaaacgac tggtggatca aatcggatac
    32941 gaagaaactg aaaagctcgg tttatcgcta tatcagccta gccatgctag tgcccgagta
    33001 gatacacgcc gactttccag agatcaggcc atcactgttt tgcaagaaga agagatcaca
    33061 gctgaaaaaa gccaagtcag tccatacggt atagtagcga aaaaagggca tttagcttct
    33121 agctcattgt tccacgatgg cgtcatgacg atccaagatg aaagttcgat gcttgtagcg
    33181 ccgtctatgc aaatcgagcc tgaacatcat gtcttagatg cctgtgcagc acccggaggt
    33241 aagacgacgc atattgcttc ttttttagat ccgtcatgcg gtggagaagt ggtcgcttta
    33301 gatgtacacg aacacaaagt caaactcatt gaagataatg cagcacgtct aggtgtctct
    33361 tctgctgtct acgctcaaaa gatggatgct agagaagtca gtaaacagtt cgaagcagag
    33421 cagtttgatc ggattttagt agacgcgcct tgttcaggtc ttgggctgct tcggcgaaaa
    33481 ccagatattc gttataaaaa acagccggat gaattagcga atttaccaaa aatccaattg
    33541 gaaattttag aaagctgcgc accaacttta aagtcttccg gtattctgac ttatagcact
    33601 tgtacgatct taaaagaaga aaaccaagac gttgtttctg ctttcttgga aagacaccct
    33661 gattttgaga ggattgatgt tttgaccaat cctatgctac aatcatcaat cgaagagaaa
    33721 atgttgactt tgtatccgca tcagttttac acagatggat ttttcatttg ttgtttgcgc
    33781 aaaaagtaat gaggtgaaaa aatgcagatt gaatatcaat cagatgtagg aagacgacgt
    33841 aacacaaatc aagactatgc cagtgtattt accagccgtt caggtctcaa gcttgctgta
    33901 ttagcagacg ggatgggtgg tcatcgtgcc ggagacattg ccagtcagat ggcggtaacg
    33961 aatctaggcg aagcttggga aaaacaagaa gctgttgacg atgaaaaaat cgcccaatgg
    34021 ttcattcaat cgattcaaga agaaaatatg ctgatttatc agcgtggaca agaacagccg
    34081 gaatataacg gtatgggaac aacaatcgta gcggccgctc tgtcagatga ctggttcacg
    34141 attgccaatg ttggggatag cagagcttat ttgattcgtg aagataaaat catgcaattg
    34201 acggaggatc attctttagt caatgaacta gtcaaatcag gagaaatcag cgaagaaatg
    34261 gcagtgaacc atccaaggaa aaatatttta acacgttctg tcggcatgcc tggaacagtc
    34321 gaagtagatg tttctactca tctttggcaa ctaaaagatc gactgctgtt atgttcagat
    34381 ggcttgacga acatgctgtc tgaagaagaa ataggaacga tcatcaatca agaaggccca
    34441 ttgtctcata aagtaactga gctgattgat cgtgccaatg aagcaggcgg agcggataat
    34501 atcaccgttc ttcttatcga atataaggag gacagtgtat gatcgagttg ggcaaaaaat
    34561 taaatggccg ttatcaaatc actggaaata tcggtagcgg tggtatggca aatgtatttt
    34621 tggcgcacga tttaatcttg gatcgtgatg tagcagttaa agtcttacga tttgactttc
    34681 aaaatgacca gactgcgatt cgacgatttc agagagaagc tttagcagca acagaactcg
    34741 ttcatccaaa cattgttagt gtttacgatg ttggtgaaga agacaacatg cagtatctgg
    34801 tgatggaata cgtcaaagga atggacttga aacgatatat ccaaacacat tatcctgttc
    34861 cttatgaaac agcagtaaat attatgcagc agatcctttc tgctatttct ttagctcata
    34921 accatcaaat catccaccga gatttgaaac cccaaaacgt actgatcgat aatgaaggtg
    34981 ttgtaaaaat cacggatttc gggattgcta tcgctttatc tgaaacatcg atcacgcaga
    35041 cgaatacgat gctaggatct gttcattatc tgtcccctga gcaggccaga ggaagtatgg
    35101 caacgaagca gtcagatatt tatgctttag ggatcatcct ttatgagatg ttgacgggta
    35161 gcgtaccgtt tgatggtgaa tctgctgtaa caattgcttt aaaacatttt caagatgatc
    35221 ttccatctat aaaagcactt gatccaaatg tgccacaagc actggaaaac gtgattttac
    35281 gggcaacggc taaagaacct gcagaccgtt ataagtcagc cgaggaaatg tctgatgatc
    35341 tttctacagt attatcacca gctcgtgcaa acgaagaaaa atggcagcct catgtgatgg
    35401 ataatgaaac aaaagttatc acacccctta cggaagatgc accaatgcct gattcattca
    35461 aatctatgcc tctgccaaaa gacaagccag aaaacgaaac cttaccagag gaggaagaag
    35521 ttctgcctga tcctaaaaag aaaggacaga aaaaatggtg gctgatccta ttagctattc
    35581 ttgctgtttt aggaatcgga acagctgtat tctttgcttc tggcgggcga ggagaagttg
    35641 ttgttcctga tgtttctgat ctttctgaag cttctgctag agaaacactc gcaaaagcga
    35701 aattagaagt agcaacaaaa acagaagaaa ttgcagatga caaaatcgaa gaaggtaatg
    35761 tagtgaagac agacccggca gcgggaacga cagtcaagca aaaacgcgaa gtcactctgt
    35821 atattagtag cggcacgaaa aaaatcaaat tagatgatta cagtggtaaa agttatgaag
    35881 atgccgaagc aagtttgaaa gaattagggt tttctgctga cttgattcaa aaagaagagg
    35941 aattcagttc agaggtagaa agcggaatga tcatttcgca atctccatca gaagatacag
    36001 aagtcgatcc taaaacagac acgattactt tcacagtcag caaaggacca gaaacagtga
    36061 ctttgagtag tcatgtagga gaaaactacg aaactgttcg taattggctt gttacacaag
    36121 gattcaatat caataatatt agtgctactt atgactatag cgacactgta ccatcaggtt
    36181 cgatcatcag tcaggatcca gcctcgggtg aagttgtagc agaagaaact tacatcaatt
    36241 ttgtcgtaag ccaaggaaca gagcctaaat tgaatgatat ctccggctat acaaaaagcg
    36301 aagcacaaag ttatttagct agtgtcggtg cagaatatat cgggcatgag acttccgaat
    36361 attcaaacac ggtggataaa gataaagtga ttcgtacagt accaggggca ggaacgacaa
    36421 ttaccaaagg aatggttgtg aacgtaattt actctaaagg accagatcca gcgtcttcta
    36481 gttctgaaaa agactcttca gacagttcta gcagctcaag tagctccagt agcacaagca
    36541 actcttcaaa agaagaatct tccagctcca caagttcatc agctagcacc tcagaaagtt
    36601 caaaataagt gctgaataaa atatatcaga agggaatgcg acattgattt gttgcattct
    36661 cttttttgtg tttctatctc ttttgatcaa ttttcaagcc atatactttg agaagtttgc
    36721 atggaataac acctactttc ctcttcgtat ggtaaaataa acaaaaacgg aggtggcact
    36781 tatcaaagga caaatcagaa aagcaatcag cggtttttac tatgtatacg caaacggaga
    36841 gacctatcaa acaagaggaa gaggaaattt ccggaatcgg aaaatcacgc cgcttgtcgg
    36901 agatcaggtg atctttgaga gtgaaaatca aacagacggc tatcttctgg aaatcttgcc
    36961 gagaaaaaat caattagttc gcccaccagt cacaaatgtt gatcttggaa tcattgtcac
    37021 aagtatcgta gagcctgcat tttcttataa tctacttgac cgctttctag ttaccttgga
    37081 atacgagtcg atcgaaccga ttattttttt gacaaagacc gacttgtcag acgacccaga
    37141 aaaaatcgaa gagatcaagc aaacctatac taaaataggc tatccggtga ttgtacccaa
    37201 tcatacgggt gatacgacag aactgatccg ttacttccca gaacggctat cggtctttat
    37261 gggtcagtct ggagcaggaa aatcgacgct actgaatcaa atatcaccgg aactgaattt
    37321 agcaacagga gagatttctg atgcacttgg aagaggacgg catacaacac gtcatgtgga
    37381 actgattcct atctatggcg ggttagtagc agatacacca ggatttagct cgattgactt
    37441 tttgacaatt gaagcaggag aactgccgag acaatttcct gaatttgtag aagcttctgt
    37501 ccattgcaaa tttagagagt gcatgcatgc taaagaacct ggctgcgaag taaaacatag
    37561 agtagaaaca ggtggtatcg cacagacacg ttacgacaat tatttgcaat tcttacaaga
    37621 aatcgaaaaa agaaaaccaa tgtatgcaaa aaaagaaggt aaacgaaaat aggaggaaac
    37681 aagaatgaag atagcaccat ccattttgag tgcagatttt gccaatttac aaagagacat
    37741 tgagttagtg gaaaaaggag gcgcagatta catccacgta gatgtaatgg atggccgatt
    37801 tgtcccaaat atcacattag ggccaaatat tgttcaggca atccgtcctg ttactaaatt
    37861 accgttagac gtccatctga tgatcgttga tccagaaaac tacattccag catttgcaaa
    37921 agctggagca gatatcatta ctgtccacgt cgaagcaact cctcatattc atcgggcact
    37981 tcaaatgaca aaaagcttag gagttaaagc tggagtagtt atcaatccag gaacaccagt
    38041 ctccatgatc aaacatgttt tgcctttggc tgatcaagta ctagtcatga ctgtcaatcc
    38101 tgggttcggc ggacaaagct ttattgaaga aacagtagaa aaaattacgg aactcgctga
    38161 tctacgtaga gagaacaatt ggacttatgc aatcgaagta gatggcggaa tcgttccaga
    38221 aacagcaaaa atctgtaaag atgcaggggc ggatgtcttc gttgcaggat catatatcta
    38281 tggagccgaa aatccagtcg gacaaatcga acgattaaaa gaggcattag actaaatgaa
    38341 aattttatta gctgctggag gtaatccgca aaactggccg cagtctctgc tgtccaaata
    38401 cgatgcctat gtcgggatag accgtggtgc gctgtacctg cttcaagcag gctacccagt
    38461 agatctggca gtgggtgatt ttgattcatt gtcgaacgaa gagcagaagg aagtatttgc
    38521 aaaagccaaa gagtataccc gttcccctgc agaaaaagac gatacagata cacagttagg
    38581 tatcttaaaa acatttgaac gttacccgca agcggaagtc actttgattg gagctacggg
    38641 cggaagattg gatcatcttt tagccaatct ctggttaggt atggaacctc gcttcaaacc
    38701 ctttgcccat cagcttatta tcagagattg tcaaaattat ttgtcttatt atttgcctgg
    38761 agagcatata gtaagacaga taccagatat gaagtattta gcttattgct gcttgactcc
    38821 cgtctcgaat cttacattaa aaggcagcaa gtatgtattg gaaaataaag aagtagaata
    38881 tccgacatct tatgcaagta acgaatttct ttcagatacc gcagaatttt ctttttcaga
    38941 tggtatgatt gcagttattc aaagcaaaga ttgatccata aacaaataaa aaaatttgtc
    39001 tttcaggcta aaaatgacag aatctattat ttgctaaaaa aaagcttaag aggagcaact
    39061 taccttttgt ttcacggcat ttagtgataa aattgaacac aagagtctaa ttaattcgag
    39121 gtgtctttgt gaagaagttc aatcctaata aaaatattat tattaccttg gttattgtta
    39181 tcatcgtggt gacgatacta agtgtgaccg ctgcgcagcg agcgaatgaa ggaaagccca
    39241 atttcttcca atccatcgtt aatgacagtg ttgcaatggt tgataaaaca atctctgccc
    39301 cagtacggtg ggtacgaaat ggagtagatt ctgtccataa tcttttttca acttatgccg
    39361 aaaatgagcg gctaaaagaa aaaatcgata gctatgatga cgtttcacag caaaacaaga
    39421 attacgagag agaaatcgaa gcgttgaaaa aagaacttga gttgaatcag acgctgacta
    39481 gttacgaaaa agtaacggca aatgtcatta ctcgttcgcc tgacagttgg caggacatgc
    39541 tgatcgtaga caagggttct aaagacggta tcgaagcaaa tatggcagtc atgtcgcaaa
    39601 aaggattgat tggccgagtg atcgaggtca atacggcttc gtctaaaatc gaattactgt
    39661 catcctctaa tgaaagctcc aatcattttc cagtacgggt atcttcggct aatggcgaag
    39721 cgtttggttt gcttaaaaac tatgatgaaa agctccatgc cttagtggtg acccaattaa
    39781 ctggtgatac ggatatcaaa gaaggggatg ttgtccagac atccggtctt ggagggaatt
    39841 ctccagctaa cttgccgatc ggtacggtta ttaaaacgaa accagatagt tatgggctgg
    39901 atcgggaagt ttatgtgaaa ccttatgcag aaatgtatga cgtgtcagtt gtgacgattg
    39961 tccaacggct agcggaggat tagtccatgt tgaagaaaga aacaatgaag tactatctgc
    40021 caatcgtttt gttctttttg atgttgatag atggtcattt aacaagaatg ctaggggagt
    40081 ggtcgaaagg cacctatatg tcaaatgccc actttctgat attggcatta ttatgttgca
    40141 gtatggcgtt tgaaaaacgt tatttactga ttaccacgat tgttctcggg gctatctatg
    40201 acgcttacta tattggcgtt atcggtatct atgcagtagc tctcccttta attgtatggt
    40261 tgatgtatgt aatgaaagac gttatccatg tcaacatctt tactgaattt ttcagtatga
    40321 tcatctttgt cacgggttat gaattgttta cgatggtggt ccagttgatt tttaaattag
    40381 cagtagtaaa taacacgtat tttattacaa ggtttttagg acctacactg ctgttgaaca
    40441 tgattatatt tgtattattc atttttccct ttaagaaatt attcagtgat gaataatttc
    40501 tttttttatt tttaggtcga aagcgaaaaa gaatcgttgt tatcttaaga aatgctagac
    40561 ttaacgcggc tttttcatga tcattttctg aaacgaacag ttttgtcatt tttaaaagtt
    40621 gttttgaaac atttttgtaa cataactatt atatcgttga cacactgcta tggtacaatt
    40681 tttatatcgt taagaaagac ttaaatatat ttagatattt attaaattaa gccagtcgga
    40741 ggaatgaag
//
LOCUS       DAFTHM010000013        39613 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFTHM010000013 DAFTHM010000000
VERSION     DAFTHM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.013"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..127
                     /locus_tag="L7C88_000722"
     CDS             <1..127
                     /locus_tag="L7C88_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBP9557577.1"
                     /translation="KNKQLPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(253..1332)
                     /locus_tag="L7C88_000723"
     CDS             complement(253..1332)
                     /locus_tag="L7C88_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBP9557578.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(1435..1875)
                     /locus_tag="L7C88_000724"
     CDS             complement(1435..1875)
                     /locus_tag="L7C88_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBP9557579.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(1932..2342)
                     /locus_tag="L7C88_000725"
     CDS             complement(1932..2342)
                     /locus_tag="L7C88_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBP9557580.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(2522..2956)
                     /locus_tag="L7C88_000726"
     CDS             complement(2522..2956)
                     /locus_tag="L7C88_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBP9557581.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(3056..3904)
                     /locus_tag="L7C88_000727"
     CDS             complement(3056..3904)
                     /locus_tag="L7C88_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBP9557582.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            4293..6059
                     /locus_tag="L7C88_000728"
     CDS             4293..6059
                     /locus_tag="L7C88_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBP9557583.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            6161..7420
                     /locus_tag="L7C88_000729"
     CDS             6161..7420
                     /locus_tag="L7C88_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBP9557584.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            7567..8868
                     /locus_tag="L7C88_000730"
     CDS             7567..8868
                     /locus_tag="L7C88_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9557585.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            8871..9722
                     /locus_tag="L7C88_000731"
     CDS             8871..9722
                     /locus_tag="L7C88_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9557586.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            9735..10550
                     /locus_tag="L7C88_000732"
     CDS             9735..10550
                     /locus_tag="L7C88_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBP9557587.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            10701..11867
                     /locus_tag="L7C88_000733"
     CDS             10701..11867
                     /locus_tag="L7C88_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBP9557588.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            12097..12744
                     /locus_tag="L7C88_000734"
     CDS             12097..12744
                     /locus_tag="L7C88_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBP9557589.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            12828..13772
                     /locus_tag="L7C88_000735"
     CDS             12828..13772
                     /locus_tag="L7C88_000735"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBP9557590.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            13907..15358
                     /locus_tag="L7C88_000736"
     CDS             13907..15358
                     /locus_tag="L7C88_000736"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBP9557591.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            15379..16215
                     /locus_tag="L7C88_000737"
     CDS             15379..16215
                     /locus_tag="L7C88_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBP9557592.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            16215..16874
                     /locus_tag="L7C88_000738"
     CDS             16215..16874
                     /locus_tag="L7C88_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBP9557593.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            17000..17689
                     /locus_tag="L7C88_000739"
     CDS             17000..17689
                     /locus_tag="L7C88_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557594.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            17695..18651
                     /locus_tag="L7C88_000740"
     CDS             17695..18651
                     /locus_tag="L7C88_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBP9557595.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            18695..19207
                     /locus_tag="L7C88_000741"
     CDS             18695..19207
                     /locus_tag="L7C88_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9557596.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(19463..20011)
                     /locus_tag="L7C88_000742"
     CDS             complement(19463..20011)
                     /locus_tag="L7C88_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9557597.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(20100..21281)
                     /locus_tag="L7C88_000743"
     CDS             complement(20100..21281)
                     /locus_tag="L7C88_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBP9557598.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(21517..23025)
                     /locus_tag="L7C88_000744"
     CDS             complement(21517..23025)
                     /locus_tag="L7C88_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBP9557599.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            23184..23375
                     /locus_tag="L7C88_000745"
     CDS             23184..23375
                     /locus_tag="L7C88_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557600.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            23578..24495
                     /locus_tag="L7C88_000746"
     CDS             23578..24495
                     /locus_tag="L7C88_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBP9557601.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            24488..25561
                     /locus_tag="L7C88_000747"
     CDS             24488..25561
                     /locus_tag="L7C88_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557602.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            25709..26227
                     /locus_tag="L7C88_000748"
     CDS             25709..26227
                     /locus_tag="L7C88_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557603.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            26208..26600
                     /locus_tag="L7C88_000749"
     CDS             26208..26600
                     /locus_tag="L7C88_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBP9557604.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            26676..27611
                     /locus_tag="L7C88_000750"
     CDS             26676..27611
                     /locus_tag="L7C88_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBP9557605.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            27744..28523
                     /locus_tag="L7C88_000751"
     CDS             27744..28523
                     /locus_tag="L7C88_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBP9557606.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            28516..28833
                     /locus_tag="L7C88_000752"
     CDS             28516..28833
                     /locus_tag="L7C88_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBP9557607.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            29077..30687
                     /locus_tag="L7C88_000753"
     CDS             29077..30687
                     /locus_tag="L7C88_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBP9557608.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            30844..31692
                     /locus_tag="L7C88_000754"
     CDS             30844..31692
                     /locus_tag="L7C88_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBP9557609.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            31923..32402
                     /locus_tag="L7C88_000755"
     CDS             31923..32402
                     /locus_tag="L7C88_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557610.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            32435..34663
                     /locus_tag="L7C88_000756"
     CDS             32435..34663
                     /locus_tag="L7C88_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9557611.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            34792..36435
                     /locus_tag="L7C88_000757"
     CDS             34792..36435
                     /locus_tag="L7C88_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBP9557612.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(36508..37053)
                     /locus_tag="L7C88_000758"
     CDS             complement(36508..37053)
                     /locus_tag="L7C88_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBP9557613.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(37076..37561)
                     /locus_tag="L7C88_000759"
     CDS             complement(37076..37561)
                     /locus_tag="L7C88_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBP9557614.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(37551..38363)
                     /locus_tag="L7C88_000760"
     CDS             complement(37551..38363)
                     /locus_tag="L7C88_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBP9557615.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(38502..>39613)
                     /locus_tag="L7C88_000761"
     CDS             complement(38502..>39613)
                     /locus_tag="L7C88_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBP9557616.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        13058 a         7157 c         7767 g        11631 t
ORIGIN      
        1 gaaaaataaa cagctaccaa aatccggaga gtcacaaaac aaagttatac tgtggagcgg
       61 aatcattcta ttaagtatag caacaatgct ttctgcaaaa agatttaaac aaaacagatc
      121 tctctaacat ttgaataatg tctgtgaacg catttttcaa ataaaaagaa atatccagaa
      181 aatgacccca aaataccaga ttgaaatctg atatttgggg tcgttcatac tttatctttc
      241 ttcatattta ttttaaggga tatctgtttc ttttggaaga tggttcggga tctttttcac
      301 tttcaataca tctaaaaaga aggtaaagat cggaatgccg acaatcaagc cccaaacgcc
      361 aaagaaccgt tcgctaacaa gtaagaccac aaatgtataa aaaatcggca gttctgtttt
      421 gctggacatc aacttcggat tcagcacata agactcaatt agatggacaa tcaaaatcgt
      481 aatcaggata taaacaacat ctcggatgcc tccttgggaa taagctatga aagatagagg
      541 aatacaagaa atgataacac ctgctactgg gatcagactt aaaatgaaaa tcatgatcgc
      601 taaactcagc agctgatgaa agccaaatac agccaaggcg attgtagtga gcaacgtatt
      661 taaaagagcg acaacaaatt gagcttctaa taccaaacca aatgtattga caaacttatc
      721 ggcaaaatag taaatatctt gaaagaacca agaaaattca ctttttaaaa acaatcttga
      781 gaatacaatt gtttttttct tttcaatcat aaaaaagaaa cttaagatga atgacatagc
      841 aaacgccact gccatttttc ctatatcctg taaatagcca agcgcaatcg aagcgccatt
      901 ttgaagctgt tcaaaaaaat cgtttcgctc aatataagta tggatatatt gtaaaacagg
      961 atctgcatct tttggctgat gctcgtaaaa attaataacg gactggatca tgtcaaatgt
     1021 ttgatgaata agcatcggga tatactttgt gaatgccaga tagataaggt aaacgatcag
     1081 tgtataaatc atgatagcta aaacacctgt agggattcgg acaaatcgct gaatgatttg
     1141 aacaagatga atcatcaaat aagtaaagat aaatgtgagc aaaatggttg taatcatact
     1201 tctaactaag aaaagaacaa aaacgacaaa taataaaaca gtgagacggc gtattttttc
     1261 attcgccaaa aaacgctgat aaacggtcaa atcgacaacc tccaaataac aaaaaataaa
     1321 cacgttattc attatatgat ggaatatgaa aataagaaag agcaaaaaga aaaaccgcta
     1381 aatgacgtta tcttatgagt tggttttcct cataaaatcg ttcatctagc agtttcagcc
     1441 ctttttctgg tcttgatgaa aattatctag catttttcgg gtcagatgtt gcagtgtatc
     1501 caattcttcc tgttcaagtg gaagataaga cttgatcttt tgtggaatac cttctgcttg
     1561 tttttgcaac gcagcacctt gagcagtcag cgtaacattt acgattcttt catcacccgt
     1621 ttcacgctga cgattaatat aatttttttc tgctaacttt tttagtaagg gagtcagcgt
     1681 accagaatcc agacacaaat catttcctag ctctttcact gaagtctttt tcttttccca
     1741 taaaactaac atcacaagat actgggtata ggtaagattc agcggcttga ggaggggagt
     1801 gtagtgtcta atgatttctt tagaggcggc atataaagga aaacatactt gattaactaa
     1861 atatagatct tccatttttc cacctccgct gttttactat agtgtatcat agcggattta
     1921 cacaaaaaag tctattcact aactgctttc agagtaactt ctatatttcc agctgtagct
     1981 tttgaatacg gacacacttt atgcgctgcc tctaataatt cttgcgtttc ttccagagaa
     2041 agaccttcga tagatccttc aatctctaca cctaagacaa agctcgtttc actttctgaa
     2101 taaagggaaa cttgtgcact gacagtagaa gccccagaga tatttttttg ctgtttgatc
     2161 aattctaatg cactgttaaa acatgcactg aaaccagctg caaacaattg ttcagggttg
     2221 gttgcatttt cgacgcgttt accaggagct gcaatattca attcgaatgt acgatcggga
     2281 ttatgcactt ctccagagcg tccgcctgtg ttgatcattt tcgtagaata catttttttc
     2341 ataaaattac cacctttaat tatattttat acaattgaat tttacacaat ataattgtgg
     2401 aaagcaaaga aatggattgg cataagataa ataagagaaa gcacatgaaa cagacgcgct
     2461 ttctcgaata gcaaacatat acaaaaaata tcagagacaa aaaataatct catcataaac
     2521 attacatata tttctcaaaa agttgttttc tttcttcaaa aattacttca cgatggacct
     2581 gatgaagcat ccataaataa ccaaaaggat ctctgaacat tgagttagtc acaccaaagt
     2641 ccatcatttc tgtcatttct tgaatctcta cacagccatt tcgtaatgct ttattatgtg
     2701 tgtcctcgat atcagagacg atgatattga accagatcgt atttggatgt tcagcagtag
     2761 gagcagtcaa accaagagac gtgttttcat ccagcatatg gaatctcgta ccatacaagg
     2821 taaaaatgac ttcattattg cctctagggt aatctgttgc ctcaatcagt tgtatttcat
     2881 caaagattgt ttgatacagt tctagtgctt tcaaactatc atttaataca aaatcgattt
     2941 ccgttccttt atgcataaag atctcctctc cttttcagtc gaacagttac tagattcttt
     3001 tattatacca gctaaagaaa acgcattcaa aaaaatagcg gatttactta ccaactcatt
     3061 cgattggatg ataagtaaat ccgcgtccca ttacttctgc tacgctgctg acaatgacaa
     3121 aggcacttgg atcgatttct tctatcaatg gtttcattcg ggaaaattca tgatcagtca
     3181 caacgatcaa taaaacctct tttgactttc gattataccc gccttttgcc tctagcaggg
     3241 taaggccacg tccaatctca gcacttaagc gaaggcggat gtcttccaaa taatgttcac
     3301 tcatgaccat aacagatttc tttcgattga tacctgtttc gatataagtc atgacaattg
     3361 aagtgattgc aatagataaa atagcataaa gaaactcttc tattccaaaa ataaacagat
     3421 taagagaaac aacgaatgcg tctgtaaaaa ataagccaat cgaagtattc aagtggaaat
     3481 attttttaaa aatgagggga gggatcgtcg taccgccgct agaagagttg tttttatata
     3541 aaatcgcaac tcctaaagca aaaatcgcac ttccaaaaat gacagacaac aaccgatctg
     3601 aagtaatcat tgtttctgga actattgcaa tgattaaagg aaaaaccaag cttccgaaaa
     3661 gtactttaaa aaagggtttt ttacctaaaa atagaagagc tagtaccaac ataacgatat
     3721 tcaacactaa aataactata gctcggtcaa agcctaaagc agcttccagt aatattccta
     3781 gaccgctgac acctccagca gcaatatgat gaggccctaa aaacatattg atagcgactc
     3841 ctaatatgaa gagggcaaaa ataatcttaa tgtatgtcca tataaattgt ctcgtttctt
     3901 tcatttattc acttccttaa ttcattaata atactcttat cttattataa cttacttttc
     3961 accttaagtt aactttaatt aataaaaaaa ttaggctagt ctaaattatt atgtttcatt
     4021 cttctagaat atacttctac gccaaaaact gttaaaaaac ttttacttta gaaaattgga
     4081 gaaattgatc gcttaagata aattcaggac actaaatagt acaggaagta gactaaaact
     4141 tttaaaagtt ttaagtctat ctatttggca agtttaaaaa ataaaaattc ggtatcaaaa
     4201 aactgttacc gataacattt ttgaaagcgt tgtcttttgc ttctctatca cttatagtga
     4261 tgacgtcata ttaaaacaca aggaggaaat caatggatac agctgcaatt tatcatcgac
     4321 cggaaagtga atatgcattt ctatatacga atacaagatt tcgtattcgg cttcgtacta
     4381 ggaaaaatga tatcaaaaaa gtatatgtgc tatgtggaga tccatatacc ataacaactg
     4441 aaaaatggta tcaaaaacaa cgaccaatga aaaaatgtct aagtaccaat gttcatgatt
     4501 attgggaaat tgaagtgacg agcgaaacaa gtcgcttaca gtatgcgttc catgttgttg
     4561 gggaagataa cacggactgt ttttacggtg atcaaggaat ttttccttat cgagaaaatg
     4621 tgattactga accaaatttt tattttcgaa taccttattt tcatcaaatc gatcgattca
     4681 ctattccaga atgggtaaaa gaaacagtat ggtatcaaat ttttcccgaa agatttgcaa
     4741 acggggacaa agcaaatgac cccgaacaca ctttaccttg gggaagtaaa gatccagacc
     4801 gagaagactt tttcggggga gatttgcaag gtgtgatgga tcatttggat tacttgacgg
     4861 accttggcat caatggcatc tatttttgtc ccatatttaa agccacatcc aatcataaat
     4921 acgatacgat tgattattat gaggtggatc ccgcttttgg cgataaaaaa cttttaaaaa
     4981 acttgattga tgaagcacat aaaagaggga tacgtatcat gttcgatgct gtattcaatc
     5041 atatgggtgt ccattcacca cagtggcaag acgttctcaa aaacggagaa aaatcgatct
     5101 ataaagactg gttccacatc cgttttttcc cagtagattc ttatcagatg actgacttac
     5161 cagaaactgc tgaaaatatc ccatatgata cttttgcttt tactccattc atgccgaaac
     5221 taaatacagc aaatccagaa gtgcaaaaat atttgctgga tatcgcaact tattggataa
     5281 aagaattcga tattgatgga tggcgtcttg atgttgctaa tgaagtcgat catcattttt
     5341 ggaaaaaatt cagagaagca gttacagaaa tcaaaccaga catctatatc cttggagaga
     5401 tttggcattc ctctcaagct tggctgcaag gggatgaatt ccatgcagtg atgaattatg
     5461 catttacaga ttcgattaaa gattattttg caaaaaagaa aatcacagct tcacaaatgg
     5521 tcagtggaat gaatcatcag caaatgcttt acagagatca ggtgaacgaa ggaacattca
     5581 acttattaga ttctcatgat actgccagga tcttgaccct ttgccaaggt aacaaagaat
     5641 tgatgaagtc tgtgatggcc tttatgtttc ttcaaaaagg gtctccttgt atctattacg
     5701 ggacagaaat agggatgact ggtgaagatg acccggattg ccgcaaatgt atgatatggg
     5761 agaaggagga acaagatcta gagctattcg gttttataaa agaacttgtt tctctaagga
     5821 aacagttgtc taagattatt tctgaaggtt ctactcagtg gctaatagta aatgatcgtg
     5881 aagataagct ctatttcaca cggaaactag agggacagat catctatgtt tactttaatc
     5941 agtcaaaaga accttgggta gtagaacagg aaaatgaggt gattcttagt caaaattgtc
     6001 agttgttaga agacgggaaa gcagagatac gacaatacgg atttttgatc atgtgttgaa
     6061 aactgttacc ggtaacaaca agaaagcgtt tgcaaatgaa gatttgtgcc cattataata
     6121 agggtgtaac agcacgttga atacaaagga ggaaatgaag atgaaaaaaa gaagtgtgaa
     6181 acagttgggt ttagggttaa tctctttagg aatcttaggc ggattagcgg cttgtggcaa
     6241 tggtaactct tcagcagaag gggaagccga tgaaggaaaa acgttaacag tttccgttga
     6301 ttctggatat aaagattata taaacgaaat aaaaaacact ttcgaaaaag aaaacgatgt
     6361 gaaaatcaag ctagtagaaa aggacatgtt cgatcagttg gaatcattag cgttagatgg
     6421 gcctgctgga aagggacctg acgttatgat ggcagcatat gaccggatcg gtgcgttagg
     6481 acagcaagga catctggcgg aagtaaaact gggaaatgaa gcagcttacg atgaaacaga
     6541 caaagcccaa gtgacttatg atggaaaaat ctacggagaa cctgcagtaa tcgagaccct
     6601 tgttttgtac tataacaaag atttagtcga tacagcacca tcaacgttta aagatttgga
     6661 gaatctatcc aaagacagtc gttttgcttt tgagtcagaa gcaggaaaaa atacaggatt
     6721 tttagctaaa tggactgact tttattattc ctatggttta attgcaggtt acggtggcta
     6781 tgtatttggt gatgatggca caaatccttc agatatcggt ttgaataatg caggtgctgt
     6841 agaaggaatc tcttatgcaa cagattggtt caaaaatgtt tggccaaagg gaatgcaaga
     6901 cataaaaagt gcaggagact tcgccagcca gcaattcatg tccaataaaa ctgcagcaat
     6961 cattgacggt ccatggcaag cgcaaacata caaagaaaac aatatcaatt atggtgtagc
     7021 caaaattcct actctaaata atggacagcc ttatcaaccg tttggcggag gaaaaggatg
     7081 ggtagtcagc aattatgcta aaaacaaaga cctctctcaa aaatggcttg attatgtaac
     7141 gaatcaggaa aatcaagaaa aattctttga aatggtaaat gaaatccctg caaaccaaca
     7201 agctagggaa acagcaaagg ctaaaaacga tgaattaaca acagctgtga ttgaacaata
     7261 tgaaacagct caagcgatgc caaacatccc agaaatgggc gaagtttgga caggtgcaga
     7321 aaacttgatg ttcgatgcag catcaggttc aaaaacacca aaagaatccg cagatgaagc
     7381 agtaaaaaca atcagtgaag ccatagaaca aaaatactga ttaaaatgat aaccgtccat
     7441 ttttataaaa aatggaacag gtgcttcaga taaaagtggc aagagcgaga tggaaaatta
     7501 tcttgctctt gttgccatta tcttaaaagc agtttgcggt ttagcaagtt tagagggggc
     7561 attcagatgc agcaagataa aacaagcaat atcaacgaaa aaaaaatcac gctttgttca
     7621 cttattccag ggatggggca gtttgtaaat ggccaagctt ttaaaggtat cgtttttttc
     7681 gccatattcg tcctattcat tggtcagatg cttctgggcg gatttcatgc attggtagga
     7741 ttggttactt tgggaagtat accaatggaa gatcattcat tatttatttt gattgaaggc
     7801 actttgcaat tcatcattac aatcattttc ttgatttttt acggtttgaa tcttttagac
     7861 gcttatcgag tagcgaagat gcgtcaagag ggcaaaaaaa tcaatcggac gatgaaggaa
     7921 gtcatacata atataggtga tgaaggtttt ccttatctat tgacacttcc cgcttatctt
     7981 ctcatgattt ttacgatcat tttcccagtc ctagttacat tgttcactgc atttactaat
     8041 tatgacttca atcatattcc accagccagt ttaattgatt gggtaggggc taaaaacttt
     8101 tttagtatct tctttttaag ctcatatcgt aatacttttt ttgcagtctt ttcgtggacc
     8161 gtgatttgga ctttatgtgc aacaactttg caaatcaccc ttggtattct cacagcggtt
     8221 gttgctcacc agaaatttat taaattcaaa cgtattttcg gtatcatttt cttattacca
     8281 tgggcggtcc cagcttttat tactatcatg agtttttcga atatattcaa cgatagcgta
     8341 ggtgccatca atactcaagt gattcctttc ataaaccagc ttccttttgt agatatcagt
     8401 gcaatctctt ggaaaacgga cccgaactgg acgaaagtag caattatctt agtgcagggc
     8461 tggttaggat ttccctatat ctatgtgatg gttacaggaa tcttacaatc gatttcagaa
     8521 gacttatatg aagcagcaaa aatcgacgga gcaaatgcat ggcagcgctt ttcaaacatc
     8581 acgcttcctg ctgtcttcct agtggcagcg ccaacattta ttacacagta tacggggaat
     8641 ttcaataatt tctccatgat ctatctgttt aacaatggcg gtcccggaag cgtaggcgga
     8701 ggagctggtt ctactgatat tcttatttcc tggatctata aacttacgac tggaacttct
     8761 ccgcagtatt ctatggcttc agcaatcacg ttgattatct ccgtcatcgt tatctgtgtg
     8821 tcattgctgg tatttaaaaa gacaaatgcg ttcaatatgg gggattaaca atgaaaaaat
     8881 ttcattcgag tgctcgattc caaaaacgac tttctcactt ttttacttac ttttttcttt
     8941 taatactgtc agtcattatc atctatccgc ttttgatcac agcaagtact gccttcaagt
     9001 caggaaatat tgcagctttt agtttagatc tttcaagtga ctggacttta ggaaacttta
     9061 ctcggctatt cagtgaaaca ctttacggga cttggtataa aaatacattg atcatttctg
     9121 tcctaacaat gatcgtacaa gtgactgtag taactttggc gggctatact tatagtcgct
     9181 atcgttttat cggccgcaaa tcaagtttga tgttcttttt agtgattcag atggtaccga
     9241 ctatggcagc attgactgcc ttttatgtca tggctttctt attagaagcg ctcgataagt
     9301 actggttctt gacaatgatc tatataggcg gtggaattcc aatgaatact tggctgatga
     9361 aaggatactt tgacactgta ccaatagatt tagatgaatc tgctaaactt gatggggcag
     9421 ggcatttcag gatttttttc cagattgtat taccgcttgt caaaccgatg ctcgccgttc
     9481 aagcattatg ggcttttatg ggaccttttg gggatttcat gttagctaag ttcctgcttc
     9541 gaacacctga aaatcagact gttgctgtcg gcttacaaac atttatttct gatgtgacaa
     9601 accaaagagt ctctcttttt gctgctgggg caattttgat tgcactaccg atttgtctat
     9661 tattcttctt tttacaaaag aactttgtta ccggcctgac atctggcgga acaaaaggat
     9721 aggagcagag tatcatgcaa acatttccgt taaactattt ttccgcatta cgtacgccaa
     9781 ctcaagtgtt tgcgggacgc aaactattat catggcctaa atttttcttg atatttgtat
     9841 ttttagtttc cttgatggtc atgcctgtga ctctttttta tgccaatcag atccaagcga
     9901 ttccattaga acaatttcta tccgttcatt cgctgatcga tgaacaagga acccaaaaat
     9961 tttctgaact tgaattatct gaaactgggt tacaagcatc gcaacaaacg atagctgtga
    10021 cccctgaaat tttggtaggt gtgtctttat ctgagaaaca acaatccgat catggaactt
    10081 ttattgattt tgagaaggaa caatgggtga tccaacaaaa ggataaatct ggtatacgcc
    10141 gctatacgat gaattatagc ccatctttcc aaccagattc tgtacgtacg cccgaagatt
    10201 tccaacgatt tttagaaaga gaattttatg ccagtaatcg tccaacaatc attttatctt
    10261 atagtttaag tcttggtctt gtcctatttg tcatgacgag tctcatttta ttcggggctt
    10321 cctttttctt gtggatgaca agaaaaagcc aactttcatc cattcataca ttcaaagaga
    10381 gtgcaaattt gatgctgaat gttatgggaa taggttccat ggcagcagca gttgtagggt
    10441 ttatccactt tgactttatc ttgatgctaa gtgtccaaac aacgataact gtcttgctgc
    10501 ttttatgggt ttttgtcaaa acaagattca aagataagcg tgtcgaatga caagtttaag
    10561 cgatttatgc gacaatgaat gtgaaaaaaa tgaaaaataa agtagttttt gaaaaatttc
    10621 tgaaaaaatt aaacttctta gttgattctt ttctttttta gtattaacgt aatagggtag
    10681 tttttttaag gaggaaaatc atgttagaga aaactttata caatcaatta ttttcacgtt
    10741 ctttctcgct ccctgtcgaa gtaaattatt gggacggtac aacgaaacaa tacggagata
    10801 cggacactcc tccccaaatc aaaatcaata tccatgaaga aatcccaatg aaagagatta
    10861 caagtaacgc ttctttggca ctaggagaag cctatatgga tcatcgaatc gagatcgagg
    10921 gaagtatcca agcattgatc aacgatgctt atcagcaagc aaacagcttt ttacgaggaa
    10981 aagattatct aaaatggctg ccaaagaaag aaaaacatac gaaacaaaaa aacaaagaag
    11041 atatccatgc gcattatgac ttaggtaacg acttttataa actttggcta gatccaactt
    11101 tgacttattc ttgtgcttat ttcaatacac ctgaagatac gttggaacaa gcacaaatca
    11161 ataaagtcca tcatatctta gacaaactct ttatcaaaga aggcgaaacg ttgcttgata
    11221 tcggttgtgg ctggggaaca ttgatgttca ctgctaccaa agagtataat gtcaaggcaa
    11281 ctgggatcac actaagtgaa gaacaatacg atttgattac caaaagaata aaagaagaac
    11341 atttagaaga taaatgccgt gtattattaa tggattaccg cgaactaaaa ggcgaaacgt
    11401 ttgatcatat cacaagtgta ggtatgttcg aacatgtagg ttctgaaaat cttgaaggtt
    11461 atttcaaagt ggtaaaagat ttattgaaac caaaaggaac agctttgatc catggaatca
    11521 gccgacaaca aggcggtgcg acaaatgctt ggatcaataa atatattttc cctggcggtt
    11581 atgtccctgg tgttactgaa ttagttgata atattacaaa aaacgatttg caactgattg
    11641 atttggaaag cttacgtcgt gactaccaat tgacattaga acattggaca aagaattttc
    11701 atcaagtcca agatcaagtc acgaaagaaa tgggtgattc cttctatcga atgtgggatc
    11761 tatatttaca agcttgtgca gcttcatttg aatcaagtaa tatcgatgtg attcaatatt
    11821 tgcttgttca acctggaaac aatgacatcc caatgcatcg tgcataattg aggcaaaagt
    11881 actgtttaaa gactatttaa aaagaagcta agttttatga tgctccagaa gtgaactttt
    11941 ttgtctaact tctaggattg tctctaaagc ttagtttctt tttctttata ttttcataat
    12001 aaaagtttgg ttctttaatt tttaaacatg acagaaaatt ttttcttcgt tatacttgta
    12061 atagaatact attttataac aaaggggatc gaatcaatga aaaaaactgt tatttatact
    12121 agtttatttg cagctttgtt tttagctgct tgtcaatcaa ataccaatca aggcacatct
    12181 gggaatacgt cttccagtag cgaacagcgc tcttcacagg tatcggactc ctcaacaaaa
    12241 gcaagcacat cttcgtctag ccagacaaaa agttctagtg aagcaagtac tcagtcagat
    12301 atcaaagtgt ctgcagctcg tgcgatcgaa ttgttccaag ataaataccc agatactgca
    12361 attactagtt tggaattaga tagtgattgg ggatcttact tctacaagat agaaggtgtc
    12421 gatgatcaaa aagaatacga agcaagaatt gatgctcaaa atgaaaaaat ggagacagag
    12481 aatccagaaa ctctagatcg agatgaacaa aatggtcaaa agaaaaaaga agatggtctg
    12541 gatgttgata aattgatcac gattgaggaa gcagcaaaaa tcgccgtcga caaagtagga
    12601 agcggtacgg caacagattg ggatttggat aaagatttag gtactactta ttgggaagtc
    12661 aaagtaaaag acggcaatca aagtacatca gtcaagatca atagccaaac aggcgaagta
    12721 ctgtcaactg aacaagatga ttaagaattt cttcggaaaa caagagttga tttttctttt
    12781 agtcatgata cactagacaa aataacttgt ttgaaggagc gatttacttg agtttagaaa
    12841 cgacctttgc caatcatatc tttgccaatc ctttgatgaa tgcatctggt gtccactgca
    12901 tgactaccca ggaattagat gaactggctc attcagaagc aggagcattt atcactaaga
    12961 gctgtacgat caatgaacga aaaggaaatc ccgaaccacg ctattttgat gttcctttag
    13021 ggagtatcaa ttctatggga cttccaaact taggtttttc ttattatcta gagtatgctc
    13081 ttgcgtatga aaaagtgcag gaaaaccaaa atcaaccgtt atttttttcc attgccggga
    13141 tgagtgtcca ggaaaacttg gaaatgcttg agaaaataga aaaaagtggg tttaatggga
    13201 tcactgaatt aaatttatct tgtcccaatg tgcctggaaa accacaacta gcttacgatt
    13261 ttgaggccac ttatgaaaca ctgaaagaag tattcagcat cttttctaag ccgctaggaa
    13321 tcaaattgcc tccttatttt gattttgctc attttgatca gatggctgat atcttgaatc
    13381 agtttccatt gacctatgtc aatgctatca acagtgtggg caatggtttg tatatcgata
    13441 cagaacaaga agcagtagtc atcaaaccaa aagaagggtt cggcggcatt ggcggagagt
    13501 atatcaagcc gactgctttg gcgaatgttc gcgcttttta tacacgtttg aaaccagaaa
    13561 tccaaatcat tggtacaggt gggattcgga caggacaaga tgcatttgaa catctgctat
    13621 gtggcgcaag catgttacag attggtaccg agcttcataa agaagggccg gaaatttttt
    13681 ctagaatcat aaaagaatta acgcagatta tgtcagaaaa aggatatacg tcaattgacg
    13741 aatttaaagg caaattacgc accatttcat agcaaagaga cgaaggtcat gattgatctt
    13801 cgtctttttt tataaaaaac actcgtctgt tcattcctgt gcaagcgtac tcattgtatg
    13861 ttagacgaac ttgtgggaaa ataacagagg caaaaaggag gataatatga atgatgcaac
    13921 agaattagca aaagagctta aagaaaaaga atttagtttt caagaactag ttacggatat
    13981 acagaaaaaa ataaagaagc aaaatcatga attgaatgcg tttgtcgcgc ttgaaccatt
    14041 cgagagtaat tcccacgagc tattgattcc ccagtcagaa aaagggccat tggctggtat
    14101 cccatttcct ttaaaaatgc tcggtcaaga aaaaaaggga tggctagcta cttcaggatc
    14161 tcgtttattt gaaacacacc gagcttctca tacatctaat tatgtgcggc aagcagaagc
    14221 gataggtcta gttccttttg gacaaaccaa tgcgccagag tttggtttca aaaatattac
    14281 agacccagtc atctatggcc cagcaagaaa cccttggaac cttgaatgta caccgggcgg
    14341 atcaagtgga ggagctgctg ctgcagtttc atcaggaatc gttcctttag ctggtgctag
    14401 tgatggcggt ggttctatta gaatacccgc ttcgttttgc ggattgattg ggctgaaacc
    14461 ttcgcgaggg acgatgccag ttggtccata tgcttggaga ggatggcaag gagctgctat
    14521 tgatttcggc ttgacagttt ctatgagaga cacggaggct ttattttatg ggatgagaag
    14581 tatccattcc ggtgcgccat atcaagtatc gccagttgag tggcaaacac atccaagaaa
    14641 aaaacggttg aagatagctt tttgtgttga ttcaccgatc cactcacaga ttagtgaaga
    14701 ggcagtactt gctgtaaaaa aagctgtaga tttccttgga aaagaagggc atgatttgac
    14761 agagattcct tacccactag atggtcgtaa actgatcacg tcttattatc agatgaatgg
    14821 cgcagaaaca gcagcaatga tccgctcgat tgaaacaggc atccagcgag ctgtcagaaa
    14881 agaagaactt gaacccattt cttggacttt gttccaatat ggtcagaagc tctctgccgc
    14941 tacttacatc gattctctgc atgtatggga tgaagcagca attgtcatgg aaaacctaca
    15001 tcaagaatac gatctattcc tttcaccaac gactgcattt accgccccta aaatcagcga
    15061 agatttgcaa agtgatgcga taagagcaca gatggaacac atcagtgatt gttctgaagt
    15121 agaaggttta gacgttgttt cttccatgtt tgaggagagc ttgaagatca caccttatac
    15181 acagttggct aatctgactg gacaaccagc aatcagcttg cctactcatt tgacaaaaga
    15241 aaacatgcct ctaggaatcc aatttatggc tgccagagga agagaagatt tgctatttca
    15301 aatcggctat ctatttgaag caaatcatca gttccattta ccaaatccat ggaaatagca
    15361 gaaacaagga gaagaagaat gaagaaaaaa agattgtttg ctctaataac tagtgccttt
    15421 tttattttaa gcgcttgcgg tacagctgcc gctaatcagg aagataacag ctggagtaat
    15481 gtagaaaaaa agaaagaatt agtagtagcg acttctggca cactgtttcc cgcatcttat
    15541 tataatgatc aaaatgaatt agttggttat gatgtagatt tggcaaaaga ggtggctaaa
    15601 cggttaaatg tcaaaatctc ctttaaagaa tacaacgtgg atggacaaat cacttctgtt
    15661 tcaaaaagag aatcagattt tgctgcgaac gattttggta tcacaaaaga aagagaaaaa
    15721 aaattctccc tttcagagac tttcaaatat tcatttgaca gtatgatcgt acgaaaaaaa
    15781 gatgattcag gaatccactc acttgaagat cttaaaggga aaaaagcagc tggcgaaccc
    15841 aatactagct atatgcgttt agcggaaaaa cacggagcta aattagtcac atatgacaat
    15901 gccacgaatg atcagtattt aagcgatgta gcaaatggtc gaacagatgt tattctaaat
    15961 gattattatc tgcagaaaat ggccgtatct gctttaccag atatccctgt aaaaatactg
    16021 gagaacgttt atttcaatga aaacgaaagt ggttttttat tgaaagaagg aaatgatgct
    16081 ctgaaaaaga aaatcgatgg cgtattaaaa gagatgaaag aagatgggac gacaaagaaa
    16141 atatctgaaa aatattttca aactgatgtt tcagtcaaac cgaaagaaac gatggctgag
    16201 tcggtgagtg agtgatgtac tttcctctaa ttgatttttc cctcatgtgg acttcacttc
    16261 ctttcgtact gcaaggcttg gtatacacat tagggattgg cttcgtgtcg tttcttttag
    16321 gaaatctggt agggttgctt ttgacagttt taggtctttt ggattggctg cctctgaatg
    16381 tatttattcg tttttattta tcgttcttta gaggcattcc cgcactagtc ctgctgtttc
    16441 tgttatattt tgggttacct tatcaattaa gtgccttaac ggcttcagtc atctgcttta
    16501 cgattaccag cagtgcattt attggtgaaa tctatcgagg atcactagca ggcgtttctt
    16561 caggtcagtg ggacgctggt ttagcttctg gtttttcttt ctttggggta ttgaaatata
    16621 tcgttttgcc gcaagctttt cgaatctcag taccggcact cagtaacgta gctatggatc
    16681 tagtgaaagg tacttcgtta gcagcaacaa tcacagtgcc agaaatattt caaaaagcaa
    16741 agatcatagg cggtcggaca ttcgattatt tttctctcta tattttagtt gcactgattt
    16801 attgggtcat ttgtatcggg atcgaaaaag tgcaacagta tttagaaaaa cgttctatgc
    16861 atcagtcaat ctgaaaaata gaaatggtgc tagcgtggct ggcaccattt ctattttttg
    16921 tttcttgtat attctgccta gtattttaaa accatttcat gtaaaatgta aatcgaaaat
    16981 atgttcggag gtagaaaaca tgaagacccc gctaaccatc gaaatagaat cctcgttata
    17041 ccaatattgc atcgagcaag gcggcttggt tgtagaagaa gtcacgatgc ctgatgacca
    17101 aggaattgta gatacgctta gctgcttgac aaaatttgat ggaagccgag aatggcgatg
    17161 ctatgagctg aaagtgacaa aagcagattt tcgctctaca gccaaactgt catttgttgg
    17221 acattataat tattttgttt taccaagtaa actatatgaa gaagtaaaaa ctgaaatccc
    17281 tacaggaata ggtgttttag tgtatcgtcc gtacacggtt gaagaggaga tgcctgcctc
    17341 tggtacattt ctgattgcga aaaaagcagc aaagaaagag cttgctgtac cggaagaagc
    17401 tttgacaaac cgcttcatgg cttctttatt cagggaagta agaaaagcaa agcaaatgga
    17461 gcgaggcgta aaatattttc caacagatca attgtacaaa gaattgaaaa gacgttcaga
    17521 aaatcaagat ccattttcta acgaacgata ttatgaacgg tttttagagg aaatagctag
    17581 tcaggcaatc aatgagttgc aagaagaagt tatcgcgctt cagcatgatt atgaatattt
    17641 gaggcaacaa cagcagatcc gtcggttgcc tacagagcca ttggagtgaa aaatatgtac
    17701 tatccttatt taagaggaaa acaatttgac ctattagcat taaaagaagc actgtcgcga
    17761 ggattgctct ccaataaaat ccaaccagtg atcgaaccag tacgtgattc cgctacgctt
    17821 aaaaatgtga tcgaattatt tcaaaaaaag caccatccaa tcgctgtgat ccaaaatccc
    17881 caagtaggac aattcaaatt attcgatcag catgtgcaca gttggacagt caaagaaaat
    17941 agctctgtcg tccctgcaca gatcttaacg ccagaaaatc tcagtgaagt actggattca
    18001 cctccagcgt ttcttgtttt cgatggacag cactacccaa aagatacaga ggtgtggaaa
    18061 cagttggcag gagttgattc gaaatttttg ataccagata ctagtcgctt tcgcatctgg
    18121 ctgcccgaaa acaaaattgt gatccgtgac tcttttcaaa cgagaaagca tgttgaaagt
    18181 tatgcagata aaacagatga cttttttagt gatgactatc tttttttcca cgcagacgga
    18241 tatattggat tttctgattt cacgatcgaa ggtagccgtt atttcgataa agggttccct
    18301 agccgagcgc ttgctatcca tctaacgtat attgatgctt acggcaatat acgcgtgaaa
    18361 cattttgtct ctgacagtaa cgactctgct aaagaccaag cattgaagtt tcttgaagca
    18421 ggagataaaa tgaaaaaatg gatcatgcgt caccatcatc aactcttgat tacttcagga
    18481 atgattgaat tattggctct ttaccagcaa caaaaattcc ctggactggg agtgttgaaa
    18541 aagtggtcac ttatgcatca tttggaactt attagtcacc tgctagatca tccaaaagat
    18601 tggcttaaat attattcaaa agttcaggaa ctatatgaag tgatccaatg attagataat
    18661 gtaaatgaaa aaggaataga aaagaggaaa ctggatgtat attcggcaaa caaggaaaga
    18721 agaagtagaa gaagtggtag aaatcattaa tgccgcagcg gatttcattg cttcgcaagg
    18781 ctctcctcaa tggcaaaacg ggcagaaacc aacaaaagaa acgattttga acgatattga
    18841 aagaaaagaa agctatgtat taatagtgga agatcaaatt gctggaacag ctgcattagt
    18901 ctcaagcgtg gatcccgttt acacaaaaat agatggtagt tggaaagaat caactggtcc
    18961 ttatttatcg attcatcgtg tcgctttagc agaaagtact cgaggaaaaa aactagcaaa
    19021 accgttctta gaacatttgt tgacgattgc agccagcaaa aatatccaag atatccgtat
    19081 cgatacttat ccagctaatg aaccgatgga aaagaccatc tattctgctg gattcactta
    19141 tcaagggatg attgaatttc cttttgaaca cggcgaaaga aaagcatatc aaataatcat
    19201 caattgacta taaaatcatc tgagcaaaga taaagacatt aacactactg aaaaaaacaa
    19261 tcatatgata gccaagaggt tgtaacagaa gtggccagct tcaaaaaaca agaaagaatt
    19321 tccgaaaatg cttctcaaat ttttgtggaa ttttagcgta ttttacgaaa tagctgcttt
    19381 ctgaaactcc cttcatcgag aggtcgtgac atagcttttg tcacgacctc tcggcttatc
    19441 ctacgagtat tattcgatac atttatatca ataatccttt ttttatttta tctgcagctt
    19501 cttggaacgc tccatcgttt gacacgacta aaagtgaggg gatagctttc aaacgtttca
    19561 actgtgctaa atcttctaca taaaccgcca gtctggctga aatctgttca gatgaatctc
    19621 cacgtttttt caggcgcgat tgcaatgttt ctttagagat cgtaataaag ataggacgga
    19681 ctaccgtccc gaaatactca tataaatgcc aaaaaccatt tgctgtcaaa acggcgtaac
    19741 aatttcctac tgtcagtttc tttttaattt ctgctttact ggaaccatat ttatgttgag
    19801 catattggtc ccactctgca aactcatttc ccttgatcat ctgattgaat gtattgtcag
    19861 aaacaaaata ataatcctct tgatcttttt ccccaggtct tggtgatcga ttcgtgtaag
    19921 taatgatctt ttgttccggc tgaaaaatag cttctgcgag tgaagttttt ccagaaccag
    19981 aaggaccgat aaatacatag caataattca ttgtcatttc tcctttgatg attgaacaag
    20041 tgaaaaagct ttggaaaata tttccaaagc ttttaaaagt aactttgctt ttttgtatat
    20101 tataccagca agccagtcac aatagcactt aaaaagctga ctaaagtcgc tgttagcaaa
    20161 attttcaatc cgtgttttgc gacaagattt cctttttctt catttaatcc cttcatcgca
    20221 ccagaaatga tcccgataga agagaagttg gcaaatgaaa cgaggaagac agatataatt
    20281 gctgttgtac gctcagtaaa atggaaatta ccatttgcta attctgtcat agcaacaaat
    20341 tcatttgtaa ccagtttagt cgccatgata ctaccggcat ccactgcttc tttccatggg
    20401 attccgctga tgaaggcaag aggggcaaag atgtaaccta ggatctcttg gaaagtgatg
    20461 ccgaatatcc cgtggaagat agcattgatc atggcaatca aagcaacaaa accgataagc
    20521 atagcagcaa ccgtgatcgc cacatggaaa ccatcaagaa tgtattctcc caacatttgg
    20581 aaaaatgtct gttctttgtt ttcttcaatg atcagctcat cttctttttc ttctaataca
    20641 tagggattta caattgaagc cagaatataa ccgccaaata agttcaaaac aagggcagtg
    20701 atcacatatt tagaatcgat cagtgccata taagatccga cgatcgacat agaaactgta
    20761 gacatagccg atacactcat ggtgaacaaa cgtttctcag ataggaaggg taattccttt
    20821 tttatggaaa taaaaacttc cgattgtcct aaaatagcag aagctactcc attataagat
    20881 tccaatttgc ccatcccgtt gattttactt aatcctagac caacagcttt cataaataat
    20941 ggaagaatct tgatatagcg tagaataccg ataatagcag aaataaatac aattggcatc
    21001 aatacggaaa gaaagaaagg tgcacttcct ttatttgcta caccggcaaa aacaaagtca
    21061 acaccttgcc cagcaaaagc aagaagatga tcaaacattt ttgccaatac agaaacaacc
    21121 gctgtaccaa aagttgtacg taataatacg aaaccaagaa caagctgtaa aacgaacatc
    21181 acaattagtg gtttcaattt gattgctttt ttgttactgc tgatcaaaaa agcaagccct
    21241 aatgtgacaa ataaaccaat aatacctaat aaataactca aataatcact cctattccaa
    21301 attccgtttt attttacctg ttttgcaaat aaaatactaa tctttagtga aattttcatt
    21361 acttttttag agtgaaacgc attcattttc cattagaaaa taaagcgaac aaaataaaag
    21421 gtttaaaaag tgtaacgtct tagtaaagtc tataaaaaaa cgaaactatc gattaagcta
    21481 atagtttcgt tttcaacatt tataagtaaa ctttttctat tggtaatata gattttcgga
    21541 agggtagaca ggtgcgcagg taatatcgat tcctagtttt ttcaatgttt gttcatcatt
    21601 tttattgacc atcacagtag agtgggcttg tgctccctca agttcagcta gtttatcata
    21661 agcaacttga gcgattggat tcgttactgc actgattgat aaagcgatca agacttcatt
    21721 gatgcttagt gcatccaaag aggaatgaag tgtctttgat ttcaatcctt gtattgtttc
    21781 aagaactaat ggtgacaata aaggaatgtc atctgcgata tgggctaaat gttttactgc
    21841 atttaagata actgccgctg acgcatccat caatgaactt gtacgcccgg taatgatgac
    21901 ttcatctggt aattcgattg caatcacagc agaaggatct tttgtaggac tttgcgcttg
    21961 aatcttatct gcatagtcat gggcagggac taccacgttt cggtcttcag gacgtaaacc
    22021 gacttcttcc ataatcagtt tgattcgatt aactgcttct tcgtcgatca atcctttttt
    22081 gaagtcgcat tctgtttgga aataacgacg gatgatttct tgtttagagg cttcttggac
    22141 aacggtatca tccacgatcc caaatcctac acgattcaca cccatgtcag taggagattg
    22201 ataaacagat tctttaccag taattttttc aataatacgt ttgattacag gaaatgtctc
    22261 aacatcccga ttatagttca cagctacttt attgtaggca tcaaagtgga aggaatcgat
    22321 catattgaca tcttttagat cgactgtggc tgcttcataa gcaatgttca gcggatgttt
    22381 caacggaaca ttccatactg ggaaagtttc gaacttggag taaccagctg catgtccttt
    22441 ttggctttca tgatacagtt ggttcaagga agtagcgagc tttccacttc ctgggccagg
    22501 agctgtcact acaacgattg gtttagttgt ttcaatatac tcattttttc caaaaccatc
    22561 ttctgagacg attttttcta cgttgactgg atagtcttcg atttctgagt gtttatagac
    22621 cttgatgttt cgtctttcta gtttattgat aaagactttc gtggcaggct gtccactata
    22681 gcgagtgata acgacactgt tgattaataa gccataacca cgtaattcat cgattaaccg
    22741 caagatatcc atatcataag taatcccata atcaccacgg atcttattac gttcaatatc
    22801 tccagcatag acgcaaatca gtatttcagc ttgatctttc aatttttgca gcaatttgat
    22861 tttcgcatct tcttcaaatc ctggaagtac acgtttcgca tgcttgtcgt caactagctt
    22921 cccaccaaat tctaaatata atttgtcata gtggttcact cgttccaaaa tatacgctga
    22981 ctgctcttca atatattttt ctgaatcaaa accaattttt ttcactaggt tccctcctta
    23041 agtactaaag cattttttca tttttttgag gattcgtcaa ctggaagagc gaaattcctc
    23101 aaaaaaacaa agaaaatggt ttaaaccaac ttgtctagat agttattcat tggtatgata
    23161 gtttttgata aggaaggtgc tacatgaaaa aaagacagaa aaagaaaaac gcatataaac
    23221 actatatccg ttcgattttt accggttatg aaagaatgct tgaagatccc gaattggaac
    23281 aattgacgtt tacttatcta aacgaagaaa cgcagctaac tcgtgatgag catcagcgca
    23341 ttcatttcac aacaagagat ctgcctagta aataaaaaat aagataaagg tcatcggatt
    23401 cgattctgtc ctatcagatg gaaagactag ttgatcgaaa aaaaggctgt accaaatttt
    23461 ggtgcagcct gttttatgga gcattgcccg ctctttttta taacaatttt ttacagaaaa
    23521 tggtactatt gaagtattaa taagtgaaaa acagatgagt aagaggaggc aagtagtatg
    23581 aaagagccag atacaaatgc aaattatgag ccagacgaac tagaggagac gaatgcggat
    23641 caggatacag gacaagaatc gtcttctttt tacgatatca aagaaaaagc aagcatgaat
    23701 ctttcccaat tattagaaga cttacaggct tttgaaaaag ctgtccgcga agaagatatc
    23761 cctgagatct accgtttata caatggccga ttgaatgaag aattaaaaag aagctcaaat
    23821 gaaaatcacg agatcgatca attgctgatg cgtaagatcc atgatcgttt tttacaggaa
    23881 tttcctttta tggaacaagt agaaaacatc tcgccaacga tgagctatta caaaatcggc
    23941 acttattacc atgatcggcc cacggtcggt attgatgcaa gtctgccaga aatttttgtt
    24001 ttgcctaaga tcgatgaaga gtgggagaaa tattcccaac cggagtcaac ggactatgac
    24061 aaaaaaatca atgagctaga cgcaaaggtg atcactgctc agacagaaat tgaacgttta
    24121 gatgaacaaa taaaagaaat caatcgacaa atgactgatt tgaacgacaa taaaggattc
    24181 ttgaatcgta aaaaaatcga ggaagaaatt caagaattag agaagaagaa gcaagtacta
    24241 tctaatgaaa aattaggctg gcttccttat attgagacgc ctgaaacaat ccagcagcaa
    24301 aaagaagcat tgaagcaaga agcaagagca gaccagcttc gtgcagccat cgtagaaaaa
    24361 gaacaaaggc aaatcagacg ctatttcggt agcaaagagg gattcggtca agcaatccat
    24421 gaattcttga tgaattatct tggcaatgag aatcctaata atcaatctaa tgaaggaggt
    24481 tccgagtatg aatgaacacg atgaagcaga atggacaaaa aatgaagaac aaacagaaga
    24541 tcatgaagaa acgaacactt cattggaaga acaaacaagt aatcctctgg atgacacaga
    24601 agaaatccct atgctagagg aaacaaaaat acacgaaaaa gaaaaagtaa ctccgacgaa
    24661 tacgaatact gcagaaaaca cccatgctta cgaaataact gaaaatcccg ggtatttaga
    24721 aggaaaagag caagatcatc aagatatcgt cagtttgatt gaaacagcgg aagcagaatt
    24781 agcggattta cgtatgagaa aagatttgat cgaatcagat tttccacaat tattagaatc
    24841 atatgatcgt tttatattga atgaagaacc aatctccacg atcggaaaga caagcctgat
    24901 cgaatacttc acgtatgaat tactgaaacc gttgaatgat attggtctgg aacggtcaaa
    24961 ttcagcttat gacacatgga aaacaagaca tttttcgatc aattatacgt tgaatggaca
    25021 aaacgaatta gtcttttcct ttgtattacc gaccatcgat caacgatacc aagtggaatc
    25081 gatgagtctc ctaaacgtat caccagagac aatggaaatc aatgtccaag atgaccgggt
    25141 gctttctttg atccgacact ggtcagtgga tcgagtattc tctgcagggc agatcacgat
    25201 attcaatcac aaattgaatc aattattagc ccatgcaaga acacttggtt ttaccgttaa
    25261 tcagacatta ctagacaata cgaagccact tcgtttgaat cttcagagcg aatttgaatt
    25321 gacgaatgaa gtattggatg atatttttat cgtggcaatg aaaaatccat cctacgatat
    25381 ggaaaagatc aacgaaacta cttatcaagt acgattagat aaaggacagt ctttaacgat
    25441 aacaacaaac gaaaaagatc aaacagtctt gtcgatctca tctggagact acccacgatc
    25501 tgtcattgat ttctttatca attacgaatt cttggtccca ttaatggtga gaaagtcctg
    25561 attggataag ttggattacc agatgtcatt cagataattc tgttccaaag gacttgcggc
    25621 agttatccag aataattgtc acaagtcttt tctgtatgta ctaaatggac gtgaataact
    25681 tgctgatgaa ggagggattt cattaggaat gtccacaaat aaaatagcac agcttagctt
    25741 attgtctgct gcttgtgtag caggtaggat cgcttttcaa tttattccga atttccagcc
    25801 aatgactgct atttttttat ttatagtact ttacttaagc ttaaaagatg cgttaattgt
    25861 catgagtctt tctattgcga tcagcagttt ttattttggt gttggaccat gggtcatcgg
    25921 ccaatggatc agctatactg ttgttctgag tttgttttca atcgtctgct tgagaaaaac
    25981 agtgcaaagg aatctatggt taaagggagt ctgttttttt ctggcgggca tggtttacgg
    26041 aataggtatg accgtttttg atacgctgtt atatcgtttg cctcaacctt ggatctatta
    26101 ccttcaaggg gtgtcgtttg atttgatgca cagtataggc aatgttgtgt tctttcttgt
    26161 ttttctgcca gtcgtcaaac gtttttacaa tcattcagga ggaaaaaatg aaaaaaataa
    26221 tttatagttt gcttgcaatg agtgtcagta tactcatttt gacaagttgc agtacaacct
    26281 atacacaatc ggcttccaac caaaaggagg aagtaaaaac atcgcaaaaa gcaacaatca
    26341 cgttacaaga aaatggtcaa aacttttcgg aaaaagaagt gttcttcaaa aaaggcgatg
    26401 atttactgag tattttgaaa cgaaattttg aagtcaaaga agataacggc ttcatcactt
    26461 cgcttgaagg gcactcacag gatgagaaaa atcaactcta ttggatgttt actgtggacg
    26521 ggaaaagtgc tactactggt gccaaagaga tcaaattgaa tgatggacaa tcggtcattt
    26581 tcaatttgtc taaactataa gtttcataaa aaactgttaa agggcgaata ttgccataat
    26641 tcagtgagtt cagttgatga aagaaggaaa ataacatgga aaattttaaa aaaagcggaa
    26701 tgttttccgt aattgctgct ctaggggcta atattctagt tgctatcagc aaatttgtcg
    26761 gctatgcaat cagtggcagt gccgccatgc taaacgaaag catccacagt atcgttgatt
    26821 gcagcaatca gattttgctg ttattcggtg ataaacaagc caataaagga cagagcgagt
    26881 tgcatcaatt tggtgaagga cgagcaaaat actttttcag tacaatcgtc gcaatgatgc
    26941 ttttcttcgg cggtggggca cttggggtga tggaagcttt tgaaaagttg acgcatccat
    27001 cccatgaagt gggtaatccg atcattgtta tagcaatact gttatttggt ttggtaatcg
    27061 aaggaagttc gttacgcgtg gcaatgaaag aaatcaaaga attgaatact gaaaaacttt
    27121 ccacgatgcg ctttttgcgc gaaagtcgac acagtgaaat actgattatt tttacggaag
    27181 acttgtgtgc tgtaatcggt ttggtcttgg ctttagcagg aacaatattg acttatgcaa
    27241 ccgggattgc tgcatttgat gcgatcagcg gattgctgat cggtttcttg ctgatgggag
    27301 ccgccatttt cctagcaaaa gaattttata gtctgatcat cggtgaaagc gtgacagcaa
    27361 gcgatttatc aaaaatcaag ttagcttttg aacgtcctga gatcagtcgg ctgatcgata
    27421 taaaaacagt tcatttaagt ccaacggaga ttttagttgc agcaaaagca gatatcgttg
    27481 gtaacaaaga gaatgaagct tactcggtca tcaatgatat tgaaaaaaat atgcgtcagt
    27541 ctcttcctga caagaagatg tatatataca ttgaaacaga taaatatgac ccaaattatt
    27601 ctcgtaaata aaacgtttat tcatgaattg aagcaaaaat gagaaaaata taatcttgtt
    27661 tttaaataaa acggctacaa tttagcgaat ttatgttaca atgagtccgc tgtttatttg
    27721 ttgtaattaa aggagatatt ttaatgaaca aaaagaaaag tgcgccatgg cttcaagctt
    27781 tgcatgcagt gatgccactt tgtataagct atataccagt aggattagct tgcggagtat
    27841 tgttgcaaaa agttggattt gatcctctct tatcaggact gttatcgatt ctggtctttt
    27901 ccggtggcgc gcagttttta gttgcatcta tgcttacgac gcaagcatca tttgcaacga
    27961 cattattgat ggttttcttt ttagaattac gctatacatt attaggagca agtcttgccg
    28021 gttttatgaa aaaagaaaag cggacgtttt tggctgtctt ttctcaatca ctgaatgatg
    28081 aaaactatgc ggtgaactac ttaaagtttt caactgaccc ttcctggaat aaaagaaagg
    28141 ctttatatgt caattggttc tcaatgactg catgggccgg tagcaatatg atcggtaatt
    28201 ttttcggctc ggtgattcga gtagatgctg accttgtcca ttttgctttg acggccatgt
    28261 tcattttcat gtttatcatg cagatgaaaa gcgcactact gatctttaca ggtttattct
    28321 caggcgtatt aggggtcgta ttcatggtat tattccaaaa tactttcgga ttgattgcag
    28381 caacagtcat tgcttcattt gccggattta tgctggagaa ggcattcaaa aaagaaaaag
    28441 ctaagaaact aagagaccgc ggtaaagatg tcaatgagcc gctcttcaac ttcccggaac
    28501 aggaggccaa tcaccatgac taaactatat ttgctacttt tagttgcttg tctgttcatc
    28561 gtggcatata tcccgcgctt gttcccgatg ctttatttta ctcatcgaaa agtgccatcc
    28621 tggttcagtg actggatgaa atatgtaccg gtggcattat ttgcggcgtt agcttttaaa
    28681 gatgttttca ttactcatga acatctggat attgcttgga atatcaaaat agctgcaatg
    28741 attctagtag caggcgtggc ttacaaaaca cgttcgatgg cgttgtcagt tttgacagga
    28801 cttgcgtctg tctttttgct gtctatgctt taaactgttt tattttatta aaaacagaga
    28861 ttgcgacata agttgttcaa actgatctat ccgaactgca tttgcaacag tcaattctgg
    28921 atgcaagttt attcgtaggg ataaaaaaga ttagtgttgg cttatgatgc aagctctttt
    28981 ttattttagg aattagagag ggatttgtcc ttctatgatt ttttgctata atagggaaga
    29041 tgtttatttt atgaaagaat agttgaggga atttaaatga ataaaaaatt gatgcaagga
    29101 acattttggc taacctttgc taatcttcta tgtaaagttt taggggtagt ctatttgatt
    29161 ccctggctaa gtatgatggg gaacaatcaa gatggtatgc ttgctacgac attgtataat
    29221 gttggctatc ttccttatgg attgttcctg atgcttggta cagtcggatt tccaaatgcg
    29281 attgcaaaaa aagtagctgt agccacaaaa gaaggagata acgctgcttg tcggctgatt
    29341 tttagaagta cgatcaatat catgtttgtc atcggtatcg cctctgctgc actgatgtat
    29401 ttatttgctc ctttactagc cggaatcagt ccgattgcta acgttaataa tgggatacta
    29461 gctatcagaa gtttatgccc atctttgatt gctatcccaa ttcttagtgc aatgagagga
    29521 tatttccaag gaaaaaatga tctgcggcct tatggaactt ctttgattat cgaacaggct
    29581 gtgcgagtga tcgttatctt ggctggtact tattacttgc gcgtattgac tgacggaacc
    29641 atattagaag ctgtattgat cagtacagtc gcttctttct tcggtgggtt agctgcgatt
    29701 atccatatgt atatcgtcgg acgcagaaaa gacttcttcg aacttaaaga ttttttgatt
    29761 tccagccgtt atttcgaaag agaaaaccga tctgcctctg tctctatcat tcgggaaaca
    29821 ctaccgttta tttttgtcgg ctcagtcatt actatcgttc aaatgatcga ccaagtaacg
    29881 atgaaaccac tgcttcactt tttccgtcca gagatcgcag atcagcaact ggaattctta
    29941 ttcagccgtg cttctgtcaa tccaaataaa ttgacattga tcctgatctc catggtagga
    30001 acagtagcta taagcagctt gccaatatta agcacgatga agaaaaaaga tcggatacaa
    30061 atcgaaaaaa cagtaggaga tagtttttcg attgcgttat tgattcttct tccttcattg
    30121 actggaatgt ctttattagc tggaccacta tacacattgt tttttggcta tgatcctgaa
    30181 agtgtcggat atttccaaat ggctttgcta gcttctttgt ttttctcttt attcacgatc
    30241 ctatctacga tgcttcaatc tttgaatcac catcgttttg cgatccgatt aactgtagaa
    30301 gcaattatcc tgaaagtcat cttccaagta atcggattag gattagttgg cggatacggg
    30361 atgagcttat caaatggctt agcattcggt attgtctttg ttcgcggcta tcactttatg
    30421 tgcaaagaat accgaatagc acctttagca aagatcagca attttttctt aaaaactttc
    30481 cgctccaccc tgattatgct tgcagtatgt tttgccgttt tctttttgct gaatcagcga
    30541 ttgtcaatgg aatcaaaaag ctatgcaatg atttattgtg tggctgtagg aagtattggc
    30601 ggcttagtat ttttattttc tcaattcgga aaaaatgggt ttcgaatgtt gaaaaatgtt
    30661 aaacatcata gcagaagcaa agaataggtt aactaatcgt tttttgctgt cacttgaaaa
    30721 acggcaactc gtatgattac gcttgtcgtt tttctatttt ccaattttag tttcatatct
    30781 aatcttactt atgatatagt tataaggtct ggaaaaattc tttgaaacga ggaaattaaa
    30841 cacatgaaac ttgcagtagt tacagatagt tcggcatatc tgccggaacg tatcaagaac
    30901 catcccgact tattcgttat tccaatccct ttgattatgg atgggaaaat ttataacgaa
    30961 ggaatcgata tcgaagcgga tgaatattat ggacttttaa aaaacagtaa agattttcct
    31021 actacttcac aacctgtcgt aggggaagtt ttgggtttat atgaggaatt gaaagagaaa
    31081 gggtatgaca cgattttaag tatccatctt tcttcaggga tttctggctt tgtcaacaca
    31141 ttatttgcga tgaaagatga catcagcgga gtaacggtca ttccttatga ctctaagatc
    31201 actagtatgc cgatgggaca catggtagaa gctgccttag acttaaatga tgaaggtcag
    31261 tcccttgatg aaatacttgc acatatcgat cgaatccgag ataataccta cgcttatctg
    31321 attgtagatg atttgaacaa tttagtacga ggaggacgtt tgacaaatgg tgcagcgctg
    31381 attggcagct tattaaaaat caaaccgatc ctgacatttt ctgaagggaa aattgtttta
    31441 ttcgaaaaaa tccgttcaag taaaaaagca tttgctcgag ctgaagaaat tattggtaga
    31501 agaaataacg aaatacaacc gccagtcaaa ctttacgtga tacatgcaaa taatttagaa
    31561 gtagcgattg cggagaaaga gaaattgcag aaaaaatatc caaatgcaga aatcgaaatt
    31621 ggtcatttcg gaccagtcat tggtacacat ttaggtgaaa aagccatcgg cattgccatt
    31681 tcagcgcaat aattcctttt attcaaaaaa cataccaaaa atattccaac atcatcttgg
    31741 actttctaca tgttactaat gagcgtgtaa aagaacgaga tggtgttttt atttctatca
    31801 atgaagctct ttttctttgc aatcctcact tcaatcctct ataatgtcgc atatagttta
    31861 gtaaatgagt aaactactaa tttacttatt tactaaaaat aaaaggatga ggagttaaaa
    31921 taatggaaat accaacaaat ttaaaacata aaccagtaat cgttgtagaa gactatgata
    31981 aagttgatgg aagaaatgca ttaaatacgg atgcaaaagg gctttcactg ggccttgctc
    32041 agtggaatga tcgtggaaaa gtcgatatct caggcaaggt atggcgacat actggagaaa
    32101 aatggtcacg acagtcggaa gaattaccaa tcacacgtat tttagattta gcgatcttag
    32161 ctgcacaagg aagtttatac ttccaagatg cttatcgtta tgaaaaattt tatgatccag
    32221 aaaatccagt cgtagacatc attggattac aagggaaccg aatgacggta gaagtagata
    32281 ccaaaaatcc aaagatcgat gaagacatca ttttgtatta cgatacacta caaaaagacg
    32341 gagaactgat tggggaacga ttccgtattt taaaacgtct tttagatgag ctaggatatt
    32401 aatagacaga gatgatcaaa aggggaagag aagcatggag aatttctcac taacagaaaa
    32461 ccgaaccttt tcacggctag aaaagcaaat gatctggaag aaaccgaaaa gccatcggac
    32521 aagtgcagaa gaatggcgga tcgcctccga aatcaaaggg aattggcaag atcctgaaat
    32581 gaaaatcagt aacgtacttt tggaaggaga tgccgggtcg gggaagacac aattagccaa
    32641 agcactatct gctgatctgc aacttcccta tacaaaagtg acctgttttg cagatatgga
    32701 caaatcagat gttttcggag ccttattacc tgtagtagat tctaataagg aacaagacca
    32761 agaattacta gaagctattt accaaacaga tacacttgaa gctgtactga cactgatcca
    32821 gaaccattac ggcattgatc ctttttctgc taaagaaaaa ttagcagagc tagttcaaag
    32881 gatcgaagct gattatccag atgcaatcca ttacagctat tacccttctg aaatcgttcg
    32941 agcgattgaa aaaggatatt tattagagat tcaagagccg actgtcatcc gagatgcctc
    33001 tgttcttgtg gcacttaact cagcgctcga accaaatggg atgttgaatt taccgacagg
    33061 aatcattcgt cgccatccag attgcgtcat tgtgatcact acaaatcgaa attaccaagg
    33121 aaatcgccca ttaaatgaat ctttaagaga tcggatgcaa catgcggaaa aaatggatct
    33181 tcctgcctta gaagtcatgg cagaacgtgc gatggcgaaa actatgatcc aaaaacaaga
    33241 acttctctta aagatggcag agattatccg tttgttggat gaaactgcaa aagctaacgc
    33301 catcaaaggt gtagcaggaa tgcgttctta tttttattgg gcaaatacct ataagcaagg
    33361 acaagattta ctccagtcga tttatccaaa agttttgtat aaattatcca ctgattcaga
    33421 tgaattggca attcttgaac aagctttgtc tgacagtgga ttgctactgg aacttcagga
    33481 catattgaga aaagaaaaat ggggtcatcc tcaatctgag catacaaaag gaagaaccat
    33541 tagcgccgaa gaagcaaatg aacgaaacat cactgaaaat gctgaagaaa ttctgcgctt
    33601 agatgaaaag aaatcgttgt ctgctgaaga accaaatgag ggagaagaga aacaagaaga
    33661 aacaatagaa aaaaacgaga ttcctcctca aatgcaaaaa gaacgcagta gcgatatcga
    33721 aggaaaaaat caaaaagaac aacaaacagg agatgattct caagaaatgt ctgcttctga
    33781 catggaagca catgataagg aaatcaagaa gcaactgaat aaagaagcgc gacaaatcat
    33841 gaaggaaacg attcatgaaa aagaaggtct catcgttcac cgaccagctt tccaaggaaa
    33901 aacgccggaa gcacgtgagc tacacatgca agtaatgcca atagtagaat cacttagccg
    33961 gcaaatttta gagttactgg ataatgaaca aacagagacg taccaaaaag gaaaatacga
    34021 aggtcagcgg ttcaatgcaa gcaaagtagc atatggtgat ttgagaaatt ttgacaaaaa
    34081 gaacccgcca catgagcaac cttctttagc ggtagctgta cggatcgatg aatctgggtc
    34141 aatgatacgg gatgatcgga tcgaagcggc aaaaaaagca gcgattgcca ttgccgaatt
    34201 ttctaagaaa gtcgatatcc cattgttgat ttacggagat acagcagacc gttcgtcaag
    34261 agaaaagact tctttgtttt cttataaaga atttgaagac ggatttcaat ggttaaatga
    34321 aaaattagtc actatgaaac caaggcaaaa caatcgtgat ggtgctgcac ttcgtttagc
    34381 agcagaaaaa ttaaacagac aatccgcaac aaccaaactg ttgcttaata ttagtgacgg
    34441 tcagccaaaa gcgttgccgg attatacagg caaaaaagca aaagaagata tccagtctgt
    34501 tttgaaagaa tatgaacgtc aaggaatcct atttgtctcc gcagctattg gccaagacaa
    34561 agaagaaatc aagtcgatct acggtgaaag tcgttttgta gatattactg acttgaatga
    34621 atttcccaag caaatgattc aactgattgc ccgctatcta tgataaaata aagctcaacg
    34681 aacgcactta gcagattcgt tgagcttttc gtttctagtt accggtaaca aggatacttc
    34741 taaaatagaa tcggttataa tcaagaggga ccgttaaagg agtgaaacga tatgatacaa
    34801 gaacaaaaat ggtggaaaga agcagtaggc tatcaaatct atcctgctag tttcaaagat
    34861 agcaatggcg atggtcaagg agacatcaat gggatccgtg aaaaacttaa ttatttgaaa
    34921 gatcttggta tcggctttat ctggatcaat ccgatctatc aatctccatt tgtcgataat
    34981 ggttatgacg taagtgacta tcaagatata gaagagagat tcggaacgat ggaagatttt
    35041 gatttattgc taaaagaagc acatgaatta gggatcaaag tgattatgga tcttgtcatc
    35101 aaccatagtt cggatcagca tcaatggttt gaagaatcga aaaaatctaa agaaagcccg
    35161 tatcgcgatt attacatttg ggtcgacggg gtagatggca aagaaccgaa taattggaca
    35221 tcgattttcg gcggttctgc ttgggagtat tctcatgaaa ctggacagta ttatctgcat
    35281 gtttttgcaa aagaacaacc agacttaaat tgggaaagcg agaaattgaa agaagaacta
    35341 ttcaatatga tccgatggtg gttggataaa gggatagatg gatttcgttt agatgcgatt
    35401 tctcatgtaa aaaaagatga atattcagta aaagccacag agaacccttt ctcacccttt
    35461 caaaatgtct caggaatcga agaacatttg accgatttga aacatgtttt tgaagagtac
    35521 gatatcatga ctgtcggaga agcaagtggt gtcactgcag aagaaggacc acaatgggta
    35581 gggaaagacg gttatttcga tatgatattc gaatttgatc atatccatat ctggcagcaa
    35641 gaaaaagaag ggcaattaga tgtccttaaa ttgaaacttg cattaagcgc ttggcaaact
    35701 tcattggatg gtatcggatg gaacgcttta tatatggaaa accatgatgt tcctcgtgcc
    35761 gtttcagtgt ttggagatac tcgtcccgat ttttgggcta tgtctgcaaa agcaatcgct
    35821 atgatgtatt tctttttgca aggtacgcca tttatttatc aaggacagga aatcggaatg
    35881 acgaatatgc cctttgaatc gatcgatcaa gttgatgcag tagattcgaa aagactttat
    35941 aaaaggctgc ttgcggaagg taagacaaga gaagaagcat tggatatcat tcgtgaaaca
    36001 acgagagaca acagcaggac acccatgcaa tggacttcgg aacaatatgc tggtttttct
    36061 acacatgaac cttggctgat cactaatcca aataccaaaa cgatcaatgt agaacaacaa
    36121 gaatatgaac cagagtcggt cctgcaattc tataagaaca tgatccgcat tagacaaacc
    36181 aataaaggtc tgatatacgg ttcttataaa gaatatcttc atgaacatcc acaactttat
    36241 gtctatgaaa gatatttaga agatgaacaa tatcttatta tggtaaactt aacagaatca
    36301 cttgctgact atgaacttcc aaaagaagca gatcagtcct ggacattact cttgtcaaat
    36361 tcctctagcg gagaatttga agctaaaggc atactagcac cttatgaagc tcggttatat
    36421 aaaacaaaca agtaaaactt cctcgttaaa gttcattagt tggactttgc gaggaagttt
    36481 ttcagattgc tctgtcaatt actcatttca ataattcgct ctaggaccac cgatatattt
    36541 aggacgagag cgaagggctg tcacgtgagc ttgtccaagg gttttcaaac gaggtctgac
    36601 aggtacttgg acatgtttga tatgcatacc gattgatgtg tcaccgatat cgataccggc
    36661 ttgtccaact acgtgttcca cttcgacagg atcattgaac tggtcaaaag cagcaacaga
    36721 acaagcacct ccagcatgta gtgcaggaac aacagagaca atttcgaaat tttttgcttc
    36781 tgccactgtt cgttctacta ctaatgctcg gttcaaatgt tcacaacctt ggacagctag
    36841 cgcaatttct ttaggatcca acaactcttt taacgtacgg atgatccatt gaccaacttc
    36901 cgcactggaa ttttttccaa tatgtcctcc aacgacttcg cttgtgctgc atcctaaaac
    36961 aaaaagatca ccttttttca agtgtgcctc agccaatatg tcattaacta tttcagtcaa
    37021 ttggtctttt aattcttttt ctgacaactt cattttctaa aaccttcttt ttcaattaat
    37081 attgcttccg tgcttgaata cgttgaagac ttgcagttat aggaaaggca agtcccattc
    37141 caatcagatt ttggaagatg tttcctggta tagaagccac tccagccggc caatcatata
    37201 aaatccaacc ggcgatacca tagccgatga tcataactaa gcttcctaat aaaagcccta
    37261 atccccacat acgagtagaa gatttgctga aagaaccagc aacatatcct tgtaacccgt
    37321 ggatcactaa tgaaaaaact gcccactgcg gatatcctga aatcaaatcg atcaatagac
    37381 cactggaagc accaacaact aatccacccg ttggaccata aagaaaagca gcggtataga
    37441 tcccggcctc gcataatgtc acaaatccat tcgtagccgg tacagggatc aaaattgtta
    37501 atgaaagggc aactgtcaac gcaatcagca tagcatagat cgttaattgc ttagttttca
    37561 tttctcattc ctcctttttg aataccgcca gaccagacac ttccggtatg atcgttcatc
    37621 agcacgccat tagaaataca atgggcaaca aattttttac tttctgctac tgctttggta
    37681 aaatctgccc ctaacacaag attcgctgtt attgcagaag aaaaggcaca accggccccg
    37741 tttactgttg tagtgtcgat ttttttatga gaaaatacct cataatgatc aattgaatag
    37801 agaagatcca cagcttcatc tccagccatc cttgtgccgc ctttgatcac aatgtttttt
    37861 gttcctgaag cagtgagttc tttagcgaga tggatcattt ctgttaacga agagggaaga
    37921 gcttgaccag aaagtaaagc agcttctgcc aaattaggcg taatcatcgt aacaagtgga
    37981 aaaagttctt cgatgagctg cgaaatatac aattgattga tcacagcttc agtttctttg
    38041 aatgccaaaa cagggtctaa aatgattggg atattttgtt ttgtttttat gaagtctcga
    38101 acaaccatga ttgcttcact tgaattcaat aacccaattt tgataccatc taatgaagtc
    38161 attttatcaa tcgaaactaa ctgtcgttta agcaattcca aagatataga ttccagcata
    38221 aatcgctcat taatatctag tgcccctata gaagtcaagg cgcttagtcc gaatagacca
    38281 aaattctcaa aagtttttaa atctgtttgg attcctccac cagcaaatgg atcagaaccg
    38341 ccaattgtca agattctttt cataacattt tcctccatga ataagagtat aacgaaattt
    38401 tcaaaaaaga aaaacagcca attggcatat ttttatctca tccaatttaa aaaaacaaaa
    38461 agaaaagaaa gaccaaaatg gatctttctt tccttaaata gttaggactt ttgtgatttt
    38521 aattctttct cgatttgaag ccgttgcact ttcattgtag ctgttcgcgg gattgcatca
    38581 aaatcacgga tgatagggac gttcaagcga ggaagttcat ggacttgctc ccaccatcga
    38641 ttccaatcca tttctttatc aggagctaaa gcaataatcg gttgtggaga atgattttta
    38701 tcccttacaa tcactacttc tgccaaaaaa tctaacgaat ctaataaaaa gtcttcaata
    38761 gctaatgtac tattgatcgt ttcgatcaaa tccacttgcc gatctttcaa aaataggtgg
    38821 ccatgcttat ccataaaacc gtaatctccg ctatcccacc aatcgccata aacattttcc
    38881 tggaaccgtg catcttcctt gtaataagtc aaagcccgtc ctttagacag taattgtata
    38941 tgaccatctg tgttttcagg taggacattc ccaactgaat ctgtaatccg agcgcttgtc
    39001 atgtcttcca gtccaacgcc catatctctt gcatcacttg ttttcaaact ctctagtgta
    39061 tgagccttaa gaatcattgg tccgcattca ctttggccat atacttgaag aaataccgca
    39121 tcctgtgcca tcgacgttcg caaaaatgtc ttcattgtct ggttgtttat agcatcaaaa
    39181 gtggagtgat agtatcggat acccgaaaaa gcttctggat gctccttagc agtaaaacgc
    39241 cactgaacaa agttattcgg atgggtctct agtgcaattg gccggtgagc ttccaacata
    39301 tgaacaactt ttgaactttg tgcgtttgct aaaggcatca taggaaatcc catggacatc
    39361 aaagaagaga taccaatatt gaatctggaa tgcactggag agatgtgaaa agcgattaat
    39421 ttcttttccg aaatttttgt gaaaactgtt ttttgccatt tcgtccgcca tcccatagaa
    39481 tgagcagaat gacaaataag tttagggata ccagttgtac cagaagtatg ggtcatataa
    39541 gaaatttcat ttttgtctaa aaatgattga gaaacagaca aagcaggttg ttccattaaa
    39601 taaagaatag gaa
//
LOCUS       DAFTHM010000014        39223 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFTHM010000014 DAFTHM010000000
VERSION     DAFTHM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39223
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.014"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            131..505
                     /locus_tag="L7C88_000762"
     CDS             131..505
                     /locus_tag="L7C88_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBP9557617.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="L7C88_000763"
     CDS             complement(619..1248)
                     /locus_tag="L7C88_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBP9557618.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="L7C88_000764"
     tRNA            complement(1382..1454)
                     /locus_tag="L7C88_000764"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="L7C88_000765"
     tRNA            1668..1741
                     /locus_tag="L7C88_000765"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="L7C88_000766"
     CDS             complement(1879..2043)
                     /locus_tag="L7C88_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557619.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="L7C88_000767"
     CDS             2338..3666
                     /locus_tag="L7C88_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBP9557620.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="L7C88_000768"
     CDS             3868..4701
                     /locus_tag="L7C88_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBP9557621.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="L7C88_000769"
     CDS             4717..5454
                     /locus_tag="L7C88_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBP9557622.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="L7C88_000770"
     CDS             complement(5609..6577)
                     /locus_tag="L7C88_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBP9557623.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="L7C88_000771"
     CDS             6809..7642
                     /locus_tag="L7C88_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBP9557624.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="L7C88_000772"
     CDS             7676..8515
                     /locus_tag="L7C88_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBP9557625.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="L7C88_000773"
     CDS             8541..9101
                     /locus_tag="L7C88_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBP9557626.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="L7C88_000774"
     CDS             9300..11021
                     /locus_tag="L7C88_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBP9557627.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="L7C88_000775"
     CDS             11186..12328
                     /locus_tag="L7C88_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBP9557628.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="L7C88_000776"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="L7C88_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBP9557629.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="L7C88_000777"
     CDS             14128..14775
                     /locus_tag="L7C88_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBP9557630.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="L7C88_000778"
     CDS             15168..17813
                     /locus_tag="L7C88_000778"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBP9557631.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGHEKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="L7C88_000779"
     CDS             18123..19436
                     /locus_tag="L7C88_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBP9557632.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="L7C88_000780"
     CDS             19426..20079
                     /locus_tag="L7C88_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBP9557633.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20685
                     /gene="radC"
                     /locus_tag="L7C88_000781"
                     /pseudo
     CDS             20134..20685
                     /gene="radC"
                     /locus_tag="L7C88_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
     gene            20816..21901
                     /locus_tag="L7C88_000782"
     CDS             20816..21901
                     /locus_tag="L7C88_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBP9557634.1"
                     /translation="MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPN
                     TIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREE
                     TTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRV
                     KKKQIRTLRSEEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIH
                     LTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFG
                     KPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTT
                     LNTYVHLSDQDMKNEFNKYLERKEHKK"
     gene            21898..23790
                     /locus_tag="L7C88_000783"
     CDS             21898..23790
                     /locus_tag="L7C88_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBP9557635.1"
                     /translation="MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPS
                     AIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKM
                     LDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSY
                     YVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYF
                     KQLVKRYCKLRLNMDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSE
                     LNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEF
                     VLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKM
                     KKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQ
                     NIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETL
                     KNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGC
                     PHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQI
                     IGSLTG"
     gene            23797..24174
                     /locus_tag="L7C88_000784"
     CDS             23797..24174
                     /locus_tag="L7C88_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9557636.1"
                     /translation="MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNS
                     IAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVME
                     LEKENKKLQNQIQKLYGDLYNKE"
     gene            24328..25110
                     /locus_tag="L7C88_000785"
     CDS             24328..25110
                     /locus_tag="L7C88_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)-Ia"
                     /protein_id="HBP9557637.1"
                     /translation="MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRI
                     NSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYP
                     PKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
                     DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
     gene            complement(25236..25967)
                     /gene="erm(A)"
                     /locus_tag="L7C88_000786"
     CDS             complement(25236..25967)
                     /gene="erm(A)"
                     /locus_tag="L7C88_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HBP9557638.1"
                     /translation="MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHF
                     TKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNI
                     PYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
                     LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKH
                     ANVTNINKLSKEQFLSIFNSYKLFH"
     gene            complement(26025..26084)
                     /locus_tag="L7C88_000787"
     CDS             complement(26025..26084)
                     /locus_tag="L7C88_000787"
                     /inference="COORDINATES: protein motif:HMM:NF033690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythromycin resistance leader peptide"
                     /protein_id="HBP9557639.1"
                     /translation="MGTFSIFVINKVRYQPNQN"
     gene            26476..27138
                     /locus_tag="L7C88_000788"
     CDS             26476..27138
                     /locus_tag="L7C88_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBP9557640.1"
                     /translation="MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGC
                     GSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIV
                     SRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCF
                     KFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVW
                     TK"
     gene            27373..27516
                     /locus_tag="L7C88_000789"
                     /pseudo
     CDS             27373..27516
                     /locus_tag="L7C88_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            27666..27866
                     /locus_tag="L7C88_000790"
     CDS             27666..27866
                     /locus_tag="L7C88_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBP9557641.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(28120..29799)
                     /locus_tag="L7C88_000791"
     CDS             complement(28120..29799)
                     /locus_tag="L7C88_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBP9557642.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(29801..30013)
                     /locus_tag="L7C88_000792"
     CDS             complement(29801..30013)
                     /locus_tag="L7C88_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBP9557643.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            30406..32136
                     /gene="efrA"
                     /locus_tag="L7C88_000793"
     CDS             30406..32136
                     /gene="efrA"
                     /locus_tag="L7C88_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBP9557644.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            32133..33893
                     /gene="efrB"
                     /locus_tag="L7C88_000794"
     CDS             32133..33893
                     /gene="efrB"
                     /locus_tag="L7C88_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBP9557645.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            33988..34185
                     /locus_tag="L7C88_000795"
     CDS             33988..34185
                     /locus_tag="L7C88_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557646.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            34338..34823
                     /locus_tag="L7C88_000796"
     CDS             34338..34823
                     /locus_tag="L7C88_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBP9557647.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(34927..35520)
                     /gene="clpP"
                     /locus_tag="L7C88_000797"
     CDS             complement(34927..35520)
                     /gene="clpP"
                     /locus_tag="L7C88_000797"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBP9557648.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            35700..36227
                     /locus_tag="L7C88_000798"
     CDS             35700..36227
                     /locus_tag="L7C88_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557649.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            36318..37055
                     /locus_tag="L7C88_000799"
     CDS             36318..37055
                     /locus_tag="L7C88_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBP9557650.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            37059..37976
                     /gene="miaA"
                     /locus_tag="L7C88_000800"
     CDS             37059..37976
                     /gene="miaA"
                     /locus_tag="L7C88_000800"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBP9557651.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            37978..39207
                     /gene="hflX"
                     /locus_tag="L7C88_000801"
     CDS             37978..39207
                     /gene="hflX"
                     /locus_tag="L7C88_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBP9557652.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        13179 a         6425 c         8148 g        11471 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt catgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg ttttaaccat agtataataa
    20701 ataatagtag ttaaagtagt ttaagaggag atattaaagg gatattttac tttaaataaa
    20761 aattaacaag gtttataatt tgtagtagtt aaagtattta aagaggtggg aacatgtgaa
    20821 ggttcaaagg atagaagtgg agaataagcc gtatccattg tatttattac tagataaaga
    20881 ataccagcta atagaaccag taatgaaatt tattaaatac ttagataata ctggtaagtc
    20941 tcctaatacc attaaagcat actgctatca tttaaagttg ctgtacgagt tcatggaaca
    21001 gagaggtgtt attcttaatg atattaactt tgagttgtta gcagacttcg taggttggtt
    21061 gagatatcct tcagcatcaa atgtaattga tcttcagtca aaaaaagcca taagagaaga
    21121 aacgacagtg aatacaattt taaatgtagt tatgagtttt cttgattatt taagtagatt
    21181 aggagaattt aaatcaattg atgtatttaa acaagcaaag ggaagaaatt tcaaaggatt
    21241 tttacatcat gttaataagg gtagatacca aaagaatgtc ttaaagttaa gggttaaaaa
    21301 gaaacagata agaacattga gatcagagga agttaagcaa attattgatg cttgtcatac
    21361 gaaaagagat aaattaattt taatgcttat gtatgagggt ggtttaagaa tcggtgaagt
    21421 gttatcgctt aggcttgaag atattgtcac ttgggacaat caaatccatt taacacctag
    21481 agatgttaat gttaatgaag cttatattaa attaaggaag gaaagaacaa tacatgtgag
    21541 taaagaactt atgtcacttt atacagatta cttgatatat gagtatagtg aggaattgga
    21601 gcatgattat gtttttattt ccttaaaaga aggctatttt gggaaaccac taaagtacca
    21661 aagtgttctt gatctagtta gaagaatagt taaaaggact ggaatagaat ttacatcaca
    21721 tatgcttcgc cacactcacg caacgcagct aattagggaa ggatgggatg ttgcgttcgt
    21781 tcaaaagaga ttaggtcacg cacatgttca gacaacgtta aatacctatg ttcatctttc
    21841 agatcaggat atgaaaaatg agtttaataa atacctcgag agaaaggagc ataagaaatg
    21901 aatgcttcta gtaaaaggaa aattattagt cagagtgaga ttagcaaaaa aatagctgta
    21961 atgaatgaag aaatgcaggg gttttgggct aataatagtt gggatataag aaaatgtcca
    22021 catccttctg ccatagaatt aagtaagaat cctgctttaa ggaatcgttg ggttcgtttt
    22081 gaacgtgtta aaaatctgtg gttaagaaca gaattgaaat atttttattt ttaccattta
    22141 aacaatggaa tatggaatgc aaaaactgtc tggattagaa aaggaacagt aattaataaa
    22201 atgttagatt tcttagattt aaagtatcct agcattactt caattactga agttcctatt
    22261 gaaaaagcaa tgacggagta tagaacttat ttgacaaaac ggggtgttag aattaccact
    22321 actaattata agattactgc taatcaagaa aaaacacctg taaaagctaa ttcctactat
    22381 gttactaatc taaaacaatt tatggagttt tatgagaact tttattttga tggagaggag
    22441 tgggataaag acgtttggga tagacgtaac ttacctttgc cagatgataa ggttaaccca
    22501 acacaatatg aatatacaat taactttaaa gggtttcgga atacatattt taaacaactt
    22561 gtaaaaagat attgtaagtt gagattgaac atggatagct tttcctatgt aagtgatatt
    22621 gcccaaagac ttaaagagtt ctttaatttt ctggacatga aatttaaaca agttcagaga
    22681 gtacaccaat taacgagagt ggaaattgaa gcatatttaa gtgaactaaa catgatggga
    22741 ataaaaccta gtacaataac tgggaggatc tctatattgg aaggactatt tagtaccctt
    22801 cttaggctag aatgggatga tgttccttcc aaaatattaa tttattctga ggactatccg
    22861 aaaataccaa gagcaaaacc acgctttata gatgaattcg tcctagagca attgaacagt
    22921 catcttgata aattacccga atatatagct acgatgacta tgattgttca agaatgtgga
    22981 atgaggataa gtgaattgtg caccttgaaa aaaggctgtc tattagagga caaagatgga
    23041 gatttctttt taaagtatta tcaatggaaa atgaaaaagg agcatatagt tccaatatct
    23101 aaagaggtag ctttacttat taaagttcgg gaagataaag tttcagagga atttccagat
    23161 agtgaatacc tctttccaag aaaagatgga tcgccattaa aacaagaaac atttagaggt
    23221 gagttaaata aattagctta tgagcaaaat atagtggata aatcaggtga gatttataga
    23281 ttccatgccc atgcctttcg ccatacagta ggaacaagaa tgattaacaa cgggatgccc
    23341 cagcatattg tgcagaaatt tttggggcat gaaagcccag aaatgacaag cagatacgct
    23401 catatctttg atgaaactct aaaaaatgaa tttactaaat ttcaggaaaa actggttacc
    23461 aataatggag atgtgcttga tctagatgaa gataatgaag tcgatgatgt agagcttcaa
    23521 tggttcaaga aaaatataaa tgcacaagtg cttccaaatg gttattgtag attgccagta
    23581 gtagcaggtg gttgtccaca tgcgaatgca tgcttagatt gcactcactt ctgtaccagt
    23641 aagcaattct taccacagca cgaagaacag ttagagcgta cagaagagtt attagccata
    23701 gctaaggata aacaatggca aagacaagta gagactaata gccgtgttaa agagcgttta
    23761 gaacaaatca ttggaagttt gacggggtaa ttatcaatgg ataaacaagt tagaaataca
    23821 acagaaattg tacgtttggc gaagcagaaa tcaaaaaaga caagggaaaa agtagacaaa
    23881 gcgatttcta aattttcgat tgaaggtaaa gttattaatt ttaattcaat agcaaaggaa
    23941 gctaatgttt ctaaatcatg gctttataag gaacacgata ttaggcaaag aatcgaatcc
    24001 cttcgtgagc gtcaaataac agcaaatgta gtctcaaaac ccaagaaaag ttctcgttcg
    24061 gaggaaatcc ttattaaaac cttaaaaaga agagtaatgg aattagaaaa agaaaataaa
    24121 aaattacaga accaaattca aaaattatat ggagatctgt ataataaaga ataattatta
    24181 atctgtagac aaattgtgaa aggatgtact taaacgctaa cggtcagctt tattgaacag
    24241 tcatttaggt atatgtccaa tctagggtaa gtaaattgag tatcaatata aactttatat
    24301 gaacataatc agttacgagg tgaaatcatg agcaatttga ttaacggaaa aataccaaat
    24361 caagcgattc aaacattaaa aatcgtaaaa gatttatttg gaagttcaat agttggagta
    24421 tatctatttg gttcagcagt aaatggtggt ttacgcatta acagcgatgt agatgttcta
    24481 gtcgtcgtga atcatagttt acctcaatta actcgaaaaa aactaacaga aagactaatg
    24541 actatatcag gaaagattgg aaatacggat tctgttagac cacttgaagt tacggttata
    24601 aataggagtg aagttgtccc ttggcaatat cctccaaaaa gagaatttat atacggtgag
    24661 tggctcaggg gtgaatttga gaatggacaa attcaggaac caagctatga tcctgatttg
    24721 gctattgttt tagcacaagc aagaaagaat agtatttctc tatttggtcc tgattcttca
    24781 agtatacttg tctccgtacc tttgacagat attcgaagag caattaagga ttctttgcca
    24841 gaactaattg aggggataaa aggtgatgag cgtaatgtaa ttttaaccct agctcgaatg
    24901 tggcaaacag tgactactgg tgaaattacc tcgaaagatg tcgctgcaga atgggctata
    24961 cctcttttac ctaaagagca tgtaacttta ctggatatag ctagaaaagg ctatcgggga
    25021 gagtgtgatg ataagtggga aggactatat tcaaaggtga aagcactcgt taagtatatg
    25081 aaaaattcta tagaaacttc tctcaattag gctaatttta ttgcaataac aggtgcttac
    25141 ttttaaaact actgatttat tgataaatat tgaacaattt ttgggaagaa taaagcgtcc
    25201 tcttgtgaaa ttagagaacg ctttattact ttaatttagt gaaacaattt gtaactattg
    25261 aaaatagaaa gaaattgttc cttcgatagt ttattaatat tagtgacatt tgcatgcttc
    25321 aaagcctgtc ggaattggtt tttagtgaaa agaacacgat attcacggtt tacccactta
    25381 taaacaaaag atcgatactt tttgtagtcc ttctttgaaa tcaatggttg atgtcgttca
    25441 agaacaatca atacagagtc tacacttggc ttaggatgaa aatatagtgg tggtactttt
    25501 ttgagcattt ttatatccat ctccaccatt aatagtaaac ccaaagctcg ttgcagattt
    25561 tgcaatcttt tcgcaaatcc cttctcaacg ataagatagc tatatttagc ctgactttca
    25621 aaggtaattc ttttgacaat atccgtactg atgttataag gaatattacc atatatctta
    25681 tagtttatat gttttgggaa ggaaaatttt agaatatccg tttgaatcac ttttatattc
    25741 tcagaggggt ttaccgcttc tttagtcact tgacataagc ctccatcaat ttctatagca
    25801 gtaactgatc gactcatttt gactagctct ttggtaaaat gtccttttcc tgatccgatt
    25861 tctattacgt tgtcttgttt actgatattc gtgtgattca atatttcttt tacatgcttt
    25921 ttagaagtaa taaaattttg cgtgtcttta gggtttttct ggttcattat aaccttctcc
    25981 ttactggtta taatgaactg acattaagcg ttcattataa ccaattaatt ttgatttggt
    26041 tgataacgaa ctttattaat aacaaatata gaaaaagtac ccatactttt atctcctttc
    26101 catttttttc attatgaatg agataaagta atttctacta ctgcgatact ggtgcacata
    26161 attgaaacct ccttatgtaa ctgaatatga ttgtatcatc ttttcatttt agaataaacc
    26221 tttatatgta attttgcact tgacacttca gatggacgtt ttcttcaaaa taatatgttt
    26281 tgaaacttga taagagaagc cactgtcttt actaaaaagt aaaggctgcg ataaaggaca
    26341 gtgactttaa taaagttgca ctgttgtatt gtctttggat aaaattgtct aaagggaagt
    26401 tttatcccca acgaaaaaac atctaaagtg gtaagtaatg aaagaatgtc gataaagtag
    26461 gaatggggga tctttttgaa tacaatagaa tcacagtttg ataaggttgc agaagattac
    26521 gatttcgtga atgagctttt gaatgattat tcattctttg tgtctaatat gtctccaaag
    26581 aaaggcagag cattagatat cggatgtggc tcgggtttgt tagtggagaa attagcaagt
    26641 tattatgatg aagtggtagg gattgatatt tctaatcaaa tgctcgatct tgccaaatct
    26701 aaacgtcaac taacaaatac ggtctatctg aatatgaatg cagaacaact taattttaat
    26761 gagaagtttg attttattgt aagccgaaca acctttcatc atttggatga tatagccagc
    26821 gtaatacagc aaatgaagga actgttgaat gaggaaggaa gaatagttat tcttgataat
    26881 gtatctgaag tcgagacacc gcctacctat gtttataaat taggggcaat ccaagagttt
    26941 ttaccgcatt gtttcaaatt tggaataaaa aatgcgatta gaatttataa tcacaacaca
    27001 tctaaatcat ggcttgagca tttagcttca gataagtacc tatctgaaca aaattattac
    27061 gatttatatg aaaagttgtt gcctggatgc caattccata aaatgggttg ggcaatgggg
    27121 gttgtctgga caaaataact taaagctgtg gctttgaaaa gttgaatttg tgattgtttt
    27181 cagagctatc gggtgcttta gtataaataa caatgaataa aaaatcagcc tgtatcttat
    27241 gttactatta agtaatttaa gatacaggtt ttactatttt tgaaataagt accttccact
    27301 tcaaatacat gtattcaaag tgaaagtatt gatttaaatg attcttttgt aatttactct
    27361 tgataatatg aaattccatc gcagcaggat atgaatttta ccaaaaggat acaaaagtgt
    27421 ggagaaatga tggggatcac tgtactggac cacttgatca tcggacgcaa acgatatttt
    27481 agtttgagag aagaaggaat gatggaagag aagtaagttg ctttcttgca aaaaaaatga
    27541 agcaagtgta caattatatt gtaattttgt ttgggaatag aagttgaaac atctgttgca
    27601 cctctatcgt acacgagcaa tgttacaatt taaattagtg cttttggcac gaggaggata
    27661 ttattatgga aaacggaaca gtaaaatggt tcaacgctga aaaaggattt ggatttatct
    27721 cacgtgaaga tggaagcgac gtattcgttc acttctcagc tatccaaggt gacggattca
    27781 aaacattaga agaaggtcaa gcagtgactt tcgacgttga agaatcagac cgcggcccac
    27841 aagctgcaaa cgttgtaaaa gcttaatttt atctgtaaat caaattgatg gtagacatca
    27901 atttttacga gagaacaaag cgagtaacaa aaatacctgc cacaagagac aatttctctt
    27961 gtggcaggta tttttttgta tgaaaaagta aataaattta agaggctatg aaagagccac
    28021 cttgtatcaa ggaataagaa caaacaaaaa tggcttctca tgtttttcat ttgttttctc
    28081 ttatattcag gacaaggtgc tgatttcata acctcttatt tattcttcat ctggtgtcat
    28141 taccattggc aaaatcattg gatgtctttc tgtacgttcg aataagaaag gctgaagcgc
    28201 gccagtcatc gcttctttca atttatattc tgaacagtca ggtccattca aacattctct
    28261 taaagcgtgg aataagattc gctgagcttc attgatcatt tctcctgatt ctcgcatgta
    28321 gacaaatcca cgagagagaa tatctggacc agccaagatt tcttttttct tgatatccac
    28381 tgtcgcgaca gctaatacaa gaccttcttc tgaaagcagg tgacggtcac gtaaaacgac
    28441 attaccaata tcaccgatcc cgctaccatc gatatacaca tctccagcca caaaatgccc
    28501 agcaggacgc gcagaatcgc tagttaacgc taaaacatcg ccattttcca tgatgaagca
    28561 gttttctgca ggaacaccta catcttgtgc tagagaagca tgtactttca acatgcggaa
    28621 ttctccgtgg acaggaataa aatattttgg cttcatcaaa cgaagcatta atttttgttc
    28681 ttcttgtcca ccgtgaccgg aagtatggat gttattgatt tttccgtgaa tcacttctgc
    28741 accagcttca gacagcaaat tgatcaaatg attgacactt gttgtattac caggaatagg
    28801 tgaacttgaa aagatcactg tatcgtctgg ctggatttgg atttgacggt gagtaccatt
    28861 cgcgatgcgg ctcaacgcgg ccatcgcttc tccttgagaa cctgtacata ggatcatcgt
    28921 ttcattggca ggcaagcgat tgatttcgtg tgcatctaca aatgtgccgt ctggaacttt
    28981 gatatatcct aaacgttgac cgttgacgat ggcattttcc atgcttcgtc cgaaaacagc
    29041 gattttacga ccagttgcca cagcggcatc tgctgcttgc tgcaaacgga agatgttaga
    29101 agcaaagctg gcaaaaatga tacgtccttc gatttttgaa aagatcttca aaatagaatg
    29161 cccaatcgtt ttttctgatt tagtaaatgt tggaatctca gcatttgtac tatcagataa
    29221 aaggcacaag actccttctt ccccgatacg agccatttta tgcaagtttg ctggttcgcc
    29281 aacaggagtg aaatcgaatt tgaagtctcc agtcgctacg atatttccag aaggtgtttt
    29341 caccacgatc cctaatgcat ctgggatact atgggtcgtt ctgaaaaagc tgacagaagt
    29401 ctttctaaaa cggatgatcg tatcttcatt gatctcatgg agctctgcat ctcgaagcaa
    29461 gccatgctca tctaatttgt ttgtgatcaa cgctaatgcg agaggaccag catagatagg
    29521 aatatttgct tgtttcagca agtagggtat tccgccgatg tggtcttcgt gcccgtgagt
    29581 aatcaccaag gcttttactt tgtgtaagtt ttgtatgatg tagctgtagt cgggaatgac
    29641 atagtcaatt ccaagtaaat cgtcttccgg gaatttgatc ccggcatcaa tcaaaatgat
    29701 ttcatcttgg aattgtaccc catacgtatt tttcccgatt tcacctaatc caccaatagc
    29761 aaagacgcct gtctcgttat ttttgatgga aagtttcata ttaaaactcc actaatgaga
    29821 aatcagcatt ttctttttcg tactctagat gacttccttc tagaagttga acgaattcaa
    29881 tattgtatgg ggtattttct tccacacgtt ggcgagcgtc tacatcgctt tttgcctcaa
    29941 tgtaaagaga ttttgtttct tcccgtttag ggttgcgtac ttttgtttct tgataataaa
    30001 ctttatagat cattgttttg tctcctttat ctgcgtaaag cagtgattta gctagttgat
    30061 ttttttagac aacacaaaac gaggggacaa gccacctggt ttttcatatg ctttgactag
    30121 aatactggat tcgagtcaaa gagacaagcc tcgtttttgc ttatctgttc ggatattttt
    30181 tcaaccgtac cttctgtata aaaaatatac aacaattaat tgttattcta gcataaaaca
    30241 gcaaataagt atagaaatca actagattga aagaaaaaat caatgtttat catcccgcta
    30301 taatcataat gactttttta tgagagaagt gttctattaa taggctcgtt gtgctatcat
    30361 ttttagtaat gaaaatgtaa caaaagatta aaaggagatg agaaagtgaa actaatgtgg
    30421 cattatacca tgcgttataa gaaattcttg tttttcaatt tcatatgcgt atttggtttt
    30481 attttgattg aattaggact tcctacgatt ttagcacgta tgatcgatgt aggaatccgc
    30541 aatgatgatt ttgattatgt gaagcaacaa gggatattta tgatcgttat tactgtaatc
    30601 ggtattattt tgaatatctt gttaggttat tttggttcga ggattacgac taatatcgta
    30661 gcagatattc gagatgattt gttcgaaaag atccaaagtt attcgcatca ggaatacgaa
    30721 aatctaggcg tatcttcatt gatcactcgt acaacaaacg atgcttatca gatcatgttg
    30781 ttcctgcaaa atattttacg tatcggtttt atggcaccaa tgatgttcat tgtcagtttg
    30841 tacatggtca tgcgtacaag tgtgacactc agtttgtatg tagtaggtgc attaccttta
    30901 ctattattgg cagtcgtagc gattgctaag gtgtctgaac cgttatctaa aaagcaacaa
    30961 aaaaacttag ataaaatcaa cagtatcttg cgggaaaatc tttcaggatt gcgtgtgatt
    31021 cgtgcattcg tcaatgaaaa gtttgaagaa aaacgttttg ctgtagtcaa tgagaattat
    31081 gcttctagtt caaaaagctt attccgtttg atggctgttg cacaaccggg tttttatttc
    31141 ttatttaata tcgtaatggt attgatcatc tggagcgggg cagtgcaaat cgatgcaggc
    31201 gagcttcgtg taggagattt gattgcgttt atcgagtata tattccatgc cttgttctca
    31261 ttcatgttat ttgctagtgt gttcatgatg tatccaagag cagctgtttc agctggacgt
    31321 atccaagaag ccctagatgc caaaccttcg attgtagaag atccaaatgg tatatctgat
    31381 acaaaaacta aagggtatat cgaatttcaa aatgtaacat ttgcttatcc aggccattcg
    31441 caagagccag tgatacgaaa tgtcagtttt acagcctctc caggagagac cgttgctttt
    31501 attggaagta ccggtagcgg aaaatctacg ttgatccaat tgatccctcg cttttatgat
    31561 gtgagtgaag gaaagatctt gatcgatgga gtagacgtga gagattatcg gctaagcaag
    31621 ttgcgagata agattgggtt tattccgcaa aaagcgctgc tatttactgg aacgattgca
    31681 gataatttgc gatacgggaa agaagatgct acgcaagaag aaatggaacg tgcagctgag
    31741 attgctcaag cttcagaatt catttctcga aaaccagatg gatttaatga acatttatca
    31801 gaaggtggtt ccaatttttc aggtggacaa aaacaacgat tggcaatagc cagagccatc
    31861 atacgccgtc cggaaatcta tatttttgat gacagctttt ctgcattaga ttatcaaacg
    31921 gatgcgaagt tacgtgctcg tctgaaaaaa gaaacgacag aatctactgt attgatcgta
    31981 gcacaacgtg tgggaacgat catgcatgca gataagatca tcgtattaaa tgaaggagaa
    32041 gtcgtcggta tggggacgca tcgggagttg ttggaaaaat gcccgattta ttatgatatt
    32101 gccgcttctc aattatcaaa ggaggaatta gcatgaaaaa aaccttttct tccttaaaac
    32161 gtttagctcg atatatcaga ccgtatcgtg agacttttct tttagtgatc ctatttacag
    32221 ttctgacagt ggctttcaac gtggctttgc catatgttac aggacttcct actacagaaa
    32281 tcagccgtaa tattgccaat ggcgaatcaa tcaatttttc ttatatattc aaatgtctca
    32341 tttggatcac agttgttgga atagggtatt gtatttcgca attactttct ggtgttttga
    32401 tgacaaatgt cgttcaaagt gccatgcatg atttgagaag agacatagaa gaaaaaatca
    32461 atcgtcttcc ggtttcatat ttcgataaaa accagcaagg aaatattttg tctcgtgtga
    32521 cgaatgatgt agatgcagtc agcggtgctt tacaacaagc ttttattggt atcgtaaatg
    32581 cgatattggg aattacgttg gctgcagcaa tgatgtttta tatccagccg atgatggcgc
    32641 tgatctctat gatcatgatt ccaacatcga tctggatctc aaaacgagtg atcaatgctt
    32701 cgcagaaata ttttcaaagc atgcagaatt ctcttggtga gctaaacggc tacgtccaag
    32761 aaaatatgac aggttttagt gtattgaaag tatatggacg cgaaaaagaa acattggaag
    32821 gattcaaaaa agttaatcac agcttgaaat actttgggtt tcgtgcagca ttcatttctg
    32881 gcttgatgat gcctctagtt caattaactg cctatgctac ttatattggt atggctgttc
    32941 taggaagctt ttatgttatt actggggcga tcgttgtcgg tcaactacaa gcattcatcc
    33001 aatatatttg gcaaatcagt cagccaatgg ggaacgtgac acaattgtct tcagttttgc
    33061 aaagtgcatc agcggcaacg aaacgtgtat tcgagatttt agatgagcca gaagaaaaag
    33121 aaaacaaagt agatgcttca ctgccagaaa cgattttagg agatgtgaca ttcgatcatg
    33181 tcgattttgc atatgatccg aagaaaccat taatccaaga tttgaatttt gaagtgaaag
    33241 ctggtcaaac cgtagctgtg gtcggtccga ccggtgccgg caagacgaca ttgatcaatc
    33301 tattgatgcg tttttatgac gtagacaaag gagcaataag gattgatgga atcgacacca
    33361 aatcaatgag tcgcagtgat gtgcgttcgc tatttggtat ggtcttgcaa gatgcatggc
    33421 tttatcaagg aacgattgca gataatatcc gcttcggaaa gcttgatgcg acagattatg
    33481 aagtagttga tgctgcgaaa acagcaaacg tagatcattt tatccgaacg atgccagatg
    33541 gatatgatat ggccatcaat tctgagggag acaatgtgtc tttaggacaa aaacagttgc
    33601 tgacgattgc ccgagcagtg gtctccgatc ctaaaatctt gattttagat gaagcaacaa
    33661 gttcagtaga cacccgttta gaagcgttga ttcaaaaagc aatggatcgc gtgatggagg
    33721 gacggacaag tttcgtcatc gctcaccgtt tatcgacaat ccgtgatgca gatctgattc
    33781 tagtgatgga tcaaggtcag atcattgaaa aaggaacgca tgagagttta ttggcacaag
    33841 gtggatttta tgaaaaactg tataacagcc aatttgctga ggaagcagaa taagtcatat
    33901 aagaataaaa cagtttaaaa cttatttttt gttctctatt cttgataatg gtaaagtaaa
    33961 gttatcaaga aaagtgagga cacggagatg gaacagtttt taaatgaaaa aattactgaa
    34021 gccaaaagag aagttgatcg tttaacgcac gtctgtcaga cgaagccttt tgattcagct
    34081 gatttttttg aaaatgagtt tcaaatcgaa cgcttggcag cacaaataga agtgtacgaa
    34141 ttaattttaa aaaaagtaat agaagaaaat atagatgtac aataaaaaca ggtaaaacgt
    34201 cagttaccag atactgtaaa tagacatctg gcctgagcag gttttacctg ttttttttct
    34261 tatgaaataa atatatgcta tgataccttt attcaatagg attagtttct acaaaaaatg
    34321 aaaggagaaa aataaatatg gaacggttta tagcatcaaa tgccacagtg attggtgatg
    34381 tgacattgtc agaagatgtg acgatctggt atcaagctgt tttacgcggg gacagtaatt
    34441 ggataaaaat aggacaaaga acgaatatcc aagatggtac aatcatccat gtcgatcatg
    34501 atgcacctgt agatattgcg gagaatgtga cggtaggaca tcagtgcatg ctacatggct
    34561 gtacaatcga aaaaggggcg ctgatcggga tggggaccac gatattgaat catgcggtta
    34621 ttggtgagaa tagtttgatt ggtgctggat cattagtaac agaaggaaaa gttattcctc
    34681 ctaatgtctt ggcttttggt cgcccagcta aagtgatccg tcctttgaca aaagaagaaa
    34741 tacaaaaaaa caaagaaaac atccagcatt atgtcgagat aggtcggatg catgcgcaag
    34801 gaaaattcaa ggagcaaaga taggcagtag catccataaa ataaaaaagg atggtcagtt
    34861 tgagttgacc atcctttttt atttggttta gataagagag cttaaaaaag cttcctttga
    34921 aacagattaa tttaatgaag aactgttttc catgacttca tcgatcaatc catatgcttt
    34981 tgcttgttca gctgtcatat agttgtcacg atctgtatct ttttcaatca cttcaagcgg
    35041 ttgtccagtg cgttcagcta aaattttgtt taagcgttcg cgtgtttgca aaatatggcg
    35101 tgccgcaatt tcgatttcag ttgcttgccc ttgagcgccg ccaagaggtt gatggatcat
    35161 gatctcagca tttggtaaag caaatcgttt accttttgta ccagctgtca gcaagaagct
    35221 tcccattgaa gcagccatac ccataacaat tgtttggaca tctgctttga caaagttcat
    35281 tgtgtcgtaa atagccatac ctgctgtaac tgaaccacca ggagaattga tataaagata
    35341 gatatctttt tcagaatctt gagcgtctaa gaaaagcaat tgggcgatga tcgaattagc
    35401 aagatcatct gttacttggc cgcttaacat gatgatacgg tctttcaata aacgtgagta
    35461 gatatcgtaa gctctttcac ctcgtgaaga ttgttcaatg actgtaggaa ttaaattcat
    35521 aatagagttc ctccttgatt tcgtttagaa atagtgtacc ataatttagt ttctaatacc
    35581 taaaatgtag tatacatttt tggtcaaaaa aggtcaaata aaaaacttag gcaaattagt
    35641 cgcataaacc cgctttatgg tatgataagc agagaaacaa aacaaggagg aacaacagat
    35701 tgatagttgg tattactggc cttatcggag tgctgacagg tgctgtagtt gtctatatcg
    35761 gcatgatact gcaaatgcgt cacttggaaa ataaagaaca gcgtagacgt gaattggaat
    35821 tgaaagtcaa agaaatcgag acgctgaatc aattaaataa aaagatcaac gagatcttgc
    35881 aaaaacggac aacgctgatg gaagaatatg tcagctttga tgcatttgat gattgttata
    35941 tcacgattga cgattttgcg tatctccaat cattttcagc gcaaaatagt ttttatctgc
    36001 caaattatat tttagacgag ctatttaaga atatctccca tcgaaaagtg attttatctc
    36061 cagatgaaac aatgaagatt ggtggatatg cttataaagg cggacgcgtg attttagaga
    36121 attttacgga tagtctgact gaaatgatca atgaaaaaaa agctcagttg aagactatga
    36181 cgcgccagcc gattggtttc ttctcgaaag atgatgtttg gagctgatat tttgaagcat
    36241 tgccgttgca catgagagcg tggtaatgct ttcttttttt cttaatgata caatagaact
    36301 gaacggagtg aagaaagatg ttacaaatct atgcccatcg cggaagcagc ggcacccacc
    36361 cagaaaatac gcttcctgca tttgcagaag ctgtacgagt aggtgcagat ggtatcgaac
    36421 tagatgtcca tctaagcaaa gatggttatt tgatcgttat gcacgacgaa gaagtggacc
    36481 ggacgactaa cggtaaaggg ctgattcgag aaaaaacatt ggaagaactc aaaaaattga
    36541 atgcaggggg caaattcagc aaagaatttc cagcagctaa agttcctgaa ttgagagaag
    36601 tgttaggact gctcctccaa aaaaattacc gagggatgct aatgattgaa attaaaactg
    36661 atcagtatga atatcccggt atcgaagaaa aattagccga aacattaaaa agtagagatt
    36721 ggccttttca acatgcatat tgcagctttc atttggattc tttggaaaaa atcgcattac
    36781 tggaaccgga gatacagctg gacttattga tgagtacttc tgataaaaag atccaactag
    36841 cagcagaaac cccttatata gaaggagtac atccaaaaaa tacttggttg ttcgaacatc
    36901 cagtccaggc agctgatttt ccaaaagcaa ttcgtgcatg gacgattaac gatgaagaag
    36961 aaatggccaa atgtcaagaa ctcaaaatag atggaataat aactgatttt ccggagaaag
    37021 ctcttcggtg gaaacaatca acgaaaagta ggtaaaatat ggaaaaagta ttagtgatcg
    37081 tcggtccgac agcagtcggt aaaacagcgc taagtgtgga actcgcacaa ctatttggag
    37141 gagagatcat cagtggtgat tcattgcaaa tctataaaaa tctggatatc ggtacagcaa
    37201 aaatcaaaga agaagagatg aataatgttc cgcatcattt gattgatgtg atcgaaccta
    37261 ctcaacgtta ctcagccgct gattttcagc attcaggtcg acaattgatt accgagattg
    37321 cgaaccgagg gcacctacct atcatagctg gtggtacggg tctctatatc caatcccttc
    37381 tatatgatta tcagttagga gcgacagaag aagcgaatcc tgagattaga aaaaagtatg
    37441 aaacgttagc tgaaacaatt ggttcccaag cattatggaa tcagttgaaa gaaaaagacc
    37501 cggcagctgc tgagaaaatc cactggaaca atcaacgcaa agtgataaga gctctggaag
    37561 ttttagagac gacaggacat agtatcacgg cacctaaaga agagccaaag caattgtatg
    37621 attacctcat gattggatta gatacgaagc gtagtattct ttatgaacga atcaatcaaa
    37681 gagtcgattt gatgctagca gaaggtttag tagcagaagc gcgtaaggtg tatgagcttg
    37741 gagaagtcca ggccagtcaa ggtattggat ataaagaatt tttcccttat tttgaaggga
    37801 aagaaacatt ggaagaagca acagaacaag tcaaactaca ttcgagaaga tacgcgaaac
    37861 gtcagttgac gtggtttcgt aaccgtttgg atgcacagtg gtttgatctt ataagtgagc
    37921 caaatcaaaa aagtcagatt gagcaaacaa tcaaaaaatg gctggaggcg gaataaaatg
    37981 gaagaaaaag tgatcatcgt aggggtagaa accgaagcaa accagcgtta cttttcagag
    38041 tcaatggaag agctagttca gctgacgaat accgcatcag gagaagtcgt attcacaatt
    38101 acacaaaaga gaccacaagt ggatcggcaa acgattatcg gtaaagggaa attacaagaa
    38161 ttagttcaac aagcggatgc gcatgaagcg gatttgatca tctttaatca tgagctaact
    38221 ccgagacaga gccaactgat taccgatgct gttggtcttc cggtaattga tcgcgtgcag
    38281 cttatcttag atatttttgc gatgcgtgct cgttcgaaag aagggaagct gcaggttgaa
    38341 cttgctcagt tagaatacct gctgcctcgt ttagtagggc aagggaaaac attatctcgt
    38401 cttggcggtg ggatcggaac aagagggcca ggtgaaacaa agttagaaac agaccgccga
    38461 catatacgga ataaaatttt tgctgttaag aaagaattga aagaagtaga agctcatcga
    38521 gagcgcaatc gccaaaaaag aaaaaatagc gagatttttc agattggact tattggctac
    38581 acgaatgccg ggaagtcaac tatcttgaat ctattgacac aagcggatac ttattcgaaa
    38641 gatcaattgt ttgcaacgtt agatccattg actaagagat ggcgttttgc tgaaggattt
    38701 gagattactg taacggatac cgtcgggttc atccaagacc tgcctacgca actgatcgat
    38761 gctttccatt ctacattaga agaaagtcaa aatatggatc ttttgctaca tgtagtcgat
    38821 gctagttctc cagatcgtat tttacaggag cagactgtct taaaattgat ggatgaactg
    38881 aatatgaaag aaatgccgat actgactgtt tacaataagg cagaccagat cgacccagcg
    38941 atgttcacgc ctacgctatt cccaaatgta ttgatttcta ctcagacgaa agaaggtaag
    39001 atggcgttga tcgaagcaat caaacgtcag ctgatggaac taatgacccc ttatacactt
    39061 tctgtgccaa gcaacgaagg acagaaatta agcgagttga gaagacaaac aatggttttg
    39121 gacgaagcgt acatggaaga aacaaacgaa tatgaagtta aagggtttgc aaaaaccaat
    39181 tcaaaatggt taagaaaaaa ccaataaaat tttatttttt taa
//
LOCUS       DAFTHM010000015        39010 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFTHM010000015 DAFTHM010000000
VERSION     DAFTHM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39010
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.015"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..190)
                     /locus_tag="L7C88_000802"
     CDS             complement(<1..190)
                     /locus_tag="L7C88_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBP9557653.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVM"
     gene            complement(320..904)
                     /locus_tag="L7C88_000803"
     CDS             complement(320..904)
                     /locus_tag="L7C88_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBP9557654.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(1235..1468)
                     /locus_tag="L7C88_000804"
     CDS             complement(1235..1468)
                     /locus_tag="L7C88_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBP9557655.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(1483..2433)
                     /locus_tag="L7C88_000805"
     CDS             complement(1483..2433)
                     /locus_tag="L7C88_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBP9557656.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(2430..3272)
                     /locus_tag="L7C88_000806"
     CDS             complement(2430..3272)
                     /locus_tag="L7C88_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBP9557657.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(3274..3993)
                     /locus_tag="L7C88_000807"
     CDS             complement(3274..3993)
                     /locus_tag="L7C88_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBP9557658.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            4685..4843
                     /locus_tag="L7C88_000808"
     CDS             4685..4843
                     /locus_tag="L7C88_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557659.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            4915..6141
                     /locus_tag="L7C88_000809"
     CDS             4915..6141
                     /locus_tag="L7C88_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBP9557660.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(6229..6621)
                     /gene="rpsI"
                     /locus_tag="L7C88_000810"
     CDS             complement(6229..6621)
                     /gene="rpsI"
                     /locus_tag="L7C88_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBP9557661.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(6637..7080)
                     /gene="rplM"
                     /locus_tag="L7C88_000811"
     CDS             complement(6637..7080)
                     /gene="rplM"
                     /locus_tag="L7C88_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBP9557662.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(7599..8066)
                     /locus_tag="L7C88_000812"
     CDS             complement(7599..8066)
                     /locus_tag="L7C88_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBP9557663.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(8186..9724)
                     /locus_tag="L7C88_000813"
     CDS             complement(8186..9724)
                     /locus_tag="L7C88_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBP9557664.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            9804..10490
                     /locus_tag="L7C88_000814"
     CDS             9804..10490
                     /locus_tag="L7C88_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBP9557665.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(10691..11218)
                     /gene="msrA"
                     /locus_tag="L7C88_000815"
     CDS             complement(10691..11218)
                     /gene="msrA"
                     /locus_tag="L7C88_000815"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBP9557666.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(11302..11979)
                     /gene="pgmB"
                     /locus_tag="L7C88_000816"
     CDS             complement(11302..11979)
                     /gene="pgmB"
                     /locus_tag="L7C88_000816"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBP9557667.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(11976..13106)
                     /locus_tag="L7C88_000817"
     CDS             complement(11976..13106)
                     /locus_tag="L7C88_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBP9557668.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(13106..15289)
                     /locus_tag="L7C88_000818"
     CDS             complement(13106..15289)
                     /locus_tag="L7C88_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBP9557669.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(15286..16311)
                     /locus_tag="L7C88_000819"
     CDS             complement(15286..16311)
                     /locus_tag="L7C88_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBP9557670.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(16356..17183)
                     /locus_tag="L7C88_000820"
     CDS             complement(16356..17183)
                     /locus_tag="L7C88_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBP9557671.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(17180..18247)
                     /locus_tag="L7C88_000821"
     CDS             complement(17180..18247)
                     /locus_tag="L7C88_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBP9557672.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(18273..19109)
                     /locus_tag="L7C88_000822"
     CDS             complement(18273..19109)
                     /locus_tag="L7C88_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9557673.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(19106..19975)
                     /locus_tag="L7C88_000823"
     CDS             complement(19106..19975)
                     /locus_tag="L7C88_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9557674.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(20045..21328)
                     /locus_tag="L7C88_000824"
     CDS             complement(20045..21328)
                     /locus_tag="L7C88_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBP9557675.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(21342..23027)
                     /locus_tag="L7C88_000825"
     CDS             complement(21342..23027)
                     /locus_tag="L7C88_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBP9557676.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            23302..24327
                     /locus_tag="L7C88_000826"
     CDS             23302..24327
                     /locus_tag="L7C88_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9557677.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(24922..28596)
                     /gene="rpoC"
                     /locus_tag="L7C88_000827"
     CDS             complement(24922..28596)
                     /gene="rpoC"
                     /locus_tag="L7C88_000827"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBP9557678.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(28654..32271)
                     /gene="rpoB"
                     /locus_tag="L7C88_000828"
     CDS             complement(28654..32271)
                     /gene="rpoB"
                     /locus_tag="L7C88_000828"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBP9557679.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            32999..33967
                     /locus_tag="L7C88_000829"
     CDS             32999..33967
                     /locus_tag="L7C88_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBP9557680.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            33985..34890
                     /locus_tag="L7C88_000830"
     CDS             33985..34890
                     /locus_tag="L7C88_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557681.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            34887..35693
                     /locus_tag="L7C88_000831"
     CDS             34887..35693
                     /locus_tag="L7C88_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9557682.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            35829..36818
                     /locus_tag="L7C88_000832"
     CDS             35829..36818
                     /locus_tag="L7C88_000832"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBP9557683.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(37135..37659)
                     /locus_tag="L7C88_000833"
     CDS             complement(37135..37659)
                     /locus_tag="L7C88_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBP9557684.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            37946..>39010
                     /gene="scm"
                     /locus_tag="L7C88_000834"
     CDS             37946..>39010
                     /gene="scm"
                     /locus_tag="L7C88_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBP9557685.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        11403 a         8119 c         7015 g        12473 t
ORIGIN      
        1 tcattactaa aaacagaact gaataaatca agatgaaata aatacatgtc tttattttac
       61 gaaacatcaa tactaaaact gtagcaataa tgaaacaccc cacttgaaat atatttccct
      121 ttcctaaaaa aataatgacc ggaaaaaaaa tatttaaagt aatcaaggtt aacggattga
      181 tttttgacac tctttcacct ccaaaaaata agatcgcact gttatcttaa gctgataaaa
      241 atgcaccgtt attcagataa cagtgcgatc ttatcaaaaa gcataactga gaacaattct
      301 caatgcaagc tttttttaat taactcagta attcaatcca cccaggaaca gaaaattgat
      361 acaatcttct ggttaatagc atagtctttt cttttgaata gctatgcttc aatatatcat
      421 agaatgtagc gtagaatgag taaatgtaga agtggatttc ttcttcatta aagactaaat
      481 tttgattgat cattccgata gtctttaact tatctagaca acagactgtc tttttcgtca
      541 caaatgatgt aattttttca acaatatctt gatatttggt tccagctgat tggaataaaa
      601 tcaaatcgaa tatacgttta ttctcaaaaa tataattaat aaatggatct aattcattga
      661 agttctctct ccaacttttc tctatatcta tattttctaa gtttaagagg tatttggtaa
      721 actcttcatt atacatatta ataagcgcat taatatgcgg ctgaataatt tcttcaaata
      781 acgcttcctt agaagtaaaa tgtttataaa aagcacccgt agttacgcct gcggtcaggc
      841 acagttgcct tatcttagtt tgctgaaatc cttctttttc aaaatggctt agtccacttt
      901 ctattaactt ttggtgagtt ataatataat ctctggtttc tatgggtact tcctcctaat
      961 aagatgaatt aactttatta tcttacacag gacttgaagt ttcaatcgtt aacgtttatt
     1021 actgaactca ttccttagag ctaaactaat gagaaagagc agaataactg atacaaaaag
     1081 caatcctaca agaattaata gactcatcta aatcattcac cttttctaaa ataatccgag
     1141 aaagatttaa aaaaattata tccagctatt aggataagtc ctatcataat cactccaata
     1201 gccattttct tatcctccct aaaaataaag tcttttactt aaaacctttt ttgtaatcgt
     1261 caataaattt tttcccttta tcagttaatt gaaatcctat atctaaatag tcctcatatc
     1321 taagtttagc cagcatctca cttacagatg ctggactaac acttagaact tttgctaaat
     1381 cattattttt taatttcttt tttctttttg ataattcctg aattgctagt aaataaatta
     1441 gtatagtagt cgttttaatt tgtaccatac ctaccctcca aattatttcg aaaggccttc
     1501 agcaatttta tccaggttcc atttcatcat cgcatagtaa ctatcaccat cttgtccttt
     1561 ttctgcaatt gaatcagtaa aaatcgttga atagatagga atattggtat cttttgatac
     1621 tgttttcatt ggtctatcat ccacactgct ttctacgaat aaggagggaa cttttgttgt
     1681 gcgtaatttt tcaactaagt gttttatttg atctggtgtt ccttcttctt cagtgttgat
     1741 ttcccaaatg taagcagaag gcacattata cgctttcgag aaatatttaa agcatccttc
     1801 acttgtaaca atcatttttt tatcattcgg aattgaagca aatttagatt tagcttcttt
     1861 gtctagagaa tccaattttt caatatactt atctagattt tctttataga attttttatt
     1921 atcaggatct ttttccgcta actgtttttc aatattttta gcgtaaataa taccgttttc
     1981 taaatttaac caagcatgag gatcttcctt ccctttctca ctctgaccct ctaagtaaat
     2041 aacatctatg ccatcacttg ctgcaaaata gtctttgttt tcctctttgt tcgcattttt
     2101 aactaatttt gtaaaccaag catttcctcc agtttccaag ttaacaccgt tataaaaaat
     2161 caaatctgct tttgaagttt tttgaacatc ttcaggcaaa ggttcatatt cgtggggatc
     2221 tttcccaata ggtacgatac tgtgtaaatc aattttatct tttgctatat tttcggtaat
     2281 atctgctaaa atcgaattag taactactac ttttaatttt tcgttcgaag ccactttatc
     2341 tttgtcttta ctatttattg aacatgcccc gaatataaaa agagcaatca aaatccccag
     2401 acttcccagt actgctttcc attttctcat cataacgatc tctccttctt tcttaaaaat
     2461 ttttgttttg gtgagattag aaaactaatt acaaataaga atgccgctgt taaaacaata
     2521 cttgatcctg ctgctatgtt aaaactataa ccaataaaca atccaagcaa tgatgaactt
     2581 gctccgactg ttgcagaaat aaatatcata gttttcaagc tatttgcata taaatatgct
     2641 gtagctgctg gtgtaattaa cattgcaaca attaatatag ttcccacact ttgcatagct
     2701 gttactgcta ctaaagttaa tagaaccatc aatagataat gataaaaact gacattcatc
     2761 cctattgctt ttgccattaa tggatcaaaa gaagtgatta ataattcttt aaaaaataga
     2821 actactataa ccaacactaa aaccgaaacg ccaattgtaa tccacttatc aatatcttgt
     2881 acagctaaaa tatttccaaa taaaatatga aataaatccg ttgagctatt tgcaactcct
     2941 ataaggataa ctcctagtgc taaaaaagaa ctgaaagtaa taccaattgc tgtatctcct
     3001 tttattacac tattgctttt tataaaagta ataatgatag aagctaatag accaaataca
     3061 atcgcaccaa taaaaaaatt aatacctaaa atataagaaa ttgctactcc tggcaaaaca
     3121 gcatgagaaa tagcatcacc cataagagac attcctctta aaataataaa acaacctact
     3181 gttccagaaa caatccctat aactacagat gtaattagag cattctgtaa aaagtgaaag
     3241 tcatacagac cattaataaa attttgaagc atattattcc ccctctccaa taaatatagt
     3301 atctccatag gcttttttta aattttcttc attaaataca gattctacac ttccgtgagc
     3361 aattagattt cgattcaaaa gaataatatt atcaaaatac ttctttacct tgcttaaatc
     3421 atgatgcaca attagcactg tttttccctg atgtttcaat ttttttaacg tatccataat
     3481 tattcgttca ctaactaagt ctatccctac aaatggttca tctaaaaata tgaaatccgc
     3541 attttgagca agacatcttg ctaaaagtac acgttgaaat tgtcctccag ataattctcc
     3601 tatttgatga ttagaatatt ttcccatatc gaccttttcc aaagcctttg aaactctttg
     3661 ccattctgca tttttaattc tttgaaaaac tttcattccg gcatatgttc ccatagatac
     3721 acattctttt acttttattg gaaaagtaaa atcaatatca gctttttgct ctacatatgc
     3781 aatcttcacc agttttttat tgatatcttc attattaatg gagacctctc cctgatgagg
     3841 gataatattt aacattgctt taagcaatgt ggattttcca gcaccatttg gaccaataat
     3901 acctgttaaa gcaccttctt gtatttttaa agaaatctcg ttcaatgcta aaaaatcgtt
     3961 ataacaaaca ttaagctttt tcacttctaa cataactttc tccttctaaa tgataatgat
     4021 tatcacgatc atatggtata caaaaattat attttagtca accctaaatt ttatagttta
     4081 gatttttttc tgttgctgaa gattagaatg acaaaactat ttgaaactac gcgtatagta
     4141 agtagctttc aaaatatata aaaaaggagc gttctcaaat gagaacatgc tcctaaaact
     4201 actttattgg cgtatggaaa aattatactt gaagtggata gcgggttgaa taagttgata
     4261 agcatcaaaa catttataaa aattattcaa gactatgtct gttccatata caaatatgaa
     4321 aatcagtaaa ctccatttaa cttttttcgt agtgtgtctt tttatacatg tttatcgtta
     4381 ttaatagtga ataggaaaaa aactattttt gatcattgac aattaaatac aatttttgaa
     4441 taacgatccc tgctattcga gctagaaact caagtacgcc atgacctgat tagcgacaaa
     4501 tacttagaga tttctttttg ttctgggaaa acaaaatgcc atgacaatag cagcaaataa
     4561 tgatacttcc gtaaggctcg ccgtaaactg gggagaggtg aaattcctat gtgcttaccc
     4621 aaagcaattc aaaaatttca taactactat tttaggagat gattttatag aatccagagt
     4681 ctacctgaat aaaaaacaaa cctgtgcatt tctaggaatc gataataata ctctagataa
     4741 gtggattcgt atatataatt tcccagtaat aagagttggt ggtgtagttc gctttgacgt
     4801 agaagatatt aaagacttta tgaatacatt taaaataact tgaaattttc ttctcgccgc
     4861 atatactaaa attagtgaaa tatactgcct tacttttttt aaggagtgag gattttgcct
     4921 acaaagcttt caaatgggaa atataaaact aatctgagat atccaaaaag gtttaaagaa
     4981 ataacaggaa ttgcatcaga aaagtatcaa aaaacatttc caaataggca attggcgatt
     5041 aaagccgaaa atgatatgaa gaagaaaata gaaaaagttt tgagagagga gaatgcaaac
     5101 tcattagaat taaaaggaaa aataacgttt aaaaaatttt acgaatctaa atggcttcct
     5161 agatatgaat taggtcaaac aattagatca aacaggcctc ctagtgatat aaccattagt
     5221 aatacaaaag atatatttcg gttgcatatt ttacctatgt ttggtgaata cgcaatgaat
     5281 tatctaaata tcaatactga gataatatca gatgaattaa ccaaaaaatc gaaagaatat
     5341 gcaaatataa aaatcataaa aggatatgtt cgttccatgt tcgatattgc agaaatacta
     5401 aattatatcg aatttaatcg aactactaaa attattcaaa gtatcactgc acctaaaaaa
     5461 aatgctttag aagaaaaaag aatacaagaa ggtaagcaag cactatcatc aaaagaactt
     5521 actaattgga tagaagcagt aaatgatgat tttaataatc atttacttac ttttcatgat
     5581 tacacacttt ttatgattac cctgtatctt ggtgatagaa aaagtgagac ttacgctttg
     5641 caatggaaat atattgattt tgaaaaacaa acggtccgtc ttaaacatac tttagataaa
     5701 tatcaaagaa aaaagtttac aaaaggtcga aaagataccg tcattcaagt accagaagtt
     5761 gtaatgacat tgctaagtga atggaaatcg gtacaagctg atcaattgtt gaaattaaaa
     5821 attaagcaaa cgttagatca gtatctcttt acttatacta aaccatctgg agaagtaaat
     5881 tgtcctgttc atgccgatta cctaaactat cgaatcaatt caattaaaag aaggcatcct
     5941 gacttagttc atttatctcc acacaaactc cgtcatactt atgcaactat agctagacaa
     6001 ggtggagcag atatgaatca aatttcaaat gctttaacac actcagatat ttctacaaca
     6061 aagatatatg tgaacacacc agatatagtt gataaggctg tttttgaagc ttttcagaga
     6121 ggattgaata agtgtgattg atatgtgttc ttaaatgtgt tcttaaaaac aaaagaagca
     6181 ctttccaaat aattgaaaag tgccagaaac gttgatatat aaaggatatt aacgttttga
     6241 gaattgtgaa gctttacgtg ctttcttaag acctggtttt ttacgttcga ccatacgtgc
     6301 gtcacgagta agtaagccag cacgtttaag agctaaacgg aagtcaggat caacttctag
     6361 caatgcacga gcgataccat gacggatagc tcctgattgt ccagcgtatc ctccgccgtt
     6421 tacgttaaca aatacgtcat atgcgccttt tgtttcagta acagcgaaag gttgattgat
     6481 tacttcacgc aagtcagcat gtggaatgta ttcttcaaca tcttttttat ttacagtaat
     6541 tttgccagtt cctggtacta gacgtacgcg agcaactgcg tttttacgac ggcctgtgcc
     6601 gatatattga acttgtgcca atgaaattcc ctcctattag attaagtttg tgatgtctaa
     6661 aacttctggt tgttgtgctg catgtggatg ttctgctcca ccgtatacgt tcaattttgt
     6721 aaattgtttg cggcctaaag tgtttttagg aagcatacct tttacagaag tttcgatcaa
     6781 acgacgagaa tttttagcac gcaattcgcc agcagtgatt gatttcaatc ctcctgggta
     6841 gttgctgtga cggtaataaa ttttgtcagt cgctttttta cctgttaatt tcactttgtc
     6901 tgcattgatg acgatgacga aatcgccagt atccaaatga ggtgtgaaag ttggtttatt
     6961 tttaccacgt agtacagatg caacaactgt tgaaagacgt cccaatggaa catcagttgc
     7021 gtctactaca taccatttac gttctacttc gcctggtttg gccatatatg ttgtacgcac
     7081 gttattttcc tccaatttaa gttctgatgt ttgacataca cttcgagttt ccggggctct
     7141 ttgtggggca aacaatacca tttaacatat tacccgctaa tctagtcaat gtcaacgttt
     7201 ttctgcttga ttgaaaaatt tatatgaaac tttacttctt ttctttcttt tatataaaag
     7261 ggtcgtttcc tgtcaaaatg aaaaacaaaa agaggctgtg acaaaagtct tgtcacaacc
     7321 ccttattttg aataaacggt gttctcctgc caactcctcg gtcacaagtc acaatatcca
     7381 taaaacataa gaagctgttt tttaaaattg tttcttgtga ctcggagctg aacggcaggc
     7441 ttacaacctc ttggtaaacg gtgttcaatc agctgaccct cggtattagc tcaaaaaacg
     7501 gcaaaatatg aggaactatt ttgacgtttg tttctctaat actcaggtca aaacgctgat
     7561 ttcacaacct ctttttcggt caagttcaac aacagttttt acgcgtcgat ctctggcgct
     7621 ttgcccaaat gagcttggat catccagata cgtttttctg tggctgtttt gaattcgata
     7681 aagatatctt gtgttggatc gtcgccttct tctccagaaa cttcgattcc tttttggtaa
     7741 agatctgcta gataacgata gcctgcaaca agtgtttcca aacgttctgg aatagtacga
     7801 tcccagcggc caatttcatc agggattttt gtgttatctg caaattcacg caatgtagaa
     7861 taaggtgaac cgtctaatgt gatcaagcgt tcggatactt catctaactg agcgttcaaa
     7921 tcatccatga actcatccat cattgggtgc aatgtaagga aacctggtcc tctcatgtac
     7981 caatgtgttt ggtgaacaac aacagacatt tggcttagat ctgcaactaa ttgatttaat
     8041 acttctttgg tttgttggaa tttcatcttt cttgcctcct aacattttct tacacttaaa
     8101 ataatagtag actttcaatg aaaagtacaa caaaatcatt tacctgagaa cgattttcag
     8161 ttcgcttttt tatccgtaaa gccaatcatt tttcagaatc agctaattct tctcgcagtt
     8221 gagcaaattg ctgataagtc tgtgctaaat gcttttgtgt cgaaacaaat aatggataga
     8281 ttttctgata ttttttatga tcagtttctt gtactccaac ttgctctttc aattctatca
     8341 attcctgtgc ttcactgata ctttggatct ttccgatgct tctccagcct aaaatcacag
     8401 ctcctaatgc ggatgcttct gtgacagtag ggaaaacaag cgggtaaccc agtacatcag
     8461 ccatcatctg acgaaaaatc ggagattgag caaacccgcc tgtagcacgg atctctgtga
     8521 gctgattttc ctggcaaact ccttttaaaa tccgataaag gttgagacag atcccttcta
     8581 gaatcgcctt catcatttct ttttctgtat gttgccgctg taaaccgata aaactgccaa
     8641 acgcatctgc gtcccaaagc ggtgctcgct caccaagtaa atagggatga aaaatcagac
     8701 cattggcacc cgctggcaca aaagcgatag ccgaaagcag tgcatcatat ggattttctc
     8761 ctttttcttt agcagattga acgacttcct gtaaaaatgt atgccctgcc caatcaaaga
     8821 tgccagcacc attgctagtc gctcctccca ctacccaatg tttctgatcc agaacataac
     8881 aaaacgtctc catttctgga tggaactgag gctgagtagt aataaaacga agtgctccgc
     8941 tcgttcctac ggtcaaagcg gcgatcgtat caccaaaagc acctaaccct agattagaaa
     9001 gcggcccgtc tgcccctccc aaaacaaatg atatatcatt tggcaaacct agttctgctg
     9061 ctgtttttga tggtagacct gttacttgat aggtggaagg aaagacttgc ggcaattgct
     9121 ctattcgaat gttcaagtag tcaagcactt cttctgccca ttggaattca tggatatcaa
     9181 aatatccagt tcctgaagct gttccgtagt cgctgatcag ttcgccaaac aatctataaa
     9241 agatatagtc tttgataccg acaaaataag cagttttttt gaataattca ggttggctgt
     9301 tttgcagcca cttgattttg ttcaatggtg tcattggatg aatcggcgtc ccagtctgcc
     9361 gataaaattc tttgccaagc acggtatatt tcagtttttc tgcttcgtcc gctgctcggt
     9421 tatctgccca agtgatcatt cgagataacg gtgttttctc ttcatccaac aatatcaggc
     9481 catgcatcgc agaggagaag gagacaaatt gaatgattgt gtctgaaggc aactgtttaa
     9541 ttacttcttt tataacggtg cagacacctt gaaagatcaa ttcctgatct tgttctgcca
     9601 tcccttgtgt ttcttggatc aaagggtagc gaaaataagc ggatgctgct tcttgggctt
     9661 catctgtgaa agcaactgct ttggtttgtg tggttccgat atctaatccg attgaaacgt
     9721 tcattttttc acctcaaatt ttatgtatgt acaaaaattt agtttaagct tgcgtatctt
     9781 ggttttgaaa agggggagat ggcgtgttac tttattttat cattggttgc tgtatcggat
     9841 catttttatg tttaaccgcc cagcggattc cgttaggtca ctctattatt tatcctagat
     9901 ctcattgtgt caaatgctgt cgttcgcttt cttggtatga attgattccg attctctcga
     9961 tcatcgtcca acgatttcgc tgccgctatt gcaggtgtcg gttgcccttc tactatttgt
    10021 tggcagaagc cttatgtggt ggtctttttg cctggttctt tactttttct tccgcaagaa
    10081 atttttcgac gttcatatgg atgctttcgg ctttgctatt ttcgttgatg gatttatttt
    10141 acttcatggt ccattctcac acgctattct gttcttgggc aattttatgg attttttggt
    10201 tgcaggccgg cgtcttccaa tggcaaagtg tgctgttaac gtttatcgta ggcggtgtgt
    10261 gccttcgcta tggtcaatcc tatctcggag ctggcgatac tctgttgatg ctttcttgga
    10321 gtggtggctt gtctctagaa gagttgcttc agatcttgtt tcttgctagt ctgtttggaa
    10381 tatccgtttt ttctgtttac tttatctgtc ataaaaaaaa gttggaaaag ctgcctttca
    10441 ttcctttttt gagcagtgcg ttgctgattg tccttcatct taggtattga aaaaaggttg
    10501 tgacaaacga cttgtcacaa cctctgatat atagtgttct cttaccaaat ccttgtgact
    10561 tggagctagg cgacaggttc acaacctctc cactaaatgg tgttcaatca gctgaccctc
    10621 agtattagct caaaatgctg gttttacaac ctctgatata cggtgttcca taagtagctt
    10681 tttcggcttc ttatttcttg acgccccaat gtcgacgaag gaaacctgca cgtccagaac
    10741 cttctcgata aagattgtaa tggagcttgt ttttcttgta ataatcctga tggtaatctt
    10801 ctgcaggata aaattcgctt cttggttcga tttttgtcac gattggctta tcgaatcgcc
    10861 cgctgtcttg caatgcttgt tttgaacgct ctgcaatatt tcgttcttct tcatcattat
    10921 agtagatcac tggacgataa gaatcaccgc gatcagcgaa ctgtcctaat gcgtcagtcg
    10981 gatcggtttg ctgccaatag atttccacca actgatcata agaaataact tctggatcat
    11041 attcgatctc tactgcttct gtatgccctg ttgtgcctgt tgttacttgt tcataagttg
    11101 gatttggtac atgcccgcca gtataaccgg atgtcacaga aatgatccct ggctgctctt
    11161 caaatggttt gaccatacac caaaagcatc cgcctgcgaa aactgctttt tttgtcatat
    11221 aaaatccccc ttttttctca tcataccttg atttccaaaa ggaggataac gttttgcttg
    11281 tgacagaaaa aacggaaact attatatacg tgatacggct tctgataaat gccaaaacga
    11341 acgtacttga tcaaaaacgg ttaaatcagg aatcacatat tcagcagaag gaagatttat
    11401 gttttcacct attcccaata catgcatgtt accagccaaa gctgcttgac aaccagcttc
    11461 tgaatcttca atgaccaagc atgcatttgg cggtacattc aattgctgtg ctcctttgag
    11521 aaaaacttct ggatcaggtt ttgcttttga tacttgcgtg ccgtcaataa ggacatcaaa
    11581 ataacttgtc aaattcgttt tttctaaaat gaggcgtgca tttttgcttg ctgatcccaa
    11641 tccgatcttg atgtttgttt ttttcaagta ctcaagaaca gctattgcac caggcaaaac
    11701 ggatgtttca tccatttttt gaatcgcttg aagatataga ttgttttttt gctcagcaaa
    11761 ggctgatttc tctttttctg agaatttctg ttccattttt ccaaatgaca gcaatcgctc
    11821 tagtgactcg gttctggata ttcctttcag ttgctcgttt tctttctcag tgaatggaat
    11881 ggacagctgg ttagctaaaa ccagccacgc ttcgtaatga taacgagctg tgtctacaag
    11941 aacgccatct aaatcgaata gtgctgcttt gattttcatc gattacctcc ttgaaaatga
    12001 acgacttgaa gtaaagatgc gatgttttta gctgtgcgat gaagattatc agtggcttgc
    12061 tgtaaagctt cttgtaaagg cacagctgca ggaaggatcg gaaaaacggc cgaaatgcca
    12121 acatctgctg ctttttcgct tcctttacca acacttccgc aaatagctat cacaggaacg
    12181 ccctctggta ctcttctagc aatcccaact ggcgcttttc cttttagact ttgtccatct
    12241 agacgtcctt cgcctacgat tacgaggtct gcttgctgta cccgtttatc gaactccagt
    12301 aaatccaata cgtagtcgat gccagagact attttccctg aagcaaatgc taacagtcct
    12361 gcacccattc caccaccagc actactgccc gatgcctcga ttacttgagg ggcaaatctc
    12421 atataaaaat catgcatggc ttggtcagcc actgctaatt cattttcttt caagcctttt
    12481 tgtggtccga aaacaaaaga agcgccttct tttccgcata aaagattagt aacatcagta
    12541 atgacagtga ttttggcttt aatcagctca ataggcacgt tcgttttatc aactgtagca
    12601 attttaccta gattttctcc cagtgcttct actttttgat tatcttgatc gtaaaaagca
    12661 taacctagac cttctgccat gccgatgccg ccatcgttgg tactacttcc gccaacgccg
    12721 atgatgatgt gtcgaacacc ttgttgcaac aattgtcgta tcagttctcc tactcctcgc
    12781 gtggataacc taagtggctg ttgttggttt agtgggacat ctttcaatcc gacgatttct
    12841 gccatttcaa aaatcgcagt ttgaccgtct gaagcgtact ggatttcttt gtttttgcca
    12901 aatgcattag taacgactgc tgtttgccgc ttcaacctta aactgtctgc taatgatgaa
    12961 accgttcctt ctcctccatc gcctataggt agcagatcat attcagcctg aacaaaaact
    13021 tcttgaaaac ctgattgaat ggcttgtgct gcctctaagg ctgtcagact ttctttgaaa
    13081 gaatctggcg caatcagaat acgcattatt ttcccctccg ttccaagatc agttcttttt
    13141 ccagctggta ttggtctcca ttgacaaaaa taggtaatgt ttctttcgtc tcttttttta
    13201 ttactatttg tttttttgtc aaaacaaata gcaacctgtg atttttccaa ataaaaggaa
    13261 aagaaatttt ttcccatgct gaaggaagtc ttggagaaat agaaagagtt ccattcgtta
    13321 ctgtaatacc tgaaaaacca aatataactg ctagccatag tgctcctaat gaagcagcat
    13381 gaattccgtc atctgatgaa tgcggatctg gtcctaaatc aatcaggcac gcttcttgga
    13441 ataaatgata cgcccattcc atttcttgga tacggcaagc ctctatggcg tgaatcgctt
    13501 tactcaacga tgagtcgtgg attgttttgt tttcatagta atgcaaattc ttagaaacga
    13561 ttggttgaga aaaatactca ggtaataagt ataacagcat gacaagatct gcttgcttgc
    13621 tgacttggag ttcatttact tcgctacggg cataatcaag taaaatagac tggctgccag
    13681 gacgttcttt gtaagtggtc aaatcaataa ctggcttact gagatacgtg tcatcttgcg
    13741 gaatcagctg ttctttgtta ggcactggca aatataactt atctaaaaaa ttttgacatt
    13801 ctttcaaaaa aagcggatcg ccagcttgat atttaacagc taaggccaca ttataatgcg
    13861 ccagatagtt cgtatatgca ttattgtcga tatattctgt gtattcatct ggaccaatga
    13921 ctctgtgtat ctctaaatga tcatcgactt ttacagctct gctcagccaa aaagctgctg
    13981 tttcatgaat gagcgttttt ccctttgttt ctaaaaacga ttgatcctct gttgcttgga
    14041 catactcttg aacggcataa gcaaggtctg cactgatatg atgttctgcg gcagctgaag
    14101 caacttcttg tcttgttccg gttttgatat tcaatgcagc aaatttgggt gtctcttcct
    14161 gaccagtgtg tgcgctttcc catgggaaaa gtgcaccttg atagtgataa tctcttgctt
    14221 tttgccgtgc gccttctaat cgatcataac ggtacagcag caaattcttt gctacttcag
    14281 gaaactgata taaaaagaaa ggcaggataa aaatttccgt atcccagaaa acatgccctt
    14341 tataaccttc gccagttagt cccttcgccc ctacactaac acttggatca ttgcggggag
    14401 tcataatctg taaatggtaa gcagcgaagt ccatcgctaa ctgatcgaaa gaagaatcgc
    14461 cttggatcgt tatccgatgc tgatgccaaa aatctgtcca ataagacatc gactgctcta
    14521 aaatttctgt ataactaacg cttttctggg cttgggcaat acttttctta aacgggtctg
    14581 tttgctgaag agaggtagag agcacgatga tcttctccag cgtaaaggac gtattttttc
    14641 tgatcttttc tgaaaaggaa gcggtgatcc ggcgattttt tgcttggaat acacctgctt
    14701 tattgaattt agctgcaatc ccaatatcaa ttttactttc tgttgtctgg taggatgcac
    14761 tgatcaaatc gtcaccaaat actcgcagtt ctttttcaac caactgctgt gtaccaaaat
    14821 tggtttgctg tccatcgata cccgttttca catctacttg gcagtcttcg gtcaacggct
    14881 tgatgaccac tttcagggct gcctgatgga gattattttg atcagcaaca cgacaagtaa
    14941 tgacttccac tttttttcct tgagcagttt caatgagcgc atagcgttta agctctccca
    15001 tttctaaatc tagtgcccgc tcgtatgcaa gaactttcat cgtctcaaga gaaaaatgtt
    15061 caccgtcgat ttttatttcc catctgatga catctgggag attcactaac tcggctgatt
    15121 ctgctcctaa aggtcggtta tatacaccag ctgcaaacat tccccttact tgattccgat
    15181 agtcttcctc ctggcttcct ctgataccaa aaaatccatt tccaatggtc atctgactcg
    15241 catacttatt gatatactct aaatcaaact gtttttcttc tactttcata aggtaataac
    15301 ttctcctgtt tctgccgaac gatataaatt ttccaccaga ttctggatga catatccttg
    15361 ccagccatct gcaatcatct gagtctggtc accgagcgcc cgattcacaa aatgagccat
    15421 acttagttca tgtgggtcat taactggcgt ggtcttttgt aaggaaacca gctttccatc
    15481 tacatcttcg aatagttcgc ctggatacag attagcacct gcctgatcgc cacaaaaagc
    15541 cacattcagt ttgtcttctc tgatattcaa agcaaacgaa gtattcagtt ggatgatctt
    15601 gccgttttct aattccagtg tgccaaaaat tgcatcttct actgtgaatt tgcttggatc
    15661 ccatttcccg aatttccctg aatttttttt cgtaccaatt ttttggaagc tgtacgcccg
    15721 aacgcttttt actttaggaa atccagtaat atacatcgct gtatcaagca tgtgaatgcc
    15781 ataatcgatc aaaggcccgc ctccttgaag ttctttgtcg ataaacgttc cccagcctgg
    15841 aacaccagac cgacgaagcg cattcgcttc tacgtaataa atatccccga gaacatcaag
    15901 atgattcttg atcattgttg cttcgtcaga aaaacgatgc tggaatccat aagccaaaat
    15961 ctgcccgttt ttatcggctg tctctgccat ctttcttgct tgatcagctg tcatagctgg
    16021 tggtttctcg cacatcactg aagcattagc ttcgagggca gccaatacat gttcgaagtg
    16081 aaagcgattg ggtgtacaga cactcacgat atcgggagaa atctcattca gcatttgtgt
    16141 aactgatgta tacgcatgag aaaatcctgt acgtcggcaa aagtcttctg ctcgctggct
    16201 gactggatca accacagcgg ccaattctaa gacatctgat cttttttgat aataagcagc
    16261 atgtactttt tctgctactt gtccagcgcc tatgattgct actttcttca tttatttctc
    16321 tctcctttgc ttatttactt attgttattc tttctctatt ctttctctaa atcatttaaa
    16381 tgacgcgctg tttccagaca gtttttcaag tattgcaatg attcctgata aattttcact
    16441 tcattttctc ctcgcaaacg acattcatat accatataac cttcatactc attttgaagt
    16501 agcgtttgaa aatggcgagt aaaatcaatt gcgccagatc ctggttggta gcgatgatta
    16561 tctgctaaat ggatatgacc cacatactct ttttgcgtag tcaatgcttt tgaaatatca
    16621 tcttcttcaa tattcatatg ataaaaatca gcgatgatct gcacatgttt caattgatta
    16681 gagtcaatgt aatgacgcgc atccgctaac aaattgatca tatggtcttg gtatcggttc
    16741 aaaggctcca aataaataac cgtacctgtt tcttcggcta ctttatctaa ataacgaagt
    16801 gattcgctga ctgctttata gtctccttct ttgcttcggg gtgaaaccat cggcggtaat
    16861 cgataagtga acattcccca agctgctggg ataacgattc ctttgcctcc aacctcgctt
    16921 agtgcacgca aaatctcagc aatttgacgt acaccattaa gacgccgttc ttcgataaag
    16981 tcaccgatcc acccatcgta gccgttacaa gctgtcacta ctgggatccc tgtttctttg
    17041 attgcctgtt tgactgtgtc gatattttct attaacaact taccgtcgat ttcgtattct
    17101 tcaaatccac agtctttgat aaatctaaat ttttctaaaa tgtctcttgg gaaaaatgct
    17161 tgatcttgcg taccgaattt cattgttctc ctcctcggac ttgaacgccc attttgatac
    17221 tttcttctgg gtgctggtct acataacgca tgtaagcttc tgcgctttct gcaaatggca
    17281 caactggatc aatgatttct tcacaatcca agtaaccgtt catcaataat tcccaacatg
    17341 tgtcctcgat tcgtttacgg ttccatcttg ggtaatctgg gtttggttca ctagatgctc
    17401 gagcaaagac gatttttgca ttattgaaat gtgcttcgcg accaagatta aacccagctg
    17461 gaaaaggttt agcaaaggca acataagaaa tgatcccgcc atagccgatc cctattaaag
    17521 aagcttgtaa tgcggcagca ctgccactcg tttcaataac tgaatctact ccacgtttat
    17581 ctgtcaattc ctttagacga aaaccgacat ctgctttcat aggatctagc gtgtaatcgg
    17641 caccgtgttt ttctgctaat tctctacgct gcgctatggg atcgatccca acgatggtag
    17701 tagcacctgc ttttttagct aattgaatcg caatttgccc gatagcgcct aaaccgaaga
    17761 ttgctacagc atcacctgct cgaacatgtg cttcccggat accacctaaa gcgaattgag
    17821 caggatcgta acatactgca tttttccatt gatccaaccg atcaagttta cgtagtttat
    17881 aattatcaac accgtttgta atcagcgttt cacgaatggg tccataagtg cagactaact
    17941 ctcctttttg atactctgtc accaaactgc ccgtttcttc gatcgtaccg acaatcatat
    18001 ttcctaattg aaattcgcca aataccacac cgcgttggct tccttcttct cttggcaaga
    18061 ataggcgcca ttcttctgaa aattcttcat cgataaatgg acttaatcct ctaaagtcga
    18121 caatttctgt tcctggtttt ggagtagcga aaattactcg gatacgtact tcgttctttt
    18181 cgatctcacg gtcttcgtaa tctttgaatc cggctattct tggttctaat gcaactaatt
    18241 ttttcatctt ttctttcctc tttcttttct ttttatcctt ttacgccgcc ttcgactaaa
    18301 tcacctttaa taaatcgttc agataacgca tacataatga tgactggtaa agcggtcacc
    18361 aatgaagcgg ccatcattcg tccccaaatg tagtctggtg tactgaataa tgtgttcaaa
    18421 ccgattggta aagtaaattt ttcggaggtc gacaggaaaa tcgaagcaaa taaataatca
    18481 ttccacgaaa ccataaagca ataaacgaag acagaaatga ttccagaaat agccaatggt
    18541 ataatgatcc gaataatgat ctggatccgg ctaagaccat cgatcattgc tgcttcttca
    18601 atatcagtcg gaatcgtgtc aaaataactt tttagcatga atatcgcagt aggaagtgtt
    18661 tgaacgacca tcgtgataat cagtgctgta ttggtatcat acaaacctag accggaaatg
    18721 attttaaata atggaacaac gatcaaaata ccggaaaaca tataaacggt gtaaaagcta
    18781 gcattgattt tcgagcgagc tttgaagcgt agttttgaca aagcgtatgc cccgctgatc
    18841 ccaatcacta ctgcagttac ggaggctatc aaggagatca ctaaactatt tttgaaatac
    18901 atgatgaatg gaaaaatctc agcattgaaa atatcctgat aatgttcaaa agtccattct
    18961 ttcggaaaaa tagtttgtgt cgttgcaatt gcttcttgtg aatccttgaa tgatgtcatc
    19021 agcatgatca aaaatggaaa caaattgaca gctaatagca acaaaatcgt cgcgtaaaat
    19081 aagattttcc tgctcttttt atttttcatt tcaagtccac cttctttcgt gagagcaaga
    19141 cgaccgctgc aataatgatg aacaatagaa tcgatatagc tgctgctttt ccaagatcat
    19201 tgaacgcaaa ggctgtctga tacaaataaa cgcctaagat attgacttta ttcgtcagta
    19261 gatagacatc tgtaaacata tagaacatcc agatagatcg taaaacaatc acagttgcta
    19321 gtactggttt gattgccggc agtgtcacga tcttgaactt ctgccaagca tttgcaccgt
    19381 ccatttcagc tgcttcataa agcgttttgt cgactgtttg caaaatagcc aaaaatgaaa
    19441 taaacgcata cggatagtat ctccagatag caaacaaaac gaccataaag aagctagcaa
    19501 ctggctggtc gaaccacagc ggtgcttcgt tgaaaagctg caacctatct actaacagat
    19561 cattgacgat tccataacta ttattgaaca tatatttcca agcaaaaatc aaagaaatag
    19621 atggcgtaac ataacttaat aaaatcagtg aacgcaccgt tttcctaaat ctgaacttgc
    19681 ggttaagcaa aatagctacg gctaatccta aagctgtact gcctgctaca actaagaatg
    19741 tgtaagcaac tgttaaacct aaagaacgat aaaattcact atcacttaaa atttcaagat
    19801 aattgcttaa tccgataaaa acggcgtctg agttaggatt cagcggcata tcgaaaaaac
    19861 tgatctgaat attggaaagc attggaatca gcactaaaac agctaataaa agcatgcttg
    19921 gtgctaaaag tcccatggct aattttaagt cagaatgttt ccttggacga ttcattgaaa
    19981 cctccccctg ataatctgcc aatagctatc tacttttttc gaacaccatt ggcagaactt
    20041 cttgttattt cgtatttttt tgtgcgtcag ctaaagcttg atcgacatct tcgtttccga
    20101 cagttacttg gttcactgct tttccgatca cacctgagct tgtgatatct cccattttcg
    20161 tgaaattctt ttccccgact agtccaaaga cttgtacttc atcaaaagca ctagcaatct
    20221 cagatggcag ctcgccaaaa gacttgatga cttcattttc tttgtaacca tccagttcga
    20281 ctacttgttt attcactggt tgagcaccac caggagacat caagacccac ttttccatgt
    20341 ttttcggttg agataagaaa gctgtgaatg cttcagcagc ctctttttgt ttctcgtcta
    20401 gaccagaaga aatcgtcaat ccagatactg tgccatagac agcttgatct ttttgtgttg
    20461 ggatagcaaa accgatattt tctgagttcc ccgcttcata aacagaaggc aaaatgtaag
    20521 ttgaatagat tgccattggt gctgttccat tcatgaaagc atctttgatt tctgtcacat
    20581 cattagagcc tggcatcgtg tattgggata agttttgata aaacgacaat gcttctctca
    20641 tcttttccgt atcgatcgtt acctcgcctt catcatccaa aacatttgct ccatttgaca
    20701 aagcaaattg agagaacgct tgctcactca ttgttccttc agcagtaggc atagcaattc
    20761 catattgttt attctcttta tctgtgaaat gttgagcaat ttttaaaata tcatcccaat
    20821 tttctggttc tgaaaaacca gcttctgata atttttcttt gtcataccaa ataccttgaa
    20881 cccagccgct aattggtgca gcaatatagc tttttccatc ttctgaacga acaaggtttt
    20941 tggctccgtc ataataatta tcttctccag cttcctcgat aacgttttgg actgccgtct
    21001 gatcaatcag ttcatcttta tccatcactt tagcaaaatc ctgactgact tccattactt
    21061 ctggtaattt accggaacga gctaacgtaa cgatttttgt attgaacgct gattcttcta
    21121 ccggcacttg cttgattttg atgtctggat tttctttttc aaaatcagca accagttcat
    21181 tgatcacact taatcgttcc tgttcgacag aagagtgcat gaattgaatc gttgtctgtt
    21241 gtgattcgtt agagctttga ctttcaccac aagcagtaag aagaaatcca gtagctagca
    21301 gacaggtagt aacaataatt tttttcattt ttttccacct cttattttat tattttcagc
    21361 cacatatatt catacggctg gaatatcaac tttcgttctt gactgcaatg gataatttgt
    21421 ccagaaaaca ggtctaggta atctcctttt ggtaaaagat aacctgctga ttgattggaa
    21481 aaattatgga taactaagac tttctcttcc ttcgcttcgc gaataaaact gataaaagaa
    21541 tctgctgagt ccagtaagta aatcaaacta ttcggatgga aggctttttc tttttttcga
    21601 atagatagca tctgggtcaa ttcaccatat actgctgttc ttaatggatc tgtctgcaac
    21661 tctttctcaa tatctgctaa caaaaatttt tgccgattga tttttcgatt ctctcctgtt
    21721 ttttctacgc ctttgtaatc atttcgactt cccagcacac tttgaatata aattgccggc
    21781 acgcctggta acgttaccaa aaatgaatga gcagctaaaa agcgtttgct tctccattcc
    21841 gtcgtatctg ttggagaact taacgcatct agatacgtag cgtttatctc atatggactg
    21901 gtcgttccat ctgggttttt cttgtagttt actcgggcac cctctttctt cagctgttcc
    21961 actaattcaa ggatcgtttt ttccggcaga atacctcgta ccggattcaa tccgataccg
    22021 tcatgggagg ctaaaaaatt aaaaaaagtt gtttttttcg atgcgaaatc gatggttttt
    22081 aaccattctt tcaacttact tgtattaccc gaacgaatcg cttgaagggt caaaggtggt
    22141 agcgaaaact gatagaccat ctgtgcttca ttctcgccat tcccaaaata actgatatta
    22201 tctttgtgtg gcacatttgt ctcagtgatc aataccgttc ctggagctgc ttcatcagcg
    22261 attgcacgga ataattggat gattttatgc gtttctggca ggtgtataca agaagttcct
    22321 agttctttcc ataaaaatcc cacagcgtcc aagcgaataa atgaagcgcc tttttctaag
    22381 taaaacaaaa gaatatcgat cattttcaat aaaacttctg gatttttaaa attcaagtct
    22441 acttgatctt cgctaaaagt cgtccatacg tgtttttctt tcccgttttt gtcaatgaac
    22501 gttgtaagta acgggctggt ccttggtcta gtcacgctgc ttgtatctgt atccagtggc
    22561 aaatcaataa aaaaatcttt gtacgtatca ttcaagttta aatattcctg aaaccaagta
    22621 ctttcggcag acatatgatt gcagacaaag tcgaacatta accgtgtttc gcttctcatt
    22681 tcttctatat cttcccatgt gcccaaacgg tcgttgattg cctgataatt tacaacggag
    22741 aaaccatcat cagatgtata tgggaaaaat ggcaagaaat gtacaactct aaatgtatct
    22801 gccaaatact tttgataaaa tttcttaaat gtacgcaaag ttggttgctg ctcttcaaaa
    22861 aattgatccc cataagtaat caagaaaata tcttcttcgt cccaatgcag tttgcctgcc
    22921 tggcctttct tctgctgata aacactgact ttttgttcaa tcatagaggc ggttttctca
    22981 gacaaatctg agtcgcgata aatcgcttgt aaaagttttg tatacatcgg attccccttt
    23041 cttttttggg agcgttccca acgatttgat catattatgg aaaacgctta ctgtcaatag
    23101 cattttttta aataattttg atatacacaa aaatacaaat aagaaagctt atgtatcaat
    23161 aattaatagc ttcttaaaaa aatatggtct ctcatgatca tgcaagctat tcctaaattt
    23221 tcaaaatcat agacaaaaaa gaatgtctat tgtactatgg aattattcta aaacgctccc
    23281 aaaaaggagg tgcatataaa attgaaacct actatttatg acattgcgaa aaaagctaat
    23341 gtctcaaaat caactgtctc cagagtatta aataaccagc caaatatctc tgataaagca
    23401 aaagcaagtg tacttcaagc aatcaaagaa ttgaattatg aaccgagcaa aattgcaaga
    23461 ggactgtcag gaaatggttt tgacgcgatt ctagcattat ctcatcgtac ttctcatacg
    23521 acctatggca atcctttttt ttcagatgtt attcaatcca tttctgccgt ttctgaacaa
    23581 aataacttcg acttgattct acaaacggca aaaacaccag aagaagagct agaaaaatgc
    23641 gcgaaaaaga tccaagaaaa aatgatccga ggaattatta ttttaagctc tacgatggat
    23701 gaaacacttc tttttgaatt ggatcaatat aatattccta ttgtggtaat cggaaaagtc
    23761 ggaaacgact acacgaacat ctactcagtg gacacggata atttccagga tagttacgat
    23821 ttggtggaaa cactgatcaa gaatggacac cgtcatatcg gctgtctcca tgctccgaca
    23881 gaagtttatg tatccaatga tcgtctcaat ggttaccgtc aatgcttatt tgatcaccac
    23941 ctagatatcc gtaatgaatg gattatagac ggcggctttc gcttagaaga tagcatggca
    24001 gcaatgaatg atttaatgaa gctacgagaa agaccaactg cgattttttc taccgatgca
    24061 ttaaaatcat tgagtattta caaagtggca gaacaatctg gaaagcagat acctgatgat
    24121 ctttcgatcg caggattcag tgatccctta ttgtcctccc tattttcgcc acagttgact
    24181 cggatagaca ttccgacaaa tcagttagga atcaaagcca cagaactttt attccaacta
    24241 atccaccacc aataccctga agaaaaaaga atcattcttt caaccgagat tactctcaca
    24301 gattcgatcc aacaacaaga aatgtagaac agaattataa aagaacagaa acactgagga
    24361 taagtcagtt actctgttct tttttcaatc actcatccct cgttaccccc tcccggtatt
    24421 ttagcgaatt tttcttattt tccatctgtt ttagatagct gtggataact ataatgtttg
    24481 tgttaaacta ttttttccac agggaagaaa aaactatttt taaccacgtt gtgtataagt
    24541 ttttatagtt cgttttttta aacacattta cccttatttc aatccatgtt atttggggat
    24601 acttatctct aaaacataaa tagaataaca gacatgtcta ctggttttgt tttattcgag
    24661 gaattattca ataatagcta gcaaaatatt aaaaataacc gctctatctt cccatcaatt
    24721 tattttgcat tcaaaaaatg atctatcttt acttttgttg attgacttct cttggaagat
    24781 gatcgttccg ataccttaat tggatacgaa ccgatgttgt taagatcctt tcccactttt
    24841 cttctagtta gacaaattat tttagacaaa ccaaaaaaga ggttgtgaca ataatttgtc
    24901 acaacctctt ttttaaaata tctattttgt ttgattgttc attgcgtctt ctgcagccat
    24961 ttgcgcttca atatctgaaa tactgtagac attttcgctt gctacaccga cttcttttgg
    25021 ttccatgtca cgataacgtt gcataccagt accagctggg atgatcttac ctataataac
    25081 attttctttc aaaccaagaa gaggatcttt cttaccgcgg atcgcagcat ccgtcaagac
    25141 acgagttgtt tcttggaatg atgcagcaga taagaaacta tttgtttcta atgatgcttt
    25201 tgtgatacct agtaagacag gtcgagaagt tgcaggaacg cctcctgaga ctagcgtatt
    25261 gtagttttga tctttaaagt ctgcgatgtc taataatgta cctggtaaga tatctgtatc
    25321 acctggatcc attacacgaa ctttacgcag catttgacga accattactt cgatatgctt
    25381 gtcgccgatt tctacccctt gcatacggta aacacgttgt acttcacgaa gcaagtagtt
    25441 ttcaacagat aatacatcgc gaacttgcaa caattgtttt ggatcgattg atccttctgt
    25501 caatggtgca ccacggtgga tcatatcgcc ttctgctact ttcatacgtg ctgtataagg
    25561 aacagtatac gtacgtgtat ctgtttttcc tttgattgtt acttctttgg tacgtgttgc
    25621 aggatcttct gagatatcga tgacatcccc tgttacttct gtgatcactg cttgcccttt
    25681 cggattacgt gcttcaaaga tttcttggac acgaggaaga ccttgagtga tatcgtctcc
    25741 ggcaacccca cctgtatgga atgtacgcat cgtcaactga gtaccaggtt caccgattga
    25801 ttgagcggcg atcgtaccaa ctgcttctcc gacttcaacg tcagagccag ttgcaaggtt
    25861 gcgtccgtaa caatgtttgc agacaccatg ttttgtatta catgtgaaga cagaacggat
    25921 tgtcactgtt tcgacacctg catcaacgat ttgttttgcg atgtcttcgg aaatcaattg
    25981 gtttcctgca atgatcaatt catttgtttc aggatgacgt acttctttac gggtgtaacg
    26041 tcccactaaa cgatcttcta atgattcgat gatttcattt ccctcgcgga tggcttggat
    26101 ttcaagacct cggtcagtac cgcaatcttc ttcacggatg attacatctt gggccacgtc
    26161 aaccagacga cgagtcaagt aacctgaatc ggcagtcttc aaggctgtat cggtcatccc
    26221 tttacgagcc ccgtgagttg agataaacat ttccaagacg gatagtcctt cacggaagtt
    26281 cgaaatgatt ggcaattcca tgattcgacc attaggagcg gccatcaaac cacgcattcc
    26341 ggcaagctgt gtaaagttgg aaatgttacc acgagctcca gaatcagaca tcatgaagat
    26401 tggatttttc gcttccaaac cttccatcag tttttgttgg atgctgtctt ttgcagcatt
    26461 ccaaacagca atgacacgtt cataacgttc gtcatctgtg atcagaccac gacggaattg
    26521 ttttgtaata gtttcaactt gtttatgggc attttcaatg atttcttgtt tttcattcag
    26581 tacactgatg tcagcgatcc ctactgtgat accggcatgt gtcgaatgtt tgtaccctaa
    26641 gtctttcata cggtcaagca tcttagaagt ttctgttact ttgaatcgtt tgaagacttc
    26701 tgcgatgatg tttcctaagt ttttcttctt gaacggtaat actaattctt gctctttgat
    26761 atgtgcagga atatcagtac cagcttcaac aaagtatttg tccggtgttt ggacggtcaa
    26821 gttgaagtct gttggttcat tcagataagg gaattcagga ggcatgatct cgttgaagat
    26881 gatcttacca actgttgtga tcatcgtacg ttctttttgc cattcagtaa atggtttttc
    26941 acctaatgag ttagggttca caccgatacg tgaatgtaaa tgaacatatc cgttgcgcca
    27001 tgcgataacg gcttcgtttt gatctctgaa gaccattcct tcgccttcgc gtccttcttc
    27061 ttccattgtc aagtagtagt tacctagaac catatcttga gaaggagtaa caactggttt
    27121 accatcttta gggttcaaga tgttttgagc agctaacatc aacatacgtg cttctgcttg
    27181 tgcttcttca ttcaatggaa cgtggacagc catttggtct ccatcgaaat cggcattata
    27241 agcttcacat acaagtggat gcaaacggat tgcgcgtcct tgtactaaaa ctggttcgaa
    27301 tgcttggata ccaagtcggt gaagcgtagg tgcccggttc agcaatactg ggtgttcctt
    27361 gattacgtct tctaaaacat cccatacttc gtcttcttga cgttcgattt tacgtttcgc
    27421 atttttgatg tttgaagcta gttcgcgttg aacaagctca cgcatcacga atggtttgaa
    27481 taattcaatg gccatttctt ttggaagtcc acattggtac atcttcaaga aaggtccaac
    27541 aacgataacg gaacgacctg agtagtcgac acgtttacct agcaagtttt gacggaaacg
    27601 accttgtttc cctttcaaca tatgagaaag agatttcaat gggcggttac ctggtccagt
    27661 aactggacgt ccgcgacgac cgttatcgat caatgcatct actgcttctt gcagcatacg
    27721 tttttcattt tgaacgatga ttccaggtgc attcaagtct aacaaacgtt tcaaacggtt
    27781 attacggttg attacacgac ggtaaagatc attcaagtca cttgttgcaa aacgtccacc
    27841 ttctaattga accattgggc gtaaatctgg tggaataaca gggataacgt ccataaccat
    27901 ccagcttggt tgatttcctg aagcgcggaa tgcttctaaa atatccaaac ggcggattgc
    27961 acgtgtacgt ttttgtcctt gtgcagattt caattcttct ttcaattcgg ctgcttctgc
    28021 atctagatca acattatcaa gtaattgttt aatcgcttct gcacccatag cagcttggaa
    28081 ttcttgtcca tattgttcac gtttttcgcg atattcgcgt tctgtcaaca attgtttttt
    28141 ctctaaattc gtatttcctg gttcgatgac tacatatgaa gcaaaataaa tgatttcttc
    28201 caaagcgcgt gggctcatgt ctaatacaag acccatacgt gaaggaatcc ctttaaagta
    28261 ccagatatgt gaaacaggag ctgctaattc aatatgtccc atgcgttcac ggcgaacttt
    28321 cgaacgagta acttccactc cgcatcgatc acaaacgatt cctttataac ggatacgttt
    28381 gtattttccg caggcacatt cccagtcttt tgtaggacca aaaatccgct cacagaacaa
    28441 cccttcacgt tcaggtttta aggtacgata gttaatcgtc tcaggttttt ttacttcacc
    28501 gtaagaccag cttctgattt tttcgggaga agccaaacct atttgcatac tttcgaattt
    28561 atttacatcg atcaaaaggg gttccctcca tttcatttaa tggcaaaccg caagacggct
    28621 gatcttcgac cgccttgcag ctcatagacc ggattagtct aaattatctt ctgcggtttc
    28681 aaagttttgg atgacatcgt ctttttcatc ttccacttgt tcagcagctt tcttttctaa
    28741 ttctttggca gtttgctgtt cggcaaattt tgtcaaagca tcaacagtga tcaaatcgtc
    28801 gtcttcatcg tccatgtcgc gaagttcgat ctctgtttct tcgatatcca agacacgcat
    28861 gtccagacct agtgattgca attctttcac caatacgcgg aatgattccg gtacacctgg
    28921 ttttggaatt ggttcaccct tgacgattgc ttcgtatgtt ttcacacgtc cgactacgtc
    28981 atctgatttg tatgtcaaga tttcttgtaa agtataagcc gcaccgtaag cttccagtgc
    29041 ccatacttcc atttcaccaa aacgttgtcc accaaattga gctttacctc ccaatggttg
    29101 ttgtgtaacc aatgagtaag gtccgattga acgtgcatgc aatttgtcat cgaccatgtg
    29161 agcaagtttg atcatgtaca tcacaccgac agacacacgt ccatcaaatg gttcacctgt
    29221 acgtccgtcg tacagaacag ttttcgcatc gctggccata ccggcttcac gaactgtttc
    29281 ccatacgtct tcatcacttg caccatcaaa tactggcgtt gctacgtgga tacctaactg
    29341 acgtgcagcc atacccaagt gtaattccaa tacttgcccg atgttcatac gtgaaggcac
    29401 ccctaaagga ttcagcatga tatcgattgg tgttccatca ggtaggaatg gcatatcttc
    29461 ttccggcata atacgggata caaccccttt atttccgtga cgaccggcca ttttatcccc
    29521 ttcatggatt ttacgttttt gaacgatata aacacgaact aacatgttta cgcctggtga
    29581 caattcatct ccagcttcac gagtaaagat tttcacatcg tgaacgatac cgccgccgcc
    29641 atgtggtaca cgtaatgatg tatcgcggac ttcacgagct ttttcgccaa agatcgcatg
    29701 caatagacgt tcttctgcag ataattctgt tacccctttt ggcgtgactt tccctacaag
    29761 caaatcgcca tcttggactt ctgcaccaat acggatgata cccatttcgt ctaaatcttt
    29821 taatgcgtct tccccgacat tagggatttc gcgtgtgatt tcttcaggtc ctaattttgt
    29881 atcgcgggct tctgattcat attcttcaat atggatagaa gtgtatacgt catcttttac
    29941 caaacgacgg ctcatgatga tcgcatcttc atagttgtac ccttcccaag tcatgaaacc
    30001 aactaaaacg ttttggccta gagccatttc gccttgttcc atagatggtc cgtctgccag
    30061 agtatcccct ttttcgactt tctcacccaa atgaacgatt ggacgttggt tgtagcttgt
    30121 tccggagttt gaacgacgga attttgttac atcgtattta tctaatgcac cgttgtcgcg
    30181 gcgtacgcgg atttcagaag catcaacgta ttcaacgaca ccgtcatgtt tacataacaa
    30241 agcagctcct gagtcatgcg ctgatttgta ttccatacca gtaccaaccc atggtgcttg
    30301 aggattgatc aacggcactg cttgacgctg catgttggca cccatcaagg cacggttgga
    30361 gtcatcgttt tccaagaaag gaatacatgc tgtcgcaacg gcaactactt gtttaggtga
    30421 tacgtccatg tagtctactt tatcaataga tacttctaag ttttcacttt gagcacgagc
    30481 cataacaacg tcttgagcaa atgttccatc ttcattcaat gggctgtttg cttgggctac
    30541 gatgtaatgg tcttcgatat cagctgtcaa gtagtcgatt tggtcagtaa cacgacctgt
    30601 ttcacggtct acacgacgat aaggtgtttc gataaatccg aatttattta ctttcgcata
    30661 actggacaaa ctattgatca acccgatgtt tgggccttca ggagtttcga tcggacacat
    30721 acggccatag tgggagtagt gaacgtcacg aacttcataa ccggcgcggt cacgagtcaa
    30781 tccgccaggt cctaaggctg aaagacgacg tttgtgtgtc aattcgccaa gagggtttgt
    30841 ttgatccatg aactgtgaca actgagaaga accaaagaat tctttgatac ttgccacaac
    30901 tggacggata ttgatcaatt gttgaggtgt caatgtttca gtatcttgga tcgacattct
    30961 ttcacgaacc acacgttcca tacgtgctag cccgatacgg aattggtttt gtaaaagttc
    31021 accgactgaa cggatacgac gatttcctaa gtggtcgata tcatcgacat tgccgatacc
    31081 ttccatcaag ttcaagaaat agctcattga agcaatgatg tcggctggac gaaccgtttt
    31141 tacagctgct tctggatagc cgtttccgat cacgtttact tcacgttcag ggtctcttgg
    31201 tgaaaatact ttgatgactt ggacagtcat tggatctgtg accacaccgt cttctgatgg
    31261 atagtaagtc actgaattta ggccattatc aatgaaagga gctagtgttt ccatgacttg
    31321 gtgagtcaga actgttcctt tttcaacgat gatctcgcct gtttctggat caactaatgt
    31381 ttcagctaat gtcagattca atagacgtgt tttcaaatct aattttttgt ttactttgta
    31441 acgaccaacg tttgctaagt cgtaacgttt tggatcgaag aaacgagcat tcagcaagtt
    31501 acgtgagctg tctgctgttt ttggttcgcc tggacgcaaa cgttcgtaaa cgtctttcaa
    31561 accttcttct gttcttgagt cgcttgcgtt tttatgcaag tctttttcga ctgtattgcg
    31621 taatgtttcg ctgtcgccga agatttcaaa gatcgtatca tcggaaccaa atcctaacgc
    31681 acgaactaat acggttaaag gaatcttacg tgtacggtcg atacgtacat aagagatgtc
    31741 ttttgcatca gtttccattt ctagccaagc tccacggtta gggataacag tagaaccgaa
    31801 tccttctttt ccgtttttgt cgacttttcc atggaaatag acacctggtg aacggactaa
    31861 ctgagaaacg attactcgct ctgccccgtt gatgatgaat gttccttgtt ctgtcattaa
    31921 tgggaaatca ccgaagaata cttcttgtgc tttgatttcg ccagtctcgc ggtttgtcaa
    31981 acgcaatgtt acatgtaatg gtgcagagta gtttgcatca tgcgcacgag cttctgctac
    32041 tgtatacttt ggttctttca attcataatc tacaaattcc aaagatagat tgccattgaa
    32101 gtcatcgatt ggcaaaatgt cttcaaacat ttctctaagt ccctcatcta agaaccattg
    32161 gtaagagtct gtttgaattt cgatcaaatt tggtaattcc aacacttcac tgattcttgc
    32221 gaaacttcta cgttcgcgat gttttccgta ttttactacg tgtccagcca agctcttcac
    32281 ccctctaaaa tgtcattcaa aaagactacc cgatcaattg ttacaataat atttcaaata
    32341 ttatttttag gtaacaacag acattttttg cggcttttag gcaaaaaaaa accaaaaata
    32401 gaacattctc ttgaaacctt acttcgtgag cttctacttt tgtttcctta tattaaagcc
    32461 gaaacggaca atatttcgtt tctgcctttt cttcatcaga tagtttttgc aacttcatat
    32521 actacactta ttttctataa aagtcaacac ttcctggcgt ttcttctgct ttttcgcaac
    32581 attttcttaa tgttttcaat tttatgtttt caattatctg acaattctta attgacagac
    32641 ctttttatct cggttatact ttagaaaatt cattttgtgg aggaacttct atgcgaacca
    32701 acatcaacca aatcgcacca acacaactga ataactttta ctttagctac tttagatagg
    32761 tttgtattca tcatgatgga tacaaacgtt aaacgacagt ttgtatctat gatggctaaa
    32821 gaactttgta ttgcagcaaa aagccacgta gacaaaatgc taagtggctg agcagtgaaa
    32881 atacaaagta aaagtatcaa gcattctact ttttcaattt attttccgac ttttcaatcc
    32941 atttggacat tttgtctgaa tggatttttt gtttcccaaa attaaggagg aaaaagaaat
    33001 gaaaaaaaat ataatcatcg gattaggcgc tgccctgcta ctagctttag gaggttgcgc
    33061 acaaaaagac aattccgcag aggcatcaga tggacaaaaa acaattggcg tattgcaact
    33121 tgtacaacat aactcgttag atgctgccta taaaggattc aaagaaggat tagcagaaga
    33181 agggtataaa gaaggcgata atctaacaat cgattatcaa aatgcccaaa acaatcaaga
    33241 caacctgaaa agtatgagtg agaaactcgt caaagaagat cctgatttgc tacttggaat
    33301 cgccactcca gcagcacaat ctttattaaa tgaaacaacc actatcccga tgactgtcac
    33361 agcggtcaca gacttggaac aagcccattt agtcacatcc aatgaaaaac ctggcggcaa
    33421 tgtgactggc acgacagata tggtgccaat cgaaaaacaa atcggcttac tgttaaatat
    33481 cgtgccagac gccaaaacaa tcggcatcat gtataacaac ggtgaagcaa actctaagat
    33541 ccaagctgat ttggcagaaa aagaattgaa aaaagcgggc gtcaaagtca aagtactgac
    33601 agcaaattcc acaaatgatg tccaacaagt gacgaaaagt ctagctaaag atgtagatgg
    33661 aatctatatt cctactgata acacgttcgc aagtgcggca agtgttgtcg gtgaagtcgc
    33721 aaaagaaaca aaaacacctg tcgttgctgg cgcagttgat caagtcaaag acggcggtct
    33781 agcaacagta ggaatcgact acgaaagctt gggcaaacaa acagggatca tggcagcaaa
    33841 aatcttagac ggcaagaatc caagtgaact tcctgtcgaa acagcgaatg atttggaact
    33901 gtatgtcaat aaagacatgg ccaaagcatt aggcatcaat ccagacagca tcaaagaagc
    33961 tgaataaaac acaggaggat tctcatgaca aatttgctct ctcttttctt atcatctgca
    34021 tcgcaagggg tcttatgggc cctacttgcg attggtgtat acgtcacttt ccgtatcttg
    34081 gacattgccg acttgactgc tgaaggaagc tttcctttag gtgcagggat cgcggcagta
    34141 agtattacaa atggctatca tccattgaca gcttgtcttc taggcttttt agggggtgcg
    34201 gcagcagggc ttgtttccgg actgcttcac acaaaattga aaattcccgc ccttcttgca
    34261 gggatcatca ccatgactgg tttatattct gtcacatccc gtgtgatggg tgcgccgaac
    34321 atctctttat tgggtcagcc aacgatcttt cattgggtcg agtcattcgg cataacaaaa
    34381 gacaacgctg tactgatcgt cggtctgctt tttgctttga tcgttgtatg tttacttgtt
    34441 ttgttcttac gtacagaaac aggacttgct attcgtgcaa ctggcgataa tctggcaatg
    34501 agcgaagcaa acgggatcaa cacagataat atgaagatca tcggttatat gatttctaat
    34561 ggatgcattg ctctttctgg ctccttactt gcgcaaaaca acggctttgc tgatttaaat
    34621 tctggtattg gaacgatcgt aattggactt gcttctatta tcatcgcaga agttttgtta
    34681 cgtaaccagc cactatttct ccgtctcttg actgtcgttt taggtgcggt catttatcgt
    34741 tttattttag cgttagtctt cgaactgaat gttgaaccaa gtgattcgaa acttgcttct
    34801 gctttcgtgc tagtgatctg tctttctttc ccgcagatcc agcaaaaatt ccatttacct
    34861 caaaaaaaga aaggcggtag tgtcaaatga atgacgtctt aacattggaa aatctccatc
    34921 atacctttga aaaaggaacg atcaacgaaa atcatgtcct gaaaggcatt aatctttcct
    34981 tagatcccgg cgacttcgtg acgatcatcg gtggaaatgg ggctggtaaa tctactttgc
    35041 tgaacagcat cgccggtaca ttttctgtcg atcagggtca aattttattg aatggaaaaa
    35101 atatcacgaa aaaatctgtt gtcgaacgtt cgaaatccat cagtcgcgta ttccaagatc
    35161 ctaaactagg gacagccgtt cgtttaacgg tagaagaaaa tcttgctctt gctatgaaac
    35221 gaggaaaaaa acgcggcttc ttccgtggtg tcaaaccaca agaccgaaca tttttcaaag
    35281 accagctggt tcggctaaat ttggggttgg aaaatcgttt atcctcagaa atcggtttgc
    35341 tgtctggagg acaacgtcaa gctattacgt tattgatggc cacattacag cgtccagaac
    35401 tgatcttatt agatgaacac actgcagcgc ttgaccctgc tacttccaaa acggtgatgg
    35461 aattgacaga aaagctgatc actgagcaga atctcactgc ttttatggtc actcatgaca
    35521 tggaagacgc gatccgctat gggagtcgac tgatcatgct gcatcaagga aggatcgtcg
    35581 tagatatcca gcaagaggaa aaacagcagc tcacagtgcc ccaattatta gcgttgttca
    35641 aacaaaacag cggcacggca ttaaaagacg atcaagtact tttatcttca taatcagaaa
    35701 gaggatggga caaaaaatga acgcccaccc tcttcttttt tctctttcct tctttcgttt
    35761 ttgctttatg tatcaaccgt tgtttcttcg aaaactattt tgttctctcc ttcttcctga
    35821 tagaatggat gggaaaggag cttgatgcca tgacaacgaa agacaaggta cttcaattat
    35881 tgaaaaagac accagatttt ctttccggag aaaagttggc acagcaactg gaagtttccc
    35941 ggacaagtat ttggaaagcc atcaaagaat tggaaaaggc aggctatcgt tttgagcacg
    36001 ggcctacagg gtatcgttac ctgccctctg acgtactaga tgcaaaagaa atccagcaag
    36061 agctacggtc gtttattcct gatttgaaag tacaaacgat gttgacttct gaatctacga
    36121 tgaaagatgc caaactggca gcagctcaag gagattctgt ttcgaagtta tttgttgctg
    36181 atacacaaga acaagctcgt ggacgttttg gacggccttt tttcgctgaa cctggacgag
    36241 gaatctacat gagtctcttg ctccatccag acaaacggtt tgatgaattg cctcaatata
    36301 cgatcatcgc agccagtgcc tgtgtgaaag ccattgaatc tgtaaccggt cgttctgctt
    36361 cgatcaaatg ggtcaatgat atctacatgg atggaaaaaa agtctgtggg attttatctg
    36421 aagcagtcag tgatatggaa agcggcagga tcagtcatat catcattggg atcgggctta
    36481 atttttctgt tcctcaaaat cattttccag ctgatctcca agaaaaagcc atctctgtct
    36541 ttcccgacgg acaagctagt gtcacaagga atcagctaat cagcaaaatc tggcaagaat
    36601 tgttcactta tctttctcac ccagaaaaag cgttggactt ctataaagaa aaatcattcg
    36661 tattgggaaa aaccgtgtcg ttcaatcaaa aaggaacgac ttatgtcggt cttgcaaaag
    36721 aaatcggtga tcatggcgaa ctgatcgtcc aaacaaatga acagaagatg agtttgtctt
    36781 ctggcgaaat cagtctcaca tctatccgta cgcaataatt atcagatttc acaaaaggac
    36841 acctgatctc atacagtgtc cttttttctg aattctcttc aaaagactct ccttattcta
    36901 tcagctgaca gtttctctat cctctagaaa aaggtattct aaaaatatct ataaagcatg
    36961 gtacactttc tttaaatgaa tcaatgcaaa aaacaagaga gtcatcagtt tacacgatca
    37021 aaagagatag caggccgctt cctttttcaa tcttatagat agaccatggg taacgataaa
    37081 aacaaaaaag aacttgcgac ttattttgcc gtaagttctt ttttagctag tgccttaatc
    37141 tcttaatccc aacaaacgtc tcgcatagat cacctgacca gagtgcatag cagcatcatc
    37201 aataatagaa acgagacgca ttcctcgtgt gactggtggt gtccagttct cgtcaattac
    37261 ttcatctagc tcggaaggtt ccagccttct taagtaagaa atagcaaaat cagcagctcc
    37321 tcgcaagtat cctagcagat cttctatttg attagcttgg atctgctttg cttgttccag
    37381 actatgcttc caatcttgtt cgttatctgc tatcgtcatc ggaaaccggc tttcccagtc
    37441 ttgactatgc caaattggag aagttcctgc taaatcagca atctggaaat ctaattctcg
    37501 agcggtatgc caagccagcc aagtcattga tttgatctgc ggggctctat cttccactgg
    37561 aaaacgattg gcctcctcaa tagagacgcc ttcaaacaaa cgttcaaacc gatcgtatgc
    37621 ccgatccaca ctctcgcata gcatatctaa ataatccatt tattttcctc ctttttattt
    37681 atcctactta ctttttccta attctaggat acctacttat atgttactac acacccttat
    37741 tttttacact ttaacagtca ccatcatcaa tagtttggag attgaaagaa aaagatagtg
    37801 tcgaactatc aattgaacaa gaagcaacaa tatgaacgtt tcattaatat tctttaaata
    37861 aacaatgatt tttcaaacga acagtttaag actaggagaa aaagagtata ataggaaaat
    37921 gtttgaaagg aaaggaaggg gaaaaatgaa aaaaagggca agtttactag tcctagttgc
    37981 tttgttgttc aatatctttt cgtatggtgt ggccgtttca gcggaaacat acattcctaa
    38041 agaccctggg aatatttata atgatctaac tggtaactat ggcttgttag gaattgctag
    38101 tcaattccac gtatttgcta aaaataagac aactgtgaat gcacatacag acggaaatat
    38161 agcaacacat gaacttgatg caaaaaataa ttttggtaca gagcttcatg aaggtttatt
    38221 gaaccaagaa ataaattata tacaaaaaac tgattctttc gctaattctt caggcatacc
    38281 tacaggtagc acaagaatga ataaatttgt cgttggcagt aacgtggatg tagcacttca
    38341 agatggtcat cctacagtca atggatccag gcttgatcac ttaactccag atgattttta
    38401 taaagatcgt gctgggcatg aatatattga tttcgagcag gaatttgcta aattgaatgt
    38461 agcagcaaat gatcttgcaa cgatcactcc agctaaaaca tatactgctg cagattttcc
    38521 agacatgaac aatcggacaa tcgatttaac tgatttatca gataccgggt ttttattggt
    38581 aaatatcgat gcagaagtgt taacgatgaa tacgccactt caaatcatta atccaaatga
    38641 tcaagtagtt gtatttaatg tcatcaacag ttcttctgca ttgaacgtac agtcaccaat
    38701 caaatacaat gatcgttcaa atcatgaaac agaagatttt tcggatgcga atatctcttg
    38761 gaattttgga aatgagatga ctgatttgac aatcagtgct ccttttcaag gaacaatcct
    38821 tgcgcctaat gctactatcc gcattactca aaaccaagac ggaacgatta taggaacaaa
    38881 tgtgatttta gatgcagcta ccaatcgttg ggatcctaac gaaatattta tcagcgacaa
    38941 tggtacagat acgacagaca caagcgacag tacagataca tctaccacaa gtgatagctc
    39001 agattcatca
//
LOCUS       DAFTHM010000016        37505 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFTHM010000016 DAFTHM010000000
VERSION     DAFTHM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.016"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            36..917
                     /locus_tag="L7C88_000835"
     CDS             36..917
                     /locus_tag="L7C88_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557686.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTVVEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            930..2540
                     /locus_tag="L7C88_000836"
     CDS             930..2540
                     /locus_tag="L7C88_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBP9557687.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRMGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2617..3276)
                     /locus_tag="L7C88_000837"
     CDS             complement(2617..3276)
                     /locus_tag="L7C88_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBP9557688.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3559..4224)
                     /locus_tag="L7C88_000838"
     CDS             complement(3559..4224)
                     /locus_tag="L7C88_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBP9557689.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4371..4976)
                     /gene="dhaL"
                     /locus_tag="L7C88_000839"
     CDS             complement(4371..4976)
                     /gene="dhaL"
                     /locus_tag="L7C88_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBP9557690.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(5004..6014)
                     /gene="dhaK"
                     /locus_tag="L7C88_000840"
     CDS             complement(5004..6014)
                     /gene="dhaK"
                     /locus_tag="L7C88_000840"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBP9557691.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(5989..6435)
                     /gene="dhaM"
                     /locus_tag="L7C88_000841"
     CDS             complement(5989..6435)
                     /gene="dhaM"
                     /locus_tag="L7C88_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBP9557692.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            6538..6858
                     /locus_tag="L7C88_000842"
     CDS             6538..6858
                     /locus_tag="L7C88_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBP9557693.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(6970..7839)
                     /locus_tag="L7C88_000843"
     CDS             complement(6970..7839)
                     /locus_tag="L7C88_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBP9557694.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(7935..9238)
                     /locus_tag="L7C88_000844"
                     /pseudo
     CDS             complement(7935..9238)
                     /locus_tag="L7C88_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(9235..9744)
                     /locus_tag="L7C88_000845"
     CDS             complement(9235..9744)
                     /locus_tag="L7C88_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557695.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(9919..12054)
                     /locus_tag="L7C88_000846"
     CDS             complement(9919..12054)
                     /locus_tag="L7C88_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9557696.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(12137..13792)
                     /locus_tag="L7C88_000847"
     CDS             complement(12137..13792)
                     /locus_tag="L7C88_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBP9557697.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(13794..14108)
                     /locus_tag="L7C88_000848"
     CDS             complement(13794..14108)
                     /locus_tag="L7C88_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBP9557698.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            14278..14538
                     /locus_tag="L7C88_000849"
     CDS             14278..14538
                     /locus_tag="L7C88_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBP9557699.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            14552..14866
                     /locus_tag="L7C88_000850"
     CDS             14552..14866
                     /locus_tag="L7C88_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBP9557700.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(15596..16150)
                     /locus_tag="L7C88_000851"
     CDS             complement(15596..16150)
                     /locus_tag="L7C88_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBP9557701.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(16276..18204)
                     /locus_tag="L7C88_000852"
     CDS             complement(16276..18204)
                     /locus_tag="L7C88_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBP9557702.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(18510..19226)
                     /locus_tag="L7C88_000853"
     CDS             complement(18510..19226)
                     /locus_tag="L7C88_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBP9557703.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(19227..21050)
                     /gene="glpO"
                     /locus_tag="L7C88_000854"
     CDS             complement(19227..21050)
                     /gene="glpO"
                     /locus_tag="L7C88_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBP9557704.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(21064..22560)
                     /gene="glpK"
                     /locus_tag="L7C88_000855"
     CDS             complement(21064..22560)
                     /gene="glpK"
                     /locus_tag="L7C88_000855"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBP9557705.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(22696..24156)
                     /locus_tag="L7C88_000856"
     CDS             complement(22696..24156)
                     /locus_tag="L7C88_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557706.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(24146..25441)
                     /locus_tag="L7C88_000857"
     CDS             complement(24146..25441)
                     /locus_tag="L7C88_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBP9557707.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(25773..26450)
                     /locus_tag="L7C88_000858"
     CDS             complement(25773..26450)
                     /locus_tag="L7C88_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBP9557708.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(26480..27571)
                     /locus_tag="L7C88_000859"
     CDS             complement(26480..27571)
                     /locus_tag="L7C88_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBP9557709.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(27672..28106)
                     /locus_tag="L7C88_000860"
     CDS             complement(27672..28106)
                     /locus_tag="L7C88_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBP9557710.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(28690..30147)
                     /gene="ascB"
                     /locus_tag="L7C88_000861"
     CDS             complement(28690..30147)
                     /gene="ascB"
                     /locus_tag="L7C88_000861"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBP9557711.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(30144..32039)
                     /locus_tag="L7C88_000862"
     CDS             complement(30144..32039)
                     /locus_tag="L7C88_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBP9557712.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(32097..33872)
                     /locus_tag="L7C88_000863"
     CDS             complement(32097..33872)
                     /locus_tag="L7C88_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBP9557713.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(33922..35418)
                     /locus_tag="L7C88_000864"
     CDS             complement(33922..35418)
                     /locus_tag="L7C88_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBP9557714.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(35612..37234)
                     /locus_tag="L7C88_000865"
     CDS             complement(35612..37234)
                     /locus_tag="L7C88_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBP9557715.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
BASE COUNT        10486 a         8003 c         6466 g        12550 t
ORIGIN      
        1 tagtatatat ttttagaaaa aggagtgggg tttttatggc agaaatcgtc aaagtcacac
       61 atttgaaaaa gagctttggt cgtttcgaag ctttaaaaga tgtctctttc accgtacatt
      121 caggtgaagt cgttggattt atcggaccaa atggttctgg aaaatccacg acgattcgga
      181 cacttttagg gattataaaa aaagacggcg gaacggcaac gatttttggg caagatgtat
      241 gggaagatag tttatctatc catgaacgtc tttcttatgt tccaggcgat atctctttgt
      301 ggggaaattt gactggagga gcgatcatcg atctcttcat gaagcttcat ggaaaaggga
      361 gtgctcaaaa aaaagatgaa ctgattcaac gtttctctct tgatcctaag aaaaaagcaa
      421 aaaactattc aaaaggaaat cgccaaaaag tgggcttgat tgctgctttg gctgttgatt
      481 cggatctcta tttatttgat gagcctactt ctggtttaga tcctttgatg gaaacgattt
      541 tccaagaaga agttgaaaaa ttgaaagaac agggcaaatc catcctactt tcttctcata
      601 ttctcagtga agtcgagcga ctagcggata aagtcgtgat catacgcgaa ggaacagtcg
      661 tagaagaagg aacactcgat gaattgcgtc atttgactcg ttcgaccatc actatagaaa
      721 cagaagcaga gaatagtcac ttagcacaat tgaacggtgt ccatgacttt gtgcaaaaag
      781 gtcacctcgc tcaatttgct gctgataacg aagctttcga tgtgatttta gctgaagcgt
      841 ccaaattagg tgtgaaaaaa tttgaatcta ttccaccgac tcttgaggat ttattcatga
      901 gacattatga aggatgagga ggaagcgaaa tgactgataa attttcacgc tggtccaccc
      961 ttttttctca aaaccttagc cgtgactgga aaaagatcct gatatggcta gtcggtgtca
     1021 ctgctttttc tggtggtttt gtccctgcgt ttgaagaatt gacttccgga caaggattag
     1081 ctggattata cgaaaccttg caaaacccgg caatgattgc aatggtcgga ccaactccag
     1141 cttcgaatgc tgctgagtat actttaggag cgatgtatgc aaatgaaatg ttgctttttt
     1201 gcagtttgtt tgctgctgtg atctctgttt tacacgtggt gagccaaacg agaaaaaaag
     1261 aagaacttgg tctgattgaa cttattcgtt cctttcgagt cggacgtcaa gcaaactctt
     1321 tagctgtcat cgctgaaagt attctgatca atttgctttt agcaatatcg atcagctgta
     1381 cgatgatttt tttccaagca gattcgatca ctgcagaagg tgcttggctt tttgggctat
     1441 ctgtaggtag tatggggatt ttggggagtg ccgttgcact gtttgctgca caactgatgc
     1501 caagttcagc cagttcgaat ggtctgtctt tagcgttttt aggtggactt taccttctac
     1561 gagcaataac agatgtagct gattcctccc tttcgatgtg gaatccttta ggctggtctt
     1621 atttgaccta tccatttaca actaacaact ggattccttt gctttatttg tttttgttca
     1681 gtctaatctt gataatcagt tcatttgttt tagaggaaca tcgagatttg aacaccggct
     1741 atatccccga acgtgaagga aaaccgtatg ctaaacgttc tcttttatcc ttgcgtggtt
     1801 tattattcta tctaaataaa gggatgacaa tcagttggct tatcactttt ggtttgatgg
     1861 gggcggcata cggctctatc tacgggaata tgcaacagtt tttagaaagt aacgacttaa
     1921 tgaaacagat gtttatccaa tctggcgtct caattgaaaa aaactttaca agcacgatca
     1981 tggtcgtctt gatttgtcta gctgctattt taccaattgc tagcatcaat cgtttattta
     2041 cagaagaaac ccacggacgt atgaatcagc tgttcgcaac aaaaatttct aggaaccaac
     2101 tttattggac caatatgtta ctagctattc tatttgctat attggcaatc ctgattagtt
     2161 ctggtgcact agggctttct gctttggctt cgatgaagga tgcgaaagac atggatctat
     2221 tgatgtttct taaagccggg ttcaatttcc tgcctgccgt tttagtgttt atcggaatta
     2281 gtggctttct attcggatgg cttcctcgaa tgggtaaact tgcttatatc tacttagctt
     2341 actcctttgc actcaattac tttggcggaa ttttggattt accagaatgg ttttccaaaa
     2401 cagctgtccc tagctgggtt ccacggatgc caaacgattc ttttgatctt tccgtgttcc
     2461 ttacgttatc atgtatcagc cttgcactgt tcgtccttgg ttctattggt tataggcgaa
     2521 gagacttact agaaggataa taaaaaagca tgtacaattt catgctagcc tccaaatctg
     2581 ggtcaaaaat ccaacatttg gaggtcattt ttttatttac aagtcttcta actgctcttt
     2641 atcaatgatc cagacttctc gattctttct ttttacataa ccattctcct ctaataattt
     2701 aaattttcta gataaagttt cgggggtcgt accgataaat gcagcaagtt ctttcatttt
     2761 cattggcagg aaaaagtgat ccttccctgt cgctttagct aagtcaagca gatagacagc
     2821 gactcgttct tctacttttt ccatcatcaa aaaagttgtc tgctgctgta cttttgttaa
     2881 tttctcaacg ttgattgcta aaagtttcag actaagggcg ggataatgca gtaagagttc
     2941 cgagaaatct ttttgtctca atatgcaaat ttccgttttt tctagtgctt cgccaaataa
     3001 agactcattt ggaacgccta gcaactggct ctctccctca tatccgcccg gctctattac
     3061 tcgtaaaagc tgttcctttc cgctagcaga taattgatac actttcatac tgccggaggc
     3121 cacgatcact aattgaggtt ctccattcgg cgcaagaatc tgttctcctt tttccacata
     3181 gtgatgtttg acaagtgcgt gtactttttc ttgatcttgc tgtactaagt gattgaacaa
     3241 aggaacaaat gaaacacata aatgatcatg actcataatc tctcctcctt ctaaacagct
     3301 atttctaata aagaaacata acttccctta ttccaactga taattttctt ttatcatagc
     3361 ataaacgtca agcgaaccag ataccagcaa atagagtgga tttctttttg tcccttgctt
     3421 tattttcctt cttttgagac cttaagtaat tgattcctat caatttttta aatatttact
     3481 ttttgaataa tcaaaaacaa accttcactc gcaagccgag agtaaggttt gtttttcgca
     3541 ttgcttattt cgtgttgtct attgaaattt ttccgcacct agcttttgat atagtggtgc
     3601 tagttcttgt aaggtttcag cggttatttg ctcaacgtgt tcgatttctt gcggatagaa
     3661 gaatagttta cccatttgaa aggttcggtc tctcatcgct tttttcaact cttcttgttt
     3721 ctttgtatcg gacaaatagt cagacaaagc taagtggtcg tcaagttcat gttctggttg
     3781 cggccatatg taataatcct tgatatcgac tgttttgctc cactctttca gtatcgcaag
     3841 caactggtta tacgctgcaa tgctaccata tcgttcttcg cttttataat gttggtacat
     3901 caaatagatt tggtattgtt tttgattcaa caaaactgct agacaggcat tctcgtcttg
     3961 acgagattcg cttcggtacg cgctccaaaa atgactgcgt aaattccagc cattcgtcca
     4021 gctttcgatt ttaggtttgc tcatgccgta catatcaggc aaaagtgcag ctgtctggag
     4081 ctgaatctct ttccattttt gccagtgttc tttatattct ttcttgattt gttcaatctt
     4141 atctgttgga tggctctctt tgagctgttt gaatgcgtag attggtcgat caaacaactg
     4201 ataatctgat tttccaagtt ccattgtttc gcctctttcc gttatctttt gtattctacc
     4261 tgaattttgc gatatggaca aatagaggtt gtgaaaaagc tgttctgcat caagtcataa
     4321 gaacagccaa acaaaaaact gcgatgagca tcaccgcagt tttattgaac ttaaggttga
     4381 ttgatcacat ctaaaagcgt tgaaaataaa atggcactag aagcagctcc tgggtcgata
     4441 tgtccgattg cacgctctcc tagataggaa gctcgtcctt ttttagctac caagactttg
     4501 gtgtgttctt ttgcctggtc aatgatttct tttgttaaat tccctgcctt caatgcctct
     4561 gtgactggca gccaaacatc taacatcgtt ttatcgtcag cttctgcctt tcctcggctt
     4621 tgaatacccg ctgttccctg ctcgatcact tcgcctaatt tttcttgaga atcaatagaa
     4681 tcgacctctt ttgtcgcttt catcatgttc atgaatgcag atccgtataa cggaccagaa
     4741 gccccaccga ctttcgatat catcgccata gagaatactt tgaatgtatc gctgattgtt
     4801 tcaggatgat cggcttgaaa agcttcttca taagctgaaa cccctcttcc catgttattt
     4861 ccatggtctc catcgccaat cggggtatct agatcactga gatattgttt gttctgattg
     4921 attgcctctg caaattgcgt gagccattct tggatttctt gaacggttag tttcatatta
     4981 tcaccctttt atcttgagat tttttaccat gaaatcgtct gtacattgct ttctaaagaa
     5041 tctttccatt gtgtctccgt caagtcgatc agtgttagag aaagaccttg catatctagt
     5101 gaggtcataa aattaccgac ttttcggaaa actacattga cgcctctttc ttccaacaga
     5161 gctaaaacat cattcatgaa cacgaactgt tccatcaaag gcgtcccgcc cattccgttg
     5221 actagtacac ctgcttcttt tggtaaattc gagtaatcat ctaaaatctt agtaacaagt
     5281 tcctttgcca gtactttaga aggctgcatc ttttctcgac gatagcctgg ctcaccgtgg
     5341 ataccaacac catactcgat ctcatcttct cctagttcga atcctggttt ccctacttct
     5401 ggtacagttg ctgctcgaag cgctagaccg atcgtcttag ttgcctgtac gaccttttct
     5461 cccagttctt tcaactcagc tagggaagca ccgtttcttg ctgcatcgcc cacgattttg
     5521 tgtacaagga cagtacctgc aactccgcgt tttccagcag tatacgtact attttcaacg
     5581 gcgatatcat catctacgat cacactttct acttcaatat cgtccatagc agctaattcc
     5641 tttgccatat cgaagttcaa tgcatcccct gtataattct taacgatcag caaaactcct
     5701 tttccactat ccgcttcctt aatagccgtc tgaatctgat ctggagttgg agaagtaaac
     5761 acatcaccaa gcaccgctgc acttaacatc ccttccccta caaacccggc atgggatggt
     5821 tcatgtccgc ttcctccacc agaaaccaaa ccaacttgtt ccgctttctg attcttggct
     5881 acaacacggg aagattctac acgatgaaca agttctggat agctttttac taatccttcc
     5941 agcatttctt cgacaatatt gcttggatca ttcatgattt ttttcaattt attcccatcc
     6001 tttctttccg gcattttgtg cttctgttaa gatttgctga gtatcatctg ttataccggc
     6061 agtgatggct gctgcaaaag ctccttccac taaaggcgca tccaccagat gataacgttg
     6121 ctgctgctct tcttccaaca tgtcttttgc cagttccgag ttcaataccg cgctaccgat
     6181 atccgcaaaa acaaaataac tagctgcatc gcttgattca ttgactgctt ctacgatttt
     6241 catcgggtct gatccgatct cgccatttat tccgccgaga gaaaaaattt gcacctcttc
     6301 ggatttttgc atctgctcaa tcatttcttt aataccatct gttacttttt gactatgaga
     6361 aataagcaaa atactttttt tcacaagaat cttcctttct tttacatagt tgctaacgat
     6421 tggtttcgct ttcattaatg aacaattcaa gtatataata aatttctaat tttgggaaga
     6481 tatgtgtagt gcttcttgaa gtttgttata ctttaattaa aagagaggag tgatcgaatg
     6541 attacaacaa caacgaacag tgtagaggga aaagccgtag tagcttataa agggatcgtt
     6601 tttggtgagg tcattactgg gatccatgca tttaaagact tggaggcggg gttgcgaaat
     6661 atctttggcg gccgctcaaa aagctatgaa aacgaactaa tgggtgcaag agaagaagca
     6721 cttgccgaaa tggccgaacg tgcaaaagca ttaggagctg atgcgatcat tggcgtaaaa
     6781 atggactatg aagtattagg cagcgacaat ggcatgctga tggtcacatg tagtggaaca
     6841 gctgtctcca cgagataagt aggggacatc tgttttaata actaaagaga gatgggacat
     6901 gtagtggcac tcaagaatta gatttttcag tctaacttcg aggtactcta ccttcccatc
     6961 ctctcttttt tatttctttt tgcggatgat tccgtaagct gctgcgacta acacacccgc
     7021 ccctgctaag gaataactga cagaagctgt tttttcattt gtttttggca aagtctgact
     7081 tgttgatttg gatggctctg tcgtttgctg aactgtttct gtcgtgcttc cagaggtcac
     7141 tgatttttct cctgccgaat gcaaaatatc ttttattcgt tggaaactag ctgctaagtc
     7201 agcttttttt gcttcaaaat cattagcaac tgtttgtgct tcgctgatct ttccgtggat
     7261 tgcttgactg gccgctgtga tatccgcttg agtttgactt agctttccag aagctgtttg
     7321 agcaacctga tttaattgct gattgaattc ttttgcttgt tggatcttcc cgtcaagatc
     7381 tgtttggaca gcttccgctt ttgctttcgc ttcggcaagc tttttctcaa gttgtgcacg
     7441 gtcatttccc actttatttt taagatcagc taaatcttga tcgattgctg cttggtcttc
     7501 tttcaatttg ttttttgcag cttctaatgc ttcttcgagt tcttttcttt tattttccaa
     7561 gtcttgcaaa tgatcgattt ggtcagaaga ggtagaacta tttattgatg tatcttctga
     7621 agatgaaatc gtttctcctg aattatctgt cggtacattg gaagtcattt ctgtttccga
     7681 ggcaccgttt tcagcaccag aagagcttat agttgttgaa ggttctgttt gagcaggttc
     7741 agaagtttcc gcaaaagctg tctgtcccaa taagaaaata ctggaaacag caattggcca
     7801 gattaacggc ttcattcttt ttttcatcac ttttcccatc cttactactt tttaactaat
     7861 ttcttattat aagcaaaaat gtttggaaga accataaaca caacaggctg tttgtctaaa
     7921 aaacggtgca tcttttattt ttttgtacgt tccgggcttt tccatgtccc gcttccataa
     7981 cctaaaatcg ttttgactgc tggaatgaaa gtcgtcacga tcgttatcgc gttcactatc
     8041 cagaacaaaa gcatatatag tggtgcgaaa agaaggtatt tcaattttct tcgtcgatca
     8101 tctacaatca gcgaagctag caactggaaa aatcctgcga ccatttcaaa gcagatgaac
     8161 acaaaactga atgtaaaagt aatataaatc tgttcgtagt ttccttgata tacataatgc
     8221 ccgattaatc cagcaaaaag aactacggaa atacaaaaga atattgacca gacaatactc
     8281 aatgtttgat caatgaagat gatcgttctt ccaatatgtt taaaaggatg gagcatcact
     8341 tttttgaaat tcgtcagcca gacttctgtt ccaccttttg cccaacgttt tctttgtcga
     8401 tatagcatct tcaacgtcac aggtacttcc atgaaaaaga taatctcagg agcaaaaaca
     8461 gataaccagt catttaactg atgatcccaa gcaatactga tgtcttctgt cgctcgatct
     8521 tgtctgaatc cgcccacatc gatcaaggct tcttttcgat acatcgtatt tgctccactg
     8581 tacgcataaa gaccaccgaa aacagctgac tgtgttcgtt taatgatgcc cacgatactt
     8641 gagaattcaa ccgtttgaga ttttgcaatc aatttggtac gattttggac atccatattt
     8701 gcagtgaccg cagcaatatg tcttgcacca gggcgaatga aataattcac atacctaatc
     8761 agtgcatctg gctccggtac cgtgtctgca tcattgctta aaatcaattt cccttttgca
     8821 aaggcaagtc cgatattaaa cgcgtgggct tttcctttat ttttttcgat ccgaaccaca
     8881 cgaagattag cgtatttttt catcagtcta gctaatattt ctggtgtttg gtccgttgaa
     8941 ccatcgtctg tcactaatac ctcatagttg tgataattca atttcgtcat caaatactcg
     9001 attgtatctt cgatcacaat ttcttcatta tgggctggca ccatgatcgt gatgaacggt
     9061 tcgacactca agggaacatc tacccattct ttttgcttat gtttgtataa aaacacataa
     9121 caccagacac caataaacca tacaaatccg cctaaaatcg gataagaaac gagaaaaaat
     9181 acataataga caaacaagta tctaagaata aattacctgt atgggtgatt gagatcattt
     9241 cagttccacc ccattttctt tatacaaatc tgcaatgaat gtcgtatcta gatttttctc
     9301 ttcggagaca gaataaaaac ggaccgtttc tctctcttct tttgttccaa aacgttccgt
     9361 atacacttct tcaagtaatt cttgtctttt tttcaatttt tcatcttcat attcaaaaga
     9421 tttatttact tttttgtata gatttcgatt gttccaccta gtcaatacaa atgaggtaat
     9481 caggaaactg aaaaaaatca atacaaaaaa gccgattaag aaatacagca ttttcttttc
     9541 tgataaaaaa gcgtacaagg aaaaatcctt ggctctttct ggtctcgtta atgggaaaaa
     9601 gacccatata aaaggaagaa caacgatcat ccatcctaaa agagccacta acgtttgcca
     9661 aatctttaac cagtaattac cttttgaaaa atacttatct ttcaccaaaa ttgatgcaac
     9721 ttcttctctt gttacttttt tcatatcctc acctcacgtt tttttgttac gacgtaggag
     9781 tttaccatac atttcatttc ttttcacata aagtgttcct aaatttttcc taagaaaaag
     9841 aacaaaacat ttctcatcag caaatgaaaa atattttgtt ctttttatca gttgttcttt
     9901 ttatttttta tctcttaatt atgttgctct ttccaatacg acaatgcttt tcattcctct
     9961 agatatcgcc gtgtacattt gtctgcgtct tctttgctca tctccatcgt tttcaaatgg
    10021 atataagatt acatgatcaa attccagtcc ttttgctaga ctcaaaggaa tgatttggca
    10081 gttttctaat ccatatgaat tttttttaat cgattcttgt agcgtttggg tttcctcttc
    10141 tgtttgggtg ataactgccg ctttttctcc ttttagagaa accaaaatct cagctagtat
    10201 tttcaacaat tcttcagagg atcgaaaaga gcggtattcg ggttcttttc cttgcggtcg
    10261 gatcgatacg atgtcgatct tctcttgatc cacagcatag gttttgaaaa gctctgtgat
    10321 tgctccgcta gaacggtaac tatttctaag atcataccga tggatcggca gatggtagtc
    10381 gtcgaaacaa cgcataatat cagcaaaagt agtggaagaa ttaaagattg cctgattctc
    10441 gtcacctact aaagtaaagt gagtttttgg aaataattcg atcaatagac ctaattgtgc
    10501 cagggtataa tcttgtactt catcaatcaa tagatagcga aatgctggta catttacctt
    10561 ttcaacaagt aaatgacgaa tagctaatat aatgactgct tcatcaacag tacgtgtggg
    10621 ttgccaagca taagctgagc catatcgttt ttcataaatt ctttcaaaca actgatgctc
    10681 atccacccat gccatttctt cgatttgtct ggttattttt cgatattttt tttgtaaaag
    10741 tttccttgca taagctacaa tactttgttc cgaatcatca gaaatcaatt taccgaataa
    10801 ttccaactgc ctatcttctg tcaacgagag tacctgattc tgcacagcag gactttttgc
    10861 ttgtttcaaa agatgattct tccattcgct catcagtgcc tttttcgttg cttgaagcct
    10921 atcgatcaat ttaggatgag caggaacttt ctcatatatt ttttcgatcg tttttttaga
    10981 aaggactgtt tttccatttt tagtaagtcc acggataaaa ttcggatgat ctaaaaacaa
    11041 aggatctgat tgttttagat tatcgataaa ctttttgcta cgcaaacgtt ctgtctgctc
    11101 cgatacattt tctcccgtga tacgtttgaa ataagcctct tcaccttcta tttcctctgc
    11161 tgaaagctgt gaaaccagct gtatgatggt tagattcagt ggatttcttt cacctaatga
    11221 tggtaggaca ttcgaaatat agtcgataaa ccgatgatta ggtgatagaa tcagcaagtc
    11281 atcggatgtc atcgtatctc gatataaata gagcagatac gcaatacgct gcatgatagc
    11341 agaggtttta ccacttcctg ctacgccatt taccaagata ttttgacttt tcacatcccg
    11401 aatgattgtg ttttgttccg attggatcgt agcagtgata gccttcattt cattggtctc
    11461 atcttggcct aagacttcta ataatacgtc atcttgaata gctacagacg tatcaaaaaa
    11521 cttgaccaaa cgatctcttt ccaaaagaaa ttgtcgtctt tctttaataa ccgtatcgat
    11581 tttattttga cgaaccgtat aagaagatgg accaatcatg ttattgtaaa aaagttcggc
    11641 aattggtgaa cgccaatcat aaacaagatt ttcatctgca tcatctgtga aatttgctgt
    11701 accgatataa aaggattctt ttggctcatt atccagaaag tctacaacga cttttccaaa
    11761 gtagggactt ttcaataaac gttcgatctt tgctagctga ttttctgcgt ttttctgttt
    11821 gatattcatc tgatcgattt ctctattttt catttcaatc atcgaaaaag tatccaggtt
    11881 atctaagtaa ctgtcaaaat tcaatcgaag ctcgccagcc atttctttca acgactggtt
    11941 tccttctatt tttgccgtat ccatcgattc ccgcagttcg ttttttttat caattagctt
    12001 ttgatacacg ttcttcagat atgcttcttc taactgtttt tgtgtgttga ccatacacat
    12061 tctcctcttt ttttaaagtg gtggaaccga ttagtttacc tcttttaaga gtcgaatgca
    12121 agctttttaa cgagtatcat ttgttaggat atatcagttc ttcaggtcgg acagtttgat
    12181 ataaagaaaa tgcaccatca aggtttttta cgtggtagcc agactgcttc aagattcttt
    12241 ccgctagata gctacgtaat ccgctatgac agctgacgat atattcttgt tggctgtcta
    12301 attcatttaa tcggtcccga agttcattca aagggatatg tttggcttcc ttgaatttgc
    12361 ccttttccaa ttcttctgct gttcgcacat ctaataaaat ttttcctttt gctagttctg
    12421 tcggcaattc atgccattgt acggtttcac taagcccttc tgcaatgttc attgctgcat
    12481 atcctagcat gtttactgga tctttggctg agccaaatgg cggtgcatac gtcaattcta
    12541 attccggtaa atcgaagatc gtcaaatgcc ctttgattgc tgttgctaaa atatcgatcc
    12601 gtttatccac accttttgcc ccaacacctt gtgcaccata aatctcgcca gtctctggat
    12661 ggaagatcaa cttcagtaaa atatctgttg cttctggata atagcttgca tgatcttttc
    12721 ctgatacatg aatgacttca aaagacagtt cgttttcttt ggctgttctt tcacttaaac
    12781 cggtggatgc ggcagtcatt ccaaacgttc gtataattgc tgttccaata ccgccttgat
    12841 ttcttcgaga aattccggaa atcgtgtccg caacttgtct accttgacga ttggctggtg
    12901 aagcaagaga aataagtgca tcttttccag tgatttgctg ttttacaacg atagcatccc
    12961 ccaccgcata aatatcagga atattcgttt gataacgttc gtctactagg atacccccgc
    13021 gtatgcctaa ttcgattcca gcggtcactg ctagctggtt atcaggacga acaccaatgg
    13081 ataaaataac taaatcagca gggatggtac gcccatcatc cagtcgcaat cgtttcccgt
    13141 ggtcttcaaa tccagcgaca gcatgagaag taatcacttc tactccttga tgagacaatt
    13201 ctttttctat aaaagctgcc atttcttcat ccagtgttgg aagaatatgt ggtgcttgtt
    13261 cgatcaccat gacttctaaa cctcttcttt ttaggttttc tgccatttcc aatccgatga
    13321 atcctgcacc aacgatcacg gcacgctttg gctgtttttc taatgcatgc atcactttat
    13381 cgatatctgg tacatttcta atagaaaaaa cattgtcggc ttctgttatc cctggaatcg
    13441 atggaacaac tggttttgca ccaggagata aaaccaatgc atcgtactgt tcaatgtgtt
    13501 tttgaccctc atgtacgact tctaccgttt tgttttcggg aaagatggct gtcacttcat
    13561 gatttggacg cacatctaaa caaaaacgag cggataatga ttctggcgtt tggacaagaa
    13621 gattttcccg ttcactgatt tctcccgaaa gataataagg caagccgcaa tttgcaaaag
    13681 aaacatacgg tcctttttca aaaacaacga tttctgcatc ttccattaat cggcgaagcc
    13741 gtgtagcagc agacattcca cctgctacac ctccgacaat aacgattttc atcttatttc
    13801 cctcctactg ttcgatcaaa ccattgattc atgccaccac gtacattcac tacatcataa
    13861 ccagatttct ttaattcttt agctgcttgt ttactcctca tccctgattg acaaatcaca
    13921 tagacggtct tttctttgtc tccatcatat ctgtttatac tttgtaatgg aacattttta
    13981 gctcctttta tatgcccgcc ccggtattct gcaggtgttc taacatcaag taacgctgga
    14041 ttttccaaaa gcttttcctt taattctggg actgttatcg attttattga ttgaaatagc
    14101 aaattcattt tctgcacctc atttacattt ttataaatac ctcatggggt atattaaaca
    14161 ggagctttat taatatgtca accagaatga ctcttcattt ttttcactac tttttatatt
    14221 tgcataaaat accgataagg ggtattatct aattataaaa atagaggaga atgtgttatg
    14281 gagattgata ataaaaatat cctgaaccgt ttgaaacgta cagagggaca aattcgtggt
    14341 atccaaaaaa tgatcgaaga cgaaaaagaa tgtatggatg tcatcactca attaagcgct
    14401 gttcgttcta gtattgatcg cgtaatgggc atgatcgttg cagataatct gaaaaattgc
    14461 tttgagaaac ctgatagtaa tccagaagaa caagcggcta aactagaaca agcgatcaag
    14521 atgattatta aaaagtaaag gaatgatttc aatgaaagtc gttttccata ttgatgaatt
    14581 agaaaaatgg tcagaaacag ggaaaaacgt aaaaaacctg ataaaagctt ctccagaaac
    14641 gacgattgtc gtatctgtaa atggcatcgc gattaccggt tatctagact ctgccaatgc
    14701 agaattctta gatttgcaag gagtcgtttt tcacgcttgc gccaatgcta tgcgtgctaa
    14761 tcatatttca gaaagttctt tacctgaaca agtaatcgtt gtaccagcag gtgtccttga
    14821 tttagttgaa ctgcaatccc aaggttatgc ttatatcaag ccttagtcag tagaggttgc
    14881 gacagaagtg atcagcttca agaaatttcg gcttattttt cgaagaagct acttctggaa
    14941 aaccgtgaat caaaggttgt gaaaacgctg tcctgcatca agtaataaga acagccaaac
    15001 aaaaatagct tctcatattt ttcgtttggt tgggcttatt accgcagatg caagcttttg
    15061 aacaccgttt aaggaagagg ttgtgaaatc agcggtttga cctaagtatt agagaaaaaa
    15121 acgggaaaat agctcctcat attttgccgt tttttgagct aataccgaag gtcagctgat
    15181 tgaacaccgt ttaaggaaga gattgtgaaa aagtcgctta gtttcgagta ttaagaaaaa
    15241 ttttgtgaaa atggatttct acatttttgc ataaatttgg cttaataccg agaaactggc
    15301 ttttgaatac cgtttaagga agaggttgta aaatcagcgg tttgacctga gtattagaga
    15361 aacaaacgga aaaatagctg ctcatatttt gccgtttttt gagctaatac cgaaggtcag
    15421 ctgattgaac accgtttacc aagaggttgt gagcctacca tttaactccg aatcacaaga
    15481 aataatttca aaaacaactt ctcctgtttt tggtttggtt ggcttattat cgagaagtag
    15541 ctactgggag tctatttatc aaaaaaagga atgcgacata ggtcacaccc cttttttatt
    15601 ttctttgaaa catctttcgg tactcgacag catacaagac aaaagattgt aaaagaccgt
    15661 aagtgatgac ggcaaaaatg actctcaccc acagcgttgg taattctggg aaaagcagca
    15721 aaaggatcat gccaacatag atgacagcag tcgctacttt gccataccac ttcgctccac
    15781 ttaatttgat atttttagat agcccgatta atccagctac aaacataaag ccttctttta
    15841 tcaagaatag accaaacaac agccaaagcc acggtcgata ccatgccata gacaaaatca
    15901 gaaaaagttg tgtcaattta tctgcaaacg gatcaagcac cttccctaag tctgttacct
    15961 gattatatct ccgagcaatg accccgtcta gataatcaga caaacctgag acaacaatga
    16021 ccgctcctgc tatataaaat gactgtctca gcacaaaata aagataaatc ggcagcaaaa
    16081 aaatacggaa tatcgataaa agattcggaa tcgtttgtat ttctttacgc cagtctgtgc
    16141 ttaatttcat tttatcgccc tacctcctca gcactctttt ctttttattt tagcttacac
    16201 ggggaataaa accaatgatt tcactgtttt tatttttctt tacagccact gatattatga
    16261 gctaatttga gataatcact tgctgttttc atcgtttact cttctttctt cctgtcgttt
    16321 gcgcatttct tttactagta ctttatgagc tttttttgat cctcgctcta ggtcacgctg
    16381 ccgtttacgt gttttataat cgataaacag actgtctaaa tcgtaacctg tcgggtacag
    16441 atcttctgct gaacgcacca gacgaacacg ctgacgaggc acgtggatta tttttttgtc
    16501 taaatataca tcaatcgtat cttcacctat atcttcataa actaacgctt ctttttggta
    16561 ttcattgaca aatatccgat caccttttgc aaagagctgg cgttcttttt tattctcctt
    16621 cctatttgta actgctgtct taggaagaaa ttcttttttc tgtgtccgat aggctttttc
    16681 cgccaagtaa cgctctgctt gatggatcaa tttcatcgac atatccattt tatgagcaat
    16741 ccacaaagct tggctttctc ctgtttctcc aacccgcaac tgatatttag gacgaagtgc
    16801 ttcccgatcg aaagccatag cagccggcac aaaatcttca tgatctccgg cgaatttctt
    16861 gatttctcca taatgggtcg tggcaatgat caatgcccct tgctcataca tagattccat
    16921 gattgcgatc gctagtgcag ccccttcatt tggctctgtt ccactgccaa tctcatctaa
    16981 aagtaccaac gtattccttt ttatcttttt caaaatagca gcgatgtttt gcatatgacc
    17041 agaaaatgta ctcaacgcat tttctaaatt ttggtggtca ccgacatcga cgaaaatctc
    17101 atcaaagaca gcaagctctg tcccttcttt tgccggaact tgcataccga acatcgccat
    17161 caaagtcaat aaaccgactg tcttcaacac gactgttttg cctccggcat ttgctccggt
    17221 gataatcaag cctcgatagt ctttaccgat ttcaacatcc aatggtaccg catgctcagg
    17281 taaaaatgga tgtctgcctt gcttgataat gatatgttcc gatttattga ttctaggtgt
    17341 gcttccattg atttctcggc taaattttgc ccgagcaaag atgatatcta acaccgtgat
    17401 cgtttcgatc aataaatcga tcacttcttc gttttctgcg atagcaccag tcaatgccgc
    17461 caggacttga tattcttcac tgatttcttc agcttttaac aactgatagt gttcattcaa
    17521 tttagaaatc acagttggtt caataaaaac cgtcgttctt ttatttgatt catcgataat
    17581 cgttccatct attttatttt tatagctggc tttgatagga atcgtatagt attcgccttt
    17641 ttgaacaatc attgcttctt ggatcatttc tttgtttttc ggatgacgca agaatttcag
    17701 taattttgac tggatttctt tttcgattag ttgtaattgt ttgcgtactt tacgcaaatt
    17761 acgtgacgcg tcgtcactga ctttattatt ttttattttc tggtcaatca actcttctac
    17821 atttatcaaa tcaggaagat gtttgctata agcaaacaac aagggtgtct ggtattgatt
    17881 cttatcaaaa aactttgtga tcatccgact gcttctaaga aaatccgcat attcgatcaa
    17941 atcggttggc tgcagaatca accctttttt gacttgttct gtcagtgcat cgatcctcgg
    18001 caaccccata aatggaacat gctgactgct ttctaagatc aagcgtgctt ctcttgtttc
    18061 ttcttgacga tccaagacag tttgtaggtt tgtcgagacc gtcatatcgc tgattcgttt
    18121 tttgctatag tttccaattg ctcttgcttg gatttccttt ttgatccgat caaattgtaa
    18181 ttgactaatc atttcgttgt ccatattctc tccttttctt gaagagatac ctgtcccaaa
    18241 ataaataagg gcctagagat aaataaaagg atagaacaca gcttaaaaaa gtcatgtcct
    18301 atccttatta gaatacaaag atattgtttt cctgacaggt accgtttcat aagcacacca
    18361 aataaacttt gtttattggc tattcgactt actgattaga taccagctac actcacaaaa
    18421 cataccccat tcttctaggt cttatttatt ttccacttaa ctatagcaag acacattttg
    18481 gttgtcaaac tttagtatgt tttatagatt tacaccatta atgaatagac acctaccgcg
    18541 ataattgctc cgatcattgg acctgcgatt ggtacccatg aatatgccca atctgaagtt
    18601 cctttattag ctattggcaa taccgcatgt gctaatcgag gaccaaagtc ccgagcaggg
    18661 ttgattgcat atcctgttgg ccctcctaat gaaagaccga tggctaagat caatccacct
    18721 acagcgaata cgttcgttcc aggtgcaaat tcgttttgtc caaaagctag caacccaaga
    18781 actaatacaa atgtaccaat taattctgtg atcacatttg ctggataatt ccgtatagca
    18841 ggacctgttg caaacgttcc taaaatcgcg ctttcatctt tcgttgcatt ccaatgtggc
    18901 aaataagaaa gccaaacaag aatggcccct gcaaaagctc ctaaaacttg cgcaatgatg
    18961 aaaggaacga caagattcca actaattgcc cctgtcatcg ccatagctag agagactgca
    19021 ggattcaaat gagctgggcc catgaatcca gaaatataga cagccattgt tacagcgagt
    19081 ccccaaccaa atgcgatgac aatccagcca gaagcctgtg ctttactttt gtttaaattc
    19141 acagccgcac acacaccatc tccaagcaaa actaggatca gtgtcccaat aaactctccc
    19201 atgatttgag tcatatcact gttcatttat ttctccccct ttagttcccg cagatctgat
    19261 tctgcaatca atgcttctaa acgtttagtc tgttgcgcct tctcctcttc tgtccattca
    19321 aaatatccag caattgcatc gatcacaggt tgcttgatct catcaagctg atctcgttca
    19381 aacaacagat gatttgtacg acgaatgaga taatcgcctg gggccaaaac catttcttct
    19441 tctaaaccat aacgtaaccg agctgactca gcgagactca aaccaggata aggtgccatt
    19501 tcttttgcta attcaaagat acgtcgggca ttagtcccgt aaaaatcagc gatataagta
    19561 gcatcttctt cctctaaacc ggctgctact ccttcttttg ctaattctgt cactgtttct
    19621 tctaatttag ttggatcgaa gtttccacct gaaatctgat attttttaga gtcgatttct
    19681 ttcgtctcta ttccgtattc ttcttttaat aattggcgta tcaatcgcaa agctccttct
    19741 gccatcttac ggtaatcggt gattttccca ccagataaag tcagcaaacc atctggttct
    19801 ctttctaaag aactacctct ggaaatcgta gaaggtgctt tttcatcacg gctgttttcc
    19861 aaatggttca acacgtcttc tacttcagca cgagaaactt tgttttcctt atattcactt
    19921 actgtatcga caactttatt gaagctcttg tctgaaatcg atccattatc tccaccattg
    19981 taatcagaac cagaattacc aatcaacagt ggacgaagtc ctgcccagct tgcttcgata
    20041 tcattcaatg tgatatttgc ttctggatag cgatgattga tcacatccaa tagataatct
    20101 acatcttctt gtgtgacttt cggatccgta aaatctcctt ggtaatccgt atctgtcgta
    20161 ccaaagtaag tcttgttttc tcttggaata gcaaaaacca tccgcccatc ttgctttcct
    20221 gtatcgaagt atgtgggttg cggtacaggc agttttttcg catctacaac taaatggatc
    20281 cctttagttg gacgcatttt aggagagact ggacgcgtaa aattcaagtt tcgtacttta
    20341 tctacccaag gaccactcgt attgatcact aattttgctt tgatttcgat cacttcatct
    20401 gtcagcaggt cacgagcttt gacgccaacg atttgatcgc catcatataa aaagccaacc
    20461 gctttcattt tacttactag ataagcccca tcttcggcag cctttttgat attatcaatc
    20521 actaaacggg catcattgtt gcggaaatct agatagacac ccgcgccttt tagcccttct
    20581 tttttcaaaa acggttctct ttccaatact tcttctggtg tcagcgtata attctcatat
    20641 ttggttcctg tcacatttgc cagtttgtca taaaggtcca ttgctacttt gaccgagaac
    20701 atattgaagg ttgttgctcc ttcgccctca tagattggca aaagcattgg atctggtttt
    20761 gggatgtgtg gggcaatact ttgtacgact gcacgttcac caactgtgtc agctactact
    20821 tccacatcaa atgtcttcag ataacgaata ccgccatgaa caagtttggt cgagcgagag
    20881 gaagtccctt ctgcaaaatc ctgcatttcg atcaatcctg ttttgattcc tgatgctgct
    20941 gactggactg ccacaccggc accagtgatt ccgccaccga tgatcaacag atccaattct
    21001 tcttgctgca ttttttgaat gctatcttgt cttgtcttgt ttgaaaacat atggatttcc
    21061 tccttattca aatgcttggg tagcttttac tgcttttttc caaccgttgt aaagtttttc
    21121 tcggcgctct tcctccattt gaacttcaaa tagcttgcca gcttcataaa attcgcggat
    21181 ctcgtctgta tctttccaat aaccgacagc taatcctgct aaaaatgctg cccctagcgc
    21241 cgttgtttcc aagttttctg ctcgttggat cggtacattc aagatatctg tttggaattg
    21301 catcagatat tcattgtttg ctgcaccgcc atctactttc aatacaggaa tcttgattcc
    21361 agtgtcatct tgcatcgtat cgatgatatc tctcacttga taagcaatcg actgtaaagt
    21421 agctttaatg atatcttctt ttgtcgtacc acgtgtcaag ccaaacatag cccctcgtgc
    21481 tgcctgatcc caataaggag cacctagccc aacgaatgca ggaacaacat aaacctcatc
    21541 ttcgcttgta gagcgtttcg ctgcgtcttc tgaatcgcta gctttttgca acatttgaag
    21601 tccatctctc agccattgaa tcgaagaacc agccacaaaa atacttcctt ctaaagcata
    21661 gtaaaccttt ccatttatgc cgtaaccaat tgtcgtcaat aaattatttt tggataattg
    21721 cggtttttca ccggtattca tgacaataaa tgaacctgta ccataagtat tcttgaccat
    21781 gcctggttcg aatgccattt gtccgaataa tgcggcttgc tggtctcctg ccatccctga
    21841 aattggtgct tcgcttccat aaaaatgata accttgcgta taaccataaa cttctgagtt
    21901 agaagtgact tttggtaaca tcactcgagg aatatttagt aaatctaaaa tctcctgatc
    21961 ccaatctagc tgatggatat tgaacaacat cgtccgactg gcattcgagt aatcagtaac
    22021 atgtgcttgt ccatcggtca gtttccatac taaccaagaa tcgatcgttc caaacatcaa
    22081 ttcgcctttt tcagctcgtt cttgcgcgcc ttctacatga tcaagaatcc agcgtatctt
    22141 cgttgctgag aaataggcat cgatcactaa ccctgttttt tcgtggaaaa attcttgata
    22201 gccttcattt tttaagttat ctgcaattcc agctgactgt ctggattgcc aaacaactgc
    22261 atgatagatt ggacgtcctg tatctttttc ccatattact gttgtttcac gctggttcgt
    22321 tatgccaatc ccagcaatct gatttggttt gatccctgat tcgatgaacg ctccggcaat
    22381 aactgactgt acagaattcc agatttcatt tgcatcatgt tccacccaac tttcttgcgg
    22441 gaaatattgc gtgaactctt tttgagaact gccgatgtgt cttcctttct tgtcaaagat
    22501 aattgctcgt gagctagttg taccttggtc aatcgccatg atatacgttg attctgtcat
    22561 tgtgattccc tccattatat gcaaacgctt tctttaacta ctcttatcat actactgttt
    22621 taaaaaaaga aactgtcaaa attttattct ttttttcttt ttttgacagt tttttattat
    22681 gaagctattt tttaatcaat tcttttcttt tttcagcgtc tctattcttc ttttcaatcg
    22741 aataatgtcg taaggtgacg caaattctga cagataatat tcacactgtt ttttgtttct
    22801 ctggcaaaat gtgatcacca aatcatattc tttaccttct tcataacttc caatctcaat
    22861 accgccgatt cccctcagtt ctctgatcag atattgttga aaagcaatac gataaatcgg
    22921 cagactttct aaatcgattc caatcactac tggttttgca atataaaaat cgatcatcaa
    22981 aagaacattg gcatactgga tcatcaggta actaagctca ctatcttcag ctcttttcct
    23041 cggcaattgc tgcaccgctg tttcctgtaa tttcgccagt aactgtgtta aggaatgccc
    23101 gagcattttc tgctgctgtt ccaaaagccg atcacgctca tagacttcga tctttccaac
    23161 aaagaaaaac cattcattgt tgatctggga aatttggtag cctactgcct tttcttcttt
    23221 gattttcaaa cgacgaggac gataatgcca taacatcgtt tcccgaatgt aagtatctaa
    23281 aacagcggtt ggtaactttt tgctccgtgt caaatcatac tgataaaata tttcttcgtc
    23341 tactatcgaa aaagaaacaa aaaagctgta aaacatcatt gtttcgtata cattcagttc
    23401 tgctgctgtt cgactaagat gcatcacgat gattggatcg attgcttgat aaagccggtc
    23461 cgactgatag agtaatttct tttctttcaa agttgcgtac gtactttttt cattcaatag
    23521 tctttttttc gtaatcccga gccagcaagc aatctgtgct tctgctgatg ccgtaaacgt
    23581 tgtttctaat acacggtcca atcctagaat gaacggtctt ttttctggtg tattttgcaa
    23641 aaaaagcggt cgctgatctt ccgggatata ttggaatagt tcataataaa aatatcgtat
    23701 ctgtagctct tctccgtata attgaccgtt tttgatttgt aatccaaatt cctctaagag
    23761 ctggttcaat tctttgatct ttcgaaaaac agaagactca ctgatattaa acgctgtcgc
    23821 taatcgaacg atggatactt gctgatgttc taataaatag acgagcatct taaacttcaa
    23881 gctttcctgc aataaaaaca atagaatttt ttccaaactt acatcttcgt ccaacacaag
    23941 cagcgcctga tactcatttc gctgtacttc tacttttttt tccatcattc ggccaatcaa
    24001 ttcaatatct tccaaatatt gatcaaacga ggcttttgac agttggacat gctctctcaa
    24061 accattgata gaggctgttc ccccttgcag aacaaggttt cgcaaaatca ggatctgtaa
    24121 ctgctctttt ctttctaata atgcttcaat cttcataggc agtattcgcc acctttgacc
    24181 acaccatatc tggcacacgg tattctggct ggaaaaatag ctcatgttct tctaactgtt
    24241 caaacgtcca tccttcttct actgcaattg tcagttggtc aagaaggtgg aacatctctt
    24301 ttttgctttg gagctgtgct ccaagaatct ttttttcaga atcaaataga aatttgagtt
    24361 taactttgct ttgatttatt gctgtaagct tgtagtctac gtatcctgtt tcaatttttt
    24421 ggggataaaa aatgctctct tcttctgtca aacctacgct tcctaagaaa tagccaaacc
    24481 actgattgcc gactggacga taggttccct gatcctttgt ctgtgagcca ctaattgtct
    24541 tgctgacatt tcgtgctgta cggacagcgt tatttactag agaaacatac attttttcat
    24601 ttgttggacg aaaagttact tggatcgcat cgccaatcgc ataaacgtct ttttgagacg
    24661 tttgcaagta gtcatctacc cagatcgttc catcatcatt caatgttaat tgttcttccc
    24721 acatctgatt gtcggggcga gaatgattag ccagcaaaac aagatcatag ttctcctttc
    24781 ttttttccgt ctctacaata gcggtttcat tttcggtcaa agacacaact tgttcttcta
    24841 aaaaaagtga aagcccttga tttttcattt cctttactaa cggttctgtc atttcaggat
    24901 ctagataacg aaaaagaatt gactttcggc tttcgtaaag atggatttgt ttttttcttg
    24961 atgccaaccc ttcagctatt tcgattcctg cttgtcctgc accaataatt gcaattttct
    25021 ttgcattcat gatcttttgc tgaagagccg ttacgttttg tatcttttta actgggtgaa
    25081 taagcgttga ttctgcagaa atatttcgaa acttttgatt tgaaccagtc gctagaatca
    25141 aacgatcaaa atccaatttt tttcctcctg ctaaaacgac ttttttttct ttcaatccta
    25201 ttactgtctt ttctgtgtaa acatggattc gatagcggtc agtcagttct tctttcgtga
    25261 tccaagaaag ttgtttttca ctggtaacct ttccttttaa tatcaaattg aacccgctgg
    25321 gaatccatcc taacttcgat tgcttttcaa tcaaatatat ttcacttgtt ggcatcaatt
    25381 ggcgaagata aatagccgca tgaatccctg caaacgaccc gccgacaatt acaatgttca
    25441 tctgcattcc tctttcttat aaggtgttct actgctaact tctcaatcag aaaacacagt
    25501 attcataact cgctttcaac cttatgatac atagcgatgc agcagaatca accctctcca
    25561 tcataccgtg ttctaggtct gcttctcaat aatgtactag tggacctaat tgaagagtat
    25621 catttctgaa gagatgtttc aaaaaatgta ctcttataaa agaaaaaaac tcgcctttta
    25681 cgtacctctg tccaaatagg aaacagaaaa gaacgaaaag acgagtttta gcgtgtgtaa
    25741 tgtaatagtt agaatagaca catcatttat ttttaattct ttaatgcttc aacaactgct
    25801 tcgcctaatt gatgagcaga ttgaggattt tgccctgtaa gaagccgccc atcaatttga
    25861 accacttctg aaaaagctgc tccagactga tagtttgctc ctttttcttt caaagcatct
    25921 tctgctaaga atggtacttc attcgttgta ccatttgctt cctcttcttc attactgaac
    25981 ccagtcactg tacgtccagc taaaatagat tttccagact catctgtaac tggcaacaat
    26041 cctacaacac cgtgacaaac agctgagacc agcccttcat ttcgatagat ttgtgaagcg
    26101 actttcccaa gatctattgc ttctggaaaa tcccacattg ttccgtggcc accagcataa
    26161 taaaccgctg cataatcatt tgcatccaca tcatcaggac gtaaggtatt tcccaaggcc
    26221 cgatttctga aatcttcatc ttcataatag gcccaatcga tttcatccat attcaaaaca
    26281 ctttgcggtt ctaaaggtac atatccgcct ttaggactga caaaatctgc atcgatccca
    26341 ttttttacta atacatcata aaaatgagtc agttcactta accacaaacc tgtaggacgc
    26401 tcgatctttt cgtacttttc tacatttgtt aatacgatca atactttcat tttcccatcc
    26461 tctttctata aaaattgcgt tattgataac gtgctttcaa gaaattatat aatgggcttg
    26521 gcaaataaag ctctttatat gcttcttcaa aaggtttcgt tacaaattca tcctcacggt
    26581 tttccaataa tttctctgcc cagtcaggat cgacgatcat ttgctgtcca attgctgcaa
    26641 gttctgcata tttcaatacc tgctctacat cttcgcgatt gcggatccca ccgacaccaa
    26701 ctaaagggat ctttccttga atcgtgttat ggaccacttc aagaatcgat ttatcgttgt
    26761 atttatcaga acgagctatt cgatcataca tatttaatga aacatgcaga taatctagtt
    26821 ttgactcacg taatcgttca agaagccaga tcgtgtcttc aaaacggata cctggtgttt
    26881 catattcttc tggtgagaaa cgatacccta cgatgaatgg ttttttagca tattgttcaa
    26941 ccgctgagaa aaccgttgtt aataattctt caataaaacg ataacgattt tccaagctac
    27001 cgccccattg atcctctcgt ctattcgaat gcggagagaa aaattgttgg atcaaatacg
    27061 tatttgctcc atgcaactcg attccatcaa atcctgattc aatcgctcta cgtgtggctt
    27121 tgccaaatgc ttggattgtt tcaacgattt cttcttcact cattgctcgt ggtgtttccg
    27181 catcaggacg ttttgctgca actgcacttg cagatacagg ctgttctcca gataaagttg
    27241 ctcgacttgt cattcgtcca ccgtggaaaa tctgaataat cgcttttgcg ccttctcctt
    27301 ggattgcttt cgctagctca cttaatcgag gaatcatttc atcatgagcg atgctgagtt
    27361 cacctggcca gccttttccg atatcttgga catttgcagc accagtaata acagcaccaa
    27421 gacctttaga acgttgttta taataagtga tctcatcttc ggtgatcact ccattgaaaa
    27481 agctgagttg tgtcgtcata ggcgacagca tcaatcggtt cttcaattga actcctgaag
    27541 gtaaagtaat tgattgatca aattgtgaca ttgtcattcc tcccataatt cgctctgatt
    27601 aacctatcga gaatcatcta tcattaaacc actcgattag ttgtacatgc aactaatttg
    27661 cttaaaaaat tttatttttt ttgtaactta tctgttgcat cattcattgt ctgggctaat
    27721 tctttacttg cttcatttcc caaaactgct ttgtatgact gatgaagttc ttcccagcta
    27781 ccatcgactt ccttagcaaa ttggcgtcct tgttctgtaa gataaactaa tgacaagcga
    27841 ccttcgctaa ctgttttgac gtatccttta tattctaatt tttcaacaaa acgagcaatc
    27901 gttgatgggg cggaatagag catttgtgca atatcttttt gtggtattcc atctttttct
    27961 tttaatatca ataaaataaa accataagtt ggtgccagac ctgtccttct aaacgcttca
    28021 tcagctaatt tattcaacat gcgatctagc tttttcacgc taaagaaaag acattcatct
    28081 aacgcttttt caattggctt ttccatttca tcccctccat tggcgtacat atcatagtat
    28141 gatttttatt ttttgtcaaa aaacacggaa taatgtccgc ctcctctgtc tagatttgaa
    28201 aaaaagaagt agccatcttc aaagaatttc ggcttgtttt cgacaaaact ccttctggaa
    28261 caccgtgaat cagaggttgt gaaaaagtcg tttagttttg agtatgaaga aaaattttgt
    28321 gaaaatggct ttccacattt ttgcataaat ttggcttaat accgaaaaac tggcttttga
    28381 acaccgttta tatcagaggt tgtgaaaaag ccgtcctgca tcaagtaata agaacagcca
    28441 aacaaaaata gttcctcata ttttgtcgtt ttttgagcta atgccgatgg tcagctgatt
    28501 gtacaccgtt tattgagagg tcgtgagcct gccgttgaac tccgagtcac aaggagcaat
    28561 ttcaaaaaac agcttctcat gttttatgac tatggtgact tgtgatcgag gagttggcag
    28621 gagaatactg tttattcgta aagaaggggc tgtgacaaga cttttgtcac agtcccttat
    28681 ttccttttat tataggattt cgccatttga ttggatgact tgtctgtacc aatcaaatga
    28741 ttttttcttt aaccgtttct ttgtgccatt cccttcgtca tcttgatcaa catagatata
    28801 tccataacgt tttgacattt gtgaagtaga agcgctgacg atatcaatgc agccccacga
    28861 cgtataacca aataaatcta ctccatcttt gatagcttcc ttcatctgct caatatgctg
    28921 tttcaaatag tcaatgcggt aatcgtcttg aacggttcca tcttcttcta ctttgtctat
    28981 agctccgagt ccgttttcag ctatgaacag tggtttttga tacctatcat ataattgatt
    29041 caaagcaatt ctcaaaccct taggatcaat ctgccagccc cattcacttg atggaagata
    29101 cggattttta attcctccag ttattaagtt tccttggacc ccttcccaat tttctggatg
    29161 agcactgact gcactagaca tgtagtagct aaaagaaaca aaatcaacag ggtaggctgc
    29221 taagatttct tcatcaccta cttctatttt taagttgaca cctttttctt caaacattcg
    29281 ttgcgtatac gctggataat atcctcttgc ttgaacatca ctaaagaaca aagaagttct
    29341 ttgctgctca attgtttttt gaatatcatc cggatcacaa gaatacggaa caagaagctg
    29401 atagctgatc atacaaccga cttgtgaacc tttgataatt tcatgacaag cttttgtagc
    29461 taaagcactt gctataaact gatggtgtgc accttggtat ttcgcttgtt ccaaatgggg
    29521 atggttttct tcaattactc ctacgctaac aaaagggtga tgttttacac agttgatctc
    29581 attgaaagtc atccaatatt ttactttatt tttatagcgt ttgaatactg tttcagcgaa
    29641 acgaacgtaa aactgaataa gctttcgatt aggccatcca ccatattctg taaccaaata
    29701 taacggcatt tcataatggg aaagagaaac gactggctca atcccatatt ttagacattc
    29761 gtcaaacact tgatcataaa aaaataatcc cgcttcattg ggtgtttctt catcaccatg
    29821 aggaaaaatt cttgtccatg cgatagacat ccgatagcat ttaaaaccca tttcagcaaa
    29881 taaacggatg tcttctttaa agtgatgata gaaatcattt ccgtgtcttt taggataata
    29941 atacttgctg ttgggatcct gcgccgcttt tacttgctga tgcgtcatca tatgccattg
    30001 atctgtccat ttttctttag gtaaatcgct gtcgaatgta tacacatcag acacagataa
    30061 tcctttttca tctacatccc atgcaccttc acattgattg gccgctgtcg ctccgcccca
    30121 taaaaatcct tctggaaatt ttttcatatc gatcccccta aacttgctag ttttcttgtt
    30181 tgattatttt tcttatgact agtaatgata tttttgaatc tactactatt tgtaacaata
    30241 accattgtgg tcggatcata tccctctttg attaattctt gcaaatctac ttccatcaat
    30301 aaatcgcctt tacgtacttt ttttccatca gatactgcac tttgaaagta tttgccattt
    30361 aaattcactg tatcaatacc gatatggatc agtatctctg ctccttcttc actgactacc
    30421 ccaattgcat gtttcgttgg aaaaactgtt gaaacttccc cgtttacagg actgtagatt
    30481 tttccgtccg ttggaatgat cgcaaaccct tctcctaaag atccactagc aaatgttgga
    30541 tcgtttactt cagataaatc aattatttca cctgctgcag gagtacttaa cactatatcc
    30601 tttgaggatt cttcttcgat ttcatccttg tagccgaaaa gaaaagttag catacaggaa
    30661 ctgatcatcg ctaagaaata actagcaact agccaaacaa atccttcacc aatataaatc
    30721 gggaaagaca aaatacttct tgtagcaact gccaaagcac cggctcctgc ggcaccagct
    30781 actccaccaa atatagctcc acatatacaa gcaatgtaaa atggtcgttt atatttaaga
    30841 gtcacaccat aaacagcagg ttcagtgatt ccaaataatg ctgtgataaa tgcagataaa
    30901 gataaacttt ttactttctt atttttcgtt ttcaaaaata ccccaagtac tgctcctgct
    30961 tgcgcagcta cggcagtcat acatgctgga cctagcgtat cacgaccgta gaaagaaaga
    31021 ttgttggtca ttactggtac aagtccccaa tgtaacccaa aaatcactaa cacttgccaa
    31081 aatccgccga taacagcacc agataaaaca gggctaaagt tataaacagc taaatatcca
    31141 gctgcaatca gctgacttgc ataatctgca attggaccta caactaataa agtaattggg
    31201 accatcacga tgatacaaat gaatggtgtc aataaatttc gaatactttc gtgcaagctt
    31261 ttgcgaatct taggctcaat ataagaaaga acccatacag ctaaaattgc tggaataacc
    31321 gtacttgtat accttgctag aatcacgggc atccctagaa atcgcaaggt tatgctatca
    31381 ctatatgcac tgacaatcgt aggataaacg agagctgctg caataaccat agcgatgaaa
    31441 cgatctgtat tgaacttttt tgcagcagta tatgccaaaa atataggcaa gaaatagaaa
    31501 aatgcatcag ctgctgcatt caaaatgata taagttcctg attcagtagt taataaattc
    31561 aaactcgtac ataaggcgag tactcctttg atcaaaccac ttcctgccaa gacgcctaaa
    31621 gtcggggcaa aaacagcggc gatcatgtct ataaaagagt ttaaaatgcc ttttttctca
    31681 gttcctctct ttccactaga tgcatcatct tctagtttca tttgtttgga taatacgtca
    31741 tacacttcat ttactgcatt tcctactacg acttgaaaca ttcctccagc ttcgactaca
    31801 gtgatcacac cttctagttg ctctaccttc tccttatctg ccttcttatt atcttttagg
    31861 gtaaagcgta accttgttgc acaatggtaa acattgctga cattttcttc gcctccgaca
    31921 aatcggacaa tatctttcgc taattgtgaa tagtccattt ttacttcccc cttgttaatt
    31981 aatgccgtag caatccttct tacaagataa gtatagttct tagaaaacgg tttctccatt
    32041 caattagtac cccttataat agcgaacgaa actgtacaat agtgtgtatg gtttacttag
    32101 ccgagcaaat cactcactgc ttgaaagaaa acaagtatat cgtttctctt atagtcaaag
    32161 gagacaaaaa aaacacgctt gatcttcctt tgctgatgta taagtggtat ctcaagctga
    32221 tactctgtga tttttgtttc tacttggctt ttgataagac agcacaacaa agtctcggca
    32281 tttaacggaa gcataactag gtcagaacta ggagagatta gttgctgaat ggaatctatc
    32341 tttttatgga tttttatttg attttcttct ttgtagtaat gatcaagcag ttttgttttc
    32401 tttttttctt caactatggt cagcttttca cgcaaaatct gataaatctc ccaagattca
    32461 aactcatcta gaacactagg tagataaatc aaatcatccc actcaaaaat aagctcttgc
    32521 tcagtagtca aaattgcatc atattccgtt attttgtttg attgattttt gaaaagatac
    32581 actggttcta tccggcattc tttgatccac atgttcatac tttgttgaat ctgttttttt
    32641 agtgtattca aaatactaat tggctggtta ctaacaatca gtatctcccc ttgttttcga
    32701 aaaggattca acgcttcggc aagatacaaa acaaaataag cgctttcagc taaattggga
    32761 cgtaattgaa aatgtattgg gaagaaacgc cgaattaaat aaatttctaa aggataacgg
    32821 gagatgatct tttgtacaaa atgattcatg gtattatgtc cggcatccat cctcgttttc
    32881 atttgtttga tatgggttag caaaaattct gtttcatgga acaataacga aacaggaaga
    32941 tctaaaaaac gaataatcgt ttgctcaaat gctcttagat tcttctctat ttctttgttt
    33001 ttttcatcat taatcatcaa ataatttaac tctaatagtc gattttcaat tgcttgtttt
    33061 tcttgattgg aaaaagaata gggtagttct gatgataact tttttgtgag ggtctctacc
    33121 atcggaataa ataatgtata cctgtttgtt ttttctaaaa gttcttctct tcgaagaatg
    33181 gtcaaaacga gataccgaga aaatcgtatg aagtcctctc ctgaaacaat ataattatat
    33241 gatataagaa cctcttttaa tgtcttttgg acagtcggca tgatattgga aaaaattgta
    33301 ctgatttgtt gaggcaacct tgcgtgttgg atcaccgttt ctgttccaac aagagataag
    33361 aaaattcttt ttgaattttc ttcagcaatg atttttagtc cttttgtcga cgaaacttcc
    33421 agttctaatt taggattgcg ctcgatccaa cgcaaaatcg tttttatttg taatgatacg
    33481 gctgtttttg aaagaaagaa aatgtctgct atcttttgca tactgacata ccctttttga
    33541 aacaataagt acgtcacaat agttgaagct cggaaatcca tgctggaata gattttatgt
    33601 ttcgtcacct cttgtatgat ttgctgttta gtttcagatt caattgattc taaaaaataa
    33661 cctgaacgtt tatttgactg gataatgatt ttcttctcgt agatagcaag catatttttg
    33721 atttcagttt ggatcgtttt cttgttggta cctaaagctt cagctaattc ttcgcttgtt
    33781 atccaatgat tcttatttct taatactaca agaatttgga gttgtcgttt atttaagtcc
    33841 atttgcttac acctcctctt tgttataaac atacaggaaa aacctctcaa atgacaatag
    33901 tcacttgcag aggtttaaaa atcatttgaa gaaagatcta tattcaaggt ttttaccatt
    33961 agactggata atttgtttat aatattcaaa actatctttt ttcaatctcc taaagcttcc
    34021 gctcccatca ttttgtctat ccacataaat aaagccatat cgcttcctca tttcccctgt
    34081 tcctgccgat acgatatcga ttggtcccca ccataagtaa ccaatgattt ggcaaccatc
    34141 ttttattgcc tcagcaattt cctgaagatg tatttttaga tactcacaac gttttggatc
    34201 gtggattcga ttcaattcat ctggtgcttc atctagtcca atgccatttt caactatgaa
    34261 taatggtaat tcataacggt ctgtcaattc attcatgaca taacgaaacc ctagaggatc
    34321 aattggccaa ctccaaggtt cgggagattt ttccttcaaa aagggattat cgaaaccatt
    34381 tgctccgcca gtatctacgc gcatttctgc ttctttttta tagacagcgc tacgataata
    34441 actaaatgca atataatctg ccgtgttagc ttgcaagcac tgttcgtctc catctaacat
    34501 tactggtgca cagtcttctt ccttccatgt cctgtaaata taagctggat aatgccctcg
    34561 gcacatgaca tcggagaaaa accatgaatt gcgtttaaat tgcagtgaac caaatacatt
    34621 ctctggatca cagtcatatg cataagtcgc taatgcagaa aagctacaca taatacccat
    34681 cttagcattt ggatcgattt tctttaataa ttgagtagca cgggcgttcg ctagaaacat
    34741 atgatgacag gcttgataaa tcactttttt tgttagtgta gcaatgggtt caagtttatc
    34801 tctagcaggg aatgtaacca atccagcagc tgcataaggc atacgaaaag cattattgat
    34861 ctcattaaag gtcatccaat atttcacttt cccttggtag cgttcaaaga cggtctgcgc
    34921 ataaaattca aaaaagtcga ttaattttcg attttgccac cccccatact ctcctaccaa
    34981 tgctaagggg gtttcataat gactaagagt aattactggc tcgatatcat atcgatttaa
    35041 tgtattgatt agtctgtcat aaaatacgag accagcctca tttggcttct gttcgtctcc
    35101 tcttggaaat attcgtgccc atgagatgct tgttcgaaaa gcttttaaac ctaactcctt
    35161 cagtaaacga atatcctctt caaatcgatg ataaaaatca atcgcttcat gagaaagata
    35221 atggagtgat tcgtctaaag caatctccca aatctttttt tcttcattcc actgaatact
    35281 aggatgctgg ttcatgatcc cgataagcgt atctgtcaca ttaggtaatt tgccgtcttc
    35341 caaccatgca ccttcacatt gattagcagc tactgctccg ccccataaaa aattttctgg
    35401 aaatatttcc tgatccataa ctatctctcc tcgctatcaa caatttctta cttgaagtat
    35461 agctcgattc atcaaaacaa gatattctaa ctatttcggc agaagagaag aaaaaaattg
    35521 aatgctactc ttcattttta atatttatat ataacaaata cataagacga tccccgaaag
    35581 aaaacactcg ttaaccatct aagcaaacga tttattttac ttccaacaca aatgcttcat
    35641 aaggtcgtaa atcaactttg ccgtctggta actgtttcag aggataattt gacacaataa
    35701 cccttaaagc ttcacgtgga acagtgaacg tctgcttttc actggacata ttacaaataa
    35761 cgagccattg ctggtcttca tatatgcgag aataggcaaa gacatgctca ggcgtctttt
    35821 ccactaattc atagtctccc cagacgatga tgtcatgttt tctacgcaaa tcgatcaatt
    35881 tcttgtacat ataaaaaaca gaatcttgat ctgctaacgc ttcttctgca ttgatttctt
    35941 tataatttgg attgactcga agccatggaa ttccagtagt aaacccagca tgttcacggg
    36001 cgttccattg cataggcgtc ctagcattgt ctcttccttt cgcattgatt gattccaaga
    36061 tttcctcttt tgtaaatcca gaagaaatcc tttcgttata catattgatt gtctcaatat
    36121 cttttgcttc cgcgatatca tcgattgggc aattcgtcat gcctaactct tctccttgat
    36181 agatataagg ggtgcctttc atcatatgga gcaagatagc aaacatcttg gcactttctt
    36241 ttcgatacac atcgtcattt ccccaacgag aaacaattcg cggaagatcg tgattattcc
    36301 aaaataaact attccatcct tcatcaccta aagatgtttg ccatttggat aatacttttt
    36361 tcagttcaga gatactcaag ggtttcaaat cccatttgtc tttgccttct tgctgatcta
    36421 atcctatgtg ttcgaattgg aagaccatgg ataattcatt tcttttagga ttggaataaa
    36481 gtttagcgat ttcggtagtt gctccccatg tttcgccaac agtcatcaga tttttgtcac
    36541 caaaagttgc ttgattcatt tcctgaagat actcatgcag tttaggtcca ttacttgtga
    36601 tttctttatc cggttctttg ccaatcatat cgatcacgtc catacgaaag cccccaatac
    36661 ctttatcgat ccagaaattc atcatttgat aaatctcttg gcgaacctgt ttatttttcc
    36721 aattcaaatc aggttgacgc ttgctataca agtgcagaaa atattgcccc gttttttcat
    36781 ccaactgcca agcagaacca ctgaatattg agcgcaatct attaggctct tttccattga
    36841 ccggatcacg ccaaatataa tagtcccgat aaggattttc tttattttta cgggcctcaa
    36901 tgaaccacgg atgttcatca gaagtatgat tcaccaccag atccatgatg atacggatat
    36961 ttcttttctt tgcttcttca atcagttctt ccatttcttc catcgtaccg aattctgcca
    37021 tgattgcttg ataattactg atatcatacc cattgtcatc attcggagac tcgtatactg
    37081 gagaaagcca aattgcatca atacctaaat acgccagata atccaacctg gaaataatcc
    37141 cccgcaaatc tccaatacca tcttgatttg aatcttgaaa acttcttgga tagatttgat
    37201 aaacaactga atggtgccac catttttgtt ccatgatttt cctcctataa atggatgttt
    37261 ctattttttg cttaatcatt tattttagtc tctctcacta aaaattgtaa cgctttcaaa
    37321 tagctattgc accttgttat cggtaacaga ataaaacaaa aaaacagctg aggaaattcc
    37381 ctcaactgtt ttttgaaagg attgatttat gcagggaaga atgctgattt cacaacttct
    37441 ttataaacgg tgttcactca gctgtccctt ggtattagct caaaaaacgg caaaatatga
    37501 ggaac
//
LOCUS       DAFTHM010000017        37214 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFTHM010000017 DAFTHM010000000
VERSION     DAFTHM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37214
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.017"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            59..808
                     /locus_tag="L7C88_000866"
     CDS             59..808
                     /locus_tag="L7C88_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBP9557716.1"
                     /translation="MVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQ
                     SGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENR
                     LTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQL
                     VETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPK
                     TGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1232..1402)
                     /locus_tag="L7C88_000867"
     CDS             complement(1232..1402)
                     /locus_tag="L7C88_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9557717.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1596..1775)
                     /locus_tag="L7C88_000868"
     CDS             complement(1596..1775)
                     /locus_tag="L7C88_000868"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557718.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(1785..2009)
                     /locus_tag="L7C88_000869"
     CDS             complement(1785..2009)
                     /locus_tag="L7C88_000869"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557719.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            2162..3274
                     /locus_tag="L7C88_000870"
     CDS             2162..3274
                     /locus_tag="L7C88_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBP9557720.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3352..3645)
                     /locus_tag="L7C88_000871"
     CDS             complement(3352..3645)
                     /locus_tag="L7C88_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBP9557721.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3813..4127
                     /locus_tag="L7C88_000872"
     CDS             3813..4127
                     /locus_tag="L7C88_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBP9557722.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4148..6127
                     /locus_tag="L7C88_000873"
     CDS             4148..6127
                     /locus_tag="L7C88_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBP9557723.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6140..6466
                     /locus_tag="L7C88_000874"
     CDS             6140..6466
                     /locus_tag="L7C88_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBP9557724.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6482..7000
                     /locus_tag="L7C88_000875"
     CDS             6482..7000
                     /locus_tag="L7C88_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557725.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7000..8352
                     /gene="celB"
                     /locus_tag="L7C88_000876"
     CDS             7000..8352
                     /gene="celB"
                     /locus_tag="L7C88_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBP9557726.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8436..9941)
                     /locus_tag="L7C88_000877"
     CDS             complement(8436..9941)
                     /locus_tag="L7C88_000877"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBP9557727.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10033..10623)
                     /locus_tag="L7C88_000878"
     CDS             complement(10033..10623)
                     /locus_tag="L7C88_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBP9557728.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10802..12448
                     /locus_tag="L7C88_000879"
     CDS             10802..12448
                     /locus_tag="L7C88_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBP9557729.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12497..13216
                     /locus_tag="L7C88_000880"
     CDS             12497..13216
                     /locus_tag="L7C88_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBP9557730.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13695..14642
                     /locus_tag="L7C88_000881"
     CDS             13695..14642
                     /locus_tag="L7C88_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9557731.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14654..15574
                     /locus_tag="L7C88_000882"
     CDS             14654..15574
                     /locus_tag="L7C88_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9557732.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15615..17072
                     /locus_tag="L7C88_000883"
     CDS             15615..17072
                     /locus_tag="L7C88_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBP9557733.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17417..18031
                     /locus_tag="L7C88_000884"
     CDS             17417..18031
                     /locus_tag="L7C88_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBP9557734.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18024..19748
                     /locus_tag="L7C88_000885"
     CDS             18024..19748
                     /locus_tag="L7C88_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBP9557735.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELRELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19745..21196
                     /locus_tag="L7C88_000886"
     CDS             19745..21196
                     /locus_tag="L7C88_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9557736.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21669..23822)
                     /locus_tag="L7C88_000887"
     CDS             complement(21669..23822)
                     /locus_tag="L7C88_000887"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBP9557737.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23824..24870)
                     /locus_tag="L7C88_000888"
     CDS             complement(23824..24870)
                     /locus_tag="L7C88_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9557738.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            25020..26309
                     /locus_tag="L7C88_000889"
     CDS             25020..26309
                     /locus_tag="L7C88_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBP9557739.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26322..29024
                     /locus_tag="L7C88_000890"
     CDS             26322..29024
                     /locus_tag="L7C88_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBP9557740.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            29009..29866
                     /locus_tag="L7C88_000891"
     CDS             29009..29866
                     /locus_tag="L7C88_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBP9557741.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29937..30836)
                     /locus_tag="L7C88_000892"
     CDS             complement(29937..30836)
                     /locus_tag="L7C88_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBP9557742.1"
                     /translation="MVQLVCNCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            31005..33176
                     /locus_tag="L7C88_000893"
     CDS             31005..33176
                     /locus_tag="L7C88_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBP9557743.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIQPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33244..33585
                     /locus_tag="L7C88_000894"
     CDS             33244..33585
                     /locus_tag="L7C88_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBP9557744.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33861..35615)
                     /locus_tag="L7C88_000895"
     CDS             complement(33861..35615)
                     /locus_tag="L7C88_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557745.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35626..36462)
                     /locus_tag="L7C88_000896"
     CDS             complement(35626..36462)
                     /locus_tag="L7C88_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBP9557746.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(36464..37147)
                     /locus_tag="L7C88_000897"
     CDS             complement(36464..37147)
                     /locus_tag="L7C88_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBP9557747.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        12004 a         6543 c         7633 g        11034 t
ORIGIN      
        1 ggggtatgaa ttagatgcga caccgatcga gtttgagatc gaaagaagtc agacagcggt
       61 ggtagaattg acgaaagaaa accgacttac accaggcggt gtcgtgttga caaagatcga
      121 tgaccaaagc ggggaagtcc tgcaaggagc tgtttttgag ttacaagatg ccaatggaac
      181 cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgattg acggcttagc
      241 accaggagtg tatcagctgg tagaaaccca agcgccaacg gggtatgaat tggatgcgac
      301 accaatcgag tttgagatcg aaagaagtca gacagcggtg gtagaattga cgaaagaaaa
      361 tcgacttaca ccaggcggtg tcgtgttgac aaagatcgat gaccaaagcg gagaagtcct
      421 gcaaggagct gtttttgagt tacaagatgc caatggaacc gttctgcagt caggtctaac
      481 cacaggagca gatggaaaac tggcgataga tggcttagca ccaggagcat atcagctggt
      541 agaaactcaa gcgccaacgg ggtatgaatt ggatgcgaca ccagtaactt tcaagatcga
      601 aaaagaacaa gaagtggcga tctttttaac aaaagagaat agaaaagttg ctgatagctc
      661 agatataaga ggaaacaatc caacaagcag tggaaataag catcttccaa aaactggaga
      721 aaccatcatt agccagttta tattgtcaat attgggtgtg ctacttgttt tcatcagtat
      781 aaaatttaga aagaaacgaa atatatgagc taaaataaaa aattgaataa gcatagtttt
      841 taaaatcaac tagtacccat caattgaatg gaaactaccg attttagaag gggtatacaa
      901 acaaatatta gtatcggagt agagaaggtt gaacccaacc agtaaataag taaagacaat
      961 tttgtgctgc gttgagaagt gaaaaataaa cctttgtagt aatactagtt aataaaaaat
     1021 atacaaaaac actgcgaaaa tcattcttga gtttcgcagt gttttttgcc taatgactca
     1081 agtttattgg gtaatacttt gattttcttt ctacaaataa tcagcgatca gttgtaattt
     1141 tttctctagt tttaatggct ctttgtcaat aaggagaaaa acaagtcggg tcttttgtct
     1201 cggaaagctt caaccaactc gtgaataaag gttacgcctc cttgaaaggc gtggaaaaac
     1261 caagtaatcg atcaatcacc aatttcgcat ttggtagaac atgtttggtg agctgaaagt
     1321 aggtggcgtt catgtctgta actaagaatt ctatttcttt aggattagtg cagctaagga
     1381 aatagtttgt taatcgagga attttttgtg taggtaaatt ttctcgatta atttttctgt
     1441 ctcgccatcc gcggaaataa aactcagttt atcctcaacg gaaacgtgag aacgaaattc
     1501 acaaccctca acactcaaga cagaattctt ttggaagact ttggtaaata gcttctcaac
     1561 tctttcaatg tgcgaataac ggttgtcaaa gatacctaac aacttttcga aataaaaaat
     1621 aacgacactt tttcagtcag taaagaagtg attttatgtc tgacatgatt tgaaatcgag
     1681 tgccttggac ggataaaata actttgagcg ttccaatggc ttcgacagtt tttacaggta
     1741 tagcgctgct tttttaggcg tataaccatt ggcatatgat tatattattc aaagtggaca
     1801 atggtttcct tcttcttgtt tttcaccacc attaatttcc tatttccatc taccacagca
     1861 gaaccacaat ttctacagac acatggagca gggaagagaa ctgcagcaac gatcaatgtt
     1921 tttttcttct gtaaggtttc gtaagagacc tctgtaatca tcaaattttt gtctattgat
     1981 ctcagaattt ttttgataga accattcata aagcatatcg ttctctcagt tgtttatttt
     2041 gtggtgattt aatcatacaa gaaaacgata tgttttttta taaaaacatg aataggaaaa
     2101 atagttgaca agaaaatgac aacgccatat gatgttccat agtatttaca acctgtcata
     2161 gatgactgta aaaaataaaa gtaaaaagaa aggacgacaa caggtggatt tttatcagtc
     2221 tctacaacta gatccgttta ttttaaaaca aaaaatacga gaagcagctt ctaaaaaaga
     2281 aaagtgcatg tatatttgtt cattgttttt acgatcatta ttcatcgtat tgtttgccat
     2341 ttgttttatc attataatta caacattatt tgaatcgaag cataaaccat acgctgtggt
     2401 tttattctgt atgttgatga gtattcgttt tgttgacttt ggttataaga tttcccattc
     2461 gatcataggt ttagcaatcg tcatgttctc actattagta gcaccgtatg tccagctgat
     2521 caaatggtca gttatgggca tgttgattca ttttatttta ctaagcagca tattaatggc
     2581 aaccgctagt gatcccaaaa tggggaatgc ttctttgtac ggcttttcat atctctttat
     2641 tgtttattcg ttacctaaag attcgttgaa caagaatttc tttacacaaa caagtagctt
     2701 attatttttg tttttttgtt ggttttcagt tctcctttac agaaaacatc gagaaaagaa
     2761 caaagacaaa agcttgttta aagagatttt tttgaaaggc atgtattcgc aggaaaaaat
     2821 ttggatgctc atctatgcat ttggcattag tcttttgatc gttgcaggag agtatgtccc
     2881 ttttcagcga ttgatgtggg cagggtttgc attttcttct attgtatcta gctatggatt
     2941 gatgtcgatt ggtttcaaag aacgagcagt agaccgaatc attggctcat tgattggatg
     3001 tgttttattt attggtatca gccaatttat tccttttaac tgggtcggta tattaggtgg
     3061 tctagcttta ggtgtttgtt ctacctatag atataaaaca gtttttaatt cttttggtgc
     3121 tttggcaatc actgccagtt tattcggggt tccaggagca gtaacgatcc gcatttttga
     3181 gaatatcctt ggggtatgtt taggaatcat gtatattggg gtgactgaaa tacttatccg
     3241 aaaaataaga gaaaaacacg gtttgaatca ttagatgaga tcgaataaaa aataaggaaa
     3301 aagtgaagat acacatggat gataaattgc tatcattcca tgtgtatctt tttacggtaa
     3361 atcagtgaaa cgttcgactt tcatttttaa tttatacttt ttacggagtt cgtttatttg
     3421 agccatcatt tcggatttgt gatgcttttc gattgcttct tcatctttcc aacggtcgat
     3481 cagtaaaaga gattctggat cttctagtgg aaagtaatag tcatatttct cgtttccttc
     3541 ttctgcacga atcgctttga caatgtttct ttcgaccatt tcttctgcaa attttctggc
     3601 ttgtccattt gtacttgtat acaaaatatt cactgtgata ctcactaaat cccctcctga
     3661 aaaaattcta tcactagtat atcacggtgc cagaaattat tattcaagat atgatacaca
     3721 ttttttccgc aatgctacgg aaatatatat tttgaataga aaacgcttac aagatatgct
     3781 tggtttataa aaataaaagg agtgattgat ttatgaaaaa agcattgatt atttgtgcgg
     3841 caggaatgtc atcctcgatg atggcctcaa agacaacgga tttctttaag caaaaaagag
     3901 aagaggtact cgtagatgca gtttcagcta cagaaggcga taatatgatt aagaatagtg
     3961 attttgattt atttctgatc agcccgcaaa cgacgatgtt tttggataaa ttcaaaaaat
     4021 taggagaatc tgttggaaag cctgttgtta gtatcccttt ccaagcgtat gtcccaatcc
     4081 ctacaggcat ccagaagtta gcagaggtga tcgaagagaa catatgatgg aataggagtg
     4141 gatgataatg aaacagaagg aaaaattgct gttgagatat ttgattgatc acaagaagga
     4201 gtatgtcacc agtcaacgtt tagcttctga attgttatta tctgatcgga caatccgtaa
     4261 ttacttgcag cggatcaaag agttagtaga aaaaaacgga ggtaagatca ttgctaaacc
     4321 aggttatggc taccaactgc atattttaca aagactgaca tttgacttgt ttttgagtcg
     4381 gcaagaaata gtacctggat atgctagaga accgcaagga ttttatgagt ccgaagatcg
     4441 acaaaagtat atattgaacc aattgctttt ggaagatgcc attcttttta tggatgattt
     4501 ggcagaagag ctttatatca gtcgttccag tttgacaaag gacatgcaag aaatcaagga
     4561 gcgattgatt ccatattcac taaaaatcgt ttctaagcat ggtcaaggga catggatcga
     4621 aggggaagaa agaaatcgac ggcattttat catggatact ttttttggaa accattatgg
     4681 aaattcattg aaagaatatt tagggcaaag ccgttttttc ccagacatca gttttgaaga
     4741 gctagtcatt atcattctcg atgaaacaag agaagctaag ttaaaagttt cggattttat
     4801 catacagaat ctgactttac acttggcttt ggggatcaaa cggctccgag aagggtttga
     4861 aatcaaggaa ttaggcatcg aacaagaagt ttctaagcga gtagagtatc aagtggcgca
     4921 gcggatcgtt caacgtattg aggtaatcgc aggtgtatcg tttcccgaag aagaaattgc
     4981 ttatttgaca ttacatctca tggctaagtc gaatcacaaa gaaaatcaaa atgatcagga
     5041 actatcaaag gaattagcga aagttctgaa aagattgtct caggaatttc atttttcatt
     5101 agtagaggat ctccagcttt tcaatggact actcgatcat ttgtcaccga tgatgattcg
     5161 attgagccga ggtattcgca ttgagaaccc attgactgag gagataaaga aagaaaatcc
     5221 caaagtcttt gacgcagtaa aaaggcattt cagcaacatg ccggctttga aaaactatac
     5281 catcaatgaa gatgaatggg cctatttggc tttgcatctc atggcggcat tggaaaaaga
     5341 aagagctgcg cataaactac atgcattgat tatctgtgca acgggttacg gcagtgccca
     5401 actattaaag aatcgcgtag tcagtgaatt cggtaaaaat attacagtgg taagtgtaaa
     5461 aggctattat gagatcaatg aaacaacttt aaaaggaatc gacctgatta tttcttctat
     5521 tgatctttcg acaatgtttt tcaaaattcc agttttacat gtcagtattt ttttgaatga
     5581 agatgatgtt cgtaaaatac gaaaggtagt tggagaatct ataccctatc attcctcaga
     5641 tagaccgata ccagcatttt ctctacagca aaaaaagcag atttacaccg aacagttgtc
     5701 tgaaaaattt ttcaagactt atacgtacga accgaaaaag gaagaaattc ttcatgattt
     5761 gctgcaaaag ctgagcataa atgaagaaga aggatatata agagaaatgc gaaagcagat
     5821 ccagcaacgt gaaaatatgg gacaaatcat attcagtgat acagtggcag tcccacatcc
     5881 cgctgttcca gttggaatcg aaacaaaggt agccgttgca ttgattcctt ctgggatgca
     5941 gtgggatcaa tatcaagaaa ttcattttgt ttttttagtt tcgccttctt atgtcgaaaa
     6001 tgaaggaatt acggtcgtga ctaaagcaat cgttaggtta gttgaccagc taaaagtaca
     6061 gcaggaaatc ttagctgaac ctatttttga gaatttcagc agtaaattta tcaaactgat
     6121 cgaataagga ggaaaacaga tggctgaaaa aataaacagt gaaacactac aagtgacttc
     6181 ttttgatatc attttccata gcggaaatgc acggacactg atacatgaag catttcgctc
     6241 gatgcgtaaa gagatgtttg aagaagtaga agagaagttg cgacaagcaa atgaagagat
     6301 tcttcatgcg catcagtcac aaactcaact tctgaaagaa tatgccagcg ggacaaaaat
     6361 agaaatggaa attatcatgg tccatgcaca agatcatctg atgacgacga tgacattatt
     6421 ggaagttgca caggaaatga attatttgta tcaaaaaaat aaatagaaag gaaggatcat
     6481 tgtgcaggat acagtaaaaa ggaaaatcga attagaaaaa aagcaactta gtttgaaaaa
     6541 catgtatttc aatcgttatc taatcgtacg ttacctgact gcctttttct ttttcatgaa
     6601 catgcaatgg atgattctgc ttctatcagc taaaagttta ggaagtagtt taccgatgat
     6661 tctgatttta gctattttgc ctgcagtagg agaacaagta aagctttatc gaaaacacca
     6721 aacgaacgtt ccatggacaa agtggtattt tttgttccag agtgtcttta atttattagt
     6781 gattccagtg ttgtttacct caggatttac attcttgtat ccttttatgg caaataacaa
     6841 tggaggacag ttatttgttt tcattcttgt tgtaagcggt atttttgcca gtgcatttat
     6901 acagtatcgt ttaaagaaaa tttcactcaa ccaagaccaa cagtatatcc gtattaaaca
     6961 atatgaaaaa gcgttatatt taggaaagga gaataactaa tgtttgattt tttgcagaaa
     7021 tacctgatgg gacctatggg gaaaattgcg caacttaaaa tcgttcgggc tgtcatggca
     7081 gcggggatgg cttctattcc tttcacgatt gtaggctcga tgtttttggt tttaaatatt
     7141 ttgccattac cgttcccatt tttagaagga ttttttaatg caactttttt caaagttagt
     7201 gacttgtaca tgatcgtcaa tacaatgacg atggggattt tatctattta ctttgccatt
     7261 gtgtttgctt atgaattaac gtcaattgaa cgagatgaac aaaaattaaa tgttaatccg
     7321 ctcacggggg cattactatc tgtttttgca ttctttatgt gtatccctga attgatcatg
     7381 actgatggta aaatcagctt gattgcttct atcaatgaga cagaaactgt agtaaatggt
     7441 attaggatgg gctcttttgt cgaacgttta ggaacttcag gaatctttac agctattatt
     7501 atgtcgatta ttgcggtcga attgtattgt atgtgtgtca agagaaattg ggtcataaaa
     7561 atgccagatg ttgttccgcc aggagtttct cgttctttca ctgctctgat cccaacattt
     7621 gtcattgcgt ttgtggtgat gatcatcaat ggattattag ttgcactagg aacggatatc
     7681 ttcaaaatga ttgctatccc atttgggttt gttacgcagt tgacgaatac atggcttggt
     7741 gtcatggtga tttatttctt gatccatgca ttgtggatcg tagggatcca tggagcgaat
     7801 atcatcactt ctttcttgac cccgatcgta ttagctaata tggcagctaa cgcacaaggc
     7861 gcaaattatc cgttggcagg agaattcaac aattcttatg taaccgttgg tggatcaggt
     7921 gcgactttag gattgatcat ctttattgca ttcctcgcga aatctgatca gctgaaagtg
     7981 ttaggaaaag cctcacttgt accaggatta ttcaatatca atgaaccaat cattttcggg
     8041 atgccaatcg tctacaatcc ctatttagcg gttccgtttt tcttagctcc gatggcttct
     8101 gctacactcg cttattttgc cattcggctg gaaatcgtca aaccgatgct tgcacagatg
     8161 ccgtggcctt caccagtcgg gatcggagca tttgttggta gtggtggtga ttggaaagct
     8221 gctgtgttag cagtcatttg tgcaatcatc gcattcatta tctggttccc atttatcaaa
     8281 ttctatgata ataaattatt aaatgaagaa agagaaaagg cagcagaatt agctagtgaa
     8341 aagttaaaat gatttctaag aaaaaaggaa ctgtgacaaa aaatcacagt cccttttttt
     8401 cttagaaatg ggaaaccact agtatataaa taccattatt cttcaatcaa ccgcttcacg
     8461 attgcataat ccccttcata aggttcatct acaccattga ttttttgata gggatccacg
     8521 ccttttcccg caataacgac tgaatcttgc ggagcgcttt ctgctaaagc gcgtcgaatc
     8581 gcttcaggac gatccatttc ataatgaacg atcaaatctg gattagtaat tgcttcattg
     8641 atttcttccg cgattttttt cggatcttca aatgctgggt catctgccgt caaaaaggcg
     8701 atgtcagctg tttctgatag cacttttcca aaatcatgtc gacgggagat tgctttgttt
     8761 cctgggctgc ctaatacaac aattacacgg ccatctggat gttcattttt ggcaaatttc
     8821 agcaatgttt tcaagcttag ataattatgt gcatagtcca catagacatg cgctccattg
     8881 gattggatca attgatccat tcggcctggt acacgagctt cttttaatcc gtcttgtgca
     8941 tcttgactgg aggcacctgt tagtgctgcg gcaatgatcg cactggctgc attttcttgg
     9001 ttgaatcctc cagccagcaa aatatcataa gcagtatcgc agatagctaa gcgatcttca
     9061 tgagaagata aagtaaaacc gtgagtacct ttatctgaac ggatcacttg ataattgctt
     9121 tcttccgaac gaccataagt gatcgttgga atctggaata gatcggctgt ttccctaagt
     9181 aaatcaaaat agtcactttc atgatttaaa acaactgttt ttgaattcaa gatcaattgt
     9241 cgcttgcaat agaaatagtc atcaaatgtc ggatgttcga tcggactgat atggtcaggc
     9301 gagatattca agaagattcc gacatctaaa gtcaagccgt atacgcgttg tgttttgtaa
     9361 gcttgtgaag aaacttccat cactagatga gtcataccat tttcaactgc ttctgacatc
     9421 atacgatata aatctaatga ctcaggcgtt gtcaaatggg atttgaaata tgttttgcca
     9481 tctaacgttg tattcatagt agaaagcaat gctgtttttt tatttgttgt gtgatccaag
     9541 attgcttttg taaagtacgc agcagttgtt ttaccttttg ttccagtgaa tccgatcact
     9601 ttcaatttat tttgcggata gtcgtaaaaa gccatagcaa gaagcgccat tgctttacgg
     9661 atatccgtta cgatgattcc tactgctgaa ttttcgtatg gttgttctga tacataatat
     9721 tgaataccct gttcgattgc tgaatccaaa tattcttctt tgaaattcat tcctttacag
     9781 aaaaacaaag tagaagcatc agcttttctt gaatcataac ttaactgaag aaattcagct
     9841 ttttctggta catcaagatg ccagcctctt gttgaaacaa attcttttaa tagattttct
     9901 tttaatagta aatgacggat gtcttctaaa gagaagctca ttgattgatc cctcgcttta
     9961 ttcaatttct tggtttatta tagcacactc tttttaatat atcgtttgtt tccgctatga
    10021 caaaatccag ctttattcaa attttcttga cacaggggac aagcggatga gtattttcat
    10081 aaacaatgaa ctgactgtaa tagataggag aacgaatagt gtctccaaca atccaaaaac
    10141 ataataattc aaaaagacga taagactatt ggtaagtaaa agtccttgcg gcattggaag
    10201 ccgaaaaaat ttgtggaaaa taatcggcgg tatcgttata ccgccatttg aggccccgac
    10261 tgtgtacaat gtgtaaaccc caagactgaa caaaagactt cctgaaatca gtgaaaagaa
    10321 atgtgaggag atcatttcca cttttggaac aatctctaaa acaacaggaa aaagcagact
    10381 tcccgctaca gtcttaaaaa atactgattt tcctaatagg acagcggcta gaagcagcat
    10441 cataagattg atgctccaaa cagtaactga gcgttggata gaaaaggccg tttcaactaa
    10501 atgtccgatg gcgcccactc cggcggaagc tatatcgtga gggagcaaga accaattcaa
    10561 tccaactgtg ataaagaaaa gacctaaaaa tataacgggt agttttttta tttcttgtgt
    10621 cattgatatc tcctataaat gttagccata aaaggctgta tatttcttta ctttaccaaa
    10681 aaaacgaaac cgaattcaaa aaaacaattg ttcttataaa agttatataa aatcgattgc
    10741 cagtttctgt tttaccaatt aaaatgatag taatgttttg tagaaagttg gaatctgacc
    10801 gatggataat caaagaaaac cagcattaga tcaattaaca ccgcaagaaa aaatggcacg
    10861 aggctctgct tggatgaccg ccagtaatat catttcaaga ttgctaggcg ctgtctatat
    10921 cattccctgg tatgcttgga tgggcgaaaa tgctaaggct gccaatggat tattcaatat
    10981 gggatacaat atatatgcat tgtttctact gatctctaca gcaggaatac ctgctgcgat
    11041 tgcaaaacaa actgcacgct ataattcatt gaatgaatat ggcacttcac gacgattatt
    11101 tatccgtgca ttacagatga tgggcgggtt aggcctgttg tttgctttgt tcatgtacat
    11161 cgcctctcct tggctagctc atgcttctgg tggcggagaa gaactgattc caacgatgcg
    11221 ttctttgagt atcgctgtat tggtttttcc ttgtatgagt gtgatacgag ggtatttgca
    11281 aggcaatcaa gaaatgatgc cttatgcgct gtcgcagatt gtagaacagg tggcacgtat
    11341 tttttatatg ctattggcta cattcatcat catgaaagtc atggatggtg actatgtgac
    11401 ggcggtcacg caatcaactt tcgcggcatt tatcggtatg ctagcaagta ttcttgtcct
    11461 tttgtatttt ttgaagaaac atcaagcgta tacatcggcg tttattcact acagcgaaaa
    11521 caaaataaat attgcaacga aggaattgtt gttagatacc gttaaagaag cgattccgtt
    11581 tattattgtg ggttcagggg taacgatctt caaattagtc gatcagttca cttttatgaa
    11641 gatcatgtct gcatccaccg agtattccaa tgcacagtta ctggatcttt tttcgatttt
    11701 tagtgccaat ccagataagt tgacgatggt agttattgca ttggcaacat cgatcgcgtc
    11761 tactgggtta ccgttgatta cagaagctgt tacgttgaaa gatcgagtag gtctggcaaa
    11821 attgacaagc ggaaatttac agttgttttc attttttatg tttccggcga catttggtgt
    11881 tatgttactt gcctatccgc taaatacatt attttataca ccggattctc taggaagtaa
    11941 tgtactgatc caagcaagtt ttgtaggact cttcctagga ctatatatgc tagtttccaa
    12001 catgctgcaa ggaatgtttg aaaacaaggc ggcaattaat tatttggtta ttgggtttct
    12061 agtgaaactc cttcttcaat acccagccat tcgtttattt gaagtatacg gccctttatt
    12121 ggcgacaatg atcggatttg ctgtgtcttg taccttgatc ttaaagagaa tccatgaagt
    12181 agcccgcttt aaaccaagtt ttgtctggcg caggacattg ctgatcttta ttcttacctt
    12241 gattatgctt ttggcttcgt ggatcacaaa gatgattttt ggtgcttttt taaacgaaga
    12301 tagcaaattc cagtctctat tgttgattct tgtagtagca ggtatagggg ctttagtgta
    12361 tggttattta gctttgaaaa tccgcttggc agaaagacta ctaggaccag gaatagcgcg
    12421 tttacgacat aaattaaaaa taaaataagt gaatcagaag agctagattg atgctctttt
    12481 gaaatggggg aaacgcatgc gtttagataa gtttttagca gatatgggac ttggcagccg
    12541 caaagaagtc aaaggattaa tcaaaaaagg aacgatcgaa gtcaatggac aagtggtgaa
    12601 aagcgataaa gcgcaagtaa atgaattcga agatgcggtt acttatttag gagaaatcat
    12661 tacgtatcaa aaagattttt actacatttt gcataaacct gcaggagtca tttctgctac
    12721 tcaggataat catgatcaaa ccgtaatcga tttattggaa gaccaggatt atcgggaaga
    12781 tctttttcca gtcggccgat tagataaaga cacagagggc ctcttgattt taacgaatga
    12841 cggggtgttt gcccatcagt tactatcacc taaaaaacat gtggagaaag aatatctagc
    12901 tgaggttagc ggtataatga cagaagaaga tatccgttta tttgcagaag gactgattat
    12961 tgatggcgat gagcagacat tgccggcaaa actccaaatt gatcaagtag atcaagagac
    13021 agaaacttca attatccgtc tgattttgca tgaaggaaag tttcaccaag ttaagcgaat
    13081 ggtcaaagca gtaggaaaag aagtcttata tttaaaaaga atccgtatgg gaaaattttg
    13141 gctgcctaaa gatttgaata aagggcaata tcgacccatg accaaagaag agctagaaca
    13201 agtgagagaa aaataattga atggatagct aaaagaataa gcagagtagt tgtagcgcca
    13261 tctgaaaagc agacttgtcc gtctgacttt cggatggctt ttttgtgaaa tttcggctta
    13321 tttccgtaga agctacttct ggaacaccgt ttgttcggaa taagggactg tgacaagact
    13381 tttgttacag tccccattgt tccttgtgac tcagagttag atagtaagga cacgatctcc
    13441 ctaatactca ggccaaaacg ctgaattcac aacctctgat aaacggtgtt caatcagctg
    13501 accctcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttccc gtttttttct
    13561 ctaatactca ggccaaaacg ctgatttcac aacctctcct atactttgtt tcattttccc
    13621 tatactttgt ttatttattc tcattattga aagcgctata attacgttgc gaatgaatcg
    13681 aaaggggttt ttagatgaaa aaacgaaagg ggttcaatca tttttttatg aatctatggc
    13741 gttataaagc acttgtcctg atggctgtac cgggtatgct ttggatgatt tttttctttt
    13801 acatacctgt aatggcgaat gtcgtagcat tcaaaaattt tcatatttca gcagatgggt
    13861 tcttggctag cttgagggaa agtccttggg tgggttggga aaatttcaaa tttttatttt
    13921 cttcggatca agcatttctc atcactaaaa atacaatttt atataatgta gcatttatcc
    13981 ttttgaatct gctgatctca gtcgtatttg caatcattat gagcgagttg agaaataaac
    14041 gactcgttaa agtttatcaa acgatgtcct tactacctta ttttctatct tgggtcatta
    14101 tcagttactt tgtttacgct tttttaagtc ctgacaaagg aatattcaat cagtggatca
    14161 ctggacatgg aggagaagct gtcaattggt ataatgaacc gaaatattgg ccgtttatct
    14221 tggtgttcat tggtacatgg aaagggattg gttataacag cattatttac tttgcatctg
    14281 ttatgggaat cgatccgact tattatgaag ctgctatggt tgatggagct agcaaatggc
    14341 agcagatcaa acatgtgacg ataccacaac ttattccact aatgacgatt ttaacgattt
    14401 tagccgtagg aaacattttc cgagctgatt ttggcctgtt ttataacatt cctaggaatt
    14461 ccggtgcatt atatgatgtg actcaagttt tggatacgta tatctacaat ggcctgacat
    14521 ccacaggaga ttttggtatg acggctgctg caggacttta ccaatcagtt gtcggctttg
    14581 tcttgttgat gatcacaaat acgatcgccc gacgttttga tagcgattct gcattattct
    14641 aaggaggaaa aaaatgaaaa aaaagaaagt ggagagagtc caagtccgct ctttcaataa
    14701 gacggctaat tttttctcta atataatgat tgcactcttt gctatttcct gtattttgcc
    14761 atttatattt gttatcgcca tctcttttac cgatgagtcc atattgtcga ctcacgggta
    14821 cagtttttgg ccagaaaagt tcagtatatt tggttatacg tacttgttcg accagatgca
    14881 ggataaaatt ttccaagcgc ttttcgtcac tgtacttgtt actgttttag gtacactgat
    14941 caatagcacg gctacttctt tatatgctta tgcgatttca cggtcaaact ttccattccg
    15001 tcgttttttt accgtttttt gtttgattac gatgttgttc tcaccaggga tggtggccaa
    15061 ttatcttgtt atgacaaatc ttcttcagtt aaaagatacg atttgggcat tgatcttgcc
    15121 aatggctgtc agtcccttca atattattgt gatgcgcaca ttctttaaac gttcggtctc
    15181 tgattcgatt attgaatcgg cacggatcga tggagctagc gaactgcgaa tatttgttca
    15241 gatcgtttta ccgttagctg ttccaggtat tgcgacaatc agtttatttg ccgcattggg
    15301 ttactggaat gactggttca atgctttact atacatccaa gatgataagc tagttccact
    15361 acagtatctt ttgatgaaaa tccaaagtaa tattcaatat ctgacacaaa attcaggagc
    15421 aggaagccaa ttgacaggcg gattagcctc agttccagga gaatctgcca gaatggcgat
    15481 cgtagtcatc tcgacgttgc ctattgcgat cagctatcca tttttccaga agcattttgt
    15541 caaaggtcta acaatcggcg gagtaaaaga ataaagaaac aaaaatataa atcataaaat
    15601 taggaggaag aaaaatgaag ttatggaaga aactagcctt tacaggtgtt tcagcgttgt
    15661 tgttgggaac attagcagca tgcggaggtt ctggttctaa agaccaggca gaagctagca
    15721 attcggacac tttgcagatg tatcaaatcg gagataaacc agataatttc gatcaattga
    15781 tggaagtagc aaacaaacga atcgaaaaag agatcggtgt aaaagtcaat atcaattaca
    15841 ttggctgggg cgattacgaa aagaaaatga acgtcatcat ttcttccggg gaaaattatg
    15901 atatcgcctt tgcgaacaac tatgtttcca atgcccaaaa aggagccttt gctgatttga
    15961 ctgaattagc gcctaagtac gctgaaaaag cttataatga tttagatgaa gcatatatta
    16021 aaggaaatct ggtcaatgga aaattatatg ctttcccagt caatggaaat gtctttgctc
    16081 aacaagtact tacttttaac aaagctttac tagataaata cgatctttca attgatggaa
    16141 tccaatctta cgctgatgca gaaaaagtct tgaaggaatt ccatgaaaaa gaaccaaaca
    16201 cggcagcttt tgccattgga caaggcttca aagtccaagg gaactttgat tatcctttag
    16261 ggaatacgtt accatttgct attgatctgg atggagatga ttcgaaaatc atcaaccaat
    16321 acgataatga aacgtatatc ggactgttac gtacaatgca tagctggtac aaacaaggac
    16381 tcattccaag tgacgctgca acgagcaata aggattatcc actagaagga aatacttggc
    16441 taatgcgtgg agaaacacaa ggaccgtatg attatggcga tacaattttg acaaatgcag
    16501 caaaacaaga acttgtctca aaagcaatta ctgttccact aaaatctaca gctcaagcac
    16561 aaatggcaaa ttttgtcgta tcaaatactt caaaaaataa agaaaaatca gtagaacttc
    16621 tagggctgct taacagtgat ccagaattat tgaatgggct tgtttggggg atcgagggag
    16681 aagcatggga aaaagtcgat ggttcagatg ataaaatcaa attgctagat ggttatcagc
    16741 caaatacaca tatgtctgct tggaatacag gaaacaacaa gattctatat acacaagagt
    16801 ctattacgga tgacatgatt gccaaacgtg atcaatcgat tgctgatgca gaaacttcac
    16861 cgattttagg attcagcttc aacactgaca gtgtcaaaac agaattaagt aatatttcta
    16921 atgtcatgaa tcaatattta gatggattga atacagggac tgttgatcca gatgaaacat
    16981 taccgaaatt gaaagacgct ttggacaagg ctggctatga taaggtattg aaagaaatgc
    17041 aaaaacaata tgatgagttc cgacaagaat aataatgaat aaagacaaag gggttgtgac
    17101 aaaagacgtg tcacaacctc ttgttccgaa taaacggtgt tcaaaagcca gtttctcggt
    17161 attaagctaa atatatgtaa aaatgtggaa agccatattc acaaaatttt tcttactact
    17221 cgaaactaag cggctatttc acaaactctt ggtaaacggt gttcaatcag ctaaccctcg
    17281 gtattcgctc acaaaacgac aaaatatgag gaactatttt tccgtttgtt tctctaataa
    17341 tcaggtcaag gtgctgattg cccaaccttt ttttgtataa tgagaaagta taaacttaat
    17401 gtttggagga gaagatatgt tagggaaggt tttggaagag ttatttatcc ggatctgggt
    17461 cattataaaa ctaaccttgt atttctggat atatacattt gccggcggga tcatctttgg
    17521 attaggtgcg gcatggaaaa cagtcaatga actattttat ttgtacggat tcgagtataa
    17581 agaaatcaca ataaaaagag gctggaatat atataaaaga aattttttaa gaggcaatct
    17641 gctatttagt ttatttttat ctggtactgc tttattgagt tacaatttat atttatctgt
    17701 tcaaatcaaa gggctcattt ttttagctat tgattttatt ttactttttg ccttgctctg
    17761 cctatttgct acttatcaat acagtatgat tttagatagt gaatatacga tctctgttcc
    17821 taatctgcta aagctaagtt ttatttcggt tttttccagc ttttcgtctt ttctaaaaat
    17881 aattattggt agcggtataa ttttaggcgt gacttggcaa ttcaaaggat tgatcctgtt
    17941 tggtgtcatt ggtcttttga cggtttggaa tggtacgatg acaacacatt ggcgtgaaga
    18001 attagataaa cagttggaaa gttatgaata agtttcggat tctattttca aaaggaacct
    18061 tactaaatcg tctgttgcgg aaatacgcgg ttatcatgat cggtgtaacg atgactgcta
    18121 ccgttatttt tagtatccat acttgggaac aaaatcaaaa acaggcagaa aacatgacaa
    18181 gtgatgccgt tcaaagcaca agcagaatgc tgaatgataa aacaaccttg agtaggatca
    18241 tcaaaaacca gcttgtaggg aattccgaaa agatcgaaaa tgtgacgacc tacttaacaa
    18301 aacccataga tcagtatctg atgtatgtat acgaacagca aaacagtacc gatgaattag
    18361 tttctttccc aaatcaaatc aaagatctct acgcaaatta tgaagaacta agtgcgatat
    18421 atatcgtgtt gaatcaacta ccggagtatt atgaatcttc tagagaaaac aaaggtgggg
    18481 aaataaaaaa ggggacacca aaattactag acgcctttta tatcaagttg cctatcacac
    18541 aaggaggagc tgagtcagga agtattttta ttggttttca aaagaaagaa ctagatatga
    18601 ttttagaaaa tctaacgtca ttcaatggac tctctttata catgatttct ggaacgacaa
    18661 atcgactata cacattccat gataataaaa tagctaaaga aacgtttgaa agacaagaaa
    18721 tgatcatcac agagagtctg aagaaaaatt cacaattgcc gattgacgat ctggaaaaaa
    18781 acaattttgt tcaacaccaa gaactgtctg atgattatcg tatattagct gtactagata
    18841 aaaaaagtgt aaaaatcgaa acgggaaaaa atcttgcccc gctgatcatt ggtatcatta
    18901 ttttagacaa tatactgctt atctttcttt ataaaacatt caaacgatat tcacagcaag
    18961 tatctatcgt catgcaggcc atggatcaaa cagcagcagg gaatttagag acgcggatcg
    19021 acataacaaa cacggaatat gaactgaggg aactttcaat cggtatcaac gaaatgttgg
    19081 atagcatcaa tcagtttgta gaagacatct acaaattaga aatcaaacag caagacgcac
    19141 atatgcgggc gcttcaagca cagatcaatc cacacttttt atataataca ttagaatata
    19201 tccgaatgta tgcaatcagc gaaggaagtg aagaattagc agatgttgtg tatgcgtttt
    19261 ccgctttgct tcgaaacaat acgaatcaag agaaaacgat cactttaaaa gaagaactgg
    19321 acttttgcga aaaatatgtc tatttgtatc aaatgcgtta tcctaatcga gtagcctatc
    19381 attttatgat cgatcctgat ttggaaaaga tcgaagtacc taaatttgtg atccagccat
    19441 tagttgaaaa ttattttaaa cacggtattg attttactcg attcgataat gcgctaagtg
    19501 tcaaagtctt gcaggaaggc aaacgggtaa ggatcatcat caaagataat ggaaaaggga
    19561 tgactgaaaa acggctaaaa cagattgaag aaaaactgtc tcatcctaaa gtggaacttc
    19621 acggttctat cggtctgcaa aacgtgaatg aacgtttacg tgccagcttc ggcagcagtt
    19681 attatatgtc gcttgagaat aatgagacag gtggactgac cgtttctatt acattcaagg
    19741 agggatgagc gtgtatcaag tgttattggt agatgatgaa tacatgattt tgaatgggtt
    19801 aaaaaagata attgattggc aaagtttagg ctttcaaata gtagcaacag cagagaatgc
    19861 caaagaagga ctagctgtac ttgaacagcg acagattgat ttagtagtaa cggatgtgac
    19921 aatgccagaa ataaatggac tggaatttat tgaagcggct caaaaagaac gtcataattt
    19981 tgaatttatg attttatcag gataccaaga attcgattat ttgaaaggag gtatgcaatt
    20041 aggcgccgtg aattatttga tgaaacccgt gaataagttc gaattggttg aaagcctcaa
    20101 gaaaatcaaa acacggttag atcagcaaaa tgaacaaaaa aatcaacaag aaatctatca
    20161 agaactgtta ttcagtcaat ggttgaatga agaattggat gaaataagtg aagaagaaat
    20221 aataggacaa ataagtgaga agcagcatag gatagtattg attcaactgg caagaactca
    20281 tgatactctt atcaatagat ggttgcaaga acggcaacaa atcttttact atcaacgaaa
    20341 ttacggagac cgtgtattga tcacgttgtt gttggaggca gatgaagttg atggcttctg
    20401 ttgttttgtt caagaaaact ttcctgatca ggaatggctg atcagtatcg gggaagagac
    20461 agattctttg gacaaaatcc ctgaaacatt ccaacaagcg aaagacaatc tacagttgca
    20521 tcaattttat ggagataaag acgagcatgt tttttacgca gtacaagcag aaacaaaaga
    20581 tcaaaccatc gatttttcaa gtttcagacg cgtgctgcaa aataaacaat tggaagtcgc
    20641 tcaaaaaatg atcactgatt tttttgaaca gtttcagtta gcagccatga tgccggaaga
    20701 tatacgatat tccagttttt tactgtttat ggagattcaa cgggaattga ttgatctgga
    20761 agatgaggaa tatttacaag gaatcgaaaa aatccatcag gcaaaaacgg tgcaagaact
    20821 tcagcagcta cttctgtcat tcatcaaaaa gcatcagaga cagaaaaagt acagtgacaa
    20881 tgtggaaaaa gtaatcgtaa tcctgcacca gcattatcaa gaaccactta cactcaaaga
    20941 agtgtcagaa aacctgcatt taaatgtcat gtatctagga cagctgttca aaaaagaaac
    21001 gaaaaaaagt ttttcagctt atttgaacca tttacgtatg gaaaaagcga aacaactgct
    21061 tttgcacagt aatcaaaaca tcaatgagat agcaagtgag attggctaca acaacaccac
    21121 gtatttctct aaattattca agaaaatcgt cggcagatcc cctaaagagt accgagaaaa
    21181 cagtggagaa tcataaaaga aaaagccaat gtaatgaaat aacttataaa aaattgtcta
    21241 gaaatctaat tttgggctgt tcttattact tgaggcaagg cagctttttc atgacctctc
    21301 gataaacgga gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtgg
    21361 aaagccattt tcacaaaatt tttcttaata ctcgaaacta aacagctttt tcacgacctc
    21421 tccactaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaat ggcaaaatat
    21481 gaggaactat tttgccattt gtctctctaa tactcaggtc agaacgctga tttcacaacc
    21541 tctcaataaa cggtgttcaa aagcttgcat ctgcggtaat aagaccaacc aaacgaaaaa
    21601 tatgaggatc tatttttgct tggctgttct tattacttga tgcaggacag ctttttcaca
    21661 acctcttgtt aattatagtt tgataaggaa aaaggcaaat cttttgcttg atatttctta
    21721 gggtgaggga tgatccctaa ttggtaagag atcgtgccgc ctttcagcaa atcttgatgg
    21781 gtaaaatata atttcgtata ttctctgtcc atccgtttga ttttatggat aaattgttgc
    21841 tgcggccgat taggcgttgc ttcaatcgtc aattcctttc catttgacaa aagcaaaaca
    21901 gccttgtcaa ttaatggcat accgataaca tattcaccgg ttccaggcgt gacaggataa
    21961 aatcccagac tattgaagat ataccaagcg gccatacttc cattgtcctc atctccaggg
    22021 taacccattg gagaatcgtc gaaggtctga gtcatcaact gtttaagcag tggctgtgcc
    22081 atttcaggtt gtcctatata actgaacaag taaggatagt gaaaacttgg ctggtttgaa
    22141 atagctaatt gtccaaattc tatcgcggcc atctcactca tttcgtggat ctcaaaacca
    22201 tatcctcctg ggtcaaacgt tgggggctga ttgcacagct caatgagttt ttctttatat
    22261 ctctcactgc caccatattt tccgatcagt cctgaaaaat cgtgataaac agcaaagctg
    22321 ctttgccaag cacttccttc tgcataatct tgtccccaac gattagctga aaatggttct
    22381 ctgaacttgc catctttatc ttttgaacgc ataaatcctg actcatagtc aaagatattt
    22441 tgatagttca atgattgctg ctgatatttc ttcgtcattt cctcttcttc tagtaccttg
    22501 gcaacttggc taatacaaaa atcgctataa gcatagtcta atgtgtgatt gactgattcg
    22561 tggtagtgat taggaacata gccatatgtc aagtaatctt ctgttccttg gcgtccataa
    22621 tttggatgtt tgctttgaac cgtagcacct ttttccattg ccgttagaaa ttcaggcatc
    22681 aagtctcgtc ggatatcttt tacagcagca tctgcaatga ccgcatcgat caatgtccca
    22741 ggcataagtc cacgttcatc aggagacagc cattttggca aatagccact ttctctatag
    22801 ctgttcaaaa aaccttccag catttcttcg tatttttcta cagcaatcaa agaataaaga
    22861 ggataaaccg ttttatacgt atcccaaaac ccattatttg tatagagaac accaggtttt
    22921 atagatcgac tagtcgtatc atagtggatt ttttgcccac taggatcaat ttcataaaat
    22981 gtttgtggaa ataaaaacac ccgatataaa ttatgataaa acgtccgcaa ttgttgttga
    23041 tcatggtgtg tgagctgtat acgatcaaaa taggactgcc attgttcttg actgtgagca
    23101 aggtaagtct ctttgctttg gttttgttct agttccaggt tataagctgc ttgttccgag
    23161 ctgataaaag atgtcccaaa tcggatagtt tgtttttttg tctgttcaaa atacaacggg
    23221 atcgagtcgc tatttttgtt ggaaacagct aactcatcaa ttgttaaagg atattcaaat
    23281 ctcaatataa aataaaaaga aaaatcagga tcttctgaac cagcaaaatg tgtgattttt
    23341 ccttccactg tgtaaggatc tataacaaag agctgatggc gtcccggaaa ggataaaagt
    23401 aaaccgctgt catttttgct gtaatcaata gataagattc cgccatacat gctaggtatc
    23461 aatgtagaac agatgccata acgtaattga cagatcgaca gatgagtcgg gcaaaatata
    23521 ctttcttctg ggcggtaaga actttgagca tggaaaaggg tgttctcctg tagttttcca
    23581 ttgatcggcg taaacagcat atgactgaaa tcacccatcc aaggacttgg ttgatgggta
    23641 agacggtagc cttgaaaaac gcggtcatca ggatgaaacc accagctgcc gttttgatcc
    23701 gtagtttgcg gtgcaaaata attcatccca aaaggaacgc cagtataagg ctggcagttc
    23761 ccattagaga aatttggctg attcgctgtt gcatgtctag tatctatttg accgatattc
    23821 attttatttc tcctttgttg attgtctttt gatgaatgaa actggaaatt tactatcgga
    23881 tggtcgatct tttgtctcta accaagtgac caaagcatct cccgcaagct tacctaactg
    23941 ttcaaaatct tgtgcgatgg ttgtcagtgg cgggtcaaca agagctgctg cttggatatc
    24001 atcaaatccg ataattgaaa aatcttcagg gatatgataa ccatgctgtc tcaagagatt
    24061 catggtctgg atagcgacaa catcgttttc acaaacaaaa gcagttactt catacttagt
    24121 gatataagaa agcaattcat ctaatgtcgc gcttttgtca tccagtgaag tgtggaaagt
    24181 caaaccagct ttgtccaatg cttcaaggta accaaggtaa cgctgtcgaa cggattgtgg
    24241 atgagtctgc gtaccaaaca aataagcgat ttttgaatgt ccctgttcga tcaaataaga
    24301 ggcagcaagc gcaccgcctt ggaaattatc ggaaagaacg gtaggaaaag gtaactcata
    24361 gattttttta tctaatatga cgacagggaa ttctttcaat gaaagctcaa aaagtaagtc
    24421 aagatgttgt tctgtatcaa gagcataata aatcaatccg tcaaattcat tgattagctc
    24481 ttttgctgtt ttattttgta gaaagtcaag cgtcgtcatc atgacatcaa tctgtttatc
    24541 ttgcatcaca gggttcaatc ccttgctaaa atcaccaaca gacaaatcag cgacatatgg
    24601 aagaagaaac agaatccgtc gtgtttttgt aggagaagca agaatctgtt ccggagaagc
    24661 ggatttaacg aaactgcctt tcccgcgaac gcgataaata agtcctaatt gctctaattc
    24721 agtcaatgca cgtttggaag tgattctgct tactttatag gtacgtgaaa gttctttttc
    24781 agttggtagt tggctgtcta caggtaattc accagttaaa atagccgttt gcaaatcatt
    24841 aaatattgtc tggtacaatg gttgagtcat ataaacacct cttaatgata tatcatattc
    24901 aaataatacc ataatggatg aaaaagtaaa taaaaagata ttttttgaaa gcgtagacat
    24961 aattggctgt atgaagtata atctttaaag atatatcaaa tagaaagaag gttttattag
    25021 tggtttataa agatatacca aaatcggtgc agaaatttat ggaagatatc acacaaaaat
    25081 gtggggatat ccatgcggac tgggcaaaga attttacagc agcatttgcc aatactctgt
    25141 tgacaacagt caaaaagcaa aatgacggaa ccaccttttt attgacggga gacattccag
    25201 cgatgtggtt aagagactct actgcacaag ttcgtcctta tttagtgatt gcaaaagaag
    25261 atgaggaatt agctgacatg atcagcgggt tagtcaaaaa gcaatttttt tatatcaata
    25321 tcgatccata tgcgaatgcc ttcaacgaag aagctaacgg tgctggccac caaacagatc
    25381 atacaaaaat gaacgattgg atctgggaaa gaaaatatga aattgattct ttatgctacc
    25441 caatacagtt ggcctatctt ctttacaaaa atacaggaaa aactgatcaa ttcaatcaat
    25501 cttttattga aggtatcaaa aaaatcttgg acgtgttcaa aacagagcaa gatcatgaac
    25561 actctcctta tacatttgta cgagacacga caagaaaaga agatacgctg atcaatgacg
    25621 ggcgaggtgc aaaaacagct tttacaggaa tgacatggtc tggtttccgt cctagcgatg
    25681 atgcttgccg ttatggatat ctggtaccat ccaatatgtt tgcggtggtc gtgttaggtt
    25741 atgtggaaga aatttttcaa acgatactcg atgataaaga aattgtacag caaacacaga
    25801 aattgaagaa agagatccaa gaggggattc agaatcacgg acgaacggtt aatcaaaaag
    25861 ggcaaacgat ttatgcatat gaagtagatg gaatgggaaa cgccacagtc atggatgaca
    25921 gtaatgtgcc caatctgatc gccgcacctt acttgggata ttgttctgaa caagaggaag
    25981 attatctgca aacaagaaga acattgttga gtaaagaaaa tccatatttc tatgaaggaa
    26041 agtacgcaaa aggaattgga tcctcccata cgccagaaaa atacgtttgg ccgattgcat
    26101 tagctatgga aggaatgaca acgtcagaca aatctgaaaa agagcggata ttgaatttac
    26161 ttgtagcaac tgacgcagga acacacctta tgcacgaagg attcgatgtg aacaatcctg
    26221 aaaattatac gagagaatgg ttttcttggg caaatatgat gttttgcgaa ttagtcatgg
    26281 attactttga tattagagta gaaaagtagg aggtatcgta aatgaaaaag aaagtatata
    26341 tcatttctca tagccactgg gatcgtgaat ggtacatggc ttacgaacag catcacatgc
    26401 gactgattga attgatagac gatctactag agctatttga agttgatccg tccttcaaca
    26461 gttttcattt ggatgggcaa acgattattt tagatgacta tcttcaagta aggccagaaa
    26521 aaagacaggc aatccaacaa gcaatcaatg aaggaaaatt gagaattgga ccattttata
    26581 tcttgcaaga tgattttctt atcagctcgg aatcgaacgt gagaaatatg ctgattggca
    26641 tggaagaaag ccgtaaatgg ggaacccctg tcatgttagg ctattttccc gatacatttg
    26701 gaaatatggg acagacgcct caattaatga aacaagctgg tatttcagca gcagcgtttg
    26761 gccgtggtgt aaaaccaatt ggctttgata atcaagtttt ggaagcagaa aactattctt
    26821 cccaatactc agagatgtgg tggaaaggcc ctgatcaaac agcaatcttt ggtctgctat
    26881 ttgccaattg gtatagcaac gggaatgaga ttccagtaga aaaagaagca gctcttgcct
    26941 tttggaagca aaaattagcg gatgcagaac aatatgcctc tacgaaccac ttattgatga
    27001 tgaatggtgt tgatcatcaa ccggtacaaa aagatatatc aaaagcaatc catctcgcaa
    27061 atgaactgtt tccagattac gagtttattc attctaattt tactgactat ctggaagcag
    27121 ttcaaaaaga tgtgccagaa gacttaggct cagtagaagg agaattgaca agtcaagaaa
    27181 cggatggctg gtatacttta gccaatacag catctgctcg ggtttactta aaacaatgga
    27241 ataccaaggt ccagcgacag ctagaaaata ttacagaacc acttgcgacg atggcttatg
    27301 aagttagtgg aaactatccc catgatcaat tagattatgc ttggaagaca ttaatgcaaa
    27361 atcatcctca cgacagtatt tgcggttgtt cagtcgattc tgtccatcgg gaaatgatac
    27421 ctcgttttga aaaagcagat gaagttggaa agtatcttgc acaagattcc ttagaacagc
    27481 tgaccgcagc aatcgatacg accggattcc caaaagacag ctttccattt gtcattgtaa
    27541 atactgcagg aatggataaa actggtgaag cagaaataac catcgaatta gaaagaaaaa
    27601 gattcgctga aggaatacct gaacaactat atcaagagtt agaaaatttg cctaaacgta
    27661 agtatcatgt agaaacaaaa agtggggcca ctataccagc tattttatct gaagaaactg
    27721 tccaatttgg ttatgatttg ccgaaagacc gtttccgtgt gccatatatg gcaagaatga
    27781 tcaaagtgac tttaccatta gaaaacatgc cagcattttc ttgggaaaca ttcgcgcttg
    27841 tagaagggga agcgaaagca gaagaaaagg aaacaatgat tcatcagagt ggacgaatca
    27901 tcgaaaacgg ccctctacat ttgacgattg aaaaaaatgg taccattaca atggaagatc
    27961 gcaaaaacaa acgaaagttg aataatctgc atatttttga agatatcggc gatataggaa
    28021 atgagtatat ctttaaacaa cctttctgtg atcagccaat cctatccagt aacaaagaaa
    28081 actctgaagt aaaagtatta gtagatacac cggaaatagc aaaaataagt attctacagg
    28141 aaatggaaat ccctgtttct gcagacgagc gtttagaaaa agaacagcag atggttgtgg
    28201 aatttcgtta tcgaaaagca gaacgatcca aagaaaaacg aatccttcaa ataaaaacaa
    28261 tcatgacaat cagaaaagat agtaaaaaaa tcgactttga aacgactctc gacaatcaga
    28321 tgaaagatca tcgcttacgt gtcttgtttc ctacaaagtt acatgtggaa catcacgaag
    28381 cagatagtat ttttgaagtg gtgaagcgcc caaaccatgt gtctaaaagt tgggaaaacc
    28441 ccacgaatcc gcaacatcag caagcatttg tcaatattca tgatgaagag tacggtgtaa
    28501 cagtcggaaa ctttggtttg aatgaatatg aagtaacaga agacggacaa atcgcagtga
    28561 cgctacttcg cagtgtggga gaactaggcg attggggata ttttccaaca ccagaagcac
    28621 agtgtctagg tgagcatcgg ttcaattaca gcattgaact acatggacca gaagaaaaat
    28681 tctctactta tttgcatgca tacgcagcac agattccttt ttccactcaa caaatcaaac
    28741 atcatgaagg aacattgatt tcaaaacaac aatatttaac gataaaaagt gaaacgtttg
    28801 caattacagc tttgaaacgc agcaagttta gtgataaagt agtagtaaga ggtttcaata
    28861 tgtctagtca tttagaaaaa ttggaaataa ctaaagacaa tggaaaaact gtcatattga
    28921 atctgcttga agaaccaacg aagcaagcgg ttgtcccaat aatccaacct tatgagattc
    28981 ggacaatcgg attcgaggag gaaaacgaat gtatggcgga atagaagcag gcggaacaaa
    29041 atttgtgtgt gcggtttcag atggtggaga aattttagaa aaattaagta tccctaccac
    29101 aacaccagaa gaaacattgg atcaggtatt tgaatttttt gatcgttatg aattgaaggg
    29161 aatcgggatt ggctcattcg gcccgattgg tatcgacaaa acaaaagata attacggata
    29221 cgttttggca actcccaaaa aagggtgggc acaattcgat tttcttggca caatcaagga
    29281 acgctacaat attcctgctg cttggacaac ggatgtcaat gctgctgcat atggggaatt
    29341 gaagcaagga gcagcacaag gaaaaaatag ttgtatttac cttaccgtgg gaacaggaat
    29401 cggtgcaggt gtcgtgatca atgaagaaat tttttcaggg atcgcacatc ctgaaatggg
    29461 acatatttgg gtgaaacgcc atccagatga ccattatgaa ggtacttgtc cttatcataa
    29521 agattgttta gaaggattag cagcaggacc gtctattgag gcacgcacag ggatcaaagg
    29581 gcaagatctg ccgcaagatc atcctgtttg ggctattcag gcttattata ttgctcaagc
    29641 actgatcaac tatacgttga cgttagcacc tgaaaagatt attttaggcg gtggggtaat
    29701 gaatcaggat catctccttc aaaaaatccg tcagcaattt gttgaattga tgggtggtta
    29761 tatggaaaca cctcaagtaa gtgaatatat cgttcgttgg ggactgccga atgaaagtgg
    29821 gattatcggt agtttgctgt tagcagaaca cgaacatcaa aagtaagcag acaaattaca
    29881 caaaaagaac agagtcttat cattatctgc tgataagact ctgttctttt ttatttctat
    29941 tcccataatc caggtaaagc tttaccgact attttttctt gagtaaatgg atggatcatg
    30001 tgcagttcta atgcatggag catcagtcgt tcagctgttc tattttggta gagagggtct
    30061 ccaacgatcg gatgtccctt atgagctaaa tgaactctga tctggtgtgt acgtccggtt
    30121 tccaaaacac aatagacttg tgtttgttca gaaagtactt tgttgacagt gacatgtgtc
    30181 aaggcgctct gaccattttt atcatctacg accctttttc tccgatcatg gcgatctcgt
    30241 ccaattttat tggtgatggt catatctttg gcaatttctc cccatacgat ggcttgatat
    30301 ctccgataga tcattttttg ttccaacatt cttccaagta tcggcaagac aaatggattt
    30361 tttgcaaata aaacggcacc gcttgtttct ttgtccaagc ggtggacaac gtaaggtcgt
    30421 tgctgtttag tgtcgagata agcagctaaa tgattgagta aggtactgtt ttctgtcggt
    30481 tcatttggat gagtcttcat tcctgcaggc ttatccacta taatcaaatg ctcatcttca
    30541 tataaaacac ggatgtgctt cgcatctcct aattgaactt cttgataatt ataatctgtt
    30601 tcttcgaata acaatgtgat ctggtcattg ccctttactt catgatggaa caaagcaggt
    30661 tgttgattga tccaaacgtt tttacgtata cgcaaaaagt gtcgaacctt tctaggaact
    30721 aaccattcct tttcaagcaa gtcgcgaatt gttgtttcag gatggttcat aggtaaagtg
    30781 atcgtgattt tcacaagtgt actcctttca gtgcaattgc agactaattg taccattttt
    30841 aaaacatatt taagaaaaaa cttacatttt tctgttcatt cttatgttac tctacttgca
    30901 ctaacgtaaa aaaacatatt gaactacaac ttaagcagga agaaaacact ctttcactat
    30961 ggtaaaataa gacgattgaa tcaaatagac aggagaagaa gcaaatggat tttcaaagca
    31021 ttttagaaaa gataaaagct gctttgatca gtttttggcg ttggatcaga ccatatctcg
    31081 gacaattcca tcgatggcga aagcgcatct ggaaaaaata tcatgtgaac aaattgattt
    31141 tgctgattgg tttgatctgt gtcttagtga caagtatcta cctctttatt ttagcaaaac
    31201 aagcaaatgt cgaaacgtta aaatcaggat taagccaatc gacagtcatt tatgataaga
    31261 aaaacgaaga agctggcaca ctgtacgccc aaaaaggaac atatgtagaa ttaaacgcga
    31321 tttctcccta tatccaagat gcagtaatct cgacagaaga taggaatttt tacgagcatc
    31381 acgggtttga tatcaaaggg attgcccgtg cagcagtccg aatggtcttg tctggcggaa
    31441 catcaggggg cggaggaagt acgatcactc agcagcttgc caaaaatgcg tatctgacat
    31501 tagaccaaac gtttgatcga aaagcgaagg aattattttt ggcaatcgag atcgaaaaga
    31561 agtacagcaa agaagaaatc ttgaccatgt atcttaacaa tgcctatttt ggcaacgggg
    31621 tatggggtgt ccaagacgct tccagaaagt attttggagt agatgcaacg aatgttacgc
    31681 tgtctgaggc tgctactttg gcaggaatgc tgaaaggtcc tggtatttat aatccgatcg
    31741 atcacccaaa aaatgcgaat gatcggaaaa acacagtact aagtgtaatg gaagaaaacg
    31801 gaaaaatcac aaaagaacaa gaacaagcag aaagccagac agatatcagc gcgtatctta
    31861 atgacacata cgataattca gattctggtt atcgttatcc ttattatttt gatgcagtga
    31921 tcgatgaagc agttaacgag tatggtcttg atgaagaaga tgtcatgaat aaaggctata
    31981 aaatctatac agctttagat caggattatc aaaagcaatt agaagctact tatcaaaaca
    32041 gtgcattatt cccagcaaat gcttcagatg gtgccatggt ccaatctgct tcagtagctt
    32101 tagatccgaa tacaggtggt gtacaagcac tagtaggacg aagaggagat catgtcttta
    32161 gaggattcag ctttgctaca cagatgcgtc gttcaccagg atcaacgatc caaccattaa
    32221 gcgtatatac accagcactg gaagctggat acaagccttc cagtatcttg aaagacgaac
    32281 cgcaaagtta ttacgatgcg cataattttg acgggacata ccaaggagaa gtaccgatgt
    32341 atcaagctgt tgcacaaagt ttgaatttgc ctgctgtatg gcttttgcat gagatcggtt
    32401 tacaaaaagg atatgataaa gcagaagaat tcggcctgcc tttagcaaaa tctgataagt
    32461 attatggctt agcccttggt ggactggaaa aaggagtatc tccattgatc atggcgggtg
    32521 cttacagtgc atttgccaat gatggtcaga tgtatacgcc gcatcttatc acgaaaatcg
    32581 ttgattcgac tggagcggtg atcgtcgata acacaaacaa aaaaccaaaa caggtcatat
    32641 caaaggaaac agccgatgaa atgaccagca tgcttcttgg tacattttca aatggaacag
    32701 cggctgctgc gaatcctgca ggttatacga tagcagggaa aacaggaacc acagaaacta
    32761 atttcgatgc cacaaaagca aatgaccaat ggatgatcgg ttacacgcca gacgtagtga
    32821 tttcgacatg gatgggttac gaagaatcca gcaagctgca ctatttggaa gggacaagtg
    32881 gaaatgttgt cgggaaagtc ttcaaatcag cggcagaagg catccttccg tatacttcaa
    32941 aaacaggatt tagtgtagca gatgcctatg ccacaggagg acaagtggta gctgcagatc
    33001 aagttggaaa cacaggaaat tctaatggag agtctggaaa ttggcaagat aacttgaatc
    33061 aatatggtga acaagcaaaa gaagggctga aaaacttcgg cgatatggtg aaagaaggcg
    33121 ttcagggaat tggtgaagcg gctaaagacc tctggcggaa atatcaagga gagtagcccc
    33181 tttgaaaacg aataacccca tgttacaata gagagtaact actaaaagaa aagagggcat
    33241 aacatgtcaa acatctacga tagcgcgaat caaatcgaac gtgagatccg tgaattacca
    33301 gaattcaaag cgttgaaaga agcgtacgag aaagtacaag caaacgaaga agcacacaaa
    33361 ctgttcaaag acttccaagc gatgcaaatc gaattacaag aaaaacaaat gagtggacaa
    33421 gagttcagcg acgaagatgc aatgaaagca caagaaatgg ctgtgaaaat ccaatcagaa
    33481 gaagtaatca atgacttgat gcaaaaagag caaggcttca gtacaatcat caatgacttg
    33541 aaccgtatca tcatgacacc agttcgcgac ctttacagcg aataaaacta ttttatgaaa
    33601 caacagaggg tgtgaaagag acgttcggcc ttgagcgatg acaaaattgc ttcttattgc
    33661 cgataggctg tctcttgaac accatttacc aagaggtcgt gagcctaccg tttaactctg
    33721 agttacaagg aacaatttca aaaaacagct tctcatgttt gatgactatt gtgacttgtg
    33781 accgaggagt tggcaggaga acaccgttta ttcagaaata ggagctacga caaaagtctt
    33841 gtcatagctc ctattttttg tcattcattt ttcaagcggt agaaatagcc tttttgagct
    33901 aacagttttt cgtaagtacc tatttcaacg atttttcctt catcgatcac aacgatttta
    33961 tctgcctctt tgatcgttga aagccgatga gccacaataa aagtagtggg tgtttctgtc
    34021 aggtaattca gggcttgctg gatttttttc tctgactggt tatctaaagc tgaggttgct
    34081 tcatctagca aaatgatttt tggctgacgt atcaacgctc gtgcaatgga gatacattgc
    34141 ttttggccac cagacagctt gttgccatgt tcgcctacta aggtatccag accatcagga
    34201 agctggtcaa tcagtgaaga aagttgcgca gcttcgatga cttcatctaa acgttctttt
    34261 gatacgtttt tcaagccata agtgatgttc tctttgatcg aagcggagaa caacaaagtg
    34321 gtttgaggaa caacggctaa ataatttcgc acacttcgca tatccagttc atccaaaggc
    34381 tgatcatcta gaaaaatttt tcctgaagtc ggctggataa atccaatcaa taagttaagg
    34441 agtgtagatt ttccagagcc agatggccca acaaaagcaa ttgtttctcc agctttcacc
    34501 tctagagaaa aatgatcgat aatcggtttg agtgagtccg gataaagaaa agaaacatcc
    34561 tcaaaacgaa aatttccatc caaatgttgg atttttttct taccgtgata agtttctaca
    34621 tcgccagcaa tcaacagttc gccaatagaa gtgatagatt ccatgccttt tgaaatcgta
    34681 ggaatcagcg tgatcattcc agaaacggaa ttgacgatcg tcgtgaaata cgtctgatac
    34741 atcacgacat cgccgggttg gatgcgccct tgtaaagcta atatcccagt gaaaatcaaa
    34801 caaatcagct gaaatatctg aaaactagcc cagctgactg atccgaaaac agattgcagg
    34861 atatctaagt ggaatccttt ttcatagatt tgagtaaaat gcttatttaa gcgagttgtt
    34921 tcgtgttttt ctaacccatg agctcgagca atcggtgcta attcgatcac ttcgatcact
    34981 tttgcagaag tctcttccat ttcttgcctg aagtctgagt tggactgtct gatcctttta
    35041 cggaaaaaga gagtaacgaa tgcggcgaga ggaacagtca ataagaaaaa catgaaaaca
    35101 acaggacttt tataaagcgt gatacctaaa gctacgaata aattgacagc gatatttaat
    35161 ccgctgacaa atacttgaga ggacaacgtt tggatagctt ctacatcacg gatgatcttt
    35221 gactggattc gtccagattg caattctttt tgataaggaa tagatagttc ttggattttc
    35281 ttgataaggg tcgctcttag tccagcttct acttgacgga tcgaagtgct atggtatttt
    35341 acatgaaaat aattcgtcaa tatattttga ccaatcagac aagccatcaa aaaagcgttg
    35401 aaataaatgg cctgcaactg agaagaatct ttcgatgaag ctgcattgat tacattggca
    35461 atagcgatcg gcattaacca agatggaaga tgtttgataa taaaaaagag tcctgacatg
    35521 gcaaaacgcc aataatttcc ctgataaaga tgcagcaatg tctgaaaagc atttgcatga
    35581 tatttttgat aacttttctg tattcgttcc tccataatct tctccttaac aatcttggta
    35641 aataaactgc aagtgttcta ttgcttcagg aacataaatc tcaggagtag cttcaagagt
    35701 ggcgtacatt agaggacgct catatttgat ataatgcagt accgggcgga aatctaaaca
    35761 gcccttgcca acaggtacca tgcggatctt tccattttcc atgatatagt ctttgagatg
    35821 aagcgctgta atataaccat gtaaattgtc caaggcacct cggatcactt tttcctgatc
    35881 agcatgattt tctttatgca tcaaattcgc acaatctaaa atgattttta aatttggtga
    35941 agctacttca tcgattaaac gtttagctaa ctgatagtta tagattggat gattgatccc
    36001 tgcttcaaca gcaacagtta cgccaaaatt ttctgcatga gcgactaatt caatgataga
    36061 atttctggcg atctgataag cttcttcagt aaaattttct tttgtgtaac cgacagagac
    36121 actaccggtt tccgtagcaa tcatcttggc ttgataggca gagcacagag caatttgctg
    36181 tttgaaagtt gccaatgctt gtgcacgaac ttcttgattt ttgctggata ggttgatata
    36241 gcatcctaaa atggaaagtt cgatattgtt tttttggaag tattcaccaa aataggcagc
    36301 actcccaagt gtcatgtcag ttaatttaag ttgttcagga aatgcttttt gtggtgcaaa
    36361 ttggatatgg gacaagtgaa gctgtgatac tttttgaacg atttcttcac gatttcgaac
    36421 atctaaatcg tgggcacgga tgcctaaatt taatggaaac atctcaaact cctttttgta
    36481 aataattagc aagaggcaga cgggattctt ttatcaattc aacaattatt cgggcaactt
    36541 tatcagcgcc ttctggacta aagtgggtat tgtcttttag tccttctggg taatttttac
    36601 aagtatcagg cataagatgc aggtagaatt tttttgtctc ttcttttgag aaggtctgga
    36661 acaattcttg tgatcttgag aacacatcta aaagaggaat atggtgtttc tcagcaaatg
    36721 cacgcatcgc ttttggatag tctccaagta tatctggatt caatgttccg ttttctaagt
    36781 aatctcgtcg cgtcacagat gtcagtaaga ccatttggac gttcgctttt tttgcgcatt
    36841 caaaaaatat ctgcagattt tttaaatagc taccgaaggg aagcgtacct ctttcttctt
    36901 ggattttctg gtcgttatgt ccaaattgta caaataagaa atcattcggc tgaaactgtg
    36961 aagctagacg ggctaacctt ccttcctgga taaatgattt ggtgctgcgt ccattctttg
    37021 cttggttatt gatctggatc tcgggtgaaa aataagcaga gattttttct ccccaacctg
    37081 tctcgggacg cttgttttca tctttttctg ccgcagtaga atcaccggca atatggatag
    37141 taggcatgtt atctcttctt tcataaaggt ttataggcaa tgaagcagaa cagcaagaga
    37201 agaagacgga gcaa
//
LOCUS       DAFTHM010000018        37107 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFTHM010000018 DAFTHM010000000
VERSION     DAFTHM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.018"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            83..1081
                     /locus_tag="L7C88_000898"
     CDS             83..1081
                     /locus_tag="L7C88_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBP9557748.1"
                     /translation="MSNAKFNPQAFQTKPPKQQKEKKQKKRFLFQKKKTEPSDRMIQF
                     SQKSAMSVFSGAFFCLFLLMGVVLLLNFGRVDTLTRLAVKKQVNPETLLTEVNQTLSS
                     TEQLKYEGQHFIERLFTYSPEKRNEWEASVNHYLAQGLEASDLGFVTTATNRVAKDVR
                     FIKLEEIDLTQAMYRLFYEVTFTEGEHWKSSQLSFPVSYQNNVLKVLDGVQFLNLSES
                     KNTNSVNYQENRFYSSGQAVTESEEIKLEAFVKRFFELYVKNDEKLALISNEKGLEGG
                     ELINVQLDHAVKNKEGNYFLQGKYRFYFEKGNEFQSNFSMEVKTSGDSYFVTTLNE"
     gene            1105..1389
                     /locus_tag="L7C88_000899"
     CDS             1105..1389
                     /locus_tag="L7C88_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557749.1"
                     /translation="MKLFDLKSLFDDVSGQVIWLLAIVAIVLMVGAYATQGFARAAFA
                     IIGVFILIMLVLLLSNAVDIGEWLKNIIFIKDSEENVGVTQMIVPWIQLS"
     gene            1470..1868
                     /locus_tag="L7C88_000900"
     CDS             1470..1868
                     /locus_tag="L7C88_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBP9557750.1"
                     /translation="MEYNYTKEFKHPHKIYGIKGQKIPWISNGIRMEQLVIGGVFLFI
                     LLILFLIAYVNQISFLQTLFRKSWLIMIFGIGVLVWTLFSMKWDNKHFFEYLIGRTSY
                     YQKRKQRFEHEMYVPFFHEKVTYSLHKWKE"
     gene            1878..4421
                     /locus_tag="L7C88_000901"
     CDS             1878..4421
                     /locus_tag="L7C88_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBP9557751.1"
                     /translation="MAFLFLLVVFIIGIWQFKKKKTKLPRLEFPIDAIIRNFVLTKND
                     DVWVGYQLSSQVFPLNDIDFFKNYLQDGEGILGHDEYDYHFINIPRQFNLDTHIEETI
                     RDLVKGECADLGKVYFEQAGKILKDEVQLNEYRTYLFVRFTTEMKVSDPIEYFQLLKH
                     VFKKFIYRITGQRVPISSVLPTYETLEKELYTELSNYKPIERLSAQEIGQIYYYFFHR
                     SEEKLPERQLTPMEICEGVISNEAGYIAIEQLNQTHYSTFLSQTDAPLAMYGSSFIQN
                     LQDSLSFPIDTHIRLRFEHSKSDERKINKMAGRIYEQEKEYETVDGILDSDDVLNFGT
                     ERLMDVKDKLKRKEKRLCYSTVTLVVSASSKEELEERVKDIEFAIESTDFKFYRSVAD
                     QLTLFNQCLIGSTQRFRSYEQVATTGFVADYGLDLKKEVGNKKGFPLGRIVIAKKFKS
                     AKEALALSSKLVWYYPNLTKKSIEGAEHTNGNTLIIGPPGKGKSVLVKYIFLWLMFLG
                     QKILYIDPKNETQKFFLKALEKFGHIPEFVAMYERINFISLSSDESCRGMLDPLLFLP
                     KEEAIQTAKNVLGMLGEVDTNRETASHKKTVIQDAIDVVYTMPGKHSLSQVIEEIRKS
                     DKELAKLILGHSVGLGKILIGNEHSTPIRFDSQINVLGTQGIRIPTQKESDSGRLNSE
                     QLAGMAIMEVIMKFTYIFSTNKEEDAAIIYDEAKGYEDTAQGSYLIDDSLRKGRANNT
                     DIYLVVQAFKDYDQEDKKELISYKFAFRPKQKEAREKLLSFFDMEVNSANLEMMEQLQ
                     TGTCLFQDHLGRNQPIAIDVLFDSWLLAVSSTENQDEKIQAMLENEKQR"
     gene            4443..6785
                     /locus_tag="L7C88_000902"
     CDS             4443..6785
                     /locus_tag="L7C88_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557752.1"
                     /translation="MRKKSLKWWTLLLLGGLFFCLQGATVSADQMNDGAGVTETDRSE
                     GENANDKVEVKEVTTDVDQLYKNYKKNSFELMTNDYESMNLKKKLSYNVAGVMKNFVW
                     SGVKMLGEFNASMVEFLFELDIISAIREPIQNLTQKIADNMLSIAGTIGISFSAIMMA
                     IKYAGEARMKQALRVFLMTILIFTGLSVLKDSGTNKNLFDVLFSLDSTVETAFVKVNP
                     VLTPEEETNYETKETEEVTADKKVETAGKLMAARVFYSNVYEPYLLLNYGTTNVDTIR
                     EKKVKYAGKEYDRINLLLDNDLGTKIGEKIHDKVTEYEADTLKNKNIQYYNSWKNTAF
                     ALFYFVVNLIQTVVYFVLSMFRLIIGTMQLLLVPMLPFLLFLGLFLVTMNVFGNYAKV
                     FGILTFLKGMTGFACILFSSFLSYGFQLSSTQDDPWEKILLIIVYLFAPLGIYLFRGF
                     LGSLFTGRMGVRGALAFAGNPFGAEAKLRREAKQRLKERKEARKAQKQKEKENARKRQ
                     ERQRKRGGGSDVRMPQTAKQATRSAFRRESAQQPRHKAPNRMERMAQKARDLHDQAKQ
                     AEEQSQERMQRTAMEKQARKTADLLQRELQGNPSLRERSRKGASRSPYRNQGSAMVVS
                     LANPKQKHKSYGQKHTPRTELNDRKRRQGQTSRRRKEALTPVTKTSSMKTRTVAGQKH
                     AVQKPLRKGNVPRATGSTTPKSVRRPEGVREHMSAVNRVTAQTKAPSTVSKAYSTMKQ
                     TKSPKQAPKTRSEFRATQAKMKRKREKQPIYRREMKQRKR"
     gene            6801..8975
                     /locus_tag="L7C88_000903"
     CDS             6801..8975
                     /locus_tag="L7C88_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 family protein"
                     /protein_id="HBP9557753.1"
                     /translation="MMNAPKRPTHFEQMFSVDRKRKQEKETPKSRFQQLYFIVTLLGV
                     CLYPFFIVGSIPLAIVFMIDKKETRAHIYDFEYESFLKRRSSLFFIFALGFTLLNLFC
                     FIFVLPRGYLSCYLLFPLNLFSHALQFNGQTIFALLLGGTGAGSCLIAYASFIEKRKV
                     VSKKERQTALLNSKEYKERRKNKFQESQKYTAEYQQAYQVAIVIKDVALRNKQLASLA
                     KVILLGTDEYGLPYVMNFSELNQHVIIPATTGSGKTTVIQLLAEHACKFRIPVILVDG
                     KGAGETLQALKEVAEAYNRPIEVFVDGGDLRYNPVKNGNDIAIRDKLTNLAETESVYY
                     STAAKALLQVTIQLLDEFQKSHKIERNLVWLQHYLLPRNVLHLFADRIQLKNPDLFKE
                     KVVVEKKKTTKKKTKKNEAMDKTERDFADVEQLSEERIVEHDRKTVDLETYYLLLKEN
                     ISLMTEIEQTLFKRLFVRYEHKKNPFYLYATSENLQTNINMLLDSELGELFDTSGGKR
                     ELDIQEVVKEGKIVYISLNGLIYSEFIRTLAQMLVGDINFFASEVYKQAGETANRSKV
                     LVIFDEPASYLNDNLIDLVNKGRGAGVHAAYAPQTLADIDRIDPVLRKQLIGNVNTFF
                     IGKTNDPTEIDYWADLMGTEEDIELTEMTTQEAGYSDMGKVDWTGERGTKRDVDRFKF
                     NPNRIRALRTGEFVVYRTAEDVQEPPRVVYIRKPNLEKQYAK"
     gene            8965..9387
                     /locus_tag="L7C88_000904"
     CDS             8965..9387
                     /locus_tag="L7C88_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBP9557754.1"
                     /translation="MRNKKVIVRILIVSFLLFGCFKLIKTNEESNGKLINSNLEEVLE
                     LQKTNQSFFVYLARNDCKKCQEVESFLERYDKKFSRNVYRIETRKEPRQEELQTFLQR
                     YHVKSVPSFLVIHDRNVKKIERKTFFFEKTLNQFLPNF"
     gene            10330..11241
                     /locus_tag="L7C88_000905"
     CDS             10330..11241
                     /locus_tag="L7C88_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-relaxation family protein"
                     /protein_id="HBP9557755.1"
                     /translation="MKYLLHGYFIDYSTRNSSTLAILCLLHELRVVTRKQLYKLLNFD
                     RSISKQGVTNALVRLYEKQLIDRKKYGTEMYYYLTKEGHQSIGGYYTLPKVPEYNLNH
                     HLQINNYLIKGMALAKDHPHLKRIISERRTVYETKDLNPKTKGRKFFVPDFIFRFRDK
                     ENHEINWSFEIELTLKTRRRYREAIFPKYIRELRTRPESHLIYVTPSGAIQEELHAFK
                     RIFFKRETEKDASQQELFERLHIFSALEFEEGLKALLENDPAVNWRTVEREKIYPNGA
                     VQSRLNLFEESTENEEKPKVKFTPEVL"
     gene            11728..11994
                     /locus_tag="L7C88_000906"
     CDS             11728..11994
                     /locus_tag="L7C88_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557756.1"
                     /translation="MTTKNEQLKEQARKELQERGLIIEGSFEGDFETYIGCYARPINK
                     PTALDPMNEQEVKEQEKHAVNGFPQDFTEWYEWEINNGKLENFL"
     gene            12066..12407
                     /locus_tag="L7C88_000907"
     CDS             12066..12407
                     /locus_tag="L7C88_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557757.1"
                     /translation="MAKNTPYQVGDIFYSSWGYEQTNVTFWQIVKLTEKTAWFQPIQK
                     KTVEHYSSMSGKVVPMKDKFIEYPLAKTKDSIVKKRIDPETYPDMLCGYRSWDTFHRY
                     KNQAVYESSYY"
     gene            12462..12881
                     /gene="ssb"
                     /locus_tag="L7C88_000908"
     CDS             12462..12881
                     /gene="ssb"
                     /locus_tag="L7C88_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBP9557758.1"
                     /translation="MMNSVNLVGRLTKEVDLKYTPKGNATGTFILAVNRNYTNANGER
                     EADYIRCVIWRKAAETLAKYTGKGSLIGINGRLQTRSYQNQQGQTMYVTEVLVTDFYL
                     LESKEINEQRSKSMANNQNNSSIPGNEIQISDSYLPF"
     gene            12958..13254
                     /locus_tag="L7C88_000909"
     CDS             12958..13254
                     /locus_tag="L7C88_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557759.1"
                     /translation="MKIIDSYDQRTMQYLGSFDYTDENIINYVASLPPYQSVRLVDFA
                     SDELVLTTMGNFLDYVGDKKWLEKILSKLIAKQTGEEPINAIQLFNRYEQENND"
     gene            13269..13700
                     /locus_tag="L7C88_000910"
     CDS             13269..13700
                     /locus_tag="L7C88_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBP9557760.1"
                     /translation="MKRLKRSIFIVLALIDFVGTGCEAIDVQKAPLSEIKQAITKQDE
                     EQPLNTQVEIVNQNKPSFSEEDFSLENGTRQFFSDLDRLNRVGVASALLHKSRMPTEE
                     RDRLYIKPTGWKQKKMKNGDYLYNRCHLIGYQRATSFPISM"
     gene            13882..14187
                     /locus_tag="L7C88_000911"
     CDS             13882..14187
                     /locus_tag="L7C88_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557761.1"
                     /translation="MKLDMPGRYKLLRVRLFLIKLTNLRMYGSITDLYSKDIRLRMQR
                     TLSKSKNVGHEIRDGRLAVYLSRVGKTCLIDSDESGNATKRFTEEIEQLAELNIRYF"
     gene            14591..15079
                     /locus_tag="L7C88_000912"
     CDS             14591..15079
                     /locus_tag="L7C88_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBP9557762.1"
                     /translation="MKKTIFVLAIFICFGLLLVGYLLFNSNEMRTISTNDLLKKSELK
                     DKKKESLAFIMFTQEECEYCIAINPIIDSVNKETLNKIKKYDISVDFQSKQKCKIKFV
                     PTIVAYSKNKEVGRIDNELDNLYRKKQDGSIVIDKKKTKTLLIDWMKKMDKQGEYLYG
                     ED"
     gene            16413..16715
                     /locus_tag="L7C88_000913"
     CDS             16413..16715
                     /locus_tag="L7C88_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9557763.1"
                     /translation="MTKLGITLDDNIYDEKILLSGGEKQKISLARALIKSASVIILDE
                     PFRNLDNETRDNLRDYILNTKKEVCYIIITHDHILDNFLDSNDEILYLNKEYDNNE"
     gene            16708..17736
                     /locus_tag="L7C88_000914"
     CDS             16708..17736
                     /locus_tag="L7C88_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBP9557764.1"
                     /translation="MNSKKLQMGEIVRGPSQISIDVTYKCNFRCKHCYNASGGDNCFM
                     DNELTDDELLELTKDICNLKPYNICFCGGETLLRKKIVLSCATLLKEAGIPNIAIVTN
                     GSLVTQDVAKELFKAGINRFQVSLDGKNASSHEALRLYPNSFEKAINAIKLFRELSEE
                     VDVAFCPTSFNYNQLREVYQLVNTLKVKSLRIQPFMLSGRGMQNREIVPTVSQYRKLV
                     SDINYIKRNEDYTKIDWGDPIDHIIRHRTLLKDFSNFVSIRSDGGLMASPYLPIQVGN
                     IKCHSLSKYWRAGLYKVFSLDLVQDIATQVSSIQDMSKELKKGHIKWLNEDIEIDILD
                     EYKHDILI"
     gene            17792..18010
                     /locus_tag="L7C88_000915"
     CDS             17792..18010
                     /locus_tag="L7C88_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557765.1"
                     /translation="MISEPQMNNMYESPTIMGAGEAAPRACSAIMVCVLLASAGVGIQ
                     AGAVYTYAVVATVAVAAAAVWKTVGLVG"
     gene            18081..18896
                     /locus_tag="L7C88_000916"
     CDS             18081..18896
                     /locus_tag="L7C88_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557766.1"
                     /translation="MKYNNLKPKLLNENIEYIREENYGYLTIVPKNGTELKDNVFNPT
                     VRYILANCTGKNSVKKIANGLKKKFPSLEYEKFYQDVVGTIKFFKHYNIIDIGDYSME
                     EKKIYKIEQNLELELLNESHYEEIYNFITDHPESMYFHEDIYHQGNSKELEVVLRYNL
                     FSFTSEFYFLRHKERIVGMVSIIVNPFQNLSYSIVNYLICEPAYTTTILTTVLENINE
                     VSILEVKKLVIHLLNSTEDESLIPYLKDSHFFKEAVLSKEYREHDVLRYAYIY"
     gene            18960..19145
                     /locus_tag="L7C88_000917"
                     /pseudo
     CDS             18960..19145
                     /locus_tag="L7C88_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347581.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
     gene            19719..19982
                     /locus_tag="L7C88_000918"
     CDS             19719..19982
                     /locus_tag="L7C88_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557767.1"
                     /translation="MFIKYGADTVATMFTEEYQVDYYEVIDKCVHFVYEKVWNFMNFA
                     ISEEILRVQENRTGIFTRDRKLNLIAHYIRNRWSSIPNFNYKK"
     gene            20316..20687
                     /locus_tag="L7C88_000919"
     CDS             20316..20687
                     /locus_tag="L7C88_000919"
                     /inference="COORDINATES: protein motif:HMM:NF016724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBP9557768.1"
                     /translation="MWLSDEKIQWRSYQKRILTNFATYLNNNSVHLVAPPGAGKTFLG
                     IEMIRRLDCKTLILVPSLILKKQWLTTIEEYFLVNPADSCYLSGAIEHPSHITVETYQ
                     TIYNRLKEEPTYGDQLELLVF"
     gene            20867..21289
                     /locus_tag="L7C88_000920"
     CDS             20867..21289
                     /locus_tag="L7C88_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557769.1"
                     /translation="MVKEEVLCPHQDFLYLIPANQETTQHYFTFLEKQNELVEALMES
                     QETVDYLLSLEFVQHPLEHSKEIYENFELFTSALIYLNHHNYELIPEHWQLLGSSKQQ
                     GKKASVPSLGKKELITIYQQMFEDQPELPIFYQLKKAG"
     gene            21434..21679
                     /locus_tag="L7C88_000921"
                     /pseudo
     CDS             21434..21679
                     /locus_tag="L7C88_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21788..22744
                     /locus_tag="L7C88_000922"
     CDS             21788..22744
                     /locus_tag="L7C88_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557770.1"
                     /translation="MLILANQASTFVQTQQLRGRGLRLGAQNKVTNIWHLAIGLPGVP
                     LSEQPDLKRMLRRLGNISGLTFESSPKIESGGDRFALPLEYTTTTMETYTQSMFYFSC
                     ERSRLKEQWSTALADGWHLSMPIVVRKVDQVKQKQETSLPIVVKNIEPLSFWSAIFKG
                     NLLEYFQIRRRQKLWEKECARKKSLAICVQTTLQRLGEVSDRKVIVAADQQEFRCYLE
                     NAGYREGQLFTEAMRELLAPLENPRYLIEGKKIVLTVPERFGRNKQIANLFLNELNQS
                     SLPKCQLVYTRNPEGRQKLVTYRMRQVFQTRDEVIIQKNIWT"
     gene            complement(23580..24251)
                     /locus_tag="L7C88_000923"
     CDS             complement(23580..24251)
                     /locus_tag="L7C88_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBP9557771.1"
                     /translation="MTIKTSLQNQAYQSIRQQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRHQGLVDTIPQSGNYISLIDLDLAKNARFVREHLERQIMLECCAKMNNQ
                     KKQVLETIIAEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLEDNNTHLERF
                     RWLRVKTEGLKWEKIMEQHHQLFKALTMQDPEEANFLTSLHLHLMLDEQNVVLTTHPK
                     YFKNI"
     gene            24568..26199
                     /locus_tag="L7C88_000924"
     CDS             24568..26199
                     /locus_tag="L7C88_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBP9557772.1"
                     /translation="MVLIKDWQDSIEGLNKMQVQLPYFNVEAVKQEGQKHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELESGVVVCETFDEEVVEKAYHDYNNDILEIVMGEDGEL
                     KKRLLAVTADSLYCNPKNITDYQRVVKYFEDPTLQFTTFTITEKGYSLKDSKGQFFSV
                     VEADIKSGPTNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFMIAE
                     AWQKKGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSESVKMDLLKAGFEDLDIIHTA
                     KNTNIAAFTNTEKVHYLVIEDSFPNGRPKLEAAGVIMTDRETVDKADIMKVTTCLNPL
                     HTALAITGCLLGYKSIQAEMQDDDLVGLIKGIGYVEGLPVVESPGVIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGKNFVPSPDPLLVELQEKFSVLKLGEQDPAKIHCAVQEILENKEIFGLDLYQ
                     VEIGKKIEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            26202..27281
                     /gene="uxuA"
                     /locus_tag="L7C88_000925"
     CDS             26202..27281
                     /gene="uxuA"
                     /locus_tag="L7C88_000925"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBP9557773.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKALKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYHLDDGSSTLAYISKNIPTDPEEIIRKVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEAKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLEWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            27355..28782
                     /gene="uxaC"
                     /locus_tag="L7C88_000926"
     CDS             27355..28782
                     /gene="uxaC"
                     /locus_tag="L7C88_000926"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBP9557774.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAEHQPIIDYHCHLDPACLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGAGNDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLKMMDVKAICTTDD
                     PTDDLRYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQAAGIPIKNFNGL
                     KQALSQRVDYFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIESRK"
     gene            28866..29513
                     /locus_tag="L7C88_000927"
     CDS             28866..29513
                     /locus_tag="L7C88_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBP9557775.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINAITAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVEIIKLFPGSAFGPSVVKTYQAPLPYVNIMP
                     TGGVSLDNLEEWFEAGVVAVGVGGNLLAPVEKGDFEEVTRIASKYIDKFYEIKNY"
     gene            29642..31018
                     /locus_tag="L7C88_000928"
     CDS             29642..31018
                     /locus_tag="L7C88_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9557776.1"
                     /translation="MERKFGLRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     TVGTLFLVARFIDAVTDITMGRIVDGSKPSKTGKFKPWILRMSGPVALASFLMYQTSM
                     ASASMSIKVIYMYVTYILWGSIFYTSINIPYGSMASAITSVAEERTALSTFRSIGATL
                     AGMFIGVLTPIFIYTRDSSGAQIVRGGSTFTIVAGVFSVCAVICYVICYKLTVERVKS
                     DESQLKVSLLKSLKGLAKNRALLSIIAAAIFLLLAQLLTMSMNNYVFPDYYNNAQGIV
                     LMNFINPILMLVLVSPVSLIFSKKYGKKELASVGMFFSAIVYLLLFLIKPSNMYVFLV
                     LTSVGYMGLGIFNTVIWANITDVIDDQEVKSGQREDGTIYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLAKVQSGEVLQKLYNSSTLIPAVCFFVVGLILFFVYPLSKEKVLENY
                     NLLNQKHN"
     gene            31029..31823
                     /locus_tag="L7C88_000929"
     CDS             31029..31823
                     /locus_tag="L7C88_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBP9557777.1"
                     /translation="MNSWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKSLEKNDVPSINRLKHWVSVTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNRQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAIQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDILFKCLSGEYIDIEQKYIDTFWKNLTNK"
     gene            31836..33602
                     /locus_tag="L7C88_000930"
     CDS             31836..33602
                     /locus_tag="L7C88_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBP9557778.1"
                     /translation="MTIKVDLRKKPYHLDEDAISWIEETIDAMTLEEKIGQLFVNMGS
                     SRDKNYLSSMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQSPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLSTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNLDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYYKG
                     IISEERLRDALRRILGLKAKLGLHKKEKNKILLPKQEAMEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKDLTEKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGISPIDAYCGLKDTFI"
     gene            33630..35438
                     /gene="uidA"
                     /locus_tag="L7C88_000931"
     CDS             33630..35438
                     /gene="uidA"
                     /locus_tag="L7C88_000931"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBP9557779.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPMVEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVILPKKLLEERLVLRFGSATHEAKVFLNG
                     KLINQHKGGFTPFESEINQFIKDGSNRITVAVNNVIDDSTLPVGILKETIQEDGDIKK
                     ENLVNFDFFNYAGINRPVKLYTTPKDYIKDVTINTKIIDSDANVEFNIDTEWTGEILI
                     AIYDEEAQLIAEAKGKEGVIQLKNPTLWEPLNAYLYSMKVSLINENKVIDTYTEEFGI
                     RSIQVSNGKFLINNKPFYFKGFGKHEDTYINGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHDTWKEIRTENAHKM
                     AIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDICKVGDIVDVLCLNRYYGWYVSGGDLKHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGLHDTVPTMFTEEYQVGYYEANHEVIDKCDNFVGEQVWNFADFETSQGILR
                     VQGNKKGIFTRDRKPKMIAHYLKKRWSSIPNFSYKK"
     gene            35610..36011
                     /locus_tag="L7C88_000932"
     CDS             35610..36011
                     /locus_tag="L7C88_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBP9557780.1"
                     /translation="MQQNYNEKSIQHQFDAYCKKVLRNETKSIRKRNINITDNEEPLT
                     NSNEGKYSQTHFDEQDVYFLFGMEILISDQKLSAAIDHLSEIRRKVILLYYFAGFNDT
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            36005..36250
                     /locus_tag="L7C88_000933"
     CDS             36005..36250
                     /locus_tag="L7C88_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557781.1"
                     /translation="MVDNPKKRQYPLVPLSIIQSALEEDPISIKMILKHYHSYIAKLC
                     LTNGFNEAGQFITYVDEYMLRQLEIKLIEAILKFKIN"
     gene            complement(36574..36795)
                     /locus_tag="L7C88_000934"
     CDS             complement(36574..36795)
                     /locus_tag="L7C88_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557782.1"
                     /translation="MRNEIANITIIRETLQNHTANEISKHTGLNLSTIKKLKSGERSI
                     EKLNLHDAICLTEFGLKNNRKNVEINIWK"
     gene            complement(36957..37029)
                     /locus_tag="L7C88_000935"
     tRNA            complement(36957..37029)
                     /locus_tag="L7C88_000935"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(36994..36996),aa:Lys,seq:ctt)
BASE COUNT        13180 a         5196 c         7391 g        11340 t
ORIGIN      
        1 gagggggcaa gtgtggttgt ccacgaagta gtgattgtgg acaaaatacc gaaattattg
       61 ttagaacggt atggcatttc tcatgagtaa tgcaaaattt aatccacaag cgttccaaac
      121 taagccaccg aaacaacaga aggaaaagaa acaaaagaaa cgttttttgt tccaaaaaaa
      181 gaaaacagaa ccgtcagatc gaatgatcca attttcgcaa aaaagtgcca tgagtgtatt
      241 ttcaggcgct tttttttgtt tgtttctgtt aatgggtgtc gtgctcctcc taaactttgg
      301 acgagtggat acattaacgc gtttagcagt gaaaaaacaa gtcaatccag aaacattgtt
      361 aactgaagtc aaccaaacct tgtcttctac ggaacaattg aagtacgagg gacaacattt
      421 tattgaaagg ttatttactt attcgccaga aaaacgaaac gaatgggagg cttccgtcaa
      481 tcattattta gcacaaggat tggaagcgtc tgatctaggc tttgtaacga cggctaccaa
      541 tcgagtagcg aaagatgttc gctttattaa actagaagaa atcgatttga cacaagcaat
      601 gtatcgccta ttttatgagg ttacttttac agaaggagaa cattggaaaa gcagtcaact
      661 ttcttttcca gtcagttatc aaaacaatgt tttaaaagta cttgatggcg ttcaattttt
      721 gaatctttct gagagtaaga ataccaattc tgtgaactat caggaaaatc gattttattc
      781 ttctgggcaa gcggtcactg aaagcgaaga aatcaagctg gaagcatttg tgaaacggtt
      841 ttttgagtta tatgtcaaaa atgatgaaaa attggcattg atttctaacg aaaaagggtt
      901 agaaggcggc gaattgatca atgtacaact ggatcatgca gtaaaaaata aagaaggaaa
      961 ctactttttg caagggaagt atcgtttcta ttttgagaaa ggaaacgagt tccaatcaaa
     1021 cttttcaatg gaagtaaaaa caagtggcga tagttatttt gttactacgt taaatgaata
     1081 aaatgaactt agaggagaat ggaaatgaaa ctttttgatc ttaaatcgtt atttgatgat
     1141 gtatctggac aagtcatttg gctattggca atcgttgcga ttgttctaat ggttggtgct
     1201 tatgcgaccc aaggctttgc gcgggcagcg tttgccatta ttggcgtctt tattttgata
     1261 atgctcgtct tattgttatc gaatgccgtt gatattggtg aatggctaaa gaacattatc
     1321 tttattaagg atagtgaaga gaacgtgggg gtaacgcaaa tgattgtgcc ctggatacaa
     1381 ttatcataag aaaaagacaa actgcaaaag cgatcagaag attagaactt ctggtcgctt
     1441 ctttttttgt aaaaggaggt agagtgaaca tggaatacaa ctatacaaag gagtttaagc
     1501 accctcacaa aatttacggg attaaaggac aaaaaattcc ctggatttct aatggcattc
     1561 gcatggaaca attagtcata ggtggggtat ttctcttcat tcttttgatc ctatttttga
     1621 ttgcgtatgt gaatcaaatt agtttcttgc agacactgtt tcgaaagtcc tggttgatta
     1681 tgatttttgg gattggtgtt ctcgtttgga cattgttttc aatgaaatgg gacaataaac
     1741 actttttcga gtatttaatt gggcgaacgt cctattatca gaaacggaaa caacgctttg
     1801 aacatgaaat gtatgtgccg tttttccatg aaaaagtgac gtattcccta cacaaatgga
     1861 aggagtgagt cgagtaaatg gcgtttttgt ttcttttggt cgtctttatt atcgggattt
     1921 ggcagttcaa aaagaaaaaa acgaagcttc ctcgattaga atttccgata gacgccatta
     1981 tccgaaattt tgttttgacc aaaaatgatg atgtgtgggt aggctatcaa ctttcttccc
     2041 aagtatttcc tttaaatgac attgattttt tcaagaacta tcttcaagat ggcgaaggca
     2101 tacttggaca tgatgaatat gactatcatt ttatcaatat tccacgtcaa tttaacctag
     2161 atacgcacat tgaagaaacc attcgagatt tggtaaaggg agaatgcgca gatcttggga
     2221 aagtgtactt tgaacaggca ggaaagattt taaaagacga agtgcaatta aacgagtatc
     2281 gaacgtatct gtttgtgcgt ttcactacag aaatgaaagt gtctgatccg atcgaatatt
     2341 ttcaattgct taagcatgtt tttaaaaagt ttatctatcg tattacggga caacgagttc
     2401 ctataagtag tgtgttacca acgtatgaaa cattagaaaa ggagctctat acggaattgt
     2461 ccaattataa gccgatagag cgcttatctg cccaagagat tggacaaatt tattattatt
     2521 ttttccatcg atcagaagaa aaattgcctg aaagacagct tacgccaatg gaaatttgcg
     2581 agggcgtcat ttcgaatgaa gcaggataca ttgcgattga acagttgaat caaacgcatt
     2641 attcgacgtt tttaagtcaa acggacgctc ctttagccat gtatgggagt agctttattc
     2701 aaaatcttca ggatagctta tcttttccaa ttgatacgca tattcgactt cgatttgagc
     2761 attcaaaatc tgatgaacga aaaattaata aaatggctgg acggatttat gaacaagaaa
     2821 aagaatatga gaccgttgac ggcattttag attcagacga tgtattaaat tttggtacag
     2881 aacggttaat ggatgtaaaa gataagctga agcgcaaaga aaaacgattg tgttattcta
     2941 ccgtcacgct ggttgtatct gcttcttcaa aagaagaatt ggaagaacga gtcaaagata
     3001 ttgaatttgc gattgagtct acagatttca aattttatcg atcggtagcg gatcagctaa
     3061 cgttgtttaa tcaatgctta attggaagta cgcaacgttt tcgtagttac gagcaggtcg
     3121 ctacgacagg ttttgtggca gattatggct tggacttaaa gaaagaagta ggaaataaga
     3181 aaggatttcc tttaggacgg attgttattg caaaaaagtt taaatctgcg aaagaagcgt
     3241 tagcgctatc tagtaaacta gtatggtatt atcccaattt aacaaagaaa agtattgaag
     3301 gcgcggaaca taccaatgga aatacgttga ttattggtcc accaggtaaa ggaaaatcgg
     3361 tccttgtaaa atatattttt ttatggctga tgtttttagg tcaaaaaatt ctttatattg
     3421 atccgaaaaa tgaaacccaa aagttctttt taaaggcact tgaaaaattc ggacacatac
     3481 cagagtttgt ggctatgtat gaacgaatta attttatttc gttatcttca gatgaaagct
     3541 gtcgagggat gcttgatcct ctattgtttt taccaaaaga agaggcaatt caaaccgcta
     3601 aaaatgtgtt aggaatgtta ggagaagtag ataccaatcg agaaacagcg agccacaaga
     3661 aaacggtgat ccaagacgcc atcgatgtag tttacaccat gccaggtaag cattcgttaa
     3721 gtcaagttat cgaagaaatt cgaaaaagtg acaaagaact agctaaattg attttagggc
     3781 atagcgttgg tttaggaaag attctcattg ggaatgagca cagtacgccg atacgttttg
     3841 attcacaaat caacgtgtta gggacacaag gaatacgcat tccgacacaa aaagagagtg
     3901 attcgggtcg attaaatagc gaacaacttg caggaatggc aattatggaa gtcattatga
     3961 agtttacgta tatcttttct acaaacaaag aagaagacgc tgcgattatt tatgacgagg
     4021 caaaagggta tgaagatacc gcacaaggaa gctatttgat tgatgatagc ttgcgaaaag
     4081 gacgtgcgaa taatacggat atttaccttg ttgtgcaagc gtttaaagat tacgatcaag
     4141 aagataaaaa agagttaatt tcttacaaat ttgcgtttcg tccgaaacaa aaagaagcac
     4201 gagagaaact attgtccttc tttgatatgg aagtgaattc agccaattta gaaatgatgg
     4261 aacaattaca aacaggaacc tgtttattcc aggatcattt gggaagaaat caaccgattg
     4321 ccattgatgt gttgtttgat agttggttat tggctgtttc ttctactgaa aatcaagatg
     4381 aaaaaattca agcaatgtta gaaaatgaaa aacaacgata aaacaaaaaa gaggtggttt
     4441 ttttgcgaaa aaaatctctg aaatggtgga cgctcctttt attagggggt ctttttttct
     4501 gtctacaagg ggctactgtt tctgccgatc aaatgaatga tggtgcgggt gtcactgaaa
     4561 ccgatcgttc tgaaggagag aatgccaacg ataaagtaga agtaaaagaa gtaacgactg
     4621 atgtggatca attgtataaa aattacaaaa agaattcgtt tgaattgatg accaatgact
     4681 atgagtcaat gaaccttaaa aaaaagctat cgtacaatgt tgcaggagtg atgaaaaatt
     4741 ttgtttggag tggcgtaaaa atgttaggag aattcaatgc ttcaatggtt gaatttctct
     4801 ttgaattaga tattatttcc gccattcgag aacccattca aaacttaaca caaaaaattg
     4861 cggacaatat gttaagtatt gcaggaacta ttggaatcag tttttcggca attatgatgg
     4921 caatcaaata tgctggagag gctcgaatga aacaagcact ccgtgtcttt cttatgacga
     4981 tccttatttt tactgggtta agcgtattaa aagattctgg gacaaataag aatctttttg
     5041 atgttctttt ttctttagat tctacagtgg aaacggcgtt cgtgaaggtc aatccagtgt
     5101 taacacctga agaagaaaca aattatgaaa caaaagaaac agaagaggta acagcggata
     5161 aaaaagtgga aacggcaggc aaattgatgg cggctcgggt cttttatagt aatgtttatg
     5221 aaccatatct gttgttaaat tatggcacaa ccaatgtaga cacaattcgt gagaagaaag
     5281 tcaaatatgc tggaaaagaa tatgatcgaa tcaatctttt attggacaat gatttaggta
     5341 caaaaatagg ggagaaaatt catgacaaag tcacagagta tgaagcagat acactgaaaa
     5401 acaagaacat acaatattac aatagttgga aaaatacagc atttgccttg ttttattttg
     5461 tcgtgaatct gattcaaacc gttgtttatt ttgtcttaag tatgtttcga ttgattattg
     5521 gaactatgca actattgtta gtaccgatgt tgccgttctt acttttttta ggattgtttc
     5581 ttgtcacaat gaatgtgttt ggtaactatg ccaaagtttt tggtattttg acgtttttaa
     5641 aaggaatgac aggttttgca tgtatccttt tttcttcttt tcttagttac gggttccaat
     5701 taagtagtac acaagacgat ccatgggaaa aaattctctt gatcattgtt tatttgtttg
     5761 cgccgttggg aatttatttg ttccgaggct ttttaggcag tctatttact ggaagaatgg
     5821 gtgttcgagg agcgttagct tttgcgggaa atccatttgg ggcagaagca aaattgagaa
     5881 gggaagccaa acaacggttg aaagaacgca aagaagcgag aaaagcacag aaacaaaaag
     5941 aaaaagaaaa cgcacggaag agacaagaac gtcaacgaaa acgtgggggt ggctcagacg
     6001 ttcgtatgcc acaaacggcg aaacaagcca cacgaagtgc ttttcggcgt gaatccgcac
     6061 aacaacctcg tcataaagca ccaaatcgta tggaacgtat ggcacaaaaa gcaagagact
     6121 tgcatgatca agcgaaacaa gcagaagagc aaagtcaaga acgtatgcaa cgaacagcaa
     6181 tggagaaaca ggcaagaaaa acagccgatt tattacaacg agaattgcaa ggcaatccta
     6241 gtctaagaga aagaagtaga aaaggtgcgt ctcgtagtcc gtatcgcaat cagggttctg
     6301 caatggtggt gtcattagcg aatccaaagc aaaaacacaa gtcttatggc cagaagcata
     6361 cgcctagaac agaattgaac gatcgaaaac gtcgtcaggg acaaacaagt cgtcgtcgga
     6421 aggaggcact tactcccgta acaaaaacaa gttcgatgaa aacccggaca gttgcaggac
     6481 aaaaacatgc ggtacaaaaa ccactaagaa aagggaatgt accacgagca acaggttcta
     6541 ccacaccgaa atctgttcga cgtccagagg gggttcggga acatatgtca gcagtcaatc
     6601 gagtaacagc acaaaccaaa gcgccttcaa ccgtatctaa agcatactca accatgaaac
     6661 aaacaaaatc accaaaacaa gcaccgaaga cacggagtga gtttcgagca actcaagcaa
     6721 aaatgaaacg aaaacgagaa aaacaaccga tttatcgaag agaaatgaaa caacgaaaac
     6781 gataggagga aatcgatagt atgatgaatg caccaaaacg accgacacat tttgagcaaa
     6841 tgttttctgt cgatcgcaaa agaaaacaag aaaaagaaac gccaaaaagt cggtttcaac
     6901 aactttattt tatcgtcact ttattaggtg tttgtctata tccatttttt attgtaggca
     6961 gtattccttt agcgattgtc tttatgatag ataaaaaaga gacacgtgca catatttatg
     7021 actttgagta tgagagcttc ttaaaacgaa gaagctctct tttttttatt tttgcgttag
     7081 gttttacgct attaaatcta ttttgtttta tttttgttct tcctagaggg tatttgtcgt
     7141 gttacttatt atttccatta aacttgtttt ctcatgcgtt gcagtttaat ggacaaacga
     7201 tttttgccct ccttttaggt gggacaggtg caggaagttg tttgattgcg tatgcgtctt
     7261 ttattgaaaa aagaaaagtt gtttcaaaga aagaacggca aacagctttg ctaaatagta
     7321 aagaatacaa ggaacgtcgg aagaataaat ttcaggagtc ccaaaaatat acagcagagt
     7381 atcagcaagc gtaccaggta gcaattgtca taaaagacgt tgctttgcgg aataaacaac
     7441 tggcttcatt agccaaagtg attctattag gaacagatga gtatgggctc ccttatgtga
     7501 tgaactttag tgaattgaac caacatgtga ttattccagc gactacaggt tcaggaaaaa
     7561 cgacggtgat ccaattacta gcagaacatg cgtgtaagtt tcgtatcccc gttatcttag
     7621 tcgatgggaa aggagcagga gagactttac aagcgttaaa agaagtggca gaggcataca
     7681 atcgcccgat tgaagtcttt gtggacggtg gcgatttgcg ttataatcct gtaaaaaatg
     7741 gcaatgatat tgccattcga gataaattaa ccaatctagc agaaacagaa agcgtgtatt
     7801 attcgacagc agccaaagcg ttattacagg taacgattca gcttttagac gagttccaaa
     7861 agagccataa aattgaaaga aatctagttt ggttacaaca ttatttattg ccacgaaacg
     7921 tcttacattt gtttgcggat cgtattcagt tgaaaaatcc agatttattt aaagaaaaag
     7981 tggtcgtaga aaagaagaaa accacgaaga aaaaaacgaa aaagaatgaa gcgatggaca
     8041 aaacagaacg tgattttgcc gatgtggaac agttaagtga agagcgaatc gttgaacatg
     8101 atcgtaaaac cgttgactta gaaacgtatt atctattatt aaaagaaaac atttctctca
     8161 tgacagaaat cgagcaaacg ttgtttaaac ggttgtttgt tcgttacgaa cataagaaga
     8221 acccgtttta tttgtatgcg acttctgaga atttacagac caatatcaat atgttattgg
     8281 atagtgagct tggtgaactc tttgatactt ctggaggaaa aagagaatta gatattcaag
     8341 aagttgttaa agaaggaaag attgtttata tctcgttaaa cggattgatt tatagtgagt
     8401 ttattcggac attggctcaa atgcttgtgg gagatattaa tttctttgcg tcagaagtgt
     8461 ataaacaagc aggagaaaca gccaatcgct cgaaagtcct agtaatattt gacgaaccag
     8521 cttcttatct aaatgataac cttatagact tagtcaataa gggacgaggc gctggggtgc
     8581 atgcggcgta tgcccctcaa acgcttgcgg acattgatag aattgatcct gtccttcgaa
     8641 aacagttgat tgggaatgtg aatacgttct ttattgggaa gacaaatgac ccgacagaaa
     8701 ttgattattg ggcagattta atggggacag aagaagacat tgaattaacg gaaatgacga
     8761 cacaagaagc aggttattct gatatgggaa aggttgattg gacaggagaa agaggcacga
     8821 aacgagacgt agaccgcttt aaattcaatc cgaatcgcat tcgagcattg agaacaggcg
     8881 aatttgtggt gtatcgaaca gctgaagacg tccaggaacc accgcgagtc gtctatattc
     8941 ggaaaccaaa tttggagaaa caatatgcga aataagaaag ttattgttag gatacttatt
     9001 gttagtttcc tcttatttgg ttgttttaaa ctgataaaaa ctaacgaaga atcaaatgga
     9061 aaactaatca atagtaattt agaagaagta ctagaacttc aaaaaacgaa tcaatcattt
     9121 tttgtgtatc tagcaagaaa tgattgtaaa aaatgccaag aagttgaatc tttcttggaa
     9181 agatacgaca aaaaattctc taggaatgta tatcgaattg aaacaagaaa agaaccaaga
     9241 caagaagaac ttcaaacttt tttacaacgt taccatgtta aaagtgtccc aagttttctc
     9301 gtgattcatg atagaaacgt caaaaaaatt gagagaaaaa cattcttttt tgaaaagaca
     9361 ttgaatcaat ttcttcctaa tttttagtga aaattgaaag agaatacgtt gaaaaaaaca
     9421 aaaaattgtt atgagttcaa atttttttcg atcgtatttg tttttctttt gaaacaaatt
     9481 cactcatttt ttgagcaaaa atgtttcaaa atttgaacaa aaaccaattg aaaattgaag
     9541 caaatttcac tcgaattgaa tcgattttga gctaaaatca atagaaaaaa taaacgtatt
     9601 ttgtttgaaa tccgtttatt ttttttacgt ttcagtatta gtaaggatta tttgagggtt
     9661 atttagagat tatttaaagg ttatatgtaa taagtggggg gagggctgtc ggcgcttggt
     9721 atgaaaggca ttctccgact tccaggtttt tgaccatttt ctctcaacgt ggaaaaaccg
     9781 ccacttatga gagaaaatgg tcaaaaacct aagcgggaag tctccgaata acataccaag
     9841 cgccgacagc caacagataa agaatacact actaaaaata gtagtagcat aaaatttaaa
     9901 agggaaaaaa tcaaccccta ccccagtctt ggggtctcaa aactaactcc cccctaaccc
     9961 cctctttcag cctcttttga aagaggggga gaatcaaccc cacggccaac gccccagtgt
    10021 tcttggggct gtccagaaca gaaacttgcg agagagtggg ggtaaaacaa gtgtagagga
    10081 aacttgaaga cttgttcgaa cagaaacttg cgagagagcc ggagtaaaac aagtgtagag
    10141 gaaacttgaa gacttgttcg aacagaaact tgcgagagag ttggagtaaa acaagtgtag
    10201 aggaaacttg aagacttgtt cgaacacaaa cttacaagag aggggagtaa agcagttgca
    10261 gaggaatcag gaagatttgt tcgaacagaa acttgcaaga aagcattatt aaattgaagg
    10321 tgatgaaata tgaagtattt attgcatggc tattttattg attattctac tcgcaatagt
    10381 agtactttag cgattctatg tttgcttcat gaattgagag tggttactag aaaacagcta
    10441 tacaaactat tgaattttga cagatcaatt agtaaacaag gagtaacgaa tgctttagtg
    10501 agattatatg aaaaacagtt aatcgatcga aaaaaatatg gaacagaaat gtattattat
    10561 ttgacgaaag agggacatca aagcataggt gggtattata cgttgccgaa agttcctgaa
    10621 tataatttga atcaccattt acaaattaac aattatttga ttaaaggaat ggcattggca
    10681 aaagaccacc cacatttaaa acggattatt tcagaaagac gtaccgtcta tgaaacgaag
    10741 gatttaaatc ctaagacaaa aggaagaaaa ttttttgtgc cagattttat ttttcgtttt
    10801 cgagacaaag aaaatcatga gatcaattgg tcctttgaaa ttgagctaac gttgaaaaca
    10861 cgtcgtcgct accgtgaagc gatttttccg aaatatattc gtgagttgcg aacacgtcct
    10921 gaatcacatt taatttatgt gacacctagt ggcgcaattc aagaagaact tcatgcgttt
    10981 aagcgtattt ttttcaagcg cgaaactgaa aaagatgcga gtcaacaaga attgtttgag
    11041 cggttgcata ttttttcagc tttagagttt gaagagggat taaaagcatt attagagaat
    11101 gatccagcag tcaattggcg gacagtagaa cgagaaaaaa tttatccgaa tggcgctgtt
    11161 caaagtcgtt tgaatttatt tgaagaatca actgaaaatg aggaaaaacc aaaagtgaag
    11221 tttacgcctg aagtattgta aaagagggtg ttcgcttcgc tctttttttg tgccagtttg
    11281 ctggcaccgt tcagacgcaa gcgtctgaac cggctcgttt ttaggaagga ctaacttgtt
    11341 tgatttatcc gttgtcaaag aagtggacgt tcgagagtcc ctaatcgtat agcagtcatt
    11401 cggcgagtat aacctaaaac ataacctgcc aattgccaag ggtaaaatgc acgctgcgcg
    11461 cccttggcaa tcgtcagaac atgttttcga gccggttatg ccgaacgacc gctatacgaa
    11521 aagggcctct aaacagaagt ccactttgat ccttgacaac tgaaacccaa aatcaaacaa
    11581 gcaggccttc gtctaaaaac gagccgaatg aagaccttgg gggttgcacc cccaaacccc
    11641 cgtgcccccg acacactacc gaaaaggtgg gggtgggtgg cgaaaaaatc aaataaaaca
    11701 ttctattcaa gaaaggaaga aacaaccatg acaactaaaa acgagcaact gaaagaacag
    11761 gcaagaaaag agttgcaaga aagaggtttg attattgagg ggagctttga aggagatttt
    11821 gaaacctata ttggttgtta tgcaagaccg ataaacaaac ctacagcctt agacccaatg
    11881 aacgaacaag aagtaaaaga acaagaaaaa catgcagtga atggttttcc gcaagatttc
    11941 actgaatggt atgagtggga aattaacaac gggaagcttg aaaacttctt ataaaagtca
    12001 gatgacgtgc aaagagaatg attctctttg tacggtaaaa atataaagaa agaaggaaaa
    12061 agaaaatggc aaaaaacaca ccttatcaag taggagacat tttttatagt agttggggct
    12121 acgaacaaac gaacgtgact ttttggcaaa ttgtgaagtt aacagaaaaa acagcatggt
    12181 ttcagcctat tcaaaagaaa acggtcgagc attattcgtc catgagtgga aaagttgttc
    12241 caatgaaaga caagtttata gagtatcctt tagcaaaaac taaagacagt attgtaaaaa
    12301 aacgaattga tccagaaacc tatcctgata tgttatgtgg ttatcgtagt tgggacacgt
    12361 ttcatagata taaaaatcaa gctgtttatg aaagtagtta ttattaaggg gatagtttcc
    12421 cctttcaaaa ataataaata gaagaatgga gagaaaaaat catgatgaat tcagtgaatt
    12481 tagtaggacg gttaacaaaa gaagtggatt taaaatacac accaaaaggc aatgcgacag
    12541 gcacatttat tttagctgtt aatcgaaatt atacgaatgc aaacggcgag cgtgaagcag
    12601 attatatccg ctgtgtcatt tggcggaaag ctgcggaaac tttagcaaaa tatactggaa
    12661 aaggaagttt gattggcatt aatggacgtc ttcaaacgag gagctatcag aatcagcaag
    12721 gacagaccat gtatgttacg gaagttctag tgacagattt ctatttgtta gagagtaaag
    12781 aaatcaatga gcaacggtca aaatcaatgg cgaataatca aaataattct tcaattccag
    12841 gaaatgagat tcaaatttca gatagttatt tgccctttta agtgaaaaat aattttgttc
    12901 tatacctgat ttcttcaggt atagaacaaa aaataaatag agatgaggcg attttttatg
    12961 aaaatcattg acagttacga tcaacgaacc atgcaatatt tgggctcgtt tgattataca
    13021 gatgaaaata ttattaatta tgttgcaagt ttacctcctt atcaaagcgt tcgcttggta
    13081 gattttgcaa gtgatgaatt ggtattaaca acgatgggca actttttaga ttatgtcgga
    13141 gacaaaaaat ggttggaaaa aattttgtct aaattgattg cgaaacaaac aggagaagaa
    13201 cccataaatg cgattcaatt gttcaatcga tatgaacaag aaaacaatga ttaaagagga
    13261 gagaaaaaat gaaaagatta aaacgaagta tttttattgt gctagcattg attgattttg
    13321 ttgggacagg ttgtgaagca attgacgttc aaaaagctcc cttatcggaa ataaaacaag
    13381 caataacaaa acaagatgaa gaacaaccgc taaatacaca agtagaaata gtgaatcaaa
    13441 ataaaccgag tttttctgaa gaagattttt cgttagaaaa tggaaccagg caattttttt
    13501 cagatttgga tcgtttaaat cgggtaggtg tagcaagtgc acttttgcat aaaagcagga
    13561 tgccaacaga agaacgagac cgattataca ttaagccaac tggctggaaa caaaagaaaa
    13621 tgaagaatgg cgattatctt tataatcgtt gtcatttgat tggctatcaa cgtgcgacaa
    13681 gtttccccat aagtatgtaa tacgaaacgg gaggattaat cttaagatta atcacaacta
    13741 acctatttga cagttggaat gaaagctatc atgtctgctg aatcaactgg tctgatactc
    13801 ctacatgcaa taaagtctac taggaagtta ttgtatgaag ctaggtaaag gcggcagaac
    13861 aatttctaag tgtggaatca tatgaagttg gatatgccgg gacgctataa attactcagg
    13921 gtgagactgt ttttaattaa actgacgaac ttgcgaatgt acgggtctat aaccgactta
    13981 tattcgaaag atataagatt gcgaatgcaa agaacattat cgaaaagtaa gaatgttggt
    14041 catgaaattc gagatggaag actagcggtg tatctgtcaa gagttggtaa aacatgtttg
    14101 attgattcag atgagagtgg gaatgcgaca aaacgtttta cagaagaaat agagcaacta
    14161 gcagaactga atatacgata tttttaaata ctttagcgga gaataaaaaa atcctctaca
    14221 gaaaactacg gagggcaaca tgtgctattg tttcaacaat acatttttaa tttttaccat
    14281 aacaaaaaag tacttgaaaa aaaacagaaa tatgttaaat taaaaatgaa aaaatggaag
    14341 cggttactta ttcttttgaa tctaagataa aaattcaaaa gaataacata acccaaatat
    14401 gattatactt gagattctaa atatttatcg aaaaggaatt tgttttaagg aaaaatgatt
    14461 ctatggacgg ttattgattt atatttacca aatggctaat aaaatagtat ttcttatatt
    14521 gtatagtttt tgtttttatg tgaaaacatg agcaatagaa ttgtactagt aggataagga
    14581 tggatggaaa atgaaaaaaa ctatttttgt tttagcgatt tttatatgtt ttgggctact
    14641 tttggtaggc tacttgttgt ttaattctaa tgaaatgaga actatttcta cgaatgactt
    14701 gttaaaaaaa agtgaattaa aggataaaaa aaaagaatct cttgccttta taatgtttac
    14761 tcaagaagag tgtgagtatt gtatagcaat aaatccaatc atagatagtg taaataagga
    14821 aactttgaat aagataaaga aatatgatat atctgtagat tttcaatcta aacaaaagtg
    14881 taaaattaag tttgttccga ctattgttgc atatagtaag aataaagaag tggggagaat
    14941 tgacaatgaa ttagataatt tgtatcgaaa aaagcaagat ggttcaattg taatagacaa
    15001 gaaaaaaaca aagacattgc ttatagattg gatgaaaaaa atggataaac aaggagaata
    15061 tttgtatgga gaagattaaa cagacatttc cgttaattaa taaatattgg aataagaaaa
    15121 aaatttttat attttttatt acgtttctgc tgtcatcttt attttctcta attttcccgt
    15181 atctatttag taatgttatt gatttatatt tagagaatga gttatcacag aatattgtgc
    15241 gaatagtaac gattcttata tttcagttat ttttagtctt aattaaagaa gtgtatggat
    15301 atataaaaac tatttatgca tttgaagttg atttatcaat gaaaattgat tttcttaagg
    15361 ttttacaaaa aaaaaatctt tttttttcgc aaacgaagca ttcaggagaa attcaattta
    15421 ggatgttttc ggatatttct actatcgtaa atactatctt tattttttct gttgaattac
    15481 ctgtgatagg cgttttagtt cttgtagcgg tatttattat aagtaaagtg aatcttattt
    15541 ttctgatttt ttcactaata atgatgggag ctatggtgtt acagtataat ttatttcaat
    15601 taccgcttaa gaaaacaatc gagaatacaa aaagtgttaa tcaaagtatt acaggagaat
    15661 tgaatgcaca ttttgatcaa ttagaaatta taagcgcata taattttgag aatatctcta
    15721 ttttaaaatt cgattctaga tttaaagaat tatttaatgt tttcaaaaaa caaaataaat
    15781 tactaacact gggaagctgt ttggcacagg ttattttcca attatggatt ggaggaatat
    15841 ttcttattga tgttatttta ttagctaaag gaacaataag tattactaat tttgtaatag
    15901 tatttatgta cgctaacatg gtccctactt tatggactac tttaattagt attatttgga
    15961 aatggcaaga ctattcagtg tcattaaata gatattacga atattattca aataacaaca
    16021 aagtggctgg cacaaaaaaa ataaataaaa taaattctat tactggtcaa tcattaaatt
    16081 tttcatataa caaaagaaag gtattaagca atataagttt ttcaactgaa atgaataaac
    16141 tattcatgat atcaggagaa aatggaacag ggaaaacaac actgatgaaa ttatttacta
    16201 aacagttgcc ggttagtaat aatcaattat tcgtcaacgg gatagatatt aatatgattg
    16261 ataacgaatc attaagaagg ttaatttcaa tcgcaacaca aataccatat ataattaata
    16321 gctccgtgaa ggagaatatt ttaatgggga ctaaaaacta tgataaaaaa aaattcagta
    16381 aattaataga actattggga ataagtaaat ttatgacgaa attaggtatt actttggacg
    16441 acaatattta tgatgaaaaa atattattat ctggaggaga aaaacaaaaa ataagtttag
    16501 ctagggcgct tattaaatca gcttcagtta ttatattaga tgaaccattt agaaatttag
    16561 ataatgaaac tcgcgataat ttgagggatt atatactaaa tacaaaaaaa gaagtttgtt
    16621 atataattat aactcatgat cacattctag ataatttttt ggattcaaat gatgaaatat
    16681 tatatttaaa taaggagtat gataataatg aatagcaaaa aacttcagat gggtgaaatt
    16741 gttagaggtc ctagtcaaat atctattgat gttacatata aatgtaattt tagatgtaaa
    16801 cattgttaca atgcgagtgg tggagacaat tgttttatgg ataatgagtt gactgatgat
    16861 gaactgttag aacttacaaa agatatatgt aatttaaagc catataatat ttgtttctgt
    16921 ggaggagaaa ctttactgag aaaaaaaata gttttatctt gtgccacttt attaaaagag
    16981 gcaggtattc ctaatattgc tattgttact aatggatcat tagtaactca ggatgttgca
    17041 aaagaattat tcaaagcagg tattaatcga tttcaagtaa gtttagatgg aaaaaatgct
    17101 agtagccatg aagcacttag attatatcca aacagttttg aaaaggcaat taatgctatc
    17161 aaattattta gagaattgtc cgaagaagtg gatgttgctt tttgtcctac tagttttaat
    17221 tacaatcaat tacgagaagt atatcaacta gtaaatactc ttaaagtgaa gtctttaaga
    17281 attcaaccat ttatgcttag tggtagggga atgcaaaata gggaaatagt gccaactgtt
    17341 tctcaatata gaaaactagt ttctgatatt aactatatta aaagaaatga agattatacc
    17401 aagatagatt ggggagatcc aattgatcat atcatccgac acagaacttt attgaaagat
    17461 ttttcgaatt ttgtttctat taggtcagac ggaggattaa tggcatcacc ttacttgcca
    17521 attcaagttg gaaatattaa atgtcacagt ctttctaaat attggcgagc aggactttat
    17581 aaagtttttt ctttagattt agttcaagat atagctactc aagtttcttc aatacaagat
    17641 atgagtaaag aattaaaaaa aggacatatt aaatggctta atgaagatat agaaattgat
    17701 attctcgatg aatacaaaca tgatatttta atttaggttt atcattggaa agtttagata
    17761 aacaaagtac ttttagaaag gagggaaaaa aatgatttct gaacctcaaa tgaataatat
    17821 gtatgaaagc ccaactataa tgggagctgg tgaagctgcg ccaagagctt gttcagcaat
    17881 tatggtgtgt gtgttattag catctgcagg agtaggtatc caagcaggag cggtgtatac
    17941 ttatgctgta gttgctacag tagctgtagc tgcagccgca gtttggaaaa cagtaggatt
    18001 agttggttag gaattaatag gagactaact gtctcctatt gattccaatg attaagctaa
    18061 ggaggaattt taagaaaata atgaaataca ataatttaaa accgaaatta cttaatgaga
    18121 acatagaata tataagagaa gaaaattatg gatatttaac catagttccc aaaaatggaa
    18181 ctgaattgaa agataacgtt ttcaatccaa cagtaagata tatattggct aactgtactg
    18241 gaaaaaacag tgtaaaaaaa atagcgaatg gtttaaaaaa gaagtttcct agtttagaat
    18301 atgaaaaatt ctatcaagat gttgtaggaa ctattaaatt tttcaaacac tataatatta
    18361 ttgatatagg agattatagt atggaagaaa agaaaatata taaaattgaa caaaatttag
    18421 aattagaatt actaaatgaa tcacattatg aagaaattta taattttatc acagatcatc
    18481 ctgaaagtat gtattttcat gaagatattt atcatcaagg aaatagtaaa gaattagaag
    18541 ttgtccttag atataattta ttttcgttta cgagtgaatt ttacttttta agacataaag
    18601 agagaattgt aggaatggtt tctataattg ttaatccatt tcaaaactta tcctacagta
    18661 tagtaaatta cctcatatgt gagcctgcat atactacgac tattttgaca acagtattag
    18721 aaaatattaa cgaagtttca attttagaag taaagaagct agtgattcat ttgctaaatt
    18781 caacagaaga tgaatcacta atcccctatt taaaagattc acattttttt aaagaagcgg
    18841 tactatctaa agaatataga gagcatgatg ttttgagata cgcttacatt tattaaataa
    18901 aatttctgat agtattttaa taattcggat catatcataa gatataggag ggaaaagaag
    18961 tgattttatt gattttgtct ctcgtattac tagttgtatc taatctaatg aaaaataatc
    19021 ctcctacaaa aattaattct ttttatggct ttagaactaa aaagtcaatg aaaaatgaaa
    19081 aaagttggca tttagcacaa aaattgttgg gggatttttc aaaaaaaaaa gttatcccag
    19141 tatttttgat gggtattgtt tttttcagta tagagattta tagtttagct attttaaaaa
    19201 atgaaaattt tttcgttagt gtattaatgg gtgaaagttt aatcctaata ctgattttgt
    19261 gtttaattgt tcatgaagtg aataaacaat tgtgaattaa aaaaataaaa acctagtata
    19321 atcactttaa taaattgttg gtagaaggtg atcaaaatgg gagtaaacga aatgatgaaa
    19381 gtcagattga gtttttaaat gataccttcc tcagaacttc aaaacgaatt caaagattcg
    19441 ttgacaaatc ttgagcaaga tcatttaaaa aaatattttc tcttcatttg acgaaaaatg
    19501 tttagaaatc ttatataagt gaagataaag taattggtgt aattaattgt agagaatagc
    19561 ctttgagcaa ttgaagcgat acaattattt agaaaatgaa cttcctccag catactacat
    19621 gattccttac gggacgatgt taaagaagaa agcaagaaat tttagaagta ttagtagata
    19681 aactaatggg cttttctcaa tttaagggag tagcccaaat gtttatcaaa tatggtgcag
    19741 atacagtagc aaccatgttt acagaagaat atcaagtaga ctattatgaa gtaatagata
    19801 aatgtgtaca ttttgtttat gaaaaagtgt ggaattttat gaattttgcg ataagtgaag
    19861 aaatcttacg agtacaagaa aacagaacag gaatatttac cagagacaga aagcttaatt
    19921 tgattgcgca ttatatacgg aatcgctggt catcaatacc aaattttaat tataaaaaat
    19981 aattatgaac aatcttttat acaatataca caataaatca agtagtattt atgaaaaaag
    20041 acttcaaaaa cagaatgatt ttctatcagt cttagaaatt atagagctaa aaattttggt
    20101 cacgcgtaga aacgcgtttt ttttgttttt ttgatagtaa agaacgtaca aaacaatgag
    20161 aatttaaaag attgtactac cagttttttt accttttcat ttgagtttag agtaagtaaa
    20221 atattactat aaaaacacat attcttgaag aaatcttttt tttgctgtat tcatttagat
    20281 tatgatagag aaaatacgtg agagggggac ctgggatgtg gctatctgat gaaaaaattc
    20341 agtggcgtag ctatcagaag cgtatattga ctaactttgc tacttattta aataacaatt
    20401 cagtccatct agtggctcca ccaggggctg gcaagacctt tttaggaatt gagatgatcc
    20461 gacgtttgga ttgtaaaacc ttaattttgg ttccttccct aatattgaag aaacagtggt
    20521 taacaacaat cgaggaatat ttcttagtaa atccagcaga tagttgctat ctttctgggg
    20581 cgattgaaca tcctagtcat attacagtgg aaacgtatca gaccatttac aaccgactga
    20641 aggaggagcc aacttatggt gatcagctgg agctgttagt tttttgatga agctcatcat
    20701 ttaaaaaaaa gctggggtga attgttgatt gacttgaaga aaaaacaacc gaatctgttg
    20761 acgatttcct tgacagccac gcctccgatt gatagctctc agacggagtg gaagcaatat
    20821 attgagttaa aatggcctga ttgacgaaga aattagcatt cccgagttgg taaaggagga
    20881 ggttctatgt cctcatcagg attttctata tttgattccg gctaatcagg aaactactca
    20941 gcattatttt acctttttag agaaacaaaa tgagctggtg gaagcgttaa tggaaagcca
    21001 agagacggtg gattatttgc tttctttaga atttgttcag catccgcttg agcattcgaa
    21061 ggaaatttat gaaaattttg agctgttcac tagtgcatta atttacttga atcatcataa
    21121 ctatgaattg atacccgaac attggcagct attaggcagt tctaagcagc aaggtaaaaa
    21181 agcttcagtt ccatctttag gtaaaaaaga gctgatcact atttatcagc agatgtttga
    21241 agatcaaccg gaattgccta ttttttatca attgaaaaaa gctggatgat tgtttgatga
    21301 gtcgctgcat ttgtttccag agtatccaga cactgttggt agtcaggcga ttcctgagaa
    21361 aaagcaagca gtttgtcaaa ttttgttaaa agaagaagtt cagctgaagc aagaactgac
    21421 agcggtcatt ttgatggatc gtatttgcaa ggaggtatta gcaggcagtg atggtacctt
    21481 agcttatggc gtggttcctt tgtttgatga agttgttcgt ctattaggta acactcagca
    21541 aatcggtgcc atctgtggag agttcttact gttaccgaaa atgctagtaa ctgttgagct
    21601 ggcagaacta gcgacgggta tgaatgaaca tccttatatg tcgggttatt tttatttgac
    21661 ggtggatgac aaaaaccgcc aagcattgat gcaagcagtt actcgcctat taaccgaaaa
    21721 gaagttgaat attttggtag gaaccgttag tttgctagga gaaggctggg attgtcctgc
    21781 aattaatctg ttgatcttgg ctaatcaagc ttccactttt gtgcaaacac aacaactacg
    21841 agggcggggc ttacgcctag gtgcacaaaa taaagtaacg aacatttggc atttagcgat
    21901 tggattaccg ggagttcctc tgtctgaaca gcctgatttg aaaagaatgc tacggcgttt
    21961 gggcaatatt tcaggtctga cctttgaatc ttcaccaaaa attgagagtg gtggcgatcg
    22021 ctttgcttta ccactggaat atacgaccac cacgatggaa acttatactc agtcgatgtt
    22081 ctatttttct tgtgaacgaa gtcggttgaa agaacaatgg agtactgctt tagctgatgg
    22141 ctggcaccta tctatgccaa tcgtcgttag gaaagtcgat caggtaaagc aaaaacaaga
    22201 aacttcattg ccgatagtag taaaaaatat agagcctcta agcttctggt cagctatatt
    22261 taaaggtaac ttgctggaat atttccaaat tcgtaggcga caaaagctat gggaaaagga
    22321 atgtgcccgc aaaaaaagct tggccatatg cgttcaaacg acgttgcagc gccttggtga
    22381 agttagtgat agaaaagtaa tcgtagcggc tgatcagcag gaatttagat gctatcttga
    22441 gaatgctggc tatcgagaag gacagctttt tactgaagct atgagggagc ttttagcacc
    22501 gctggagaat ccgcggtatt taatcgaagg gaaaaagata gttctgacgg taccagaacg
    22561 ctttggccga aataagcaaa tcgctaacct ttttctaaac gaattaaatc aatcgtcgct
    22621 gcccaaatgt cagttggtgt atactagaaa tcctgaagga cgccaaaagc tagtgactta
    22681 tcgaatgagg caagtcttcc agacccgcga tgaagtaatt attcaaaaaa acatttggac
    22741 gtaagttgat gaaaataaat tttgctagag tagaacaagt ccgagaatta agttgctact
    22801 taactgataa tgccaaggac aggagaatct tttcttgacg actgaaagaa actatttgac
    22861 ttatataacg gtgtgtgatg aatatttgca aggcattctc ttaaaaagta ctcgtaatag
    22921 tttttttgaa aacaaaacag tactttatta ataggactga cagagcgata taagaacatc
    22981 tgcagacaga ggtgaatgct tttctcatga tcgatgaaac aatggtactt cggatattct
    23041 tgcttttagt ttgaaccgtt gtgattttct ttgattccta aaagtagttt tatagaatga
    23101 aaatcaagca tacggaatgc tcctttgatt gtgttgtggt gattcaatct aatggagctt
    23161 ctatatgttt ttttatttgc aaaaagaacc gatagaatat ttttatcagt cttagaaatt
    23221 atagagccaa gaaatttcaa gcacacataa aaacgcgtgt tttatgcatt ttatgagcaa
    23281 aaataactaa agaccattac gtaaaacata ggtaaatcag cattcaatct caaattatgt
    23341 gatcaaatgt tgatattatt tgattataag ttttcttttg ctattatcag tctgcaaata
    23401 aacagattat agagtatgaa tgtagatagt tcaatctttg tttacgacct cacatgtttt
    23461 tttactcaag agaaagtaat ataaagtgac tatatttgac agaactttac ataaaaaaag
    23521 tagttagttt tctgtagtaa tcagaaatgt aaataaatta aaaaaaagaa atttagcagt
    23581 tatatatttt taaaatattt tgggtgagta gtcaatacaa cattttgttc atcaagcatt
    23641 aaatgaagat gcaaggatgt taagaagtta gcttcttcag ggtcttgcat ggtcaaggct
    23701 ttaaatagtt gatgatgttg ttccataatt ttttcccatt ttaatccttc cgtttttact
    23761 cgtaaccaac gaaatcgttc caagtgcgta ttattatctt ccaaccattg ccatacttct
    23821 tcccgttctg caatttcaaa acaagcttta tgaaataaat tatcattatg aaaaaaacta
    23881 cgagcattct tttgactaac agctttttct tgttctgcaa ttatagtttc taaaacttgt
    23941 ttcttttgat tattcatctt ggcacaacac tctagcataa tttgtcgttc taaatgttct
    24001 ctgacaaaac gagcattttt tgctaaatct aagtcgatta atgagatata atttccactt
    24061 tgaggaattg tatcaacaag tccttgatga cggagttgaa tcaatgcttc acgtattgga
    24121 gtacgaccga tagaaagcgt ttcttccaat tttttttctg atactttttt tccaggttct
    24181 aagtcagcgt agataatttg ctgacgaata gattgataag cttgattttg gagactagtt
    24241 ttaattgtca tatttaatcc ctctcaaaat ttcatttttg aatttgatat tttagttcta
    24301 tgctcgttat ataatatcaa atttcaaagt aacatactag ctattaaaaa aacaaaaaat
    24361 actcaaataa gatcaaagag aaattaagct ttaatttaag ttagttctaa aaaatatata
    24421 ttggtgtgct tttactaaaa aaagacacaa taattctgac atggtagaaa aaagaatatt
    24481 tttagttttt tcttattgac agcgattaca ttcgatttta tactacaatt gtaacggaaa
    24541 ctaacatatc agtatggagg ggtaaatatg gttttgatta aagactggca agattctatc
    24601 gaaggattga acaaaatgca agttcaacta ccgtatttta atgtcgaagc ggtcaaacaa
    24661 gaaggtcaga aacatccagt gtggcttcat tttggtggag gaaatcttta tcgaggattt
    24721 catgcagaaa ttgctcaatg cttagcagat caaaatgaat tagaatccgg agtagttgtg
    24781 tgtgagacat ttgatgaaga agtagtagaa aaagcttatc atgactacaa caatgatatt
    24841 ttggagattg ttatgggtga agatggtgaa ctcaaaaaaa gacttttagc agtaacagct
    24901 gatagtttat attgcaatcc aaagaatata acggactatc aaagagtggt taaatatttt
    24961 gaagatccta cattacagtt tacaacgttt actattactg aaaaaggata cagtttaaaa
    25021 gattctaaag gacaattttt ttcggtagtg gaagcagata taaaatctgg acctaccaat
    25081 cctcaacata cgatgagtat tgtgacatcc ttgttgtata gcaggtttaa tgctggagag
    25141 ttaccgattg cgatggtttc tactgataat ttctcacaga atggtcaacg ttttcaagat
    25201 agcattttta tgattgcaga agcttggcaa aaaaaaggat acgtttctga aaaatttatt
    25261 gcttatttaa aggataaaga aaaagtgact tttccttgga gtatgattga tagaattacg
    25321 ccaaatcctt cggaaagtgt caaaatggat ttattgaagg cgggtttcga agacttagat
    25381 ataattcata ctgcgaaaaa taccaatatc gctgctttta ccaatactga aaaagtccat
    25441 tatctagtca ttgaagatag ttttccaaat ggtcgaccta aactggaagc ggctggtgtg
    25501 attatgacag atagagaaac agttgataaa gcagatatca tgaaggttac gacatgttta
    25561 aatccgctcc atacggcatt agcaataaca ggttgtttgt tggggtataa atcaattcag
    25621 gcagaaatgc aagatgatga tttggttggc ttaattaaag ggataggtta tgtagaaggc
    25681 ttaccagtag ttgaaagtcc aggcgttatt gatccaaaac aatttattga tgaagtaatc
    25741 aataaacgtt tgcctaatcc ctatattcca gatacaccgc aacgaattgc aacagatact
    25801 tctcaaaaag tagcgattcg ctatggtgaa acaattaaaa agtatgtcga aaaagacgga
    25861 aatgcagaaa atctaacatt tattcctatc gctattgctg cttggttacg ttatttattg
    25921 gcagtcgatg atcaaggaaa aaattttgtg ccaagtcctg atcctttatt ggtagagttg
    25981 caggaaaaat tctcagtatt gaaattaggt gaacaagatc ctgcaaagat tcattgtgcg
    26041 gtacaggaaa tcttagaaaa taaggaaata tttggtttag atttatatca agttgagata
    26101 ggaaagaaaa ttgaaaaaat cttttgcgaa atgctagtag gtcctcaagc agttcgtaaa
    26161 acaatcaata aatatataac agaagttgga ggaaagtaac tatggaaatg acttttagat
    26221 ggtatggggc aaatgaagaa aaaatctcac tacaagaaat tcgtcagatc ccagcaatga
    26281 aaggaattgt tggaacatta atggatatac cagccggaga ggtctggccg agagaacgaa
    26341 ttaaagcttt aaaagatgaa gtcgaagcca atggccttac cttgaaagtt attgagagtg
    26401 ttaatgttca tgatgatatc aaaattggtt tgccaacacg agatcaatac atcgagaatt
    26461 ataaacagac gattcgcaat ttggcagaat ttgggattga ggttatctgt tataatttta
    26521 tgccagtctt tgattgggta aaatcagatt tggattatca tttagatgat gggtcttcta
    26581 cgttagccta tatttcaaaa aatattccta ctgatccaga ggaaattatt agaaaagtag
    26641 aaaattctac taataatttt gaattgccgg gttgggaacc tcatcggtta tcacaaatca
    26701 agcaattatt agaagcctat aaagaagttg atgaagcgaa attgcgagag aactttgcat
    26761 attttctcaa agcaattatc ccgacatgtg aagaagttgg gattaaaatg gcagttcatc
    26821 cagatgatcc accatattct attttcggat tacctcgtat tgttaaaaat cgtgacgatt
    26881 tagaatggtt gtgtaatgta gtggattctc cttctaatgg tattacgtta tgtactggaa
    26941 gtattgcaga acgaccagat aatgatgtct atgaaattct atctgaattt tgtcaacggg
    27001 atcggattcc ttttgcacat gttcgtaata tcaaatattt aagtgataat ggactcgatt
    27061 tttatgaagc gccgcataaa tcagaatatg gttctctaga tatgtataag atattaaaaa
    27121 caatgtacga taatggattt aatggctata ttcgtccaga tcatggtcgg atgatttggg
    27181 gagaaaccgg tagacctggt tatgggttat atgaccgagc tctaggtgca gtttatttaa
    27241 atggtatttg ggaagcgctt gaaaaggggg cgagtaaata attatataat ggagtctatt
    27301 tagaagaaaa attttctctt ctaaaaacta agggaaggaa aggagtgctt aaatatgttt
    27361 ttagataaga actttttatt agagaatgaa atagctaaaa gactttttca taaatttgca
    27421 gaacaccaac caatcatcga ttatcattgt catttagacc cagcatgttt gctagaaaat
    27481 aagcaataca agaatttgac tcaggtatgg ttaaatgata aaggagctgg agatcattat
    27541 aaatggcgat tgatgcgagc taatgggata gaagaagagt tgatcagtgg tgcaggtaat
    27601 gattatgaaa aatttttagc ttttgtaaaa acagtggaga aggcgccagg taatcctatt
    27661 tttgaatggt ctcatttgga attacaacgt tactttgata ttgatttgac aatttctgag
    27721 aagaatgcac cagaaatttg gcgacgtgcc aacgaaaaaa tccaaacgga ttcctatcgc
    27781 ccaaaagaat tgctgaagat gatggatgtg aaagccattt gtacaacgga tgatcctaca
    27841 gatgacttgc gatatcatac tgagctttct aaacaggata attctttcaa ggtattacct
    27901 actttccgtc cagataaggt ctggagtatc aaatcatcag gattttcgaa ctatatttta
    27961 aaacttagtc aagcagcggg tataccaatc aaaaacttta atgggttgaa gcaggcattg
    28021 agccaacgag tggattattt tcatcaaatt ggctgtcgat tagcagatca cggtttgaat
    28081 acttattttt atgaaatagc agatgaaaaa atactcgaca atctgttaat aaaagcttta
    28141 gcaggaaaaa cggatttcca tttatcagaa attgcacaat ttgttacagg tattcaatta
    28201 catttgatgt ctgagtatac aagatatggt tggacgatgc aaatgcattt aaatgcttta
    28261 agaaataatt caagtatatt aaaggaacaa attggagtag atgtcggtgg tgattcgatg
    28321 ggggatcaag ctagtttgac acaaaatgtt gtagcattgt tcgacactgc tgaaaagagt
    28381 gggtgcttac caaaaacaat tttatattca ttaaatccaa ccgattggct tccactagca
    28441 acagcaatgc aaagcttcca agggggtatg attcaaaaaa tccaattggg atgtgcttgg
    28501 tggttcaatg atacagctga aggaatgcgt caacagttga ctacgatggc gcaacaaagt
    28561 ttgttgtcga attttacagg tatgttgact gattctcgaa gttttctaag ctatcctcgc
    28621 catgagtatt tccgtcgagt attatgtcaa ttactaagcg agtgggttaa agcaggtcga
    28681 attccagatg atgaaatgta tcttagtcag atagtggaga atatttgtta tcgtaatgcg
    28741 tataattatt ttaatttttt tgaaatcgaa agtagaaaat aatacaaaaa ataaaagctt
    28801 aaatttattt attgtaagtt agtacaacta gctagagtat gtatccataa aagaaggaga
    28861 tagatatgaa aaaagtagaa attttaagta agttagaagc ggctggagtc attgcggttg
    28921 tacgtggaaa aaataaagat gaggccatta aagcaataaa tgcaattact gcgggtggaa
    28981 ttaaagggat tgaactaact tttacagttc cgaatgctga agaaataatc aaagaaattg
    29041 ctaaaaaata tgctgatcaa aaagatgtaa taattggagc cggtacagtt ttagatgcgt
    29101 ttactgctcg tattgcaatt atggctggag cagaatatat cgtaagtcca tcttttgatc
    29161 gacaaacagc agagatttgt aatttatatc aaattcctta tttaccaggt tgtatgacaa
    29221 ttactgagat aaaggaggca cttaccgctg gagtagaaat cattaaacta tttccaggtt
    29281 ctgcttttgg tccatctgtt gtaaaaacgt atcaagctcc attaccatat gtaaatataa
    29341 tgcctactgg cggagtaagt ctagataact tagaagagtg gtttgaagca ggcgttgttg
    29401 cagttggtgt aggtgggaat ttgttggctc ctgttgaaaa aggtgatttt gaagaagtaa
    29461 ctcgaatagc tagtaaatat atagataagt tttatgagat aaagaattat taggagaaaa
    29521 aataaataat actataaaat gtaaaaaata aatactaact ctttatactt cagagtatag
    29581 tacgtaagtt ggcagttcaa cagaatgaaa acgcttaaca ataggaagga gcgcaaatta
    29641 tatggaaaga aaatttggtc taagagacaa aataggatat atgtttggag attttgggaa
    29701 tgatttcact ttcatttttg ctagttcttt tttaatgatt ttttatacaa aagtattggg
    29761 gataagcgga gctaccgtag gaacattatt tttagtagca agatttattg atgcagttac
    29821 agacataaca atggggcgta ttgtggatgg atcaaaacca tctaaaactg gcaaatttaa
    29881 accgtggatt ttacggatga gtggtccagt cgctttagca agttttttaa tgtatcaaac
    29941 atcaatggca tcagcttcta tgagtattaa agttatatat atgtatgtaa catatatact
    30001 atggggaagt attttttata catctattaa tattccttac ggttcaatgg catcagctat
    30061 cacttctgtt gcagaagaaa ggacagcgtt atcaacattt cgtagtatag gagctacctt
    30121 agcaggtatg ttcattggcg tgttaacacc aatttttatt tatacaagag atagttctgg
    30181 agctcaaatt gtacgtggtg gatcaacttt tacaattgtg gcaggagtat tttcagtgtg
    30241 tgcagttatt tgttacgtaa tatgttataa attaactgta gaacgggtta aaagtgatga
    30301 atcgcagtta aaagtttcat tgttgaaatc tttaaaagga ttagctaaaa atagagcgtt
    30361 gctttctata atagctgcag ctattttttt gttgcttgct cagcttttaa caatgagtat
    30421 gaacaattat gtatttccag attattataa taatgcacag ggaatagttt taatgaactt
    30481 tatcaatcct attttgatgt tggtacttgt ttcacctgta agtttaattt tcagtaaaaa
    30541 atacggtaaa aaagaattgg cgtcagtagg gatgttcttc tctgctattg tatatttact
    30601 tttatttttg ataaagccta gtaatatgta tgtattctta gttcttactt ctgttggata
    30661 tatggggtta ggtattttta atacagtcat ttgggcgaat attactgatg taatcgatga
    30721 tcaagaagtg aaatctggcc aaagagaaga tggaactatt tatgcagtat attcttttgc
    30781 ccgaaaaatt ggacaagctt tagctggcgg tgtcggaggt tggactcttt ctataatagg
    30841 gtatgattcg ttagcaaaag tacaaagtgg agaagtttta caaaagctgt ataactcttc
    30901 aacgttgatt ccagcagttt gtttctttgt tgtaggattg attttatttt tcgtatatcc
    30961 attatctaaa gaaaaagtat tagaaaatta taatttgcta aatcaaaaac ataactagga
    31021 gaaaaaacat gaacagttgg atattttgta ttgattcaga tggttgtgtc atggatacaa
    31081 tgacttataa acacaatctc tttttcgggc caattgctgc agagattttt gatgttcatc
    31141 atagggaaaa attcctacag gattggaata atattaattt atattcagag actcgtggaa
    31201 taaacagatt tttaggttta gttaaatcat tagaaaaaaa tgatgtacca tcgattaatc
    31261 gattaaagca ctgggtatct gtaacaaaag aattgtctaa tccatctttg aagagggaaa
    31321 tagaatactc tcagtcagag gatttattaa aagctttaaa atggtcggaa gaagtcaatc
    31381 gacagattag tcaagctaaa ggattagata aacccttttt aagtgctaga gatactataa
    31441 aagctctgaa aaaatatggg aagataatta ttgtaagctc agctaataag gaagctattc
    31501 aagaagaatg ggaaagacat gaattattat ccttagttga tgaactgtgt tgtcaagata
    31561 aaggaaaaaa agaagacatt attcgaagtg taattgaaaa tggttgtgat ttggataaga
    31621 tattaatgat tggtgattct cctggtgatc tagaagctgc aaataagaat aaagttttct
    31681 tttatcctat tttggttaat aaagaaaaag aatcatggga aaacttaaga actgatattt
    31741 tatttaaatg tttatcggga gagtatatag atattgaaca aaaatatata gatacttttt
    31801 ggaaaaatct tactaataag tagaggagaa agaaaatgac tataaaagta gacttacgaa
    31861 aaaaaccata tcatttagat gaagatgcta tttcttggat tgaagagacg attgatgcta
    31921 tgactttaga agaaaaaata ggtcaattat ttgttaatat gggatctagt cgtgataaaa
    31981 attacttaag tagtatggtc aatcagtacc atattggagc tgtacgatat aatccaggaa
    32041 ctgctgatga ggtatatgat caaaactata tcctacaaac agaaagcaaa attcctttat
    32101 taattgctgc taatacagaa gcaggtggta acggagcttg tacagatggt accgaagttg
    32161 gtgtagaagt aaaaattggt gcaacaaatg atgcgaaata tgcttatgaa ttagggagag
    32221 tttctggaat tgaagcatcg gctattggat gtaactggag ttttgctcct attgtagata
    32281 ttaatagaaa ttggagaaat cctatcattt ctagtcgatc ttttggacaa agccctgata
    32341 aagttttaga acttagttta gcttatatga aaggtattca agagagtgga attttgcctg
    32401 cagctaaaca tttccctggt gacggtattg acgaacgaga tcaacatcta tcttttagta
    32461 ttaatagttt aagtacagaa gaatgggata attcttttgg aaaagtatac tcaggcttaa
    32521 tagaagctgg attaccttca attatggcag gtcatatcca tatgccagct tattcaaaac
    32581 attttaatct tgatctgaaa gatgaagatt tacttcctgc aactttatca aaagaattaa
    32641 tcactgactt acttagagga aaactcgggt ttaatggatt agtagttact gatgctagtc
    32701 atatgttagg aatgactggg gcaatgaaac ggtcagaatt attgcccact tctattgcgg
    32761 ctggatgtga tctattccta ttttttaatg atccagatga agactttaat tatatgatgg
    32821 aaggttatta caaaggaatt atttcagaag agcgtttacg tgatgcatta agaagaattt
    32881 taggcttaaa ggctaaacta ggtttgcata aaaaagaaaa gaataaaatt ttgttaccga
    32941 aacaagaagc tatggaaaaa attggtttaa ttgaaaataa atcaattttt aaagaggtag
    33001 ctgatcaagc aattacacta gttaaagata aacaagatat ttggcctatt gtaccagaaa
    33061 aatataaaag gattttactg gtagatgtac atggggtaaa aggtgggttt ggtgaagtag
    33121 ttgctggaaa tagacctcag gccattgatt tattgaaaca gattttgtca gcaaaaggat
    33181 ttgaagttga aaaatacatt tcacctgaag aagaattgaa aggattatcg caagaagaaa
    33241 aaattaaaaa tatagctgga atatatgctg ctaagagacc aatcaaagat ttaactgaaa
    33301 aatatgactt gattattaat atagctaatg ttaacccagg tacagttcaa agaattgttt
    33361 ggccagcaag taaaggtact ccggatattc cattttatat tcatgaaatt ccaacaattt
    33421 ttgtatctgt acagtgtccg tttcatttag ctgatgtgcc tcaagtaaaa acttatatca
    33481 atacttatga tggaaaacaa gaaactttag aaatattagt ggacaaacta atgggccttt
    33541 ctgaatttaa gggaataagt ccaatagatg cttattgtgg gttaaaggat acatttattt
    33601 aatatttaaa ttatatagga gtgatttaca tgttatatcc cattatgaca gagacgaggc
    33661 aagtaattga tttaagcggt ctttggagat ttaagttaga tacaaatgat gacttacaag
    33721 aagaacttgc tttagaacca atggttgaaa aagagagtta tccaatttca gttccttctt
    33781 cttataatga tttatttgaa acagagaaca ttagaaatca tgttggatgg gtgtggtatg
    33841 aaaaagaagt gattcttcct aaaaaattat tagaagaaag attagttctt cgttttggat
    33901 ctgcaacaca tgaagcaaaa gtatttttga atggaaaatt gattaatcaa cacaaaggag
    33961 ggtttacgcc atttgaatca gaaattaatc agtttataaa agatggaagt aacagaatta
    34021 cagtggctgt aaacaatgtt attgacgata gcactttacc tgtagggatt ttgaaagaaa
    34081 cgatacagga agatggagac ataaaaaaag aaaatttggt taattttgac tttttcaatt
    34141 atgcaggcat taatagaccc gttaaattgt atacaactcc gaaagactat ataaaggatg
    34201 tcactattaa tacaaaaata attgattcag atgcaaatgt agaatttaat atcgatacag
    34261 aatggaccgg agaaattcta atagcaatct atgacgaaga agctcaactt atagcagaag
    34321 ctaaggggaa agaaggagtg attcaactta agaacccaac actttgggag cctctaaatg
    34381 cttacttata tagtatgaaa gttagtttaa ttaacgaaaa taaagtgatt gatacgtaca
    34441 cagaagaatt tggcattcgt agtattcagg tttcgaatgg gaagtttttg attaataata
    34501 aaccttttta ctttaaggga tttgggaagc atgaggacac gtatattaat ggtcgtggtt
    34561 tgaatgaagc agtaaatatc aaagatttta atttaatgaa atggatcggt gctaattcat
    34621 ttaggacttc acattatcct tattcagaag aaattatgcg cttagcagat cgagaaggta
    34681 ttgtagttat tgatgaagta cctgcagtag gattacattt gaatttcatg gctactttat
    34741 tagatgacaa cgtagaaaaa catgatactt ggaaagaaat acggacagaa aatgctcaca
    34801 aaatggcgat taaggaattg atagaacgcg acaagaacca tccgagtgtc gtaatgtggt
    34861 ctattgcaaa tgaaccagat tcggattctg aaggcgctaa agaatatttt gaacctttag
    34921 ttgaattgac taaagaactt gaccctcaga agagacctgt aacaatcgtt acttacttaa
    34981 agtcaacacc agatatttgt aaagtaggag atattgtcga tgttttatgt ttaaatcgct
    35041 attatggttg gtatgtttca ggtggagacc taaaacatgc aaaatatctg ttgaaaaaag
    35101 agctagatgg atggatggaa agatgtcccg atacgccaat aatgtttaca gaatatggag
    35161 cagatacagt agctggactt catgatacag taccaacaat gtttacagaa gagtatcaag
    35221 tgggttatta cgaagcaaat cacgaagtaa tagataaatg tgacaatttt gttggtgaac
    35281 aagtgtggaa ttttgcagat tttgaaacaa gtcaagggat tttaagagtg caaggaaata
    35341 agaaaggaat ctttactaga gatagaaagc ctaaaatgat tgctcactat ctaaagaaac
    35401 gatggtcatc aataccaaat ttcagttata aaaaataatt taccttttat aaggaatata
    35461 aaaaaggagt ggctgcttaa ttgccaactc ctttttttta taaaaagatt ttctgtttaa
    35521 agaaggatat ttttttctag ttttttcgaa aaaaaggcgc tttctgattg ttgtattagt
    35581 ggaaagggga aaaaaggagc atatttatca tgcaacaaaa ttacaatgag aaatctatac
    35641 aacatcaatt tgatgcctac tgtaaaaaag tattacgaaa cgaaactaag tctattcgaa
    35701 aacgaaacat taacataaca gataatgagg aaccattgac gaattcaaat gaaggtaagt
    35761 actcccaaac tcattttgat gaacaagatg tctatttctt atttggaatg gaaatattaa
    35821 tttcagatca aaagttatcg gcagccattg atcatttatc ggaaataaga agaaaggtta
    35881 tcctacttta ttattttgca ggttttaatg atactgaaat cggtaaaatc ctcaatatga
    35941 gtacaagtgg tatctggtat caacgaaaga aggcagttga acaattaaaa atggggtatg
    36001 acttatggta gacaacccca aaaaacggca gtatccatta gttcctctat ccattatcca
    36061 atctgctcta gaagaagatc caatttcaat caagatgata ctcaaacatt atcatagtta
    36121 tatagctaag ttatgtttga caaatggatt taatgaggcg gggcaattta ttacctatgt
    36181 agatgagtat atgctaagac agctagaaat taaattgata gaagcgatct taaaatttaa
    36241 aattaactaa ctaaaaagtc ccctttccac ttattctgtt taaaagaatc ttctaatagt
    36301 taaaggatta gtagattctt ttaaacagaa aacctattga tcattgaaat ttaaatacat
    36361 tctatcagta cgttaacact tcaaggagca tattttagtt gcgccatgat ttcttactgt
    36421 aaagaaggag cgataaacat tctaaaataa tttttatagt caataaaaag cgatgatttg
    36481 aagttgggat aatgatactt ccgtaaggct cgccgtaaac ttggagagag gtgaaattcc
    36541 tatgtgcttt tgacaaaagc agctgattaa gaattatttc catatgttga tttcaacatt
    36601 ttttctatta tttttaagac caaattcagt gaggcaaata gcatcatgta aatttagttt
    36661 ttctattgaa cgttctccac tttttagttt ttttatagta ctcaaattta atcctgtatg
    36721 tttagagatc tcatttgcag tatggttttg taaagtttct cggattattg ttatattagc
    36781 aatttcatta cgcataatta tgttcctttc ttatcaaaaa tatcaatgac tacagtgggc
    36841 ttttagtgaa aaaaaggggt actacagtct cttttgaaaa caaaaaaata cagtatatac
    36901 gttttctaaa tgctaagcac caacgtttac actgtattta agggtttggc acccaatggg
    36961 ctgtgagggg ctcgaacccg cgacccgatg attaagagtc atctgctcta ccaactgagc
    37021 taacagccca aattaatact ttgttattct aacacctaaa ataaaaaagt gcaatactta
    37081 ttatcagaat tgagagtgaa ttttatg
//
LOCUS       DAFTHM010000019        36910 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFTHM010000019 DAFTHM010000000
VERSION     DAFTHM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.019"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            164..1309
                     /locus_tag="L7C88_000936"
     CDS             164..1309
                     /locus_tag="L7C88_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBP9557783.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            1446..1790
                     /locus_tag="L7C88_000937"
     CDS             1446..1790
                     /locus_tag="L7C88_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBP9557784.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            2061..3347
                     /gene="efmA"
                     /locus_tag="L7C88_000938"
     CDS             2061..3347
                     /gene="efmA"
                     /locus_tag="L7C88_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBP9557785.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLTGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(3485..4084)
                     /locus_tag="L7C88_000939"
     CDS             complement(3485..4084)
                     /locus_tag="L7C88_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBP9557786.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            4488..5609
                     /gene="mnmA"
                     /locus_tag="L7C88_000940"
     CDS             4488..5609
                     /gene="mnmA"
                     /locus_tag="L7C88_000940"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBP9557787.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            5855..7276
                     /gene="arcD"
                     /locus_tag="L7C88_000941"
     CDS             5855..7276
                     /gene="arcD"
                     /locus_tag="L7C88_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBP9557788.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            7290..8408
                     /locus_tag="L7C88_000942"
     CDS             7290..8408
                     /locus_tag="L7C88_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBP9557789.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(8468..9760)
                     /locus_tag="L7C88_000943"
     CDS             complement(8468..9760)
                     /locus_tag="L7C88_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBP9557790.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            9892..10470
                     /locus_tag="L7C88_000944"
     CDS             9892..10470
                     /locus_tag="L7C88_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBP9557791.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            10599..10976
                     /locus_tag="L7C88_000945"
     CDS             10599..10976
                     /locus_tag="L7C88_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBP9557792.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            10909..12981
                     /locus_tag="L7C88_000946"
     CDS             10909..12981
                     /locus_tag="L7C88_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBP9557793.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(13192..14139)
                     /locus_tag="L7C88_000947"
     CDS             complement(13192..14139)
                     /locus_tag="L7C88_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBP9557794.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            14385..14849
                     /locus_tag="L7C88_000948"
     CDS             14385..14849
                     /locus_tag="L7C88_000948"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBP9557795.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(14911..15954)
                     /locus_tag="L7C88_000949"
     CDS             complement(14911..15954)
                     /locus_tag="L7C88_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBP9557796.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(16331..17296)
                     /locus_tag="L7C88_000950"
     CDS             complement(16331..17296)
                     /locus_tag="L7C88_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBP9557797.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            17530..18375
                     /locus_tag="L7C88_000951"
     CDS             17530..18375
                     /locus_tag="L7C88_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBP9557798.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            18566..19753
                     /locus_tag="L7C88_000952"
     CDS             18566..19753
                     /locus_tag="L7C88_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBP9557799.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            19759..20115
                     /locus_tag="L7C88_000953"
     CDS             19759..20115
                     /locus_tag="L7C88_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBP9557800.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            20117..20455
                     /locus_tag="L7C88_000954"
     CDS             20117..20455
                     /locus_tag="L7C88_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBP9557801.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    20531..20787
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20850..21884
                     /locus_tag="L7C88_000955"
     CDS             20850..21884
                     /locus_tag="L7C88_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9557802.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            21877..22563
                     /locus_tag="L7C88_000956"
     CDS             21877..22563
                     /locus_tag="L7C88_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557803.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            22587..23435
                     /locus_tag="L7C88_000957"
     CDS             22587..23435
                     /locus_tag="L7C88_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBP9557804.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            23632..24405
                     /gene="sufC"
                     /locus_tag="L7C88_000958"
     CDS             23632..24405
                     /gene="sufC"
                     /locus_tag="L7C88_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBP9557805.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            24418..25704
                     /gene="sufD"
                     /locus_tag="L7C88_000959"
     CDS             24418..25704
                     /gene="sufD"
                     /locus_tag="L7C88_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBP9557806.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            25701..26936
                     /locus_tag="L7C88_000960"
     CDS             25701..26936
                     /locus_tag="L7C88_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBP9557807.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            26923..27393
                     /locus_tag="L7C88_000961"
     CDS             26923..27393
                     /locus_tag="L7C88_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBP9557808.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            27398..28789
                     /gene="sufB"
                     /locus_tag="L7C88_000962"
     CDS             27398..28789
                     /gene="sufB"
                     /locus_tag="L7C88_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBP9557809.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(29858..30523)
                     /locus_tag="L7C88_000963"
     CDS             complement(29858..30523)
                     /locus_tag="L7C88_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557810.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            30703..32685
                     /locus_tag="L7C88_000964"
     CDS             30703..32685
                     /locus_tag="L7C88_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBP9557811.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            32689..33327
                     /locus_tag="L7C88_000965"
     CDS             32689..33327
                     /locus_tag="L7C88_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557812.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            33355..33783
                     /locus_tag="L7C88_000966"
     CDS             33355..33783
                     /locus_tag="L7C88_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557813.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            34240..35151
                     /locus_tag="L7C88_000967"
     CDS             34240..35151
                     /locus_tag="L7C88_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBP9557814.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            35368..35805
                     /locus_tag="L7C88_000968"
     CDS             35368..35805
                     /locus_tag="L7C88_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557815.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            35900..36784
                     /locus_tag="L7C88_000969"
     CDS             35900..36784
                     /locus_tag="L7C88_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBP9557816.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
BASE COUNT        12234 a         6548 c         7723 g        10405 t
ORIGIN      
        1 aagaagttgt gacagaagtg agcagcttca aggagctgcg acaagacttt tgtcacagct
       61 ccttttttct atgcccatga aacgtcctct agacaaaaat gagctcttct ttggtttgtt
      121 cgctatttta tgctagaatg tgcctagcaa taatttggaa gggatgaatg aagtgaaaac
      181 tatttatctg gatcatgcgg caactacccc catgcatcca caagtaattg aagcgatgac
      241 ggcaatcatg caagacacgt ttggaaatcc ttcaagcata catggatttg gtcgccacgc
      301 gcatgaaaaa ttggaaacag caagacaaat cattgcagac agtctgcaag caaaacctca
      361 cgagatcatc tttaacagtg ggggaacaga aggggataat acagctatct tagaaacagc
      421 gttctcgcgt caaaaagaag gcagacatct aatcactaca gctatcgaac atcctgctgt
      481 tcttaatacc atgaaatatt tagagacaaa ggggtttgac gttacatatc tgcctgtaga
      541 tgaaaaaggg aatctgtcga tcgaagaggt caaaaaagcg ttacgagaag atacgatctt
      601 ggtctctgtg atgtacggga acaatgaaat cggaaatttg atgccaatca aagaaatcgg
      661 tgaactttta gcggatcatc cagcttattt ccatacagat gcggtacaag cgtacggaaa
      721 ccaaacgatc catccagaag aattaggaat cgatttatta agtatctctg ctcataaaat
      781 caatgggcca aaaggcgtcg gtttcttata taaacgagac ggagtaaata tccctgcatt
      841 gcttttaggc ggggagcagg aagaaaagcg gcgtgcaggt acagaaaatt tagcagggat
      901 ctggggtatg gcaaaagcag ttgaactgct gtcacctgaa gaacgtgaag cacgtaacaa
      961 caaatataaa ggattccagc aattgattct tgatacatta gaagcaaacg aaatccctta
     1021 tcaagtaaat ggtgatttaa cgaataaact ccctcatgtg ttgaatcttc gcttaattgg
     1081 cgaagcaaat gatttgctac tgatgaagct tgatcttaat ggggtcgcta tttctactgg
     1141 ttcagcttgt acagcaggaa atatcgagcc ttcacacgta ttggaagcaa tgtatggaga
     1201 agatacaccg atactaaaag aatccatccg tatcagcttt ggtttgggaa ataccgaaga
     1261 cgacatccag tatttccttg atcaattagt tcgtgctgtc aaaaaataac tagtgaagtc
     1321 attcttatat gaacagatgt ctgagagaac gccttcattt tttagggaac ttaactgaaa
     1381 aacctagtaa aaatcaggat aaacttttat aataaagaga aactaatttt atcgaggtga
     1441 aaatcatggc atttgaaaca acagcaacgg tactgggcgc accaattagc tatcgtttgc
     1501 atcctgatgc aaaaagatat acattgcgcg ataatggatt tacagaaaca aacggaggca
     1561 attatcaatt gatccgacca ttagatgcca cgccgcaaag caaagaagga ttcaaattaa
     1621 aaatcactgt atcaaaagat attcaaacat tgaaaatgtc gatcactaca gcaaatggat
     1681 tgaaagcagt caatattttc aaagatccaa aacagaaaat gagccaagat aaattttatt
     1741 ttctgatgga tgggatgatt agccgtgggt tattcgaaaa agtcgaatga tctgtggata
     1801 taaaaagaca actagttttg aaacggccta ttgttagatg actaactttg taaggacgac
     1861 gcaaattagt tgtctttttt atttttaaat ttaacacatg ttgttatttt taatattttg
     1921 ctgatttatt gtttctaagt aaagaaattt aaattgaaac gattgttatt tagggaaaaa
     1981 ggtatttttt gaaaaaagaa tcccgtataa tgattgttgt gcaaacgcta tacaaaatga
     2041 aaaagaaaag agggatgttt atggaaaatg aacagtcggt cgttttaacg aattggaaga
     2101 gaaattattt gttcttttta tcgggacagt ttttgtcagg aatcactagt atggtcgtcc
     2161 aatatgcgat catctggtat ttgacaagag aaaccggttc ggcgacaatt ttgagttttg
     2221 ctactttact aggaatgatt cccatggttt tactaagccc atttgtagga ccgctagtgg
     2281 atcgctggga taaaaaagct cttttgattg tcacggatat tattgtagcg attttcgcgc
     2341 ttattttagc agtagtcgga acgatttcag aatccttccc gatttggcta gtttttgtgt
     2401 ctttgtttat gcgttcggtc gcacaaacat tccaaatgcc aacgatccag tcgattatgc
     2461 cgacaatcgt tccatcttct cacataacaa ggacgaatgg acagttagga atggtccaat
     2521 cagcgaattt catcattgcg ccagctctag gtgcggcttt gttttcagtc gttcctgtca
     2581 attaccttat tttattagat gtattggggg cagtttttgg tgtcggctta ttgatttttg
     2641 tgaagatccc aaaagtttct cctgaaatat tggaagttcc gcttactatt tttaaagatg
     2701 caaaatttgg gctgcagcaa ttgatggata ataaagggtt atggtacata acgatcaatg
     2761 gtgcatttgt gatgctgttg ttcatgccag caatcagtct gtatccattg atgacgctag
     2821 attactttgg tggttccgtt ggacaggcgg gagcagtgga agtagtctac gcagtcggaa
     2881 tgctcttagg cggtgcactg atcagtttta taggaacatg gaaagaccga atgaaaccta
     2941 ttattatagc ctacatcatt atgggcctga cgatcggtgc aagcggattg gttccaaacg
     3001 atagtcaagg gttcttgtac tttcttatct tgaatgcagg agcaggttgt gcaacgccat
     3061 atttcaatac actgctgatg gcaatgatcc agcagagtta tgaatcgaat gttttaggtc
     3121 gtgtcttagg gaacttcaac tctttgatga acctgacagg tccaattgga ttattatttg
     3181 caggaccatt agctgatcgt ttaggggtag aaaaaatgtt cttgttttcc ggaatcggga
     3241 ttttattatg cggaatcgtt ttatttttaa cgtcagctgc ccgaaattat gataaagaat
     3301 tacagaaaaa actggtaaaa gaacaccatg agcaaaaaga cgaatagtat ggaatggagt
     3361 tgtgacagaa gtcttgttac aactccattt ctgatcctaa tgttcctgtg gcaataagcc
     3421 tactcaaatg aaaaatatga gtaattatct ttatttgttt aatacttgat atagggcagt
     3481 tttttcacga cctatcgtac ttcctctttg cttcatagat ttctttgatt tgttgctcag
     3541 ataacggagt gccaaatggt agtttttcct ttaagagttc tctttccggt gcgtctacgc
     3601 ctacattgac atcgttctcg ataggtacgc tgtaatgatg gatatgtcca tgaagattgc
     3661 ggatagtgtc gttaggcccg agcaacatcg gataatgagt caagtaatat tgttgatggt
     3721 cgaatttaac gatggcacct acatcataaa aataaaattt gggacttccg tcagtaagcc
     3781 taggatcatt tttttctaaa taacggaaaa aagcgcgact gtcatggttc cctttgatca
     3841 agtggattgt tccttgcagt tgagtgacca gttccaaaat ttctgcattt gctttttcat
     3901 attgcggatg catagcaagg tcgcctagat gataaacatg gtcggtttct tttattactg
     3961 cattccagct agtgatcaac tgttggttca tttcatccac atttgcaaag agccgcggag
     4021 caaagtcgtt ttttcctaat aagcgttcat ggaaaaagtg catatcactg ataaagtaat
     4081 tcatgtatct tttgcctccc ttttttctta gagtaaacaa aatcacttat ctgagcaact
     4141 cataacatct aaaaagaaaa ggttgtaaat gagacgtgca gctttaagcg ataagaagca
     4201 attttgaaaa atagtttttc acaatttata aaattattcc ttattgccga aaggctggcc
     4261 ctttttatga gtatgccaat tttttatatc gaatgctcaa aagatgagtg attttttggt
     4321 tgactatcat gtttgtgtac tgaataggtc cagtagaaca gtatttttac gacttgataa
     4381 ttaagggatg aaattttcag aaatatgacg tataatgtaa aatactgaaa agttgcgacc
     4441 ttcaactcgt agatgtttca gaatctaatt gaaatgatgg tgatatcatg acagacaaca
     4501 gcaaaacacg cgttgtcgta gggatgagcg gcggtgtcga ctcatctgta acagcacttt
     4561 tgttaaagga acaaggatac gacgtgatcg gaatattcat gaaaaattgg gatgacacgg
     4621 acgaaaacgg tgtatgcacg gccacggaag attataagga tgtagcgaaa gtagctgctc
     4681 aaatcgggat tccttattac tctgtgaatt ttgaaaaaga atattgggat cgtgtatttg
     4741 aatatttcct agccgaatac cgcgcaggac gtacacctaa cccagacgtg atgtgcaaca
     4801 aagaaatcaa attcaaagca ttcttggatt atgcaatgga tcttggcgcc gattatgtag
     4861 ctactggaca ttatgcgcaa gtcactcgcg atgaaaacgg cgtggtccac atgcttcgtg
     4921 gagtagacaa taataaagat caaacttact tccttagcca attatcacaa gaacagcttt
     4981 caaaaacgat gttccctcta ggcggcatgg aaaaatcaga agtacgggca attgctgaac
     5041 gcgcaggcct tgcgactgct aagaaaaaag attcaacggg aatctgcttt attggtgaaa
     5101 agaacttcaa acaatttttg agcaactatc tgccagcaaa aaaaggaaat atggtcactc
     5161 ttgatggtga agtcaaagga caacatgctg gcttgatgta ttatacgatt ggtcaacgtc
     5221 aaggactagg gatcggtggc ggaggagatt cgcaagaacc ctggtttgtt gtaggaaaag
     5281 atctagcgac aaacacatta tatgtggggc aagggttcca tcatcctgca ttgtatgcca
     5341 caagcttgga tgcaagtgaa atccacttta cgacgaatga accaatgcca aaagaattca
     5401 agtgtacagc gaaattccgt tatcgtcagc aagacgttcc tgtgacagtt cgcttattgg
     5461 atgataatcg tgcagaagtc gtattcgacg aacctgtacg tgcaatcact cctggacaag
     5521 cagttgtatt ttatgatgga atggaatgtc tgggtggtgg tttgatcgac cacgcatatc
     5581 aagaaacaaa agttttacaa tacgtttaag cgatattaaa tgaatcaaaa cagctatggc
     5641 taacaaaaga aacacctttt cttttggata gcatagctgt ttttttgcaa taaaattaat
     5701 ttttattcat tttatacttg aaatacttgt gtaaaaagtt cataatatcc aataatatga
     5761 ataaagttgc tttttgttaa gcaagagcag ttgcaaaata gaagggaatc ttttgcaagt
     5821 gatttgttca attttataag tgagggtgat ggaaatggaa aagaaatcga cgggtattag
     5881 caaatgggga ctggttgctc tggttgtcag ttcgtcaatc ggaagcggtg tgtttgggat
     5941 cacaagtgat ctggctagtt ctgcagctcc agggccagcg atcctttcat ggataatcgt
     6001 tgggattggt attttagctt tggtattatc gctgaatcat ttaggagaaa agcgtccaga
     6061 tctagatggt ggtattttcg gttacgcgga agcttcattt ggtaaattag gtggcttcat
     6121 cagtggttgg ggttactggt tgtctgcgtg gctgggaaat gttgcttttg caacgatgct
     6181 gatgagcgcc atgggagaat ttttcccgat attcaaaggt ggacaaaatg ttccttctat
     6241 tttatttgca agtattttta tttggggtct gactttatta gtaaacaatg gagttgaagg
     6301 agcgagcgtc atcaatacaa tcgtgacgat ctgtaaatta gtgccattat tcctattttt
     6361 aatatttgta tttatcgcat ttaaagtgaa tatattcact gctgattttt ggggtaacgt
     6421 atctgataat ctagtgaatg gaacagggca gcaaggaacg atctggttgc agattaaagg
     6481 ttgtttgatg gttatgatgt gggtctttgt agggatcgaa ggcgcaagtg ttttagccaa
     6541 ccgcgcgaag aaacgttcag aagcccagca agcatcgatc attggtctgc tttgtttatt
     6601 gtttatctat atccttgctt cgatcttgcc atacggcgtc ttatctcaag aagagttagc
     6661 aactatttca caacctgcta tggcaaatat tttaaaagga atcgtgggaa attggggagc
     6721 agcgctgatc aatatcggct tgattatttc gatcattggt tcttggttgt cttggacgat
     6781 gctcccagca gaaacaacga tgttgatggc tcgagacggt ctgttgccga aaggttgggg
     6841 aaaaacgaat aaaaaaaatg ccccaactta ttcgttagtt gttactgcaa tcttgactaa
     6901 tctattctta ttgactttct tagttactga ttatgcctat caatttgcct attctttatg
     6961 tacagcggca attttgattt gttatctact tgtcgggatc tatcaagtcc agttttcttt
     7021 aaaagaagga atcaaaaaac aagtagtgat cggtgggatt gctgtagttt ttgaattgat
     7081 gggcatcatt ttagcaggat tttcttatgt ccttttatgt agtattgcct atcttcctgg
     7141 tttttgcttc tactggatcg cttgtcgtga aaccaaacat caaattacgg gaaaagaaaa
     7201 agtaatgatt gggctgattt gtgtggccgc actgctttca atcgggttgc ttgctgtagg
     7261 ctggatcaag atataagggg gaaagaaaca tgaaaatcgc aaatttcggt gtagaagaat
     7321 ggctaaataa atgggaaaag aaagcggtat atgatattgc acaaagctcg atcgaagcat
     7381 tgacattaga cgaactcgtt ggcttagatg ggactagcgt aagtaaattt ttcgaaaaac
     7441 gcaaaaacga accattggac tatggctgga tcgaaggatc agatgttttc aaacaagaag
     7501 tcgcttctct ttatcaaacc gtcgatccgg aaaacatctt acaaacgaat ggagcgactg
     7561 gtgctaatct tttagctcta tacgcgttag tggaagcagg agaccatgtt gtttcgatgc
     7621 ttcctactta tcagcaatta tatgacatcc ccaaatcttt aggtgccgct gttgactttg
     7681 ttcatttgaa ggaagaagaa gattggcagt ttgatttaga acagctagaa gccttagtca
     7741 aacctgaaac aaaaatcatc tgtttgaata gtgcaaacaa tcctacaggc acattgctag
     7801 atcggaaaac tttagaaaaa atcgcagaaa ttgctcgtac agtagatgca tatgtattga
     7861 tagatgaagt atatgcgcct ttaacggata aaggtgaatt cttgtcgatc gtagatgtct
     7921 atgaaaaagg tatagcaacc aattccctat ccaaaaccta ctccattcca ggtattcgta
     7981 ttggctggac agctactgga cctgagttgg cagaagtttt tcgaaagtat cgagactaca
     8041 cgatgatttg cggcggagtc ctgtcagatg atcttgctgt acatgcattg aagaataaag
     8101 aaaaaatatt ggcgcgaaac aaaaagatca ttacagagaa ccttgtgatt ttaaaacaat
     8161 gggtagccaa tgaaccgaaa gttgaacttg tcgctcccaa ttacgtctct acttctttca
     8221 ttaaattagc catcgaagaa gatgaccaga cattttgtat caatttatta gaagaaacag
     8281 gagtactatt agtaccagga agtgcctttg atttaccgaa gcatgcccga ctaggttact
     8341 gttgtaaaaa agaaaccttg gaaaagggat tattcctctt atctgagttc ttgaaaaaac
     8401 aggcctaaac aaaaacactg caaggacagt ctgtgacaac tgttcaagca gtgtttttca
     8461 tttacgctta ttgtctatga gaaggagagt gccctgaagc tatggagact cctgaagctt
     8521 tttcttctgc agtttcttgc tgatggatct cttgtgtatt gtgtcgtaca agcaagaagt
     8581 tgaccaaaac aagaagagaa gtcgaaagaa agacgccacg ataaccaaat gcactggaaa
     8641 cactggagcc gatcataggc cctactacgt taccagttgc ttggaaagat tggttataac
     8701 tgaagatccg tccagcagct tgatgaggcg aatattttgt gatcaatgct tggacagcag
     8761 ggagcagaca agcatcagag ataccaatca aaaaacgtaa ggcagctaat tgccaaacat
     8821 tcgtgacgaa tgccattggg atataaacca gaatcgcaaa acccaaacca atcgcaagta
     8881 ttctttcact cccaatcttg tcacctaagc gaccaaatct tggagcggct atcaaagtgg
     8941 caatcccagg tatcgaagca atgattccgc tgatcaacgt aacattccca tgtccatgca
     9001 gcaattggcg aatgtacaga ctgatgattg gactaatgga attgttggat gcttggatga
     9061 tcatcgttgt gacgaacata ccgatgacga cgtgtggata tttcaagtct ttgaaaatct
     9121 gtttggcaga aaccatgttt tcttttttca ctgggacaaa tttttcatgg acgaaaaaca
     9181 gactcaacaa gaagacgaaa aataagatga tccctgtaat gaaaaaggta gggcgatagc
     9241 caaacgctga agcagagatc ccgccaagaa gcggtccaag taatgttcct gtaacagaac
     9301 cagttgctaa ggttccaaga acttgaccac ttttttcttt tggcgtccca gttgcgacaa
     9361 gggcagtggc attactgata taaccagaaa aaatcccttg aagcagacgc aatgcgacta
     9421 attgatacac actagtcacg caacccatca aagaaatgac gattgccatt cctaatgaag
     9481 cacgcaacag catcaatttt cttccttttt ggtcggctaa ttttccccac caaggagaga
     9541 taagcgtagt caccaagaaa gtagatgaaa aagtcaatcc gctccaaaag ttcaattgtg
     9601 acgtactata attacctaac gtatctatgt aaagtgacat aaaaggcatg actaaactaa
     9661 atccgatacc agccataaat gttccaaacc ataagacaaa caagttttgt tcccaagttt
     9721 ctcttttcct aaataatttt tcctttattc ttgcagccaa ttagactcct tctttctgaa
     9781 aattttcatc tacagctctt tattataaac tacaatatgt agtttatcaa tgaaagtctc
     9841 ttttttctct ttctttttcg tggtaaactg aaagagtgaa ggatttattt tatgagagga
     9901 aacatggaaa tgaaaaaaag aaatctgtct caagagaaaa tcatcgactg ctttcgagaa
     9961 ctagcagaag agatggatgt tcagcaaata acctttcagc atttagccaa acgcttggat
    10021 atcaaggctc cctcgctgta taaccatttc aaaaatattc gtgatgtcaa aacagcgcta
    10081 acagcgaaac ttctgcagga acttaatgac cagctgcgac gggctcttgt gggaaaaagt
    10141 ggtcaggaag cactgcagat ctatgcagaa acttatcgat cctttgcttt ttcaaatcaa
    10201 gcagtgtatg agttactgat cagtgtaccg cataccaatg aagctgtttt attagatgga
    10261 atccatgaaa cgaatcagat cattttgcag atatttgagg cttttcaatt aacgaaagaa
    10321 gaaaaagttc atcgaagcag ggaacttcgt agtatgatcc acggttatct ttccttacgt
    10381 tttttaggat actttacaaa agaaccaaca atcgatccag aagacagcta tttttggatg
    10441 atcaataact ttatcgctac tttgccttaa acaatcagat tcatttgtaa caattttaag
    10501 atgttcatta aatgaccctt ttataagaga aaattcttgc aactttcttg aaaagtgact
    10561 aagatgagtc tagaaaagct gaaagaagga gcacgagtat gtatcaagta attaccatgt
    10621 tcggggacaa tgagccttgg tggttttttg aagactggga agaagatatt gaagaagaag
    10681 aaacattcga gtctttcgaa gaagcacgac aagcgtacga aaaacaatgg aacgaaatcc
    10741 atcaaaatta tgaatatatc aatgcaaaaa gtaactttct cagcgccttt tggaatgacg
    10801 gagatgagcg ctggtgtgaa gagtgtgacg atgatttaca gcaatacaag ggacttgcgt
    10861 tgttgaaaaa tcatcagccc atcacagtag aaagcagaaa ggaattttat gaaacaacta
    10921 attctagcgg aaaaaccaag cgttgcgaaa gacctaagca aggtgcttgg tgctaatcaa
    10981 aagcacaaaa attattatga aggacccaag gtgatcgtta cttgggccct tggtcattta
    11041 ttaggattga aaatgccgga agatctgaat aaggaatggc agagctggca aatggacacg
    11101 ttgccaatga tccctaaaaa actaggaatc aaaccacttc ctaaaacagg acatcaatta
    11161 aaagcaatca agcagctggc tcagcgaaaa gatgtctcag aagcagtcat tgcgacagat
    11221 gccggaagag aaggggaact tgttgctcgc tggatcttag agtatgtgca tttcaataaa
    11281 ccagtgaagc ggttatggat ctcttctcaa acagataaag caatcaaaac tggattcaag
    11341 caactaagac ctgcgaaaga atatgatgca ttgtatgaat ctgctcttgc ccgggcaaaa
    11401 gcggactggc tggtaggatt gaatgtgacc agagccttaa ctgtgaagta cgcggataat
    11461 ttatcagcag gccgtgtgca gacaccgaca ctagcattag tgagagacca agaaaagaaa
    11521 atcgagcagt tccgtccaca aacgtatttc acgatcacgt tgcaagctgg aaaagaacaa
    11581 gccaaaatgc ttcaaaaaaa tcaatttgct ttaaaaacac aagaagaagc acaaaaactt
    11641 gttcaattga tcagtacaag caaaggaact gtcacagaag tccaagaaaa attaaaaacg
    11701 gaatctgcgc cattgcctta tgatttaaca gagatccaaa gagaagccaa tcaacgctat
    11761 ggctattctg caaagaaaac attaagtctt gtacaaagtt tgtatgagac ccataagatc
    11821 gttacttatc cgcgtacaga cagcaaatat ctgacaaatg acatgaaaag tacgatgaaa
    11881 gaacgattgc aagcagtcag cgactttgct cctgaggtca agcagtattt gaaaaacgga
    11941 gccatcgtcc aacagacaaa agtattccaa gacagtaaag tgaccgatca ccatgcactt
    12001 ttgccaactg aaaacagagc acgttatgaa aaattaagta atgaagagcg aaaaatctat
    12061 caaatgattg tctctcgttt tttaggactg tttgctcaac cccataaagt cagccaaaca
    12121 aaagttacgg ttgaatttgg taaagaacga ttcatttttc ggcaaaatcg tgtcgtccaa
    12181 gcaggatgga aaggcgaaac tgaaactgag acggaaacag tcaaatggga aaaaggaatg
    12241 agaatcaatc ccgatttcgc catcaaaaaa gaactatctg caccgcctaa accattgtca
    12301 gaagcaagct tgcttggtca aatggaaaaa tacagtctgg gaaccccagc tacgcgtgca
    12361 gagattatcg agaaactaat caaatctgaa ctgatggaac gtacccctca aggactgcaa
    12421 gtatctccta aaggtaagca attattagta ttggtaaatc cctctttagt aacaccagat
    12481 ttgacagaaa gctgggaaaa agaccttgaa gctattgctg caggaaagaa acaagcagga
    12541 accttcttga atggaatcga aaaagaaaca aaacgcttgg tgaatgagat caaatcaagc
    12601 aaacaagaat atcaagattt ctcgattacc caaaagaaat gcccagaatg tggggccaat
    12661 ctgcgcgaga aaaacacacg tgacggcaaa atctatgtct gcaccaattc agattgcaac
    12721 taccgcagaa gaaaagatcc aaaagtctct aatcatcgat gcccgcaatg tcaccggaaa
    12781 atggaaatca tcgaaggtaa aaacggtgct tatttccgtt gtaaatacga tggaacgaca
    12841 gaaaaattgc ttgataaaaa agagcagaag aagaaaatga ccaaacatga agaacgacgc
    12901 ttgctgaaaa aatatgcaca agcagaagaa ccagaagaaa gcccattagc agcagcacta
    12961 aaagcagcaa tgaagaagta ataagatatg aaagaggttg tgatagaagt ggtcagcttc
    13021 aagaaataag aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ttcggcttat
    13081 ttccgaagaa gctacttctg gaacaccatt tattcggaaa aaaggactgt gacaagactt
    13141 ttgtcacagt cctttttcat ttaaaaaaat gtttacttca tttgacgtat attattggtg
    13201 aggcttcaat tcatttggct tcactttttc tgtttctctt atgatataaa caggacgctg
    13261 tttcgtttct aagaagattt tcccaatata tttcccgatg attccaagac ataacaattg
    13321 gattccacca atgaacagga agatcgagac catggaaggc catcctgatg taggatcacc
    13381 aaacaacaat gcccgcaaaa taatgaacaa aattgcaata ccagaaccga cacaagacaa
    13441 agcgccgata aatgaagcaa tcgttaacgg tgcatccgag aagttcacga taccatcaat
    13501 cgagtagttg aataatttcc agaaggacca agatgtttcg ccagccacac gttcgcggtt
    13561 ttcataagaa atatattctg ttttaaatcc gacccagcta aataatcctt ttgaaaatcg
    13621 gttgtattct gttaattcta ggacggcatc caccatttga cgagtcatca agcggaaatc
    13681 acgagcgcca tcgaccattt ctgtatcgct gattttattg atcaactggt agaatttttt
    13741 cgcaaagaaa ctgcgtatcg caggctcgcc ttcacgagtc gaacgccggg tgccgacaca
    13801 atcgatatca gaagtagtga tccggttgat catctcagga agcagttcgg gcggatcttg
    13861 cagatcaaca tccatcacgg tcactaaatc tcctgtagaa gcttgcaatc cagcgtacag
    13921 agccgcttct ttcccaaaat ttctggaaaa tgagacaaag cggacataag gataagctga
    13981 ggctagcttc ttgattgctg ctaacgtacc gtcttttgat ccgtcgtcaa taaacaaata
    14041 ttcgaactca tgggcacctt tgaatttttc aacctcatca aaaaaaagag gaacagtttt
    14101 ttcttcatta aaacatggga caacaattga tactttcatc gtttctatcc tttcaatcgt
    14161 atgtttatat atggtttaca ttcaaaattt aataaacctt aaataacacc tttaaaattt
    14221 gattttacgt aaaagaacag gtattctttt tgtaaactaa cgtatttagt ttaccatgtt
    14281 tcctcggttt atcaaacttt taagaacaat ttttattagt tggcaagtag ttttggatag
    14341 agaaaaagga ggaagttcca gtctattgac taggagcaaa caaaatgaaa atacacacac
    14401 ctatcggctt tttatggtta gatgcagatg aatccggatt gactgctgta tcttttcagc
    14461 caatttcaga aagcgaatca gcgaatcagc gaattttaac gcgcacacaa gaacagtttg
    14521 aagaatattt tgcgggaaaa agaaaagaat ttgatgttcc tttatctata aagagaggta
    14581 cgccttttca gcaaaatgtc tggaaagctt tgtcgaccat tccttatgga gaaatccgaa
    14641 cgtataaaga agtagccgtt gctgttgata gtccgaaagc tgtgcgagcg attgggcagg
    14701 caaatcgaac caatccattg ccaatcgtta ttccttgtca tcgagtgatc gggcaaaatg
    14761 gaaaactgac aggatatatg ggaaacgcaa tagatggggt tgaaatcaaa cgccaattgt
    14821 tgttgttaga aggatatctg caaaattaaa aacagttgtg attcggacat tgttccatgc
    14881 gagaatcaca actgtttttt catgttcatt ctaaactttg atcagccaaa taaatagtaa
    14941 agccatcact gtttggagaa gcccgacagc taatccataa gataagaagc gtgtaccttc
    15001 tttcatgaat tttgcaaagt ctaaacgcag accaattgcc gctaaagcag tgatctcaaa
    15061 ccagctgctg ataaaatgtg ccgattggtc aataactaca ggtaaagaaa acaagctgtt
    15121 gaccaaacaa aagatcacaa accctaatac ataccaagga agcggtaatt ttcgtttttt
    15181 ctgcgtatca gttggcgttt caaacagagc tggttgtttc ttgtgcatga atttttcaaa
    15241 cagatagaca acaacaacga gcatcataat acgtagaatc ttaaatagca tggcgaattc
    15301 gacaacagaa ttgtcaagta agcttgcccc agcgactact tgaccaacag attggagtgt
    15361 accacccaaa agtgcacttt tttcaatgag atttccacca aacaactgta atccaagaaa
    15421 agggagagtc aacatcatca cagtacccag tagattgact agtgtgatga tctgtccttt
    15481 ttcttcctct ttcgcatgga tggaaggggc gattgaagca atagcagaag aaccacaaac
    15541 agcgtttcct ccagccatca tcaaagaaga agtatcgctg aattgcagtt ttttaccaat
    15601 caagtaagca ccgatgatag tgactgacat ttgcagtaac acaaaaacaa ttccttttac
    15661 accaatttga gcaatcgttt gagctgtgac agttgcacct agtaaaaaaa cagagaattc
    15721 taatagtttg ctttcagcaa attttgtgcc gattgctaga acaggctgtt taaaaaaagt
    15781 atttcctaat aaaataccca ataaaatagc aatagtcgct ccacctaact gtggcagata
    15841 aatagcaaga agcctgctga aggcagcgat ggcaaaagaa agcagtaaac cgggtaagat
    15901 ttcgcggacc gctgaatcct ttacagattt tattggatgt gacaatgatt tcatttgatc
    15961 ggttcctttc gtcaataaat actaaaagca tactcgaaca tagtagcact aaaccagtat
    16021 tttgacaaaa gaacaagagg tcgtgacaaa agtcttgtac gacctcttgt ttcgaataaa
    16081 cggtgttcca gaagtagctt ctacggaaat aagccgaaat ttcacaaaaa tttgagaagc
    16141 aattttcgta aattccttct tatttcttga agctgaccac ttcttttacg acctcttggt
    16201 aaacggtgtt caaaagcttg catctgcggt aataagccca accagtacaa aaacatgaac
    16261 agctgttttt gtttggccgt tcttattact tgatgcagaa cagctttttc acaacctatt
    16321 gaatcgatta ttaagcgatt tttttagaaa caaattttcc atgtttgcta tgttctttaa
    16381 ttaagaaacg tacgtaatga gcaagaacgt agaagacaac tacacttgca aacagacatt
    16441 ccgcaacttt taagaaatcc aatacgctac tatagatacc taaactgttg aagtaatgaa
    16501 cagtagtaaa tatagctgtt gcagagataa caagcgggaa tgtaaaggct gcatagcttg
    16561 gataaaaacg aagcttgaac aaacgtggaa gcatagacag cacaacgaaa tacaatactt
    16621 gagataaagc gaacaatgct acgacaagat aaaaattagg ttcagcaaag tttttaagat
    16681 aacctgttag gcaaagagaa ccaggtgctg caacgatcgt aatcagcgga cgtgtcggat
    16741 gagccatatt tcttacgaaa aagacacgtt tgatgatgat cggcaataag aacgcatagc
    16801 agatcaatga aatccaaaag aaaatttttc caataagtgg gaagaagttc ccggcagtta
    16861 cagtgatgac cccaaatcca acgtaaatga taaaccagct tggataaatt gcttcaattg
    16921 aaagatcagc tttgataaca tggtgataat tgaaataaaa gacaaggatc acttggaaga
    16981 taacagcgca cagccaaatg aatttgacaa ttggtgcaat actttcatat gaaacaaaat
    17041 aagtacaaat aaccatgagt gacatcgtaa aagttggtga aacggaggcg atgattggat
    17101 catgcaacgt ttgtttcgtg tgttcgaata agataaacaa tttaacaaaa atgaatatca
    17161 taagaatcat agagataccg ccagttagat tgcctaaagc aacatggtga tagtctttaa
    17221 acagatttcc aagggaagct aacccaagga tcaacccgca gatcgggatc ggaataattt
    17281 tcaaaaagtt cttcatatat aatattctcc tttttattta atagatttta gtaccaagat
    17341 gaacgaatac attgtaaaat gaataggaat gtatgattac gagcaagcag acagctgatt
    17401 gtcttcatct aagttactag ttggatcagc aactgttttg ttgtacattt ctattataga
    17461 tggttttttg tatatttaaa tcaaatagtt tttatagtaa ttatcataaa aagttatgga
    17521 agtggtgcca tgtttaagtt attaacgact tttcgagcag tatatgaaac aagaaatttt
    17581 tccagagcag cagaagtact gtttttatct caaccagcag tctcgaatca aatcaaacag
    17641 ttggagcggg aattgaatat cgatcttttt caacgtaacg gaagaaaaga gatgcttcca
    17701 actaagcaag ccgacttatt atatgaacgg acactggttt tgttagaaga atgggaagaa
    17761 actcagcaaa aattgctcaa tgaacaaaat gaagaagaag tatgtcggat cgttgcttcc
    17821 cacacctttg ctgtctatct tttgcctcag ttgatgaaac atctgatcaa aaggtttcct
    17881 aaagtgcatt ttgagatcga aatcacgaat tctcatgaat cattagaaca agtagcgaaa
    17941 catgaatccg attttggttt tatcgaaaag ccattagaga cttccggcgt acaaagatac
    18001 tctttgatgg aagaccagct agtcatcgct ggggacccaa aaagcaaatt gtggcttgta
    18061 agagaagcaa actctggtgt ttttcattac acgcagcgtt attttgaaga gatgaatatc
    18121 caagataaga agatgatcgt gaaaagtaac gatgtaattg ttgcgttgct gaaggaagga
    18181 atcggtcgct cgattttgtc taagcgctct gttccagaaa atgtgccaat gactccgttg
    18241 aatttccatc gatattttta tttcatccaa cgaaccaatc tggtttctga tcagctgcta
    18301 gagattgccg aagagatcct tcgatacaat gaaagcacag aaacttctca cagcgaggag
    18361 aatctcagct ggtagataat tgcatgtatc aaaaaaagtt ctatgataca ctaaagataa
    18421 gcagtaggct tttgtactgc atttgctcaa gcaactgcac aaacggaaag ttaatttttc
    18481 ccaaatgtct atggaaagac tttccattat ctaactggac cgctataata atcagcagta
    18541 tggtttttaa gaaaagggat gaaacatgga aaaaaaatta aaagcttcga acgataatcg
    18601 tattgattat ggcgtgattt taccagtctt tctgttatgt ttgattggtc tgctctcatt
    18661 atatgtagca cttagccatg atccgaacaa tccagcagtc ttgaaaggcg tagggatgca
    18721 agttgtctgg tatttagttg gagcggcagc aatcgttgtc atcatgcatt tgaattccaa
    18781 atggatctgg aaactgactc cttaccttta tggtttgggg ttagtggtaa tgggactctt
    18841 gctcaaattc tatgatcaga atttagctgc ttcaacaggg tctaaaaact ggtttcgatt
    18901 cggtgcgttt actttccagc cagcagagtt gatgaagatt gcgtacatct tgatgatggc
    18961 actgatcgta actaaacata atacgcaagt aaaagaacgg acgatgaaat cggacttttg
    19021 gctgattggg aagctcttga tcgtgacaat accggtttta gcattgatca tggcccaaga
    19081 tgactttgga acgatgcttg tctttcttgc gatctttggc gggattttcc tgatgtctgg
    19141 aatctcttgg cgcatcatcg cacctgtagt aatcttggca gtagtcgttg gagcaggaac
    19201 gatcttcttg gttacgactg aaggcggaag agacttgctt tataaagttg gattcaaatc
    19261 ttatcagttt gcacgtattg attcatggct ggaccctttc catgatacgt caggaatgag
    19321 ttatcagccg gcccaaggac ttttggcaat tggtaccggt ggcttgtttg gtaaaggatt
    19381 caacgtaagc aatatctatg tgcctgttcg tgagtccgat atgattttta ccgttatcgg
    19441 tgaaaacttc ggctttatcg gtggtgcatt cgtcattttc ttgtatttta ttttaatcta
    19501 tcgtatgatt cgggtgtgtt tcgatacgaa taatgaattt tacgcctata tcgcaagcgg
    19561 tttgatcatg atgctgctgt tccatgtctt tgagaatatt ggagcaaata tcggattact
    19621 tcctttaaca gggatcccat tgcctttcat tagtcaggga ggatcctcga ttttagggaa
    19681 catgatcggt atcgggttga tattatcgat gagataccaa aatgaagcac ctgcaagatc
    19741 ttcaaggagg taagaaaatt gtacaccttt tactggtacc cgaaatgttc aacatgcaaa
    19801 aaagccaaag cgtggttaga ccagcatggc gttagttatc aaaccgttga tatgatcaaa
    19861 gaagtaccga aggcctcaac gattgagact tggctagaaa cgagtcaagt accaatccgt
    19921 cgcctgttca acacaagcgg gatgaaatat cgggaacttg gactgaaaga tcaagtaggc
    19981 gagtttacgg cttcaaaagc gagccaagtc ttatcgacag atggtatgct gatcaagcga
    20041 ccactgatct tacgagagga ccagcttgtt gcaattggat tcaatgaaaa aatttatgaa
    20101 ggagaactga tataaaatgg caggcaagca tttgaagaaa aaggacaacc tttggatctt
    20161 atttaatgga aaagaatact gtgttggttt gacaaatgaa gcgcaagaag aacttggaga
    20221 catcacgttt gccaatctgc caaaagcagg acaatcgcta aaaaaagatg aacctctgat
    20281 cgaagttgaa gcggaaaaag cggtcaatga atttgccagc ccgctaacgg gtacagtttc
    20341 ttctgttaat gataaaatcg gtgaagatat caatatcttg aatgattcag atgaaatgaa
    20401 tgcgtggatc ttaagtttca aagatgttga tccaaaagaa tttgacgaat tataaaatca
    20461 gaaaatcact tgaaaaaagt tgacactgat tcttccagtt gctataatca taagcaatcc
    20521 tatatgaaac gagaaagctt tgaaaagaag agtacatgtc acggacgttt gaagagagcc
    20581 ctgtttgctg aaaatgggta acgaaaatga gatggaagat ggtcttagag cagagtaagc
    20641 gagcgtaagc aaacttacta cgggagtgcc cgttacagcg cgacagtata cggaaagaag
    20701 ctaagtccaa gtactggaag aggctgttat tgcgaagtaa cggtaaatca aggtggtaac
    20761 acggaagttc aagctttcgt ccttttgctt aaggcaagag ggcgaaggct tttttgtttg
    20821 aaaaatcata agagaaagat gtgaatggca tgtcattaat ccaactaacg aatgtcaaaa
    20881 agacattcaa tgggaaaaac ggaaacatcc aagccgtcaa tgacgtttca ctaaacgttg
    20941 aaaaagggga tatttatgga atcgtcggct attctggcgc aggaaaaagt acattagtcc
    21001 gtctcctgaa tggacttgag cttcccacga gcggcgaagt gatcgtaaac gatcaagata
    21061 ttacaaaatt aaaaaacaaa gaattacgta cattccgaaa gaaaatcggt atgatcttcc
    21121 agcatttcaa cctgttatgg tcaagaactg tacttgaaaa tatccagctg ccgctggaat
    21181 tagctggcgt accaaagagc aaacgtaaag aacgggcaga agaactgttg cgtttagtcg
    21241 ggttagaagg acgcggacaa gcatatcctt cacaactttc cggcggacag aaacaacgcg
    21301 tcggtatcgc acgagcattg gcaaatgatc ctgagatcct gctttgtgat gaggctacta
    21361 gcgcattgga cccgcaaaca acagaagaag tattagactt attgttagcg atcaataaga
    21421 aattgaattt gaccatcgtc ttgatcacac atgaaatgaa tgtgatccgc aaaatctgca
    21481 acaaagtcgc tgtgatggag ttggggaaag tcgtagaaga aggagacgta ttgactgtct
    21541 tcagacaacc gaaaaaagaa gtaaccaaac gctttgtaca acaagacatc gaaccagaag
    21601 ctgattcgac agaactatta gctgaactca tcaaagaaaa tccaagcggc cgtttggcaa
    21661 ctttgacctt tagcgaaaga aatgccaacg agccagtcat ttcccaagcg attcgacgct
    21721 ataacatcga tgtcaacgtt gtgtatggaa agatcaaaca agtgaaagaa ggttcctttg
    21781 gttcattgac tgtcttgatg actggtgaaa ccaaagaatt agatcaagca gaagtgttca
    21841 tcaaagaaca aggagtagga attgaggtga tccatcgtgg ataaaagctt ttcagaaaca
    21901 tatctagatt ttaaacaaat caacccggaa acgatgaatc aggctatcct tgatacacta
    21961 tatatgacat taatctcaat ggtcttagtg acgatcatcg gattagtttt gggattgatc
    22021 ctttactcta ttggacgcaa aaacaaaccg tatgctcgaa tcatttatgg aatcgtatcg
    22081 atcatcagta atattttccg gtcaacgcca tttatgatcc tgatggtttt gatcattcca
    22141 tttactaaag caatcgtagg cactatgcta ggtgcgcaag cagccattcc agctcttgtt
    22201 ttatccgcag caccatttta tgcccgtcta gtagagattg cttttcgtga agtcagccct
    22261 ggtgtactgg aagcagcaga tgcaatggga gcaagttact gggaaatcat ctggaaggtc
    22321 ttgatacctg aaagtattcc cgcattgatt tctggattaa cagttacaac gatctcgatg
    22381 atcggattta ctgcgatggc cggcgcgatc ggcgcaggtg gacttggagg tcttgcttgg
    22441 caggaaggct accagcgtgg taatctaaca gtgacattcg ttgcgacttt aattatttta
    22501 ctaatcgtat ttatcgttca aggaatcggt gatttcttaa ctaagaaaac agacaaaaga
    22561 taataggata tagggggatg taggatatga aaaagaaaat ttttggattt gcagcagcgc
    22621 ttttgctgac tgtaggatta gcagcatgcg gtaacaacag cgacagcaaa gattcagcaa
    22681 ataaagcaga cgacacgaca ttgaaagtcg gcgcttcacc gacaccgcac gcagagattt
    22741 tggaacatgt gaaaccatta ttgaaagatg aaggaatcga tcttgaaatc gtcaaattcg
    22801 atgactatgt attaccgaac caatctttgg aagaaggcga cattgatgcc aattacttcc
    22861 agcatattcc ttatttgaac aaagaaatca aagaaaaagg atatgacttt gtcaatgccg
    22921 gtgctgtcca catcgaacca atgggcttgt actctaaaaa agtcaaagat gtttccgaat
    22981 taaaagatgg tgcaacaatc attacttcaa attctgaatc agactgggga cgcatcatca
    23041 caattctaca agatgctggc ttagtcaaag tcaaagatgg agtagatctg gaaacagcaa
    23101 cattcgatga tattgaagaa aaccctaaga acttgaagtt caaccatacg atcgacccat
    23161 cacttttagc ttctacgtac caaaatgatg aaggtgacct agttgcaatc aacgcaaact
    23221 tcgcttacgg cgcagggttg aatccattag aagatgccgt attgcttgaa aaggacaact
    23281 ctccttacgt gaatattatt gcgactcgta aaggtgatga agacagtgac aaaatcaaaa
    23341 aactgattga agtgcttcac cgcaaagaag tccaagaatg gatcacagac aaatggggcg
    23401 gctctgttaa accagtaaag gctgatgcaa aataaggtat ggaacaaaaa agatgagaaa
    23461 taagtctgta atggcttatt tctcatcttt tttataccta ttctaattta gaaatcaaaa
    23521 ttgtttaata ataaataaaa gatatttgat tttagtaagg aaggtcattg cgcttcattc
    23581 tcaattagtc taaaatgagt gagaacgaaa gagaatttgg gggtataatg catgtctgtc
    23641 ttagaaataa aaaatctaca tgtgtcgatc gaggaaaaag aaatccttaa aggcgtaaac
    23701 ctaacaatga aaaccggaga aatccatgcc atcatgggac ctaacggcac aggaaaatct
    23761 accttatctg ccgctatcat gggcaatcca aactatgaag taacagaagg cgaaattttg
    23821 tttgacggga aaaatgtttt agacttggaa gtagatgaac gtgcgcgact tggcttattt
    23881 ttagctatgc aatatccaag tgagatacca ggtatcacga atgcggaatt catgcgtgca
    23941 gcgatcaatg cgaaacgtga tgaaaacgac aaaatttctg ttatggcatt tttgaaaaag
    24001 ttagatgaaa aaatggcttt actaaatatg ccagaagaaa tggctgaacg ttatctgaac
    24061 gaaggttttt ctggcggaga aaagaaacgg aatgagatcc tgcaattgtt gatgttagaa
    24121 cctacatttg caattttaga cgaaatcgat tcaggtctgg atatcgatgc tttgaaagtc
    24181 gttgctaaag gagtaaatga aatgcgcgga gacaatttcg gtgcattgat catcacccac
    24241 tatcaacgat tattgaacta tatcacacct gatgtcgttc acatcatgat ggaaggccga
    24301 gtagtcatga cagggaatgc tgacctagct aaacgtctgg aagcagaagg ctacgctggt
    24361 atcagtaaag aattaggaat cgactataaa gaagaagaag cgtaaggggg agcaagaatg
    24421 aaagaaaaaa actggctcga ttatcttgac gcggtaaatg atttttcttt aagtaaaggc
    24481 gaacctgatt ggatgagaac cttccgtcaa gacgcactag cgaaagcaga tgaactgcca
    24541 ttgccgcata tcgatcgggt gaaattccat cgctggtcgt tatttgatgt gaaagaaaca
    24601 caaaccatca gtgaaacagg cacgattccg gcatttgatg caatgaaaga caatcctgtg
    24661 cttgtccaac aaggttcatg gacgattttt gaacaactgc ctgtggaatt agcagaaaaa
    24721 ggagtcattt ttaccgactt gttcactgca atgatcgaat atccagaact agtccaagaa
    24781 tattatatga aaaaagcagt aaacatgaac gaagaccaat tgactgcact ccatgtagct
    24841 tttatgaaca gcggtatttt cctgtatgtg cctaaaaatg tcgtgatcga tgaaccactc
    24901 gagtccttat tcattcaaga tggcgcatcc gatgagcact tcttcaagca tgtgttgatc
    24961 gtggcagatg aacatagtga attttcttat ctggaacgtt tccagacaac caaagaacaa
    25021 gtagcaaaat catcaggtaa tatcatcgtg gaagtcatcg ctaaagctgg ttcaaaaatc
    25081 aaatattcag ccgtagatca attaggagaa aatattactt cttatatgaa tcgccgtggg
    25141 cacattttac gagatgcttc tgtcgactgg gcaattggtg tcatgaatga cggtcatgtg
    25201 atcgctgact ttgactcaga tttagcagga gaaggtgcac acgcagaagt caaaatcgtg
    25261 gcaatcagct cgggcagaca aatccaagga atcgatacac gagtaaccaa taaagcccct
    25321 catacgatcg ggcatatttt gcaacacgga gtgatccgag aaaaaggaac attgaccttt
    25381 aatggtatcg gccacatctt gaaaggggca aaaggtgcag atgcccaaca agaaagtcgt
    25441 gtcttgatgc tttctgataa agcacgtggt gatgcgaatc ctattctttt gatcgatgaa
    25501 aacgaagtaa ctgctggaca tgctgccagt gtaggacgag ttgatccaga agaaatgtac
    25561 tatctgatga gtagaggatt gcataaagaa gaagcagagc gcttagtgat tcgaggattc
    25621 ctcggttctg tcttaacagc aatccctgta gaacaagttc ggaaagaatt agtcgaagta
    25681 atcgaaggga agttgaatgg atgatcgatg ctaaaaagct acgcaatgat tttcctatct
    25741 tatttcaaga cgtcaatgat gaacctttag tttatctgga taatgcagcg acgacccaaa
    25801 agccaaaaca agtactccag gcattagcgt actattacga acacgataac gccaatgttc
    25861 atcgcggtgt ccatacgtta gcagaacgcg cgacccatga ttatgaacaa gcaagagaaa
    25921 aagtacgggc gttcatccat gcaaaagaaa cagcagaagt gctgtttact cgtggtacga
    25981 cgacaagctt gaattgggta gccagaacct tcggcgaccg ctatatcaaa gcaggagacg
    26041 agatagtgct ctcttacatg gaacatcatt ctaatgttat cccgtggcag cagttggcaa
    26101 aacgaacagg tgctgtcttg aaatatatcg aactaacaga agaaggcttc ctggatatgg
    26161 aggatgcagc gaaaaagatt acggacaaaa ccaaaatcgt ctccattgct catgtatcca
    26221 atgtcttagg tgtcttcaat cctgttcaag aattagctga acttgtccat gaaaacggcg
    26281 gggtcatcgt agtagatggt gctcaatctg ccccgcacat ggccattgat gtccaagcac
    26341 tagactgtga tttctttgct ttcagcggac acaaaatgtg cggaccaaca ggtattggtg
    26401 ttttatatgg taaacgaaaa tggttagaag aaatggaacc tgttgaattt ggtggcgaaa
    26461 tgatcgattt tgtcgaatta tacgacagta catggaaaga actaccttgg aaattcgaag
    26521 cagggacacc aaatatcgcc ggcgctatcg cattaggcca tgcaatcgat tatttgcaaa
    26581 aactcggtat ggacaatatc catcgatatg aagaagaact agccgcttat gtgttgccaa
    26641 aattacaagc aattgatgga ttgactgttt atggtccaca agacccgaat tttcggacag
    26701 gagtcgttgc attcaatttg gatgggttac atccccatga tgtcgcgaca gctttagaca
    26761 tggaaggggt agccgtcaga gcaggtcatc attgtgcgca accgctattg aagtaccttg
    26821 aagtatcagc gactgctcgc gcgagctttt atttctacaa cacaacgcaa gacgccgacc
    26881 gtttagttga agcaatcatg gcaacaaagg agtttttcca acatgggact atctaaatta
    26941 gacaatttat accgtcaagt gatcttggat cattcttccc atccgcatca tcgtggaagc
    27001 ttgactgact cgacaagcaa gatcgaattg aacaacccca catgtggaga tgtgatcgaa
    27061 ttgcaagtcg atgtaaaaga cggaatcatc aaaaatatcg cctttgacgg cagtggctgc
    27121 tccatcagta cggcaagtgc ctcgatgatg acagacgccg tcatcggaaa atcaatagaa
    27181 gaagcagaac atttaactgt agactttcta cagcttgtcc aaggaaaaga agtcaaagat
    27241 cccgaccaat taggcgatgc tgctatgctt ggtggtgtag ctaaatttcc cgctcggatc
    27301 aaatgtgcga cacttgcctg gaaagcacta ggaaaagcaa tggaaaacga tggtaccgca
    27361 gctttccatc attaccacaa ggaagaggag tgagaacatg ggcgtaccag aattagaaga
    27421 atataaattc gggtttcacg atgatgtcga accggttttc agtacaggag aaggcttgac
    27481 agaagaagtg atccgtgaga tgtcaagaat caaaggcgaa ccagaatgga tgcttgaatt
    27541 ccgtctgaaa tctctagaaa catttaacaa aatgccaatg caaacatggg gccccgacct
    27601 ttcagacatc gatttcgatg ccatcaaata ttaccaaaaa ccaagtgaca aacccgctcg
    27661 tgactgggaa gacgtaccag aaaaaatcaa agatacattt gaaaagattg gtataccaga
    27721 agctgaacga gcttatctag ccggtgcttc cgcacaatat gaatcagaag tcgtgtacca
    27781 taatatgaaa gatgaattcg aaaagttagg aatcgtcttt actgacactg actctgcttt
    27841 gaaagaatac cctgaattat tcaaagagta cttttcaaaa cttgtaccgc caaccgacaa
    27901 caaattagca gcgctgaatt cagccgtatg gtcaggtggg acctttattt acgtgccaaa
    27961 aggcgtcaaa gtcgatgttc cattacaaac gtacttccgg atcaatgcgg aaaacacggg
    28021 gcaattcgaa cgtacgctga tcattgttga cgaaggagca agcatccact atgtcgaagg
    28081 ttgtacggca cctacttatt caagtaacag cctgcatgcc gccatcgtag aaatctttac
    28141 aagaaaagat gcgtattgcc gttacacaac gatccaaaac tggtcagaca atgtgtacaa
    28201 cttagtaacc aaacgagcaa aagcatacga aggcgcaacc gttgaatgga tcgacggaaa
    28261 cctaggtgca aaaacaacga tgaaataccc aagtgtttac ttagatggaa aaggtgcacg
    28321 aggcaccatg ctctccatcg cctttgcagg agcaaaccaa atccaagata cgggtgcaaa
    28381 aatgatccac aatgcaccaa atacatctag ctctatcgtc tctaaatcaa tttcaaaaga
    28441 cggcggagaa gtaaactatc gaggacaagt aacctttgcc aaaaacagtg cgggttcgat
    28501 ctctcatatc gaatgtgaca cgatcatcat ggacgaatgg tcgaaatccg atacgatccc
    28561 attcaatgag atccacaaca gccaagtctc tttagaacac gaagccaaag tctcaaaaat
    28621 ctcagaagaa caactctact atctgatgag ccgaggcctg accgaatctg aagcaactga
    28681 aatgatcgtc atgggctttg ttgaaccatt caccaaagaa cttccaatgg aatatgcagt
    28741 cgaactcaat cgattgatca gttatgagat ggaagggtct gtggggtaat acttaaataa
    28801 aggctaggaa cctgataaca tcaaggttcc tagccttttt ataataaaat gaagcgaaaa
    28861 taatttcttt taaagagccg agattatcag ctatataaga gtgaatttga tgcaaaaaac
    28921 agagccgaaa cagtcttggt gttcgtagct ctgcttatat gtttcgaatt taagacaaag
    28981 agttggcaaa agatgttgat aaggaagata agataactgt gttatataaa ctaggtaact
    29041 aactgtaaca agctaatttt aagagattct tattagaaga cgtttaggaa tataactaag
    29101 aaaatgatta tacaggtaat tgtcatttca ataatgtttt ctaattttcg cgtctttgtt
    29161 ttaagaaaaa ggccagaatc agttggaaaa aagttcgtac gatagtgaag aggggcaaaa
    29221 tttcctacta atattcccac taacaagaga taaaacggcc aggttggtgt gattcctcta
    29281 taaaaaaatg cccatgctac cgaaatccca tagattaaca actgaacaat ttttacaatg
    29341 aaaaaattgt tctgccatta ctcaaagtct cttcctcctt gtatcgttta tttgtttcat
    29401 tttatcatta tgataggcgc ttgaacaatc cattttgtat tttattgagt actcttggat
    29461 aaactaccag cgattatcat atttatttat gttactgtaa gccatcatat aaaagtaaat
    29521 gagcagatca tagaaatata aaaaagaact aaaattgatc taaattatgt gcagcttgac
    29581 tacgtaccaa tctatattac ttactagatt ggtcgttaat ctattcggat cgaatgagca
    29641 aaatattttt gtgaatgtcc atccttgatt atgattccaa aaagaatcat tgggaggctg
    29701 tggcgtaaat attatactat aagccagaaa tacctatcat tctgaacttt tttatttagg
    29761 aactttcatc tcaaggcttt ttcaattaat ttgtacccct gttttttgga taagatcatg
    29821 tgcattgatt ttttctatct ctacgttcat ctcctactta atgcctatct ggctcctgag
    29881 ggcttctttt taaggcgtcg tcatagtctt ggctgaggat ttcttggtaa tctgagggaa
    29941 tggcttccca agtgagcagg cgaacgttca tgacgtgttt tcctttgtgt ttgattacag
    30001 catggttttt ctctttttct acctctccag cgtgaaaaga cagccatgta ccatggccaa
    30061 agatatcatt acatacccaa cgttcgatgg aattgtccac gtatcctaca gggagtgtgg
    30121 tatagccgat ttgtggtttc aaaaaaggat tgaatcgatc gatcgtttca tttttgtatt
    30181 gataattgat aagaaaaaga tagaccaaac aaaagacgag cagaaagaaa gatagtgtct
    30241 ttttgagtga gaagggttgt tttgatgaat aagatttctt gttaacaaga ggttcatctg
    30301 gcaatgttgg ttctattgat tcggtagctg attcaataga aggaaaatca atcggcagac
    30361 ctaaagtatg atgtaaaagt gacagcattt caaggtctgg cattgtacga gaattttccc
    30421 aactagaaat cgttttatcg gaaacaccaa ttttttcgcc taattctttt tgcgtaagct
    30481 tacaatttct gcggtaagtt cgtatttttt ctccggtgtt catcttcttc tcctttcgat
    30541 tctacagtat atagatttat tctacatgac ctatacactt gatagatacg tttttttgat
    30601 gaaaaacggt atgattttat caaagaatca tttaagtaag ggagagtggt gataatcaaa
    30661 aaaaagttca cagttttact cacaatcata gtgaccggta tcatgagtgg ttttgccttg
    30721 gttagtataa ataaacaggt actctatcgg acaaatgaat ttttccatca aacagatact
    30781 tatactccga ttcgattgcc acaacatttt attgggcaag aagaatatga gcagctaatc
    30841 atggtatttg aaaatgtctc atcagaaact gagctttctt atatgaaaaa aacagtaaat
    30901 gaatccaatg aagtagatac atcttggaac ttcaagatac agccaaagct tgaaatgaca
    30961 ttgtattatc aaggggatgt caaatcttct cacgagaagg taccctattc taatacctcc
    31021 tttcgcgtaa cgtccattga agaatcgatc aaaataaaag attttgaagg tgaatttttc
    31081 ttgatgacga gagaaaaaga agcctatgaa cggttcattt cactattcac tgatcgattc
    31141 aatcaagcat ttcacactga ttatgccact aatatttttg aagactttga aaatagctat
    31201 tcgtattcgg ttatttcaaa tacagacgta tataattatc gagtgtattt aactattgga
    31261 ttgattcttt tattcctttt gttatcatcc tttttcttat tgatgaataa agaaatcagt
    31321 ttattgttga ataatgactt ttcattacat caagtattgt ggtgtttatt ggggaaaaag
    31381 aaaatcatta ttacattcat aattgcagga atcattggtg gttttatttt tatgtattat
    31441 aaggagcaat ttctttattt gttccagatg tacgttttct tgttcagcgg aatatatggt
    31501 atctctttga tttctctttt attagttgaa aaaatcgctt cgttaagaga agcgttcaac
    31561 tatatccaat acattctttt tacatttgga ttgttgtttt ctcttctttt gaccgttgcc
    31621 aatgtcgaat tagcaactat cgttttttct tcttcacagt tagctgtttc ccatgaacca
    31681 ccaaaagaaa tcgctggtga ggactatcat gtattttatc cagtaaccat cgggaaaaac
    31741 cacgtggatt ttatttattc caatcgtttt gcatcagcag cagatcagga attatatgaa
    31801 actttgaata aaaacggaag tatattagtc aatgtatcag attacttgaa tgaagaaaat
    31861 gaacagtttg gcagagggat aaaaataaat ctgaattatc ttaagaaatt tcctttgatt
    31921 gatgtctctg gaaggttgat ccaaataacc gaaaaagaaa cgcaccctgt tatattgatc
    31981 cctgaacgat atagacatac agatttaaaa aatgacctgg cgcaaataac agaatattat
    32041 caagaaatca gtgaaaaaga accgaaattt ctatttataa aaaacaatca acccatttat
    32101 acatttattc cttctatccc ctggatcgaa cattatccgg ttgttgaaat actgacattg
    32161 aaaaacagta tgtatttgga aagaaatatt ctcagcggag aaatctatcc accgttaaag
    32221 atcaagatag gctctttgtc gaaagaaagg ttatttgagc tgattgaaga aagtcagtta
    32281 cgtgataact tgcagttatc atttccgtat actcagactg aagagatagc tgtcaaagtg
    32341 ttaagcagat catttcatta cttgatacag atatttttac tcactttctt ttctttcttc
    32401 ttgttgagct atgtcatgtt atgcatatat tttgtctaca attgtcggaa aatcgctatc
    32461 tttcgttcaa gtggttattc gctctttgaa acgtataaag atttcttcat gatgaacctc
    32521 atcaaatggg gaacgacaag tgtaatcttc ctttttctta tagaaagaga gcctaaatat
    32581 ctttttaata tttttttctt tagcttcatt gattttattc tttcagttgt ttttattttg
    32641 tctacagaaa agaaaagtca gttattgctg atgaatggag gttaacaatt ggagccgttg
    32701 atagtgataa aaggtgcgaa aaaaatcatt cgaaacaaaa cgattcttca tttggatcgt
    32761 ttcactgcgg atgctgggga tcttgtgact gttgttggag aaagtggagc aggtaaaagt
    32821 acgttattga atatattagg attgaatgat cagttcagtt caggacaatt ctatttgttc
    32881 gatcaagaga cgaaacaatt aactgggaga gagaagcgct tgataaaaag aaataccata
    32941 tcttttcttt ttcaagattt tgggttgatt gaatatgaaa caatcgattt taatttagat
    33001 attggattga agttttcgaa tttaaatgtt tcagataagc gaacagcaaa gtatgaggca
    33061 ttgaaaaaag taaatataaa caagaagcta agtacgccta tctacacatt atctggtggt
    33121 gagaagcaaa gaatcgcctg tgcgagagtc ttattgaaga atagcaaaat cattttagcc
    33181 gatgaaccga ctgggtcatt ggataaaaga aataaggata aagtagttga aatcttatcg
    33241 caacaagctt cccaaggtac gttagttatc gtagtcacgc atgatccata tctgaccaaa
    33301 ataggaaaca agaagatcat gctttaaaaa tcaaaaagga aaggatgtcg ttttatgaaa
    33361 aaagcagtta ttatttgtgc actagggata ggttttgttg gaggaaacgc tatgtcatct
    33421 gaagtggaag caaattcagt tcacggtgaa atctattaca aatctttaaa gccaggagag
    33481 attcattttg atgctaaagg taatattatt aagtcaaatt taccagtaga ccgggaaatt
    33541 tctagaacag caattaatca tagctctgga agatgggttt attatagtga tacaacttgt
    33601 acgagaaaaa caggtcattc taaccactat agtcgtgtct ataatcgtca cggtgcaaaa
    33661 gcgaaagttg gaaactctat tcgatcagca aatgcaacaa aaggagtatg ggcctatgca
    33721 agtgcgacag gaaatagaac tgacacattc tcatgttggt acaatccaac cggttggtat
    33781 taagtatcca aaagtttata taaaatagaa aaaacatata atgaaacagc gttaaaagtt
    33841 atttttggta gttttaatat attcattttt agttgtataa aaatatatca taataaaaac
    33901 aacaaaaaaa tgtctggaaa atcgaacata aaagtgtctg atttgaatat cccagcagcg
    33961 gaagaagaaa aacaaaatcg ataacatttg ttctaagaat tagttacgtt aaatacggaa
    34021 cgcaagatag acttgaaaaa cggtaacaaa agaagtagta tattaaggtg tgatgtgcta
    34081 cttgacattt attctgctga gcgaactttc tggattgtgt agccttatat ctattcagga
    34141 cgtatcgagc agattagtaa aggtgttctt gatgattttc atcttgaaca cctttgtttt
    34201 tagcaattcg caaaaaacga aaagtaggag aattgataaa tgaaaaaaag atttttagca
    34261 cttgccatcg tactaggcac tggcttattg tcaggctgta cgaatgccgg tgaaaaaaca
    34321 gccgttagtt ataaaggcgg tacaatcagc gaacaagaag taatggatag cttgaaaaaa
    34381 atgcaaggag cagattccgc tgtgcaacag ttgatcgttt atcaagtatt tgaagataaa
    34441 tatggagatg acgtatcaac caaagaaatc gattctcaat atgatcaaac aaagaaacaa
    34501 ttgggtgatt catttgattc acaattgaaa tctgcaggtt acacagaaca aacattcaaa
    34561 gacagtatca aacaaagtct agcctttcaa gaaggtctaa agaaacatat caaattgacc
    34621 gatgaagatt taaaaacggc ttgggaatct ttccatccag aagtggaagc tcaaattatc
    34681 caagtagcaa gtgaagatga tgcaaaagat gtgaagaaag ctgctgataa gggagacgat
    34741 ttctctaaat tagccaaaga caagtcaact gatactacga caaaagaaga tggcggaaaa
    34801 gtgaaatttg attccactac tacaacggtt ccggcagaag tcaaagaagc agcctttaag
    34861 ttgaaagatg gtcaagtttc tgatgtgatc acttctacca atgcttcaac ttatactacg
    34921 gaatattatg tggttaaaat ggtgaaaaac caaaacaaag gcaacgacat ggataaatac
    34981 aaaaaagaat tgaaagaaat tgcaacagac acaaaattaa gtgacagtac cttccagaat
    35041 aaagtaattg gcgaagtatt gaaagacgct aatgtaaaaa tcaaagacaa agactttgaa
    35101 aatgttttga gtacattcac ttcagattct agtacagcaa gtagtaaata agcggtataa
    35161 ataaaaaata tgaactattt aaatcaataa aactgttcat ctaaatcttt ttattagaac
    35221 taaatcaaca gtagtttaat tactacttga tttagttctt tttattttaa aaattttttt
    35281 tacttagaat ccagcgaccc tagatatttt tctgtataat cttaaataaa gaaaacaata
    35341 tcaaaaaatg cacgtagaag tagataaatg gagtggtttt gcaaatttct tttatttcta
    35401 gaagttattc acgtatacgg atttgttttt ctcacaaata aaaaggcagg aagtacaatg
    35461 gatcatttgt atataaaata tattcatcaa ttttccgttt tggtgttagg cacactaatt
    35521 atagcgggga ttgtcgcatt tattattcaa ggccgtgaca tattaacagt acatcaagag
    35581 tttttcagtt atgcatttgg tattcctctg atcgctataa ggtctgataa caaaaagtgg
    35641 aagaaacgct attacattct cttgctattt ttgtgttttt atctgccacc taagattttt
    35701 actttattag gtatacaatg cctatcattt tcttttattt cctatatcat tgttttaatt
    35761 ttcctcagtt tcatagtatg gatgttttat cttgtcaaaa aataaatgaa tgtttcatga
    35821 acagtacttc atcacagcct aatttttttc tttatgctat cgttatatta aagaaatcaa
    35881 tcagaaggga aagaaagtga tgaaaaaagt tttattagtg gtaaacccca gttcaggcgg
    35941 tgaacaagca aaggaatttg agcaattagc gatagcaaaa ttggaatcgg tgtttgatga
    36001 agtggtcgtc ttgcatacaa aaaaagcagg ggatgcaaaa aactttactc gcgaagcggc
    36061 tacggaaggg tatcatagtg tgtttgtcat gggcggagat ggaacagtca acgaaggaat
    36121 cagtggaatc gctgaacaag aacatcggcc aaatttcgga tttttcccat tgggtacggt
    36181 gaatgacttg gctcgagcat tagggatacc gctagaacct gaggaagcga tcaatcattt
    36241 ttcgattgaa tcagtcaagc cattggatat tggaaaaata aatgacgact attttatgaa
    36301 tgtcgtcgca attggctcta tccctgaatc aatcaatgat gtagatgcgg agaagaagac
    36361 gaaatttgga aaactagctt atttcatgtc aggaatcaaa cagttagctt ccacacaatc
    36421 ctactcgttt cacgtagaag ttgatggaaa gaaggaagaa attgagagca gtaccttgct
    36481 gataggacta actaactcag tcggcggttt tgaaacatta cttccaaatg caaaagtgga
    36541 tgatggtaag ctccatttgg tttatttaaa agattcttct ttgatcgata cgcttaaaac
    36601 attgccagac ctattaaaag gagtagatga atctacgaaa aatctagcct accttacttg
    36661 tgagcaatta gttgtgtcat tagctgatga ggaagaattg acgacgaatg ttgatggaga
    36721 tgaaggggat aaattacctg tgacaatcaa agtattgccc tcacatttac aggtttattg
    36781 ttaaaatgga ggttgtgacc gaggagttgg cgggagaaca ccgcttgttc gggataaggg
    36841 actgtgacaa gacttttgtc acagcctttt ttttgtacaa aaaagaaatt tacacctaat
    36901 agaaaaattt
//
LOCUS       DAFTHM010000020        33752 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFTHM010000020 DAFTHM010000000
VERSION     DAFTHM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.020"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            233..1894
                     /locus_tag="L7C88_000970"
     CDS             233..1894
                     /locus_tag="L7C88_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBP9557817.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(1964..2311)
                     /locus_tag="L7C88_000971"
     CDS             complement(1964..2311)
                     /locus_tag="L7C88_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBP9557818.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2395..3336
                     /locus_tag="L7C88_000972"
     CDS             2395..3336
                     /locus_tag="L7C88_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557819.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3337..4380
                     /locus_tag="L7C88_000973"
     CDS             3337..4380
                     /locus_tag="L7C88_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557820.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4386..5456
                     /locus_tag="L7C88_000974"
     CDS             4386..5456
                     /locus_tag="L7C88_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557821.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5446..6399
                     /locus_tag="L7C88_000975"
     CDS             5446..6399
                     /locus_tag="L7C88_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9557822.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6411..7421
                     /locus_tag="L7C88_000976"
     CDS             6411..7421
                     /locus_tag="L7C88_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9557823.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7706..8527)
                     /locus_tag="L7C88_000977"
     CDS             complement(7706..8527)
                     /locus_tag="L7C88_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBP9557824.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8624..8902)
                     /locus_tag="L7C88_000978"
     CDS             complement(8624..8902)
                     /locus_tag="L7C88_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557825.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9170..11179
                     /gene="metG"
                     /locus_tag="L7C88_000979"
     CDS             9170..11179
                     /gene="metG"
                     /locus_tag="L7C88_000979"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBP9557826.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11658..12245)
                     /locus_tag="L7C88_000980"
     CDS             complement(11658..12245)
                     /locus_tag="L7C88_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557827.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12420..13742
                     /locus_tag="L7C88_000981"
     CDS             12420..13742
                     /locus_tag="L7C88_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9557828.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13897..14673
                     /locus_tag="L7C88_000982"
     CDS             13897..14673
                     /locus_tag="L7C88_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBP9557829.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14666..15235
                     /gene="rnmV"
                     /locus_tag="L7C88_000983"
     CDS             14666..15235
                     /gene="rnmV"
                     /locus_tag="L7C88_000983"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBP9557830.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15228..16112
                     /gene="rsmA"
                     /locus_tag="L7C88_000984"
     CDS             15228..16112
                     /gene="rsmA"
                     /locus_tag="L7C88_000984"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBP9557831.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16563..17192
                     /locus_tag="L7C88_000985"
     CDS             16563..17192
                     /locus_tag="L7C88_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557832.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17316..18425)
                     /gene="ugpC"
                     /locus_tag="L7C88_000986"
     CDS             complement(17316..18425)
                     /gene="ugpC"
                     /locus_tag="L7C88_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBP9557833.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18634..19056
                     /gene="mgsA"
                     /locus_tag="L7C88_000987"
     CDS             18634..19056
                     /gene="mgsA"
                     /locus_tag="L7C88_000987"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBP9557834.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19379..19915
                     /locus_tag="L7C88_000988"
     CDS             19379..19915
                     /locus_tag="L7C88_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBP9557835.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(19955..21718)
                     /locus_tag="L7C88_000989"
     CDS             complement(19955..21718)
                     /locus_tag="L7C88_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557836.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21721..23436)
                     /locus_tag="L7C88_000990"
     CDS             complement(21721..23436)
                     /locus_tag="L7C88_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9557837.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24215..24439)
                     /locus_tag="L7C88_000991"
     CDS             complement(24215..24439)
                     /locus_tag="L7C88_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557838.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24630..27407
                     /locus_tag="L7C88_000992"
     CDS             24630..27407
                     /locus_tag="L7C88_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBP9557839.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27488..27907
                     /locus_tag="L7C88_000993"
     CDS             27488..27907
                     /locus_tag="L7C88_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBP9557840.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27919..28389
                     /locus_tag="L7C88_000994"
     CDS             27919..28389
                     /locus_tag="L7C88_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9557841.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28406..29185
                     /locus_tag="L7C88_000995"
     CDS             28406..29185
                     /locus_tag="L7C88_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9557842.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29172..29993
                     /locus_tag="L7C88_000996"
     CDS             29172..29993
                     /locus_tag="L7C88_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBP9557843.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30010..31059
                     /locus_tag="L7C88_000997"
     CDS             30010..31059
                     /locus_tag="L7C88_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBP9557844.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31072..32076
                     /locus_tag="L7C88_000998"
     CDS             31072..32076
                     /locus_tag="L7C88_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBP9557845.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32709..33728
                     /locus_tag="L7C88_000999"
     CDS             32709..33728
                     /locus_tag="L7C88_000999"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBP9557846.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        11028 a         5983 c         6898 g         9843 t
ORIGIN      
        1 atggcaataa tagacaatat aacgaaaatt atttaatggc ttttggaaga ccatggaaaa
       61 ccttgtacaa agctattttt tctgaaaaat tccttgaaac ctcacgaaaa aatcattatt
      121 ttatgaaaaa gacaaaaaaa agtgttgatt ttttaataat tattcattaa actcttaaac
      181 aacttcagaa aatattaatt attctgaaaa ttccaataaa ggggtacgta aaatgaaaaa
      241 gaaatttaca tttggtttgg ttgcggtatg cggccttgta cttgctggat gttatggcgg
      301 cagttcagcc acaagcagta gttcagcaaa aagcggttca gcagatggag gaggcgtatt
      361 taacttagtc gtgcctcaag aaatgcctac agctgactta tcagttgcaa cagatacaat
      421 cagttttaca gcattgaata acgtttatga aggaatttac cgtcttgatg aagacagcaa
      481 accacagccg gcaggagcta gcgagttggc agaagtcagt gaagacggat taacttacaa
      541 aatcaaatta cgagaagacg caaaatggtc aaatggtgat cctgttacag cagcggatta
      601 cgtttatggc tggcaacgaa cagtagaccc agctacagct tctgaatatg cttacctgta
      661 tgcgccagtt gaaaatgcag aagacattac agctggaaag aaagataaat cagaactagg
      721 gatcaaagca gttggtgact atgaattaga aatcaaattg acgaaacaaa caccatattt
      781 ccaatatctg cttgctttcc catcattttt cccacaaaaa caatccgtag tggaagaaaa
      841 tggggatgcc tatgcatctg caagtgataa agctgtttat aatggaccat tcacattaga
      901 agattttgat ggaccaggaa cagatacaga atggacttat aagaaaaatg atcattactg
      961 ggacaaagat acagtaaaac tttctgaaat caaagtcagt gtagtaaaag aatcttctac
     1021 tgcattgaac ttattcaaag atggccaagc agatgacgtg atcttgtctg gtgagttagc
     1081 acagcaaaac gcaaacgatc cagcttatac ttctgttaaa gaagcgcgga caagctatat
     1141 cgaattcaat caacgtgaaa agaattcacc attcaacaat gtgaacctaa gaaaagctat
     1201 ttcttattct atcgatcgtg aagctttagt aaaacaagta ctaggtgacg gatcagttgt
     1261 ctctacagga ttgatcccat cagatatggt aaaaagtcca acaacgaacg aagactttgc
     1321 aaaagaagct ggaaaattag tttcttatga caaagataaa gcaaaagaat attgggaaaa
     1381 agcgaaaaaa gaattgggcg ttgattcttt agaatttgat ttgatggctt ctgatgatga
     1441 ttcatcgaaa aaagtaatcg aatatgttca aaactcaatc caagaaaact tggatggcgt
     1501 aacagtcaaa ccaacacctg ttccattctc tgtacgtctt gaccgctcaa cttcgggtga
     1561 ttttgacgca gtactaggcg gatgggctgc tgactatgca gacccaagca gctttactga
     1621 tttgtttgtc acaggtaatt catacaaccg tggtcgctgg agcaatgcag aatatgacga
     1681 agcagttaaa gcagcttcat caacagacgc tggcgatgaa caagcccgtt gggatgattt
     1741 ccaaaaagca atcaagatca tctctgatga tatgggtgtc gttccggtgt accaaaaagc
     1801 agaaggtcac ctagtgaatg aaaaaatcaa aggtatcgtt caccatgcgg caggcgcttc
     1861 atgggattac aaatggacat acgttgaaga ataatcgtta ataccgtgag catgagaaaa
     1921 aacgaggctg cggcaaatgt cgcaacctcg ttctcatatt cacttatcct aacaaagaaa
     1981 aaagcatgaa aatagcagaa agagcaatta gtattccggc aatgatcagc caaaagctgt
     2041 acataccgta gctggcagac gagagcgagg aaaattctgg ttttttcttt cggttccttg
     2101 ttcgtgcaag atggaccgat cgctgaaaat gatcgaagaa acccgaagaa aagacccata
     2161 aaaaaccgcc gataatcaga aacggcaatg accataagaa tagatcatta gataattgaa
     2221 tgagtgtaaa ggaatggttg atgagatttt ttattaaaat aaccagaatc agtagaaaag
     2281 ctactgcgta ggggatagat ttttttttca tttgattgct cctttatttt tggttcatta
     2341 tctaataatg tagcgaaaca tctgtcagaa gtcaaaagct agggggaaac attagtgaat
     2401 agttatatca aatatgtatt aaaacgtgtc tttttcatga tcatcacgct ttggttaatt
     2461 gcaacaatca cctttttctt gatgcaattg ctgccgggca cgccatatac gaatcaggaa
     2521 cgtttgagtc ctgaaacaat cgagatgcta aataaacaag tcggtttgga taaaccagtt
     2581 atcgtacaat atgggattta tctttctaat ttgcttcaag gagattttgg aatttccttc
     2641 caatttaaaa accagccagt cgcacatttg ttagctggaa gaatcggacc atccttgcag
     2701 ttagggttac aggcaattat ctttggaaca gtcctaggga cgattttagg aacgatctct
     2761 gccatgaagc aaaatacatg ggcagataca tcttctacac tcgtagcgat attaggtcgt
     2821 tccattccaa actttgtatt tgctgtttta ttacaatata tctttgcaat caaattacaa
     2881 gttttgccaa tcgcaaaatg ggatggcttt gtgtacacaa tcttaccaac aattgcgttg
     2941 gccatgtcgc cgcttgctga ctctgctcgg tttatccgta cggaaatggt ggaagtactg
     3001 catagtgatt atgtggaatt agcaaaagca aaaggattga gccgttggga aatcgccttt
     3061 aaacatggtc ttcgaaatag tttgattcca ttgatgactt tattaggacc gttagctgta
     3121 gcattgatga ccggatcact ggtggtagaa aatatctttg ctattcctgg tatcggggaa
     3181 caattcgtta agtcaatcac aacaaatgat tatcctacga tcatggctgt aacgatcctt
     3241 tactcattta tgctgatttt tgttattttg atcgtggatc tattgtacgg tctagttgat
     3301 ccaagaattc gtgtttcaga agggagccga ggataaatgg aaatgatacc aaagcgttat
     3361 gaaacagttg cagatatccc tgcggatgaa tttcttccat tacaaaaaaa taccgaagaa
     3421 gaacgtgaac agattactgc accttctttg aattttatcc aagattcatg gcgccgttta
     3481 aagaaaaaca aagctgccgt tatttcaatg gttttactat tggtcatcat tttgatctct
     3541 gtgatcacaa tctttgtttc tcctcatgat ccaactgccc aaaacgtggc ttatatcaat
     3601 ttgcctcctc gtattccggg aatcaatatc gatggattga atggaaaagc aatggttggt
     3661 ggtgaacttg ttgataaata tgctcaagca aacgtccctt caaacgtaaa tttcttttta
     3721 ggaacagacg gtttgggacg tgatgtatta agccgcttat ttatgggaat gagaatctcg
     3781 ttgctgatcg catttattgc tgcattacta gatgtaacga ttggtgtagc ttacgggttg
     3841 gtttctggtt tgttaggcgg acgtgtcgat aacgtgatgc aacgtttttt ggaaatctta
     3901 tcaggaattc caaacctcgt tgtcatgatt ttgatgttgg tcgtttttga accaggaatt
     3961 ttttcaatcg tggctgctat ggccatcaca aactggatac caatggcacg tatcgttcgt
     4021 gcacaaacaa tgaaattaaa agatcaagaa tatgttttag ctggattgac attaggtgaa
     4081 tcaagaatga aaattgcatt caaacatatt ttgccgaata tctctagtgt cattattatt
     4141 caaatgatgt ttagtattcc atctgctatt ttcttcgaag cctttttaag ctttatcggt
     4201 ttaggtctta cgcctccgtc agcttcatta ggaacgatgt tgagcgaagg gtacaagaca
     4261 ttcctgtatc tgccttatct attatggatt ccggcagtaa ctttatcggt tatcatgatt
     4321 ggctttaact tacttgctga tggattgcgt gatgcctttg atcctaaaat gaaagagtga
     4381 agacgatgac gaaaatttta gaagtgaaag acttagaaat ctcttttgat acgtatgctg
     4441 gaaaggtacg agcgattcgc ggtgtcaatt ttcatttgaa taaaggagaa acattggcga
     4501 tcgttgggga atctggaagt ggaaaatcag tgacgaccag aagcatcatg cgcttgctgt
     4561 caagcaacgc caatatagat gctggtcaaa tcctctttaa aggtaacgat atcgttggaa
     4621 aatcagaaag agagatgcaa aaaatccgtg gtaaagaaat agcgatgatt ttccaagatc
     4681 caatgacctc tttagatccg acgatgccca ttgggaagca agtcgctgag tcccttagaa
     4741 agcataataa agtttcaaaa aaagagggac aaaaagctgc attagaattg cttaaattag
     4801 ttggaatacc cgaagctgag aaacgtatca acagttatcc gcatcagttc tcaggaggtc
     4861 agcgtcaacg gatcgtgatc gcgattgcac tggtatgtta tccggaaatc ctgattgctg
     4921 atgaacctac aacagcgctt gatgtgacta ttcaagcaca gattttggag ctgctgaaag
     4981 aaattcagac aaaaatcgat acatcaatta tctttatcac tcatgacctt ggtgtagtag
     5041 cgaatgtcgc tgatcgtgtc gctgtcatgt atggaggaag aatcgttgaa gttggaacat
     5101 cggaagaaat tttctacaac ccgcaacatc cctatacttg gggactgctt ggttcaatgc
     5161 cgacattaga tagtgcgaac gatcgattgt atgctattcc tggttctcca ccggatttat
     5221 tgaacccgcc aaaaggagac gcattctatc caagaaatga attcgcgatg aaaatcgatg
     5281 cagaacaaga accaccattt tttgaactat caaaaacaca caaggcagca acttggctac
     5341 ttgctccgca ggcacccaaa gtgacaccgc cagaagaaat ccaacgtcgc tgggctatct
     5401 ttaaagagaa acaaaaacat acttacggtc aaggaggaat tgctgatgcc aaataaacta
     5461 cttgaagtta aaggattgaa acagtatttc aatgtaggaa aaaagaatga agtacatgct
     5521 gtaaatgaca tcagctttca catttatgaa ggagaaacat tcggtttagt tggagaatct
     5581 ggaagcggaa aatccactac tggccgtacg atcattcgct tgaatgaacc tactgatggt
     5641 gagatattat tcgacggtca agatataacg aagatcaaag ataaaaaagg tttgacgaaa
     5701 ttccggcatg atgttcagat gatctttcaa gatccatacg cttcgttgaa tcctcgtatg
     5761 aaagtcagag atatcattgc cgaaggaatt gatgttaatg gactagctaa atcatctgaa
     5821 gagcgtgcaa aaaaagtcga tgatctattg agaactgttg gattgaatcc aagccacggt
     5881 actcgttatc ctcatgaatt ttcaggtggg caacgccagc gtattggtat tgcacgagca
     5941 ttggcagtaa aaccgcgttt tatcatttgt gatgaaccaa tttctgcact agatgtgtcg
     6001 atccaagccc aagtggtcaa tttgttgcaa gatctccaaa aagaacatca attgacctat
     6061 ctatttattg cacatgattt gtcgatggtt aaacatatta gtgaccgaat cggtgtaatg
     6121 cataacggct tgttattaga gatgggaaca agtgatgaaa tctataatca cggtgttcat
     6181 ccttatacag aaagtttgtt atctgctatt cctctaccag atccagacca tgagagaaaa
     6241 cgcagaagaa tcaaatatca acctgaacca gatgacggac aagtacgtca acttcgtgaa
     6301 atcgcaccag aacattttgt ctatgcaact gagcaggaag tcccatatta cgcaaaaaaa
     6361 ctaaaacgac aaaaggaatc tcttctggtt gctaactagg agggacatag atgctaaaag
     6421 cttttaaatt ccgtatgtat ccgacagaag aacaaaaaca gcaattgatt cgtacttttg
     6481 gatgtgctcg atttacctat aaccatttgc tgaaaaagcg gcagaaaagt tggcaacaaa
     6541 caggagtagc caatttttcg ctcacacccg ctacattaaa aaaagaatac ccattcttaa
     6601 aagaagtaga cagtcttgct ttagcaaatg cacagcttaa tttggatcgg gcttttcgca
     6661 attatttcaa gggacgtgcc agcttcccaa agcttaaaac gaaaaaaagt atgtggcaat
     6721 cttatacgac caacaaccaa acccgtacga tctatctgga aaatggctac ttaaagttac
     6781 caaaacaaaa agaactaatc aagataaatc agcatcggcc agttgaagga tcgattcgct
     6841 ccgctacgat ttctgctcga tataatgaag aattttatgt cgcactactt tgtgatgttt
     6901 cgccagtaaa aaaagaatct ttagctaaat ggatcgggat cgcctatcat ccgaagacat
     6961 tgatccaaac atctcgacct ctagaagtaa ctttaccaaa atttcaccag acagaagaaa
     7021 agctgcaaca tgcacagcgg aaattgaatg tgaaagtccg ctccgctcac catagaaaga
     7081 tcaggttaga tcaggcaagc aattatcaga aacaaaagag aaaagtaatg gatctttatc
     7141 tgaaacaaaa gaaccagcga gaagattatc ttgaacaatt atctgggaaa ttggtcaaac
     7201 aatatgacta cttatttgta gaatcttttc caaaagaaga ggcacatgct gatttttcta
     7261 ttcacgactg gcataaatta ataacaaaat tgcgttataa gtcccaatgg tataataaaa
     7321 aatttctttt gatcaatacc gacggagcag aagaaagcaa ttccgtaaga aagagccaag
     7381 tagtagaaaa aatgggcaga cattcggtta tcaagggata aaaaatgaat gaaactgata
     7441 ggagcgttag ggttagcctt gttaataaaa agtcttaatg acttttgttt ctaggaattt
     7501 ttcttttgaa gaaaagctca ctaattatga caaaccaata aaacaatagc agaaaaagtt
     7561 cgtacgagct ttttctgcta ttgttaattt tttattcaga aagtttacga atacatcaaa
     7621 attctgaaac aaaaaacgta actcacaaag agttgttttt gcgttttttc ttgaatgatt
     7681 aggtctgaat cttttgctca caaccttatt catggtgccc cggcttgagc tgatagattt
     7741 ttgaaggacg gccgattcct acaggacgtt caccgatctc atcgaaatat tggagcatag
     7801 ctttcttaaa attggaatga tcgatcgttt tataatcgat ccctaagaat ttagcaaata
     7861 cttttcgagc ttccgtaatc gtgaaatctt tacctaaaac ttgtagaact tgcggctcgt
     7921 gttccatttt attgactaca cggttgaatg ctttcaagat gatttgacta tggtcaaaag
     7981 ccaaagtatc tttgccagaa gactctccag tgactaaatc aagcgagata gccacttctc
     8041 cgctagataa atggatcttg ttactatgac gttctagtgt gaaccagcgt acttccttgg
     8101 catcatctcc ggcgattagc ggttcttctc caataaaggc taagtagctg actgtgacga
     8161 cccagcctcg cggatctcga ttaggcgtac tgaatgtatg cagttgctca atattttctt
     8221 ttgaaataac cacaccagtt tcttcctttg tttctcttaa gacgctttct ccagttgact
     8281 catccttttg gacaaagcca ccaggcaatg cccatgaatt tcgataagga tgcccttttc
     8341 tttggatcaa caaaactttc agctgatctt cttctttgtt atagcacatc agtacgatat
     8401 cgacagtcaa agagggcttg tcatattctg gacgttcctg tttttgatac cagttaagaa
     8461 attcttcttc acttgcttta tgttcataat ataatttttc ttcttcttta gaagcaaaac
     8521 ggttcatctg accacctcca ttgacagtaa aagtactttt taccttattg tagcagactc
     8581 tgaaaaaaaa ccaaggattt acttgaaaaa tctaggttat catttaaata tgaaaaataa
     8641 atggaagtat gagattgaat aaaaagaaaa gcagataaaa cggcaatact ttataccgct
     8701 cttcacgaat ggcaaagaag ccacaaataa cgatatatac gtcaatgata aaacgcaaaa
     8761 tccaagctgc tgtcataaaa ctgttcaaat gcccatggag gttaaaataa ccatacatac
     8821 gaatataaaa atagctgaat attaaatgtg ctaatgaaag aaaagcaata ctaagtgtaa
     8881 aaaaaagatg tttcttctgc atgattgttc cagtccctta ctaagataga tagtctttat
     8941 tataccacgt gtgaggggag aaataaaaag ccgtttttta gtagatatga aacaaaacaa
     9001 aaacccgcat ttattcaacc tattcatcct tttaaaggat agattgaacg tagatagaag
     9061 tcgtttatcc agtctttttc attttgaaaa aaagctaaca gcatgctttt tttatggtat
     9121 actagcaagg aaacgaattc gcatcatgcg ataaaggagg aagagccccg tggcagaaaa
     9181 ggaaactttt tatatcacta cgccaatcta ttatccaagc ggcaaacttc atatcggcaa
     9241 ctcgtatact acgattgcat gtgacgcaat tgctcgttat aaacggttga tgggctttga
     9301 tgtgttttat ctcactggag tggatgaaca tggtcaaaaa atcgaaacaa aagcagaaga
     9361 actaggtgta aaaccgcaag aatatgtaga taaaatggcg gctgatgtca agaaattatg
     9421 gaaaacgctt gatatcagtt atgataaatt cattcgcacg acagatgatt accataaagc
     9481 agctgttcaa aaaatatttg atcgtttatt agaacaggga gatatttact taggtgaata
     9541 tgaaggctgg tactctgttt ctgacgaaga attctttaca gaaacacaac ttgcagaagt
     9601 gtacaaagat gacgaaggta acgtgatcgg tggtaaagcg ccaagtggac acgaagtaga
     9661 attggtaaaa gaagaatcat acttcttccg catgagcaaa tacgcagacc gtctattgga
     9721 atactatgaa gaacatcccg aattcatcca gccagaatct cgtaaaaacg aaatgatcaa
     9781 caactttatc aaaccaggat tagaggatct tgcagtttca cgaacaactt ttacttgggg
     9841 agtaccagtc aagagtgatc cgaaacatgt ggtgtatgta tggatcgatg cattatccaa
     9901 ttatattact gcactaggat atggctccga agatgaaagt ctattcgaaa aatactggcc
     9961 tgcagatgtt cagatggtcg gtaaagaaat cgttcgcttt catacgatct attggccaat
    10021 catgctgatg gcccttgatt tgcctctacc taaaaaagta tttgggcatg gctggctatt
    10081 gatgaaagac ggaaaaatgt ctaaatcaaa aggaaatgtc gtttatcctg aaatgcttgt
    10141 ggaacgttat ggtttagatg cactccgtta ttatttgctt cgtgctgttc cgtttgggtc
    10201 agatggtgtc tttacgccag aagattttgt ttcccgtgtc aattatgatc tggcaaatga
    10261 tctagggaac ttattgaatc gaacgattgc tatgatcaac aaatattgtg atggactcgt
    10321 tcctgactat gcctcacttg tcactccatt tgatagtgaa ctgtctacga cggctgctaa
    10381 cgttgtcgga cgttaccatg atgcaatgga aaaaatggaa ttcaatacag cattggctga
    10441 aatctgggtg ctgatttctc gtgcaaacaa atacattgat gaaacagaac catgggtatt
    10501 agcaaaagac gaagaaaaga aagctgaatt gaatagtgtc atgatccatt tagctgaatc
    10561 tttgcgtatc gcagcgatat tacttcagcc aatcatgaca gaaacgccag agaagatctt
    10621 caatcaacta ggattggact ctgaaacaat gaatcttgaa ggattacact ttggcgaatt
    10681 tccttcagga acaaaagtag ttgcaaaagg tacaccaatc ttcccacgtt tagatatgga
    10741 agaagaagtt gcttttattc aagaaaaaat gtctgaaggt actcaaacaa acgaagatac
    10801 agtcaaatgg gatccagaag aaacagaact tgtttcaacg aaagaaaaac aaatcaaatt
    10861 tgatgtattt gaaaaagtag aactaaaagt agcagaagtc atcaactgtc aaaaagtaga
    10921 aggggcagat aagttgctgc aattccgact agatgctgga gacagccaag accgtcaaat
    10981 cttgtcagga atcgctgaat tttatcctga tccaagcgaa ttgatcggga aaaaagtcgt
    11041 cattgtagca aatctgaaac cacgaaagat gcgtggacaa atcagtcaag gaatgatcct
    11101 ttctgcagaa gcaccagatg gctctttaca agtaatcgaa gcaccaaaat ccatgccaaa
    11161 tggctcagaa atcgcataga aattcaaagg gggtatgaca ctagttgtgt cataccccct
    11221 ttttccgaaa tttgagaagc aattttcgta aattccttct tattacttga agccaatcat
    11281 ataatacaga aacagagaac tatccaaaat aaatcctaga aaaagaagta cgagcttcgc
    11341 tgatttttgt taatttagaa taatactaat aggaatcgta aaaacagaaa aaaagcataa
    11401 tgataaaggg tcgggcagat tttaattgat tcatctggta ctctttttta ttgtccttac
    11461 attcataaag tttgaatgca atgactttat tacatctata tttatatcta acagtagcgt
    11521 tgatgtgtta attataagtt ctatcacttt atgttcaatt agtttgtgct cttatatgtg
    11581 tgattgaaaa tatagataaa aaaacaatca tcggctttga cttcgatgat tgttttcttt
    11641 attttgtaaa aatcctatca cttgatttta tggtaacctt ttatttttgt cttcaaacgg
    11701 cttggtaaga gagcagtaag cagtgcaaat gggatcgaaa agacatacca gaaaatcgta
    11761 cgtccgatac cataatgttg atagagcttt gtcaacatca cgtgtaacaa gatcaaccct
    11821 aaaagcaagg agccagctat aaaccaatga ttatcccaat gcatgacttc actaagtgcc
    11881 atcactccaa aaggatagaa ataaaaatag atcccgacta aggtcatccg ccagttcttt
    11941 gtaaatgttc cgatattcaa taaaaagaaa atcgctgaaa gcaaaatacc gataggcgga
    12001 aaaagcccaa ccaaaaagga atacaacatc ccccacaaga tcatcacagg acctttgatc
    12061 aatgcaacga ttgcgatgaa caaagtcagc aatattagtt tttgtgataa cgttgcaaca
    12121 gtcattaatc caaataaaat taatgtgaac caatgccaat gggactgctg ttgttcttta
    12181 cgggaaaaat cgacccggtt ggataaataa tctgctaatt tcggataaga acgcttaaaa
    12241 tccataaact gttcctcctt cgtggaaaag gtaggtttag tatacgaaaa ataaaaaaga
    12301 aatacatccg tcttaagagg gagtttttca ctgaaagtgg agaaaaaaga atggtaaatt
    12361 aaaatattct cagttatact gaaaattata ccaaatttca aagaagaaag aggatgggaa
    12421 tgaaaggcaa actaaaacga gaaatcaatc tgtttggcgc attagctacc gttatgggaa
    12481 ccgtgatcgg tgcaggcgtc ttcttcaaaa ctgctgctgt tactgctagt actcagtcta
    12541 caagtttgac attgctagct tggcttttgg gtggtttctt aacgatctgt gctggattga
    12601 cagtggctga attagctaca gcaatcccgg aaactggtgg agctgtaaaa tatattgaag
    12661 ctgcgtatgg aaaattgccc agctttttat taggatgggc gcaaagcttg atttactttc
    12721 ctgctaatat tgctgcatta tcgattatct ttgcgacaca attgacgaac ttattacaat
    12781 tatctaccga ttatcttttg ttgattgcag tgatcaccgc tgtttctgtg acagggttga
    12841 atttgttagg gacaaaagtc ggtgcttctg tacaatcagt gacgttgatt gttaaattaa
    12901 taccaattgc tgtgattgtc atatggggat tattgacccc aggacaagga actgtccagt
    12961 tatttccaat cgaagctgga aaagatgtta cttttgtcga aggattgagc agtgcgttgt
    13021 tagcaacgtt gtttgcttat gacggctggt taggtgtcgg tgcaatggca ggggaaatga
    13081 aacggccgga aaaagatttg cctaaagcaa ttattcttgg tttgagtttt gtaacagtcg
    13141 tttatctatt gatcaatttt gtttttttga aaactttgcc gattgatcat cttgccggta
    13201 atttgaatgc agcttctgaa gcatcagacg tcatttttgg aggaatcggt ggaaagctgg
    13261 tcactattgg gatcttgatc tcggtatacg gtgcattgaa cggttataca ctaactggga
    13321 tccgcgtgcc ttatgcgatg gctttagaag acgagctacc tttcagtaaa cagctgacaa
    13381 agctttcaaa gaagtttacg gttccttatg ttcctgcggt tttccagtta gcagtagctt
    13441 gtattatgat gagccttggt tctttcgact ttttaacaga catgttgatt tttgtgatgt
    13501 ggctattcag tttactgatt tttatcggtg tctttatttt aagaaaaaaa gcgccggaat
    13561 tgccacgtcc atataaagta ccactttatc caatcgttcc gattattgcg attctcggtg
    13621 ctattttcat tttaggtatg acgatgatga cgcaaacgaa attagcattg atcggtatag
    13681 gtgttacctt gataggtatc ccagtctatt atcaaaaaaa gaaaaaacgc tcagaagagt
    13741 aaaatatttc aacaacagac agaaaaagta cgaactaggt cctctagatc ttcgtgcttt
    13801 ttctatttca ataaaacaag ttcttctatt ttgatttttg ctacttctgc aagtagtgct
    13861 tatgtgctaa agtaagaatg aaaaggagag ataaacatga tatttgattc tcatacccat
    13921 ttaaatgctg aacagttcaa tgaagatatt ccagaaacga ttcagcgagc acaagaaatg
    13981 ggggtaacga aaatggcggt cgtgggcttc gatacgccaa cgattgaaaa gtctttgcaa
    14041 ttaagccatg actatccaaa tatatacagt attatcggct ggcatccgac agaggctggc
    14101 agttatacga aagaaatcga aaataaatta caagaacaat tgactttacc aaaggttgta
    14161 gcattagggg aaattggctt ggattatcat tggatggaag acccgaaaga agtccaagat
    14221 aaagtatttc gcagacagat tgctatcgca aaagaaatga acctaccaat cagtattcat
    14281 actagagaag cacttgaaga cacgtatcaa atcctaaaag aagaagatgt tcgagatatc
    14341 ggtggaatca tgcatagttt cagtggtgat tatgaatggg caaaacgatt tcttgactta
    14401 gggatgcata tttcatttag cggtgtcgtc actttcaaaa aagcattaga cgtccaagag
    14461 gctgcagcaa atgtaccaat cgaacgatta cttgtggaaa cagatgcccc ttatctggca
    14521 ccagttcctt ttagaggaaa gcgaaatgaa ccaggctata ctcgttatac agtagaaaag
    14581 attgctgaac ttcggaatct tccgacagaa gaagtggctg cccaaacatg gacaaatgcg
    14641 caccgattat ttggtctaag cgaacatgga taagatgaag atccaagaga ttatagtcgt
    14701 tgaaggaaaa gacgatacaa gaaggctgcg ggaagtagtt gatgcagata cgatagaaac
    14761 aatagggtct gcaatcaatg aagagatcct gatgcaaatt gaacatgccc aagagactcg
    14821 tggagtgatc gtttttaccg atcctgattt ttcaggagaa aaaataagaa aaatcattat
    14881 ggaagctgtt cctcaggcaa aacatgcttt tttgccgcgc acacaagcta aaccaaagaa
    14941 aaagggaagc cttggtgtcg agcatgcaag tgatgctgct attttagaag cattgaaaaa
    15001 ggtcgtgacg ccagacattt cccaaacggc tgtttctgaa atcactagac aagacctttt
    15061 agactatggt ttaatagctg gggcacaagc aaaagaaaaa cgagaaaaac taggtgacga
    15121 gttgcgcatc ggttacacga acggcaaaca attggaaaaa cgtttgaaga tgtttcgtat
    15181 tacgccgaaa gaactcgccc aagcaatgaa aatagtggag gaacaacatg agtgaatatc
    15241 gtgaaattgc gacaccctct agaacaaaag agattttatt gaaacatggt ttttcattta
    15301 aaaaaagttt aggacaaaat tttctgactg aaccaaatat tttaaggaaa atcgtagaaa
    15361 ctgcgcaaat agatgaacat acgaacgtga tcgaagttgg accaggaatc ggtgcattga
    15421 cggaacaatt agccaagcat gcaaaacaag tcgtagcatt tgagatcgat gatcgtttga
    15481 tccctgtatt ggctgatacg atgcaaccct atgacaatgt gactattgta catcaagata
    15541 ttttaaagac cgatttgtca acagctgtta gagaaacatt tcatgaggag cttccgttaa
    15601 aagtcgtagc gaatttacct tactatatta cgacaccgat catgatgcat tttcttgaat
    15661 cagatttggt tgtggatgaa ctagtcgtca tgatgcaaaa agaagtagct gatcgtatct
    15721 ctgctgaacc aggaacgaaa gcttatggtt cattatcgat tgctgttcaa tattatatgg
    15781 aagccagttt agcattcatc gtaccaaaaa cagtatttgt ccctcagcca aatgtagatt
    15841 cagcgatttt gaaactgaca agaagagata taccggcagt cgaagtgaca gacgaaaaag
    15901 catttttccg attgacaaaa gcggcatttc agcaaagaag aaaaacgctt tggaataact
    15961 tgcagcattc gtatggcaaa gatgaccaga caaaagcatg gttagcaaaa agcttggaaa
    16021 cagctggaat cgatccaaaa cgtcgtgggg agactttgtc attacaagaa ttcgccgcat
    16081 taagcaatgc gatgtcagaa aatatgcagt aaaaaaagag gttgtgacag aagttgtgaa
    16141 aaagctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagttcct catgtttttc
    16201 gtttgtttgg gcttgttacc gcagatgcaa gcttttgaac accgtttaag aaagaggttg
    16261 tgggcctgcc gtttaactct aagtcacaag gaacaatttc aaaaaacagc ttctcatgtt
    16321 tttgagttag ttggtcttat tacttgatgc aagcttttga ccactattat gccgaacaag
    16381 gagatgtgac acaaattttg tcacatctcc tatttttgtt tcttgatcaa aaaattctta
    16441 tacttgatac tcacactcat tttgtatgga tttagaaaag aatatgtgtc ttgacagtta
    16501 ttagtaagtg agttatacta agtcgacatt tatgtgtcaa gacatattag gagagagaaa
    16561 aaatgagaaa aaattcagtt cgaaaactaa cgatttctgc tttattgatt gggatggggg
    16621 tcattatccc aatggtcatg cctaaaatca tgattccacc agcttccttt actttggcgt
    16681 ctcatgtgcc attatttatt gcgatgtttt ttacaccagg agttgcagtg gctgttgcgc
    16741 taggtacgac atttggtttc tttttaacaa cgccggttat catcgcattg cgagcattgt
    16801 cacatcttgt gtttgcgttg attggggctt ggtacttgca aaagcatccg agtatcgttt
    16861 taaaaaatgg acagtttact tttgctaatt ggcgtttcca agggttcaat tttgtgatcg
    16921 gtgtgattca ttctttagca gaaatgctag tagtcagcat cttttacttt attggtaata
    16981 tgcctgaaac atattattct caaggatatt tttatacagt attcatcttg atggggattg
    17041 gtgggcttat ccacagttta gttgattata atattgctta ttttatagca ggaacactca
    17101 gcaaatattt tgatatcccc gtatttacgg cagcaaaaaa agaaaatcgg aaagagtcga
    17161 ttcaagggta cgcgaagaaa acgacatatt agacatgatc tctcaaaaaa aaaactctca
    17221 tctagtaatg gataataaat cctctaagat gagagttttt tgtcctaaaa agagctgcac
    17281 caacatcttc tggcacagct ctaacagggg gcaatttatg gaagtttgat gacttgttct
    17341 gtttctttat caaagaagtg gcctttgctg atgttgaagg caaggtcgac tatttcgcct
    17401 ggtttatgga aatctcttgc atctactttt gagatgaact cagtagaacc agtttttgtg
    17461 taaagcatcg tttcagctcc aagtaattcg gaaacgacaa cttctgattt cactacggct
    17521 tcaggtgaag cttcaagggc tacttgttca ctgtggatgt cttctggacg aataccgaag
    17581 ataacttctt ttccttcata acctttttca actaatactt tgttttttcc ttcaggaata
    17641 cgaagcttaa gcccatgtcc atctgtgata acaccatttt tcaatgtcac attaaagaag
    17701 ttcatggcag gagatccaat aaagccggca acgaacatat tgacgggtgt atcataaact
    17761 tctttcggtg taccgatttg ttggataaat ccgtctttca tgataacgat tcggtcagcc
    17821 atagtcattg cttctgtctg atcgtgagta acatagatgg tcgttgtttc aagacgctgg
    17881 tgaagtttgg caatctcagc acgcatggct acacgtaatt tagcatctaa atttgataat
    17941 ggctcatcca ttaagaagac ttttgcatcc cgaacgattg cccgtcccaa tgccacacgt
    18001 tggcgttgtc caccagataa agcagctggt tttcgtttca agtattctgt cagacctaag
    18061 atctctgctg cattgtccac acgttttttg atgtctgctt tatcatattt acgtaatttc
    18121 aagccaaaag ccatattatc aaaaacagtc atatgaggat acaatgcgta gttttggaaa
    18181 accatggcaa tatcacggtc tttaggtgcc acgtcattca tgacttttcc gccgatattt
    18241 agttctcctt cagagatatc ttccagtccc gcgatcattc gcaaagtagt tgactttcca
    18301 caaccggaag gaccaacaaa aacgataaat tcacggtctt tgattgatag attaaaatca
    18361 gttacagaat aattttctgc attgtcatat tttttatata cgtttttcag agccatttct
    18421 accataatac gttccacact ttctttttta gttttattaa ctatttaaag tataaatgaa
    18481 agcgttaact aacttcaatg tcatgttgaa caagaatttt ttcttttttt tgtcaatgtg
    18541 ctagttttaa gctttaataa atatccataa gaaataaaaa ctgatacact ggagtaaata
    18601 agtatgttaa caatatcaaa aggagtgtct cttatgaaaa tcgctttgat cgctcatgac
    18661 cgaaaaaaac ctatgatggt gaaattagca acagcgtata aaacaatatt ggaaaaacat
    18721 gaactttttg ctaccgggac gactgggcag aggatcacgg aagcaaccgg cttgccgatc
    18781 catcggttta aatccggacc gttaggcggg gatcagcaaa ttggagccat gatttcggag
    18841 gatcagttag atttggtgat ttttcttcga gacccgctgg ctgcacagcc ccatgaacca
    18901 gatgtaacag cacttatccg tttatctgat gtctatgaga ttccgttagc tacgaatatc
    18961 ggaacagctg aggtgctact aagaggactg gaagccggct tcctagattt tcgaagaatc
    19021 gtccatgaaa tagacaagca tccactttca ttttgatgga taagcgtatg gaaaaataac
    19081 gtttaatgtt cgcctatatg tagctataaa agctaaacaa actgataata tgcgatataa
    19141 tacgaacgta ttggataata taaacaataa tattagtttt tcgtatttgc agtaaatgtg
    19201 aaaatatgct atagtttctg tgggaaaaga tcccaaaaat aatacagagt agaaaataaa
    19261 gcgttaagtg ctaagaggat gggatgttgc ctcttggacg aaggacgtaa tgttcgcggt
    19321 tttattttcg cattcgctgc atgatacgat gtagcagctc ttaaaggaga tgctaaaaat
    19381 gaagaaacac cggttagacg cacgtatgat tgctattatg ggcttattga ttgcattgat
    19441 ggtcactttg tcccgactgg tagcaatcga gaccccattt attaaaatca gtgtcacatt
    19501 tattccacaa gtgatcatgg gcattctttt tggtcctttt tggtcaggga taggcgcagt
    19561 tttagctgat ttagtaggaa tggccctctt ctcgaaatct gcattcttta ttggatttac
    19621 attgaatgca tttattgaag gagcaatcta cggattcttt ttctatcgaa aagagatcac
    19681 ttggaaaaat gccattctgg ctacgcttag tgtcacgctg atcatcaact tatttttgac
    19741 accattatgg cttgcgttga tgtaccatgt gccattgttc agctgggtcg tttgggcgcc
    19801 ccgcctgtta aaaacagtaa tatggttacc gattcaatca attgccattt attacgtagg
    19861 acgtagtatt ccttacaaaa aaattttaag aagtttagcg atccacgcta aataaaaaac
    19921 aagcagtctt cccatcccag aagactgctt gtttttattg tgctgtgaat tgtgcttgat
    19981 agagccgtcg gtaataacca tctttttgaa gcagctcatc atgggtgccc atttcgacaa
    20041 tagctccctg atccatcact aatatctggt ccgcattttt gattgtggac aggcgatggg
    20101 caatcacaaa actggttttt ccttccatca ttgctaagaa ggcttgttgg atttttttct
    20161 ctgtcaatgt atcgactgag ctggtagctt catctaagat caacataggg ggattactga
    20221 tcatcgttcg agcaatcgtc aacagttggc gttgtccatc tgatatcttt aacccttgac
    20281 cgccaatctt agtatctaat ttttccggca aacgttctac aaattcatac atataagagg
    20341 cttttagggc atcattgatt tctgcgtcac ttgcttccgg attcccaaaa cgaagatttt
    20401 ctcgcaatgt actgtcaaat agccaagtat cttgtaacac cattccaaaa cttttacgta
    20461 atgtatcacg ttggatagag cggatgtcat ggtcatcgac tgtaattgtt ccttttgttg
    20521 tgtcataaaa acgcatcagc aaattaacaa gtgtggattt tccggcccct gtttttccta
    20581 ctatagcaat ggtttgacct ggataagcag taaaattgaa atcttcgatc aaacgctgct
    20641 tggggtcata agaaaaagaa acatgatcaa aagagacttt tcctttgata tttttgggtt
    20701 ccaaggcata ggcatctggc aaatcaggct tttcttctgg ctgatcgatc aaatcaaatg
    20761 ctcgttctag accagaaaaa gcggtttgca gttgtgtcgt gattccagaa agttcgataa
    20821 atggtttaga aaactgactt gagtagatcg taaagctgga aatcacacca acagtgattg
    20881 acgaaccact cttcaatgcc aataggccgc caactaaacc aatcgataaa taagcaaggt
    20941 gatctacaaa acgagaagac gggtttgtca aggaagaaga aaattgtgcc cgttgtcctt
    21001 tttcatatag atcagcattt agcagttcaa attgctgttg actagcttct tcttgctgaa
    21061 aagctttcac gattttctgg ttaccgattc gttcggtcac aaagcccgag atatccccaa
    21121 taatcctttg ctgtctatcg aaatttgttt gtgaagcacg agcaacgatc caactcacaa
    21181 ggaaaataat tggtgtagaa caaagaacga ccaatgtcag aagtggactt agacgcatca
    21241 taaaaataaa cgaaagaatg atgattgcca ctccagaaaa taattgattg aaggccgcag
    21301 aaattgcaat ggaaatattg tccatatcat ttgtaaatcg actgacgata tttccgtggg
    21361 agttttgatc ataataacga agtggcaatc gattcagatg agcaaatgca tcttttctta
    21421 attttgcaac ggataagtaa gctaaccgat tgcttaacac ttggatgagc cattgactga
    21481 ctacgttgat taaaacgata ccaccgaata gaataagtaa atggaacagt cgattgaagc
    21541 ggacctgtcc ttctccaatc atttgatcga tactttgacc aatttgtaac gtcatcacaa
    21601 ctgttgcaat cccattgatg attcctagta tcacagctag ccaaatgtct tttgcatagg
    21661 cagtaaggta aggaatgaat cggcggagcg tctgcaagga taattttttt actttcataa
    21721 ctattcttcc tcctgtgatg cgacgatttc ctgatattct gctgattgag caagtaattc
    21781 ttcatgggta ccctgagcag caatcttacc ttgatccatc actaagatat gatgtgcttc
    21841 ttgaatagag cggacacgtt gggagataat aatcactgta ctgccaagat aagtctgtag
    21901 cgccttacgc aaatccaagt ctgtttgata atccaacgca cttaaagagt catctaaaat
    21961 cagtaatgct ggcttggcaa tcaaagctct tgcaatcgtc agtcgctgtt tttgtccgcc
    22021 agagaaattt ttcccatttt ccatgacttt tgtatctaaa ccatttggaa gctgacggac
    22081 aaattcttct gcctgagcga ttttcagagc ttcccaacat tctttttctg tggcgtcttt
    22141 cttaccccat tgaaggtttt cacgaatagt cccggtaaat agtacagaag tttggggaac
    22201 aagagcaatt tgctgacgga gatgatccag ctgccaagaa cgaacatcca ttccgtccat
    22261 tataactgta ccggaactga catcatagaa acgcggaatc aattgtgtca aagtcgtttt
    22321 cccgcttccg gttggaccaa tgattccaag gactgtattt cgcttcagct gaaatgtaat
    22381 attttggaga gaaagaccag aatcaggagt ataacggaag tcaacatggt caaaagcgat
    22441 aattgcttca gaagaaaaat cgggagtagt actgacctca gcttcaagaa tcgaattttc
    22501 tgtgtctagc acctctttca cccgatttcc tgaagcttcg gcacgtgtga agatcacgac
    22561 gaggtttgaa acaacgatca gtgccaaaag catttgattc atataattga tcaaagcaag
    22621 aacttgtcct tgttgcaagc taccaatatt tactttgatc ccgccaactg tcagcaaaca
    22681 gatgatcccg acattcatga tcaaggttgt agcaggtgat aatagggcag agatattgga
    22741 aacacgtaaa taattgttcg ctagatcatt tgtgctttta tcgaacttct ctgtttcttt
    22801 ttttgtctgc gcaaatgcgc ggatgacacg aacaccgcta agattctgac taacgtgttc
    22861 attgagctga tctagttttt cttgcacttt ttggtagaga ggaacggttt ttttgatgat
    22921 aaaaaataaa atgattgaga aaataggcaa taatgctaag aaaaacagac ctacttccca
    22981 gtcgatcaca aaagccatga ccactgaccc gatacttaaa aacggtgctc tgatcaataa
    23041 acgaatgacc attgctaaag ctagctgaag ctgattgatg tcgtttgtca ttcgggtgat
    23101 caaggtatct gttccaaaat gattcaactc gttgtgagag aaagtattga tttttttgat
    23161 tagctgatta cgtaactctg taccaaatcc ttgtgaagct actgaagcat agtattggca
    23221 aatgatagca caaatcagac caatcacaga catagcgacc atccataagc ccatttcaat
    23281 gatttttcct cggtcattca tttttagtcc attatcgatc aaggaagcca tcattaaagg
    23341 caggacaagt tcgaagacag cttcaagaaa tttgaagaac gggcccaaaa tgatttgctt
    23401 acgatagtct tttgcataac gtaataactg aatcatatga ttcctcctat tatttatttg
    23461 tccacaattg aaaaaacaag tactaccaca ttgtagctta ggaaatttag aatgaaaaga
    23521 gaacaagcct tttcataaat gaaagtttta ttatgaagaa gctttagaaa ttgaatagac
    23581 tatttttttt aaaaaaaaga aaatgagaaa acatgccagt ctcttcattc ataggaacgt
    23641 ctattttact taatttttct ataaatgaat tctgcataaa aaatatatca agtaaatgtt
    23701 tatagatgaa actctattta cttctttttt aatttgttct tgcaatcttt tttgctacgt
    23761 aatttttgta aaaaagtggg ttgagagaaa tctaattgat tttcaaagaa ggagtatgaa
    23821 aatgagaaaa atatttattc gtttattgtg ggtactatct tagaggaata aataatagtg
    23881 gagaaaacta tggtttggcg cagattctat caggtttgat ggaacgaaga caacctcccg
    23941 acatcaagtc aaaagctact tgagattttg atctgaaaat aaaaaaagaa aacaaggtag
    24001 gaacatcaat gtttctacct tgttttcgta atcaatggga aaaaactaag agtggtgtac
    24061 gtaatcaata aaaaggatgg tgacaacagt acctctttac tctctgaaag catcataact
    24121 cgtttttcct cattatgcca ataaattgtt gttataccac atataaggat ttgtaatagc
    24181 taaaaacaga caggaaagtt gaaatctgtg aatcttattt tgtatggaag gatttataga
    24241 acgcaaaaat caagataaag atgaataaaa atcctgtttc ggctatatat tgcgtatcta
    24301 cgccaataaa acgagtttgt tctgtcatag ccatataaag caaaggcaaa aatacaacta
    24361 cagcgagata agatccgatg atttctcgaa aagttttcca ggaagtatgt ttcctgtttt
    24421 tatatttatc cgatttcatt gaatagtcat agcctcctta ttctttcata tgttgaaatt
    24481 ccagtataaa aactggaagg aactgtacgt tttttagaat aaaaattata agggataagt
    24541 aggctgctgt ctataataag atatattttt caattcttta ttaaagattt tattgacaaa
    24601 atgaatccgt tttctatgat ggaggagggg tgaataagtt gttgaagaag gaaattttat
    24661 gttacttaga gaaccagaca gcctttttcg atttagaaca tatgaacgag gtctttacag
    24721 cacaaaggtt agctgatcat tttggggtaa aaagaaacac agtcagtcat tatttgaacc
    24781 agttaaatga tgagcaacta ctagtcaaaa tcaattctcg accagtgatt tatttccaca
    24841 aagaagcttt tgaaaaacaa ttttttaagt tacgcacgaa tttttatttt tctatcgatg
    24901 atctcaaaga ggaacagcct tttttcgcgc aaccaaaaga cttattctct tttatgatcg
    24961 gatacgacgc cagtttgaaa gaaagtatcg aacaaatcaa aacagctctt tactatccag
    25021 atggcggatt accacttttg attacaggcg aaagtggcac aggtaaaagt tatttagtta
    25081 atttggtcta tcagtattgt ctgcttcatg atctgctaga agattctgca ccattcatca
    25141 cttttaattg tgcacaatat gcagataatc ctgaactttt gactagcaat ttgtttggac
    25201 atgttaaggg agcgtacact ggtgcagaag aaaataaaaa aggggctttt gaagcagcag
    25261 atggtgggat cttgttttta gacgaggtac atcgcttaac accagaaggt caggaaaaac
    25321 tgttcaccta tcttgatcaa ggtgtgattt atcgtatggg agaacctaat ttgtcacgcc
    25381 ggatcaaaac acgtctcttt tttgctacga ctgaagagat tactagtcat ttcttaacaa
    25441 ctttcattcg aagaatacct atccgaatcg aactacctgc acttaatcag cgtagtcgta
    25501 atgaacggct agaactgatt tactcttttt ttctcgaaga acaaagaaaa atggggagcc
    25561 ctttgtcagt cagtggacca gctttgtcac ttttaacaag tcagaaatta tccggaaaca
    25621 taggagagct gaaaaatatc gtcaaagttt cagcagcaaa agcatatgct gaacagcgtg
    25681 aacagcctga aatccatgtc acgatccatc atttgcaaaa agaactactt gcgcagccta
    25741 ttactaaaaa tacagcacag caaggaatct atattacgca agaccagacc ttagagcaat
    25801 taatggagaa gcaacagccc gaacagcagc gaatcgttaa aagttttgag caaatcctaa
    25861 ttgatttcaa gaaaaataac tgtctgctat attcttgcga aggaaaatta aagcaagaag
    25921 tgattcaatt atttgatttt ttgctgtttg agaccagtag acaagaaaaa cacgagctgc
    25981 tggtttattg gacacaatct atccgagaga cctttcgaca aatggaaact gcctatcaaa
    26041 tcaaattcga tggaaacagt gtctatgcct tgagttacta tctctatcag cgaagcacta
    26101 tcaaatggtt accggaagaa catgatatta tccaactaat caaagaatta gaacaacaag
    26161 tttctcagtc ttatccatct agttatcact atgtccaacg aattctggaa ttaagtaaga
    26221 tcaaattaga tattgaagac acaagtatgg atcggatttt actgacgatc tatctaaaaa
    26281 aagcgaaatg gtcaaaagaa aaacgactgc caaaagcgat gattgctgct cacggttatg
    26341 caactgctag cagtatggca aatgtagtaa atcgtttatt acaagaggat ctatttgaat
    26401 catttgatat gccactagat gtcacaccac agcagattgc ttcagaaatc cttgattatt
    26461 gcgaaaacag cgatgtttca aatggattga tcatattagt agacatggga tctctgaaag
    26521 aaatccatca gttttttaaa aaacagttat ccgtaccgct tttgattttg aataatgtga
    26581 cgacaccttt agcaatcaca gtaggggaat gcctgcaaaa aaatgtatca ttagaagaga
    26641 tagcagaaga gactgttcga cagatccagc cagaatggcg actgctctat ccagaggaaa
    26701 acaaacccaa agcactcatt actacttgct tcactggaat cggtacggcg gtccacttaa
    26761 gtgaactgct agaaaaaagc ttacctacgg cttgtcagtt gaaaatcatc ccatatgaat
    26821 atcagcaatt aaaagataag aaaaacagtg acccattatt ttccatatac gaagtcgtag
    26881 gaatgattgg caccacagat cctgatatca ccaatatcga ctatctttca ttagaagacc
    26941 tcatctcggg ggaaaagatg tctgtactag ctgaatggtt ggacactact atgaatgctt
    27001 cagagaagga aatattcaat cagcgcatca ttcgtaattt ttcattggaa aaagtactgg
    27061 attccgtgac tattctagat acagagaagg tgatgggaga aatcgatcat tttatgagag
    27121 aattagaggt gcagttgaat cgaagcatca gcaatcccaa aaaattagcg ttgtatgtcc
    27181 atgtgagctg tctcattgaa cgattgatcc gacaaatgcc aatcgaaacc tatcaaggat
    27241 tagagaaatg gaagcagtgt caaaaagaag ggttatctgc tattaaatct gcgtttagtg
    27301 tcattgaaga gcattatagt gtcatgatcc ccaattctga gattgcctat atctatgata
    27361 ttttgagtga agatacagag tttctctcga tagaagaaga attttgaaca taagcaagtt
    27421 gttgccacta attttggcat gcaacttgct tttttagtat gtgtaagtga aaagaggaga
    27481 tgaaaaagtg gatagagaaa ttatcttagc ttcccatgga aaatttgctt cagggatatt
    27541 agattcatta gagctgatct atgggaaaaa tcattctatt actgtattcg attgctatac
    27601 tgatgagaat tttgatttag cggaaacagt aaggcagctt tttatgaggt acaaagataa
    27661 agaaatcatt gttctgacgg atctttttgg cggaagtgtc aacaacgaat tcttacaata
    27721 tatcaatcgg gatcatgtct atctcgttgc cggattgaat ttgccactat tgattgagct
    27781 agtatctcgg ttggacgctg aagtagagac aactgttttg atccagcagg tgctaactga
    27841 ttcaaaaaaa atgatccagt tttgtaacga gcggctcaat cagaaaatag aagaagacga
    27901 attttaggag gaagaaaaat gattgtattg acaagagtcg accatcggtt attacacgga
    27961 caagtagctt tttcatggac acaaacaata ggcgcagact gtattttgat tgctaatgat
    28021 gatgtaccta cgaatgagat acgaaagaca acgatcaaat tagccaagcc acaaggagtc
    28081 aaactagtga tcaaatcaat tgatgactcg attgccgcgt tgaaaagcgg ggtgacagat
    28141 aaatataagt tattcatcgt agtggaatcg atcgaggatg catataagct ggcagaagcg
    28201 tatccagaaa tcaaaaccat caacttagga gggatcaagg caaaacctgg tactcgcagc
    28261 atcggaaaag cggtaaatat tttaccagaa gaggaggaac gcttgaaacg attaattgac
    28321 aaacaaatag aagtagaaat ccgtcaagta ccagcagata aaaaagtgga tgtaagagaa
    28381 gttttgtaag aaaggaagaa cctcaatgat tgtacaagca gtcttattag gaattgttgc
    28441 atttgtcgca caatcagaat atgcactagg gacatcgttg ctttctcgtc cgattgtgac
    28501 ggggctgttt acaggaatcg tgttaggtga tgtaaaaact gggatcatta tgggcgcaac
    28561 tttagagtta gcatttatcg gatcgttctc agtaggtgct tcgattccac ctgatgttgt
    28621 gaccggtggg attttaggga cggcttttgc tattacagct ggagccggta cagaaaccgc
    28681 gcttttacta ggtttgccga ttgctacgtt gacattgata ttgaaaaata tttacttagg
    28741 gcttttgatt ccaattatga accataaagc agacaattat gcagaagaag gaaattataa
    28801 aggagtcgag catatgcact tgcttgccgg tatcggtctt tccttgatgc ttggtgttgt
    28861 ggtaatggtt tcttatatgg tgggaagcaa tacgatcgga aatctattaa atatgattcc
    28921 tgacttcgtt caaaaggggt tgtcagtagc tacagggttg attccagctc ttggttttgc
    28981 gatgcttgct cgtttgctga tcaacaaaca agttgcacca tattttttct taggttttgc
    29041 tatagcttct tacttagaga ttcctgtgac cggagtagct atttttggtg cgattttagc
    29101 agttgtggta gtcaatatta tgaatgtccg tcaactacca cttcaaacaa ctgcagggga
    29161 ggtagaagaa gatgaagaat tctgagatca aaaacagcaa aataacgaaa aaagagctaa
    29221 atcacgtatt ttggcgttct tttcaaatgg agttttcttg gaattatgaa cgtcagatga
    29281 atatggctta tgtttatgca atgattccga ttttgaaaaa gttatatcag tcgaaagaag
    29341 aaatggcagc agctttgaaa cggcatctag agttttttaa cacgacccca catatcgtta
    29401 cactgatttt aggaatcacg gctgcaatgg aggaagaaaa taaggatgat cctgaatttg
    29461 atgtgactgc gatcgatagt atcaaaacat ctttgatggg acctcttgca gggttaggag
    29521 attctttctt ttggggaact ttgcgattga ttgccacagg tgtgggtacc tctttagcca
    29581 tgcaaggaaa tattttaggc cctatcttgt tcattttgat tttcaatatt ccgcacattc
    29641 tgtttcgcta tctagcaaca ggttggggat atcgcttagg aacgggtttt ttgaaaaaga
    29701 tccaggcaaa cggtatgatg gaaagtttga cattaggcgc gtctattatt ggactgatgg
    29761 tcgttggagc aatgactgcc acgatgatca ccatcaatat tcctttaaaa atcggttcag
    29821 gagaaaatgc tgtgactgtt caaagtattt ttgatgatat cgttccaaat atcttatgtc
    29881 ttggagcatt tggcatagtg ttttatctat tgaagaaaga agtgaaacca ttaacgatct
    29941 tgatcggact agctttcttt ggaatttttg gttcgtggat agggattttt taaaaaagga
    30001 gcagagaaaa tgtttacgat gcaagattat atctatgaag aaaaggaagt actaagtacg
    30061 atcttgaaaa agaatgattt ttcgacaaga gaacatatga aaaaaacagt gaatttactg
    30121 atcttagcaa cgggttcatc ttataacgct tgtttagcag cgaagccagc attggaatct
    30181 tatggtgatc ttactgtcga tattcaagaa cctttttatt ttttcaatta tggaaaactt
    30241 tctccttcaa tcgatactgt gattgctgtg tcacaaagcg ggaaaagtgc ttctactgtt
    30301 gaagcagtaa aaatgataca aaaacaaggg ttacctgttg ttgctatcac aaatgacgtg
    30361 caaagtccac ttgctttaga agctgcacaa attattgatt taggtgccgg ggtagaatca
    30421 gtaggcttcg ttacaaaagg ctattctgcg actgttttac agttactact cttagggata
    30481 ggaattggaa taagtaaaaa taaaatcagc aaaaaaatag aacaagacta catgcaacag
    30541 ttgcgcaaaa taatcaacca tttaccagcg attattcaaa aaacggaaga attttttgat
    30601 ggatatcaaa gtttatttcg tttagcacag cgtttcgtca ccattggata tggtccaaac
    30661 tggggaacag ctaaagaagc agagacgaaa ttgactgaaa caatccgcgt tccgtcacaa
    30721 ggatttgagt tagaagctta tatgcacggc ccatacctgg aggcagatgc ttcgcatttg
    30781 ctattcttta ttgaagggga aagtgtaaat aaggaacgtt cgcaaaagtt gcaaagatat
    30841 atgagtcggt acgttggaga gactctcacc attaccacaa aaaaagcaag aaacgagaaa
    30901 acacttggat tagcaataga atgtgatgaa tatctgtctg tattagcgct tgtcgttccg
    30961 tttcaactat tcgcttataa aaccgcagta gctaaaggta ttgacttgaa caaaaagatt
    31021 tttgaagact ttgatacagt cttgaaaagt aaattataag aggtggaaat catgctgaaa
    31081 ttcaatgaag aagaacaaat caaagcaata aaaggcgcac tagctttacg tccgcaagta
    31141 gaagaaatca tcgataaact ttatgcggaa aaatttgacg ctgtctatta tctaggaatc
    31201 ggtggaacgt atgcttcctc gatgcaagct gtcacttata tgaatgggaa aagcaacttg
    31261 cctgtctttg tacagcatgc tgcagaatat tacactactg gaaacaaaag attaacaaaa
    31321 gattctatcg ttattttgtc ctctgttacc ggtacaactc aagaagtagt gaaagcagta
    31381 gaacaaatca agaaagtagg agcgacactg attggattta tcgataaagc gaacagtaag
    31441 ttgtctcagc tatgcgattt tgtggtcact tatccagctc ctggaacaga acaaatcaaa
    31501 ttttttatgg cagcagatcg attgatgtat ttgaatggag aattcgaagc ttattcagaa
    31561 tactatgaac agctcgaacg ttatttacca acagggttag tggaagcaga gaaaaaagca
    31621 gatgcatttg gcttatcatt tgcagaaaaa catcgacgtg atagtatgca ttattttatt
    31681 ggagcaggga atcaatgggg agctgtttat tcatatgcca tgtgttactg ggaagaacaa
    31741 agctggcttc catcgaaatc tatccatgct gccgagtttc ttcacgggac gttagagatc
    31801 gtagaagaaa caaccccagt cacattattt ttaggcgaag atgaacagag agtgttatct
    31861 gaacgtgtgg ctaaactttt gccaaaaatt tgcagcaatt atacattgat agacacaaaa
    31921 gactatccag tagaaggtat cagtgaaaaa tatcgcggac gtgttttgtc tttcttattg
    31981 atgcatgtag tgacacaacg catcgatgct catgtggagc agttgaactg ccatccatta
    32041 gagatacgcc gctactatcg tcagtttgat tattaggata gactggataa aaagaatata
    32101 aaaaataaag agagcagcga taactgctcc ctttattttt ttaaaatatt ggcatcaatt
    32161 acgttataaa acacattttt tgcattatct acagttcaac ttataatctg tttaatggga
    32221 catgtgggtg ccaaccattt tttgttatgc aatagtacta tttagttgtt gcatggatcc
    32281 gtagtaaaag tccaagtaca acgagttgcg ccagtttaca tagcgttttg tatccagaat
    32341 gttgactaaa acaaaagttc ctatgtcaac cgtcaacaga gacaatctgt ccgttgcagg
    32401 acctgacaga tttagaaatg ttcaatctgt ctcttatgta ttttaaatca atactcacta
    32461 ggagaagttt cctaacctcc taatagtaat gctggtagta acattgtcaa aactgcttcc
    32521 tcttaggaac aagcaaagca taacgagtgt aaaaataaaa tgtagactat tgtaacatat
    32581 cattgattat ttcaagtaaa aacgataaaa gaagtaaaca aacacttaaa aacaatggaa
    32641 attagtccca actttaagaa atgtatacta taatggaaat tatcaattat ttatttggag
    32701 gaatatccat gaaacaaaaa atcgcagttc ttggtcctgg atcttggggc actgctttag
    32761 cacaaacatt ggcagaaaac gggcatgatg tccgtatttg gggaaatgta cctgaacaga
    32821 ttgatgaaat caataagtat catacaaatc agcatttttt acctgatttg acgatcccag
    32881 aatcgattat cggatataaa gaattggcag aagcagtgga taacgcagat gctattttat
    32941 ttgttgttcc aacaaaagcg attcgttcag tcgcacagga acttattggt aaaatgaata
    33001 ctaagccaat cattatacat gcaagtaaag gactagaaca agatacgcat aaacgaatct
    33061 cagaagtttt ggctgaagaa attccagaag aaaaaagaca ggcaattgtt gtattatctg
    33121 gtcctagcca tgctgaggaa gtggcagtac atgatatcac aacaattaca gctgcaagta
    33181 ttgatcaaaa agcagcagcc tatgtacaaa aactgttcat gaatgattat ttcaggattt
    33241 atacaaataa tgatgtgatt ggcgtagaaa ctggtgcagc actgaaaaat atcattgcaa
    33301 ttggtgccgg cgctatccat ggattaggat tcggagatga tgcaaaagca gcaatcatga
    33361 ctcgaggatt ggcagaaatc agccgtcttg gtgtcgcgat gggtgccaat cctctgacat
    33421 ttatcggttt gagtggtgtg ggggacttga tcgttacttg tacaagtgtt cattctcgca
    33481 attggcgtgc cggtaacttg ttaggacagg gacataagct ggaagaagtt ctagaaaaca
    33541 tgggaatggt cgttgagggt gtggcaacga caaaagcagc agtagagcta gctcaacagc
    33601 taggtgttga gatgccaatt actcaaacaa tctataatgt tttgtataat ggagaagata
    33661 tcaaaaaagc agcaaaagaa atcatgttac gtgacggaaa aatggagaat gaattttctc
    33721 ttcgttaaat agatgatcaa tagttaatcg tc
//
LOCUS       DAFTHM010000021        32267 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFTHM010000021 DAFTHM010000000
VERSION     DAFTHM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.021"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(29..727)
                     /locus_tag="L7C88_001000"
     CDS             complement(29..727)
                     /locus_tag="L7C88_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBP9557847.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(720..2072)
                     /locus_tag="L7C88_001001"
     CDS             complement(720..2072)
                     /locus_tag="L7C88_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBP9557848.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2295..3695)
                     /locus_tag="L7C88_001002"
     CDS             complement(2295..3695)
                     /locus_tag="L7C88_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBP9557849.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3856..4593
                     /locus_tag="L7C88_001003"
     CDS             3856..4593
                     /locus_tag="L7C88_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBP9557850.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4718..5197
                     /locus_tag="L7C88_001004"
     CDS             4718..5197
                     /locus_tag="L7C88_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBP9557851.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5194..5961
                     /locus_tag="L7C88_001005"
     CDS             5194..5961
                     /locus_tag="L7C88_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557852.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6191..6760
                     /gene="lepB"
                     /locus_tag="L7C88_001006"
     CDS             6191..6760
                     /gene="lepB"
                     /locus_tag="L7C88_001006"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBP9557853.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6864..7466)
                     /locus_tag="L7C88_001007"
     CDS             complement(6864..7466)
                     /locus_tag="L7C88_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBP9557854.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7572..8041
                     /locus_tag="L7C88_001008"
                     /pseudo
     CDS             7572..8041
                     /locus_tag="L7C88_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8147..8731
                     /locus_tag="L7C88_001009"
     CDS             8147..8731
                     /locus_tag="L7C88_001009"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBP9557855.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8734..9807
                     /gene="prfA"
                     /locus_tag="L7C88_001010"
     CDS             8734..9807
                     /gene="prfA"
                     /locus_tag="L7C88_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBP9557856.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9800..10639
                     /gene="prmC"
                     /locus_tag="L7C88_001011"
     CDS             9800..10639
                     /gene="prmC"
                     /locus_tag="L7C88_001011"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBP9557857.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10632..10811
                     /locus_tag="L7C88_001012"
     CDS             10632..10811
                     /locus_tag="L7C88_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557858.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10833..11858
                     /locus_tag="L7C88_001013"
     CDS             10833..11858
                     /locus_tag="L7C88_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBP9557859.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12033..13277
                     /locus_tag="L7C88_001014"
     CDS             12033..13277
                     /locus_tag="L7C88_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBP9557860.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13430..14377
                     /locus_tag="L7C88_001015"
     CDS             13430..14377
                     /locus_tag="L7C88_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBP9557861.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14511..15140
                     /gene="upp"
                     /locus_tag="L7C88_001016"
     CDS             14511..15140
                     /gene="upp"
                     /locus_tag="L7C88_001016"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBP9557862.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15279..15521)
                     /locus_tag="L7C88_001017"
     CDS             complement(15279..15521)
                     /locus_tag="L7C88_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557863.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15642..15714
                     /locus_tag="L7C88_001018"
     tRNA            15642..15714
                     /locus_tag="L7C88_001018"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15675..15677,aa:Thr,seq:cgt)
     gene            complement(15833..16471)
                     /locus_tag="L7C88_001019"
     CDS             complement(15833..16471)
                     /locus_tag="L7C88_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBP9557864.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16594..17226)
                     /locus_tag="L7C88_001020"
     CDS             complement(16594..17226)
                     /locus_tag="L7C88_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBP9557865.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17577..17876
                     /locus_tag="L7C88_001021"
     CDS             17577..17876
                     /locus_tag="L7C88_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBP9557866.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18371..20536
                     /gene="acm"
                     /locus_tag="L7C88_001022"
     CDS             18371..20536
                     /gene="acm"
                     /locus_tag="L7C88_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBP9557867.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(20808..21293)
                     /locus_tag="L7C88_001023"
     CDS             complement(20808..21293)
                     /locus_tag="L7C88_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBP9557868.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    21383..21728
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            21773..22414
                     /locus_tag="L7C88_001024"
     CDS             21773..22414
                     /locus_tag="L7C88_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBP9557869.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            22433..23068
                     /locus_tag="L7C88_001025"
     CDS             22433..23068
                     /locus_tag="L7C88_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBP9557870.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            23086..23901
                     /locus_tag="L7C88_001026"
     CDS             23086..23901
                     /locus_tag="L7C88_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBP9557871.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            24220..25656
                     /locus_tag="L7C88_001027"
     CDS             24220..25656
                     /locus_tag="L7C88_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBP9557872.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            25845..28292
                     /locus_tag="L7C88_001028"
     CDS             25845..28292
                     /locus_tag="L7C88_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBP9557873.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            28522..29589
                     /gene="rlmN"
                     /locus_tag="L7C88_001029"
     CDS             28522..29589
                     /gene="rlmN"
                     /locus_tag="L7C88_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBP9557874.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(29782..30885)
                     /locus_tag="L7C88_001030"
     CDS             complement(29782..30885)
                     /locus_tag="L7C88_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBP9557875.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            31438..31986
                     /gene="aac(6')"
                     /locus_tag="L7C88_001031"
     CDS             31438..31986
                     /gene="aac(6')"
                     /locus_tag="L7C88_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBP9557876.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT        11072 a         5491 c         6557 g         9147 t
ORIGIN      
        1 ttttgtcaca ttcccctttt tcgaataact aggctgtttg tccttcaaga tagggcagat
       61 ccaattcttt accgtaacgt tgttctaaag ctaggcggat caaacgagct gccaggttct
      121 catttcttgc aaggataggt ccatggaaat aagaaccgaa gacatttcgg taaatgacac
      181 cttcagattg gtcttcacca ttatttcctt gaccttgtac cactttcccc aaaggtcgtt
      241 caccttcacc taagaaagtc cgaccattgt ggttttcaaa tccataataa gtttcattga
      301 attcttcgtt atggataacg atatcaccga taaaccggtt attttcctga cttaacgtgt
      361 agtgatccag tgcactgatt ccttggatct tttctccatt agctcccatg tagtagtgac
      421 ctagcaattg gtagccacca caaatggcta acatgacgcc atcattttcg atatagttga
      481 tcaaagaatc tttctttttc tggatgtctt ttgaaatgat taattgctca aagtcttgac
      541 caccgccaaa gaaaaccaag tcatatttat cagcatcaaa aggttcatgt atactaacga
      601 tctccgtatg gcaagaaacc cccatttttt ctgctatata tttcaacatc aaaaggtttc
      661 cgttatcacc atatgtgttc atcaaatttc cataaaggtg ggcgatattg agttcataat
      721 tagccacggt tcattcctcc tttgataaat ccttgagcag ctagttcttt acgaagctgc
      781 aatacagcag tgtaagtagc taaaatatag acatgctcag ttggcaattc tttgattttt
      841 tcgattactt ctggtaattc ttttgtttct gtcaatttat tttctggaat cccggcaact
      901 tttagacgta aagtcatatc tgtatgacgg tctcctccag aaataacagc tgggatatcc
      961 atatcggcaa agttttcaaa attaccatcc caaatccagc tgacatcgat tccgtctgcg
     1021 taattggcat ttaataaagc cactaaagaa aatggataag gagctagacc aatcatatcg
     1081 attacttgat tgatacctac aggatttttg acaagtacta atgtacattt tttcccattg
     1141 atattgatga cttcttgtcg gccgaatact ttctcgtcat atcctaaacc ttgtttgatt
     1201 ttatcaggat cgacattgaa gtactctgcc actgcagtag ctgctaaagc attgtagaca
     1261 ttatacatac cgccaacttc gattccgtat tcatgaccat cgatcacgaa atctgctgac
     1321 acattgtcca tccgtaccat atcagttaat cgataatcca attcaggacg tttgaagtca
     1381 caatttggac agtaatattt ccctaagttt gcataagtga tcattttata atgcaagatg
     1441 tgatgacaat ttggacataa gacaccgtct gtattgtaat gagccatttg ttcacgatct
     1501 tcttcatggt caaagccata atattttcta ggattgactg tttcgataga attgaagatt
     1561 ggtgaatcac cgttactgat aatcgttgca tttggtgact ttgcggcacc gtctacaatc
     1621 attttatagg tcgtatagat ttctccatac cgatccattt gatcacggaa aatatttgta
     1681 aataagaaca gttctggttt catatattct gtgactttgc tcaaacttgc ttcatctatt
     1741 tctaggacag caaacttttt ctgtcctttt tttggttttg cctgcaagaa agtcgataca
     1801 attccctgta ccatattcgc accagtaggg ttggttagaa cttcatcgaa ttgctggcgc
     1861 aaaatattga ctgttaaagc ggtagtcaat gttttaccgt ttgttccggt gacaacgacg
     1921 acttggtagt cttttgccaa actatctagt atatgtggat cgactttcag cgctagttta
     1981 cctggtaaac ttgatccgcc tttaaaaaaa gtttttaatg cccattgcga cgtttttcca
     2041 actgcaatcg caaaatgact gcgtattccc attatgtaac ctccaaaaac gatttgctga
     2101 cgaataaatt caactaatca taccatatgt tgaaaaaaag gttaaattgc ttttcttatt
     2161 cttaagaaaa ggttacggct gaaagtgcat gaaatcggac aaaatcgcat gatttaacaa
     2221 aaaaacagct tgaaacaaaa tgattgtttc aagctgctgt gattttatta ttccctctta
     2281 cctatattcc cattttaacc gataataatt ttctcgcttg gatattcata gcctagatct
     2341 cgtgtttctt ttggcacgaa taacatcaat gtatatagca ttccgatccg cccaataaac
     2401 atcagtgtag caatcgtgat tttgcccaca acagacaagt ctccggtaat ccctaaagat
     2461 aaaccagttg ttccaaacgc agaagttact tcgatgatga tcgagatcag cgtttgttct
     2521 tctgtagcag ataaaaaaac gatacaaaag aaacacatac caagagaaag cataaagaca
     2581 acgactgatt ttcgcacatc atcttgatcg attctccgtc caaaaatatt gatgttatct
     2641 tcacttttga ggaaggaata tagatacaaa ccgatgattg ctacagtagt tgttcgaatc
     2701 ccgccgccta cagaactagg actgcatccg ataaacatca gtaaagaaaa aatgatcagt
     2761 gttgtgattt gaaaatcacc caaatcgtga atctgcagac cagcattacg agtcgtaatc
     2821 gaataaaaca tcgaattgat ccatttgaca ctcatattgg aatcttggaa taaatggtcc
     2881 ttttccaata gataaatcaa gacagttccc gaaacaaaca agataacaaa agctaacaca
     2941 gctaatttgg taaacaagga aaaacgaaac ggaagcttcg cattggaacg tttgtataat
     3001 agccattccc ggcactccat caatacagga aaaccaattc ctccgacaaa aatcaaaaac
     3061 atgatcagga tcaagaaaaa atagtcatgt gcaaagggct tgatggaatc cccagtgacg
     3121 tcaaacccag agttcgtgac agccgatatc gcctgataaa aaccgtaaaa aacggcatca
     3181 cgccaacgat caaaatagcc tctgtaataa aaataaatag aaaagaatgt cccaaaaagt
     3241 aattgaaacc agattaaaat agcaaaagtg atccgaatca gtcggacgat accagacaaa
     3301 cgcggttgat tcatatccgt catgatcagc tgtcgctgtt tcagtgtgat ccgtcgttta
     3361 gaaaaaatga caaaagcagt agaaatcatc atgatcccca aaccaccaac ttgaaataat
     3421 atttccagca gtataatacc gttatcattg aacacagaat tgatatcaaa agtcgatagt
     3481 ccagtcacac tcactgtact gattgccatg aacagcatgt ccacaaaaga aacatggcta
     3541 tctggttcgc gaaaaatcgg catataaaat agaacgagtg ataagaccgt catcaatata
     3601 taataaaaaa cgatgatttg gatcgatgag aaatgattgg cagcaaactt ctgtcctcgc
     3661 cgctgcagcc ttcgaaagaa taaatcaaca tgcacagtac tatcctcctg acaatagtcg
     3721 tttctaccag tatacaaggg gaattaggaa tactcaaaga aattatcaaa cagataacaa
     3781 tacagctttc gattaaaata gaaatggctt ataataagga aaatcctaga aaaaagaagg
     3841 aggaggaata acaaattgat taatgctcaa caaatcgtag aaaaaatgaa aaatcaaaaa
     3901 ataaattatg atacagttct gaaaaaaatg atcatgcaat gggagaaaga agaagtaaag
     3961 cctaagatat taatacatac atgctgtgct ccttgcagta cgcacacatt ggaattcatg
     4021 tctcaatatg cagagatcac gttatttttt tcaaattcga atattcatcc taaaagtgag
     4081 tatttgcgaa gattacatga acaaaaacga tttgtagacc aatttaatga gaaaactgac
     4141 catcatgttg cgctaatcgt tgatgaatac cgtccaaatg aattcaccaa aatggtttta
     4201 acaaaccatc ttgaaaacga aaaagaaggt ggtgctcgct gcagtgcatg cttcaatatg
     4261 cgattagatc ttgttgcgca aaaagcgcaa gaactaggat acgattactt tggaagtgcc
     4321 ctgaccatct cgccaaagaa aaatgcagct ttgatcaatc agatcggaat ggatatccaa
     4381 aagatttacg ggacacaata cttgccaagt gatttcaaga aaaacaaagg ctatgaacgc
     4441 tctttgcaaa tgtgcaaaga gtatgatatt tatcgccaat gttattgtgg ttgcgtgttc
     4501 gctgccaagc agcaaggatg cgatctgaaa gaaatcaatc gggaagcaaa agcttactta
     4561 aaaacatcaa ccgtagtttt tgaggaaaat taaagaaatc tttcggaaaa acgtaagaaa
     4621 aaaataaaga atttatggta gaaataaggt agactgtata atttgtccgt agtaaagtaa
     4681 ggaaacaaga ataaatttca atgaaggaag agataagatg cgaaaagtag cacctatttt
     4741 gaagccaatc gctgtattaa caatctcgac gattgtcgcg actactacag gtattgtgaa
     4801 tagttccagc taccgtgcac caagttcaag ttctagtact gtagaagaaa caacaccaac
     4861 tacttcagtc tcgacatctg aaccaacaac aacggaaagt ttgaatgaaa ccactacgac
     4921 aagtacatgg gacgatacaa caactagttc gtcgtatgat gagacatata caactgacag
     4981 ctcaagcgaa acaagtaata cggtaccaga tggcactcca tcggattcaa ccaatccaag
     5041 tacaagtccg gatacaagtg ctagctccga aacgatacca agcagtacga ctgtagatga
     5101 taacacgcaa aatgatgatg cagcacgtac agcacagcaa aaccaagatt caggaaatac
     5161 ccaaacgtat aaccagcaag caggtgattc tcaatgacat ttttactaga ccttatcaac
     5221 ggggtgcata aattccttgg ctatttagac atcagtccta aatatcttaa ccgtggatat
     5281 acgattttaa gtgtgattcc cacgctttat ttattgagaa ttgtttatgg actttggcaa
     5341 aaccaaaact atcttcaatt tttcttatat ggacttgcat ttctagtgct tgtttatttt
     5401 actgttttaa atgtatttta ttacttttta gataaaaaca cgaaagccga tgtcactcag
     5461 ctttttgtga agtatttacc tgatgaagcg ttcaacatcc agacagaaga atcgatagat
     5521 aatggaaatt cgatcgataa agtgaataca caagaggtca tggtttctta tgacgaagat
     5581 tatcaattga aattagccga gaatatgcgg tatttgattg gaaatggtga gatcaaaaca
     5641 aatgaactcg gtcgcatgga tggatttctg gtcgatagaa atacattgta tccttattac
     5701 tatgtcaaga aaacaggaga gaaagagtat gttctaaata ttggacgaag ctactcggac
     5761 atggaaaaag tagggaccat tcgacttgac tcaacagaag acacattgga acctgtcgga
     5821 ttgttcatcg tcggcggtga ttttgtcaaa gacgggttac gctatcatga gccttatcgt
     5881 ctgaaattga ttgcaaaaaa ggcacagtcg caggaagaac cagtggttta tagtcgtagc
     5941 caaagaagaa gacattcata atgtgatgaa acgccgtgta tcagtggttg cgataaaaac
     6001 gtttattcgg aataaggggg atgtgacacg tcttttgtca cgttcctttt ttatataacg
     6061 agaaagataa gacgaacaca tcacttattc tttcctttca tttataaaca ttgtagaata
     6121 aagaaagtac aacgaagtat tgtgaaaaaa cgtaataaat aacgaggaaa atacaagtag
     6181 gaggtaagct gtgaaagaat ttttgaaaaa ttgggggatt ttgatccttg tattagcggc
     6241 tattttatta gctagagtgt acgtgtttac accagttact gtaaacgggc attcgatgga
     6301 ccctacatta agtgatggac aacgattgat ttcatctaag atctcaaact atgaacgaat
     6361 ggatattatt actacaaagg aaccggggga tgaagaacgg atgattgtta aacggatcat
     6421 cggtatgcct ggagatacag tcaagatgga aaatgaccag ttgaccatta atggcaaaaa
     6481 gtatgatgaa ccttatctgg atgagttcaa aaaagaattt tcagaagata agttacaagg
     6541 agaatatgct tatagctcag gattccaagc acaagcagaa agttcatcca cctttacgag
     6601 tgactttgaa tatactgtgc caaaaggaaa gtatcttgtt ctaggcgata accgcttgat
     6661 ttcaaaagac agccgaatgt ttgggttagt cgacaaagat atgatccaag gaaaagttgt
     6721 tttccgttat tggcctcttt cagaaattaa aatcatgtga tgaaaaaata aaaagaagct
     6781 gtgacatgtt ttttgtcaca gcttcttttt ccgaaaattc cttcttattt cttggagttg
     6841 ctcacttttt ttgcaatctc attttaagct ttttggctga tggataagaa aagcgaagcg
     6901 tttttgttca taaatagctt ttccccacga tggaaggtat gactagtagc agagacaaag
     6961 cccgtttttt ccaatcgatt attcaattct tcttggctaa agccattatg gactttcgga
     7021 tgactaattt gttcattctt gtcaaagtct acgatgatca attgaccgcc aggagctaaa
     7081 atttcataaa gttttgtaag aatattctcc gtatcaggaa tgtgtaaaag tacaagtgat
     7141 agaaggatga gattagcttg gacagcagga aattcgacag aagcatcagc gtggatcgtt
     7201 cggacatttt tcagatctgc tgcttggatc ttttcttctg ccattttcag catagtttct
     7261 gaagcatcgg caatgatcag ttctttgaat ctttccgcaa gcggtaaact aacaagccca
     7321 gttccgcctc cgtaatccag caggactttt tggtggctgt cgcgcggtag ataagtagtt
     7381 agttcttcgc gaataatctt ggctaatgct tgacggtcag gggaatcata atggttagcg
     7441 atggaatcaa aaatattttt tgtcatcaaa tagctcctta cgtaaaactt tgaaatttta
     7501 acttattata gcacgtgaaa agaaagaaag catgctatac tcaattcaaa aagggagaat
     7561 ctagaaagaa tatgccgata tcgtttgtaa aagatagaga ggaaaaagga aagtgtgtcc
     7621 gagaaatatt actagacttg cctgagtggt ttgggcttcc tgaatcaacg gaaaaatata
     7681 tcgaggaatc aagtaaacta cctttatggt gtgaaaaaag aaaagaagaa tatttaggct
     7741 ttatcactct ttcacagaca agtgaagata ctgccgaaat ctattctatt gtatgggaat
     7801 aaaaaaagac tatcatcacc aaggattagg aacaaaactt tttaaagaag cagaaggtta
     7861 cgcagcaaaa cattacaaat atttgcaagt gaagactgta gacgaggggc actactctat
     7921 atatgatcaa actatttgtt tctacgaatc attaggattt tcaaggttgg aagtttttcc
     7981 aaatttatgg gatgaatgga acccatgttt agttcttgtc aaaaaattgg aacaaaagtg
     8041 agcaatagat ttaatactaa tctgtgcttg atgaaaattc tcactgtaaa aaatgctgaa
     8101 aatcaagtat aataccatag gaacaaactg gaaggtgaaa aagagcatgg cacaactatt
     8161 ttttaagtat ggcgcaatga atagcggcaa gacgatcgag atcctaaaag tcgcacataa
     8221 ttatgaagaa caaaataagc cagttgtctt aatgacaagc ggtattgata caagagatgg
     8281 tttaggcgtt gtttcaagcc gaatcggact gaaacgtaat gcgatgccga tatttgaaga
     8341 aacagacgta tttgacgtaa ttcagaaaat ggaaagcaaa ccctattgtg tgctgatcga
     8401 tgaagcgcaa ttcttaaaaa agaaacatgt cattgctttt acgagaattg tggacgaatt
     8461 ggatattccg gttatggcat ttggtttgaa aaatgatttt cgaaacgagt tatttgaagg
     8521 atcaaaatat ttattgcttt atgcagacaa aatcgaagaa atgaaaacaa tctgttggtt
     8581 ctgccacaaa aaagcaatca tgaatttaca ttatattgat ggaaaccctg tttatgaagg
     8641 cgatcaagtg caaattggcg gaaatgaagc ttattacccc gtttgtcgaa aacattactt
     8701 tcacccatca atgattacag aaggagaata agcatgtacg atcaattaca agcaattgaa
     8761 gaccgttatg aagagcttgg agaactttta agtgacccag aagtgatttc tgatacaaag
     8821 cgttttatgc agctttcaaa agaagaagca aacacgcgcg aaacagtcga agtttatcgt
     8881 cgttataaag aagtagtaca aggaatcacc gatacagaag aactgcttgg tgaaaaactg
     8941 gatgatgaaa tggctgaact agcaaaagaa gaattatctg aattaaaaaa agaaaaagaa
     9001 gtcttagaag aaaaaatcaa gatcttgctt ttaccaaaag atccaaatga cgataaaaat
     9061 atcatcatgg aaatccgtgg agcagcaggc ggagacgaag cagcattatt cgctggcgat
     9121 cttttcaata tgtaccaaaa gtatgctgaa gcacaaggct ggaaaacaga agtgatggaa
     9181 gctaacgtta ccggaatcgg tggatataaa gaagtgatca tgatgatcac cggagacaac
     9241 gtatattcga aattaaaata tgaaagtggt gcgcaccgcg tccagcgtgt tccttcaact
     9301 gaatcgcaag ggcgtatcca tacttccacc gcaacagttg tcgtgatgcc agaagctgaa
     9361 gaagtagaga tcgatattga agacaaagat atccgtacag atatctatca tgcttcaggt
     9421 gctggcggac agcacgtcaa taaaacagca tctgctgtac gtttgactca cttaccaaca
     9481 gggatcgttg ttgctatgca agatgaacgt tctcaaatca agaaccgtga aaaagcaatg
     9541 aaaatcttgc gtgctcgtgt gtacgataag atccagcaag aagcacaaag cgagtatgat
     9601 gccaatcgaa aatcagcagt cggaactggg gatcgttcag aacggatccg gacgtataat
     9661 ttcccgcaaa atcgtgtgac tgatcatcgt atcggattaa ctatccaaaa attagatcag
     9721 attttagcag ggaaattaga tgagatcgtt gatgcattga tcatgtatga tcaaacatca
     9781 aaactggaag ctatgcaaaa tgggtaaaat gacctatcga gaagtcctgt cacgggcttc
     9841 ttctttttta gaggatcatg ggaaagaagc atatagtatc caatttttat ttttggaacg
     9901 aaaacaatgg aaaaaacttg attggctcct tcatatgaac gaagagattt cagaagaaga
     9961 acagcggttg atcgaaaccg atctgcgact tctgcttgca gatcatccac ctcagtattt
    10021 gctaggatat gcagattttt atgatcatcg gttaaaggta actgaagcaa cactgatccc
    10081 tcgaccagaa acagaggagt tagtcgaatg gtgtttagac gagacgcctg gtgtaccgtt
    10141 agaagtgata gatattggga cagggactgg agcaattgct attagtttga aagcagcaag
    10201 aaaaaattgg catatatctg ctgtggatct ttcagaagaa gcattagaag tagcgaaaga
    10261 aaatgctcag aaagaaggaa cgaaaatcag tttttatcat ggagatacat taggaccagt
    10321 aatggatcag caatttgatg tgattatttc taatccgccg tacatcagtc ggaatgaatg
    10381 ggaactgatg gatgaaagtg tccggtcatt cgaacctaaa atggcccttt ttgctgagaa
    10441 cgatggatta gctatttatg aaaaaatagc agttgaagca ccaagcgtac taaaatcaaa
    10501 tggaaagatt tttttagaaa tcggatttcg ccaaggtgaa gcagtaaaaa aaatatttca
    10561 gcaagcattt ccagataaaa aagtggcgat aaaaaaggat ctttttggca atgaacgaat
    10621 gatccaagtt tatggttgaa gttgtggatg aaaaattttt tatttgtttt tttattataa
    10681 aaaaacactt atttgacaag gatgtaaacg actttttggt ttatcaacaa gtttatccac
    10741 tattgacaaa tagattatcc acaaacagtg gaaaacttga ggataaactc agacaaaata
    10801 agaatgtatg aaaaaggggt tgtggataaa ctgtggaaac gaaacgatat gatgaaacag
    10861 aattgcaaga ggcagccgaa gcactgaaag aaggagaact tgttgctttt cctaccgaaa
    10921 cagtatacgg attgggcgcc aacgctcttt taccaaacgc tgtcaagaaa gtgttttctg
    10981 taaaagggag accgcaagat aatccattaa tcgtccatgt cgcctctttt gaacaagtaa
    11041 aagagtatgt ggacaacttt catccggcag cagagaagat tgtgaagaac ttctggcctg
    11101 gaccattaac tttgatattt aagatcaaaa aagacacttt gccctcagtt gtgacgggag
    11161 gattatccac agctgcattt cgtataccgg ataacaaaaa aacactagaa gtaatcgaac
    11221 tttccggtgt tccgcttgtc ggtccaagtg caaatacgtc gggaaaacca agtccaacga
    11281 ctgcagatca tgtatatcat gatctacaag gaaaaattac cgggattatt gatgatggag
    11341 ctacgcgaat tggtgtagaa tccactgttc ttgatttaag tgatccaaca gccatgccta
    11401 tgattttacg accaggtgca gtaacgaaag aacaaatcga agcagtcatc gaatctcctg
    11461 ttgctattga tcagcatctt gtaaaagaaa atgaaacacc aaaagcccct gggatgaaat
    11521 acaaacacta ctcacccgat acacgtgttc tgatggtcag agatggcgat tggtcaactg
    11581 cagttcaatg ggcaaaaaat aagaagatcc gtgcaggtgt catagcaagc cccgaaattg
    11641 cggatcaagt gcggacagat actgcagctg tttatatgta taacgacaac tcagtagaag
    11701 cggcggctaa aggattgttt gcaggtctaa gaggattaga tgaaccaaca cttggattag
    11761 atttgatttt tgtacaagtg tatccagaaa ctggattggg gaatgcttac atgaatcgct
    11821 tgaaaaaagc agcaggacaa aattattttg aaaaatgatc aattggttat tgtcgcattc
    11881 ttttagtatg atacaatgct atcaagtaaa tcttctatca gtgaacgaaa aactaagcgt
    11941 aactaatcgt aatagaagag atacgaatat ttggcaattt gtttttgatg ggaaaaataa
    12001 aattgtagga aaataaaaag gagctgttgt ttgtggtaga ttacaaaacg tttgaccctg
    12061 atctttgggc tgcgatcgcc aaagaagaag aaagacaaga acataatttg gagctgattg
    12121 cctctgaaaa ctttgtctcc gaagcagtga tggctgcaca aggaagtatc ttgacaaata
    12181 aatacgcaga aggttatcca gggcatcgct attatggtgg gtgtgaattt gtcgatatcg
    12241 ttgaaaattt agcgattgac cgtgcaaaag aattattcgg agcgaaattt gcgaacgtcc
    12301 agcctcactc cggctctcaa gccaacacgg ctgcttatct cgctttggta gaaccagggg
    12361 acacgatctt aggaatggat ctttccgcag gcggacatct aacacatgga tcaccagtca
    12421 acttcagtgg caaaacctat cactttgttg cttacggtgt tgatccgaca acagaagtta
    12481 ttgattataa tgtggtacgt attttagcta gaaaacatca accaaaattg atcgtagcag
    12541 gtgccagtgc ttacggacga acgatcgact ttgcgaaatt cagagaaatc gcagatgaag
    12601 taggcgcaaa actgatggta gatatggcac atatcgcagg attagtagca gcaggacttc
    12661 atcctaatcc agttccttat gcagatatca caacgactac cactcataaa acattgcgtg
    12721 gccctcgagg cggcatgatt ttgacaaacg atgaagcatt agcaaaaaaa ataaatagtg
    12781 cggtatttcc tggtattcaa ggcggccctc tagagcatgt gattgcgggt aaagcagtag
    12841 cattcaaaga agcattagat cctgcattta aagaatatag tgaacaaatc atcgccaatg
    12901 caaaagcaat ggtcaaagtt ttcaatcaag caattggaac cagagtcatt tcaggggcga
    12961 cagataatca tctgatgttg atcgatgttc gcgagttagg tataaatgga aaagaagcag
    13021 agagcatttt ggacagtgtg aatatcactg taaataaaaa ctcgattcct tttgaaacac
    13081 taagtccatt caaaacaagc ggtattcgaa tcggcacgcc agcaatcact actcgcgggt
    13141 tcaaagaaga agatgctgta aaagtggctg aactagttgt caaagcatta caagcaaaag
    13201 atgataacgc tcaactagac gaagtcaaaa caggtgtacg cgaattaact gaaaaatttc
    13261 cgttgcataa aaaataaaaa tttaaattcc attagtaaac agaaaagttc aatgttgggc
    13321 ttttctgttt attttttggg aaaacggatt ctttgacaat atcggtgatg ctctctagta
    13381 tatgaggtgt aattttagtc ttcacactaa atctcaggga ggaaaagtca tgactgatcg
    13441 tatctcgtta gaaaaggaag cagtagcatt cagtgatgca aatgcgcctc atccgcgtat
    13501 ctatgaacta gcaccggaag aaggaagagt tttactagaa gaagtacaag aatcacctgt
    13561 gaacaaatat tccgtcgata ttgaagactt gatggtggat actggcgaat ggggaaaact
    13621 caatattcgt ctcgtacgac cagaagggaa tatggataaa ttaccagtta ttttttatat
    13681 tcatggagca ggctgggttt ttggcagtgc tcaaacccat gataaattga tcagagaact
    13741 tgcggttcgt acgaattccg tcgttgtctt tccagaatat agtcgatcac cagaagcaaa
    13801 atatccaaca gcaattgaac aaaattatgc tgtgttgcaa cagctgaata aattagccaa
    13861 gtcaaaaaat ctggatctcg agaatctaat cgttgcagga gattcagtag gtggtaacat
    13921 ggctacagtc atgacgatct taacaaaaga acgaaagggc ctcccaatat ccaagcaatt
    13981 gctgtattat ccagtcacaa acgctgattt tgatacagat tcctatcatg aattcggaga
    14041 aaactatttt ttgacaagag aaggaatgat gtggttttgg gaccaatata cgacgaatga
    14101 agaagagcgt gctgaaatca cagcttcgcc tttgagagca aatataaatg aactaaatga
    14161 tcttccttca gcaatgattt taacgggaga agcggatgta ttaagagatg aaggtgaggc
    14221 ttatgcgcgc aaacttcgtg atgcaggggt tcctgttaca caagtacgct tccaaggaat
    14281 catccatgat tttgtcatgg taaatgctat ggatcagaca aaggcaacgc gtgcagcaat
    14341 ggcattatct acttcttgga tcaagaaaaa agaataagct ttgcttgtcc gcaggaaaac
    14401 ttcttttcaa aaacggattt tcttaggaaa aatggcgagt ttgactagtc aatcacttga
    14461 ttttgtttta caattaaaaa gaaacgacag aacaaaggag agcttaaaaa atgggcaaat
    14521 ttcaagtgat cgatcatcca ttgattcaac acaaactaac tattattcgg gacaaaaact
    14581 gcggaacaaa ggtttttcgt gaagtagtcg atgaaatcgc tatgttgatg gcatatgaag
    14641 tatcacggga tatgccattg gaagacatcg tgatcgaaac accgatcact gaaacaacac
    14701 aaaaaacgtt gtctggtaaa aaagtagcga ttattccaat cttgcgcgca ggtattggaa
    14761 tggttgacgg tatcttggaa ttgattccag ctgctaaagt gggacatatc ggtctttatc
    14821 gagatgaaga aacattggaa ccacatgaat atttcgtcaa acttccagaa gacattgatg
    14881 cacgtcagtt gtttgtagta gatccaatgt tggcaacagg cggatcagca atcatggcaa
    14941 tcgatgcatt gaaagaacgt ggcgcgtcga acattaaatt tgtttgtttg gtagcagcac
    15001 ctgagggagt aaaagctttg caagaagcgc atcctgatat tgacatctat acagcttctc
    15061 tagatgaaaa attgaatgaa catggttata tcgttcctgg actaggggat gcgggtgacc
    15121 gtttgtttgg tacaaaataa gtaaatacga aaaagggtgt gacacaactt ttgtcacatc
    15181 cttttttggt catttttaac gtttgatgca gaacagcttt ttcacagctt tcgtttgcat
    15241 ataaaaaaac catcccaaaa atgcagagat ggtcaaattc aaatcttttt tagttctttg
    15301 tagttaacga ttactacacc cttactttgc gtcatcaagt tcgcattttc tgcagtttca
    15361 tcaatctcaa caacagcgga atttttcaat tgctttgaaa tcgttccagt ttgcgacttg
    15421 ccgtgaattg tgaacattac gtgagtattg atcttgaatt tttcaccaat ttccgatggt
    15481 acgatagttg tatcaaattt tccaaaagtt gccattttca taaaacctgc ctttcacatc
    15541 aattatacca cgttttatga aaaatatcat gaaattaaac taattttcca tcggactctt
    15601 tacaatcagc caaatagagt atataatttc ttttggataa ggccagctta gctcagttgg
    15661 tagagcaacg cactcgtaac gcgtaggtcg taggttcgat ccctatagct ggcattaaaa
    15721 gagaagacag atatatcaag gatttttaat ccattgatac atctgtcttt ttgtttaaag
    15781 gaaataaagt atgctttctt agcaatagag catgtattat ttctataaaa atttaggaga
    15841 ataaaacgac tagcaatata gctgtgaaat caaatatcac atgaactgcc caacttgtaa
    15901 tgatcgagtt gcttttaatg gcagcttggt tgaataacaa tcttgccacc ccttgtatca
    15961 aaaggatgtg tgctacagtg tgtaaaatat ttccattatc ataagtactg taatggataa
    16021 atccaaagat gattgctgac aagaaactag cgacaggaat gctgaactta ctagaaaaaa
    16081 tagcgagaaa atacactgag aacaattctt ctccaagtat catgataggc aaaataataa
    16141 ataataacgg gctgaaagcc tcatttattg gattgcctgt taaaccccat ttcaaaattt
    16201 gttgcaaaaa taccgagact gcggcactga ttactacatt gataaaaaaa tatttggcta
    16261 tatttttgac aggagcgaca ggtttcgaga acattttttt cgtatctttt ttaccaaaaa
    16321 caagtgtaaa tgctataaat ccagtgatag ttaaagaaaa aatgctaata atggatggcg
    16381 caaatagcaa ccctaacaaa ccgagtacaa cgacaatagt gcccaatatc ccttttttaa
    16441 gttctatttt ttttcctaaa atgttattca tgataataac tcctactatt cagtttttga
    16501 agatagagtc agtatacatg aagagttaaa ataggcaatg tttttttatg gatatttgta
    16561 ttgctaaaaa tttatcttat atattcattt tgattatact acttttattt gtaaaaattt
    16621 tctagcaaaa ccaagtgctt gcaactgatt aagcgtacaa ttttttagat gttccgagcg
    16681 tacttcaatc atttcaaagg agttgctact taaatcgata ttttttaaat cagtatcaaa
    16741 aaagctagca ttttctaaat cattagtaga aaacattatt ttagtgaggg aacagtctac
    16801 aaaatctgcg cttgataaga cagagtgctc aaaggtactt tcttttatgt ttgaaccaga
    16861 taaatttaca tagtccattt tacaattctc gaataacgtg ttcccaatat aactttccat
    16921 caatttagta cctgttaatt tacaattgac aaatttcacg cgatgcaaca tgctttttgt
    16981 caatatacag cctgaaaaat cacagttttc gaatatacag tcggtaatct ccattctttg
    17041 aaaatcattg gaagcaaaaa atgcatactt gaaaatagat ttgtaaataa ttggatggca
    17101 gattatttgg ttttcgatga cctctttttg tgaaaggata ttatacagtt caaaatcttc
    17161 gttttcatag atatgaaaaa aggatccttt attcaagctt gcttcattaa ctttaggaaa
    17221 aatcatattt aattacctcc attttcataa agtcatatta acaaaagcta aaccaactta
    17281 cattagcaga aaatgagata ggttttcgcc tttttcgata acgatagtgt cgctatctct
    17341 tgaaacgttc ttagaattgc cctgagagac acaaattagg cgtaattcta ataaaaatct
    17401 tagaataaaa atttttactg atttaattta gaatgttttt aaaataaaaa tcgttgccat
    17461 aacagtgtat tgaaaggttt taacaatcca gtaatgattt aaaaaaatct agatgtagcg
    17521 tatactttgt ttatagaatg tagtgggaag aaatatattt ttgggaggaa atcgtgatgt
    17581 ctaaaagtga agaaatagaa aacatggtac taaaattata tgatctcgtt ttaaatccag
    17641 agatcaaaga aaaggaacgt atacttttga tagacgcaaa gacaggctta gaaaaaggtc
    17701 agtattatcc taaagtcata aataatttgg aacgtagttt acgtccgtta gcaatcaggg
    17761 gagaattgtc taaaccagta tcaccgtttt atatggagat atcaacaata ggaaaatttg
    17821 aaaaagaatt aggtcgagga atggcttcgg caccgattac ttttgggcat ttataaaaac
    17881 gagttattca tctcaatgaa ttaaaaagta tagtcaatct cataatgcag gctaggttca
    17941 tttatttgaa cagagtctgt atttttttat tctaaataaa gaaacagatg tttctttata
    18001 ttgtatttta tcctttaatt aacacaaaaa cagctagtat aaactaataa tgttaattaa
    18061 aagtgtattt tatgaaacta tcgttattta ttaatgttgc atttttgtaa gttaaaaatt
    18121 ggaaatatag attgaaaaaa tgaaagcaat aagtaaaata aaatgaatat atgcgaaaaa
    18181 ataatttaca ttaggaaaaa ccttgtaaaa acagtttttt ggcatattta ttttttataa
    18241 atatttgtaa aataactatc aattttttag ttaaaagatt ggaaatgagt gggggaggaa
    18301 ttgaagaaag gatttttgag agatgatata gtaggtttta tttttagtta aaatagggga
    18361 gatagaaaaa atgaaaaagt gtagaaatat tattttatca atgttattta ttattactaa
    18421 tataacatca ctgattcctg ttcatgtcta tgcggatgca ggcagagata tcagcagtaa
    18481 tgtcacttcg ttgaccgtgg acccaacgaa tattacagat ggaggaaaca taaaagtaaa
    18541 attctcgttt gacgaaaaaa aacaaaatat ccaaccaggt gattatcttt ggatcaattg
    18601 gccaagtgaa ggaaatattc gcggtgaagg attccaaaaa gaaatcccat taatgattga
    18661 aaataaaaat gttggaactt taacggtcag aaaagattct gcgcaggttg tgtttaatga
    18721 aaatattaaa aacctagact cagtagaagg ttgggggcaa tttgagatac aggccagaaa
    18781 cgtaaccgat accggtgaag aaaatacggg accattcacc gtgacgagcg gtgataaaac
    18841 agctactgta aatgtgacaa agccagcttc tggttcttct tctagcgttt tttattataa
    18901 aacaggagac atgctacctg aagatactaa gcacattcga tggtttttga atattaacaa
    18961 taacggcact tatgttgaac aaccagttaa aatcagtgat gaaatccaaa gtggacaaag
    19021 attagatcca agtacgtttg aaattaatca aatacactta ggtgaacaga aggtttatag
    19081 aggagaagag ggaatccaac aatttttaca agatttcccc agcgctacat ttaatttttc
    19141 agtaactgat aattacattg aaataactat accaaaaaac tttgtcaatc ttaggaaaat
    19201 aatggtgagt tataagacga tcatagaaaa cccagaacaa ataaattttg agaatcattc
    19261 ggaagcttgg tttaaagaat ttaataaacc tgctgttgat ggagaaagtt tcaatcatac
    19321 agttaaaaat atttcagctt ctggtggagt caacggtaca gttagaggcg aattgaagat
    19381 tttcaaatat atcaatgaca cagagattgg tatcccaaat gtgactttcg aattaagacg
    19441 agcagatgaa cagcctattc aaggacagtc tagtatcctg ttgacttcga atgaacaggg
    19501 agaagctagt atcaaaggcc tgcaagtagg agactatgtt gtaaaagaaa aagaagcacc
    19561 caattggatt gattttgatc cactaagttc aaatgaactc aaattctcca taaacgaaaa
    19621 tgatacagag ggagtcagtt tacctattta taacaagaaa aaggttacga acatcacagc
    19681 aactaaaatt tggaacggtg gaaccactcc aagaccgagt atttatttta aattattcag
    19741 agcaagtaca aacaattggg aaccagttcc tgatgcagaa acaaaacgat tagacaatgg
    19801 aataacttca gtgacttggg aagatatcca acagtatgat gatagtggaa acgaatatac
    19861 gtttaaagtg caagaagtag atcaaaacgg aaatgattat gtcccttcag gttatcaaaa
    19921 aattgaaaac gggctagtcg ttacaaatga gaataaagaa gtcatttcag tctcaggaca
    19981 aaaaacatgg gaagacaatg agaaccaaga cggcaaacga ccgacgacga tcacagtaaa
    20041 tctattagcc gacggtcaac cgatccaaca caaagaagta agtgaaaaag atgattggcg
    20101 ctatcgtttc acaaatctgc caaaatacag agacgggcaa gaaatcatct atactgtaac
    20161 ggaagacaac gtgcccgaat acagtacgac gattgacggg tataacatca aaaacagtta
    20221 tacaccggaa aaaacaaata tatctatacc aggtagccat ataacaccgt ggaaaaattt
    20281 tccagagaag acagagagag agaaaattag aaatctattc tctcaaaaat tgcaaatatt
    20341 tgctcataca ggagaatcca gcgaacaaag aagcaattat attagtaaga gagctgtacc
    20401 taaacagata acaaataaat caaaaagcat tcttcctaaa acaagtagta aaaaatctag
    20461 ttttgctgta atcattggtt tattgatagt aactatctgt gctgggatat tcttacaaaa
    20521 atataaaaaa gtttagttag aatataatat tttttgttaa atatgactga aatcaaaaga
    20581 ataaaattcc gatttataat cgaaaaaaga agcattttta tatatgcttc ttttttcgta
    20641 gaatcaataa atatggattt ggctaactat ggaagaatac tcgtattagt tttcagcgtt
    20701 catactagtt gttacattgt ttgattggcc aaaagaattt ctgatatatt ttgtgctaaa
    20761 taaagaaaaa gacgcttgaa ttgggaaata agaaaactac tctatcatta caaattttca
    20821 taaactggca gatgttctaa gtaaacaagt atcttttcaa agtcggaaaa atccataatc
    20881 aacgtagtgg tattgatatt tggatgaaag cctacggtat cttgacgatc aatagcagca
    20941 tcgatcacga cttggatttt tttctctttg tcgtgcatca atgctaatgg agtcactgta
    21001 cctgctggaa cgcctaggag gtcaggaagc tgttcttcag aaacaaaaga taagcgcttt
    21061 tcttttaatt gttcagctag ttgttttaaa tcggcgtgct tttcatcagg caagatgaca
    21121 agatagattt gttttccttt tcttgatttc aataatagat tttttacttg cggaccaggt
    21181 agggaaaaag ggacattttt gactgacgta atcgcaggat gatcgacttt ttgaaaagag
    21241 atacccagtt tttttagtag ttcataagct tcttgttcgg ttgcacgact catcgcgcat
    21301 caccctcctt tttttattag tgtatcataa aaaagagttg acaaatgaaa aataatcatg
    21361 taaattacac gtaaagttaa aacaaatgac atcgaaaaga agagtagccg ttaggtgttt
    21421 ttagagagtc tctggttggt ggaaagaggc agcagttaac cgtgaaacac atcttggagt
    21481 cgattttctg aagcgtatag taggaaaatc cggggagccc gttacagctg cggtcgttgc
    21541 tagatgacca gataaggctg gcttttccgt gaggagtcgg taaaaaaagg tggaaccacg
    21601 tgattaacgt cctttgatct tcggatcaaa ggactttttg ttttcatctg aacggcaacg
    21661 actgtgtgag gttttttctg caaggaaaaa ataaacagag gtggaaccac gtataatacg
    21721 tcctcttggc atttgccaag aggatttttt tattttaaag gaggaaaaga agatggagta
    21781 tttgattgaa gttatgccgc aattattagt aggagcactc acaacattga aattattttt
    21841 atttaccttg attggctcat taccattagg gattgtttta gcattaggat tgtctttgca
    21901 ttttaagccg ctacgctact tgcttcaaac atatgtatgg gttatgcggg gaacaccgct
    21961 gttgttgcaa ctgattttta ttttttatgg gttgccgacg attgggatcg tttttgatcg
    22021 tttcgaagca gcactcattg cctttatctt aaactatgca gcttattttg cagagatctt
    22081 tcgtggaggg atacaatcga ttcctcaagg tcaatatgaa gcagcgcaag ttttgcaatt
    22141 aagtcccttt caaacggtga cgaaaatcgt catcccacaa gtgacaaaga ttgttttacc
    22201 ttctgtaggg aatgaagtta tcaacttggt caaagattct tccttgatct atatattagg
    22261 tttaggtgac gtaatgcgtg ctgggaaaat cgcgatggaa cgcgacgcga ctttactgcc
    22321 tttgctaggc gtggcaatca tctatcttac attgactggt attctaacaa tcataatgaa
    22381 acaagttgaa ggaaaattaa attattaccg ctaactgata ggaggaagaa atatgattga
    22441 attgaagaaa gtgaacaaag catttggtga aaaaaaaata atcaaagatt tgaatctaat
    22501 cattccagat gggaaaacat tagctatcgt aggtccttcc ggtggcggta aaaccacgct
    22561 tttacgtatc ttggctggct tagaaagttc tgacagcgga gaattttatt tagacggtgt
    22621 accgttcaac ccattcgagc ttaaaatgaa agaacaagtt gtaggagtcg tattccaaga
    22681 cttccagcta tttccacatc tgaatatttt tgaaaacatt accttagcac caaaaatggt
    22741 attgaaacag acaaaagaag aatacaccaa aaaagcagaa gaattagcgg cttcattagg
    22801 gattagtgat ttattgaata tctatcctta tcagctttct ggcggacaaa aacagcgggt
    22861 agcgattgcc agagcattgg ctatgaatcc acgggtattg gcttatgatg aaccaacaag
    22921 tgctttagat cctgaattac gccagcaagt cgagcgtttg atcctatcat tgaaagaaga
    22981 tggggtaacc caaattattg tcacccatga tttagtattt gcagaaaatg tcggtgatca
    23041 attactaaaa gtttccccaa ttcattaaga aaggagaaga tagagatgaa aaaaaccagt
    23101 tttctattcg ctttgatcgc aggtcttctt ctttttgcag gctgttcgaa caaaaaaact
    23161 tcagcagata attgggcgac tatcaacgaa gagaaaaaaa tcgttatagg tttagacgat
    23221 acatttgttc ctatgggatt tagagataaa gacgggaagc tcacaggatt tgatattgat
    23281 ttagccaaag cagtctttga acaatatggg attacggtag actttcagcc cattgactgg
    23341 tcaatgaagg aatttgaact gaacaatgga acgatcgatt tgatatggaa cggctattcc
    23401 aaaacgccgg caagagaaaa gaaagtgcaa tttacaaaac cttatatgga aaacgatcaa
    23461 gtgctgatca cacctaaaga atcaggaatc acaaactttg gacaaatgaa taataagaga
    23521 ttaggtgcgc aaaatgggtc atctggttat gatgtattta cgaaacaacc agaagtatta
    23581 aaagagatag tcaaaaacca agatgctgtt ttgtatgata gttttaatga agcattgatc
    23641 gatctgaaaa gcagacgggt cgatggtctg ctgatggata aagtatacgc agactattat
    23701 ttgaaacaaa gaaacgaact agaagacttc aacataacaa aaggttctta tgagagtgag
    23761 gattttgcag ttggtgcacg caagtcagat agtacattag tgaaaaaaat caatgaagcc
    23821 ctagatcaac tagagaaaac aggtgaattc caaaaaatat ccgataaatg gtttggcgaa
    23881 gatgttacgc cgagaaatta acaaataggg gactgtgaca aaagacgtgt cacagtccct
    23941 ttttccgaat aaacagtgtt ctcctgccaa ctccttgtga ctcggagctg aatggcaggc
    24001 tcacaacctc ttggtaaacg gtgttcaaaa gccagttttt cggtattaag ccaaatttat
    24061 gcaaaaatgt agaaagccat tttcacaaaa tttttcttac tactcgaaac taagcgactt
    24121 tttcacaacc tcctttacat aattttattt tgttgtggaa ggggtttcgt gttattctaa
    24181 aagaggaacg attgaaggtt ataggaaagg aagagatgaa tggaacacaa agaacttacc
    24241 tcatttccaa aagattttct gtggggctct gcttctgcag cgtatcaagt agaaggagct
    24301 tggcaagaag atgggaaagg agaatcagtc tgggatcgat ttgtacggat acctggaaag
    24361 acatttaaag gaacgaacgg tgatttggca gtagaccact atcatcgtta taaagaagat
    24421 attgctttaa tgaaagaaca aggtctgaaa gcttaccgct tctctgtagc ttggacacgg
    24481 atttttccta atggacgagg agaagtcaat caagctgggc tcgcttttta tgagagattg
    24541 atcgacgaat tgattgaaaa cgatattgaa cctatgttga ctttatatca ttgggatctt
    24601 ccacaagcat tgcaagatga atataatggt tgggaatcac gtcagatcat tgaagatttc
    24661 actcattatg cagaaacatt atttgaggca ttccgcggga aagtccatta ctggattagt
    24721 ttgaatgaac aaaatatctt cacttcatta ggttatttgt tagcagcaca tccgccaggt
    24781 gtgacagacc cgaaacgaat gtatgaagtt aaccatattg ctaatttagc aaatgcatct
    24841 gtcatcaata aatttcacga gttagaaatg cctggaaaaa tcggaccaag ctttgcgtat
    24901 acgccaaatt atccaattga cagtaatcct gaaaatgttc tggctgctga aaatgcagaa
    24961 gacctgatgg ccaattattg gatggatgtc tatatgtggg gaaaatatcc gattgctgcc
    25021 atgaggttct tagaagaaaa aggatgggca ccaacgattg aagctggcga tgcagaattg
    25081 ctagaatctg ctaaaccaga ttttcttggg atcaattact atcaaacggc gacgaatgca
    25141 ttcaatccat taaacggagt tggtgctgga aaaatgaata cgacaggaaa aaaaggttca
    25201 tcagaagaaa ctggagttcc tggaatgtat aaaaaagttg agaatccatt tgtcgaacga
    25261 acaaattggg actgggagat tgacccagaa ggattaagga tcggactgcg tcgtatcaca
    25321 agccgttacc gcatgccggt actgattacg gaaaatggct taggagagta tgacaagttg
    25381 acagaagata aacaaatcca tgacgactat cgaatcaatt acttacaaag ccacgtcaaa
    25441 gccatcaaag aagcaatttc ggatggagca gaagtcctag gctattgcac ctggtcttat
    25501 acagatttgc ttagctggct gaacggttat caaaagcgat atggatttgt atatgttgat
    25561 caagacgaaa cacaagaagg atctttggaa cgatataaga aagacagtta ttactggtac
    25621 caaaaactga ttgaagaaaa tggagagaac ctttagttca catacttaaa acaagaaggt
    25681 acggctggat atggccgtgc cttttcttga taaaatcatt tagaaattaa gaaaaactgt
    25741 aaaataagct gaaaaatgaa agaaagcgtc agttctttca aacaaaactt tagttccctt
    25801 actttttttt gtataatgaa acttgatgaa atgagggata ataaatggca caaaagaaac
    25861 ggcctactaa aaaaaggaaa aagacgaaaa aaacgaaaaa gcaaaaacag cagcaggaac
    25921 aaatgctgac gattggtgtt gggtttgcct tgattttatt tgctgtcttc ggctttttaa
    25981 aattaggttt tttaggaata ttgattgcaa acggctttcg gatcattgca ggaaatactt
    26041 accaaatcct ctgtctttta ttagccgtat taggattttg gattgtcatt aagaatacag
    26101 agttttcaat tggtaaaaac cgacgctggt ttggcggcat actcttttat ttcggtatct
    26161 tattattgtt acatgcccat ttatttggca aactccatac tggggaacca aatatcatgg
    26221 ggacgacatg ggatttgtta gccagtgata taaaacaaag tcaagtagac aataacgttg
    26281 gtggtgggat gattggagca atcctttatc attttactta cttcttgatt gcacagcctg
    26341 gaagttattt agcagcagtg ctattactgg caggaggagc attcctgttc agtaatctgg
    26401 aaggctatca gctgttaaat ggtatccaat caattggaga acgagtacag gaattattgg
    26461 aaggtgatcc tgccaagcaa gctcgaaagc aagcggcaaa ggaagagaga atgaaacagc
    26521 gcgcagaagc gaaagaagca aggcgcttag ctgcaaaaga agctgcagaa aaagaagctg
    26581 cagaatatga gaagaaaaaa gcggtgagcc agcaaaggga aaatactgct gatgaatggc
    26641 aggaaccaga aaatacagag ccggagcagc taagttttgt tccaatcgac agttttcaag
    26701 aaaatatcca tcctgcgaat ctagagaaac cagtaccaga tacaccaaaa cagaccaata
    26761 cagcagaagg tttttcagat gagttgccag aggatgacgg tacctcatta gaatttgaga
    26821 ttgaagcaga acaggaaaat caagactatg aattaccgac agttgatttg cttgattcta
    26881 taccaactgt ggatcaaagt gatgagtata aaaaaattga aaaaaatatc ggcgtattag
    26941 aacaaacttt ccaaagtttc ggtgtcgatg ccaaggtcgt caaagccagc ttaggaccat
    27001 ccgtcacaaa attcgaagtc cagccggctg taggggtaaa agtaagtaaa attgtgaact
    27061 taacagatga tatcgcgctt gctttagcgg cgaaagatgt ccggatggaa gcaccgattc
    27121 caggtaaatc actgattggt attgaagtac caaatggaaa gatcagtatg gtttccttta
    27181 gagaaatcat cgaagcacaa ccaaaccacc cagataaatt actagaagta cctttaggac
    27241 gtgatgtttc tggacgggta caaacggctg atctttcgaa gatgcctcac ttactcgtgg
    27301 ctggttcgac tggtagtggg aagtcagtag caattaatgg gattatcaca agtatattaa
    27361 tgcgtgctaa gccccatgaa gtaaaactga tgatgatcga tccgaaaatg gttgaattga
    27421 atatgtacaa cggcatacct catctgttga cgccggtcgt gacgaaccct agaaaagcag
    27481 cgcaagcctt acaaaaagta gtacaagaaa tggaagaacg atatgaaaaa ttcgcggcaa
    27541 ccggagtaag aaatatttct ggttacaatg aatttgttca acagaaaaac ttggaaaacg
    27601 gaacgaaaca tccaacctta ccattcatcg tagtgatcgt agatgaatta gctgatttga
    27661 tgatggtagc cagcaatgaa gttgaagatg cgattattcg tttagcgcaa atggctcggg
    27721 cagcggggat tcatatgatc ctagctactc aacgtccaag tgtggatgtt atcacaggaa
    27781 tcatcaaagc aaatgtacct tccagaatgg catttgcggt atcaagcggt acagattctc
    27841 ggacgatcat tgattctaat ggggcagaaa agctcttagg gcgaggagat atgctattct
    27901 tgccaatggg tgagaataaa ccgatccgtg tgcaaggagc attcatttct gaccacgaag
    27961 tagaacgggt cgttcaattt gttacagatc agcaagaagc tcattatgaa gagaaaatga
    28021 tgccgacaga tgaagttgaa acgacaggtg ctccagaaca gccacaagat gagctgtttg
    28081 aagaagcaaa agcacttgtc gttgaaatgc aaacggcaag tatttccctt ctccaaagaa
    28141 gatttcggat cggttacaac cgagcagcac gtttagtaga tgaactggaa gctcatggag
    28201 ttgttggccc gtcagaagga agcaagcctc ggaaagtatt cattgagcag gaagaaacat
    28261 cagaaacgtt gccggacgat aatgacatgt aaaacttgtg tgatgaaggg ttgaaaaacg
    28321 aataaccaat aaaaagacaa ggcatgatga taccaaaaga aaaaatggtt tttttccatc
    28381 ttttctaata cggtatgatg tcttgtcttt ttagtttttg tgagattaaa gttctattcg
    28441 atttatttgt gaagtattgc attaaggaaa tgaatcatgt atagtatgta gcgaaacttt
    28501 gagaaaaaga gggaaaatac tttggaaaaa cagtccattt atggcttgac gaatgaagaa
    28561 ttaatcaatt ggtttataga aaacggcgag aaaaaattcc gagctgccca agtttgggaa
    28621 tggttgtatc aaaaacgtgt aagtaatttc acagaaatga cgaatctatc gaaacaattg
    28681 atcgaaaaat tatcggagca ttttatcatc aatcctctaa aacagatggt cgtccaagaa
    28741 gcttcggatg gtacagtaaa atatttgttt gaactccctg ataaaaacat gattgagact
    28801 gtactgatga gacaagaata tggcttgtca gtttgtgtga cgacacaagt aggatgtaat
    28861 atcggctgta cgttttgtgc aagcgggctg ctcaaaaaga accgtgatct gactgctgga
    28921 gaaattgttg cacagatcat gatggtccaa cattattttg atgagcgcaa tcttggcgaa
    28981 cgcgtttcac atgtcgttgt aatggggatc ggtgagccat ttgataatta cgacaatgta
    29041 atggactttt tgcatatcat caatgatgcc aaaggattgg caattggtgc tcggcacatt
    29101 acagtttcca ctagtggatt agcacacaaa atcaaggaat tcgctaataa cggcttgcaa
    29161 gtcaatctgg ctatttcctt gcacgcgccg aataatgagg tgcgaacatc gatcatgcgg
    29221 atcaaccgaa gtttcccaat tgagaaattg atggaagctg tggatgagta tttagagaaa
    29281 acaaaccgtc gaatcacgtt tgaatatatc atgttgaatc aagtaaatga tagaccagag
    29341 catgcgcaac aattagcaga tctattaaaa gataagaaaa aattagcata tgtcaacttg
    29401 attccatata atccagtcag tgaacatgat caatattctc gcagtccaaa agctgatgta
    29461 ttgagatttt atgatgtatt gaagaaaaac ggcgtaaact gtgtgatacg taaagaacat
    29521 ggtacagata ttgatgcagc ttgcggacaa ttgcgaagca agcaaatgaa aaaaacagtt
    29581 gccaaataat cgtatcctac tcgttttttc aattaccata aaaggagcag ttttcttaat
    29641 taaggaactg ttcaacttaa ataagagaaa agattctata gcgaaagcta taaagctttt
    29701 tttgacaaga aaaaccctca tcaagcaaag aaatgtcctc aatttgatga cagcctgctt
    29761 gatgggggtt ttagcaatta tttaactgat tttcttatat ccttgctggc tttcttgtgt
    29821 agcatgataa gtttctacgt caagaatggc ctgtttaaat ttttctcggg tgatttcata
    29881 aggcacatgt ttaatatcat ttgttgccat ggctttatct aagattgctt ctaaatcggt
    29941 cgtgacattg agattcatgt cggttaacga tactggaagt tggttctttt tcataaacac
    30001 atagatttta tcaaacaaat cgaactgctg atccatcatc aataaggtca gtacaccata
    30061 actgacagat gctccgtgaa ggtatccctc cattttttct agaacagtcg taccgtaata
    30121 gaatgagtgt gccatagcag aattatagtt attgttaact aaaacagaaa ccaatccggt
    30181 agtaacaatg atatccgaaa cgacttgttc aattgcatat gagggacgat cgtcggcact
    30241 atctttcaat gcttgcgtac cataagtcaa gagacgatca atgcacattt ttccgatttg
    30301 gattcctaat ctatccgtgt agcctagatc atcgccacga gcagaaaaag tagattcgac
    30361 ttctttggat aaagcatcgc caatacctgc ccataagtat ttatcaggtg cttcggcaat
    30421 aattgctgta tcaatgaagg tgtgtacagg tggttttgaa ggaaagaaga gtccgtccat
    30481 tacgccttct tcgttataga tgacacatac cgcagtgacg ggcgaacagt tcgaaccaat
    30541 agtgggaaag gtgaagactg gtttagctag tttttcacca atgactttta cagtatcgca
    30601 agcacggcca ccaccgactg caaacaggac gtctgctttt tggacacttt catgctggat
    30661 caactgttca atatttccat aagttgaatt acccccgtac cagagactgg cgacaacctc
    30721 tatttcctgt gtcaaagcta cttttatttt gttttctgcc tttgaaagtg cagtcttccc
    30781 tccaatcagc actacttttg tcccatattc tttgacgatt ccatttgctt tttcatacgc
    30841 atctgttcca atggtataat ttggtaagaa aacactttga ctcatattca tttccttctt
    30901 tcttcgttga aacgggttaa aattttaaag agtgatcgat ctgactgcgg ctgtagatgg
    30961 agtagaggtg aacctaagac aggataagtg atgaataagg tggcatgaac accttgaaat
    31021 catcaataag tatcctaaaa acgaacaagt acaaaaacat tgaaaacgac aataatgaat
    31081 ttttgttcct cttagtattt ctaccgattc cctttgcttt tttgtaatta tctaaaaatt
    31141 ctaaaaatta agattattat atgaaaacag gttttatttg tcaattcata attggttttt
    31201 tttaaagcaa aagataatct atatcatgat gaacaaacag agttttttcc tccaattgat
    31261 ggctttcctg atctttccta ttttgaataa agtgtttctg tataattttt ttattttata
    31321 agtaagataa ataatgaaag aatagagata ctgattggta gctaaagatt tttgagcgag
    31381 aacatttcgt tttttcaaaa ggactgttag aataagcaag aacaaggggg aagacgtatg
    31441 ataatcagtg aatttgaccg taataatcca gtattgaaag atcagctttc tgatttactg
    31501 agactgactt ggccggaaga atatggagac agctcggcag aagaagtaga agaaatgatg
    31561 aatccagaac gaatcgcggt agcagcggta gaccaagatg agttagtagg atttattggt
    31621 gcaatccctc aatacggtat cacaggttgg gaattgcatc cattagttgt agaaagctcc
    31681 cgacgaaaga accaaatagg tactcgatta gtcaattact tagaaaaaga agtagcttcc
    31741 agaggaggaa tcacgattta tttaggtacg gatgatttag accatggaac aacgttaagt
    31801 caaacggacc tgtatgagca tacatttgat aaagtggctt ccatccagaa ccttcgtgaa
    31861 catccgtatg aattctatga aaaattaggt tataaaatcg taggtgtctt accaaatgca
    31921 aatggctggg acaaaccgga tatttggatg gcaaaaacga ttattcctcg accaaattct
    31981 caataataaa aagaggttgt gacagaagta atcagcttca agaaataaga aggaatttac
    32041 gaaaattact tcttgaattt ttgtgaaatt ccaacttatt tccgaagaag ctacttttgg
    32101 aacaccgtgt accagaggtt gtgaaaaagt cgcttagttt cgagtagtaa gaaaaatttt
    32161 gtgaaaatgg ctttctacat ttttgcataa atttggctta ataccgagaa actggctttt
    32221 gaacaccgtt tattcagata agggactgtg acaagacttt tgtcaca
//
LOCUS       DAFTHM010000022        31840 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFTHM010000022 DAFTHM010000000
VERSION     DAFTHM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31840
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.022"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(151..2304)
                     /locus_tag="L7C88_001032"
     CDS             complement(151..2304)
                     /locus_tag="L7C88_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBP9557877.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2598..3446)
                     /locus_tag="L7C88_001033"
     CDS             complement(2598..3446)
                     /locus_tag="L7C88_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBP9557878.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="L7C88_001034"
     CDS             complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="L7C88_001034"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBP9557879.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPQMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5947..6126)
                     /locus_tag="L7C88_001035"
     CDS             complement(5947..6126)
                     /locus_tag="L7C88_001035"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBP9557880.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6173..7996)
                     /gene="cadA"
                     /locus_tag="L7C88_001036"
     CDS             complement(6173..7996)
                     /gene="cadA"
                     /locus_tag="L7C88_001036"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBP9557881.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8274..10553
                     /locus_tag="L7C88_001037"
     CDS             8274..10553
                     /locus_tag="L7C88_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9557882.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10646..11293)
                     /locus_tag="L7C88_001038"
     CDS             complement(10646..11293)
                     /locus_tag="L7C88_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557883.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11472..12191)
                     /locus_tag="L7C88_001039"
     CDS             complement(11472..12191)
                     /locus_tag="L7C88_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9557884.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12322..13473)
                     /locus_tag="L7C88_001040"
     CDS             complement(12322..13473)
                     /locus_tag="L7C88_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBP9557885.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13690..14430)
                     /locus_tag="L7C88_001041"
     CDS             complement(13690..14430)
                     /locus_tag="L7C88_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBP9557886.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="L7C88_001042"
     CDS             complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="L7C88_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBP9557887.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14814..15407)
                     /gene="yqeK"
                     /locus_tag="L7C88_001043"
     CDS             complement(14814..15407)
                     /gene="yqeK"
                     /locus_tag="L7C88_001043"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBP9557888.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15391..16041)
                     /locus_tag="L7C88_001044"
     CDS             complement(15391..16041)
                     /locus_tag="L7C88_001044"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBP9557889.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="L7C88_001045"
     CDS             complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="L7C88_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBP9557890.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="L7C88_001046"
     CDS             complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="L7C88_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBP9557891.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17484..18011)
                     /locus_tag="L7C88_001047"
     CDS             complement(17484..18011)
                     /locus_tag="L7C88_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBP9557892.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18191..18976)
                     /locus_tag="L7C88_001048"
     CDS             complement(18191..18976)
                     /locus_tag="L7C88_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBP9557893.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18969..19838)
                     /locus_tag="L7C88_001049"
     CDS             complement(18969..19838)
                     /locus_tag="L7C88_001049"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBP9557894.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19839..21218)
                     /locus_tag="L7C88_001050"
     CDS             complement(19839..21218)
                     /locus_tag="L7C88_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBP9557895.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="L7C88_001051"
     CDS             complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="L7C88_001051"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBP9557896.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21670..22146)
                     /gene="accB"
                     /locus_tag="L7C88_001052"
     CDS             complement(21670..22146)
                     /gene="accB"
                     /locus_tag="L7C88_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBP9557897.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="L7C88_001053"
     CDS             complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="L7C88_001053"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBP9557898.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="L7C88_001054"
     CDS             complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="L7C88_001054"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBP9557899.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="L7C88_001055"
     CDS             complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="L7C88_001055"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBP9557900.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25176..25400)
                     /locus_tag="L7C88_001056"
     CDS             complement(25176..25400)
                     /locus_tag="L7C88_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBP9557901.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25453..26415)
                     /locus_tag="L7C88_001057"
     CDS             complement(25453..26415)
                     /locus_tag="L7C88_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBP9557902.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26425..26865)
                     /locus_tag="L7C88_001058"
     CDS             complement(26425..26865)
                     /locus_tag="L7C88_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBP9557903.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27171..28136
                     /locus_tag="L7C88_001059"
     CDS             27171..28136
                     /locus_tag="L7C88_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBP9557904.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28193..28423)
                     /locus_tag="L7C88_001060"
     CDS             complement(28193..28423)
                     /locus_tag="L7C88_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBP9557905.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28509..29396)
                     /locus_tag="L7C88_001061"
     CDS             complement(28509..29396)
                     /locus_tag="L7C88_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBP9557906.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29485..30708)
                     /locus_tag="L7C88_001062"
     CDS             complement(29485..30708)
                     /locus_tag="L7C88_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBP9557907.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30725..31771)
                     /locus_tag="L7C88_001063"
     CDS             complement(30725..31771)
                     /locus_tag="L7C88_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBP9557908.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
BASE COUNT         8794 a         6970 c         5487 g        10589 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aaccaagaag tatttaatat
     2281 ttttttcata aaatctttca tcatttccta tccttccgcc tatttacatt catgcttcat
     2341 tgtacccaaa aacttcttaa taaaaaagaa aaaatgggcg gagcaagaaa ttctttacct
     2401 aatttcaaga taaaatcaac tttttgtttc acagcaatca cttaaagtta catatccaac
     2461 tatttttttc attaaaaaat aaacttattt ttgaaaatta tgttttctta agtcgtgaaa
     2521 cactttgatg gatcatttat ttgtggaaaa ctacgttttg ttattctaaa aaacttatat
     2581 aaaaaatagt aaggttttta tttcgaatcc ataaaatatt cttggattgc ttctcgtgtt
     2641 tttttcactt tttcgctaag cttttcgttt ttagccatat agaaataaaa aatgatatcg
     2701 atcgtagcaa attgggccaa aagtgaatta gttgccgcac ttcgattcgt gatttctttt
     2761 ggtctagatg tttgtacgag tacatcggct atcttgctaa gcgggttatt tccaaattgc
     2821 gtcaacgcaa tgatttcgat attcatgctt ttcgccagct cggctaatgc gactacatct
     2881 gcacttctac ctgagtttga aacaagccaa agcactttct ttttctcatt gctgacaagt
     2941 tgcgggagca agacgtggat atctttttca aaaatgattg gcttaccgac acgagaccat
     3001 ttttgcagaa tatcttctac tactaaagaa gaggcgccaa ccccatataa aaaaacagtc
     3061 tctgccgatt ccaaacactc tacgactttt tggatcgttt cttcttctag aatatctact
     3121 gtttctttta tcgctacttg tgcattgtta ccaagtttgt ttttgataga gtaaaaggac
     3181 tcatttgctt ctatatcact aaaaccttca tcgattccag tctgtagttc tgttgaaatc
     3241 gtgattttga agtccgtcag actttgaaaa ccgatttttt tggaaaaacg tacaactgtc
     3301 ggcgcactca acccggaagc ttctgctaat tcattagctg tcattgtagg gaccttctca
     3361 atattaccga taatgtagtt ggccaacttt ttttctgctg aagaataatc ttccatcata
     3421 ctttcaatac gactaattac gctcataagt tcctccaccc ttttaatgat agtctatgta
     3481 agtataccat atcagaccct tattcacggt cgtatactgg ataaaaaaca aaaaaacaat
     3541 ccgcccaaca gaatatctta tcccatcaat cccacagatt ctattgagca tctgtgtctt
     3601 tgaggaatac ctgttatcta ttgttcggat tgctttctat ctactacttt tttacaggaa
     3661 atttacctat tagttttctc tgctgtaatt tttgacttct gcttccatag catcaataaa
     3721 gatattcaaa tcttctacag ctgtttcttt acttccataa cgacgtacgt tcactgttgc
     3781 atcttccaat tccttgtctc caacaactaa ttggtaaggg atcttttgtg tttgagaggc
     3841 acgtatctta tagcccattt tttcattacg atcatcaact tctacacgca accccttcat
     3901 ttgcaaacgt tctttgattt cataagcata atcgccatgt gcatcaacag aaacagggat
     3961 gattgttgct tgtataggtg ccaaccatgt tggaaaagcg cctttgtata cttctgttaa
     4021 ataagcgaca aaacgttcca ttgtagaaac aattccgcgg tggataacta ctggacgatg
     4081 cgtattttcc ccgtcttctc caacatatgt caaatcaaag cgctctggca ataagaagtc
     4141 taattgtata gttgataatg tttcttctgt accaagagct gttttgactt gaacatctag
     4201 ttttggtccg taaaaggctg cctcgccttc tgcttcaaag taatctagtt ctaattcatc
     4261 catagcggct ttcagcattg cttgggcttt ttcccacatt gcgtcatcat caaaatattt
     4321 atctgtattg tttggatcgc gatagctcaa gcggaaacga taatctgtaa tattgaagtc
     4381 agcatatact gccaccatca attcaagcgt acgtttaaat tcatctttga tttgatcagg
     4441 acgaacaaat gtatgaccat cattcaacgt catttctcgt acacgttgta aacctgacaa
     4501 agcacctgat ttttcatagc gatgcatcat tcctaattca gcgatacgaa ttggtaattc
     4561 acgataagaa tggatcgtgt ttttgtagac catcatgtga tgagggcagt tcattgggcg
     4621 aagaacaagc atttcgccat ctcccatatc catttgcggg aacatgtctt cttgataatg
     4681 atcccagtgt ccagatgttt tgtacaactc aacatctccc attattggtg tatatacatg
     4741 ttggtaacct agactaactt ctttgtctac gatataacgt tcgatcgtgc gtcggattgt
     4801 tgcccctttt ggaagccaga atggcaaacc agaacctact tctggggaaa ccatgaacaa
     4861 gtcaagttct tttcctagtt tacgatggtc tctttctttt gcttcttcac ggagacggat
     4921 atattctttc aaagctttct tgtcaaaaaa ggctgtcccg tatacacgtt gcatcatttg
     4981 attgtttgag tttccacgcc aataagcacc tgccactgat aataatttaa atacttgtat
     5041 acggccagtg gatggaacat gtggtccacg acacaaatcg atgaattcgc cttgttgata
     5101 agcagtaatc acttcttctt ctggcaattc actaatcagt tctactttgt acggatcact
     5161 tgcaaaaatt tctaatgctt cctgttttga aagaacacgg cgttcgatcg gcagattttc
     5221 tttgacgatt ttcatcattt ctgcttcgat tgccggcaaa tcttctgcag ttacttggtt
     5281 ttgtccatta tctgtatcgt agtaaaaccc tgaatcgata gctggtccaa cgccaaagtg
     5341 gatatttgga tagaggcgac gcatggcttg ggccatcaaa tgagctgctg aatgacggac
     5401 taagccaagt gcatcttcat ggtctggtgt gatgatctca atacttgcat cttcctcgat
     5461 tggacgagtc aaatcaacga gttttccgtt cactttacca gctaaagctt tttttgctaa
     5521 gctttttgaa atgctttcag caattgccaa tgttgttgtt ccagactcaa attctttgac
     5581 tgcaccatct ggaaaagtaa tttttatcat aatagtttcc tccttgaaat gttttgattg
     5641 atcagatcat caagctgaaa aacaaaaaaa tcctagcatc tcttgaaaag agatactagg
     5701 acgaaaagtt cgtggttcca cctaatgttc aaacgcaaat gcgttcctca agcgttgtaa
     5761 cggtccgacc gcccttgctt caacaagggt ttcgaaagtg gtcatccttt ggttttctcc
     5821 tggaaaagtt tcagcctagc ttttcctctc ttatcgaaga ctctcaaatt cagttggctt
     5881 tctcatcaat caattatgtg tttatttaac cactaataaa tagaaaaatc aagtgggaaa
     5941 ctaaacttat tttttccatt ccccatttac accgtatgtt ccttttttca tctcattgat
     6001 gatgacatgg atgtgttctt ttggtgcctg cgtgttttta tgaacagctt ccgtgatatc
     6061 tttcatcata ttttctaatt gttccggact gcgaccttct actaattcga catgtacgaa
     6121 tggcataatg ctctctcctc tttctgatcg ttcttttttc aactcgattc tatcatacta
     6181 tgtttgtctt gggtactgaa tcaggaaaaa tggctggatc tttttttgct ctcaaggcac
     6241 tcaaaataga gaccgtatcc acgacttctt gcaaaacagc tccgaataat gcggggatta
     6301 gtcccgtact tgcaattaac atcaaaaaaa tacaaataaa gatgccaatc agtacagact
     6361 gtttcgctat tctcatcgta tctcttgaaa tcactactgc ttttgctaca cgcaagagat
     6421 catctttcaa gatgaccgca tctgcacttt cactagcagc tgtagaacca tgagccccca
     6481 ttgcaatacc gatatctgca gcagcaagtg ctggtgcgtc attcacgccg tctcctacca
     6541 tcgcaacagg tctttgatct ttagggatac tttctaaaat ggtcagttta tcttgaggca
     6601 agctacgggc atgtacagaa tctaattgga ctttttctgc aatcgtttga gcaatggcag
     6661 atccatcccc ggtgatcatc atcaaatttt tcacatcaag ttttcttagc tccttgattg
     6721 tctttgctgc ttctgggcga atctgatccg aaaataggat cgttcctgca aaagatcgat
     6781 caattgttac atagattgct gtattggacg tttctatttc ttcagctgaa acaaaagagg
     6841 cacgtccaat ctttacttca tgattattga ctactgcttg gattccttga ccggtcactt
     6901 ctttcagttg actaacagga tacagttggc tgtttttcac gttgttcact aacgaacgag
     6961 ctaagatatg gctagattcc tgttctgcac tagctgcata cagaagtagc tcttcttttt
     7021 ttattccatt gactggctga atcgcctcta cttccaatat ccctttggta agcgttcctg
     7081 ttttatcaaa agcaatcgtt tttgtacgtg cgagcttttc aatcgttgtt ccagttttta
     7141 caacgatccc gtttttactt gaacggctca ttcctgcaac taaagcaatg ggcgcagcta
     7201 gaatcagtgg acaaggtgat gccactacca gtacctcagc aaatcgtaaa gggtcttttg
     7261 agaaccacca agaaatacca ccgatcaaat aagcaatcaa cgtgaaaggg actgcataac
     7321 gatcagctaa acggacaaat cgggcaggct tttcttttga ttcttcgact agtttaataa
     7381 tcatttgata ctggctgtct gcggcacgtt tttcagcgat catttggatc gatccgtctc
     7441 catttaaaga ccctgacata atctgatctc caggtttctt ggtttccggg cgggactcac
     7501 ctgtcaaaga agattcatcg accgaagatt ctcctttggt cactcgacca tctgcgggta
     7561 caagttcgcc aggcttgact agtaactggt catcaatatt tatttcatcg attactatat
     7621 cctgcaattt tccttctttg aatcgatggg caattcttgg ggtgttatct aacaaagact
     7681 gcagttcttt acccgctcgt ttattcgcgt aatcctctag actatctccg cccgtaagca
     7741 tgatcaatat catcaaacta gcccagtatt ctttgacggc taatgttgca aggattgcgg
     7801 taatcgctaa tacatctacg ccatatcttc ctgaacgtaa cgtcttgatc atttccaaaa
     7861 acatcaagaa ggcgagaatc cctccagtaa atgcgacaat cgcaaatgca agggccggct
     7921 ggtgaaaaac aaattcactt aataaagcta tcccaccaat aagcaaagta agtaaaaatt
     7981 ttttgaaatg tgtcattgtt ttttctcctc ttttatgtga cttagagagg ttagtaataa
     8041 atttccagct gcctctttca tcttaagcat agtccttgac tagcactttt taaaacaata
     8101 ggccttaatt gaaaacaact atcactatca gcgtttccaa aattcatcag ttctacaaac
     8161 aaaaatattc agcaaggatt actttttcga ttcatcagtt aaaaagtacc ttttttcgaa
     8221 aaactatgct atacttttaa ttcgttattt acggcggaag gagcaaacat gcgatgaatg
     8281 agaaacaact agaacaaacg cacgtggatg aaacgatcga actaatccag atcgaacaaa
     8341 atatgctgga tacaaaacaa caagaattga ctcaggaaat gaatcattcg acaaaagaca
     8401 cagctaatca caagattcga gctggttcca atgaagcttt ttatgaatct gctgttgaat
     8461 atcgccaaca tgagcaggaa ttgcttttga aataccatac tcttgaagca cagcaaaaac
     8521 gcctgcaaac gttgtctgtc atgaaagata gtccttattt tgcccgtatc gactttaaag
     8581 aagaccgtga aacagaaaca ttatatctag gtatcgcttc tttaagagat ctggcagaag
     8641 aaacaatcgt tattgactgg cgcgcaccaa ttgccaatct ttattatgaa ggtgagattg
     8701 gtcccgcatt ttatgaaact gaaacagata gaatagatgt cgatctgcag ttgaaacgac
     8761 aatttaaaat ccaagaagga cgtattttat ctatggtaga tacgtcggaa gtaatcaatg
     8821 atgacttttt gctagagata ttggatgaat catcaagcaa ccatatgaaa aacatcgtct
     8881 ctacgataca aaaagcacaa aatgcaatca ttcgggacac aacaagtaaa gtaatgctga
     8941 ttgaaggaat cgccggaagt ggaaagacat ccgctttgct tcaacgtatt gcttttctgt
     9001 tgtatcataa tcgcaagtgg ctcgaggctg aaaacgttct tctattttca cccaaccatt
     9061 tgttttctga ttacatctcg actgtattgc cttcattagg tgaaagcggc gtgcctacac
     9121 agacattcaa aaattatttg gtgcagctgc tgccagagtt ttctttacta gatgaacagc
     9181 aacaagaaag tggttttttg ctaggggaaa aagatccgat acaagtgatg aaaagcggat
     9241 tgaccttagt cgatcagatt gatcgctata tccaaggcat cacaaactac ggtcccttgt
     9301 tccgtgatat gaaaataaat ggccgtacga tcctatcaaa ggaatcgatt cgccaatggt
     9361 ataaagaaac aaatgaacaa ttacctttac atcatagact ttctctatta caaacgaagc
     9421 tcctgaaaaa attaggcggt ctgcaaaaag acgaaacacg tcagcaatgg gtcaaagatc
     9481 tggcggaaga acagctccaa gaactatacg caacagatcc aaatcttgaa tatacagaac
     9541 aaaaggagcg ttcattacgt aaaaaactgg ccaaccaaat cgtacgtaaa agattccgtc
     9601 gaatccatcg agggatcatg aattatcaat ttgtcaatat aacgaaacaa tatctccact
     9661 ttctacaaac tgtgccactt tctcttctaa cacgacataa aatcagcgag accaggtggc
     9721 aggaacattt gacaactgtt cgtacacact tgcgtcaaag agaattgcgt caagaggatg
     9781 ctgtactatt ctttttactg atgcgccgaa catatccagt gacggttaca cacaaagctc
     9841 gctatatctt tattgatgaa atgcaggatt tcgcaccatc acaagtggca ttgctgcaag
     9901 ccttgttccc aaaagcaaat ttgactttct gtggagatct aaatcaaaat gtctttggaa
     9961 atgaaacgat cgttggatca ttggaagacc ttttcgtgga ccgtgaagtc actcgtttcc
    10021 aattaacgac aagctatcgc tccacaaaag aaatcactga ttttgctaat cattttattg
    10081 tgaaagaaca tcaagtagaa acaacagcaa gaaaaggaga ccttcctttg ctcatccaag
    10141 gaacaacaga tgatatcaaa ttgaattggt tagcagatac cattcgaacg actcagggaa
    10201 aagcccggta ttggcgtaca gcaatcatag ctaaaacaca agaagaatgc gaagctcttt
    10261 atgctcaact gccagacgag ttgaaacaac aagtccagct gattttaaat gagagtgact
    10321 ttatgaagcg ttccattatt ttacttccag cctttttagc aaaaggtctg gagtttgacc
    10381 gagttttctt gtgggatgta gatgcagaac atttttcttc tcagcaagac aaattgatcc
    10441 tttacaccat gtgtacacgt gcgatgcatg aattgaccct ttttacctcc aataatgaaa
    10501 gtcctttgtt aaacaatatg gatatttcat cttatgagaa aaaagtactg taagtaaaaa
    10561 gacaactgct atcattaatg ttagcagttg tctttttatt tacaataata attgcagaaa
    10621 aagtaattca atcatttaag gtcatttatt ctatatataa atccaaatct gtttcaggat
    10681 attttaattt gacaagcgaa ataatcattt tcagttcttc catgttttct ggatattctg
    10741 ggtcaaatac cttgctatga cggccaatcc cgccattgtc gatcaatcgg taaattcgat
    10801 tccattcaat gaattggtca attgattgga aattgctgat tggatagccg ccacaatcca
    10861 aaatctctga tacacgaaat gctaggtatg cactatcgat cactttattt tttttcgtgt
    10921 ctatcttctc atttctttcg ataagaattt tttcaggacg atgtttcaag ctccactcta
    10981 atagtagaaa gaaagcctcc atccgatact cttcttcaaa taaccgaaag gctgaatcag
    11041 aacgacgaaa aagcagcgga atcagataat tttgtctata aatcagcatt ggtgcgcggt
    11101 ccaccataca ctctaaataa cggttcagat accctgtacc gacatagttt cctaatcgat
    11161 agccttcaac gccgaatctt gcgtattttt gcgctaattt tgaacaatca gttacgttca
    11221 cagctaactc ttctactttg cggtaaccgc ttaagatacg ttcaaaaggt tctaaagtga
    11281 tttttgcttc catattcttc cccgtccatc ttccacatac ttcatatcat ttcacatgat
    11341 acttatgctc tcatcatacc acaggttgaa ttagaaaaga aaataaatca cacaaaaaag
    11401 caagacaatc tgttagtgag attgtcttgc ttttcgaaaa agactgaata cttttcgtta
    11461 aaactggttg cttagtcttc taatgccaca ttatggaaca catgctgtac atcttctaga
    11521 tcttccagtg catcaatcat tttttcaaat gtttcttgat cttctggaga tagtgttacc
    11581 tcgttttgag ggatcatttg gatctcagcg attgaaaaat cagtgattcc tttttctttt
    11641 aatgcttctt gtatactatg gaaatccgct acttcaccgt aaacgatgat ttgtccttct
    11701 tcttccatta catcgcgaac atcgatgtct ttttccatta ggtattcaag gatctcgtca
    11761 gcgtcttctc ctgcaaaagc aaagattgct gtattgtcaa acatgtaaga aaccgctccg
    11821 gaaacaccca tgttcccgcc atttttccca aatgctgccc gtacgtctgc tgctgttcga
    11881 ttcacattgt tcgtcaatgt atcaacaatc accattgagc cgcttggtcc aaatccttca
    11941 tagcgcaatt cagagtatgt ttcatctcct gcaccttttg ctttttcgat tgctcggtca
    12001 ataatatgtt ttggtacatt ataagtttta gcgcgatcaa tgacgaaacg tagtttttgg
    12061 tttgcatgcg gatcaggatc acctgatttt gctgccgcgt agatttcaat cccaaatttt
    12121 gcataaatcc ggctattatt agcatcttta gcagttttct ttgctacgat atttgcccat
    12181 ttacgtccca tattttcact tcgctttctg atttgatagt ttcataacgc aaaaacgtcc
    12241 tgttccatta tacttgtgaa tcacgattct gtgaagcttt ttttctttct tccttcattc
    12301 ttctcatttt tagtcaatta tctatactcg gattgggatt tgcccgaaat tctgttccgg
    12361 aatattgcct cccaattgat agatttgatc acttctaact aacagttccg cttcttgtgc
    12421 ctcttttttt ccgattcggg aataaataga aatctctttt ttttctttta agaatcttct
    12481 tccagcatcg gtaaatccaa gtagtcgaag ataattttta ttttgttgga caggaatctc
    12541 ttgctttttg atattcagca agacataaca agataatcgt tggatccgtg tccatgtata
    12601 tctttttgtt tttacctttg acacaaaatc ctcaaaacta tcagcagttg cagctgctgt
    12661 tttcatgcgc gattctattc cttcggtcat ctgatagata tctgtcagtt ccagcaaagt
    12721 agaagataac aaccgataac gcaaatacgg ccaataagat tcccaagtct gcagcgaaca
    12781 agttgaaaga tcttcttctg tctgaggcgg cacaagtcca gctattcttt ttccttcttc
    12841 taacgcatgg cgaatggctg ttgcactggc tatcctctga tctgtgatga ttttttcatg
    12901 atagcctgca cttttacgtc ggatcggatg taattccata gggtggacat acttggcatt
    12961 ttcctttgca taacttaatc ccaagatatg atttggcgaa gaaaaatcaa gcgtaatatc
    13021 gggatacaga ctgcgaaaaa cctcagtcat tttttgcgga taactatacg tttgatcaga
    13081 cagttcttga aatgcctctt ctatcctatc ttgattctct tggacaaagc gtccgaaact
    13141 gctgtaatca aacgaagtct cttcttctgt tccaaaacac aaactgtcac agtccagtgt
    13201 ttgcaagatt tttactgcac ctttagcaaa atagtcagct gactgaaccg cccattcgac
    13261 gggaagctcc actactaaat ccacaccatt ttgtaaagct tcattcgcgc gatgccattt
    13321 atcgatgata gccggttcgc ctctttgcaa aaaattcccg ctcattacag caatgacgac
    13381 ctctgctcct gttatttttc gtgccatttc cacatgatag cgatgtccat tgtgaaaagg
    13441 attgtactct acgataatcc cgcagctttt catgcgcatc ctccttcata gttatcgata
    13501 aaaaagaaat agagacaagt aaaaaaaggc aaaaatcgga aaaaataccc gaactatata
    13561 aactattctc gcaaacacaa tacttctgcg acgaaaagct gcactgcaag agcaatgcct
    13621 atatcgttcg gatatataat ttatgttgaa gatttattct tttcttgtta actcgagcag
    13681 gcaaaaccgc tagtctttgt atgctacaaa gaaccagcgc tttgatttct ctgatgctgc
    13741 ttcgtctgta aaatcagaaa atgcttcgac tttcgaaaag ccgctgtttt ccagcattct
    13801 taaataactt tccaatggat aggtacgctc ttgatgtagt tcatcttcac gaataaatcg
    13861 accagaccct tcttgttctt caacgaaaaa ggtaagaaaa tgttcgatgc tgtgtttctc
    13921 gcttcctgga taactatccc acaaaaaagc aaaattatcc ccttgataat gatagctata
    13981 ttctggaaaa acctcatcta cttgataggt ggagtgtacg tcaaataaaa atcggccatt
    14041 ttcttctaac gcttgataga cttcatcaaa cacttgctgt acctcttgtc tatttttcat
    14101 atagcacagc gaatcagaaa aacaggtaat tgcctgatat tgtccgattt ctgataaatc
    14161 gagcatattg ccttccacaa attggatcga tgcgtcttct tcatatgctc gctggctggc
    14221 aatcatcaac atctcttctg aaaggtctaa ccctgtcact ttatatccat cttttgcaaa
    14281 ggcaaccgct aatgctccag taccgcatgc cagttccaaa atattttttg tgtcttcttg
    14341 taaatgacgt ttcgaaaaag ctaaccattg ctgataaagt gtttcgtcca tcacttcatc
    14401 gtaaatgaaa gcaaatgttt cataagccat atgttaatcc aaccattcac taagatcgac
    14461 tagcggagca tctgaccata gtttttccag attatagaaa tttcgttctg gcgcatggaa
    14521 aacatgtacg atcacatctc caagatcgat caatacccat tttccgcctt cttttccttc
    14581 aatacgtttt acttcatatt tgttttcttc ttctttatca atgatttctt ctgtaattgc
    14641 gttgatttga cgttcgctat ttgctgaaca gatcatgaaa taatctgcca acaaggaaac
    14701 atttcgaacg tctaaagcga taatgtcttc tgcccgtttt gaatctgctg cttcaatcgc
    14761 aatttttaat tgttctttac tatctatgat gatttcctcc taatatgagc agcttatttt
    14821 tttgctaccc agtaattata tgtttcgatt gtttttggat aaatctgttg ttcttgcgca
    14881 agcaaatggg ccaatgtatg ttttgtttca aatgctacag cttcgtctag atcagcccat
    14941 gcaatggctc gtgcatcttg taccccagga aaatctcgac ctggttcaat atagtctgct
    15001 acataaatga ttttgtcaag gagactcatc ttagcagccc cagtcgtatg cacccggatt
    15061 gcatgaagaa tctctgcatc ggtgattcct aattcccgct ctacaaacga agcgccaaca
    15121 agaccatgcc agattgcatt attataattc aataactccg gatcaaaacc gtctcttacg
    15181 attaccattt tgaactcctc atctggtcgt tcttttgcat aatcatgtgt caatgcagca
    15241 atactagctt tttcaggaga agcaccgtat tttttggcaa gagccacggc tgtttcttct
    15301 actccaagca catgcttgaa gcgttgttcg ctcattctca tctgtatttt ttgcatcagg
    15361 ttttctctag aataagcagt atattcatta ctatagtcca tattcataca acccttcatt
    15421 ttgaatataa tcaattactt tatctggaac aaggtagcgg atagaacagc cttctttgat
    15481 cttttgacgt attttcgtgg aactgatgtc gatctcaggt acatctaccc aaattacagg
    15541 atatggagta tccgttgtgt atcctggtcg acgtataccc acaaagttga ccatagaagt
    15601 cagctcatcg attttatacc attttggcaa atattctacc atatccccac cgataataaa
    15661 gtaataatct gtatccggat tgttttgcgt caattccttc atagtatcat aggtgtaact
    15721 tttcccacca cgagctaatt caatcgtttc aatctgcaaa aaaggattgt cttccaccgc
    15781 taattccaac atgttgagtc gatgttttgc atcaatcgtc tgtttctcat caacatgagg
    15841 tggctgataa gaaggcatca aaaatacgcg gtcaagacct aaattccggc cagcttgttc
    15901 agccatcact aaatgtgcaa ggtgaacggg attgaatgtt ccgcccaaga tccctacttg
    15961 ctttttcttc tctaagaatt gaggcatttc ttcaggaaat aattgtgaac gaacaaatgt
    16021 cttagcttgc gtattcatca tggtcactcc ttatattgct tttacttctt ttgatagcct
    16081 ttgatacttt tcttttgtgg aaggtttgta taatacaata acacgtccaa tgatttggac
    16141 gatttcgcaa tctatttctt tttctaatac ttgagctgct tcttctgcaa tctcatctgt
    16201 attttgaagt aacgatactt tgatcagttc tcttttttct aaagcttctt caatttgaac
    16261 gatcattgct gaattgatcc caccttttcc gatttgaaaa atcggctgaa gatgatgcgc
    16321 tttgctacgt aaaaaacgct tttgttttcc tcttaaactc ataattttcc ttcttcctta
    16381 aatcaatgct ttgcgtttca atacatctac accctttggc gcccagcccg caattactac
    16441 tggcgctgtt acagtgatcc agcctagacc ggcaaaaacg atgtctgttt tttctttcac
    16501 agaaaactca aaacgaacaa gctccggaaa tgcctcgact tcatcaggac gaggaggctg
    16561 taataatcca cctacatgtt tttgataaaa ttcgtctgct ttttccagtt tcgttcgatg
    16621 aatatttaca tcatttgaca cataagcaat aaatgaagca cgattgccgc tgataaaatc
    16681 aaatcttgca agtccgccca agaaaagtgt ttgcccttca ttcagctgat aaactttagg
    16741 tttgatttct tttaacggtg caatgatccg caaatctttt ttacctaagt agtgcgccat
    16801 ttgatggcga tggataattc ccggtgtatc aatcaaaaaa tgcccgtcat ctaaaggaat
    16861 ctcgatttta tccaaggtcg ttcctggaaa ctgcgaagtt gtgattacat cttgtactcc
    16921 cgctgtattt ttgatgattt gattgataag cgtcgatttt ccgacatttg ttactccgac
    16981 gatatagaca tcccgtccat cgcggtattc ttcgattttt tctaatagtt ccgtcatctc
    17041 atgagatttc ttagcactag ttaataatac atctactgga cgaattcctg cttcgtaagc
    17101 acgttccttc atccattgtg ttaatttagt ttttttcaat gatttaggta atatatccac
    17161 tttgttccca actaaaagta ctggattgtc accgacaaaa cggtgtagtc ctgggattag
    17221 tgaaccattg aagtcaaaaa tatccaccac attgacgatc aatgcatctt tttgccctaa
    17281 ttcattcagt aagcgcaaaa agtcgtcatc cgtcaatgag acatcttggg tctcattata
    17341 atggcgtaat ctgaaacaac gctgacaata gacttccccg gaagctaaac ctttttccaa
    17401 agccgtttgc ggcgtgtatc ctaattcacc gggtttgttt gtttgtataa cggcaccaca
    17461 gccgatacat tgtaattctt ctgtcattcg attccacctc gccagcccat atcagggtgt
    17521 tttgctaata gataggccat aattcttttt tcccaaaaac gattaaattg tgtcttccaa
    17581 ctatctgttg cgataatggg ttttacaagg atgctacgta tccctgcacg attggctcca
    17641 cgtatatcag tcataatctg atcgcctacc attactatct catcatctgc taaatccaat
    17701 tgtttctttg ctatgttgat ccctcttgct aaaggtttca ttgctcgtgc aacatacaaa
    17761 agatcaaatt tttcaatcgc tcgcgcgaca cgttttgaat tattgtttga aacaacaaca
    17821 acagggattc ctgcattttt catttctaaa atccaagtaa gcaactcttc tgttccatct
    17881 ggattattcc atgcaatcaa cgtattgtct aaatcggtca atactgcttt gatgcctaga
    17941 ttctttaatt gggcaggtgt aatctgatag atggcttcta ccatccatgt tggtttgtaa
    18001 tttgaaaaca tgctgtctcc tcatctgcaa aaaatgaagg agcacataaa gtactcctca
    18061 accccgtatt atactgcata tcagcaaaaa aaactacctc tatactcgtt cgtctttcag
    18121 aaaaagcatt tctttacaaa atgaccaaaa ataaagattg atcacagaaa aatttagaaa
    18181 caaaaaacaa ctaatattgg cggaacctct tgtatcgttt ttccagtaat ttatgctgat
    18241 ctaatcgaac aagttccgtc aatctttcaa tcaacgcttt tttcataatg tgtgcgactt
    18301 tatatcgtgg caactgctcg ccgttgaacg tttcaggaat aactcgatca acgattccta
    18361 actcgcgtag ttctggcgca gtaattttca tcaactcagc tgcttctgcg gcgcgactac
    18421 cgtctttcca caaaatcgac gcaaatcctt ctggagaaag cacagcataa atcgtttctt
    18481 ccagcatcca gacttcatcc gctaaaccta gagcaagggc accgccactt ccaccttcac
    18541 caatgatgat ggcgatgatc ggtaccttta aatcagacat ttcgagcaga tttctggcaa
    18601 tagcctctcc ttcgccgcgc tcttctgctc ctacaccgca atatgcacct gctgtattga
    18661 tcaaggtaat caccggtcta ttgaactttt ccgcttgttt catcagtcgt aaagcttttc
    18721 gatagccttc aggatgggga gaaccaaaat ttctgcggat attttcctgc agatcccgtc
    18781 ctttttgaat accgatcact gttaccggtt tgccatctaa tcgagcgatt ccaccaacaa
    18841 tcgcttcgtc atctgcaaat aaacgatcac catggcattc ctcgaaagaa tcgaagatct
    18901 cttcaaaaaa atccaagctt gtccatcgtt ctttagctct tgctaactga acgacatcat
    18961 gtgctgtctt atccacgatc tatccatcct ttctgtgtat gcaattcaag aagcgtatgg
    19021 attttctgtt tcaattccat gcggggaaca atctgatcga caaaaccatg agataataag
    19081 aattcagcct tttggaaatc ttctggaagt tcctgcttga tcgtctgttc gatgacgcgt
    19141 cttccagcaa aaccgatcaa gctttggggt tctgctagaa taatatcgcc ttccattgca
    19201 aaactggcag ttactcctcc ggtcgtcggg tccgttaaaa cagttagata aaaaagacct
    19261 tcattgctat gccgtttgac agcagcagag atttttgcca tctgcattag agaaaagatt
    19321 ccttcttgca tccgtgcgcc acctgaagct gtgaacaaga cgactggaag actttccttt
    19381 gttgctcgtt cgaataatct ggtgatcttt tctccgacaa tcgttcccat acttcccatg
    19441 ataaaattag gatccatcac tccaataatg aagggaatcc cctgaatggt tgctttacca
    19501 gtgaggactg cttcatgaag tcctgtttta tcttgcattt ttttaatttt ttccgtatat
    19561 tcgggaaatg ctagcggatc tttggttaca agatccgtat cccattcttc aaaacttttt
    19621 tcatcaataa tcaaagctag acgctgccat gcaccgattc gaaaagcgta tccgcaatga
    19681 gggcatactt tttcttcacc gatgtctttc gtataaagga tatgtttgca atttggacac
    19741 tttgcccaca tgttatcagg aacagatggc gagttagcag gtttgctctc tctattagga
    19801 ttgatccgaa tatatttctt tttcttaaac agagccatct atgcgcctcc tatctccgtt
    19861 tctggtgtcc aattcggtaa aaattcttct tgtaaaaatg ctgtgctgta atcacctgct
    19921 atgactgcag gatgactaat caaatccatc tgaaattctg cgttcgtgat gattccttct
    19981 gtgataaatt cacttaaggc tcgctgcatc ttcattaatg cttcaaaacg cgtatttcca
    20041 tggacgatta tttttgcaat cattgaatca taatatggcg ggatcgtata tcccgggtaa
    20101 actgcactgt ctactcgcag tcccatccca cctgctggaa gcagtaagtt ttggatcttc
    20161 cctggagaag gagcaaaatg gaaagcagga ttttctgcat taatccggca ttcgattgcg
    20221 tgtccttgga atactacttc ttcttgacac acattcaaag gctcaccggc tgctatctcc
    20281 acctgttttt ttactaaatc gattcctgtg accatttctg ttactggatg ttccacttgg
    20341 attcgagtat tcatttccat gaaataaaaa tcgccttctt catccatcag aaactcgatc
    20401 gttccggcat tttcataatt gactgcttta gctgctcgaa cagcagcgtc tcctagtgct
    20461 tctctttttg tttgtgagat cactacagaa ggagattctt ccagtacttt ttgattgttg
    20521 cgttgtaaag aacaatctcg ctcgcctaaa tgaatgacat gaccaaatcg atcacctaag
    20581 atctgaactt ctatatggcg agcaggataa atgatttttt ccaaatacat atcatcattt
    20641 ccaaatgccg ctgctgcttc ttgctgagct gaagaaaaat gctgtgggag ctcttctttt
    20701 gattgaactt tccgaatgcc tttcccgcca ccacctgcag ctgctttcag catcactgga
    20761 taaccaattc tgtctgctat ttccaatgct tcttctactg tagataatac accagtactt
    20821 cctggaatga ctgggacatt tgcttcttgc atcaattgac gcgcattgat cttatttccc
    20881 attgcatcga tcgttgcact tttaggacca ataaatgtga tattgcactc ttcacacatg
    20941 gaggcaaatc ggctattttc agataaaaaa ccaaatcctg gatgaattgc ttcggctttt
    21001 gtcacgattg cagcgctcag tacttcctga acattcagat atgaatcaac ggcttttgcc
    21061 gggccaatgc agattgcttc atctgctaac tgtgtatgaa gtgcttcggc atctgcttct
    21121 gaatatatcg ctacggtttg gatccctagt tcgcggcatg cacgaatgat acgtacagcg
    21181 atttcaccgc ggttagctat caatacttta gaaaacatat ttcacctatc caatcataaa
    21241 ggttaattcc gcttcggcta cttttttacc gtctacttta gcgattcctt tgcctattcc
    21301 ggctgaagct ttcactttca atatctcaac ttcaaggtat aaggtatctc ccggtgtaac
    21361 tttcttacgg aattttgctt tgtccaatcc gccgaaataa gccgtctttc ccttgaattg
    21421 ttcaagagaa agtaatgcaa ctgctcctgc ttgagccatt gcttcaacaa tcaatacccc
    21481 tggcataaca ggttcttctg gaaaatgtcc ttgaaaaaag ggctcattga tcgttacatt
    21541 tttcttagca acgatccgtt ctccttcaac catttcttcc actcgatcaa tcaaaagcat
    21601 tggataacga tgtggaatga tttcttttat ttcttgtatg ttcattgttt tccctctttc
    21661 ctgctttgct tatttttgct gaatcctaaa gagtggctgt ccatattcga caactgactc
    21721 gttttctaca aggatttctg tgatcactcc gtcggcctca ctagttatct cattcatcag
    21781 tttcatcgct tcaataatgc agataacttc tcctttggca acttgatcac ctactttttt
    21841 gaaagctggt ttgtcgggcg ctggttgcag ataaacgatt cccacgattg gcgaaacaac
    21901 ctcgattcca tcaaatactg ccgattcttt ttctttcatt atttctggag cagttgttgc
    21961 ttgttcaggt atgacattga ctggctccga aactggcaac gtttcgtttg tttgaaccat
    22021 attcatgcct cgacttgttt tatttttatt catatacaat tcaaattgac cttcacgcaa
    22081 atcgaattcc gttagcgagg attgatcaaa ttgactgact aattctctga tttcattgat
    22141 atccaaaatt attcctccca gcgtttcatg cacagaaccg cattatgtcc gccaaaccct
    22201 aatgaattac tcattgcata agtaaaactt gcaggtttgc tttcgttttt gacaactgtc
    22261 aagtcaatct caggatcttg tttttctaca ttgatcgtag gtgggataaa ttgatgttct
    22321 aatgccagca aagttgccaa ggcttcgatc ccgccggctg ctcccaataa atgtccagtc
    22381 atcgatttcg tgctgctgac gtaagtatct ctgaaatttt cacctaatgc gatttggatt
    22441 gcttttgctt ctgcctggtc attggctggt gtacttgttc cgtgagcatt gatatatccg
    22501 acttgttccg gctgtacacc agcttcttcc atcgcaagct tcattgcttt agatgcacca
    22561 gaaccatctg gagtaggagc tgtcatatgg taagcgtcac agtttgcacc gtatccaacg
    22621 atttctccat agattttggc accgcgagct tgtgcatgtt ctaaagattc aagaactaga
    22681 acgcctgctc cttcacccat cacaaaacca ttccgatttt cgtcaaacgg aatcgaacca
    22741 cgattaggat cagttgattc tgagagtgct gttaaagctg caaatccagc aatccccatc
    22801 tcacaaatcg ttgcttctgt tcctccagca agaatgacat cagaatagcc atgtttgatg
    22861 ttacggaatg cttccccaat tgaattcgtt ccgctagcac aagctgttac gatagctgta
    22921 caaatacctt ttgcacctac acgcaaagca atatttccag ctgccatgtt ggcaatcgcc
    22981 attggtacga acattggaga aactcgtttt gcaccttttt catgtagacg aataacttgg
    23041 ttttcgattg ttggaagacc accgatccca gatccgatga tgacgccaaa ccggtcttga
    23101 ttcatttttt ctttatctaa accgctcatc tccattgctt ctaaagcagc gtagattcca
    23161 tagatcgaaa acatatccat tcgtttgcta tcttttttaa taaaatattt atcgtaaggg
    23221 aaatctttga cttcacccgc taaggtaatc cctgtttctg aagcatcaaa tttagtgatc
    23281 ggtgcgatgc cattcgtccc ctcttttaag ctattcaaaa agctgtctgc gtcatttcca
    23341 ataggtgaag tgactccata gccagtaatt accactcgat tcatttgttt gctctccttt
    23401 tcttatccgt gcatgaccaa tccgccatcg acattgatga cttgtccggt gatatatgga
    23461 ttttgtgcta agaaaactgc tgtttgtgca atatcttcta cttgtccgaa acgctgcatc
    23521 ggaatttgct tttccgcttg ttccttgact ttgtctgcta aaacttccgt catatcagtt
    23581 gtgatgaatc ctggcgcaat ggcattacat gtaatgcctc tagttgcagc ttctcgtgcc
    23641 acagattttg ttaatcctac tacgccagct ttactagctg cataatttgc ttgaccaata
    23701 tttccaatca acccagatac actagagaga ttaatgatgg ccccttctcg ctgcttcatc
    23761 atttttttca atacgtgctg cgtcatattg aaggttccaa tcaaattgat atccagacat
    23821 tttttgaaat cttctgcatc cattcgcatc acaagtttgt catttgtgat tccggcattg
    23881 tttactaaca catggatcga tccaagcttt tcttctgctt ctttgatcat ttgtcccgct
    23941 ttctcataat cagagatgtc accggaaact cctacgcatt ttacaccgaa tgcttcgatt
    24001 tcttctatct tttcttttgg aatctctccg cgaccattca aaatgatatt tgctccagct
    24061 tttgcaaaag ctaaggccat cgctttgccg attcctcttg tactacctgt gataaataca
    24121 ttttttcctt ttacatccat aacgttcctc cttatagtat tgctattgtt tcatcaaatg
    24181 tctgcttatt ctcaacacgc agaactggta ttgttttatc gatttttttc ataaatccgc
    24241 ttaatacttt tccggggccg acttcgatga cttgttcgat gccgattgtt tttaacttat
    24301 ggatactctc atagaaacga acaggttgca tgacttgctg ttcaagtagt cccgcgattg
    24361 tttctttctt cattatttcc gttgttgtgt tgcttatgat aggaaaagaa ggttcagaga
    24421 attgaatctg acttaggtcc ttcgccagtt tttttgctgc cggttctaaa atagctgtat
    24481 gaaaaggccc gctgacattt agagggatca ttcttttgaa ccctttttct tttaatagta
    24541 aaacagcttc gtctactgct ttttcttcgc caccaatcac gatctgctga ggtgtattat
    24601 aatttgcagg agatacgatg ccgtacttgc tagcttcatg acagctttcc tcgatcgttt
    24661 caatcggcgc attcatcact gcaaccattt tcccgcttcc agctggggca gcttctgtca
    24721 tataagcgcc tctttttgct actaacgcaa ctgcttcagt gaaggatagc gcattactag
    24781 ctactaatgc cgaatattct cctaaactca gtcctaaagc tgcatctggg atgattccat
    24841 gctccttcaa taagcgataa tacgcgatgc tgactgttag aatagctggc tgtgtatatt
    24901 gcgtctgatc caaacgttca ttttctgtaa agcaaagttc agccatatcg tagccgagaa
    24961 tctcacttgc ttcatcaaat gtctgcttta caacggcttc ttcatataaa tcttttccca
    25021 taccttgata ttgtgcacct tggccactaa ataagaatgc tgttttcatg tttttctcca
    25081 atatatccag aatatatgtt tgattcttcc tattcaaaaa ggccgagaca ttcctatttc
    25141 aggaaatgtc ccagccccca acctaatttt aatgattatg cagtttgttt ttctacgtaa
    25201 gtcactaaat cttgaaccgt tttgattccg tcttctgttt cgattttcac gtcaaattca
    25261 tcttcaattt cattgatgat ttggaataaa tccaagctgt cagcttctaa gtcttcttgg
    25321 atgtcagtag tcaatttgat ttcttcagtt tcttttccta attcttctgc gatgatttct
    25381 tgaatttttt cgaataccat aataatatat tcctccgata ttgtttgctt tttattttta
    25441 taatttaaca gtctacaact ccatgagaat acttccccat gttaaacctc cgccatagcc
    25501 tgtaaatatt actttctgct gttttcctaa ggtgatcttt ccactagaaa ctgcttcatc
    25561 caataagata gggatgcttg cagcagatgt attcccatat ttatccatat tggtcaggaa
    25621 cttttcttgc ggcatcttta cttttcgggc aattttctca ataattctga ggtttgcctg
    25681 atgcaaaagc agataatcaa ctggtttgtc tttcatgact tcttggatat tgtttgcaac
    25741 gtctcgtacg gcaaaatcaa aaatatctct gccagtcatt tgcaaataat acgaaccttc
    25801 tgaatcttct gaatagaacg gatttttatt ttgctggtag ccagcggtca atgagctact
    25861 tctggtaccg tcagctgcta atttttcttt cagcaatttt ttctgtggat tcgcttctaa
    25921 gagaatccca cctgctccat cgccaaacaa cacagcagtc gtacgatcag accaatcgat
    25981 tagcttagat agtgtttcac caccaatcac cagtccctta gttgagccgc agcggatcat
    26041 tttttcagcc atgcttaacg cataaacaaa tcctgagcac gcagcactga tatcaaaagc
    26101 gatagcatga gttgctccca atttcccttg tacttgtgct gctacagatg gtgtcgtgta
    26161 atcgggcgac attgttgcta ctaaaataaa atccaaatct ttagggttta gatttttctg
    26221 ttttatcaat ttttccgcca ctaaaatgca taaatcagaa gtctcctgat ttgttacaca
    26281 tcttcgttca cgaatacccg tccttgacga aatccattca tcagaggtat ccatcatctt
    26341 ggaaagatca ttattagtaa taatcttttc aggaaggacg ctggctgttg cagtaatcat
    26401 tccaaattgt tccattaaat atcctcactt atagtcttgc aagaagtcgt gcaagttttt
    26461 cagtgcatcc agcaaggcat gctgttcctc cgtagccatt ccgtctaaga tgttcttgac
    26521 catttcacga tgaaaatgct gatggacccg aaatagtaac tttccttttt tcgttagtcc
    26581 caactttaca acgcggcggt catcttcact gcggatacgt tcgacatagc ctttttttac
    26641 taacttgtta atagcagtgg tcaaggtccc aacagtaatt gatagttctt tggctacttc
    26701 tgaagttgtt tttttcttgt acatcccgat tgcctcgatc gtgtgcatct ctgtgattga
    26761 cagatctttg aattgagatt ttttcagctc agactcttcg attgtcaaaa tatcattgaa
    26821 gacactaaca agataatcat ttactgtttt taaatctggt tccatgttcc accgtccact
    26881 aattagtttg attatcaaat cttttgatgt tcaaactata tcttaacttt tttcaaaatg
    26941 caaccttaaa agatcatttt tttactatat gagctttttt taagatttta ctcatttaaa
    27001 acaactgata aatcagcatt tataatttct tttattagaa aaatcatcta tctcacatat
    27061 tttgattatc aaagtatttt ctgtgaacag aactatagaa ttccctaaaa cttgtccatt
    27121 atttcaaaat ttgttatagt ctttttattc aaagcgtaaa aggagatcct atgttaaaag
    27181 aaaaaatgaa aactctcccc atgctgccgg gtgtctatct tatgaaagac cgagatggta
    27241 aggtcatcta tgttggtaaa gcaaaacggc tcaaaaatag agtaagcagc tattttcatc
    27301 agaataaaca gcattcaaaa aaagtattac gtatgattca tcatataaca gattttgatt
    27361 tcgtcgtagt agacacggaa ttagatgctt tattgctcga gtgtcaattg atccaacatt
    27421 accgtccttt ttataaccga caaatgaatt atttcagtaa ttataattat gtacatatta
    27481 ccaataaggg atttgtatta acagatactc ctacggctcg aacatacggg ccttttcgtc
    27541 tctataaaaa aatgccgtct attttgcgta taatggaaga aacttatcaa atgccttggt
    27601 tgtctgaaat tagtttgtta gctttgcgag tccagcttcc tgacctacag gaaatgactt
    27661 ttgaacagaa aaaaaaggaa ctccaagggc tgtttcaagg ccgaaataaa aagctactga
    27721 cttacttgaa aaaaagacaa caacatttca tctatcagtt gaatttcgaa aaagccggta
    27781 tgcttcaaaa agatatcgaa ttagttactt attttattag acggatccag gaacaaaagc
    27841 agtttttaag aacaccatcg ctcaccttca gcatgccatt agcagcagat gagagtcaga
    27901 aaaagcacta cctcgtttgt tatggtcaac ttgcagaaac aatgattacc tctggtgacg
    27961 tttctcctga cttctattat gaaaagaaag aagctcattt atctttgaaa cgtcaattgt
    28021 caaaagaaga aatcgatcct gtacaaatct tgatcagtta ccgcaaaaaa ttagaaaaag
    28081 aacagtttga aattgaactg ttaaacaaaa aagaagctga aaagcaacta aattagttgc
    28141 ttctcggctt cttttaggca tcttcaactt caaatgtcaa ttatcctaaa atttattgga
    28201 ttaagtcata gatttccatc gctacgatat cgatattatc aaattcgtat tgctgatgag
    28261 tatctgtttc agttaattca aatgtatcgg tcgctttatc ataagttact gtacacttct
    28321 ctacgccttc tttttcaaaa cggcgaactt gcagttcatt atctgctgac tcgaccatag
    28381 cctccagtcg ttttatgatt gcgactaatt gtgaatgtgt catcggaggt cctccttttc
    28441 ttatttctgt tatattgtat caaaagcata gcctacttgc attgattttc tctaaaaaaa
    28501 ctcgtttttt atgatttttt ttctggtatt tttccttcag gccaccaaag tttgatcaaa
    28561 gcttgggttc cgtcattctc aaaaccttta tctgccaact cttcatatag tttcaatgct
    28621 tgggtagttg ctggcaatac aagatccatt ttttctgctt cttctaatgc aatctttaaa
    28681 tctttgataa aatgtttgac aaaaaaacca ggtgtgtaat cttcttttaa aatacgagga
    28741 gaataattgc ttaaagacca gttagctgca cttccacctg aaagcgtctc aatcactttc
    28801 tttaaatcaa gtccgttttt ttgtgcatag acaagcattt ccgtcattcc tgtcatcgta
    28861 cctgcaatca tgatctgatt agccattttt gtatgctgac ctttcccagc agaaccatgc
    28921 aatgtaaatg tcgtaccaaa ttctttgaat aaaggcagta cttgatcata aacggcttct
    28981 tctccaccga ccatgatcgt cagtgtacca ttctttgctc ctaagtcacc accggatacc
    29041 ggtgcatcta acgcatctgc gcctttttct tttgctgttt ttgcaatttt ttctgccagg
    29101 cttggtgtac ttgtagtcaa atcaactaaa atatgtcctg agatatctgc agaaaaaatc
    29161 cccgactgtc catagtagat ttcttctaca tctttggggt aacctaccat tgtaaagaga
    29221 atattacttt gttctgctac cgcttttggt gtatctgccc agatagctcc ttctgttact
    29281 aaaggatcag cttttgcttt tgtccgatta tagacagcta cttcgtgtcc tgcttctagt
    29341 agatggcgtg cgacagcact tcccatgacg cctgttccga taaaaccaag tttcattttt
    29401 tcgacctcct aaaaatcaaa aatccttgct tctatgctag tatacgctag aaacaaggat
    29461 tttttcataa aaaatgtttg aattttatct tttaaatgaa tttaatttta ttttgattcg
    29521 ttcaatcgag tcttcttctt cttttcttcg catctcttct tcatgataaa caaccatgtc
    29581 ttgataaaat tcgatcatag cttcgccgaa atgtgtagat gaaatatcat aaagtttagc
    29641 ttctaaaact tttggatctt taggaacttc actggaaata taatcaataa gtgctggtgc
    29701 aaagtcttcg tcggtttcaa aagttttccc taatgaagga tgatcgaaca atcggttcaa
    29761 ataagcattt ccttccacga cacaaggtgt tccggctgcc atcgcttctg tataagtaag
    29821 cccttgtgtt tctgaagtag aagcactgac aaaataatct gccgctttat aataaagtgc
    29881 tacatcattg ttgtccactt ctcctgtgaa ctgcacaaat tcttctaact gcagttctga
    29941 gatcaattcc tctaactctt ctacataagg tccttttcct acgataacta atctggcgtt
    30001 aggataagcg gagatgacct gaggaaaccc attaatcaag gcttggatat ttttctcata
    30061 agaaatcctg cttaaagaaa gaatcatcaa atggttttcc tgaagaccta gtgactccct
    30121 taatttgctg atatcctgct gagtgatatc agaacgtttg aatttttcaa tgtcgatacc
    30181 agtaggaatc acgcgaagcg gtgctattac accatagctg cgtaatgtat caataacacg
    30241 ttcacttgga caaactacac ctgtcgtatg atttgcaaat aatctagaca agtattttac
    30301 atgggattgc ctgatcactt ttcctttacc gatataatga aggtagtctt catacatcgt
    30361 atggtaagta tggatcagag gtattttcaa cttcttagct accatcttcc caagtatccc
    30421 tgctccgaat tctgtatggg tatgaataag atctagttct agttctttgg caaccaaata
    30481 agcataccac atgcctctaa caacaactct tcgatccttg aaagaaataa atggtacact
    30541 tggcattcga atcacatctt tttccaactt atccgcatta ggatcggtcg ttgtaaaaat
    30601 atagacttca tgcccatgtc tttctaattc ttgttttaat gttttgatcg atgtagcaac
    30661 tccgctgact tgcggaaagt aggtatcggt aaaaaagccg attttcatgt ttttcgcctc
    30721 caaactagtc cttgacctga tttacttttt ttaatttgct agagactttt tcattcagta
    30781 cactttcgta tacattttta agttcttcac cgattttatt gatacttcgc tcttttgctg
    30841 tttgataacc ggcttgtgtc gtactcggta gttcttgatt ggtaatctgt tggatcagtc
    30901 ggataaattc ttcgtttgtc ttccccatat agcagttctt gctatcttct aaccagccat
    30961 tatacactgg aatatctcga acaagtacgt tttgtttgct tgctaaagct tctaaaacaa
    31021 cgatcccttc tgtctcttca taagaaggga aaaagaatag atctgcacct gaatacgcac
    31081 cttctatgat ctctccacga atgtaaccag gaaacaggac attttcagga tgatcttctt
    31141 ttacaatttt ccggatgttc cgaggaatcg agtacatggg aacatgacca aaccaaataa
    31201 atgtgtattc gggcatcttc ttagcaattt ctacgaaatc aatgattcct ttacgttcga
    31261 aaaacaaacc gacacaaatg attacttttt gatccggaga cagtttgaaa tattctctga
    31321 acttttgttc tttcattgga tcagggtgat atttctctaa gtcgatccca ttggaaatag
    31381 cttgaatcgg cacacggata ccatagcttt ccaacaactg ttttgaataa ggtgttggcg
    31441 tgatcagata gtccgctttt tggtacaatc ctaccagata tttttttacg ataggagaaa
    31501 gctggttcga tccgataaag gaatttcgga aatcttcctc tgtagaatgc gcatgataga
    31561 caactttttt tccttctctt ctggctttat tgaccatatt atgactattg attccgtatg
    31621 tattgatgtg caggatgtca taatcttctt tttcatctag tgtataagag ataccgactt
    31681 ccgtcagagc acgtttttga tgatcaagcg cacgcccgat tccagatttt gcaagcatct
    31741 tttcactttc aaaatataat aataccttca ccttacgtcc cccttcactt atatagtata
    31801 acatagccta caaactgtca ctcaaactta agccctattt
//
LOCUS       DAFTHM010000023        31544 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFTHM010000023 DAFTHM010000000
VERSION     DAFTHM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.023"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..545)
                     /locus_tag="L7C88_001064"
     CDS             complement(<1..545)
                     /locus_tag="L7C88_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBP9557909.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVL"
     gene            complement(621..767)
                     /locus_tag="L7C88_001065"
     CDS             complement(621..767)
                     /locus_tag="L7C88_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBP9557910.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(871..1182)
                     /locus_tag="L7C88_001066"
     CDS             complement(871..1182)
                     /locus_tag="L7C88_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBP9557911.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(1184..1381)
                     /locus_tag="L7C88_001067"
     CDS             complement(1184..1381)
                     /locus_tag="L7C88_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBP9557912.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1775..3502)
                     /locus_tag="L7C88_001068"
     CDS             complement(1775..3502)
                     /locus_tag="L7C88_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBP9557913.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(3495..4688)
                     /locus_tag="L7C88_001069"
     CDS             complement(3495..4688)
                     /locus_tag="L7C88_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBP9557914.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4875..5519)
                     /locus_tag="L7C88_001070"
     CDS             complement(4875..5519)
                     /locus_tag="L7C88_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBP9557915.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(5613..5747)
                     /locus_tag="L7C88_001071"
     CDS             complement(5613..5747)
                     /locus_tag="L7C88_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBP9557916.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5749..7881)
                     /gene="feoB"
                     /locus_tag="L7C88_001072"
     CDS             complement(5749..7881)
                     /gene="feoB"
                     /locus_tag="L7C88_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBP9557917.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7878..8351)
                     /locus_tag="L7C88_001073"
     CDS             complement(7878..8351)
                     /locus_tag="L7C88_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBP9557918.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8752..8976
                     /gene="nrdH"
                     /locus_tag="L7C88_001074"
     CDS             8752..8976
                     /gene="nrdH"
                     /locus_tag="L7C88_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBP9557919.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            9135..11294
                     /gene="nrdE"
                     /locus_tag="L7C88_001075"
     CDS             9135..11294
                     /gene="nrdE"
                     /locus_tag="L7C88_001075"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBP9557920.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            11344..12309
                     /gene="nrdF"
                     /locus_tag="L7C88_001076"
     CDS             11344..12309
                     /gene="nrdF"
                     /locus_tag="L7C88_001076"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBP9557921.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(12398..13537)
                     /locus_tag="L7C88_001077"
     CDS             complement(12398..13537)
                     /locus_tag="L7C88_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBP9557922.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13846..14559)
                     /locus_tag="L7C88_001078"
     CDS             complement(13846..14559)
                     /locus_tag="L7C88_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBP9557923.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14813..15514)
                     /gene="nagB"
                     /locus_tag="L7C88_001079"
     CDS             complement(14813..15514)
                     /gene="nagB"
                     /locus_tag="L7C88_001079"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBP9557924.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15748..17280
                     /locus_tag="L7C88_001080"
     CDS             15748..17280
                     /locus_tag="L7C88_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBP9557925.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(17471..18673)
                     /locus_tag="L7C88_001081"
     CDS             complement(17471..18673)
                     /locus_tag="L7C88_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9557926.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(18755..19444)
                     /locus_tag="L7C88_001082"
     CDS             complement(18755..19444)
                     /locus_tag="L7C88_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBP9557927.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(19550..19918)
                     /gene="rplL"
                     /locus_tag="L7C88_001083"
     CDS             complement(19550..19918)
                     /gene="rplL"
                     /locus_tag="L7C88_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBP9557928.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(19971..20474)
                     /locus_tag="L7C88_001084"
     CDS             complement(19971..20474)
                     /locus_tag="L7C88_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBP9557929.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(20678..20805)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(20884..21573)
                     /gene="rplA"
                     /locus_tag="L7C88_001085"
     CDS             complement(20884..21573)
                     /gene="rplA"
                     /locus_tag="L7C88_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBP9557930.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(21677..22099)
                     /gene="rplK"
                     /locus_tag="L7C88_001086"
     CDS             complement(21677..22099)
                     /gene="rplK"
                     /locus_tag="L7C88_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBP9557931.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            22442..23110
                     /gene="sdaAB"
                     /locus_tag="L7C88_001087"
     CDS             22442..23110
                     /gene="sdaAB"
                     /locus_tag="L7C88_001087"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBP9557932.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            23123..23995
                     /gene="sdaAA"
                     /locus_tag="L7C88_001088"
     CDS             23123..23995
                     /gene="sdaAA"
                     /locus_tag="L7C88_001088"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBP9557933.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(24086..25105)
                     /locus_tag="L7C88_001089"
     CDS             complement(24086..25105)
                     /locus_tag="L7C88_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBP9557934.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(25278..26183)
                     /locus_tag="L7C88_001090"
     CDS             complement(25278..26183)
                     /locus_tag="L7C88_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBP9557935.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(26242..26787)
                     /gene="nusG"
                     /locus_tag="L7C88_001091"
     CDS             complement(26242..26787)
                     /gene="nusG"
                     /locus_tag="L7C88_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBP9557936.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(26888..27058)
                     /gene="secE"
                     /locus_tag="L7C88_001092"
     CDS             complement(26888..27058)
                     /gene="secE"
                     /locus_tag="L7C88_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBP9557937.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(27082..27234)
                     /gene="rpmG"
                     /locus_tag="L7C88_001093"
     CDS             complement(27082..27234)
                     /gene="rpmG"
                     /locus_tag="L7C88_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBP9557938.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            27396..28040
                     /locus_tag="L7C88_001094"
     CDS             27396..28040
                     /locus_tag="L7C88_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBP9557939.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(28096..28599)
                     /locus_tag="L7C88_001095"
     CDS             complement(28096..28599)
                     /locus_tag="L7C88_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBP9557940.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(28612..28658)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            29196..30161
                     /locus_tag="L7C88_001096"
     CDS             29196..30161
                     /locus_tag="L7C88_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBP9557941.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(30260..31432)
                     /locus_tag="L7C88_001097"
     CDS             complement(30260..31432)
                     /locus_tag="L7C88_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557942.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(31419..>31544)
                     /locus_tag="L7C88_001098"
     CDS             complement(31419..>31544)
                     /locus_tag="L7C88_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557943.1"
                     /translation="KLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
BASE COUNT         9714 a         6432 c         5512 g         9886 t
ORIGIN      
        1 aatagaacaa caaacatttg aatgattaaa aatattaaga caccaaacac aaaatgatca
       61 aatacttgat attgatgagc aacataagaa acaaataaac caattgtaag taaataaatc
      121 atgaatatag cagtaagttt agaactggac tgttcaacaa tcctatttat agctaatttt
      181 ctatataacc aaataaacat cagcaaaaac aaagaatcaa gcattatctg gaatactaca
      241 taaccatacc cttttatccc ttcaaatgaa aacatatacg tcataaccat ggaagtaata
      301 atagatctga aatcatcaat aagcatacat aatagtaatt tatttaaaag cactatatta
      361 gttttcttct tttcctttaa tataaaataa cttccgatta taggtatagc tgcggaaaca
      421 tcagtaaata attcaacaaa aaaagtgagt ggtatcaata aacatacaaa aagatatttt
      481 cttttgttaa gatcagtatt agtcatataa aataagagaa aaaagaaaaa gtttcccacg
      541 aacattctta atagataagc ttttgtatcg atagtaatca agagatcccc tcctgatttt
      601 aggatatcat aaaaaaaatt ttagttacac tttttaaata atgaaaaaac acattccact
      661 aaatttgatg ccggttttcc ttgaggtttt gttccagcac ctcctttaat ttttttaagc
      721 tcttgatctg aacattgttt agcatttagt ctattttttt cttccattac gattccccct
      781 acaaactata aatactttta tgtcactgat tcaatatacc tatttttcta atcaaaaaat
      841 tttgagacat atttaatatt ataagtatca ttaaaattga gatttatctc cataatctgc
      901 tcgatataaa ccatttattc cagcagttct tccaatttca ctcaaatttc ttattaattc
      961 ctcttgatat tcagtgaatc ttattttatt agtataagca gtaaaatata gataattcac
     1021 caatctattt attaaaggac cgggatctaa ttcatatttt tgtttttcta attttaaata
     1081 taccttttgt aaaacctcaa gaatatcaga atatttagga tctttactta tagatatatc
     1141 attatataat tcatgaacaa tttgcttagc attttttttc attttagcac ttccctggaa
     1201 ttgctccacc taaaaaacca cctatagaca ttcctgcaat acaagtagtt gccttggccc
     1261 aatcgaccgt acatttattt ttagtgcaat acactccatt tccataatat tttccactat
     1321 gagtggtacc cccatagata agttgtgtct ctttaataga caaaattttt aaatgtttca
     1381 taatctaatc acccctaaat taatgttttt agactattat tctaacattc attaaatttc
     1441 aaaaaacaat tccttcttga aacgtagcaa aataattcct gaataagaat ttaatcactt
     1501 ttaagtatat aaactatgta tattctttaa tattttttga gaatgcactt cgtacataat
     1561 aaactttaat cacattagtc tttcatacct acgatcgatc tctttgactc gcacccataa
     1621 attcataata gtttgtcggc gtctttggac gtttcgaaga tgagctacgc attctctttt
     1681 tttatagaca aaaaagatag agacgaacat ggagcttcca aatttggata tttgatccaa
     1741 ttttggaagc tccatttatt tcgtgtctgt ctttttattt tttccagctt tcgactaatt
     1801 cttggttctc tttgatccag tcttttgctg cttgctgtgg atcttttcca ttgttgattt
     1861 ccaacataac tttttccata tctttttctg accaatggaa attgtctaat actttgtaag
     1921 cttctggctg gtcttctttc aatccttttc gaaccatcgt atggatctgc tcttcgcttc
     1981 ccattccgtt ttcaggatct tctaagtatt tcagatcata tttggcaaac atccaatgag
     2041 gtgtccatcc tgtaactaca attggttcgt gttttttgat cgcttgacct agtgcaacgg
     2101 tcattgctcc tgaagaagat gtctctactt tccagtcttt caagttgtca tatttttgga
     2161 tcgtgttttc agcagccgta actacaccag ctcctggctc gattcctatg attttcttac
     2221 ctgcctgatc ggttaactca tcgatcgaat ttacatccat gtaggctggc actgctaaac
     2281 caacttttgc tcctgtcaaa ttggcaccta ggtcttcgac ttgatcttta tattgtgcat
     2341 attgtgaacc atgagtttta ggtagccaag ctgaaaccat ggcatctgac tcgccatttg
     2401 aaacagattt ccacatgatt gaattatcta atggcgtcat cgttacatca tagcccattt
     2461 gtttcaatac ttcaccgact acatttgttg aagcaacttc tgtatcccat tcaacataag
     2521 ataagttgat acgttttgtt tctttggcag atgaaaaact ccctatacca atcgcaccta
     2581 agatcactac tactacagca ccaatgatca gtccttgacg ttttttactt ttctgtgttg
     2641 ttgctcctgc agctttttta ttgtttggct ggttcaaatg ctgtgtaaaa cggtcaatga
     2701 tgattgctaa gataactaat gcaaccccgt tgacaaatcc attcccgact tgtgctcttt
     2761 gcaatgctga taatacgccg cgtcctaagc cgggtgcacc gatcatagag gcaataacga
     2821 ccattgaaag tgacagcatt gttgtttgat tgatccctgc catgatcgta cttttagcta
     2881 aaggcaattc tagtttgaat agtttttgac gacttgtgct cccgaatgaa tcagaagctt
     2941 ctactaattc tttaggaact tgtcgaatcc ctaaattcgt aaaacgaacg gttggtggca
     3001 gagcaaagat gactgaggca aatacccctg gaaccatccc gataccgaaa aatgcaactg
     3061 ctggaatcaa ataaacgaat cctggcattg tctgcataaa gtcaaggatc ggtttgataa
     3121 tactttgggc tttactgctt tttgccatca agatccctaa tggtacccca atgatgatcg
     3181 agatcacact agataaaaga acaagtgtga cagtattcat caaatcattc catagacctt
     3241 ggttataaat aaaccataga ccgattaatg tgaacaacgt aagtcctgga cgtttcttag
     3301 aaataaagaa agctgctacc gtcaataaca agataaacaa aggagctgga atcactaaca
     3361 gtaaatttgt aatccccgac atcactgcct gtccaatcgt ttgtaaaaat gaaaataggc
     3421 cagaaaaagt tgtcgtaaac cattctgtga tattttctac ccagtttgcc actggtaatt
     3481 gatagttcaa tagattattc atgttcactc acctcgcttg tttctgctaa tgcttcaatc
     3541 acactacctc ggatgacgac accttttaat tttccatcct ctacaactgc aagtggagtc
     3601 ggtgagtcat aaataatatt gaaaatatca cttaccacca tgtctttccc aatcaccgtc
     3661 acattttcat ctaggaagtc gatcaatgga cgtttttgct tcctagcttc taacgcttga
     3721 tctgcagtga tgatcccttt caggtgtctc tttctgtcaa cagccatcag catgctgact
     3781 tcttcattac gcatccttgt caatgcaacg tttggtccat cagattcgat attcgtcgtc
     3841 aatgcaggta ccatgatgtt ttgagccgta agcactttgg aacgatcgac ttcttccaca
     3901 aattcacgta cataatcatt tgctggattg gtcaatattt cttcacctgt tccgatctgc
     3961 atgatttcgc cgtctttcat caaggcgatt ctgtccccaa tccgtaaagc ttcattcaaa
     4021 tcatgggtaa tgaaaataat cgttttttga acattggctt gcaggtccag taattcgtct
     4081 tgcatttctc gccggatcag cggatcaaga gccgagaacg cttcgtccat cagcaagatc
     4141 tcaggatcat ttgctaaagc tctggctagg ccaacccgtt gttgcatccc accagataac
     4201 tgactaggat attggtcttt aaatgaaagc aaactagaat tttctaatgc tttttctgct
     4261 ttttcttgtc gttcttcttt aggtacacca cggacttcta acccgtattc tgtattttcc
     4321 aagatcgttc gatgtggaaa cagaccgaag ttttggaaaa ccatattgat tttatgacga
     4381 cggacttctc gcaattcttc tttgcttaac ttcgatacat cttctccatc aatatagata
     4441 ctgcccgaag ttggctcaat cagacgattc aatagacgga tcaatgtgga tttcccactc
     4501 ccggaaagcc ccatgatcac gaagatttct ccttctttta cgtcaaaatt cacgtcatac
     4561 acaccaaccg ttgcaccggt tttctttaaa atctccgttt tcggctggtg atcattcatc
     4621 atatctaaag cggcttgtgt ctttttacca aatatctttg ttaaatgttt tacttctact
     4681 tttaccaaac aaattctcct tttttatgta aattcatttt tctttctgaa aaaagtgacc
     4741 acactatgtt aacatcatgt agtcactttg tcaaaaatga aagaaatttg cttgtccaaa
     4801 ctgaaaaaaa cttggctaaa tctttgtaaa taaaaggttt agccaagtta atattttttt
     4861 aatatttcac acaatcattc tgcaagctga tgctccgggt aaaaaaagtt tgtcatacgc
     4921 tgtagtgtat attcatttcc aataaaatga acgatgtccc ctgccgtaaa tttagcatag
     4981 gggccaggtg aaacaagcag ttcttcatta tgagaaattg cgataactgt ggcgccagtc
     5041 gcctgccaga tattcaactc gctaattgaa cggtccagat gcattgcttt ttctgataaa
     5101 gataattcaa acggaagtaa aggattcatc ttatgtattc gcttcgtttg attgaccagc
     5161 tgatccaata attgagaaaa atgattcagc tcatcttgtt gcttctccac acttgccatg
     5221 atttctgctt ttgtatcttg gatggattgt acatcttgat attgcaatag gaaatctttt
     5281 gctttttcct tcgaagcaac aaatgcccca cttccatgcc gtacttccat gattccaaga
     5341 tctaccagca cattgatagc cttgcgggta gtctcaggag aagcattgta cgtactggca
     5401 agtgttgagc gggcatggat cttctcaccc actttatatc ggttttcaac gatacgttcg
     5461 gctaaatcaa cagcaatctg ctggtagcgc gggcggacga tttttttctt tccagacatt
     5521 ttctttcctc tttctttttt tactttccct catcttacta tgctctagca aaataagcaa
     5581 aaaaggggag aatagcctct tgcaacgact gatcatcgct tgatctgttc cttttttact
     5641 gggcaagctg tttgacagtc atcacaattc ttaccggatt ttaaacgagt atagacaatt
     5701 gcgcctgcac ttccaaagat taacacactt aataagaatg tcgccatcct attcctctcc
     5761 ttctaatgac aatatagtat aaaactggtt cttggatttt ggctgacgga acaaaacata
     5821 aacgagtcct atcatcagta aaatagcaag atacgtccct aacgctacct gtccaccctc
     5881 caataagtgt cccaactgat aaatcacaaa actaactaaa taagctaaac cgcattgata
     5941 gcctatggcg atccaagtcc atttcttggc attcatttcc cgatggatag ccccaattgc
     6001 cgcaaaacaa ggcgcacaaa gtaaattgaa ggctaacaat gaataagctg ctgcgggagt
     6061 atatgtgtgt tgtagcactt gccagatttc tctgccattt tcggatactt ccgcatgacc
     6121 aaacaaaata ccaaatgtgc caataatatt ttctttagcg accaatcctg taatcgctgc
     6181 gactgttcct tgccagtttc cccaaccaag cggctgaaaa acaactgcca ggattcgccc
     6241 gaaaaaggct aagatacttt ggtcttcaga aacaggttga gcataaaaat tataagaaga
     6301 gctgaaccag atcacgatac tagaaacaaa gataatcgtt cctgcttttt taacaaaaga
     6361 cttgctgcgg tcataggttt gtcttaggac cgctgaccat tgaggaaaat gatatgcggg
     6421 caattccatg ataaaaggag ctgtatctcc agcaaacaaa cgtgtttttt tcaagctgat
     6481 tccagagaaa ataattgcag tcataccaag aaaataggca gaaggagcta cccaagattg
     6541 atgaggaaaa aaggcccctg ctactaaggc aataatcggc aactttgcag aacaaggcat
     6601 gaaggttgtg accatgatcg tcaaacgacg atcttgctcg ttttcaatcg tgcgactggc
     6661 catgacgcct ggcactccac atcctgtagc aatcagcata ggaatgaagg attttcctga
     6721 aagaccgaat ttcctgaaaa gtcgatccat gacaaaagcg atcctcgcca tatatccgca
     6781 gtcttccaga aagctcaagc ataaaaacaa tataatcaat tgcggtagaa atcctaacac
     6841 tgctcccacg cctgcgatga tgccgttcaa gatcagctcc tgcatccatc ccgctacttg
     6901 ccattcagct aacaatctgc caacatgttc tggtaaccat gtaccaaaca atgtgtcatt
     6961 gatccaatct gtccccattg ttcctactgt ttgaatagcc agataataga tcagccacat
     7021 cacaaatgcg aagatcggca aggctaacca acgattcgtt gcaatctgat cgattttgtc
     7081 actcatcgat aattggaaag aatcatttga cacaacacag agtgtacata gttgggtaat
     7141 aaattcataa cgttcattga ccagaatcgt ctcactatcg tcgtccaata gtttctctgt
     7201 taactggatc agttgctcga tctctttttg ctgagaaact gctatctcgt aatcctctct
     7261 taccttctga tctcgttcaa aatatttcat tgcataccag cgtttcttgc cgctttgttc
     7321 tcctagtaca tcttcaattt catgtaaagc tgcttctaaa cgtggatcat atgtacaggg
     7381 aacaggaata gaaggccgct tttttgcaga ctcctgaatc ttttcgatta gtttttcgat
     7441 tccttgcttt ttcaatacgc tgattggtaa aactggtaca ccaagaccat aggaaagctt
     7501 ttctagattg attttttttc cttctttttt gatgacatcc atcatattca gaccaatgat
     7561 cataggaatg tctaaatcca ataactgcgt agttaaataa agatttcgtt ctaaattggt
     7621 agcatcaata atgttgatga tcagttcagg ctgttcctga accaaataat ctcttgcaat
     7681 cacttcttct ggtgtataag gagacaaaga atagatgccg ggtaggtcct gaatatgaat
     7741 gttcggattt tttttcaacg atccttcttt tttttctact gttacgcccg gccaattccc
     7801 tacatattga ttcgaaccag tcaagagatt gaacaagcta gttttcccgc tgtttggatt
     7861 tccgactaac gcgatattca ttctttttcc tccctttgta tcaagattag ttcggcctct
     7921 gactttcgta acgtcagttc ataccctcgc actgtcagtt cgattggatc tcccagaggg
     7981 gctagttttc ggataactat ttttacattt cgcgtcaatc ccatatccat taaccgtcgc
     8041 ttcactgcgc cttgtccgtg gattgctacg acgatcccag tctctcctgc ttttaattga
     8101 tcaagagaag tccagctttc agaggaagca gtctttttat tgacaaagat ttgacctagt
     8161 atttcccgac ttactgccac tcgatgactt tttaccagta aaatggcatt gttgcctgat
     8221 aaattgacga cgacgatttt acttccggca acgatcccga tattttgcaa atggcgtttt
     8281 gttttttctt ctgtttcgat tcgttcgact tgataaacga aattctgctt tgcctgcgct
     8341 aaggtctgca tattgattcc tctcttgtga aataaatcat gtattaaaat cattcattat
     8401 atgttctaat tttcttacgt gttacgcaaa taaatgagaa tcattctcac atagaatact
     8461 ctcggtaatt gagaatgtca attatacttg tgatattatg agcgaatctt tagtattgat
     8521 agataaaaat gagaaaaaaa tatttcttca tagttttcca caattttttc tctattaaat
     8581 ttgctatttt cccacacgat acttgttttc agctcttttt tcaaaaacac aaaacttagt
     8641 attccacagt ttccacaaca caatatgtag tgtttgttgt ttgacttttt tactaagagt
     8701 tttatactat ctattataga taataagaat gtgttagagg aggcactcac catgaacgta
     8761 aaaatctttt ctaaaaataa ttgtatgcaa tgtaagatgg tcaaacggtt tttaacagaa
     8821 aatcaaattg cttttgaaga agtcaatatc gatgaacagc ctgaagcagt agactggttg
     8881 aaagcacaag gattccaaag tgttcctgtc attacttctg atgcagaaac agttatcgga
     8941 ttccgtcctg atcagttgcg taaacttgcc agctaacatg actaaaagaa tcaaaacgtg
     9001 atacatggat ttgaagggct tgagacagca ccagtttttg tcgcaaactt ccaaatcctt
     9061 ttttaaagct taaaaacaat gcaatgattt gcaatcaagc atcatcaaat acgaaatgaa
     9121 ggttgggcgt acgtatgagt cttaaaaatt tacaagatgt cagttatttc aagctgaata
     9181 atgaaatcaa tcggccagtc aatggtcaaa tccctttgaa taaggataaa gaagctttag
     9241 ttgccttttt tgaggaaaat gtcaaaccaa atacgatgac ttttctatct attatggaaa
     9301 aaatcaatta cttgatcgat caagaatata tagaagcaga attcattcaa ttgtattcac
     9361 catcatttat tgaaaagcta tatcaatttt tggacgagca acatttttct ttcaaatctt
     9421 ttatggctgc ttacaaattt tattctcaat atgcgttgaa aaccaacgac ggttccgctt
     9481 atctggaaac ttatgaagat cgagtagcct tcaatgcgct ttactttgcg aacggggatg
     9541 aagaattagc acttgctctt gcagacgaaa tgatccatca acgatatcag ccagctacac
     9601 cttctttctt gaatgctgga cgtaaacgtc ggggcgaatt ggtgtcttgt ttcttgactc
     9661 aagtcactga cgatatgaac tctatcgggc gctcaatcaa ctctgctttg caattgtccc
     9721 gtattggtgg cggcgtaggg attactttat caaatcttcg tgaagccggc gctcctatca
     9781 aaggatatga gggtgctgca agtggtgtcg ttccagtcat gaaattattc gaagatagtt
     9841 tcagctattc taatcaatta ggtcagcgtc aaggagctgg cgtggtttat ttgaacgttt
     9901 tccatccaga cattattgct ttcctttcag caaaaaaaga aaatgcagat gaaaagattc
     9961 gcgtaaaaac tctttctctt ggcgtgatcg tacctgataa attttatgaa ttgacacgta
    10021 aaaacgaaga tatgtattta tttagtccat atagtgtcga aaaagaatat ggtgtcccat
    10081 tctcttatgt aaatattaca gctgagtatg atcatctagt tgcaaatcca aacattcgca
    10141 aacaaaaaat caaagcgcgt gatcttgaaa atgaaatctc aaaattacaa caagaatctg
    10201 gctatcctta cgtaatcaat attgatacag cgaaccgcga gaatccaatc gatggcaaga
    10261 tcatcatgag taatttatgt tcagagattt tacaagttca aacgccttct gtgattaacg
    10321 gcaaacagga atatgaagta ttaggaacgg atatctcatg taacttaggc tcgacaaata
    10381 tcgtgaattt gatgcaaagc cctaactttg gtcaatctgt gcgtacgatg actcgtgcat
    10441 tgacatttat tacagatgca tctgatatcg atgtcgtacc accgatccaa aacggaaata
    10501 agctgaatca tacgattgga ttaggtgcca tgggcttaca cacttatctt gcaaaagaac
    10561 aaatggaata tggctcagag gattcattag actttacaaa tatttacttc atgctgttga
    10621 attattggac acttgttgaa agcaacaata tcgctcgtga aagaaaacaa gttttccata
    10681 attttgaaaa atcagcttat gctgacggca cttatttcga aaaatacgta actggagaat
    10741 tccagccaaa atcagaaaaa gtcaaagcat tgtttgaagg catttttatc ccaactgctg
    10801 aagattggaa tgctttgaaa caagcagtaa tgaaagatgg actgtatcat caaaatcgct
    10861 tggcagtagc accaaatggc tcaatttcat atatcaacga tacgagtgca agtattcatc
    10921 ctatcactcg catgatcgaa gaacgccaag agaagaaaat cggtaaaatt tattacccag
    10981 cgccttatct atccaatgag acgattccgt attacacttc tgcttatgat atggacatgc
    11041 gtaaagtaat cgatgtttat gcaatggcac aacaacacgt cgatcaaggc atgagtttga
    11101 ctttattcat gcgttctgaa atcccagaag gcatttatga atggaagaca acaacgaagc
    11161 aaacgacacg tgatttgaat attttaagac attacgcttt ccacaaagga atcaaatcca
    11221 tttattacgt acgtaccttt actgatgatg cagaagaaat cggaagcaat caatgtgaaa
    11281 gctgcgtgat ctaatatcat agatagattc gcttattcat attttaatta aaggagcatt
    11341 ctcatgtcag aaacatatta tgaagcaata aactggaatg aaattgaaga tatcattgat
    11401 aaatccactt gggagaagct gacagagcaa ttttggctag atacacgtat cccactttca
    11461 aatgacctag atgattggcg tacattgtct caattggaaa aagatacagt aggacatgta
    11521 tttggcggtt tgacactgct agatactgtc caatctgaaa gtggcatgga tcagttgcgt
    11581 aaagatgtcc gcactcccca tgaagaagcc gttttgaaca atattcaatt catggaatcc
    11641 gttcatgcca aaagttattc ttctattttt agtacactga atacgaaaaa agaaatcgaa
    11701 gaaatttttg actggacaaa tacgaatcct tatctgcaaa aaaaagctga gcgtatcaat
    11761 gaaatctaca aacacggtac accgctagaa aagaaaattg ccagcgtctt tttagaaaca
    11821 ttcttgttct attcaggttt ttatactcct ctttattatt taggaaacaa caaattggct
    11881 aacgtagcag agatcatcaa actaatcatc cgagatgaat ctgtacatgg aacctacatc
    11941 ggttacaaat tccaattagg attcaacgag ttacctgaag cagaacaaga aacgttaaaa
    12001 gactggatgt acaatcttct ttatgagctt tacgaaaacg aagaacgtta tacagaagaa
    12061 ttatacgatc caatcggctg gacagaagaa gtcaagacat tcctacgcta taatgccaac
    12121 aaagcattga tgaacctagg gatggatcca ctctttccag atactgccaa tgatgtcaac
    12181 ccaatcgtaa tgaacgggat ttcaacaggc acaagcaacc atgacttctt ctcacaagtc
    12241 ggaaacggct atttgttagg tcatgtagaa gcgatgaaag acgacgatta tttgattgga
    12301 ttggaataag gatttatttt aattcaaaaa tttttcgaaa aataaaaaga gtttagcgta
    12361 cagatatttt aaatgtacac tgaactcttt tttatgctta ttcacttgtt tcttccagca
    12421 cttttggact gtctaacttt tccgaaacat gttccattct tctcaataaa tagattttcc
    12481 ggatatttaa tattatcgtc ttaatcactg catagacagg tatgcaaatc agcatgccta
    12541 atattcctgc gacacttcct gctccaatca ataccaagat gatcgtcaaa ggatggatat
    12601 tcattgattt cccaaataac aacggcttga tcaaatttcc atctaattgt tggatcacta
    12661 aaatcgacaa cgccatatac aaagcttgaa atggagagat aaacaaaccg acaatgattg
    12721 ctggtaccgc tccaataaaa gggccgacat acgggataat attcgtgatt ccgcaaatga
    12781 ccgcaagcaa caagctataa ggctgatcga atattctcat tgccaaaaag ctcattacac
    12841 caataatcaa agcatctaag atcgtactgc tgatataggc agataatgtt tcgtttaatt
    12901 cttttaccgt ttggcgtaac tctttacgaa tcgctttcgg aaagaagtga gacaacgcat
    12961 caataaattt gtgcccatcc ttgaacataa atagcaaaat aaatggaacg gtaaataaca
    13021 aaataaaaaa ttgcatcata aatgaaatga tttttgagac acttgcagat aaactgacta
    13081 atatgatatt gaacaaatta ctaagagata aatttgctga tgctaattgt tcttccaaat
    13141 tgaaattttt aaactcttcc cgctgcgcca attcatttaa ccatttgctt gtttcatctg
    13201 catacattgg caagctctgg gtcaattgaa ttgtctgttc cattaactga ggcactacat
    13261 tcatgacagt taaaacaact aaaatgatta cgaccaaaaa cgtcaataaa aaaccgaaca
    13321 ctctcgggat ccgatgcttt tcgagaaaaa caacgattgg atcgaacata taatagataa
    13381 aaccagcaac aagcaatggt aaaaaaactg ccgaaagcat tttcaatatt ggactaaaaa
    13441 tattcggcat ttgtaaaata aagtacacgc cgatgatcgt gagtactagc tccactgtcc
    13501 agaaaaataa ttttgattgt ttaaaacgtg attgcataca tctcctccaa ggtcctttga
    13561 tacttctatt ctatcattta acaaagagtt acgcgctgag attttcattt gcttaaaaaa
    13621 aacaaaaaaa ataaacatat tttaatgagt agacgagtac ttaaacaaaa acacggtttg
    13681 gagtagtgac aaaaattata ctgcagtccc tttttccaaa taaacggtgt tcaaaagctt
    13741 gcatcttcgt aataagccca gccaaacgaa aaatataagg aactattttt atttggctgg
    13801 gcttattact tgatgtagga catctatttt acaacctcag atcatttatt gcgcaatact
    13861 gactaaatgc aactttgtga tatttttgtg tacggacaac tcctcgatca catcggcata
    13921 agtgagccct tttggaagat caatcgtata gatatttttg tacactcggt agtcatcaac
    13981 gaattttacg tcaaaattca catcttcgat tacgatattt ttctcttcaa aataatcggt
    14041 aagaaaatct ttggtttctt ttctatggat aaattggatt tctaactttt tagtcgtagg
    14101 tacatggatc acgcgtttca ctactgtgag tgcaatagca atcccgataa aactgatgat
    14161 cgcaatggaa tagtaaccca tgccgatggc gatccctaat ccagcaattg cccataaaga
    14221 agcggcagtc gtaagtcccg tcaccgattg tttcgtgacg atgatcgttc ccgcgcctaa
    14281 gaaaccgaca ccactcacca cttgagcaat cagccttgct tcatctgaac gaatcgttcc
    14341 agcaagctgt ggatactcta aagcatctct taatgcacca ctagcgatct caacttggat
    14401 caatgcaatg atacatgctc ccatacaaac taaaatatgc gtacgcatac ctgctggacg
    14461 atttttatat tgtcgttcaa aaccgattgc tccgccaaat agcatagcga tccctaaacg
    14521 taaaataatc tctggaattg tcaataccat atcattcatc taaacaccct ccagtccaat
    14581 atatcatgtc tgaaaggagc agacaaaaaa agtgcaattt ttacctctta cgaaaaaagg
    14641 actgtgacaa aatttttgtc atagtccttt ttatgaataa acggtgttca atcagctgac
    14701 cctcggtatt actcaacaaa cggcaaaata tggggagcta tttttccttt gtcttctcta
    14761 atactcaggt caaaacgctg atttcacaac ctctttagcc tactattgaa aattacaact
    14821 tacttgctgc ttcttcatcg atgatcacaa caacattgtc gtgattttgc aatacacttg
    14881 ctggcaaatg attcgttaca ggtccttcaa tcatcccttt gattgcatca gctttgcttt
    14941 cgccaaatgc catcaagacg atttctttac ttttcataat tgaaccgatt cccattgaaa
    15001 cagcttttgt tggtacatct tctgctttat cgaagaatcg tttgtttgca ttgattgttg
    15061 attctgttaa gtcaactact gaagtcgttc cgtcaaatga agcaccaggt tcattgaaac
    15121 cgatatgtcc attttgcccg attcctaaga tttggatatc gattggatgt gcatcgatga
    15181 tttgatcata ctttttgcat gctgcttcca gatcttctgc ttttccatct ggtacaaacg
    15241 tttctttgaa tggtttttta tcaaataatt ggacatccat gaaatgacgg tagctttgtt
    15301 catctgaacc gcctagtcca acgtactcat ctaagtttac agaagtcatt tcactgaaat
    15361 ccaaatcgct tgaagtcatt tctttatata aagtaactgg tgtgcttcct gttgccaatc
    15421 ctaatacttt tgcacctttg ttcatacctt ctttgatgat ttcaaatgct ttttttccgc
    15481 cttcttcagc gttttttaca cgaatgattt ccatagtgat tgctccttta tattttggta
    15541 tagcccaatt atagcattct ttttttcttt ttacaataat tagtatagac caaattgcat
    15601 ttttttcatt ttcttgacaa taaataggaa tccgtgttag gtttcataag atggttcaat
    15661 caaacaatcc atgttgcatg aaaaccaagc aagtgattca ctgtggacgc tttatgtctg
    15721 cagttttttt atgaaaaagg agttattatg agtatactga cattaaacaa cattacccag
    15781 caatttggcg acaaaatcct ctatgaaggt gtcgatctgc aattaaatgc tggcgaacat
    15841 cttgggctga ttggacaaaa cggagccggt aaaagtacat tgattaaaat catcactggt
    15901 gagatcttac cagatgacgg acagatccat tggcaaaaaa atattcacaa aggttacctc
    15961 gatcaatatg tggaagtcga tgaaacatta acaatcgaag aatttctaaa aactgcgtac
    16021 gcaaaagaat acgaaaagga agaaaaaatt gcttttcttt accaaacata tagcgagacc
    16081 ttcgatgatt ccttgctgga aaaagctggg aaactccaaa cggaattaga ccaaggagtg
    16141 ttttatcaaa tcgacacctt agttgctgag atgagcagcg ggttggggat cgatgtctta
    16201 ggtttagatt cactgttgaa aaatctaagt ggtggacaac gttcaaaggt gattttagca
    16261 aaactacttt tagaaaaccc agatgttctg atcttagatg aaccaaccaa tcacttagat
    16321 gatcagcata tccaatggct gacgcagttt cttcaggatt ttgacggtgc gtatatcgtg
    16381 atttcccatg accaagaatt tcttgatcag atcaccaccc atatcgcaga catcgagttt
    16441 ggaaagatta ctaagtatac tggccatcta aaacaagcat tgaaacaaaa ggaacaaaat
    16501 cgcgaaagct atttgcgcca atatcatgct caacaaaaac aaatcgaaaa gaccgaagct
    16561 tatattcgaa aatacaaagc cggttcccga tcaacgatgg caaaaagccg acaaaaacaa
    16621 ttagataaaa tcgaacggct gacgcctcca gcttcagcaa gtaaagctgt ctttgatttt
    16681 ccattctcgc ctattgtcac gacattagca gtggaaacaa ctgatttagt catcggatat
    16741 gatcgaccgc tacttgcacc catcaatttg accatccgct ttggtgaaaa tattgccatt
    16801 cgaggcttca acgggattgg aaaatctact ttattaaaaa cactgatcgg tgagattgaa
    16861 aaaataagtg gcgatttcca cttcccagat aacacaaaaa tcaattactt ttcacaagat
    16921 ctgtactggg aaaatccatt agaaacacca ctacaatatt taagcagtca atttccaaaa
    16981 gcgactatca aagaattacg tcgccaacta gctaaagcag ggttagttaa tcaattagca
    17041 agtgaacctc tcactacatt aagtggtggg gaacaaacta aggtgaaact tgcacagttg
    17101 acaatgaacc aaggtaattt actgattctc gatgaaccga cgaaccatat cgatcaagaa
    17161 acgaaagaaa gcttacaaga cgggatacag aaatttccag gaacagtaat catcgtctct
    17221 catgaacaag aattttatca agatcttgtg caacgagtca ttgagattga accaaaataa
    17281 acgtttgatt gaatagttga aaaaaaggag ctgtgacaaa agttttgtca caactccttc
    17341 ttctgaataa atggtggcca attagctgac cttcggtatt agctcaaaaa acggcaaaat
    17401 atgaggagct atttttattt ggctattctt attacttgat gcagaacagc ttttcacaac
    17461 ctcttttcgt ctatttttta ttttcgagat ttctctttcc tttaaaaaca actgtttgaa
    17521 agaagaacgc acatccttga aaaacaagcc cgctaaccgt tacacctaac cagccatact
    17581 gctgccacat tgtcgtccct agcaatgaac cagccgcacc tccaataaag tacataaaca
    17641 taaatacagt attatttcgg ttgcttgctg cttcacctag cccttgtact cgtgtttgat
    17701 tggcgacttg accaaattga ttcccgacgt ctaataaaat aatagctaaa agcaaaatgg
    17761 ccaaatggct tccgccaacc aataaagcaa taaagcttat tgtttgcata acaagtccca
    17821 tatacacgat ttttctttca gaataagaat ctgccagtcg tcccacgata ggtgcagcaa
    17881 ctgctccaga caaaccaaaa atcgctaata tccctgcttc gaatgttccc caattgtagg
    17941 cgggactgct gatataaaaa atcaacgtag accaaaagat cgaaaatgtt ccaaacatga
    18001 aaaatccact gactgccgct tctcttaata gacgttgaga agcaactaaa tgcggcaaac
    18061 ttttaagtga atcaaggtat gaaacagctg tactactttg ctggacagaa cgcggcattt
    18121 tccagtaaag cagaagtgta agaattccga ctgcacataa agcaaataaa tagatcatcc
    18181 gccaagaaaa aagactggca acaataccag ataccgtccg agaaagcaaa atccccacga
    18241 gtaaaccgct aagcaatgta cccatgacct tccctcttgc ttttggtccc gctagtaccg
    18301 caccgtaagg aatgatgatt tgcggcacga tcgaaagtaa tcctattaaa aaagaagcgc
    18361 atgcaaataa cgtaaacgaa ggcgcaaaaa aagcggccaa cagagagacg gcagataacg
    18421 ctgccattcg aatgatcaat tttggacgat ccaccacgtc ccctaaagga actaaaaaca
    18481 gtaaccctaa cgcatagcct aattgggtca acatcgtcaa tatcccgact gcacttgtgc
    18541 taacagataa actagctgct acttttgttc caatcggctg gatgtaatac atattggcaa
    18601 caacaacgcc acaagtgatt gataatagta aaataagcga agttgttaaa ggtttttttt
    18661 cattactctt cattgatttc ccccatttcc tatcttagtt tacaacttat ggaaaagatt
    18721 ggaaatagaa aaatacaact attcgccaca cttattattt gtgcttttgt tttccttgtt
    18781 ttttcttgcg atctttataa atgaagacaa ctaaccctac tagcacagta acacttgcaa
    18841 ccaacgtgac tgcagttttg ttatatccgt gaaacagagc ttctccacca cacgcataca
    18901 acacagacga agggatgact ccaatcacga tcgacaatat gatttgctgt agaggcaatt
    18961 tcatcgcatc tgcagcaaaa ttgaccatag aagatggaat aaccggtatc atatagccta
    19021 acattacacc tatttttgga tgtttcattt gtcggattgc ttgcacccaa tgattcgttt
    19081 cggttttctt atctaaaaat tttaagcgat gcataaggaa aattgcagtg atgttaccaa
    19141 gagcattacc caaaatgttg atgatcgcac ctgtcagtgg tccaaagctc aaaccagcaa
    19201 tgactccaac tactgaagta ggaatacctg gaacagcaca catcaccgct gtcaatacga
    19261 tcaagagtat cgatgcaaaa gtcccatgcg aacgaatatg tgcgagtagc tctgccttac
    19321 tcgctctcgg atttaaaaat aattggatgt ctgtctgata ttctaaatac aaccgatagc
    19381 ccactaccag tatcagaatg attcccaacg agatcaatat caatcggatt attttctttt
    19441 tcatatttcc tcctgaaaaa aatctatatt cattaaataa tagtttaaca taaaaacaaa
    19501 aaagcaccga aatccaacat aggatctcag tgcttttaaa tagtaaaaat tatttaacag
    19561 ttacagatgc gccaacttct tcaagtttag ctttcaattc ttcagcttct tctttagata
    19621 cgccttcttt aactggtgca ggagcgccat caactacagc tttagcttct ttcaagccta
    19681 aaccagttgc ttcacgaact gctttgataa ctttaacttt ttggtctcca gctgcagtta
    19741 attctacagt gaattctgtt tgttcttcag cagcagcagc gccaccagca gcagctacag
    19801 ctacaggagc agcagcagat acgccaaatt cttcttcaat agctttaact aggtcgttaa
    19861 gttctaggat agttgcttct tttaactcag caacgatgtt ttcaatgttc aatgccatta
    19921 taatttcctc cgtttaattg ttctttttta tttaatgctt tatgcggcaa ttaagctgca
    19981 tctccatctt ctttgtctgc cactgctttg acagcgtaag ccacgttgcg gactggcgct
    20041 tgtagtacag atagcaacat agatagaagt ccttcgcgat ttggcaattt tgccaatgct
    20101 gtgatttctt ccaatgaaga gactttacct tcgatgatac cgcctttgat ttctaatgct
    20161 tttgcttctt tagcaaattc gtccatgatt ttcgctggtg cgactacatc ttcgttactg
    20221 aatgcaacag ctgtaggtcc agtgaatact tcgtccatgc cttcaaggcc agctttttta
    20281 gctgcacgtg aaagaataga atttttgata actttcattt ctacgttagc atcacgaagt
    20341 tgtttacgta aacgtgttac ttcatcaact gttaatccgc ggtagtcaac gactactact
    20401 gatgcagctg ctgtaaattt ttcgcttact tcatcaacga ttgctgcttt ttttgcgata
    20461 attgcttcac tcatttttga gtttcacctc ctgaattttg atggaagagt tttttgcact
    20521 gaaaaggcaa gtcactttta tagttacttt gctcaaccag tattattcat cacctattca
    20581 cttcgttcat agtgattcta ctcgctttgc tcgaaaggaa actcctttcg ctttgctcaa
    20641 ccagtattgt tcatcatctc ttcacttcgt tcatagtgat tcacaataaa aaactctatg
    20701 ccaccgcaga catagaggga ctattgaata tattcaataa acgtcctcgg taggaaatta
    20761 aggcttgatg ccacctactg tcttcggtac aagttaatta ttaacctcaa ctagcttagc
    20821 atgctaaact agttgagtca agaattattt ttcagttgga tcaatcaaca ttctaatatt
    20881 taattagaaa gaagcttggt caacatggat accaggtcca aatgttgttg tgatcgttac
    20941 atttttcatg tattgacctt tagctgctga tggtttagct tttagcaata catcatggat
    21001 tgctgcaaag ttttcaacta atttttcatc gtcaaatgaa acttttccga ttggtacatg
    21061 gatatttcca gctttgtcca cacggtaagt tactttacca gctttcactt cgtttactgc
    21121 ttttgttacg tccattgtaa ctgtaccagt tttagggttt ggcattaagc cttttggtcc
    21181 taatactcgt cctagacgac ctacagtagc catcatatca ggtgttgcaa caactacatc
    21241 aaagtcaaac catccgtttt ggattttttg aaccatgtcg tcgtcaccta cgaaatctgc
    21301 accagctgct tcagcttctt ttgctttgtc tcctttagca aaaactaaaa cagtttgtgt
    21361 tttaccagtt ccgtttggta atacaacagc accacggatt tgttggtctg cttttttagg
    21421 gtctacgttc aaacggtatg caacttcaac tgttgcatca aattttgcaa tgtttgtttc
    21481 ttttgctaaa gctactgctt cggcaacagg ataaacttta cttgaatcaa ctttttttaa
    21541 tgcatcttgc atttttttgc tctttttagc cattttggtt cctccttgat tgtggttata
    21601 acggttgtac ctcccacgtg ttctatatct ttcaatatag agccaactga gaagctgctg
    21661 tcttagggtg tatagattat tctacagtga tccccatgct tcgtgcagtt ccttcaacca
    21721 tgcgcattgc tgcttcaacg ttagctgcgt ttaggtcttc catttttaat tcagcgattt
    21781 ctcttacttg atcgctagaa actttcgcaa ctttattttt gtttggttcg cctgaacctt
    21841 tttcgatttt agctgctttt ttcaatagaa cagcagctgg cggtgttttt gtaacgaatg
    21901 tgaatgaacg gtcttcgtat acagaaataa caaccggaat gatcaaacct gcttgatcag
    21961 ctgtacgagc gttgaattct tttgtgaatc ccatgatatt gatacccgct tgacctagtg
    22021 caggacctac tggtggagct ggagttgctt tacctgcagg aatttgcaat ttaacgattt
    22081 tttctacttt ctttgccacg agacatacct ccttaagtcc gtgatgtggt taattggaga
    22141 tgcatatttc tcctcccacg ttttatctga tctgaaaaaa tccagacaaa taatgtgcaa
    22201 aacaatgcac actggtacag tatagcaaat ttatttgttt tttcaagatt tttttctgct
    22261 atttttacat tttgcttgaa taaacgctaa atttattcta aaaaaacaac aatttttcgt
    22321 tctcatttct tcttttatgt tacacttgcg ctagcatggt tcaacagatg aaagcaaaca
    22381 ataacacggt tttttagacc cttgtacaaa gattcctaca taacaaaatg aggtggagaa
    22441 aatgaaagat ttaaggtata gaagtgtctt tgatattatt ggacctgtga tgattggtcc
    22501 aagtagctct cacactgccg gagctgctag aatcgggaaa atcatacgta gtatatttgg
    22561 cgaacagcct gattctgtag atatttatct atatgaatca tttgcaaaaa cctatcgggg
    22621 gcacggaaca gatattgcat tagttggcgg cctgttaggg atggaacccg atgatgaacg
    22681 tttagctgat tctttgaaat tggcatatga agccggtatg gaagtcttgt ttgttcctaa
    22741 gagtgaaaaa gccgaacatc caaactctgt aaagatgctt ctaaaaaaag gaacacgaaa
    22801 gctttcagtc actggcattt cgatcggcgg tggcaatatc cagatttctg aattgaatgg
    22861 attcaaaatt tctttaagca tgggtactcc taccttgatc gttgtccacc aagatgttcc
    22921 aggtatgatt gctaaagtga ctagtatact ttctgagacc aatacgaata tcggcactat
    22981 gacagtgaca cgggaatcaa aaggtgaaaa tgccattatg ataattgaag tagatgatcc
    23041 tcaagtagaa gaaacggtaa aaagactcaa acagctgcca aatatcgaca gcgtaaatta
    23101 tttcgattaa ggagctaaaa aaatgttttt atcgattgaa gaattagtag atcaagcaaa
    23161 agcttatcca agtgtagcag aattgatgat tgcagttgaa atggaaatga gtggccgttc
    23221 ccgtagtcac atcatcgaga tcatggaaaa aaacctctca gtaatggaac aatcaatcaa
    23281 cgagggaaaa gaaggtgtta cctccgtcac aggaattacc ggtggtgatg caaaaaaatt
    23341 agatgattat ttaaatgagg cagacttttt aagtggagaa acaatcttaa aagctgtacg
    23401 caatgctgta gctgttaatg aagtcaatgc aaaaatgggg ttgatttgtg ctacaccgac
    23461 tgccggaagc gcgggtgttg ttcctggtgt gctgatggct gtccgagatc ggcttgattt
    23521 gacacatgaa cagcaattgg aattcttatt taccgctggc gctttcgggt tagtcatcgc
    23581 aaacaacgct tctatcagtg gtgcagaagg gggatgtcaa gcagaagttg gttctgcaag
    23641 tgcaatggca gcagcagctt tggtttgtgc aaaaaatggg actcctcatc aagcagcaca
    23701 agcagtagcc attacattga aaaatatgat gggactgatt tgcgatcccg ttgcaggctt
    23761 agttgaagtc ccgtgtgtca aacgtaatgc tttaggctct tctcaagctt ttatctctgc
    23821 tgatatggca ttagcgggta tcgaaagtgt cattccgccg gatgaagtcg ttgctgcaat
    23881 gtaccaagtc ggacgtcaaa tgccgtcgat tttcaaagaa acagcagaag gtggcttagc
    23941 tgttacgcca actgctaaac gacttgcgga agagatttta aataagaggg cgtgataaag
    24001 ctccttaatt tcgagtatta agagattagt tatcttcata acaaaaaacg aagagaggac
    24061 taattgccct tctcttcgtt ttttattaat ccatcaattt cgtatttttt acttcatcga
    24121 tcgtttttgt tcctgcaagt tgcatcgtga tcgacaattc tttgttcagg tgttcaaaaa
    24181 cagatgttac tccttctgcc ccacctagat tcaacccata aatcactggt cggccaatcg
    24241 caactaagtc agcaccactt gccagagctt tgaagacatg ctctcctcga cggacaccag
    24301 agtcgaaaat cactggtaca cgtttgttga ctacttcggc aatttttggc aatacttcaa
    24361 aggacgcagg acctccatct agttgacgtc caccatgatt ggatacccag ataccatctg
    24421 cccctgcaga gatagcgatt actgcatctt ctggcgattg tattcctttt acgataactg
    24481 gaagatgggt gatttctttg attgttttga tgtcatctgg tgtcaagcct tgttttgcag
    24541 ctgcataaat ttctgcgatt ccttttcctt cgccattacc acttgcactt tgttcgctat
    24601 acgcagctaa gttaggcatt ggtaatggaa attggaattg attgatgacg tcttcttcac
    24661 ggtaaccacc gagcgttgaa tctgccgtta aaatgatagc tttagcccct gcttctactg
    24721 ctttgttcaa aatgaactca ttgaatctgt cgtctttact catatataat tggaaaaact
    24781 gcggtgcgcc tggcgctgca tcggctgcgt ctttgattgt cgtatttgca taagtgctga
    24841 tggaaaagat tgatccagca gcagctactc ctttagctgt atcagcttcc cctttttcat
    24901 gtgccaatcc ttgggccgct gatggcgctt ggataatcgg tgtatctaat tcaattccga
    24961 aaacagatgt atgcaaatcg gctgagtcga ttccgcgtaa tatccgtggc atgattttct
    25021 ttgtattaaa agaagtcgta ttttctttca tcgtccactc atcttcagaa ccaccgcgaa
    25081 tatagccaaa agctcctgct tccatgcgct cttttacacg accttctagt taggcaatgt
    25141 ttacaatatc gattggatgt tcttcattac ttgtatgata agtcatagta gatccttctt
    25201 tcatcttctt gattacatat aaatcatact aaacttacaa aaagtaagca aacatttact
    25261 ctcagatact tttatcgcta ttctttccaa ataaatcgac ttacaagctg atctacttct
    25321 tggttttcat gaagcatact atgagaggca ttttcacctg tcactacttt ttcctctatt
    25381 tcatttccgc gttgcttcaa caacgcatag accgctaatg cactgtttaa cggtactgtt
    25441 ccatcactca agtctgtttc atctagttga ccagcaatca agaaaaatcg agtggttata
    25501 ggaatattac cgatcatttg ctggtaatct tgatagcggt tagaaacgac agcaggcccc
    25561 tttgctaact catctgtcag agactgcgca ctatcatcga caaaatcatt aaaaggcgcg
    25621 ccaattgctg ttaatgtctg aacttgtggc aatgacgtat cctgtccata cgttcctaaa
    25681 tagcgtagtg cactaactcc tcccatggaa tgccccacta tgttgacttt atctatgccg
    25741 tagttttctt tcagatacaa aagacaagtt ttgatccatt ctgcttgatt ccactcgtta
    25801 tttttattat cttcaaacaa tacttggacc atcggattgt ctgcttttcc agacaaatct
    25861 cctgttgctt gtatttgtcc atctgttcct actgttaaaa ccaattcttt tactgcttgc
    25921 tgattttttt ccaaacgccg caacatccct ttaaaggaat tttctgtccc gctgtagccg
    25981 tggaaaaaaa gtgttggaat agtggttttt tctatcactt tactggattc tgccgttttt
    26041 tctttatcag aaacttcagt agtatttatc ttcgtcgtct ggcaaccact taacgcaaac
    26101 aaactgataa ggactaaagc tgctgcagtt gcacgtttgc ataaattttt gattggttct
    26161 gtcatacacc tcttcctttc catatagaaa aaagaaagac ttgaaaggcc aatcatatga
    26221 tcgacatttc aagtctcttt attaatcgat tttatctact tgatcgaaat caagttctgt
    26281 actggtttca cgtccaaaca tatcgatgtt gactttcaat ttttcttttt ctccgtcaac
    26341 ttctgttact tgtccttcta atccagcaaa tgcgccttcg atgattttca cgacttcgcc
    26401 aacttctact tctagatcat tttgtcgcag gctcataccg atagaacgca agatatgatt
    26461 gacttcttct ggaagtaatg gtgctggttt gcttccggct ccgtgtgaac caacgaatcc
    26521 tgtcacacca ggtgtgttgc ggacaacata ccatgaagcg tctgtcatga tcatttcaac
    26581 aagtacgtat cctgggaatg ttttatgaac gatttctttt tctttcccat ttttgacttc
    26641 agtttctttt tcttcaggaa caacgacacg gaaaataaag tcggccattt tcatactttg
    26701 cgcacgagat tcgatatttg cttttacttt gttttcatat cctgaatatg tatgcaagac
    26761 ataccagttt ttttcaaaag attccattga aggctcctca tttcattgta aaataaaaaa
    26821 acctcagtac acccgaagtt tttctttcgc ttcattatag cactaaaagt acgttgtggc
    26881 tagcgagtta ttttaaaatc cagccaaata agctttggat ggctgtatcc attacgtaaa
    26941 acatcaatcc gaaaataata gaagtttcga tgactactaa cgtatcttta cggagttgtt
    27001 ttctgcttgg ccaagttact tgtttgattt catcttttac gctttttaga aatttcatga
    27061 gacaacctcc cttgctactg tttatttcgt ttctttatgt aatgtatatt gattacaata
    27121 tttacaaaac ttattgattt ccaaacgttc gccgcttttt ccttcactga ctgattttgt
    27181 gtagttgcga gacccacaaa cggaacaagc gagtgctgct tttttctttg ccatttactt
    27241 ctgccccctt gctgagaatc agacttatac ttcataacag tatcacgtaa ctttttactt
    27301 gtcaatttgt gaaataaact atctattgtt ttggataaaa ttatgatatg attaatttga
    27361 aattaagcta aaatgagaca attggaggta tagcgatgct attaaaaaca cttgtatata
    27421 agaaaaaaga tctgacaacc gttacagaga ctagtacatt agaagaagca ttaaaaattt
    27481 tagaaacttc cggataccgt tgtgtgccga tcttagattc ttcaggtaat attttccgtg
    27541 gaaacattta caaaatgcat atctatcgtc ataaagcaaa tggcggtgat atgacgcttc
    27601 ctgtcactca tcttttgaaa aacgctacaa agttcattta cctggatact tctttcttca
    27661 aagtattctt tacgatcaaa gagcttcctt atattgctgt ccttgacagt gaaaatcatt
    27721 tttatggtat tttgacacat agtacgttgc ttaatatgct ctctcaatct tggagcgtag
    27781 aacaaggaag ctatgtactg acaattgctt ccacaggaaa gcaaggagat ttggctgcta
    27841 ttgcaaaaat catttcaaaa cacagcagca ttgccagctg tattactctt gatatcgaaa
    27901 aagacgaata cattcgacgt acattgatca cgctaccggc taacactgaa gcgaaagtat
    27961 gtgaaacgat cgtcaaccac ttagagaaaa agaattataa agtggtagaa attgaaaatt
    28021 tgcaaaacca agaagcataa tcaaaaagcg aaaaaagaaa acagctaatc tgctttcttt
    28081 tttcgctttt tataattaga cacgcttttc aaaatcaagc gcgcgatcta aataatacat
    28141 caatggtgct gaaacagcca tgacgataaa ctcacttaat gcaagcgtgc cataggttgt
    28201 ccaaaatgct tggccacctg ttggaactaa catataagca atcagtccca tgctgatggt
    28261 aaagaagatc gtgttcaata ctaaacgcat ctttacattt ttcactttgt tttgcaataa
    28321 agctgtcagg cctaaagaaa gcaatgtttg gccgccacca aaaaccacat ccatgatacc
    28381 aaaaccaaag aaggcattat agacgatgac cccgcctaaa actccccaaa gcaatttacg
    28441 gttaaagaca actaaatgat tcaaactttc tgaaatacga aactggatcg gccctgagga
    28501 tacaggcgca actaaaatag ttaacgctag ataaagagcc atgatgatgc catttacaac
    28561 gattacggat aaccgttgtc tgcttttcgt tttttgcatt ttctctcctc ttttctccta
    28621 gtttttttaa cgcgggatgg ttgatgaacc gcggttatgt gaaacaaaca ataattataa
    28681 cagacttttc atttatttca atccgtctta tctgctttta aaaaagcaaa agcttaaaca
    28741 atgtaaacgt ttgctaaaaa tcgtgggata tggtataaag taagtgtaag gggtcataag
    28801 aattcccagt aaagcagacg aagtaggatc tgcaagaaca gaattgttgt gaaacttaaa
    28861 taaataaaaa aggatgtggg aatttgagca acctcttact agagaacggt ctagcaagca
    28921 gctgaagatc taagtggaca tgccgaacct tggaacttct ccttacgtaa gtaatggatc
    28981 atgcgcttgc taggcttttt tgtgtttttc ggtcttcgga cctttttcat tttcctagac
    29041 ttctgctata ataaccaaga attaattttg taacagattt ttttgaaaaa acaagtttct
    29101 ttcattcaaa aaatagaaaa agcttgctaa ttattggtta accagcaaac aggagtatta
    29161 aaatatcttg ttttattgaa tagcaggagg aaatcatgaa attccattat catatattga
    29221 tcaatccatc ggcaggcagc ggaaatggct ataaagtagc agaaagaatt ttaccggtat
    29281 taaaaaataa gcatattgac tatacacttc attatagtga atacaaagga cacgatgctg
    29341 agattgctga aactttggca aaagaaacat tgattccttg gatagaagaa gaacagaaaa
    29401 caatcgatac tttccccctt ttgatcatcg taggaggtga cggcacctta catcaggtac
    29461 ttgatacttt ctatcagatg gaagtagaat tcccagttgc ttatattcca gcaggttctg
    29521 gagatgattt tgctcgaggg gcaggccttc caaaaaatcc caaaaaagga cttcagctga
    29581 ttttagcagc tcaatcacca gaaaaagtcc acataatggc ttatgaagaa aaaataagtg
    29641 aaaaaaaagg aatagctgtt aataatttcg gtataggatt agatgcagct atcgtccatg
    29701 cgacaaatca ttcttccaca aaaaagcgat tgaacaaata caacttagga tcattttcgt
    29761 atttattctc tattctccgt gctttattca ctcaaaaagg atttccaatt ctggtagatg
    29821 caggaggaaa acaattaagt ttttcaaacg catttttatg tacagcaacg aagcatcctt
    29881 tttttggcgg aggaatcgcg attgttccaa ctgctgatgc gtctaaacca gtcattgatt
    29941 ttgtcgtggt cgaacgaatc aatttcttta aaatcttgtg gctcattctt ttacttatac
    30001 agaaaaaaca attgaaatcg aaatatttcc atcactacac aacaaacaga ttacgtatcg
    30061 tttcaacaac accgcaacat ggtcaagaag atggagaaga aatggaaaaa cgaccttttg
    30121 atatcacaat aaccacaact aaacagttgt tttggtgtta ataaaagagg ttttgtcaga
    30181 agctacatct ggaacaccgt ttattcggaa aaaaggactg tgacacgact tttgtcacag
    30241 tccttttttt actatgcagt taattctttg cccaattggg ttgccatcga tagtttcttt
    30301 ctttacccaa aataaattgg atcattgaaa acaccgcagc aaaagcaact aagacacaac
    30361 cattgaacca aaaagattct gcaaatgttt gattgtaact gagtgtttca ctgatcaagt
    30421 tattattttg aacaaaccaa tatgttggtg tgaatgccgc tattttgcta accatttctg
    30481 gcaagtattc tgctggtaca aacaccccac cgataaagca actgcctgtg ataaaaatat
    30541 ctttgatccc accgctggtt tctgagtttt ttaccaatga agtgatacaa gccgaaaagc
    30601 taatgatcgg caataaaaac aagaaagtat ttaaaatatg ataccatacc gttatatccc
    30661 acgaggtgtg gatcactaac agaaccatta gaagtaagaa gccactgaac aacagcagcg
    30721 agtaactaat caaactaaag gttactttgc gattcaagtt tcgtttggta atgggcgcac
    30781 tctggtttcg tttactgatc tctttgcgat taaatgctag attgatgacg ctgaaaccgc
    30841 taaaaatgga tagaaacaac ccataagaca agaaattaaa ggttgtgccc gtcaacagct
    30901 ttttcatccg ctgactatat cccgcactta gctcaacttc tccagtaacc gagagtgcca
    30961 tttgtgtctg ttccatagct gcatcgattg ttttatcttc ttcttgaaac agaatcagtg
    31021 tttgcaaaaa ggtgttcact tgctgtgtaa caactgtttt agaaaaggca tctgggcgac
    31081 tctgtatctt gatcgtcggc atctttccta cttcgacttg ttcggtaaag tctgcaggca
    31141 gatgtaagat aatgtttaca cgattaaaat aaagagcatc atcgatttct ttttgtgagg
    31201 ttccatccaa tgtaacgact gtttccttgt cattcaaata tttacgaagg ccatcgacta
    31261 caggcgactc ttcttcacta atcaaggcga ttttcgcatc ttgcagagag gtattttcaa
    31321 catcaatatt ttgcgcaaaa aagaatgtgg caacaacagt gataattaca cctatcagta
    31381 aattcgattt atttgcttta agcaatgtcc aaatcgtttt ataaagcgtc ataacgcacc
    31441 cctctttcca tccaagcatt tcctaacgca aaaaggaaaa taaatccgat caaccataga
    31501 agattggtat aaaaactagc caaatcagtg tagaaataaa gttt
//
LOCUS       DAFTHM010000024        30494 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFTHM010000024 DAFTHM010000000
VERSION     DAFTHM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.024"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            272..970
                     /locus_tag="L7C88_001099"
     CDS             272..970
                     /locus_tag="L7C88_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBP9557944.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(1138..3777)
                     /locus_tag="L7C88_001100"
     CDS             complement(1138..3777)
                     /locus_tag="L7C88_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBP9557945.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(4396..5427)
                     /gene="queA"
                     /locus_tag="L7C88_001101"
     CDS             complement(4396..5427)
                     /gene="queA"
                     /locus_tag="L7C88_001101"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBP9557946.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            5620..6795
                     /locus_tag="L7C88_001102"
     CDS             5620..6795
                     /locus_tag="L7C88_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBP9557947.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            6799..7440
                     /locus_tag="L7C88_001103"
     CDS             6799..7440
                     /locus_tag="L7C88_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557948.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            7437..8354
                     /locus_tag="L7C88_001104"
     CDS             7437..8354
                     /locus_tag="L7C88_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBP9557949.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            8351..9022
                     /locus_tag="L7C88_001105"
     CDS             8351..9022
                     /locus_tag="L7C88_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9557950.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(9563..10051)
                     /locus_tag="L7C88_001106"
     CDS             complement(9563..10051)
                     /locus_tag="L7C88_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBP9557951.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(10252..10518)
                     /locus_tag="L7C88_001107"
     CDS             complement(10252..10518)
                     /locus_tag="L7C88_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBP9557952.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(10518..10781)
                     /locus_tag="L7C88_001108"
     CDS             complement(10518..10781)
                     /locus_tag="L7C88_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBP9557953.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            11257..11442
                     /locus_tag="L7C88_001109"
     CDS             11257..11442
                     /locus_tag="L7C88_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBP9557954.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(11584..13407)
                     /locus_tag="L7C88_001110"
     CDS             complement(11584..13407)
                     /locus_tag="L7C88_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBP9557955.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(14005..16710)
                     /locus_tag="L7C88_001111"
     CDS             complement(14005..16710)
                     /locus_tag="L7C88_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBP9557956.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(17016..17963)
                     /locus_tag="L7C88_001112"
     CDS             complement(17016..17963)
                     /locus_tag="L7C88_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBP9557957.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            18153..18422
                     /gene="rpsN"
                     /locus_tag="L7C88_001113"
     CDS             18153..18422
                     /gene="rpsN"
                     /locus_tag="L7C88_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBP9557958.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(18598..18960)
                     /locus_tag="L7C88_001114"
     CDS             complement(18598..18960)
                     /locus_tag="L7C88_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBP9557959.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(18971..20092)
                     /locus_tag="L7C88_001115"
     CDS             complement(18971..20092)
                     /locus_tag="L7C88_001115"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBP9557960.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(20108..20458)
                     /locus_tag="L7C88_001116"
     CDS             complement(20108..20458)
                     /locus_tag="L7C88_001116"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBP9557961.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(20588..22099)
                     /locus_tag="L7C88_001117"
     CDS             complement(20588..22099)
                     /locus_tag="L7C88_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBP9557962.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(22421..23773)
                     /locus_tag="L7C88_001118"
     CDS             complement(22421..23773)
                     /locus_tag="L7C88_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBP9557963.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(23926..25002)
                     /locus_tag="L7C88_001119"
     CDS             complement(23926..25002)
                     /locus_tag="L7C88_001119"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBP9557964.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            25198..26943
                     /locus_tag="L7C88_001120"
     CDS             25198..26943
                     /locus_tag="L7C88_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBP9557965.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(27223..27660)
                     /locus_tag="L7C88_001121"
     CDS             complement(27223..27660)
                     /locus_tag="L7C88_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBP9557966.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(27644..29017)
                     /locus_tag="L7C88_001122"
     CDS             complement(27644..29017)
                     /locus_tag="L7C88_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9557967.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(29339..29827)
                     /locus_tag="L7C88_001123"
     CDS             complement(29339..29827)
                     /locus_tag="L7C88_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9557968.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(29849..30451)
                     /locus_tag="L7C88_001124"
     CDS             complement(29849..30451)
                     /locus_tag="L7C88_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBP9557969.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         8742 a         6508 c         5651 g         9593 t
ORIGIN      
        1 gccagtatgt ttttctttct tgattaaacg atagcgaatg gcaggttgcg tcattcattt
       61 ccctactttc tatataaaat atcttgacaa ctcccaccat cataatcgtt tcaagtgctt
      121 tttgcaagtt ccctcggctt ccttctactt tatttaatat tctttttttt atcctttttt
      181 tatgaataac aaaaaaaaga aaaacattat gacagaaata ttttttgata catggtatat
      241 tggtgttatt aaagaaaagg agggaaaaat catgcaatct tctgcagaat taaaacgcca
      301 agcaaaagag agtctaaaag gacgttgggg acaagctgtt ttactaaatc taatccctac
      361 attgattggt attgctacta ttcttcttat tatgattcct attatcttgt ttgccaccac
      421 catatatgat ggatcagcga gcgtctcaga agcgacaact tcaggaggcg gtagttcagg
      481 aggcggtggc ggaattattt ccagcatcat tagcgctttg ttcatgagcg gtatttcttg
      541 gacttatctt gatattttac gtggacaaaa agatcagatc gaaccattca aagatgcatt
      601 tcgtggattc aaaggtttgt ttatcggcgg agtgatcagc ttagctgtgc tgatctcgat
      661 ctttacaaca ttatggggtt tgctattagt tattcctgga atcattaaaa gctattctta
      721 ttctcaaagc tattttattt actacgatat cgtccaagaa acaggacaaa cacctaaagt
      781 actggatacg atcactgcaa gtcgaaaatt gatggatggt tataaaggac aacttttctg
      841 gttagatctt tcatttatcg gctggcatat cttagcatta gcaactgctg gtattggtta
      901 tctatggctc agcccataca tttctgcaac aaaagcagca ttttatgaac aattgccaaa
      961 agatatttaa aagagagtgt gacttgtgac cgagggggtg gcaggagaac accgtttatc
     1021 gagaggcagt aaaagaaaca ttcagcccat tagcaaaaag gaggtgtgac aacattcatg
     1081 tcacacctcc tttttgtata gttccagtaa aaagaaaatc aacttagaaa cagttaatca
     1141 ttcctcttct tctgcttccg gtaatcgatg gaacttgatc agttcattca ccgcgattgg
     1201 tacgatagat aaaatcccta ccaagaacca gtgattcaaa ctgatgtgta ctaggccgaa
     1261 tagttcttgc gtaaatggca gcaaagcaac agccgttgta atagctaatg ccagtaacgc
     1321 catttctacc aaagctttat tggtcgctaa attgactttg aagatcgatt ggctgctgcg
     1381 tacattgaac acatgcagaa tcgatgaata agctaagatc aagaatgcaa cagtttgacc
     1441 gacatgctga cttgcgtcta cccatgggct gatagtatcg acataactac ctaaataata
     1501 accaaacaag gttacgatgg tgaagacccc tgcatttatg gcaatttttt gcaataaacc
     1561 tcgagcaaag atcccttcat ttttcggaat gggtggctga tccatgatgc cgtgttccgc
     1621 tggctctctt cctaaagcaa atcctggaag tccatcagca actacattga caaacagtag
     1681 ttgcacagct gtaaatggtg ctccccatcc taacagcatc gcaatcaaaa caataaagat
     1741 ctccgaaata ttacagctta gcaaaaagtt gatagcttta cgaatattct gataaaccga
     1801 acgtccttga ctgacagcgt ctacgatcgt cgcaaagttg tcatccgtca aaatcatatc
     1861 tgcggcactt tgcgccacat ctgttcctgt gatccccatg gcacacccaa cgttacttgc
     1921 tttcaacgct ggtgcatcat tcacaccatc cccagtcatc gctacgactg cacccgtacg
     1981 ttgccaagat ttgacgatcc ggatcttgtc ttctggcgtt acccgagcat agacagagag
     2041 agctttgaca cgcgcatcta attcttcgtc tgataattga tgcagttctg atcctgaaag
     2101 tgcttctgac ggatcattca agatacctaa ttctttcgct atggcactgg cagtcaccac
     2161 atgatctcca gtgatcatga ctgttttgat gccagccttt ttcgctcgct tgattgctcc
     2221 tttactttct ggacgtggtg gatcgatcat tccgatcaga ccaatcaaac gtaagtcttt
     2281 ttccagtgct tcagaagaaa tatcttgcgg ttcttcgtca taagtagcat aaccaacagc
     2341 aatcactctc agtgcccgtt taccaaagcg atcattaacg atcgccgctt gttctacatc
     2401 gcctgaacta aagcgcggag caagaacatc gaatgctcct ttggtgattg agatgtattt
     2461 ttcgcccatt tggtgaactg ttgtcatcat ttttcgttca gaatcaaaag gaagctcgtt
     2521 tactcgtgga tatttttctt ctaattctgc ctttgtatga taattctctt caacagccct
     2581 tacgatggct acttctgttg gattaccttt gataacaagg tcgtcatctt cttgctcgac
     2641 cgtcacatct gtacatagtg cagccatttt caatatttcc atcgcgctgt tcgtcattga
     2701 atcttcgata ttcgttactt catcttcttt gctccatacc cggcggacgc gcatttcatt
     2761 ttgtgtcagc gttcctgttt tgtctgagca gataacatta gcggttccta gcgtttcaac
     2821 tgctggcaac tgtcggatga tcgcatgttt cctcgccatc ttctgcacac cgtatgcaag
     2881 tgtcaacgta acaataacag tcaaggtttc cggtacagct gcaacagcca aggaaatcga
     2941 agtcatgaac atctcaagga gtggttctcc ttgcagttca ccaatcacaa atactaaagc
     3001 cgcagccgct aaagcgatca tactgattcg tttgcctagc tgattcaatc ggacctgtaa
     3061 aggtgttttt tgcatagtat tttcgttcaa aagatccgcg atcttaccca tttctgtagc
     3121 catgccaatg gcagtgacga tcgctttccc acgacctgca gcaaccgtac atcctttaaa
     3181 taccatatta agttggtcac ctaatgactc atcttcttca gcaataaatg ctgcatcttt
     3241 ttcaactgct tcactttctc cagtcaacgc cgattcttct acacgtaatt gtgatgcttc
     3301 gatcaaacgg gcatcggcag aaatagcatc accggactct aaaacaagaa tatcacccac
     3361 taccagttgc tctgactcaa cagtggtcac tttgccgtct cgtatgacag ttgccgtttg
     3421 tttattcata tcttgcaagg attccagtgc tttttctgcg tttccttctt ggacaatcgc
     3481 caataccgag ttgatcacaa cgatagcgat gatcagcagt ccttcaaata aatccccatg
     3541 ttctgtagca aatgcggtat aaaaggaaat caccgctgct acaagaagga tgatcgttgt
     3601 aaaatcggac aagcttcgaa agaatttttt gatcatcgat tctttcggcg cctcatcgaa
     3661 tttattcaat ccctgctttt ttcgccgttc atccacttct tgtgaagaca acccagtatc
     3721 tggatctgct tctgttacct tctttacttc ttctattgtc tgcttgtatt cttccatcct
     3781 attcctcctt taaaatcttc gtacaaaaaa aggtacttat tttactataa catccttttt
     3841 ttatttactt caaataaagg gcttatcgat tatttgttaa gaaagcgtaa aatttaaagt
     3901 gcttatattt gcaaacgcta ccaaaggatg ctattatata gatgtaagga aggaggatac
     3961 catcaaatag acagaagaat ttctcgatag aacagtgtaa gcaaacaaag ttgttagaag
     4021 tacaggtttc acccagacat gcgtgtagag tacaaaccta taaatagtga atgcgtatgg
     4081 atgtttggat cacgaagtat ccgaaacaag aagtaatgcg atacgtaaca attgaataac
     4141 gtaaacgtct gaaaattgaa taggaacaag agatgtttca aatgttgaag atgtaacgaa
     4201 aacaaaattt ttgtttaaca tgaagaaatt caacaccgtg ctttgcatgt atgatggaaa
     4261 gttacaatca tttctgttta tttgaatcct tccgaggtac aagaaagccg agcttatcga
     4321 gagctcggct ttttctttgt cataaaatct ttgtaaagct tttttgttat tcaaaactag
     4381 cggcttttca taaccttatt tcacgaacat cgcatctcca aaactaaaga aacgatagcg
     4441 ctcttcaatc gcatgctggt aagcagataa agtcaattct cttcctgcaa aggcactaac
     4501 taacatgact aaagtcgatt ttggcaaatg gaaattagtt gagaaagctt ctaccacttt
     4561 gaattcatag ccaggcgtaa tgaaaatatc agtccatccg ctgtctgctt tgatttctcc
     4621 attaaatttc gttccaatcg tttctaatgt tcgaattgaa gttgttccga cagccacgat
     4681 tttcccgcca tttttacgta cttggttcaa tcgctcagcc gcttcttccg tcaaacggta
     4741 gaattcacta tgcatatggt gttcttcaat tttatctacg ctgacaggtc ggaatgtacc
     4801 taaccctaca tgtagtgtca gatagactaa ttcaacaccc tttgcttcga tctcatcaag
     4861 taattctttc gtaaaatgca atccagctgt tggcgctgca gcagaaccat tttctttcgc
     4921 atagacagtt tgatagcgat ctgggtcttc cagacgttct ttgatatatg gaggcaatgg
     4981 catttctccc aatgattcaa gaatctctag aaaaattcct tcatactcaa agtcaatgat
     5041 ccgtccgccg tgttccaatt cttctttcac tactgcttgc aatctgccat caccaaaaga
     5101 gattcttgtc ccaactttgg cacgtttcgc aggtttgatc aatgtctccc acgtatctcc
     5161 ttgtgtattc gttagaagaa ggacttctaa atgcgcacca gtatctggtt tttctccata
     5221 taaacgagca ggcagaactc gtgtattatt cataactagc gcatcaccag gctgtaactc
     5281 ttcaatgatt tcatggaaat gtttatcttc catctctcca gttttccgat ccaaaacaag
     5341 taaacgagaa tgatcgcggt cttttaatgg tgtttgtgcg attaattctt ccggcaagtc
     5401 aaaatcaaaa tcttctgttg ttaacatatc gtcactcact ttctatcatg tgcttcatca
     5461 ttctatcatg tttttcgttc tgttggcaaa atcagcactt tttcacttct attttttgtt
     5521 ttcctaaata aaaaaactac cctatttgta ttttttcatt gttttaggca tactagtaat
     5581 agatagttct tcattgaaaa tagaaaaaga ggtggcacca tgattgaatt tcaaaatgtg
     5641 tcaaaaattt ataaaggtgg aaaagtcgct gtagaggacg tcaatctttc atttgaaaag
     5701 ggtgagttca tttgttttat cggtacgagc ggaagcggaa aaacgacgac gatgcggatg
     5761 atcaaccgaa tgactgatcc aacacaaggg aaaattttga ttgatggaaa atccatccaa
     5821 gaaattgatc cagtggaatt gcgacgtcag atcggctatg ttatccaaag tattggattg
     5881 atgcctcaca tgacgatccg tgaaaatatc actcttgtcc aaaaattgtt gaaagtcagt
     5941 caagaagaac ggaataaaac agctgaaaaa atgattgatc ttgtggaatt gccccgtgag
     6001 atgttagatc gctacccaca tgaattatct ggtggtcagc agcagcgtat tggagtcgtt
     6061 cgtgcccttg cagcgaatca agatatcatc ttgatggacg agccattcgg tgcgcttgat
     6121 ccaatcactc gtgattcctt gcaagacctt gtcaaagatt tacaagagcg tttgggaaaa
     6181 acgatcgtat ttgtaaccca tgacatggat gaagcgatta aactagcaag ccgtatcgcc
     6241 atcatgagtg aaggccgtgt gatccaattt gatacaccag aaaatatttt acgtcatcct
     6301 gcaaacgatt tcgtagaaga gttgattgga gaagatcgcc tactacaagc caagccaaat
     6361 gcgacaagag tcggcgaagt tatgctaaat acagcaatca cgattacacc ggaaaaatca
     6421 ttacaagaag caatcaaact gatgagggaa aaacgtgtag atacgttgtt agttaccgat
     6481 aattcgaatg tattaaaagg atttatcgat gtagaaacgt tgaataaaaa acgaggaaaa
     6541 gtatccagtg tcggcgacat tttgaataaa catgtttttt acgtaaaaga atccgcctat
     6601 cttcgtgata ccttgcaacg cattttaaaa cgcgggctga aatacgtgcc ggtcgttgat
     6661 gaacagaaca aagtcgtagg tatcctgact cgtgcatcat tagtggatat cgtctacgat
     6721 gtgatttggg gagaagatcc cgcaactact gatgttgcag agtcagctac tcctgaagaa
     6781 tctaaggagg tctgacctat gcagcagttt tttcatcagc acggttcaga aattctctca
     6841 aaaggttttg aacatcttta tatttcagga cttgctttga tcattggtat catcattgct
     6901 gtaccgcttg gtgtcttact gacacgtttt ccaaaagctg ccacgattgt gattggctta
     6961 accagtgcct tgcagacaat cccttctctt gctttattgg cattgatgat cccgctattt
     7021 ggcgtaggta aattacctgc gattatcgca ctctttattt attcattatt gccgatttta
     7081 cgtaatacgt acattgggat gaaaaatgtc gattggaatt atcgggatgt ggcaaaaggc
     7141 atggggatga ctgagttcca atccattttt tccgttgaat tgcccattgc tatgccaacg
     7201 atcatggctg gtattcgttt agctgccgtt tacgtgattg catgggctac acttgcctct
     7261 tatatcggcg ctggtggttt aggcgatttg atttttagtg gactgaataa ttaccaacca
     7321 gatctcattt tggcaggtac gatccctgta acaattttag cactattggc tgattggctt
     7381 ctaggtctct tggaacaccg gctgacaccg atcgcactta gagaggagaa tgaagaatga
     7441 aacgtatact aaaaatgacc atggttcttt tctctcttct tatacttgcg agttgttcct
     7501 tccctggtct tgccagcaat acagatgaag acaccatttc gatcacaggt ggaatcactt
     7561 cagaagcaca gatcttagca agtctagttg ccggaatggt tgaacattat acagataaaa
     7621 ataccgcaat catcaacaat ctggctacta caactatcaa ccatcaagcg atgatgaacg
     7681 gagatgcttc aatttcagcg gctcgctaca caggaacaga tttaacgact acattgaacc
     7741 ttcctcctga aaaagatccg aaaaaagcgt ttgctaccgt gaaagatgaa tttgagaaaa
     7801 gatacggtca aacgtggttc ccgtcctata gttttgaaaa tacgtatgtc tttcttgttc
     7861 gaaaagacac cgcacaaaaa taccatctat ctaaagtcag cgatctgaaa aatgtagcgg
     7921 atgaattagt agctggtgta gatacttctt ggatcaatcg taaaggagac ggttatgacg
     7981 gcttccaaga aacttatggc ttctccttca attcgatatt acctatgcag attggacttg
     8041 tttatgacgc agtcgaagca ggaaaaatgg atattgttct tggctactct acggatggac
     8101 ggatcgccag ttatgatcta gtcatgttgg aagatgatcg tcaattcttc ccaccatatg
     8161 atgctgctcc agttgtagac aacaagatat tagctgatac gcctcattta aaagaagcct
     8221 taaataagtt aggtcatacc atcagtacgg aaaaaatgca ggaattgaac tacgaagcag
     8281 ataataatct agtggaacca tcagtagtag cacaacgttt cttacaagaa aaccactatt
     8341 ttgaagggaa gtgaagcaat tggataaaat gaatgtcttt caacaatttt tctattattt
     8401 ccaggaaaat ggctcctata tctttgcaca atttatccgt cacttcctga tttctatcta
     8461 tggtgtcctc tttgcagcag ttgtcgggat tccggttggg atcatgattt ctaggagacg
     8521 taaattagca aactgggtga ttcgtttggc gaatatcatc cagacgatcc cttctctagc
     8581 catgatctcc attttaatca ttggattagg cctgggagtc aatgtcgtga ttgttactgt
     8641 atttttgtat tccctcttac cgatcatcaa gaatacgtat accgggatga tccaagtaga
     8701 caaaaacatc cttgatgtcg gcaaaggcat ggggatgact gctagacaac gactattcat
     8761 ggtagagtta ccactctctg tttctgttat catggcaggc ataagaaacg cgttagttgt
     8821 tgccatcggg ataaccgcga tcggtgcatt cgtcggtgct ggtggtcttg gagatatcat
     8881 tatccgagga accaatgcaa cagagggcac atcgattatt ttagcaggtg cattgccaac
     8941 tgcattaatg gcgatcatca cggactggct tttaggtatt ttggaaagac ggctagatcc
     9001 agccagccgt acatcacgct gatgttattg taaaaaacaa aagcttctgc gaccatttgt
     9061 tggtcgcaaa ggctttttta gttctgtcat ttttaaggca ataatccact ctgattcttc
     9121 cctccttatg ggtaaagagt tgcttttctt agctatttat ccattccgta tactccaact
     9181 tcatactgcc aacgggttca tatctgcatc caccgactaa gtttttttct tatccgctaa
     9241 ggcattttgc caatccattt tcccatcact cgtcatggaa ttcataccac atgatctcta
     9301 aatactcgtc tgcttgttct ttgaattggg catcaattct tacatccttt ggcgtggctt
     9361 tcatttaagc cttttccatc agtcctcgat tgttcgatgc cttcagctgc atcatcaaaa
     9421 ctggtgactg ccgtatcggt aacttcgatc atcttttata caatcgggaa cttgccatcc
     9481 tcatccttgg ctaaaaacat atctagccat tccagcttct cgccatggga ggtttgcggt
     9541 tcctaaaacc ggtacacgat tcttatggac tgcatccgtc gcaactagac ttggcgatac
     9601 gatgatcctt caccagaaga gcacccccgt aaaccaattg atcgatatat tgccaataag
     9661 aaaagacatt ggcgtaaaag atatcgatcc ctcgtgatgc attgccgttg atactgctat
     9721 tcatggccga aagcgccacg actttaactt cttccgtttg agtgacattc atgttcggca
     9781 atgtcgcttt ggatacccgc tctgctaaag gaacgacact ggtattgtat ttcgtatctg
     9841 tatcttttcc aaaagaccat gccaacgaat cctctgggaa ccaataagac gactccggtt
     9901 gattgtccat tgcttttttc aacatacttt tggctgtttc tcgataaacg acatttccaa
     9961 ttgtcttcgc ctcactttgg cgataatcga tggtcgttgc cactgccaac actaacaacg
    10021 atgctccaat tttactgatt ttccttgtca cacttcttcc tccttgtttt acataaaccc
    10081 gtcaacattc cattcctaaa ctcaaacaat gacccttcaa aggtggagat ataggaacaa
    10141 attaaagaaa tcatgcaata aatccaagaa ggttggtttt agaacaaaaa aagagtctcc
    10201 tttttgggga gactctttgt taactatcta aaaaggttgg ctcttctcac ttcactcata
    10261 atgtgtccag gcagaataaa tttctacaac tttattttcc tcatcaactt tgtaaaccac
    10321 tcgatgctgt ctattcagcc tgcgtgagta tctgccttca tgtgtaggtc tcagcttttc
    10381 aaaagactgc gtgggcatat atggatcttc cttcaatgtc tgaatcactt cttcaaattg
    10441 tttctttaaa ttcgtttgct tgatttttct taaatccact ttcgcagagt ttttgattgc
    10501 gactgtatag ttactcatca aagagcttcc caatcaatat catcgatatt cgtaaagcta
    10561 ctgtcgtctt tttcgcggtc tcgtacttta tctaaagtac ctgtttgctc aagaaaaagg
    10621 gtttcttgaa tcgctctcca gtcttccagc ccaatcaata cagcattgtt tccactacga
    10681 tcactaataa tctcgatttc agtatgattt tcatttacct ctttcaataa ctgataaaaa
    10741 tttttacgag cagtgctagg attcatcgtt gtattagcca ttgtctctcc tcctttttct
    10801 gatataatta tagcgtactt gattaagtac gtcaaaaaaa tacaataaag cacttaaatt
    10861 cagcaaactt ttcctctttt ttacatagag aaaaagaccc ctttttaggg aggatctttg
    10921 tccacgctca cttcttactc ctttacgact agcggtagcc aaacgtaaag taattggtaa
    10981 caacgtatca tctttagcaa aggtcgaatc caaagcctgt gagtctatgc aacaacacca
    11041 atacacgaag gttcctcgtt gcagtgtgac ttgattgata tcttgaataa cctgaggata
    11101 cgcacgaaag atttgtaacg gttattcaaa actgattttg gccgtcaagt cttctactgc
    11161 ctcaaaaatg attgcctctt tcgtctcctg tcattcatgt tcactatcga tttgatactt
    11221 gcttagaccg ttgggtttgt gaatcaccaa ttaaaaatgg cactgagtta tggtaacaaa
    11281 aaatggtcac ttgacgaggc tgagattcct acttatgaag acacatggca cttaagagtc
    11341 gaggtaaagg aagaagctga aaatatagga ggctgtacat tatttggcaa aggattcgga
    11401 aattatgatc aagacatcaa aatcaaaatg ttttacagct aaataggaag aataataaca
    11461 tttcatacgc tgttcccatc tttaatggct tatagagggc acctttagct gagaataaga
    11521 caaaacagac cctctagctt caattaagag ctagagggtc tgtttttgat tttaaaactt
    11581 ggtttatttc ttcaaatggt agctataggt gctgacaacg atattttcac gccaagacaa
    11641 tcgcaatctt aaccgcaaac ttgtttggtt atggagaata ttctgccagc gtctgtttgg
    11701 tacaaattga ggaatcaaca cagtagttgt atagttttgt ttcgctgcat ttttacttac
    11761 gatatctaca taacggataa ttggattttc aatcgagcga taagaagagt ggacgattga
    11821 aaaacggaca tctgggaaat gctttttaaa ttctgcttcg atttcttttt ctttttcgac
    11881 atcttcgtct agcgaaacat gcatcgcaac gacataatca ccgatcgaac gtgcgtaatt
    11941 caacgcaccg atatttaccc gtgtcacatt cccgactaat acaagaacgg tattcccgtc
    12001 ataatcatgt agttttgcat cattttctaa acgaagctgt tctgctactt ttttataatg
    12061 atcatggatc ttataaaaaa tgaacataac gattggcata atgatgaaga aaggccaaat
    12121 gtcccctaac cgatagacaa acaaaatcgc aatgattgca tatgagatga acgcacccgt
    12181 aatattggca atcgatttgc ttaaccatct ttttccttct tttttccatt tgacgaccat
    12241 ccctgtttga gataaagcaa atggaatgaa cacgccgata gagtataacg gaatcaagcg
    12301 ttctgttgag ccatggaaaa taaacagcaa tacgatcgaa cctagcgcta gtgtgataat
    12361 cccattggaa tagcctagtc gatccccacg atcttgatac atgtgaggca tgaatttatc
    12421 ttttgccaga ttgtatgcaa gaactggaaa agcagaaaaa ccggtgttag cagcaactgc
    12481 taaaatcagc gctgtagcaa attgaaggac gtaatacaaa ataccatgtc caaagacagc
    12541 tttaccaatt tgagacaaaa cagtgacttc tttttcagga acgatcccat accaatagtt
    12601 gataaatgtg atccccacga agaagaaacc taagatcaat gccatcatcg tcaatgtagc
    12661 agcggcattt tttgctcttg gcttcttaaa gaatggtaca gcattactaa tcgcctccac
    12721 cccagttaaa gaggaagaac cagaagaaaa tgctcgtaaa atcaaagcga tagaaacacc
    12781 cggcacagcc gctcctggaa gtgcagtagc ttgcaatggc acagcacctg tcacgatatt
    12841 atataaacca acaacgatca gtaacgagat cacaaggata aatgtgtaca ccggaaataa
    12901 taggaacgat gcagattccc tcagcccacg aagattcagc atcatcagta gcaaaacgat
    12961 tgtcacagaa atagcgactt gatgaccgta gagtgctggc accgctgatg tgatcgcttc
    13021 agcacctgct gagacagata ctgctactgt caacatgtag tcgatcaata aagagccacc
    13081 ggaaatcaag ccagcattct ttccaagatt ctcactgctg acgacatatg ctcccccgcc
    13141 atgaggataa gcatggatga tttgacgata tgatagcgtt aatgaaatca ataaaataat
    13201 aacaaaagcg gcaatgggta gcgaatacca gatggctgca gcagacaaag cgactaaaac
    13261 gacaacgatt tgttccgtac catatgcaat agatgataac gcatcagacg acaataatgc
    13321 caaagcagca aatcgggtta atttgtgctc atcattttca gcagatttta aaggcttacc
    13381 tactaacaac ctttttaagt aatccaattt ctaaactcct ttacacacaa ttttacttca
    13441 agttttatag tcgaaaattt atagtaaaca agatgttata gtacgctcac tgaccttaaa
    13501 agtcaataaa ctttaagaaa ataattggaa aaaaacagaa aaatatcaag cgctttttca
    13561 aacgctttaa tacagcaaaa atctaacatt tttttatggg ctttttcttt gaattctata
    13621 ataaaaggat agaacttgac ttagaaaatc aagttctatc ctttttgata tcttaacttt
    13681 tggaagagag atgtaaggct gctttctacc catcattctt actactcgaa gcatagcgca
    13741 gttgtcacaa cctcttgata aacggtgttt aaaagcttgc atctgcggta ataagcccaa
    13801 ccaaattaaa aacataagaa gctgttttta tttggtcgtt cttattactt gatgcagagc
    13861 agctttttta caacctcttg gtacacggtg ttcaatcagc tgaccctcgg tattagctca
    13921 aaaaaacggc aaaatatgag gaactatttt tccatttttt tctctaatac tcaggtcaaa
    13981 acactgattt cacaacctct ttttttaatg aaaaatatgg ctctcatgcg ccgcttcttt
    14041 gaatttcgtc attttttctt cgatgaacgg atagattgcc gttcctacga ttccaaagac
    14101 aacaaacaaa ccgatcatga tccagattgc tttcgtagca tttggccaat aaattcctcc
    14161 tgcagattcc cgtaacaagt ttaccgcatg agtaaatggc aagaacggat tgatcatttg
    14221 gaagaatttc cctgagactt ggatcggata gttcccgcct ccgccagaga tcgacagtac
    14281 taagatgata atagcgatcc ctttaccgac attatcgaat aatgcagcca agacatagac
    14341 gatcatcatg aacgctaagg cgatcaagac agcaaatgac acgctgtaga ccggattttg
    14401 gacatctact cctagtaaga aaatattccc taatgtaacg atcaagcttt gcgcaatcgc
    14461 cattgtcaaa aatgtcagca tacgagcaac gaattgttct cgtttcgtaa aattgtttcg
    14521 gtctttcttt cctaaatagt attctgtcgt agcaacactt gaaagaagaa cagcgccgac
    14581 ccacagacat agtgcagtat aaaacggggt gctagctgaa ccgttatttg cgattggata
    14641 aagcgcattg gtttgtagct caacaggttg tgtaaagaag tcactttctt ttgttgcgtc
    14701 tagtttcaat aatttgatga cttcgcctag atcgacttct tgttcgcctt ttcggatcgc
    14761 gtctgctgct ttttggatac cagctttgat atttggccag tcattgttga tcaagtccgc
    14821 agcagcgttc acagctgttt cgacttctgg cattttttca tttactgttg tcaatgtacc
    14881 ggtgatttca ttttttagtg ctggccaatc attttggata aaatcagcgg ccaatcctaa
    14941 tttttgctga atgatcggta attcattgtt gtataggtct gccccttcat tgatgccatt
    15001 gacgatggta tccatatttc cattcagcat tgtattggca tcatggattt cttgtccaat
    15061 tgcaggcatt tctttttgat atttttctaa aattgccact gcattcgtta cagttgcttt
    15121 cgttgagctg agaagcgaat caaagtcgat ctggtccgct ttgctcagtg cgccttgtgc
    15181 agtcccaatc gtatcgatga cttggtctag tagagaagtg acagtggaac tgatttgacc
    15241 tgtattgata ccagcaatga tgccattgat attattaaca acggcatcaa tttgatctag
    15301 caattcatca atagccttcg tgtcttcatt ttgaacagct gtgttcaaag cagataggcg
    15361 gttttgcaga ttgcttagca agggttttaa ttgatttagc tgatcaataa ttggctgtaa
    15421 tttcgtattt ccagcacttg tttgcaattt agtcaggaac tcgaccagtt tatcgattgc
    15481 attttgttgt tgagatattc cgtcaataaa gccgttcaat acattgctga tgtttttctt
    15541 ttcatcatca gtcagcttac catcttcaat agctgttctt acagtatcta ttaacgaacc
    15601 tgtcgttgtt gccacttgtc caattgactt caatgtaaca tctacactgt ttgtgatgct
    15661 tggtatcgca tctttcagct gagaggcacc tgattttgtt tggtttgcta gatcacttgc
    15721 ctgattttct aaatttttca catctggcaa gatatcttgt acttgttgga tgatcgtcaa
    15781 gccttgtttt gcttcatcga ttccttggtt cattgtctct tggatcgaag caaaatcgcc
    15841 gtcgatctct gctagttgct taccggcatt ttggatctct gggatttttt cttgcaaatc
    15901 aaggatgatt tttgcttgat ctttcaactc aggcattttg tcattcaatg caacgacttt
    15961 ttcacccatc tcatctactt tagggatgta atccacgaat tcatttgctt tattcagttt
    16021 ttccttgatt tcaggtagtt gactttgtaa ttcgaggact tgttttgtgt agccgtcgat
    16081 cgtgtccaaa ttttcatctg ttgataaaat catatcttta actttattga tacttactag
    16141 gttcgtatcg atgtcgtaac ctatctcatt gaatactttc aataaagtcg aactggctgt
    16201 tttgataaat tcatttgtga tttgcgattg gatcgaactt gctcctttat cggtgatttt
    16261 cggtgcaatc gcattgattt tttcatttac cgtatattcg atttttggtt tcttgatatc
    16321 accactagta aaactcagca gatcttctga gaaatccttt ggcaagtaaa tacctgcgta
    16381 atactttccg gaacggactc cgtcttctaa ttgttctttt gaatcaacga attgccatcc
    16441 taattgttta tttttatgaa gcgattcgat gacttgctcc ccaatggcca cttctttacc
    16501 ttgaaactct gctggcttgt ctgcactgta aacagcaatt ggcagctctc cagtatttcc
    16561 atatggatcc cataatgctt tgatgttaaa ccacgcatat agcgaaggga tgatcatgat
    16621 cgcgatgatc agaagtgttg caatcgggtt tttgaaaatc cgtttccagt caagcaaata
    16681 taatcgaagc gtatttttga ttgactgcat agttctcccc cttcttcttt tttcagctga
    16741 attactttac catgtatttc atactttttt caatcggctt ttttcaaaaa agtcgaattt
    16801 ttggacatat cacggcaatt gtctcattgt aatctcttac atattgagaa ataattaagg
    16861 attacagcct ttactttatc atgaaataaa agggaaagat aattttatgc caaagttttt
    16921 atctattata cgtatacgca aaaaagctaa aacatttttt gtctttgccc ctacaaaaat
    16981 gtttcagctt ttttcgtttt ttattcctgt atttcttatt tttcgaatga caggatgatt
    17041 ttcccagcag gaggatgtcc ttcaactagc tgatgtgctt ggatgacatg cttaagtgaa
    17101 gcagacagat tcattgaaat aaaaacatga aaggctcctt tttggtaggc tttgattatg
    17161 ccagcaaagg cttctgcatc tagatattcc tttcttggaa caaacgattc ataaaagcct
    17221 tccttttttt gccgcaaatc tagatctggg aggtcattta atgcaacata cctgccgcct
    17281 ggtttcatga tctggatgcc ggtttctcct ttgatacttc ctttcgtcgc atcgattaca
    17341 aggtctgcct gatcagcaaa ttgcagacct ggatttgttt tatcataagc agcaaatgct
    17401 gaagctccta atttttttac cttttcctca tttttactgg atgcactggt taagattcgg
    17461 attccctttt catggagaag ctggatcaga cttgacccga ccgcacctga tgctcctagt
    17521 atcattacag tatctgtcgg ctggatttcc gtcaaatggt tgattagatt ataagccgta
    17581 attcctggcg tgaccattcc ggctgcttct tcccaactca ttttatctgg aatttttgct
    17641 acttttgctg atggcaacac gacttcttct ccgtaagtcc cgccgactgc atggacagct
    17701 actcgatcac ctacatgaac agttgtgaca tctgaaccaa tctctgtcac aataccagcg
    17761 ccatcattac ctggtacata agggaatttc aatgttcgta tctctttcat ttctcctaaa
    17821 cgcaaggcaa catcataagg attcacactg aatgctttta tttctacacg aacatgtcca
    17881 gaaccgactt ctctgggatg agcatcgatt tcttcaaaaa catcttgtgc ttctccgtaa
    17941 ccgttaattg caaatcttcg catggtcacc atctcccttt ttctttaagt ttacgtttat
    18001 gcctttattt tgacaaaaaa aatgtctttt cgttttggcg catgattcaa aacaaaatag
    18061 ttgtcttttt tcgcgtaacg tgttaaatta tttatctaaa agcgtaaaga ttacgattta
    18121 cgctaataaa aaataattgg aggaatttgt tgatggctaa aaaatcaaag attgccaaag
    18181 caaaaaaaca gcaagaaacg attgaacgct atgctgcttt acgccaggaa ttaaaagcgc
    18241 aaaaagatta cgaaggcttg cgtaaacttc ctttagatgc tcgtccagaa cgattgaaaa
    18301 atcgtgattt aatcgatgga cgccctcgcg gatacatgcg taaattcggg atgtcccgta
    18361 taaaattccg tgaattagca cataaaggtt tgattccagg agtaaaaaaa gccagctggt
    18421 aatccaagtc tggctgtaat gtaaaggagg agggcgcatg gaccactcct tggatcatca
    18481 aaaaagatac gttcgcttct tctagcagaa atgctggtac tagaagcaga cgtatctttt
    18541 tttacgcaca gctggtcctt ttttatatgt aaaggctgca tggttacttc gctatattta
    18601 tttagtaaca ggagtcagtg cttcgatacc cacactaatt ttcaatgctc ggtcaacttc
    18661 tgccataatg ggtcgatcca aatggcagac cttttctttc aatcttgatt tatcgatcgt
    18721 tctgatctgc tccaacagga taacggagtc tctttctatt cctgttccag tagctttgat
    18781 cccaatgtga gtcggaagct taggtttagc catttttgcc gttatggccg caacaatgat
    18841 cgtcgggcta aaatggttac ctagattatt ttgaataacc aaaactgggc gtgttccgcc
    18901 ttgctccgat cccacgactg gagaaagatc agcaaaataa atatctcctc tttttaccat
    18961 aggatcctcc ttattcttga tattctcttg gtatccgctg tcctaatccg caagccactt
    19021 catagtggat cgtacctaat tgatctgcta tatcctgcat agtgatttct ttgtctgcat
    19081 ttttgccgat aagcgtcact tttgttccga caggaaattc ttgaggcaat cggatcatca
    19141 gttgatccat acatacacgc ccaatcgttt cacagtagtt cccttctacc aatagagaaa
    19201 aaccctgcat ctttcgtggc cagccatctg cataaccgat cggtatcgtt ccgatccact
    19261 ctgcttcagg agtgatatat gtttctccat agccgattcc ttcacctgct gggagttttt
    19321 tgacttgaat caattcagaa accagctcaa gtgctggctg caatggataa acttccggta
    19381 gtgcgtgccc agagggatta agtccgtaca ttgctactcc ataacgaatc atattgccga
    19441 ttgtttcatc atgccataaa gccgttgcac tattgctgac atgtacatat cgaggaagtt
    19501 cgggaagttt tttcagcact tctataaagc gttctttttg cagattccaa tatgtatcat
    19561 ctgcctgatc tgctgtagaa aaatgggtaa ataaaccttc ccattctaat acacgacttt
    19621 ctttgatgaa tgcagctgcc tcttttactt cttcaggtgt acaaaatccg atacgaccca
    19681 tcccagtgtc tgcttttaga tgaatcgaaa gaggcgtctc tagcttactt ttctctaaaa
    19741 cagcagctgc tgcttgcaac cattcccgtg tacctgcagt tactgataaa tcatgagcaa
    19801 cagctacagt cagtgcgtcg taaggaacca tattcaagat aaggatgggc tgagtaaatc
    19861 cagcttctct caactcgact ccttcatcta aatttgaaac acaaaagccc gaagctccac
    19921 ctgcaactgc tgcctcagct gtttcaatag ctccatgacc gtatccgttc gcttttacta
    19981 ctgcaaacaa ttcttttcct tgcggaagtc ttgcaacttc atttgctaca ttttcagtta
    20041 tagctttttt atgtatcact gctttcgttg ggcggtgcca agcgacaacc atcgtttttc
    20101 cttctttcta gtcttccaaa ataatttgtg caaaagctgt ttcatttgta tgagtaatac
    20161 tgacccatac attgccttca tgaggtgaac gcgtcacaac aggctgacca ttttcatttt
    20221 ttaaaatctc gacatcttga aaggtaactt ttccgatccc agttccccaa gctttagaga
    20281 aagcctcttt gcaagcgtaa cgcccgccta aaaattctac ttggcgatga aaaggcaagg
    20341 actggaatag tttcatttca tcagaggtca agattcgtgc aatgaatttt ggtttttctt
    20401 cgatcagccg agtgatccta ggaagttcga ctgcatcgat cccaattcct tttatcatat
    20461 gcttttctct tttcaataaa tttagaacac tctcattcta ccaaattata accattttgc
    20521 cacaaataag tccacaaata acaaaaatga aagtttctct taaaaaagag aaactttcat
    20581 tttatgttta atcgttattt gaacggatta caaatccgcg ttttttatca ttgtgacgtt
    20641 taccgccatc tttttggctg ttattatttt tgctataacc gccttttgat ttgtttccac
    20701 gataattacc gccgtcacga cgattacggt tgtttccgcc accacgtttg ccatttttat
    20761 tgtatccttt tttctgcatt ggcaatgggc gttctggtgt gatcttcact ggcactgcat
    20821 cagctggatc ttttgctgtc gtttttagca aaagtgcaac taaatcttgt gcagaatatt
    20881 cttctaataa tttatctgct gtttgcaggt atttatctag accattttct gcaagttttg
    20941 tttcgatttg ttcaactgca gcacctaatt gacctttgaa tgcttctttt tcggttggtg
    21001 gacgtaaagt cgtcatccgt tttttcgtca agttttcaat cacatgcaag tagtccattt
    21061 catttggtgt aacgaaagtc acagacatac cgccttttcc ggcacggcct gtacgtccga
    21121 tacggtgaac gtagctttct ggatcttgag ggatatcata gttgtacaca tgagtgacac
    21181 ctgaaatatc taatccacgt gcagcaacgt ctgtcgctac aaggatatct aaatgaccgc
    21241 tcttaaatga acgcaatacg ctcattcgtt tttgttgaga caaatcgcca tggattcctt
    21301 ctgcacggta accgcgtgct tctaatccgc gtgccaattc gtctacacgg cgttttgtac
    21361 gtccgaagac gattgttaat tcaggtgttt gaacatcaaa caagcgagtc atgatatcga
    21421 atttttcgta ttcttttgcg cggacatagt attgatcgat caagtcagct gtcatttctt
    21481 tcgctttgat cttcacatga tgtggatttt tcatgaattt aacgccaata ttcttgatag
    21541 ctggcggcat cgttgctgag aaaagtaatg tttgtctttg atcaggaact tgtgaaatga
    21601 ttttttcgat atcttccaag aagcccatat tcaacatttc atctgcttca tccaaaacta
    21661 atgtttgaac ggttccaagt ttcaatgtgt ggcggttaat gtggtcaagc atacgtcctg
    21721 gtgtacccac aacgatatgt ggacgatctt tcaagccacg gatctgacgg ccaatatctg
    21781 ctccgccgta aacggcttgt acacgtactt ttttgtcgcg ccctaaacga tataattctt
    21841 cttgtgtttg gatagctaat tcacgtgttg gtgcgataac taaaccttgt aattcgtgac
    21901 gatctggatc gattttttct aacattggta atccaaatgc agctgttttc cctgtacctg
    21961 tctgtgcttg tccaataacg tcttttccag ctaatgctag tggaatcgtt tctgcttgga
    22021 taggcgttgc ttcttcaaaa ccagcgcgtt cgactgattt caacaattct ggtgataatt
    22081 ctagttcttt aaatttcaaa tgaatcctcc tatatggttg ttaactgagg atgtagcttt
    22141 tttgctaccc cgtcgatttg ttcggtcaaa gtgtattgtt tctttttgac agtggccacg
    22201 cacgttttta tccattctta gcccctgtgg caccaccgaa aaatcacttt gcgaagttta
    22261 ggcattagaa aagccaaacg ggtcgcgttc agctttatca ttattatgac atctggcttc
    22321 aacaagttgt ttctatggca aaaccagtcc aatttctctt catctttcgg caataggtta
    22381 ttctaacata gtttttcgtt ttctgcaagt ttacagattt ttatttcatt tgctgaagtt
    22441 gttctaccac ttcaaataag cccatgctgt tgctgccttt tagcataata ctatctgttg
    22501 cttcaagatt ttgtttgata gcatcaatca atttattctt ttctttttca aaatagaaca
    22561 caggtagttg ggggtatttt tggttcaatt cttcttttag tgcatgcatt tgttccccat
    22621 aaaggaaaat catggcgaat ttctcaggat cgatatgttc actcatttgc gcatgcatat
    22681 ttaaagactc tttccctaat tccagcatat ctgctaacac agcgattctg cgtccttttg
    22741 ttggcagatt tttaaaagta tctaatacca gtcccatggc tgttggattt gcattgtaga
    22801 catcgctcaa aatagctgca ccatttcctg ccgttagcca ttcggttctg ttttgagtga
    22861 tagaaacatg ggcgagccct tggcgtatct caggtatgga cagtccaaag aagcgcccga
    22921 tcgtatacgc aatcaaagca ttcgttacat tataacttcc aggcagcggg atcgtaaatg
    22981 tttctccttc tactacaaaa tcggtttgtg cttttccttt tgctgtcact tccgcatgaa
    23041 catcgccatt tccaataccg aatgttgtga ctgtttgtac taatgttgcc gttaaaggtg
    23101 tcagcaacgg ttcatctgcg ggcacaacga gtaatccgtc tgatacaagt ccgtcagtga
    23161 tttccatttt ggctttagcg attccttctc gcgacccaag attttctatg tgtgcttcac
    23221 cgatcattgt gattgctgca gcttttggtt gagccataag tgaaagttcc gtgatttcat
    23281 tggcgtgatc catgcccatt tccaaaacga tcttttctgt atcttggggc atgtgcaaaa
    23341 tcgtgtaagg aagaccaata ttattgttgt aatttccttg cgtcttatat gttttgtatt
    23401 tttcagacaa gacagacgcg gttagatctt tcgtggtggt tttaccattg cttcctgtaa
    23461 ttgcaacgac ttctgcgcct actttttcca agtaataggt tgccaattgc tgcatggctt
    23521 tcaaaggatc tgctacagga ataactggaa aattttttgg agcttgttca acaggcaagc
    23581 tccaaaatga agcagatgct ccgtttgtga tcgcttgctg gataaattca tgtccatctc
    23641 gcgtaccagc aagaggaacg aataaacttc cttcggttat cttccggctg tcaaattcga
    23701 cattggtaat ctttgtcagt gcagagcatt cgctgcccac ggcttgtgca atttcttgta
    23761 ttgttagatt cattgagatc tctcctaaaa aaggttgtga aaaaagcgtt tggcctaaac
    23821 ggcgggttcg catgactctc acttccaagt aaatttctct attcgtattt agaagctaga
    23881 atgaacgcgg ttacgcaatc actccagcct cttctttatt tctctttatt catttttttc
    23941 aaaaaaagat tgacgctgat ggtatcgatt cattcctaac tggatcagtt cttcaatcaa
    24001 atcaccgtat ttcaagccca tattttccca taagagtggg tacatactga actccgtaaa
    24061 tcctggcata gagtttaatt cattcaggaa taattcattt ttatttgtca aaaagaaatc
    24121 gcaccggctc aatccgcttc cacctaacat cgtgtaagct aacttcgcgt actcttgcgc
    24181 tttttgataa acttcttctg gcacttcggc tggaatctgc atttcgattt tattattgat
    24241 atattttgct tcataatcat agaatgctac gtcttttacg acttcaccag gcaaagtcgt
    24301 ccgaacgtct tcatttccta atacagcaac ttcgatttcg cgcgcttcaa ttccttgttc
    24361 aacgattgct cgagaatcat actgataggc tgttgctaaa gcattttgca gctcttctcg
    24421 gttttctgct tttgtaatgc cgacactaga acccatattc gccggtttga caaacatcgg
    24481 ataaagcaaa gaaccttcac attgatcaaa tactttttta ggattttctt tccattgatt
    24541 cttaagtact ggtacataag gaacttgcgg cacaccagca gcttgtaaaa tatacttggt
    24601 catgatttta tccatggcac atgcactggt caatacgcct gcgccgacat aaggcatatt
    24661 caatgtctct aagaagcctt ggatcgttcc atcttccccg tttggcccat gtaaaactgg
    24721 aaaaacgatg gctccttctt ctttgatttc gcccggattg atcacttttc ctgtaaagcc
    24781 ttcctctgtc tgtccacttg ggtcccatga aagatgcaag acatctttgc tggcaggttt
    24841 ttctgttagt aatggacctt tgacccattg tccttctttt gtaataaata cgagttgaac
    24901 ttggtaataa ttataataaa tggcatttaa aactgaaaat gcggaaagaa tggacacttc
    24961 atgctctgcg ctgcgtccgc catatagtaa agtaatcttc aaaagattgt cctcctgtat
    25021 tctaaatcgt tcagtgattt actctcatat tttagcacaa aacaaaaata aacgaataac
    25081 ttatttataa aaaaacgagc cagcttctaa aagaacgagc gtcatttatt ttttgtcagc
    25141 tagattattt gtcccgtttt ttataaaaag ttatgataaa gaaaaggagg gatgatgatg
    25201 gcgcaaacaa atccacgcag ccgcttggca gaaatcattc gagtgttcat caattacaat
    25261 gtagtgccaa actttgtaca gcaaaaaaat cccgaacagg taaaaaaagc ctttgaagaa
    25321 ctaggcccca ccttcatcaa gataggacag atgctttctg ttcgagaaga tttgctttct
    25381 tctgccttca ctcaaacatt caaaacatta caagatagtg tacctagcga cacattttca
    25441 acggtcaaaa agacgatcga aacagaactt tctctttcat tatcagatat attcgatgat
    25501 ttttcaaaat cgccttttgc ctctgcttct atggggcagg ctcatcgtgc caagctgaag
    25561 aacggtgacg cggtagtcgt taagatccaa caccctaaca tcgccgaaga gatccgactt
    25621 gatcttcaac tatttgaacg agcgatccct ttgatcaaat acattcctga aactagcgta
    25681 gttgatctaa aaggggtact ccaagaagta aaacgttcct tgatcaatga aatggacttc
    25741 ttaaaagaaa gtcaaaatgg cgaacaattc tatcaaaaga acaatggctg gaaagagatc
    25801 cgcagcccca agatttatga cgctttttgt tcgaaaaaag tgatcgtgat ggaagaaatg
    25861 tctggtaaaa acttgaatca tttaatgaac gccgaaaaca aaactgaaac ttttatcact
    25921 ggaattcaaa acaagcagct gaaacaagaa gttgcaaagc ttttagttga gaactttatg
    25981 aaacaggtgt ttgatgatgg ttttttccat gctgatcctc atccagggaa tctgctattc
    26041 catgtactaa caaaagaaga acagacacaa gctagccgaa aaactgaaac agtccatgaa
    26101 aaagagttcg gttcctttgc ttttcgagcc tccacttctg cagaagaccc tgttgcgcca
    26161 tataccatca actacatcga ttttggtatg atggggcatc tttctgcagg acttaggcaa
    26221 aaactcacac aagccgtttt agcgctgtat acgaaagatg cttatcgaat cgaaaaagcg
    26281 gtccttcgac tttgtcagca agaaggctcg tttgatgaaa gtcggttcca ccaagaactg
    26341 acaagttttc ttgaacagta ttatgattct cctattgatg aaatcaactt gcaagaagta
    26401 ttcacacatg tcgtgacgat ttgtcatcaa aataatctgc agttcgatcg tgatatcacg
    26461 cttttgctga aagcatttgg gacattagaa ggggtgatcc gcgtcctcga tcctgaagtt
    26521 tccctcatgg aagtcgcttc gccttttgct caacattatt ttctcactca tctggatgta
    26581 gaagatacat tgaaacaaag cggattagac ttattggaag ggatgaaggc tgcgcctaag
    26641 atccctcaac agctccacca tctattagaa atgtggactt cgggacaagg aaaagtcaat
    26701 ttggaattga aaaagcaaga caaattattg agcaggatcg aaagtatgat caatcggctt
    26761 gttttcggta tgattttagc tgcattgatc gtagggtcct ccctgcttgt ccaagcagca
    26821 cctgtagaaa acgcagaggt cgtttcctta ttagggatat ttacgtatgc tattgccgca
    26881 ttcgtcatta tttttttggc aatcgatgca ttgatccaaa tgtataagaa gaggaaaaag
    26941 tagaaaaagg ttgtgacaga aagaatcagc ttcaagaaat aagaaggggt tttacataaa
    27001 ttgtttctca aatttttgtg aaaattcggc ttatttttcg aagaggctac ttctgaaaca
    27061 ccgagaataa aaaatgtgaa aaagctgttc tgcacccagt aataagaaca atcaaaaagg
    27121 gaacatggaa cacatttatc ctgtttccct gttccctttt tgatgtattc gagcataaat
    27181 aaaatacctt cgttacctac tatcttctgt acttggtaaa ccttagtcaa ttgccttttt
    27241 taacgcttga cgaaaagaca tatgatcttt ctccgtaaag ggttttggac cctttgtcct
    27301 tatgccagct tttcttaact ttccactatg ataacgttgt tctagaagcg tgccgatatt
    27361 cgcttcgtca aattcttttc cagagtgatg gaacactcgc acacccttcg gcaatacaag
    27421 tgaagctaaa ccataatctt gcgtgatcaa aaagtcattc ttcttaacca taccgacgat
    27481 tttataatcc gcactatcag ctccgcggtc tacgtagacg atttggacat gattagcgta
    27541 ttctttggtc gtataatggt ccacactggt cacgataacc acgtcaagac cataggattc
    27601 tcctaatttt atgacatctt cttttactgg agaaccatct ccatcaatga atagcctcat
    27661 tctttttcgc cttcttccat aaatgataaa cagttactaa tccgctcagt aaaagaccaa
    27721 cattgatcca ttttgccaag ataagcagtt gtacactttc tatcggcact gattcatggt
    27781 tcagcgtgat caataataga tggattggct ctcccatttc ttttgctaaa acaaacaaaa
    27841 gcgtcatcaa taaaaactgg tggatcacac tccctttatt ttgagtagta tacttgacaa
    27901 cgatccggcg atccattgga atagctgtat cagtttgata atattcctta tttagccagc
    27961 tgcctgttac tacgtgccag aaactaagca gaaagacacc tatcgcaaaa ccatttggaa
    28021 tcaagaggac caataaagaa gaactcagtc caagcaattg catagccaat ggagaccatg
    28081 ttaaacgttt caaaatccat ggtccgacta tttttgctgc aatcaagcct gctgcataag
    28141 gcaaatacat aaaaatcgaa agtttttcta atccgtacag tatgccaaca taaaaactgc
    28201 taaataaaaa aaggaaattc cctagcattc catttagaaa agtaaacaga tttagccagc
    28261 ttggcaactt ccattccttc ttctggtgtc ctaaaacaaa cacgaacaag atgaacagca
    28321 gcaagaaacc ataaatagca agatcaaaaa gcctttcatc gaataacaat cgggcatttc
    28381 tcaaaagaaa caataagcca aagaatatca aaaataaaac aagctctcgc gtagctacca
    28441 gatttctttt gatgtctttg aaatccagtt cgtaacgcgg ataatgacta accgtatggt
    28501 aggccatgac gtaaaaaagt gtataaatag taaagcttgc tgcaatctga gtcggtgcag
    28561 gcaactcaat cgcttgatac aggagaaata gccagatagc tgcaaataag tactttttcc
    28621 catccatatt gataaaacct tgcgtctttt cgtgaaaatt gaccgtggta ttagcaggta
    28681 caagccatgc tgcactcagc cctagcaaaa cacttgaaaa ataaaataaa ggaaaataaa
    28741 atacgcctaa tattccaagc aatgaaccag caccaccaat cagcagagcg atcatcagca
    28801 acgtgtaact atctagacca aatcgtagac tgttgactaa aaatagtcca gtcatccgaa
    28861 aggcataaaa cagcgtaaat ggcaaaatcg tcagccaatt atgcgagtct gttagtccca
    28921 aaaataaaag ataaggaata aaaataaccg tgttacttaa gataaagggc gttgtttgtg
    28981 taaaattacg cccaaatcgt ttgagttttt cgaacatgac aatggctcct taaacagtct
    29041 tataactaat ctgctcttcg attttagcat taaaggggaa ataaaccaat tttacagaat
    29101 atattcttgt aaaaaaaaat acagaaagaa gcataagctt ctttctgcat ttttacggta
    29161 cttgattact caagcagaca agcccttctc cacaaaagtc ttgcccgaca cccctgcatc
    29221 cggcaggtga taaagataga aatcaattat cctgtgcctc caaaatcaat taggagctct
    29281 gtaaaccaga gtccttctcg acccgtcgca taaatttact ttaacacagt tcctatgttt
    29341 atgcgagagc ttttttcatt ttataatcga ccatttgaaa tccttgaccg atatctgaaa
    29401 taagttcttc tgtaatctca aatccttcat gcttataaac ctcgattgct tgatgattcc
    29461 cctgattcac tcgcaaaaag atctctcttt cctttgtttg cgcagcaagt tcttcatacc
    29521 agcgaaaaac tgaagaagtc aatccttgac cacgtacttt atttagcaaa tataatttac
    29581 ttaaataaat ttttccattt atctcttcat aagcagtgta accgacagtc ttttcttcgc
    29641 tttttaataa aaagtaggac acaccttctg tcagttcttt ttgaatctgt ttttttgact
    29701 gataagtttt cagcatgtaa tccacttgtt tttgaccaat gatcggcaca aaaacttccg
    29761 gccatacttc ttgtatgact gccatcagct catccagttc attttctgtt acttttattt
    29821 tttccataca cccacgtcct tttttacatt ataaatgacc ttgcgcttga tggaataaaa
    29881 agagcatgat catgctatac acacccaccg accacggttt caagaaaatc acaatctgca
    29941 taaattccct aaaagataat ttcgtcaaac cagctactag acagatcaag tcgtctggcg
    30001 caaagggaag cagcaaggta acaactagta cttttttaat atctttcgtt tttcttgtca
    30061 gcaattcatc aaatttctga tacttttttg gcgataaaat aagctggaca aaggctacgc
    30121 catagtaacg gacaagcaaa aatccgattg cttccccaat cactaggcca atacaactat
    30181 ataaaagccc aaatccattg ccaaacatca gcatgcccgc tactgaggag atccctcccg
    30241 gcaaaatagg aatgatcact tggatcactt gcaacagaac aaatatcatc actgcatact
    30301 tgccaaattg ctggataaac gcttgcaaag acgtgctcga tcgaaaaatc ccatgatgat
    30361 aagcataaag aatcaacaca aagaaaaaaa acagaccaat aatgggcatg atctgaagac
    30421 atttttgtaa aactgatcct tttttagaca tctatattcc ccacatcttt tttcatttat
    30481 taaaactgcc tcct
//
LOCUS       DAFTHM010000025        29666 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFTHM010000025 DAFTHM010000000
VERSION     DAFTHM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.025"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(114..473)
                     /gene="rplT"
                     /locus_tag="L7C88_001125"
     CDS             complement(114..473)
                     /gene="rplT"
                     /locus_tag="L7C88_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBP9557970.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(526..726)
                     /gene="rpmI"
                     /locus_tag="L7C88_001126"
     CDS             complement(526..726)
                     /gene="rpmI"
                     /locus_tag="L7C88_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBP9557971.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(798..1322)
                     /gene="infC"
                     /locus_tag="L7C88_001127"
     CDS             complement(798..1322)
                     /gene="infC"
                     /locus_tag="L7C88_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBP9557972.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1366..1491)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            1642..2274
                     /locus_tag="L7C88_001128"
     CDS             1642..2274
                     /locus_tag="L7C88_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBP9557973.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2276..3181)
                     /locus_tag="L7C88_001129"
     CDS             complement(2276..3181)
                     /locus_tag="L7C88_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBP9557974.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(3266..3925)
                     /locus_tag="L7C88_001130"
     CDS             complement(3266..3925)
                     /locus_tag="L7C88_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBP9557975.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            4241..5185
                     /gene="mvk"
                     /locus_tag="L7C88_001131"
     CDS             4241..5185
                     /gene="mvk"
                     /locus_tag="L7C88_001131"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBP9557976.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5178..6155
                     /gene="mvaD"
                     /locus_tag="L7C88_001132"
     CDS             5178..6155
                     /gene="mvaD"
                     /locus_tag="L7C88_001132"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBP9557977.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6168..7253
                     /locus_tag="L7C88_001133"
     CDS             6168..7253
                     /locus_tag="L7C88_001133"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBP9557978.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7250..8314
                     /locus_tag="L7C88_001134"
     CDS             7250..8314
                     /locus_tag="L7C88_001134"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBP9557979.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(8563..9366)
                     /locus_tag="L7C88_001135"
     CDS             complement(8563..9366)
                     /locus_tag="L7C88_001135"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBP9557980.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9386..10228)
                     /gene="kduI"
                     /locus_tag="L7C88_001136"
     CDS             complement(9386..10228)
                     /gene="kduI"
                     /locus_tag="L7C88_001136"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBP9557981.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(10244..11251)
                     /locus_tag="L7C88_001137"
     CDS             complement(10244..11251)
                     /locus_tag="L7C88_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBP9557982.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(11258..11902)
                     /locus_tag="L7C88_001138"
     CDS             complement(11258..11902)
                     /locus_tag="L7C88_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBP9557983.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(12002..12760)
                     /locus_tag="L7C88_001139"
     CDS             complement(12002..12760)
                     /locus_tag="L7C88_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBP9557984.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(12887..14038)
                     /gene="fucO"
                     /locus_tag="L7C88_001140"
     CDS             complement(12887..14038)
                     /gene="fucO"
                     /locus_tag="L7C88_001140"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBP9557985.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(14120..14431)
                     /gene="rhaM"
                     /locus_tag="L7C88_001141"
     CDS             complement(14120..14431)
                     /gene="rhaM"
                     /locus_tag="L7C88_001141"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBP9557986.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(14433..15278)
                     /gene="rhaD"
                     /locus_tag="L7C88_001142"
     CDS             complement(14433..15278)
                     /gene="rhaD"
                     /locus_tag="L7C88_001142"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBP9557987.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(15292..16548)
                     /gene="rhaA"
                     /locus_tag="L7C88_001143"
     CDS             complement(15292..16548)
                     /gene="rhaA"
                     /locus_tag="L7C88_001143"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBP9557988.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(16545..18005)
                     /gene="rhaB"
                     /locus_tag="L7C88_001144"
     CDS             complement(16545..18005)
                     /gene="rhaB"
                     /locus_tag="L7C88_001144"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBP9557989.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            18158..19027
                     /locus_tag="L7C88_001145"
     CDS             18158..19027
                     /locus_tag="L7C88_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBP9557990.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(19153..20052)
                     /locus_tag="L7C88_001146"
     CDS             complement(19153..20052)
                     /locus_tag="L7C88_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9557991.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(20217..21041)
                     /locus_tag="L7C88_001147"
     CDS             complement(20217..21041)
                     /locus_tag="L7C88_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBP9557992.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(21052..22347)
                     /locus_tag="L7C88_001148"
     CDS             complement(21052..22347)
                     /locus_tag="L7C88_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBP9557993.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(22363..22842)
                     /locus_tag="L7C88_001149"
     CDS             complement(22363..22842)
                     /locus_tag="L7C88_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBP9557994.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(22848..23876)
                     /locus_tag="L7C88_001150"
     CDS             complement(22848..23876)
                     /locus_tag="L7C88_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBP9557995.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(23893..24999)
                     /locus_tag="L7C88_001151"
     CDS             complement(23893..24999)
                     /locus_tag="L7C88_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBP9557996.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(25228..27825)
                     /gene="adhE"
                     /locus_tag="L7C88_001152"
                     /gene_synonym="adhC"
     CDS             complement(25228..27825)
                     /gene="adhE"
                     /locus_tag="L7C88_001152"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBP9557997.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(28130..28510)
                     /gene="yajC"
                     /locus_tag="L7C88_001153"
     CDS             complement(28130..28510)
                     /gene="yajC"
                     /locus_tag="L7C88_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBP9557998.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(28607..>29666)
                     /gene="tgt"
                     /locus_tag="L7C88_001154"
     CDS             complement(28607..>29666)
                     /gene="tgt"
                     /locus_tag="L7C88_001154"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBP9557999.1"
                     /translation="TFPTPMFMPVGTLATVKTMSPEELKEMGAGVILSNTYHLWLRPG
                     EDLVEEAGGLHKFMNWDQPILTDSGGFQVFSLSDMRNIEEEGVHFKNHLNGSRMFLSP
                     EKAINIQNKLGSDIMMSFDECPPFDESYDYVKKSVERTSRWAERGLKAHANPDRQGLF
                     GIIQGAGFEDLRRQSAKDLVGMDFPGYSIGGLSVGEPKSEMNRVLEFTTPLIPENKPR
                     YLMGVGAADSLIDGVIRGVDMFDCVLPTRIARNGTCMTSQGRLVVKNAKYAHDFRPID
                     EKCDCYTCKNYTRAYIRHLIKCDETFGIRLTSYHNLYFLLNLMKQVRQAIMDDNLLEF
                     REAFFEEYGFNKENAKSF"
BASE COUNT         8356 a         6497 c         5330 g         9483 t
ORIGIN      
        1 tattttagac ttatacgtta ttgtcctgtt tcatttgatg gaggattgta aataaaaaaa
       61 gaggaaagaa cataactttt cgttatcttc tttcctcttt ataattgttt agcttattta
      121 gccaaagctt cttttgcttg gtcagccaat gcagtaaatg ctgctgcatc gttaacagcc
      181 aagtcagcta acattttacg gttgatgtcg atttcagcaa ctttcaaacc gtgcattaat
      241 tttgagtagc tcaagccatt catacgagct gctgcgttga tacgagcaat ccacaattta
      301 cggaagtcgc gtttcttttg acgacgatcg cgatatgcgt agttgtatga attcattact
      361 tgttcttttg ctgttttaaa taaagtgtgt tttgaaccgt agtaaccttt tgctaatttt
      421 agcactcttt tacgacgttt acgagttact gttccacctt taacacgtgc catgtataat
      481 tcctcctaat aaaaataaat cttcagattc tgttatttgt acttcttatt tcatttttgc
      541 tagttgttgg cgaatacgtt tgaagtcgcc actagaaacc atgcttgctt tacgcaattg
      601 acggcgttgt ttttttgttt tgccgtggaa acggtgactt gtaaacgcgc ggaagcgttt
      661 caatccgcct ttaccagtac gtttgaaacg ttttgctgat ccgcggtgtg ttttttgttt
      721 tggcatgact atatttcctc ctcaaaatct ttcgttatcc gactatcggc tgtccaacag
      781 ccagttagtc attcaaatta cttactgtcg tttttcggtg ccagcgtcaa gaacatgctg
      841 cgtccgtcca ttttcgcttt ttgttccact gttgcaatat ccgcagtttc ttcagctaag
      901 cgattcaaga ctttttgacc aatttcttta tgggtaatgg cacggccttt gaaacggata
      961 gaagctttca ctttatcgcc cttttccaag aacttacgtg cattacgaag ttttgtattg
     1021 aagtcattca agtcgatcgt aggacttaag cgaacttctt ttacattgat cactttttgt
     1081 tttttacgcg cttcgcggtc tttcttttgt tgttcgaaac ggtatttacc gtagtccatg
     1141 attcgcgcaa ctggtggttt cgcaccaggg gcaactaaca caagatccaa gtttgcttgt
     1201 tctgcaatat tcaatgcttc tgcttttgtc ttaactccta attgctcacc atctgaaccg
     1261 atcaatcgta actctcgtgc acgaatgccg tcgttaacca tcatatcctt tgctatggtc
     1321 attcacctcc aaatattatg agagaaagaa aagcttaccg aataaacggc aataaaaaaa
     1381 cgagttctct tacagaaccc gcgcgtactt cacctaatag aaccagtgaa aactatctag
     1441 cccagtgaca ttatcaacta aggcgagaag cgggtgcttc tgcttttatt tctcaaccat
     1501 catagtatag caaaaactaa tctttttgtc aatgtttttc atacagtttg tcttcctttt
     1561 ctgaaaatga ttagattagc agactttcta gcagtgattc ccgcttcttt gctatactaa
     1621 agaaaaacga ggtgaaccca catgaaaaaa atcgaaccta ttccaccttc tcttcctctt
     1681 cttacaaagg gagagtttta tttagaagat gaggagatct tctctggtct tctgatcaac
     1741 gggggtgacc aaagctatct cgatgccaaa aatatggtat taagagagag tcatatccaa
     1801 aaacttacga tgcaaaaaac agttttacgt cattttgaat gcagtaatgt catttttgaa
     1861 aaatgtgatt tttccaatct ggagtggatt ggtggcagtt tccaccaagt cgtgtttcat
     1921 caatgtaaat taacaggtac gaattttgcc gaaagttatc ttcgagactg tactttcact
     1981 gattgtattg cttcgatggc ttcctttagt agtacaaact tgaaagctgt ctccttcgat
     2041 cattgtcaat tagaagacag cgaattttat gaggtcactt ggaaaaacct ttttttgtct
     2101 gacaatcagt tgaccggttc gaactggttt cgaacttctc tgaagggatt agactttacg
     2161 actaatttct tcacagcaat cgctttatct caagattctt tggcgggact aatcgtcaac
     2221 caagagcaag cacttgtgat cgcccaagcc cttggtttgc agatcaaaga ctagatcaac
     2281 gaatccgccg ccacagtgca ataagcatcc aaatagataa gaccaaactg atgatcaagg
     2341 cgattcccca tccgaaaacg gaatgggtaa agggtaactg gagattcatt ccgaagaatc
     2401 ctgtcacaat agttggaacg gtcaagatca gcgaccagac cgtcaaaaat ttcatcgtgt
     2461 cattcaagtt gttattcagc aaattattat aagtgccaga gagctggtct aaaatctgcg
     2521 aagctaagtt cgtcatttca actgcttgtc gtgcttcgat cagcgcatcg tccaactctt
     2581 ctttttcctt ttctgacaac ttgcgataaa tagccaatgc cttgatttgt tctaaaagta
     2641 ctacattttg ttttgttcct gtaactaagt aaaccaaacc gatctctaaa tctgaaagtt
     2701 gcagcagatt cttgttcgtt gttttttctc ttaatttcag attaagccgc tgacgttcac
     2761 tattcacttc ctcgattaaa ggaaaaaagg aatcagaaat caaaaacaat gtacgaaaca
     2821 ataaactgta tacactcatg tctggcattc gttccaaaag cgatcgaatt agtcgaatca
     2881 cgtactcggt attcggcgtg gtaaatgtaa acaaaccgtc ttcttttaaa ataaaagcga
     2941 taggactagt ttcataatga ttatcgactt tttgctggtg cggaacattt gatacaagca
     3001 gtaacgcttc atcaaaagaa tcgtactcta cgcgcgcccg ttcattttta tctagagaat
     3061 aagtcagcat ctcgtcacta atgccatatt cttcttttaa gtttttaaca gctagcacat
     3121 cgttttgctg tacattgatc caaaaattac ggtcttgatt aaaatagtgt ttttcccgca
     3181 tactctatcc tcctgacatt tgtttccagt ataaagaaaa aagtcgctca aataaaggtt
     3241 taccctttat ttgagcaact gtaaatcaaa tggctacttt ggtttggcga atctctgcta
     3301 atttttcttc gatcattttc aagacttctt cttttgcttg aggatcttcc acaaaattat
     3361 agcggtctcc atcgatttgg atttttggac tttctttgta ttcttcatac cattgatcgt
     3421 aacgtctgtt caattctttg taataatcgt atagacttgg atcaaaggac aattgttcat
     3481 acgaacgacc acgtttttcg atacgctcca acatcgtatc aaaagataca cgaatatgaa
     3541 ctaataaatc cggatgtttt ttatgggcag catagggaag ttcttccatc atgttttcca
     3601 gcagttcatc atacacacga acttctgttt ctgttgctct tcctagatct gcatttagat
     3661 ggaaaagcag tgaatcttca taaatcgaac ggtccaatac attattgtca tctttcattg
     3721 cttgtttgat gcttgcaaaa cgtttattca aaaaataaat ttgcagcaaa aaagcatact
     3781 gttcagggtt tgcataaaat aagggcaaga cttcattatc atcaatcgat tcataaaatg
     3841 cctgactatc aaagtgttca gccatcattt ctgttaaact tgattttccg gcaccaattg
     3901 tacctgctaa aacgatcacg ctcatttacc tccagctcac ttcatcacta aatattgtgt
     3961 ttaactccaa cctttttaaa tataccccca atatctagta gtgtcaattg tatttttttc
     4021 tagtcaaaga agaaaaaaag tcaaaaaatt cttaagaaaa aagtgttttt tctttagaaa
     4081 acgtattctt agttttactt ctgagatggt tttagtaaaa taaaggagga atgttttttg
     4141 agacccttag tggacaaaaa aattcgtgaa gcagcgcaac tcgttttggg cgctttattt
     4201 tttgcttaaa aatcactttt acgtgagaag gagttagatt atggcaaact atggccaagg
     4261 agaatcaagc ggaaagatca tattgatggg cgagcacgcg gttgtttatg gagaaccagc
     4321 gattgccttt cctttctatg caacaaaagt caccgcattc cttgaagagc tggatgcaat
     4381 ggacgatcaa ctggtttctt cctactattc aggaaattta gccgaagctc ctcatgcatt
     4441 aaaaaatatc aaaaaattat tcattcactt aaaaaaacag catgacatcc aaaaaaactt
     4501 gcaactgacc attgaaagca cgattcctgc tgaacgtgga atgggatcaa gcgctgcagt
     4561 cgccacagca gtcactcgtg ctttttatga ttacttagca tttcctttgt ctcgtgaaat
     4621 actattagaa aatgtccagc tttcggaaaa aatcgcccac ggtaatccta gtggaatcga
     4681 tgcagccgct actagcagct tgcagccgat ttattttaca aaagggcatc ctttcgacta
     4741 cttttctttg aacatcgatg cttttttgat tgtcgctgat acaggaatca aaggacaaac
     4801 aagagaagcc gtcaaagatg tcgctcacct ctttgaaacc cagcctcatg aaactggaca
     4861 aatgatccaa aaattaggat acttgacgaa gcaagcaaaa caagcaatca ttgaaaattc
     4921 accagaaacg ttggcacaga caatggatga atcacaatca cttctggaaa agctgacaat
     4981 cagcaatgat tttcttaatc tattgatcca aacagcaaaa gataccgggg cattgggtgc
     5041 caaattaact ggcggtggac gcggtggctg tatgattgca ttagcacaaa caaaaacaaa
     5101 agcccaagaa atcagtcaag cacttgaaga tgcgggtgct gctgaaactt ggatacaagg
     5161 attaggagta catacctatg tttaaaggca aagcacgcgc atataccaac attgctctaa
     5221 tcaaatattg gggtaagaaa aatgaagaac tcatccttcc aatgaacaac agcctttcgt
     5281 taacattgga tgcattttat acagagacag aagtcatctt ttctgatagc tatatggtag
     5341 atgaatttta tctagatggc accttgcaag acgaaaaagc aacaaaaaaa gtcagtcagt
     5401 ttcttgacct ttttcgtaaa gaagccggcc tctcactaaa agcttcagta atcagtcaga
     5461 atttcgttcc taccgcagct ggattagcct cctctgccag cgggctagct gctttagcag
     5521 gcgcttgcaa tactgctctt aagcttggat tagatgatct ctctctttca agatttgctc
     5581 gacgcgggtc tggttcagct tgccgaagta ttttcggtgg tttcgtcgaa tgggaaaaag
     5641 gccatgacga cttaagttct tacgctaagc cagtcccttc cgattctttc gaagacgatt
     5701 tagcaatggt tttcgttttg atcaacgacc agaaaaaaga agtgtccagc agaaatggga
     5761 tgcgtcggac agtcgaaaca tccagttttt atcaaggctg gttagattcc gttgaagggg
     5821 atctatatca attgaaacaa gcaatcaaaa caaaagattt ccaacttctc ggagaaacga
     5881 tggaaagaaa cggactaaaa atgcatggaa cgactttagc tgcccagcct ccattcactt
     5941 actggtctcc tgacagctta aaagcgatgg atgcggtgcg acaattgaga aagcaaggca
     6001 ttccatgcta ctttacgatg gatgctggcc ctaatgtcaa agttttagtg gaaaacagcc
     6061 atttatctga ggtacaagaa acatttacca aattatttag caaagaacaa gtaattactg
     6121 cacatgctgg tccaggaatt gcgattattg aataaaggga gatttttatg attgaagtat
     6181 ctgcaccagg caaactctat attgccggag aatatgcagt tgttgaaaca ggccatccag
     6241 cagttatcgc tgcagtcgat caattcgtga cagtcactgt agaatctgca cgaaaagtcg
     6301 gaagtatcca atctgcacaa tatagtggga tgcctgtacg ttggacaaga cgcaacggag
     6361 aattagtttt agatattcgg gaaaatcctt ttcattatat ccttgctgct attcgcttga
     6421 ctgaaaagta tgcacaagaa aaaaacattc ttttatcctt ttatgatctg aaagtaacaa
     6481 gtgagttaga cagttcaaat ggccggaaat atggattggg ttctagcggt gccgtgaccg
     6541 ttgcaacggt caaagccttg aatgtttttt acgcgttgaa tttatctcag ttggagattt
     6601 tcaagattgc agcactagcc aatttagcag ttcaagataa tggttcctgc ggcgacatcg
     6661 ctgctagctg ttatggtggc tggatcgctt tctcaacctt cgaccatcct tggctccaag
     6721 aacaagaaac tcagcattct atcagtgagt tacttgccct ggattggcca ggtctatcca
     6781 ttgagccatt gattgctcct gaagatttac gtttattgat tggttggacg ggtagccctg
     6841 cctctacttc tgatttggtc gatcaagttc accgttcgag agaagataaa atggtggctt
     6901 atcagctttt cttaaaaaat agtacagaat gtgtcaacga aatgatcaaa gggtttaaag
     6961 aaaataatgt aacgttgatc caacagatga ttcgaaaaaa ccgacaatta ctgcatgatt
     7021 tatctgcaat cactggggtc gtcatcgaaa cgcctgcttt gaacaaattg tgtaatttag
     7081 ctgaacagta tgaaggagcc gcaaaatctt ctggtgcagg tgggggcgat tgcggaatcg
     7141 taattgttga ccagaaatct ggcattcttc ctttaatgag tgcatgggaa aaagcagaaa
     7201 tcactccact gccgttacat gtctatagcg atcaaagaaa ggaaaaccga tgaatcgaaa
     7261 agacgaacat gtttcactag ctaaagcctt tcatgataaa caaaaaaacg aatttgactt
     7321 cgtacggatc atccataacc ctttgccgca aatagcagtt tctgatgtcg atctaagtac
     7381 acaggcagtt gggtttacac taagcagccc attttatatc aatgcgatga ctggcggaag
     7441 cgaaaaaaca aaaaaaatca accaagatct tgcaatcgtc gcaagagaag cagatttgat
     7501 gattgccact ggttcagtca gcgctgcctt gaaagtccct tctttagccg atacttatac
     7561 gattatgcga caagaatatc ctcacgggaa aatcattgcc aacatcggtg cagggacttc
     7621 tgtcgaaaga gccaaagaag ctatccgatt gtttcacgca gatgccttac agattcattt
     7681 gaatgcacct caagagttgg ttatgcctga gggagaccgt gattttacca attggaaagt
     7741 acttattcaa gaaactcaaa cagccattga cgtccccctc atcgtaaaag aagtcggttt
     7801 tggcatgaca agagaaacgc tcaatgatct agctgcttta ggagttcata cagttgatat
     7861 cagcggtcga agcggaacaa gcttcaccca gatcgaaaac gcccgtcgct ccaagcggga
     7921 actgagttat ttagctgact gggggcaatc gacagtctct tcattgcttg aagcaaatga
     7981 agcagacact tctatggaaa tcctagcctc cggaggtatc cgcaatgcct atgacatatt
     8041 taaagccctt tgtctcggcg caaatgccgt gggtacttca ggaaccgtac tgacgcatct
     8101 gatgaatcac ggcgtagaag aaactattat actgatgaag caatggcaag aagagcttcg
     8161 tctgctttat actatggtcg gcgcaacgaa taccgcggcc ctacaccaac aatctctgat
     8221 cttttccgga ccagtgaagg attggtgcga agcaagaggg atcgacttag tgaagtatgg
     8281 aagacgcaca gaaaagagcg tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa
     8341 cacgtacaaa cggcggaagt aaaagcaact ccttcggaaa taagctgaaa ttcacaaaaa
     8401 tttgaaaagc aattttcgtg aattccttct tatttcttgg agttaaatgc ttctgtccca
     8461 gcctcttttt tcgaataaat gatgtttaat cagctgtcct tcggtattcg ttcaatccgc
     8521 tgatttcaca acctctccac taaacagtgt actaaagctc ttttaaggtt gttttccgat
     8581 ataggcaagt atgcctccgt ccacatacaa gacatggccg ttaacgaaat cagatgcgct
     8641 agaagccaag aagacagatg gtccagccaa atcgattggc tcgccccagc gtgctgctgg
     8701 cgtacgtcca acgataaatt gatcgaatgg atgacgttca ccgttttctt gtgtttcgcg
     8761 taatggagca gtttgcggtg tagcaatata acctggtcca attccattac attggatatt
     8821 gtattgaccg tattcagaag cgatgttttt cgtcagcatt tttaatccgc cttttgccgc
     8881 agcataagca ctgaccgttt cgcgtcctaa ttcactcatc atggagcaga tattgatgat
     8941 tttaccgccg cctttttcga tcatatccgg aataactgct tttgaaacga tgaatggggc
     9001 atttaaatcc acgtcgatta cttggcggaa gtctgccgca tccatttcga tcatcggtgt
     9061 ccgtttgatg atccctgcat tgttgactag aatatcaact gaacctacat cttctttgat
     9121 ctgttgaacc atcgcttgaa ccgcttcttc atcggtcaca tcgcagacat aaccttttgc
     9181 atcgatgcct gcttctttat aatgcgctat accttcatca actgattctt gattcaagtt
     9241 attaaatacg atttttgctc ctgctgtagc taaagagcgt gcaatctcaa atccaatacc
     9301 atagacagca ccggtgacta atgctacttt tccatctaaa cgaaacatat ccatactaaa
     9361 ttccatcatt ttctctccct tatgcttatt ttaattgatc catttgcacc atatccatgt
     9421 ctgtataggt gatattttct ccgcacattg cccagatgaa tgagtaattg cttgtaccta
     9481 cacctgaatg gatcgaccag cttggcgaaa taatggcttg ttcattgtct acaactaaat
     9541 gttttgtttc atctggtttg cccatcatgt ggaacacacg tgtatcttca ttggcataat
     9601 caaagtagac ataagcttcc atacgacgtt catgtgtatg acaaggcatc gtattccaag
     9661 cgcttcctgg ttctaaaatc gtataaccca tttgtaattg acagctttcg catacatttg
     9721 gatggatgta ttggtagatt ttacgttcat tcagtgtcag gccttcacca gtctccattg
     9781 gttttacttg gtcgatactg atttttacat ttggatattt atgatgagct ggaacagaac
     9841 taatatagaa tttagctggg ttttcagcat cttgagaaga aaatacaaca tgtcgtgttt
     9901 cttttccgat atagtatccg tcttgttttt tcatttcttc tttttgccca tcgatctcga
     9961 tgaatcctgg tccaccgata ttgatcacac ctagttcacg acgctctaag aagtaatcaa
    10021 cacctagttc tttgtctaat gtgatttcta attctttttc agtaggtgtc actccaccaa
    10081 agatcattcg atcgttgtgc gtataagtca aactgatttt ccctggttca aatacctttt
    10141 ctactaaaaa ttcttttctc aattgttccg ttgaataatg acggatatct tctggactgt
    10201 gtgtataacg tgtttccatt tcttgcattt tcttctactc cttctatcga atgatttttc
    10261 cagagccgca tgctaaaaat tgtgcgactt cttcttgact aaattggttg cagtccccat
    10321 ggatcgtatg cttcaaggca gaagctgccg tagcaaaatc aatgatttct tgcggagaca
    10381 tattggataa aatcccatgg agcacgccac ctgcaaaagc atctccgcca cctactcgat
    10441 ccacgattgg ggtgattcta tggacttggg attccacata ttcatggttc atccacaatg
    10501 tccccttcaa ttcattttca cttgctgaat gaacggtacg cttggtcgaa taaaacacct
    10561 gaatattcgg gaacttttcc tgcatttttt gataataata aattagaggt tgttcttctg
    10621 cttctggcgc tttctcgata cctaacaaat aaagagcatc catttttcca gctgagcaga
    10681 tatctactaa aggtaaaagc tgatggatta cttcgctggc ttcttgctgt gtccataatt
    10741 ttccacgata gttgatatcg aagctgatca ggcagccagc tttttttgca gcttctatca
    10801 cctgtttcgt cattttttgc cattttttag acaaagctgg ggtgattcct gaaacatgaa
    10861 atatatctat tccttggaat aactcctcta gcgaccattc caaatgatcc atttcagcaa
    10921 aacttgatcc ggcacgatca tagatcactg aggcggcgcg ttcgccacta ccagtttcca
    10981 tataataagt acctagtctt gatccaccag ataatacctg tttcgtatct actccataac
    11041 attgcaagtg ctttttgact gcttttccca atgcgttatc aggtactttt gtagcaaaaa
    11101 tcgcttcatg tccgtaatta gctaaagaaa ttgctacgtt tgcttcccct ccgccataat
    11161 gggcagcgaa tcgttcactt gaatcgatac gggttccctg ctctgtggac aatcgcaaca
    11221 tgatttctcc gagtgtcact acttttccca taagcagcta cctcttgatt tctttcattt
    11281 ttgctgcata ctgttgcgcg acttccgtta ctttgtcaaa atctcctgta gctgcgggtg
    11341 ctaaaaggtt cccacctact ccgactgtta cgacaccagc atcgaaccac tctttcatat
    11401 tgtccagact cacaccgcca gttggcatga tattgacttg aggcatcggc gccttgaagg
    11461 cagaaatgat acttggtcca taagcgcttc caggaaatag tttgacgata tctaccccgc
    11521 ttttcagcgc tgttttgatc tcggtaatag tcatacatcc tggtaagtaa ggaatttgat
    11581 acagattgca catctctgcc gtttcttgat caaaggaagg gctaacaata tactctgcgc
    11641 cagctaagat agccaagcga gctgtgacag cgtctaatac tgtgcctgcg ccaatcacta
    11701 tttctggttg gtctttgtag aatgacaaaa gttctttgat tacttgatct gcttgaggga
    11761 ctgtaaaagt caactcaata ccagttagac cacctttgat gattgcgtgg caagcattca
    11821 aagcttcttc tttgcttttt ccgcgtacca ccgcaatcac tccggcgttt ttcaatcgag
    11881 ataaaatatc aatttttttc atcttctcca cctatttcct atttagaaat tttattttat
    11941 aacttggaaa tctataccca tattatacgg cagaaaagaa aaattgcaaa cgcttttttc
    12001 attatttttg aattctttgc tcgatttcgc tttttgtttg cttgagggca ctgattattt
    12061 gttcttttgt ctcatctgtt aaacgatatt tcggcatact tacactaaat gcaccaatga
    12121 tttgttcgtt tttcacgatt gaggctccta tacaaaaaat atcacgttcg atttcttcat
    12181 cgtcaaatgc gatgtgggtt tcttttaccg ttttgatttc ctttttcaac cgtaatgcat
    12241 tggtgatcgt atattctgtg taagggatca acggatgctt ttcaagataa tcagtgtact
    12301 gctcttcact gaattctgct aatacggctt tgcccatcgc agaattgtat aatggtcggg
    12361 tgattccgat ttttgaagac atgcggatcg tttgatgttt tggatctagt ttgttcacgt
    12421 acaagatctc attgttgtcc aataccccta agtggatagt ctcatcgatc ttttgctgca
    12481 gctgttctaa aaacggtaaa gtcaactcta ccaaatcgat ttgttcaatg tttttattcg
    12541 cgtagcgaat aagctttgca cctaaacgat agtttttctc tgaattttta tttacgtagc
    12601 cgatcatcaa caaagtatct agtattttca agactgtaga agaggtcatt cccacaccct
    12661 ttgcgatcgt ctgcaaagag acatcttggt tttccgctaa atagtctagt attttagagg
    12721 ctttgatcaa tacagttcca taaggctttt tattttccat ataatattct cctatttctt
    12781 tataagaaaa attatagcgg aaataccatc aatttaaaag agatatccag atataaacta
    12841 ccatttctct ttacaggcaa tttaatgttg aagatccgct tcgtttttac atcaaacttt
    12901 gatataaagc aatgatttct tctactgtcg tttctcttgg atttcctggt gtgcatacat
    12961 ctcgcaaagc atcttctgca attgctggaa tatctgcttc ttttacacct aattcagaaa
    13021 tggtttctgg gattccaacc gctttgctca accgatcgat ctcaccacaa gccgcttctc
    13081 ttacatcttc taaagacatt tcagctgctc ctttaatccc tagaacaaga gcgatctcac
    13141 ggtacttttc tccagtatat tctttgttat atttcatgac agttggcaaa agtgctgcac
    13201 acgctacgcc atgaggaatg ttgtaccatg cacttaacgg gtgagccatc ccgtgtacca
    13261 gtcctaaacc gacatttgag aagcccattc ccgcaatata ctgtcctaat gccatttttt
    13321 ctcgcccatt ttgatcgcca tctacagaag cttccaaaga atggccgatg atttcgattg
    13381 cttttaaatg cagcatatca gtcatttccc aagcgccttt tgtgataaac ccttcaatag
    13441 catgcgtcat agcatccata cctgttgatg cagccaattt tttcggcatt cccatcatca
    13501 tatcgctgtc gatgaacgcg acgattggga tatcatgagg atcaacacaa acaaattttc
    13561 ggtgatttac ttcatctgtg atgacgtagt tgatcgttac ttctgctgct gttccagaag
    13621 tcgttggtat agctaatata ggtaaacatg gatttttcgt atcagcaaca ccttctaaac
    13681 taatgacgtc tgaaaactct ggattcgtca aaataatccc aatggctttt gccgtatcga
    13741 ttggcgaacc tccaccgatt gcgatcaaac agtctgcctc tgcctcttta acaaaagcca
    13801 ctccatcttt tacattttgg atcgttggat taggtacgat cccgtcgtat aaagcataag
    13861 cgattgctgc tttatctaga agttctgtta cttttgttgc tataccgtgc tcgatcaatc
    13921 ctttgtcagt aatgacagct gctttgccga atcctcgctg ctgaaattca gggacgatcg
    13981 actcaatcgc tccttttcca aaatacgatg tttcatttaa aatcattcga ttactcattt
    14041 tctattcctc ctaatttgta ttatttttca caataaaaac gaaagaaccc caagcaaccg
    14101 gttgcccagt tgcttgttgc tacagttcaa agactggcat caattcccaa ctgactggag
    14161 aggcatctgg atttgtctcc atgatatctt ccatgtactt ccaccatttt tgattgatag
    14221 atgtatttgc cattttttcc cataactttt catcttcgat cactaagtaa ccaaataaca
    14281 aacttgtact cggatcaaga tagatcgaat agtcgatgac cccgtgttca cgaagtgctg
    14341 tacgcatttc tggccaaagt tcatcatgtc tttttttgta ttcttcttgt ttttctgggt
    14401 aaactttcat gcaaaaagct tttttcacca tgtcagacac ctgctttcgt atgaacttcc
    14461 tccaaataac ctgcttttgg agtgacacca aacgcatctg ctaaatgcca caggttttcg
    14521 tccgtgattg tttgcaagat tggtccttgc gctttgacgt acgtatagac ttctgctgcc
    14581 ttttctgctg tctcgatcaa accaaagact tcatccatgt cttttcctga cccgtagatt
    14641 ccatgttgtg gccataaaac caatcgagtt tctttcattt tttcagctgt tgcttcccca
    14701 atctcatttg ttcccggaac catccacgga atgatggaaa ttccttctgg aaaaacaact
    14761 aagcattccg tacacatttg ccatagcgta cgactaaagg aacgttcgtc taattcatgc
    14821 gtaaaactca tcgctaatag atgactagca tggcaatgca taacgatccg attatctggg
    14881 tctacttcta aacgggcgat atgactcatg aaatgacttg gcaactcgct tgtaggaagg
    14941 cattcgtttt ccagccccca caaaagttcc agtgttttgc catcttcagc aactcgaacg
    15001 attccaagat tctcggcagg ttcgctcgct acatttttaa aatatcttcc tgaaccagtt
    15061 acaataaaat agcatcctgc taaacggctg gcatcaaaaa tcatcgagat gcggcggatc
    15121 actttttcag gatccaagaa cggtgtgatc tcttcttctt ttagtaaata agaaatattc
    15181 ccgccatttc tttcatccca tcccaagcga taaagattcg acgtcgtttc gatcatttct
    15241 ttcacataag gcgcttgtaa aatatctatt tttttcaata tagccacact cctattttct
    15301 taattccaac acgtcttttt gatattcctg gacttcttcc agccaatcca aaccaactgg
    15361 aacttgattt ttgtaacaga aataattcca tacatcggca tacgggaaat ctttcaattc
    15421 ttccgtataa gccattcttg aagtaaagtc aaaagccagc tccatttctt tcaatcgctc
    15481 aactggttcc agcatagctt tcagcagtgc tttttgtgta tttctcgtac cgatgaccca
    15541 agcagcgata cggttgatcg ttgcatcaaa gaaatccaga ccgatatttg ttttttccaa
    15601 caattcgtta cggactaatt ctttagcgat ttcctgcaat tcatcatcca tcaaaaccac
    15661 atggtctgaa tcccaacgca ctggacggga aacatgcaac atgattcctt tgctgaataa
    15721 agctaatgaa gataatttat tggaaatcac ttctgttgga tgaaaatgtc cagcatctag
    15781 acaaacaagt ttgtcacgag tcaacccgta acccatataa aattcatggg aaccgactgt
    15841 ataagcttca gcgcctaaac caaatagttt gctttctact gcatcttgta cataccgttc
    15901 atctaactct tctgtaaaaa tttcatcgag tgattccatt aaacgttccc gtggggtaaa
    15961 acgatcaatc ggattatctt tcatcccatc aggtacccaa aagttattga tacttgtttg
    16021 cccagtttct ttcccaaagt actccgcgat tttgcggctt cttttcccgt gttcgatcca
    16081 gtattcacga acttctttat ctggatgagc caatgtaaag ccgtctttca tcattggatg
    16141 cgaaaagaaa gtcggattga agtcaagacc gatttcttct ttttttgccc actctaccca
    16201 tttttcaaaa tgtttcggct caatttcatt tagatcgaca gattcttctg tatccaaata
    16261 gatagcatga aggttcaatt tgtgtttgcc cggtatcaac gaataagcct tctccagatc
    16321 ttgtctaagc tcttcaggtg ttcgtgcggc tcctggaaaa ttccctgtcg ccatgattcc
    16381 accggtcaat tcgccatccg gtgtcaagaa acctttgaca tcatctcctt gccagcaatg
    16441 catagaaatt ttgatgtcct gtatcttttc tagtacagca tctgtatcta caccgatagt
    16501 tgcatatttt tcttttgctt gttcgtaatt tctttcaatc gtgttcatac gattactcct
    16561 ttgattttat tcacgtacca ttccatcgtg ttttgcttat tttcatctgg gtaaaaagtt
    16621 tcacatggaa acgactgttt gattacattt cttgcttgtt ctatattcga aaactgacct
    16681 gtactgagca tttgcatggc aacattcccg attgctgtgg cttcactagg tcctgcttct
    16741 acaatgattc cggcataatc tgctgtcaat tgattcagta gacgattatt cgatccgccc
    16801 cctacgatgt gcagcttttc caatttcgtt ccagttaagt gttctacttt gatcagctct
    16861 tgtgcgtaac aaagagcaag attatcatac acacaacgag cgatagctcc cgatgagaca
    16921 gggactggct gctctgtttc aaaacagtat tgctgaatct cttctatcat atttggggga
    16981 ttcaaaaatc gagggtcatt gatttccatc acttgctgca gcggtttttc ttttgcagca
    17041 agctctgcca attccgcata actgtactcg tactcttgca ttcgggcaac ttcctggatc
    17101 aaccacatcc ccatgatgtt tttcaaaaaa cgcaccgtgt tatgggcacc ccattcattc
    17161 gtataatttt cagaaaaagc attgcgagaa acattggcga tctttgtttc aatccctaaa
    17221 agcgaccatg tcccactgct gatataaccc caacgttctc cttgacctgg cgttcctaat
    17281 acagctgacg ccgtatcatg acttgctact gtgataaagg tcacatctgg caaatcatat
    17341 tttgaaaatt gttctttttg cagatctcct agtatcgttc ccggctctgt caatggtgga
    17401 aataattcct tcgagacacc gattttttca agaagttcta tttcccattc ttttgtccct
    17461 gcattcagca gctgcatagt agatgcatta gttttctccg tcaccatgtt accagtaaag
    17521 acatacccta aataatcagg tatcagtaac aatttatgtg cttttgccaa attttctttt
    17581 tcttcagcaa acaattggaa caaggtattg aaaggctgga tctgaatccc tgtctgctca
    17641 tacaacttat ctagagaata gatttcagaa aactgttcta ctgctccatt ggtacgcttg
    17701 tcccgataag caatcggatc atttatccga tccccttgtt catcaatcag acagtaatcg
    17761 actgcccatg tatcgatccc cgcaaaaagg cgatcaatcc ctgtctgctt taatttttca
    17821 aatccaatca aaatctcttt gataagataa tcgatcttcc agcgatcgtg accgtctttg
    17881 ttccgaaagc cgtttttgaa ccggtgtact tcttccaaga tcaaagaacc ttttgcatcc
    17941 ctcgtacttt tcattagtcg tccgcttgat gcaccgatat cgatggcaac aaatgttgga
    18001 ttcatttctc cacctctttt actttattgt tgattagcac tttattaata aagcgttatc
    18061 atttattgac aatgctatca taatacagaa tcttatattt tgcttcacac tattttggta
    18121 tataattgca ttatcttgac aagttgggag tgtttacatg gattactggg aaaaagccaa
    18181 ccactcatgg tcggaagact caaaaagagt gatcttgacg cctacacaaa gaagcaggaa
    18241 tttatttttt tatatccaag aaatcggtta cttcaaagca ccaatccctt actatactga
    18301 acgagcacat ttaccttctt acttgataaa gtttactttg tctggcaaag gttcgcttac
    18361 atataatgat aatcagcaac agctaaaagc tggagactta ttttttattg actgccaaga
    18421 atatcagcgt tatcaaacga tcagcgaaga accatgggaa atggattgga tccatttgaa
    18481 tggtcagaac gtccaatcat tttatcagga gttcacaaaa gacggccata acaccttcca
    18541 ttcaacagga gatccatcag aaaacaagat ccaccatttg atcacagaat tgatccacat
    18601 gcaacaaggc acgaatgccc gtaccgattt ccagtcctct gtagctatcc acgagttgct
    18661 gaatgaactg attttgcaaa agtatcagct agatttcgaa gaagaggata ttcccgccta
    18721 cgtttacaaa ctgaagcaat acttagacga acatttcaaa gaaacgatta cacttgatca
    18781 attagaacaa caattcttat tgaataaata tcagctgagc aaagattttt ccaaatttat
    18841 cggttctcca ccaatcgatt atttgatcag caaaaaactt tcttacgcta aagaccttct
    18901 tcggtataca gaatttacgg ttcgaatgat ttccgaagaa atagggattg agaattttgc
    18961 ttactttagc cgcctgttca aagcaaaaac aggactatcg ccgagagact ttcgtaaatt
    19021 cagctgattc atataatatg tacgtcattt tttcaaaata ttttgaaata tatagataaa
    19081 aataaaataa ccgcagtttc tgcttctatg taaacaacag cagctactgc ggttattttt
    19141 tagtgatcat tctcattgtt catcttcaaa atgttcataa tgaaccaact gtttctgtgt
    19201 atcacgtttc aaaaattctt taggcgttat gccgaactct ctcttgaatg ctttcagaaa
    19261 atgcggataa gaagaaaaac cacttttact atatacagca ctagagctgc ggtattctcg
    19321 caacaagtgc ttggcataga tcagcttttt cttcattaca tactgatgaa acgtaaatcc
    19381 agtgtacttt ttaaattctc gtgtgatatg gtatttgctg acaaaaaact gcttttccat
    19441 ttcctctaaa gaaagcggat gagataaatt ttttgagata tattgtaaca tttgttccac
    19501 acgctcatta ggaactacag cattctgttc ttgcgcactc tcttcttttt gtacaacttg
    19561 attgagaaaa atcaagtatt ctaccagagc ttgttcatat tttatgtctt caccgtaaat
    19621 ttttttatca ggaggatggt cgataaatga taatttttgc ttcaatactt cctgttctat
    19681 ttgcaataca cgactcctct tctctcccat tggttgaaaa caagccgata gattagacca
    19741 tggcgtggaa cgactttcta gaaaagaagg ggtgacaaag atatagacac gctcgaatac
    19801 atctgaagat tggcggacga tacgatgcaa atcattggaa tggatgagca gcacacttcc
    19861 tgctttgatc gtaaattgtc gtccgttcaa ataaaaagtc gcttctccct ttaatgtagc
    19921 atggatctca tagaaatcat gatgatgata gatcgtttta ttttggctga cgacatcttt
    19981 gacatgatag atttcatact gatcagaaac catcgtattg acttgttcac cgctgatttt
    20041 cttttggagc atgtgccgca cctccttttg ttcacttatg cacaatttta ttataccacg
    20101 ttttttgtaa tcaaaaagag ctgcttttat atactcttat aaaaaagaag agacgtggca
    20161 tcttctagcc ccgccccctc cattctaaat attagttaac caacgtcttc tttacattat
    20221 tcaagaagac ttcttccata acgaatccca tcatcttttg tttcttcaag aaccacatac
    20281 aggtacggac gattcttcat gatgatttct ttgatttttg tgtactcgat cacaccgtct
    20341 cccaaattta ccggcacgat tttttcctgt tcgacacgaa aatctttcaa atgaaccgca
    20401 catatctttt caccaaaacg ttcaaaagct tcttctacca attggacttg ttcttgataa
    20461 tcactacttg tgatcaaatt ggtcggatct aaaatgattc ctagatagtc cgaatctact
    20521 gcttggatca gctgctctac ccttgctaaa gaatacaccg gatgattcaa acctggttct
    20581 atccccacca tcatttggta tttttctcca gcttttacca agcgacggat aacggacaca
    20641 gcttcagcaa atgcttcatc tgtgaaattt tcttccgtat attggatttc cggcaaaaca
    20701 catccagttt ccgaagcaac catcgacgca ccaaaggaag aagcatagcg aagatactgc
    20761 tcgaactttg tcagcaactc ttgtcgtatc gttaaatctg gatgaatcat attgatatag
    20821 caacttaaaa ttcctacggt cacttcttgc ttttctaaaa ctcgtttgac ataatttccc
    20881 atcccagaat tgatctcatt tgcgccagaa ggtatttcag gaaacgaaag acctaaggcg
    20941 agctgcagtg tatgaatccc ttgttctttt gttttttctg caagatcttc tatcgtttgg
    21001 acttcggaaa gatcatgtcc tctaattgta atgttcaaca taactattct cctaactcag
    21061 catattgggt agccacatga cgatttgcgg gaagtaagta atcaaaaaca agacgactaa
    21121 gataacccca taaaaaggaa gaagcggttt cagcattgcc tctgctttta cgcctcctac
    21181 acttgcaccg acatatagtc ctgtacctac tggcggcgtg atggagccta cacacagatt
    21241 catgattgaa aacaacccgt aatgtacagg atcaacccct acacttgtga cgattggtaa
    21301 aaatattggt gtaaaaatca agatagcagg cgccacatcc ataaacatac ccaccagtaa
    21361 taacacaaga ttgactaata acagaataat aaatttatta tccgttacgc ccataatcaa
    21421 cgaactaatt gcctgaggaa taccggtaaa cgccatggcg aaagacatca tggaagaagt
    21481 agccaataag aacatgatcg tccctgacat tgctactgat tgaaacaaca tattaggtat
    21541 atcttttagt tttaccgttt tatagtaaaa catagcaatc aacagggagt aaatgacagc
    21601 tatcgctgaa gcttctactg ctgtaaatat ccccgtcaag ataccaccga taatgatgac
    21661 aatcaataga aggctaggaa tcgcctcttt tattattttt ccagcatgag ccatctgtcc
    21721 tttttcgaca acagggtatt tattcttttt agcaacgatg aatgctacta gcatgattcc
    21781 tagcgcccac aaagcgccta cgagataacc tcccataaac aaagcagaga tcgaagcacc
    21841 accagcaaca agtgaataca tgataaaagc agtacttgga ggaatgacca tacctgtcgg
    21901 agctgacgcg atattgaccg ctgtcgcaaa cttccggtca tatccttctt ccacttgctg
    21961 agggatcaac actccgccaa tcgcggtaga agcggcaatg gccgagctag agatggaacc
    22021 aaataaagca ttccctaaca cattcgtatg agccaaagcc cccggcacgc gcccgacgaa
    22081 caacatcgca aaatccacta gtttcttagc tatccctcca ttattcatga taatgcccga
    22141 gagaacgaaa aacggaatag cgatcagcga aaaactattg atacttccca ccattttttg
    22201 agctgaacta aaagcagaaa catcaaacgg tataactaac aataaagtca tcatcgatga
    22261 gaatgcaata cttatagcaa tcggcatccc taatacaagc aacacaacaa atacaaaaaa
    22321 taacactaat ccggcttcta ttgccatttt attcctccat ttttatattt tttcttgaat
    22381 tgctggcttg ttgcttaatg tatcgattag attgatcagg ctatagataa tgatgagtac
    22441 ccccgataca ggtactgaca gataaacata tcccatagga atacttaaag aaggcgagat
    22501 ctgccccatt gtcaatgtga cagcattcca tccgccatac accatgatca tcgcagcaaa
    22561 taccagaaat aaactttgaa caacaacttc taaaatttta ctttttttgc cagttaattt
    22621 ttcacttaaa accgttacgg ctaaatgtgc tttttgtccc acaacatacg cggaagacaa
    22681 catggcaaac cagacaagac cgaatcgaac aagctcttcc gtgaccgtat ttggatttcc
    22741 taaaaccgtt ctggaaaata cttgccataa aacaacagcg accatcccaa caagcaaaac
    22801 agctcccagg atctctaata ccttgtttaa aatcattttc atcacagcta cgctccttgc
    22861 tcttggatct tttgataaag gtctttgtag gtaggatcgt ttttgaatat atcatgaagt
    22921 ggggcaactg cctctcgaaa cggtgtatta tctacatcat tgaattggac tccatgttct
    22981 tcttgtgcta aagctttttc ttcttcaatt gcttttgcaa aagcttcaat ttcaaaaacc
    23041 gttgattctt tcgctgcttc ttcaatggct ttttcctgct catcagttag ctgttctttg
    23101 atggcatcat tcatgatgat gatatctggc acacgtgtat gctcatcata ggaatagtat
    23161 ttagccacac caccatgtcc agctgtatac aagacaaatt cattgttttc tgatccgttg
    23221 atcaaattgg attgaagaga cgtgtacact tcatcacttc ccataggtac gggcgaaccg
    23281 cctaaaagct ctaccatttt gatagcggtt tcgctttgca tcacacggat cttctttccc
    23341 ttcaaatctt ccggcgtatg gatcggaccg tctaccatat aaaagctgcg ctgaccagaa
    23401 tcataatagg tcaatccggt aaatcctaaa tttttggtcg attggtagat tggctccatt
    23461 atttcttcat tatccatcac cttaaagaaa tgttcttcat cattgaatag ataaggaact
    23521 gaaaaaatcg aataatcttt agagaaactt tccaacgctg aggcacttac ttttgtgaaa
    23581 tctactgctc ctgactgtgt caattcgatc agttcacgtt ctccacccag ttgtccatct
    23641 gggaaatact ggatctgtac ggaaccatct gttttttctt ttactaaacg cccaaattca
    23701 ttcattgcat caattactgg ctggctgttg cttgcataag caaagcgcaa ggtaactatc
    23761 tcatttacat ctgcatctgc gacagttgcc acactagaat tatttccgca gccgcttaga
    23821 cctagcagac ctaggctaag cgaacttgct gcaaacagca gtgatgtttt tttcatatgg
    23881 gtttcctttc ttttaacaat aagagacgag caattctgtc aaacaaagca ccgttaacga
    23941 ctgtccataa ggcattgctg tgattccgat attccgataa aaatctaaac tgtcccccat
    24001 tcctgtcccg attgaaacgt tttgaacttc tcctttttca tcgatttgtt caagcaatcc
    24061 ttggatagca cgataagcga cttctttata ttcttgtggt aaataacgtt tatggaccgc
    24121 tttcaaaata ccgtaagcaa atcctgcagt tgcagaagat tctacgtaag aagaaggatc
    24181 atccaacaac gtatgccata aaccgctttc agactgataa gtttttaatg cacgcacttg
    24241 tgcttcaagt gtttcgatca ataatttgcg caatgcatct tctttcgata attctaagat
    24301 ttcaatgatc tctggaatag caatcgtcaa ccagcagttt ccacgagccc aaaatgcttc
    24361 ggcatagtta tgatttcctt caaacgtcca gccgtgatac cacaatcctg ttcgtttatc
    24421 catcaagtat ttgatatgga tcataaactg gtaacgagct tcttctaaat attctgggcg
    24481 attcaacagt ttcccgattt ttgccaaagg aagcactgtc atcatcaatg tatcgtccca
    24541 caactgattc ttattttccg gtccatatgt ggcatgctgt aacccgtctt catttgtccg
    24601 aggcatgtca ttcatgaccc attctgccca ttgttctaaa taaggcaaat agcgtgaatc
    24661 tttcgtgtct tcatacaagt aagccatagt caatagcggt gccattgtat tgacgttttt
    24721 gggcggagcg ccttcttcca tacgatcctc aaaccattca ttgaccactt gataagcgcg
    24781 aggatttttt gtcatctggt aatttttata aataccatat agaccgacac cttgtggcca
    24841 attccacact gtccagcttt tgtcatctac tttcagtcca tcaaagtcca acaaaaattc
    24901 accattatcg tctttgatcg ttgtcaggtt ttcaacgagc aggtcaattt tttctttcac
    24961 taattcttta ggtacaaaaa tctcttcttt aataatcatc tttacgccac ctttttaaac
    25021 gctttcattt tatatcctta atatagcagt aataccgtcc actataaata tcgctttttg
    25081 aacaaaaact gtctaaaatt gacctaaatg ttaaataaca aaagtaactt tcagttactt
    25141 ggaaattaaa aaaagaactt ggagaaacaa cgttttccaa gttctttttc atctattttc
    25201 ttatcttttt tctacgcttt cttttgctta tccgttgtaa gcatcaatga tgatctgttt
    25261 caattcagag atcaatggtt ctttcggatt agctgtcgta cattggtctt cgtaagctaa
    25321 ttcagccata cggtctacgg ttgtatctag tgtttcttgt gtgactcctt gagcttttag
    25381 actcatgttg atgccgacag attttcctaa ttcataaaca gccgttgcta aagcttcgac
    25441 taattcctct gttgtttcgc ctttcagacc taagaatttt gcgatatctg cgtaatctgt
    25501 atctgcacgg aaatagtcat atttagggaa catcgcatgt ttttgtggat cttttgcatt
    25561 atagcggata atatgcggta aaagaatcgc atttgtccgt ccatgaggga tcccgtattc
    25621 cccgccgatt ttatgtgcga ctgagtgaca aatacctagg aatgcgttag caaacgccat
    25681 accagccatt gtagaagcgt tgtgcatttt ttcacgtgat tccatatcag gtgtttttac
    25741 tgatttttct aaatagtcaa agactaactt gattgcttgt aggctcaatc cacgtgtata
    25801 atctgaagcc atgactgaaa cataggattc gattgcatgt gttaacacat ccatcccggt
    25861 atctgctgtg acagatgctg gaactgacat gacgaattga ggatcgacga ttgcgacatc
    25921 tggcgtcaat gcataatctg ctaacggata tttcacatgt gtttcactgt cagtgatgac
    25981 cgcaaatggc gttacttcag aaccagtccc tgatgttgtc gggatacata cgaattgtgt
    26041 tttttctggt ttgtcgatct tatatgtccg tttacggata tccaagaatt tttgttttgc
    26101 accaaagaaa gatgtgtctg ggtgttcata gaacatccac attcccttag ctgcgtccat
    26161 tgcagaaccg cctccaagag cgattactgt atctggcttg aagtctgcca tcagtttcgt
    26221 tcctgcgtat acggtatttg tcgatgggtt cggttcaaca tctgagaaga cttcgatctt
    26281 cacatcattt ttacgtcgtg ccaatacttc acgaactgta tcgcagtaac cgaattggac
    26341 cataccaggg tcacaaacga tcatgacacg ttcaacgttt tccattttct ctaagtacaa
    26401 tagagagttc ttttcaaaga agatttttgg cggtaatttg aaccattgca tgttatttct
    26461 ccgtttcgct acagttttga cattgattaa gtttacagca gagacgttac gagaaacaga
    26521 gttcttacca taagaaccgc atcccaaagt caatgacgga atcatttcgt tatagatatc
    26581 accgatgccg ccttctgcag atggtgtatt cactaaaata cgacaagctt tcattcgaag
    26641 accgaatttg acatgcaact cttcgttttc tgaatggata actgctgtat gtcctaatcc
    26701 tccaagattc aacatacctt cacacaaatc aaacgcatgg tccgtgttgt tagctttgat
    26761 catggcaaga actggagaaa gtttttctct tgatagcgga taatctgggc ctacgccttc
    26821 caattcagca atcagcattt tcgttccttt tggtacactg attcctgcca attttgcgat
    26881 ttccatcgca gaatgtccaa cgattgatgg attgaccgca tattttcctt cgttcatcac
    26941 tgcatcttct aatttttgca attcatctgg ttttacgata taaacttggt gtgcttggaa
    27001 ttctgctttt actgctgcat agatttcttt atccacgatc acagcttgtt cagaagcaca
    27061 aatcattcca ttatcaaatg ttttcgaaac gatcaaatcg ttcactgcac gtttaatttt
    27121 tgctgttttt tcaatataag ctggtacgtt acctggacct acacctaaag ctggttttcc
    27181 tgtagagtaa gcagacttga ccattccagc tccacctgtc gctaagacga tcgcgatacc
    27241 tggatggttc attagcatag aagtcgcttc gatcgaagga tgttcgatcc attggataca
    27301 attttcagga gctccggcag cgatagcagc atcacgtacc actcgtgctg cttctgcaga
    27361 agatttttgg gcacttggat ggaaagcaaa aacgattgga tttcttgttt tcaacgcgat
    27421 cattgatttg aaaatcgttg tggaagtcgg attcgttgtt ggagttactc cgcaaaccac
    27481 accgactggt tcagcaattt caatcaaccc tttttggaca tcttcattga tcacaccaac
    27541 tgttttatca tgtttgatat tatgccaaat atattcggac gcatacatat ttttgattgc
    27601 tttatcttcg taaacaccgc ggcctgtttc ctctacagcc atcttcgcta atggcatatg
    27661 ttgatccaaa gctgccattg ccatttcatg cacgatatgg tctacttttt cttgatcaaa
    27721 gctttccatt tctttcaatg ctgcatttgc tttttctgcc aaatcatcaa tcattgcttg
    27781 tacgtcaatt gtcttcgttt tttctttttc tattacttta gccatcatta tcctcctaat
    27841 gggtcatggt tatttgttaa ataattcaca tgtatatcat acaatattta tttttctatg
    27901 taaacacttt tttgtgattt ttttcacagt tatttttaaa tataaaattg ctttatttac
    27961 aggtgtttgt atagaaaaat atataaagtt atttattatt atttatatga cacacccgat
    28021 tattcaatat tgagcaatat atcccatgct cttatctctt tcttttttga ataaaaaatg
    28081 aggtaggaca tctttctgcc ctacctcgtc tttaaataag ctttgatact tatttttctt
    28141 ccttctcttc tgtctcttcc agcgtttctg ttgtttcagt ttttacttca actgtctcag
    28201 ctggttcttc tgttgtttca acagtagtcg ttgcatcatt tgttacgaca gtccctggtt
    28261 tgaccgtttt gattgctgca cgatcgtact caaggaagat cccttcgcag tctaaaacaa
    28321 ctgtccgttt gtcattgtcg atttctgaaa caactccatg taatccgccg atcgttacga
    28381 ctgaatcacc tggtttcatg ctatctaaca agttttgacg ttcttgctgt tgtttctttt
    28441 gcgaacgtga cataaaaaac cacattgcta atagcgcgat aaacatcaca agcattggta
    28501 atgttcccat ttttttcacc tcactaattc tgtatctaca aaaaacactt tagcagaaaa
    28561 atgctgataa cactagtttt ttacttaatt tttaaaagat tttcctttag aagctttttg
    28621 cgttttcttt attgaacccg tattcttcaa aaaaggcttc tctaaattca agcaaattat
    28681 catccatgat tgcttgacgt acttgtttca ttagattcaa caagaagtat aaattgtggt
    28741 aagaagtcaa acgaatccca aatgtttcat cacatttgat caaatggcgg atataggcac
    28801 gtgtatagtt tttacatgta taacaatcac atttctcatc aattggacgg aaatcatggg
    28861 catatttcgc atttttcact actagacggc cttgagaagt catacatgtg ccatttcgag
    28921 cgattcgagt aggcaagaca cagtcaaaca tgtctactcc acggataaca ccatcgatca
    28981 atgaatcagc agcaccgaca cccatcaagt aacgtggttt gttttcgggg atcaacggtg
    29041 tagtgaattc taatacacga ttcatttctg atttaggttc cccgacagat aacccgccga
    29101 ttgagtaacc agggaaatcc atcccgacta gatctttcgc gctttgacga cgaagatctt
    29161 caaaccctgc tccttggatg attccaaata atccttgacg gtctggatta gcatgagctt
    29221 tcaatcctcg ttctgcccat cgagacgtac gttctactga ttttttcacg tagtcgtaac
    29281 tttcatcgaa tggtggacat tcgtcaaaac tcatcatgat atcagagccc aatttatttt
    29341 ggatgttgat tgctttttct ggtgataaaa acatacgcga accgttcaag tgatttttga
    29401 aatgcacgcc ttcttcttcg atattccgca tatcacttaa tgaaaaaact tgaaagccgc
    29461 ctgaatctgt taaaatcggt tgatcccagt tcataaattt atgcagtccg ccagcttctt
    29521 ctactaagtc ttcaccaggg cgtagccata aatgatatgt attacttaaa ataacgccag
    29581 cacccatttc tttcaactct tctggggaca ttgtttttac tgtagctaat gttcctactg
    29641 gcatgaacat tggtgtgggg aaagtt
//
LOCUS       DAFTHM010000026        29189 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFTHM010000026 DAFTHM010000000
VERSION     DAFTHM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.026"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            288..695
                     /locus_tag="L7C88_001155"
     CDS             288..695
                     /locus_tag="L7C88_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558000.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            709..1110
                     /locus_tag="L7C88_001156"
     CDS             709..1110
                     /locus_tag="L7C88_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558001.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1112..1483
                     /locus_tag="L7C88_001157"
     CDS             1112..1483
                     /locus_tag="L7C88_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558002.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1519..1821)
                     /locus_tag="L7C88_001158"
     CDS             complement(1519..1821)
                     /locus_tag="L7C88_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558003.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2070..2270)
                     /locus_tag="L7C88_001159"
     CDS             complement(2070..2270)
                     /locus_tag="L7C88_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBP9558004.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(2575..3807)
                     /locus_tag="L7C88_001160"
     CDS             complement(2575..3807)
                     /locus_tag="L7C88_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBP9558005.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            4061..4630
                     /locus_tag="L7C88_001161"
     CDS             4061..4630
                     /locus_tag="L7C88_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBP9558006.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4808..5248)
                     /locus_tag="L7C88_001162"
     CDS             complement(4808..5248)
                     /locus_tag="L7C88_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBP9558007.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5406..6170
                     /gene="map"
                     /locus_tag="L7C88_001163"
     CDS             5406..6170
                     /gene="map"
                     /locus_tag="L7C88_001163"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBP9558008.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6202..7125
                     /locus_tag="L7C88_001164"
     CDS             6202..7125
                     /locus_tag="L7C88_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBP9558009.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7201..8340
                     /locus_tag="L7C88_001165"
     CDS             7201..8340
                     /locus_tag="L7C88_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBP9558010.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIVLIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8333..9133
                     /locus_tag="L7C88_001166"
     CDS             8333..9133
                     /locus_tag="L7C88_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBP9558011.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9133..9960
                     /locus_tag="L7C88_001167"
     CDS             9133..9960
                     /locus_tag="L7C88_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBP9558012.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9938..10672
                     /locus_tag="L7C88_001168"
     CDS             9938..10672
                     /locus_tag="L7C88_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBP9558013.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            10772..11638
                     /gene="rfbA"
                     /locus_tag="L7C88_001169"
     CDS             10772..11638
                     /gene="rfbA"
                     /locus_tag="L7C88_001169"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBP9558014.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11652..12224
                     /gene="rfbC"
                     /locus_tag="L7C88_001170"
     CDS             11652..12224
                     /gene="rfbC"
                     /locus_tag="L7C88_001170"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBP9558015.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12246..13274
                     /gene="rfbB"
                     /locus_tag="L7C88_001171"
     CDS             12246..13274
                     /gene="rfbB"
                     /locus_tag="L7C88_001171"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBP9558016.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13372..14223
                     /gene="rfbD"
                     /locus_tag="L7C88_001172"
     CDS             13372..14223
                     /gene="rfbD"
                     /locus_tag="L7C88_001172"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBP9558017.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14258..16291
                     /locus_tag="L7C88_001173"
     CDS             14258..16291
                     /locus_tag="L7C88_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558018.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16335..17615
                     /locus_tag="L7C88_001174"
     CDS             16335..17615
                     /locus_tag="L7C88_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBP9558019.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LVILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTDREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17825..18631
                     /locus_tag="L7C88_001175"
     CDS             17825..18631
                     /locus_tag="L7C88_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9558020.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18643..19863
                     /locus_tag="L7C88_001176"
     CDS             18643..19863
                     /locus_tag="L7C88_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558021.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19853..21439
                     /locus_tag="L7C88_001177"
     CDS             19853..21439
                     /locus_tag="L7C88_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBP9558022.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21478..23616
                     /locus_tag="L7C88_001178"
     CDS             21478..23616
                     /locus_tag="L7C88_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBP9558023.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKDGIGDFSLRPD"
     gene            complement(23984..24967)
                     /locus_tag="L7C88_001179"
     CDS             complement(23984..24967)
                     /locus_tag="L7C88_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBP9558024.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            25345..26736
                     /locus_tag="L7C88_001180"
     CDS             25345..26736
                     /locus_tag="L7C88_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBP9558025.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERSFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            26752..27792
                     /locus_tag="L7C88_001181"
     CDS             26752..27792
                     /locus_tag="L7C88_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBP9558026.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDKAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            27811..28896
                     /locus_tag="L7C88_001182"
     CDS             27811..28896
                     /locus_tag="L7C88_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBP9558027.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            28929..>29189
                     /locus_tag="L7C88_001183"
     CDS             28929..>29189
                     /locus_tag="L7C88_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBP9558028.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKY"
BASE COUNT         9471 a         4790 c         5850 g         9078 t
ORIGIN      
        1 ttgaggggaa gtacatatag ttgttgatat agttgctaat attgttagct aatttgttag
       61 taaaactgta tacgaattta gatagtaaaa aaacagtttg ttccttatat agaggcactt
      121 ttactactga ttaaatgtca gatatgctta caaatatact tataaatatg cttacaaaat
      181 tagctaatat ttccgttgac aaagctttgt tactattgtt aaactaaatt gactagcaaa
      241 agtgaaacat aaatttatta aataaatgta aaaattagga gaaatcaatg tcttatagag
      301 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
      361 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      421 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      481 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      541 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      601 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      661 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      721 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      781 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      841 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      901 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      961 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
     1021 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
     1081 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
     1141 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
     1201 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
     1261 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1321 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1381 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1441 gatgaatcga gaagcagaaa aaataataaa caaactcacc taatgaattt caagcgagtt
     1501 tgtttgttat ttttttattt aatctttgta tctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatgat cgctacgtgc gtccggcacg tcagtcacga tatcaaacaa
     1621 aaagtataca cccttcttca ttctagtttt cgcagcagga attttgaaat agttcttatt
     1681 agaatagtag agattgatta ataagctatc ttcgattgct aaaaagaaaa cttctgaatt
     1741 ccatacttta taaaaatctt tgataaatct attcgaaggg tcaaatttaa accataattg
     1801 tgtttttcct tccatcagca taaaagttca cctcaaaaag agtatacgaa cgaatgttct
     1861 ttttgtgaag gcggaattta atatactgaa taatagaaaa caagtacttg tgccaaatta
     1921 tgtgccaaaa aaattcgaat tcaacaaaat gtaaacaaat agaaaacctt ctatattaag
     1981 atttcctgca ataacaaaca caacagaaga cgtgtaatag ttagtcagga acgtacaaat
     2041 aacccctgta tcctttgcgg tacagggggt tattttgtat aagtagacat tgtagtttct
     2101 aaactgctat gtcctaaacg tttcgatacg ctaagtatat ttactccttg ataaagtaaa
     2161 atagatgcat gcgtatgtct tagtccatca ataaacagtc gaagagaaaa tagggaaaaa
     2221 ttgattacta aagaaaaact tactaggtcg acggtgtagt tgattttcat acttcaatag
     2281 attcgaatta aacgatttcg attggcttat accagtccta tccaacgaaa gatatatcgt
     2341 tcttaactct agcggtataa cttgaagctt tacgtaaagc caatgggaat gaactggaga
     2401 tgacttttta ttatttttag taatagctga tgggttaata cttacaactt tccttttcaa
     2461 agtaccatat aaaaaaacgg tggggttgtt tagcgaaata aaggatctaa gccaatagct
     2521 tagatccttt attctatgct ttatattatt ttttgcatgt gtgcgaaagt atactcaagc
     2581 ccaatcgcca tttcggaaaa tcggtactgt agagccatct tcacggattc cgtcgatatc
     2641 catcttgtca gatcctacca tgaaatctac gtgggtttga cttctattca atccagcttc
     2701 tgctaattct tcatcggaca tttctgtacc gcctttcaca ctgaaggcat aagcagaacc
     2761 tagtgctaag tgattcgatg cgttttcatc aaataatgta ttgaaaaaga tgatgccaga
     2821 ttgagaaata ggtgaagggt caggtacaag tgcgacttct cctaaacgac gcgcaccttc
     2881 atctgtatca agcagttttg ctaagacatc ttctccttgt tcggcagaaa aatcaacaac
     2941 ttttccatct ttaaaagtaa atttcatacc cgagatgatg gtgccagcat aactcagtgg
     3001 ctttgtactt gaaatgtaac catctactcg atgactgtca ggtgctgtga acacttcttc
     3061 cgtcggcata tttgccatga atttttctcc acgagcatta tagcttccag cgccttccca
     3121 aagatggttt ttaggcaatc cgataatgat atctgtaccg ggagcagtat agtgaagggc
     3181 agaaaattgt tctcgattca attcttctgc tttttttgct aatttttcat catgcttctt
     3241 ccatgctaag acagggtctt cttcatagac acgagtcgtt ttgaaaatct gatcccataa
     3301 tgcctcaact tgtttttctt ctggcagttc tgggaagact tttgctgccc attgtttacc
     3361 agccgcagcc acgacagtcc aactgacttt atttgcttga gttgccttgc gtaaattcat
     3421 tagtgctttg ccattcgctg attgataaga cgctactcga tggctatcta caccagcaaa
     3481 tgcatcggga tcggcagaaa caacgctgat cctgcttgct cctttttcaa gccattcatc
     3541 cgcttgatcg attttagatt gtggtacatt ctcaatacga tccgttgcag catgtaaaag
     3601 aaattctctt tggatctggt cgtcagtcca ttgaacgata acctcagcgg ctcctagttt
     3661 ataagcttct tgtgtgatca atcgagcaag gggtgcctgt tccacgctga tctgtaaaac
     3721 aactgtgtgt cctttttctg tggctacgcc agtttctgca attaagcgtg catatttttt
     3781 tagaagttca ttaaaatcag ataacataat aaaaattcct cctcaccatt ttttctggta
     3841 actattagca tgataccatt taattatgat tcaaacaatg aggctttaaa taaaaaaagg
     3901 aggttatttt tttaaggtta agtttcatga tatatgttac tacttgctat ttcagcttgt
     3961 gaagaaaatc aaaaactaat tttgcatatc aaaaaaacat gttacaatga aattaatcaa
     4021 tggtggaagc gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat
     4081 tactagagaa cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg
     4141 atttactgcg agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga
     4201 gtttaaaaat atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca
     4261 atatgaagtg ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta
     4321 tatccatttt gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg
     4381 tggaggaaaa gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga
     4441 tccagcttat gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat
     4501 catagctact gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca
     4561 gattgaaaag atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga
     4621 aatcgattga atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa
     4681 taaggaaaag ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca
     4741 tgaatgcaat gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc
     4801 aagtatatta aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt
     4861 cttcttcagc attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg
     4921 caaaagcagc atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag
     4981 atccgcagac accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt
     5041 ctacgatctc atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat
     5101 ctgcctcctc gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat
     5161 ccagattttc aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc
     5221 tagcatatac gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa
     5281 ttatgaatta taccaaaaca tcattgaaaa gaaaataaaa cctaaagaca cctggggaat
     5341 gtcatttggc taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg
     5401 aaaatatgat tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt
     5461 tattagcaga tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg
     5521 atattgaggt atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg
     5581 gctttgaagg gtatgaatat gcgacttgta tcagtataaa tgatgaaatt tgtcatggat
     5641 tccctcgtaa aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt
     5701 tgaaaggcgg catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga
     5761 tcgaccgatt gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag
     5821 tagggaatcg gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc
     5881 tagcgatcgt tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag
     5941 cagttcctca ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca
     6001 cgatcgaacc tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga
     6061 ctgcgtatac aagagacggc ggactttctt gccaatatga acatacattg gctattacta
     6121 aagatggtcc aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt
     6181 caataggtac gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg
     6241 atgcgcttta ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct
     6301 gtcgtcgttg cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat
     6361 attttaccgt ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt
     6421 cctgagaccg tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca
     6481 ggaggcttgt tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat
     6541 gctttgcaaa ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc
     6601 gtccgtttct tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact
     6661 atcgttcttg ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc
     6721 gtgaacttta tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt
     6781 gtcatcatgt tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc
     6841 attccgggca cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc
     6901 tatgctaggt attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta
     6961 ctcatgcttt ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca
     7021 gttgttcaag aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa
     7081 tggttcaata aattgaaaac taaattttct cataaaaaaa agtagaaaca agagttctta
     7141 ttgtaaattt atatcagtaa tttataataa ttatgactct taattaaagt aggtgctcat
     7201 atgcttgttt cttttagtat ggttataaga ttttttctga caattttatt atcactgata
     7261 ttaacacctg tattcaaaat catttcagta caaacaggta tggtcgacaa accaaatgaa
     7321 agaagaataa ataaagttcc aatgccttca gcgggcggac tgcctatctt tatttcattt
     7381 gttatatcga ctttattctt attccgtaaa attatccctc aatcgtatat tgtaccgatc
     7441 ttgattgctt ctttagtaat catagtcaca ggagtgctcg atgataaata tgagctgaca
     7501 cctaaacaaa aaagtatagg gatcttgatt gcttctctta ttatttattt tgtagcagat
     7561 atacgtattg attccttcac gcttcctttt attggatata tccaactagg ctggcttagt
     7621 tttcccgtaa cgattttttg gatcttcggt atcacgaatg cggtcaatct gattgacggt
     7681 ttggatgggc tggcggcagg gatttcattg atcggtttaa ttacgatagg aatcattgga
     7741 tattttttcc tccatgcttc tacagtgtat attccagttg ttattttctg tcttgtagca
     7801 agtattatcg gtttttttcc ttacaatttt tatccggcaa agatttattt aggcgataca
     7861 ggagctctat tcctagggtt tatgatggcc gtcctttcac tacaagggct gaagaacgtg
     7921 acttttgttt catcgatttc tttgctgatc gtcatgggag tgccggtaac agacacgttt
     7981 tttgctatca ttaggagaaa agcaaaccgt gtttcttttt ctacagcaga taaaaaacat
     8041 cttcatcacc gactaatcag tttaggcttt actcataaag gtgctgtcct gacgatttat
     8101 gcgatggctt tgatgttttc tttcacagct atggtcatga attatactgg aagaatcgga
     8161 acgatcgtat tgattattgc catgttgttt gctgcaattt tattatttga attgattggt
     8221 ctgatcaatg agaaacatca gtttatttta aaaacattgc gatttttagg gaataaagag
     8281 taccgtacgc aagtaaaaca gaaatatttg aagaaatgga accgtcatat agatgaataa
     8341 caaattaaac cagccgatcc ttattagtat tgtgacggca aacagtgata aaatttttcg
     8401 gacactagat aattttattt caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt
     8461 tgacaacaat tcacttcccg agtacaaaaa aagactaaca gagtatagga aatatcccta
     8521 catcgatatc tattttcatg atgaaaattc cggatttggt tatggacata atcacaatct
     8581 gatagctagc gattctcgct atggcattat ttgtaaccca gatattttag tggatgaaga
     8641 gacagttaca gcattggtct tgttattgaa agaacatccg gaatgtgcga tgttagcacc
     8701 taagattctt aatgaagatg gaacaactca gcacctcatc cgtgagcagc tggctgtttt
     8761 tgattacgtt ttgcgctttg tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact
     8821 ggctgtgttt gaatgccgag gattgcctac tgatgctaat agttatgtac ggatgatctc
     8881 aggtagtttt atggtagctg atattgataa atttaaagag ataaaggggt ttgatgagcg
     8941 tttcttcatg tactttgaag acaacgactt gtgtttgagt tttgaaaaag caggttacaa
     9001 gttattgtac acaccctttt atgcagttat ccatttttac gggaagggtg cgcatcgaaa
     9061 tgcaaaactg tttcgcgtgt ttttgacttc tatgatgaaa tttttcaata agtgggggtg
     9121 gcgttttttc tgatgaaacc agaaatatta gtagtcgttg tgctttatca gcaactattc
     9181 agtcaatctc cagcttatgg accattaagc aaagcactta gcgaaaagca aattcagctt
     9241 attatttacg ataatagtcc tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc
     9301 gtttatcatc atgatccgca aaatcctggt ttagcggtgg cttataattt tgcgttgtct
     9361 caagcagatg aaggaacacg ttgtctcgtc actctggatc aggatacgag gctagtcgac
     9421 gattattttg aactattgcg taaagtaacc tttacagatg aatgtgttgc tgcagttccg
     9481 atgatttttt ctgggagccg acaagtttct cccctatatt cagatcgtta tatcaatcgt
     9541 acagctcaag cagtagaagt tgaaggccca acagctgaac gaatcatggc aatcaattca
     9601 ggtgttgcct ggtctgtcaa atttctaaaa aagattggcg ggtttaatcc tgctttttct
     9661 ttagattttt tggatcattg gctgttttgg aaagtggatc agttggaaaa aactgtggag
     9721 atccttcctg tacgaatgga acatgatctt tcggttttag actatgaaaa agtttcaagt
     9781 aatcgatacc gttctatttt acaagcagaa aatcgatttt atcatgaata tgatcaaagg
     9841 catttatcca gtcaccgacg acaattattg ttaagaacag ctaaacagtt cttgaccgtc
     9901 aaaaaccggc atatctggcg gatgactttg cgctcatatg ttaagaattg gaaggtgtga
     9961 attcgtgcgt tcggtttgta tagctacctt taatggaggc agatatttaa gagagcagtt
    10021 agatagtatt ttatctcagc tttcagcaga agatgaagta gtcatttctg atgatgggtc
    10081 agtagatgat acatgggata tattaactga atacgcagaa aaagataagc gaatccagct
    10141 tttttcgggg cctcgtcaag gattgatcgc taattttggt tatgcgatcc agcagacgaa
    10201 aggagatcta atctttttgg cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa
    10261 gatcactgac tattttgagc agaatccgga tcagctagta gtagtttctg atttaatcat
    10321 tgtggacagc gagctgcaag agatccatga ttcgtatttt tcgtttcgaa attccaaaga
    10381 aggatggctt aataatgtga taagaagtca ctatattggt gctggtatgg ctttccggtc
    10441 ttctttaaaa cccgatattt tgccgatccc gtcagaagtg ccgatgcatg atatgtggat
    10501 tggtttgctg ggaggaaaga agactgggtt cctaagagaa ccgttaactc tgtaccgaag
    10561 acatgattta aacgcgagtg agattgaaac acattctaaa ttacggcaaa aaatttcttg
    10621 gcgtgttcat ctgattacgg cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat
    10681 gtttaaatcc ttaatatttc catgacaaat ataacaattg atgagataat aacaaagtga
    10741 aatttgaaat caaaaaggag agcagatatc catgaaggga atcattcttg ctgggggcag
    10801 cggaacacgt ctgtaccctt taacaaaggc aacatcgaaa caattgatgc cgatttatga
    10861 caaaccaatg atttattatc caatgtctac tctgatgttg gcgggaatca aagaaattct
    10921 gattatttca acgccacaag atacaccacg tttcaaggaa ttatttggaa acggaaatga
    10981 tttaggactg cagatcgaat atgcagtaca agaaagtcca gatggattgg cacaagcgtt
    11041 tatcattgga gaagaattta ttggagatga tagtgtctgc ttggtattag gggacaatat
    11101 ttactatggt ggcggtctgt ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc
    11161 gacagtattt ggctatcatg tcaatgatcc agaacgcttt ggtgtagtag aatttgatga
    11221 gaatatgcaa gctttgtcga ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt
    11281 aactggcctt tatttttatg acaatgaggt aatttctatc gctaaaggta tcaaaccttc
    11341 agaacgtgga gaactagaga ttacggatgt caataaagca tatttggata aaggaaaact
    11401 atccgtagaa cttatgggac gcggatttgc ttggcttgat acaggaacac atgaatcatt
    11461 gcttgaagca tctaccttta tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg
    11521 tttggaagaa attgcttacc gtatgggcta catcgataag gaacaattgc tggcccttgc
    11581 acagccattg aaaaaaaatc aatacggtca atatttattg aatttggccg ctgaataagg
    11641 agtccttaca gatgaaagta acagatacaa aattaacaga tgtcaaaatc gtagaaatgg
    11701 acgtctttgg cgatcatcgc ggtttcttca cagaaagtta ttcaaaagca aaatttgcag
    11761 aacatggatt gaaatatgac tttgttcaag acaaccattc actatcagct gaagctggtg
    11821 tccttcgggg gcttcatttc caaaaaggag aagctgcaca gacaaaattg attcgggtag
    11881 tcactggagc agttttagat gtagtagtgg atatccgcaa aggtagcccg acttatggtc
    11941 aatgggacgg atttatctta tctgaacata atcatcgaca gttgcttgta cctaaaggat
    12001 atgcccatgg attcgttact ttgacaccaa atgtgaactt cctttataag tgtgataatt
    12061 actataatgc agaagcagat gggggcatcg catttgatga tccagattta gcgattgatt
    12121 ggccaattga tccatcaaga gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa
    12181 aagaatttga agcagaaaat ccatttgttt acggagaaat ctaagaatta aggagaaatt
    12241 ttcttatgaa aaacatcatt gttaccggag gtgccggatt catcggctct aatttcgttc
    12301 attacgtggt aaacaatcat ccagaagtgc atgtcactgt tttggataaa ctgacttatg
    12361 caggaaacaa agagaacttg gccggacttc ctagcgatcg cgtagaattg gtcgtaggag
    12421 atgttgcaga tgcagaatta gtggaccgtc tagtaaaaga agcggacgca gttgttcatt
    12481 acgcggcaga atcccataac gataattcat taaaagatcc tttcccattt gtacaaacga
    12541 atatcattgg tacgtataca cttttagaag cttgccgcaa gtatgatgta cgctatcatc
    12601 acgtatctac tgacgaggtt tacggcgatc ttccattacg tgaagacctg ccaggacatg
    12661 gggaaggcga aggagaaaaa ttcactgcgg aaacaccata taatccttca agtccatatt
    12721 cttctacaaa agctggttca gatctgttag taaaagcatg ggtgcgttct tttggcttac
    12781 gtgcaaccat ttcaaactgt tcaaacaact atggtcctta tcagcatatt gaaaaattta
    12841 ttcctcgcca agtaacgagt atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa
    12901 agaatgttcg tgactggatc catacgaatg atcattcttc agcagtgtgg ctgattttga
    12961 cgaaaggcag aattggcgaa acctatctga tcggtgcaga cggtgaagaa gataataaga
    13021 ccgtgatgga attgatctta gaaatgatgg gccaaccaaa agacgcatac gaccatgtaa
    13081 acgaccgcgc agggcacgat ttgcgttatg caatcgattc gacaaaattg cgagaagagc
    13141 taggttggca gcctgagttt acgaacttcc gtgatgggtt ggctgacacg atcaaatggt
    13201 acgaagaaca tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca
    13261 aaaatggaca ataatacaga ggaaatttca ctgtattaat ggaaaaacac atgtgaggca
    13321 ggcgctcgcc tgtctctttt ttaaaataaa aatcaaggag cggataacca tatgttttta
    13381 ttaactggag gaaatggaca attaggtaca gaattgcgcc atttattaga tgaaaaaaat
    13441 ctgccatatg tttcaacaga tgcaaaagac ttggatatca cagatgctga gaaaacaatg
    13501 gcttatatta cagaattaaa acccgatgtt attttccatt gcgcagctta cacagcagta
    13561 gataaagcag aagaagaagc aaaagaatta gatgagaaaa tcaatgtcga tggcacaaga
    13621 aatgtagcac ttgcagcaaa agctgtgaat gcacaattcg tctatatcag tacagactat
    13681 gttttcgatg gaaaaaacaa aaatgtagaa tacgaagtag acgaccaaac gaatccacta
    13741 aatgaatatg gtcgtacgaa attattaggc gaaaaagcag tagaagagat tttagaagac
    13801 tattatatca tacgaacttc ttgggttttc gggatctatg gacacaattt cgtcttcacg
    13861 atgcaacgcc tagcggaaac ccgcgacaaa ctgactgtag taaatgacca gtttgggcga
    13921 ccaacttgga cacgtacttt ggcagaattt atggtatatg tcatcgaaga aaaagcacca
    13981 tttggtattt atcatttgtc gaacgaaaat agctgttctt ggtatgagtt cgcaaaagaa
    14041 atattgaaag atacagatgt agaagttgca cctgttacgt cagaagaatt tccgcaaaaa
    14101 gcaacacgtc cgcagtattc agtcatgagc ctgaaaaaga cagaagcgtt aggttttgtc
    14161 ataccaactt ggcaagaagc acttgcgcaa atgctggaag ctgccaaaaa aatgaataag
    14221 taatttcctt tttatcaaat agaatttgga gcatgatatg gaaaaacaaa caagaagtgc
    14281 acgacgaaaa gaaaagccaa aagcgaatca ggcagattcg aatttggtgc ttgacctgtt
    14341 tctaaaactc cgctatctta ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt
    14401 aaacggaagt tcacttggtg tttgggataa atatgtgtcg caaagagacg atgggaaaaa
    14461 aactgatgtg atttttggac agaatcggga agtgcggtca gacgaatggc tggtgcagac
    14521 acctttttac ctctcacaag ctgaagagga cttttcgttg gtgaacgagg attattcatt
    14581 aaacggacaa aacatgatca ttgcgtataa ttctcctgta aaggatatta cggttatcgg
    14641 aaaaccattc aactggggat tctttttcct cggaagagat cgaggacttt ccttttattg
    14701 ggcgatgaaa ttagtcgtca tggtcttgct tggattcgaa gtactgatga tattaacgaa
    14761 gaggaaaaaa gctctatcgc taatcggtgc atttgcgctg acattttctc cagcagtcca
    14821 gtggtggttc atgcaacatg tgggcgattt gattttcttt actttgggac tgatgattgc
    14881 tttttatcat tatttctaca atcatgataa aaaatggcta cgaacgttga tgatgctttt
    14941 ggtggttatt ttcggtattg ggtttatttt agtgatttac ccagcccatc aagtgatgct
    15001 ggcgtacttg ctgatttttt attttgttgg cctgcttatt tactatagca agaaagtttc
    15061 atgggatctg ttggatgtag tgttgattgg aggggcagtt ttatttattg gcggagtcat
    15121 ggttcatttc tggctaacgt caaaagacgc attgttagct tctttgaata ccttatatcc
    15181 aggaaaacgg gtaagtactg gaggaaagtg gacgattggc gaattttttt ctttccttac
    15241 aaattggaaa attccttttg aagatatcaa ctattcgaat aactctgaag tggccctgtt
    15301 ctatcacttt tttccaactg tattcctagc aagtccattt gtgttatttg gcaaaaaaga
    15361 tagcgaacaa aagttactgg gacgtatttt gatgattttt tgtctgtttt ctatcttttg
    15421 gattaccgtt gggttgccaa aatggctagc agaaatcact ctgctgtctt atgttcctcc
    15481 attaagagcc atccttactt ttagttttgc ggcttgttta ttatcgatct ggtttatcgc
    15541 ttatatttgg agagaagatg ttattcctat ttggtataaa ttcattttgt tggcagtaaa
    15601 tgcatggtct tatttctatg cgattacgca ttcgaaaatg gataattatt tttcggattt
    15661 tgaaaccatc gcagttgctg tgttgggaac agtgatttta gcttttgcat tatttggctg
    15721 gagacgcttg ttttacctcg cttttgtcgc cttagttatc gtatctggct ttttcgtcaa
    15781 tccagtcgta gaaggtacag gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa
    15841 aatcgatcaa caagatcctg gtaaagtttg gttgtctgaa gatgaattat ataacttcac
    15901 cccaacattg ggagtgaaat ccttcaatac agtacgcttt tatccagata tagctgcatg
    15961 gaagaaaatc gatccgaaag aagaatacga gaagtattat aatcggtatg ctcatacaag
    16021 agcttttatc gctaaggaag atacaaagtt cattttagat cgtccagata tgttttcggt
    16081 cacgttgaat tttgaagacg cagaaaaatt agggatcgac tatgtgatca gtaaacgacc
    16141 attaactgat tacaaccaat tatatgaagc gcagttcacg cagctatatg gaccggataa
    16201 agacggttat atgattttta aagtagaata tccggattat ccagatgtac cacaaacaca
    16261 aactcaggaa aatcagctag tcgtacagta ataggctagc tgagaataat cctgaaatat
    16321 tagtagaaag gagagtgaag ataattcaag caatcgtaca aaaatttgtc aacaaaatga
    16381 gtgtcggttt cttgcttttg ttgctgacgc tagtcttttt tgtttggaca gcaggggtag
    16441 gttttccagc aactttgttt atatataaca atagttcatt acttatcgct tttagtgtgg
    16501 ctattttgct cattttaaat gtttataaag caaaaggcgt cgattttctt tatctaggtg
    16561 ttgcgcttgc ccttttcatt ttcttttctt actttcggga attaagaaat gagtctttat
    16621 ttggagactt actgtttcct ttggttattt tattttgttt agtaattaaa tggatcgagt
    16681 ggacaaaatg ggatcgcggt atttatctga ttgtctttac ggtcttcctc ggaatcacgt
    16741 tatatcgtgt atttacagag atccaagtac cagaaggaca aagcatctgg gctccaggca
    16801 attcgctttc tgatatttgg atcaatacga atacaatcgg aagttctttg atgactcttg
    16861 ctttattgat cagtggattt gccagttctt ttgaacgatg gtatgttcga atcatcggtg
    16921 ggatagcagt cgttgcagcc tttttaggta tttgggtctg ccaatctaga ggtgcattag
    16981 tcgcgttgat tgtttttgcg atattggatc ttttacctaa atcgttgatg cgtgtcattc
    17041 gtgcgccatt tattgcctac acggttacga ttcttttagc tttgccgatt tcttatctgg
    17101 cggctgtctc tgaaaaagtc aatttgttta ccgatcgaga agatatttgg cataaattct
    17161 atcagacgct aggagaaaaa tctgaacaag ttttactagg aatgaaaaca tttatcttcc
    17221 agcgaggaaa ccaattttta ggaaaccaca atagttataa ttctattttg aatatctatg
    17281 gattgatagg atttgggatt gctgctttgc tgcttatcct ttttattggt cgcttaacgt
    17341 tgaaagcaga tttatccaac gggcagatga cttttatctg ggcctttttt gcggtgatga
    17401 tgcagtcatt tatggaggat acattgactt catacccatg ggttccgatt atttatatcc
    17461 tgttggctat ggccgttcat cgatatgatg aaccagaagt tgcggaggaa ttctatgtta
    17521 tggaagaggc atatgacgat atgacttatg atgatacatc ttatgaggaa caaccagata
    17581 gcgctcattc ttccaggatc caacgctatc attgataggc acaaaatacg agagaggctg
    17641 tgacaaccgt cgcagccttt tttggtttat tgcaattgtc tagcatcttc tgtaaaatag
    17701 aaacgttaga gaaaatcttg tatcatagaa aattaagaaa gaaataagaa cgcagctcgg
    17761 taccaaaaat atggtaaaat ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac
    17821 acaaatgttt aaagatttgt atttatttat gaaggacatt tatcagaaca gaaaattatt
    17881 gctacagttt tcgatcaatg acttcaaatc aagatatgca ggatcgtttt taggaatctt
    17941 atgggcgttt atcaatccgc tatttactgt attgatttat tggctggtat ttggtgttgg
    18001 actgaaagca caaatgatcg atgcaaaata cccatttatc gtatatttag ttaccgggat
    18061 gattccctgg ttcttcttct cagatgcatt tgcatcaact acggttgttt ttcgggaata
    18121 tacttattta gtaaagaaag tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct
    18181 atccaatctg tacacccatt tattcttcat tctgattggc atagctgtcg cgcttataaa
    18241 tggtatatat ccttcagcaa tgtctttaca gctgatttat tatttatttt gcatgtgtgc
    18301 tttcttgaca ggattgactt ggctgacggc atcgatccaa ccatttttac ctgatatcat
    18361 gcaattaatt acgatcgtgc tgcagttgat catgtggaca ttaccgatat tatggagccc
    18421 taatcagttt gattcaggtc ttgtaagcat attgaaatta aatccgctgt actatgttgt
    18481 tcaaggttat cgtgagtcat ttttaagtga agcttggttc tgggagcatg gaacatatac
    18541 tttgtatttc tgggttttca cgttagtaat gttcgtaatc ggctctgcag tgttccgtag
    18601 attgaaacca catttttcag atgtgctgta aggagaatag ctatgacaga atatgcaatt
    18661 agactaaaag atatcacaaa atcttataat atgtacgcaa aaccttcgga tcgatttcgt
    18721 gaagccctca atccttttaa gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg
    18781 aatgtagaaa taaaaaaagg tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa
    18841 tctacaatgt tgaaaatcat tacgggagta ctgacaccaa catccggcac gatggaaatc
    18901 gaaggaaaaa tctcagcttt gctagaacta ggatcaggat tcaatcctga gtattctggc
    18961 tatgaaaata tctatttaaa tggaatggtt ctaggatttt caagagaaga agtcgatgaa
    19021 atggtcgatg atatcattga atttgctgac atcggagacc atatttatca acctgtaaaa
    19081 acttattcaa gcgggatgtt cgttcgtcta gcttttgctg tagcaatcaa tgtgaatccc
    19141 gatattttga ttgtggatga agcattggca gtaggcgatc ttgaatttca actaaaatgt
    19201 atggaaaaat ttacagaaat caagaactcg ggaaagacga ttttattcgt ttctcatgat
    19261 atcagttcga ttcgtcgttt ttgtgatcgt tcctattggt tgaaaaacgg agaagtcgtc
    19321 gaatatggcg atacgatgga agtaacgacg aattatgaaa actttttaaa gaaaaaatca
    19381 gttaaaacag tggatcggaa taaaaaccaa gtagaacggt tcgccgctcc agatatcgtc
    19441 gacgtgacga aagcggaatt gttggataaa gacaaaaatc cggtggatat gctggaacaa
    19501 ggagaaaaac tatacgttaa agtaacttat gaagtaaaag atgatacaat caaaaatccg
    19561 gttttaggaa ttgcgctacg aacagtcgac aatttttatg tatgcggact taatactcta
    19621 ctagatggta tcaagattcc ttggaaaaaa ggagagaata tcttttatct ggagtatgaa
    19681 aagttaggtt tgttagctgg tgaatattat tttgacgttg cggtctttga agaaaatgca
    19741 acggttcctt tggtatataa gacaaagtac atgaacttgt ttgtcagcgg ttcttatatc
    19801 ggagaaggca tcgtggtctt agaccataaa tgggaagaag ggactcatag caatgaaata
    19861 tgattttgaa atggacctag atgaacaaag cagtgtggga aaaattgccg cacagatcaa
    19921 accaggaagt aaagttttag agtttggtcc cggaaacggc cgattaacga aacatttaat
    19981 cggagcaaaa caatgtgaag tgagcattgt tgagttagat aaggaattgt tcgattttgt
    20041 cagcgaattt gctcaagatg gattttatgg tgatatcgaa agttttgagt gggcaaacta
    20101 ttatgctgga cagacatttg attacgtctt gtttgcggat gttttagaac atttggtaga
    20161 tcctggaaaa acattgaaga aagtcagaga atttttgaat gaagaaggag agatcctgat
    20221 tacattccct aacttggcgc ataattctgt catgatcgat ttgttcaata accaattgcc
    20281 gtgggcttct tatggtctcc tagatgaaac ccataattct ttttatactc atgatggctt
    20341 ccaaaaagtt tttgaaaaag cgggattatt cattaatatt gaagattatt tgtacttagc
    20401 tgtaggtgat acagaattaa aatcaactta tgaagaattg ccggaagctg tacgctatga
    20461 tttcaaaatg cgaccatttg gtgaagtcta ccaatacttt ttctcattga tgaaacatcc
    20521 agtagcacaa agttccattg cagagccaca aaattctaat tatgtaaaag tgttagaagt
    20581 aacccagcaa acgaaacaag atgaaacaat ccaacaaata ccattcaata atttcacagg
    20641 ggaaaatgag acactaagtt tccccgtatc agaaacaaca gaaagaatgg tgtttcgctt
    20701 cgcgcaacaa cctagcttta tcgaattcag cgcagaagct gccggagaaa aactaacatt
    20761 tatcgattcg aatgctgtag tcaaaacagt aaatgattgt tatttgtttg atgggaaaga
    20821 attaccagag ttcgttctaa cggatatttc tgggaaagaa gtgactatcc attgtcacta
    20881 tcgctttatc ggggaattga caccaacaat gaaagaattg ttggaaacga ttcgtcccat
    20941 ggctgaagtc acaaagcagc tttctgagaa aaatgacgaa ttagaaagag aaaatcatca
    21001 tcttcttgag gaaaatacaa gactagacca tacgttaaaa acaaccacaa atcgctattg
    21061 cacattgttg gaaagtgatg aatggacaat aaaacataga ctaggacgac gtaagaaaga
    21121 aacttcgaaa aaaatccaag aaaaagaact ttctatatgt attgacgaga aaatctggga
    21181 tgcagaaaca aaaatattaa aaatcatcgg atggggaatc gctaattcgg atcgccagcc
    21241 cttgtcctat aagttatcag ctgaccaatc gccatttttc gaagcaattc ctgtttcacg
    21301 agaagaagtc aatcaagcag aacagctcgc aaaaggaaca gaagcgggat ttgagttacg
    21361 aatcctttgc gagcaagaac gttcattctt agtggaagca gtagctcaaa atggccaatc
    21421 atggatcatt gaaatgtaaa taatgattaa cttataaaga taaggagtaa acgaatcgtg
    21481 caaaaaaaag aaattgccgt atttatcgat caaatcactc gtgaacgggc cactggcgat
    21541 ttgcttattg tgggctgggc aattgatgaa gtgaccaaag aaatccctac gataaaggta
    21601 gaaaaagaaa atgtgattgc tgaagcaaca catgtcgtaa gattggatat caatcattta
    21661 tataatcttg atgttaagac ccaaagcggt ttcaaggtac gtttatcagg gaaaatgaga
    21721 ggaaaagcca tcttagactt ccaaacagcg agacatcaaa atggcatagc tgtgaaatta
    21781 aacggtaaat acccttatga tgacggcatt gaatcttcat gggaaagaaa aaaaagatta
    21841 ctgaaaaaag ggataaatta tgcaaggact catggcgtaa aaaaagcgat ccgtcgggtc
    21901 aaattggaat tgaagccagg atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa
    21961 ccagatttga aagagcaaag gaaagaagca caaggatttg cgtaccgtcc attgatttcc
    22021 atacttatgc ctgtctataa cgttgaaatc aaatggctcg aaaaatgcat tgattcggta
    22081 ctggatcaaa cgtatgatca ttgggaacta tgtatcagtg atgatgcttc tactgatcca
    22141 gctatccgaa agtgtctgga atcctatcaa gcaaaagatg atagaatcaa agtcgttttc
    22201 cgaaaagaaa atggacacat cagtctggca actaattctg cattggaaat agcagaagga
    22261 gaatttatag cactcttaga taatgatgat gaattaccgc catttgcatt atatgaagtg
    22321 gcaaaagtgc taaacgtaca tccagaactg gatgtgatct acagtgacga agataaaatc
    22381 gatgcagatg gcaatcgctt tgatccgcat ttcaaagcag actggtcgcc tgatacattg
    22441 atgggaaata attatatctc tcacttaggc gtatatcgaa caagcattgt taaagaactt
    22501 ggcggtttcc gtaaaggcta tgaaggttct caagattatg atttggtcct tcgtgtgaca
    22561 gaacaaatcc ctgcagatca tatttaccac attgaccgag tcttgtatca ttggcggacg
    22621 atcccaggat caactgcaag taatggcgaa gccaaaagtt atatctatga ttccggagtg
    22681 aaagcattga cagatgccct gtctagaaga aacatcaaag gaagcgtacg tcctggcaga
    22741 atttctggat tttatgagat tgcttatgac gtcttgcaag aggatttggt cagtgtgatc
    22801 attccaacga agaatggcta tgaagatcta aaaacttgtg tggattcgat catcgaaaaa
    22861 acgtcttatt caaattatga aatcattatt gcggataacg gaagtacaga tccaaaaatg
    22921 caagaattat ttgcagaata caagcatcag ctgaaagacc gctttatcgt agaattgatt
    22981 gacattccat tcaattattc tcgaattaac aatttagcag cagaaaaagc aaacggcaaa
    23041 tactttttat tcttgaataa cgatacagaa gtgattgagc cagattggat gacggtgatg
    23101 gtttcttatg cacagtttga tcgaatcggc tgtgtaggag caaaactgtt ttatccagat
    23161 gatacaacgc agcatgcagg agtattatta ggaatcggtg gtgttgcagg gcatgcattg
    23221 aataactatg atcgaacaca ttgtggttat ttcggccgat tggtcattga cgtcaattac
    23281 ttagcagtca ctgcagcttg tatgatggtc aaggcagctg acttcaatgc tgttaacggg
    23341 tttgatgaaa cattagaagt agcattcaac gatgttgact tgtgcttgaa agtttatgaa
    23401 ctgggtcgtt acaatgtcta tgcacatcaa gcagaattgt accatttcga atctaaatca
    23461 agaggttatg aagatactcc agaaaaacaa agacgttttg ctggtgaaat caaaaaaatg
    23521 caagataaat ggccagcata tattgcgcat gatccatttt acaatgataa tttaacaaaa
    23581 gacggaatcg gcgacttttc gttgagacca gattaaacta taataaaaag ctgttatgtt
    23641 gtgattcgct cgcacataac ggctttttat agttttttgt caaaaaaagg cagaaggtgc
    23701 cgactcaaaa aaataagtcg aggttgggac agaagtgttt aactccgaga aataagaaga
    23761 aattcacgaa aattgctttt caaatttttg tgaatttcgg cttatttaag aagaagttgc
    23821 ttctgctccc accgtttatt cgtttttaaa gaatgagaca aaagtgtttc ttacttttgt
    23881 cccacgctct tattcatgct cagagcgcca atagatacaa aatcatagcc aaagtttcac
    23941 gaaccctagc tgtcaaagaa tcgatatttt attttaatat aggctatttt aaaataaatg
    24001 gtttaaggta ttcctctaca aaagccactc tatcaattat catgggttta aaataagaag
    24061 tgatggagat aaccagattg ttcttagcgt caatataaag aacatttcca ctattaccaa
    24121 ttgctgaata tatttcgttc tcagaatcta atacccacca taaatagcca tatctcatat
    24181 tttgtaagtc ttctaaagca ctggttctag gtttgaacat ctcgtttatc cacatgggtg
    24241 gtacgatttg ttttccttta tacatccctt tatttaggca taatacacca atttttgcca
    24301 gatcacttgc cgataaacac aaaccatatc ctgccgtccc gatatttagt ggatcacaaa
    24361 accagacatt ggttttagga gacttatcca ttgtaaactg cttatgttct tcagctgttt
    24421 cagcataata attgacatgg tttggtatcc ctataggatc aaatagatac ttattggcaa
    24481 aatcaacagt tgttagctta cttgtctgat acaacaagcc agttaatatg tgtaaacaga
    24541 cagtttgata gttgaattcg ccggttatac cttttcttcc tcccaataaa tctagtgatg
    24601 tttttgtcca atcttcactt gaacagactt ttgtccatgg atcgccttta catttgtagg
    24661 gtgctttcat tgttagcaag tgcttgattg taatagcgta aatagttttc tccccgcgtt
    24721 tcactttata ctctggaaaa taatctaata ctttatcatc gatacttttg attaatcctt
    24781 gctctaaagc aatgccaatc agcaaagata caatactttt cgttgctgac atgatatgac
    24841 aagtatcgtc ttttttataa ccattccatt catctgtata aacttctacc ccatccttat
    24901 atgcgacaat ttgacatata tttggttgtc gaaaaccaat aaaatcatgc aactcttgtt
    24961 tattcataag atattacctc actttcttct ataagcataa tgtcattaaa aatcgatttc
    25021 aattttttcg attcttcacg taatacaggt attcttatgg actagacagc gctttgggaa
    25081 gatggattct ctgaaaaata taaaggttca ctttatgagt ggataaaaaa agcagcaaat
    25141 acttcgactt ctttaattta ccaacattag tgaaaatcga ttcatctgga gatttgtaat
    25201 ttagagtcct tgtcttgatt agaggtgtat aaagcttttt attagacatt tttaaattcc
    25261 attacaattt gcttataaac taggttttta aaggtgacta tggtaagata atagagatat
    25321 tattttgtga ttaggagtgt atatatgaat aaaaatggag aatggagtgc tgcacgacgg
    25381 atattcatta tattaatgga tgttattgta tacaatgcag caatatatag tagtttctta
    25441 ctgaagtttc gtggagagat cccattacga aatttagaaa ctttccaaca ctcagcaatt
    25501 attatttcag tgatttttat tgcgttgaac attttgttgg gtgcatatgt tttttataat
    25561 cgaatgatca gtgacatcgt gtttgtcaca gtcatcggtc aggtattgat gacactaggg
    25621 atcatggtag tgacttttgc gggccgctgg tttgcttttc cacgtcttgt tatcttactt
    25681 tcatttgttc tcggtacgct tttcttaagt atctatcgta ttctcgtata taaactttat
    25741 ttacgcgtaa gtcgagataa aaaggtcgtc attattgggt tagaaaagga tgtcgcacca
    25801 gcaatccaaa attttggttc aaagaaaaac aacaaacata aagtcgaagc agtcattctt
    25861 gataactatt atgcaaacat caaaaatatg attaaagaca tcgatattgt ctatcttgct
    25921 tctcatatcg aagaaactga aaaaatcaaa atctatcaat tagttactaa aaatgaaaaa
    25981 aaattgtttt tgaatacaac atttgaaaac ttgacattga tcaatccaaa tattatgaat
    26041 ttcgaagatg aaagtattat tgaagcatct ggatttagaa tccaacctga atatgaacta
    26101 ttcaaacgtt tgtttgatat catcgtttca cttgttttat tagttattgc ttcaccattt
    26161 atgttattca cagcaatttt agtcaaagtg acatcaccgg gaccaatcat ctataaacaa
    26221 gtgcggatca caaaaaatca aaaggaattt tcaatctata aattccgctc gatgaccgcc
    26281 acagccgaag caaaatctgg accagtttta gctaagagca atgatgcacg agtaacgcct
    26341 gtaggtaaat ttattcgagc tgtccgcttt gatgaattac cacaaatctt caatgtgctg
    26401 aaaggcgata tgtcgatcgt aggaccacgt cctgaacgtt ctttcttcgt cgatcagttc
    26461 aatgcagaaa acccttatta ctacttacgg cataatgttc gtgctggtat cactgggtat
    26521 gcacaagtct atggaaaata tgtctctgat tacaacagta aattacgttt tgatttactt
    26581 tatatcaaaa aatattcatt gatgcttgat ttaaagatct tgctgcaaac catcaagatc
    26641 ctatttgata aaatgtcctc tcaaggactt gaagaagacg aaaatgtgat ctcattggca
    26701 gaaattgctt ttccgaatga aaaaatcttt cgctagttgg gaggcgtaaa aatgaacaat
    26761 ccgaaattca gcataatcgt accagtatac aatgcagaag caactattgg tcgaacgatt
    26821 gatattctaa aagaattgga ttatgaagag tacgaagtcg ttttagtaaa tgatggatca
    26881 acagatcaaa cacaggaaat cattcaagaa ctgattgaaa atgatgaacg ttttgaattg
    26941 attactacga ccaatcaagg gcccggatta gcaagaaacg aaggaataag acagtcaaaa
    27001 ggagaatatc tcttattctt cgatgcagat gacacgccag taaaaacgat cttgtcagat
    27061 tatgatcatt tgctagaaaa gagtccaaaa gcggatcttg ttgttagttc gtttgttttt
    27121 cgtacaatgg acgagggaag aatcgtttcc gaaaaagaaa acttagttac agaatgtcac
    27181 tatctaactc acgaagagtt tataaaagac atgtatcagt taatgaatga acagttgatg
    27241 tatgttgtat ggaacaaatg ctatcgtagc gatattctga aaaataacca aattctattt
    27301 aaaacttata atagttgtga ggatcgaata tttaacttac attattatga atactgtcat
    27361 caagtgatca tgaacccaaa agtagaatat atttatgaat ttgaaggtgg gaaggggatc
    27421 actaatcaat accgacctaa caagttcgaa acatttaaag aattctattc attagcaaat
    27481 actgtaacag acgatattaa taaagacggt atggcggcgc ttcttttaaa agggacaact
    27541 tcagttattt tttctattta tagtacctct gcaagaactt caaaagagaa gaaagacaaa
    27601 gcaaagcaga tattgagtga tccagtgatc cgagaagcca agcaaattgc taagacggat
    27661 tcttcagcaa aaaaaataac aaagttgctt tacaatatgc cagctccact atttttatct
    27721 gctgtaaaag ttggaagctt cgttgaagtg aaaatgccag ggttaatggc tgctttgaag
    27781 cgagtatatt agttaatgga ggaaaatata atgaaaagaa ttttgcattt tcagggacga
    27841 atgggtttag gtggagcaga gtctttcatg atgaatttat atcgtaaaat tgatcgtaca
    27901 aactatcaat ttgatttttt gatttatgaa gattatgcag atgttcaaga ctatcattca
    27961 gagattgaaa gattaggagg ccgtattttt gttgtaccta atcctaagaa aaatattttt
    28021 aaatatttaa tagaagtgaa taagttacta aaaaaagaat ctttttctat agttcacaat
    28081 caggtttatt ttggcggggg aattaattta tggttagcca aaaagaatgg aatcagacag
    28141 agaattgctc atagccatgc aactgaagat ggaaaatctc aaaatattgt aatgaatgta
    28201 ttgcgtaaat ttttaaccaa attgttgtta caaaatgcaa cagactacct tgccgttagt
    28261 caagaagctg gtgaaagtct gtttcaaaac catccctttg agatagttca taatggtatt
    28321 gatttagagc tttatagtaa aaattcagaa gctaaggtta ataagagaaa agaattggat
    28381 atctcaatga gtacttttgt tgtgggaaac attggacgat tagagaaaca aaaaaatcaa
    28441 tcttatttgt tagagatttt tttagaaata ctaaaaatga attctgattc ttacttgatt
    28501 ttagtaggtg aagggtcact tagaaataaa ctgaaagcca aagcagtaga attggatata
    28561 gagaaaagag taaaattttt aggagaaaga aacgatattc ccgagttatt atctgtgatg
    28621 gatgtttttg taatgccttc tctttatgaa ggtctgccaa tggttggatt agaagcacaa
    28681 gcagcaaaat taaaattagt cttagcagat actatttcca aagatacaaa gttaacaaat
    28741 aatgtggatt ttgtatcatt agatgaaaca ccacaagaat gggcaaaaaa agtaataaaa
    28801 gagccgtatg ctaataaaat aacacaagaa ctaaagagtt atgatgtttc gtacactact
    28861 gaacaaatgg agagtatata tagtagagat cattaaaaat gttcaagata ttttaggagt
    28921 gattattttt gaaaatatgt tatttgatat tggcatacaa tgatattggc aacttaaaga
    28981 gattggtcaa tcgattgaac gaaaatgcag tttttattat tcatatagat aaaaaaactg
    29041 atatagaacc atttattgaa gcatttaaat catatgataa tgttgaattt ttatgtaata
    29101 aaaaccgtgt taaaatttat tggggtggtt tttccattgt acaagcagaa atcaatttag
    29161 taaagagagc attacaaaat gagaaatat
//
LOCUS       DAFTHM010000027        28871 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFTHM010000027 DAFTHM010000000
VERSION     DAFTHM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28871
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.027"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(251..1558)
                     /locus_tag="L7C88_001184"
     CDS             complement(251..1558)
                     /locus_tag="L7C88_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBP9558029.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(1561..2142)
                     /locus_tag="L7C88_001185"
     CDS             complement(1561..2142)
                     /locus_tag="L7C88_001185"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBP9558030.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(2258..2355)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(2714..4006)
                     /locus_tag="L7C88_001186"
     CDS             complement(2714..4006)
                     /locus_tag="L7C88_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBP9558031.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(4003..4626)
                     /locus_tag="L7C88_001187"
     CDS             complement(4003..4626)
                     /locus_tag="L7C88_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558032.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQPDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(4629..5465)
                     /locus_tag="L7C88_001188"
     CDS             complement(4629..5465)
                     /locus_tag="L7C88_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9558033.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(5482..6369)
                     /locus_tag="L7C88_001189"
     CDS             complement(5482..6369)
                     /locus_tag="L7C88_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9558034.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(6377..7612)
                     /locus_tag="L7C88_001190"
                     /pseudo
     CDS             complement(6377..7612)
                     /locus_tag="L7C88_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
     gene            complement(8295..8978)
                     /locus_tag="L7C88_001191"
     CDS             complement(8295..8978)
                     /locus_tag="L7C88_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBP9558035.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(8996..9613)
                     /locus_tag="L7C88_001192"
     CDS             complement(8996..9613)
                     /locus_tag="L7C88_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBP9558036.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(9623..10447)
                     /locus_tag="L7C88_001193"
     CDS             complement(9623..10447)
                     /locus_tag="L7C88_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBP9558037.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(10440..11000)
                     /locus_tag="L7C88_001194"
     CDS             complement(10440..11000)
                     /locus_tag="L7C88_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558038.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            11174..12130
                     /locus_tag="L7C88_001195"
     CDS             11174..12130
                     /locus_tag="L7C88_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBP9558039.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(12435..13391)
                     /locus_tag="L7C88_001196"
     CDS             complement(12435..13391)
                     /locus_tag="L7C88_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBP9558040.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            13495..14097
                     /locus_tag="L7C88_001197"
     CDS             13495..14097
                     /locus_tag="L7C88_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBP9558041.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(14185..15684)
                     /locus_tag="L7C88_001198"
     CDS             complement(14185..15684)
                     /locus_tag="L7C88_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBP9558042.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(15700..16224)
                     /locus_tag="L7C88_001199"
     CDS             complement(15700..16224)
                     /locus_tag="L7C88_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBP9558043.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            16522..17271
                     /locus_tag="L7C88_001200"
     CDS             16522..17271
                     /locus_tag="L7C88_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBP9558044.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            17262..18047
                     /locus_tag="L7C88_001201"
     CDS             17262..18047
                     /locus_tag="L7C88_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBP9558045.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDGGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            18016..18732
                     /locus_tag="L7C88_001202"
     CDS             18016..18732
                     /locus_tag="L7C88_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBP9558046.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     QPLTCYELTKNGRKKLTDYC"
     gene            complement(18834..19868)
                     /locus_tag="L7C88_001203"
     CDS             complement(18834..19868)
                     /locus_tag="L7C88_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBP9558047.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(19872..20930)
                     /locus_tag="L7C88_001204"
     CDS             complement(19872..20930)
                     /locus_tag="L7C88_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBP9558048.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            complement(21150..22298)
                     /gene="nagA"
                     /locus_tag="L7C88_001205"
     CDS             complement(21150..22298)
                     /gene="nagA"
                     /locus_tag="L7C88_001205"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBP9558049.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(22374..23210)
                     /locus_tag="L7C88_001206"
     CDS             complement(22374..23210)
                     /locus_tag="L7C88_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9558050.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(23394..24611)
                     /locus_tag="L7C88_001207"
     CDS             complement(23394..24611)
                     /locus_tag="L7C88_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBP9558051.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(24760..24939)
                     /locus_tag="L7C88_001208"
     CDS             complement(24760..24939)
                     /locus_tag="L7C88_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558052.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            24994..25077
                     /locus_tag="L7C88_001209"
     tRNA            24994..25077
                     /locus_tag="L7C88_001209"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25028..25030,aa:Leu,seq:gag)
     gene            complement(25317..26687)
                     /locus_tag="L7C88_001210"
     CDS             complement(25317..26687)
                     /locus_tag="L7C88_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558053.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKYVF
                     EKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEI
                     NRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELI
                     FSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLI
                     FLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLF
                     TELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLI
                     MGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFI
                     ITVINR"
     gene            complement(27401..27691)
                     /locus_tag="L7C88_001211"
     CDS             complement(27401..27691)
                     /locus_tag="L7C88_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558054.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(27899..28591)
                     /locus_tag="L7C88_001212"
     CDS             complement(27899..28591)
                     /locus_tag="L7C88_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBP9558055.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQALTDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         8741 a         5991 c         4853 g         9286 t
ORIGIN      
        1 actttttttg atgtcaaaga aatttcgaat gttaacaaag aaaaacattt tattgttcgt
       61 gtttattaaa gatgaaaaaa aggaatgtga caaaagttag gtcacattcc tttttatgga
      121 taaacggtgt tcaatcagct gaccctcggt attagctcaa acaaacggca aaatacgagg
      181 aactattttt ccgtttgttt ctctaacaat caggtcaaaa cgctgatttc acaacctttc
      241 ttttgctcta ttacttcttg aaggcttctt ccaatatttc ttcatctttt ttcaatccat
      301 taaagatcaa attcaatatg atagccgtaa tgctactcat tacgatgcca tttccagtga
      361 acatttgcaa tgtttgcggc atttgactga ataatgtcgg cgtaacattg aaacccagcc
      421 caaatccaac agaaacagca acaatcaata gatttttatc attgctgaaa tcaacttcca
      481 acagcatacg gattccttgg actgccacca tcccgaacat gactaacatt cctccaccaa
      541 gtaccggctc agggatgatt tgtgctaacg caccgatttt agggaataat cctaaaacaa
      601 tcaagaagaa tgcagagaaa tagatgggtt ttcttgtttt gattcccgaa agttgaacca
      661 atccgacatt ttgagaaaag ccagtataag ggaatgtatt gaaaataccg cctaagataa
      721 cggcaagtcc ttctgcacga tatccctttt tcaattcttc ttctccaaca tttttcccag
      781 taatgtcacc aagtgcaaaa tatacacctg ttgattctac catgctgacc atggaaatga
      841 tgatcattag taaaatcgac catacgtcga aagttggttt accaaaataa aagggttgtg
      901 gaacatggaa caacggcgca tctccaatcg cgctcagatc aatcattccc atgaaagcag
      961 ctaagatgct tcctccgact aaaccaatca ataccgcgat tgaacgaatg aacccttttg
     1021 ccagcatttg cacgcctaca attaggagaa tcgtcacaaa tgcaagtagc agatttgttt
     1081 tgtcaccaaa atcagctgct gttgcattac ctccacccat tttctcgatt gctacaggaa
     1141 tcaaagtcaa accaataacg gtgataaccg ttcctgttac tataggaggg aatagttttt
     1201 taattttaga aaagacacca gaaactaaca caacaaagat cccagaagcg ataatagatc
     1261 cgtagatagc tcctactcct tcattggttc cgatcaagat cagtggagct actgcttgga
     1321 tcgcacatcc taaaacgaca ggcaagccaa ttccgaaaaa tcggttaact gtcaattgca
     1381 ataatgtcgc taatccacac ataaagatat caattgaaat caaataagtc atctgttctt
     1441 gattaaagcc tagtcctgta ccgatcaaaa gaggcaccgc tactgctcct gcatacatcg
     1501 ctagcagatg ctgcagccct aaaaccgcag cttttccatt ttgtgtttct ttttccacga
     1561 ttatgcgtcc tcctcaagaa actcaacttg tccattcgtc aaggaagcaa tacgcgcaag
     1621 agaaacgact ctcaatccca tttcttcaag taactgacgt ccatcttgga aagacttttc
     1681 gatgacgatc ccgattcctt ctacttgcgc tccagcttgc tggcataatt cgatcaatcc
     1741 ttttgccgct tgtccgtttg ccaagaaatc gtcgataatc aatactttgt cttctgaaga
     1801 taaaaattta cgagaaatag aaatcgtact tgtcacttgt ttcgtaaaag aataaacaga
     1861 agctgtcaat aattcttcat ccatcgtcaa actttttgct tttctagcga agatcattgg
     1921 aacatctaat tctcttgcag caaataaagc tggtgcgatc ccagaagctt caatggtcac
     1981 aactttcgtg attccttgtt ctttaaatac ttctgcaaac cgttttccca tttgttccat
     2041 caatacaggg tctacttggt gagtgacgaa gctgtcgact tttaatacgc cctcgcctaa
     2101 tatacgtccg tctttttgaa tacgttcaac taattctttc actttatttg ctcctttatc
     2161 atttattaat accgaaataa ccgcttttgt gcaaaaacct actatgtttc tgttaaagaa
     2221 aaacaccctc cactttatca taagaaaaga agggtgaaat agccaatctt ttacttatag
     2281 tccagcattt acggtactgg ctagaaactg tcatccatat tatgacgata tataagtagg
     2341 tatgtaaaac taataatagt gtaaattcat tttcttgcaa ctgttttgca cgtgaaggca
     2401 gtttgccata tttgaataaa aaatgttgtt tcaaatattg aaaacagtct aacactactt
     2461 tctgaaactg acaacgtggt ttacttattt ttttgtaaaa tctaatgatt tttaatgcat
     2521 tattcctttt tgttcgggtt taaatagtta tttttatttt ctcctatcta aaaaagcagc
     2581 ccacataaaa agaaggcatg acaaaaagca tgtcatagcc cctttttccg aataaatagt
     2641 gttcaaaaga cagcctatcg gcaataaggc aagattttat aaactacggg aagtaatttc
     2701 cgtaaatcta ttcttattct tttaagctga caagctcgtc aatcactact gcttttcctg
     2761 aagcaataga atgatttgct gcgattcctg tcaaaatcga caaaatacca tctacgtgag
     2821 ttgctgcccg attccacgga tcttcttctt tttcttcacc aaatagatca tctaataaac
     2881 gcggatctcc tccgccatgt ccgcccgctt cttgttcgac gattacctca tatggctcac
     2941 cgaacatcgg atagacatgg atggactgaa gaacggctgc tccttcatcc tttttatctc
     3001 cacctgcatt gatgtaagac ttttcgatca ctttcatttc gatccgtcct ttgctgccat
     3061 tgaaagaaac attgaatcct tcccacggca tatacgcgtt tagcgaatac gtcaaaatcg
     3121 caccagtttc atatttgacc gttacgccta gtgtatcttc aatagagata tcatcggaaa
     3181 atacactgcg gtcacgaata tatccactgt ctttttctgc ttctaaatac atttctcgca
     3241 attcctcatt ggctgacagg tctatagcaa atggatcagc tttagctagt tcgcttccat
     3301 agcatcgact gtaaaatatt tctactccgc gtttctccgc attatgcatc ccataaaagt
     3361 ttaatccacc gaatgcaaat accttttggg gacggctgtt caaccaaaaa ttcactagat
     3421 caaaatgatg ggtagattta tgaacaagaa gcccgccgct attgtgctta tttcgatgcc
     3481 atcttctgaa ataatctgcc ccgtgttgcg tatttaacag ccattcgaag tggatagaaa
     3541 acacatcacc aatcacatca ctttctatca gttcctttat cttcgtgtga tacggtgcat
     3601 aacgataatt aaaagtgact cgcaggcttc ttcccgtctg tttttggacc gttattattt
     3661 cttgagcttt ttcctcatcg atagtcagag gtttttcgca aataacatca tatccttttt
     3721 tcattgcacg aatgatataa tcatgatgcg ttcgatctac tgacgtaata atgacttcag
     3781 ccggccgtac gtcatccagt agttgctcaa attgtgatgg catacatgtc tttacttttt
     3841 tctgtccata cttgttcaca agtatccgat ttgcataatc catccttgtt tgagatacat
     3901 cacaaaaacc gactagttca caagtttgat gatacgtaga ggcaattgcc tcataaaaaa
     3961 aacgcgctct cccaccaagt ccgacttgta catatttttt cttcatttaa agtcattctc
     4021 cttttctttt aagcaaaata ctgtgacaaa tggcagccct ggatacagta atgcagtgag
     4081 taaaaaatca ggctgtatac accagaacag tccatacaaa aggcataaat accacagaaa
     4141 ccccttgacg ttttttgaca acagccagat attccttttg atcaaataaa caagactatc
     4201 tgctttatct tctttgcaga tatcaattag cgtactaaaa aaactatggg atacaaaaag
     4261 caacagacac aatagaaaag gaatcagata ccaagctcca atctttccca ctaataaata
     4321 ccaatcaact gcaaaaataa tgacaaacag ctgaaacaac gtaatgatga aacacatccg
     4381 tttgattttc cctttcctcc aacatacctt tttttctgcc aagtaatgga cagatagata
     4441 ataagaagga tacatcatca aaaaataaat cagatagaca acacgagcag acagcactaa
     4501 tcctaaagtg aacaaacatc ctagaactaa agcgaaaaga gcattactga taagactggt
     4561 taaaaaaatc cgacagacat agtagttgag cttgtaaaga aacatctctt ctattggctt
     4621 tttcatattc agcccttcag accgcttgta ctgatcccct ggacaagata tttattgaag
     4681 aataagaaaa tcagaaaaac cggtagcagc gacaacgtag acatcgcaaa catactcgcg
     4741 taagtcgtac tagatccagc gtctgcaaat aatttgatgg caatcgatac cgtgtaagat
     4801 ctcggcttgt ttaaataaat caatggtccc atgaagtcgt cccatttcca ataaaactgg
     4861 atgatgatcg tcgtgatgat cgaaggtttc agcaaaggaa aaataatttt ggtaaagaca
     4921 ctatacttgc tgcatccgtc aataatcgct gattcatcta actctttggg gatgctgacc
     4981 atgaattgca tgatctggta aatgaaaaat gcttgtccaa aaaaatgtgg taaaatcagc
     5041 ggcacatacg tcccaaccaa attcagccga ttgtaaataa taaactgcgg aatcaaaatc
     5101 acttgtgcag gaatcatcat cgttactaac atgacgacga accagaatct ttttcctttg
     5161 aaatcgattc tcgataatgc gtaagcaata caagtcgagc tcagaactgt ccctatcgtc
     5221 gaaactgcag agatgacaaa cgaattccta aagaaagtaa aaaatgaaat tccagcaaac
     5281 cccgcccatc cttttgcgta attttcccat tgaaaagtct ctggaatcaa attcagcgaa
     5341 ccactcataa tctcttgatc cgttttaaaa gaacctgcga tcatccataa gaccggataa
     5401 atcatgacta gacctaatag caaaataaaa ccgtattgaa accatttcgt tactgtatta
     5461 ttcatttctt cctcctctca ttcacacaac gacccatttt tttgatgatt tgaaaatcag
     5521 aaaggtgaca gctcccataa tcaacagcat gatccacgaa atagcactag cataccccat
     5581 agaattaaaa gaaaaagctt ggttatacac ataaagagca taaaagttcg tggcatcatt
     5641 cggaccacct tgggtaatga taaatgcctg cgtaaaagtc ataaacgccg cgattgtctg
     5701 cataaccaag ttatacaaaa tgatcggcga aagaagaggt aacgtgatct tgtaaaacgt
     5761 ctgccatttg ttcgctccat cgatctctgc cgcttcataa tacgagcctg ggatctcttt
     5821 gatacctgca gcaaagatga tcattgccga accgaattgc caagcagaca tcaaaacaag
     5881 agggatcatg accagttttt gatcgctaaa ccaggaaagc gcaggtgcgc ctaatcgttc
     5941 caggaaaata ttcactaacc cgtttttaga aaacaactcc cgccaaacta gagcgataga
     6001 aatactgcca ccgatcaaac taggcacata atacaaagaa cgaaagaaag tcgttccttt
     6061 gatattcctc gttaaaagat aagcaatcaa tagaccaaag atcagtttca caggtacaga
     6121 tgcaaataca tagagaaaag tgactcggat ggagttcaaa aaacgggcat cactcagcat
     6181 ctttatataa ttatccaagc cgatccatga gactggattt cccaaacgat aatcggtgaa
     6241 cgaataataa agtgacaaga tcatcggtat cactgttatc aatagaaatc ctaggatgaa
     6301 tggagaagca aatacgtaac cgaccacatt gtcttgatcc aagaaccgtt ttagtttttc
     6361 ttttttcatg ccttccttct gctgttactt cttcataaat gactttttca actaaaagat
     6421 tgtattggtc ttgaatttcc ggattcaaag cactatcaaa gacattcact tcgccgttgt
     6481 ccatatcgga aatcatttct aaataatcaa atgtcgcttg caaagttgca tcatctgcac
     6541 gagcgagctg ttctcgaata ttcgacatga ttggtacacc acgttctcct tttaaaattt
     6601 cattggcttc ttcactgttt tgaaagaaat caataaactt agcagcttct tctttatggg
     6661 ctgagctttt tgccatactc agcatttgcg aagaacgtaa agggatacca gattctccat
     6721 ctgcttttct gcgaggtgga ttaatcaact gaatctccat atcttcagga gcccctgaca
     6781 atatttctgt caactggtta cttgatagaa acaccattgc cgcttctcta tccctaaccg
     6841 cctgaaaaga cagatccgtc gtacttgcag ctccaccacc tggttctgga tgggcccctt
     6901 tgtctaccag atttttacgc agctggaaaa aatctgttag atagtctgga ttttcaaatc
     6961 ccaagctgtt agatagatct tcccgattat aaaaattcaa tcctttctca acttgtggta
     7021 tttgaataat acagccagct ataaaatctt cgaatcttga aatagcatag attcctaatt
     7081 cttcagtgat ttgatagctg atttgttcaa attcatccca tgtccaattt gaagctggtt
     7141 cagggatatt taattgttca aatatatttt tattgtaagc aatcgcaaac gaattcaccc
     7201 cgttagacag tccaactaat tgcccgtcgt aagtcgtcgt tgctaaatag gattcatctg
     7261 cattagaaat atcaattatc ccttgctcca catattcatc taatggttca atctgattga
     7321 tgtattgagg aaattgattg ttcagttgga aaatgtccca gatatcatct gatgctgcta
     7381 gtgtacctaa ttttgtgtaa tatccttcat aatcataaaa ttcataatcg atcgtcacat
     7441 ggggattttt ttcttcataa agctcgatta cttttactgt tgcatcgtgt cggacttgcg
     7501 aaccccacca agccatgttc agcgtgattt ttttgtcatc ttcttgccca caagccgtca
     7561 agaagaataa cataacactt aaagctaaga tgattctcat tcttttcttc attctctgca
     7621 cctctacttc cattgttatt tttcaatata ctgtattttt atacagaaca tatttattaa
     7681 acgatctttt tcaaggggaa taaaaaccaa gacttgcctt atcgttctgc ctaggatgaa
     7741 caactcaata ctttcaagaa aaattagata gtgctgattc ttctttcatc gctaaaaaca
     7801 cttcttgctt caatgatggg aggataatta cgcaaagaaa aaaggatatc agacaactgc
     7861 ccaatatcct tgacatagct aaataagcat gcttcttcgt gtgcgctctt ccctaaaaaa
     7921 cagaaaaata actagtaatt ctgtatgaaa ttaggtacaa tatacacgtc gatgcacaag
     7981 cattgactat ggcaacttga ttggtcagtt cccgctgact tttcaagccc cgacaattta
     8041 gctgctacta aattgtcggg tgcctttttt agtttttatt cgtttttcat tctatagaaa
     8101 gcgcttcaat aaatcaagac atttttttgt tagaatgcta ataataacaa aaggttttaa
     8161 ctcttcttat gtacattaca ggtaaaaaaa caaaaaaatt tctctttttt ttgaattctg
     8221 aacaaatagt actggagtac aaaagacgag gaagagccac tatctgctct tcctcgtctt
     8281 ttgattctca cctgttattc atgattcttt ttctcagttt cccgatattt ttccatttta
     8341 cgactaaaaa gctctccgct acttggtggc gtatatgtga tggcatttgc tcctgcttga
     8401 atggtctcag caatactttc ttccgttgga ccacctgtcg caatgatagg aagttcagga
     8461 tattttttac gaaaatggcg tactgcttct gcagtttctt tacctgcact gatattgata
     8521 atcgaaatac cagctgctaa cttttcatct atttctgtat atttcgacgt taccgtactg
     8581 ataactggaa tatcaactac tcgacaaact tcttttactg tctctaaagg cgtaggaccg
     8641 ttcaaaacga cccctaacga accttgcgct tctgcgaaca tgctcatgta ggaagaacga
     8701 gcaccttgtg tcaaaccacc acctacaccg gagaaaactg gaatgtcagc tgcctcaata
     8761 atgcttttag taatcgctgg atgaggtgta aaaggataca cagcaattac tgcattcgca
     8821 tttgtattac gtatgatcgc aatatccgta gtaaagatga tcgaacggat caattttcca
     8881 aatatcttga tcccgcttgc ttctaaaatg atttccggta ctcttacgat atcttttctc
     8941 aattccgtca tgatttctgg cgtaaattgt tctgccatca gccacttctc ctttgctatc
     9001 tccggtcata ctgattcaat tgatacgtct cgatgacctg gatgattttt tgcgcataac
     9061 cggggtctgt cgcataacct gcatcttgca atgcttgtgc ggcttcctga tagttggtgg
     9121 ccgtaatcac tttttcatac agcgcaggat tccaatctac tccttggacg aacagttgtg
     9181 tatggtcatc catggactgt tcccatgaat catacacttt gaagtctcct tggatagtta
     9241 tccattcttc gttaacaaat tcctttgttt ccaggcttac tttcttctga tccccataag
     9301 ccttgatccc gaaaagatta ttgtatttgc tagccaaggt actttttccc caatttgatt
     9361 ctaatatagc ttgtcctaaa atgatactag gaagcactcc ataaccatct tgtagttctt
     9421 gggcatgcgg aacaagccgt tcaataaatt gctgatggga ttgcgcttca ttttcttgct
     9481 gattatcagt aaaaggagaa gacagattct tcaaggaaaa aacaaaggct aagagtatca
     9541 ctgctacacc ggcaaccact gctggccaac ggatattctt gcgcttttgc tttttccact
     9601 tttttttcgc catgatcaat tcctactttt catttaattc attcagatat tcttctagcg
     9661 tcaattggtg tttggtgata tactcagcgt tttctttacc gacataacgt aagtgccaag
     9721 gttcatatgt gatcttagtt atatcttcgt gtccttttgg ataacgaacg ataaatccat
     9781 actgcgcagc attatctgcg atccatttag ctccaggctg atctccgtaa cttgcatcca
     9841 atacagtaga aggataactg ttgtaccagt tttgatcgac gacatcgact gccagacctg
     9901 tgtggtgttc gctgtatcct ggctccgtaa tcgtttcttt agtaatcttt gtcgcctcct
     9961 cttctgatac accttgacga ctcatcacat cttggacatt ttgttcgaaa acttgttgtt
    10021 gggatgatac agaccggtaa gctgagacca tcactaatgg aaatccagct gcttcagcag
    10081 ccttggcaaa tgcttcatat tctggagcaa tgcgtttgtc gatcaagtat ccgttactta
    10141 atgatgccaa ttgagtagac tcatcaattt ctttttctaa tttgtgatct ggaccaacca
    10201 aaactagctt ccaatcgtct gttttaacat ctggcaattg tttggacgta cgatcttttg
    10261 tttctttgtc ctttaccttg ctgctggttg tttgactgtt cttttcttta ctagcagttg
    10321 ttttggtgct tgttcgttcg actgcttgat tgccggcttg aacatgcgaa tcatcatcgc
    10381 taaaaataac atagcccatt gctgcgatca taatcacaac tgctccaaat cctaaaaatt
    10441 tattcacttg aaaaatcctt tcgttgttct tcacgttccc cattcgcctc atgaacgtaa
    10501 gtttcttcca gattttcatt cacccaatcg agaagttcga ttttttctcc ttcgatctgt
    10561 ttttgaacat ctgctggcag acgaaaattc aaaatatcat catagcccca ttcatcatat
    10621 tgaatactta ctttcaagtc aaggtatcta ccagcctgct gattattttt caaagggatc
    10681 agctcgactt ttgctgcttt gctgctaagc catttttgcg cgatgcgtgt tttgatttgc
    10741 ttgtactctg caacggcaac gtttcgtttt tcgggaaaaa taatcgtttg acgcaaaatc
    10801 ttttgcgtta gcatccattc ataatcagtg aaaagatttt ttactttctg catcgcttca
    10861 gatggcagat ttttctcgcc atctttccat ttttgccatt gttctggact gatcagcaag
    10921 tattcatcta aaaaattttt ttcagtttca aactgttcta ataatacact cataataaga
    10981 tcaatatata cttgatgcac gtttatcccc tccttttaac tattctactt aagttttgat
    11041 caaaaagcac ctcttaaatc gctgctttca ttttttttaa tgtttcaagt cctctcctct
    11101 ttattcttcg tgatttttgt tataataata gacagacaag aaactcaatc caactatgaa
    11161 ggagcgtttt cagatgaaaa aatatcaatg gggaatcgtt ggtcttggta ccatcgcaca
    11221 tgagtttgcc gaaagcttca atcaagagac gagcgaacta acagcagttg cttccagaac
    11281 ttcagaaaaa gcggaaaact tcgctcaccg ttacaatatt ccaaaagctt acggaagcta
    11341 tcaagaaatg ttagacgatg ctgaaatcga catcgtgtac attgctgtac caaatagaca
    11401 gcatatcgac catatcttgg cagcattgga agcaggcaaa cacgttctat gtgaaaaagc
    11461 catcacgatg aataaaaaag aactggctga cgctatgcgc ttagcagaag aaaagaattt
    11521 gatcttagca gaagcgatga caatcttcaa catgccactt tatcagcagt tacgctcaat
    11581 aatggataca ggaaaactgg gggctttaaa aatgatccaa gcacctttcg gcagttacaa
    11641 agaaccagac cctaaaaacc ggttcttcaa tccagaatta gctggaggag ctctgttgga
    11701 tatcggtacg tatgctgtat ctttcgctcg tttctttttg agctctcaac ctgaagtagt
    11761 tgcctctaca atggttcctt ttgaaacagg cgtggacgaa caatccgtca ctatcttgcg
    11821 taacaaagaa aatgaacttg ctgctgtcag cttgactttt caggcaaaaa tgccaaaagt
    11881 cggtatcgtt gcctttgaga acggttatgt gacgattgct gattacccgc gtgctgatcg
    11941 tgcggagatc ttatttacag atggtacaaa ggaattcatc gaaagcggga atacatctga
    12001 agcaatgaat tacgaaataa agaatatggt acacatgatt gaaggtgact tgcccaatcg
    12061 ctctctcttc ttgacaaaag atgtcatcga aatcttggat caaatgcaag ttctatggaa
    12121 aaatatgtaa ttttaaaagg ttgtgaaaaa gctgttctgc atcaagtaat aagaacagcc
    12181 aaacaaaaat agctcctcct atttttcgtt tggctggact tattaccgca gaggaaagct
    12241 tttgaacacc gtttaagaaa gaggttgtga gcctaccgtt cagctccgag tcacaaggag
    12301 caatttcaaa aaacagcttc tcatgtttgt tgaatattgt gacttgtgac cgaggagttg
    12361 acaggagaac accgtttaaa gaagaggttg tgaaatcagc tttttgacct gaatattagc
    12421 tgaattcaca acctctattt ttggattttt tgttgggaga attctgcctt gatttcaata
    12481 aaacttttaa aagactgcaa aaactggaac aattctgctc gatcctcgaa ttcagggcga
    12541 ctagtcggca gaggcatttg ccgatacaat acataaactt cttcaatacg tgttaaaatt
    12601 tgtctgccat catttgactc tgaaaatgtt tctgcagtat aaatcaataa accatagata
    12661 tgttttccat aataagctgg ttgctggatt ctctctagat tttccagcat gtctttaatc
    12721 acattggcct gtgctcttct catagagaag taagtttcgt agtatagcgg ctgtctgagc
    12781 cagtagtttt cttgatgttc tctggcatct tcttggcttt cgcgaatgaa tgtcagtaaa
    12841 tgttcgcatt tgatctgcac atcttcttta ttttctgata aaagaaattc tgccatttgt
    12901 ctcaaaatat ttcgaaattc tttttcgatc tgtatttggt tttccttcag ctgcttcgta
    12961 cgatctggca tgtaaacatt tgcaagcaaa gcaaatacta atccaatcgc cattaatccc
    13021 gcttcattgc cgatcagctg ccaagacatg ttttcctcca ctaaataatg agtgaccaaa
    13081 accgaattta ctactatccc ttcggttaat ttgaagcgag aggcaagcgg gatgaacagg
    13141 aataaaaaaa gactgaagcc aaaaatagta tacccaacag caaaaaaact gaacagtgct
    13201 gttgccgtag ctaatataaa ggctgcgatt cgattcatgc ccgtacgcaa tgtagagcgc
    13261 ttggtatttc ctacacttaa taatgcaatg atccctgcag ctggccaata caacagcgat
    13321 aagctacccg ctgtgaccat cgaaaagaag acactgatca ctgttttgac tgttcgcatt
    13381 cctatacgca tttacttccc ccttttttat tttaattata cttgaataat gaaaaactag
    13441 ctatcagaca aaagtttagg tatgatagta aaaagaccaa aaaggagaat ctctatgcaa
    13501 tttggccgtt ttcgactagg tatgcgtacg atcaaaagtg ccttagctgt ttttttatgt
    13561 atcttgtttt ttcatttgac tcaacgagga atcccgatga ttgctgcatt atctgctgtt
    13621 ttttctttgc gtcaggactt gactacaacc gtttcttttg gaaagtctag gatcatcggc
    13681 aatacattag gtggtacatt agctatcatt tatttttttg tcaaaagcta ttttcacaat
    13741 gattttttgg tagaattgat cttgcttcct attctagtta ttattgtgat cgtcgtgtca
    13801 gatggtatta acaataattc cggtatcatt tccgcaatag ctacgttgtt gctgattgcg
    13861 ttgagcatcc ctcaaggcga atccgctttg tatgctatcc aacgtgtact agatactttt
    13921 atagggacat tcattgcaat cggtatcaat ttctttcttc gtcctcctga aacagaaaag
    13981 aaggaagaac tatcagaaga tttggtcgaa ctccaaaaga aagaacgatt gctaagaaca
    14041 aatttacaag agatagaagc taagatccaa aaacaaaaga aaaatagcga ggactaattt
    14101 tcttttgcaa taaaataaaa aaatggagag aagaacttta aaaagtcttc ctccattttt
    14161 gattgaacgg tgaagtgtac tactttattc ttccttcatc gagttttgtt ctgcctcttt
    14221 tggcgcttca tacatattta cttggctagt agtcccacgt gtcgacaaat tctctacgat
    14281 ttccttcaag tcaagtcctg ttgtcgcttt tagtgtttct tgagtagaag aaagcaaatt
    14341 tgtggcataa tttgtcactc ggttcgctcc actggtttct cctgaactgc ttcctgtatc
    14401 gacaacagag attttttcga tatttcctag cggctgtgct gcttcgcgca tcaattgcgg
    14461 tagcatatcg ataaccatac tcaagacagc tgcttcgcca tattccttga aggcattggc
    14521 gatcttttgt tttgcttcgg cttctgcttt tccttttgct agtgctgctt cggcttctgc
    14581 ttgtccagct aaacgtgtct tattggcttc cgcttctgcc agtgcttcca cacggaatcg
    14641 ttctgcttcg gcttcagtca cttctttgac tttttgagct tgtgcttctt gttctttagc
    14701 gtaccgatcg gcatctgctt ttttcttcac ttccgaatca tattgctttt cacgacgtgt
    14761 gatttctttt tcttccagtt cgatttgttt ttggcgttct acgattttaa tctgcatttc
    14821 ctgttcgatt acttgttgtt gtgctcgggc actttctaaa ttgtaggctt ggtctgcttt
    14881 tgctttagca acatcttgtt cttgtttgta ggttgctaat ttcagttctt tttcttttaa
    14941 tgattctgcg atctctgttt gtcgctgtaa ttcagctgct tgtgattctt tttctgcttg
    15001 agcttttttg atacgcgttt cttttagagc ttccgcttct gctatatctg catctctttt
    15061 gacttgggcg attcttggtt tccctaaaga gtcaagataa ccgtttttgt ctctgacctc
    15121 tttgatagtg aaagaaacga tgatcaaccc catttttgca aggtctacag aagcgacttc
    15181 ttgtacgctt tgactgaact tatcgcgatt ttgatagatt tcttctacag tcatagaacc
    15241 aagaatcgag cgcaagtgtc cttctaatac ttctcttgct tcattttcca gttcttctct
    15301 tgtcttgcct aaaaactgtt ctgctgctgt agcaatctct tctacagatg aaccgatttt
    15361 gatgatcgaa gtaccatcac acatcaccgg tacgccttgt tcggtataca cttcaggggt
    15421 ggagacgtcc aatttactcg ataatagact gatccgattc gaacgttgaa aaactggcaa
    15481 gacgaatgcg ccacctccac gcacaatttt gattttgtta ttgctttcat caatgtgcac
    15541 atttttgctt cctaaataac ttccactgat gatcaacgct tcatccggtt ttgctgtctg
    15601 gtacttcgct acaaagacga tcagcaacat cagtaaaatc aaagctgcga ttgcgatcgc
    15661 gataaaaaca actggtattt ccatttaaca cacgctcctt taagctttta tcatgctttc
    15721 ataaggcatg acataacaga ttctttcctt gatctcaatg atcaatactt tcgttccccg
    15781 ctcagctgtc tgttcttggg ggctgtaaaa acaagctgga cgactaatgg aaccggtaac
    15841 acttttcaac tgaatttctc ccatacctcg tacagggatc ggtgtgatca caacagctac
    15901 ttgtccttcc agagtttttt cagaagacga catcgttgat tcggcatgtt tcatcggcat
    15961 caatatatag aaattaagca aaaataccaa cactatcgat atgcctccac tagcaataaa
    16021 taaaaataaa gatgattgat ctgttaaacg ctcacctaga aaaccaaata agcttgtgaa
    16081 agttaaccaa gggataataa gcatcggatc aagcgggcca tcaaaatcga atacatctcc
    16141 aaaaataatc aataggactg ccaatcctgc acaaatcagc aatgtatacc aataaatcgt
    16201 ctcaagtgcg attcccccta tcatatacac gcctccttcc atttctacgt ctatcatacc
    16261 aatgtttgaa aattctgtat agcttctttt accgactcag tggtgttttt tataggaagg
    16321 ttgtgtttat cgttgacaat ttgttaaatt tttgttttca tgttaaaatt ttcacaataa
    16381 attctttcga ggtagcctat gtttcctttt tttaagaaaa aaccattaaa gctccagaac
    16441 acgatcatcc ttgtcgtttg tttctccaca ttcgtttctt tgattgtttc tgccatattg
    16501 atcaggaatt ttattctttc gatgaaccga tctagtgtgt cagataaaat ctctagcatt
    16561 gctaaaatcg ttgccaatga taaactcatc caaaaaaagc tgcagactgg tgacccgaca
    16621 catgcgattc aaggaataac aaatgaaatc atgattgcat cgaatttaga ttttatcgtt
    16681 gtcatggacc ctgaaggcat tcgatattct cacgcagacc caagttacat cggtcttcct
    16741 ttctcaagtc atgaagatgt gaaaaaagtg attggaggac aagaattttt ctctgaaaaa
    16801 gaaggaatgt tagggttcgg cttccgctat ttcgtcccta tttattatga tcaagagatt
    16861 attggtgcag tttgtgttgg cttaacaaac aacacgattg acaatcaagt caaagatgga
    16921 caaaaaatga ttgttttttc attgattatt ggacttagcg taggcatcat aggcgccgtt
    16981 tttcttgccc aaaaaatgaa aaaagtactg cttggacttg aaccacaaga aatagcagaa
    17041 cagttaagtg aaaaaacgat tatcgaaaat gaagtagatg aaggaatctt agccatctct
    17101 tctgataaaa ctatcctctt gatcaataca cctgcaaaaa acattttcta ccaaacagag
    17161 cagctattgg atttcgaagt aggaaaaaaa tcagtgataa tctatatgac gttttgttta
    17221 aagagacgat tgagcatcaa acgaccgttc ggactcaatc catgtattta aatgggatag
    17281 aaactatttc tagcgttaca cctcttttta gcaatgaccg ttttttagga gcagtcgcaa
    17341 ctttacgaaa tcgatcagaa gtaatgaaat taatggagga gcttgggggg acgaaacaat
    17401 atataaactc catgagagct caaacccatg aattcatgaa taaacttcat gtcatttctg
    17461 gtttgattga tttgaagaag tatgaagaag tcacccattt tatccagcag ctaaatcaaa
    17521 attataaaaa agagattggc caagtctcaa gtctgatcaa agtacctgca attgccggtt
    17581 ttttattagg caaaataaac gaagccaaag aacaatctgt tgaaatgctg ttagaaagcg
    17641 attcttttat ccctaaaatg gagatggatg actccatcca ttcacttttg caagtgttag
    17701 ggaacttact tgataatgca aaagaagccg tgctacaaaa acatgaaaga aacggacagg
    17761 tccggattca tttaaactat gacacagaag ctgaagtatt catcgtgacc gtctgcgatg
    17821 gcggtgtcgg gatatcagaa gaaatctcag aaaaaatatt tacgctaggt ttttcgacga
    17881 agggaatcaa tcgtgggttt ggattgaatc tcatccattc aatcgtcaaa cgccacggtg
    17941 gatttttaga attttccaaa caaacaaatg gcggtacaat cgtctatcta gaattaccaa
    18001 aaaaggaaga tcaaaatgat gacaaatgtc ctgataatcg aagatgatcc aatggttgca
    18061 gaattgaatc gtacttttgt ggaaagcatc cctaatatga acgtaatcga aagtttcaga
    18121 aatgtagaag aaggaaaaaa atatttcaga caaaaaaacg cagatctgct gctgcttgat
    18181 gtatacatgc ctggcgaaag tggtatccat tttttatctt ggcttagaca gcaaggaaat
    18241 gatatcccag tgattttgat cactgctgca gatgatatcg aaaccataaa gaatgtgatc
    18301 cgctacggtg ccttagatta tttgatcaaa ccgttcactt tgcaacgttt tcagctggcg
    18361 atcgaaaagt atcttgcttt ctctcagaca atccaaacga ctgaaaaagc cgatcagaaa
    18421 ttgatcgatc aagtattcaa ccacaccact cccattcacg aaataccatc attcatcgat
    18481 ttgcctaaag gtctgtcaaa actgacttta aaaaaaataa gtgcatttat tctaaaagaa
    18541 gatactattt tttcaacaaa agaactggct caaaaaagct cactgtcacg tatatccgtc
    18601 aagaaatatt tgaatttttt agtagaacaa gatatattga acgaaagaat caaatatttg
    18661 gaaatcggcc agccgctaac ctgttatgaa ttgacaaaga atgggcggaa aaagctcaca
    18721 gattactgtt gagtcatcga attatcccat acaaaatagt ccaagtatac agaagtaaca
    18781 actgtttact tggactattt ttaaacattt tattgacgaa tatccatgtt ttcttatctt
    18841 aattgacggg ctttaggaag agatacctca tttttcgttt ttccagtttc tattatttca
    18901 cgaaagttct cgaaacttgt cgaaatcata tttgataatg cctcatctgt atttgaacct
    18961 acatgcgggg ttacaagaac tctagggtac atttctacta attgctggat agcagggtct
    19021 ggaatcgtct cccatggctt gaaggatcgg aaaaaaacct ctgtttcatt tgcaaaaaca
    19081 tcggttgcaa aaccagctaa atgattgctt ttcaaagctc ttaaaatagc ttcattatct
    19141 tgaagctctc cacgggctgt attaatcaag atgctacctt ttttcatttg agctaaaaat
    19201 ccttcattga tcatttgatc gttttcacct gggatatgag gtacatgaat actgacaata
    19261 tcgcttttgg ctaataactc ttcaagcgag tggaacgtca atactttttt agcagcttct
    19321 gtctgatgaa tatcgtagcc gatcactttg gctcctagtc ccttaaacaa aacagcttcc
    19381 gtcaacccta tcctgcctgt tcctatgatc cctactgtgc aatttctgat ttcacgacta
    19441 aacatttgct catccactcg aaaatctttg aaagatgttc ggatcgtcgt atacgcagta
    19501 tttctcaaaa gcatcatggc aaaagtcaaa gataactctg ctatcgcatt tggcgaatac
    19561 gatggtacac gggctactgt cataccaaaa tcagctgccg cttgtagatc gatatgattg
    19621 actcccacag tccgtgtaaa aacataacga atcccatatt cctgcatttt tgcaagattg
    19681 gtctcatctg ctatacaatt tcccctcaac aatacagcat catggtcctt tgctgacacg
    19741 atattgtcat gtgtcaacag ttcttcataa agactgagat cataatggta aatattcaat
    19801 ttttcaaaaa aatctatctc gttcggacga acaccgtaac atgcgattct catactttct
    19861 tcctccattt cttatgaaaa taaacctatg ccatgaatca tttgtaatac aacgatccat
    19921 acaggtgtca gtaccacagc aaaaatagtt gacagtaagg atgcattgga ggctaaaagt
    19981 gcctccctat caaaactgat agcataggct gctgccactg ttgcagctgg tgtagccatc
    20041 atgataacga ttgttgccag tgcttcaaaa ttgactggta gaatattcgt tgccgtcaaa
    20101 actgctagaa tcacgatatt caatgcaggt acaaatacca ctttgactag actgtaatac
    20161 catgaagttt tttcagatgc agcttttttg aagcttactt cacctaatgt tgcgccgatt
    20221 gctagccacg ccaatggtga acttaaacca gctaaataat ccatcggctg aaatagccac
    20281 ggtgcagtct ggtcaattcg caaaaacgct acttggctta tctctccttc tgcacctgta
    20341 actgacactt gtggcagata cccttggaac agccaaatga aaaggccggc aaaagtagcg
    20401 ataatgattg gattgacgaa catcgctttg atatttttag cttccatctt caagccactc
    20461 atttttatgt atccataaga atacaaaaag attcggtagc caatattgaa aattgaggaa
    20521 tacatcacgc cgacaggacc ataaatcgca ctgacgatag gcgttccgaa aaaggtcgta
    20581 gaaccaaaga tcgtcaggac acgcaacgtt gtttgcttat cccctttata gcttaagaaa
    20641 aaaggttttg aaactagaat aagaataata taaataacta atccccaaat caagacattg
    20701 attccttgca tcagtaattc tgtattgata tcttgcatga aagctcgaaa tgccagtgct
    20761 ggcaaagcca ctgttaagac gactttcgat agaatttttc caacagattc agaaaaaatc
    20821 cccttttttc tacaaacaaa ccctaataat ataataaaaa ctgttgaagt gattgcactg
    20881 acaatcgaca tatctgtcaa agtcgatcga aaaatgtcaa ataagttcat ctttctcctc
    20941 ctaattatgt tcatttattc acaataaaaa aagcttttat tttgctaata cgtattaaca
    21001 tttttaattt tatctttaca ttgttactta ttgaacaata ggaaattaaa gaaacttttg
    21061 aaacttatgt aaagtgattt ttactagaac acaaaaaaac cttaaaacca aacttaagaa
    21121 gtttagtttt aaggttaact taaattatat tatgcgtgga aacgttccac gccatctaga
    21181 taagttgctt ccaatgtcat atcagggttc aatacgataa agtctgcatc gcgtccttga
    21241 gcgatttttc cacatgtatc atcgatttta cagctgattg ctggaatcag actagccatc
    21301 atgactgctt gttctggtgt tgctaatccc cagtctacaa catttttaat tgcttctttc
    21361 aatttcaata tacttccagc taagttgcca gattctagac gtgctgttcc ttcttttact
    21421 actactggaa attcgcctaa attgtaattt ccatcaggca tcccaccggc catcatacag
    21481 tctgtaatta atgcgacatg atcatgtcct gctttttcca ttaggattcc cgcagcattt
    21541 ggatgtacat gatggccatc acaaatcaat tcagaaaaga catgttctaa agataataac
    21601 gcacccacca tacctggttc gcgatgattc aatccacgca taccattgaa agcatggaca
    21661 aatacacttg cgcctgcttc aacagctttt tgcgcttctt ctagtgtagc attactgtgt
    21721 cctagagaaa caactactcc ttcttcagtc acttgtttga caaactcttc tacaccttga
    21781 cgttccggtg ctaaagcaat ttttttgatt aaaccacctg aagcttcttg ccattcatgg
    21841 aaagtatcca aatcaggatc cccgaaataa cttgggtttt gtgccccttt gtgttcttct
    21901 gtgaagaaag gaccttcaaa atagattcct ttgattttag ctcctggtgc ttcctgatac
    21961 attttgccga ttgtctcagc tacatctttt aaacgttctt tgcttgacgt caatgttgtt
    22021 ggtaaaaatg aagtcactcc acaagataac agaccttcag acatcacttt gatgccttct
    22081 gcatcattat ccattacatc atgattcata tagccgtgaa tatgtgtatc taccaaacca
    22141 ggagcaatcc atttgccgct ttggtcaatg atgttgactt ctccctcagg tagttctttg
    22201 gtgtattcac caaaaagtcc atcggtaatt tcaagatagc ctgcatgttt gacacctgac
    22261 gctaaaaaga atttgtcagc atagataaaa gttctcattc tattctctcc ctttgttttt
    22321 ctacctctaa agtactctta tttagagaag aagtcaagaa tggtctacac catttacaaa
    22381 ttttttgaaa tttgtttcac agcttgtgct aagccttcat agaatgctgc tctttctggt
    22441 tcttctttac gcttgtatat taagctttta agcacaaata aatcattgag gtaatagtag
    22501 ctattcttct cttgagccca atagattcct tgattcacct gttctaacgc ttcgtcgatt
    22561 tcattttgat ggaataagaa atttccataa ttataaaaaa tttgcgaaaa ttcacttttt
    22621 gatcgttcat cagctgattg atgcagcagt tggatgcttc gactcaaata gtagcgtgct
    22681 tcagccgttt ttcctgccac accatatatt tttccgatac aactaatcag ttgtatttct
    22741 gtgtcagaaa catggattct ttctttttgg ctagagtagc ttaatgcttc tttcaaataa
    22801 taaagggact gagagatatt ttgacgcaac gtgaattcgc aaacaccgag ataataataa
    22861 tagcgttgaa agtcagttgc ttgatacaga ttttcagaaa tatcagaaga ttttagtact
    22921 tgttctaact tccgataatc acgtttttgg aaacaactat ccaacagttc aaataattta
    22981 tcgtttgtcc gagtagtttt tcgagagaga ttcatcacat gatcaatcgt tacccctagc
    23041 cgttgacaaa tctgcatcat caccaataca ttcggcagtt cctcattatt ttcgatccga
    23101 cttaatacac tttgtgaaca aatatcatgc gaaagcattt tttgcgtcat tttttgttct
    23161 tttcgaatct ctttaatgat cgttccaaag gactcgatta acgtttccat aagtatcctc
    23221 cccaaaatat gcgtattcgc attctattcg tattttactt taggaagtcg caaacttcaa
    23281 gaaaagactt gcaactaaat aatatacttt agttatttaa gaaaactcca ctagaaagag
    23341 agcctcagtg tgtttgtctg tggccctcct actgaaaaat ttggttttta aaatcatttt
    23401 tggcgatagg ttgctaggaa ttctctcatt ttcttagctg tttgtttcaa atcatccatt
    23461 ttaggaagat aaacgattcg aaaatgatct ggctggttcc aattaaatcc accaccatgt
    23521 acaagtagaa tatgatgttc atgtaaaaag tccaaaacga atttttcatc atccaaaata
    23581 ttgaatcgct ttgtatcaat ttttgggaat atataaaaag cagcttttgg ttttacggct
    23641 gaaagaccag gaatatcatt gattgcatta tagatatatt ctctttgttc atagatcctt
    23701 ccgcctggca ggagcagctc atcgacactt tgataaccgc ctagcgcggt ttggataatt
    23761 tgctgagaca atacattgga acacaaacgc atggaggaca acatattcag cccttctata
    23821 tagcctttga cgtgtgactt atctccactt aggaccatcc agcctactcg aaatcctgct
    23881 acacgatgag atttggatag accgttcagc gtaacaacga acaaatcagg cgctaatgta
    23941 gcaatcggaa tatgttctag accatccatc actaagcgat catagatttc gtcggaataa
    24001 ataatcaggt tattttgtcg agctacttca acgatttctt ctaataattc ttttggataa
    24061 agtgccccag taggattatt aggattaatg ataacaatag cttttgtccg actcgttatt
    24121 tttgatttga tatcatcaat atcaggatac cattctgcct cttcatcgca aatataatga
    24181 acaggtgtgc ctccagctaa tgcaatagaa gccgtccaca acggatagtc cggcattgga
    24241 accagtactt catctccatt gtccagcaac ccctgcatac acatcgtgat caattcgctc
    24301 actccgttgc cggtgtagat atcattgatc gtcacattcg gaaaatgttt cagttggcaa
    24361 tattgctcaa ttgcttttct agcagaaaag atccccttgg aatctgagta gccttctgag
    24421 tcacgggcat tcatgatcaa atcacgaatg acttcgtttg gtgcttcaaa tccaaaaggt
    24481 gcgggatttc ccgtgttcaa ttttaaaata ctaatgccct cttcttgcat ccgctccgct
    24541 tcttctagaa cgggaccgcg aacatcgtaa ctgacacctt ctaatttgtt ggatttttca
    24601 aattctctca tcacttagcc aatccctcat ttcaaaaagt tagaactttc caaatttttt
    24661 gttatttact atttcaatat catactccat cctagaaaat tttgccactt atttaggaaa
    24721 aacgtaagta ttaaaaaaac acaaacaagc gttgagaact taattgtcat gatagtcatt
    24781 ccatagattc gctgcccaat ccattgcaat tccacaaatg attcctagca taaaaccaag
    24841 caaaaaacgt ccgaatgcaa gtccaatcaa tacacctaag atcattccca gtcctgaaaa
    24901 ttctccgtca tatttctcca tcttaataag tcctcccatt tttgagcttg acaactatgt
    24961 aaaacctcgc tatcattagt gtgttattat tacgcagatg tgttggaatt ggcagacaag
    25021 catgattgag ggtcatgtga gcgttagctc gtgtgggttc gagtcccatc atctgcacta
    25081 caactcgtga agttaatttt gcttcacgag tttttttgtt tgaacgtttc tttatgccat
    25141 tatatacata tcactgtatc ctttacaaaa agaacgtaca atcatgtaaa cagcctgagg
    25201 tgagtatatg aaggtcggaa acaagctact cgtagaaact tgcaagtgtt aaaacaatta
    25261 atcgaaaaac gagtaaaatc cctcacctaa tactaaagcg agggattttt tgtatattat
    25321 ctgtttatca ccgttattat aaaggtacaa ataccaagca cggttaatcc aaattgcata
    25381 aattcatttt tttgtacact catgcttttc attagctctt taactgccat tagtactaag
    25441 atggcgataa caacataaag tatatagtac gtccgcattc cggaagccca tactgtggga
    25501 gaaaatccca taattaacct tgaacaaaat cccattatca tcaaaataac taaaaaaata
    25561 gaagttttct tattgtcaaa acttaaataa attccaacaa ttaaacatag taataatgcc
    25621 aagactacta aagtagctat ccaagtacct ggataaaaaa gtgacagttt cgttcctaac
    25681 tctgtaaaga gattattcag gttactacta ctccaaatca ttgccctttt atttccattg
    25741 acgtaagtaa agctttgacc cattgtatta ccaaaataaa taatcaggtt taagaaaaac
    25801 ggtaatgcag tcaatatacg cacataatag ttttgacatt tcctatatgt tagaaggaaa
    25861 attaagaaaa atagcaataa aaataagata ttcatgtcta aaaaaaacgg ctttccaaat
    25921 gatgaaatac ctaaatctaa cttattaaga aagttgaaat ttttatattc aggaaaccat
    25981 ttattaattt catgtgcagc acgtaatgca ttccctggag ttgtcaaaga gaaaattaat
    26041 tctgctaagc ttattattga aaatactgat aacttataat tatatcgtcc attgacaatc
    26101 aaatataaac taactatact tgttagaaca aaaaaacagg cgttgacttg ttcttgatta
    26161 gttaaaaata tcaataaagg aatacttacc caatatattt ttctatttat ttcttctcct
    26221 cttaagagtt gaaaaaacgg ataaaaagtt agtaaactaa atgctactgg ccactgatag
    26281 ttcaaggtgg ttgctctcca accggtttcc cccattactg tcaatggtat taaacagtat
    26341 atagagcaaa ccaataataa atttttaaca tttattttct caaaaacata cttgcaaagt
    26401 aatactacaa ttcctaacat aatcgtagaa tttaataatt tccatagcat aaagtgttta
    26461 gaaaagaaca ttaagaatag ttctataata attcttgaac tccatgtctt ataatgttct
    26521 atcgaagcac ccaaatagcc aagttcatct aatctacttg cataaactac gtcatccgct
    26581 ctcatagtcg gcatatacat attaaagagt aaaaagatac cccaaatccc tattagtaac
    26641 aagatcagtt ctttgttatt cgttattttt ctattatgtt tgttcatttt tatactcctt
    26701 cttatatttc ctaatagagt ataacatagc tttaagcatt acttaaagat aacttaaaag
    26761 ttatctttta aatacttaat tgttaaatac cttatttgat gcaaaagaaa tctacgatag
    26821 tcaacaaaaa aattttcatt atatccagaa aaatttttct tagttaagga cctatggatt
    26881 gcagtaatgc agaattcgtc gaataaactg ccaaagacat acaatcatat tgcttttaaa
    26941 attgacgaac aagatataga ttcgtttgtc tcaaaaatcc aaatgttagg tttaactgtc
    27001 gaaccaggac gttctcgtgt gaaaggcgag gcttcttcaa tttactttta cgactatgat
    27061 aatcacctct tcgagttaca taccggtact ctccaggaac gtttaaaatc ctacaattcc
    27121 actacctgag actagtaatg actagtctct ttttatggcc tctgatcccc ccattgagcg
    27181 aatactaata gggcttcgaa ttgatctgtt caatctttaa gcaatatccc tcaaatgagt
    27241 ttggaaagtt tagtgattca tcacaaatac ttaaatacat gtagttatat atagattgag
    27301 gttcttgtga gcgtatgctc gtgtgggttc aaatcccatc gtctgcatcc atctttccaa
    27361 aacaagcggc taggacattt ttgtctcagc cgcttgtttt ctagtttatt ctttcatctt
    27421 gtcggacctt ttttcttggg tatagacttt tctcatattc taccacaatt ttgggtttcc
    27481 ctaacacatg ataggatctc acaacaaatt gctttctatt attataataa cctgtaacga
    27541 ctaacttcat cccttcgtct acttcagcta ggaagttcaa actatgggaa gcaatcaaac
    27601 aattgacccc atttaaactg aaacggatca acggtctggc actaacttgc aaagtacgga
    27661 tcttatctac tgttccatat tttttctcca taaccttcac ctcaatacca ttatacgaac
    27721 atacattccc tttgtaaaga agaaactctg ttttatcttt ttgacttttt gtctattacc
    27781 tttcttaaaa tcatattggc acttcctgcg aagatgaagg acatgtacta aaaaaaagag
    27841 gcagcagtat agattactgt tgcttcttta ctaatttagg tttacttgtt aagaaagatt
    27901 atttacgcaa atgttcttca acaatttgct gagatttatc agctgtatct tccacttcat
    27961 cttttgcttt ttctaacttt tgaatatatt gtttcaagct tgagttttca gcagttgctt
    28021 cgtctaattt cttttgtgta tctgttaact gagtttctac atttgttttt tcttgtgtca
    28081 gtgttgcgat ttgttgattc aaaccattta cagtattttg taattctgaa agttttgctt
    28141 gtgcttcttg tagtcttgct gtccaatctg cattcagatg attgatttca tcattttttt
    28201 ggttgatctc atctagtttg acattgattt cattttgttt gctttgtagt tgtgcatcct
    28261 tgctgactaa ttgactttct aagttttgtt tttctgctgc cgattgattt ttttggtttt
    28321 ctaattcatt tacttttgtt tggtattctt ggacatctgc ctttgaatct tgcaatgtct
    28381 gttctttttg tgctagtcga gcggtaagat ctgtaagcgc ttgctcttta tctgtcaatg
    28441 tatgatcaag ctgtgtcaga ttctcattga ttgtatcaat atctgtctct ccaccccaca
    28501 aaataatttc atttgcgtac cgcgtgcctg tgtagccaat tagacataga aatgcaacga
    28561 caatcccacc agtaataaat ttctttttca tttgcatagc tccttaatcc aatactttta
    28621 catgctaaaa gtaagtgatc tcaaacacaa tgtcaagcgt ttttaaatta catgtgtaat
    28681 tttaatataa atactatcaa atactcattt aatcctcctt ttttatctat ttaaaaaatc
    28741 ttttttatag agaaaaatgc aggttaatac tttcttaaat aaatatttat ggtgaacaaa
    28801 aacaaaaaag caagttttat taaacgtaac ccttttcatt tcatagatta ctgtatttat
    28861 tacaaaaaac g
//
LOCUS       DAFTHM010000028        25765 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFTHM010000028 DAFTHM010000000
VERSION     DAFTHM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.028"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(102..1076)
                     /locus_tag="L7C88_001213"
     CDS             complement(102..1076)
                     /locus_tag="L7C88_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBP9558056.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(1057..2940)
                     /locus_tag="L7C88_001214"
     CDS             complement(1057..2940)
                     /locus_tag="L7C88_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBP9558057.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(2958..5183)
                     /locus_tag="L7C88_001215"
     CDS             complement(2958..5183)
                     /locus_tag="L7C88_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBP9558058.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            5298..6332
                     /locus_tag="L7C88_001216"
     CDS             5298..6332
                     /locus_tag="L7C88_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9558059.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(6399..7412)
                     /locus_tag="L7C88_001217"
     CDS             complement(6399..7412)
                     /locus_tag="L7C88_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBP9558060.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(7490..7678)
                     /locus_tag="L7C88_001218"
     CDS             complement(7490..7678)
                     /locus_tag="L7C88_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBP9558061.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(8118..8246)
                     /locus_tag="L7C88_001219"
     CDS             complement(8118..8246)
                     /locus_tag="L7C88_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBP9558062.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(8249..9622)
                     /gene="rlmD"
                     /locus_tag="L7C88_001220"
     CDS             complement(8249..9622)
                     /gene="rlmD"
                     /locus_tag="L7C88_001220"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBP9558063.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(9733..10788)
                     /locus_tag="L7C88_001221"
     CDS             complement(9733..10788)
                     /locus_tag="L7C88_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBP9558064.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(10798..12228)
                     /gene="gatB"
                     /locus_tag="L7C88_001222"
     CDS             complement(10798..12228)
                     /gene="gatB"
                     /locus_tag="L7C88_001222"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBP9558065.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(12225..13697)
                     /gene="gatA"
                     /locus_tag="L7C88_001223"
     CDS             complement(12225..13697)
                     /gene="gatA"
                     /locus_tag="L7C88_001223"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBP9558066.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(13697..14002)
                     /gene="gatC"
                     /locus_tag="L7C88_001224"
     CDS             complement(13697..14002)
                     /gene="gatC"
                     /locus_tag="L7C88_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBP9558067.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(14108..16144)
                     /gene="ligA"
                     /locus_tag="L7C88_001225"
     CDS             complement(14108..16144)
                     /gene="ligA"
                     /locus_tag="L7C88_001225"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBP9558068.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(16161..18395)
                     /gene="pcrA"
                     /locus_tag="L7C88_001226"
     CDS             complement(16161..18395)
                     /gene="pcrA"
                     /locus_tag="L7C88_001226"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBP9558069.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            18550..20109
                     /locus_tag="L7C88_001227"
     CDS             18550..20109
                     /locus_tag="L7C88_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBP9558070.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(20220..22151)
                     /locus_tag="L7C88_001228"
     CDS             complement(20220..22151)
                     /locus_tag="L7C88_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBP9558071.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(22169..23083)
                     /gene="pfkB"
                     /locus_tag="L7C88_001229"
     CDS             complement(22169..23083)
                     /gene="pfkB"
                     /locus_tag="L7C88_001229"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBP9558072.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(23080..23832)
                     /locus_tag="L7C88_001230"
     CDS             complement(23080..23832)
                     /locus_tag="L7C88_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBP9558073.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(23991..24200)
                     /locus_tag="L7C88_001231"
     CDS             complement(23991..24200)
                     /locus_tag="L7C88_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558074.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(24211..25539)
                     /locus_tag="L7C88_001232"
     CDS             complement(24211..25539)
                     /locus_tag="L7C88_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558075.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
BASE COUNT         6946 a         5523 c         4676 g         8620 t
ORIGIN      
        1 caaaagtatc tgagaacttt tttactctct tgttcatgac atatagaata aagcagcttt
       61 gtcttgtaaa ctccgttttt caaataataa tctaaagatt gctactgaat aataaagccg
      121 atttcatggt cctcttcgct gctgattcgg taaggtgact caacatccgc tccccagcta
      181 ttgatacccc cgactcctct tacttttgca aaaatcgtaa gaaccgttcg tctttctggc
      241 ggtagttctt ctatatgtgt tgcctgttcc agttcttctg ctttgaatgg taaagcggaa
      301 aaagcaaatg gcgtatcctg ctgttcaaat cgcaacgaaa aatcttcttg atctttatcc
      361 gtattatcca acgtttgatt tcttgttagt tctacccatt tcgtttccat atgcatgccg
      421 cattcttggg gaacaaggta tggggaaacg gggagtcctg ccactttata aataccttcg
      481 acaccaccag ccatccgatc cggatatgtt tcccctgata ggccttcata ctcaaaaaat
      541 tttgctttcg ttggcataat gaaccttaaa cccaatgcgg gtaattccgg taatcctttt
      601 tgtccataat aatgcatatt gacaagcatt ttaccctctc cagcgatttg gtaggaaatt
      661 gtcacttggg tttttggtac tgtgttgatt tccagtgtaa aaatgatttc aaccgtttca
      721 gcgtattcat tacttgaata ttgattattt actggagcaa tcggcaaatc gatcttttta
      781 ttgtccacca gtacttctat ttctttgact tttggataca atccggctcc taaccacata
      841 ccggatttaa atccaaatcc gctacctctg tcattatcgg tcgttgctcg ccaaaaaact
      901 ggaagtgttt cccggtatag ccattctttt ccgtttttat tgagcgattc cagtccgcct
      961 cttgtataag aaaaaatata atgcgtattc cccgatttga cacctaatgt acagtcgccg
     1021 aagacgattg caactttttc cgtatccata tgacttttat ttactgtatt tttcataata
     1081 atatcttacc tcctgcatgg cgggtttttc ttgtccatct gcaaaaacga tcccattccc
     1141 tgagaattca tagtcacttg gtttatcgtc aaagtcaccg ccatagcgca tcacttctct
     1201 gcctgtgatt ggatcagtca cttggatcgc ctgatcttta aaatcccata tatagcctcc
     1261 ttggtacatt tcataacgat caagcaacgt catgtaagaa tccattccac ctaacgaatt
     1321 ccccatgtca tgcatatatt cacataagat gaacggtttt tccgctttat tttcaaggta
     1381 gtcaatgatc tcttctggtg gcgcatacat gcagcttttt acatctgaaa tcgaatcttc
     1441 gaatgctgga tttggaaaat tcccttcata atggacaagt cgatcggggt ctactttttt
     1501 gaagtaatcg ttcatttgtc gaatgttttc ttccgcataa gattcatttc caagagacca
     1561 aaaaagaata cttggatggt tttttaatgt ttcgaaattc gtttttgctc gatcaagaac
     1621 agccgcctgc cactgaggta ctgcacctgg tacgttgtaa gaaggctcaa atgcgcccat
     1681 tttttgccat gagccatggg attcgaggtt cgtttccgcc atcacatgga ttcctgcttg
     1741 gtcgcataaa taataccaag tgatctggtt ggggtaatga gatgtccgta cgccgttgat
     1801 ctttgcattt tttatgatag ccaaatcttt ttccatatct tctatagtga tggcgcgtcc
     1861 ttttttcgga tgccactcat gtcgatttac cccgttgata atcatccgtt ttccattgaa
     1921 gtagatgatt ttatctttga tttcgatttt acgaaaaccg aaggaatagt caatatactc
     1981 cgttactctt ttttcttcgt ctatcgtctc caattcaagc ttatataaat tgggctgaaa
     2041 atgcccccac agtgccacat tttcaaatcc atcgatgcga atcgtcattt gctcttttaa
     2101 cggatattgc tgttgataga tttccttccc atcaggatct agtatcgcta cattcagctg
     2161 actgtttttg gctacttgct caaaagacaa atctacttca agtttgccat tttgacattt
     2221 gtcatctaag cgaggtttga tccaaagatc ttctaaatgg ttttgtcctc gagcaactaa
     2281 gaagacatct ctgaagatcc caaaaaatcg gaaaaagtcc tgatcttcca agaatgcagc
     2341 tgtacttctt ttgtaaacct ccacagctag aatattttct tcttccaaat aaggtgttaa
     2401 atcaaattca gacggagtga acgaatcttc ggcatacccg ataaaatgac cattcaacca
     2461 aataaacatt gcttgttcta caccagcaaa atgaatcgag atttgttttc cctttagacc
     2521 ttcttctaat cgaaaagtcg tcaaatacga accaaccgga ttgtctttag cagctgaaaa
     2581 gatcccttcc gcctctttct cagggcttgt cgtgaaaggg ggacggcgaa atacatgtcc
     2641 ctcccacgga tacatcgtat tgatgtaatg gatcttgtca taatttgcta attcaatatg
     2701 actaggaaca gtgatttcat caaaagaaca ggcatcaaaa tcttttttat aaaatgtttt
     2761 tggtcgtacc gaaggatttg gcgaataaca aaaacgccat gatccattta aagactgttt
     2821 aagggaggat gtggtttcta cttcttccct tgttgcataa caaacatgat cgctatgtgc
     2881 atttgattgg ttcactctaa aaacttgtgg atcatctaac cattttatat ttgctttcat
     2941 acttttttcc ttctctctca taactttttg aaatgaagca gttctgtttg gaaatcacct
     3001 tgaaaatcgg ggaagtaaag tccaactgtc atcaattcgg cccccgaaaa tatccgcttc
     3061 gaggtctgtt cctgataaag tgcctcatca tctaacccca tcagatatac ttcatggaac
     3121 gctggttgag ctgaagctag tatcctccct aaaaacacaa tagcttcatc ttgtttagga
     3181 gacacaaaca tccatgcggc aatattttct tcaaaaggac tcgccaaacg ataataatgg
     3241 ccatactgga tcaccggacg aatcgtttga taggatataa tttggtcttt tacttgcttt
     3301 ttttcttcag gagacagctt tgtcaaatcc agttcataac caaaaacagc gctcatagct
     3361 gtttctcctc ttgttttcaa cgaagtagat ctgtcggtct gatgatttgg tacagctgat
     3421 acatgagctg tgatggacga aatcggataa gcaaggcttg ttccatattg gattttcata
     3481 cgctccactg catccgtgtt atcacttgtc catgactgcg gcatataata aataaacccg
     3541 gcatcaaacc gtccacctcc accagaacag ccttcccata agatttccgg ataatcagtt
     3601 gtcaaatgtt caagtagttc ataaagcccg agcatataac gatgcgctac ttctccttgt
     3661 ctctgtgggt caagggtaat cgaatagaca tctgaaagcg aacggttcat atcccatttg
     3721 atgtagtcaa gaggaatcgt atctaaaatc tttctcattt gtttctcaat cgtctgccga
     3781 acatctaacc ttgtaaaatc cagtacatgt tgtgatctgg aagcagaagg cattctacct
     3841 ggctcctgca taagaaaatc aggatgtgtt cgatacagtt cagaatcaac cgagatcatt
     3901 tcaggttcaa accataaacc aaatttcaat cctttgctat gagcataatc tgctatttca
     3961 cgtaatccat ttgtcaactt gccttcatac tcgaaccagt ctcctaatga agaattgtcc
     4021 gcatctcttt ttccaaacca gccatcatct aatacgaaca tttcgatgcc tagctccttt
     4081 gcttcatcaa tgatcgcctt gattttttca ctattgaagt caaagtaagt ggcttcccag
     4141 ttattgacca gaatcggccg ttcagcaaat tgatgacgac ctcttgcgat tctttcacgt
     4201 agcaactcat ggtggatctg actcattttg ttcaatccct gacttgagta agaaaggatc
     4261 atttcaggtg tttgaaaaga ctggcctgca ttcaattccc acgaaaaacg atggctgttg
     4321 atcccaccga cgactctcaa ttgattgatc tgatcttttt caagttcgaa agaatggttg
     4381 ccggaataaa caaattgaag tccgatcgct tctccagtat tttctgtcgt atgatgatga
     4441 actaaagcaa taaagttatt catatggtga ctgctcgttc ctcgacggct ttcaaatact
     4501 tttgttccag ataaaacaga ttgccgtgaa atctgtcttt cattgacatg tgctcctggc
     4561 aaagcaatga cttcatcaaa tcgcctagta tgggcaaagt ctagctggaa actagccgct
     4621 ttttctagtt tgattgtttc tccggtttca tttcttatct ttacagatcg tgtgatcact
     4681 gctctatcag taaatatggt atagaacaaa tcgaaataaa tcgctgtttc tctatcctta
     4741 agtgaaatca ccaacgtttg tgcctctgac ttgtccatca cataagtttg aggcaagcct
     4801 tcgatctctg gcttcccatc tgtaatataa tggctgtcat atctcagatc cagtaagtct
     4861 gatccattct tgcgctgaat gatcgatgcg ggcgttcgaa agtccatgct gccatgagaa
     4921 gagtattctt gcggtagtgt atctttcgac agagaccggt caggatttaa gggaacattt
     4981 cctgaaaatc cacgatctct tcggggataa tttttattgt ctttgtactg cttgactggt
     5041 ttgccaaaat aaatatgcgc caatacattg ctttcttcta tctttatcag ataagaaaga
     5101 aatgtatttc gtaaatggaa gactcggctc ttttcatcaa ataagatgaa atttttatct
     5161 gtttttctat gcgtaatatc catcatttca ctcccaacaa aacggaaacc gtttactttt
     5221 ttttataatt cctgtatact gtttactaaa caattttgtc aataaaaatt ttttattttt
     5281 ttgaggagtg tgtaaaaatg gttggaatta gagatgtcgc acgaaaggca aatgtctctc
     5341 ctgctacagt ttcccgtgtg ttgaataacg atcagacgat ccatgtggct cagactactc
     5401 ggcaacggat agtagaggca gctgctgcgt tggattatga catcagtact cgtaaatata
     5461 tcaaaaagag aatgccttcg attggtgtga tctctacgat cggcaaagcg agcgaagaac
     5521 aggatatcta ttacaaacat ttgcgagtag ggatggaaga agaagctcga cgtctgcatt
     5581 tagggatgaa tcgaatctat aatctatctg ataatcctaa acaatgggaa gatctagatc
     5641 agttaggtgc ggtgatcgtt gttgggactg ttacgaaaga atcgattacc gccttgttaa
     5701 aacaaaacat gcaaatagtc gtcgtggata accctgacat ccagcaagag gtcgatatgg
     5761 tgtatgcaga tcttgaacgg atgactaaaa ccgtactgga attgttctta gaaaatggtc
     5821 ataaaagaat agcctatatc gggggatata aagtcgatat ggatgaattc ggtgggaagc
     5881 agatttctat aaatgaaaag aggatgcgtg cctatcagca ttttatgatc gatcatcact
     5941 tagaaaaata tatgtcttat catctaggtg gctggacaga aaaacaaggt gaggtacttg
     6001 cgactaatct attagaaaat gaatcccctc ttcctactgc cattcttgtc gggagcgatc
     6061 caatggcaat tggtgtctat cgggcattga aacaaaaaaa tatccaaatt ggagaagaga
     6121 ttgttgtagc aagctttgat aatatcgaga caatcgcaaa cctctcccct ggcttgacca
     6181 gtgttcaaat caatgcgaaa tcaattgggc aagcagctgt tcgaatggca ttggagcgaa
     6241 ttgacggtat acgggacgaa ccaatcattt tgacttatcc tgcacgattg attgttaggg
     6301 aaagttttat cccaagaaca aaaaggtatt gaaagagagg ttgtgaaaag ccgcttcgtt
     6361 tcttcatact caaaacgaaa cggctttttc acaacctctt acttatactt attcacaaaa
     6421 tccaatgtct gctggtaaca attttgcgat tcttttagcg tgtaatcaaa ttggtattca
     6481 tgggtaatct ctttttttgt atctgtataa aacaaggatt gcacgggtac ctttaattct
     6541 gtcaaccgat tttctaatgc ttgaccttgc tcctggaatg agtatgcatt tccgtcagtt
     6601 atatacgttg gcggaaattc cttagaaaca tggtcagcca cactagcttc tttcaattgc
     6661 tcactcgttt tccaatcttt tgttccaatc aacgaccacg caacggtttt gacgaaaaac
     6721 ttcataaatc gatcatccga atgctgctgt gctgttagct tcaaatcaac aggtccgcaa
     6781 taagaaatgg ttcctttcag actatctttt ggaagtagct gtttgatttt catttgttta
     6841 gcatacgcat cattcgtttg tatagctgca tattgcaatg cgatttgtga acctgcacta
     6901 tctccaccaa aaaataattg ttccatgtct agcaatttgt cgtctttttc ttcagctaat
     6961 aaatctttga tcagttcatt cacttgaaga acttgattag ggtattctga atcaggcgct
     7021 aattcataat tcatcgcaac cactgcgatg ttggcgtctg aaactaattt tgtcgcaaat
     7081 tctttgacac ccgatttatc tccgccgacg aatcctccac catgtaccca aaatagaaca
     7141 ggaacaggcc ccttgctgtt ttttggatag tagatgtcat aagtattctc tttatacttg
     7201 gactcatacg tcaaatctgt ttttttcgcc acgttttttt ctgcttgatc gaacgttttt
     7261 ttatcagtga tttgaacagt atttgaaaac atatggttga tcaagaatgc tccaggtctg
     7321 ggggaaagct ggaaggcaag aaagattgca aacgcgatcc caagaatgat tccgaagaac
     7381 catccgataa atttaagaat tttctttttc ataaggctcc ctcagtagtt agtattaagc
     7441 attctgatta taccatagtg ttatttccta tcaagctctc ctagatgatt taatgatttt
     7501 ccccaaactt cttctgcaat gcttttgaca aaagaaattt tttccattgt tcttcaaaca
     7561 aaacattttc ttcttctgtt gaagcaaatc cacattgagg acttaagcac aaacgatcca
     7621 aaggcagata tcgtgtcgct tcgtagatcc ggtcaatcac ttgctggtgc tcttccattt
     7681 cgccattttt cgttacagtc aaaatctaag acaactaatt tatcttcaga gactttctct
     7741 aaaagaacaa aactcccagc acgttcacta tcgtattcta aataataggc acggacattt
     7801 tcttgagtaa aataatgggt ctgctacgtc gtcatccccc ctgatgccgc caaaatcgaa
     7861 taataatttc cgcgtcaaac atgtatattt agtgttgaat catttgagaa tatgaaaata
     7921 aaaatctttt tgatcaatca gttaatcaaa ttgaaataac gaaaaatctg agacagaatg
     7981 acgttcattc tgacccagat ttgattttgc acaactcaac agtccttatt ggcaaatcgc
     8041 caaaataatg tagactaact aaaaagacta agaaacaata acaaaagtta acacttctta
     8101 gtctttcttt agcacgtcta tttattaaag attttagggc cttttctcat gtttttacga
     8161 tcattcttag gtgtttccat ttgtttggat cggcctccac cttgtttctt tttgatcaat
     8221 tctttcattt tttctttttg gtccattttt attctccttt aacgaatgaa gcgactaatt
     8281 cgatatgatg ggtttgcggg aaaagatcta caggctgaac tttcttcacg gcataacctg
     8341 cttctgcaaa taacttagca tctcttgcaa aagttgccgg attacatgag atatagacga
     8401 ttcgttctgg tgacatttcg attgctgatt caataaaatg atgatctaat ccttttcgtg
     8461 gagggtcaac tacgatcaca gatggtttga tccctttttc ttgccatttt ttcataactt
     8521 tttctgcttt tccgacttca taatgaacat tttcgatttt attatttaaa gcattgaact
     8581 gtgcatcttc aattgcttct ggaataactt ccatcccata caccttatcc actctgtctg
     8641 ctaaagacaa gccaatcgta cctattcctg aataagcgtc gatcacaatg tcttttttat
     8701 ctaactcggc aaactcgatg gctgtttggt acagatactc tgcttgttga gtatttactt
     8761 gataaaatga ctttgctgag attcgatagg tttttcctaa tagctgatct tcgatatagt
     8821 ctctgccata taaaactttt tctttgtctc ctaaaatcac atttgttttt tcttcattga
     8881 tattttggat gaccgaaacc acttctggca attcttcatg aatagcttca gcaatttcct
     8941 tggatttaaa gaatttttct ttacgagtaa ctaaaacgac catcatttca tgggaataat
     9001 gaccacgacg gataatgatg tgacgaagct gtccttcatt tttttcttca ttatatcctc
     9061 gtacttggaa ccgttgcaag atatctctga ctactttgat tgcttgatcg atgacaggat
     9121 cttggatata aaaatcttcg atagggacta gatcatggct attctttttg taaaaaccgg
     9181 tggctaactg tccatcgata cggcgaacag ggatctgtgc tttattacgg tagccgaatg
     9241 gttctgccat tccgaccgtt ggaagtacag gaacttctgg catcttagca atcttcgcca
     9301 ttacatgctc tacttgtttt tgtttgaaga caagctgttg ttcatacttc aaatgggcta
     9361 aaggtgcgat acctatgcga agtaatgcat tgttttctac aggctgacga tcaggtgatt
     9421 gtgtaataaa tgtttcgact tttccatatc caaacttatt gcctgctttt actactagta
     9481 tttctacttc ttctccaggg agtgcatttt cgataaataa tggataacca tcgatttttg
     9541 ctacccccat tccttcataa ctcaagtcga cgatttcgac tgtatatcgt tcgtttttct
     9601 ttactatttg ctgttctgtc atattttgct cctttaagcc tatttttcaa tcctactgaa
     9661 ctctactata aatcagctaa ttacacaact aaaaccggca ctgaccttac tacgttcagc
     9721 accggctttt gattaattct tttgattagg tgtttcgtct gctatttttc cgtcaccgtc
     9781 gatatcttca tccgttaaac gttcgacttc ttttacgaat tctttgctga caacctctaa
     9841 ttcttcttca tctgtacctg tgattgcttc atcaggaatc tgatcggtat tggcaaagaa
     9901 ctcaatgtgt tgatgaagat tttggaaatg catcggtgct tccccgccgt attcaccatc
     9961 taagttgatc attactggtc gattgatatc atcttctgtt tcaacgaaca aactgcttgt
    10021 tttggtatag attattcttg gatcatcgac atgtcgaccg ccattcagca tgagtgctgc
    10081 aatatgcaag atctcaaaga tatttgctgt cttcacaatg attaaagaaa acttcccatc
    10141 atccaatttg gcatctggcg cgatctgttc gaatcctcca acagagttcg tcagccctag
    10201 gaaaaacatc gaagcatttc cgatatattc cccttcatca tacttcaagc gcattttgat
    10261 tggctttact cgagggagca tctctgctcc tttcgcaaga taagcaagat aaccaaaaat
    10321 actctttagt tctgatggaa cttcataagt caattctgtc aaatagccac ctgcagcgat
    10381 attgatgaag taactgttat cagaaaggcc gatgtccatt tttacggttt ggtgtttttt
    10441 tatcacttct gctgctgctt taatattatc tctaggaatt tttaatgctc gagcatagtc
    10501 gttcgttgta ccagctggga tgatggccat tttaggacgg tgttcaagcg gagcgattcc
    10561 attaaccact tcgttgattg tgccatcgcc accagctgcc actactagat caaaacctag
    10621 ttctgcgact ctacatgctt cattcttggc tgaatctggt tctggtgtag ttgcataggc
    10681 gctggcttca aatcctgctt cttctaatgc ctgtaggata tccgccaaat tttttttcaa
    10741 taattctttt cccgaggtgg ggttataaat tacgcgtgct tttttcattt tcagcctcta
    10801 tcgtttcgct aattcatctt taagtagctt attcacgaca ccaggatttg cttgtccttt
    10861 agttgctttc atgatttgac cgactaggaa gccaaccgca cgatcttttc catttttgaa
    10921 atcatcgaca gattgttggt tgttatccaa aatttcatta atgattggca gtagtttgtt
    10981 cggatcagat aattgcaccc aaccattttt ttcaactact tcttgggctt ctccgccatt
    11041 tgtgatcaat tcacggaaga cttttttggc gatttttgag ctgatcgttc catcggcgat
    11101 caaacgaatc attcctgcta agttctcagg tgtcaatttt gtctcagcta attccagttt
    11161 ctcactgttc aagtaagcag aaacttcacc catcaaccag ttagatgctt gcttggcatc
    11221 tgcaccattt tccaaaacag cttcaaaaaa atcagacatt tcttttgtaa gtgtcaatac
    11281 cattgcgtca tactctggaa gtccaaactc acggatatag cgttcgcgac gagaagctgg
    11341 catctcaggc aaactagctt ttactttttg aatccattcg tcatcgatca cgaatttcgg
    11401 gatatcaggc tctgggaagt aacgataatc actagaccct tctttgacac gcatcaaaac
    11461 tgttttattc gttgtttcgt caaaacggcg tgtttcttgt tggatttctc ctcctgaaag
    11521 aagaactttt gcttgacgtt tttcttcaaa agctaaacct tttttcacga aagataaaga
    11581 gttcaagttt ttcaattctg ctttcgtacc gaactcttct tgtccataag ggcgaagaga
    11641 aatattggca tcacagcgca tagagccttc ttccattttc acatcgctga cttctgtaaa
    11701 ttggataatt gatcgcaatg cttctagata agcgtatgct tcttctggtg aacgcatatc
    11761 agcttcagaa acgatttcga tcaaaggcgt gccttgtcgg ttcaaatcaa cgtaagaata
    11821 accgccaata ccatgcatgt tttttccagc atcttcttct aaatggacac gttcgatccg
    11881 gatttttttc tttttacctt ctacttcgat ttcgatccat ccgtcatgac cgattggttg
    11941 atcaaattgg gaaatttgat atgcttttgg attatctggg taaaagtaat ttttccggtc
    12001 aaaatgagta tctttagaga tttcacagtt taatgccaaa gctgctttca tcccgaattc
    12061 cagcgcagct ttattcatta ctggcagcac gcctggataa ccccagtcga tcacgtttgt
    12121 attgctgttt ggttctgcac caaaatgagc tggcgctgga gagaaaattt ttgagttggt
    12181 ttttaactcg acgtggactt ctagtccaat gactgtttca aaattcattc gtctttccct
    12241 cctaaaatag ctggttgttg tttatggaat tctgttgctt gttcaaacgc atatgccgct
    12301 tgatacatcg ttttttcatc aaaataatta ccgatgatct gcaatccaac tggtaatcct
    12361 tctgataaac ctgccggtac agacatacct ggaagtccag ccaagttgac agggatcgtt
    12421 aagatgtcac tcatgtacat tgtgattgga tcgttaatgt tctcaccgat tccgaatgca
    12481 actgttggtg aagatggccc gatgatcaag tcataatctg caaagacttt ttcaaaatct
    12541 cgtttgatca atgtacggac ttgtcctgct tttttgaagt aagcgtcata ataacccgcg
    12601 cttaaggaga atgtacctaa catgatacgg cgttttactt cttcaccgaa tccttctgaa
    12661 cgtgagttga catatacatc atctaatgat ttcacatttt cagagcgata accgtagcgg
    12721 ataccatcga atcgttgcaa attggaactt gcttctgatg aggcaatgat ataataaaca
    12781 gccacaccgt attttgaatg aggcaagctg acttcttcca caacagcacc taatgaacgg
    12841 aatgtttctg ctgctttcaa tacagcttct tttacgccag gggccacacc ttcgcctaag
    12901 tattctttag gtaaagcaat cttcattcct ttgatgtcgc ctgtcagtcc ctctgcaaaa
    12961 tcaggaactg aaacgcctga agaagtaccg tctttttcgt cataaccgct gatagctgtc
    13021 aatgctaatg cattatcttt caccgtacgg gtcattggtc cgatttggtc aagagatgaa
    13081 gcaaaggcaa tcaaaccaaa acgtgagaca cggccataag taggtttcat ccctacgatg
    13141 ccgttaaaag ctgctggttg gcggatactt cccccagtat cactacctaa agaaactgga
    13201 atttgtccag ctgcaactgc tgctgcagaa ccaccagaag agccaccagg tacttttgtt
    13261 gggtcccaag cattttttgt tttcttgaaa taagaagttt ctgtacttcc acccatagca
    13321 aattcatcca tgtttagctt accaacaggg atcatatctg cttgatagat tttatccatg
    13381 accgttgcat cataaattgg ttcaaaattg taaaggatct tagatgcagc ggttgtcaag
    13441 atatcttttg ttacgatatt atccttgata ccaattggaa taccagcaag gacgttgctt
    13501 tcatcaatcc ctttttcatc taaagctttt gcctgttcca atgctttttc ttcgttcaat
    13561 gtaatgaatg cctcgacctc aggctctgtt tctttgattc gttcaaatgt tgtttttgtc
    13621 aaatcttgta cagtgatttc tttcgataca agcatatgat gcagttcttc tagagaacga
    13681 ttgtgtaatt ctgtcattat gcgccagcct ccccattatc gatgattgcg ggtactttga
    13741 taaagccgtc ttctgtttcc ggcacatttt tcaataattc atcgcggttc catccagctt
    13801 gcgcccgatc ttgtcgcatc acgtttactg tttcaaccac attcgacgta aatggaacac
    13861 cttccgtatc tacttcttcc agcatttcaa ccatatcgat gattttacct aattggtcgg
    13921 taaaacttgc aagttcttca tctgcgaacg caagttttgc taatttggca acgtgtttca
    13981 cttgttcttc actaatcgcc atactacccc ttctttctaa acgagttaaa aactttgctc
    14041 tctattttaa cacaagagtg ccgtgtctga aattgtttat tgaaatttgt ctgaaaaaac
    14101 tcatttttca ttcttctact gagcgacttt tagccaatgc atctgccatt tgatcttctg
    14161 tccaaacttc gattcctaat tcttgtgctt tggtcagctt gctgccagca tcttctcctg
    14221 ctaccacgat atccgttttt ttcgatacgc taccagtcac tttcccgcca agattttcga
    14281 tcgtctcttt tgcttcttca cgagtaaatc gtgttagttt accagtaagg actactgttt
    14341 tttctttaaa aggagactcg acttcttgca attgggcatt tcgaagccct ttgtattcga
    14401 aattgacgcc tgcttgtttt aattcattca tcaattcatg gacttcttcg ttactgaaat
    14461 aagtgactac actgtcggca atgatatcac cgatcgtatc aagcgcaata atcgactcat
    14521 agtcactttt actcaatgtt tctagatcac cgaaatgttc tgctaaaatt tttgctgctt
    14581 tcgctccgac atgtcggatt cctaacccga aaatcaaccg ctcgaccgaa ttatctttgc
    14641 tgttgtcgat tgctgtcaaa atattatttg ctgatttttc ttttattttg tccaacgtca
    14701 ataactcttc ttctgtcaat ttgtaaagat cagcaacatc tgctactagt tttttatcat
    14761 acatctgttc tagtacgcgc ggccccaacc catcgatatt catcgcattt cttgaaacaa
    14821 agtggttcaa accttctttc atttgagcag ggcatttagg attgatgcac cgtaaggcta
    14881 cttcttcatc caaatggaca agttcacttc cacaaactgg acaatgtgta ggcaattggt
    14941 attcttcgct gtctttaggt cgtttatcta acacgacttg cgaaacttct gggatgatgt
    15001 ctcccgcttt ataaatcaga actgtatctt tcaagcggat atccttcaac ttaatataat
    15061 caccgttatg caggctggca cggcttactg tcgttcctgc tactcggact ggtgtcatga
    15121 tagctgttgg cgttactacc cctgttcgac cgactgtcca ttcgatgttt tcgattagcg
    15181 tttcaacttc ttctggcgga aacttgtaag ctgctgccca tctcggtgct ttgatagtaa
    15241 aaccaagttg atcttgtagc gagaattcat tcactttgat gacgattcca tcgatttcat
    15301 agggcaaatc cacacgtttg tcatgatatt cttcaatgta tgaccacact tcatcaatcg
    15361 aatgacatag acgtttttcc cgattcgtgt ggaatccaat tttttctagc tcttctagcg
    15421 catcatactg ggtttttgct tgcataggac cgaaatcagc tactgtgtat aaaaaagtgt
    15481 ccagatttct tttcgctgtg attttagaat ctaactgacg caaagaacca gctgcggcgt
    15541 tccgaggatt cgcaaagata tcttttccct ctgcttctct gtcttggttc aattggacaa
    15601 atgaccgttt tggcatgaaa cattcgcctc ttacttcgat gttcattggt tcttttaatt
    15661 tgattgggac cgaccggaca gtttttaggt tttcagtgat gttttctcct acagttccat
    15721 ccccgcgagt cgcacctctc acgaaatttc catcttcata acgcaaagaa acggaaagtc
    15781 catctatttt tagttcacag caatagtcaa ctacacgtcc cactgctttt tgtacacgtt
    15841 gatcaaaagc tatcagctct tctttgctga aaacgtcgtt caaactgtaa agcggaatat
    15901 catgagtgac tttttcaaaa ccttctaata cttttccgcc tactcgttga gtgggagaat
    15961 cagacgtgat caaatcagga tattgttcct cgattgctac taattctgcg tattctttat
    16021 cataaacata gtcttccact gttggtttat cttctacgta gtattcgcga gaccattggt
    16081 tcagtcttgt acgaagttct tctgctcgtt tagcagcttc gtcaatcgtc atttcatgtt
    16141 ccatcattta ccctccacta ctaagctttt tcaattggcg caaaggcagc caaaagacgt
    16201 tttactcctt gacttgggaa agccacatct agttctagat ccttcgacgt cccgcttact
    16261 cggacgactg ttcctagacc ccattttttg tgtttgactt tatctccagg tttccagctg
    16321 ttattttccc ctccagtagc acttttagag ggaacaaccg ctgtctctgg ctgtttatag
    16381 ctatatgctg tttttttagc gaatacaggc gtttttttag gcgtaggacg catgccttcg
    16441 atttccagta actcctgatc gatttcttct acaaaacgag aaggtcggtt atattgcgtc
    16501 cgtccatata atgttctgga gaaagcattt gttaaataca acgcttcttc tgctcgcgtg
    16561 atccccacat atgcgagacg gcgttcttcc tccagttcgc tttcttccat caatgctcga
    16621 gataaaggaa aaaccccctc ttctagacca atcaggaata caactggaaa ttctaatcct
    16681 ttggctgcat gcaaagtcat caatgtcact tgggaagcat cttcttctaa attgtcaatg
    16741 tcggaaacaa gtgccagatc atttaagaag accgttagtt tttcttctgg tgcatcagcg
    16801 tcttcttcat tttgctgttc gaattgtttg tcgaattctt gtgtgaccgt taaaaattcc
    16861 tccaagtttt cgatgcgtgc ttgtgcttct aatgtatttt ggatttttaa gtcttctaga
    16921 tatccgctac gatccaaaac ctctttcgtc aattctgtca ctgtcaagta tgggatcatc
    16981 tgagtgactt cttggatcat ctctccaaat gcacctaatt gctgtcctgc ttttccaccg
    17041 atatttgcca gatccacatt ttgcgctgct tcaagcagtg gccattcatg aagagaagca
    17101 aaactgcgta gtttttcgat agatcctggt ccgatgcctc gtttgggcga attaacgata
    17161 cgctcaaaac tgattgaatc ttgaggattt accagcacat tcaaatacgc taaaatatct
    17221 ttgatttctt tacgatcgta gaacttgtgc cctccaacca ttttataagg aatatttgct
    17281 ttcaacagag tttcttccat tacacgagat tgtgcgttcg tccggtacaa gatggcaaag
    17341 tcgccgtaat tccgatgatt gcttcgaatc tcttcttgca tccggtctac gataaaacgg
    17401 gtttcgtctc gttcattatc tgcacggtag taagtgatct tgtttccttc tttgttttct
    17461 gtccacaagt tttttggttt tcgattgcta ttgttttcaa tgacttggtt tgctgcgcta
    17521 aggatgtttt tcgtggagcg atagttttgt tctagcaaaa ttactgcagc atctggataa
    17581 tctttttcaa aatccaagat gttctgcata tctgcaccgc gccagccgta aatactttga
    17641 tctgcatctc ccacgacgca caggttccta aatctacctg ccaataaatt gactagcgta
    17701 tactgtgcgt gatttgtatc ttggtactca tctacatgaa tataatggaa tttgttttga
    17761 taatacgtga gtgaatcagg atgttcttca aataatcgaa tcgtattcat gatcaggtcg
    17821 tcaaagtcca tacattgatt atattgaagc tctttttggt aagcagcata acattttgcc
    17881 gcaatctctt cgtaataact gccttgcatt tttgcaaaat cctgaggggt ctgcaggctg
    17941 ttttttgctt gagagattgt tcctaatata cttcgaggat catatttttt cggatcaatg
    18001 ttcagttctt ttagtatccg tttcatcaag gtcagctgtt cagaagaatc gatgattgta
    18061 aagttccggt tatacccgat aaaatcaaca tctcttctta aaatacgcac acacatcgag
    18121 tgaaaagtcg atacccagac atcttcgcct ccagatgcga gaatcgcatt gacacgttct
    18181 ttcatttctt ttgcagcctt attggtaaaa gtaatcgcta ggatgttcca aggattgact
    18241 tctttttcct caatcaaata ggcaatgcgg tgtgtcagca ctctcgtctt tccacttcct
    18301 gcacctgcca ttagcagtaa tggtccgtca gtgtgaagaa cagcttcttt ctgacggggg
    18361 ttcatcccgt ttaataattc agctttggat gacattaaca acatcctttc ttttatcaat
    18421 cttgttaatt atagcatttt cttggctttc attaaactag ctagttcaaa atcatttgtt
    18481 tctttttatg gatttttcct tgtcaattcg ttgatttcgc gctaaattaa aagaaagcga
    18541 ggcgtttgaa tggaaaaaaa aggaaaaatc aagaaattag ataagactca gatatatttt
    18601 attctaaaag gaatatttgt tggactgctg acaggaatcg tcgttagcct gtttcgatta
    18661 tctatcgaaa agctaagcga tttagttcga agtatctatg aaatgagtcg ggaacagccg
    18721 atttacttaa ttggcctagc tatttgctgc atccttgcag catttttcgt gggttatctg
    18781 gtcaaaaatg aaccggatat caagggaagc gggattccac aagtagaggg acagcttcgc
    18841 ggggaattat caatgaactg gttctctgtt ttatggaaaa agttcattgg cggtgtactt
    18901 tcagttggtg cgggcctttt tctaggtaga gaaggacctt ctatacagct tggcgcatcc
    18961 attggacaag gagctggaca attgtttcgg agtccatctt cagaagaaaa gattttaatt
    19021 tctagcggtg caagtagcgg acttgcagca gcattcaatg ctcctatcgc aggattactc
    19081 tttgttttag aagaaatcca tcactccttt tctccacttg tttggctgac atcatttgct
    19141 tcagcaatca ctgctaactt cgtctctctt tactttttcg gcttgagacc tgttttatat
    19201 ctaggtgacc ttccttcttt gccgttgaaa tattatggtt ccttagtgat cttaggagta
    19261 cttctaggca tcttaggttt tatttatcag aatgtcttgc tggctttgcc aaaattttac
    19321 aaccgattgc ctttaccagc ttattttcac gggttcgttc ctttcttgct gattttgcca
    19381 attggttatt tatggcctag tactctaggc ggaggcaatc aaatcgtttt agcttttgga
    19441 catgcttcct tgccaatcat tatgattatc ggtttgtttg ttcttcgatt cgttttttcc
    19501 atgatttctt acggtggggg tcttccaggg gggattttcc ttccgatatt gacattgggg
    19561 gctttaatcg gtagctttta tggaaacatt atggttgatt tcgggatgga tccaatctac
    19621 atcaaggatt ttgtcgttat tgccatggct ggttatttca cagcgattgg aaaagcaccg
    19681 ctgacagcaa ttattttagt gacagaaatg gttggctctc ttaatcatct gatgccttta
    19741 ggattggctg ctcttgttgc ttatatcgtc aatgaccttc tcggcggtaa tccaatttac
    19801 gaatcattat tggaacgtct acttggaaat actcagaccg cctcactaaa aggtgcaagg
    19861 acaacttttg attttccagt aacggcagag agttctttag acggattaat ggtacgagac
    19921 ttcaattggc ctaaaaatat gctgctaatc tctatacgca gaggaaatca ggaaatcttg
    19981 actcacggtg atacgatcat gaatgtagga gatattttgg ttatcttgac tgatgaagca
    20041 aacttgccaa gaatcaagca ggaaatcgag gctaaatctt ctatcacaaa tttgaagcaa
    20101 tcattttaac gaacatggaa aaactatttt acaacaacta ttcatctaca ctacttgatt
    20161 ctatatgatt ctataaaaaa agaagaggct gggaaaaccc agcctcttct tttttatttc
    20221 tatgcttctg ctactgcagg agcttttctc aataaaccat aaatcacacc agatacgact
    20281 gctccgatag caataaacac caaatacatg accgggtgac tcagtaagaa tacaacgaaa
    20341 atcccgccgt gaggagccag taatttgatt ccgaaagctc cgactaatcc gccagttaaa
    20401 gcagaaccaa taataaaact tggaatggca cgaatcgggt cagctgctgc aaatggaatc
    20461 gatccttccg tgacaaacga tagtcccatc acgatgttcg tcaaaccagc atcttgatct
    20521 gttttgctga atttattctt aaacaaacgt gtagcaacga aaattgccaa tggaggtacc
    20581 attcctccag ccataacaga agccatcacg acacttccgc cagttgcaac agtcgtagct
    20641 aaagttgctg taccaaacac ataagcggct ttgttgattg gaccgcctaa atctgccgcc
    20701 atcattccag ctaataatgc accaagtaaa gcagcattcg aaccactcat acttgtcaag
    20761 aaaccgttca atgcatcatt gattgctttc atagggacat tgaccagcaa catcaagaaa
    20821 ccagtaatca gtaagccaaa cactggataa aagaggatcg ttttaattcc atccaatgat
    20881 tttggtaagt tcttgaataa tttacgtaaa aatacgatga cataaccagc taagaatcca
    20941 ccaatcagtg cacctaagaa tcctgcaccg cctgtattag ctaatgcacc agcagcaaat
    21001 ccaacgatca aaccagggcg gtcaccgata cttgaagcaa taaatcctgc taataccggc
    21061 agcatgaaac caaatgcagc ttgtccgatt tggttgaacc agctagcagc ttgattgtaa
    21121 ttccctagat ttgataattg atcatgtggc acgccaataa attggtcgat catgaaagaa
    21181 agcgcaatag cgattcctcc accaataacg aaaggtaaca tgtgtgatac gccgttcatc
    21241 aaatctttgt aaattctttg tccgatagta ccatccgcat ttccttcttc tgaactgctt
    21301 tcttttccat caccatggaa tactggtgca gtaccactaa gggctagatt gatcaactct
    21361 tctggtttac ggataccatc actgacagga cgattgatca gttcttttcc gtcaaagcga
    21421 ttcatctcta cttttttgtc tgctgcaacg attacacctt ctgcacgggc gatgtcttca
    21481 gcagtcaatc ggtttttgat tccttctgaa ccgttcgttt cgactttgat ctccacaccc
    21541 atttctttcg cttttttctt caaagcatct tctgccatgt aagtgtgagc gatccctgtt
    21601 ggacaagctg taacggcaac aacgaatttt ctttctggat gagcagaagc ttctgcagct
    21661 tgtgtttctt gttctgcttt ttcttctgct tctttttgct cttcagctgt ttggaacaag
    21721 tcttggactt cttctggtgt atttgcttct tttaattttc ctacgaaatc tgcatcaatc
    21781 agcaatcgag atagtgctgc taatgcttgc aaatgtgtgt cgtttgcgcc ttctggagct
    21841 gcgatcatga aaaacagata agttggctgt ccgtctaagg cttcataatc tactcctttt
    21901 tggctttttg cgaataaaac tgttgcttct ttaactgcac tgtttttcgc gtgaggcatg
    21961 gcgattccat caccaagacc tgtagaagtt tgtgcttcgc gggctagaat tccttcttta
    22021 tatgtttcga tatcggaaat ccggccggca tcaaacattt tttggaccat ttcatcgatt
    22081 gcgccttttt tatcagtcgc ttgcaaatcc atgatcatcg cttctttgac cattaaatcc
    22141 ttgatattca tgattatcct ccttgaaact aatcaatttt tgtgatttca acttctggca
    22201 gcaactcatc aatcaattcg cgagctgcca agtcatcaga aaaagctgtt gcgcttccgc
    22261 aagcaactcc ccatttaaag gcttcgattg gatctttcgt acggctgtaa gccccaataa
    22321 agccagcaat cattgaatcc cctgcaccta ctgaattttt caatgggcga actaatacat
    22381 tcgttttata agttccttgt tccgtgaaga gcaaagcacc gtctccagcc attgagatca
    22441 gcacattctg tgccccttca gctagtaatt ttttcccata cggaatgatt tcttctacag
    22501 attggaaggt tgtgttgtaa agctcagcta attcgtgatt gtttggtttg atcaacaacg
    22561 gtttcttaac aagtgcattt tttaggtcat cacctgttgt atcaatcacg aaatctgcac
    22621 ctttttctcg aatgatatca atcagttctt gataaaatcc ttttcgcagg ctagctggcg
    22681 cgcttcctga caatacgacg atatctcctt gtcctactgt tcctaatgct tgcttcaact
    22741 catcgatttc ttcatctgaa atagatgggc ctaagccatt gatctcagtt tcagtgtctg
    22801 attttagttt gatattgatt cttgtatctt cttttacggt tgtgaacaaa gactggattt
    22861 gttctttttc aagccacttc gaaataaatt cgccagtgaa ccctcctaaa aaccctagtg
    22921 ctgtagattg agaatcgatc cgtttcaaaa tacgggaaac attgatccct tttcctccag
    22981 gtaacttgaa gtcttccttc attcggttca aatcgcctag ttttaaccca tctacgcgta
    23041 cgatataatc aattgatgga ttaagtgtta ctgtgtaaat cattgtattg cctccttaat
    23101 tgttgtcttt tcacggaatt cattaacgaa ttctaatgga caacgctcgg ttatgatcgt
    23161 ggctgcttcc aaaggtgcaa cagaggtgaa ggacaactgg ttgaatttgg tatgatcaat
    23221 caatacaaat gtctcttcgg aatttttcat ggctaaacgt ttaacagctg cctcttctgg
    23281 atccggagtc gtgaatcctt gttcaagatg ggcaccgttc attcccataa atgctttatt
    23341 aaaatgaaaa ttttttagtt gttctatcgc attagatcct aaaacagcat tagttgccag
    23401 ctttatcgtt ccacctaaaa taatggtagc aagctccaaa tcaactaaat ttgccgcatg
    23461 ttgaacggaa tttgtcacta ctgtgatctg ttttccttgc agaaaaggaa tcatttctaa
    23521 cgtagtagag ccagcgtcta aataaatgac atcttcgtca ttaatggttt cagctgccga
    23581 tttggcgatt tgctgttttt cgtgaacgtt tttgagtgat ttttcactca tattctgctc
    23641 aaaattcaat aattgctctt tcttagctcc gccatgaact ctttctagaa acccactatt
    23701 ctccagctct tgtaaatcac gtcttatcgt tgattcagaa gcattcaaaa ggtttacaag
    23761 atcttgtgat ttcacgattt tctgctgttc aagcaagtct aggatttttt gtctgcgttc
    23821 ctctgtaagc attttcacga tcacctcaat acaaataata gcatattttt tttctactag
    23881 caatataaat cagtcaaaaa cgttcataaa aattataaat cagtcaaaaa aaaataaaaa
    23941 accagtcaga aagactggtt ttttattttt ttgtctatca tcaagccgtt ttatcgtttt
    24001 ttattttcgc ttcttgtttt tttcatataa acagaagcag gttttctttc cttatgaaga
    24061 agataataat aaagtcccat cccgccaaac atgaccaaaa aaccgatgac tgatcgaata
    24121 ggaaaattag gaacaaaaaa gagacagacg gataataatg atgccggaac cattattcga
    24181 taatagagtt gtttatccat tttcttcacc tcatattttt tgtaaagtaa tcaattgttc
    24241 taattctcgg taatctaaaa attgcacacg cagatgctgc tcacctttct tgacatcgaa
    24301 ttggatactt cgccgctttt tctttattcg tttgaaggta acatcagaga gtctatgttt
    24361 gatttccttt aacggtaatt ctgacaggga ttctgaagga acatagattc ttaaggataa
    24421 aagatactct tgatattttt catctgttac ctctacttct agatattccc taatataata
    24481 acaataagct tcgattccat tatccaaagc aacagtcgga tcgataactt tatagcacat
    24541 catgcgtgat cgattctcgt caacccaagg aaaatacgcc tgagcattta gtgttccgcg
    24601 aacacgcctt tctttataat ctccttgttg gatatcataa ctttttgtta caaaaaatga
    24661 agcattcttt ttaggaacag gttgcatttg tgcattctga tactggacag attggatcgt
    24721 atggtcagtg taaatgtatt caacgaatgg cggtttcaat aaaccgacac cattgtccca
    24781 agcaagatga tcaaacccaa gctggtccct aaaataggat tgaaacattt gattgtttgg
    24841 cttttgccag ttaaaggggt ctcgataaag ctggatacat atgacttcgt tttctaattc
    24901 cttcactttt tctacttgtt ggatgtcgag aaaaatcggt ttagggatga tttgatgata
    24961 atagcgacta taatacattt cccaacacga agtgaaacat aaaccttggt aaaaaagatc
    25021 gtatcctgga aattggttgc aatcgactac tacttccccg ttttgttgtt tcattttagg
    25081 taaatgttcg atttcatcct ttttctcaaa caatagccgt tgagagatct gttttgtatt
    25141 gtgatagata aactcgctat aagctcgcat ataggcgaac accccatgag caatcatttt
    25201 tttctgaatg aagtctcgaa tcaaaaattg cttttctttg aaaacagaga tagacaatac
    25261 attttttatc aataattgat tatcttccaa gcgaaaacta cattcgttct cgtcatttcc
    25321 tacaactaac caactttcgt ctcttaccga tgctagcatt attttttctt gaagctttcg
    25381 aagatcatac ggatccgctt gttgtgtgaa agagcggata aatgttggct ggatcaacag
    25441 acgtgtcaaa atagcccaat cgcttatttc ctgttttttt tcttcttcat ttaagtctgt
    25501 gagctggata gtcatcaata atttatcttc gccaatcatt ttctcacctc tttcaaatct
    25561 ttttataatt taattataac caatgataaa gaaaaactaa aactttatgt cttagaaacc
    25621 aatttggacg attacatgat agactaagta aaaagaaaca aagaggtgtt tacaatgggg
    25681 ttgaaatttg aacgtacaga taatttagat aaacttttcg aatcatttgc tgtcgatccg
    25741 gaaaaaacag ttgcaccaaa agaag
//
LOCUS       DAFTHM010000029        25564 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFTHM010000029 DAFTHM010000000
VERSION     DAFTHM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.029"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..438
                     /locus_tag="L7C88_001233"
     CDS             <1..438
                     /locus_tag="L7C88_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBP9558076.1"
                     /translation="ELYHHRAIYTNEDALVIKKEQGFTGTETKSLFLKDKKDNNYVYL
                     TFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFGYEKQIPIIIDEELLS
                     NEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN"
     gene            475..1485
                     /locus_tag="L7C88_001234"
     CDS             475..1485
                     /locus_tag="L7C88_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBP9558077.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(1600..2313)
                     /locus_tag="L7C88_001235"
     CDS             complement(1600..2313)
                     /locus_tag="L7C88_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558078.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(2503..3093)
                     /locus_tag="L7C88_001236"
     CDS             complement(2503..3093)
                     /locus_tag="L7C88_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBP9558079.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            3577..3804
                     /locus_tag="L7C88_001237"
     CDS             3577..3804
                     /locus_tag="L7C88_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBP9558080.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            3820..4986
                     /locus_tag="L7C88_001238"
     CDS             3820..4986
                     /locus_tag="L7C88_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBP9558081.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            5220..6263
                     /gene="hrcA"
                     /locus_tag="L7C88_001239"
     CDS             5220..6263
                     /gene="hrcA"
                     /locus_tag="L7C88_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBP9558082.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            6357..6920
                     /gene="grpE"
                     /locus_tag="L7C88_001240"
     CDS             6357..6920
                     /gene="grpE"
                     /locus_tag="L7C88_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBP9558083.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            6971..8800
                     /gene="dnaK"
                     /locus_tag="L7C88_001241"
     CDS             6971..8800
                     /gene="dnaK"
                     /locus_tag="L7C88_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBP9558084.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            8951..10117
                     /gene="dnaJ"
                     /locus_tag="L7C88_001242"
     CDS             8951..10117
                     /gene="dnaJ"
                     /locus_tag="L7C88_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBP9558085.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(10199..10864)
                     /locus_tag="L7C88_001243"
     CDS             complement(10199..10864)
                     /locus_tag="L7C88_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558086.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            10840..11013
                     /locus_tag="L7C88_001244"
     CDS             10840..11013
                     /locus_tag="L7C88_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558087.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(11058..11795)
                     /locus_tag="L7C88_001245"
     CDS             complement(11058..11795)
                     /locus_tag="L7C88_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBP9558088.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(11797..13299)
                     /locus_tag="L7C88_001246"
     CDS             complement(11797..13299)
                     /locus_tag="L7C88_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBP9558089.1"
                     /translation="MKRKHLFHSFVFLMTGLVTFAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13558..15552
                     /gene="uvrB"
                     /locus_tag="L7C88_001247"
     CDS             13558..15552
                     /gene="uvrB"
                     /locus_tag="L7C88_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBP9558090.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            15562..18378
                     /gene="uvrA"
                     /locus_tag="L7C88_001248"
     CDS             15562..18378
                     /gene="uvrA"
                     /locus_tag="L7C88_001248"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBP9558091.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            18641..19906
                     /locus_tag="L7C88_001249"
     CDS             18641..19906
                     /locus_tag="L7C88_001249"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBP9558092.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            19910..20641
                     /locus_tag="L7C88_001250"
     CDS             19910..20641
                     /locus_tag="L7C88_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBP9558093.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            20776..21660
                     /gene="rapZ"
                     /locus_tag="L7C88_001251"
     CDS             20776..21660
                     /gene="rapZ"
                     /locus_tag="L7C88_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBP9558094.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            21657..22655
                     /locus_tag="L7C88_001252"
     CDS             21657..22655
                     /locus_tag="L7C88_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBP9558095.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            22689..23624
                     /gene="whiA"
                     /locus_tag="L7C88_001253"
     CDS             22689..23624
                     /gene="whiA"
                     /locus_tag="L7C88_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBP9558096.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            24167..24817
                     /locus_tag="L7C88_001254"
     CDS             24167..24817
                     /locus_tag="L7C88_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558097.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            25004..>25564
                     /locus_tag="L7C88_001255"
     CDS             25004..>25564
                     /locus_tag="L7C88_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBP9558098.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         8430 a         4333 c         5471 g         7330 t
ORIGIN      
        1 gagttgtatc atcatcgagc catttataca aatgaagatg ctttggtaat aaagaaagaa
       61 caaggattta caggtacaga gaccaaaagc ttattcttaa aagataaaaa agataataac
      121 tacgtatatc tgacttttac tacgaaacaa acggatttca aagcattagg gaagatcgtc
      181 ggtaaaaggc tttctattgt ttcatcagaa cgcatggaag aacaaacggg acaaaagcag
      241 ggcgctgttt ctccgtttgg ttatgaaaaa cagattccga ttattattga tgaagagctc
      301 ttatcaaatg aaaaacttgt ttttgcacca ggtagaccag atcaaacgat ggtcatccaa
      361 acggttgact taaacaaaat catccagcta cttgagatgc cgatattttt gatgccggca
      421 aacgaaaaaa acaattaacc aagtaaaata gtgcatactt ggaggtgaag caacatgata
      481 agttatccat tattagaaag aaatgcaacg attggggtta ctgcaccatc ctcaggcgta
      541 tcagaggaac accattcgtt actcgaatca gctttaaaga gaatggaaga aaaatctttc
      601 caagtagtta ctggaaagac gctttggacg caagataagg aaaaatcagg tccagcaaga
      661 aaacgagcag atgaattcaa tcaaatgatg caagatgaaa atatccaaat gatctttccg
      721 acttggggag gagaattatt gattgagatt ctcgattttg tcgattttga tgctctacaa
      781 ccaaaatgga tagtaggtta ttcagatatt agtacgttgc tacttgctgt cacattaaaa
      841 acagggatag ccactgcaca tggaactaac cttattgatt taagaggaga gtacttggat
      901 gaaacgacag caatgtggga aagtgtactg aaaacaagag aaggagaatc gattctacag
      961 caatcttctg aaaagtatca aaaagtgtgg ccccatgagc attcatcatc ttctgttttc
     1021 catctcactg aaccaacaaa ttggcaatca gtcagcggag atgcagtaag gatgaaggga
     1081 cgattattag gtggttgtat tgatacgatc aggcatttaa tcggtactcc ttatggagat
     1141 gtccaatctt ttaaaagaaa gtataatgat ggaaagccga tcttgtggtt tctagaaaac
     1201 tgtgagctat cgtcagttga tttaagaaga tcacttgttc agatgaaact ggcaggctgg
     1261 tttgatggca gctcggggat catgttcggt agaagtgcgg cagaggattt gttagattat
     1321 aaaatgaagg atgtatacga agatctgtca aaggaattaa aactaccgat cttgtatgat
     1381 attgattgtg gtcatgtacc gccacaactg acattgatta atggtgccta tgcagaagta
     1441 gcggtagaag atagaaaagc gactgttttg caaacgttta tttaaaaaat tttttcctgc
     1501 cttggagtct atcaaagacc aataaatcta aatagaaaag aaagtgaaag aagctgacaa
     1561 aatgctgtca gcttcttttt gtataacata ttagaaagtc taattatcta taactgtcac
     1621 atcgattaac tgtttcacgt cattgggatt tcctgtagga atagctacta cagatgcatt
     1681 atcaatgatt tcttgagttg tttctctaat gaacgctgga taagatgttt gatctgcagg
     1741 catttgccaa tgtgaaggaa ctggataact agtgattgtc ccgtcatggt tacttgaata
     1801 cactaaaact ccctggtaac tgtatttccc agtgagcata accacatctt tcggatagac
     1861 tgcactccct gcatcataag gggcgatagg tgttcctgca ggataatgaa taacatgtaa
     1921 ttcgaaatca cccgatgtat ctctaaaagt attacctcta atagctagcc aaacacgtgc
     1981 gtactcaatt tgtagatcag aatatcctgc taacggatct attgactgag aagactgtga
     2041 ggaggttgtg tctattgttg aagaagaaat atttgtctca actgtactac tagatgtaga
     2101 agaagtattg ggctctgaga ctttactgct tgttgaagat gtattcgttt cagtagaagc
     2161 tgatttctga gtacttgatt tttcagctga actggtttgt ctgattgaac ttttgtctgt
     2221 ggtcgcagat ggatcactat tttctttact aggagacgta catcctacaa ggaataaaga
     2281 gaccaacaat aaaataaaac ctaacttttt catataaaat acctcattat ttttttaata
     2341 ccagtatagc ataatcctga atttttgaat ccgtaaaacc ttgtctatga atataaatag
     2401 agtgtatctt ctttgataaa tgtcagaaaa agtgtgacaa ataatcatca gtaaaattac
     2461 ttgtcacact attgataagg agtatttaat tgaagagaat gattaggaga aaggatctcc
     2521 gtacttttta tagtaatcat agaatccaag tttgtataga cgaatcgttt tttctcttat
     2581 ttcttctgtt tcaaaatgga ctgcttgaag aatcaagtct gtgaattcta taggagctgt
     2641 tccattcgca gtaatcaaat tacgatcttt cacagcttgt tgttctataa aatcttcttt
     2701 attctgataa ttttccgatt ctaaccaagg aaattgcgca tttccggtgt gtttgtaacc
     2761 ttgcaataat ccgctctgag ctaaataatc aactgcccca caaatagcag ctactggtac
     2821 gtctgttttt aacaatttat cgattatttg atataaatga tgatttttta tgtcccatga
     2881 attgccaccg atcataataa aaaggtcaac tttttcaggt atttgttcga ttaagtaatc
     2941 gatttttgtt tttaatcctc caatggaagt gacctctgat tggatagaag cagttttgtt
     3001 ttgccatttc tcattttggt ttagtgtgct agtaatataa gcaccttccc aatcggcata
     3061 ttcctctaat agaaacgtaa tcgcagtttt cattttcaag ctctccttta ctatctataa
     3121 caaggacaac agttttaacc tacagacatt cattaaaatt gggtagcgac agcgaaaaca
     3181 acaattctta agttttagac agagtataca gatagtcaac ttaattaaat acgaactaaa
     3241 taaaaatgac aggtaatcat ttttgtttac cagcattata acattttgca tacatggatg
     3301 acaaaagaac caattcccac ttgcttgagt acaatattaa aagaaactgg aaggcaaaaa
     3361 gtaattatag aaacgaaaaa taaatcatat cgggcactca gacatgaaaa caaccctaga
     3421 gatatataac taggtaacca gtttaatgaa agaaaaaatc atccaagaag tcgattcttg
     3481 gattttttag tggatttgtt cgccaaatac gtttagtatg cgtatatgag aggttgtaag
     3541 caaagcgttg tggtctgagc acttaaggag gaatctgtga aaatagcttt tcatattttt
     3601 gcagattttg acttaatgcc gaaggtcagc tttgcgatta ccgtttatcg agaggctgta
     3661 aaagcaccgt gtagctccga tgacaataag caagcatttt tagagctagg tttccttgat
     3721 tctaaatatg cggcttattt caatgagttg gtgcttgaac gcgattttaa gaaggtcgaa
     3781 aacaggcacg acttttcgac gtaaggagaa agaatttcaa tgatagaaac aataaatccc
     3841 gcagaaaaca aggtttctgc gtacattcat atcccatttt gcgagcatat ctgctattac
     3901 tgtgatttta ataaagtttt tttagaaggg cagccagtag atgagtatgt ggaaatgctg
     3961 ctgaatgaaa tgaaaataat gctagaaagt catccgacag cgaatttaga aacactttac
     4021 gtagggggcg ggacaccaac ttctttatct gctaaacaac ttgatcgact gttatcaggt
     4081 gctagagaga tcctgccttt tcaaaatggt aatgagttta ctgtagaagc gaatccaggt
     4141 gatttgaccc gtgaaaaact tcaagtaatg aaaaactatg gcgtcaatcg tttatccatg
     4201 ggagtgcaga catttgataa tcgcttattg aaaaaaattg gacgtaaaca caccgcagaa
     4261 gatgtgtatc aaactatgca atttttagaa gcagaaaatt ttaccaatgt aagcatcgat
     4321 ttgatttatg cattaccggg acaaacacta gaaggatatc tggatacttt ggaaaaagct
     4381 ttggctttgg atctgcctca ctattctttg tactcattga tcctcgaaaa caaaacaatg
     4441 ttcatgaact gggtacgaca aggaagactc gaactgcctg atcaggaaac ggaaaccaga
     4501 atgtttgaag agacgattga agcaatggaa aagcatggac gtcaccaata tgaaataagt
     4561 aactttgggc tctccggaca tgaatctcaa cataacctca tgtactggaa caatgaccac
     4621 tattttgggt ttggagctgg tgctagcggt tatcttggag atattcgtta ccgcaacaaa
     4681 ggaccaatcc aacactattt acgcccatta cgagcaaatg aacgcccggt attggaagaa
     4741 gaaaaattga cacgaaaaaa tcaaatagaa gaagaaatgt tcttaggact aagaaaaaaa
     4801 acagggatta ctaaaaaaca tttctatgat cgctatcaaa aaacaattga atcggtgtac
     4861 ggtgatgtgc taagggaatt agagcaagaa gggttacttg ttaatgaaga agaccgtgtt
     4921 tatttgacac caagagggac ctttttgggg aacaatgtgt ttgagcgctt tttgtttgaa
     4981 aaatagttta aagaatattt gttttttatc tgaatttaaa taaaaaaagt tcaaaaatac
     5041 aataaaggac tattgaaacg ttgatataac tggatttaca tcaattattt agaattagca
     5101 ctcttgtgtt tagagtgcta aaaaatggag tctttctctt gacaggagaa gggcttcttg
     5161 ctatatttat aagtggatta gcacttagaa tatatgagtg ctaatgagag gtgaggaaga
     5221 tgttaacaaa gcgacaaaac gacattttac gtctgatcat ccaacactat acgagtagtg
     5281 gcgtgcccgt tggttccaaa acattgatgt ctgagggagt caaggccagc tcagcaacga
     5341 ttcgcaatga tatgaaagca ttagaagatg aaggattgct gttgaagact cactcttctt
     5401 ctgggcggat tccatctgct ttaggctatc gttattacgt ggatcatttg ttaaaacctg
     5461 ctcgcgtagc agaagatgat ttgctgctga ttcgtcagtc tctaggcaga gaatttcatg
     5521 aaatcaatga gattattaag caatctgctg agatattatc tgagctgaca agctatacga
     5581 ctttttcatt gggacctgaa ataaaagacc gccgactgac tggctttcgt atcgtaccct
     5641 tgaataatcg acagattatt gctatcgtcg taacagatat ggggaatgta gaaagccaag
     5701 tgttcactct tcccgaatat atgggaagtc aggaactaga aaaaatggta cagattgtaa
     5761 acgaccgtct agtcggagat cctctgatga cggtgtacca taaacttcgt acggagattc
     5821 cgatgattct tcataaatat ttccaaacga cagaagggat gtctcagtta tttgacaccg
     5881 ttcttggtca tgtttttgaa gataaggttt atgtcagtgg acaaatgaat ctcttggatt
     5941 atgagccccg tcaagatctt gatcagttca aatcgatgtt ttcttttatg aaagactcag
     6001 acggacttac acaaatgatc actccgatgg atagcaatat tcatatcaag attggtgctg
     6061 aattaggcaa tgatttattg cagaatatga gtatgattca agcaagttac gagatagatg
     6121 gtcatggaag aggtacaata gccttgttag ggcctactag tatgccttat tctcggatgt
     6181 tcggtctagt cgatgtttat cgaagagaac tagcagctaa acttgctgat tactaccgtt
     6241 cgcttgactt gtcaaactcg taatgtgaat aacgaagcta tttgcagctg atcgttctct
     6301 ctttcttagt aagagcaatc aaacagctga ctgaataatg aaaggaagac tgtatcgtga
     6361 aagaaaatca agaagaacta gataaagaaa tgacagatgc tcagccagaa ccggaaatcg
     6421 atgtcgaagc tgcagaagat tcgggtattt cagaagctga agcggaagaa ttcgaaacag
     6481 cgaaattaaa agctgagtta gaagaaatgg aagataaata cttgcgggct cgtgctgaaa
     6541 tcgcaaatat ggcaaatcga ggaaaaaatg agcgtgagca attacaaaaa taccgttcac
     6601 aagatttagc caaaaaatta cttccatcaa ttgacaacct ggaacgtgca ttagccacag
     6661 aagtgtcaga tgatcaaggg gcaggtttga aaaaaggcgt ggaaatggtc ttggaaagtt
     6721 tgcgtaacgc actggaagaa gaaggaattg aaaaaatccc tgctaaagga gaagcctttg
     6781 atcctaatct tcatcaagca gtacaaactg ttccagcgac tgaagataca ccagccgata
     6841 cgattgtaga agtactacaa gaaggctaca aattacatga tcgcgtgtta agaccaacca
     6901 tggtcattgt tgcacaataa ttgtgcggat ataaaactta cactttcaat taaagaagga
     6961 gacgttaatt atgagtaaaa ttatcggtat tgacttaggt acgactaact ctgcagtagc
     7021 agtattggaa ggaaacgaag caaaaatcat cgctaaccca gaaggaaacc gtacaacacc
     7081 ttctgttgta tcattcaaaa atggagaaat ccaagtaggg gaagttgcaa aacgtcaagc
     7141 tgtgacaaac ccaaatacga tttcatcaat caaacgccat atcggtgaag caggttacaa
     7201 agtagatgta gaaggtaaat catatacacc acaagaaatc tcagcaatga tccttcaata
     7261 tatcaaagga ttcgcagaag actatttagg tgaaaaagtc gaaaaagcag ttatcactgt
     7321 gccagcttac tttaatgatg cacaacgtca agcaacaaaa gatgctggta agatcgctgg
     7381 tctagaagta gaacgtatcg tcaatgaacc aactgcagct gctcttgcct atggtttaga
     7441 taaaacagat cgcgacgaaa aaatcttagt attcgacctt ggtggcggta cttttgacgt
     7501 atctatcctt gaactaggag acggtgtctt tgatgtattg tcaacagctg gcgacaacca
     7561 tctaggtggg gacgactttg ataacaaaat catcgactac atggtagcag aattcaaaaa
     7621 agaaaacagc attgacttgt ctcaagacaa aatggcttta caacgcttga aagacgctgc
     7681 tgaaaaagcg aaaaaagatt tatctggcgt atcaagcaca caaatcagct tgccatttat
     7741 cacagcagga gaatctggac cattgcattt ggaaatgaca ttgacacgtg caaaatttga
     7801 tgaattaaca gctgacttag tagaacgtac aaaagtacca gtacgtcaag cgctaaaaga
     7861 tgcaggttta tcacaatcag aaatcgacga agttatttta gtcggtggat ctactcgtat
     7921 ccctgcagtt gtagaagcag tacgtaaaga aacaggaaaa gaaccaaaca aatcagttaa
     7981 ccctgatgaa gtagttgcta tgggtgctgc tatccaaggt ggcgtgatca ctggtgatgt
     8041 gaaagatgtt gttttacttg acgttacacc attgtcatta ggtatcgaaa caatgggtgg
     8101 agtgttcact aaattgattg accgcaatac aacgattcca acaagtaaat cacaagtatt
     8161 ctcaactgcg gcagataatc aaccagcagt agacatccat gtattacaag gtgaacgccc
     8221 aatggctgct gacaacaaaa ctctaggaag attccaattg acagatattc cagcagctcc
     8281 tcgtggtatt ccacaaatcg aagtaacatt cgatattgat aaaaacggga ttgtaaatgt
     8341 atctgcgaaa gatctaggta cacaaaaaga acaaaaaatc acgatcaaat cttcttcagg
     8401 tctaacagac gaagaaatcg aacgtatggt aaaagatgca gaagcaaatg cagaagcaga
     8461 taaagctcgt aaagaggaag ttgacctacg taatgatgta gatgcattgc tattctctgt
     8521 ggacaaaaca ttgaaagaat tagaaggcaa agtggacgaa gaagaagtga aaaaagcaga
     8581 aacagctcgc gatgaattga aagccgctgt tgaagcaaac aacatcgaag aaatgaaaac
     8641 taaacgcgat gcattgaacg aaatcgttca aaacttgact gttaaactat acgaacaagc
     8701 ggcacaacaa caagctcaag aaaacccaga agcagctcaa ggcggagcag atgatgtcgt
     8761 tgatgctgat tttgaagaag tcgatggcga cgataaataa tcagttcact gaatttcgag
     8821 agaaggccaa agttgctact ttggcttttt cttttgaaaa atagtttgaa gtatcggttt
     8881 ttgtttcaaa caaaatatga tatgataaca agcgacgtga aaatgatgag aaccaatagg
     8941 aggaaagcct atggcaacaa aacgtgatta ttatgaagtc ttagggctct caaaaggagc
     9001 atcagaagat gaaataaaga aagcttatcg taagctttcg aaaaaatacc atcctgacat
     9061 caataaagaa cctgatgcgg aagaaaaatt caaagaagta tcagaagcat atgagatttt
     9121 aagtgacccg caaaaacgcg ctgcatatga ccaatacggg catgcaggca cagatccaaa
     9181 ttacggtgct ggtggagctg gtggcggatt tggtggattc ggcggcttct ctggtggcgg
     9241 cttcggtggt tttgaagata tcttcgactc tttctttgga ggaggcggtc ggtcagtcga
     9301 tccaaatgcg cctcgtcaag gtgctgattt gcaatatacg gtcgacttgt cttttgaaga
     9361 agcgattttt ggtgtagaaa aagaaatcaa gtataatcgg gaagaaatct gtcatacttg
     9421 tggtgggaac ggtgcaaaac caggcacaca accaactact tgtcataaat gtcatggtgc
     9481 aggtacgatt aatgtagaac gccaaacacc acttggacga gtgatgagcc gtcaaacttg
     9541 tgatgtttgt catgggacag ggaaagaaat caaagaacct tgtccaacct gtcatggctc
     9601 aggacatgag aagaaagcac attcagttaa agtgaatgta ccagctggtg tagaagaagg
     9661 acaacaaatg cgtttagctg gtcaaggaga agctggagaa aacggcggac catttggtga
     9721 tttgtatgtg gtcttccgtg tagaagaaag tgatatcttt gatcgtgaag gttctgaaat
     9781 ttactatgaa ttgcctttaa gttttgtaca agcagctttg ggggatgaag tccaagtacc
     9841 aactgtccat ggagatgtga aattgaagat ccctgctgga acacagacag gtacgaactt
     9901 ccgtttacgt ggaaaaggcg ctccgaagtt acgtggtggt gcaacaggcg accaacatgt
     9961 caaagtaaaa ctgatcacac cgaaaaatct aaatgaacaa caaagagaag cattacgtgc
    10021 attcgctgaa gctggcggca tcaaagttga agaacagcaa gaagacggtt tcttcgataa
    10081 gtttaaagat gcttttggcg ggaaaaagcg gaagtagttt ttctagtaaa aacgctaagt
    10141 cattaataat taaaaaccag acgaacaatc atatgttcgc ctggtttttt tgtagttgtc
    10201 atgtttgtac caacaaaaaa gccagcttta gaatatgata atcgtcatag tttctagggg
    10261 tataaccagt gagagaatgg aacttgttca atcgatattg caaggtgttt ttatgaataa
    10321 ataattcttc tgagcaattt ttgatgcttc cgttattttt actgaagcat gccaaagtct
    10381 tcttgaacaa atgtacttct tcttctgtca ggcttttcaa aatacgtttt acatataatg
    10441 ttcgttgatc tgacgggatt gctggtaaaa cgatcccgag gtctaaatct tcaaaaaagc
    10501 ggatctcgtt cacagattga tggaaagcta tccattcgca aacttgtttg gcatgaagga
    10561 aagattgcgg tgtctcttgc tctgtataac aaagcgaccc aattccaaag tttagctgta
    10621 actgatacat tttattaaac tttgtctgga ttttatcaag caatgatagc aatgaggctc
    10681 tggaaatccg attgactagg ataatgattt gttgtctatg tacagtgagc aaagcctgtc
    10741 cgtaataaga gaagaccctt tcgagcaact ccaataaagg attgatccgt tcttgacaca
    10801 attgctgatt gtcagaaagt tgtcccacaa ctacataata tggagaagaa aaatcaagct
    10861 caattaagtg agggtggtat cgactatgta cttgatatca tcaatgaacc gatggtactt
    10921 tcttatgcga tggaacaggt agagcgattg cttgtttgtg caggaaaaca agcgatgcgg
    10981 ctgatacgat taggtgagaa aataagaaga taaaaataca cggtcccttc atggcgaccg
    11041 tgcatttttg gtttttatta aatatttaat actttattca agaaatcttt tgtccgttca
    11101 ttttgcggat tttcaaagat ttgttgaggc gttccatctt ctaaaaagtt tccgtcgtca
    11161 atgaacatga cgcgattggc cacttcttta gcgaacccca tttcgtgcgt aacgataacc
    11221 atcgtcatac cttgttctgc taactttttc atgacgttca agacatcacc gaccatttca
    11281 ggatcgagtg cagaagtagg ctcatcaaaa agcatgatgt cagggttcat cgctagagca
    11341 cgagcaatag ccacacgctg tttttgtcca ccagaaagca tttcaggata catatctttt
    11401 ttatcttcta gaccaactgt ctgcagtaat ttgattgctt ttttctctgc ttcttctcta
    11461 gattctttct tcaggtccat cggtgctaaa atgatgtttt ccaaaataga aagatgaggg
    11521 aataggttaa agtgttggaa taccattccg atatgttgtc tcaccaagtt gatatctgtg
    11581 cttttatcca tcaagtgggc gccgtcaata ataatttcac cgtcagaagg ttcttctaaa
    11641 cgattcaagc aacgcaagaa tgtacttttt cctgaacctg aagggccaat gatacagacg
    11701 acatctcctt cgttgatgga tacattgatg tcgtttaata ctgtgttatc gccgtatttt
    11761 ttgactaaat gctcaactaa gattttttct gccatcttac ttcaccttct tttctaaaac
    11821 ttttgctaat tttgtcaatg ctgtgatcaa aatcaagtac atgatcgcaa tgatcaagta
    11881 aacatacgta ctttgtgttg tacgtgcaac aatgatctta ccagtttgca gcaattcgac
    11941 tacaccgatt gcggaaatga tcgttgtgtc ttttaatgag ataacgaact gattgacgaa
    12001 tgatgggatc atgatgcgta tcgcttgcgg caaaatgatt ttttgcattg tccgattata
    12061 agaaagacct aaacttctgg aagcttccat ttgtccgaca ggaacggcgt tgatcccgcc
    12121 tcgaacaatc tctgcgatat aagcacttgc gttaagagtc aaggtgataa caccagcaag
    12181 gaagtcagga atcgtaaatc caacgatacc aggcaaccca aagaaaataa agaacgcaag
    12241 aaccatcatt ggaattcctc ggatgatatc gacataaata ctagcaattg tgcgaagagc
    12301 gcgtattggt gctacactga ataatccaaa aatcacaccg attactatag ccaaagcaaa
    12361 ggagatcaaa gttaggagaa ttgttctcca aagtcctttc aacaatgctt gatagttgtt
    12421 ttggataagt ccaagaaatg ttgattcatc agcagtggaa gactcactgg aagtttctga
    12481 accatccgct acatattctt taataatctt atcgtattcg cctgttcttt ttaattcttt
    12541 caatccttca ttgaacatat taagaagctc aggattttgt ccttttttaa cggcaaatgc
    12601 atattttccg ccagattctt ttttgatcgg tgtttccaat tcttgtcctt gtttgatcgc
    12661 ataaccgatt accggataat catccatcat tgcatcgatt gcgccaactt ttaacccgtc
    12721 gtacaattga tcagcagcat caaaatattt gatagaatag ccatattcag attcatggtc
    12781 gcttaaaaat tcagcacttt cggtaccaac ttttgctccg actgtttttc ctttcaaatc
    12841 ttcataagac ttgatcgaag tatctccttt tttgacagct aattggatcc cgctatcaaa
    12901 gtaagaatca gaaaaatcat agcttttctt tcgttcatct gttacagtca ttccggcaat
    12961 cattccgtct gcttgtcctg attccaaagc ttgcaaagca gcagagaaac cacggtagtc
    13021 cattcggatg ttaaatcctt gcagtttggc gatgttttcc atcaatttta catcgatgcc
    13081 ttcgtactcg ccctttgcgt tttgaaattc aaatggagca aaagcagagt cactggcaat
    13141 tacgtatacg tcttttttgg gctctatttt ttgcattgtc tcgcttgtgc ttgactctgc
    13201 cgttgtagtg ttgtcagctt gtgcaacatg accaaacgca aatgtcacaa gtcctgtcat
    13261 taagaaaaca aatgagtgaa ataaatgctt tcttttcata atcaacctcc taaatttcca
    13321 atattttatt attataggcg aaaagtgctg aatcagacaa gactgtaagc tcgaaaaaat
    13381 gaaaaaaatg cgagtttcta acattttatg ttataaaaca taacatgtat aataagataa
    13441 aaaagtggcg aaagtatgtt cggtgtggta taatttttta gtaaggaatg cctttgcttt
    13501 ccttttcttt ttattggtcg taaaatgaaa aggaatgaat gaaaaggagg acgaagaatg
    13561 attgagagag atacctcccg acactttgag cttgtctcga aataccaacc ggctggtgat
    13621 cagcctgaag cgattaacca attagtggat ggcgtagtcg gcgggaaaaa agcacaaatc
    13681 ttattaggtg cgactggaac agggaaaaca tatacgattt ccaatcttat tgagaaagtg
    13741 aataaaccaa cactgattat tgcccataac aaaacattgg ctggtcagct gtacggggaa
    13801 ttcaaggaat ttttccctaa caatgctgtt gaatattttg tttcttatta tgattattat
    13861 cagcctgaag cttatgtgcc ttcaagcgat acgtatatcg aaaaagattc aagtgtaaat
    13921 gatgagatcg acaaattacg acattcggct actagttcat tattagaaag aaatgatgtg
    13981 atcgtcattg catccgtttc atgtattttt ggattaggct cgccttttga gtaccaaaaa
    14041 caagtagttt cgattcgaca gggagcagaa ctagatcgca atcagttgat tcgtgactta
    14101 gtcagtatcc aattcgaaag aaatgatata gattttcagc gcggtcgttt tcgagtgcgc
    14161 ggtgatgtcg tggagatttt tccggcttca agagatgaac gtgccttacg tgtggagttt
    14221 tttggagatg aggtcgaacg tatccgagaa gtcaatgcac tgacaggtga agttttagga
    14281 gaaacggaac acgtagcaat cttcccggcg actcactttg tgacgaatga tgaacatatg
    14341 gagcatgccg tagcgaatat caaagcggaa ttagaacagc gtttaactgt cttgcgaaat
    14401 gaaaacaaac ttctggaagc tcaacgttta gaacagcgaa ccaattacga tattgaaatg
    14461 atgttagaaa tgggctacac gtcgggaatt gaaaattatt ctcggcatat ggacggacgt
    14521 aaagaaggtg aaccgcctta tacgctattg gatttctttc ctgaagattt tttgatcgtg
    14581 gcggacgaat cgcacgtaac catgcctcaa atcagaggaa tgtataatgg tgaccgagcg
    14641 agaaaacaga tgctagtaga ttacggtttc cgtttgccat ctgctttaga caatcggcca
    14701 cttcggttag aagagtttga aaaacatgtc aatcagatca tttatgtctc tgcgacgcca
    14761 ggaccatatg aacatgaaca aacagatacc gttatccaac aaatcatccg tccgacaggg
    14821 ctgcttgacc cagtgatcga agttcgtcca atcatgggac aaatcgatga tctagtaggc
    14881 gaaataaatg aacgagtcga aaaagaccag cgggtgtttg taacgacatt gacgaaaaaa
    14941 atggcagaag acctcacaga ttatttcaaa gaattaggga tcaaagtcaa atatttgcat
    15001 agtgatatca aaacgctgga acgaacagaa atcattcgag atcttcgatt aggtgaattt
    15061 gatgtgttag ttggaatcaa tttgcttcgt gaaggattag acgtacctga agtttccctt
    15121 gttgctatct tggatgcgga taaagaaggc tttttacgta gtgaacgttc cttagtccaa
    15181 acgattggac gagctgctcg gaatgaagaa ggtaaagtaa tcatgtacgc agacaaagta
    15241 acagattcta tgcgtctagc gatggatgaa acgtcaagac gtcgtacgat tcagcagaag
    15301 tacaatgaag aacatgggat cgttccaaaa acgatcatta aagaaatccg agatttgatt
    15361 tctattacga aagaatcgga agatgataca aaagaagcgg tacaagtctc gtacgaagaa
    15421 atgacgaagg aagaaaaaga cacgttattg atgaaattag aaaaagaaat gaaagatgcg
    15481 gcaaaagctt tggattttga aacagccgcg aatgtgcgag atatgatttt agaattaaaa
    15541 gcttcaaagt aggaggacaa catggctaac gataaaatta cgattcatgg tgcacgtgcc
    15601 cataacttga aaaatataga tgtaacgatt ccacgagata aattcgtggt cgttacaggt
    15661 ttgtccggtt ctggaaaaag ttccctagca tttgatacgc tgtacgctga agggcagcgg
    15721 agatacgtag agagcctttc tgcttatgct cgtcagtttt taggacaaat ggataagccg
    15781 gacgtagata gcatcgacgg attgagtccg gcgatttcta ttgatcagaa aacaacaagt
    15841 aaaaatcctc ggtcgacagt aggtactgtg acggaaatca atgactattt acgcttgttg
    15901 tttgcacgtg taggacatcc gatttgtccc aacgatcata tcgagattac cagtcaatca
    15961 gtagatcaaa tggcagatca agtaatggct ttgcctgagc gcacaaagat ccaagtgttg
    16021 gcaccgatcg tggtaaagaa aaaaggacaa cataaaaaaa tattcgaacg aatccaaaaa
    16081 gagggatacg tccgcgttcg agtcgatggt gagatctatg atttaagtga agtgcctgag
    16141 ctggagaaaa acaaaaaaca tgatatcgcg atcgtcatcg accggatcat tgtgaaagaa
    16201 gggattcgtt ctcgcctatt tgattcttta gaggcggccc tgcgattagc agacggctat
    16261 gctctggttg acgtgatcgg tgaagaagaa atgttgttta gcgaacacta tgcctgtcct
    16321 tattgcggat ttactgttgg cgaactagaa ccaagactgt tctcattcaa tgcgcctttt
    16381 ggagcttgtc cagactgtga tggtttaggt gtcaaattag aagtcgatca agatttagtg
    16441 attccagata gaacgaagac acttagtcaa ggtgctatcg ttccatggaa tccaatcagc
    16501 tctcagtatt atcctcaaat gttagcgcag gcttgtgaaa gtttcggtat cgatttagat
    16561 acaccattcg aagaattacc ggaagagcat caggagatca tcttgaatgg gacagatgat
    16621 cttttccatt tccattatga aaatgatttt ggtggcgttc gcgatgtaga aacgactttc
    16681 gaaggggtat tgaagaatat cgagcgtcgt tatcatgata cgaacagtga tttcacgcgt
    16741 gagcaaatgc gtctttatat gacagaatta acttgtcaga catgtaaagg ttatcgattg
    16801 aatccccaag ctctatctgt tcaaatcaat ggaacgaata tcgggcaaac aaatgagttg
    16861 tctattcaaa aagcagtaga tttcttctca aacttaacgt tatctgaaca agagaaagta
    16921 attgccaaac cgattttaaa agaagtaaat gacagacttt cattcttgga aaatgtggga
    16981 ctagactatc taactttgag tcgcgcttcc ggaacattat ctgggggaga agcgcagcga
    17041 atcagattgg ctacacaaat tggatcgaat ctttctggag ttttgtatat tttagatgaa
    17101 ccatcgatcg gattgcatca acgcgacaac gatcgactga ttggctcatt aaagaaaatg
    17161 cgtgatcttg gcaacaccct cgttgtagtc gaacatgatg aagatacgat gtgggcagca
    17221 gattatttga ttgacgtcgg acctggggcc ggagaacaag gcggacaaat cgtggctgca
    17281 ggcactcctg aagaagtagc taatgatgaa aattctttga cagggaaata tctttcaggg
    17341 aaaaaatcaa tccctgtacc aaaagaacgc cgtaaaggta atgggaaagc aatcaagatc
    17401 actggtgctt cagaaaacaa tctgaaaaat attagtgttg aatttccatt aggagaattt
    17461 gtagcagtca caggtgtgtc tggttctgga aagagtacat tggtcaatag tatcttaaag
    17521 aaatcgttag cgcaaaaatt aaataagaat tctgctaagc caggtaaatt caagacaatt
    17581 tccggctacg aaagtatcga aaagatcatc gatatcgatc aaagcccaat cggccggacg
    17641 ccgagaagta atccagcgac ttatacaagt gtatttgatg atatccgtgg gttatttgct
    17701 caaacgaacg aggcaaaaat gcggggttat aagaaagggc gttttagttt caacgtaaaa
    17761 ggcggtcgtt gtgaagcttg tcgcggggat ggaattatta agatcgaaat gcactttttg
    17821 cctgatgtct atgttccttg tgaagtatgt catggtaaac gatataattc tgaaacatta
    17881 gaagtgcatt acaaaggaaa aagcattgct gatattttgg aaatgacagt agaggatgct
    17941 gtagaattct tcaagcacat tccaaagatt catcgcaaac tgcaaacgat tgttgatgtt
    18001 ggcttaggtt atgtgacgat ggggcaacca gcaacgacat tgtccggtgg tgaggcacaa
    18061 cggatgaaac ttgccagtga attgcacaaa atctctaatg gaaagaattt ctatatacta
    18121 gatgaaccaa cgacaggact tcatagcgat gacatcgccc gcttgttgca tgtattacaa
    18181 agattagtag atgctggtaa cacagtttta gtgattgaac acaatctaga tgtaatcaaa
    18241 acagcagatt atatcattga tttaggacca gaaggtggag aaggtggagg aacgatcctt
    18301 gcgactggaa caccagaaga aatcattaac gtaaaagaaa gttatacagg tcactatttg
    18361 aaaaaaataa tggtataaag aggatagata gctgagatag ttaaaaaaac ataaaaaaat
    18421 gaatttttgc ttgttttatt aatatcagtg ttctagaatc attacatggt agttctttct
    18481 acactgattg gtatagataa aaacttccta taagttcaat ccgttcaaaa aagaattgag
    18541 caatcggagg actttccttt gattgctttt ttctttatgg tatgatattc cttgtgtagt
    18601 tggaaaagaa aaacaagaga ttatgagtaa gtgagagata atgatgaaca gtattgaaaa
    18661 tgaagaattt atccctatat tattaggaag cgacatgaac gtttatggta tggcacgttc
    18721 ttttaatgaa gcatacggca aaatctgcca agcatatgct tcggatcagt tagcccctac
    18781 ccgctacagt aaaattgtca atgtagaagt tattccagga tttgataaag accctgtatt
    18841 tatcgagacg atgcttcgtt tggcaaaaga aagatattct gataagagta aaaaatatct
    18901 tttgattgct tgtggtgatg gatatgcaga attgatctcc caacataaac aagagctgtc
    18961 agaatatttt atctgtccat atattgatta ttctttattt gaaaggctga tcaataaagt
    19021 aagcttttat gaagtttgtg aagaatatga tcttccgtat cctaaaacat tgatcgtcag
    19081 agaagaaatg ttagtaaatg gacatttgga acaggaattg ccttttgaat tcccagttgc
    19141 tttgaaacct gcaaacagtg tggagtatct ttctgtccaa tttgaaggaa gaaaaaaagc
    19201 ttttatttta gagactagag aagagttcga tttaatttta ggccggatat acgaagccgg
    19261 ttataaaagt gaaatgattg tacaagattt tatcccgggt gatgatagta atatgcgtgt
    19321 gctaaatgcg tatgtagatg aagatcatca agttcggatg atgtgccttg gtcatccact
    19381 attagaagat cctacaccag catcgattgg taattacgtt gtgatcatgc cagattataa
    19441 cgaaaaaatc tatcaaacca ttaaggcatt tttggaaaaa atcgaatata caggctttgc
    19501 caatttcgat atgaagtatg atcctagaga tggagaatat aaattatttg aaatcaattt
    19561 gagacaaggt cgtagcagtt tctttgtgac attgaacggc ttgaatctgg ctcgttttgt
    19621 cacagaagat cgagtgttca acaaaccctt tgttgaaacg acctatggaa cgaatcaatc
    19681 agataaagca agattatgga tgggtgtgcc caaaaaaatc tttttagaat atgctcggga
    19741 aaatgaagac aaaaaactag ctgagcaaat gatcaaagaa aatcgttacg gtactactgt
    19801 attttatgaa aaagaccgat caatcaagcg ctggttgttg atgaaatata tgttccataa
    19861 ctatattcca agattcaaaa agtattttca tgtgaaagaa ggctagttca tggagaattt
    19921 tttcagtatt ttaggcggaa tgggcacgat ggcgacagaa agttttgttc gcttgatcaa
    19981 ccaccgaacg aaagctacaa aagatcaaga atatttgaat tatgtcttat tcaatcatgc
    20041 aacagttcct gatcgtacag cttatatttt agatcgatca gaagaaaatc caatgccgtt
    20101 tctgctggat gatattgaga aacaaaattt attgcgacca aacttcattg tgttgacttg
    20161 taacaccgca cactactttt ttgaagagtt acaagcggca acggatattc ctatcttgca
    20221 tatgccaaga gaagcagcaa atgaacttgt ccgtcagcat acgacaggga gagtagcgat
    20281 tctaggaaca gaaggaagta tgaaagctgg aatctatgaa cgcgaagtca aaaatcttgg
    20341 tttcgaaaca gtgattcctg atactgcgct tcaagaaaaa atcaattacc tgatctatca
    20401 tgagatcaag gaatcggatt atttgaatca agagctctat tacgaaatct tagaggaagc
    20461 ggtagagcgc ctaaactgtg aaaaagtcat cctaggttgc acagaattat ctttgatgca
    20521 tgaatttgct gaagataatc attacccagt gatcgatgct caatctattt tagcggatcg
    20581 aacgatcgaa cgtgcattag ctgaaagaag cgaggcattg gatacagcat cggaaaagta
    20641 aaaaaattgg atttggggca aatatcctaa aagatatttg gtccaaatct ttttgtaaaa
    20701 gaaaaagaaa actggtaatg atacgcccgg gatgatataa ttttattatg cacaatgtga
    20761 gaggggttcg taaatatgac agataatttg caattagtca tcataacagg tatgagtggt
    20821 gcagggaaaa cagtagctat ccaaagtttt gaagatatgg gctatttttg tatcgataat
    20881 atgccgcctc gattgattcc aaaattctgg gaattgatca aagaatcagg taaagtcaca
    20941 aaaatggctt taggagtgga tttgcgttct cgttccttct ttgaagaaat ccaaaacatg
    21001 ctgatcgaaa tcgaaaatac gaacttcatc gacacttcta tcttattttt agatgcttca
    21061 gacgaagaac tagtggctcg ctacaaagaa acaagacgag cacatccaat ggcgatggac
    21121 ggtttgatca ctgaagggat acgtaaagaa cgggcgatac tagacgactt gaaagcccaa
    21181 gcttccgtga tcattgatac gacaacattg acaccacgac aattacgtga aaaaatcaat
    21241 gagtcattca aatcaaaggg agaccaagga tttcggatcg aatttgtatc atttggtttt
    21301 aaatacgggt tgccgatcga ttcggatatt gtgatggatg tgcgtttttt gcccaaccct
    21361 cattatatcc cggaactaag accattgacc ggaaaagatc agccagtcta tgattatgtg
    21421 atgtcctttg atgaaacgca atcattctac cataaatttt tggatcttct ggaaactgta
    21481 ttgcctggat acattaaaga aggaaaaagc agcttgacag ttgcaatcgg ctgtacaggc
    21541 ggtcaacacc gttctgtggc attgactgaa cgtttggcaa atgctttagg gaaaaactat
    21601 aaagtcaatg tgacacatcg ggacaaggat aaaaggaaag agacggtgaa ccggtcgtga
    21661 aaatgaaaac ctaccggata agaaaaccaa agatcgtagt ggtcggcggt ggcactggtc
    21721 tgccagttat cctgaaaagt ttacgaaatc aaggagcaga tatcacagca gtagtgactg
    21781 ttgcagatga tggtggaagc agcggtgcaa tcagagaatc gatcgctatg gctcctcctg
    21841 gtgacttgag aaatgtctta gtggcgttat cggatatgcc acaattctat gaagatattt
    21901 tccaataccg tttcaaaaag gaagatcagt ttttagccaa tcatacgatc ggtaatctga
    21961 tcattgccgc agtttccgag atgcggggaa gcacttatga ggcgattcaa ttattagcaa
    22021 aaatgatgca tgtagatgga catgtttatc cttcttcaga aactcctttg accttgcatg
    22081 ctgtttttaa agacggaacg actgcagtag gagaatctaa aatcgcgatc aaccgtaaaa
    22141 ccattgaccg tgtgtatgtc tgcaacacaa atgataaaag tgaagccaaa gcggctcgaa
    22201 aagtcgtttc agcaattatg gacgccgaca tggtcgtttt gggacccgga agtttattca
    22261 ccagtatcct tccaaattta gtgataccag aaatcggcga agcaatgctc aagacaactg
    22321 ctgaaaccgt ctatatctgt aatatcatga cccaaaaagg ggaaacggaa catttcacag
    22381 atgccgatca tatacgtgtt ttacacaagc atttgaatca gccttttatc gatacagtat
    22441 tggtcaatac ggaaaaagtg cctgaagatt atatggaccc agagatctat gatgagtatc
    22501 tagtacaagt cgcacacgac ttcaacggat tgagaaatga aggatgtcga gtgatttcca
    22561 ccgacttttt agaattgaaa gatggtggtg tcttccacga tggagacaaa gtagtagaag
    22621 aattgttccg tttagttttc ggttcaaaat attaagcaat ttattgttgg agaaaggagg
    22681 agaataggat gtcatttgct gcagatgtga agaaagaact aactggtttg gaagttcatc
    22741 gagaacatgc gaaagcggaa ttagctgctt tgctgcgaat gaacggctct ttaggtattg
    22801 tgaaccagca gtttattttg aacgtccaaa cagaaaatgc tgcaattgcc agacgtatct
    22861 attctctttt gaaagatcat tatcaggtac gaagtgagct actcgttcgt aaaaaaatga
    22921 aattaaaaaa gaacaatgtc tatatcgtcc ggttgaagca aggcacaaaa gatgtgttga
    22981 tggatcttga tatcatggat ggtatgatgt tcaatggaca cgtttcggac gagattatgg
    23041 gaaattcgca aaaaatgcgt tcttacttac gtggtgcttt tatggcctca ggttcagtca
    23101 ataatccgga aacgagtcgt tatcatttgg aaatattttc tatttatgaa cagcataacc
    23161 aagacatttg cgatatgtta aattattacg gtctacatgc tcgaacgctt gaacggcgca
    23221 atggctatat ttcgtattta aaaggagcag aaaaaattgc tgatttctta acattgattg
    23281 gtgcaaccaa ctcaatgctc cgatttgaag atgttcgaat cgtacgggat atgagaaatt
    23341 cggtcaatcg tctagtcaat tgtgagacag caaatctgaa caagacgatt gatgcggctt
    23401 ctaaacaaat cgaaaacatc gaattgatcg aagcaaaggt cggtctacat gcccttcctg
    23461 aaaaacttca ggaaatcgca gaacttcggc ttcaacatcc agaggtcagc ttgaaagaat
    23521 taggggaaat gattccctca ggtgcaatat caaaatcggg aattaatcac cgaattcgca
    23581 aaataaatga atttgcggaa aaactgcgtg aagaagcagt ttaatccaaa gaaaaaactg
    23641 atacatgaag caggagatgc gaatgtatca gtttttttta aaagctatac ttgcttttct
    23701 tccgtcaaac tataattcca actttactgg agtaacataa tgttgaaagg cttctattgt
    23761 tttttaatac aatcgtataa aaagcgggga gacaactgaa tgaagatttt agttttatac
    23821 ataaactttt gcttaatata gaagtcctga tatagatagg atcaagtatt tatctataac
    23881 tggagattaa ttaaaaactg gaaggaactg ctcgatcaac cttgagaact gtttttctta
    23941 cttctggtca agattctcgt ggttggtgga taaggatggt tgataagttc attggattag
    24001 ctagtcgaaa acaaccaggt gtaattaatg tagaagtttt aacaagggga tggagtgatt
    24061 tattcagtga taatcataag ttcataaata gtaattggga tgtatggttg gtatacgtta
    24121 tacctgaact tgaactatca agatttggtt tagaatttga gaatcgatgt ttataaaggg
    24181 agggcaaaaa atgtgctttt ttacaacttt tactatcatt atgattgcag tactttttat
    24241 ttttctagat atagcaaagc gaaatacagc atttttatta tatcgggttt tacttcgagc
    24301 aggtctcata acatttatat cgatcgttgg attttttcta ttcacagtta ttgtatttat
    24361 ttggagaact acagcaccac cattgccaga gattacatat ggagaatttc cgtttagtct
    24421 tgaatatgaa atagatgagg aaagaatttt gattgaagat acggtgattg cagaatttat
    24481 aggaagtttt agagggaatg tgacaactca acctagacga agttggagta taaaactttt
    24541 aaataatagt ggagagttga aagcatttca ttatgaattc ttaataatag aaagtgaaga
    24601 tgtaacaatc actttaagta gtggctctgc tggatatttt atgaatgatg gtggaagcaa
    24661 gccacagctc acagtccgtg atcgtattgc aggttttatg catttttctc actatgactt
    24721 agaagaagct cgtaaaatac ttgcagaata tgggatcaca ttaatcaatt gggaatatgc
    24781 gccaccgata agaaattttt tcaatgatta ttattagtct tataaaaaac agaatgtaaa
    24841 atttatgtgc gcgagtattt agttttccat tttttgtttg atagatatat agcattgttg
    24901 aagcatggga tagtggtgcc aattttatca atgaggttgg tcaggcagtt aacataattg
    24961 gtgatgctat aaatccattt aattggaatt ggaggaatta ggtgtggaaa cagtgagatt
    25021 atggatattc atgaaaaatt ttcgttcggc tttgagatat gttattctgg aatcaaaatc
    25081 aggttattat ctgattgaca cagatcacta tactttttgg ggaggctacc tttttccgat
    25141 ttttaattgg ataatccccc ataaggttat gaaaattaac ttgcctgcag aagaaataaa
    25201 tagattaata ctcaacaaag atttacaaag gaaaagagag aaagaacatt ctaatgttgc
    25261 ttggataggt ccagcatttg cagtagtgac ttcttcaatt gtcggtccta tgctagagag
    25321 tatttatagt gatttttcta ttggaatacg ttatttattt gttactttaa gtatagctgt
    25381 tcttttgtgc ataaagggtt atgttagcaa gaagaataaa gatattttaa cactaatcgg
    25441 tgtaaacaat ttatctagta ctaaaattat actgtttcct gaatctataa aagaaggatc
    25501 aaggttgttg ataattttta taatgcttat actgttttct gttttatttg gggtgatgtt
    25561 tata
//
LOCUS       DAFTHM010000030        25388 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFTHM010000030 DAFTHM010000000
VERSION     DAFTHM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.030"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            135..2606
                     /locus_tag="L7C88_001256"
     CDS             135..2606
                     /locus_tag="L7C88_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBP9558099.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2709..4445)
                     /locus_tag="L7C88_001257"
     CDS             complement(2709..4445)
                     /locus_tag="L7C88_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBP9558100.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4442..5146)
                     /locus_tag="L7C88_001258"
     CDS             complement(4442..5146)
                     /locus_tag="L7C88_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9558101.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5277..5780
                     /locus_tag="L7C88_001259"
     CDS             5277..5780
                     /locus_tag="L7C88_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBP9558102.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5740..6078
                     /locus_tag="L7C88_001260"
     CDS             5740..6078
                     /locus_tag="L7C88_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBP9558103.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6099..7517
                     /gene="ffh"
                     /locus_tag="L7C88_001261"
     CDS             6099..7517
                     /gene="ffh"
                     /locus_tag="L7C88_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBP9558104.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7629..8207
                     /locus_tag="L7C88_001262"
     CDS             7629..8207
                     /locus_tag="L7C88_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBP9558105.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8211..8732
                     /locus_tag="L7C88_001263"
     CDS             8211..8732
                     /locus_tag="L7C88_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBP9558106.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8811..9365)
                     /locus_tag="L7C88_001264"
     CDS             complement(8811..9365)
                     /locus_tag="L7C88_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBP9558107.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9618..9893
                     /gene="rpsP"
                     /locus_tag="L7C88_001265"
     CDS             9618..9893
                     /gene="rpsP"
                     /locus_tag="L7C88_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBP9558108.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            9905..10156
                     /locus_tag="L7C88_001266"
     CDS             9905..10156
                     /locus_tag="L7C88_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBP9558109.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10281..11072
                     /locus_tag="L7C88_001267"
     CDS             10281..11072
                     /locus_tag="L7C88_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558110.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11242..11763
                     /gene="rimM"
                     /locus_tag="L7C88_001268"
     CDS             11242..11763
                     /gene="rimM"
                     /locus_tag="L7C88_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBP9558111.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11753..12514
                     /gene="trmD"
                     /locus_tag="L7C88_001269"
     CDS             11753..12514
                     /gene="trmD"
                     /locus_tag="L7C88_001269"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBP9558112.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12650..12997
                     /gene="rplS"
                     /locus_tag="L7C88_001270"
     CDS             12650..12997
                     /gene="rplS"
                     /locus_tag="L7C88_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBP9558113.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(13129..14265)
                     /locus_tag="L7C88_001271"
     CDS             complement(13129..14265)
                     /locus_tag="L7C88_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBP9558114.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLQKPDLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKIPETYIVSGINTVDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PINEVVIDYKRESKTIKIKDKFLEDDEYKRLVNFTTSHNKRYSLLFQWLYLTGMRPGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPNGQFLFQTTKGTPFQLTAINTYLRNHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(14381..15295)
                     /locus_tag="L7C88_001272"
     CDS             complement(14381..15295)
                     /locus_tag="L7C88_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBP9558115.1"
                     /translation="MKKIVFGLLFLGLVLSGCSTSPNSASTKENTVSSTSEYETKKLT
                     SSDVHKIKVGDDLTQVYQTLGSPLRKWTNDFVYKELDNAITRDELIVSISKDAQGDYY
                     KEHSELIEHGNSAKDIKKLEMLQYTYSTDSDDETMLIWVSPKTEQVVYYNQRTFLDKD
                     GKSKDSSSTTTTTTTSSSEPQTASVAHSIGEAVPFTSENGNSINVTVQSVSKDYGDDF
                     YKPEGLFYAKVDFLVENTGTTPFDASSSYLEFYDSSDIKSDLASRDYFSETIQPGKSA
                     QGTAYFEVKNDGTTFEVFFADTSWKGSY"
     gene            complement(15386..15814)
                     /locus_tag="L7C88_001273"
     CDS             complement(15386..15814)
                     /locus_tag="L7C88_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBP9558116.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRGRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKRIEELKNLYGLPESAYRFLI"
     gene            complement(15819..16193)
                     /locus_tag="L7C88_001274"
     CDS             complement(15819..16193)
                     /locus_tag="L7C88_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9558117.1"
                     /translation="MSLVTKIKELADEKHVTIAEVERQVGISNGQIRRWDKASPKSEN
                     LKKVADYFGVTTDYLLGNNNVPKWATKEEVVELDKLLDSNVNMSYGGETLTPEQIQRV
                     KDILIATFWDIVKEDKEKGKKM"
     gene            16497..16682
                     /locus_tag="L7C88_001275"
     CDS             16497..16682
                     /locus_tag="L7C88_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9558118.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALIGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            16696..16944
                     /locus_tag="L7C88_001276"
     CDS             16696..16944
                     /locus_tag="L7C88_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558119.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKVTPKEFIEKHLVDL"
     gene            16975..17154
                     /locus_tag="L7C88_001277"
     CDS             16975..17154
                     /locus_tag="L7C88_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558120.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFIGLDE
                     AEYKTKKASREGLTR"
     gene            complement(17274..17852)
                     /locus_tag="L7C88_001278"
     CDS             complement(17274..17852)
                     /locus_tag="L7C88_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558121.1"
                     /translation="MVVFSMNYILYVLLVVYAIIYIKQIVNAVSEITTINYLLTTIEK
                     VINDLKRLNDHSGSYKSDPYFQNNVTPIREIMVKEMPRINKVLPYSLVTLSLNQSDDI
                     LEENFRIIASQIFDKNNEIHYRKFWFLNPLIALKKFFLLPSEILSWFGINLSTFPGRI
                     FSLVIWVTSLFAQETISQILSFVITHFFKGQK"
     gene            18007..18324
                     /locus_tag="L7C88_001279"
     CDS             18007..18324
                     /locus_tag="L7C88_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558122.1"
                     /translation="MLIATDTLDRIFLKDEYKLRNIDASGILVFDLYDNGKIGIYQAS
                     DIEETNLAFEQIDDSVELDLDEAILAFEQIAKLLKEAQKNGNSLPTQRVIYQSPGTGR
                     TIG"
     gene            18257..18736
                     /locus_tag="L7C88_001280"
     CDS             18257..18736
                     /locus_tag="L7C88_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBP9558123.1"
                     /translation="MATLYQLSESYIKVLELAEQLDEEILRDTLDSINEAIEYKAENL
                     AKIVKEVEGKAELIDSEIKRLQERKTSLLNNAKSIKHYLQEEMEKTGKTKIKGELFNI
                     GIQNNPVSVNVINENLIPKGFFTPVPPKLDKKQLKEELKHGDIPGAELVQTKGLRIR"
     gene            18753..18929
                     /locus_tag="L7C88_001281"
     CDS             18753..18929
                     /locus_tag="L7C88_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558124.1"
                     /translation="MEHENVKDALKAAIEIAEAKGIKVDGKPATVHDIQNLTKEHLYF
                     IADLLGLSELYLDK"
     gene            19186..19617
                     /locus_tag="L7C88_001282"
     CDS             19186..19617
                     /locus_tag="L7C88_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558125.1"
                     /translation="MKNKLAKTTAIIGLALGSGVIGYAASNAFQDLDTIKANFNTVLQ
                     YGQTKSQRVSELESQLSNNTRTQEQLKAEIEQIKSDKQKEIEAKQREVEQKQQEIATK
                     QQEADSLRQQLSTVQNDKEQLEQRVSELRQYTDQKVGELGK"
     gene            19623..19940
                     /locus_tag="L7C88_001283"
     CDS             19623..19940
                     /locus_tag="L7C88_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HBP9558126.1"
                     /translation="MTIYDPNISWAKHTIKVSFMIWGYKGYVTYKVGGNTKGLSLIAI
                     DSDDLYDANFEDNPVNFRDLDEDWFSMELTNDKGDSTLVEDEFDRLGDYIVGVEIIAH
                     EPE"
     gene            20059..20745
                     /locus_tag="L7C88_001284"
     CDS             20059..20745
                     /locus_tag="L7C88_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9558127.1"
                     /translation="MQIKKATDIEQTKGTYLIYGAPGKGKTSTAKYFPGKTLILDIDR
                     TSKVLRGEKNVDIVYIDNEDTWNDWGNTLADLTTNYVGVYDNVVVDNVSELERCILSS
                     LGAEGKNNGVPSQGDYQYMQFRMVNSLRYMKNLDSNLIWTAWEEIDLWTDSDGSSYNI
                     ALPQINRKIRNNILGLCDVVGRLMVKEDDERGFILQATDSTYAKNQLDNRSGCKQSEL
                     ILDGIVRLPE"
     gene            20720..22069
                     /locus_tag="L7C88_001285"
     CDS             20720..22069
                     /locus_tag="L7C88_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBP9558128.1"
                     /translation="MELYDYQNDLVDRARQAYVDGYKAPCIVSPCGSGKSVMVAEIAK
                     RTTRKGNRVLFLVHRRELIDQIKDTFQKMGVDNQLVNFGMVQTVVRHLKTIKKPQLII
                     TDENHHGLAASYRKIYEYYSDVPRLGFTATPIRLNGSGLGDVNDLLIEGVSAKWLIEN
                     HRLAPYEYYAPKLIDTAELKKASTGDFTKKSMDKAVKNTIYGDVLKHYKTLAEGEQAI
                     AYCHSIDASKHTAEIFNDAGYKATHIDAKTPKDERADIIEAFRNHEIKILCNVDLIGE
                     GFDVPDCSTVIMLRPTQSLSLYIQQSMRGMRYRPDKTSIIIDHVGNVNRFGLPDMDRE
                     WSLDTKKKTKTDSDLSIVQCAFCFGAYERPKGDNICPYCGELQPIEERKSELEIDESA
                     ELMKVGETKITLNFENNKYYNMTEDEAESIEDLYAIARAKGFKPGWAYMAAKRKGWL"
     gene            22060..22533
                     /locus_tag="L7C88_001286"
     CDS             22060..22533
                     /locus_tag="L7C88_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBP9558129.1"
                     /translation="MVVGMGGIFGKKAEDVQGSIINGVTIIGDTGKRDSSGNQIVIAR
                     NKNNEVFESSLSNIKRGVVNGTGEESGYVNLKKANEKYHVEGTYVKALSVGGTKGVNW
                     DKRRNKWKARLYFKGEYVLQKDFNTKEEAIQARLAAEEKYFKPILEKYENKKEND"
     gene            22508..23035
                     /locus_tag="L7C88_001287"
     CDS             22508..23035
                     /locus_tag="L7C88_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HBP9558130.1"
                     /translation="MKIKRRMINMTGFNLDFSKAQQGNEIKDGTYEVVVNKAVENATK
                     SGAEFIDIDLIVRNDVDQPFQNKHIFAKIWKAKATGKYNEGMIMAIAQALQLEDGKSY
                     NGFDELLADFVLKTASVRVKTEESNGYKNVNVKSWDKTNTRGVMNHQFKNGDEPSFGP
                     ERSRATTVRNDNLPF"
     gene            23050..25362
                     /locus_tag="L7C88_001288"
     CDS             23050..25362
                     /locus_tag="L7C88_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBP9558131.1"
                     /translation="MYEKIPKELKNLKQWCVYKLVWDEKRQKHTKIPYNANNGHKAKS
                     NDESTWSDFQTALAAIDHYGMSGLGFFFKPPYFGIDIDNAEGEVERFKSGDIEENIIY
                     EFIESMRSYAEYSQSGTGIHIIARGELPGGRRRKGDVEMYQNGRFFVMTGNAASKYLE
                     ITEPNPKDIKRLYDRYVGDEKIIQFKEENPLMNTVDLPVEEIIKRAESSSQGARFKVF
                     MNGGWEAFYSSQSEADMAFANDLAFWTGRDFEKMDEIFRASAMIRSKYDQKRGSATYG
                     ESLLNKAIADTNSVYNPKRKSDFKIFIKDQEQPKEEKYYSYDDTGNADRFTDIYGTLV
                     KYSYIDKSWYYYDGKVWLQDNTGEVRKMIDTTVDIMGKEPLTIPEGADDETKEALMKA
                     KEKHVKRSRSNAGKNAMMDELKHRLSVLPEEFDKDKTLFNTQSGYLSLHDGLLHEHEI
                     DKMFTRVSNVEYTESVDCPMWEEFINQIFDNDQELIRYIQKCVGYSLTGSTREQCMFI
                     LYGHGSNGKSVFLEIISELMGNYAMTMQAQTIMVKQSQSSANSDIARLKGARLVTSSE
                     PNEGVRLDEGLVKQLTGGDKVTARHLYGKEFEFEPEFKLWLATNHKPIIRGTDDGIWR
                     RLNLIPFTVQIPDHKKDKNLKFKLQTELQGILKWAIDGCLLWQREGLEKPKSVVAASQ
                     DYRNEMDQIGTFIETCCETGPGLKISGGELYKVYREWASDNGEHTFTNTKFGREISKK
                     YSKEKAGGFMVYKGITLKPRKYDNVRELFK"
BASE COUNT         8485 a         4461 c         5180 g         7262 t
ORIGIN      
        1 cctttttttt tgctatatga caggaatgaa aggtgtttgc aagcttaatg tgaggaacac
       61 tttccatatc tgttctatac tggataggag aagtttggaa atatccagaa aacgaaatca
      121 atcgaggtag ccacatgaag aataaatgga taaatcgaag taaaaaaaag aaagtaacac
      181 aaagatcatc agataaagtc atccgtcttt ttccatcgta taaagaagga ttaacggcag
      241 atcaagtcaa ggaacgaata gaaaaaggtg cagcaaataa ttcagtcgat cccacattca
      301 aaacaaatca gcaaatcgta ttggaaaaca tatttacgta tttcaatttg atctttctta
      361 tcttagccat tttgctttgt ttagtagaat cctataagaa cttgactttt ttaccagtta
      421 tcatagccaa tacaggaatc gccatttttc aggaaattcg atccaaaaag atcttggacg
      481 aactaaatgt tttaaataca gcaaaagtca atgtcatacg agacgggata gaacaaacaa
      541 tagatataga agaccttgta atagatgaca ttgttatttt agagactgga tatcaaattc
      601 cagcagatgc agaggtcgtg gaagggaaac tgcaagttaa tgaggcttta ttgacaggcg
      661 aagcagatga aataaccaaa gaaataggtg atccattaat gtccggcagt ttcattgttt
      721 ccggaaaagc ttacgcccga ttagacaaag ttggagcaga ttcgtatatt tcccagctga
      781 cagtcaaagc caagacaatg ggagaaggag aacagtcgga gatgattgct tctcttaatc
      841 aattgatcaa atggattggg atcatcatta ttcctatcgg tatcctgctt ttttctcaaa
      901 gttacttttt taatggaaac acgatcaaag aaagtgtcgt tgcaatggaa gcagcattga
      961 tcggtatgat acctgaagga ctgtacttgc tgacgacgat tgcattagca ttaagtgcga
     1021 ctaaactagc aaagcaaaga gttcttttac acaatatgaa aagcattgag acattggcaa
     1081 gggtaaatgt cctttgtgta gataaaacag gaacgatcac agaaaataaa atgtctgttc
     1141 aaaaaatgat cgtctctaaa aaacaagaaa taatcagtca gtcagatcaa ttggaagcat
     1201 gcattgctga ctatgcaaaa gcgatggcag gagacaatgc aacaatggaa gctgttaaag
     1261 catattttac aaaaaccact gatcaatcct atcaccatgt tattcctttt tcttctgtcc
     1321 aaaaattcag cagtgtagcg ttggcagaca aggtgtatgt tttaggagcg cccgaaatgg
     1381 ttttgcgcga tcaattgccg gaatatgcgg aagagtttgt ttctttcgct gaaaaaggct
     1441 atcgcgtgtt ggtctttggt gtgtacgatg ggattcttga agaaccagta ttgacagaag
     1501 cagtcacacc attaggctat attctgattg ctaatcctat cagaaaagaa gcaagagcca
     1561 catttgatta cttcaaaaaa cagcaagtag ccatcaaagt gatttctgga gataatccgc
     1621 tcaccgtatc caatgtagct gtccaagcag ggatttcaca tgctgatcag tacgttgatg
     1681 catctaaatt atcagaagaa gaatatgaag cagctgtcga aaaatataca gtttttggac
     1741 gcgtcaagcc agaacaaaag aaaatcttcg ttcaattgat aaagcgtaac aatacagtag
     1801 ctatgacagg tgatggcgtg aatgatattc tagccatgaa agaagcagac tgcagtatag
     1861 cgatggcttc cggaaatgaa gccgccatgc aggcctcaca agtggtctta cttgattctg
     1921 acttttcacg catgccagaa gttgttgcag aaggacggcg cgttgtgaac aatattgagc
     1981 gatcagccag cttgttttta gtgaagaata ttttctcctt tttgctctca ctgttttcag
     2041 tgatctttgc tctgacctat cctttagaac catcacaaat cacattgatt agtttgttta
     2101 ctatcggact tccatctttc ttgcttgctc tagaagaaaa caaaaagcga atcagaggga
     2161 aattcatcat gaatgtgatg gaaaaagctg tgccaggtgg actaacagat atgatcgtag
     2221 tcggtgcgtt ggtgatctgc ggggtgactt tgaatctaaa taaaacagat gtttctacag
     2281 catctaccat gcttttgatt gcagtagggt tcctcgttct ctataaaatc tgttcaccgc
     2341 tgaataaatt cagaagtcag atcattcttt tctgtgctag cggtaacttt ttttcggtca
     2401 tctttttgca taagctgttt tcaatcaccg gtatctcagc tgtatcactt ttgctgttga
     2461 gcattctatt tttctcggca gattcgattt ttaggcattt gaccacattg gtagaatatt
     2521 tgtttgaacg taaaaatgaa aaagagcaaa agccgtttag tcgcgtagct aaaaaatttc
     2581 tatcgatatt taaacgagaa aattgacgaa aagtatctca aaaaagagta aaaaagaaca
     2641 accactcgtg tatctttcga agcaggatga gtcatccaac tttaaaacgc acgagcagtt
     2701 gctctttttt acattttcgg aatggtaacg gtgaaagtcg aacctgttcc aagatgactg
     2761 tctacagtaa tcgtaccatt aaggagttgc acgtagtctt ttacaatcgc taaccctaat
     2821 ccggtcccgc ctgaatgtcg gcttcgcgcc ttgtctacgc ggtaaaaacg ctcaaagatc
     2881 cgttcctgat cctcaatgtc gatacctata ccaaagtctt ggacagaaaa cgatagatca
     2941 tctgttgcct gatagcggat aataatctcg ctgtcgcttt ttgaatattg gacagcattt
     3001 tcaattagat ttttgataat tggataaagg atatctgttt tagtagtaaa tggttcgttc
     3061 tttccaatca atcgaatcgt caaccgtttc ttttcgatga ttggctgata attttgaacg
     3121 atttgctgga aataaggttc tgtataaatt gtctggatct cgtaagaatt ctcgccatct
     3181 tttgacagct ggatgatttc ccgaatcagt ttatctaacc ggatcgcatc tttttgcatg
     3241 atctcaagaa aagaagtcag agtttgcggg tcatcttttg caccatccag taaagtctcg
     3301 gtaaaaccaa tcagtgaagt cacaggagtt tttaattcgt gagagacgtt gccaacgaaa
     3361 tccttttgta gcttttctaa acgtcgcact ttcgttaagt catacgccac ccctagaatc
     3421 tgtccggtac cttctgaatt agtaaagtag cgcaaactca agtctaatgt ctgccgacct
     3481 tctgtaaggg tgatctcctg atggatcagc ggatgctcag gagtcacttg atgaatcagc
     3541 tgaatgagtt ttggctcttg aatgacttct gtgtaccgct gttcaggttg atagcttacc
     3601 acgtttaaat gtagctgcat ctttggatta agcagtagta aacgagaatc agcatcatca
     3661 atcaggaata cgccaatcat cagttcgttc agtaacgtat ataattgctc ttctgtggta
     3721 gtacacgccc gatacatctt actcatttgt tcgctcaacg cattaatcgt ctgatacaat
     3781 tcttcccatt gatcgggtgt ttgcatgatt acttccgcct gattaggatt ttgcaccatt
     3841 ttttttagta cgggcagcac ggttttcaat ggctggtttt tttgatagat cagataatag
     3901 atcattcctg caagaacaag gaagaaagac agaaagaaga aaaagaccca acggcgaaaa
     3961 ctctcagttc tcggtaaaaa accgcttgtc ggttctgcga tacgtaaaat ggcttctaac
     4021 tggccacttt ttttgactgg taatgcgaca tataaaagat cctcattcaa agtagtactt
     4081 ttgcgcaaag cgctacctag gttcccacca ttcaatacgg ctttgatttc gggacgggag
     4141 tttcgctgtt cattcaatgt ttcattgttt gtgtcaaata agatctttcc agtagcatcc
     4201 attaaagtaa tccgttcgtt cgactgatgg acgaattctt ccaaagcagt tttgttttgc
     4261 gctgcttgga ggttttcgac atctaattgc cggatcagca gttgtgcttt ttttgtcagg
     4321 tagctttctt gctgttccac gatctgctgt tgaaaataat gggaaatcaa ttgccagcca
     4381 ccaaaaaaca aactaactaa aagaataaga aagaagagac gttcataaat ttttttccat
     4441 ttcatcgttt gggttcctga aacttatagc caaatcctct aatagtcacc aagtactttg
     4501 ggtgttttgg atctcgctcg attttttctc gcaaatgact aacgtgtaca tctacgattc
     4561 ggctttgtcc tgcgaagtca aaattccaaa tgcggtctag caatgtgtct cggtcgatca
     4621 cacggtcttt tcgtttcatg aaataaacaa gtaattcaaa ttctttcggt gttagttcaa
     4681 tcagatggtc gtctacggtc acttgataat tggtcaaatc agcagtgatt tgtccaatcg
     4741 atagatattc aggctcagct tcatcttttg attgcttacg aggttcaatt cgtctgaata
     4801 ttgctttcat acgggctaat acttcgcgag gactaaatgg tttggtcaaa tagtcgtcag
     4861 cacctatttc taggccaatg atccgatcca cttggtcatc tttagccgtc agcatcaaaa
     4921 tcggtgtttc atttttttct tgacgcagcc gctgagtgat ctccatgcca tccatcgttg
     4981 gaagcatcac atctaaaatg atgaaatcaa atgattgttc taatgctaat tctaatcctt
     5041 cgcctccatc tgtggcactg gttaccttgt agccttcttt ttccaaattg aacgtcaaga
     5101 gcgttacaat agaaggttca tcatcaacaa ctagtatttt tttcattcaa atctccttta
     5161 aataggtttc attctgttta tattttagca tagaatcagt acaaagggct attttacaaa
     5221 agaaataaat ggtataatag gaaggcactt tgctgaatag aaaggaagag cagtcaatga
     5281 ttggaatcag tgcatgttta ggcggtctgg cctgtcgcta tgatggacag aaaaaagaag
     5341 taccagaatt gatggaacta gttgaaactg gagaagctgt catggtctgt ccagaagtga
     5401 tcggcggatt accaattcct agagatcccg ctgaaatcat tggtggaaat ggattcgatg
     5461 tgtggaaaga tcaagcaaaa gtatggacga caagcggcga agatgtaacg gaagcgtaca
     5521 aaaatggcgc gatcaaagcc tatcaaaaat tgcaggaaaa acacattgat ctagtcatca
     5581 tgaaggaaaa aagcccttca tgcggaaccc attcgattta tgacggaagt ttttccggaa
     5641 taaaaaaaaa tggtgccgga gtggctactg cttattttat tcagcaaaaa atgactgtgc
     5701 tctctgatga agaatggctg aaaactagag gtgagcagaa tggaaatcga aaagaccaat
     5761 cgaatgaacg cgctctttga attttattcg accttattga cagaaaaaca aatgaactac
     5821 atggaattat attatgcaga tgatttttca ttaggtgaga tcgcggaaga atacgaagta
     5881 agccgacaag cagtatatga caatatcaag cggacaagca agatcttgga ggattatgaa
     5941 aaaaaactcc atcttttttc taattatatt gttcgagaac aggtattgga aaatatgact
     6001 gcatatatta cagataagta cccggaagat aaaaaactac ttgaatatgt acagcaaatt
     6061 caagcaatcg aagaataaat aaaaggaatg aagaaaatat ggcatttgaa agcttaactg
     6121 aacgtctcca gcaggcgatg ggaaaaataa gaaaaaaagg aaaagtatca gaagctgacg
     6181 taaaagaaat gatgcgggaa atccgccttg ccttactaga agccgatgtt aacttgcaag
     6241 tagtcaaaga ttttactaag cgcgtacgcg aacgtgcggt aggggcagaa gtgctggaaa
     6301 gtttatcacc tgcacaacaa atcgtaaaaa tcgttgatga agaattgacg atcacacttg
     6361 gttctgaaac agcagagtta aataaatcac caaaaatacc aactgttatc atgatggctg
     6421 gtcttcaagg ggcaggtaaa acgaccttta ctggtaaatt agccaattat ttaaagaaaa
     6481 atgaaaatgc tcgtccgctc ctaatcgcag gggacgtata tcgaccagct gcgatcgacc
     6541 aattgaaagt attaggtcaa cagctagacg ttcctgtatt tgatatggga actgaagtca
     6601 gcccggtaga gatcgtccgt caagggatgg agttagcaaa agaaaagaaa aacgactatg
     6661 tattgatcga tacggcagga cgtctgcata tcgatgaaac attgatggat gagttgaaac
     6721 aaatcaaaga attgacgcaa ccaaatgaga ttttgcttgt tgtcgatgcc atgactggtc
     6781 aagatgccgt caacgtagct gatagcttca accagcaatt aggtattaca ggggtcgtca
     6841 tcactaaact tgatggggat actcgaggcg gggcagcact atcgatccgc tcagtgacag
     6901 gcgcaccaat caaattcatc ggttctggtg aaaaattgac tgacttagaa gtattccacc
     6961 cagatcgtat ggctagccgt atccttggta tgggggatat gctgacattg attgaaaaag
     7021 cgcagcaaga ctacgacgag aaaaaagcgg aagaacttgc acagaaaatg cgggaaaatt
     7081 cattcgattt caatgacttt attgaacagc ttgatcaagt gatgggtatg ggcccactgg
     7141 aagatctaat caaaatgatc ccaggaatga atcaagtccc tggaatcgaa aacgtcaagg
     7201 tagatccaaa agatgttgaa cgcaaaaaag cgatggttta ttctatgacg ccagcagaaa
     7261 gagcaaatcc tgatctgttg aacccaagcc gtcgtcgccg aattgctgcc ggttctggaa
     7321 acagtgttgt tgaagtgaat cgaatgatca aacaattcaa ggaatcaaga aaaatgatgc
     7381 agcaaatgtc caaaggggat atgaacatcc caggtatgga ccaaatgttt ggttcaggcg
     7441 tcaaaggaaa actaggcaaa atggcgatga atcgaatgat caagaaaaat aagaagaaaa
     7501 agaaaaaacg gaaataagat gaaaaaaaca gcttcggtac agactgaaaa tgtctactgc
     7561 cggagctttt ctatcagcaa tttttattct ttactaatac aattactcta aacgaagagg
     7621 tggcacagat gagatgtccg tggagtgaac aaacagaaag tatgcggcaa tatcatgata
     7681 ctgtctgggg tgttcctgaa tatgatgacc aaaagctgtt ccgaaaattg atgcttgata
     7741 ttaatcaagc cggattgagc tggcagacga ttttaaataa aagtgaagca ttcgatgaag
     7801 catatgatcg attcgatatc aaaaaagtcg caaattatgg agaaacaaaa atcagtgaac
     7861 taatggaaaa caaaggaatt attcgtaacc gaagaaaaat cgaagcagcc gtccaaaacg
     7921 ccaaagcagt cttgaaaatt caagaagaaa tcggcagttt ttcagagtat ctttggtcgt
     7981 tttctaatgg aaaaatcgtt gattcttctt atcattcaca agaagaagtc ccaacaacaa
     8041 gtcctctttc agatgaatta gcaaaagatc taaagaaaag aggatttaaa tttatcggaa
     8101 gcacaacaat ctatgctttt ttagaagctg tcgggatcat caatgatcac cttgacagtt
     8161 gtttccgcaa agaagaggtc gtacgtatcg gcagaaaggg cgaataaagc atgcgaaaaa
     8221 tcatatttta tggtgctata agtttagatg gctatttggc aacgaaaacg gatgatcttc
     8281 aatggctttt tgacactcca acaggtaagc aaactactta tgaagctttt tatgaaacaa
     8341 tcgatacgac catcatgggc agaaaaactt atcaggaagc aaaaaaatat ttggagaccg
     8401 aagcaattta tccagagaaa aagaatttcg ttttttccac ccacgcacaa ttacaattgc
     8461 cagatgctga ggtcgtaaac gaagatcctg ttgcttttct aaaaaatcta caaatgacag
     8521 aaggaaaaga tatctgggtt gtgggtggcg gtcgattgat caaaccgcta ttggaacatc
     8581 aaatgattga tgaatggtat atccagatta cccctgtatt attaggggac gggattcctt
     8641 tattccaaaa aggaacatat gaagcgcgtt ttgaaatgct agacacgaca cgattcggtg
     8701 aatttatcga attgcattat gtacgaaagt agaagtaaat aaaataaaaa aggcaactat
     8761 atgcagaaat gtcctgtaca tagttgcctt ttttattacc gttatgcttt ttactctgtt
     8821 aatttgttag aaaaatctag atacgcatct aaaatcgttt ggaagaaact taatgttcct
     8881 tcaacgatat taccattttc atcaattaga ttcgcaacgt ttccgatata tgcttccggt
     8941 tgctgcaagg ttggcacatt caaaaagaca agtgattggc gtagatggtg gtttgcgcca
     9001 aagccgccga tcccacctgg tgatgcagta acgactaaac ctggtttatg atcccaaaca
     9061 ctgtgtccat aaggtcttga gcctacatct aaagcatttt tcaatactgc tggcacagaa
     9121 cggttgtatt caggagtaac gaaaacgaca ccgtctagtc ccctcacttc ctcacgaaaa
     9181 cgagtccatt cagcaggagc ctgttctgga gtttcgagat cctcattgta aaatggcaga
     9241 tcatcgattt ttacaaatac actttcgtac ccttcaggaa gcaatttcgc aaaagcttct
     9301 gctacttttt tgttgtaaga atcttttctt aaactaccaa taaaaaatcc aatttttttt
     9361 gtcatacgat ttttcctcct tcaaactatc tataataatc ttacaaaaga taagtaactg
     9421 gagcaaataa aaacacttac tgacaaaagc tacatagaag atagattact tatttttaac
     9481 aaaaaagaag tctaaaatct tctattttct aaaaaaaatc gaatttaatc aagctgtaaa
     9541 gaaaaaaagc tttacagggt aaaaaaaaac tgttacacta catcttgtga ataaaacaat
     9601 ggaggtggaa ataaataatg gcagttaaaa tccgtttaaa acgtatgggt tctaaaaaga
     9661 gtccgtttta ccgtatcgtc gtagctgatt cacgttctcc tcgtgatgga cgtttcatcg
     9721 aaactgtagg tacttacaat cctttgaaag accctgcaga agtagtttta aaagaagact
     9781 tagttcttga ctggttatca aaaggtgcac aaccttctga cactgtacgt aacatccttt
     9841 caaaagaagg cgttatgcaa aaacaccacg aagctaaatt ctcaaagaaa taaggtgacc
     9901 ggatatgaaa gatttaagcg acttagtctt aacaatcgtt cgtccgctag tcacttatcc
     9961 tgatcaagtc aagttagacg tcgtagagtc gaaagacttt tacgagtaca atctaacagt
    10021 ggctcctgaa gatattggcc gtatcattgg aaaacaaggg cgtgttgcta aagcaatccg
    10081 cacaatcgtt tacggtgttc ggatcaatgc accgaaaaaa gtgcgtttga atatcatcga
    10141 tgataaggaa aagtaaataa acgtgctgta ctcgaatttt cgagtgcagc ttttttgttt
    10201 tttttattaa ttgaagaaat gattatttgg caaaacaagc aagaaagcgt atccttatag
    10261 gaggagggag tgaacagcca atgagaaaga aaatgttatt tattccattt gctctattgt
    10321 taagcgcttg tagttcggtt actcaagaat cagacaatac acatctatca agcagtatat
    10381 ctgaaactgt taccagtcca gaaaaaagta gtaccaaaac ggcttccacc actgaacaaa
    10441 caatggctac ctcaaataat gagaaaaaga ctgctttaga ccagttgaaa gaacaacagc
    10501 caaatgttcc catgcctcta gatgtaccag tctcttcagg ctatctcaat atcgcagcga
    10561 cacatacaaa gcaaggttat tctattttat attacagaac agatcgtccc ctcgggttga
    10621 atgctgacga attgaatcaa gaaacgccta ttgcaaccta tctatatcaa tatgggtttg
    10681 cttctagtca agaaacaatc caagttttgc agccatttga gatcgacaca aatggtcagc
    10741 aagtggactt aggttctcga atcacagggt atcagcaagg tgcagcaggt tcaagttttc
    10801 ttgaatggca agaaggaaac tggcgtattc gaatccgtgg gaataatata gaaggccaag
    10861 atcccttact attagctaaa gaaatcgtag cttatttgga agaaaacagt ctaccagcac
    10921 ctgaacaatt tggtaaaatt actgttgata tgggtgatac gacgaatcga gccgtagaag
    10981 taagctggca agaaccgaaa aatgcctata cgatcactca tcaagatcct atgtctgcgt
    11041 tgaagatggc agtttctatg aagaggttgt gaaatcagcg cgctgatctg agcccatcat
    11101 ttaactccaa gtcacaggaa gtaatcaaaa atagcacgcc gcatttttgc ataattttgg
    11161 cttaatacct taaaagaaaa ctagaattgc ctcttcacac atgctaaaat aaaacagaca
    11221 aaaaagaaat ggggatataa gttgactgaa tacttgaatg taggaaaaat cgtaaacaca
    11281 caaggtatca aaggcgaagt ccgtgttatc tcaacaacgg atttcccaga agaacgttac
    11341 aaaaaaggaa cggtgctaac actattccaa gacggaaaag cacctgtgga attaacagtc
    11401 aaaagtcatc gcaaacataa aaattttgac ttattgagtt ttgaaggaca tccttctatc
    11461 aatgatgtgg aaaaatatcg ggatggcata ttaaaagtgt caaaagacaa ctctgtagat
    11521 ctagctgaaa atgaattcta ttaccatgag atcatcggtc tgcatgtatt agaagatgga
    11581 actgagttag gtaaagtaaa agaaatcttg tcaccaggtg ccaatgatgt ttgggtcgtt
    11641 caacgtccga aaaaagctga tatattgctt ccatatatcg cttctgtcgt caaagaagtc
    11701 gatttagaag ctggagtggt ccgtgtagaa attccagaag gactgattga cgatgaagat
    11761 tgatgtattg actttatttc caagaatgtt tgaaggtcct atgggggaat ccatcatcgg
    11821 taaggctgta gataaaggat tattagatat caatatctct aacttccgcg attattcaga
    11881 taacaaacat cagacagtag atgattatcc atacggcggt ggagcaggta tgctgctcaa
    11941 agtccagccc atctatgata acatccaagc cattgaaaaa gctgcaccgg atgtcaaaaa
    12001 aagagtaatt cttcttgacc cagctggtaa acgattcgat cagaaaatgg cagaagaatt
    12061 ttcacaagaa gaacacttag tattcatttg tggtcattat gagggatatg atgaacgtat
    12121 ccgcacatta gtgacagatg aagtttcctt aggagattat gtccttactg ggggagaatt
    12181 aggtgcgatg gtcatgatcg atgcaacagt tcggcttttg ccagatgtgt tagggaatca
    12241 gacttcagct caaacggatt cttattcaac cggtttattg gaacatcccc aatatactcg
    12301 cccggcagaa tataaaggga tgaaagtacc agaagtattg acaaatggaa atcataaatt
    12361 gattgaagaa tggcaattaa aagaatcact aagaaggacc tatcaacgtc ggcctgatct
    12421 tttggaaaca cttgaatgga cacctcaaat gacgaaattt ttagaagaaa tcaagaaaga
    12481 agaacaagaa aaaacagcag atgaagccaa gtgacttttt ctaaaatctt ctttacagta
    12541 ggttgataat atgttagtat tttatggtga gtgcaaaagc acttaactat tacgatattc
    12601 cgctgtgaga aaagctcata agaatatttg gaataaggag aagaaaacca tgaatccatt
    12661 aatcgaagaa ttaacaaaag aacaattacg ttctgacatc ccagcgttcc gccctggtga
    12721 cactgtgcgt gttcacgcaa aagttgttga aggtactcgt gaacgtatcc agttatttga
    12781 aggtgttgtt atcaaacgcc gcggtgctgg aatcagcgaa acttatacag tacgtaaagt
    12841 ttctaacgga gtgggcgttg aacgtacatt cccattgcat acaccacgtg ttgcaaaaat
    12901 cgaagtagtt cgctacggta aagtacgtcg tgcaaaattg tactacctac gtgcattaca
    12961 cggaaaagct gctcgtatca aagaaatccg tcgttaatca tcgttatcag actgagaaag
    13021 aacccttggt attcaagggt tctttttttg ttctctgttt ttttatatta acgatttcta
    13081 tttgggacat ttttgattaa taaaaagggg caaaaaaggg gcaacaagtt acagtttttc
    13141 tatatcttct ttcaattttt cttttactcc ctttgtcaca tgcaaataaa tcttttcagt
    13201 gatatcacta ttttcgtgcc caacgcgatc ctgaatagca tacagaggag ttcctagttc
    13261 cgctaatttt gaaatatggg tatgtctaaa aatatgtgaa ctaagttttt tatcaatctt
    13321 catgtcagct ttatgatttc tcaaataggt gttaattgct gttagttgga aaggagttcc
    13381 tttcgttgtt tgaaatagaa attgaccatt cggatttaat tctagaagct cattgtaaat
    13441 agctatcgct ttttttggta aatcaatttc tcgcattcca gcagcagttt ttgtagaatc
    13501 agattttttc atatcagcta ttgaacgttc tctatacatc atcgtcccat ttataactac
    13561 tgatgcatta ttattggtaa tgtgtacatc gtctttactt aatgcgattg cttctccagg
    13621 cctcattcca gtcaaatata gccactggaa aaggagagaa tatcttttat tgtgtgaagt
    13681 tgtgaaattt actagtcttt tatattcatc atcttctaaa aacttatctt taatttttat
    13741 cgtttttgac tctcgtttat aatcaataac tacttcgttg ataggatttt tttctacata
    13801 gccttttttc atagcgtatg aaaaaagaag attcaatttg gatttaatta cactgacgta
    13861 cttatttgac aagtcatctt tatatatcat atcttcaaaa atattattta aatctactgt
    13921 attaatacca gaaacgatgt aagtctcagg tatctttttc tttatagtgt ttaagatatt
    13981 attcgtagga taatatgtag actccttaac ttgtcttttg taaataacta accattcttc
    14041 gacaagctca tgaaatgtta gatcaggctt ctgaagtgtt ttttcgttta attttatatc
    14101 aattttttta tttaactcta gcaatgccac tttctgagtt tctcgagatt tatttttata
    14161 agtaatgctc actttttttc tttttctagt ttttggatca atatatcgct cattatattt
    14221 atatactttt tttccgtttt tatcagtttt ggtttcaatc cacattgttt tcatctccta
    14281 tttgttgcta taataggaat ggataagtaa gccaattata gcaggtttat ttttcatcac
    14341 gtccacaaac tttggcgagg gagggggcgt gtttttttgt ttagtagcta cctttccatg
    14401 aagtatctgc gaagaacact tcaaatgttg ttccatcatt tttcacttca aaatatgctg
    14461 ttccttgtgc ggatttaccc ggttggatgg tttccgaaaa gtaatctcta ctagctaaat
    14521 cagatttaat atctgatgaa tcataaaatt ctaaataact tgaacttgca tcaaaaggtg
    14581 tagtccctgt gttttctaca agaaaatcta cctttgcgta aaataggcct tctggtttat
    14641 agaaatcatc accgtaatct tttgatacag actggacagt tacgttaata gagttaccat
    14701 tttcagaagt aaaaggaact gcttctccta tactatgtgc aactgatgcc gtctggggtt
    14761 ctgaagacga agttgtagtt gtagttgtag tagagcttga atctttggat tttccatctt
    14821 tatctaagaa agttcgttga ttataatata caacctgttc agtttttgga ctaacccaaa
    14881 ttaacattgt ttcatcatca gaatcagttg aataagtata ttggagcatc tctaattttt
    14941 ttatatcttt tgcactattt ccatgttcaa ttaattcaga gtgctcttta taataatctc
    15001 cttgtgcatc ctttgaaata gatacaatta attcatcccg tgtgatagca ttgtctaatt
    15061 ctttgtaaac aaaatcattt gtccatttac gtaacggtga accaagtgtc tgataaactt
    15121 gagttaaatc atcaccaact tttattttat gaacgtctga tgaagttagt ttttttgttt
    15181 catattcaga tgttgatgaa acagtatttt ctttagtgct agcagaatta ggactagtgg
    15241 agcatccgct taataccaag cctaaaaaaa gcaacccaaa aacaattttt ttcattttta
    15301 attcctcact tctatgatat gatttttttg taggatctta gaaataaggt ttttagtccg
    15361 tgttgcagca cggacttttt ttacattata taagaaagcg ataagcgctt tctggaagtc
    15421 cgtaaagatt ctttaattcc tcaattcgtt taggatattg atcattgtct tctttgtata
    15481 gagaaacaat gagattagca gcaaagcaat tagcttcgct ttcagatttg cttctagatg
    15541 ttcttgttga tacatagtaa ctggataagc cacgatgaaa aatagcgtga cctaattcgt
    15601 gagcgcaaat gtagaatctt tcctcagagt ctctcagttc atcatttaag aagattattg
    15661 cacgacctct aatttcttga aactgtcctt tgggattctc gataaaagga acgtattgaa
    15721 ttttaatgcc catcttttca caaatataaa aaggattagc ggactggtat ttccgcttca
    15781 actcctcgac taaattaatc gtatccatct ccataagctc acatcttttt gcctttttct
    15841 ttgtcttctt tcacaatatc ccagaaagtc gctatcagga tatcttttac gcgctgtatt
    15901 tgttcgggtg tcaatgtttc cccaccataa gacatattaa catttgagtc tagtagttta
    15961 tcaagttcaa ccacttcctc ttttgtagcc cacttgggaa cattattatt tcccaataaa
    16021 taatcagttg tgacaccaaa ataatcagca actttcttta agttctcaga ttttggcgag
    16081 gctttatccc atcttcttat ttgtccatta gagatgccca cctgtctttc tacttctgct
    16141 atagtcacat gcttttcgtc tgctaattct ttaatcttag taactaaact cattattatc
    16201 aacctttcaa agctgaaaag aaaataaata gcttaaaagt tatatttttg gttgacaatt
    16261 agcttttaag ctagtatatt taattcgtaa gctaaattgt tagctaaata agagcaacaa
    16321 aaaactctac taatttaaaa cattctctcg gtcgccaaac ttagaaatgt tattttagag
    16381 gctttttata agtcttattt aactatgtat tcataatagc ttaaaagcta ataggtgtca
    16441 acgatttagc taatttttta gcttacaaat tatttgttta gaaaggagct atttttatgt
    16501 ctgagaattt agacttaaaa attcgagcgg agatgagaaa aagaagaatg actttcaaag
    16561 aactagctgc gcttatcggt atttcaggag cttatttatc agatattcta aacggcaatc
    16621 gtgatggaaa gaaagcacaa cagcatatcg aaacagtgaa aaaaatattg gacatccgat
    16681 aggggggggt aggcgatgac aaaactaaaa aaacaagatt ttgtaaaaaa atataattat
    16741 tctccatcta cttatcaacg tcgaatgtcg gaactaaaaa atacagcaat tttctcagcg
    16801 gcgtatgaac gggtcacagg acaagaagtt tggatcaata cagaattata cgataaattt
    16861 ttgtctttca aatcctataa caggttacgc acaagaaagg taacacctaa agaatttatc
    16921 gagaagcatt tagttgattt ataaaaaaca gaacattttg agaggtgaag gttaatgggt
    16981 aaattcaaca gagcattagt attcagcgca ccgctaatcg tctatgcttt agggctttgg
    17041 ggaagtagac aagcgttgat aggaacgatt gtgtacatgg tttggatttt tatagggctg
    17101 gatgaagctg agtacaaaac aaaaaaagcc agtcgggagg gactgactag atgagaaaca
    17161 aaaaaatatc tctaacgcta ttaactatca tcacgattgt cgtatcgcaa ctattctttt
    17221 taactatatt aaacgacata tcgatgtcgg accgattgtt ggttcaatca gctttatttc
    17281 tgacctttga aaaaatgggt aattacgaaa gatagaattt gagaaattgt ttcttgggca
    17341 aataacgatg ttacccaaat tacaagacta aaaattcttc ctggaaaagt tgatagatta
    17401 atgccgaacc aactaagtat ttcgctgggt aagagaaaaa atttcttaag agcaatcaac
    17461 ggatttaaaa accagaattt tcgataatga atttcgttgt ttttgtcaaa aatttgagaa
    17521 gcgataattc taaaattttc ttcaagaata tcatctgatt gattcaagga aagcgttaca
    17581 aggctataag gcagaacttt gttaattctg ggcatttcct taaccattat ttctctaata
    17641 ggcgtcacat tattttgaaa gtaaggatca gatttatagc taccactatg gtcatttaat
    17701 cgtttgaggt catttatcac tttctcaatt gtagtaagta aatagttaat cgttgttatt
    17761 tcagacactg cattaacaat ttgcttaata taaattattg cataaacaac tagaagcaca
    17821 tacaaaatgt agttcattga aaacaccacc agtttttaac taaattatac caaaaaggag
    17881 agaagaaata atgcaagaat tagtaatttt gaaaaataaa aaaagacacg aacgccggca
    17941 agcatgatcg tgtcagggaa ataaactatc tttctatatt ttaccacaga aaggaatgaa
    18001 ccgtaaatgc taattgcaac ggatacacta gaccgcatct ttttaaaaga cgaatacaaa
    18061 ctgcgcaata tagatgcgtc aggaatttta gtatttgatc tttatgacaa tggaaaaatt
    18121 ggtatctatc aagcaagtga tattgaagaa acaaaccttg ctttcgaaca aattgatgat
    18181 tctgtggaat tggatttaga tgaggcaatc ctagcttttg aacaaattgc aaaattatta
    18241 aaggaggcac aaaagaatgg caactcttta ccaactcagc gagtcatata tcaaagtcct
    18301 ggaactggca gaacaattgg atgaagaaat tcttcgcgat actctcgatt cgattaatga
    18361 agcgatcgag tataaggcag aaaacttagc aaaaatagtt aaagaagtag aagggaaagc
    18421 tgagttaatc gatagtgaaa ttaaacgtct gcaggaacgt aagacatcgc ttttgaacaa
    18481 tgctaagagt atcaagcact atttacaaga ggaaatggaa aagactggta aaacgaagat
    18541 taaaggtgaa ttattcaaca ttggaattca aaataatcca gtatcggtca atgtaatcaa
    18601 tgagaactta attccaaaag gattctttac ccctgtgcct cccaaattgg ataaaaagca
    18661 attgaaggag gaactgaagc acggagatat tcctggtgct gaactcgtcc aaacaaaagg
    18721 tttgaggata agatgatgaa ggaggagaaa taatggaaca cgaaaacgta aaagacgctt
    18781 tgaaagctgc tatcgaaatc gcggaagcta aaggaataaa ggttgacggc aaaccagcaa
    18841 ctgtccatga cattcaaaat ttgacgaaag aacatcttta ttttatcgcc gacttgcttg
    18901 gtttgtcgga attgtattta gacaaataac cccacacgga aggagtggct agggtggttg
    18961 tattacaagt aatagtctgc gtaacattca tttggtcgtg cataccggtt tgtatatata
    19021 tcatgaagaa gcttcgccct gagtcttaca aattatacgc aatttacagc ataacagtag
    19081 ctcttgcatt tacattgttt gcaatttcta ggcttccgtt ttaatcgtgg gaatgaattt
    19141 ttaatgaact aaattatcta taaagcaaaa aaaggagaaa caacattgaa aaacaaacta
    19201 gcaaaaacaa cagcaatcat cggactagca ctaggtagcg gcgttatcgg ctacgcagca
    19261 agcaatgcgt ttcaagattt ggacacgatc aaagcaaatt tcaacacagt cctacaatac
    19321 ggtcaaacga aatcgcaacg tgtgtcagaa cttgaatcac agctatccaa caacactcgc
    19381 acacaggagc agctgaaagc cgaaattgag caaatcaaat cggacaagca gaaggaaatt
    19441 gaagccaagc aacgagaagt cgaacaaaag caacaggaga tcgctacaaa gcaacaggaa
    19501 gccgatagct tgcgccaaca actatccaca gtgcaaaacg acaaggagca gttagaacag
    19561 cgcgtgagcg agttacggca gtatacggat caaaaggtag gggagttggg gaaatgaaag
    19621 agttgactat ttatgaccca aatatttcat gggctaaaca cacaattaaa gtttctttta
    19681 tgatttgggg ttacaaagga tatgttactt acaaagtggg cggtaacact aagggtttat
    19741 cattaatagc tattgattca gatgatctat atgatgctaa tttcgaggat aacccagtta
    19801 atttccgtga ccttgatgaa gattggttct ctatggaact tactaacgat aaaggcgaca
    19861 gtacacttgt agaagatgaa ttcgacagac taggtgatta tattgtcggt gttgaaatta
    19921 ttgcgcacga accagagtag gagagtgaat acaaaatgat taaaagaatc actatatcag
    19981 ttgaagaaga tagtggatca acaatgcagc ataccgacaa tcgaaaaact tttttaacca
    20041 atagaaagga gaattttgat gcagattaag aaggcgacgg atatcgaaca aaccaaggga
    20101 acatatttga tctacggtgc tccaggaaaa ggtaaaactt caacggctaa atattttcca
    20161 gggaaaacac tgatccttga tattgatcgg acttcaaaag tccttagagg tgagaaaaat
    20221 gtcgatatcg tatatatcga caacgaagat acctggaacg actggggcaa cacgttggct
    20281 gatttaacta ccaattatgt aggtgtttat gacaacgtgg ttgtcgataa tgtcagcgaa
    20341 ttggaacggt gtattctgtc cagtttaggc gcagaaggaa aaaacaacgg cgttccttcg
    20401 caaggcgatt atcaatatat gcaatttaga atggtgaaca gcctacgcta tatgaaaaat
    20461 ttagacagca accttatctg gaccgcatgg gaagaaatcg atttgtggac ggattcggat
    20521 ggatcttctt acaacatcgc tttgccgcag atcaatcgaa agattcgaaa caatattttg
    20581 ggattatgtg acgttgttgg tcgattgatg gtaaaggaag acgatgaacg cggatttatt
    20641 ttacaagcca cagattcaac ctatgccaaa aatcaattgg ataatagatc tggctgtaag
    20701 caaagtgagc tgattttaga tggaattgta cgactaccag aatgatttag tcgatcgtgc
    20761 aagacaagcc tatgttgatg gttacaaggc accatgtatc gtatcaccgt gcggttctgg
    20821 aaaatcagtc atggttgcag agatcgctaa acgaaccaca cgaaaaggca acagagtgtt
    20881 gttcttggtc catcgtcgtg aattgattga tcagatcaaa gatacgtttc aaaagatggg
    20941 cgtagataat cagcttgtaa atttcggcat ggttcaaaca gtcgtacgac atcttaaaac
    21001 catcaagaaa ccacaactga tcatcactga cgaaaaccat cacgggttag cagcgtccta
    21061 cagaaaaatc tatgagtatt attcggacgt tccgcgatta ggttttaccg cgacacccat
    21121 ccggttaaac ggtagtgggt tgggggatgt gaacgacttg ctaattgaag gagtatcggc
    21181 taaatggttg attgagaatc atagattagc tccttatgaa tattatgcac ctaaattgat
    21241 cgatacagcc gaattaaaga aagcttcgac tggagatttt acaaagaaat caatggataa
    21301 ggcagtgaag aatactattt atggcgacgt gttgaaacat tataaaacgt tagcagaagg
    21361 tgaacaggca atagcatact gtcacagtat cgatgcaagt aaacacactg ctgaaatatt
    21421 caacgatgct ggttataaag caacacatat cgatgcaaaa actccaaaag atgaacgtgc
    21481 agatattatc gaagcgttca gaaatcatga aattaaaatc ctatgcaatg ttgatttgat
    21541 cggagaaggg tttgatgttc ctgattgttc gactgtaatt atgttgagac ctactcaatc
    21601 gttatcattg tacattcagc aatcgatgag ggggatgcgt taccgaccag ataaaacgtc
    21661 aatcatcatt gaccatgtgg gtaatgtgaa ccgttttgga ttgcctgata tggatcgtga
    21721 atggagttta gatacaaaaa agaaaacaaa aactgatagt gatttatcta tcgttcaatg
    21781 cgcgttttgt tttggtgctt acgaacggcc aaaaggcgat aatatttgtc cgtattgcgg
    21841 agagttgcag ccgattgaag aacgaaagtc agagttagaa atcgatgaat cggctgaatt
    21901 aatgaaagtc ggagaaacga aaattacttt gaattttgag aacaataaat attacaacat
    21961 gacggaagat gaagcagaaa gtatagagga cttatatgcc atagcaagag ctaaaggatt
    22021 taaacctggt tgggcttata tggctgctaa gaggaagggg tggttgtagg aatgggcggt
    22081 atttttggta aaaaagcaga agatgttcaa ggttcaataa taaatggcgt aacaataata
    22141 ggtgatactg gaaaaagaga tagttcaggc aatcaaattg taatcgctag aaataaaaat
    22201 aacgaagttt ttgaatcttc tctatctaat ataaaaagag gtgttgttaa cgggacaggc
    22261 gaagagagtg gctacgttaa tttaaaaaaa gctaatgaaa aataccatgt tgaaggaact
    22321 tacgttaagg ctttgtctgt cggtggaaca aaaggcgtta attgggataa acgaagaaat
    22381 aaatggaaag cacgattata tttcaaagga gaatatgtct tacaaaagga tttcaacacc
    22441 aaagaagaag caatccaagc acgacttgca gcagaagaaa aatatttcaa acctatctta
    22501 gaaaaatatg aaaataaaaa ggagaatgat taacatgaca ggatttaact tagacttttc
    22561 aaaagcgcaa caagggaacg aaatcaaaga cggtacgtac gaagtggtcg taaacaaagc
    22621 tgtagaaaat gcaactaaat caggcgcaga atttatcgat atcgatttga tcgttcgtaa
    22681 cgatgtggat caaccgttcc aaaataaaca cattttcgca aaaatctgga aagccaaagc
    22741 taccggcaaa tataacgaag gtatgatcat ggcaattgca caagcgctac agttggaaga
    22801 cggaaaatca tataacgggt ttgatgaatt gctggcggac tttgttttga aaaccgcctc
    22861 agtacgcgtg aaaactgaag agtcaaatgg atataaaaac gtcaatgtga agtcttggga
    22921 taaaacgaac acacggggcg taatgaatca ccaattcaaa aatggtgatg aaccatcctt
    22981 cggaccggaa cgttcaagag cgacaacggt tagaaatgac aatcttccat tttaattgag
    23041 gtgtaatcaa tgtatgaaaa aattccaaaa gagcttaaaa atctcaaaca atggtgtgtt
    23101 tataagctag tttgggatga aaagcggcag aagcacacga agatccctta taacgccaac
    23161 aacgggcata aagccaaatc caatgacgag agtacctggt ctgattttca gaccgctctc
    23221 gctgctattg atcactacgg aatgagtgga ctggggttct ttttcaaacc accttatttc
    23281 ggcattgata tcgataatgc tgaaggtgaa gttgagcgat ttaaatcagg tgatatagaa
    23341 gaaaatatta tctatgaatt tatcgaaagc atgagatcct atgctgagta ttctcaatca
    23401 ggtactggca tccacattat tgctcgcgga gaattgcccg gcggaagacg caggaaaggt
    23461 gacgtagaaa tgtaccagaa cggccgattc ttcgttatga ctggaaatgc cgcatcaaaa
    23521 tatttagaaa taactgagcc gaatccaaag gatatcaaac gcctatatga tcgctacgtt
    23581 ggagatgaaa aaatcatcca attcaaagaa gaaaatccgc tgatgaatac cgttgattta
    23641 ccggttgaag aaattatcaa acgtgctgaa tcgtcttccc aaggggcaag attcaaagtc
    23701 tttatgaacg gcggttggga agctttttat tcctcgcaat ccgaagcgga tatggcgttc
    23761 gccaacgact tggctttttg gaccggtaga gactttgaaa aaatggatga gattttcaga
    23821 gcgtctgcaa tgatccgtag caaatatgac caaaaaaggg gatcggcaac ttacggagaa
    23881 tctctactaa ataaggcaat tgctgataca aattccgtct acaaccccaa acggaaatct
    23941 gattttaaga tttttatcaa agaccaggaa cagccaaaag aggaaaaata ctattcgtac
    24001 gacgacaccg gcaacgcgga tcggtttact gatatctacg gaacgttagt caaatattcg
    24061 tacattgata aatcttggta ttactacgat gggaaagttt ggctacagga caataccggc
    24121 gaagttcgga aaatgatcga tacgacagta gacatcatgg gaaaagaacc gttaacgatc
    24181 cctgaaggcg cagacgatga aaccaaagaa gctttgatga aagcgaaaga aaaacacgtc
    24241 aagcgttctc gcagcaatgc cggaaaaaac gctatgatgg acgaattgaa acatcgacta
    24301 tccgtattgc cggaagagtt cgacaaagat aaaacgctgt tcaacacaca aagcggctat
    24361 ctgtctttgc atgacggtct tctacacgag catgagatag acaaaatgtt tacacgtgtt
    24421 tcaaatgtcg agtacacaga atcggtcgat tgtcctatgt gggaagaatt tattaatcag
    24481 atttttgaca atgatcaaga attaatcaga tatatccaga aatgtgtcgg atattccctg
    24541 accggatcta ccagagagca atgtatgttc atcctctacg gtcatgggtc aaatggaaag
    24601 tcggtatttt tggaaattat ttctgaattg atgggaaact atgcgatgac tatgcaggca
    24661 caaacgatca tggtcaagca aagccaatca tcagcaaaca gtgatattgc acgattgaaa
    24721 ggtgcgcggt tggtcacttc gtcagaaccg aatgaaggcg tccgactgga cgaaggtctg
    24781 gtcaaacaat tgactggtgg tgataaagtc acggctcggc acctttatgg aaaagaattc
    24841 gagttcgaac ctgaattcaa gttgtggctg gcaacgaacc acaagcccat catccgtggg
    24901 accgatgacg gcatctggcg acggttaaat ttaattccat tcactgtcca aatcccggat
    24961 cacaaaaagg ataaaaatct gaaatttaaa ttgcagacgg agttgcaagg gatccttaaa
    25021 tgggcaatcg atggttgcct gttgtggcag agagagggct tggagaaacc aaagtcggtt
    25081 gttgcagcga gtcaggatta tcgaaacgaa atggatcaaa taggtacatt tatcgaaacg
    25141 tgttgcgaaa caggtccagg actaaaaata tcaggcggag aattatacaa agtttatcgt
    25201 gaatgggcat cagataatgg cgagcatact ttcactaaca cgaagtttgg cagagagatt
    25261 tcaaagaaat atagcaaaga aaaagctggt ggatttatgg tttataaagg aatcacatta
    25321 aaaccaagaa aatacgataa cgttagagaa ctttttaaat aaatctggag ggttctggag
    25381 ggttgaga
//
LOCUS       DAFTHM010000031        23829 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFTHM010000031 DAFTHM010000000
VERSION     DAFTHM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.031"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(54..788)
                     /locus_tag="L7C88_001289"
     CDS             complement(54..788)
                     /locus_tag="L7C88_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBP9558132.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="L7C88_001290"
     CDS             1115..1525
                     /locus_tag="L7C88_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBP9558133.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="L7C88_001291"
     CDS             1518..2219
                     /locus_tag="L7C88_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBP9558134.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="L7C88_001292"
     CDS             2219..3805
                     /locus_tag="L7C88_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558135.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="L7C88_001293"
     CDS             3824..4045
                     /locus_tag="L7C88_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBP9558136.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="L7C88_001294"
     CDS             4042..4803
                     /locus_tag="L7C88_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBP9558137.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="L7C88_001295"
     CDS             5183..5692
                     /locus_tag="L7C88_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBP9558138.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="L7C88_001296"
     CDS             complement(5767..6306)
                     /locus_tag="L7C88_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBP9558139.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="L7C88_001297"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="L7C88_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBP9558140.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7319..8170
                     /locus_tag="L7C88_001298"
     CDS             7319..8170
                     /locus_tag="L7C88_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBP9558141.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8198..8833
                     /locus_tag="L7C88_001299"
     CDS             8198..8833
                     /locus_tag="L7C88_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBP9558142.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="L7C88_001300"
     CDS             8853..9626
                     /locus_tag="L7C88_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBP9558143.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="L7C88_001301"
     CDS             10034..10831
                     /locus_tag="L7C88_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBP9558144.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="L7C88_001302"
     CDS             10809..11222
                     /locus_tag="L7C88_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBP9558145.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="L7C88_001303"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="L7C88_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBP9558146.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="L7C88_001304"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="L7C88_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBP9558147.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /gene="maf"
                     /locus_tag="L7C88_001305"
     CDS             15999..16559
                     /gene="maf"
                     /locus_tag="L7C88_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBP9558148.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="L7C88_001306"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="L7C88_001306"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBP9558149.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="L7C88_001307"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="L7C88_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBP9558150.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="L7C88_001308"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="L7C88_001308"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBP9558151.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20261..20863
                     /gene="ruvA"
                     /locus_tag="L7C88_001309"
     CDS             20261..20863
                     /gene="ruvA"
                     /locus_tag="L7C88_001309"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBP9558152.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAIEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20876..21877
                     /gene="ruvB"
                     /locus_tag="L7C88_001310"
     CDS             20876..21877
                     /gene="ruvB"
                     /locus_tag="L7C88_001310"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBP9558153.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21906..22484
                     /locus_tag="L7C88_001311"
     CDS             21906..22484
                     /locus_tag="L7C88_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBP9558154.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22536..23018
                     /locus_tag="L7C88_001312"
     CDS             22536..23018
                     /locus_tag="L7C88_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBP9558155.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23135..23509
                     /locus_tag="L7C88_001313"
     CDS             23135..23509
                     /locus_tag="L7C88_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558156.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7782 a         4285 c         5114 g         6648 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgag
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcacccggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa
    20221 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    20281 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    20341 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta
    20401 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    20461 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    20521 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    20581 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    20641 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    20701 cacaaaagac gctacagctc tatctgaagc aatagaagct ctctcggctc ttggttacag
    20761 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    20821 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    20881 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    20941 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21001 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    21061 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    21121 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    21181 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    21241 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    21301 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    21361 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    21421 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    21481 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    21541 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    21601 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    21661 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    21721 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    21781 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    21841 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    21901 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    21961 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca
    22021 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    22081 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    22141 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    22201 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    22261 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    22321 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    22381 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    22441 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    22501 tggaaaagca ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    22561 tgggaaatat ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag
    22621 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    22681 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    22741 tggttgctcg gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    22801 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    22861 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    22921 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    22981 tttggattga tgaaaataaa ataacaaata atttgtaaag ttaacgcttt ctttttaagg
    23041 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    23101 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    23161 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    23221 tgacactgaa gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca
    23281 aaaagctgct actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag
    23341 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    23401 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    23461 aataacaatc ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga
    23521 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    23581 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc
    23641 ggttgattag ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta
    23701 gccggggagc tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt
    23761 ggtatgctta tataatagtc attagttgtg aatattttgt gacgaaagtt ttcgaaagtt
    23821 gttaagttt
//
LOCUS       DAFTHM010000032        23694 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFTHM010000032 DAFTHM010000000
VERSION     DAFTHM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.032"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(56..622)
                     /locus_tag="L7C88_001314"
     CDS             complement(56..622)
                     /locus_tag="L7C88_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBP9558157.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(650..2152)
                     /gene="eat(A)"
                     /locus_tag="L7C88_001315"
     CDS             complement(650..2152)
                     /gene="eat(A)"
                     /locus_tag="L7C88_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBP9558158.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(2410..3531)
                     /locus_tag="L7C88_001316"
     CDS             complement(2410..3531)
                     /locus_tag="L7C88_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBP9558159.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3657..4598
                     /locus_tag="L7C88_001317"
     CDS             3657..4598
                     /locus_tag="L7C88_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBP9558160.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(4748..5644)
                     /locus_tag="L7C88_001318"
     CDS             complement(4748..5644)
                     /locus_tag="L7C88_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBP9558161.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            5913..7253
                     /locus_tag="L7C88_001319"
     CDS             5913..7253
                     /locus_tag="L7C88_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9558162.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            7471..7914
                     /locus_tag="L7C88_001320"
     CDS             7471..7914
                     /locus_tag="L7C88_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBP9558163.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(8418..9836)
                     /gene="nhaC"
                     /locus_tag="L7C88_001321"
     CDS             complement(8418..9836)
                     /gene="nhaC"
                     /locus_tag="L7C88_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBP9558164.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(10239..11462)
                     /locus_tag="L7C88_001322"
     CDS             complement(10239..11462)
                     /locus_tag="L7C88_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBP9558165.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(11493..12332)
                     /locus_tag="L7C88_001323"
     CDS             complement(11493..12332)
                     /locus_tag="L7C88_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBP9558166.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(12349..13029)
                     /locus_tag="L7C88_001324"
     CDS             complement(12349..13029)
                     /locus_tag="L7C88_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9558167.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(13031..14104)
                     /locus_tag="L7C88_001325"
     CDS             complement(13031..14104)
                     /locus_tag="L7C88_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9558168.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(14160..14398)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(14441..14674)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(14751..15422)
                     /locus_tag="L7C88_001326"
     CDS             complement(14751..15422)
                     /locus_tag="L7C88_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBP9558169.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(15509..18187)
                     /gene="mgtA"
                     /locus_tag="L7C88_001327"
     CDS             complement(15509..18187)
                     /gene="mgtA"
                     /locus_tag="L7C88_001327"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBP9558170.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            18846..19283
                     /gene="ndk"
                     /locus_tag="L7C88_001328"
     CDS             18846..19283
                     /gene="ndk"
                     /locus_tag="L7C88_001328"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBP9558171.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(19305..20171)
                     /locus_tag="L7C88_001329"
     CDS             complement(19305..20171)
                     /locus_tag="L7C88_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBP9558172.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(20331..22424)
                     /locus_tag="L7C88_001330"
     CDS             complement(20331..22424)
                     /locus_tag="L7C88_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBP9558173.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(23173..>23694)
                     /locus_tag="L7C88_001331"
     CDS             complement(23173..>23694)
                     /locus_tag="L7C88_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558174.1"
                     /translation="QKETEKIVASKESVDNFKKEFSTYWWAEYKITANYEKGELDIYL
                     PKGKEENQFINIDDVLSAISLRQYQFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEK
                     VDKKVVADRLAEWKKTNEQVKKTTVSSQKNESTGTSPSDSGSGQTITGSEENQASIIT
                     NESSQGQYQSYGQ"
BASE COUNT         6791 a         4920 c         4179 g         7804 t
ORIGIN      
        1 tgctaagcaa aagcagtgcc ttgaaatatt ttatttaaat aacacaaaaa cataattact
       61 cataagaaac caattctgta ttatctacca tgaatgtaaa gaacccctca ttaggcatcg
      121 gatgaaaata agcattgatc actcttatca aggcattatg gcaaactaac agatagacat
      181 tttcttcgtc ttcgatgcat tctttcaata aaggaacgat ccgtgcatac acatctaaga
      241 ctgactcccc atttgggaat cgtacagcga acgctaaacg tgctttttga aagttctcat
      301 ctttgcttgg cagtccatca taatccccaa aatccatttc taccaatcgt tcatcaacgg
      361 tcagcggcaa gctgagacga tcagcaactg cttgtgctgt atctcttgct cgttgaagag
      421 gggaatggat gattttcgtg attggaacag gcaaatctac taccttttct gctagtttct
      481 gtgcctgcat ctgtcctttt tcagtcagcg gcacatctgc ccgtccgcaa actaatcctt
      541 gtgcgttcca agttgtttct ccgtgtctcg ttacataaag catgtgattc tctccttcgt
      601 tggcaaagtt ccccttaacc ataccttgtt gttcttgaga ttacaagggt tagattctct
      661 caagagaaat aatctcagta gatactttat ccaggaaggt ttgatcatgt tccactagta
      721 acatggcagg tttcacgttc aagatcagtt gttctaattg ttcttgattg aagacatcca
      781 aataattcaa tggttcatcc catgtatata gttcagctgg ctgtgataaa gatttagcca
      841 attccacttt tttccgttgg cccatactca tctgctcgat cttgttatga aaaacatctc
      901 tttccatccc aagctttcgg aggttgttca aaaatgcttg gtagtctact tggtttttct
      961 ctgcaaattc cgccaacgtt cctcgattgt cttcataatt ttggcttgca taactaatgc
     1021 tcagatgttt tggctggtat ttttctccta taaccttgcc gttgaatgcc cccagaagat
     1081 aatggataat ggatgacttt cctgcaccgt taggacctga aatcgccacc cgctgatgag
     1141 gctcgattgt aaaatgaatt ggctcgaata acagattttc ataccctaat tgaagatctt
     1201 ctacgcttaa aagtcgctta tggtgagacg cttggctatt catcgtcaaa gaatcgatat
     1261 attcgatatc ttttaatagt ttttctttct cgctgatctg ggtctccatc cgattcacga
     1321 ttgctttgga tcgtttcatc gtccgtgcag catcagcacc cactgctcct ttattcactc
     1381 gtctagattc agtatcgatg aatccgactt gtttctttgt tttatctcct tctcgggaac
     1441 gagaccattc ggctttttca gctgctgttt tctttagcct actgacttct tttttcaatt
     1501 tttcattttg agccatttca aattcatcac gaagtttttt ctgttcttca tagatagaga
     1561 aattcccttg ataaagttcc agttgacttt tttcgattgc taaaacatgg tccactactt
     1621 catcgataaa tccccggtca tggctgacca cgatgaagcc ttgttttttc tttttcaaat
     1681 aagccgctac ttgttttcta ccagagatat ccaaatgatt cgttggttca tcgattaacg
     1741 ggaaatgagt gtcatccaca aataaaagtg ccagtaggac ttttgtcttc tctccccccg
     1801 atagtgtgct gaattctctc cataagattt caggatctgt ttgcatcaat tggagctctc
     1861 tttcgatttc ccatatctca aaatccgtaa tatcatttaa cacgtaatag gttaaacgtt
     1921 ctttatcttt tgtctgttgc gggaaatagg caaattcttg ctgatggatt acttgccctt
     1981 gataaggtag tttgttttgt agaatattca gtaaagttgt ctttcctcga ccgtttcgtc
     2041 cgataagtcc tagtttccat tgtgtgtcaa aatttagatt tgcttgttca aataataatg
     2101 tgccttggct gtcgtagccg aatgtcagat tttttatttc gattttagac attttccatc
     2161 acctcgtaaa aaaagaccag tcctattttc agaactggct aaagaggatg caagggttgg
     2221 atacacacaa aaagacccat acatcgaaaa aaccaagcca atcccgaaaa tctgcacact
     2281 gcttccttgt ctccacaagg tacagtctga atgcagcttt catcaatcga cttaattttt
     2341 caatgcacgg atccctcact ttgtcctata tttgaaatta cgatagcata aagaaaatga
     2401 ttttgtcaac tacttcggga ggatggtgaa aaatctgcta agtgtctgtc ctaagatttt
     2461 tgttttttct aatgtttgcc tgtgttccat tgcttcttct aaacctattg gacccaaatg
     2521 aatacttaag acaattggga gaaaatcaga aagtccttct agctcttggt ctctacttcc
     2581 gcaaatagcg attattggtt ttcgatattt ttttgcaagc actgctacac cgtatggaac
     2641 ttttccgtgg atcgtttgct gatcgatccg cccttctcct gtaatgatga catctgcttg
     2701 ttcgatcttt ttttccaatc cagtgatttg gctgactaaa tcgaaaccag aaaccatctt
     2761 cgctcccaac aaaaaaaggg ctccaccaat accgcctgct gctccacttc ctggaatatc
     2821 atctaaatcc acctcccaga aatcttttat ttgctgagca atctttcctg cttgtttatc
     2881 taagaaagct agcgtcgtat ctattcctcc tttttgtctt ccaaattgcc aagcagctcc
     2941 ttgttgacct gtatatggat tggtaacatc tgcagcgata atcaatttta ctttagaaac
     3001 aagaacgttt cttcgatcaa aatgaagttt tttagtagat aataaaggat ttccttctgt
     3061 gtacccttct aaagaagcac ccaaggattg gagtaatcct agaccaccat cgctacaccc
     3121 gcttcctcct aaagtgacaa taatttgttc tacttcttga agcagtgcat ctttaataag
     3181 ttctcctaag gcataactgg aagcaagtcg gatagtttga tccgttggtt tatcaagtag
     3241 atctaacccc aatgcttgtg cagattcgat gactgcggtg ttttttcctt gccaagttgt
     3301 caataaatag ctgatttttc gctgacggaa taagagatcc atcccatcaa tggtacgcca
     3361 tgttcccctg agcgcgtaat agattgcttc tgcagtattt tctccgccat ctgcaatcgg
     3421 cacattgatt tttcttcctt tacgatcttc ccagccattt agaactgcct gatttagttc
     3481 aaatgaagaa gcacttcctt taaatgaatc aattgccgcc aaaatatcca tctgtatccc
     3541 tcactttctt cttaagtaag acactttttt tcattttttt caaacaaaac aatgctattt
     3601 tcttccattt ttctatatac taaaagggaa ctcattgaat aaaggagaga aaaaacatga
     3661 aaatcgcaat agctggggcc ggagcaatgg gcagccgaat cggattgatg ctacatcaaa
     3721 gcggaaatga ggtcctcttg atcgatcgtt ggcctgctca cattgaagcc attcgtacaa
     3781 atgggttgat tgctgacttt aacggtaaag aagtggtcgc aaaactgcca atctattcac
     3841 cagaagaaat catcgaaagc aacgaacacg tggacttgat cgtagcatta acaaaagcca
     3901 atcaattaga tgatatgttt tgttcgatcc aatccattat tactgacaat acttatgttt
     3961 tgtgtttact aaatggatta ggtcatgaag atgtactgga aaaatatgtg ccaaagaaaa
     4021 atatcttatt tgggatcacg atgtggacag ctggtctagc tggtcccgga aaagtcacat
     4081 tgttaggtga tggagaaatc gaactagaga acttggaacc agaaggcgaa gcatttacaa
     4141 aaaaagttgt agaagtcttt caagaagcaa atttaaatcc gatctatagc cataacgttc
     4201 gttattccat ttggcgaaaa gcttgtgtaa atggaacatt gaatggttta tgcacgattt
     4261 tggattgtaa tattgctgaa ctaggcgcgc aaaaagcggc agagagcatg gttcgaacaa
     4321 tcgtatctga atttgcttct atcgcagcaa aagaaggaat catactagat caagaagaag
     4381 tgtaccaaca tattgcttct acttatgatc ctgacaacat cgggttgcat tacccatcta
     4441 tgtaccaaga cctgatcaaa aaccatcgtt tgactgaaat cgactacatc aatggtgcca
     4501 tttggcgaaa aggacaaaaa tatgatattg ctacaccata ttgtgccttt ttgacccaat
     4561 tagtccatgc aaaagaagga atccttggcg cagaataaaa ggctctctga tgagaatcag
     4621 ctgaatcagc agctggttct ctttttttaa gcccaataaa agatcaaaaa gaaaacacaa
     4681 ctctcatgat gccataagaa ttgtgcttgt ttgtttcagt acataatctc ttcaaaatgt
     4741 aggtttttta tttgttttca acagaggaga ggtcatattc gtattgctca taaatagtgg
     4801 aatcgttagt gataaatcgt tttgcccaat tttctgcatc ataaaattcc aatagctctg
     4861 ataggattgg cttaaatggt gtatgcagaa attccggtaa ttcatctaaa tcacgttctc
     4921 gaagcaaaaa aatattttca ggacgataaa aatgataatg agcaatcgct tgattatccg
     4981 tcactagttt cttttgaaaa tacatggatt caaatgtccg caaagtcact ccttgctgac
     5041 cctcccgcaa cagttccaga atcccgcgcg attcccctgt ttttttcagg tactcttcat
     5101 aagtaagata tccaggttgt tcattccctc gatgtggaag aatgaaatag ttggtcgtaa
     5161 catctctttt tataaattcc tgcttatagc tttctgctcg ttcttttctc ccattattcg
     5221 ttgcaccaaa aaatagatcc gtctttggtt cgctagaaga aaaattcata tgtttcgaat
     5281 aaaatgaact attatgtttc agcccaagtt cttttgcttc caaaaaatca aaatgataaa
     5341 tctcatcgat tgccggttca tcttgtgcct gcttcagcat cgcctcgtgt tctgctttga
     5401 agtgattcca aaaaaataac acaatttttg cattggtaaa tgggcgcacg cgtcgagcca
     5461 tctccatatc aaatccataa tctaaaaaaa cgatcagctg ataatttgcc aactgttgtc
     5521 tagctgattt aatgaattcc gactgtagta aatcttttcc ggaccaaaca tctaaagagc
     5581 ggatggaagg caaaaaataa agtgatttat tttttgcaac tagcagtacg tcatttttgt
     5641 tcatcttttc cgcctcactt tctctgtcac tttttcctat gatagcctgt ttaaatagta
     5701 aaaagccagt aaaacgtttc ctatatttgt atgaaaattt aacatttgta tgaaaatatg
     5761 atgaaataaa tcattcttct attaaaattc gcctaaaagt tttctgaata gttgtaattg
     5821 tctgaaaatt tgttatcatt agtcattgtt aaatattgct atttattctt aatataaatt
     5881 ttgattgtga atttaaaaga aagaggtcat ttatggaaga taaaaaattg aaaaaacaac
     5941 ttagctccag acatatcacc atgttagctt taggtggagc aatcggtgca ggtctattta
     6001 aaggaagtgg cgaagcgatt gggatcgccg gcccttctgt attgattgct tttttgattg
     6061 gtgggctgat tttatatatc gtgatgaaag gtctgggaaa aatcgtttta agcggtggcg
     6121 acacgcatca cggattatct ggtttgatac gcccttatct aggtgctcat tctgctgatt
     6181 ttactgattg ggtctactgg tctatgtgga ttatcaatat catcgctgaa gctgttgcag
     6241 ctgcttcctt tttgcagttg tggttcccgc acattccagc ctgggtattt gtttttatgt
     6301 tggctgtttt aactacgatc atcaatcttt attcggtacg gttattcgca gaaacagaat
     6361 attggctggc ttttgctaaa atcagtgtca ttatcttact gatcattttt gctacttatc
     6421 ttgtcggtca gcaaatgttg ggcacaggcg ttttccctac ccttcagcaa ttgactgacc
     6481 atggtgggtt tactcctcat ggtatgaagg gaatcatcag ttctttgctt gtagttatct
     6541 attcttacgg cggttctgaa ctgattgcta tcacggtaag cgaagcagat gatcctaaac
     6601 gtgcgattcc taaagcaatc aaaggtgtca tgggaagaat catttccttt tacatcattc
     6661 ctttgttttt gcttttgatt ctttttcctt ggaatacttt agcaggcacg aatgtcagtc
     6721 cttttgtgat ggtatttgaa aaaatgaata tcccatttgc agcggatatc gtcaattttg
     6781 tgattgtcct tgctttgttc tcatctatca attcgggtgt gtatgcatct tcaagaattt
     6841 tgttcttccg tttgaaggat cgaaaaggtt cctctagaaa actagctgtt ttaaacaagc
     6901 atcaagtacc gcaacgtgct gttttatttt gtaccagtgt tctttatctt ggtgtagctc
     6961 tttcttattt tgtcggtgac aaattatttg gctatctggc aggttccctt tcgtatacag
     7021 tattattgat ctggatcatt atcagtgcgg catcctttgt actggcacta agaaaaggaa
     7081 cattatggga taaaggaatc agcttttttg cattagctgt cttaggattg attttccttg
     7141 gtatcctgtt cacgaactcc attggggtaa ctgtattgac tggcctgctt tacctgttca
     7201 tttatttcag ttatcaaaaa aagaatgatg cgttcgtatt gacgaatgaa tgaaatcgat
     7261 agaaaatttt attttattta tgtggaatag atggagctat tgaagaaagg agttgtgaca
     7321 aaagtcttgt tgcaactcct ttttccgaat aaacagtctc atgacctctt ggtaaacggt
     7381 gttcaaaaac cctctgtgca aaataattga ttgttctcca tgctcatgac atgatagaag
     7441 aaaggaatga aaaaaaggag tttgttttaa atgaaaaagt attggaagtt tttgttgatg
     7501 atcggtgttt caacggtagt tatgtttggt atgatgtact tgaatgtcta tgcgctcgat
     7561 catatcttct tcagtcgtac acgagtattc atggcgttga tgatgggtgc agtcatggca
     7621 gtcatcatgc tgttgttcat gtggaaaatg tatgaaaaca aaaagataaa tgttatgatc
     7681 ttagccgcta gtcttcttgt ttttgccggt tccttgttta tggtacgaag ccaaactact
     7741 gtcaacgaca cagcttggat gaaggccatg attcctcatc attctatcgc tatcctggca
     7801 agtaaacgag ctgatttaaa agatcctgaa gtaaaaaaat tagcggaaga aatcattcag
     7861 gcacaagaag aagagatcga caaaatgaaa aaaatgatca aagaaatgga atgaccatta
     7921 tccgtccaaa taaaaaaaga ggatgttcca gaagttatca gcttcaagaa ataagaagaa
     7981 gctacttctg gaacgccgtg aataaggggt tgtgaaaaag ctgccctgca tcaagtaata
     8041 agaacagcca aacaaaaata gcttctccta tttttcgttt ggttaggctt attaccgcag
     8101 atgcaagctt ttgaacaccg tttattaaga ggttgtaaaa tcagcgttct gacctgagta
     8161 ttagagagac aaatggaaaa atagttcctc atattttgcc attttttgag ctaataccga
     8221 gggtcagctg attgaacacc gtttatcgag aggttgtgaa aaagtcgctt agtttcgcgt
     8281 attaagaaaa attttgtgaa atggctttcc acatttttgt ataaatttgg cttaataccg
     8341 agaaactggc ttttgaatac cgtttattcg taaaagggat tgtgacaaaa gtcttgtcac
     8401 aatccctttt tatgttttta ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt
     8461 ttcacaaatt tttttgagat tccccaacct gtgaaggcac tgaccatcga aaacacagga
     8521 gaaagcaaac tgaaaaatac gaatggcaag taagtgagtg taggaatacc aaatgtactt
     8581 gctacgaaac ttccggcaat tccccaaggc actaagtagt tgattactgt tccaccatct
     8641 tctagcgttc tacctaatac agttggatca aatcctgctt tttcataagt ttctttaaat
     8701 gcattaccag gcagaataac agataggaat tgttcaccaa taaaaatatt tactccgata
     8761 cttgtcatca atgttgtaaa aatcaaattt ggtgtgttcg tcatctttct tgatactcgt
     8821 tccatcacgg ttgagatcaa gccaaattcg atcaacaatc cacctaatga caaagttaga
     8881 ataatcaatg acacagtagg catcatactt tcgattcctc cgcggctaag cagtgaatcg
     8941 atttgttggt ttccagtatt tgaaacaaac cctgattcga tgaccccagc caacttcgtt
     9001 aaggaagttt gtgggttttg aataaaaatc attcctactg ctacagcgat attcaacaaa
     9061 atcgttaaaa ttgccggcac ctttttccat gcacacagta acattaaaaa taaaggaatc
     9121 agtgaccaga ttgaaatagt aaagtttgct tctagaacat cagtcacttc acgaatagat
     9181 gaaagacttg cggctttact tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca
     9241 aatgccggga cagttgacca catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca
     9301 atagctgctg ctagatttgt tgattcggat aatggagaca tcttatctcc aaaaacggca
     9361 cctgaaacaa tagctccaac aaccagcgct ggatttaagc ctagtgttgt cccaataccg
     9421 aaaaatgcaa tcccaatcgt tgacataaca gtaaaggcac tccctacagc gctacctacg
     9481 attgcacaca caacaaatac agaagggaca aaccactgga cactgatcaa tttgaaccca
     9541 atgaccatta gagttggaat gatccctgct tgtatccata cagcaatcaa tgaaccgact
     9601 aaaataaaaa taaagattgg gatgattcct ggtttgatgc cattgatgat tccttcgtgc
     9661 agccaatctg tcgggtatct ttttatcact gcatacaaca tgaccattcc gatcgctgct
     9721 aagatcgtga tattaggtga gacctttaat ccgacaacgc caatcgcaat gcctaaaaca
     9781 ataaccatta atacaagtgt tgcttctaaa aaacttggtg ttcctttttt tcccatgata
     9841 atctctcctt ttttagttgt tcttatgttc taaaaaagtt aagatatcgg attactccgc
     9901 cgcaattcat ccgcgattcc tcctttataa aaataaaaag acctgtttta aactaaggac
     9961 gaatgactcc gcggtaccac cttaattaaa aacagatctg tttttcactt tcaaactttt
    10021 attcaaatgt atggactttc catgtaattc gtcaattagg cttgatcggt tcacagcgac
    10081 caccgacttt ctgaacaaaa cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag
    10141 tttaccttcc ataagatcat ttgtcaatga aaaagaaaat attttttcat ttttctgaaa
    10201 attattttta taactttcac acacaagttt attttttact agaaagtagc gccctcttgt
    10261 ttttttcttg ctactatttc ttgatgttct tgcttgattc tttctaatag ctttggctct
    10321 ttcaacagat caagagctgt attggcgagt agttctgctg caatcgcaat agaagcaagg
    10381 cctttgtcac ttttagcagc agctttgaat tcttctgtgt gtccggcaat atatgtctca
    10441 gagattgcta ccgtaggctg gattgttggt atgacttggc tgacatttcc tacatcagaa
    10501 gaaccgagac ttgttctttg ttccgtttct atttcttcat ctggaacacc tgcttctttt
    10561 gcatgctgga agaataagtc atcaaaagaa ggagtaacga tgacatcatc aactgcattt
    10621 tggaacaatc caaactcaaa agtcgtgccc gtacttatcg cagcacctcg tacgatattt
    10681 tccacttttt catatacttt atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt
    10741 ccagcagcgt aatctggaat gacgttggca gctactcctc cgtctgtaat gatcccatgg
    10801 atattgacat cttttggcaa ttgcaagcgt agagcgttga ttccattaaa cacttggatc
    10861 aatgcttcca aagcatttac tcctttttca ggtgctgctg ctgcatggga agcgacaccg
    10921 taaaatttga tgtcgactgg atcattcgct aaagattctg tcgttttccc ataacgaaaa
    10981 gctggatgga cgcataacgc tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg
    11041 cctttagctg atccgttctc gcccccttct tcccctgggg tgccatatac acggatttct
    11101 ccaccagttt catcaatgaa ttgcttcact atgctggcgg ctaatacgga gtaagtacca
    11161 aacaaattat gcccgcatgc atgaccaata cctggtaaag catcgaattc tgccaaaaag
    11221 gcaattgtgg gaccgggttt attggaaata taacgtgcat caaaggctgt tcggtgtcca
    11281 gctacttctt tttctaccca aaacctttct ttttctaatt gtttaatcaa cgctgctgag
    11341 gaataaaact catagttact tacttcagga tgttcgtgga tatctagagc aagtgcttga
    11401 tattctggta aacgatattg gattagatcc ttcaattggt ttgttgagat tgttgttgtc
    11461 ataaaaaatt cctcctatgc tagtcatttt tcttattttc tcccgaatgt ttcccatgca
    11521 ggcacgcttg atccttttga tgttttctcg attactttga ctgtgtcttc tgtttgataa
    11581 gcgtctacta ttttttgata cgttttattg ttttcatctt cttttcttgc aacgatgata
    11641 ttcacataag gacgtgcatg gtcatccact ggttctaaga agatggcatc agaagcagga
    11701 ttaaatccag catctacagc tacaccgcta ttgatcactg aaatgtctac atctgacaaa
    11761 gcacgtgctg tttgggaagc atctaattca gaaatgtcta gattttttct attctcggta
    11821 atatcagaaa cagtgggcgc ttgtcctttt gccttatcca ctttgatcaa tccagcagtt
    11881 tgcaataaca gaagagctct gccgccattt gtaacatcat tagggattgc tacttttgct
    11941 ccgtctttga tatcagctac atccttcaaa gtgttagaat aaattcccag cggtgcattg
    12001 acagtatttc cgatcgatac taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag
    12061 aattgatgtt ggaaagaatt caaatcaatc gatccatctg ctaaagccac atttggttga
    12121 ttgtaatctg taaatttcac gtattccaaa ttaatgttct cctttttcaa acggtctttc
    12181 acgttgtccc atacatctgt atcttctcca ataatcccta gttttacgat agtttctttt
    12241 ttgtcagttg tatctgcttt tccttggcta caccctgcca accaaataat tgctacaaat
    12301 gtaatgacta caaaacgaat aatttttttc attttttctc ctccactttc aatgtgtaat
    12361 ttttttaatc agttgattac tgataaattg acttaaaaaa actaagatta gaatcaataa
    12421 tgtagccaca atcgttacat ctgtttggaa tcgattatac cctctcgata tagcaagatt
    12481 ccctaatccg cctgcaccta ctgctccagc catggtagtc agtccgatca cgttgatgat
    12541 agtcaacgcc gagacccgaa tgataccagg caaaccttct aacaaataca cacgtaaaat
    12601 gataccgatt ggactggttc ccatcgcttc tgccgcttcg atcaccccag gatcaacttc
    12661 tagcagtgcg ttctcgattt gacgagcaaa aaacggaaca actccaaaaa tcaatggcac
    12721 taaagctgct ttcgcaccaa tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag
    12781 agaaagcaag ataatgaaag ggatggaacg aatgatattg atcagcttat caagtatttc
    12841 aaatagcaga cggttagcta gtaatccatt agggcgtgtc actactaacg tcacacctaa
    12901 gatgattcca atcatcccgc caatgaatgc tgtccaaaaa gacatatata gtgtttgctt
    12961 cgtcgcttcg acaaattcat ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa
    13021 atcagtcatt ttatcttcct ccttcgatca ctttgatacg actatctaaa tcgttttttt
    13081 gtaaaatatt tatttttaca ccagatttga tcaaataatc caatgctttt ttccgctgtt
    13141 tggtttctcc agctaaagta acgatcaaac tccctaacgg cgtttcttgt aataactcta
    13201 cattgccata taaaatattc gctgttactt gatatttgct gtacagatga gcgattagag
    13261 gttcgttcgt ctgatttcca atataactta attccaccag ccatttattg gcgatctgat
    13321 cggcaaaagc agaatgggca atgatcgttt ctaatgcttg gtcaagatga gtagctgttc
    13381 gaataaaatc tttggtcaat tcttcttcag gattgctgaa gatctggatg ctgctacctt
    13441 tttcaacgat tcttccatct tccataaccg ctaccttgtt gcagatttct ttgacaactt
    13501 gcatctcatg agtgatcagg acgattgtta aacctaactg gcgattcaat ttttttaaca
    13561 atgcaaggat ctgaagggtc gttttcggat caagtgcact ggttgcttca tcacataata
    13621 ataccttagg ttcattcgcc aaagctcgtg cgattgctac tcgttgtttt tgtccccccg
    13681 acagttgttt aggataagca gatgcttttt cttccaaacc gacaagttcc agtagttcat
    13741 tcactttttg acgacgttcc tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt
    13801 tgtcaaaaat agttcggctt tccattagat tgaaatgctg aaagatcata ccgatggcct
    13861 ttctttcttt tcgcaattct ttgggagaga gctgactcag attcgtctga ttgacaatga
    13921 cttctcctgc tgttggtttc tgcagcaaat tcatcacacg aactaacgta cttttccctg
    13981 cacctgagta accgacgatt ccataaacat cgcctttttc aatcgttaaa tctacagaat
    14041 ctactgcctg tatctctttt tctttttgtt tgaaacatac agaaacatct cgcaattcaa
    14101 tcattaaaat tcctccttat ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc
    14161 ttgaggacgc ttttttgcgt gttaccacct catgttcaag ctgtgttcac acacaactcc
    14221 tcttcaagta cgatcatact ctagcaagat atcggtcgca gccgtcatcg ccttacatct
    14281 atgctcggga tgaattgctc gatggccatt ttccaatagt cgttccttgc ttcttctcag
    14341 ctaccgaagc tctctgtcaa aggttcttct atcgtactta ccatttcaat gcaaataata
    14401 ttcaaaaaaa aagtcctttt actaacataa actatgtcag taaaaggacg acgtatcgcg
    14461 gtaccacctt ttttcggaag tttccttccc tcaagcccaa catctcaaaa agagagattg
    14521 gcgttcgttt taacggtcga acagttccga atttgcctac ttatcgacaa attattctcc
    14581 aaggccattt tcagcttttc ttacttgact cttctcacca gccagagcct ctctgcaaag
    14641 tttccaaact tactttcctt ttcaacgaaa tcgatatttt gttgttggga ttaatctaca
    14701 tgaggaaaac tgaaaagtca agtacgaaat tcaaattatt ttttctatat ttatttttct
    14761 gtttttttat ttaacatttc aataacagtt cgaagatctt ttccttccgc aagaagtttc
    14821 aatttttcct tttcttcgac ggtataattt cggacaaaac tggaatcagg tatcaaaaca
    14881 acgcctaatc ctgctcgtga agcagctgtt gctcctacta aagaatcttc cactgcaaag
    14941 gctgaactag cttctaatcc tgttcgttcc aaagctgtca gataaggaat cggtgaaggc
    15001 ttgttctccg acacttcgtc tccgaatgta aacgtgtcca agtaatcagc taatttaaag
    15061 tgatccaaga tatctgttgc tcttttcgta acagtggtcg tagcaatgcc tagtttcata
    15121 tgacgttctt ttaagtctgc caatatttct tttgcatatg gttttaagtg gatggctccg
    15181 cttgtcagct gttgataaaa atattcttca cgcttcgctc ggacttcctg tactttttca
    15241 gggctacctg ctgctttcac taaaatatca aaactttgtt tccagttttt tccgccccaa
    15301 gcgtcaacga tttcttttgg gatatggata tcaaattgct gaaatcccca aagccagcca
    15361 tcacgatacg ttttttctgt gtcaactaac aaaccatcta aatcaaatat tgcacctttc
    15421 atctatacat taatcctttc caaaacaata cacatagttt agcacgactg gtccaaaaag
    15481 aacagaagca aagaaccagc cttctcgttt ataagagttc ttggaatcga cggatataga
    15541 ttttcttcac agctgtcaca agcgccagat aagcgatgac tgtagcaaat aaccataacc
    15601 agtaattgcc aggaagtggc atcaagccta attcagcacc aaaacttgta aaaggaagga
    15661 cagaaccgac aataattcct aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt
    15721 ggataaatgg tactttcggt gtacgcagtg catggagcac taaggtttgt gtccatagtg
    15781 attcgacaaa ccatcctgca tggaataatg cgatgaaaat cactcgctgt gaactatcca
    15841 atgtatggaa acttccgccc actacagcag gacaaataac aaaatacatc aacaagtaag
    15901 tagtaatatc aaatatcgaa cttgttggac caaagtaaac catgaattcc ccaatactag
    15961 atgcattcca tttttttggc tcgtccaaat attctttatc catccgatcc catggcaagg
    16021 aaatgcagga aacatcatag atcagattca aaaacaaaag ttgtaaaggc agcattggta
    16081 aaaatggcag gaacgtactt gcaatcagca cggaaaacat attgccaaaa ttagaacttg
    16141 ctgtagcctt gatatatttc atgatattcc caaaagtttc tcgtccagaa agaaggcctc
    16201 tttccaaaat cgtcaaatct ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat
    16261 ccacagctgt atctacagaa ataccgatat cagccacttt cattgcagga gcgtcattga
    16321 taccatctcc taaaaatccg acagtatgac catttttacg taaagctgtc gtcaaacgtg
    16381 ctttttgctg aggattcaat tttacgaata cttcatggtc ttcagctact tgtgctaatt
    16441 catgatcact catttccgag attttctcac cggtaaccaa ttcattgatc tctagaccta
    16501 cttgacggca cactgaacgt gtaactaatt cgttgtcccc agtcagaact tttacagcta
    16561 caccatgttc tttcagagct ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga
    16621 aagcaagata accaatcaaa accatgtctg actcatcttt gactgaaaat tctccaacga
    16681 cgcttggatt ggtcttttgt gcgacaccaa tcactcgtaa gccatcttca ttaagtgact
    16741 gtacttttgc aagtacggct tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa
    16801 gatcaataaa tttagaaatg ttcagcattt cttcaatcgc gccttttgtg atcatttgtg
    16861 ttttaccagc tggatcagca accacaacac tcatacgacg acgttcaaaa tcaaaaggaa
    16921 tttcatccac tttttgataa ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa
    16981 tgatagccac atctaacaaa tttttcagcc ctgtttgata gtagctattt agatacgcat
    17041 ggcgcaaaac acgatcatct tcatttcctt cacaatccat atgatattca agaatgattt
    17101 tatcttgtgt caatgtcccc gttttatccg tacataacac atcgattgca ccaaagttct
    17161 ggatggcatt caaatttttg atcactgttc cttttttggc catcacactt gctcctttga
    17221 ccaaattcgt cgtaacgatc attggaagca tttcaggtgt tagaccaact gctacagata
    17281 gtccaaaaag aaaagcttct agccaatccc cttttgtaag cccattgatg acgataactg
    17341 ctggagccat caatgacata aatttgatca gtagcatgga tgttttatgg atgcctaatt
    17401 caaagcttga ttgaattggt ttttcagata gcgtttctgc tacatgacca aatagtgttt
    17461 catttccaac agaaacaatg attccttccg cacttccact gatgacatta cttcccataa
    17521 agacaagatt ttcgtaactt gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct
    17581 tttctactgg atagctttcc cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg
    17641 acaataaacg catatccgct ggtatcatat cccctgctga aagccgaaca agatctccac
    17701 agacgatttc ttccatagga atctctgtgt actttccatt acgttttaca gctgccgtta
    17761 ctttcacaag tgatttcagt ttttcagccg cttgattgga acgtacggac tgaatcaacg
    17821 tcattgtccc gctgacgata accatagtga agataatggc tacaccgaaa agatctttat
    17881 ctccaggagc tgctaataca tattccgtga tgaatgaaat aattcctaat gcgatcaaca
    17941 ctaatgtaaa tggcgtgatg tatgctttca atatttctac aatgaatggt gtttttttgc
    18001 catatgaaat cgcattttca ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca
    18061 atccatttgc tgatgcatgg aatagttcaa ataattcttg tttcgttttt ccagcaaaag
    18121 ctgcatagat tttttgtgta tctttctttt tttccatctc aatctctcct ttgtgtccaa
    18181 aagacagctg ttctcgctgc ttttggtctt tagctattca tcggatcgat agagaaaaaa
    18241 ctgaaagggg ctgagaacag atagataata gccctggcct ttcctctaga tccttgtttt
    18301 tcgaatgact gtcatccatt tgttctcatc tcctttacta agtaatttta attcatgact
    18361 tccaatcatt tttcgaatag ttatttttcc aattagacca cctccttttt atttttcacc
    18421 gatggggatt tgcggcaaca aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa
    18481 agcatattaa aaaaagcttc tcagatctca tcgttgagtt ttgacactgt acaacgtaaa
    18541 aagcagatac ctgcttttag ctaccttatg aaaagcctta tctcgacaat tcctgttcta
    18601 cccattggcg tctctcgacg tttttgggca gtagcctatg tttgtatagg agcctcacct
    18661 aacaaatctt attcggtttt ccttcgttaa tataacaact aaaaaagagg atgtcaaatc
    18721 aattttccat gtttttcata ctttttttaa aatacacacg ttatattcct gtctcacgcg
    18781 gttttatttg tctcattttc cacctcccgc tataatagaa atatagtagg aaacgaggtg
    18841 ctgttatgga aagaacactt gttattatca agccagacgg cgtgagacgc catttagtcg
    18901 gaagcatcat ccaacgtttt gaagcaaagg gactggccat tgctgaaatg aagtttgaaa
    18961 ctatgactcc tgaattagca aaagaacatt atcagcactt gactgagcgc agtttttttg
    19021 atgaactgat cgattacatg acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg
    19081 aagtgatcga tatcgtccgt aagatggttg gagcaacaaa agctgccgat gctgttccag
    19141 gtacgatccg aggagactac gcgctgccgg ggactgaaaa catcattcac gcttctgatt
    19201 cccgtgatgc tgcggtaaaa gagatcgccc gctttttccc gccattcgat ataaacaaac
    19261 cgtctgaaaa agcggcgaag tgatacaaat tctaaactgc tggtctagtt gctgggttca
    19321 gcaatggcca gcagtttttt ctctaaggac ctccgttgat tctttcctaa catatattcg
    19381 agcactgtga agaattcttg gtagtctttc gtcttttctt cccctaaagc agcagaaatc
    19441 aatctttgat aataatctgc catcaatgtt tcatagatca ctgtacttct ttctttatgt
    19501 gctaagctcc gtttcatatc ttcattcaca ctacgtgcct ttttcaaccg accattttct
    19561 atataaaacg aagtcaggtt cattaaaaaa gtaaagagat actgctcatg attgttcaac
    19621 tgtgctaatc gtcgcattct ttttttgatt ttcaaataat tgttctcaat gaaccgatca
    19681 ctgaatatcc aaggaaaatc agctagaata gatagttcaa attgaccata gtctggtatc
    19741 tgcatcaagt attcttcaat gattcggcat tcataacgta aaaattcaaa ttctgtctca
    19801 gatacttctg ttttttcgac catgtgaaga ttcaaaacca aataatacag atcttctgtt
    19861 ttcttaaaat gcctacggtt attgctgatc tctttataag gatcaaagct gtcttcttgt
    19921 acccgatcta gcattcgtct ttttttcttt aactttattg gttcatccag ctggtttcgc
    19981 atccattcat attctgcaag tgtcatgttc attcgctcta aaaatgatct caatgttaca
    20041 aatgacattt ttttcactga atttgtctca atcccgacta gagaagtctt aaaacagatt
    20101 ccttccgcta attgggactg tgtcaacttc ttgttgactc gaagtttctt gatcaattca
    20161 ccatcataca taatagttct cctttttaat ttaaattttt ccacattcaa taaatagata
    20221 cgttaaaaag gaaaaataca cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca
    20281 accttcaagc attagaatgt tgtctaacta ctgaaggttg gtttgattgt ttattgatta
    20341 tttttttgct gttcaacgtc tgttcttgtt actggatata agttggttgt tgttttatta
    20401 ccattttttg aaaagacact tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta
    20461 cgttccgctt catttttata gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc
    20521 acataaaacc gcaagagatt ttcctgattc agcttatctg aaagacttaa cgcagtcttg
    20581 actttttcct gatctttgga gatttcctca tcgattcctg ctgctttcgt atcgatgatt
    20641 tctcctgtct gattattgta agcttttcct cctaggacgg tgtatttggg tgtcacaaag
    20701 ttcccatttc gaaaagcaac tacttgatca tgctgagaag ataataagtc tgtaccaaaa
    20761 tgaagataat ctttatcatc gattcccaat agatgtagta atgtcggcaa aacatcgatt
    20821 tctccaccgt attcatgatt gactgtccct ttagtataac caggcatatg gatcatcaat
    20881 ggcactcgtt gcatctgtgc gttgtcaaat tcatcccatg tatctggatc tttaccaaga
    20941 gcgcttgcta aatctttatt atctgtattc gagatcccaa aatgatcccc gtaaatcaca
    21001 aagattgaat tttggtaaat accagatttt ttcaaatacg taaaaaattg ttccaatgat
    21061 tgatccagat aatgtgccgt tcgaacataa ttatctactg tgctattgcc agtattcaaa
    21121 gatggaaagt cgaaattctt gtcatccgta taataaggcg tgtggttggt tacggaaaga
    21181 aatttcgtgt aaaacggctg ttgtagatgc tcaagatatt gggcagattc tctgaataaa
    21241 tctttatcta atatcccata acctaacgtt tcgtcggatt catcaaaata agatcgatca
    21301 aagaaattgt cataacctaa gtttttatat acatgatctc tattccaaaa actagctaca
    21361 ttcccatgga aaacagcgct tgtatagcct tgcttttgtc caaggatcgc tggtgcggct
    21421 tgaaagacat tgtctgaccc aagttctgtg aataatgagc cttgaggtaa accaaatgtg
    21481 ccagtttcca acatattttc agcatcactt gtctttccct gtcctacttc atgaaagaaa
    21541 ttgtcaaagc tgatcgttgc ttgattctgg aaaatactat ttaaaaacgg tgtgacttct
    21601 tgtccgtcta ccttcatatt aatcaaaaac tgctggaaac tttctaaatg gagaacgatc
    21661 acatttttcc ctttagcgat cccaaatgtt tcgggatttg gctctgcata atgtttcttt
    21721 gtataatcta aaacttcatc aatcccatta ctgcttgcat gcgcgcgaac actgctagtc
    21781 attcctgttt tgattccgtc ataaatagta tacgcatcga ttcctagata tttgacaata
    21841 tatgaacggt caaatgttcg ctgcagcaat tgtggacggt tggcttcgct cagcgctaga
    21901 tttcctgaaa aaataagccc tgaaagacag gtaacagcga tagccatcgg tttgccgaca
    21961 gggttgcttt tgataggtat tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca
    22021 gcgatatcca gccagtagat gacatcatgg ggcttcatca aagaaaagga gcttcctgac
    22081 aatccttgcg acactttcga aaagcctaat acagatttga ctgtaatgaa atctgtgaat
    22141 tcccgataaa aaataatatt caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa
    22201 agaatagcta acgctggctt tggcttttta atatacaaag aaaggccaaa aaacaataag
    22261 gtagtcgcaa ttgggttgat ccacaagata aagtactgga tcgtaccttc cacacctaat
    22321 gaaaaatctg catagtaggc aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa
    22381 acgattgcta aacgattttg gcacaatttt ttaagttgtg tcacgtatat cacttctctc
    22441 tattcacatt ttttcttatt ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat
    22501 cttaagattt ttttattctt tctaaagatt attccgtcca cttttcacag cataaaaccg
    22561 ctgcgatgta agcgattaaa ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc
    22621 cacggtattc aaaagccagt ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt
    22681 cttgtcgcag ctccttattt cttgatgcag gacagctttt tcacaacttc ttccttaaac
    22741 ggtgttctcc tgccaactcc tcggccacaa gtcacaatat ttataaaaca tgagaagctg
    22801 ttttttgaaa ttgttccttg tggctcagag ttaaacggca ggctcaagac ctcttgatac
    22861 acggtgttca atcagctgac cctcggtatt agattatgtc aggacgctaa ttttacaacc
    22921 tcttggtaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa
    22981 tataaggagc tattttttga aattgctcct tgtggctcag agttaaacgg caggctcaag
    23041 acctcttgat acacggtgtt caatcagctg accttcggta ttagctcaaa aaacggcaaa
    23101 atatgaggaa ctattttgcc gtttgtttct ctaatactca ggtcaaaacg ctgatttcac
    23161 aacctctgtt tttcattgtc cataggattg atattgtcct tgtgatgact cattcgtaat
    23221 aattgaggct tgattttctt cacttcccgt tatcgtttgt ccactgccag aatctgaagg
    23281 acttgttcct gtcgactcgt ttttttgaga agagacagtt gttttcttga cttgttcatt
    23341 tgtctttttc cattccgcta aacgatcggc gaccactttt ttgtctactt tttcagaata
    23401 agcggtgatc acttttccat ttttcaaacg ggctactttg tcgccatcat gagtcaaaag
    23461 caaaacggtc aaatgcttgt ctttaaattg atattgtctg agagaaatcg cactaagtac
    23521 gtcatcgata ttaataaatt gattttcttc ttttcctttt ggcaaataaa tgtccaattc
    23581 gcctttttcg taattggcag ttattttata ctccgcccac caataagttg agaattcttt
    23641 tttgaaatta tctactgatt ctttgcttgc tacgattttt tctgtttctt tctg
//
LOCUS       DAFTHM010000033        23624 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFTHM010000033 DAFTHM010000000
VERSION     DAFTHM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.033"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            2..74
                     /locus_tag="L7C88_001332"
     tRNA            2..74
                     /locus_tag="L7C88_001332"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="L7C88_001333"
     tRNA            78..150
                     /locus_tag="L7C88_001333"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="L7C88_001334"
     tRNA            155..225
                     /locus_tag="L7C88_001334"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="L7C88_001335"
     tRNA            238..311
                     /locus_tag="L7C88_001335"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="L7C88_001336"
     tRNA            323..394
                     /locus_tag="L7C88_001336"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="L7C88_001337"
     CDS             660..1853
                     /locus_tag="L7C88_001337"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBP9558175.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="L7C88_001338"
     CDS             1983..3455
                     /locus_tag="L7C88_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9558176.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="L7C88_001339"
     CDS             3538..4326
                     /locus_tag="L7C88_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBP9558177.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="L7C88_001340"
     CDS             complement(4393..5061)
                     /locus_tag="L7C88_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBP9558178.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="L7C88_001341"
     CDS             5176..6888
                     /locus_tag="L7C88_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558179.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8660
                     /locus_tag="L7C88_001342"
     CDS             6891..8660
                     /locus_tag="L7C88_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558180.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(8865..9431)
                     /locus_tag="L7C88_001343"
     CDS             complement(8865..9431)
                     /locus_tag="L7C88_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBP9558181.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(9431..10387)
                     /locus_tag="L7C88_001344"
     CDS             complement(9431..10387)
                     /locus_tag="L7C88_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBP9558182.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(10387..11043)
                     /locus_tag="L7C88_001345"
     CDS             complement(10387..11043)
                     /locus_tag="L7C88_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBP9558183.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            11413..13431
                     /locus_tag="L7C88_001346"
     CDS             11413..13431
                     /locus_tag="L7C88_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBP9558184.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    13501..13707
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13858..16272
                     /locus_tag="L7C88_001347"
     CDS             13858..16272
                     /locus_tag="L7C88_001347"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBP9558185.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            16620..18173
                     /locus_tag="L7C88_001348"
     CDS             16620..18173
                     /locus_tag="L7C88_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBP9558186.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(18554..20338)
                     /locus_tag="L7C88_001349"
     CDS             complement(18554..20338)
                     /locus_tag="L7C88_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558187.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(20353..22074)
                     /locus_tag="L7C88_001350"
     CDS             complement(20353..22074)
                     /locus_tag="L7C88_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558188.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            22174..22935
                     /locus_tag="L7C88_001351"
     CDS             22174..22935
                     /locus_tag="L7C88_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBP9558189.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         7474 a         4218 c         4892 g         7040 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattatttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaactgt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcacgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaataa agaggttgtg aaaaagctgt cctgcatcaa gtaataagaa
     8701 cagccaatca aaaacagctt ctcatgtttt tgatttggtt ggacttatta ccgcagatat
     8761 aagcttttga gcaccgtgaa taaagaggtt atgaaatcaa cgctctaacc tgagtattag
     8821 agaaaaaaac gcaaaacata tcatttatgt tttgcgtttt ttatttatct ttttttctca
     8881 atacaatata aaataggcgg ctggttcttt tggttgataa accgataatt cagcacatta
     8941 tatgtttcct gtggcagttt ggaacaaaaa gaatcaacca tatccagttc tttttctcca
     9001 ccttcatgac catagtagac gacaaggatc aatcgtccgc gaggcacaag tcgtttcaat
     9061 atttcttcca tagctgtgcg tgtagtctct ggcatagtga tgattgcttt atcacttttt
     9121 gggagatacc ctagattgaa aatccctgct ttgagatttt gttgttcagc tatcacttct
     9181 cctaacgttt cgtggccttg tagaaacaat gagacacgtt cttctaactg acgctgttct
     9241 agcctttcac gagtagcatc gattgcttgt tgctggatat caaaactata gacatgacca
     9301 gtttttccga tgtgttctgc tagaaaaacc gtatcgtggc cattgcccat cgttgcatct
     9361 acgacgtgat cccctggttg caagatttct tgcagtaatg tatggctgaa atgcaaagca
     9421 gtttgcaaca tcagacgctc acctttttcc gtacatcata ttttccttgg aagctatctc
     9481 tgcgaagaag ttcttcatca attgcattca agacttccca ttttttcaag ctccacattg
     9541 gtccaatcaa ggaatcccac ggcgcatccc ctgtcaaacg atggatgatg atctcttttg
     9601 gtatcatttc cagctggtcg caaatgacat tgacatagtc aggacggctc attaattgaa
     9661 ggcgaccttc atgatagtcc cgcaacattc tcgttttgcg catcagatgc atcaaatgga
     9721 gcttgattcc ttggatatct gaatctaaaa tggtgcgtct gacattttct ttcatcattt
     9781 ctaaactttc gcctggtaat ccgttgatca aatgcgtaca aacacggata ttatgtttgc
     9841 gtaatttagc cacgccatct aaataagttt gataatcatg tgctcggttg atcagttttg
     9901 aagtttcttc aaaagttgtt tgcaatccaa gttctaccca taaatacatc cgctcgttca
     9961 gttcagcaag gtaatcaact acttcatctg gcagacaatc cggtcgtgta ccgactgata
    10021 atcctacgac acctggtaaa ttgactactt gctcaaatcg ttctttgatt atttcaactg
    10081 gcgcatgggt gtttgtaaaa ttttggaaat aaacgatgta ttgttggaca tgaggccatt
    10141 tttgatgcat catgtcgatt tctttctgga attggattgg aagagggtct tcaggtgcaa
    10201 cgatcatgtc tcccgaacca gatacactgc aaaaagtaca accgccatgg gcaacagtcc
    10261 catctcgatt cggacagtca aatcctccat cgatcggcac cttgaaaatt ttcccgccaa
    10321 actcatttcg taaagcgtaa ttccaagaat gatatctttt atttccttct gaataaggaa
    10381 aagtcattaa aagtccttct ttctgtaaga gttatctatt tgttttcttt tttctctata
    10441 cactggataa gtcaggcaca gccaagaaag actgagtaag taaccgccga tgatatcagt
    10501 aggaaaatga acgcccagat aaatgcggct tatcccgaca cttactataa taaacatcat
    10561 cagcaattga agcaatgtgc gtaaggttct tttttgaaca aaagctggaa gcagaaatag
    10621 taaagaaccg taaagaatca tactgcctgc tgcatgtcca ctagggaaac tgtaacttgt
    10681 ttcaactact aagtgcgcca atgaaggacg ctctcgcatg aaaaatagtt tgatcaccgg
    10741 gttgatgatt ccagcaatta caataaatcc agaaacgaac caaaatgttt ctgccctttt
    10801 tttcttatac cacatccata aagccgcaca agcaaataaa atgatgacgg taagaggatt
    10861 accgaattta gtcataaaga gttggtagct gttcagatca ggataagaag ctctgacaat
    10921 gcctgtaaac cactgatcga aaccagaaag ccacgacaga tggaacttta cgatccagcc
    10981 caaaatgaaa aacaggacaa gaaagaagct accagccacc tgaaatgatg ttttatattt
    11041 catacaattc ctcctttgaa gcaatgactt attatagcat ttttggtcca gcgaaaaaaa
    11101 cggtaaagag ataaaaccaa tgtatgattc ctctttgaat aaccaatatt cttataaaaa
    11161 aaataactgt aatcggaaag acattttttg gtaatgcaaa tgaaatgtta gggaaataaa
    11221 atcagtgttt ttcgaaatcc ttttaaacaa gaacgtagac gtaggaagaa cttgaaaatg
    11281 aacagaagtt gttcattacg gtaaattaca atatgattac aaaaaacaac aaagctctta
    11341 aataactttt aataaatatt aagagaagtt ataattatta ataatagata aattgaagtt
    11401 ggaggataga agatggaaaa cattgcaaga aaagaacgga gacgtttaga acagaccaaa
    11461 cgttttcgaa aagcaaaacg aggggcagca atcgtgggaa ctgcgatggt aggctgttct
    11521 gtcgctgccc cattagtaca gccggttcct gttcaagcgg atgaaacacc tgttcagttc
    11581 ggcgcaagaa tcaatacagc ggcatttatc acagaaattg ctacttatgc tcaaccaatc
    11641 gctcaagcca acgatctata tgcatcagtg atgatcgcac aagcagttgt agaaagcggt
    11701 tggggcagta gtgcgttatc tcaagcacct tattataatc tttttgggat aaaaggcagc
    11761 tatcaaggac aaaccgtcta catggatacg cttgaatttt taaataatca atgggtaaat
    11821 aaaaaggagc ctttccgaca atatccttct tttgctgaat ctttcaatga caatgcctat
    11881 gtacttagaa atacttcatt tggcaacggt tattactatg ccggtacttg gaagagcaac
    11941 acgaaatcct atacagatgc gacagcttgt ttgacagggc gttatgcgac tgatcctggt
    12001 tacgcaggca aattaaataa tatcatcgca acttacggat tgacccaata tgatacacca
    12061 gctagcggaa acgcaggcgg tggagcgact acaggtggca ataatactgg aagtgcaggt
    12121 agtactggcg gttcaagcaa ttctggtaat acaaactcag gttcagcaac ttcgaccact
    12181 tatactgtcc aatctggtga ttctgtttgg ggaatctcaa ataaattcgg tatcacaatg
    12241 gatcaattga tccaatggaa caacatccaa aacaatttca tttatccagg acaaaaactg
    12301 acaatcaaag gtagccagga aaatggctct tcgacgaata attccggtaa caataccaat
    12361 tcttcaggaa atgctggtac atcaaacgga ggacaaacaa ctggtgcgaa atacactgtt
    12421 caatctggtg attctgtttg gaagatctca aatgatcacg gaattacgat ggctcaattg
    12481 attgaatgga acaatatcaa gaacaatttc gtttatccag gacaacagct aatcgtatca
    12541 aatggcggtt cttctaatgc tggagcaaat actggctcaa atactgggaa tacaagtggc
    12601 tctagttcgt ccagctcaag ttcttctaat acagcttcag gaacgaaata tacagttaaa
    12661 gccggagact ctgtttggag cgtctcaaat aaatacggaa ttacgatggc tcagctaatc
    12721 caatggaaca atatccaaaa taactttatc tacccaggac aacaactgac tgtttcaaac
    12781 agtggatcaa caaacagcac gtcaggtaat acaggttcgt caaccaatac aaataacagc
    12841 agttcagtta atactggcag cagttcgtct caaggcactt ataccgtgaa agcaggtgaa
    12901 tctgtttgga gcgtggcaaa taaaaacggc atcacgatgg atcagttaat cgaatggaat
    12961 aatatcaaaa acaacttcat ttatccagga cagcaattga tcgttaaagg tggaacttcg
    13021 gcaaatacaa atacaggttc aactacttct gcagcgaaac caaatacacc gaatacgtct
    13081 gctacgacaa gtacatcatc cactggtaat acgatgtata ccgtgaaagc gggcgagtca
    13141 gtttggagcg tagcgaacaa acatcatatc acgatggatc agttaatcga atggaataat
    13201 atcaaaaata atttcatcta tccaggacag caagtgattg tgaagaaagg ttcatctcaa
    13261 tcaacaaacc aacaatcagt tactggttcg aaaacctata ctgtgaaatc tggagaatct
    13321 gtttggagtg ttgctgacag tcatggaatt acaatggctc aactaatcga atggaacaat
    13381 attaagaaca actttattta tccaggtcaa acgttgattg tagctaaata aaatagctgt
    13441 tcgaagaaat aacgattgaa ttccacaaaa atatttgtta ctataaggct acttaaatat
    13501 gacaacactt gaaaaggaag tagtaaaaag actgaagttt cagagagcgc atggctggtg
    13561 agaatgtgca cggatgcttt tgaactcgcc tttgagttgc ccttgctgaa tacccgagta
    13621 agcaagcggc ggtgacggcc gttacaacgt tcgaggcctt ttcactaagg taaaattagg
    13681 tggtaccgcg tagattacgt cctataaaaa gagcaatctt tttataggat ttttttattt
    13741 cttttgtgaa gtttgagaaa acaaagcaaa aggaaataaa aataaacaga ttctgccggt
    13801 tttttcgtta tatttataat agaaacaagt gttttcaata gaacaggagg acagcaaatg
    13861 agttacaatc ataaagaaat tgagaaaaaa tggcaaaaat actgggcaaa aacgaatact
    13921 ttcaacaccc atgatgatcc tgaaaagcca aaattttacg cactggatat gtttccctat
    13981 ccatccggtc aagggctaca tgtagggcat cctgaaggtt atacggcaac ggatatcctt
    14041 tcacgtgtga aaagaagtca aggatacaac gtgctgcatc caatggggtg ggatgcattc
    14101 ggtctgcctg ctgaacaata tgcgctagat acaggaaacg atccagctga gtttacccaa
    14161 aaaaatatcg aaacattccg acgccaaatc aattctttag gatttagtta tgactggaat
    14221 cgcgaagtga atacaactga tccggagtat tataaatgga cacaatggat ctttacgaag
    14281 ctttatgaaa aaggtctagc ttatgaagca gaagtagcgg taaactgggt acctgaatta
    14341 ggaacagtta tttcaaatga agaagtgatc gatgggaaaa gtgaacgtgg tggctatgat
    14401 gtagtcagaa aaccaatgcg ccaatggatg ctgaaaatca ctgcttatgc tgatcgctta
    14461 ttggatgatc tagaattagt tgattggcca gaaagcatta aagaaatgca aagaaattgg
    14521 atcggtcgtt cagtaggagc aaatattgaa tttaaagtgg ctggtacgga taaatcctat
    14581 accgtattta cgacacgacc agatactcta ttcggtgcaa cttactcggt tcttgcacct
    14641 gaactagatc ttgttagaga aattacgacc cctgaacaaa aagctgctgt agaagcttat
    14701 atcgaagaga cagctaaaaa atcagatcta aagagaacgg atcttgcaaa agaaaaaaca
    14761 ggagtattta ctggtgctta tgcaatcaat ccagttaatg gcaaggaaat cccaatctgg
    14821 atcgccgatt atgtattatc ttcatacggc acaggagcca tcatggctgt tccagcacat
    14881 gatgaacgtg actttgaatt cgctcaaact ttcggactag aaattcttcc agttatcgaa
    14941 ggtggagatg ttgaaaaagc tgcttacaca gaagatggta cgcacatcaa ctctgaattt
    15001 ctagacggca tgaacaaaca agaagcaatc gataaaatga atgaatggct agaagaaaat
    15061 ggcgtaggga aaaaagaagt cagctatcgc ttacgtgact ggctattctc ccgtcaacgt
    15121 tactggggtg aaccaatccc aatcatccat tgggaggacg gaacagtcac agctgtccca
    15181 gaagaagagc taccattacg gttgcctaag acaaaaaaca tcaagccaag cggtactgga
    15241 gaatctccat tagcaaatat cgaggagtgg gtcaatgtcg ttgatcctgt aacaggtaaa
    15301 aaaggccgtc gcgaaacgaa tacaatgcca caatgggcag gaagctcatg gtattacctg
    15361 cgttatatcg accctcataa caaaaaagaa ctagcagatt atgaaaagtt gaagcgttgg
    15421 ctaccagttg acatctacat tggtggagca gaacatgcgg tacttcattt actatatgca
    15481 cgattctggc ataaattctt atacgatatc ggtgttgttc ctacaaaaga accattccaa
    15541 aaactataca atcaaggaat gatcttaggc gaaaacaacg aaaaaatgtc aaaatctcgt
    15601 ggtaatgtag tcaatcctga tgatgtggtc gaaacttacg gtgcagatac actgcgcatg
    15661 tacgaaatgt tcatggggcc attagatgct tcgattgctt ggagcgaaaa tggcttagaa
    15721 ggaagccgta aattcttgga tcgtgtatgg cgtttgatcg ttgatgagaa caataaaatg
    15781 cgtgaccgta tcactacatt gaatgatggc aagcttgata aagtgtatca tcaaacagtg
    15841 aaaaaagtga cagaagacta tgaaaatctt catttcaata cagcaatctc ccaattgatg
    15901 gtctttatca atgaagccta taaagtggac gctctgcctt atgaatatat cgaaggattt
    15961 gttcaactac tcgcaccgat tgctcctcac atgggtgaag aactatgggc aatccttgga
    16021 aatgatggtg gtatttctta cgcaccatgg ccaacatacg atgaagcagc acttgttgaa
    16081 gacgaagtag aagttgtttt ccaagtaaac ggtaaagttc gtgcgaaaag caatgttccc
    16141 cgagacttag gaaaagatga gctagaaaaa gcagcattag ccaatgaaat agtgcaagaa
    16201 tatattgaag gcaaaacagt cagaaaagtt attgcggtac caaacaagtt agtcaatatc
    16261 gttgctaatt aattggctct ttgtcaataa ggactgatga gttgtgcaaa atcaaatctg
    16321 ggccagaatg aacttcattc tgtctcagat tttttgttat ttcaaattga ttaattgatt
    16381 gatcaaaaag gttttgattt tcatgttctc aaacacgttc aatgtctttt tcttctgaat
    16441 ggtcttgtaa gagatctctg taatcatcaa atttttgtct attaatctta gtattttttg
    16501 atgtataaac tacctgaaat tgagagtaca taccaaattc ataaattttt tattagtggg
    16561 actagtgatt gtatggattt tgacgcataa tgaatgaagt atgagaaaag gagagacaaa
    16621 tggatcaaga actatttatt atcgaagtat tatcagctaa acaaaaaatt atcgagaaag
    16681 cgaaaaaaag agcgaaaaga ataatgttca agcttttaag cttagtattt ttctctggtt
    16741 tgcttttttt cggagctgta tcgttcctat atcgccatat gagtgcagta gtccgttcag
    16801 ctgaagggat gcaaaaatta aataatttgt atcacttttc gtggggagtt ggcggaataa
    16861 caattgttgt gcttattgtt tttcttctac ttatttggct ccgttaccat caattgtcgc
    16921 gtcatttcga tcaatggctt agtcaaagag cacaacagtt tttacataat aaaccaactt
    16981 ctcaagatga tgactatctt tattttgaga agacttcgac gagtcaagct tttcggatac
    17041 aaaaaagtga ttgccagtta ttgctgagat cacttgatga tttacctatc tacttaggcg
    17101 aaagcaaatc aaaattcgga atgaacacat tccatatttt tttactagaa aacgaaccca
    17161 gatgggaaaa aagccagtct tcgcctggtg gatacctgac aactaagatg agtacattag
    17221 tcactggttt tttcctcatt cttttagctg gaacaatcta ttatgggaga tacactcagc
    17281 caaaaatgtc ttctcatata aatgctgctt ctcacatgac aatgaactca actaacgata
    17341 cgcatataca aaagacaaat gaagggttgt tagctgatcc taagcaaaag gtaaatttga
    17401 caacacaaaa gataaatgat ctcaaacttg atacagagac gcactctctc tatatgacaa
    17461 cagatagtgg tgctaattgg gtatttgtgc cgattgattc gcaatggttg cgttttggcg
    17521 aatacaccct gacaacgggg ctgattcctg aaggttattg gatggacaac acatatgata
    17581 tttccgccga tttctcatgg tttatctatt cttctgggga tgatgtacgt ctgctgactt
    17641 caagagataa tggtaaaaca tggcaaacgt ctattatcac ccaatcagtt cagccgatac
    17701 gttatcgaaa agcggtattt tatggcaacg atggtctatt tatctgtaca tcagccagtg
    17761 ggatgtctgc agaaactttg tacatttaca ctactatgga tggcggaatc acttggataa
    17821 aaagtggaag tacaatgatc aatcagccag tacaaaatgt cagcttcgtt acaacttctt
    17881 taggttttgt ttcgacacgt gaaagtttgt tttatacaaa caacggagga cgctcattca
    17941 aagaatcagt tctgtcgatt ccggaaaact atcagacagg ggggatagat ctttttcaat
    18001 caccaaatga agttactcaa ataagcgcga atacgttaga gacaaaattt tatttgttga
    18061 aaaaaggacc aatcgatgca gggaaaatgt ttgcctgcct cttccgttca actgataacg
    18121 gggaaacatg gcaattcgtt cagcaactat cgcaagtaga acaaggagat taaagaagag
    18181 agattgtgag cctgacgttc agcaccgagt cacaagaaac aaattcaaaa aacagcttct
    18241 catatttgtt gaatagtgta actcgtgatt cggagttgac aagagcaaca agaagcgatt
    18301 ttgaagtata gcttctcgta ttttacaaga tcgtgtctta ttgccgatag gttgtctctt
    18361 gaacaccgtt tattcgtaaa aagggattgt gacaagtctt ttgtcactac ttaccgaacg
    18421 aaactgaagg agctatccaa aaagtatcat tagtattatt ctttgtgttt ctagtggcac
    18481 cactagtaca tttaaaaaag ctatcgatca tggactaatc atacatgatc gatagctttt
    18541 tagataatgt ttgttacgct atctgaaatt gactattata aagactggca taaagcgttg
    18601 gtgattggag tagttcagaa tgtgttcctt tttcgacgat atcgccattc ttcattacaa
    18661 ggatcatgtc tgcattttca atcgttgaca aacggtgtgc aatcacaaaa cttgtcctat
    18721 cttttgtcac agcttccatt gcttgctgaa tcaatgcttc tgttcgtgta tctacgctag
    18781 aagttgcttc atctaaaata acgacaggag gattcgctag aatgactcga gcaattgtca
    18841 ataattgttg ctgtccttga gataacgtgc cgttttcgct agaaatgatc gtatcatatc
    18901 cgtctggcag tgttcgaata aagtgatcac attgtgcgat ttcagccgct tcgataattt
    18961 gttctcttgt ggcatccatt ttcccgtagg cgatattatc agctaccgtt ccttcaaaca
    19021 gccaggtatt ttgtaaaacc atcccaaaag aacgacgtag ttctccacgt gaaagcttgg
    19081 taatatcaag accgtcgaat tcgatctttc ctttattcag ttcataaaaa cgcatcagca
    19141 gattgactaa agtcgttttt cctgcaccag ttggaccaac gatcgctacc gtttgttttg
    19201 gctttactga aaaatcgact tgattcatca atattttatc tgatgtgtaa ccaaactgta
    19261 catttttgaa agctattttt cctttcggtt gttctaaaag tcttgcatct ggaaggtctg
    19321 gaatttcatc tgtttcatct aatatctcaa atatcctatc gattgctgcc attgcggatt
    19381 ggatcgagtt gatcacataa gaagcggtag aaattggttc agaaatctga ttgatgtact
    19441 gaagataagc ttgtaagaag ccgatcgtca caccacctga tagaacaagc atagcaccga
    19501 ataccgcact tatgatgaag gcgagttgat taatgaaacg aatggccgga tagatagcac
    19561 agttcataaa ttgagcacgt ttaaaagcgt tgtattgctt tttatttact tcgtgtatag
    19621 cagcttctgc atgagcttgc tgattgaatg ttttgaccac tagattacca gctaagattt
    19681 cttccattcg attatttaaa acacccagtt catactgatt ctgttcagaa atctgtttgt
    19741 ttttgttcgc aatcttagtt gtaacaattg aactgccaac gatcagcaat aagacgagca
    19801 aagtaagctt gctttcgata taaaacagca tcagaccagc agcagctatt gttacgacag
    19861 aagtaaaaaa ttgattgata cctgtcaata acacttgaga aagttgattg agaccggtag
    19921 ttgtccgact aatgatgtca cctacttgat gattgtcaaa aaacgacatc ggtaatgttt
    19981 tgaatttttt tgtgatttct tttcgcaccc tcaatgtgat cttttcgctt aacgctgcca
    20041 ttgtccgttc ctgaataaat gaagtgatgc tgcttaagac tgaacagccg atcagcaata
    20101 agacagggaa caacaatgct tgtttgatat cactgaaaga aagctgtcca atacctgttt
    20161 ttcttatttc tgataagaga tcatcgatcc cgattcccat gatcaagggc atggctacga
    20221 ctaataggtt cccgaataaa ctgcatagaa acaatccgta aaaatattta tgttcaggtt
    20281 tgatcatttt ccaaaaacgt atcaaagcac gcgtgttcaa cgtttttttc ttttccatcg
    20341 tatcccttct ttctatattc cttgtgattt tgcaaactcc tgataagttt ggcaattaga
    20401 cagtagttct tcatgagtac cttgtccaac gatttttcct tcatctaaaa caatgatgtt
    20461 atctgcttgt tggattgtac tgaggcgttg agcaacaatc acgagagttt tctccgacat
    20521 gtgtttatga agggctgctc ttaatgctgc atctgtttta tagtctaaag cggagaaact
    20581 atcatcgaat acatagatct ctgctggttt gatcaacgct cgagcaatac atatccgctg
    20641 tttctggccc cctgaataat tagaaccgcc ttgagcaaca aagctgtcca atccgtcagg
    20701 aagggtgtcc actagttctt ctaattgagc gatcttgatc gctttagaca actcttctgt
    20761 tgaggcatat tcatttccca tctgcaagtt gcttaaaatt gtcccgctga ataagaaagc
    20821 cttctgaggg acataactga tgtgggagcg gatctgttct tgagtcattt gagtaagagg
    20881 aataccacca agggttactt ttcctatcgt agggtcacta agtctcaaga gaagtttcgc
    20941 caaactactt tttccagatc cggtcccgcc aacgatcgct gttgtttttc ctttaggtat
    21001 tgtgaaatca atatcttcta gaactggatc agagatttca gtatatttaa atgtgacatg
    21061 ttcaaaagca gctgcatttg tctgatcaaa ggttggttca gctactgttt tgatcgtctc
    21121 ttcctcaatt tcgatctctg cttgcagtat ttcttctatc cgtcgtaatg aggcaaacga
    21181 tttagggata atgaccaata ccatagctgc gatcatcaag taagcaagtg tcagcataga
    21241 gtattcgact acagcagtca cgacaccgat ttgtaatgct ccttctgcta caagatttcc
    21301 gccaaaccac aaaatagaag cataaacgat tcccatgagc aaaaaagcaa ttggagtgac
    21361 ccaagcaaat attcggttca ctttgatcat ttgattagca tagtcagcaa agctcttatt
    21421 cgttcgcttt tcttcatatg attgattatc aaaggcacgg atcatattaa tcccagtaaa
    21481 gaattctctc aatgtgatgg tgatccgatc catttttggc tggatactca aagataaagg
    21541 tgcccctcgt ttcatcagtc gataaacaat ccatacataa aaaacaacag agatcaatgt
    21601 aacccatgtt agtaatagag aataacgaaa catcatgaga atggtgaaaa cgcaaataac
    21661 cggtgctggt aagatcattt ggcaaaataa aacaatcatt tgctggacat tatcgacatc
    21721 attcgtcatt cttgtcaaaa gagatccaga actaaaacga ctgatatcct tcattgacag
    21781 ctgttggaat ttacggaaat atttctcccg cgtttggaat ccaaacctag cggaagccaa
    21841 tgctgaaaag taactagagg caactgcagc gattgttcct agaaacgcta caagcagcat
    21901 ttcaactcca atttttttta taactgaggc ttcgccactt gctatacctg tgtcgatcag
    21961 ctttgctact aattttggta cacctaatgt accggcgatt tctaaacaga tcatcacaaa
    22021 ggtaaggaga gcgagtcctt tgtttttctg taagaatgtt tttaagatag acatattatt
    22081 cctccttttt tcctgatact tttcgattct ataccttcaa gtaacttgaa ggtcaataga
    22141 aaaaagaata aactgaaaaa gaggtgagaa aaaatgaaaa aaatgtatac gattggccaa
    22201 gtatcggaac tatttgattt gccaaaatca acgatccgct attgggatga acaaggatta
    22261 atccgttcaa gtagacaaga agagaatgat tatcgattgt ttgatatcga tgatattttt
    22321 atgctttatg atatcgtttt ttatagaaaa ttagatatac cgatcaaaca gatgaagaat
    22381 ttatatggaa aaacattgac ggagttatat gagacacttg atgaaacaga aagaagaatc
    22441 cataaagaac tggtggtgat gaaacaaaaa caaaaagaga taagggagca aaaaaaacag
    22501 ttgaaattga tgatcgatac aaacgaggaa gaatttcctg tagaagagat cccttttgac
    22561 tgtatgatct caacggagtt tgaagatatt gtggaaatca aaaaatttct acctaactat
    22621 tcaagctttg ggatgatgag tatgccagct tccagttcac agacgatgta tggatttttt
    22681 atcgacccta gtgaagtaca tttatttact caagacgtga tttgggagaa aaaagatacg
    22741 gctgtttatc gtcgattctt attgaaatcc gagatgaacc atgcggaacg taataatatt
    22801 ttagaaatca gagaaagaat gtatgaaaaa ggatggaaaa caggagaagt gatcggccag
    22861 tatctattga cgaatacgga tgaaaacaat atcagaactg aatattatca tgcatggata
    22921 gaaatgaaaa aataggaaat atgtgtttaa gataactcga aaatgatggt tgttttagtt
    22981 ataaagaaaa attttctggt tcgattacgg gtttaatgtg ggggattatt agtcgtggat
    23041 agatagaatt ttagtttttt agaggaaata tgtctttaaa aatggaatgg ttgcaattct
    23101 tagcgatata tacgatgtaa ttgtcctctt aaaaaagtat ggaaaaataa ttgtattggg
    23161 tgttatgtat aattcatggt gaactgagac taatgagaag aaaaattcat attgttatga
    23221 gtgagattgt atcagatgag aatgataaat taaataggtg cataaaagca ttacacttaa
    23281 aatacattgt tgcttacatt attacaatat gttaataagg caaaaataaa tagatggatt
    23341 gaataaacat attttttaat caaatagtcc ctactgtgac tttcctcagc tatcggtgat
    23401 actaccgata gcattttttt gcttataaaa taattataag tatttagaga tttttcttct
    23461 aacattcttc aaacaagaaa aatcacaaag gttattgtta tttttatata ttctttttaa
    23521 gaatgattgt ttttttatag aaattttaaa aaataaaaca cgttattgat ggatagttag
    23581 tttgttattt ggtaatatta tagaagttga ctggtagtga ttta
//
LOCUS       DAFTHM010000034        23542 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFTHM010000034 DAFTHM010000000
VERSION     DAFTHM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.034"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            74..886
                     /locus_tag="L7C88_001352"
     CDS             74..886
                     /locus_tag="L7C88_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBP9558190.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            883..1683
                     /locus_tag="L7C88_001353"
     CDS             883..1683
                     /locus_tag="L7C88_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBP9558191.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1844..3112
                     /gene="rseP"
                     /locus_tag="L7C88_001354"
     CDS             1844..3112
                     /gene="rseP"
                     /locus_tag="L7C88_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBP9558192.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3180..4889
                     /locus_tag="L7C88_001355"
     CDS             3180..4889
                     /locus_tag="L7C88_001355"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBP9558193.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            5101..9459
                     /locus_tag="L7C88_001356"
     CDS             5101..9459
                     /locus_tag="L7C88_001356"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBP9558194.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9604..10077
                     /gene="rimP"
                     /locus_tag="L7C88_001357"
     CDS             9604..10077
                     /gene="rimP"
                     /locus_tag="L7C88_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBP9558195.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10100..11275
                     /gene="nusA"
                     /locus_tag="L7C88_001358"
     CDS             10100..11275
                     /gene="nusA"
                     /locus_tag="L7C88_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBP9558196.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11297..11590
                     /locus_tag="L7C88_001359"
     CDS             11297..11590
                     /locus_tag="L7C88_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBP9558197.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11587..11898
                     /locus_tag="L7C88_001360"
     CDS             11587..11898
                     /locus_tag="L7C88_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBP9558198.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11911..14217
                     /gene="infB"
                     /locus_tag="L7C88_001361"
     CDS             11911..14217
                     /gene="infB"
                     /locus_tag="L7C88_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBP9558199.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14244..14591
                     /gene="rbfA"
                     /locus_tag="L7C88_001362"
     CDS             14244..14591
                     /gene="rbfA"
                     /locus_tag="L7C88_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBP9558200.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14748..14921)
                     /locus_tag="L7C88_001363"
     CDS             complement(14748..14921)
                     /locus_tag="L7C88_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9558201.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            15369..17731
                     /locus_tag="L7C88_001364"
                     /pseudo
     CDS             15369..17731
                     /locus_tag="L7C88_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            18099..19022
                     /gene="truB"
                     /locus_tag="L7C88_001365"
     CDS             18099..19022
                     /gene="truB"
                     /locus_tag="L7C88_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBP9558202.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            19026..19967
                     /gene="ribF"
                     /locus_tag="L7C88_001366"
     CDS             19026..19967
                     /gene="ribF"
                     /locus_tag="L7C88_001366"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBP9558203.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            20319..21104
                     /locus_tag="L7C88_001367"
     CDS             20319..21104
                     /locus_tag="L7C88_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBP9558204.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            21117..21968
                     /locus_tag="L7C88_001368"
     CDS             21117..21968
                     /locus_tag="L7C88_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBP9558205.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(22092..22544)
                     /locus_tag="L7C88_001369"
     CDS             complement(22092..22544)
                     /locus_tag="L7C88_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558206.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(23009..23377)
                     /locus_tag="L7C88_001370"
     CDS             complement(23009..23377)
                     /locus_tag="L7C88_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBP9558207.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
BASE COUNT         7995 a         4083 c         5099 g         6365 t
ORIGIN      
        1 cataggaaaa acagttagat attgctataa tacttaagat agtgggaatc ttttaagtat
       61 aggaggaaaa agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag
      121 cgaatttcaa tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg
      181 caatggtcgt tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat
      241 ggaaacagta aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct
      301 ttatgccttt tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca
      361 actacctgtc gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt
      421 tcatgtcatg ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc
      481 aattgagcaa acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag
      541 cagagcagag atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat
      601 acacgcagaa gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc
      661 taaagagtta caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa
      721 ttttctgtta tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga
      781 ttttgatggt gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt
      841 cggcggtgta aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtggtc
      901 acagcagccg tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt
      961 gagcttacag cagcaatctt agcagtaata ggagtttacg agctgtttcg gatgaaagga
     1021 ttgacactct taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg
     1081 ccaaaagaaa gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat
     1141 cttatagtta tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat
     1201 gaagcaggtt ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc
     1261 aatgcacgaa cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact
     1321 gatatcggag catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt
     1381 tcgcccaaca aaacgattga aggtgcgctc ggtggtattg gtagtgctgt tgtagtcgca
     1441 tttctttatt tattgctata cccagcaaaa gaactattta atcatggtat gtttgtcatg
     1501 cttctgatga cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca
     1561 atcaaacgtc attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc
     1621 ttagaccgtt tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt
     1681 tagtaagtat acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca
     1741 ttatattgat actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt
     1801 gttttataaa aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac
     1861 atttatcatc gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc
     1921 gaaacgatca ggaatcctcg ttcgcgaatt tgctatcggt atgggtccga aaatttatgg
     1981 gcatcaagca aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt
     2041 tcgaatggca ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct
     2101 tttactaaat tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac
     2161 aaatgctatc ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg
     2221 ttatgtgaat ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat
     2281 tattgaaaac gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc
     2341 taaattgtgg cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc
     2401 aatcctgtta ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa
     2461 tcgcgtagga gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga
     2521 tgaggtagtc agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat
     2581 tacgaaaaat ccggataaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc
     2641 tgtcgacgtg acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat
     2701 aaaagcccca atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt
     2761 cagcggttca ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga
     2821 taaattaggc ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt
     2881 aacaactgtt attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct
     2941 tccgattcct gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg
     3001 gaaaccatta agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat
     3061 gttgttgatg gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt
     3121 gacaaatagg gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa
     3181 tgagacaatc aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat
     3241 taagccatca aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt
     3301 catatctgcc attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat
     3361 ttgaaaaaat cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg
     3421 aagaatccgg gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg
     3481 atcgaaaaat gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg
     3541 aaatcaattc atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg
     3601 acgaaaaacg acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcgt
     3661 attctttcca tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct
     3721 acaccgaagt attcaagcgt tgtggcttag aatttcgctc gattatcgga gacggtggcg
     3781 caatgggcgg gaaagactca aaagaattca tggcgatctc agaaatcggg gaggatacga
     3841 tctgttattc gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg
     3901 tatcaaaaaa atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa
     3961 aatcaattga cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg
     4021 tattgttcat tgcggatgaa caacctgtcc ttgttttggt acgcggagac catgaagtca
     4081 atgacgtaaa actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag
     4141 aagcacaaaa atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg
     4201 acgtaaaagt atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga
     4261 acgaaacagg attccactat aaaaatgtga atccagaacg cgatttcact gtactttctt
     4321 atgaagatct tcgttttgta caagaaggag atccttcacc agacaacaat ggtgttcttg
     4381 cctttactcg aggaatcgaa atcggacata tcttcaaaat cggcactcgt tacagtgaat
     4441 ctatgggagc aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt
     4501 atggtatcgg tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag
     4561 gaatcaactg gccaaaagga attgcgccat ttgatttgca tatcgtccaa atgaatctaa
     4621 aagacgaata ccaaacaaac ctgacgaatg aactagaaga agcgatgaca aaagctggct
     4681 atgaagtact ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt
     4741 tgattggctg tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag
     4801 tgaaaatcaa gaaaactggc gaaatggttg aagtacgtaa agaagaattg gtgaatactt
     4861 taccaatcct cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc
     4921 tgaatcagct gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa
     4981 tcgcagttcc aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga
     5041 aaaagaagag gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct
     5101 ttgtcagaaa aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca
     5161 gaaaaaaatc atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa
     5221 tcgcgtttat gggaatttac gctgcatttt tccaaaattt tgcctattat gctatatcgg
     5281 tcattgactc agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc
     5341 ttagcagatg accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg
     5401 gaaaatcagc aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg
     5461 ataaaagatc gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag
     5521 caacaatact tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt
     5581 atcgaaccag aagtggatga gcagcaagcg gaacgagtat tgaaactttt tgaagaacgc
     5641 aaacaagaac aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa
     5701 caaaagaaaa aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccacatccag
     5761 ctaggacgaa atattccagc cgatgaacca acgacaccaa tgatcagtat cgttgaagaa
     5821 gaacgaagag tcacacttga ggggtacgta ttcgacaaag aagtcagaga actacgttca
     5881 aaacgcaaga tcttgacttt gaaaatcaca gattatactt catcatttat cgtcaaaaaa
     5941 ttctcgaacg gcgaaaaaga tgaacaagta tttgatgcga tcagtgtcgg tagctggtta
     6001 aaggtacgag gaagtattca agaagatacg tttgtccgtg atttggtcat gaatgcgcaa
     6061 gatatcatag aagtcaaaca tacacctcgc aaagattatg ctcctgaagg ggaaaaacga
     6121 gtagagcttc atgttcatag caatatgagt acgatggatg caacaaacag catctctgat
     6181 cttgtggcac aagcagggaa atggggacac cgagctatcg ccattacaga ccacggtggt
     6241 gcgcaagcct ttccggaagc acatagtgct ggaaaaaaag caggtgtgaa aatcttatac
     6301 ggcgtggaag cgaatgtcgt agatgatggt gtcccaattg cttataatga tgcacatgaa
     6361 gcattgagtg aagccacata tgtcgtattt gacgtggaaa cgacaggatt gtctgcagta
     6421 tatgacacga tcatcgagct agccgcagtc aaaatgtata aaggaaatgt gatcgaaagc
     6481 tttgatgaat ttatcgatcc aggacatcct ttgtcacgaa caacggtaga tctgactggt
     6541 atcacggatg gaatggttcg aggatcaaag tcggaagaag aagtattgcg gatgttcctt
     6601 gaattttcaa aagatacaat tttggtagcc cacaacgcgg cttttgatat ggggttcttg
     6661 aatactagct acgcaaggta tggtattcct gaagcggcca atccagtcat tgatacgttg
     6721 gaattagcta gatatctgta tcctcaattc aaacgtttcg gattaggtgt gttatctaaa
     6781 aaatttggtg tcagcttgga acagcatcac cgagcaatct atgatgctga agcaactggt
     6841 cacttagcat ggatctttgt gaaagaggca atggacaatc ataacatgct ttatcatgat
     6901 cagctaaatg agcatatcgg agaaggagat tcttacaaaa gggctcgacc tttccatgta
     6961 acgattttag caaaaaatca ggcaggactg aaagatttgt tcaaactgat ttcaatgtcg
     7021 aatgtcgaat acttcgaacg cgtcccacga ataccacgct cccaattgaa aaagatgcgt
     7081 gaaaatctat tgatcggctc agcttgtgat aagggagaaa tattcgaagc catgatgcaa
     7141 aaaggggtag aagaggcaag aaaccgagca aaattctacg attatattga agttatgcca
     7201 aaagcggtct atgcgccttt gatcgagcaa gaattggtaa aaaatgaaca tgatttggaa
     7261 gaaattatcc aaaatttggt agaaatcgga aaaagtttgg ataaaatcgt tgttgcaaca
     7321 ggtaatgtac attatctgaa cgaagaagat gccatttacc gaaaaatttt gatcaattct
     7381 atgggcggag cgaatccgtt gaatcgtcat agtttgccgg atgtccattt ccgaacaacc
     7441 gatgagatgc taactgcatt tcacttttta ggggaagaaa cagcgaaaga gatcgtagta
     7501 gaaaatacga ataaaatcgc agatatctgc gaagaagtga ttccagtcaa agatgaactt
     7561 tatacaccga agattccagg ttcagaagat gaaatatcag aattgagtta cacaaaagca
     7621 aaacaaatgt acggagatcc gttacctgag atcattcaaa aacgattaaa aaaagagttg
     7681 aattctatta atggtaatgg cttctcggtt atttatctga tcgcccaaaa actagtgcat
     7741 aaaagtaatg aagatggcta tctagtaggt tcacgtggct ctgttggctc tagctttgtt
     7801 gcgacgatga caggaatcac tgaagttaat ccgttagccc ctcattatta ttgtccagag
     7861 tgccaatatt ccgagttttt tgaagatggt acgtatggtt ctggatttga catgccagaa
     7921 aaacaatgtc caaaatgtgg tgcacgctta aacaaagacg gtcatgatat tccatttgag
     7981 acatttttag gattccatgg agacaaagtg cccgatattg atttgaactt ctcaggtgat
     8041 tatcaagcag aagcccataa ctatacgaaa gtattgtttg gcgaagacta tgtttaccgt
     8101 gccggaacga ttggtacagt cgccgacaaa acagcatatg gctatgtaaa aggatacgaa
     8161 agggacaata atctgcagtt tcgaagtgca gaagtcgaca gattagcaaa aggcgctact
     8221 ggagtcaaac ggacaaccgg ccagcatcca ggggggatca tcgttattcc cgattatatg
     8281 gatgtctatg attttacgcc gatccaatat ccagcagacg atcaaaattc ggaatggaaa
     8341 acgactcatt ttgattttca ctcgattcac gataatgtat tgaaattaga tattctaggg
     8401 catgatgacc caactgttat tcggatgctt caagatttat cagggatcga tccacaaacg
     8461 atccctacgg atgacccgga agtgatgcgg atatttgccg gtcctgaagt acttggagta
     8521 agtcaggaac aaatttattc caaaacaggg acattaggta ttccagaatt cggcactcgt
     8581 tttgttcgag ggatgctaga agaaacgcat cctacaactt ttgcagaact actgcaaatt
     8641 tccggactat ctcatggtac agacgtatgg ttaggaaatg cggaagaatt gattcgacga
     8701 ggagatgcga cactggcgga agtaatcggc tgtcgtgatg atattatggt ttatttgatc
     8761 catgctggat tagatagcgg gatggcattt aaaatcatgg aaactgttcg taaaggacaa
     8821 tggaacaaga tccctgatga attgcgagaa acctatctat cggcgatgaa agaaaataat
     8881 gtgcccgact ggtatatcga ttcttgttca aaaatcaaat atatgtttcc gaaagcccat
     8941 gctgcagctt acgtattgat ggctcttcgt gtcgcttatt tcaaggttta tttccctatt
     9001 ttgtattact gtgcatactt ttctgtacgt gcagacgact ttgatctagt ctccatgtgc
     9061 aaaggaaaag atgctgtgaa acaagcaatg aaagaaatca cggacaaagg attagatgct
     9121 tccgtaaaag aaaagaatca actgacagtg ctggagttag ccaatgaaat gctggaacga
     9181 ggattcaaat ttggaatgat tgatttgtat aaatcggatg ccgttaactt tgttattgaa
     9241 ggtgatacgt tgatcgcacc atttagagct gtcccaagtt tgggaaccaa cgtggcaaaa
     9301 caaatcgttg aagcaagaaa agacggtcca tttttatcca aagaagatct tgccacccgc
     9361 ggtaaagttt caaaaacatt gatcgaatat atgaacgaca atggcgtatt gaaagatcta
     9421 ccagatgaaa atcaattatc gttattcgat atgctataag catctgtttt cctgtctgct
     9481 tgtaatttta agcagagtat ggtatagttc ttataggtaa tgatactaac tgtgagtgag
     9541 cggatttttc gctcactctt tttaatggaa ttacgcactt aattttttaa ggaggcgaaa
     9601 cttttgagta gcgtcgttga aacagtcaca gaaatggtga caccgatttt agatgaacaa
     9661 aattttgaac ttgtcgaagt cgaatttgta aaagaaggaa aaagctggtt cttacgagta
     9721 tttattgaca aagaaggcgg tatcgatatc gaagaatgcg cctttgtcag tgagaaactg
     9781 agtgaaaaac ttgatgcagc agatccagat ccgattcctc aagcttattt cctggaggta
     9841 tcctccccgg gagcagagcg gccattgaaa aaagaaagcg actatgaaaa ggcacttggt
     9901 gattatgtcc atgtctcctt ataccaacca gtagatggcg aaaaacaata tgaaggattt
     9961 cttcaatcat ttgatgctga acagcttaca ttgaaaatac gcataaaaac acgagaaaaa
    10021 gaattgactt ttgaccgaaa aaatattgca aaagctcgct tagctatcca attttaatca
    10081 cggagaggaa tcagaaaaaa tgagtaaaga aatgttaaat gcgttagacg ctttagaagc
    10141 tgaaaaaggg atctcaaaag aaatcgtgat cgatgcttta gaagcagcat tggtttctgc
    10201 atacaaacgt cactatggcc aagcacaaaa cgtcgaagtg gaatttgatc agaaaaaagg
    10261 aaagatccat gtctatgcgg taaaagaagt aacggaagaa gtgatggatt cacagttgga
    10321 agtctcattg aaagatgcac ttttaatcaa tccagcatat gagatcggtg atacgatccg
    10381 ttttgaagta acaccaaaag attttgggcg gatcgctgcg caaacggcta aacaagttat
    10441 tttacagcgt gtacgtgaag cagaaagaac gattatttat aacgaattca gtgcttatga
    10501 aaaagacatc atgcaaggaa tcgtcgaacg ccaggataaa cgttatattt atgtcaatct
    10561 tggtaaaatt gaggcagttc tttctaaaca agatcaaatg ccaaatgaat tttatcaacc
    10621 acatgatcga atcaaagttt atgtttcccg agtagaaaat acgtctaaag gtccgcaagt
    10681 atttgttagc cgcagccatc cagacctatt gcgccgctta tttgagcaag aagtaccaga
    10741 agtctatgat ggaatcgttg aaattgtcag catcgcccgt gaagctggcg atcgttcaaa
    10801 agtggcagtt cgctcaaatg atccaaatat cgatgcagtc ggtacatgtg tcgggccaaa
    10861 gggacaacga gttcaagcaa tcgtcaatga attaaaaggc gaaaacatgg atatcgtcga
    10921 atggaatgaa gatccagctg tattcattgc aaatgcattg aatcctgcac aagtcatgga
    10981 tgtgatcttc gatgagacaa atccaaaggc ctgcacagtt gtcgttccag actaccaatt
    11041 atcgctagca atcggtaaac gcggacaaaa cgcacgttta gctgctaaat tgactaacca
    11101 taaaatcgat atcaaatcag aatctgacat gacggaattt tatgaaaatc aagaacaaca
    11161 aaaagaaaca gaagaactgc atgatgaagc aatcgttcag tcagatttaa cagacgatga
    11221 atatgaaaca attgcattca acaatgaaac ggtcgaagaa aaaccagaag cttaacttta
    11281 gtaaggaggc aaagagatga aacaaaggaa aattccttta cgcaaatccg tggtttcagg
    11341 tgaaatgaaa cctaaaaaag agatggtccg aatcacccgt tcaaaagaag gggaagtatc
    11401 gatcgatcca actggaaaaa tgcctggacg aggagcgtat gtctcacttg agccggaaga
    11461 agtacaacaa gcttgggata aaaaaattct cgatcgagta ctcgaaacaa cattaacaga
    11521 tgagttttat caagaacttc ttgactatgt cactcaccaa aaagcacgta aagagttatt
    11581 tggaaaatga atacagttaa tcggcaaaaa gccatgaatc tcatcggtct agcgatgcgc
    11641 gcgggaaaac taatcacggg tgaagaactg accattgctg aaatccgcaa acaaaaagca
    11701 aaattggtgt ttgtggcaac cgatgcaagc gagaatacaa gaaaaaagat aaaagataag
    11761 agttcatatt atgaagttcc ttgctttgag ctattttctg aagcagaaat cacgcagatg
    11821 atcggaaaac ctcgcaaggt attcggaata atggatgccg gatttgcgaa gaagaccaag
    11881 gagctaattg aaggttagga aggtgattgc atgggcaaca aaagaatcta tgaattagca
    11941 aaagaactca aaaaatctag taaagacgtc gtggaaaaag cacaacaact tggcatcgat
    12001 gtgaaaaacc atatgggtgc gattactagc aatgatgaga agaaattgca acaagcgttc
    12061 aaaaacccaa gcacgaaaca acaagctgca caacaagcaa gcagaaaacc agccaatcaa
    12121 cagccgaacg atcaacgtaa aaaagaaaca acgaacaatc aacaaaaaaa taaaaataac
    12181 cgcagttatc aagatcgcgg tcaagggagc ggtcaagtga atcaaggaaa aaaaccaaca
    12241 acaaaccaaa ataatacggg aaataccagc agccaaaatc gtcaaggaac gagccaaggc
    12301 ggcaatcaaa accgtactaa caataacaac aaaccaaaca ataacaatcg cggcaaattt
    12361 aataataata accgtaatcg ttataataaa aaaggtaaaa aaggcaaaca gcaacaatca
    12421 actaaaccag ctgtaccacc acgcaaattc cgtgaattgc cagatgtatt agagtatact
    12481 gaaggtatga acgtagcaga tattgcgaaa aaaattcatc gtgagccagc agaaatcatt
    12541 aaaaaattat ttatgcttgg tgtcatggtc aatcaaaacc aagcactgga taaagatacg
    12601 attgaactgt tagcgacgga ctatggcatg gaaccacaag aaaaagtcca agttgacatt
    12661 gctgatatcg ataaattctt cgaggcagaa gaagtcgatc cagataaatt agtctcacgt
    12721 ccgccagtcg taacgattat gggacacgta gaccatggga aaacaacttt attggataca
    12781 ttacgccatt cacgtgtaac aagcggcgaa gccggcggaa tcacacagca tatcggtgcc
    12841 taccagatcg atattgatgg taaaccaatc actttcttgg atacaccagg acatgcggcc
    12901 tttacaagta tgcgtgcacg tggagcaagt atcacagata tcacgatctt agttgttgct
    12961 gcagatgatg gcgtcatgcc acaaacagtt gaagcaatca accatgccaa agctgcaggc
    13021 gttccaatca tcgtcgctgt aaataaaatt gataaaccag gtgcaaaccc tcaacatgtt
    13081 atgcaagaat taagtgagta tgagttaatt cctgaagcat ggggtggaga aacgatcttt
    13141 gttgagatct cagcgaaatt cggccaaaac atcgaagaat tgctggaaat gatcctgtta
    13201 gtcgcagaag tagaagattt aaaagcagat ccaacacaac gcgcaatcgg aacagtgatc
    13261 gaagcacgtc ttgataaagg taaaggtcct gtgtcaacct tacttgtcca agaaggaaca
    13321 cttcatgttg gtgacccaat cgttgtcggt aatacttacg gacgtgtccg tgtaatgaca
    13381 aacgatcttg gccgtcgcga taaagaagca ggacctgcaa cgccagtaga aatcactggc
    13441 ttgaatgatg tacctcaagc aggtgaccgt ttcgtagtct tcgaagacga aaagacagca
    13501 cgtgcagcgg gtgaagaacg cgcgaaacgt gcattattag aaaaccgtgc tgccacaagc
    13561 cgtgtgactt tggataactt atttgaaagc ctgaaagaag gcgaattgaa agaagttaac
    13621 gtaatcatca aagcagatgt acaaggttca gcagaagcac tggctgcatc attgaagaag
    13681 attgatgtgg aaggtgtccg tgtaaaaatc gtccattcag ctgtcggagc aatcaatgaa
    13741 agtgatgtaa ccttagcagc agccagcaac gctattatca tcggtttcaa cgttcgtcct
    13801 acaccgcagg caaaagtgca agctgatact gaagaagtcg atattcgtct tcaccgtatc
    13861 atctataaag ccatcgaaga aatcgaaact gcgatgaaag ggatgctaga ccctgaattt
    13921 gaagaaaaaa tcaccggtca aatgatcgtt cgtgaaacct tcaaagtttc taaagttggt
    13981 acgattgcag gtgcctatgt aacagaagga tatattcgta gagatagcgg tgtccgtgta
    14041 atccgtgacg gaatcgtaat ctatgaaggc caacttgcaa gtctgaaacg attcaaagat
    14101 gacgtgaaag aagtcaaaat gggttatgaa tgtggtgcaa tgattgaaaa attcaatgac
    14161 atcaaagtag atgacgtaat tgaaggattt atcatggaag aagtcaaaaa tgactaaaaa
    14221 ctgataaaag gaggccaatc attatggcta actaccgtga ccgccgagtc ggtcaagaaa
    14281 tcttaaaaga agtcaatgat attttgcgca aaaaggtccg tgaccctcgt gtggagaacg
    14341 taacgatcac agatgtgaaa gttacggggg acttacagca agcaacgatc tattacagca
    14401 ttttatctga cttagcatca gataagaaaa cagcacaaga tggattgaat aaagcatcag
    14461 gattgattcg tcgagagtta gggcacaatc taagtattta taagacacct gaattgttct
    14521 ttgaacttga tgaatcagtt gtctatggca accatatcga tgaattgctt cgcgacttga
    14581 acaaagacta atcaaaaact cccgcaaatc ctgtgaaatc aggggttgcg ggattttttt
    14641 gttttcatta agacgtatta cctaagagtt ccatgacttt agtcttgcgg cgtgtcagct
    14701 aaccaaaaaa gagaaaaaga aaagtaaaaa attcgacttt cttttttcta gtagtatata
    14761 aatttttgca tatagataaa gatcaagata ccgataacgg aagctagatt gtaatctatt
    14821 ttagtgacag tcaggtatag ccaagtaact agaagatcag tggaacctgc accataaaag
    14881 tttgagtttg tcggtccgtt gacagttaaa agaaaaatca cgttgaagtt attgatattt
    14941 ccgattacgc cgcttcgatt tggtcacgat ccaaattttg gataatccct gtagaaatta
    15001 gcatagtagc tgggatacca attcacatat tgacaaagat aacagagact tttacataaa
    15061 acggatcaat caggaaagga attgctcgat ccagccccag ttttccagca atgtgttaac
    15121 tggcccagcg tcattcagca aattatgcat gatgaggagc gaaatgaact gcggaacagc
    15181 cattgtgata acgacaagtt ttttggatca atgtaaaaaa cgtcagcgaa aggaaaaatt
    15241 tcgtggtttt ttatacctgt tcatttggct agatataaaa tccaaacaaa tgaacagaag
    15301 tgcttattag gtttcaattg ggagtatctg cgctagaata agagtaataa tgaaaaggag
    15361 tgttatgtat ggattattct agtaaagaat actttgataa aatgacggct tggtggcgtg
    15421 ctgctaatta tctttctgtt gggcaacttt atcttaaaga taacccctta ctgagacgta
    15481 cactgaaacc cgaagatgtc aaaaaacatc caatcggtca ttggggaacg attcctggcc
    15541 aaaattttat ttatgtccat ttgaaccgag tcatcaataa atatgatttg aacatgtttt
    15601 atattgaagg gccaggacac ggcggacaag tcatggtatc gaatgcttat ttagatggaa
    15661 gttacacaga gatctatcca gaagtaacgg aagatgagac aggaatgcaa aaattattca
    15721 aacgattttc atttcctgga ggcattgctt ctcatgcagc accagaaaca ccaggttcta
    15781 tccatgaagg cggagagctt ggatactctc tttcacatgc agtcggagct gtattagaca
    15841 atcctgaagt aatctctgct gtcgtgattg gtgatggtga agcagaaacc ggtcctttag
    15901 ctggaagctg gttctcaaat gtctttatca atccagtgat agatggagct gttttaccga
    15961 tccttcattt aaatggtgca aaaatagcca acccaacgat cttggcacgt aaatcagatg
    16021 gagaattagc aaattacttt aacggacttg gctgggaacc tttctttatt gaaggaaatg
    16081 attcagaaaa attaaatcct gttatggctg aaaaaatgga tcaagcaatc gagaaaatta
    16141 aatccatcca aaaagaagct cgcctgaaga cagcaacaga tgtcgtgatg ccaaaatggc
    16201 cagtattgat cgtacgcaca ccaaaaggat ggaccggtcc aaaagaatgg gacggggaac
    16261 caattgaagg aaccttccga gcacaccaag taccgattcc tgtagatcaa gaacatatgg
    16321 atcatgcaga tgctttactc cgttggctga aatcctatga accagaaaaa ttatttgatg
    16381 cacaaggacg tattttagaa gaaatcagag aaatcgcgcc tactggtgac caaagaatgg
    16441 caaaaaatcc tatcaccaat ggtggaatcg atccaagacc gcttattatg ccagattgga
    16501 aaaaatatac tttgcaattt gaaaaaccag gctccgttaa agcagaagat atgaccgaac
    16561 ttggtaaatt cgttcgcgag atcattgaga aaaatccaga aaatttccgt atatttggac
    16621 cagatgaaac aaaatcaaac cgattgaatc aagttttcaa aacgacaaat cgccaatgga
    16681 tggaaaaaat cgaaccagaa aatgatgaat ggctttcgcc atctggtcgc gtcatcgaca
    16741 gtcaattatc ggaacaccaa gatgaagggt tcttagaagg gtacgttctg actggacggc
    16801 atggtttttt gcaagttacg aatcattctt gcgagtggtt gactctatgt tgactcagca
    16861 cttcaaatgg atgcggaaat cacatgacct ttcttggcga aatgattatc cttcgctaaa
    16921 tctcattgca agctcaacag tcttccagca agatcacaat ggatatagcc accaagatcc
    16981 aggaatattg acacatttgg cagaaaagaa ggcggagttc atccgtgaat atctgcctgc
    17041 ggatgcaaat acattgctcg cagtcatgga taaagcattc cgctcgtcag aaaaaatcaa
    17101 tttgatcatc tcttccaaac atccgcgtgc tcaattttac tcagcagaag aagcagccgt
    17161 cttagtgaat gaaggcttga aaatcattga ttgggcttcg acagcaaaag aggaggaacc
    17221 tgaattggtc attgctgctg caggaacgga atctaactta gaagcattag cagctgtaac
    17281 tttgctgctg gaagaattcc caaaactaaa aattcggttc atcaatgtcg tagatttatt
    17341 gaaattacgt catccaagtc aagatccgcg tgggttgagc gatgaagaat ttgatcaata
    17401 ttttacaaaa gacaaaccga tcttatttgc tttccacggt tatgaaacat tggtccgcac
    17461 gattttcttt gatcgtcata accatcattt aatgattcat ggctacaaag aaaatggaga
    17521 tatcacgaca ccatttgaca tgcgtgtagt aaatgaactt gatcgttatc atttggcaaa
    17581 agacgcagct ttaaaaatca aaggaagtca agcagaagat tttgcgaaaa aaatggatca
    17641 gaaattacaa gaacatcaaa actatattcg tgaaaatggt attgatctgc cagaagtatt
    17701 ggattggaaa tggaaaaatc ttgaccaata aaatgataaa atcgatcccg caaaatagaa
    17761 ttttttacat tgattaagaa actgaaaaaa taaataaaaa aaacggaaaa aagactggaa
    17821 gaatggccag tctttttttt cgtttttggg aagtgaaaac caaactattt acctgtaagc
    17881 cacccataaa tccaatcaaa tggtgcaaag aaaaaatctt ccattctatt ccctccttta
    17941 aaaaagcata acatgatttc tatttacgtg agcatgaatt ttgttacgtt tttattgccg
    18001 aaaaataaaa accgttcatt atgatgtcaa attcgtcagt aattgatgca atgtgttata
    18061 ataattcagt taaatcaaaa atgaaatgga gaaaagacat ggacgggtta ttacctttat
    18121 ggaaagaacg cggaatgaca agtcatgatt gcgtattcaa attaagaaaa atcttacata
    18181 cgaaaaaaat cggacatggg ggtacgcttg acccagacgt agacggtgtg ttgcccattt
    18241 gtattggaaa agccacaaaa gttatcgaat atttgacaga ttctgggaaa atctatgtag
    18301 gcgagataac tctaggtttc agtacaacga cggaagatcg atccggagaa cgggtagaaa
    18361 caaaaccagt agatatgtct ttatctgaaa aaaaaataga tgaagtgatg gcttcattta
    18421 ttggtgagat cacccagata ccaccaatgt actcagcggt aaaagtcaac ggtaagcggt
    18481 tatatgaata tgcccgcaat aatgaaacag tggagcgtcc tgttagaaag gctcagattt
    18541 accgttttat ccggacaagt gaattgacaa gagacgaagt gacaggaacc atttcttggc
    18601 gcttcgaagt agaatgcggg aaaggaacct atgtccgcac attagctgta gatacaggca
    18661 agaaacttgg ttaccctgcg cacatgtctg atctgacccg aacagcaagt gccggtatgt
    18721 cccagaagga tgctctgaca ttagaagaag tagctcaagc tgtgaaaaat gggacaatcg
    18781 atgattgttt gctgccaata gaaaaaggag tggaacggtt caaacgagta gatattactg
    18841 atgaagtatg gcagaaagta aaaaacggta tgagacttga ttatactgta tttgcgctcc
    18901 cagaaatgcc gtcagaagaa attgctttgt tttataaagg aaaagttgtc agtatttatc
    18961 agccaaaccc gaaagaaaaa aacaaattaa aacctagtaa agtattgaga aatgaggaat
    19021 aacgaatgaa tatcatcaag atcagacatc cttaccaatc agaacaaatt ccagaagacg
    19081 atgtcgtttt agtgctggga tttttcgacg gcgtgcatat cggacaccag aaagtcataa
    19141 agacaggtat ggaaattgca caaaaagaag gattgaaatt agcattgatg actttcaatc
    19201 agcatccatc tattgtcttt aaaaagatcg atcctagcag cgtgaaatat ttgactagcc
    19261 ttaagcaaaa agaagaaaaa atggccgctt tgggtataga ttatttatat gaagttgatt
    19321 ttacttcttc ttttgctcat ttagcaccgc aggaatttgt tgatcaatac atcgtagggt
    19381 tacatgcaaa atatgctgtt tccggttttg attatacgta tggaccaaaa gacattgcag
    19441 atgtcgctca ttttcctgaa tatgccaaag gaagattcaa aatcgtcaca gtttctaaag
    19501 aagaagaaca aggtgaaaaa atcagctcta cccgtattcg tggattacta gacagcggac
    19561 aagtaaaaga agcagcaaaa ctattaggtt gcacatatga ggtagaaggg gtagttgtcc
    19621 atggcgatgc acgaggcaga ctactaggat tccctacagc aaatgtcaaa gtaaagagca
    19681 cggttcattt gcctaaagaa ggtgtttatg tgtcggaaat aaaaattggg gaaacatggt
    19741 atccagccat gggttcaatt ggacataatg atacattcgg tgaaggacgg gagctgactg
    19801 tagagttgta tattttggac tttaatcaag atatctatgg tgaacatgtc gcggtacgct
    19861 ggaatcaatt tttaagagat caagtgaaat tttctagtgt agaggaattg attgaacaac
    19921 tcaaggagga tgaacaagca acagctgaat atttttctca gcaataaaac attatgcata
    19981 aaatctcttg tttatgtata actagcaatt acaataaaat gggtgataaa taagcccagg
    20041 aaaggggctg tgacaaaagt cttgtcacag cctttttttc caaataaatg gtttttcaga
    20101 agtagcttct tcggaaataa gccgaaattt cttgaagctg accacttctg tcacaacctc
    20161 tttctttata gaaataaaag gacactagca attcatgaaa acgattgcta gagcgtatca
    20221 tttgctttag actatatatc ttggtgtaca ctcactttaa ggcggaaata aaagttatcc
    20281 gtaataacag gtttaggtat gaaaaaggag tgggtactat gtacaaggaa ttagaaaaca
    20341 aagtcgcagt agtaactggt ggctcaaagg ggattggaac agcgattgct caacgattcg
    20401 ggaaagaaaa aatgaatgta gttgtcaact ataactcgga taaagaagga gcagaaaaag
    20461 cagtcaaagc aatcgaagag gcaggcggaa aagcagtctc tgtacaagca gatgtcagtt
    20521 ctgaagaagg aatacagcgt ttacttgata cggctttaga aaattttggg acactggacg
    20581 tttgggttaa taatgctggg atggaaaatc agcatccaac ccatgaactt agccttgaag
    20641 attgggaaag agtgttaaaa gtcaatttga ctggcgtttt tatcggaacg aaagcggctt
    20701 taaattactt tacagagaat aataaaaaag gaaatatcat caatatgtct tctgttcatg
    20761 aacagatccc atggccaacg tttgctcatt acgctgcttc aaaaggcggg gtaaaattat
    20821 ttaccgaaac ggtagcaatg gagtatgcac cgaagggaat cagaatcaat agtataggcc
    20881 ctggtgctat ccgtacacct attaatgcgg caaaatttga tgatcctgaa caaaaagaac
    20941 tcttggaaag tatgatccca ctaggacgcg taggtgaacc aaaagaaata gcggcgacag
    21001 ctgcatggtt ggcttcagac gaatccagtt atgttacagg tattacacta tttgcagatg
    21061 gtgggatgac tttatatcct tctttccaag gtggaaaagg ataagggtga ataaaaatgg
    21121 gtttattgat tgcattgatc ccggcagttg gctgggggat ccagccactg attttgaaaa
    21181 agattggtgg cagaccaaca aatgagatat taggaactgg tattggagcg gtgcttgtcg
    21241 gcttactcgt tcaattattc gcttctccag ctggtatttc agtgactaca tttttgatta
    21301 gtttactttc tggtgcattt tgggttattg gacaaacagg acagtataca tctttcaact
    21361 tgattggtgt ttctaaaacg atgccaattt cgactgcatt acagttagtc ggaacctcgt
    21421 tgattggtgt cttcgctttt ggagaatggt ctggaagtat ggggaaaatc attggagcag
    21481 cagcaatcat tcttcttgta tttggttctg ctttaacggc aatcagtgat gatcctggaa
    21541 aaaaaggcgg tatcacaaaa ggaattagtc tattagcatc aacaagtatt ggttattggg
    21601 tatacagtgc attgcctaaa ctagttgatg caagcggact ttccattttc tttccgcaaa
    21661 tgatcggtgt ctttttaggg gcagtgattt atgtgatttt ccgtaaacca accgcatttt
    21721 ctgaagacaa gagttggaaa gcaacgatcg ttggagccat ctttagtgtg tcagcattgg
    21781 cttatatttt ttcagcaaat gaaaatgggg ttgctactgc atatatcatt acacagctaa
    21841 acgtagttat ctctacatta ggcggtatgt acatcctgca tgaaaataag acaccaaaag
    21901 aaaaaaaatt aacgattatc ggattattgc tgatcgtagt aggaagcatg gtcacggtct
    21961 ttatttgagg ataaagatgg taaaatttca tttattaaaa aaatatttgt ttgaaccaaa
    22021 cagtaagtac ttataaaaaa atagcgctag aatttccaac atctctggaa tttctagcgc
    22081 tttttaattg tttaagatac aagggaaata tctgtctgga tcaataattt ttcattgatc
    22141 cattgactaa agtttacgac ataattgaag ttaccaccga ttagtatctc cgcatgattg
    22201 tctttataaa gatcgtattg taaaagacgg tcttttttat ttgcgtaaac atcgttatgg
    22261 tactggacta attgttctcg gaattgattg attgctgtaa aatcacgata ttgaaggttg
    22321 aaacgcatcg tgattggtgc atttagcatg aatcgctgca tttcttttgc tgcttcctct
    22381 gcttgatctc cgtataggaa ctcaaaaaga ttacgttcag aaaatttcca ttgcccgcca
    22441 acctttgttc cttttagttt tccttcatga agataatttc tgatagaacg tgtagtaaca
    22501 cctaattgtt cggctaattc atttactgag taaaaatctt tcaatgttca ccctcctatg
    22561 tgaatggttc tactgactta gttgatattt gcttaatcac gaaatgtaga aagaacgatt
    22621 ttaattaagg tcattgtaaa aatcaagtca gaaaattcta acttttattt ctctaaagaa
    22681 attcgttctc tcctaaagtg atattatatt taaatatacc tgaaaataat gggcagtatt
    22741 atgaaagatc actgatattt tctcgtattt tttccttatt caaaagtttt gcaggaaaat
    22801 tgctgaaaaa ataattttac tatgtagaaa attcaaagcc attcaatcag tgattttttt
    22861 cagcacaaga aagactcctt ataaaaatag cagatacttt gtcaattaag tgtttaacca
    22921 gggatgataa aaaggatagg attgaacaaa acctgtataa ggtgatgaat agtttcctcg
    22981 ccagtaaaag gtttattcgt ataaagcttt atcgccaaaa tttatcatga ccttttttat
    23041 cttcaatatt aaatgaaatc aattgttcaa tcaattccca gttgattaca cttttccaag
    23101 gaactttgat gacgttatcc gtatatacgt agcctgcttc ttggatattt ttttcaaggg
    23161 cacgaatcgc tgctttttcc ggtgcgatag aaaaatgatt tttagcaaaa ctaaatgcaa
    23221 taataaaggt accatggtca gtaaacatag gttggttcca ttttacagtt gtgtctagct
    23281 ggggatacgt ttctgttatc ttagcaaaaa ggtctttgat cttttgttga tgttcttttt
    23341 ctttgatttg attgatgatc ggctgaaatt tttccattct aaaacgcctc cattaagtgg
    23401 tttgatttat tttaccagaa aaacaatagt tatgtataaa aaacgaacaa aacacaagta
    23461 atgttgtaac cgctatattt atatgataag atgtctcaaa taataaaata gaaaagagac
    23521 ataaaaatga ttgacttggc aa
//
LOCUS       DAFTHM010000035        23261 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFTHM010000035 DAFTHM010000000
VERSION     DAFTHM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.035"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="L7C88_001371"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="L7C88_001371"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBP9558208.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="L7C88_001372"
     CDS             complement(1172..1867)
                     /locus_tag="L7C88_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBP9558209.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="L7C88_001373"
     CDS             complement(1880..2596)
                     /locus_tag="L7C88_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBP9558210.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3534
                     /locus_tag="L7C88_001374"
     CDS             2926..3534
                     /locus_tag="L7C88_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBP9558211.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="L7C88_001375"
     CDS             3859..4182
                     /locus_tag="L7C88_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBP9558212.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="L7C88_001376"
     CDS             4364..5734
                     /locus_tag="L7C88_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBP9558213.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="L7C88_001377"
     CDS             complement(5864..7165)
                     /locus_tag="L7C88_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBP9558214.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7519..9477)
                     /locus_tag="L7C88_001378"
     CDS             complement(7519..9477)
                     /locus_tag="L7C88_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBP9558215.1"
                     /translation="MTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9654..9920)
                     /locus_tag="L7C88_001379"
     CDS             complement(9654..9920)
                     /locus_tag="L7C88_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBP9558216.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="L7C88_001380"
     CDS             complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="L7C88_001380"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBP9558217.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="L7C88_001381"
     CDS             complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="L7C88_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBP9558218.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13264..13827
                     /locus_tag="L7C88_001382"
     CDS             13264..13827
                     /locus_tag="L7C88_001382"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBP9558219.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14080..14601)
                     /locus_tag="L7C88_001383"
     CDS             complement(14080..14601)
                     /locus_tag="L7C88_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBP9558220.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14604..15446)
                     /locus_tag="L7C88_001384"
     CDS             complement(14604..15446)
                     /locus_tag="L7C88_001384"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBP9558221.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15439..16164)
                     /locus_tag="L7C88_001385"
     CDS             complement(15439..16164)
                     /locus_tag="L7C88_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBP9558222.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16340..16636
                     /locus_tag="L7C88_001386"
     CDS             16340..16636
                     /locus_tag="L7C88_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558223.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17204..18796
                     /locus_tag="L7C88_001387"
     CDS             17204..18796
                     /locus_tag="L7C88_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBP9558224.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18809..19549
                     /locus_tag="L7C88_001388"
     CDS             18809..19549
                     /locus_tag="L7C88_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBP9558225.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19717..21066
                     /locus_tag="L7C88_001389"
     CDS             19717..21066
                     /locus_tag="L7C88_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9558226.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21194..21784)
                     /locus_tag="L7C88_001390"
     CDS             complement(21194..21784)
                     /locus_tag="L7C88_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBP9558227.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            22020..23099
                     /locus_tag="L7C88_001391"
     CDS             22020..23099
                     /locus_tag="L7C88_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9558228.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
BASE COUNT         6661 a         4820 c         4527 g         7253 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcaaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct gtttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gcttaccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa taatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaaaacggta ttcaaaagct tgcatctacg gcattaagcc
     7381 caaacagatg aaaaacatga gaagctgttt ttatctgctc gttcttactg cttgttgcag
     7441 tacagctttt tcatgacctc tgataaacgg tgttcaagta gctgacattc gacattagtt
     7501 caggtcaaag cgctactttc acaaccgctc tttcaaccat gttttccgag tatttccaat
     7561 gataagcgga acagtttcat gttttacttc gctgtactct agcccaaacc atgtttctgg
     7621 cgaggtagcg atttttttga ttgccagttt tgcctgcatg atttgacgtt gccattttcc
     7681 tagagttgtc acattggaaa ctacttcatc aatcaggaca aattggaaat cgccaacttc
     7741 tcgccctggt gtcagagagt atctttgtgg ctgttttggc aaacggcctt gtttcatcaa
     7801 atcatggatg acttggcgaa catatacgtt gatttcctgt tggaccctga aacctaagaa
     7861 cagattcact tggacaataa aatcagtgtc catcatatct acttgatatt ctttcgtata
     7921 tggctcatcc gtcacttcca catgaacaaa ccaatagact cgtgctcttt taggccgttt
     7981 atctaaaatc gaatagatga actgtcggcc aactttatct tcagccatat caggaaccaa
     8041 gaagaccaca tttgtctgat agattggtaa agaagtatca tcacgtaatt ctctaagctg
     8101 cgggatataa tctctcaaag acacatcctc ggttgacgat tcgcgaataa tgttcccttg
     8161 ttcccaaata aacatcacga ctaagatgat caaaccaatc agaacggcta caaaaccgcc
     8221 tcggaagaat ttgacaacac ttgagataaa gaaaacgact tctatcgcac cgaagaaaaa
     8281 ggtaactaaa tatgcaagcc aacgagaatg cccattttgg ataagataaa agtaaagcag
     8341 tgctgttgtc atcaacatcg tcacagtgat cgatagaccg taagcagctt ccatatgatg
     8401 agacgttcgg aatgtgacaa ccactagaga acaggcgatc cataaaatca gattgactgc
     8461 tgggatatac atttgcccga tactgttccc aggatacatg atctttaacc gaggcagcag
     8521 tttcaacttg attgcttctg aaactagcgt aaacgaacct gtaatcaatg cttgcgaagc
     8581 aatgactgca gcgactgttg caaaagcaac gccgatcacg atccaacttt gaggcatcat
     8641 ttggaagaat ggattcaggt tcttgatttg ctgtgcttca gggttttgat aaacattcaa
     8701 caaccacgca gcctgcccaa aataattgat aaccaaacaa attttgacgt aaggccagct
     8761 cagacgaata tttcgtttgc cgacatgtcc aagatcggaa taaagcgcct ctgcacctgt
     8821 cgtagccagg aaaatatttc caagaatgaa caagcctaat ttgttatctg cactaaaaag
     8881 cagctggata gcataataag gattcagtgc acggataact gtccagtctt gactgaagtt
     8941 cattaatccc attacgccta aaaaagtaaa ccaagcgaac atgattggtc cgaatgcttt
     9001 tccgacaata tctgtaccaa agcgttggac catgaataaa acaaaaataa taactaaagt
     9061 gataatgacg atcacgttct ggttattacc gaaccggtca aaaaactgcg gaattcctcg
     9121 caagccttca atcgcagtcg ttaccgtcac agcaggggtc aataccccat ctgctagtaa
     9181 ggcagctcct ccgatcattg caggaatgat caaatatttc ccaccttttc ggacaagtgt
     9241 gtagagtgag aaaattccac cttcaccatg gttatctgca ttcaatgcaa tcacgacata
     9301 tttgattgtt gtcagtagag tcaatgtcca aaaaatcaat gagactgatc cgataacaaa
     9361 atcaggattg attcctgaca atccgccatt atcttcaaca atcgatttca taacgtaaag
     9421 cggacttgtc ccgatgtctc cgtagacgac tcccatcgct acaagcaggc cagtcattga
     9481 tatctttttg gtattgtgcg ttgttgccac gtttttccct catttcttgt tatatggata
     9541 tcctttaggt aagcttgaat gatagatgat attcttatcc atgacacccg ctttcctaaa
     9601 ttgcttctaa ttatccaagt aacacactga agtgtcaact tatttgaata aaattattct
     9661 ttctttggac gttctctgat acgtcttgcc acaaatgaat aaagagcaag gcaaaaaatt
     9721 gcacccaata atgctggtat caaataaaaa ccgccgagtt ccggtcccag tggtcctagt
     9781 aaaaattcgc cgagccaact acctaaaaaa ccgataatga tatttccaga tacgcctccc
     9841 gggacttcct ttcctaaaat tgcgccagct atcaaaccta atataccgcc gataaataac
     9901 gaccataaaa aattcagcat ctcctttccc tcctttatcc atatttctca cttttatttt
     9961 acgctttatt cagaaggact ccaaaaatat gcgccaagaa actccagaaa aaaagaagtt
    10021 gtaacaaaag tgttcagctt atttccgtag aagctgcttc tggaacaccg tgaatcagag
    10081 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    10141 tattttgccg ttttttgagc taatatcgag ggacagctga ttgaacatcg tttattggag
    10201 aggttgtaaa aaagctgttc tgcatcaagt aataagaaca gccaaataaa aacagctcct
    10261 aatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10321 cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc cttttttcga ataattattg
    10381 tccccctgtc accttcacga tcacaagtac attattccta tgaattaaat tatttttctt
    10441 catttttcgt tgaaccatct tcgttcaaca ttgcttttct tgacagattt acgcgtcctt
    10501 gtttatcgat ttcagttact ttcacaagga tctcatcacc tagtttaaca acatcttcga
    10561 ctttattgac acgatcgttt gctaattggg aaatatggac aagtccatct tttcctttga
    10621 tcaagttgac gaatgcaccg aatttttcga tacggacaac tttccctaga taaacttcac
    10681 caactttgac ttctttggtc aaatcttcga tgatcttgat agcttttttg atcatttctg
    10741 catcagctga agcaatactt acttttccat cttgatcgat atcgattttc acaccagttt
    10801 catcgatgat tccgttgatc gtatcgccgc ctttaccgat aacatctttg attttagcag
    10861 gttcgatctg gatcatttcg atttttggtg catattggct taattcttca cgtggagcag
    10921 caatcgttga agtcaattct tctaagattt ccatacgtgc ttgttttgct tgagttaatg
    10981 cttcagttag gatttgttct gtgattcctt gaatcttgat atccatctgt aaagcagtga
    11041 taccatcttt tgtaccggca actttaaagt ccatatcgcc aagatgatct tccagccctt
    11101 ggatatcagt taggatcgta tagttttcac catcagaaac aagtcccatc gcaataccgg
    11161 cgactggcgc tttgattggt acacctgcat ccatcaatgc taatgtgcca gcacagatac
    11221 ttgcttggga agaagaacca tttgattcca atacttctgc tactaaacgg atcgtataag
    11281 gaaattcttc ttctgaaggg attacttgtg ctaacgcacg ttcacctaat gcgccatgtc
    11341 cgatttcccg acgccctgga gagcctgcac gtcctgtaga accaacagaa aattgaggga
    11401 aattgtagtg gtggatgaat cgtttgctga cttccacccc taaaccatca atgatttggt
    11461 gctctcctag aggtgcgagt gtacaagctg ataaagcttg tgtttgtcct cgtgtgaaca
    11521 aacctgatcc atgtacacgt ggcaataagc tgacctctga tgacaatgga cggatttcat
    11581 ccaatttacg cccgtcagga cggatcttat cgatggtgat caattcacgt acgacatctt
    11641 tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa gtgatcttca tcttcatgac
    11701 ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt cacctgctcg atattatctt
    11761 cgcgagcaag tttttcttca gtcattactg ctgctttcat tgtagcgtaa gaagcatcaa
    11821 agatttcttt tttcaatact tcatcaactt gcagtaaagt cacttccatt ttttctttcc
    11881 ctactgcttg aacgatttct tcttggaaag caactaactc tttgatagcg tcaaaaccaa
    11941 acagcaatgc accaagcatg tcttcttctg aaacttcttt cgcgccgctt tcaaccatat
    12001 tgatggcttg tttcgttccg gcaacagtca attcgatatc tgtttgttct gcttgttcta
    12061 ctgttggatt caagacgtac tcgccattta cacgaccaac ttctacgcct gcgattgggc
    12121 cgtcaaatgg gatatctgag attgatagtg ctaaagaaga acctagcatt gctgccatag
    12181 ctggcgagca gtctgtttct acactcatca cgatgttcgt tacttggact tcattacgga
    12241 agccttctgc aaacatcggg cgaattggac ggtcgatcaa acgggcagtc aatgttgctt
    12301 ccgtacttgg acggccttct cgtttgatga aacctccagg gattttccct gctgcataca
    12361 ttttttcttc ataattgatc gttaatggga aaaagtctgt atcttttgct tctttagagg
    12421 ccacagctgc acttaagact actgtatctc cataacggac taaaacggct ccgtttgctt
    12481 gttttgctag ctgaccgact tcgatttgta agggacggcc gccccatgtc gttttgaata
    12541 cttgtttttc tgacataact tctccttttc cttctcgtga aagcaagacg ctactaaaca
    12601 aatgaaaact gccgaaagcc gtcttttgag cagctttcat ttggttagta ggagtccatc
    12661 tagcttgatc acggaatttt acttaattga tatacgagta aaaaaagtga gattcatgtg
    12721 aatcccactc tttttgacta aaattaacga cgcaagccta aacgtttgat caattcgcgg
    12781 taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt tacggcggtg accaactttt
    12841 ttcattaggc cgcggtatga atgatggtct tttttgtgca cgcgtgcatg ttcattcaag
    12901 tggttgattt cttcagttaa tacagcgatt tgtacttctg gagaaccagt atccccttca
    12961 tggcgagcgt attcgttgat gatttcattc ttgcgttctt ttgaaattgc catttctttc
    13021 acctctttcg attattcccc tgcgactgag taaaacgttg gtgattcgct taaccaagtg
    13081 gcaggtcatg tgcctagagc acacagctat actttacctg aaaccgggtt gaaaatcaag
    13141 tagttaatca ttaagaaaag gtagttttca aacaatctta ctactacttt tccatttttg
    13201 tggtaaacta taatgcgaaa atagacttga aacacagtct tttaagaaag gggtacatat
    13261 tccatgatta caatggatga tatcattcgt gaaggaaatc cgaccttacg cgaagttgca
    13321 aaagaagttt ctcttccatt aagcgaagaa gatatctctt taggaaaaga gatgcttgag
    13381 ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac tacacttacg aggcggtgtt
    13441 ggcttagctg ctcctcaatt agatatttct aaaagaatca ttgctgttca cgtaccaagt
    13501 cctgacccag aggcagatgg accttctcta agtactgtta tgtataatcc taaaattttg
    13561 agccattctg ttcaagatgc ttgtttaggg gaaggtgaag gctgtttatc tgttgatcga
    13621 gaagtaccag gatatgttgt tcgccatgcc aaaatcactg tgtcttatta tgatatgaat
    13681 ggtgaaaaac acaagattcg tttgaagaat tatgaatcga tcgtcgttca acatgaaatc
    13741 gaccatatca acggtgtgat gttctatgac cacatcaacg atcaaaatcc atttgcacta
    13801 aaagaaggcg tattggtgat cgagtagaga attggcaggt tccttcgata ctatgctaca
    13861 agaaagcttt ataaaaaagg ggagtgctca aaagctgcac ttcccttttt tatgtttctc
    13921 cactaatcga aatttagata gacatctaga aatcgcaatt ccaaaaaatt ctgtgtattg
    13981 gatacgcatc ttttcttatt ttttcttatt tcttccatat gggtgtttat ctcagagatg
    14041 atagaatagt ttctaggata aaaagtagca gctacgatgt tatccttcgt agaggattcc
    14101 tgcttcagct agtttttgtt tgatgttttt cagcatatgc ttttctgggt agcggatcgt
    14161 atgcagatgg atgccgcctg ttaattcgga taacaaagta gcattacttt tttgataacg
    14221 tctcataaag gaatcgatat cttgtggcgt tttgatgtgc aaagttcctg ctaactcacc
    14281 gtaaagggga tgttccacaa ttacatcaat gatttcacca ccattttcaa cgattagtct
    14341 cagttcttct tctgtttgat cttttccatg ctggacagcg attttactga tgtgcccagt
    14401 attggtttct tctgtttcga ggatataacc tcttgctgtt gccacgatac ttttacctgc
    14461 agctcgtagt aaagcaatat cgcctacaat gatctgacgg ctgactccaa aagttttcgc
    14521 aaacttgcta gcactcactg gtttttctgt atttgccaag gtttgcatga tttgttttcg
    14581 ccgtgtctct ccttcgatca cacttattcc tccttcattt tgttttggta ttcgcgcgag
    14641 tgtttcatca aatcaacata cgtgtctgtt attgtttcct tatatccctt atttttcagc
    14701 agactaacaa ctttatccaa tacttgctgc tctctttttg catcataaac tgcttggttt
    14761 tcttcttttt tcacttgtcc tattttagtt accgtatcca ttcttttttc taataaagca
    14821 accaactctc gatcgatcat atcgatctta tgacgtaatg tttcaagaga ctcttctgtt
    14881 agttcttcct ctactgtctt gatgatacga gcaggatttc ctgcaatcac tacattgtcg
    14941 ggaaaagatt tggtcacaac cgaacctgcg ccgactacta cgttgtcccc tagagtgaca
    15001 cccggcgtga cgataactcc tccgcctaac caaacattat taccgatttt aatgggtttt
    15061 gcgtactcca gaccgctgtt acgtttcact ggatgtagtg gatgcgtcgc cgtgtaaagc
    15121 tggacattcg gagcgaacat gcagttatca ccgatttcaa tcgtgctgac atctaaaaat
    15181 gtacaattga aatttgcata aaaattctcc ccaacaaata tattatatcc gtaatcaaaa
    15241 ttgataactg gctccatata gatttttttc cctgtacggc caaaagtctc tttcaacaat
    15301 tgggatcgca gttccgctga ttctgcttgg ttgatgattt ggctttgact tcttgcaaac
    15361 atacggtcgg caaccagctc aggatcattg gcaaaataaa gctcgcctgc aatcattttt
    15421 tctttttcgg ttttgaattc agtcataatc tgctcctaat tcttgtattt ttttgaaaac
    15481 aaccgctccg tcttcttgaa taaacgtata aggctccgct aaataaacag gcgtttgatt
    15541 gattactaag attttggctg acggctggcg aaactgtacc agatcacaaa acggatgaac
    15601 ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg ctgacggcat aagccgcctg
    15661 ctccatgact ccatcttgaa acccttcacc atataacacg atgtctgggc gtatttgtcc
    15721 tccgcatgct tgatgtttgt cgctgtgaag atattctttc cagtctaccg tttgttgaca
    15781 ttttcgacaa tgacattgat acagactccc atgaaaattg acgagttgcg ggcttttagc
    15841 ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa acattttttt ctttcgctag
    15901 atgtgctatt tccaaatgaa tgatattggg ttttgcttca ggatgataaa tctttttgac
    15961 aaattgatag aatttatccg gttcattcac cattgcttga tgactcagca agtattccgg
    16021 ctgctccatc ccgtggtaga ttcctgacaa agatcgatag tctggcactc cagaaggtgt
    16081 ggatacccct gcaccggtca aaaatgtaat ttgctgataa gctaatatct cttttgctgc
    16141 ttcgtctact gttaattgtt tcatgttttg tcacctcact ttccattata gcccatactc
    16201 gaacaaattt attgttgaaa agtcagaaaa atgggaataa aaaagtgtta tgggcatttg
    16261 agcaatttat cacaatgttc actgacaaaa gaatgaaaac gtgttacaat actgctgtat
    16321 aaaagtgagg tgaatcgata tgttaccatt ctttatttat tggggcgtta ttctggcttg
    16381 tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt tatcttgtac gcaaagaaaa
    16441 tggaaatctt tgggcttttg ctttattcaa cgtgattgcc gcaattgttt tagccattac
    16501 attagccgta tatcgaacat ggggctgggg aatcacccaa tactcaagtt tgatttatct
    16561 aatattagcc atttatggcg tcgttgttct tttgcaagcg atcctaggac gtgagccaaa
    16621 gaaagcggca gcttaaatga tcgagatgga actggacaca ggaaattttc tgttctagtt
    16681 ctttttttat tgtattacat acatttttgt gtataattat actatcgttt gcaatggata
    16741 gatgattcac attttgattg ttttttcggt aaaagtaaag atttctatat ttatcagtat
    16801 tttttcaaaa accagcagtt atagattgac aaagcctctc gagtatcgta aacttttttt
    16861 gtataaataa ctgaatacga gatgcctcaa tcaatgaggt agaggtcgcg agaatcatta
    16921 accctgtgga gtgaagcaaa catggagaag caggaatagg gaggatcgcc gaaatgtgca
    16981 cttttttgct tggagtgtat gttgggacgc aagttaagag cttgcggact gtcttagcag
    17041 tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac cttatggaat tttagcggcc
    17101 tttttatatc tataaatcgg tcgcttttta ttttttcaga taaagcttta ccgcatttca
    17161 tctagaccgc tcgtgtatca tataatcaga aagggagaaa aaaatgaaaa aaaatatggt
    17221 ttcagttgcc gtactatttg cttttgtctt ctcactattc agtgtgggat ctctggcaaa
    17281 tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt atggaggctg ggtatgcacc
    17341 cttcaactgg tctcaacaaa cagatgagaa taatgccttg ccaattcaag gccaaaatag
    17401 ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta gcagatggtt tagggaaaaa
    17461 attagtcatc gtccaaacga aatgggatgg tctggctcct gcccttcaat caggcaagat
    17521 cgacgcgatc atcgccggaa tgagccctac tgctgaacga cgaaaagaaa ttgattttac
    17581 cgatccttat tacgaatcac aattagtagt agtagttcaa aaagatagca aatatgcaaa
    17641 agcaaaaagt ttagcagatc tttctggagc aaagatcact gctcagttaa atacattcca
    17701 ctatactgtg atcgatcaga taccagatgt gcagaaacaa caagcaatgg ataatttctc
    17761 agcaatgaga acagctttag cttctggaat gatcgatggt tatgtcagcg aacgtccgga
    17821 aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg cttgaattca gcggtgcaga
    17881 tggcttccag acaaacccgg aagatgttca gatttctgtt ggtatgcgta aaggcgaccc
    17941 ggatatccaa aaagtaaacc agattctttc tggcatctct aacgatgaac gaaccaaaat
    18001 tatggaccaa gcagtcaaag atcagcctgc tgcaactgat agtgaagaaa aacctggcat
    18061 catttctgat ttcactacga tttggaaaca atacggcaat atgttcttac gaggtgctgg
    18121 acttaccttg ttcatcgcat tgatcgggac agttgtcggt actacacttg gattactgat
    18181 tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg actcgcttct tccaaaaaat
    18241 cggaaatgca cttctttcta tctatgtcga agtattccgc ggaacaccga tgatggtaca
    18301 agcaatggtc atcttctacg gtctggcact cgcttttggc atttcattga accgaacgat
    18361 tgccgctttg tttattgtct ctctcaatac tggagcttac atgacagaga tcgttcgtgg
    18421 ggggattttt gcagtagatg aagggcagtt cgaagctgcg caagccattg gtatgaccca
    18481 tggccaaacg atgagaaaag ttgttattcc acaagtttta cggaatatct tgccagcaac
    18541 aggaaatgag tttgttatca atatcaaaga tacagcagtt ttaagtgtaa tcggcgtagc
    18601 tgatttgttc ttccaaggaa actctgcttc cggtgcgaat ttccaattct tccaaacatt
    18661 tacgatcgtc gggatcatct acttagtcat gacctttacg atcaccagaa tcctgcgggc
    18721 ggtagaaaag aaaatcgatg gtccttcagc ttataccaag cttgaagaaa tcgacaattc
    18781 aaatttgcag gaataaggag gaagaatcat gaatgaaaaa attattgaaa tcaaacatct
    18841 aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc agcgtaacag tcaataaagg
    18901 tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa tctactttct tgcgctgtat
    18961 caatttactg gaaaaaccaa caggcggcga gatcatttat aatggagaaa atgtattagc
    19021 tcctaaatat aatttaccta aatatcgaac gaatctaggt atggttttcc aatccttcaa
    19081 cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct ggtcaaacaa ctgtcctgaa
    19141 acgagataaa gaaactgcca aaaaagtagc aatcgaaaat ctggaaaaag ttggtatgga
    19201 tcgttatatc gaagccaaac cagcacaatt atctggtgga cagaaacagc gtgtcgcaat
    19261 tgctcgggca ttatcaatga atccagatgt attgctattc gacgaaccta cttcggcgtt
    19321 agaccctgaa atggttggcg aagtgcttaa tacgatcaaa gacttagcac atactggctt
    19381 gacaatgctt atcgtgacgc atgagatgga atttgcaaaa gatgtatctg accgtgtcat
    19441 ttttatggat aaaggtgtga ttgcagaaga aggtacacca gaagatatct ttgtccatcc
    19501 gaaagaagaa cgtacaaaag aattcctttc acgtatttta aatgcttagg atcaatagct
    19561 gattgggaca aagagctgcg gtgtttaccg cagttctttt ttatgaatta ctcataaaag
    19621 gtaaatttct gaaaattttg gaatcttagt tgtgtttttc agaaaactct cttaatatgg
    19681 aagtaattaa acttttttag ttaggatgat ttaaaaatga atgaagagca agaactgcag
    19741 cgtggactga aaaatagaca tgtccaactg atttctattg gcggagcgat tggaacgggg
    19801 ttgtttttag gttccggaaa gtctatccag ctagctggcc cttcgatatt gctcgcctat
    19861 cttattactg gatgcatctg ttttttcatt atgcgtgcgt taggcgaact tctgttatca
    19921 aacaccaata accattcttt tctggatttt gttgcagaat atcttggcaa aaaagcggct
    19981 ttcatcactg gctggacgta ttggttctgc tgggtatcga ttgcaatggc cgatttaaca
    20041 gccatcggaa tgtatgtacg ctactgggcg cctggtgttc ctcagtggct tcctgaactg
    20101 attgcattag gtcttcttct ttgcttgaat atggtggctg tctcattgtt tggtgagtta
    20161 gagttttggt ttgcattgat caaagttgta gcgatcattg cctttatcct cgtaggagct
    20221 tatatgatcc tcacccacta tacgacagat attggcacag ccagtatcac gaatctatgg
    20281 tctcatggcg gattctttcc aactggtgca aaaggattta tcttagcttt ccaaatggta
    20341 acctttgctt ttgctgggat agaattagtt ggattagtcg ctggagaaac agaaaatcct
    20401 gaaaaagtgt tgccggaagc tatcaataat attcctatca ggatcatctt attttactta
    20461 ggatctcttt ttgtcattat ggcaatctat ccatggaaca gcttgaatcc agataacagt
    20521 ccatttgtag aagtattttc ggaaattggg atcacgattg ctgcttcctt gatcaattta
    20581 gtcgtattaa gtgcagcagc ttctgcctgc aacagtgcaa tatatagtac aggacgtatg
    20641 cttcgttctt tagcgcaaga aggcagtgcc cctaaaaaat tcaaaaagtt aacaacacat
    20701 catgtgccag ggaatgcttt gacattttct actatcgtca ttttcatttc tgttatcttg
    20761 aattacgtga tgcctagtga agtattcaca ctagtaagca gtattgccac tacttgtttc
    20821 ttgtttatct ggagtatgct tgtctacacg cacatgaaat atcgtaaaag tatcctcggc
    20881 aaaaaagctc attcatttaa aatgccgttg tacccattta gtaattatct ggtatttctt
    20941 tacatggcct ttgtgtgtgt cgtcttgttc ctaggaaaag atacgagaat cgctttatta
    21001 ctaacacctg tgtggttctt gcttctatta ctaatctatc atatgaaata tgaacgtaag
    21061 aagtaagaaa gtagttgtga cagaagtggt cagcttcgag aaataagaag gaatttacga
    21121 aaattgcttc ttaaattttt gtgaaatttc ggcttatttc ttggagataa aagcttctgt
    21181 cccagcctct tttctatttc cccggaaaca accgctgata ataggcatct gcttttttat
    21241 aggaaaaaat ccaaatacca gatacaaaaa aacgtccgaa taacccgatc aacggtacaa
    21301 aaaagacacc ggcaatcaag cataagttaa tcatcatgga gataagactt cgacggtcct
    21361 ttgacaaaac tctcacgaca tgggaatctg gtttatttgc tttcatgatt tgcctcatca
    21421 agataccaaa agaaaaactc cacatcgtgt atactaagac ataagccatc tcaggccaaa
    21481 aagcttcagg gttacgcccg acccaactag taacagaagg acataaagtc agccaaaaga
    21541 gcaaaaagat attcgaccag accactcggt aattaattcg ttctgccatc tgaaatatac
    21601 gatgatggtt cacccagatc accgcaacaa atataaagct gatggtataa gctaataatg
    21661 tatttcggat gacccataaa gaatgaaagc tagatgtatt agggatcttg atctctaata
    21721 caataactct caaaacaatg gctaccactc catcagtaaa tgcttctaat ctcgactttg
    21781 tcacgatgat tcctcctcag atgattcagc gcttttattt tatcacttac gttattaaat
    21841 aaccatcgtt ttatataggg aattttctga aaattgttgc atatttttcg aaattttgtt
    21901 acttttaaaa aaaggcggat tttataatta acttagccat ttggaaataa aaaaacgcca
    21961 cgtgaattcc atgttatatt gaagttacca caactctcaa tagacaagga tgaattcaca
    22021 tgacgcaaaa ccatgataac acagtttcac gcaagggaaa acacctaacc tactcagaac
    22081 gttgccaaat cgccatcctg aaaaaggaaa actattccaa ccgtcaggtt gcggatgtcc
    22141 tgggctgcgt gccgcagacc ataaacaacg aaatcaaacg cgggaccgtt actcagctta
    22201 accgccagaa tcagaacggg aaggtctacg actattatca tgacgtctac gacgccgatg
    22261 ccgggcaggc ggcctacgag aagaaccgct tgaactgcgg cagacggccc ttatgggccg
    22321 acacggacgc cttcattgaa tgggcggacg acatgatgct gttggaaaaa tggtccccgg
    22381 acgtggtggt gggctttgcc agaaaacacg aattgttcga cccggccatt atccctggga
    22441 ccaccaccct ctatcagtgg atcgaccgtg gcatcatgaa aacgaagaat atggacctgc
    22501 tagaaaaact gtcccgcaaa ccgaaatcgt cccgtcatgg caaccgcccg aataaacggg
    22561 tgctagggaa atccattgaa gagcgcccgg aggcggttgg tacccggaaa accttcggcc
    22621 attgggaagt cgacacggtc gtaggaaaca agaccaagtc ggatgccgtg ctgctgacgt
    22681 tggtggaacg gcagacacgc ttcgaggtca ttctgaagct ggccgggaag gatgccgaat
    22741 cggtcaacca agcggtccga cagctgagag aacgggctgg tgcgtacttc ggccagctgt
    22801 tcaagacggt tacctcggac aacggctcgg agttcgcggg actgcacgat gccttgcagg
    22861 atgtggcaaa catctacttc agccacccct atgcttcctg ggagcgcggg acgagcgaaa
    22921 accaacacaa gctgattcgc cgtttcatcc ccaagggcag cccaatcggc aacgtgagcg
    22981 aaaaccaaat cttgcggatt cagcgttgga tgaacgatta cccgcgaaag attttgggct
    23041 atgcaacgcc gcatgacacg ttcgtccagg catttaggca ggaacggttg acggcttgac
    23101 acgtgggccc ttgacaacga gcctccctcg gcatggcttg tgtctggaaa gctggccggg
    23161 gccagccagt cgggagacta ccatgcctca gctcattgtc aagggcccac tcgattagaa
    23221 aaattagacg gttggtggta acgagcaacc gggtcaccat g
//
LOCUS       DAFTHM010000036        22868 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFTHM010000036 DAFTHM010000000
VERSION     DAFTHM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.036"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(24..1520)
                     /gene="lysS"
                     /locus_tag="L7C88_001392"
     CDS             complement(24..1520)
                     /gene="lysS"
                     /locus_tag="L7C88_001392"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBP9558229.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1631..2635)
                     /gene="dusB"
                     /locus_tag="L7C88_001393"
     CDS             complement(1631..2635)
                     /gene="dusB"
                     /locus_tag="L7C88_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBP9558230.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2636..3523)
                     /gene="hslO"
                     /locus_tag="L7C88_001394"
     CDS             complement(2636..3523)
                     /gene="hslO"
                     /locus_tag="L7C88_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBP9558231.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3740..5851)
                     /gene="ftsH"
                     /locus_tag="L7C88_001395"
     CDS             complement(3740..5851)
                     /gene="ftsH"
                     /locus_tag="L7C88_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBP9558232.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5941..6486)
                     /gene="hpt"
                     /locus_tag="L7C88_001396"
     CDS             complement(5941..6486)
                     /gene="hpt"
                     /locus_tag="L7C88_001396"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBP9558233.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6486..7931)
                     /gene="tilS"
                     /locus_tag="L7C88_001397"
     CDS             complement(6486..7931)
                     /gene="tilS"
                     /locus_tag="L7C88_001397"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBP9558234.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8051..8521)
                     /locus_tag="L7C88_001398"
     CDS             complement(8051..8521)
                     /locus_tag="L7C88_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBP9558235.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8567..8992)
                     /locus_tag="L7C88_001399"
     CDS             complement(8567..8992)
                     /locus_tag="L7C88_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBP9558236.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9059..9328)
                     /locus_tag="L7C88_001400"
     CDS             complement(9059..9328)
                     /locus_tag="L7C88_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBP9558237.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9339..10934)
                     /locus_tag="L7C88_001401"
     CDS             complement(9339..10934)
                     /locus_tag="L7C88_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBP9558238.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10949..14470)
                     /gene="mfd"
                     /locus_tag="L7C88_001402"
     CDS             complement(10949..14470)
                     /gene="mfd"
                     /locus_tag="L7C88_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBP9558239.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14487..15047)
                     /locus_tag="L7C88_001403"
     CDS             complement(14487..15047)
                     /locus_tag="L7C88_001403"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBP9558240.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15400..16374
                     /locus_tag="L7C88_001404"
     CDS             15400..16374
                     /locus_tag="L7C88_001404"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBP9558241.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16544..17944
                     /locus_tag="L7C88_001405"
     CDS             16544..17944
                     /locus_tag="L7C88_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBP9558242.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18022..18744)
                     /locus_tag="L7C88_001406"
     CDS             complement(18022..18744)
                     /locus_tag="L7C88_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9558243.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18823..19329)
                     /locus_tag="L7C88_001407"
     CDS             complement(18823..19329)
                     /locus_tag="L7C88_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBP9558244.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19452..21251
                     /locus_tag="L7C88_001408"
     CDS             19452..21251
                     /locus_tag="L7C88_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBP9558245.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21319..22854)
                     /locus_tag="L7C88_001409"
     CDS             complement(21319..22854)
                     /locus_tag="L7C88_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBP9558246.1"
                     /translation="MTLTAVASPIAAAADDFDSQIQQQDQKIADLKNQQADAQSQIDA
                     LESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKREDTIQKQAREAQVSN
                     TSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKAVEDKKAENDAKLK
                     ELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLNRQKAEAEAEQARI
                     REQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSATEESSATQSSMTEE
                     SSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEESTTVPESSATEES
                     TTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTPEQPKPVTPAPAPS
                     GSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTGRDIGGWTVPQESA
                     GTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESVKVGSVQWFAPDFA
                     VSM"
BASE COUNT         6240 a         4979 c         4194 g         7455 t
ORIGIN      
        1 ttccttagac agcttttatt cgattatctc attgttggga atagcaaaac atcccgaatt
       61 gattgtgcat cagttagcaa cattactaat ctgtcgatcc cgatgcctag accaccagtt
      121 ggcggcatac cgtattctaa ggcttccaag aagtcttcgt ctacaccgtg agcttcgtca
      181 tttcctagtt cacgttcttt ttcttgcgct tcgaatcttt ctctttgatc aattggatcg
      241 ttcagttctg taaaggcatt agcaaattcg cgccccacta tgaatagttc gaatcgatct
      301 gtgaatcgag gatcttctgg atttttcttc gctaaaggcg aaacttcgac tggatgtccg
      361 tatacaaacg tcggttgtgt caatgtttct tcaacaaatg tttcaaagaa ttcattgata
      421 acatgtccga cacccatagc ttcggttact tctacattgt gtttttcggc taaagctaat
      481 gcttcttcca atgtcatttc ttgccagaag tctacaccag tttgttcttt gattgcatct
      541 accatatgga tgcgtttaaa gtcactttct aagtcgacag cttgtccatc atatgtgatt
      601 tttgctgttc ctagtacttt ttcagctgcg ttacggataa taccttctgt cagattcatt
      661 acatcattga aatcagtata tgctgtgtat gcttctaaca tcgtaaattc tggattatgt
      721 gtagtatcaa ttccttcatt acggaaaacg cggccgattt cataaacttt ttccattccg
      781 ccaacaatta gtcgttttaa atgaagttct agcgcaatac gcaaatataa atcaatgtcc
      841 agtgcattat gatgcgtgat aaatgggcgt gcggcagctc cacctgcctc attgtgcaat
      901 actggtgttt ctacttcaat atagccattg ccatctaaat agcgacggat ttcgctgata
      961 atttggcttc gtttcataaa tcggtcaaag ctttcgcgat tactgattaa atccaagtag
     1021 cgttgtctgt agcgttgttc aatattcgtt aagccatggt atttatctgg cagtggacga
     1081 agtgcttttg acaaaatcgt gatttctgaa gctttgatag aaacttcgcc tgtgtctgtt
     1141 ttcatgattt gtccagttac accaaagaaa tctccaaggt ctgcatgttt gaatacttca
     1201 taggcctcat cacctacttg gtcttttctt acataaattt gaatttggcc ttcacgatct
     1261 tgtagatgcg caaatccagc tttccctttt cctcggcgag tcatcatacg accagctaca
     1321 ctagcggtca atcccatttc tgctagttct tcttttgttc ttggatcaaa tagttcatgc
     1381 aattcttctg agttgtgcgt gcgttcaaat cgttttccaa atggatcgat tccatcttca
     1441 cgcaattgtt ccattttttg acgacgtaca agcatttgat catttaaatc ttctacttga
     1501 tgttgttgtt cctgtgtcac aaaagttcct ccattctcat gttaatctct ttcctataat
     1561 gccaatgaaa cacaaaaaaa gcaagccgaa cttggaattt cggcttgaaa attcacgaaa
     1621 aacttagaaa tcacaacgtt tgtttcaata gtactttttc cgctttttct acaaattgat
     1681 ccagcaggtc attgatttct tgctgttttt ctgtctgatt gattgctact ttcactttcg
     1741 ctgctcgagg aatccctttt aaataataag ccgcatgtgt tctgaattct ctacaagcta
     1801 ctttttctcc tttgagatct gctaagcgtt gtaaatgaag tttagctgta gcaatttttt
     1861 cggctggtgt tggttcagga atcagttccc ctgtttcgag ataatgctgt gtgcggtgaa
     1921 tcatccatgg attgcccagc gctgcacgac caatcatcac accgtctgca ccgacatagt
     1981 caagcatcca ttttgcatct tctggcgttt tgacatcccc gttccccata aatggaatcg
     2041 tcaaatgttt tttcacttct ttcaatactt cccagtccgc ttttccttca tacatctgaa
     2101 cccgtgtacg tccatgcata gcgatggcac ttgctccagc tgattgtgct gctaatgcat
     2161 tttctacagc aaagacgtgc tcttcatccc aaccaatacg catcttgatt gttactggga
     2221 tatttactgc tgaagaaaca gcttggacca tttcgtatac tttctcagga tctaaaagcc
     2281 attttgctcc tgcttctgct ttgattactt tatttactgg acagcccata ttgatatcta
     2341 ttatatcggc agctgtgttt tcttcgacaa attgagcagc ttcaactaga ctatctttat
     2401 ttccgccaaa tatctgtaaa cttaatggat gttctgtttc ttcaatgtgg agcatctcta
     2461 aagttttttt gtttctgaaa tgaatacctt ggtcactgat catttcacat acgactaagc
     2521 ccgcaccaaa ttctttgaca gtgactcgaa atgctgaatt tgttattcca gccatcggtg
     2581 caacaacgac acgattaggg atttccacat tgccaatttt ccatgtgtgt tccacttaaa
     2641 tccctcctaa ggcttctttc ttcaatccat ctaattcttc ttcgctatac ttgtatttgt
     2701 tattacagaa agaacaaacc gcttctgcac cgtgatcttc gtctatcatt gcttggattt
     2761 cttctgcacc taacgcgata attgcttctg caaatttttc ttttgaacag tcacatttga
     2821 attgaacagg cattttttcc aaaatgttca attcttctgt accaagcaat cctttcaata
     2881 tttcttctgg tgtctgtcct tcatctaaga gggtagagat tcttggtgtc gtttttaatt
     2941 gttcttcgat cttgctgatt gtttcttcat cggcacctgg catgatttgg atcatgaatc
     3001 ctcccgccgt cttgatgctg tcgtcagtat tgaccaatac actcagtcca acagctgaag
     3061 ggatttgttc tgagatagca agatagtaag taaaatcttc agcgatttct ccagaaacaa
     3121 tcggcgtttg cccagaaaaa ggttctttta atcctaagtc ttttgtgaca gtaaacattc
     3181 cttgtgttcc aactgctccc cgcacatcga ttttaccttc actatttaga ggaagactga
     3241 gatgcggatt tttgatgtaa cctttcacat ctccctttcc atttgcatct actacaattc
     3301 ctgttgctgg accatcgcct tggattcgaa cagttagttt gtcttctcct ttgagcgtcg
     3361 caccaagtag cagactaccg accaatgtcc gtcccaaagc agctgaggag gtgtgccaag
     3421 tatcatgacg tctttgtgcc tccgctacgg tatttgttgc ttgaacggcg tatgctcgga
     3481 cgaatccgtc gtgagcaagt gccttaacca aataatcttt catttgttat gtactccttt
     3541 ttccgttttt aaactcatag tgaatcatac tagcaactac tgcttttttc aactttggaa
     3601 tgcttctttt aaaaataatt cagaatcatc tagaaaacag gacatcaccc tatttacaac
     3661 ttaaataaag aaatctcccg aaaaccggtt tttgttccgg ttttcgggag tcatatcaga
     3721 tcaattgacc tatatttttt tatttgtatt gatcgtctga atgattatct tctgattgtt
     3781 gagaatctga atcatgttct gctttatttt cctcattcag ttcatgtttt gcttcttcaa
     3841 aatcacgttt ttcttccgct tgtttttcag cgtctttttc ttccaaagca cgttttgctt
     3901 cttcaaaagt tttcgcttct ttttcgcttg gataatcatt tgactcagta ccttcaggca
     3961 tcacaccgtg ttcaaacaat gacttgattg ctttggcatc caatgtttcg aattccaaaa
     4021 gtttttcagc aatcagttta tgctgtgcac gatgagcttc gatgatttct cgagctttat
     4081 catgagcttc catcaagatt tttcgtactt cttgatcaat ctcgaaagcg acttgttccg
     4141 agtaagcttt tgtttgacca tagtcgcggc caacaaacac ttgatggttt ccttcatatt
     4201 gaacaggacc taaacgatca ctcattccat attctgttac catgcttcgt gctagagctg
     4261 tcgcttgctc aaagtcattg gaagcaccag ttgattggac attgaagatg atttcttcag
     4321 ctgtacgtcc accaagtaag cctacgattt gttcaaacat atcttctttc gtcatcaaga
     4381 actgatcttc ttttggtaaa gcgatcatat atccgccggc gcgtccgcga gggatgatcg
     4441 ttactttgtg gacgacccga gcgcgactca atactaatcc gacaatcgta tgaccagctt
     4501 cgtgataagc aaccatttcg cgttcttttt tgctgattac gcgatctttt ttagctggac
     4561 ctgcaatcac gcgatcttcc gcttcatcga tatcagaagc atcgattttc tttttatttc
     4621 ttctagcagc tactaacgct gcttcattca agacattttc taaatctgct ccggcaaaac
     4681 ctggtgtctg ttgagccaca actttcaagt caacgtcatc tgccatcggt ttattccgtg
     4741 catggactcg caagattgct tcacgacctt ttacatctgg acgtccaact aaaatctggc
     4801 ggtcaaaacg gcctggacgt agtaacgctg ggtctagtac atcagaacgg ttggttgcag
     4861 caatgacgat tactccttca tttccgtcga agccatccat ttctacaagc aattggttca
     4921 atgtttgttc gcgttcatca tgtccgccgc ccataccggc accacgttga cgacctaccg
     4981 catcaatttc atcaatgaaa atgatagctg gtgcgttttt cttcgctgtt tcaaacaaat
     5041 cacgaacacg acttgctcca acaccgacaa acatttctac gaaatcagaa cccgagatcg
     5101 agtaaaacgg tactccagct tctccggcaa cagcttttgc taataaggtt ttacctgttc
     5161 ctggaggtcc ttctaaaagt acacctgccg ggatacgggc acctaattca acaaatcggc
     5221 gaggatcttt cagaaattca acaacttcaa ctagttcttg tttttcttct tccgcacccg
     5281 ctacatcaga aaaacgtacg cgattagctt ttttgtctgc ttctttggct tttgatttac
     5341 caaagttcat gacacggccg ccaccgccac cgccgccgcc ttgttgtccc atcatcatgt
     5401 aaaagaaaaa gatgatgatt acgattggca agaagctaag caatagggaa acccatatac
     5461 cgctgcttga ttcttctttt actgttgtag caactttgtt ttcttttgcc agttctgtta
     5521 cttggctcaa tgttgtatca tttggcaaaa tgattgttgt gaaatgggta gtagtcgtat
     5581 ctgttgaacc taagatagct aacccaccgc tgttagcgac ggtctgctgt tctttgtatt
     5641 caccagtgat cttatataca ccatttgcag gctgcacttc aaattctttg atcttgcctg
     5701 cttgtagttg ttctgtgaat tttgagtact cgatatctga cgatcgctgg ccgttattac
     5761 caaaaatgaa ataaacgacc attaccatcg ctaagattac gaggacataa tacaaggcat
     5821 ttttcatcat gccgttgttc tttttgttca tagttgccct ccctaagcgt caatttaatt
     5881 taacagtttt ttatcaatcc tgaccattct attgtaccat aatttaattg agatacagca
     5941 ttaatttgat tgataaacac taggtttcaa tacaccgatg tacggaaggt tacgatatgc
     6001 ttctgcataa tccaagccat aaccgaccac aaattcattt ggtacgttga agccaacata
     6061 atctgcttcg atatttacta ctcttccttc aggtttgtca agtagtgtaa caattttgac
     6121 tgattttgct ttgcggtatt tgaaaagatc cactaaataa gcaagtgttc ttccgctgtc
     6181 aatgatatct tcaacgatca acagatcgcg accttctaca ttcgtatcta agtctttgac
     6241 gatttttact tcccctgacg agactgttgc attcccgtag cttgaaacat ccatgaaatc
     6301 caattccaaa tacgtatcga tagaacgaac gatatctgcc atgaatggta ccgctccttt
     6361 taagacacct actactaggg gattggtgtt ttggtaaatt tctgttaact ctttgcctag
     6421 ttctttgcaa cgaacttgta tctcttcttg tgagatcaaa attctctcaa tatccttttc
     6481 caacatcagg ttctccttcc aattgcttct ttttgatatt tgtaaagaag tatgtagtgt
     6541 attttatcag tttcttcacg aatactcaaa tatgaaaagg caaaaggtat caagctatat
     6601 atatttcttt tggcatctgt aatgatccaa gcatgctgcc tttgtgaatt aggtactttc
     6661 tgatcgataa aatatctaga tacttttttt gtgagattct ctgttaattt aatgcggtct
     6721 cctgcttttc ttttttcgac atacagttgc acatcagcag gaatccaaat gtcatgagaa
     6781 aatagagacc atgaatctgt tgctttgatg tcccctgcat tttcaggttt gaccagacca
     6841 atccattctg tttcattcaa atatattcct tgttctggaa tcagcaacaa gcgctggtct
     6901 tctgtctggc tagttgcttg tttttctttt ttagagagta caacaaaatg atactctctt
     6961 ttcagtatcc aattattgcc aatactgagt tgccattggc tttttttctg ttgccactgg
     7021 tctaaaatcg actccatttg ttgttctttc aaaataattc ctgtttttga gaatgctttg
     7081 tcgaaaaagg agtaaaaaaa atagtatcgt tcagcatctg tcatttcttc aatcatttct
     7141 gcagaaaatc gaaattgttc ctcccactgt tcgacttcct tttcgatcaa ctgtcccata
     7201 tatttttgaa tgacttggtc tgcccattgg atctgttgcg aaaattgctg gaaatgtctc
     7261 aacgcctgtg tattttcttg tttcaattga ggaactacca aatgacgaag ccgatttctc
     7321 tggatatcta acaattggtt tgtctgatcc tcaaagtaaa caagctgcga ttccgctgca
     7381 taagtatata ggtcttcttt gctaaaactc agcaacggac gaatcagtct gcccgtagca
     7441 aatggttgta cttctttgat tccagaaaaa gtatttaact gtcccccacg aacgattttc
     7501 attaacaccg tctcgatttg atcatctccg tgatgagcag tcatcaacgt gtcatattgt
     7561 ccttcttcca tcacgcgagt gaattcttga taacgaaagt tacgagcttc tgtttctatg
     7621 gcggatttgg ctggatcttc ccaaatactt acatataaag ggagattctt ctcttcacaa
     7681 tatgagcgaa gataggcagc ttcttctgct gattcttctc ttaattggtg attgatgtgg
     7741 acgataccta aagaaaaacc gatttggcgt tgcacttgta aaagtaaatg gagcaaaacc
     7801 atcgaatcaa caccacctga taccgctgct aaaattctcg atccttgttg ccagaatcct
     7861 tgttcattcc cgtgccgaat aaatgactgc tgtaatagcg gtgctttttt cccgcctttt
     7921 tcaacgttca tcctttccac accctttctt cctaaaaaaa agagagcggg aaaacgtcta
     7981 aaacgacaat taacctgccc tctgttgata ctatgaccca aatagtcgca ctatcattat
     8041 ttgcggcttt ttagctgcga cgtccgccac ggccaccgcg ctttccttct gtgtttcgct
     8101 tcaatgaaga taagcggtca tcgctatctt tcaaaaatga actcatcaat gaatcgaagt
     8161 cttctttttg agctgaaggt tgactgcgag aaaaagattt tttctgtgct ggacgatttc
     8221 ggttgtcacg gggatctttt tgttgatatt ttttaggacg gctttcttct ccagattcag
     8281 caggttgttc ctgcgctttc cggatagata gtccgatttt tccatcatca tttactgaaa
     8341 taactttaac tgttacttca tctcctacac ttaaaacatc atggatgtct tttacatagc
     8401 catttgacac ttcgctaata tgaactagac ccgtttttcc agcacctaga tcaataaacg
     8461 caccaaaatt tgtgattcct gatacttttc cttgcagttt tgctcctacc tcgattgaca
     8521 taaaaaaaat gttcctccta attatttccc ttttttatat tcctgcttat tttgcagttg
     8581 tagaactagt tgattgatct gtttcatttg tcgagctgtc tgtatttgat tctaatatag
     8641 gataaacttt ttcaccgtct tttgagtaaa agaatttgct tctggcaagt ttagctacat
     8701 actcatcatc tttcagcaat gaaacatctt ggtgcagctg atcaacgtct gcgttgactt
     8761 ctttcatttc agtatttgct tcgactctca attcgttcaa ttgatgcatc ctttgcatgt
     8821 catggaaaat ctgcacacct attatcgcga aaatgaccaa agcaccaaca aaaattgcag
     8881 ccagtctgcg tcttcgaaaa atcagttgac gttgttgttg ctgaaattca gcatactttt
     8941 tctttgcata ttccgtatct agcgcagcga ttttattgct ttttttcgtc acttggattc
     9001 gctccaatct ttttgattgt ctttttcatt ataccaatat cgtgaaagct tgtctaatct
     9061 atttctctag tgtttctgtg cgattttcag aaataatttc gtacattttt tgtgcatctt
     9121 cttttttggt tgattcatgt aattccgtaa ttttcacttc caacgttttg ttgccaaact
     9181 ggactttcaa aatatcgcct actttgacat cactggaaga tttcgccaat ttaccgttga
     9241 tttgaattct tcctttatca gctacttctt ttgctactga tcgtcttttg atgattcggg
     9301 aaatttttaa aaatttatct aatcgcatat cttattcctc actttttaat ttttttattt
     9361 aatcgcagga ttttcttacc aaaaggcaac attagccatt ctcgtactgt aaacagacga
     9421 agacgaatca ctgcataaat gaacacagaa gccccgatcc caactcctat cacgctgaca
     9481 aaaaaagcag tggaacgatg agttacagga ccaaatacta tattcaatac accataatac
     9541 agcagcagta ctactgtcat acaaagaagg ctgaacatca acttccgtcc aaaatgccgt
     9601 tctttccaaa aagcatttag ctcttttgtt tcaattcgaa caaaatacca aagcgtcaca
     9661 cctaatccta aaagggtaga caggcttgca cctgctgttc ctaataaacc ggtcagaaaa
     9721 gaagtagtca atccttttac caatagtccc catcctgcgc cttttaaaga agggcgaaac
     9781 gagttcttgc tttgagcaat actttgataa gcttggatga ctgcagtgaa agcaatggaa
     9841 aaaacaaata atacaagcgc tgcatttccc gcataatctt taaacaacgc ataattgata
     9901 taagggagca gcaaggctaa tcccaaagac gcagctaatg ctaaagcggt cgtcaatcta
     9961 agatagattt tggctgtctg taaaaactga cgatagatcc ggttggtcaa atgacgagtc
    10021 aacgcaggca ggaatgtcgc acttaatgca gtggcaatca ctaaacctaa ttgtactaaa
    10081 ggctgacctc gatcatagac cccttttgct atcttcgcac cgtattctga cagtccgtaa
    10141 acttccaaag cattttttac aaagaaagag tcgatcagct ggaaaaagat aagcaatcca
    10201 ctataaatcg aaaccagtcc gccttctacc agaaaacgcc ggatcaaggg ctttgacggc
    10261 tgtttgaaca atggaaaccg tcggaagctt aacgctcctc catgaatctt ttgttcatag
    10321 tagtgaagga tcccatatgc gcataaaccg ccaaaaacag ctccactcat tgctgccgtc
    10381 cctgtttggt acaccgtcca tccaagcttt ctaaaagcaa acgcactaca gacaatcaca
    10441 aaaacacgaa cgaactgctc aactacttga gaaacagcag ttggttccat caagaatctt
    10501 ccttggaaat tccctcgata aaaagataga ccaggcatca gcaaaaaggt aaaggaaact
    10561 acttggatca gcggtttcaa ttgtatgtct cccatcatcc aagcaatcca gctgctaaat
    10621 gcaaagacaa acaaccacaa aaagacacct gtccaaaata ctaagggata aagattttgc
    10681 aaagcttgct ttcgctcgaa aggattcttt ctttctgcaa cgtactttga tatgaactgc
    10741 ggaagaccgg ataaagctaa agtcattgct atcccataaa ttggataaac ttgctgataa
    10801 acataaaaac cttcgtcgcc gactaagttt tggaggggaa ttcggtaaag ggcacttaat
    10861 acttttgcta tgaaagaagc aatcgtcaat acaaatgctc cttgcatgac gcgccgcatt
    10921 tctttatgat ccaaatcatt gctccttcct acgctgacag atatttttgc tcacgcaacg
    10981 ctttgacaaa cttttggatt tcctgaagcc atactgcttc ttccatttgg ttggggatcg
    11041 tcaagcgtat caccatctgt tctttttcaa cgcctagact ggcttttagt tttgtcgctg
    11101 tcagtgcttc gaataactgt tccacactat agcgttttgt tccaacttta cttagagtaa
    11161 agactatatg cgcctcctgt ttccttatcg tttctaggag cgctcgatcg ccatccattt
    11221 tgatctgccc aattgtcaag agatgtgcta cttcttctgg atattctcca aaacggtcga
    11281 gcagatcatc ttctagttca tctagcattt cttgcgaatc aagttcacga attcgtttat
    11341 agatctcgat tttctgccgt tgatctgcca cgtatgtttc aggtagatac gcatcgacac
    11401 cgaggtcgat ctcaacagtg gtcttctcca cttgactatt ctttccttgt ttacgagaaa
    11461 cagcttcgct tagcatttga gaatacatat cgaaaccgac tgcatcaata aatccatgct
    11521 gctgagcacc taagagatta cctgcaccgc gaatggaaag atcccgcatc gcaatcttga
    11581 atccagatcc cagttctgta aaatctttga ttgcctgaag acgtttttca ctgacttcgt
    11641 taaggatctt ctgctgctca tacataaagt aagcatatgc gacacggctg cttcttccta
    11701 cccgccctcg caattggtat aacgtggata atcccatata atcagcgttc tcaacgaaca
    11761 acgtatttgc gttcgggata tctactcctg tttcaatgat ggttgtagtg acaagaacat
    11821 catattgacc ttcaataaat tcaaaaagcg tattttctaa ttgcgcctct gtcatttgcc
    11881 catgagcata accgatccgt gcttccggaa cgagttcttg gatttcttct actttttgtt
    11941 cgatcgtttc tacccgatta tataaataga atacttgtcc acctcgtccc atttctcgat
    12001 ggattgcttc gcgaatagcc ccaggatttt tttccataac atacgtttgg atcggataac
    12061 gattcgcagg cggtgtttcg attactgaaa gatcccgcac gcctaacatc gacatatgca
    12121 aagttctcgg aatcggtgtt gcagtcagag tcaaaacatc cacttgtgca cgtaactgtt
    12181 tcaatcgttc cttatgtttt acaccaaaac gttgttcttc gtcaatgatc agtagaccca
    12241 aatcgctaaa ttcaatatct tttgacaaaa ttcggtgggt tcctacaaca atatcaactt
    12301 gacctgtacg cagttgttcg atggtttctt tttgttgctt tcttgttctg aaacgactta
    12361 atagcccgat atttacgggg aaaccttcaa atctttccag catcgtttca tagtgctgct
    12421 gtgccaagat cgttgttgga actaaaaagg ctacttgttt gctttccttt atcgctttaa
    12481 aggccgctcg aagcgctact tctgttttcc cataaccaac atcacctacg agtagtcgat
    12541 ccattggttt ttctttttcc atatcccgtt tgatctccgc tgcacttctc aactggtcat
    12601 cagtttcaga gtaggggaag gcattttcga attctttttg gtaggcgtca tcaggtccaa
    12661 aagcatatcc tttttctgac tctcttgcgg catataattt gattagatcg tcagcgatat
    12721 cctcgatttt tgaagagact tttcgcttgg ttttcgtcca ttcacttccg cctagcttat
    12781 tgatgcgagg cgctttggct tcagaggcga catatttttg gatcagattc agttgagtaa
    12841 caggaataaa cagtttgtcg tcgttttgat acaaaatagt catatagtct tggtgaacgc
    12901 catctacttc tagcgtttcc atcccaatgt atttcccgat accatgattg gcatggacaa
    12961 cgtaatctcc tgcttttaac tcattatagc ttttcaatcg ctctgcgttt gttactgttt
    13021 gacgtctcgt ttgttttttc gtcgtttttt ggaaaatttc tttttctgtg atagctacta
    13081 ttttttcttg aggaagttca aaaccagcct gcaaagctcc ttcaactaat tgtacctgtc
    13141 ctctgatcaa tgcatttttt tctgtttcta ctactaatat gtcttcatct cgaagcattt
    13201 gttctgcttt gcgtattctg tcctttgtcg gaataaagat cacaacagtc tgtttttgct
    13261 tgcgccaacg gtccatttct gttttcagca atggcatttg tccgaagaac tgttgcatcg
    13321 tccgatattg aaaattatgg attgcttgga aacgaagatt tcccatccct ttttggaaga
    13381 gtgagaaaaa ggttgtggtg aacttttcct tctgcacgat tttttgtata tctgctgaaa
    13441 atgtctgctc agaaaacacc cgcaattcgc tgattttttg agtctgccat tctgccgctt
    13501 ccctttcgat ttcccgattt gtttccatga ttcgctgata atcatcaacg actagtaaac
    13561 tatttgaagg gaaataatcc aagatcgtca cagattcttg gtaaagaaga tctgagtaga
    13621 attttgcttc ttctgtcggg acacctgctt gccagcttga agtcagctga ccgaagtaat
    13681 cttgcaaaaa ctcgcggtct gcttcttctg tggtcgcagc aagccgtttt tctagcattt
    13741 tttgcatttg ctctattcca tgttctagat cctctggtcc gtagacttgt tcactcgttg
    13801 gggaaaccca gatttcttcc gttttttcga ttgagcgttg tgtttctgct tcaaaatacc
    13861 gcatagaatc tatctctaca tcaaatagtt ctacacgaac aggataggtt gtcgttaacg
    13921 ggtaaatatc gataatgctt cctcgaatac tgaattctcc cggttttgcg accatctctt
    13981 ctcgtacata gcccatcaaa gtcaattggc gaggaagatt ttccacgtct atctcatcac
    14041 caatatgcca attcaattgc gcctgtagcc aagttttctt attcggcagt cgtttgtgca
    14101 aagatgcgac tggcaacaaa tagatacctg cttttttttc ttgaagtgcg ttaagcgttg
    14161 caactctctc gcctcgcgct tctggagaag aaaaggccat ttcagcagaa agcacttcat
    14221 ccactggaaa taaatggatc tgatcttgcg gaatcacatg ttgcagatct tctgctaact
    14281 gattcgcata atacaaattt ggcatcagaa taatcatgtt tttatttgtt ttcttaaacg
    14341 ctcgagcaaa tagaagtgtt ttcgctgagc ccgctaatcc tgtgattagt tgtctaggca
    14401 ttttttcttc taaattgctg acccattctt ttacttgcgg atcttttccg actaattgaa
    14461 taatatccat tccttttcct ccttcctcaa ttgaatcgat tcatcgcatc cacgaacgaa
    14521 tgcccttcta tgagatattc gactgcttta acagattgac acatgctttc ttctatcaaa
    14581 ggctgatttt ctttgctgaa aggactaagc acatgctgga ctactgtttt tttcccttct
    14641 ggcctgccga ttcccacctt gattcgatca aagacattcg tattcaaatg ggaaataata
    14701 cttttgatac cgttatgccc gccggcactt cccttttgac ggagccggat ttttcccact
    14761 gccagatcca aatcatcgta gattacgact aattcctctg gataaatccc aaaataagtc
    14821 attagtgggc cgactgcacg accagattca ttcatgaatg tttgtggttt gactaaaagg
    14881 atcttttctc cattatgaaa aaattcggca acttctgctt cgaacggatt ttttttgaaa
    14941 gtagcttgat gctcgcgtgc aattttatcc acgaccataa agccgatatt gtgttttgta
    15001 tattggtatt tggtacctgg gtttcctaac ccgacgatca ttttcatttt tgttttccac
    15061 ctaattctaa aaagcagcac aaaaggctgg actgctaatt agcggtccag tccatcgagc
    15121 ttttttcttt tttacacttg tcaatgcata gtataacaca aaacaaggcg tttcggctaa
    15181 aagagaatcg ttaataaatg ataaagaaat taaaaatttc ttcaaagttt aatgaaataa
    15241 ttgatatata aaaatagtga aataacgcac atgtaagctt ttacatataa tacaaccttg
    15301 ttatctgtta tattttatag ccaaatagcg tgacatgggg cttgagaaat gttagcataa
    15361 gcatgggaaa aaacaaatca atggaaggat tgatactaaa tgactgcagc tgcagaaaaa
    15421 aaagatcatc aaaaagttat tcttgttgga gacggcgccg taggttctag ctatgccttt
    15481 gctctagtta ctcaaaatat cgctcaagaa gtaggtattg tggatatcaa tactgctaaa
    15541 actgaaggag acgcaattga cttgtctcac gctttggcat ttacttcacc taaaaaaatc
    15601 tattctgcta cttacgcaga cgcacatgat gctgacttag ttgttattac agctggcgca
    15661 ccacaaaaac caggtgaaac tcgtttagac ttagtaaaca aaaacctaaa aatcaaccgc
    15721 gatgttgtca cacaaatcgt tgaatcagga tttaacggta tctttttagt tgccgctaac
    15781 ccagtagata ttttgactta ctcaacttgg aaattctcag gtttccctaa agaacgcgta
    15841 atcggttcag gtacctctct tgactcagct cgtttccgtc aagcacttgc ggaattagtt
    15901 gacgttgatg cacgtaacgt ccatgcttac atcttaggtg aacacggaga ttcagaattc
    15961 ccagtttggt cacatgcaaa tgttgccggc ttgcaaatct atgaatgggt aaaaaacaac
    16021 ccagaaatcg atgaagaagc tatggttaac ctattctttg gcgtacgtga cgctgcttac
    16081 acaattatcg agaaaaaagg cgctactttc tatggtatcg cagtagcatt agcacgtatc
    16141 actcgtgcca tcttagatga tgaaaatgct gttcttcctt tatcagtatt catgaatggc
    16201 gaatatggat tgaacgacat ctacattggt gcacctgctg ttatcaaccg tcaaggtatc
    16261 caaaaagtaa tcgaaattcc tttaagtgac agcgagcaag accgtatggc tgcttctgct
    16321 aagcaattaa aagaaattct agatgaagct tttgctaaac tagacgctga ataatctttg
    16381 aacatgacgg aaaacatcta ttcggtgttt tccgtttttt tattttatca cccttatggt
    16441 ttctaaattt tttcataaag tagagataac cttcgtcttt tcctctaaat tatgctatca
    16501 tgagaccgtt ccaccctaaa cttttactta aggagttgtc gatatgacaa gatcttcgca
    16561 tcgaaaaaaa tcgaaacatg ttgctttgct ttcagttctt ggtgttctct tagtgctgat
    16621 cagcttttat acctatcgca gtacatacta cacaaagcat tttttgccga atacagaaat
    16681 aaatggaata aatgtcagca atctaacagt cgaaaaagca aatgaaaaat taaaagaagc
    16741 ttattctgat aaaaaactgg ctattaaaga agatggaaaa gtctggcagg aagtaccaaa
    16801 atccgagctc ggctacaaag atgatttcac ttcggagctt tctccgatcc taaatgaaca
    16861 aaacggatgg acttggggaa tgacttatgt ctcagcggca gaaaaacaag aaatagatcc
    16921 tgtcagtcaa aaccaccaaa aactagacac taccgttcag acattgacaa ctaagctgac
    16981 tgatttgaac aaagaccgga cacctactac tgatgcaacg atcgaaaaag caggtgactc
    17041 tttcgttatc aagcctgaag tcaatggaaa tacgatcgac gtcgatgctg cggtcaaaca
    17101 attaaaaagt gcggtaaact ctggtaaaga tacaattgaa ttgactgaat tcaaagaaaa
    17161 accaaaagta acatctgaag acagctcact gaaagaacaa ctcgcatcca tgaatgctat
    17221 cgcaaatgta aaagctactt acagtataaa cggtgagact ttccagatcc catcaagtga
    17281 tattatgagt tggctgacct acaatgatgg aaaagtcgat ttagatacag aacaagtacg
    17341 tcaatatgta acagatttag gcacaaagta taacacaagt acgaatgaca caaaatttaa
    17401 aagtacaaaa agaggagaag ttacggtccc agttggcact tacagttgga cgatccaaac
    17461 agacagtgag acagaagcat tgaaaaaagc gattctggca ggccaagatt ttactcgttc
    17521 acccattgtg caaggtggca caaccgctga tcatccattg atcgaagata cgtatatcga
    17581 agttgatctg gagaaccagc atatgtggta ttacaaagac ggaaaagtgg cccttgaaac
    17641 agatatcgtt tccggaaagc caactacacc tacacctgct ggagtcttct atgtttggaa
    17701 taaagaagaa gatgcaactt taaaaggaac aaatgacgat ggaacacctt acgagagtcc
    17761 ggtaaactac tggatgccga ttgactggac aggtgttggt atccacgatt cagactggca
    17821 acctgaatac ggtggagact tatggaaaac ccgcggttca cacggctgca tcaacacccc
    17881 accaagtgta atgaaggaat tattcgggat ggtcgaaaaa ggaacgcctg tattggtctt
    17941 ctaacaaaaa taatatataa aaagaaagca cccgtacgat tggtacaggt gctttctttt
    18001 tattatctaa caatgtgcta cttacatttc agcagcagta aagacttctg aaacatcatc
    18061 atcgtcttct agcttatcta ctagacgttc caattgctct ttttgttcct catttaaatc
    18121 aatcgtcgtt tgtggaatca tcgtcaattc tgcttgcgcc aaagtgaact ctttttccaa
    18181 ctcatctcgt acagcagcaa aatcttctgg tgcagtataa atctcgaata cttcaggaga
    18241 agtttgcaga tcttctgccc ccgcctctaa tacatcctca aacatcgtct cttcatcaac
    18301 agtcaaccca tcgcgttcaa tagcgatata tcctttgcgg tcaaacaagt aactgactga
    18361 acccgtttct cccagtgatc caccgtttcg agtaaaagct actcggacat ttgtcgctgt
    18421 ccgattacgg ttatctgtca atgcatggac taagattcct actccacccg gaccatatcc
    18481 ttcatacgtg atttcatcgt aattcgtttc atctacggca ctcgtagcct ttttaatcgc
    18541 ccgttccaca ttgtcgttag gcatatttgc agcttttgct ttgtccacaa caagccgcaa
    18601 agctggattc atagatggat caggaccgcc tgctttagct gccatataaa tttcacgaga
    18661 aagtttctga aagactttcc ctcgttttgc atcttgggca ttttttcttc cttggatatt
    18721 atgccattta ctatgtcctg acatgatttt tcctcccttg ttcttttgag aatacacttc
    18781 tattctagta ctatttcaca aaaaaacaaa gccacagcca atctataaac gcttcttgaa
    18841 tgccgcaaaa agcacacata atatcacagc agtcagagca ccgatcgaat ccaacatgac
    18901 atcttggaac ataggtgttc gtccaccggt catcatctga tggaattcgt ccaaacctgc
    18961 gtaccctgtt gctgaaagcc aagcaaggat cgctgtcagc caccaaattt ttagcttggg
    19021 gaaaacacct aaaaacaagc tgcctcccaa aataaaatag gtaccgaaat gtgcgccctt
    19081 ccttaaaaag aactctaaaa atttggcgta gcccagatgg ttgatactca ccatacttcc
    19141 accataatta aaacgtatac ccgctaatgt gtctttaaat ggctgattag gcagccagct
    19201 ttctaatcgc gaaacttgtg attgctgtcc gtaagtttga gaagaactgt aaaataagat
    19261 tataacgact atcagtgcga ttactaaata aatatttccg tttttcattt gtttttttga
    19321 agaattcata agtcacctct gtattttatc ttagactttt tttgaagaaa caacaatcat
    19381 tttcatagag acttcttcca taaaaaagtg ctatacttaa ttttgtatta caatatgaag
    19441 ggagtttttt catgagttat tcattaaatt ggaatctaga ttctattttt tccggaggca
    19501 gtcattctga tgctttgaac caacggatga agcaattgga agaccaaatg aacgagtatt
    19561 atcaccgcgt aacaaaatgg tcacctagtt ctgacaatgc agagcagtta aacgctattc
    19621 ttcaattgca agaaacgatt acgaatggtt ttacccaatg cagcagctat attactgcat
    19681 tgctttctgc caatgtcaat gattcagatg caaaggtctt atcaggcaag ctttacgcaa
    19741 tgctgcctcg tctgcaatca gccgaaactg tattgtcaaa gaaatttgca gaaatatctg
    19801 acaatgattg gaatcagatg ctttctcaat cttcgtttga aacaattgct tttcgtttaa
    19861 acgagattcg tcgtgatggc tcacaattat tatcagaagc tgaagaaaac attataaata
    19921 cgctttcttt agatggtcta aatgcttgga gcagtcatta tgatacgatt gtagccagca
    19981 tttcgattcc cttcgaacaa gatggacaag tagtcgaatt atctgctgga caagccttca
    20041 ataagatgat gggcgatcca gatccaaaag tcagagaaac acttttcgca gcatgggaag
    20101 aagcctggaa agaaaaggca cccctcttca cggatacttt gaatcattta gatggtttta
    20161 gactttctga ctatgaactt catggtgtca cagattttct acaaaaacca ttagagtaca
    20221 atcggttgaa gaaagaaaca ttgtctgtca tgtgggatac aatccagaaa aacaaacaac
    20281 cccttgttaa ttacttgact agaaaagcta atcttttcgg taaagaaaaa atggaatggc
    20341 aagatcaaga tgcacctatt attttaggcg atttgaaaga aaaaaccttt agttttgacg
    20401 aagcagcagc atttattatc gaaaacttta acaaattcag tccaaaaatg gctaaatttg
    20461 cccaatctgc ttttgaaaag agctggatcg aagcagaaga tcgtcctggg aaacgtcctg
    20521 gtggttattg tactgagtta ccagaaacaa aagaatcaag gatctttatg acctacagta
    20581 attctgttaa tgaggttgcg acacttgctc atgaactagg acatgctttc catagcagca
    20641 cgatgtggga tttaccttct ttaaatcgcg aatatgccat gaatgtcgca gaaacagcaa
    20701 gtacattcgc agaactgatc gtagccgatg ctacattaaa agtcgcaaaa acaaaagaag
    20761 aaaaaatcaa tttgctagat acaaaactgc aaaatgcttt agctatgttc atgaatatcc
    20821 attcccgatt catttttgaa aatcgattct atgaagcacg gcaagaagga ttagtctcag
    20881 aagataagat cacagagatg atggttgagg cgcaaaaaga aggctatcaa ggagctttag
    20941 ctacttacca tccatatttc tgggctgcaa aattgcattt ctttattgat gacgtaccgt
    21001 tttataactt cccatacaca tttggctacc tctttagttt gggcatctat gcttacgcca
    21061 accaaaaggg agcaaatttt gaagaagaat atatccattt actacgcgat actgcctcaa
    21121 tgacgacgga agatcttgcg aagaaacatt tgaatgtcga tcttacccaa ccagattttt
    21181 ggcaagcagg tatcgacatg gtgactgaag atatccaaac gttcatggaa ttgacagaag
    21241 aatttatctg atttctattt tatcacaata aaaaaagagt tagtccagaa tgggctaact
    21301 ctttttgatt aatcattctt acatgctgac agcaaagtca ggggcaaacc attgaactga
    21361 accaactttt acgctttcgc ctggttgagg agcatggata tattgtcctc cgcctaaagc
    21421 aatcgctacg tggtaagttc cgccttgtga cccccagaat aacaagtctc cagcttttgc
    21481 ttgagaaact gaaatttttg ttccagctga ttcttgagga actgtccaac caccgatgtc
    21541 acgaccagtt acttgcatgt aaacatagcg tgtgaaccct gagcagtcaa agccacttgg
    21601 atctttaccg ccccaaacat atggagtacc aatatatttg taagcttctg ctacgattgc
    21661 tgcaccattc acacttccag aaggagctgg agcaggtgtt acaggttttg gttgttcagg
    21721 tgttggtgtt ggcgttggag ccggagtact acttcctgtg ccgtttcctg tatcaacact
    21781 ttgatctgtt gatggtgttg taggcgcagg tgttgttgat tcttctgttg ttgaagattc
    21841 aggcactgtt gttgattctt ctgttgctga agattcaggc actgttgttg attcttctgt
    21901 tgctgaagat tcaggcgctg ttgttgattc ttctgttgct gaagattcag gcgctgttga
    21961 ttcttctgtt gaagattcag gtgttgttga ttcttctgtt gctgaagatt gtgtagctga
    22021 tgatgattct tcagtcattg aagattgtgt agctgatgat tcttctgttg ctgagctttg
    22081 tgcagtagat gaagcttgag tagcttgtgc ttcagcctct gcttgttcgc gtgcttcttt
    22141 ttcagctttt tcttgtgcag cttgttgacg agcttgttct gctagacgtt gttgttcacg
    22201 aatacgagct tgctctgctt cagcttctgc tttttgacgg ttcaagtcag ctttcttgtc
    22261 ttcagcagtt gcttgttcag cagctaatga agttttcagt acgttcaaat cagcttgttt
    22321 agataaaaga tcgccttttt gagattccaa agcagcttgg ttttcagcta attcttttag
    22381 tttagcatcg ttttcagctt ttttgtcttc tacagctttt ttatcttgtt tttgttgttc
    22441 catcaagtcg ttgtttgctt ttaccatcgt tgtcattgct tgaacgcgtc caatagcatc
    22501 tgctaatgaa tcagcattca atacagcatc gatgtagttt gagcttgtgt tgcttacttg
    22561 tgcttcgcgt gcttgttttt ggattgtatc ttcacgtttt tcaatacgtt cttgtaaatc
    22621 tgcaatgtct tttactaatt gtgcagattc ttgacgcaat gtatcttgtt ttgctaatag
    22681 gtcttgtgct tgtgtgttga tttcagaaac ttggctttct aaggcatcga tttgtgattg
    22741 tgcatctgct tgttgatttt tcaagtctgc aatcttttga tcttgctgtt gtatctgaga
    22801 atcaaaatcg tccgccgcgg cagcgatcgg tgatgctacg gcagtcaagg tcattgaaca
    22861 taccatta
//
LOCUS       DAFTHM010000037        22632 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFTHM010000037 DAFTHM010000000
VERSION     DAFTHM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.037"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            131..3658
                     /locus_tag="L7C88_001410"
     CDS             131..3658
                     /locus_tag="L7C88_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBP9558247.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3655..7377
                     /gene="addA"
                     /locus_tag="L7C88_001411"
     CDS             3655..7377
                     /gene="addA"
                     /locus_tag="L7C88_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBP9558248.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7446..7787
                     /locus_tag="L7C88_001412"
     CDS             7446..7787
                     /locus_tag="L7C88_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9558249.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8096..9139
                     /gene="pheS"
                     /locus_tag="L7C88_001413"
     CDS             8096..9139
                     /gene="pheS"
                     /locus_tag="L7C88_001413"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBP9558250.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9144..11564
                     /locus_tag="L7C88_001414"
     CDS             9144..11564
                     /locus_tag="L7C88_001414"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBP9558251.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="L7C88_001415"
     CDS             complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="L7C88_001415"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBP9558252.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12998..13735
                     /locus_tag="L7C88_001416"
     CDS             12998..13735
                     /locus_tag="L7C88_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBP9558253.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13749..14564
                     /locus_tag="L7C88_001417"
     CDS             13749..14564
                     /locus_tag="L7C88_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBP9558254.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14577..15224
                     /locus_tag="L7C88_001418"
     CDS             14577..15224
                     /locus_tag="L7C88_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBP9558255.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15240..15896
                     /locus_tag="L7C88_001419"
     CDS             15240..15896
                     /locus_tag="L7C88_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBP9558256.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16058..16879
                     /gene="racE"
                     /locus_tag="L7C88_001420"
     CDS             16058..16879
                     /gene="racE"
                     /locus_tag="L7C88_001420"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBP9558257.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16882..18237
                     /gene="rph"
                     /locus_tag="L7C88_001421"
     CDS             16882..18237
                     /gene="rph"
                     /locus_tag="L7C88_001421"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBP9558258.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18238..18756
                     /locus_tag="L7C88_001422"
     CDS             18238..18756
                     /locus_tag="L7C88_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBP9558259.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18863..19363
                     /locus_tag="L7C88_001423"
     CDS             18863..19363
                     /locus_tag="L7C88_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBP9558260.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19643..20563)
                     /locus_tag="L7C88_001424"
     CDS             complement(19643..20563)
                     /locus_tag="L7C88_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBP9558261.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20728..21741
                     /locus_tag="L7C88_001425"
     CDS             20728..21741
                     /locus_tag="L7C88_001425"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBP9558262.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="L7C88_001426"
     CDS             complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="L7C88_001426"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBP9558263.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
BASE COUNT         7535 a         3949 c         4821 g         6327 t
ORIGIN      
        1 tttgcgtata cttaaaaaag tagaaatatc agaaccttaa aaggatataa tttgaagaat
       61 atagaacaaa tgttcagtat tttttgatat aataaaggag caccgtatca tgtgttgaag
      121 gaggaaaagc atgtctttac aatttattct tggaaacggg aaaaaagatc accgtcaagt
      181 cttgatcgac gaagcatccg cttggctcga ccaggatgca agtaaccaag tatttttcct
      241 tgttcccaac tacagcaaat tcgaacagga acaagaaatt ttagcggaga tgcgaagaag
      301 aagcggaaaa aaaactttca gcacaacaaa cgttcaagta tttagttttt atcgtctggc
      361 ttggtatttg ctgcaacaga caactcttct tacaggaaat gaattatcag aatcaggatc
      421 tgcaatgatc ttgcgacaga ttttagaaaa aaatgaggaa gaattaacaa tctttcgcgg
      481 agaaatcaat aaaagagggt ttattcgtca attacaagaa ctctacagtg aattgcgtac
      541 aggaaatatt caaccagaag acctgatgct tttatttggt gattcaccta atgcagaaga
      601 ccagcaactt aaaatgaaag acttgaagct gattttttca gcttatgaca gcgaattgac
      661 tcaacgtgca ctaacaaatg aagatgcact atctatacta gcaaattata tgcagacaca
      721 agatttcaac aacgtcaaat ttattgtcag tggtttttct cgaatcaatg gtcaagagta
      781 tcaattactg caggcaatga tggaaaaggg gcaattggtt gtcgatttat tgctggatcg
      841 tccttataca gcggatcttc cagaagtact tacgctcttt catgagactg gaaagcttta
      901 tttccgtctt tttcaaagtg caagagaacg gaaagtccct atattagtgg accgatttgc
      961 accagagcag actcgtccga cagagcttca actgctgcaa acaatgtggg aagagacatc
     1021 tagccaaaag aaagcggcag tacacaaaat agggggacaa gagcatctcc atttgtggga
     1081 agctgaaaat ccaactgaag aagtccgaca attagctgtt gaaatcagac gactagtcag
     1141 tgaagaaaac taccgttatc gtgatatcca agtgctgaca aaaaatatgt ctttatatgg
     1201 aaatatcctt cggccgatct ttcaagaaat ggcaattcct ttttatatcg atgaagaaca
     1261 aatgatggaa aatcatccgc tgatcgaatg gatcaacagt ctgttcgctc ttgaccgcta
     1321 ttcttatcgg ctaagtgata ttatgcgttt tttcaaaact gaattatttc tgtcgacgga
     1381 agcagaaacc gaacttgatg aatggaaaca agagcgagat gaattcagga aaaaactgga
     1441 catcactgaa aatgtagcac ttgcttacaa ttatcaagga acttattgga ctcgtgaaaa
     1501 agactggcag tttgtggcgt atgattttga agcagaacag attgaagacg tacagtattt
     1561 ggaagaacag tcaaatacga ttagacgatt atttcagaaa gctgtaccag tatttttgaa
     1621 aaaaataaag aaaagcaaaa caggacaaga ggccgcaaat gttttttatc aatttttgat
     1681 ccaaagtggc gtacagcaac aattattgtt ttggcgtaat caggaagtag acagaggaaa
     1741 cttagaagcg gcaagaaacc atgagcagac atggggagcg ctgattgatc tgttggatga
     1801 atatgtagta atttatggtg aatcggcttt tgactggtca ctgttccaag aaatcattac
     1861 aagtggtcta gaaaatctaa gttatggtaa aatccctacc gcaatcgacc aagtgcgaat
     1921 caatcgtttg gaattagttc gaccaaatca agctgccgtc acttttgcat tagggttgaa
     1981 tgatcaagtg tttccagacc gaaaagagac aaaaggattg ttgtccagtg aagaacgaga
     2041 agtattaaat caggccttgc cagatggaca gtttttattc gacccatcaa aggaaagtat
     2101 ctcttttgag cctttccaag cctatcttgt ttttctttcc ggaacagatc gattatatct
     2161 tagttatgca caaagctatg acacagatgg ttcgctgaag atgtctcctt atttgcgtag
     2221 aatcacagaa tatttatctg ttcccgtcga gagaaaagag catttgacga tcgaaagcga
     2281 ccctaattgt tatgtaggga cttacagaag cggaatcaat acagtcaata ggatttatcg
     2341 attagcttta gatgaaaaaa aacctgtacc aaagcactgg caaaagctca aagaattagt
     2401 actgaattcg tcatggcgaa attttgcttt acagattttt gaaagtcagg aacatttaaa
     2461 tgttcctgtt tcgatgccag aaaaaatggc ggaagagctt tatggaaaag agatttatac
     2521 ttcaatttca cgtatggaga atttttataa ttgtgaatac aaatacttca tgcaatttgg
     2581 tttgaaattg aaagaacgaa ctgtttatgg tctaactcca gcagcaactg gtgattttta
     2641 tcatgaatca ttggatcgtt tcttcaagct actgttttca aaccaattat ccttagtgaa
     2701 tatgtccgat gcgcagcgta gagactttac tgaaaaagtg ctgcaggaag tattcggaga
     2761 acttcggttt gagatattgg atagttctgc aagaatgaac tatatccgct accagttagg
     2821 acagacgatt caaaaagtga catgggcttt gcaaaaacag agcaaaaata caggcatgca
     2881 tcctcttcag acagagattc tatttggtca gattgctgga gcaaaaggta tcacaggtct
     2941 ggaattaccg ttgagtaatg gtggaaaact ccatgttcga gggaaaatcg atcgaatcga
     3001 tgtagcttct gaacaagaag atacttggct aagcgtcgtt gattacaaat ctagcggacg
     3061 ttcattcgat gtcacagaag cttattatgg catggctatg caattattga cgtatctgga
     3121 cgtagcattg atggatgcgg tacgtttgac tggaaaggcg gctgttaaac cagcaggatc
     3181 atattattta catgttcata atcctgtatt gacggagaca gatgatgtag agaagaatac
     3241 attgaaaaaa tttagttatg atggcgtttt tgtcgatgat cccgctcttt tagaagtact
     3301 agatcattca ctggaagcaa aagaacaatc actgatctat ccagtgaaaa aaaatgcgaa
     3361 agatgaatac caaaaaggta gtttcagtaa agacaaattt ttcacggaag aagaactgca
     3421 actattcatg gcgcataatc gggaaaatat gcggttagct ggagatgcga ttacttccgg
     3481 agaaatcaaa ctaaatccag cttataaaga taaacagcgg attgcctgcg aattttgtcc
     3541 attcagaagc atctgtacgt ttgatgtgat gctgaaagaa aataattacc accgtctgga
     3601 gaaaatagat aaggaagaag cactgcgtag aatattgaaa aggagtgaag aagagtgaat
     3661 caaattcctt taaaaccgca aaatgaacga ttcacagatg atcagtggca agcgattttt
     3721 gatcaaggag ataatctatt agtctctgcg tctgccggat caggtaaaac tacagtgctt
     3781 gttcgaagag tgattgaaaa actaaaaatg ggttttgata tcgatgaatt attgattgtg
     3841 acatttactg aagctgccgc aagagaaatg aaagaaagaa ttcaagaggc attacaagaa
     3901 tccgtcaata gcgaaagtga ccctgtacgt agacagcatt ttactaagca gttagtttta
     3961 ttgcccacag cgaatatctc aaccttacat gctttttgcc tgacagttat tcgacgttat
     4021 tattacttaa ttgatattga tccagtcttt cgcatgttaa cagatgaaac agaaacgatc
     4081 ttgatgaagg aggatgtgtg ggacgagctg agagaagcac tttatgcaga aaatgatgaa
     4141 cgatttttcc aattaacaat gaatttttct aatgatcgtt cagatgacgg cttgacgaat
     4201 ctggtgtttt ctctttatga gtttgcccgt gccaaccctg acccccaaaa atggctagaa
     4261 cagttaagcg ataattatcg tttgcctgag gggctagcga aatctcgatt atatcaaaaa
     4321 caaatccgtc ctttagtttt ggcagatata taccaatgtg tacagttata tgaacagatg
     4381 actcagttag cacaaggtga aggattagaa aaaatgcatg agcaagtagc tggagaacaa
     4441 cagcagatca agaatatcta tgaagcgttc tcgcaagatc ggttagaaga agcttatgct
     4501 ggtttggaac aactaacttt ttcaactttt aagagcagtc ggaaagcaga attgaaagaa
     4561 atttccaatg aagtcaaggg catgagggat aaagcaaaaa aactgattca gcagataagt
     4621 aaaagttatt ttcctgtttc cccaagccaa atggaagaat taacggacaa agcactaccg
     4681 ttagtcgaag aaatgacaaa agtcacgcaa agcttcatgg acggtttcag tatgcgtaaa
     4741 cgggaaaaag gtgtgctgga tttcaatgat ctggaacatt tagcgttgca gattctcaca
     4801 gaaaaaacga aagatgtatg gctgccaagt gaagcttcaa aacattatcg aaaaaaattc
     4861 aaagaagtaa tggtagatga atatcaagac gtgaaccaat tacaagaagc cattttatac
     4921 tggctaagag aacccgatga tacaaaagga aatatgttca tggttgggga tgtcaaacaa
     4981 tccatctatt ctttccgttt agcagatcct agtttattta tcgggaaata cgagaatttc
     5041 tcaaagaaag aaggcggacg tcgaatcgtt ttggctgaga acttccgctc tagaaaagaa
     5101 gtcctttctt ttacgaatct tatttttgaa caactaatgg atccagcagt gggtcaaatc
     5161 aattatgacg aagcagccaa actgatccaa ggattttcag actttccaga gaatgaacag
     5221 tttgagccgg aaatcatgat ctatgaaaaa gaacaggaag aatcagagat tgagattccg
     5281 acggatgata tactggaaga caaaacagaa ggcgaacttt ttatgacagg actaaaaatt
     5341 cgtcaattaa ttgattcctc ctttatgatt tatgataaaa aatcaaaaaa aagtcgtccg
     5401 atagagtaca aagacattgt tctcttgaca cctacaaaga agaacaactt aacgatttta
     5461 gagattttca aaacattgga tattccatta gagatgaatg atgctcaaaa ctattttcaa
     5521 gcgacagaaa ttcgcacgat gatctcgctg ctacaattaa tcgataatcc ctatcaagat
     5581 attccgcttg cggctgtatt gcgctcaccg atcgtgggtc tgattgaacc agaattagcc
     5641 agcattcgat tagctaaccg tgcacatact tactatgatg ctgtgcttgc ttatcaagca
     5701 tcaaacgaag atgaattagc agctaagctg gaacattttg gcaagcaact agagcattgg
     5761 cgagaacttg ctcgccgttc ttcgatcact gacttgttat gggatatcta ttatgagacg
     5821 ggatatctag agtatgtggt cggtctgcca gcaggggcac agagacaagc caatctttat
     5881 gcattggttg atcgtgccaa agcttacgag caaagttctt tcagaggatt ataccagttc
     5941 gtgcgtttca ttgaaaaaat gcaagaaaaa gataaagact tagcagaacc agtcatttca
     6001 atagaagata atgctgttcg cgttatgacg atccatgcaa gtaaaggctt ggaattccca
     6061 gttgtatttt tgttagatat gacaaaggag ttcaacttac aagacttgcg caatcggtat
     6121 gcttttgaag aaaaacttgg agcaggaatt cgctatatgg atcctgaaac acgagtgtta
     6181 tatgatacgt taccgtttca agccatcaaa ttggcaaagc aaaacaaatt gttgtcggaa
     6241 gaaatgcgta aattgtatgt aggattgact cgggcagaac aaaagctttt cattgtcggt
     6301 tcctataaaa ataaagagca aatgatccaa acgtggtctg aagcagctga tcatgaggag
     6361 ttagtttttg atcctgcgct acgtttgaag ggcagaagca gcttgatgaa ttggattggt
     6421 tacggattga tccgtcatcc tgaaatgcag aaatacttag aggaagaaat ttcgacttct
     6481 cttcttcaac attcaaatgc acagttttct atttcatgga tgaatcagca atcgatcatt
     6541 gaacaaagac agttgcttgc tgaaaaagaa ctggttaact tagatcagca gatgaaagaa
     6601 gatgaaactt tattagcaga ttcgttacaa aaacgtctgg catatgaata tccttatcaa
     6661 gcttcttcac aaaccacaag ttatcaatct gtatctgaaa tcaaacgatt attcgaagat
     6721 ccagatgata cacaagaatc acgtttgact ctggaaagca gtcagaacaa agcagcatcc
     6781 cgtcaatttc gttatacgca agaacaacta gcagaaccaa aatttttgca aaaagatcgg
     6841 caagtgtcag cagctgctgt tggaactgct acgcatgctt tgttacaatt actgccatta
     6901 gagatgccaa ctacagagag tatccatcaa aaattacagg aattggtaag gaaacggtta
     6961 gtagacgaaa aagtcgcgaa aaaagtagat gtttcttcta ttatatggtt ctttcaaaca
     7021 gaacttggtc aacagctgat tgccaacaaa gaaaacgtaa aacgagaaca acctttttcc
     7081 atgctgcttc ctgctgacga agtatttcaa gactatccaa atcaagaaga tgaactatta
     7141 atccacggaa tcgtcgatgg atacctagaa gaaaaagatc atctcaatat ctatgatttt
     7201 aaaacagatt ttattttaca tccggatgat ccagcagaaa tagatgcaat cgtccaaaaa
     7261 tatcaaggac agctaagact ttaccaacaa gcaatgtcag aagctttgaa taagccagta
     7321 gaaaatgttt tcctaatttt gcttcgagtg aaacaaatta taaacattaa caaataatta
     7381 taattgagca aacttgactt atgttttgta aggattatgc tatactctgg gaagaggtga
     7441 gtatgatgga gctaacacag acagaattcg ttttatgccc taaatttgaa aaaacattct
     7501 ctattttagg aaaaaaatgg aacggattga ttatcgatgt actactcgaa aacggtccgc
     7561 aacgctttgt tgagcttgcg gcaaaaatcc cgatggtcag tgatcgagta ttagtcgaac
     7621 gcttgaagga attagaaaaa gaaggaatag tcactcgaaa ctttgcctgt agcgaaaaga
     7681 gccgttcaga atatctcttg actgaaaaag gagcagactt gcaaaaagcg atgcgtcaaa
     7741 tacaagtttg gagcgaaaaa tggatcacag aggaagaatg cggttgattt tgtaaaaaaa
     7801 atcttgtaaa ctatagtcca tacgaataag taaagaacga tgacgaaaaa gagtagtttg
     7861 gctaaaccag ttcagggaga tctgtcgcag actgaaagca gatcctgtgt ttgaaaaatg
     7921 aagttcactt tccgagttcg tctgataaaa tcagaccggc aattgtcgtt aacgaagtaa
     7981 gagtgcggtg taagtcattt atccgcaaat taggatggta acgcgaagac ctcgttcctt
     8041 aacaggaatg aggtcttttt gttttgtatt tggaatttaa aggaggaaca agcacatgtc
     8101 tctacaagca caattagaga gcttgaaaga agcaacgctc gtcaaaatca cagcggcaca
     8161 agatttaaat gaattaaatc aaatacgtgt tgaaacgtta ggaaaaaaag gaccgatcac
     8221 agaagtatta cgtgggatga aagatctaag tccagaagag cgaccaaaag tcggaagttt
     8281 cgcaaatgag atccgagatc ttttgacaga agagatcgag cgaaaaaaac aagtattaga
     8341 agaagaagcg ttaaatgcag ctttggcaaa agaaacaata gacgtgacac tacctggtag
     8401 aaaagtaaaa catggtacac gtcatatcgt gacacaaatc atggaagaaa ttgaagatat
     8461 ttttgtgggt atgggctatc agatcgtaga aggatatgaa gtagaatctg atcattacaa
     8521 tttcgaacgg atgaatctgc caaaagatca tccagcaagg gacatgcaag atactttcta
     8581 tatttcagac gagatattga ttcggacaca tacttcacca gtccaagcac ggacaatgga
     8641 aaaacatgat ttctctaagg gtgctctacg aatgatctcg ccagggaaag tcttccgcag
     8701 agatacagat gatgcgaccc acagtcatca gttccatcaa attgaagggc tagttgttga
     8761 taaaaacatc acaatgggcg accttaaagg aacattagaa gtcgtaatga aaaaaatgtt
     8821 tggggaagat cgtgaaattc gtttgcgtcc aagttatttc ccatttacgg aaccatcagt
     8881 agaagtagat gtcagctgtt tcaaatgtgg tggtgccggt tgtaacgtat gtaaatacac
     8941 tggatggatc gaaattttag gagctggcat ggtacacccg aatgtgttga agatgtcagg
     9001 aatcgatcca gaagaatatt caggctttgc tttcggcctt ggaccagacc gcgtagctat
     9061 gttgcggtat ggagtgaatg atatccgtaa tttctatcaa aatgacttac gtttcttaag
     9121 tcagttcaag ggggagtaag aaaatgttag tttcatataa atggctcaat cgttatgtag
     9181 atttatcgaa tgtaacacca aaagaattag cggataagat gtctgtgaca ggaatcgaag
     9241 tagagggagt aacggttcca gaagaaggct tgaaaaaaat cgttgtcggt gaagtcaagg
     9301 aatgcgtacc acatccagat tctgatcacc tttctatttg tcaagtcgat attggcgaag
     9361 acgaactgtc tcaaatcgtt tgtggagcgc ctaatgtgaa ggttggaatc aaagtgattg
     9421 ttgcacttcc taactcacgt atcgctggta atgtaaaaat caaaaaagga aaaatgcgtg
     9481 gccaagtatc aaatggcatg atttgctcat tacaagaaat tggctattca gatagtgtta
     9541 taccgaaaga atacgctgaa ggtatctatt atatgccaca agaagctgta aatggcgatc
     9601 cagtttttcc ttatttggat atggatgatt cgattattga attatctatc acaccgaatc
     9661 gtgcggatgc attgtcaatg cgtggcgtag cttatgaagt tggggcaatt tatcgtcaga
     9721 ctcctacatt cgatgacgaa aagctggtag aatcctcacg tcctgctagc gataaaattc
     9781 aagtggaagt tgaagataaa gaagcagttc ctgcttatca aatcagaatc attgaaggag
     9841 taagaatcca gccaagtcct caatggctgc aaaatctttt gatgaacgaa ggcattcgtc
     9901 caatcaacaa tgtagtagat gtgacgaact atattttgct tttattcgga caaccactac
     9961 atgcatttga ctacgacaaa ttgaaatcaa aagagatctt tgtccgccgt gcaaaagaaa
    10021 atgaaacatt agtaacacta gatggagaat ctcgggaatt gacaactgac aatctcgtca
    10081 ttactaacgg caaagaacca gttgctttag ctggtgtcat gggagggtta gactcagaga
    10141 tcacgaatga aacaacaaca gttgcactag aatctgcttt atttgatcca atttcgattc
    10201 gtcgtacagc aaaacaattt aatttgcgta gtgaatcctc tgcacgtttt gaaaaaggaa
    10261 tcaaccatgc gactgttgga gaagccagtg aggttgctgc agcaatgatc gtttctcttg
    10321 cgggtgggga agttctacaa ggcgcggtca aaggctcaga gatcaaagca gaagacgtat
    10381 cagtgaagat ttcacttgaa cgcatcaatc aatatttagg aacatctctt gtcgttaaag
    10441 aagtaaatga gatttttgaa gcacttggat ttagctatga agaaaaggag tatgtttatt
    10501 ccgtagtagt accaccaaga cgctgggata tccaaatcga agcagatatt atcgaagaag
    10561 ttgctcgtat ttatggatac gaccagttgc catctacact tccaagtgga gaaacggttg
    10621 ctggaagctt gtcaaaagaa caagaaacta ctcgtaaaat tcgtacaatc tttgaaggaa
    10681 gcggattgag cgaagcaatc agttatgcat tgacaacaga agaaaaatca agacagtttg
    10741 ttataaatga aagtaatatt acacgtttgg actggccaat gagcgaagaa cgttctgtat
    10801 tacgaatgaa tttgatcagc ggactattag atgatatcag ttataacact gcccgaaaaa
    10861 atacagagat tgctttatat gaaattggtc gggtgttctt ccaagaaaat gatccacgta
    10921 cacatctgcc gcaagaagta aaacatgcag caatcgctat ttctggtatt tgggaagaaa
    10981 aagattggca gacgaaagct caaaatgtag actttttcac catcaagggt cttttagaaa
    11041 acttatttga acaactaggc atcactgaag atgtccatta tcaaacagtg acagaaatga
    11101 aggaaatgca tcctggaaga actgctgcga tttaccttgg cgaaaaattt attggttttg
    11161 tcggtcaagt gcatccaacg attacaaaaa gttatgatat tccagaaaca tatgttgctg
    11221 agtttgattt atctgctata gtggaagctg ctcaaaaagg gatcgttttc gaagcagtga
    11281 caaaattccc agcagtcagc cgggacatcg ctttgcttgt aaaagaaact gtgacaaatc
    11341 aggaattaac agaagttatc cgttctgctg ccggaagatt tttaacagat atccaattat
    11401 ttgatgtcta tcaaggagaa aacattgaaa aaggacataa atccatggcg tatagcctga
    11461 cattcgtcaa cccagaagca acattgacag atgaagaaat caataaagca atggaaaaag
    11521 tcgaaaaagc gttggtagaa aacctagagg caagtattcg ctaagaagga aaatatagta
    11581 agtaacgatc aagtagcttt tgaagaccat acatttgaaa aaaagatgtg acacaacttc
    11641 gtcacatctc tttttttgat tttaaaaaag gaatagcaca gagacgagat aaaaaaacag
    11701 gcctttacag cctgcttttt tagagtaaat gaattaatgg aagtaattga ttcccattgc
    11761 tgattttact tcagaaagtg tttgtgcagc tactttagca gcttcttcac tacctttacg
    11821 taagatttcc ataacagctg aaggatcttt ttccaattct tctcggcgcg cacggatcgg
    11881 tgcaaattca gcttccaata catcaatgag gtatcgtttg atctttacat caccaagtcc
    11941 gccgcggcgg taatgagctt tcatttcttc aattgcttct ttatctgttc cgaatacatc
    12001 caagtaggtg aagaccatat tcccttctac ttgtccagga tcttgtacat ggatgtggtt
    12061 tggatcagta tacatactca tgactttttt ctgtaagaca tcggcaggat cggagatata
    12121 aataccgttt cctaacgatt tactcatttt gccatttcca tcgattccag gtaatctacc
    12181 cattcctttt ggtgggaata cgccttttgg ttccaccaag acttcaccat atgtatgatt
    12241 gaagctttgt acgatttcct gtgtctgctc tagcattggt ttttgatcct caccaacagg
    12301 tacaagattc gctttgaatg cagtgatatc tgctgcttga gaaacaggat agataaagaa
    12361 tcctgtaggc acgctttcac cgaatttttt ttgttcgatt tctgttttga cagtcggatt
    12421 gcgccgaacg cgtcctacgc tgactaagtt caaataatac atggttaatt cagctaattc
    12481 cggaatttgt gattggataa ataaagtaga ttttgcagga tctaatccca cggctaaata
    12541 gtctaaagca acttgcaaga catttgatga aaccttctca ggatttttag cattatctgt
    12601 cagtgcttgc atgtcagcaa tcatgacaaa cagttggttg tcttcatctg cctgcatagc
    12661 cactcgggtt tttagagaac cgacgtaatg ccctaaatgc agcttcccag ttggtcgatc
    12721 tcccgttaaa ataatatttt tcaaaaaaga cacctcttta cgatttgtaa gtctgagcac
    12781 ttaatatctt accgtttttc ctgaaaagaa acaacagttc ctaaggaaaa aacaaggaaa
    12841 gaggataaaa taactaatag attagaaatg gaagaaatat ttatgggaga ataaacgttc
    12901 taagaaactt tacaaattac taaactatca gatataatgt attttattat acatctttaa
    12961 aagaaatctt actaaataat aatgggagtg taattctatg gcaatgatta aatttgatca
    13021 cgtggataaa tattatggca agttccacgc attaaaaaat atcaatctcg aattcgagaa
    13081 aggagaagtt gtcgttgtca ttggtccttc tggttcagga aagagcacga tgcttcgctg
    13141 tatcaatgga ttagagacga tctcttcagg taagctgctg attaatgata ctgacttgca
    13201 tgataaaaag acaaaactga cagaagtccg aaaaaacatc ggcatggttt tccaacattt
    13261 caatttgtac ccaaataaaa ctgttctgga aaacatcaaa ttagcaccaa tcaaagtgtt
    13321 gaagcaagac caggcaactg cagtcaaaaa cgcggagaaa tttttgaaaa ctgtcaatat
    13381 gttagataag aaagattctt atccttccat gttatccggg ggacaacagc aacgggtggc
    13441 aatcgccaga ggtttagcga tgaatcctga gatgctgctg tttgatgaac ctacttctgc
    13501 tttggatccg gaaatgattg gtgatgtatt agacgttatg aaaaaattgg ctcatgacgg
    13561 tatgtcaatg attgtcgtga cacatgaaat gggctttgcc aaagaagtgg cggatcgtgt
    13621 tatcttcatg gctgatggag aagtattgga agacagcaga aatgtgagag actttttcga
    13681 aaatccaaat gaagtccgag cacagcaatt tatcagtaaa gttatcaatc attgatagga
    13741 ggaaaaagat gcgcaggtta aaaaaaatac gcctgatttt ccttttaggc attgcttttc
    13801 ttgcactagc cggatgtaaa ggaaatgggt tggcaaatga agatatttta gagcgaagca
    13861 aatctaccaa tgaaatcatc tggggtgtca agtatgatac tcgattattt ggaatgatgg
    13921 atattgagag cagaactgta caaggatttg atgtagatat tgcaaaagca atcactaaaa
    13981 agatccttgg tgacaatgga aaaacagaat ttgttgaagt cacttctaaa actcggattc
    14041 cattattgaa aaacggaaat atcgatgcaa ttattgcaac gatgacgatc acagatgaac
    14101 gaaaaaaaca ggttgacttt tcagatgtct atttcgatgc tggccaagct ttgttggtaa
    14161 agaaaggaag ccaaatcaaa agtgtagatg atttgaatgc ttctacaacg gttctagcag
    14221 tcaaaggttc tacatcggct gcgaatatcc gacagcatgc accagatgca aaaattttag
    14281 aattagaaaa ctatgcagaa gcatttactg ctttacaatc tggtcaggga gacgcgatga
    14341 ctacggataa tgcgattttg ttagggattg cagatgaaaa tccagagtat gagttagttg
    14401 gtggaacgtt tactaatgag ccttacggga ttgcgatcaa caaagggcaa gaaaacttct
    14461 tgaaagctgt taaccaagcg ctagaggaaa tgcatgcaga tggcacatac gataaaatct
    14521 atcaaaaatg gtttccaaat gaaactgaag gaaaagtaga gtaaggggga gaggcaatga
    14581 gcgaattgat acaaacttat ggaccaatct ttgtcgacgg gttcaagatc acattgtttt
    14641 cgagtgtctt agcacttgtg tttagtttga ttatcggaac gttaatggca atcttccaat
    14701 tatcaaagaa taaagtagtg agcgccttag caaaggcata tgtagaattt tttagaaaca
    14761 ttccattatt aatcatcgtg atgttttttt atgttgtcgt accgatttat tggtttaatc
    14821 tagatggatt ccaagcaggt acgattggat taacgatcta tacatctgct tttattgctg
    14881 aaacagtacg ttcagggatt caaaccgtac caaaaggtca aacagaagca ggactatctt
    14941 ctggttttac ctattcagaa atcatgcgtt atattgtttt accgcaagca ttcaaaatcg
    15001 ttatcccgcc attaggcaac caatttatca acctcgtaaa aaactcatct attttagcaa
    15061 tcgtagctgg tttagatttg atgtatcaag gagacttgat cgctagtgaa acattcaata
    15121 ccttcgatac gtatatcatc gttgggttat tttacttagt tatcacgcta ccgttatctt
    15181 acttaatggt ttatcttgag aaaaaatggg cggttcgttc atagaaggag gggaaataca
    15241 tggattttag cggcgctttt tcatggatga atatccgttt tttattggaa ggattaaagg
    15301 ttactgttga agtttcattg ttttcgatca tttttagttt cttgatcggt ggtctgacag
    15361 gtgtgattcg ttttgcgaat atccctttct tttccaaaat ccttggtgta gtgattgata
    15421 ttatacggaa tcttccatta ttattgatca ttttcttcac ttactttgcc ttacctcaaa
    15481 tcggcattca gatgaacatc ttctggtccg ctgtcgcagc attaacgatt tttgagtcag
    15541 ctatgttgtc ggaaattttc cgagctggac tcaatgctgt tccaaaagga cagatggaag
    15601 caggattatc aacgggactg acttatgtag aatcgatgcg aacgatcgtg ttaccgcaag
    15661 catttaaatc aatgatcccg gcaattgtga gccaattgat ttcactgatc aaagatactt
    15721 cattagcagt aatcatttct ttacctgaac tttctcatca ggcacgtatt atttatggac
    15781 agaacaccaa ttatgtgctt ccgatgttca tcatcatgac acttatgtac ttcgtggtat
    15841 gttacgcgct ttctctgctt tccggttact tggaaaagag acggtacagt tattaataga
    15901 tgattctttt agcggttgtg gcaaactaaa gtcacaaccg cttttcctct ttccattcga
    15961 aaaaaagaga tttcgattgt tttaagcaag taagagcact tgaaaattca cgctaaaaag
    16021 tacacaatag ggaggataga atttattgaa aaaaaggatg atacgattga cagataatcg
    16081 ccctatcgga tttattgatt caggtgtcgg cggcttgact gtagtaaaag aagccctgaa
    16141 acaattaccg aatgaaaata ttttatttgt aggagacaca gcacgctgcc catatggccc
    16201 tagacccgcg gaacaggtaa tccagtatac ttgggaaatg acggattatc tggtggagca
    16261 aggaatcaag atgctggtga tcgcctgcaa taccgcaact gcggtggctt tagaagaaat
    16321 caaagctgct ctttctattc cagtcatcgg tgtgatcctt cccggtacta gagcggcagt
    16381 aaaaaaaaca caaaataaac aagttggcat tatcggtacg attggtacgg taaaaagtca
    16441 agcttatgaa aaagcactga aagagaaagt accagaattg actgtgacaa gtcttgcttg
    16501 tcccaaattt gtttcagttg tcgaaagtaa tgaataccat tcatcggtgg cgaaaaaaat
    16561 tgtggcagaa acattagctc ctttaaccac taaaaaaatc gatacattga ttttgggatg
    16621 cacccattat ccattattac gccccatcat tcaaaatgta atgggagaaa atgttcaact
    16681 gatcgattct ggagcagaaa cagtaggtga agtatctatg ctgttagatt atttcaattt
    16741 gagcaattca ccgcaaaatg gtcggacatt atgccagttt tatacaactg gctctgccaa
    16801 acttttcgag gaaatagctg aagactggct tggaatcgga cacttaaatg tagaacatat
    16861 cgaattggga ggaaaataag gatgcgtcat gacgggagaa aagcccaaga gcttcgcaaa
    16921 ctggagcttc aaacaaatgt tttcaaatat ccagaaggat cggtagtgat ccgttttggt
    16981 gatacaacag ttatttgttc tgcaacaata gaaaattctg ttcccccttt tttgagagaa
    17041 acaggaacag gatgggtgac agcagaatat agtatgctgc ctcgagcaac gagtacgaga
    17101 aatcgtagag aaagcagcaa agggaaactt tctggtagaa caatggaaat ccagcgtctt
    17161 attggtcgtt ccttgcgtgc agtagtagac ttggaaaaat taggagaacg tagtatcatc
    17221 gtagactgcg atgtgatcca agcggatggc ggtactagaa cagcaagtat cactggggca
    17281 tttgtggcat tgaaattagc cattgaaaaa cttttaagag aaaaagaatt gtcagaagat
    17341 ccaataaaag aacatcttgc tgcagttagc gtaggaatct taccagatgg gacttgcgtc
    17401 acagatttgg attaccaaga agattccgca gcacttgtag acatgaatct tgtaatgaca
    17461 gaatctggaa aattcgtgga gattcaagga actggagaag aagcaacgtt tgatggtgaa
    17521 cagttgaatg aaatgctctt ttttggaaaa aacgcgattg aagatttgat caaagagcaa
    17581 aaacatgctt tgctaacaga gtttgctcaa aatgatgagc ggatagaaga aacaaaaaca
    17641 atcatcattg cgacaagaaa tccaggaaaa gcagaagagt ttcgaaatat gttcaaagaa
    17701 gcgggatatc atgtaaaaac attacttgac tatcctgaat tgccagatgt ggaagaaact
    17761 ggcagcacat ttgaagaaaa tgcccgatta aaagcagaaa cgattgcaca attgcttgat
    17821 cagccagtct tagcagatga ttcaggtttg aaagtggatg ctttaggcgg tatgccagga
    17881 atctattctg cacgttttgc aggggaacaa aaaagtgatg cggggaataa cgccaaatta
    17941 ttatatgaat tgacagatgt gccggatgaa aaaagaacag cacaattcca ttgtacgtta
    18001 gtattcgcgg cacccaaaaa agacagcctt gtagtagaag cggaatggcc cggtcgagta
    18061 gcccgtatac catctggcga aaatggcttt gggtatgatc ctttatttat cccagaaggt
    18121 aagaaacaaa cagcagcaga attatcgagc gaagaaaaaa acaagatcag tcatcgggct
    18181 caagcaatga aaaaattgag tgccgagtgg aaacaatggc tggaaggaga gagatagatg
    18241 cggtatttag tagtaagtga taatcatgga gacagagata tcctcgttga cttagtagat
    18301 cgttatcgtt ctgaagtgga tatctttttc cattgtggtg attcggaatt agaagcttct
    18361 gacccattat gggatacatt ccaagtggtt caaggtaatt gtgattatgg accaggattc
    18421 gaacagaaaa aagtgatcca aactggtcag gatacagtat tcatgactca cggtcattta
    18481 tcgaatgtcc gatttggttt gacacagtta gcaatcgaag ctcgagctgc aactgccgat
    18541 atggtgtttt ttggtcatac ccatcaaata ggctgtgaga tggatcagaa aatcctgttt
    18601 ttgaatcctg gtagcatttc tcagcctaga ggcccgatcc aaatcccatc atatgctctt
    18661 atcgaaagtt tagatgacca aatttctgtt caatactata accgtgccca tcaggcagtt
    18721 gaagagttgg ccttttcttt ttcgagagag cgctgaataa aaaaactcta atttttaata
    18781 aaaataagct ttattttatg aattttgcat ccggtttcgg taaaatagta gtgttgaatg
    18841 aaatagaaat ggaggccatc agatgattgg acctatagta agagaaatgc tgctggaaaa
    18901 tcaggaaacg tttttgattc ctgcagaaaa tgtggcaaat gttatgtatc atcatccatt
    18961 gtcccatggt ttacttgtgt tatcgaaggt cggttattcc aaaattcctg tattaggaaa
    19021 agatgatcac tttgtaggac tagtaagttt atcagatgtg gtcaataaaa tgattgactt
    19081 gcaaacaatc agcatggacc cgttagaagg actaacggtt gctgatgtga cagaaacaga
    19141 tgttccgaca attgatgaaa attgggaact agaagaagta ctccatttgt tagtcgattc
    19201 gcctttttta ccggttgtca cagaagatcg gattttcaaa ggaatcatta caagaaaaga
    19261 gctgcttaaa gccgtaaact tcatggtgca tgaattagaa cgtcgtaata tattgtctcc
    19321 gaaaatcgaa gaattaaaag aacaaatcga tatcgtgagc taaagaacga gaaactaaaa
    19381 gataatcaaa aaataagtag aaaaaacagc gtaccagttt tgactttatc ttgaaaaaga
    19441 ggctgggaca aaagcgttta actccaagaa ataagaagga attcacgaaa attgcttttc
    19501 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ccgtttatac
    19561 gtgtttagag cgtgggacaa aagtgttctt tacttttgtc ccacgctctt tttagtgaga
    19621 ttcgttgcat cgtttgtcca aattattttc cgacagcaat tggactgttc ggaatcgtga
    19681 aaccagaagc tgtcaattct ttgacatagg agctcaagaa ctcttctttt aaggcatatt
    19741 gttttccgtt caatgcgtag cagaccgtac gaatcgcaaa attgctgttt ccaagatcca
    19801 ctaatccaaa gatagaaggt tcagtttgga gctcttcttg gtatttttca gctaatgtac
    19861 gatttactcg atcaatgatc tcatagattt tgtcatatcc ttcttcagga acaatccgaa
    19921 tatctaaaag tacttgcata tttgcacgag agagattgct gatcgtggtg atgtttcgat
    19981 tcgggatgaa atggacagta ccatccgttg ctttcagctg aagggtacgg ataccaacag
    20041 atacgacggt tccttcaatc gttaagtttg ctagcttgat gtagtcccca acatccatct
    20101 gttgttccat gataataaaa aatccggtaa taacatcact catgaaccct tgggcaccaa
    20161 gaccgattgc cacacctgca attccggcac cagccaaaag tgatccgatc ggcacaccga
    20221 tagcagataa aattgcatag ataaaaaaga aaccaagggt ataatgaaaa atagtattta
    20281 aaagactatg taaagtcttt aagcggctct cgtttagaat ggctttttta gaatactgat
    20341 taaaagactt atcaatcaga tattttccca cacggtgaag aatccaaaaa aggacgatca
    20401 aaaaaatcag atataaactt ttttggataa aggcagccaa aatggcgtcc caatcaatcc
    20461 cgtcccaaaa ccgctgaaac gcatttactt tgctgacagc ttgatctgtc aatgtctcgc
    20521 cagaagagtc tgtcgtaccg gcagttgcta ataatgaaaa cataaaatcc tcttttctaa
    20581 aatttgattc tttctgtatt gtaccaagaa gttttcaaaa aaggaaatag caaaaataac
    20641 tataatgaag gaaaaaagct gaaaataaaa tgacaaataa tatggataat gataaaatgt
    20701 ggagaaaata acgaaggtgg taagtatatg caaatcgatt ggaacaatct aggtttttct
    20761 tatatcaaaa ctccttggcg ttttattgcc aaatggaaag acggacaatg ggaagaagga
    20821 gaattgacag aagataatta cctgacgatt catgaaggct ctccagcgct tcattatggt
    20881 cagcaatgtt ttgaaggtct aaaagcttat cgtcgaaaag acggcaaggt caatctcttt
    20941 cgacctgaac aaaatagtcg acggatgaat caaagtgcta gacgattgct gatgccaatg
    21001 gtccctgaaa agatgttcgt tgatgctgtc aagcaagtgg taaaagcaaa tgaagatttt
    21061 gtgccgccct atggaacagg cgctacatta tacttgcgcc ctttactgat tggggtcggt
    21121 gaaaacattg gtgtccatcc agctccagaa tatttatttg tcgtcttctg tacgccagta
    21181 ggagcgtatt tcaaaggtgg actaaaacca acgaatttta ttgtatctga ttacgatcgt
    21241 gctgctccta aggggactgg tgcagcaaaa gtcggcggaa attacgcagc gagtttactt
    21301 ccaggaacag aagcaaaaga actggattac tcagattgtg tttatcttga tccagccaca
    21361 catacgaaaa tcgaagaagt aggtgcagca aatttctttg gaattacaaa agacggaaaa
    21421 ttcatcactc cgcaatcgcc ctctatctta ccaagtatca cgaaatattc cttgttgcag
    21481 ttagctgaag aacgactagg actgcaagca attgaaggag atattttcat tgatgatcta
    21541 gatcaatttg cagaagctgg tgcatgtggt acagcggctg ttatttctcc aatcggtggg
    21601 atttatcaca ataacaatct tcatgtattt tatagtgaaa cggaagtagg accagtaaca
    21661 aaacggttgt atgatgaatt gacaggtatt caatttggag acatagaagc accagaaggc
    21721 tggattgaag tcgtggaata atttcaaagt aatgagttga aaaaaacgta aaaagaaaaa
    21781 atcaggaaga gactttaaaa agttttttcc tgatttttat atgttttact ttaaagaatg
    21841 caacaaaagt ttatgaaaga tggacacctt tgtcaacgta gataatatca ccgatgattc
    21901 cgctggaaag tgggctgatt aagaaagcac aagcattacc gacttcttcg atcgtcacac
    21961 cttgctgatc aggcgtacga gattcagata actggatcag tttttgatag tctttaacac
    22021 ctgtgacagc taatgttttg attgccccag ctgagattcc attgacccga attcctttag
    22081 gcgagaactc agctgccaaa taacggatag cagcttcaag agaagctttc gcaataccca
    22141 tcatgttata attcgggatt gcgcgttctg aacctagata agtcatgcta acgatcccgc
    22201 tgtttggtgc aagaaacggt tgtgcgtatt ttgatacagc aattaaagag tagctgctga
    22261 tatcttgagc taattgatag ccgtctctgg aaatatcaga cacatttccg gacaattctt
    22321 ctttgttggc gtaagcaact gcatggacaa ggccgtggat ctccccagca tattcaccga
    22381 tggcattcat tgctttttcg atgctttcgt cgctagaaac atcacattct acagtgaatg
    22441 cttcttcgcc gaccaatttg actaatgatt ttttcattcg ttcattttgg taagtataga
    22501 taatttctgc cccttgtttc aacattgctt cagcacaacc ccaagcaatg ctttttttgt
    22561 tagcgacgcc cataatgacg attttttttc cttctagaaa tgacataatg actctccttt
    22621 gtttctgata aa
//
LOCUS       DAFTHM010000038        22630 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFTHM010000038 DAFTHM010000000
VERSION     DAFTHM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.038"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            101..2542
                     /locus_tag="L7C88_001427"
     CDS             101..2542
                     /locus_tag="L7C88_001427"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBP9558264.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(2872..3576)
                     /locus_tag="L7C88_001428"
     CDS             complement(2872..3576)
                     /locus_tag="L7C88_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558265.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(3763..4008)
                     /locus_tag="L7C88_001429"
     CDS             complement(3763..4008)
                     /locus_tag="L7C88_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558266.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(4025..4876)
                     /locus_tag="L7C88_001430"
     CDS             complement(4025..4876)
                     /locus_tag="L7C88_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBP9558267.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            5042..6046
                     /locus_tag="L7C88_001431"
     CDS             5042..6046
                     /locus_tag="L7C88_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBP9558268.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(6287..6643)
                     /locus_tag="L7C88_001432"
     CDS             complement(6287..6643)
                     /locus_tag="L7C88_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBP9558269.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            7011..8198
                     /gene="tuf"
                     /locus_tag="L7C88_001433"
     CDS             7011..8198
                     /gene="tuf"
                     /locus_tag="L7C88_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBP9558270.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(8386..10977)
                     /gene="mprF"
                     /locus_tag="L7C88_001434"
     CDS             complement(8386..10977)
                     /gene="mprF"
                     /locus_tag="L7C88_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBP9558271.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(11003..11764)
                     /locus_tag="L7C88_001435"
     CDS             complement(11003..11764)
                     /locus_tag="L7C88_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBP9558272.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            12042..12563
                     /locus_tag="L7C88_001436"
     CDS             12042..12563
                     /locus_tag="L7C88_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBP9558273.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            12622..13482
                     /locus_tag="L7C88_001437"
     CDS             12622..13482
                     /locus_tag="L7C88_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBP9558274.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            13667..15982
                     /locus_tag="L7C88_001438"
     CDS             13667..15982
                     /locus_tag="L7C88_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBP9558275.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            16164..18005
                     /locus_tag="L7C88_001439"
     CDS             16164..18005
                     /locus_tag="L7C88_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBP9558276.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            18029..19138
                     /gene="rpoD"
                     /locus_tag="L7C88_001440"
     CDS             18029..19138
                     /gene="rpoD"
                     /locus_tag="L7C88_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBP9558277.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            19358..21457
                     /locus_tag="L7C88_001441"
     CDS             19358..21457
                     /locus_tag="L7C88_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBP9558278.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            21653..22516
                     /locus_tag="L7C88_001442"
     CDS             21653..22516
                     /locus_tag="L7C88_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBP9558279.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
BASE COUNT         7613 a         3970 c         4711 g         6336 t
ORIGIN      
        1 ttaaggattg ttaaaattta atcttagaaa aaaataactg gaacaagagc tatttgtttt
       61 tacagcaaag aatggtatat ttttgtagga ggtggcttac ttgaaagaag tcgttatgat
      121 agatgctgca agaacgccga taggaaagta tcgcggaagt ttaagtccat ttactgcagt
      181 tgaattaggc acacttgtga ctaaaggatt attagataaa acaaaactga aaaaagataa
      241 aatcgatcaa gtaatatttg gaaatgtcct gcaagctggt aatggtcaaa atgttgccag
      301 acagattgct ttgaacagcg gtctccctgt agatgtccca gcaatgacga tcaatgaagt
      361 ttgcggatct ggtatgaaag cagtgatctt agcacgccag ctgatccaat taggtgaagc
      421 agaacttgtg atagccggcg gaacagagag tatgtctcaa gcacctatgc tgaaacagta
      481 tcagtcagaa acaaatgaat atggtgaacc aatttccagt atggtcaacg acggattgac
      541 tgacgcattt tcaaatgcac atatgggatt aaccgcagag aatgttgcaa cacaattttc
      601 tgtgagcaga gaagagcagg atcgctatgc cttgtcgtcc cagttgaaag cagcacatgc
      661 tgtcgaagcc ggtgtatttt ctgaggagat catcccagtc aagatttctg atgaagacgt
      721 gttatctgag gatgaagcag ttcgtggaaa tagtacattg gaaaaactgg gcacgttacg
      781 tacagtattc tcagaagaag gaactgtaac agcaggaaat gcttccccgt tgaatgacgg
      841 tgcctctgtg gtgatccttg catccaaaga atacgcagaa aataataatc tgccttattt
      901 agcaaccatc aaagaagtag cggaggtcgg tattgaccca agtatcatgg gaatcgctcc
      961 aatcaaagcc attcaaaaat tgacagatag atcaggaatg aatttatcaa caatcgatct
     1021 ttttgagatc aatgaagcat ttgcagcttc ttctatcgta gttagccaag aactgcagtt
     1081 agatgaagaa aaggtcaata tatatggagg agcaatcgca ttaggccatc caattggtgc
     1141 aagcggtgca cgtatcttga ctacattagc ttacggattg cttcgtgaac agaagagata
     1201 cggtattgct tcattatgta ttggtggagg tttaggcttg gcagtcttgt tagaagcgaa
     1261 tatggagcaa acacataagg atgtgcaaaa aaaaaagttt tatcagctta cgccatctga
     1321 acggcgcagt caattaatag aaaaaaatgt attgacacaa gaaactgcgt tgatttttca
     1381 ggaacaaaca ctttctgaag agctctccga tcacatgatc gaaaaccaag tgagtgaagt
     1441 ggaaatccca atggggatcg cgcagaattt tcaaatcaat ggcaagaaaa aatggattcc
     1501 gatggcaaca gaggaaccat ctgtcattgc agctgcaagt aatggtgcaa aaatctgtgg
     1561 aaatatctgc gcagaaacac ctcagcggct gatgcgaggg caaatcgttc tatcaggaaa
     1621 atcggagtat caagcagtga tcaatgcagt taatcatcga aaagaagagc tgattctttg
     1681 tgcaaatgaa agttatcctt caatcgtgaa acgcgggggc ggtgttcaag atatctctac
     1741 tcgggaattc atggggagtt tccatgcata cttatctatt gattttttag tggatgtaaa
     1801 agatgcaatg ggcgctaaca tgatcaactc gattcttgag agtgtggcaa acaagttacg
     1861 ggagtggttc cctgaagaag agattctatt cagtatttta agtaattttg ctacagaatc
     1921 attggcttct gcctgttgtg aaatcccatt cgaacgctta gggagaaaca aagaaatcgg
     1981 tgaacaaatt gccaaaaaaa tccaacaggc aggggaatat gcgaagcttg acccttaccg
     2041 tgcagcaacg cacaacaaag ggatcatgaa tggtatagaa gctgtagtgg cagctacagg
     2101 aaatgataca cgtgcggtta gcgcttcgat ccacgcctac gcggcaagaa atggattata
     2161 ccaaggatta acagactggc agatcaaagg ggataaacta gttggaaaac taacggtgcc
     2221 tttggctgtt gccacagtag gcggagcttc caatatcctg ccaaaagcaa aagcatcttt
     2281 agctatgtta gatattgatt cagccaagga actagcacaa gtaattgctg cagtagggtt
     2341 agctcaaaac ctggctgctt tgcgtgcatt agttacagaa ggaatccaaa aaggccacat
     2401 gggacttcaa gctcgttcat tagcgatctc aattggggct attggtgagg aaatcgagca
     2461 agttgcgaaa aaattacgtg aagcagaaaa gatgaaccag cagacagcta tacaaatatt
     2521 ggaaaaaatc cgggaaaaat aaaaaagcaa tatctttaga agaataaagc aagatttaca
     2581 gttattttat ttactgcaga tcttgctttt ttctctatca gaaaatatgt ttattattag
     2641 aattttttat agttaaggtt aggcatctta agaaatcagg caactccaag atatcttcag
     2701 gtagaagaga agtcgcctaa cattgtagga tcataggtga tttgttggac aggtcaagct
     2761 gatatttgag cctgatgtta gaaggaattt ctttttactt gctgtagaaa ttattatatg
     2821 actaaaaagg ctgggatttt aaatcccagc cttttatgac aaatagaatt tttatcgatc
     2881 agtaatcgct gtcgctgcaa attgttcgat caaaggaatc aaagtcaatt tgactttgta
     2941 tttccgttcg agtgcttttt cgataacgaa ctcattttca gtagtcatag aaatagttgc
     3001 taatttacga ggttcatcag catttttttc attaataact acttcatgtt cattttgttc
     3061 tgtgtaaaat ttaggatact cagcaacggc ttttgaaaaa tcagcaaaac ttaaagcggc
     3121 attcgtatca gttgagcgtg tattttcagt tgtgtccgct tttggttttt ccgttttttc
     3181 ttctggcaca ctgactgttt cttctgtaac tggtgtcgca acagcttgcg cagttggttc
     3241 atcgtttttc aatcgttgat cattccagta agacacgatt tcaataagaa gattgtcacg
     3301 gaatcgttcg aaaatcccgt tttctcctga acgaattctc tttaatacag tattgaagtt
     3361 gtcatcgatt ggcacgttga tccgtgtatc ttcatttgtt ttcccagcta atccgatcgt
     3421 taagatttga cggtttttgg gatcaagcat gacttgtaac ggcaaaccat aacgtcgcaa
     3481 gctctcttct tctagagaac ggaataattg tcctcttaca ccatccaatg aaggacggaa
     3541 ttgatttaat aatttttgtt tctgtttttt cttcatatgt tctctccttc gctcataccc
     3601 tttcgattat aagaaaaaaa cagccaaatg aaaaggagta atgcaaaaaa acttgcgtat
     3661 acgcaaatta caacagaaaa atttgcgtat tttcccgttt tttgaaagaa aaataaaaaa
     3721 tggaacggat tatgtatata tacataatcc gttccattct ttctattttt tcggtatcaa
     3781 ggcaaaaaca ggtagttcag gtgaataaat gacttcatgt tcgtgccagg gtttgaccat
     3841 tagcgaatga tcgaaccgtt ttttcagttc ttcgatgatt tgatcatgtg tccagtttct
     3901 tgcaggaaaa tgttggattt tctctgcatc gatcaaaaag acaaaatcgg aatgaaaagt
     3961 ctgggtaact tcttccgaga gagaattcaa gcgttcgatt ggatccataa aatcaccttt
     4021 cgacttaaaa ttgggtagta tctgggtctt ttgctttgcc gactacacca tctaactgat
     4081 cgatttgttt catttcttct tctgttaatt caaaatcaaa taattcagta ttttctttga
     4141 ttctgcttgg tgtcactgac ttaggaagag gaaggaattc gtgttgcagc gaccaacgca
     4201 aagcaacttg tgcaatcgtc ttgtcatgtg cttcagcgat ttgtttcatt tcaggcacat
     4261 cgaagatttt accagtgcct aatggactat atgcttcgag gatcatatca tgtttttttg
     4321 catactcaac tacagttgtc tgtaattcgc ctggtgcaag gaaaacttga ttgaccatcg
     4381 gcataatttt tgctgttttt gctagtgtat ctagatggtg gggtaagaaa ttgctcacac
     4441 cgattgcttt gattttacct gcttcataca gttcttcaaa tgctcgccat gtatctgcat
     4501 ttgcttgttc ccaattatca cgaaaagcaa cagggtttgg ccagtggatc aaaaacagat
     4561 ctaaataatc tgtttggagc ttcttcaatg attcttcaaa agaagacatc acaagttcat
     4621 agctgtggtt tgcattccat aattttgttg tcaagaatat ctcttctcta ggaattccac
     4681 tttccttaat cgcttggccg acgctttctt cattcttgta tccttgggca gtatcgatat
     4741 ggcgataacc tgcagccagc gcttctttaa cagaggaaac agcgacatcc ccatcaggtg
     4801 tttgccatgt gccgaatcct actaccggga tttcgtaacc atttgataga cgataagtgc
     4861 ttgttaatga attcatactt tcagctcctt ttttattcgt tcaactataa gtgtagcgca
     4921 tttttcgaaa aaaagaatcc attttgtttc tactcttgaa atttttgttt aaaagaaaat
     4981 gattttgatt ctggtatttt tgattttttt tccgtaaact aagacagaag ggaatgagaa
     5041 aatggatatc tatttaaaaa aagcaattct gcatattatt gacagagaaa ctggttctcc
     5101 agtcttttca caaaaagagc tggatctgac aaaagaatat attcgtgatt ttcttcaaaa
     5161 gaagatccaa aaaatctctt ctgctcaaac aaaaactgga caactagcag aagaaagcat
     5221 gatcgttgaa tcacttaaaa tcgctcaaga aaattttgtg gaagcaagtg aagcaatcgt
     5281 tcagcggtgg ttcgatatct accaagaaag tgaagaagca cctagtgcag atgtatttgt
     5341 tgtcttgtat gaattagata cagtgatgta cttatcttta ttgaaagtca attatcgtga
     5401 ggcttacact cactttgttg aagcagacga agcagggatc gacaaccgct tgattttgaa
     5461 tcgagcaatt ctaggggcga aaacacaaaa agcagatgaa gcattcgctg tgaatttgac
     5521 tgattggacc tacgaattaa ttgaaaaaaa atatgagttt tctggcaaaa aagagcttta
     5581 tttttctgga agagtgatcg aaagtgttcc tgcaccttct ttagaagaaa atgtaaaagt
     5641 gatccaaaaa gtagccaagc atcttggaaa aaaatttgag acagaagaat ttgatatcat
     5701 ggctgatttg aaagaagctg tctatgatac gatagaagaa aaaggtcggt tggatcatga
     5761 gatgattgcg gaaaaagtct tcaaggaaaa catcacggca aaaatggctt ttaaagaaga
     5821 agtacaagag caaggatttg tcccagaagc acctcctgta aaagaagtac aagaaatttc
     5881 tgagaaaaaa tttggaaaac aaaaattcaa gctatcaaac gggatcgaac tgatcgtacc
     5941 agtagatgta tatcgcaacc cagatttgat tgaatttgtg aataatccgg atggtacgat
     6001 atccgtgatg atcaaaaatg tggatgaagt attgaatcgt ttataaaaat gactagaata
     6061 ttaggtgttc aagtaccagt gatcagttaa atgaattgtg tcaagagaag gatcggaaaa
     6121 gacgaatata acaaaaaaag agcgtgagac aaaagtaaag aacacttttg tctcacgctc
     6181 taaacacgta taaacggcgg aagcagaagc aactccttct tatttcttgg agttaaacgc
     6241 ttctgtccca gcctcttttt atctaataaa attttaagac catttactaa ttatcgattt
     6301 tttctgccgc atttttaggc acttcagaag cctttatttc ttcccagctt aatacacctt
     6361 tacgaggatt gactttgagt ttaagatacg cattcatctt taatggatgt tctctttctt
     6421 cgcgaagcgt cacctgtttt ttttcaccat ctttattata agccgcttgc ttgtaggtat
     6481 aagtcgtgaa tttctctccg ttatctgctt gggtagctga catttcgcca ttcgtcgtga
     6541 tttttgtata ataagcttcg ccgccgtaaa aataatgata agctgcaaaa cttccgccga
     6601 gaaatatgcc taaaacgaca agtacgccaa ttaatttttt catgtacttc acctctttcc
     6661 ttattattaa cgaaatagaa gatttcgtct attgaaagtt gttggcaaca gctgaatttt
     6721 aaacttttcc tcattttgtt cttattgctt caaaagaaag ttaaggacta tcttgaagtt
     6781 tttctcaaaa aacacatttt tttatttata aaaggtactt ttttcgcgta taagacagac
     6841 gagtgctctt agttgacttt gaccaatatt gacgtataat aagcttagtt cgaatcttac
     6901 aaaaagtaag tcggacgtat tctttttgat ttagtcaaaa aaagactata ataaaaaggt
     6961 gagagctgaa atttttcagt gatctatatt atttaggagg tttgtaaatt atggcaaaag
     7021 aacattatga cagaagtaaa ccacacgtta acattggtac gattggacac gttgaccatg
     7081 ggaaaactac tttaactgct gcgatcacta cagtattagg caaaaaaggc ctagcaaatc
     7141 ctcaagacta tgctagtatt gatgcagctc cagaagaacg tgaacgtggg attacgatca
     7201 ataccgcaca cgtagaatat gaaacagaaa aacgccacta cgcgcatatt gatgcaccag
     7261 gacacgcgga ctatgtgaaa aacatgatta caggggcagc acaaatggat ggtgcaatct
     7321 tagttgtttc tgcaactgac ggtccgatgc ctcaaacacg tgaacacatt ttattgtcac
     7381 gccaagttgg tgtaaaatac ctgattgttt tcttgaacaa agttgattta gtcgatgatg
     7441 aagaattgat cgatttggta gaaatggaag ttcgcgagtt attgagcgaa tatggtttcc
     7501 caggcgatga cactcctgtg atcaaaggtt ccgcattaaa agcattgcaa ggcgatccag
     7561 atgctgaagc tgctattatg gaattgatgg atacagtaga tgaatatatc ccaacaccag
     7621 aacgtgatac agataaacca ttactattgc cagtggaaga cgtcttctca attacaggtc
     7681 gaggaactgt tgcctcaggt cgtattgatc gtggtgctgt tcgtgtcggt gatgaggtag
     7741 agatcgtagg gatcaaacct gaaacacaaa aagcagttgt aacaggtgta gaaatgttcc
     7801 gtaaaacgtt agattacggg gaagctgggg ataacgtagg cgtgttgtta cgggggatcc
     7861 aacgtgacga tatcgaacgt ggacaagtac ttgctaaacc aggttccatt actccacata
     7921 caaaattcaa agcagaagtg tacgtgttga caaaagaaga aggtggacgt catactccat
     7981 tcttcaacaa ctatcgtcca cagttctact tccgcacaac tgatgttaca ggaacaatca
     8041 cattgccaga agatacagaa atggtcatgc ctggtgacaa cgtgacgatt gatgttgact
     8101 tgatccatcc aatcgctgtt gaaaacggaa cgacattctc aattcgtgaa ggcggacgga
     8161 cagtaggttc aggtatcgtt acagagatcg aagcataaga aacgcgactc gaatattttg
     8221 gtaatgaaaa atgtttaaaa taaaagagcg gtccaaacag gatttctgtt tggaccgctc
     8281 tttgttcttc aattgtataa gaagagattg tagaagcatg aactttcgtt ttacttcagt
     8341 ctcttttatt catcatgaga gtgttcatct atcggtatgc agtttttaat actttcttcg
     8401 tatccatttt ttcaaaccac ttattctacc ttgtgtctgc tcaactggcg cattatcaat
     8461 aatcagcaaa gcaatcataa catatgcaat ccaactatct ctagaatata gagtataacg
     8521 tgagacccag tttgtagcgt acttgctttt atattctctt aatccatgga aagaataaaa
     8581 atgagaacca aactcgtaaa ccaagtatgc aatcctttcc tgtaaaaaac tctttctgga
     8641 agttccgaca tttgaaagag gggccatccc taaattgaac cattggatat gttcttcttt
     8701 catataggca aacaaatgca agaacaagaa atccatactg ccagaaggtg cttttttaga
     8761 atcatatcgc atcagatcaa tcgttcctac tttattgttc gtgtaagtag gcatgatcgt
     8821 tgcaaaagcg acaatttctt cttgggtatt tttgacaact gcaataggcg ctctttgtag
     8881 ataatcttca gagaaaaagc ctaaagaaaa ccctttttcc tttcgtgaac ccaaccaatt
     8941 atcagagata tttttgaaag tactcatttg ctcagtagaa aatggtggtt gtaagacatc
     9001 aaatgtaaat ccttctcgtt cgatccgatt caagacagca cgagtgccct tcattttttt
     9061 ccctgaagtt gtaaaactat tcaggtctac ataagcttct tcccccatct taatgaaatc
     9121 gtagccgaat tcatgcaaaa tcataacaat ctcttcgctt gtttcgtaga aaactggtaa
     9181 atagcatagt cgatctgttt cttcgataaa agcttcgatt gcttctggaa aatcttcttt
     9241 cttaccagaa ggatcaccca ttacaataca tttattattg aagcaagcga attggagaag
     9301 aacagttggt tcaccgtctt tttcataggc aaacatccgc ttatctttta agaagatcaa
     9361 ttgactatcg gagtttcctc cataagttgt aaggatcttc agggcctttt cttcattaaa
     9421 ggcttcgcca atctgtttct tttctccttg aaggaaatga acaaatagaa cgatcatgaa
     9481 actaacagcg atgatggcca acaatcccga aaaccaaatc ttttcagaag gaaataagaa
     9541 aaaggaaata aaatggtgac gccgatgagg gaaatccggc agattgtata ccccaataac
     9601 gatgtaaagc aaggacagtg caccaataat gattccatcg atcgtacgcc actcccatga
     9661 atagatcaat tgttcccgaa ataattcgtt tttagaagca agaatgatca gaagcagaat
     9721 agacaagaaa accaccggtg tgaaactaaa atcacttaat aaaacataaa gtaaagctag
     9781 aacaatcaag aagattgtag gcaaatatgc tcgtttcaca cgtgctgcga tccctctgcc
     9841 cataatgatt aaaagaaatc ccaatagtat actaggaaat tggataataa aatgaaattt
     9901 caatgggttc aaactatgaa gccagcgaaa ctctgtaaaa gcttgcggga tagtggcaga
     9961 aagtactagc atgattccag aaaagtataa taagacaacc acgattttat gcgcaatttc
    10021 tgttgctaat tgtttaggga taccagaata acgctgatca aaagtggaac cgatattttt
    10081 gaagaaaaag acgattccaa tcaaaaacgg aatgatgtag tagaacaggc gatagagcaa
    10141 gatccacaca acgactattt ctcttggcac accaatagcg gacaacccga taatcatcat
    10201 tacatcgaaa ctcccaattt ctcctggaat catagacacg attcctatca ctgaagcagc
    10261 aatgaataat ggaattgttt gccacagatc aatccggatt tccattaaat aaccaacaga
    10321 aaggaaacta aacaggacac cggtccattc caacaatgaa actagcaata gctgtccttg
    10381 agttttaagt gaggtaccac caaggaatcc tttctttttg aaagtagtaa ataaaaagac
    10441 gacaggaaaa tatagaccgc cgccgatcaa ccatatccaa tattgcttca aaaaaggagc
    10501 aactggcgtg aagactacaa gtaaaaaaga aagcagactg taaatagaaa gtccagccat
    10561 caaaaacaag aaaactttcg ataatgcttg gatcacgttt ctgctctctt tcttttgtcc
    10621 atatagttca gagcgaagcc ccacactaac aaacccgccg aaaccggcaa tattgttgat
    10681 cgtattgatc agccagcttg tctcaaacag gtaacgagga ttctgctttt gttcaagcat
    10741 ccgattcaaa ataatatcat aaccaaccat aggtaacaca gagataagac caatcaatag
    10801 cattagtccg cttttccata caggtatagt ggcaaacgtt tctcctaatt gctggataga
    10861 tagagtttta ccgatggaca tcaattcacc gacaataatg acaatgacag aaatcaaaaa
    10921 gattgttttg aacagtccta ggtggttttt cagccattgt atggtatttt ttaacaaata
    10981 aatcaccttc tattcctaat agttatgttt cagaaagaaa ttgaagaact tctcgattga
    11041 agcgttcagg atcttttcta gctaattcat gtccttgttc tttcacaagc acaaaggaag
    11101 cttttggtat agttttagct atatacaaag aatgttttag cttgattaca tctttttttc
    11161 ccacgatgat caaagtgggg gagttgattt tttttaaatc attttctgta agcccgatgt
    11221 catgcagcaa aagtttgata actaaaagat ttttgcgaag acttgggcga aataaagaga
    11281 gtaaccatac ccatgcataa tgaatattac tgatgactct ggcagaaaaa cgaacgcctt
    11341 taacaagcgt gtttccagaa tttaaaatca atcgatgaac ttttttaggg aagctgctgg
    11401 caaataccag tgctagattt gctccatcac taaatccaag aaaatctgcc tgatcgattt
    11461 tttccagcaa catgatcgta ttcagatcct cggccattaa ctgaaaattc aacatagatg
    11521 cttcgtttgt cgaacgacca tgtcctcggc tatctactag atacacggta tagtagcgtt
    11581 cgagtacagg gacctgttct gaaaaaaagc ggccgctgcc gtcattgcca tgcagtaaaa
    11641 agagagggaa gccttgaccg ctcttttcat agtaaatttc gctcccatct ggcatttttg
    11701 catatttctt ttcttttttc acataatcac ctactgtgta aagtataacg attatatcag
    11761 tcattgggca attgttttta ctgaaaaaca acgatcattt tcgtaagatg tcaaaaaata
    11821 caggaaaatt cattttttct taaggcgtac acagaaatca aggaagaaat agccaagaag
    11881 ataaagaaat agtaagataa aaaaagatgt caaaataact aggtgatgaa atgaagcgaa
    11941 aacgattatc tattatccgt attctttttt acatgatcat tctgacggtt attggtgcgg
    12001 tgttgttttt atgaggaaga acttatcgtt cggtaaaacg agtggaaagc tatcaaatag
    12061 aaataacaac agctgcaaaa aattatcata tggaaaacta cgagaatttg atcaaggcga
    12121 taatattgac cgaatcaaaa ggaaaaggga cagatctcat gcagagctcg gaaagtctgc
    12181 atggagaagc tgagatcatt gataatccag ctgacagtat tgatcaaggt gtcaaatatt
    12241 tggcggaaat gatagtagaa gcaaagaaac aaggatgcga tttatggaca gctgtccaag
    12301 catataattt tgggaaagat tatattgcct atgtaaaaaa tcatggcgga gaaaacacag
    12361 tagaattagc agaagcgtat tctaaagatg tgctgagccc acttttagga aatgaggaag
    12421 ggaaacaata ccgatattgg cggatccagt ccttgcttta caatggcggc tatctctatc
    12481 ataatggagg taacatgttt tatcctgata ttgtcaaaat gaatgaaaaa ataatagaga
    12541 cctatgaaaa agtctttaag taaaatagca ggaaatgttc aatcatgaat aaaattaaat
    12601 gaaagaagga gtgcgcaaat agtggaaaaa aggcaaaaaa tggaaaatca agaagtgggg
    12661 tacacaacca aagactggat gttacggttt gtgaagggaa tgtttatcgg ttcaggattt
    12721 atcttgccag gagtcagcgg tggtgcatta gcagctgtct ttggcatgta tgagcggctg
    12781 atttcttttt tagcccacct tacaaaaaat ttcaaagaaa atgttttgtt ttttctgcct
    12841 gttggtctag gcggagtgac aggcatcttt ctactttctt ttttagtcag ttttttatta
    12901 ggtgcgtatg aaacaacgat attatggttt tttgtcggat gtatcgctgg aactgttcct
    12961 gcgttatgga aagaagcagg gaaaaaagga agagatactt ctgatgtgat catcatggtt
    13021 gttacttttg ttctggctta tttgttttta ttatacggcg ctcaattatt tgacgggcaa
    13081 gtcgatcaga attttggaac atggctgatt gccggcggat tgattggttt gggtatgatc
    13141 gtcccaggat tgagcccttc taattttttg gtgtatatgg gattgtataa agcgatggct
    13201 gacggattta aagaagtacg acttgaagtg attgtgccga tcggaattgg tgggattctt
    13261 tgtgttcttg gattgtcaaa aatcatggat tacattttct caaaggcata tagcaagcta
    13321 ttccatttca ttttaggtgt agtttttgct tcaacgatta tgatcattcc taccgattac
    13381 gcgggattgg gagttgctgg ggtactagct tgtcctgttc tttttatagc cggtacagca
    13441 ctaggttggt ggatgagccg tttggaggaa caatataagt aaagatagat tgataataaa
    13501 aacagcacac gggtgattca aacaaaaagg ttggcatctt ttttgtaaaa tcattcgtgt
    13561 gtttttctat aaattttata aaaacaagtt gtttttaatc ttggaacacg ctagacttaa
    13621 acacgtgatt atttttgaaa gttggcggaa aatggagaaa aagaaaatga atggacttac
    13681 acagcaagag gtagttcaga aaatggcttc tggccagcaa aatgactacc aggaagatgc
    13741 atcaaaaagt acaaaacaaa tattcagcga taatatattg acgttattca attttctgaa
    13801 ctttggtatt gggatttgtc tgttatttgt aggtgcgtat tccaacatgg cgtatttagc
    13861 aattattgtc gtcaatatcg ttattggaat ttatcaagaa atacatgcaa gaaatcttgt
    13921 acggaaatta tcgattgttt cccaatcaga agtactagtg atccgggacg gtaaagaaca
    13981 atcgatttct actaaagagc tggtattagg agatttggta aaaatcggag caggagaaca
    14041 gataccagcc gatttacagg ttatatctgg acgggcagaa gcaaatgaag ctcttttgac
    14101 aggcgaatct gatttgattg tcaaagaaac tggagctgaa ttgctttctg gaagcttttt
    14161 gacaagcggt tctgtcatgg ctgaagttat ccgagtaggt gcagataatt atgctgtccg
    14221 cttgactagc gaggcaaaga ctcacaaagc tattcgttct gaacttgtag attcgattcg
    14281 caaagtatcc aaattcacta gtttcgtgat tattcctttg gggatcatac tatttttgga
    14341 agcactgttc atccgcgatg cttctatcaa aatttctgtt attgcatctg cagcagcttt
    14401 gttaggcatg cttccaaagg gtttggtatt gctaataagt attgcattaa cgacaggggt
    14461 aaccaaactg gcaaaaaaac gaatccttgt tcaagacatg tattcaattg aaacgctggc
    14521 ccatgtcgat acattatgct tggataaaac agggaccatt actgaaggga aaatgagtat
    14581 ccagcgggta gaagcactac atccgctgta cgagaaagcc atcccagaaa ttatggggac
    14641 gtatctggca gaaagcagtg ataacaacat cactatgcgg gctatgagag attattttga
    14701 gctttctaat cggtatgatg tgacaaacaa agtcgcattt tcttctgatc gcaaatgggg
    14761 cgcgatggaa tttccagaac tgggagtcgt gtacgtagga gcgcctgaac gtttggtgga
    14821 agaagatcgg cttccggaca gtctaaaaac agcccaagcg aatggctatc gcgtacttat
    14881 gttggggatc gctccaaatc agcaattgaa cgaagaaaaa ccagcatttg ttgagccggt
    14941 tgctctgttt gaaatcgatg atccaatccg aaaaaacgct caagaaacac tagcttatct
    15001 tcatgaggaa ggtgtggatc tgaaagtgat ttctggagac aatcctttta ctgtctccaa
    15061 tatcgctaga cgtgcaggat taccgaatta tgatgcgtat gtcgatcttt ctcaaattac
    15121 tgaagaaatg gaagtgcgag aagctgctca tcgctatacg gtttttggac gagtgagtcc
    15181 gcagcaaaag aaattgctgg taaatgaatt gaaagaaagc ggcagaacgg ttgcaatgac
    15241 aggcgacggt gtgaatgatg ttttggcgtt aagagaagca gattgcagca ttgctatggc
    15301 agaaggtgat ggagcaacac gtcagattgc gaatctggta ttgttggact ctgattttac
    15361 tacattgcca gaagtcctgt ttgaaggacg ccgagtggtc aacaatgtga cgaaagtctc
    15421 aggcatcttt tttatcaaaa cgatttattc atttatttta tcgattatat gtgccgttac
    15481 agcaattgga tttccgttta tccctatcca aatcacgctg attgatttag cgattgaagg
    15541 gtatccttcc ttctttttat cttttgaaca agataaaaga aaaatcactt accgttattt
    15601 gcctacagca cttattaatg ctttaccaaa tgccttgctt gtagtagtga atatcattgc
    15661 ggtgtatcta cttggaaaaa cattcgcatg gggaaatgct gaaactacta ctttgatgta
    15721 ttacttgctg attgggatca gttgcatggc agttgtaaaa gcttgttatc ccttcaaccc
    15781 attgcgcatc ttcctagcag taacgacgat cgtagggata tatgtagctg caatgctgtt
    15841 ccatggaatt ttggaagtaa acttagggtt gggagagagc gtaggatact tctttgtatt
    15901 catgctcgta aatattgttc ttcgagtatt gtactggaag gctgatattc aaaatcagtt
    15961 actgaaaaga gtagcaaatt gatgcttaat gagatagaaa tgtgttatac ttgaaaaagc
    16021 aatgaaatat gatacaatca aacatgtata attgtgtcct ttaaaatcgc actgatttca
    16081 gttagtgcga ttttttaccg gttattctcc tgaaatatct tctgttaaac ccaaaagata
    16141 tcaatagagc agggggtgaa aaaatggctc aacggattcc tcaagaggtt atcgaaacag
    16201 tacgcagtca aacgaatatc gttgaggtga ttggacaata tgtccagttg aaaaagtctg
    16261 gtaaaaatta cttggggctg tgtccttttc atgaagaacg tacaccgtct ttttctgttg
    16321 cagaagacaa gcagattttt cattgctttg gttgtggtaa aggcggaaac gtgtttactt
    16381 ttcttcaaga actagaaggt ctaagttttc cagaagcagt ggtaaaagtg gcagacttcg
    16441 aacagatacc gttagaagat caatggcgtc agcgtactat agctgtccaa aatcctgaat
    16501 ctgctacggg gaaactgatt gctgctcatg aaaaagcagc ggaaatctat catcacatgc
    16561 tattgcatac aaaagctgga cagccagctt tagaatattt gcaaagtcgt gggttgtctt
    16621 tagaattaat tgaagaattc aacataggtt ttgcacctaa tgagcgttct tttcttcagc
    16681 aagtattcaa gaatgaatca atttcaaatg aattgttaga acgctctgga ttgtttgtca
    16741 cgcatgatga tggccgtatg tctgatcgtt tttatcaaag agtgatgttt ccacttcgta
    16801 attctcaagg ccagacgatc ggtttttcag gacgctggct tgcacctgaa aaagggcagg
    16861 aaaaagatca gcccaaatac ttgaatagtc cagaaacaga actgttcaat aaaagacaag
    16921 ttttatttaa tcttgataaa gcaagaagcg atatccggaa aaacggagaa attttgttgt
    16981 tcgaagggtt tatggatgtg attgctgcat ggcaggctgg tatcaaaact ggattagctt
    17041 ctatggggac aagtctaaca gctcaacaga tccaacaaat ggaaaagctg acgaaagaat
    17101 tggtcttttg ctatgacgga gacaacgcag gttttgaagc aaccaatcga gggattgaat
    17161 tgcttcggca aaacagtcga ttagcacttt ctgtcgtagt cgttccagaa aagcttgatc
    17221 ctgatgaata tctccgtaag tatggagaag catctttcca agaattagtg gctcatgggc
    17281 gcgaaacagt ctttactttt aaatcacgtt atttaaaaca agggaaaaat ttagataatg
    17341 aaaaagacaa gatcgaatac ctcgaagaat tactagttga acttagccga gttgtttcac
    17401 caatcgaaca agatatgtat ctatctcaac tgtcaacaga gtttcagatc ggcagagaga
    17461 cgatacaaaa acaactgcgc gatcttcgaa ggacaaatca gcaaaatcgt caagaacctc
    17521 aggaaagtca acacactcag gttacgagac aagaaactgc acggaaaaag agacctttga
    17581 cgcaagtaga aaaggcagag cagattctat tatatcgtgc atttaaagaa gtttctgtcc
    17641 gtaatatttt aaaagaacga gaatttcagt ttattcatga tgcatatgca gaagtttatt
    17701 ttttattcga tgcatatgtc tcacaacatt atgaattcaa ccttgcagag tttttagact
    17761 ttttgcaaga tgaaaattta aggcggttgg tggtggaaat cgaatattta ccggtggcag
    17821 aagaaagttc gccacgagaa atccaagact tgctagatgt gatcagcaaa tctggcttag
    17881 ctgatgaaat aacattaaaa aaacaaatgc agcaagaagc cagacgaact ggaaacaaac
    17941 agcttgagct tgaattgacg attgaaatca tcaatttaac gaaacagtta aaacaagcca
    18001 aatagctact caaggggggc cttcttttat ggcaaatgga acagataaaa aaacgtatga
    18061 agcagcagta gcagctttca tcaaagaaaa caaacccaaa cgacaagttg tatatgatga
    18121 tttatccaat cagcttgcta caccattcac tttgaatgca gatgaaatgg acaaattgat
    18181 ccaaaagatt gaagacgcag gtatcagtgt ggtggatgaa aatggtgatc catcaattca
    18241 cagcttgaag agtgctgaga aaaaagctga acaagcaaaa acagaagatc tttctgcgcc
    18301 aaccggtgta aaaatcaatg acccggttcg tatgtatctg aaagaaattg gccgtgtctc
    18361 ccttttaact gcggaagaag aagtagcgtt agcattgaaa atcgaagaag gcgaccaaga
    18421 agcgaaacag cgtctggcag aagcaaacct tcgtttagta gtaagtatcg ctaaacgtta
    18481 tgtaggacga ggcatgcagt tccttgactt gatccaagaa ggaaacatgg gactgatgaa
    18541 ggcagttgaa aaatttgact accgcaaagg atttaagttt tcaacctatg ctacatggtg
    18601 gattcgtcaa gccatcactc gagcaatcgc tgaccaagca cgtacgatcc gtattccagt
    18661 tcatatggtt gaaacaatta ataaattgat acgtatccaa cgtcaattgc tgcaagacct
    18721 tggaagagaa cctacgccag aagaaatcgg tgcggaaatg gatcttccaa cagaaaaagt
    18781 ccgagaaatc ttgaaaatcg cgcaagaacc tgtttccctt gaaacgccaa tcggtgaaga
    18841 agatgactct cacttaggtg atttcataga agaccaggaa gcaacaagtc cagcagaaca
    18901 cgcagcttat gagttactaa aagaacaatt ggaagatgta ctagatacat tgactgatcg
    18961 ggaagagaat gtccttcgct tacgttttgg tttagatgat ggccggacga gaacattgga
    19021 agaagtaggg aaagtatttg gtgttactcg ggaacgtatt cgtcagatcg aggctaaagc
    19081 attaagaaaa ttgcgccatc cttctcgttc aaaacaatta aaagatttct tagaataagc
    19141 gtggactatt gaccagaaga gaaatcagta aaactgtttg gtttatttta aaagaaaaaa
    19201 agcttgagac tacgcagtct caagcttttt tttctatagg aaggaaattc attcattatt
    19261 tttaagtaaa tcctaaaaat aagctattgg cgtgacgtat agaatatgat agattaaatg
    19321 gtagcgtaaa cctagtaaag gagccgatcg ctaagtgatg aaaaaatgtc caaattgcgg
    19381 atcgaaaaaa atggagcaga atactatctg tccagactgc ggtcatcaaa taactgcaga
    19441 agatcagcaa ataaaagaat caattgaaga aacaaataca gatgcagcta tgcaggataa
    19501 atcaactgaa gatgcagtct ttcctgatac agaattaaac gatccaatcg aatggtcgga
    19561 attgaaagat ttacctctag aatctgtaat ggaattattc gaaaaagcag aaccagaaga
    19621 cgaagaacca cctgctcacg atcaagtaac taatatagag aaaaatgaac agaagaaagc
    19681 aactgttcat gagacttcgg aagaatcagg aaagaatcaa gaagaaacgc ttgaatcaaa
    19741 acaaaaaaga agagtagctg aactgaaaga aatcgtcgat aatgaggaag aaaattcgat
    19801 actatccgct tatatcaaag cacatcgtga agatacaaaa gaagagcacg cgaaagagct
    19861 gctcaaaatg atcagtgaaa aaattgcaca ggaaaacaaa gtagagccag aaaaggaaca
    19921 agaaactgaa aaagactctg atagagaaaa cgccacaggt aaagaaacag taaaaataaa
    19981 agacgtaaaa acggatatca cagaaaaaac tgaagtattt actgaaaaac aattagaaaa
    20041 ggaaaaaacg aataaactgc cggaagcaga gaaaaaagaa atactcgaaa acacagacaa
    20101 aaagtcaaca gagcccgatg aaataaatag tgaatccgat gctgaaaatc aatctgtaag
    20161 caaagagggt actgatcttg aagcaaaaat agaaaaagaa gagaaccagc ctaagctgtt
    20221 tgaagcagaa gcgaaatcaa taacaatcgt gccagatact gaaaaaacac atcaagaatc
    20281 aaacttagaa aaaacagatc cagataaagc gcaaaagaaa aaatcaaaaa aagtacctta
    20341 tctcgtttta gcagcagtac ttctactcgg tggaggaagc tgggcttatt atgaccatca
    20401 tcaaaaagta gaagccgaag tagcagcaga agcaaaaaga cagcaacaaa tggaagaact
    20461 tcatgagaaa cttgctgcct tttatacaga tgatcaccat caatttattc gtgcagatat
    20521 gattcatcaa gatttatcaa aactaaaaaa tgatttatcc agtcttaaga atgaaaaagg
    20581 atattcagag ttagaaacaa cttaccaaga tatccaatct aagatccgag atatccaaaa
    20641 agtgaatgag tggttcatag cacctgccat cgtcgatgat catctagcag atgacatcaa
    20701 gttgaaagca gataaagaga tccaagcaat cgaaacggat aacacagatt ttggaaaatt
    20761 gattcaacaa gcacaaacag aagctaaaaa tcaatatgct gaattgcaaa cagctaaaga
    20821 aaaaacagct atagtcttta aagacggaaa agtagtggat tcagcaacac gcgaccaata
    20881 caagacggca aaagaagcag tagaaaaagt gaaaaataca gatctatctg ctcagttgaa
    20941 tgaacaattg aaacaagtag ataagatgct cactgataaa gagaaaaaag aagaagagga
    21001 aaagaaaaaa gcagaagaag cgaaaaaagc agctgaagaa caagcaaaac aagccgctca
    21061 agcagcagct gcagctcaag ccgctcaaca agctgcggtc gcacaagcag cacagcaaga
    21121 agcggcatcc tcgacccctt cctcttcaaa ctcagcgaat cagccaatca aatctgccag
    21181 agcaagtgat attgccgatg catctaatcc agcatggacg tgggcaccag gtgtccaaag
    21241 caaagtgatt gctacatgta tccaacgtgg atatatcgtt gaaggaggtt acagattaga
    21301 aaaagccaga atcgaaaatg gggaaggcta ttataatcta tatgccactt caacaaaatc
    21361 tgcattgatg aaaggcattg gagaaagtgc tttgccattt tacatcgtaa ccatcaactg
    21421 taaaactgga tggttcggag gaaatgggag caattaattt taggcaaatg aaagaggctg
    21481 tgagcctgcc gtttaacacc gtttattcga aaaaggggag tatgacacaa ctgttgtcat
    21541 actccttttt tcacctttcc aaaccaaggc tcagctattc aagtagataa cattatgtta
    21601 tgatagcaaa gaaatgtatt aagaaaacct ttcactatag agggagaaaa aaatgaacga
    21661 tttattagca actatattta caggtattat tattgatgaa aatgaaaaaa actactttgt
    21721 ccaaaaaaac ggacaaacct ttggcttaag caaatcagaa ggtgaacaca aaatcggtga
    21781 agcagttgaa ggattcggtt accaaaatca aaaacatgaa aatcggatca ctacacaaat
    21841 tcctaaaagc cgtatcggtc attacgcttt tggaatcgtt actgctacac gaaaagattt
    21901 aggtgcgttt gtcgatatcg gtcttccaga taaagacttt gtcgtatctc ttgatgaatt
    21961 gccgacaatg acagagctat ggcctaaaaa aggggatcgc ttgatgattt cccttagagt
    22021 tgatgcaaaa gaccgtattt ggggcagttt agcagatgaa aaaatattca aatctttaag
    22081 caaatatgga acagaagaaa tgaaaaacaa agatgtgata ggaacagcat accgcttgaa
    22141 attaacaggt acgtacgttt taacggaaga tttctatctt gggtttatcc atccttctga
    22201 acgatataat gaacctcgtc taggcgagca gataaaaggt cgagtgattg gtgtccgacc
    22261 agacggtgta ctgaatcttt cattgaagcc aagagcatat gaagctatat cagatgatgc
    22321 acaaatgatt ttaaccattt tagaacgttc tgcagatcag caaatcaact ttacagataa
    22381 atcggatcca gaagaaatca tgaaagcttt tggtatcagc aaaggagcat ttaagcgcgc
    22441 attaggtaat cttttgaaac aaggattgat tacacaagaa aacggtgtga caaaactagt
    22501 caaaaaatct aattgagaat cccttgcatg tttttcttaa ctagcttata ataattttaa
    22561 ttaacatagt gttatatctt tttttatttg taattattat aaattgttgg ggttgagtaa
    22621 atggtcatga
//
LOCUS       DAFTHM010000039        22026 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFTHM010000039 DAFTHM010000000
VERSION     DAFTHM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.039"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(61..1371)
                     /locus_tag="L7C88_001443"
     CDS             complement(61..1371)
                     /locus_tag="L7C88_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBP9558280.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1383..2801)
                     /locus_tag="L7C88_001444"
     CDS             complement(1383..2801)
                     /locus_tag="L7C88_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9558281.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3041..4609)
                     /locus_tag="L7C88_001445"
     CDS             complement(3041..4609)
                     /locus_tag="L7C88_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBP9558282.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4613..4894)
                     /locus_tag="L7C88_001446"
     CDS             complement(4613..4894)
                     /locus_tag="L7C88_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBP9558283.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4891..5814)
                     /locus_tag="L7C88_001447"
     CDS             complement(4891..5814)
                     /locus_tag="L7C88_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBP9558284.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5811..6689)
                     /locus_tag="L7C88_001448"
     CDS             complement(5811..6689)
                     /locus_tag="L7C88_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBP9558285.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6676..8013)
                     /locus_tag="L7C88_001449"
     CDS             complement(6676..8013)
                     /locus_tag="L7C88_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBP9558286.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8016..9119)
                     /locus_tag="L7C88_001450"
     CDS             complement(8016..9119)
                     /locus_tag="L7C88_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBP9558287.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9193..10701)
                     /locus_tag="L7C88_001451"
     CDS             complement(9193..10701)
                     /locus_tag="L7C88_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBP9558288.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10667..11359)
                     /locus_tag="L7C88_001452"
     CDS             complement(10667..11359)
                     /locus_tag="L7C88_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBP9558289.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11381..12355)
                     /locus_tag="L7C88_001453"
     CDS             complement(11381..12355)
                     /locus_tag="L7C88_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9558290.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12655..13527
                     /locus_tag="L7C88_001454"
     CDS             12655..13527
                     /locus_tag="L7C88_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9558291.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14109..16307)
                     /locus_tag="L7C88_001455"
     CDS             complement(14109..16307)
                     /locus_tag="L7C88_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558292.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16539..17531
                     /locus_tag="L7C88_001456"
     CDS             16539..17531
                     /locus_tag="L7C88_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9558293.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17591..19012
                     /locus_tag="L7C88_001457"
     CDS             17591..19012
                     /locus_tag="L7C88_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBP9558294.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19005..20504
                     /locus_tag="L7C88_001458"
     CDS             19005..20504
                     /locus_tag="L7C88_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBP9558295.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20543..21937
                     /gene="uxaC"
                     /locus_tag="L7C88_001459"
     CDS             20543..21937
                     /gene="uxaC"
                     /locus_tag="L7C88_001459"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBP9558296.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6669 a         4495 c         3823 g         7039 t
ORIGIN      
        1 atcattaaaa aaaataaagg tcaagctaaa atattattta agcttgacct tattataatt
       61 tcaacgattg tcaaaagtat tgtttgcagc tgtgttgcca gtttctatag ataaatcaca
      121 gcttttgaaa cataagtttt gtactgcttc gattcgcccg aattcttttg cagttatttg
      181 gcaatgagaa aagcagacat cttctatagg cttttcagga aatgctacta aatcaaaagc
      241 tcgggaagga agtgagtaac ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc
      301 tttgactttc gtcatttgct ttgattcagg tatttcttca gccactgctt gccaactttc
      361 tggcatttga gcaaggtcat tgctattttt tctattgtat tcattatgcc agtccattat
      421 ccaagaaaaa ggaaattgta catcaatcat attcagattt tctaccctga tattttcgat
      481 cactccccct ctttcttttg aagatttcat tcgaatacca cagtctgact gaaaaaaatt
      541 gatatcgtga atatatacgt cactaactcc agcactaact tcgctaccaa tagttacacc
      601 gtatcctgaa cggattttac atctagcaac ctcgattctt gatgattttc gattgactct
      661 tgcaccattg ccatctctgc cagacttaat agcaatacaa tcatcaccac aggccaaatc
      721 acattcatag acacgcacat ttgttgaaga atcaatatca atcccatctg tacttggtcc
      781 atcattgttg cggatgatta ctttttctac taatacatcg ttagaataag tgatttgcaa
      841 gttccaaaaa cctgatttct gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata
      901 cagtaaacaa gcgcgtggac gtttaatagc ataatccgca atccaacgaa gtcccttttg
      961 atcgtattca gctcttgtcc cgcttttttg atcttttccc caatacagct cccaccaatg
     1021 gtctccttga ccgtcgatta ttccttttcc ttctataaga atatctttcg ccgagagaac
     1081 attcaaaatc gctgctggcc atttcatttc tacgccggct actcgtgtat cgatttctgg
     1141 aaatgcttcg atatctgttc tccccttgag gactgcacct tcttcaaaga taagatgact
     1201 cttatctttt aaaaaaaggg ctccgactaa ataaatgcct tttggaataa atacaggtaa
     1261 gtgttctttc gcaccttgat cgattgcttt ttgcagtatt attgtatcat cttgttgagt
     1321 gtcgtttgtt ttaaagttca aagcattgat aatccctttt tttgtccgca atacgtttct
     1381 ccctatcttt cattgatttt tttcaattct tcaccaataa atacagtttt tgaacgattc
     1441 agtgggtaac ctactagcaa aatgattgcg gatacaaata agcagaatgc tggtaacaag
     1501 tttgccatcg tataaatcct ttcttgtact aaaactgatt ggatggctcc acctgttgta
     1561 gacgattggt aaccaatgag tgccagcata aatccgccta ccgctcctgc acatgcttgt
     1621 cctacttttc tcgcaaaaga atttactcca tatactgttc catcttctct taagcctgtc
     1681 ttatattgat gataatcaat cacgtcagta atgaatgccc agaccatcaa attgaataaa
     1741 ccagatccta aagtagcgat aaataaaaga atcagatata cccatgcatt tgttatatga
     1801 aggaaataca tcagcaagta catacatgaa gaagcaagta acgcaaatac gcttgcttcc
     1861 tttttaccaa ataattttgt cagctttgta gcaaatggtg ctaaaactac tactgttccg
     1921 taagtaaata aaagagcaac agacattgct tgtttattat ggaagtaatc attgaataaa
     1981 taagtcatat tcgtcccagc taaaatctga ttgatcacaa tgaaaatgtc aacaatgact
     2041 aaaataatca gtgctcgatt agctaacaaa ccttttacca actgagaagc agatactttt
     2101 tcgtttttga caactcttac tctttcagta gtcaatttac aagttaacat atatgcgaca
     2161 aatgctattg cagcacatcc gattgaaatc caaaagaaat gattccctga aacgacttgt
     2221 tgtccactct tgttatgggt atacattaaa atcggaatga agaatcctgt agttgatccg
     2281 ccaatcgcag aaccaatgct tcggaacgtg gacaacgagg tgcggtcatt aggatttgag
     2341 ctaattgctg ctgccattgc tccatacggg atattgattg ttgagagaaa aatcccataa
     2401 acaatgtatg aaacaaaaat ataagcaatc ttcaccgtca ttggaagatg ttggacgaat
     2461 ggcaaaaaca aaatgacagt cactaagcaa aatggatact tcatttttct gatccaagga
     2521 ataaatcggc cagtttctgt taactctgag acatcacata atcttccaac catcacatca
     2581 gcaaacgcat ccaaaattct cgaaatcaag aataacgtac ctacgattgc ccctgaaacg
     2641 ccaagaacat tcgtataata aatcatcaag aaactattga ctaaacctaa aataaaacag
     2701 ttacctagat caccgaacat gtagcctatc ttatcggaaa tcccaaattc ctttttttct
     2761 ttttttactg tatttgctgt aacagcattt tgtgaaagca tttgaattcc tcctacctct
     2821 tctagtaaac gttttcaaaa ttataactct ttttttcttg tttttatatt cacaatgttg
     2881 gctttttatt gcattatctt gacagataaa aaacaaaaaa taatctaaaa acattgatgc
     2941 ataagattga taactttttt tacataacaa tatatacaaa caaaaaaatt cactaactag
     3001 tgaaaataag ttagtgaacc tcatttatta aagaattaaa ttacagatga tcttttccat
     3061 catacttgaa aaactcaaaa tcagcataac ttcctctttt tttatttaga tcatgcactg
     3121 ctatcccgat aaaatttcca gtaaaccctc ctgagagtat acacatgttt ttttgcggac
     3181 ctactttctt ccattcttca gttgatacgt ctttcaaatg aaactgtgct gtctctttct
     3241 ttacagtgac tttcaaaaaa gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt
     3301 gtgctactcc gttttctgat tctatcatac gtaggcattt tcccttgtcc tcattccaag
     3361 taacataaca ataaatataa ttggattcat ttaagtacag taccagtcca gccatctgat
     3421 taaaattatt aggcatgtat tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc
     3481 gaatagctaa caaatgatgt tcgaaggtag attgaagaga ttcaccggaa atcagacgta
     3541 aaaaacctgg tctacatttt gtatcacacc aatcagcatt tggcaaaatg cgtctggcat
     3601 tccagttctt ctttagctct ccttcaaatg tatccataaa ctgatgatct ttttcttgtt
     3661 gtacctcttc atttgtctca atcattattt cttccatcgg agttgtctgg ctatctttaa
     3721 gtcttaacca atcgtcggac gtccaataca cttcttgaat agcggtttct cttcccaaaa
     3781 tagccgcacc gtttaatggt ctggtacaaa gatatgtcat gtaccatctt cctgacgggg
     3841 tttgtactaa gctcccatgt cctgtacatt gcaatgtaga agcaggtttg tcactagctg
     3901 tcagcatagg aaaaccagga tcaagctcgt aaggaccagt aatattcttt gctcggcaaa
     3961 ctgtaactga atgtcctctt cctgtaccgc cttctgccgt catcaaataa taatacccgt
     4021 tacgaaaata caaatgtggt gcctccgttt tcgctaattc tgtacctgca aatattttat
     4081 agatgggacc atcaagcttc ttcttctctg catcatattc ttgtaatacg ataccgctgg
     4141 atttattcgg tgtgtccaga cgataatccc atagttcatt gacaagccat ttttttcccg
     4201 tttcaagatc atggaacaaa gaaggatcaa agccgttact atttaaataa attggttcgg
     4261 accaaggacc tgtgatctca gatgcagtga tcaaataatt gtggacatct ttaaacggac
     4321 ggcctgcact tttgacatct gtgtaaacaa gataaaacaa tccatcagca taactgatct
     4381 gtggcgccca tatacttcca tttgtaggat ttccttgcaa agatacttga gtggtcaaaa
     4441 tatccgttgt atgtgaccag ttgactaaat ttttcgactc atatactcgg attcctggaa
     4501 gccattcaaa agaggagaca ataatgtaat accgctcttt cactcttaat atattaggat
     4561 ctggattgaa tcctcttaaa ataggatttt tcactttgat agtctgcatg attcaggctc
     4621 cttttctcat tcttactcga tataaactga atgccccagc tgctaaaaaa gcaagtgaaa
     4681 taaacaacac aacggcaaac agaccagtca tgtcctgtaa taatccaaat gtattttcta
     4741 aagacaaagt tgaatgatct acagcaagcg actgataact ttttttaaac tctgacgcag
     4801 acatattact taaagtaact gctaacccgc caaagaaaat caaagataga ctgccaccga
     4861 ccattcctag caatagttcc cattttcttt tcatttctga accccctgct tttctaaatg
     4921 tatccattca ggtcttttga tcgatgtttc ataattgtta ttacgttcag agaatttgac
     4981 agtctgttca tttttcttgt catcccaatt atcccaacca gttgggtgaa catgcccacc
     5041 tatcttacac gcttcaaata agacatttgc atacggacgc cacggtcttc ctaaatagac
     5101 gtttctagta tcaggttctg cagtcaaggt acagctttca aaacgatacc ctgttttttg
     5161 atttttcggc gtagatgctg ctgtgatgta tccaggattt ttactggcta agctatggat
     5221 atgacactga tgaaaaacgg catctgcccc accaaatatg aaatccaccg ttccttcaat
     5281 ccagcaatat tcataggtct gacgacaata ctcaggattg gcagaagccg gtgtacaaaa
     5341 aggagtacca tctttttgca aatcaggcaa cggacccgtg cataaggtat cctgataacc
     5401 agatagtcga cagtttttta aagatacgcg atctcctgaa ttgaataaag caacagcctg
     5461 tcctaccttt tctcctggac ctgctgtatt ttcgatgtga agattttcta atacgacatt
     5521 cgatccttct aagaaaaaag tagcacttcg gaaagtccct aactggctac cgtcaagata
     5581 ctcctgtttt gcaaaacgat taccggagat aactactgtt cctgctccca caagtttaaa
     5641 attggataat ctgctttcta tatattcatc atatcttcct tcttttacta tcaagacctt
     5701 tggatggcta tccggcaggc ctgccaaata atcgattcct tcttggatag tttcaaaatc
     5761 cgtcggggta tctatagcat tctttccaat tatcagtttg tctttcatcc tcataaatgc
     5821 tcccttatga attgtttcca aatatttctc atttcttgtg tttccatatg accgcctgtt
     5881 aaagaaaaag aagaaaagtt ttctggacta cccattgatt gatacttttt gtccagccct
     5941 tttctcagct tcagtacgcc ttcgtccaag cacatcgtat cgttttttcc aactaagcta
     6001 agacgagggc gcggagcgat tttttcttgg attgctaacg ttgtataagc tgtcaataga
     6061 tttggcacat agtaataaaa cccatgatga tctaggcggc gatgtagcaa aagtgtttcg
     6121 atgtccacct gtgccgctag atcaatacaa actttgacac gagaatccaa tgctgtcacc
     6181 caccagctta ataagcctcc catagaaaga ccaatcgttg cgagccgttg agtatctgtg
     6241 tcttcccttg tctccaaata atcgatcaag ctgatcacat cataaatacg cattccccat
     6301 aacgtttttc ctgttaataa aaattgtttg aacaactcgc tttcagaaat acctccgcgt
     6361 tcttcaaatc cccaagcatc aatcgaccaa acagcatatc ccattcctgt cagtacttct
     6421 gcaaaagatg gagaagctaa gtaaggagca ccatggatca attcactttt cccgactgaa
     6481 aaatctccgc cgtgagaatg caggtaaagg accgtcggaa acggtccttc tttttctgga
     6541 taagcataga gggctggtac tgtttccaat tcatttaagt acaattgata gtattcaagc
     6601 ataaaaccgt tttgtttttc tcggtataat cgttttccac taggggtatg tctgctagat
     6661 ggagcaccta aaaaatcatt caactgcata agcaaagttt ttacgaacaa ccagttcatc
     6721 catattttct gattgatttg attggaattt ctcaatactg atttctttag tattttctaa
     6781 tagaaatgct ggtccctcgt gattttcaat cgacatctgg ttaaaggaaa ccttacccgc
     6841 aaagccaata taaaatcctt gtctgctcat ttcctctatt cctgtcatca tagcaggaac
     6901 accgggaact gcatcttggg ccatcgagac atcgatattg tcaaatgtga tttcttgtat
     6961 gaattgttcc gctaatccat aaataaaacc tgcagaagca tggacattcc ttgccgtgat
     7021 attcgaaaaa tggatccttc tgaatgctga tgtccgttca tctatcggat aagccttttt
     7081 ttcccataca tacggttctt tccctcgcgg accacagaaa taataaagat tcagtataaa
     7141 tggacacatc acattatcca tgactatatt ggatactcga atatcttcaa cgatcccgcc
     7201 tcgacctcgt ctagatttca atcgtattcc tcgatcagtt tcttggaaga tacaatttga
     7261 aatggtaata ttacgaatac taccactcat ttcacttcct aatacgacac cgccatgtcc
     7321 atggaccatc gtgcaatttg tgatcgtgat attttcgcaa gcgatccttt cgtacgtatc
     7381 ttcagtccct gccttgattg caatacagtc atctcccacg tcaatatggc aattactaat
     7441 acgcacattt ttgcatgatt ctggatcaat tccgtctgta tttggtgaat ccgctgggtt
     7501 caagatcgtc aagttatcaa acgttgcatt actgcaaaga atcgggttga tcgtccaact
     7561 tggtgactgg atcaatttaa tatctttcac agtaattcga tgacagttat ggaaactcat
     7621 caatttagga cgaggataag cgagattatc tggttcattt ctaaaagtat gccaccattt
     7681 ttttccattt ccatctaatg taccgaaacc agtgacagag atgttctcta cattttgagc
     7741 atagatacag gaagcataaa cttttcgatg gactccttcc caacgtgaat gaacaacagg
     7801 ataatctttt ggatcgtcag agaatttcag aaccgctcct gcgcttaaat gaagttcgac
     7861 attgcttttt aaaaataaag ctcctgttag aaattcacct gctggaacaa ctacggtccc
     7921 gcctccgtca cttgctgcag catcaatggc ttgttgtatt gcttcagtat tcaattcatc
     7981 aattgatgcg ccaaatgtca aaatatcata catatttata atgcctccac ttcaatcaat
     8041 gcttgcaaga atgcaccaac gcctttttga tcattacaaa taattggttc actgatgtag
     8101 taagcatatg aaccatctcg ctgatctgct ccgcctaacc ctgctacttg acagttttta
     8161 ttcaagttca gccagccttc ttttgtttcc agaacaaatt catcaagtaa tccttgatgt
     8221 gatttcttca cttgtggaag ccattcttct ttgttcagca gtcccaaacg tattccttta
     8281 gccattgcgt aaacaaacat actactgccg gaagcttcca gataatttcc tttccgtttt
     8341 gtttctgttg ttacttgata ccatgtcccg ctgttttctt cttgatatgg aagtaatgca
     8401 gccagtgtct tttctagaat ttctttcagc aaagaacaat ctgtttcttc atgaagtaat
     8461 tcataggtat ctgctgcagc catcaaatac cagccaatcg atcggctcca aaaatgatgg
     8521 gatagacctg tttttggatc agcccatggt tggaccttct tttcatccca tgcatgaatc
     8581 agcaaatttg tttttggatc gaatagatgt ttataactga tttcaaactg tctcaaaaca
     8641 tcttggtaat ctttttcttc actaaaattc tggataaatt cagcataaaa aggagaaccc
     8701 atatataagc catccaacca aatttgataa ggataaattt ctttatgcca aaaagctcct
     8761 tcggatgtgc gtggatggtt tgccaactgc tgggaaagga gttctgctgc ttttttatat
     8821 ttttcttcgc ctgtttcttt gtacaataaa aagaaaagct ttcctgtatt tacatggtcg
     8881 atattgtatt cttcaacgct gtagccacgg atcgttccat cttcttgcac gaaatagtcg
     8941 atattgtctt ttatgaaatc aaaataaatt ttttcttggg ttcgttccca aagtaattgg
     9001 aaccctttaa gtacgacgcc atagtcataa gaccattttc ctttatacca cttttcttca
     9061 tataagcgag gtgttctttc catgatactt tttgctaatt tctttgacca gttttccatt
     9121 atttgctctc ctttaaaaat taaaatagga tttgggacaa ataccaagaa gtatttgtcc
     9181 caatcgtcta tattactgtg ccgctgcttt gtatgcttcc tcgtactctt gtgtgattcg
     9241 atcgcctcct tgtgctttcc agtcttctac agcttttttg aatccatctt cgtcaagctg
     9301 tcccatgatg tattgcaccg tagcatcaat gacgattttt tcaatttctg atcctacttc
     9361 attgttcgtc ggtgaatcca atggcacaga aggatccatt acagcaaatt cttcattttc
     9421 tttgatcaat tgattagaga attctttttc agggtctgta tctttgaaag agaacgtcac
     9481 ttcactagga cgagagcttg ataacggttg cacctcttgt tgccaaagat ccatatcgat
     9541 aaattcgata gaaccatcat cattcaattc ataatgcgtt ccttcgatac cgccagtcat
     9601 caatttatac acatcttctt ctaaaagatc atcaacaaat tgaagtaatt tcttcaattg
     9661 tgcttcgtct tttacttgag atttgggaaa tgctagcaag ccgccaatac catttccttc
     9721 tgaccaaaca tgataaccgc cgccttcacc atctgagatc ttgtttacag gcactaattc
     9781 catatcatct tgaatacctt gacccatcgt cttcagattc ttgatatcca ccattccagt
     9841 gtagattcca gttcttcctt gtgcaaattg ttcttgctga tcagtctttt gggtaactgc
     9901 aaagtcttgt gccaaatagc cattctcaaa tagatctctt gaaaaattca aagctttcat
     9961 atactcttct gtatcaaatt ctggagtgaa tttgccatta tcgtctacag cccagccatt
    10021 tggtgctcca aaataagaag tgaaaagttt aaagctggta taacgaatat cactaggcgc
    10081 acgatcgcca aaaccaactg tgtcgtccac accatttcca tcaggatcgt tttctgtaaa
    10141 ttgtttagct acttcataaa gctcatccat ggtagttgga acatctagtc ctagattatc
    10201 caaccagtct tttcgaatga ctaagccagc acgagcgtag tctttttgta tcggtacgcc
    10261 gtacaaggca ccgtcgatac tcgcagcttc gattctatct tcagaaattt gacttaaatt
    10321 tttatagtct tttaaatatt ctgatacatc ccagaatacg cctgatttta acgcattgcg
    10381 gacagaagag tttttcaaca tcgcaatttg aagtgtaacg atatctccta gttcatcaga
    10441 agccaatgca gttgttaatc tttcttcttt tgaagcatca ggaatccagt tgaatgtcag
    10501 ttccgtatcg gttttttctt cgatcaagtt cacaatcgtg tctgtaggcg gtgaagcatg
    10561 atgcaaaata tttaaccaag tgattttagc ttttccatct tctgtctctg aagaactgtt
    10621 acttgaactg ctgccgcatg cggcaagtgc tagaattcct gcaaaactaa gacctaattt
    10681 tacgagcgtt gcttttttca taaattttct ccttcactgt tttaataata tttttgtttt
    10741 cttctgtttt ttctgtatat gagttcttcc attccaaatg gcaaaatata gaatttgctg
    10801 tccacgtgac tgcggaaaag aagagactgc caccgataaa ggttaaaaca cctggcattg
    10861 tttggatgat catcagataa atccctacca tacttaatat caacactaat gagtaatgaa
    10921 gatgtgagaa tccgaataaa aatgccattt tcattttgaa aaaatatcct ttccaatcat
    10981 aatgagccat gattgggaaa atatagagtg ctgagagcac atatatgaac gcagcaatat
    11041 acaaagcgat cctaagatac caattgtgta tgaaagaaag atccacaagt aaaacaatcc
    11101 cgatggcgcc atatatccag ctcatcagca aggtttcacg atagttttct ttaaaatatg
    11161 tgaagtacgt tttcgtcaaa ggaaacgttt cttttgagcg cagccatttt ctaatcactg
    11221 caaccatcgc atacgatgca ggaccgaaag taaaaactcc caaacctgcg atgactaaac
    11281 cgccccacag aaaattcaaa taaaccaact gtaaaatacg atttagcctt ccgtttattt
    11341 tatctaatga ctgcagcata tctttccctc tctttctatc ttagtaaacg ccgtcttctc
    11401 ctagcttttt ggcaatctta ttagctaaaa ttaccataaa caatcctacg acccctttaa
    11461 acaatcccat tgctgtactg aaacttaact gtccattctt caatccagct gtataaatat
    11521 aggtgtcgaa aatttctgca acgcttcgat tcaatgaatt caataacaag tacatatgct
    11581 cgaaccctaa gtctaatgtc tgaccgattt ttagaatcag caaggtaatg attactggac
    11641 gaattgccgg caatgtaaca tgccatgttt tgcgtaagcg tcctgctcca tccatttctg
    11701 cagcttcata caactgtgta tcgactgcag ttatcgctga aaggtagatg atcgtagacc
    11761 agcccaactc tttccagatc acttgtccga tatatactgt gcgtgtccat tcaggggatg
    11821 ttagaaaact gattttttca aatcccattg ttgcaaggaa ttcattcaat acccctccgt
    11881 caacattcaa aaatacataa gtaatcgaaa caatgattac ccaagacatg aagtgaggga
    11941 tgtaaatgat cgtttgaatc ccgtttttca atcgtttgtt cgttacttca tttaatagta
    12001 aagacaaaat gattggcatc ggaaaaaaca cgaagatatt taatccgaac aagatcaacg
    12061 tatttcttaa taatgtaaag aatgtcggtt ctgtaaacaa acgaatgaaa tgtttgaaac
    12121 cgacccaagg acttcccatt attcctaaaa atggttgata atcttgaaaa gcaataacga
    12181 gtccccccat aggaagatac ctaaaaatca agaaataaag gactcccggc agaatcatca
    12241 catataaaaa tttattcgtt ttgattcctg caattatttt ttttcgtctt ctgagctttt
    12301 cttctttttt cgatagcgtc agttgaaatg gttcttgttt ctttacactt tccataagcc
    12361 cctccttagt tttgtgaatg tttgctgctt atgacttcat gatagataac tatctgaatt
    12421 acgtatataa tcatttttat cgtaagtaaa aacgcttaca tagcaatgat ttttgtgcta
    12481 tacaaaacga taaagtgtat tttttcacaa ataaactacg catagcaaac cttctatttt
    12541 tttctatctg acacttagca taggaaatga ttatatacgt aatctttcac cgatgataaa
    12601 ttgaacatat agaaacagaa acatttaatt tattttgagg aggagcctat ctatatgaaa
    12661 aagaaagtct ctataggaga aagaagtttt acacttttca acaatacgtt tctaattttg
    12721 ctagctttga tctgtatcgt tcctttttta aatatcatcg ctacatcttt tgcttctaca
    12781 caagaagtcg tcgcgaaaaa gtttatcctt tttcctacta ccttttcttt agacgcgtat
    12841 cgctacattc tttctacgcc gaccattttt agagcacttg ctgtttcgat tggtgttaca
    12901 ggtgtcggaa cgatcgtcag tatgtgtgca acttcactga tggcctacgg tctttccaga
    12961 aagtatttgt ttggtcgagg tttcgtcaac tttcttgttg tattttctat gttgttcagc
    13021 ggggggatga ttccaacgtt cttagttgtt cgttctctag ggctggtcaa ttcttactgg
    13081 gccatgatcc tgcctgtggc tgttaatgca atgaatatga tcattatgag aaactttttc
    13141 caagccttgc cggatagttt ggaagaatca gcaaaaatgg atggttgcac agattttggt
    13201 gtatttttca aaattatgct gccattagct ttaccgtcta ttgctactat ctcgcttttt
    13261 tatgctgtta cttactggaa cacttatatg actgctattt tgtatatcaa cgattcatct
    13321 aaatggccga tacagattct tttacgccaa atcgtcattg tatcaagtgg gatgcaagca
    13381 gaaagtagtg ccgttgatgt gattccacca gcacaaacag ttaaaatggc tgttatcgtt
    13441 attgcaacag tgcctatgct gattgtttat ccttttgttc agaaatattt tgtcaaagga
    13501 gcactcgtag gttctgtcaa agggtgatta tgtactgaac gcaaaatggt agttgtgtca
    13561 gaagtggtca gcttcaagaa ataagaaggc atttacgaaa attgcttctt aaatttttgt
    13621 gaaatttcgg cttatttttc gaagaatcta ctcctggaac accgtgtatc agaggttgtg
    13681 aaagagacgt tcagccttga gcgatgataa aaactctcac aaacattgcg acgagtaacc
    13741 cacaggagca ataagaagcg attttgaaaa atagcttccc atatttcaca aaattatgcc
    13801 ttattgtcga tagcctgtct cttgaacgcc atttattcgt aaaaaagaac tgtgacaaga
    13861 cttttgtcac agttcttttt gcgtgcttag ccttgaaatt taactatcca taaatacaaa
    13921 tactagggtt attctaactt cttttattgc ttgaatcagt ccacaagaaa aacagcctct
    13981 tgattaaacg gcgtttatct tgttgattct gcggcaataa aatcagccag cagcaaaaca
    14041 tgaagtgctg ttttttgctg tcctctttta ttgcttgaat cagatcacaa gaaaaacagc
    14101 ctcttgattc acaaatattt ttttcgatat tctcccggcg taatcgattc cttcttttta
    14161 aagaaacgaa taaaattttg cggatttcga tattgcaatc tttctgcaat ctcttttacg
    14221 gagaggttag tctctttcaa ccattttttt gctacctcta aacgatgatt ttgaacaaaa
    14281 tcaccaaatt tttctcctgt ttccttttta aatacattac ttaaatagtt agggttataa
    14341 tgcaacctat cagcgatcac atctaaagac agatcacgat catattctgt gtagacgata
    14401 tgcataatat tctccgacaa atttttaaat tcatgatcag tgattgcttg agagcattct
    14461 gtgattggca gaactaattg ttctaaaaca agtttttcta gttctttggg atgataattg
    14521 ttcagtgctt ttacataaat ttgtttcatg ttatcaaagt tttttgaatc tactcccaat
    14581 aactgtccta attgaacgag ttcattgatc aagcggaccg aaactacttc ccgactcaaa
    14641 ggatttttat tttgtgcaaa caatgcatca atcaattcat gtactaaatt cttcacttcc
    14701 tgatttccag aacgaatggc ttcaaacaat cgattttgtt cttctatcgg atatctaata
    14761 agtgtttttt catgagcagc aggaacgatt tcctgataaa aaataattga acttggacca
    14821 gtatttacac gataatacag ggcttctttt gcccgatcaa ccgattgctt gctttcattc
    14881 agcgtttcga accggttact gatgcctata ctgatagtta aattcaagta ttcttttaca
    14941 cgtttttgaa tgagtcggca atactccatg acttttttgc ttgcttctgc atcatcttta
    15001 tccattcgat aaatagtggc ttgcatttct tcattcaaaa cgatcggcag cattcgattt
    15061 tcctttggca caatttccgt gatcatgttg ttgatcgcta aaagtagcaa atcacgctcc
    15121 ccaccgtgac tatcttctaa cagatcgatt tgaaccaaag ctgtataata gcagtcattt
    15181 tgagaactat aaccaaattg ctgcaaccgc tgatctagtt ctcgcctttc tactcgattt
    15241 ctaaataaac taagtacaaa tagcgtttcc agctgtggct tttgggtaac taagtgtgca
    15301 cttaacgctt ctttttctcc tatgatccga ctgactgatt gagcgaccaa atctagttct
    15361 ttcccactga atccttttga tttaagattc agacgttcct gtatttgaga aatcggacgg
    15421 gcaaatctgt ccgaaaataa gtaggaaaaa agaccaatga gtcctaccag tgttaaagac
    15481 actgcaacta gcccgattct cagattgcgg atcattgcgc caattgcact agagtcaact
    15541 tctaatctgt aaatccaatt attataatct gatttcagta ctatatacgt tttatctttt
    15601 tctcttatca ctttcagctg attgtaatct agatccacgt ccgttaatac agttggttgc
    15661 tctttatttt ttactgtctg agtagtaaaa aggttgccaa cttcgttttc aatagaaagt
    15721 atgtcttctc cactttcacc aacaacttgt tctattgtat gtttctctat cgtagcaatt
    15781 cccaatgcat atttttcttt ttcaaacatt ggcaaagaaa tcaccatttc gattcctttg
    15841 tttttctttt gccaaaataa attatttttg ttatttatgt acttctgttg atacttttca
    15901 acttcctctt cggtcagttg actcaacgat ccattgatta ctccccattt accagccaaa
    15961 ctgactaaat cataattatt atcatccata acaatcgttt ctataaaatt tagttctttc
    16021 ctgatttcag aataagtgga gtaatctgta tatgtcagcg gatgcttgaa tatgtccgag
    16081 aaatttttgg tcgaaccata cgtagaaaac gaatattcaa tcgttctaat tttccattca
    16141 acgttagttt taacttgcct gagcaaattc tttttgtctg ttaaataact cgattcgatc
    16201 gattcatagg tattctggta aatgaataaa ctaaatccta tgacaagtac ggctcctaat
    16261 aaaaacatcg gtaaaaatat tttataaaat actgtacttt tcttcatttt cttcctctcc
    16321 tccttttaaa ataaaaggct ttcatttttc tgtaaaattg atactcatct aattaaatga
    16381 gcattccccg ctttcaagaa tagcataatt aaaaataaaa atccaagtaa tttttaacgt
    16441 gtgcaatctt ttcatatcaa agatctattg acttatcgta gttatcgtaa tatgatgaat
    16501 gcgttaacaa aaagtgaaaa agtaaggaaa atgatggaat ggtaacgatc aaagatatcg
    16561 ctaaagcagc tggcgtttct catacgacag tttctcgtgc tttgaataac agcagtttaa
    16621 taaaaaatga aacaaaacaa aaaatacgac aactagctaa ggaaatgaat tattcgccaa
    16681 actatagtgc aaaaggttta gtgaatcaaa aaaaatatct aatcggacta tttttctcaa
    16741 gtttgcataa aggaacttca tcaaatttcc tagcagattc cattgcaggc atccattcag
    16801 tattagacac aaattacagt ttatctgttg aaagtatcga tgttgttgat ttaacagaaa
    16861 tcaacctgca acgctacgat ggactgatcg ttatgagtca aagtgatgat gatcagcctt
    16921 tcatcgacta tctcaaagaa aaagaatttc ctttcgttgt tgtcaatcgt cacatcaatg
    16981 atccagcggt tatcaacgtc actgccgatg atgcggccgg tgttatgcag gcagtagatt
    17041 acggtattgg atgcggacat acgaagatcg cttatattgg cggaaagaaa aattttcgtt
    17101 cgacaaaaga acgggaaaaa ggggtattga aaagtctaaa aaaagcgagc atccctgtca
    17161 atctagccta ttttttaaca ggagattaca gcttagaaag cggcctccaa aacatggaat
    17221 acctattatc actttctgac ctgcctactc tggttttttg cggcaacgac gacatagcga
    17281 ttggtgcatt gagagctgta catttagctg gcctccgtgt tccccagaac atttctctga
    17341 tcgggttcga tgattctcca gtcgtctcct atctcaatcc gccgcttacc accgtacgta
    17401 agcctttgaa agaaatgtgt caagaaggaa caaagctttt actagatttg atcgaaggca
    17461 ggacgatcga acaatctaaa attgagctct ccaccttgtt gatccttcgt gagtcgatca
    17521 attacttgta aactacaagt aattttatat aaaaatgtta acgtgtgcat aacacagaaa
    17581 ggaagtttat atgaaaaaac tgacaaaaga attagtgaaa aaaaacgaag cacctgtaaa
    17641 agttcttcag tttggtgaag gcaattttat gcgtggattt attgattggc agattcagca
    17701 gctgaataac caacaattgt ttaaaggtaa tgttgcaatc attcaacctt tagaacaagg
    17761 tcttggaaat atgatgaacc agcaagataa tttatatacg gtcattttac aaggactcag
    17821 caatggcgaa atcgttgata cttccgagat tatcaccgta gtagaacaaa tgatcaatcc
    17881 ttatgatgaa tgggatgctt atctatctct agcagaaaat gacgacttgg cctatatcgt
    17941 ctccaataca acagaggcag gaatccaatt cgtggagact gataatttaa cagatactcc
    18001 cccacagagc ttcccgggca aactgacagc ctttttatac cgacgtttca aattaaacaa
    18061 agctggcttt accatcattc cttgcgaact gattgacaga aacggcgaac gtctaaaaga
    18121 aatcatttta cgctacgcag aaaaatggga tttagaacct gcttttgttg agtggttaga
    18181 aaaagaaaat gttttctgtt gtagtttagt tgatcgcatc gtcccaggtt atcctcgcga
    18241 agatgcaggt gttttcaatc aacggcataa ctatgaagat caattgatgg tcaaagcaga
    18301 accattcatg ctttgggtga tcgaagggcc taaagaattg gagaatcaac taccattcaa
    18361 acaggctggc ttgaatgtca tcatcacaga tgatatgact ccttatcgtg aacgtaaggt
    18421 gcacttgctt aatggaccgc atacagcgat ggtccctctt gctttgttgg cggaattgga
    18481 aactgtagaa gaagtaatga aagatccttt attctccgca tatgttgatc agttattcaa
    18541 tctagaattg attcctatgc tttctttacc taaagatgaa ttagccattt atgctgacca
    18601 aatcaaagaa cgtttcttga atccttttgc ccatcacaaa ttagaagcga tttcattaaa
    18661 tagtgtttca aagttcagca cccgtctgct tccagtgttc aagaagtata tcgaagaaca
    18721 aaatcaggta ccaccgttaa tcactgtttc actagctgcg ctacttctta tgtatcgagg
    18781 cgatcaagta aagccacatg atgatgaaaa gacgataagc gaatttactg atgcttggtc
    18841 tgataatgga acagctattc ctcgattatt gcaaaacgct gcgctttggg gagaagattt
    18901 gtctcaaata ccgaatgtga cagatacagt tcaagaaata gctgcaaaga tcgatcaaaa
    18961 aggtgtccgg tcagtattac aagaaatgaa aggaacgatg gtccatgctt gaaaccctgc
    19021 aaccaacaat gaaattaaat cgacgagaca gtgtggtcgt cgcattaacc cctattccaa
    19081 aacaaacaca actgacgatt gatcagcaaa cgatcaccac tcttgaagat atcccgcaag
    19141 gtcataagat tgcattgggt gatttgaaag ctggagacaa cgtgatcaaa tatggctatc
    19201 caatcggtca tgtgacgaca gacgtaactg ccggtcaatg gctgcacact cataatgtaa
    19261 aaaccaatct ttctggtgaa ttggattatc gatatgaaaa agatgtccat ccaagtcatt
    19321 acctttttga gaaccgaaca tttcaaggtt acttgcgaaa aaatggaaaa gtagggattc
    19381 gtaatgattt gtttttagta cctaccgttg ggtgtgtgaa tggcattgct gaactgatcg
    19441 tcaaacagtt caaggaaaaa catccagatc tgggacagtt tgaccatatt acgattttaa
    19501 agcatcctta tggctgttcg cagcttggaa aagatcatca aaatactcga gaaattttag
    19561 cggacgcagt aaatcatccc aatgccggag gagttttagt atttggatta ggttgtgaga
    19621 acaatacagt tcctgaattc aaaaaaattt taggtgaata tgatgaagaa cgagtgaaat
    19681 ttctagtggc tcaagatgtt tacgatgaga tcgaacaagg tgtggctcta ttagaagagc
    19741 ttttaacagc ggcggaaaat gaccagcgca tatcagtccc gctctctaag ttgaatgtcg
    19801 gtttgaaatg cggcggttct gatggtctat cgggaataac tgctaatcct ttacttggtg
    19861 cattttctga ctacttgatt gctcaaggag gcagcacgat cttaacagaa gtgccagaaa
    19921 tgtttggcgc agaacaagta ttgatggcac gagcggaaaa tgaagaagtt tttgactcaa
    19981 tcgttgactt gatcaatgac ttcaaacagt atttcttgtc ttacggggaa ccagtttacg
    20041 aaaacccatc tcctggtaat aaagcaggtg ggatcactac attagaagat aagtctttag
    20101 gctgcacgca aaaatcagga agctctcctg tcgttgatgt gctacaatat ggcgaaaaaa
    20161 tcagaaaacc agggcttagt ttattgcaag ctcccgggaa tgatcttgta gctgcctctg
    20221 ctcttgcttc atccgattgc cagttggtct tgtttaccac aggaagaggg actccgtttg
    20281 gctcatatgt cccaacggtc aaggtatcta cgaatacaac tctttttgaa cgcaaaggtc
    20341 attggatgga ttttaatgca ggcgtcttat tagaacaacc aatggaagta atcttagaat
    20401 cgtttgttca aaaaatcatc gctgtagcta gtggagaaga aacgaaaaat gaacaaaatg
    20461 acgttcgaga aattgccatt tttaaaaacg gagtaacact ttgattttca taaaacagta
    20521 taaaaagaaa gaaggaagat ttatgttttt atctgatgat tttttattaa aagacgattg
    20581 ggcgaaaaag ctttaccatt cctacgcaaa aaacatgccc attattgatt atcactgtca
    20641 cttagatcca aaagaaattt acgaaaacaa caatttcagc aatctgacag aagcttggtt
    20701 aggaggcgat cattacaaat ggcgcttgat gcgagcttgc ggcgtgcctg aagaaaaaat
    20761 cacaggaaat gcttctgatt ttgaaaaatt tttagcttgg tgtcaaaccg taccaaaaat
    20821 tatcggaaat ccgctttaca gttggtcaca tcttgaattg aagcgtttct tcggtattga
    20881 cttgttgata aatgaagaaa atgcagagaa aatttggaca caagcaaatg aaattttggc
    20941 agctcctgat tttcgccgtc gggaaatcgc aaaaaaatcg aatgtagaag tgatttgtac
    21001 aacagatgat cccgcagacg acttgcacta tcatcagttg cttgctcatg aagaaccaga
    21061 tttgaaggtt ctaccttcat tccgtccaga taaagcactc aatattgaaa aagaaggatt
    21121 taatgcatgg gtcacactac tggaagaagc agctgaccaa acgatcacca cctatcaaga
    21181 actgatagaa gtcttagggc agcggataga atacttccat caacatggat gtcgtgtttc
    21241 cgaccacgct ttagacatct tacgctataa agaagcggat gaaacagtat tagaagagat
    21301 ttttcaaaaa gcacgagcta acaaactatt atcttcagat gaaatcgatg cttatcttac
    21361 agaaacactg atacatttga cccacttcta tcattctcat aattggacga tgcagctgca
    21421 catccatgct tatcgtaact gtaatacaca aatgttggaa aaattagggc ccgataccgg
    21481 ctatgatgga atgaatgatc tttctttgac tattcctctg caaaaattat tgaaccgtgc
    21541 agaagaaacg gatcagttgc caaagacgat cctttattca ttgaatccga atgactatcc
    21601 tgcgatttta gctttgatgg gctgtttcca aaaagaacag aatggaaaac tgcagttagg
    21661 ttctggatgg tggtacaacg atactcgagc tggtatgcgc gatcaattga cacaatttgc
    21721 tgatggtagt gctttgggga attttgtcgg catgctgaca gattcaagaa gtttcctgtc
    21781 ctacactaga catgaatatt tccgtcgtgt tctttgtgaa tttttaggcg aaatggtcat
    21841 gcgaggagaa gcacctgaag atgaacaact tttaggaagt ctagttcaag cgattagtta
    21901 tacaaatgct aaaaattact ttggcttttt tgcctaattg attaatagta acagtaacga
    21961 atcaaaaaca ggatagtgaa ataacggaat ccgtttatcc acgttttaga gaagaagacg
    22021 gaccaa
//
LOCUS       DAFTHM010000040        21441 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFTHM010000040 DAFTHM010000000
VERSION     DAFTHM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.040"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            122..823
                     /locus_tag="L7C88_001460"
     CDS             122..823
                     /locus_tag="L7C88_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBP9558297.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1432..2448)
                     /gene="tsaD"
                     /locus_tag="L7C88_001461"
     CDS             complement(1432..2448)
                     /gene="tsaD"
                     /locus_tag="L7C88_001461"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBP9558298.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2445..2909)
                     /gene="rimI"
                     /locus_tag="L7C88_001462"
     CDS             complement(2445..2909)
                     /gene="rimI"
                     /locus_tag="L7C88_001462"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBP9558299.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2916..3458)
                     /gene="rimI"
                     /locus_tag="L7C88_001463"
     CDS             complement(2916..3458)
                     /gene="rimI"
                     /locus_tag="L7C88_001463"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBP9558300.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3442..4164)
                     /gene="tsaB"
                     /locus_tag="L7C88_001464"
     CDS             complement(3442..4164)
                     /gene="tsaB"
                     /locus_tag="L7C88_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBP9558301.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4355..5335)
                     /locus_tag="L7C88_001465"
     CDS             complement(4355..5335)
                     /locus_tag="L7C88_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9558302.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5359..6843)
                     /gene="galT"
                     /locus_tag="L7C88_001466"
     CDS             complement(5359..6843)
                     /gene="galT"
                     /locus_tag="L7C88_001466"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBP9558303.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6855..7844)
                     /gene="galE"
                     /locus_tag="L7C88_001467"
     CDS             complement(6855..7844)
                     /gene="galE"
                     /locus_tag="L7C88_001467"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBP9558304.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            8092..8259
                     /locus_tag="L7C88_001468"
     CDS             8092..8259
                     /locus_tag="L7C88_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBP9558305.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8321..10132)
                     /locus_tag="L7C88_001469"
     CDS             complement(8321..10132)
                     /locus_tag="L7C88_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBP9558306.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10129..10494)
                     /locus_tag="L7C88_001470"
     CDS             complement(10129..10494)
                     /locus_tag="L7C88_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBP9558307.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(10657..11052)
                     /locus_tag="L7C88_001471"
     CDS             complement(10657..11052)
                     /locus_tag="L7C88_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBP9558308.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(11070..12032)
                     /locus_tag="L7C88_001472"
     CDS             complement(11070..12032)
                     /locus_tag="L7C88_001472"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBP9558309.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(12032..12244)
                     /locus_tag="L7C88_001473"
     CDS             complement(12032..12244)
                     /locus_tag="L7C88_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBP9558310.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(12265..12963)
                     /locus_tag="L7C88_001474"
     CDS             complement(12265..12963)
                     /locus_tag="L7C88_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBP9558311.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(12983..13525)
                     /locus_tag="L7C88_001475"
     CDS             complement(12983..13525)
                     /locus_tag="L7C88_001475"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBP9558312.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(13657..14661)
                     /locus_tag="L7C88_001476"
     CDS             complement(13657..14661)
                     /locus_tag="L7C88_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBP9558313.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(14658..15647)
                     /locus_tag="L7C88_001477"
     CDS             complement(14658..15647)
                     /locus_tag="L7C88_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBP9558314.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(15644..16450)
                     /locus_tag="L7C88_001478"
     CDS             complement(15644..16450)
                     /locus_tag="L7C88_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558315.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            16616..17572
                     /locus_tag="L7C88_001479"
     CDS             16616..17572
                     /locus_tag="L7C88_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBP9558316.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(17649..18167)
                     /locus_tag="L7C88_001480"
     CDS             complement(17649..18167)
                     /locus_tag="L7C88_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBP9558317.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18255..18404)
                     /gene="rpmG"
                     /locus_tag="L7C88_001481"
     CDS             complement(18255..18404)
                     /gene="rpmG"
                     /locus_tag="L7C88_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBP9558318.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18632..19078
                     /locus_tag="L7C88_001482"
     CDS             18632..19078
                     /locus_tag="L7C88_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBP9558319.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(19273..21168)
                     /gene="asnB"
                     /locus_tag="L7C88_001483"
     CDS             complement(19273..21168)
                     /gene="asnB"
                     /locus_tag="L7C88_001483"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBP9558320.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         6452 a         4550 c         3699 g         6740 t
ORIGIN      
        1 aataacaaat tatatttgta aagtattaaa acttgtttct aatgttggta tgttaaaact
       61 ttacaaattc tttaaaaaaa gtgacaataa atatagtgaa caataaggag aggacttttt
      121 aatgcgtgtt aataaaatcg attttcactt ttcaaaactc agatatcaac ctgattttga
      181 acatttctcg gatgaagagt tccaacagat caaggaacat actgttcttc gttcttataa
      241 aaaaggacag atccttttcg acgatggtga tcccagacaa cggttgtata tcttgaccaa
      301 aggactcgtt cgtttagaac gttatgatga aagtgcaact tattactact atgactatgt
      361 gaatacaaat aacctttttc ctatgtcagg aatgtttgga gaagagacct acacttatac
      421 agctcaagcg atgactgata ttgaaacatt ctaccttcct gtttcctact atgaaaaatt
      481 agcacgaaaa aatcccgaac agttgatcta tatgatacaa aaaatttcta aagtagttga
      541 aatacatgaa ttgcgtatcc aaatcggatt gacctctagc gcctttgacc gggtaaaaca
      601 aaatttattc attttgaaag aagaattggg cgtaccaaca aaagatggtc atatcaccat
      661 tccttatccg atcaccttaa aagaattagc agtgaatagc ggcacgacac gtgaaactgc
      721 tggacaagta atcaaacaac tacgtgattc cgggctgtta gattatgaca aaaagcgttt
      781 tactttctgt aagacagcta ctactccagc tatgagagaa taacgcgaac aaaaataagc
      841 agtgaccctg ataaatatca gggtcactgc ttattttcct ccctaaaact tctgaaagat
      901 ccggcagttt tagatcactg gacaagactc aaagattttc tatgtgtgtt tcagttatgt
      961 aatattcact gtttgcaaaa aatactgtta gattaactag atgaagcgtc ttgtcctcat
     1021 ccgatctaga ttattcgata ttcctcgaca ataaacgatt actcagtgag ggcaatcaga
     1081 ggaacggata atgataaata agctgtaaaa aatagcaaaa taacaataat gattaaaagt
     1141 atgtaaaaaa tagggctttg acaaaaacgt gtcacagccc tatttcgatt aaacggtgtg
     1201 tacctgtcaa ctcttcggtc acaagtcata atgttcataa acatgaggag ctgttttttg
     1261 aaattgttcc ttgtgaatca gagttaaacg acaggcttac gaactcttga ttaaacggcg
     1321 ttcaaaagct tgcatacgcg gtaataagaa cagccaggtc aaaaacatga gaagccgttt
     1381 ttcctgggct gttcttatta cttgatgcag ggcagctttt tcacaacctc tttattcaga
     1441 taaaaccaag cttggatcag cattcaactg atagctagca aaatttcttt tttgcatttc
     1501 cacatgtgct gctgctccaa tcattgcagc attatctcca caaagtcgaa gagggggaat
     1561 cactagttct acctcaggga gtttagctgc caaagcatcc tgcaatcctt cacgcaaccc
     1621 ttgattggcc gctacacctc cagctataat cagttgcttg actggataat tttgacaagc
     1681 tcgaagtgtt ttagtaatca atacatcgat cacacttgct tgaaagctag ctgctaaatc
     1741 atttttgtct agatcttctc cacgctgttg tgcattatgc accaaattga taaatgcact
     1801 ttttaatccg ctaaaactga aatcataatt atcttcatgg atcatcgctc gcggaaaatg
     1861 gtaattatct tttccctgat gagctagctg atcgatttct tttccgcttg ggtaagaaag
     1921 acctaatact cttccaactt tgtcataagc ttctcctgct gcgtcatctc ttgtctcccc
     1981 aatgatttca tatgatccat cttcttgcat atagactaat tctgtatgtc ctccgctaac
     2041 aagaagtgcc atcaatggaa actggaatgg tttaaccaga cgggctgcat agatatgccc
     2101 tgccatatgg tttacaggaa taagcggcaa ttggtgtgcc caagcaaaag ccttagctgc
     2161 agaaatacca atcagcaacg agccgacaag tcctggtcca taagtgacag cgactgccga
     2221 taaatcttct gccgacacac cagcttctac cagtgcatct tccaagcata aggtgatttg
     2281 ttctacgtga tggcggctag ctacttcagg tactacgcca ccaaaacgtt tatgactgtt
     2341 tatttgagaa gcaacgatgt tagataagat ctctgttcca tttctaacga ccgctacact
     2401 cgtttcatca caacttgatt caatcgccag aatcaattct tcattcattt catcgtctcc
     2461 gtttttaact ttctgctcat aatgatcgca tcttccgtcg gattgcgata atatgatttc
     2521 cgtttaccta atatacgaaa cttttctgat tcataaagtt ttcttgctgc ttcattagat
     2581 agacgtactt ctaaaaaaac atgcagcgaa tcttttattt gttccgtaat cagtaattgt
     2641 aacaaatgcc gtgcatgccc ttttccttgt tctgaaactg caacagcaat atttgtgatc
     2701 tcgacttcat ctattacttt cgagtatcca ataaagccac agatctggtt atcttcagct
     2761 aaaagcagat aatcagagtg aggctgttgg atgtctgcca aaaactgcat tttcgtccaa
     2821 ggtgaaccat gtggataagc attttcgcta atcatccata cgcattctgc caagtacgct
     2881 tcatcaaaat ctttttttct gcaaatcaac taatctcact cattttctaa aagttttatc
     2941 atatccaacg catcttcttt tgtttcagtg taatatcttt ttttgatcgt tgttgcttga
     3001 aaccccaatt tccgataaag tctttgtgca tcttgattac tcatacgcac ttctaatgac
     3061 atcgtctcac agcgattcat tatagcaaag ttctcgattt cgtcaataag cagcgaaccg
     3121 attcgtttac gctgatatgc cggtcgaacg gcaatattcg tgatatggca atctaaaccg
     3181 aacgctcttg aaccgataaa accaatcatt cttccattat caaagatacc tagatataga
     3241 tgaggaagcg gtgacttcaa ttctgatata aaggcacttt ttgtccatgg caattcgcca
     3301 ttatagactt ctcgttcgac atccagcagc tctttgatat cttctgtagt caattctctt
     3361 agtacgtaac gacgatcgat ttgttcgact gttttttctg tataaatcat tttatcttga
     3421 aaaaagcttc tggcatacgc tctaaatttt ttcaacataa ctttcgtctc caggtgtgtg
     3481 cgtctccaac catttttctt ctgcttctac tcgttttaaa tagcgaggaa gaaaagcttg
     3541 tttctctgca actggttcaa ctaaagcacc taattgagcc acagttacac cacttggaat
     3601 atcccatgct ggaactgtat taatcatcgc actaggcaat atttccttta tttcagagaa
     3661 gaatttgtga caatcactcc cgacgaaata aatagcttca ttcagctttt gtagttgtgt
     3721 gaacaaatca gaagcagaaa tatgtacatc ttcaagtaca gtttctaatc tattttcttt
     3781 ccagcggtat gccccagcgt atacattttt tcttcgagca tcaaacatgg gcacaataat
     3841 attatccaca ccgatgcaat tagccgcgat ggttttcaga ctagatactc ctactagctc
     3901 tttatctaat gtataagcaa tcgtttttgc tgtcgttaca cctatacgaa gccctgtata
     3961 agaaccggga ccatcagaaa ccgcgattcg gtcaatgtct tttggactta tttgaagatc
     4021 tgcaaacaat tggtcgattg caggcatcag tgttacactg tggttgcgtt tgatatttgt
     4081 ttgtatttgt ccaagaattt gttcgtcttc taccacaccg atcgccaaag tttggtttgc
     4141 agtatctatt cctaatgtaa tcatatattt gatcctttct gctatgacat tctcgccttc
     4201 cattgtagca tactttttta ttctgaggat gaaaatacca aaggcaaaac tagtacaata
     4261 atacatgatt atctgctggc gggcaaattt tgccccttcc tgaaacacaa aaaagctgcg
     4321 gtatcactcc attttcccac agcttttcca tcttttattt cgttgattct cgaataatca
     4381 actctgtttc cacaataatc tttcttgaaa ccggtgcttt ggaattactt aattgaagaa
     4441 tcgtctccac tgctagctct cccatccatt cggtataaac ttttacagta gaaagcgagg
     4501 gcgttacata tttcgctaca ctgacatcat tgaagcccat cacagaaata tcttctggta
     4561 ccactaaacc tttttcttga atcgctttca gtgcgccaat cgctaatgca tcattagctg
     4621 caaaaagcgc atcaggaaca tgcggattcg tttttaaata ttgcttcact gcttgatatc
     4681 ctgactcgac agaaaaatct gcttcgataa ttggaccttc gtcgtagcct ttttctgcca
     4741 aaacttgttg aaatgccata attctgggat cttttagccg ctgatggttt ttcttcgtat
     4801 attctgttcc agcaagcata gcgatatgtt gcgctttatg ggagacaaag tgttcaatga
     4861 ctttttgaac acttgactta aagtcgacaa ctagagagtc gattccttga gaagtgccgt
     4921 cagaatctac caaaagcaag gcattttggg atcctttcat ttctaataac tgagcttcgt
     4981 cgaattttcc tagtgcgatc gttccatctg ccggaagatc actaatggaa tcccacgttt
     5041 ctttcaataa agtaacgttt gcttcttctg cctttttttc gattcctagg cgaatagata
     5101 aataataaag atcttcaagc tcttccgtat cgtcgtacca ctggatcagg cgaagcgttt
     5161 gcttagtatt tgctgcattt ttacgatgtt tcgtataatt taagcgttct gctgcttcaa
     5221 aaattttttg ctttgtggct aagccaacgg aaagatcagg atcatagttg agaactcttg
     5281 aaacagtagc aggagaaact cctgccaact gcgcaatgtc tttaattgtt gccatttgtc
     5341 tctcctcctt ttttacgttt ataaaatcgc agtaaatcgt tcaaacgctg cctgtccttt
     5401 ttcatctcgc ttgaatactc cagcgtcttc cagtacacgt gcaaaaacct gacctacaga
     5461 tttttgtacg acatcggtga ccgtatcttt cgtcaaatca ggatgttctt tttttaattg
     5521 ttctgcccac ggacgatgat attcagccat ctggttttct tctcctaata agaaatgctc
     5581 tacttctact agttctggtt tcaaacgagg tggtaaaaca gcaagcccca ttacttcgat
     5641 caacccaatg ttctcctttt tgatatgttg gacatcttta tgtggatgaa aaatcccatc
     5701 aggatgttct tctgaaacat tgttgtctcg aaggacaagg tccaactcaa agtaattgtc
     5761 ccttcttcgt gcaattggcg taatcgtatg gtgtggtgta ccatctgctg aaaaagctct
     5821 gatagatact gtttcatccg aatatgcttt ccatttttcc aatactgagt tagctgcttc
     5881 aataagcaag tttttctctg ttgattgcaa acggatcaca gacatcggcc atttcacgac
     5941 tcctgcgatg acttgcggat aatcttctag tttgataagt ttttctatcg gtgcttttgc
     6001 cataggaaat tcatgacgtc ctgcctgata atgatcatga gaaagaatcg atcctccaac
     6061 aattggtaag tcagcattcg aaccaacaaa gtaatgaggc aagacttcag taatccgaag
     6121 cagtctagca aatgtttcct ttgtgatttt catcgggcgg tgttgttctg ataaaatgat
     6181 cgaatgttca ttgtaataag cataagggga atattggaat ccccagcttt caccgtctag
     6241 attcattcga ataatccggt gattggtgcg ggctggatag ttcaagcgac ctctatatcc
     6301 ttcgttttcc atgcaaagca tgcaggtagg atagtctact tttaccgcct cgcgttctgc
     6361 tgcgatttgt tttggatctt tttctggctt agataaattg attgtgattt ccagttcacc
     6421 atactccgac tctgccggaa atttgatgtt ttttgcgatg gctcttgttt tgatgtagtc
     6481 atttttctta cttaaattaa agaaatactc agttgcttcc tctgggcttt tcgaatagtg
     6541 ctgtgcaaag aatgcattga cgactgaagg tggcggtgtg agaaaatcca ttaattgcgc
     6601 ttcaaaaatc tcttgttctg ctggcaattc tgaaagaaca ccattttctc ttgccttagc
     6661 gacaagctga tccaataagt ctacagattc ttccttaact ggtcttactt caatgctttc
     6721 tagagcatct tctcctacca tccctaaaag acgattctgt aaatataagc ggtccatttc
     6781 catccatccg ccagcttcga tcgcaagtgt ggcaaaatca caaatcgttt gactgattga
     6841 catatctcat tcccctattc ttcataacca tttggatggc tgacatgcca atcccatgct
     6901 gttttgataa tcgctttgat atctgtgtat tcaggtttcc agcccagaat ctctctcgct
     6961 ttttcacttg aagcgactaa tcggctagga tctccagctc ttcttggtgc tatttctgct
     7021 ggaatttctt ttcctgtcac ttctctagct gcttctagca tttccttgac tgagtatcct
     7081 ttgctgctgc ctaaattgaa gaagttgctt tcatttcctt ctttcaagta ttccaaagct
     7141 aaaatatgtg cagcaatcaa atcttctact tgaacataat ctctgataca tgttccatct
     7201 ggtgtatcat aatcgtctcc ataaacagcc aaggcttttc tttgaccaag agctacttgt
     7261 aaaatgattg ggacaagatg cgtttctggt gtatgatctt ctccgataga tgcatctgct
     7321 tttgctccgg ctacattgaa gtagcgcaaa gcgacatagc gcatgccata tgcttggtca
     7381 caccacttca tcattttttc catcatcaat ttactttcac catacggatt tttaggatta
     7441 gctggtgtat cttctgtgat tggagactct ttcggctctc cataagttgc tgcagtagaa
     7501 gagaatacga ttttattcac gttgaactcg tgcatgactt caagtaagat ttgcataccg
     7561 tatacgttgt tgttgaaata catcaatggt ttttcgacag attctcctac taaagagctt
     7621 gcagcaaaat ggattactcc ttcaatcggt tccttttcaa atacggaacg tagaaattct
     7681 ttatcccgga tgtctccttc ataaaaatga gcatctggat gtactgcttg tttgtgacct
     7741 gtgagcaaat tatctaccac agctacttga tacccctttt gaactagctg gtctacagcg
     7801 tgcgaaccga tataaccggc tccgcctagt actaaaattg tcataaaaaa cactcctttg
     7861 attagtaaaa ttgtgtttgt tgattctata taatttaaaa aacgaagttt acttttatgg
     7921 tgaaaacaaa caaagtaaaa tttcgtaaat tcatatggta aatttataat aaaacattta
     7981 gtaaacattt tcaagggttt tttgcaaagg tttacaaaca aacgtaaaac tagccttttt
     8041 ttctcttttg ttccataata gatataacaa ataataaatg aggtggattc aatgaaaaaa
     8101 tttgtatctg gaatattagt aggaagtctg gcaacagccg ctgccgttgc tggtttggtt
     8161 gcttctgtga aaaaaacagt gatcgatcca attgacgaaa aagaagcaat gatcgaagaa
     8221 aaccgtaaaa aagcaatgcg taaacgcgtt tctcgttaat aattatttaa aaatacgcat
     8281 gaagactttc taaaaaacag ataagtcatc atgcgtattt ttatttgtca gtcaatataa
     8341 gttgtgctat tttatctgcc tgtctcagat tccatggatc tgtataaggt ctagctactg
     8401 ctgcagttag ccaatccaca ccttcaacag gtattccata gcaataaaag tcagactgga
     8461 tttcccctga agcatcaatc acgcgattcg tacctcgctc aacatctata gcttctgaat
     8521 gataacttcc tgtattatct gaaaatgaaa aagggcgaac aagtttgttt tccttcaaat
     8581 tttttatgac aggattactt gaacgagaaa agcttgtttg tggcaatcga gcttcaatca
     8641 aatagcgact gctgatttct ttatcttgta gagaaataac atagcggttg tgcttttgct
     8701 gaatatcaaa tggcggttcg atcaaatgaa aaatacccgc atctatcagt gctgctaatt
     8761 ctttcgtccg aatgattggc ggaccgatcg ttaaaaagct atttagatga gtaaaccatc
     8821 cccatagtat ttctttgtat tccttagcag aaaaaacgtg ccattcaata gcctgccgga
     8881 ttggatcacg ccagtctttt aatgcatcaa atgttgaagc aaatgctcct gtgcaattgc
     8941 ctttttccgc ttcttttatc tgcccttcaa taaatattcg gctagcttct gaaaagggct
     9001 cattctgata ggcaagagga gtttctaaat acgaccaatc ccatctataa gggattagtg
     9061 ctggatgctt tccgagacac tcctctgaag agagggagag aaaatcatgc tcaaaatttt
     9121 tctttggaat cggcaagtga tattcttcga tgattttctt gtaataaaac aactcaacgt
     9181 cttttttcag atagtcaaaa aatgtttcgc cagtcaaaaa tcccgactga tgccattgct
     9241 ccaggttttc ttttgttagt aaccgtggcc atgccattgc tccgccttgc ttttgatttc
     9301 ttcctcgagg gtaataaggg agcccccttc ttgatccact gtatacaatc ggttccttgc
     9361 ctgatggatg atagaccagt tttccctttt cgttctcgaa gcgccctcct cttgatactg
     9421 taaacaatcc gacataatca aaaaaactta agcctagacc tcttaaaaag acattttctt
     9481 taggcggtat cttcgaaaga tctacatctg caggattaga aggaagctga tacagtaaaa
     9541 catttttctt tgcgtagtct acccacactc tttcttcttc tgtctcatca ttttcccagt
     9601 gaccgcttgc taaaacaagc tgatcgatag aatagctttg ctgatctgtc tgtaaaagat
     9661 aaccatcttt tcttttgctt acttttttta ctaaagaata aacaaactga atagaagctg
     9721 gaaattcttc ttgcaacttt gagaaaaacc agcgttgata gagtccgtat aaacatcgag
     9781 tagattgctg atctttttcc agacgattga tttcttctat aattagttgc ttatttttgg
     9841 ttaccgtctg ttcgatataa tctgtagcag gtcctttact ccattgaaac aagttgggtc
     9901 cctgtgttac caatcctcca ctggacaatg tttcatctgt aaaaagcgtc acttgttgag
     9961 aaacagaatt cattaataac tccggtggct gattcaaccg ccaaactcga cctccaggac
    10021 cattgggatc gaaaagaaaa agttcaagag aatgtctgtc ctgattatta tggagaatcc
    10081 tttctgctac acttaatcct ctaggtccgg caccaatgat ccctattttc atttgcatgc
    10141 ctccatttcg ataaattttt tcaataaaac agcatggttc tgatgttcat tttttgcacc
    10201 ataaacaaaa gtaatgactg gatgttcttt cataagttga ctgagtttaa aaatagcttg
    10261 cttcttttct tcttcgaaaa tcaattcttg ctggtatttc tttgcaaatg aagcaaatcg
    10321 ttctggtaca tggtcaaaag ttttgcgtgc ttcattacta ggtgcaattt ctttcaacca
    10381 cagatctaac tgcgcttttt cttttgaaat tcctcgtggc cagaatctat ccacgagtat
    10441 tctatagcca tcctcttttt cagcatcaag gtaaacacgt tttaatttga tcatagttgt
    10501 ttccttcttt ctaccttttc gcttagctta tatatgtaga taatagcaca aaataaaaaa
    10561 aatgaacggc acaactatcc attgcgccgt tcatgtgatc ttggtcaaaa tctaatgatt
    10621 gattcggttt ttaaagctgt catacaatca tctgttttat acttttttac ttttgatttt
    10681 tccagaccat ccgtcatatc cacccttaag taaataaatc tcttgataac ctgctttacg
    10741 taatttattt gctgtacgga tgctcaaact tttcttttga tcgtaaatat agacaggctg
    10801 gtcttttcga atagatccta atgaatcttt caaaacagtg taagggatgt ttcttgcacc
    10861 taaaatatgc ccagcatcaa acacatcttt ttcgcgaaca tcgattactt gtgcttttct
    10921 cattccttct cgaaattctt cttctgtcaa agtcgttgct gaacgtttgg ccattactcg
    10981 tagatagact tcccaaagga tgattgcaag cacaatcaat agcaaaatga tattaattac
    11041 ccataaaacc atgtaatgcc tccgtttttt taagcaaatt tcaaggctaa tgaggcagca
    11101 ccaatgacac cagcttcatt accaagctct gctaatttga tttttgttga ttctcttact
    11161 tgcgggaaag taaattcttt aaaatatttc tctacacggc tacgtaaaaa ttctcctgct
    11221 gccgatactc ctccacctaa cacgatactt gacggattta atgtattccc caagtttccg
    11281 caagctaaac ctaagtagaa gcatacgcga tcaacaacca tcaatgcaaa cggatcgtct
    11341 tcttgagcca tttcaaagat atctttactt gttacttctt ctccgttgtc tagcattgct
    11401 ttcagttttg aatcccctgc gtattcttct gccaagaaac gacctaggcg taccacacct
    11461 gtagcgctag atacagtttc taaacatccg cgtttaccgc aagtacattc gaacccttca
    11521 ggatccacag tgatatgtcc gatttctcct ccagctccgc tcacgccgtg aatcaaattt
    11581 ccgccagcaa cgatacctcc gccaacacct gttcctagag taacgaatac aacgtctgga
    11641 tcgttttctc cagcaccttt ccatcgttca cctaaagcag caacattcgc gtcattatcg
    11701 atagcgaatt tgattcctgt tcctgcctcg atcagttttt tcacaaattg aacttctgtc
    11761 cagtttaagt tatacgcacc aataaccgtt ccagcttcgc tgtccacgct tcctggggta
    11821 cccatgccga ttccgataaa gtcttcggct ttcatattat ataaattcaa acgatgattg
    11881 attgattcaa tgatttcagg aacgatatgc ttaccatcat ccaaaatatt ggtatcgatg
    11941 ctccattttt gctgaatctc tccttctggt gttaaaattg caaattttgc tgttgttcca
    12001 cctaaatcaa tcccaataat cttcttgtcc attacaaatt tcctttcttt cggctttctt
    12061 caattcggtg ctctcttttt aatatgcgcc acgctgtcat gtatgtatca tgatcaatca
    12121 aacggctatc atacagatta cgcaattcga tagtcattaa ttcaatgtca tagatgcgtg
    12181 cacccacata gataaagatg ccaaattttt tgaacagctg ctgtacatca tataagctct
    12241 ccatctttaa gcacttcctt catattatac aagtaaacca tattttttta aacccagtaa
    12301 aatacatatt acaaaaagaa atacaaaaac tagtgtagaa agaatccttt ggtgtatcga
    12361 atagcttgtc tgttgtttcg gtagacccaa aacattccct aacactaatc cgccaattag
    12421 cccaccgaca tgtccccaaa catctacaga ggtatccaga agaccaaaaa caaatgtcaa
    12481 cacaataaat aaaagaaaat gtctgactag ctgctggatc gctgggttat gtttaaaatg
    12541 aaaccctaag ataaacaacg caccgaacaa accgaatatc gaagtacttg caccaccaga
    12601 cagaacattc gcttcgttaa aagcaaagct tgctgtattt cccattatcc cgctgaacat
    12661 ataaatcaag aaaaaacgcc aatggccata gattgcctcg atttgctgcc ccataaaata
    12721 cagtatcagt gagttcatta cgaaatgcat cagtccaaaa tggatgaaga ttggtgtcac
    12781 taaacgccac cattcattga agtgaacaag ataaggacca tacattccgg cataataagg
    12841 gatctcaagt cgcggaaata attccatcat gaggaagacc gctgtctgta tccctaaaaa
    12901 agcataggtc cataacggtc gtcttaacca tgcacgcaat tttatttgct gttgataatt
    12961 catgaaaacc tcccatttca ttttagtcaa taaacaattg ttggatcttc tgatcaaagc
    13021 tctccggttg ccattgttca ttcaattgtt cacgaaaaac aaggctacat gtttttttat
    13081 gaaaattatt taaataccgg tcgtaataac caccgccaaa accgattcga taaccggctc
    13141 tattgtagat aatacctggt acaatgagga gatcgatcat ctccggcaaa tagagcttct
    13201 ctgattgtgg ctcaagaaca ccaaaactcg aacgtacaag aacggactgt tcatccattt
    13261 cataaaacgc catctgacgt ttcggcaaag ttttaggtac aactattttc ttttgttctt
    13321 tttctgctcg ttggataacc ggctgtgtat ccagttcaaa ttcattcgat aaagtcgtcc
    13381 ctatcacttt tgctgacttc cagtactcgc tggcgaatag ctgtttatag attcgctgtt
    13441 ctttttcctt tttcttgcca cttttggcca gatttttcag cttttcgatt cctttccggc
    13501 gtaatcttac tttcaattgg tccaaaaact cacccttcct tctctcataa aatggtatag
    13561 gaaaaaaaga aaaatagcaa tcgaactttc aaataaatgc ataaatagaa taaaaagaag
    13621 acctagaaat gattggcctt ccttttttaa tgaatttcaa ctgttcagcg cgtgtttttg
    13681 tctgataaaa agtgcataca gaaaatatgg cgcaccaaaa agggcaatca aaattcctgt
    13741 aggtacttcc ccacttggta gaatcactct agcaaccata tctgcactaa gcagaaaaat
    13801 ggaaccgaac aaaccgctca gaacaaaggt ccagttattt tctttacgta cgactagctt
    13861 cgcagcatga ggagctagta gtcctacaaa agataaacta cctgtcaccg ctacactacc
    13921 gcttgccaaa gcaacagcta acaacaaaag gattttttga cttttagcca cgttaaggcc
    13981 taatccttgc gcgcgttctt gaccaaatga tagcaataca atcctctgtg cataaagtcc
    14041 tcctagcgga attaagataa ccgcccatgg aagcaatgcc caaacataag gccagctcgc
    14101 accccagatt gatcccgcta accatgcatt cacaaatcca taattttcct tagataattg
    14161 gatcgtgcat agcaatgtta atgcagaaag gccggcatta acggcaatac cggacaataa
    14221 gattcgattc atacccaaaa agccatttcg atcataggcc gcaagataga cacagcaagc
    14281 agctaaaaca ccacctagaa aggctacaac tagcaataga aacggcagcg aatagtgcga
    14341 aaagaaacct aaataaagca tcactaaaaa tcctgctccg gcattaatgc ccaatatact
    14401 agaatctgcc aattcatttc ttgttactcc ttgcaagata taaccagaaa cgccaagaca
    14461 agctcctgct aataaactga tcagtaatcg aggaactcga aattctctaa caatcagcgc
    14521 caaagaagat gattctttcc ctatgaacgt ggcaaaaagc tgatccaggt aaataaaagg
    14581 cgtaccaatc attaaactac ctatagacag gatgacaagt acaaaaagca agaaatagaa
    14641 cgtccaatat atttttttca ccgttgttcc ctccttactt gtatcagtaa aaacggaacg
    14701 ccaatcaatg caatgactaa tccaaaaggt gtttcaaaag ggggattgat catcctcgct
    14761 gtaaaatccg ccaacataac caatccaccg ccaactaaaa aagagacagg tagaacataa
    14821 cgatagtccg ttccaaccat tccgcgaaca actggcggaa ccaacagccc aataaatgaa
    14881 acaggtccga ctaacgaaac ggcaatggct gctaacactg caactagaca gaaaacaatc
    14941 aaccgcgttc gtttaggatg acttccaaga gctaatgcat gtgtttcact caaatgaatc
    15001 aaagatattg cttttcctaa tgaaaaagaa accaaaacag caagtatata taaaggaaac
    15061 aatactgcta attgtttcca tgtgatattg gcagctccgc ctacaaacca aaaagcaaga
    15121 tcctgctgca gattaaagaa ttgggtaagt gcttggctga tagcagtaaa aaaagaacta
    15181 atagctacgc cagctaaaat cagctgtaaa ggattcatgc ccattttcga aaactgcaaa
    15241 aaaccaaata cgagcaaagt tacagcaaaa gaacctgcca atgacattag aaacacagaa
    15301 aaatcagaag ctttaggcca aaaagcaaaa ctaagggcca ttgccaacga agcacccgcg
    15361 ttgattccta gtaagcctga atctgctaaa ggatttcttg tcaccccttg catcaatgca
    15421 ccgctcaatg caaaacaact ccctacaaga aatgctcccg ccacacgagg caaacgaata
    15481 tttcgtatga tttggtgact ttgttttgat ctatcaaaat caaacaacgc ctgccaaaaa
    15541 tctgcttttt ccacagtcgc tgcgccattt gaaagagcaa caaaaaaaat aatcaaaaga
    15601 acaaaacaga ccaaaagcag gagtctattt ttcttcatag tcctcataat tgatcctcct
    15661 gctcttttgg caacaaatca taggttagaa aaactggttt atttgttctt ggaagcgtga
    15721 caatcgttgc atcaatctca aatatttttt tcatacactc ttttgtgatc acttcttcag
    15781 gtgtaccttc tgtgatcaac ttaccgtttt tcattgctaa taaataatct gaaaaacgtg
    15841 aagcatgatt aatgtcatga atcgacatca agatcgttgt ttgtttcatt tgattgattt
    15901 cagtcaataa ctgtaggatc tctaattggt gtgccggatc taaaaatgtt gtcggttcat
    15961 ccaagatcaa gatatctgtt tcctgagcaa gcgccatagc gatccagaca cgctgggttt
    16021 gtccaccaga cagcgttgcg atatcccgca tacgaaatcc agctagacct gtagcatcca
    16081 acgcccactc aattgcttca tgatcttgcg tgtccatgcc actgaacagt ttttgataag
    16141 ggtatcgtcc gtaagatact acttcttcta ctgtcatacc tgtagggtgt tcactagttt
    16201 gtgctaataa tgcaattttt tttgcaagtt cttttgaact gtatgtagag atatcagagt
    16261 tattgacaat gatctttcct gatttcacag gtagtatacg ggtaaaactt ttcaataaag
    16321 tagattttcc acttccattt ggcccaatca aactagtgat tttcccttca ggaatcgtaa
    16381 cagacatgtt ttcaatgatt tttttgtttt cgtagccggc tgcaatgtca gctgctctta
    16441 atctcgtcat ttcacccatc ctttcgctga aaatcattct caattatgac gctgtttcaa
    16501 catttcgtca agcgctactt tcatatctat agccaaatga agcggttgac agcgttcgaa
    16561 atatcaggaa taataaccaa tgagaaagat tctcaattat gttaggagga aagaaatgaa
    16621 attaaaaaca aaagtattca cattatctag catattgctg ctggctggag tactgagcgc
    16681 ttgctccccc tcttcagata aagaaacagc tacaactgcc aattcgacga cttcatccaa
    16741 tagtactcat acagtcacag atacacttgg acataaagta gagattccaa acgcgcccaa
    16801 acggatcatc ggcagttact tagaagacta tctgattgca ctaggggaaa aacctatcgc
    16861 ccagtggact gttggcagtg gttccattca agattatctg caagatgatt taaaggatgt
    16921 cccaacgatt tcttatgacc ttccttatga gaaagtgtta agctttgagc ctgatttgct
    16981 gttgatttct tcttccgcta ctgtcgaagg cgggaaatac gaacaatata gcaaaatcgc
    17041 gccaacttat gttgtaaaaa acggaacaga tgtcacatgg gaagaacaac taaaagatgt
    17101 cggcaaagct ttggcaaaag aaaaagaggc agaaaaaatc atttccgatt atcaaaaatc
    17161 catcaagaaa actcgagaag aactagcaga taaaatcgag aacaagacag ctgcagtgtt
    17221 gtgggtgacc aacaactcag cctttatggt cagcaaaaat cggtcaagtg gaagaatcgt
    17281 atacgacgat ctggaatttg gtgttcctga tctagtggaa gaggtctcca aaaaagccac
    17341 ttctgactgg tctgctgttt cctctgaaaa gctagctgaa ttagatgctg actacatcat
    17401 ccttgtgaac agtgacaaag atgctgccat gttcaatgaa ccaagctgga agaatctaaa
    17461 agcagtgaca gacaatcatg tactgcaatt cggacctgaa tctagttggc tatataacgg
    17521 acctattgcc agtcaggaaa tggtcaatga tatcaaagaa aaactaaatt gattttaact
    17581 aaaaaaagca tcttcacgat tagtcgtgag atgctttttt tcttattaac aaactagacg
    17641 catagatttt attcttcttt tgaagcaacc ctatttttta ctctttccca tttttgaaaa
    17701 cgatgggcat atagattttc ttgatccgtt atcccctcat actcctctat aagggcgaag
    17761 tctgaaaaat caatattccc aatatacgta tcgccttcaa acgtgctatc gatcaatgtt
    17821 cgccagatcc gaccagtgta aggaagaagt tcttgaaaaa tccgactacc acccgaaaca
    17881 tagatatctt ctgagatcgt ttgactatac gacaaaagtt catcgatcga atgcattact
    17941 tccgcatttt ctttcgtgcg aaaatttggt tgcgttgtca acacgatgat atggcgataa
    18001 ggaagtgaaa gatcccccat tccttcatag gtctttcttc ccatcactaa aattcgatcc
    18061 attgtatgtt cgcgaaagaa acgcatatca tttggcaatc gccatggtaa caaaccattt
    18121 ttgccgatca gaccattttt atcttgtgcc cacatggaaa taaacatatt atccgctcct
    18181 tatgatttta gatgttttga gataaaaaaa gtctcaattc tttgaccagc aaggaattga
    18241 gaactttaaa aacattattt tgtttcacgg tgcaaagtaa ctttgcgttc gcgtgggcaa
    18301 tatttttgtt tttccaaacg atcaggattg ttacgtttgt ttttgcttgt tagatagtta
    18361 cgttctttac aagaagtaca ctctaaagtg atgtttacgc gcatgttttt ccctcccatt
    18421 tttacaagaa tcctctaaga tgactctcag acttgattat cttaccatga ttttttctag
    18481 attgctagtg tttttcacga ttttgttaag taaaactact tgacgataaa tacaacggtt
    18541 ttacttctca aacaaaatct ttttcttttt gtataaatac ccttacactt gtttatatag
    18601 attatgtttt ttaataaagg gggatactaa tatgccatgg aacatgaagg actttcctgc
    18661 atcaatgaaa aacttagata aattgacaag aaaaaaagca atcgacatcg caaatgcatt
    18721 attagatgaa gggtaccctg ataaccgtgc gatcccaatt gccattgatc aagcaaaaaa
    18781 atggtatgaa gatgctagtg aatcagaaaa acgaactttc gaaaaagaaa aaaatccaag
    18841 caagacggat gaacacgata cgaatcctcg tgctggaaaa ctgcttgatt cagatgtgat
    18901 cgtagaatat gaggaagaac aatggatcgt gaaatctaaa ggggcaaaaa aggcaagcaa
    18961 ccattttgat acaaaaaaag aagcaatcga aaaaggaaag caagtagcac aaaacaaaga
    19021 atcaactttg ttcatttata aaaaagatgg gacaaaagaa aaagaaatcg attattgaac
    19081 atatgtaaag gggttgtgac gaaaatcgtg tcacaacccc cttatgttcg aaacaatggt
    19141 gttcctctgc caactccgaa ccataagtca taatatctat aaaacgggaa gagctgtttt
    19201 ttgaaattgt ttcttatcac tcagtgttaa acggtaggag aaaacctctt ttttattgat
    19261 atttgatttt catcaaacag tcacatagtc gattgcttct gcttgcggaa tcgtttcatc
    19321 tacaaagtag actttatacc atgtcaagaa actgaagatt gtccagattt ttctttgctc
    19381 ttctttacgt ccttcgtgat ggtcatctag caacttcatg attttttctt gatcaaaaaa
    19441 ttcttttgca aaatctgctt cgaataatgc tttgacttgt tcgtagccgt gttcttcttt
    19501 caaccaagct ttgattggca cagggaatcc taatttcaca cgattcgacc attcttccgg
    19561 aagatgtttg ttcgcagctt gtctgaaaat atcttttgtg ttgttttgat tcaataaaaa
    19621 cttacttggt atttgttgag ccaatttcat gacttcgata tccaataaag gtactcggac
    19681 ttccaaagaa cttgccatag aaagtttatc tgcctttaac aagatatctt ttggcatcca
    19741 ttgatgaaga tcgacatatt gcatcttatt gacttcatct ttgattcctt ctgttttctc
    19801 gtaatgaaca gtcatgattt catccacaga tggtgctgtt tgatattttg gtgttaacac
    19861 ttctgatgct tctgattctt cgaacactcg agcatgaccg ataaaatatt cttttgcagg
    19921 agcaagtgat tcatataaat ggatccgtcc atggaagttt ttcatttttc cgattttacg
    19981 tcctaaatta tagcgtgttc cttttggtaa ttttttcaat ccttgagcaa tcacacggat
    20041 gaattttgaa ttcgtatgga atccatacgt ttggtatccc gcaaacagtt catccgcccc
    20101 ttctccagat tggactaccc gcacactttg tgaagcaaga tttgctaaaa agtacaaagg
    20161 tacgcaagaa ggatttgaat caggttcatc taagtgatac tggatcaaag ggaatgcttt
    20221 gaacgacatg tctccgtcga tcactgctgc tgtattatct aagtccaata gttcggttag
    20281 ttttctggct tcaatcgctt cattataggt tttatcatca aacccgattg agaaagaatg
    20341 atctggtttc aatacagagg ttacataact ggaatcaacc ccgctggata agaaagaacc
    20401 aacttctaca tcactgaccg tatgtgcttc aatagaagct tgaacggttt cgtcgatttt
    20461 ttcgatccat tcttgtcggg aatgcgtttc ttttgtttca aaatctgcat cccaatattg
    20521 ctgaatgtct atttttccat ctttatacgt ataataatgg ccttcaggca aacgatagac
    20581 atctttgaag aatgtttcgc cgtttaatgg agaatattgg aaagtcatat aaggtttcaa
    20641 cgcttctttg ttcaattctt tgttaaaatc aggatgaggc agaaaacttt tgatttctga
    20701 accaaacata aatgttccgt tcatttctgc ataataatat ggtttgatcc caaagtggtc
    20761 tcttgcaccg aataactcat tcttttcatt atcccaaata gcaaaagcaa acattccgcg
    20821 gatcttttgc aataattctg ttccccattc ttcgtaacca tgcaaaagga cttctgtatc
    20881 tgcatgtgtt tgaaaaacgt ggccagctgc aatcaattct tctctcaaag gctggtaatt
    20941 atagatttcg ccattaaaaa taatgatctt tgtccgatct tcattgtaaa taggctgagt
    21001 accgccctct aagtcaataa tacttaatct tctgaatcct aaagcaacat gtttatcgat
    21061 atattctcct gaactattag gtccacggtg aacgattcga tccatcattg tattaataat
    21121 tgtttttttg ttgtccttgt cgttaacaaa acctacaata ccgcacattt aactttcaca
    21181 tcctaatata aaattactgt ttatttcatt catatgcatc ttatcataga ataaatagcg
    21241 gacgaatatt ttctctctta caatttcgtc acgtgaaaac aaaagatgaa agtttctgtt
    21301 tttacagaaa ataaagtccc aatatctaat ttaccatgtt ttcttttttg aggctacctt
    21361 attctcttcg tgttaaaaaa atattagtgg atgctatttc caaaaaaacc agcaaaaaaa
    21421 gacacgacct aaagatcgtg t
//
LOCUS       DAFTHM010000041        20682 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFTHM010000041 DAFTHM010000000
VERSION     DAFTHM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.041"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            40..300
                     /locus_tag="L7C88_001484"
     CDS             40..300
                     /locus_tag="L7C88_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558321.1"
                     /translation="MNHEKFIEKCKAIVRERIENEIADLSGAVPEFSIFIVWSCKTLQ
                     NSKALVSASLKGAPYFEITLNGDKGEIYVDTYLKKSNECIKV"
     gene            341..568
                     /locus_tag="L7C88_001485"
     CDS             341..568
                     /locus_tag="L7C88_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558322.1"
                     /translation="MRNYWYVSLTNEYPRTIGDCSVRVVRSVQIKGKYSIVEMLREAT
                     PNEVDKCKLIYCGHGYWKDEYIQYNIERYIK"
     gene            565..849
                     /locus_tag="L7C88_001486"
     CDS             565..849
                     /locus_tag="L7C88_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558323.1"
                     /translation="MNDNYDYIKLIEKIRAEKDMDELATLFMNIISLVGLKMDEVAAL
                     NYFIAEQTIRAEHNAKFLKDRLDLDVKGLGVEGIFKVQEALVNVYVEKMQ"
     gene            890..1462
                     /locus_tag="L7C88_001487"
     CDS             890..1462
                     /locus_tag="L7C88_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558324.1"
                     /translation="MKLKDYIREGYNIVTTPNLAYKIQEDYPDALVFTDRALDAIPIG
                     KLLVDRYYSNNPAVLSAKPLQNAYAIERFTCEFTGYETVVPMTGETGRKVIQQIKKRI
                     AELTLDDGSNTNLLEIKLRDTDSVPEVYYKGQRMDEMPIGLVDITYHWDTEEYECQVP
                     KGANDITIEYYDSHNNKYLDRKIIGHKRDM"
     gene            1463..1774
                     /locus_tag="L7C88_001488"
     CDS             1463..1774
                     /locus_tag="L7C88_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBP9558325.1"
                     /translation="MIDVSSKQARARFYGSTEWRKLRSQCLERDHYECQWCKAEGRLT
                     TQHDSILEVDHIKELEYHPDLALDINNLRTLCKDCHNKRHNRMKYRGQQKKRKWDDEW
                     W"
     gene            1765..2025
                     /locus_tag="L7C88_001489"
     CDS             1765..2025
                     /locus_tag="L7C88_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558326.1"
                     /translation="MVVRKTANRDDVKRAEAIAMVDKAIDKLVLFKSQLIEGTTTVED
                     ISINNRLIGNANEVTGTFNINVDIDYTLSPFAHIVESNEQDG"
     gene            2186..2545
                     /locus_tag="L7C88_001490"
     CDS             2186..2545
                     /locus_tag="L7C88_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558327.1"
                     /translation="MADLQERNRLVSAEERRLNKLFKDIDKDKKKVVSGLITQAARLK
                     ILLDEMWIDISEKGDYELFSQSENQKPYERERPVAKQYNSRDQAYQRVIKQLTDYLPE
                     EKREPTKNAALDGSDLL"
     gene            2542..4185
                     /locus_tag="L7C88_001491"
     CDS             2542..4185
                     /locus_tag="L7C88_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBP9558328.1"
                     /translation="MTTLKPFYFDEYVDLYEKGVIPFNKERIQLITYLKNEVLVRDDI
                     YFDEEMIQKFIKYTEKNFFPLAKYQKFITPFIFCYQKEDDEVFFDEILNSIARGGGKN
                     GFMSARDSFFISPLYGVRNYDVTITANSEKQGKVSFKEVYEMVQMRKLEKQFYLTKMA
                     IVNNVTNSIFSYRTNNPKTMDSARDGCLEFDEIHQFESSDLVDIQRSGLGKIKHPRTF
                     YNGTNGHVREGFYDKMLERAQKIFSGENKNDRLFPFICKLDNIDEMDNPKMWSKANPM
                     FEEDSAYSKRLFSTVMKEYKKLEDEPSGRREFVVKRMNFTEGDAESDITTHEKLMATK
                     QELPNLNGRSCVAGFDYASIRDFATVGLLFKIDDKFIWQQHSFARKKFLDTFKLKAPI
                     KDWEKKGLVTIVDEPSIDPRHLIDWLNEKRKIHQIEIVCADGFRMDLLKPLLEKESYN
                     FEFIRNIRGVQSKVAPIIEDGFANERFIFGDDPMMRWYTNNSFIKEDKLGNKTFLKKE
                     PVRRKTDGFHAFLAALYKREEITDMDYEEAFDMLDEIEF"
     gene            4245..5417
                     /locus_tag="L7C88_001492"
     CDS             4245..5417
                     /locus_tag="L7C88_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBP9558329.1"
                     /translation="MSLFDIFKQSIRNEEPSEWIPDFVYGEEVSARAYLKIMAKNTVL
                     DFVARTMSTLEVKFKNKDGTSDWDYILNVRPNSDMSAATFWQKFFYRLLDDNEVLVIF
                     TDDNQLLIADDFSRTEYAVYDDVFTNVMVKNFVFERSWNMSDVIYMEYNNEELERFTR
                     GLFEDYAALFGRILEVAMRNNQIRGSVSIDSTGTANDEKGKDGKTRSQRLQEYIDRIW
                     NSFKTNSVAIVPKVKGFEYEEYTNKQGVSNQSLDELNKMKSSLIDDVANAIGVPTALI
                     YGEKAELDSNIKAFRKLCIAPLVKKLQDELVVKIISRQEYKNGERIEVKKVLQKDLLE
                     YATQIDKITSGGAFYIDEVRDEVDYDELPNNEGKIRIRTKNYEETVKGGENDNAES"
     gene            5404..6108
                     /locus_tag="L7C88_001493"
     CDS             5404..6108
                     /locus_tag="L7C88_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBP9558330.1"
                     /translation="MPKAKKVPFQFTNEIQNGKHILTLSGNVQKKYWRDDDVINAKDI
                     RDSLDTVTDDIVIKLNSPGGDVFEGIEIYNYLKDHPSNITVEVTGLAASAATFIVAGA
                     NDVIMNVGTSLMIHEASTFAWGNKQDIQKTLNALETIDDSILAIYSDKTGQSVDKLRE
                     WMNEEKWFTADEAVKYGFANSVKREEPQNEPQNIAAMIQDAVAVAIANLKEPVTNKIE
                     QESKQKSLIARLRKGE"
     gene            6113..7273
                     /locus_tag="L7C88_001494"
     CDS             6113..7273
                     /locus_tag="L7C88_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBP9558331.1"
                     /translation="MLKITDKTADAKKAFNAISSKEDATPEQINAALEEYVTAIAEDA
                     GKQVRAEYEELKNVTDNRVLEARGIPTLTAEETKFYNEAVKSGGFDSDVVWPETILER
                     VFENLQNDHPILGLINFTPTVGRVKVIRARRKGVAVFGPLHKDLEGQLDAEFGATEFV
                     QLALTAFFLISNDTLDLGPRWIDRFINLSLSEAVRDVWAKKIITGSGKDEPIGLLKDL
                     DGAVTSGVYPDKASAGTLTFAKEKIVLELAGVMKKLSKYTYKVDGDDEGEVKYRSVAG
                     RVYLIVNPVDYWDIVARVTFANLNNVYGTTMPFIAVDHIIESVDVPESKCIAYVDKEY
                     EATQSRAEKVYVYKETFAMKRATLYAVDMLGNGYPTNNDAAQVYDLDFTAGE"
     gene            7349..7627
                     /locus_tag="L7C88_001495"
     CDS             7349..7627
                     /locus_tag="L7C88_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBP9558332.1"
                     /translation="MNTEEFIKEYKARFRIFHTSEDEDIGKQLESGFADIKSLIGSFD
                     PSTYEKGKELVYERTRYLRNESLEYFYDNFQTMIMDASIDLAGAGYAN"
     gene            7608..7979
                     /locus_tag="L7C88_001496"
     CDS             7608..7979
                     /locus_tag="L7C88_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBP9558333.1"
                     /translation="MLDMPIKSNYKKPKIVAGDLNTPVTFFEFQPNKGPEPGDEEKKE
                     LYFCTALVYNPSMKDRDILGTKEGVTIKIRDPHQSYIPTNKHKVRILDYRYGDKVWEI
                     IDVSPDLEENSIVKIVLELIT"
     gene            7995..8399
                     /locus_tag="L7C88_001497"
     CDS             7995..8399
                     /locus_tag="L7C88_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558334.1"
                     /translation="MSNVKFEGVQETIQALEKKYGEKKTKTLTKKAINVGAEKVEKQL
                     QTDMTVFKDKGYTIAEVVRKNATYRDYKAEAEIGWNGPHQRYRIIHLNEWGYTRKGKQ
                     IRPRGFGVITKSLKNSELLYFDAVGEEVKKSL"
     gene            8396..8806
                     /locus_tag="L7C88_001498"
     CDS             8396..8806
                     /locus_tag="L7C88_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558335.1"
                     /translation="MKDMLNIIYEALCLNEYIHSMTYNENTEQYRIKFYEQPETADKT
                     GPMITIRPVDTPNEAYHGSNKELSVEHMIQIDVESKYRATCKQIQYEIKKEMKKLGFG
                     QISGQGLDEYFTETNRFVDARRYEGNTKIYDTEY"
     gene            8867..9454
                     /locus_tag="L7C88_001499"
     CDS             8867..9454
                     /locus_tag="L7C88_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBP9558336.1"
                     /translation="MTLVGFKKMTIGVFDSTGKIPAANLYVIEGEQNKGATVSAEISG
                     LSKEPSKVYGSNIAYYVSQKGTGDVSATFGLLDLPKEVNDKILGYKTDTNKISFLGED
                     TEPPYCAILMESEDLNGDTAMLAMFKGKFRRESINLNTTTNEAFEPEAEEYVFSAIAN
                     DVEGDAKGQTVAKYVGDEEASITGLKEMVFPAAGE"
     gene            9527..9994
                     /locus_tag="L7C88_001500"
     CDS             9527..9994
                     /locus_tag="L7C88_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HBP9558337.1"
                     /translation="MPDTFKIYKKNGTEFTKVAEGESPLSITGIAANTQVAKGDYQAT
                     RVVGGQESVKVDIPAFTTLPISVTGVTLDKTTAEVEQGGTLKLTPTVTPANATDKTGS
                     WSSSNTAVATVTGGNVTVKTDAEVGGTTEVSFTTTDGGKVAKCTITVIEKAAG"
     gene            10040..10348
                     /locus_tag="L7C88_001501"
     CDS             10040..10348
                     /locus_tag="L7C88_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558338.1"
                     /translation="MAKVRIELKEESGKKVYENIDTTGKDYRKALETIKKLNEDGVMI
                     WNRLDIYLDFAVGIFRDSKLTAEQILDGLPSEKVMSTLDDILGEVMGIESNPDPDAKK
                     "
     gene            10543..17277
                     /locus_tag="L7C88_001502"
     CDS             10543..17277
                     /locus_tag="L7C88_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBP9558339.1"
                     /translation="MANGKPLGNMIIKLDLDSSAFSKGLAGAKNAVNHQMKAMKSQMQ
                     VMNSSGNSLGALQAKYNGLGGVLQANEKQVELLTKAYKDSFDSNGNATASTAKYANQL
                     NQATARSASYESQMKTTVGQIARMKVETEGFTGKLKANSDVLINSGKKIEAFGKGVSG
                     IGSALTVGVTAPIVAGATAVTSAAISWESAFAGVKKTNDEVVDSNGNVVYSYSDLEKG
                     LRNLATQLPGSHQEIANVAEAAGQLGIKTENVVSFTKTMIDMGESTNMSAETAATSLA
                     RFANITQMSQKDFDKLGSVIVDLGNNFATTESEITEMGLRLAGAGKQIGMSQGEILGF
                     ATALSSVGVEAEAGGSAFSKVMIQMQLAVEKGFGAFDQLKQMAEEQGVPWVNLVNAVR
                     DGGKSLKAVSEQMGFTSSDLKKMYKEADNSKSSLENFANVAGVTSEQFQKLFKSDPSE
                     AIIKFIQGLKDSEKHGTSAIKVLDDMDIKEVRLRDSLLRAANASDIFKGAIEKGNGAW
                     KQNTALTNEANKRYETTESKLKILKNEVIDTAIDLGGPFVDALRDGLNVSKPLIKNLG
                     NMAKAFSAMSDDQQRNIIKWVGLAAAAGPALKLLGTGTSVIGKVTSTTGRLTKSLVDL
                     AAKAAEKKAMDAFASSVTTAGAAAAKTAGAGGIGGLVPMMGKTASAASTAAGASGIGA
                     MTTSLGLLGPALLGIVGVGGALAVGYGAWKLFGEEAWNSSQRVKQWGTDVGEEIDSTL
                     DGVQKNIEGANGQFGLLKEGFTVDDANNMAANFATAGTSLETSLTGRIKALDDALKGL
                     PQSVQDAMKEVAESEEETLGQSLSKIKDNNEEIKKIRERAANQNRDLTVSELQQIQDL
                     MKGTSQAYVDTLDVSAKDRKKILSAMNGDVAQATEEEAKTWLQSLAKQKAATTENYRQ
                     MLEEKKAALKEKGVSKEFIDALEDEMNDYIKTTNQGFDSQIAAITNKYPQLINEVSLS
                     NGQLFSKTAAAMDNTGQYTKVFLESNEKILAQAKKTSDEIADNAEKNAEQLGMVADEA
                     THAGSTWNGLVLDEKTGKVKTNVQEVVNEATKDFTKWNELKPVVHDAKLTTNAKDVIS
                     IAAVQNGYWDDMEWKEKEALLEDECSKNVYKALENAGKWNELDIPSKEAILTSNTPEV
                     MGETLMNLGLWDTYKLQVKDLDLNAYKVYDAIDGSEEKLNSWAQLDNPTKELLLDNSD
                     FSTKLFNSEEMFKRWNQLSSNAKFLSANNTKFTEVLLSSDRMWNQWVNLPDNEKRLLA
                     DNEDLATTVLSSEEIYGRWTQLPDNQKYMLADNTDLANKIFASEESWNAWKAIPDTVK
                     NLLGNNIDLLAKVKDGTVSVEEYNKVMPLLKTLYGDNVNLKEAISGAKSSIENYNKNI
                     FPSDKTAVGHDEASQAAKDAFEAFNIFQTKIPDKITKTVSADFIGPMPKNAKGTNFHP
                     GGAAMVNDQKGPTYEELITLPSGETFIPKGRNVVLDLPRGSKVLNATKTKRLVPKYAD
                     GIGNITTVSSTLNLDALILAINELTTVLRTQLMAGTTDAKDTKLSDETKVADPIIPDS
                     LSEKSDQYLGIGAQWLTNLMNGWNSAVPQYMNSEMVFITNYLNALKLQNNPNYTQGAT
                     WNKNLLNGWNSLTGTFIATINSFCNQAMVTLRNYNTPMYNNGRTWQQNNLNGWNSLYG
                     SFIARVNQLGNDSINNLRSKSGGFYNAGTFLLQSLINGMNSLGNSLSTTMNNVANTMV
                     GGIGKGVNGVISGVNYVLKEVESSKNIGNWPIPQYAKGTDGHPGGLAMINDQKGLVHE
                     EYVQMPDGRSFIAKGRDLLVNLPKGAQVLNASLTKKLKERLNIPHYEKGIGNLDIVDL
                     LDDEKRMLEFLTSKVDFSGINEPWLDMTKSGTSLMSKAANTMLQSKLSEFFTHGNFDG
                     AVNANGVYQYLVDVAQKVMGKFPGLTVTSGYRAGDAYYHGKRQAIDLAYPGISGDPRY
                     TAAANYAFEKFPSKIAYVITNGRVRDRMGLSGTRSSGQWTNWPDGDHFDHIHLNGSMG
                     SGDIFNGGVGGSGVARWRSYVSKALKMNGLPATAAYINAWMSQIQTESGGNEKAIGGN
                     DGLAEGNATGLLQTKPGTFAANAFPGHGNIMNGFDNMLAAINYAKKRYGVAGMLQVIG
                     KGHGYANGGLITKDGLYRAGEGNKPEMVIPLTRKTRAIELMGQALAFLSGSNKKETKS
                     EINSVDNRHILQAIEKQSRMTNDLLSLLLSFFKSNNRSDKELALDIQKILIRRT"
     gene            17281..18153
                     /locus_tag="L7C88_001503"
     CDS             17281..18153
                     /locus_tag="L7C88_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HBP9558340.1"
                     /translation="MRTVILRNKLNEEIDLSTEDYFATEMSNLGFEVTKEHIGQWGSF
                     REIGESIELSEFQSSVMISVHGFREQQLYGSLVEFLANGPFELEFSFDSETMIRKCSL
                     KSLSKTEIDSQSSLLTDTLNLYFTSSWYSIKREKLIQNSTSLNTRGKVYSFVRPYVYT
                     KNVWEKKGVFKFSNNSVYLTNSTERMSPLKIRIIGECSNPYWEVIQNSKVVASDGYFI
                     NMKDTQILEVSSLLEDQTAILKDVGGVESSVYQQQDFTKSNFVQAPLGEFSVVFHVGH
                     ANVEIELYEERDLF"
     gene            18150..19199
                     /locus_tag="L7C88_001504"
     CDS             18150..19199
                     /locus_tag="L7C88_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558341.1"
                     /translation="MILAITLFHRDMNLYNERLISTEFEFGTDEIGEEVSNFITDKYV
                     HVKSGDFLLAKFIPSGKIAYFGVISSQEDKKINCKGLLSLADSEIPTVKISGANYEEH
                     IRRLIEYYLLNDPTKQLKNILEVKTESVTSHSYQAVDTNKRRLNAYIINGFKKYNVKW
                     YVKEIKGKKIYTGIRAVDDSIYIKDNSSEFNDWDVFVQSPGPGNENKLLIVDKAMKDI
                     ENPLVLSTWYLDDENNLTQDSTNKNIALPTVNLVNIYDQTQEDRPSYEEVAKSELKGN
                     AYSHEIKVNVVLNARNINVENIETGMLATIVYKEQTYKSVLTAWRISSSKKNIELTFG
                     NVRSRFMDYFEDNGG"
     gene            19203..20027
                     /locus_tag="L7C88_001505"
     CDS             19203..20027
                     /locus_tag="L7C88_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558342.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVNSTGSTVSISKISDSYELTLS
                     KGEILWRGTALMHDTQTVQPSKKIWQTVSGFLLVWLPYENGQAIEDRYVTTPFYKERI
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            20045..>20682
                     /locus_tag="L7C88_001506"
     CDS             20045..>20682
                     /locus_tag="L7C88_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBP9558343.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDKANNRIDQTNQQIGDLGKLKKMYSNSI"
BASE COUNT         7407 a         3122 c         4430 g         5723 t
ORIGIN      
        1 atacatcaac agctggttat gcgcttgcgg aggtacaaaa tgaatcatga gaagtttatc
       61 gaaaaatgca aggctattgt acgtgaaaga attgaaaatg agattgctga cctaagtgga
      121 gcagtgcctg agtttagtat tttcatagtc tggtcatgca aaacactgca aaatagcaaa
      181 gcattagtca gcgctagctt aaaaggagca ccgtattttg aaattacgtt gaacggggac
      241 aaaggtgaaa tctatgtaga tacttatctc aaaaaatcaa atgaatgtat caaagtctag
      301 caggtgctag gctttttctt tacataaagg aggctgcata atgagaaact actggtatgt
      361 atcactaact aatgaatatc ctcgaaccat tggtgattgt tcagtgcgtg ttgtgcgttc
      421 tgtacaaatc aaagggaagt actctattgt cgaaatgcta agagaagcta caccaaacga
      481 agtggataaa tgcaagctga tatattgcgg tcatggctat tggaaagacg agtatatcca
      541 atacaacatt gagaggtaca tcaaatgaat gataactatg attacatcaa gttgattgag
      601 aagataagag cagagaaaga tatggatgaa ctagctacct tattcatgaa catcattagc
      661 ttggtggggt taaagatgga tgaagtagca gcactaaatt atttcatcgc tgagcaaaca
      721 attagagcag agcacaatgc taagttcttg aaagatagac tagatctaga tgtaaaagga
      781 ttaggcgttg aagggatatt caaagtgcaa gaagccttag tgaatgttta tgtcgaaaag
      841 atgcaatagc attgacaagt aattattgga tgttttcagg agggaaacta tgaaattaaa
      901 agattatatt agggaagggt ataacattgt aactacacca aatctagctt ataaaatcca
      961 agaagattat cccgatgctt tagtgtttac tgatagagct ttagatgcca ttcctatagg
     1021 gaagttatta gttgatcgtt attatagcaa taatccagct gttcttagtg ctaagccact
     1081 tcaaaacgct tatgctattg aacgctttac ttgcgagttt actggatatg agacggtagt
     1141 accaatgaca ggtgagacag gaagaaaagt aattcaacag atcaaaaaga ggattgctga
     1201 attgacgtta gatgatggaa gtaatacgaa ccttctagaa atcaaactaa gagatactga
     1261 ctcagtacca gaagtttatt ataaaggtca acgaatggat gagatgccga taggtcttgt
     1321 cgatattact tatcattggg atacggaaga atatgaatgc caagtaccaa aaggagctaa
     1381 cgacatcact attgaatatt atgattcaca taataacaag tacttagata gaaaaatcat
     1441 tgggcacaag agagatatgt aaatgattga tgtttcaagt aaacaagcaa gagctaggtt
     1501 ctatggatca actgagtgga ggaaacttag aagtcaatgc ttagagcgag atcattatga
     1561 gtgccaatgg tgtaaagcag agggtagact aacaactcaa catgattcaa ttcttgaagt
     1621 ggatcatata aaggagctgg agtatcatcc ggatttagct ctagatataa acaacctaag
     1681 aaccttatgc aaagattgcc ataacaaaag gcacaaccgt atgaaatatc gtggccaaca
     1741 aaagaaaaga aagtgggatg atgaatggtg gtaagaaaaa cagcaaacag agatgatgtc
     1801 aaacgagcag aagcaatcgc tatggttgat aaggctattg ataagttggt tctatttaag
     1861 agtcagctca ttgaaggaac aacaactgta gaggatatat ctatcaacaa tagactaata
     1921 ggtaacgcta atgaagtaac agggacattt aatattaatg tagacattga ttataccttg
     1981 agtccatttg cacatattgt agaaagcaac gagcaagacg gctgataaat cagtataaag
     2041 cgaagatata tagagtgaaa tacccccggt caaaagattt tgagaagaaa taaaattttt
     2101 gggaaccggt ggatggggtc aactctgcaa ataaatgatg ctattttcac acgaccccct
     2161 ccccacgtag aaaggaagtg agttgatggc tgatctgcaa gagagaaata ggcttgtttc
     2221 tgctgaagaa aggcgtctaa ataaattgtt taaggatatt gataaggata aaaagaaggt
     2281 cgtttctggt ttgattacgc aagcggcacg cttaaaaatt cttcttgatg aaatgtggat
     2341 tgatatttcc gaaaaaggtg attatgagct tttctctcag tcagaaaatc aaaaacctta
     2401 cgagcgggaa cgaccagttg ctaaacagta taattcgaga gaccaagcat atcaacgtgt
     2461 aattaagcaa cttactgact atttgccaga agaaaagcgc gaacctacaa aaaatgcagc
     2521 gctagatggt agtgatttgc tgtgacaaca ttaaagccat tctattttga tgaatacgta
     2581 gatttatacg aaaaaggggt aatccctttt aataaagaaa gaattcagtt aattacttat
     2641 ttaaaaaacg aagtgctagt tcgggatgat atctattttg atgaagaaat gattcaaaag
     2701 tttatcaagt acactgaaaa aaattttttt cctttagcta aatatcaaaa atttatcaca
     2761 cctttcattt tctgctatca aaaagaggac gacgaggtgt tttttgatga aattctaaat
     2821 agtattgcgc gaggcggcgg gaaaaatggg ttcatgtcag caagagactc attttttatt
     2881 agccctctct acggtgtcag aaattatgat gtaacgatta cagcgaattc tgagaagcag
     2941 ggaaaggtat cttttaaaga agtttatgaa atggtacaaa tgcgcaaact ggaaaaacaa
     3001 ttttatttga ctaagatggc tatagtcaac aatgtaacta attcgatttt tagttatagg
     3061 acaaacaatc ctaagactat ggatagtgca agagatggct gcttagaatt tgatgaaatc
     3121 catcagtttg aatcttcaga cctagttgat attcagcgta gtgggctagg gaaaataaaa
     3181 catcctcgaa ctttttataa tggtacaaat ggtcatgtta gagaaggttt ttatgacaaa
     3241 atgttggaac gagcacaaaa gatttttagt ggagagaaca agaatgatcg cttgtttccc
     3301 tttatttgta aactggataa cattgatgaa atggataatc ctaaaatgtg gtcaaaggct
     3361 aatccaatgt tcgaagaaga ttcagcatat tcaaaacgtc tgttttctac agtgatgaaa
     3421 gaatataaaa aactagaaga tgagccatca ggtaggcgtg aatttgttgt taaacgaatg
     3481 aattttacag aaggtgatgc agaatcagat attacgactc atgaaaaatt aatggctact
     3541 aaacaagaat tgccaaattt gaatggtcgt tcttgtgtgg ctggatttga ttatgcaagt
     3601 attcgtgatt ttgcaacagt gggtttgctt tttaaaattg atgataaatt tatctggcag
     3661 caacatagtt ttgctaggaa aaagtttcta gatacattca aactgaaagc gcctattaag
     3721 gattgggaga aaaaaggttt agtgacaatc gttgatgagc catcaattga tcctcgtcat
     3781 ttaattgatt ggttaaatga aaaaagaaaa atccatcaaa tagaaatcgt ttgtgccgac
     3841 ggatttcgta tggatttgct gaaacctctt ctagagaaag aatcatataa ttttgagttt
     3901 atcagaaata taagaggtgt gcagtcaaaa gttgctccta ttattgaaga tggttttgca
     3961 aatgaacggt ttatttttgg tgatgatcct atgatgcgtt ggtatacaaa taattcgttt
     4021 atcaaagaag acaaattagg gaataaaaca tttttgaaaa aagagccagt aaggcgtaaa
     4081 acagatgggt ttcatgcttt tttggcagct ttatataaac gagaagaaat aactgatatg
     4141 gattatgagg aagcatttga tatgttggat gagattgaat tttaatgaaa ctaagctcta
     4201 gaaatagggc ttttttattt ttctttgaaa ggtggtgaaa acatgtgagc ttatttgata
     4261 tctttaagca gtcaataaga aatgaagagc cttctgagtg gataccggat tttgtatatg
     4321 gagaggaagt atctgctcgg gcatacctca aaattatggc aaaaaatact gttttagatt
     4381 ttgttgcaag aactatgtca acgttagaag ttaagtttaa aaataaagat gggacatcag
     4441 actgggatta tattctaaat gttcgaccta attctgatat gtcagcagct acattttggc
     4501 aaaaattttt ttatcggctc ttagatgaca acgaagtgtt agtaatattt acagatgata
     4561 atcaattgct gattgctgat gattttagtc gaacggagta tgccgtgtat gatgatgttt
     4621 ttacaaatgt gatggtaaaa aattttgtct ttgaacgttc atggaacatg tctgacgtca
     4681 tttatatgga atataataac gaagaattag aaaggtttac acgaggttta tttgaagatt
     4741 acgccgcgtt gttcggacgg attctagaag ttgcaatgcg taacaaccaa attcgtgggt
     4801 ctgtatccat tgattcaacg ggaacggcga atgatgaaaa aggaaaagat ggtaagacta
     4861 gatctcaaag attacaagaa tatattgata ggatttggaa ctcttttaaa actaactcag
     4921 ttgcaattgt tcccaaagtg aaaggctttg agtatgagga atacaccaat aaacaaggcg
     4981 tatcgaatca atcgctagat gaactgaata agatgaagtc gtctttaatt gatgatgttg
     5041 ccaacgccat aggagtacct acggcgctta tttatggtga aaaagctgaa ctggattcaa
     5101 atattaaagc ttttcgtaaa ttgtgtattg ctccactagt taaaaaactt caagacgaat
     5161 tggtggtaaa aataattagt cgtcaagagt acaaaaacgg ggaacgtata gaagttaaaa
     5221 aagttctcca aaaagatcta ttagagtatg ctactcaaat tgataaaata acatctggtg
     5281 gtgcgtttta tattgacgaa gttcgtgatg aagttgatta tgatgagttg ccaaataatg
     5341 aaggaaaaat tcgtattcgt acgaaaaact atgaagaaac tgtgaaggga ggtgagaacg
     5401 acaatgccga aagctaaaaa agtaccattt cagtttacta acgaaattca gaatggtaag
     5461 cacattctca ccttgagtgg aaatgtacag aaaaaatatt ggcgtgatga tgatgtcata
     5521 aacgctaaag atattcgtga ctctctagat actgtaaccg atgatattgt aatcaagttg
     5581 aacagcccag gcggtgatgt gtttgaaggg attgagattt acaattattt aaaagatcac
     5641 ccatcaaata ttactgtaga agttacaggg cttgccgcaa gcgcagcaac gtttattgtc
     5701 gctggtgcca atgatgtgat tatgaatgtt gggacttctt tgatgattca tgaagcttct
     5761 acatttgctt gggggaataa acaggacatc caaaaaacgt taaacgcatt ggaaacgatc
     5821 gatgattcta tcttagctat ttattcagat aagactggcc aatctgttga taagttgcgt
     5881 gaatggatga atgaagaaaa atggtttaca gcagatgaag ctgtcaaata tggatttgcc
     5941 aattctgtga agcgtgaaga accacaaaat gaacctcaaa atattgcagc gatgattcaa
     6001 gatgctgttg ccgttgcaat agcgaattta aaggaacctg ttactaataa aatcgaacaa
     6061 gaatcaaaac aaaaatcatt aatcgcacga ttgcgaaaag gagaataaag atatgttaaa
     6121 aattacagat aaaactgcag atgcaaaaaa ggcatttaat gctatttctt cgaaagaaga
     6181 tgcaacaccc gaacaaatta atgctgctct agaagaatat gtaaccgcca ttgcagaaga
     6241 tgccggcaaa caggtgcgtg ctgaatatga agaattgaaa aatgtgacgg acaaccgtgt
     6301 attagaggct cgtggaattc ctacactaac agcagaagaa acaaagtttt ataatgaagc
     6361 cgtaaaatct ggaggtttcg attctgacgt agtttggcca gaaacgattt tggaacgtgt
     6421 ttttgaaaat cttcaaaacg atcatcctat tttaggcctc attaacttta caccaactgt
     6481 aggtcgtgtc aaagtaatta gagcacgtcg taaaggtgtt gctgtttttg gaccattgca
     6541 taaagacctt gaaggccaac tagatgctga atttggtgca actgaatttg ttcaacttgc
     6601 gttgaccgca tttttcttaa tttctaatga taccttagat ttaggaccac gatggattga
     6661 ccgttttatc aatctttctt taagtgaagc agtacgtgat gtttgggcta aaaaaattat
     6721 tacaggttct ggtaaagatg agccaattgg attgcttaaa gatctagatg gtgcggtcac
     6781 aagtggtgta tatccagata aagctagcgc agggacatta acttttgcga aagagaagat
     6841 tgttcttgaa cttgcagggg tgatgaaaaa attatctaaa tacacataca aagtagatgg
     6901 tgacgatgaa ggtgaagtga aataccgttc tgttgctgga cgagtgtatc taattgttaa
     6961 tcctgttgat tactgggata tcgtagctag agttacattt gcaaatttaa acaatgtgta
     7021 tgggactacg atgccattta tcgctgttga tcatatcatc gaatctgtag acgtaccaga
     7081 aagtaaatgt attgcatacg ttgataaaga gtatgaagct actcaatcaa gagctgaaaa
     7141 agtctatgta tataaagaaa cttttgcaat gaaacgcgca actttgtatg ctgtcgacat
     7201 gcttggtaat ggctatccaa caaataatga tgcagcacaa gtatatgact tggactttac
     7261 agcgggggag taatgtcccc tgcaattggt gagataacac cgacgactga tggggcagtc
     7321 attaatcttt cgtaaatggg gttagagtat gaacactgaa gaatttataa aagaatataa
     7381 ggcccgattt cgtattttcc atacttccga agatgaggat atcgggaaac agttagagag
     7441 cgggtttgcc gatataaaat ctctaatcgg cagttttgat ccttccactt atgagaaagg
     7501 aaaagaatta gtttatgaac gtactcggta tctacggaac gaatcactag agtactttta
     7561 cgacaatttt caaacaatga ttatggatgc atcaattgat ctggcaggtg ctggatatgc
     7621 caattaaatc aaattataag aagcctaaaa ttgtagctgg tgatctaaat acgccagtta
     7681 ctttttttga gtttcaacct aataagggtc cagaacctgg tgatgaagaa aaaaaggaac
     7741 tgtatttttg tacagcacta gtttacaacc catcaatgaa agatcgtgac attcttggca
     7801 caaaagaagg cgttacgata aaaatacggg atccccatca atcttatatt cctactaaca
     7861 aacataaagt aaggatatta gattatcgat atggagataa agtttgggaa ataatcgatg
     7921 tctcaccgga tttggaagaa aattcaattg taaagatagt attagaatta attacttaaa
     7981 tttggtgata aatgatgagt aacgtaaagt ttgaaggcgt tcaagaaaca atccaagctt
     8041 tagaaaaaaa gtatggagaa aagaaaacta agacattaac aaaaaaagca atcaatgttg
     8101 gcgctgaaaa agtagaaaaa cagttgcaaa cggacatgac cgtttttaaa gacaaaggtt
     8161 atacgatcgc tgaggttgtt cgcaagaacg ctacgtatag agattacaag gcagaagctg
     8221 aaatcggttg gaatggtcca catcaacgat atagaatcat tcatttgaat gaatggggat
     8281 atacacgaaa gggcaaacaa attagaccga gaggatttgg tgtaataaca aaatctctta
     8341 agaattccga gctgttgtac tttgatgctg taggagagga ggttaaaaag agtttatgaa
     8401 agatatgctt aatatcattt acgaggctct ttgtttgaat gagtatattc attcaatgac
     8461 ctacaacgag aataccgagc aatatcgtat taaattttat gagcaacctg aaaccgccga
     8521 taaaacaggt ccaatgatca caattcgtcc tgtagataca cctaacgaag cgtaccacgg
     8581 aagtaacaaa gagctttctg tggagcatat gatacagatt gacgttgaat cgaaatatag
     8641 agcaacatgc aagcagattc aatatgagat aaaaaaagag atgaaaaaac taggctttgg
     8701 ccaaatttcc ggtcaagggt tagatgaata ctttactgaa acaaaccgct ttgtagacgc
     8761 gcgtcgttac gaaggaaata caaaaattta cgataccgaa tattagaaat taagacacga
     8821 aaataacgtg tcttttttta ttacccaaaa ttaggaggaa aattttatga ctttagtagg
     8881 attcaaaaaa atgacaatcg gggtctttga cagcacaggg aagattccag cagcaaattt
     8941 atatgtaatt gaaggtgaac aaaacaaagg ggcgactgta tctgctgaaa tcagtgggct
     9001 atcaaaagaa ccatcaaaag tttacggatc gaacatcgct tactatgtct ctcaaaaagg
     9061 aacaggcgat gtttcagcta cttttggatt gttagattta ccaaaagaag taaatgacaa
     9121 aattcttggt tacaaaaccg atacaaacaa aatcagcttc ttgggagaag atactgagcc
     9181 accatattgt gcaattttga tggaatcgga ggatttgaac ggcgatacag caatgcttgc
     9241 gatgttcaaa ggaaaattca gacgtgaatc tattaatctt aacactacga caaatgaagc
     9301 tttcgaacca gaagcagaag aatatgtatt ttcagcgatt gccaatgatg ttgaaggtga
     9361 tgctaaaggc caaacagtcg caaaatatgt tggagacgaa gaagcttcta ttactggttt
     9421 gaaagagatg gtatttcctg cagcggggga gtaactagcc ccgttgttgg agcaatcact
     9481 cccactatta atggggcaac agttgaatta agttaggagg ataactatgc cagatacatt
     9541 taaaatctat aaaaaaaatg gtactgaatt tacaaaagtc gcagagggtg aaagtccact
     9601 ttctattact ggaattgcag caaatactca agttgctaaa ggagattatc aagctacgcg
     9661 tgtggtcgga ggtcaagaat cagtaaaagt agatattcct gcattcacca ctcttccaat
     9721 ttcagttact ggtgtgacgt tggataaaac gacagctgaa gttgaacaag gcggaacctt
     9781 aaaattaact cctactgtaa caccagcaaa tgcaacagac aaaacaggaa gctggagcag
     9841 ttcgaataca gctgtagcta cggttactgg aggcaacgtt acagtaaaaa cagacgctga
     9901 agttggcgga actacagaag tttcatttac tactacggat ggcggtaaag tagcaaaatg
     9961 tactattaca gttattgaaa aagcagcggg ctagtcttcg gactagcttt tttatttgga
    10021 aaataatgga ggaatctaaa tggcaaaagt aagaattgaa ttgaaagaag aatcaggaaa
    10081 gaaagtctat gaaaacatag acacaacagg gaaagattat cgaaaagctt tagaaacaat
    10141 caaaaagcta aatgaagacg gagtaatgat ttggaatcgt ttagacattt atttggattt
    10201 tgctgtaggt atcttcaggg atagcaaatt gacagctgaa caaattcttg atggcttacc
    10261 atctgagaag gtaatgagca cattggacga catcctagga gaagtaatgg ggattgaaag
    10321 taatccagac ccagacgcaa aaaagtaaca cccgaagaag cagaagaaat gtacttaaac
    10381 ctatgcagag agttagtgaa agcgggatgg tcactatctg acatagaaga taattccttt
    10441 gaaatgatga tgaaaattgc gtgcacttcg cctaagaaag agaaacaaaa agaagttgat
    10501 cttaaagact tcttgaaatc catgtagaga ggaggtaaac atatggcaaa tggaaaacct
    10561 ttaggcaata tgattatcaa actagactta gacagttcag ctttttcaaa aggtctagcc
    10621 ggagctaaaa acgctgttaa ccatcaaatg aaagcaatga aatcacagat gcaagtaatg
    10681 aactcttcag gaaattctct cggtgcttta caagcaaaat acaatggttt aggcggagtt
    10741 ctacaagcaa atgaaaagca agtagaattg ctcactaagg cttataagga tagttttgac
    10801 tctaacggaa acgctactgc ttcgactgct aaatacgcta atcaattgaa tcaagcaaca
    10861 gctagatcag caagttacga atctcagatg aaaacaactg ttggacagat tgctcggatg
    10921 aaagtggaaa cggaagggtt tacggggaaa ctaaaggcta attctgatgt attgattaat
    10981 tctgggaaaa aaattgaagc ctttggtaaa ggagtttctg ggataggatc tgccctaact
    11041 gttggagtaa cagctccaat agtggcaggc gcaactgctg ttactagtgc agctatttca
    11101 tgggaaagtg cttttgcagg tgtaaaaaag acaaatgatg aagttgtaga ctcgaatgga
    11161 aacgtagttt attcctatag cgacttagag aaaggtctgc gtaatcttgc cacccaatta
    11221 cctggtagcc atcaagaaat agcaaatgta gccgaagcag ccgggcaatt aggtataaag
    11281 actgaaaacg tagttagctt cactaaaacg atgatagaca tgggtgaatc gactaatatg
    11341 tcggctgaaa ctgcggcaac ttctttagca cgatttgcta atattaccca aatgtctcaa
    11401 aaagactttg ataaattagg atcagtcatt gttgatctag gtaacaattt tgctacaacc
    11461 gaatcagaaa tcactgaaat gggattgcgg ttagcgggag ctggtaaaca gattggaatg
    11521 agccaaggcg aaattctagg atttgctact gctctatctt ctgttggtgt cgaagctgaa
    11581 gcgggtgggt ctgccttttc gaaggtcatg atccagatgc aactagctgt agaaaaagga
    11641 tttggcgctt ttgatcagct gaaacagatg gcagaagaac aaggtgttcc gtgggttaat
    11701 ttagtaaatg ctgtgagaga cggtggaaaa tcgttaaaag cagtatcaga gcaaatggga
    11761 ttcacttcat ctgatttaaa gaaaatgtat aaagaagcgg acaattcgaa aagttcgctt
    11821 gaaaattttg cgaatgtggc aggtgttaca agtgaacaat tccagaagtt gttcaagagt
    11881 gatccttcag aagcaatcat caagttcatt caagggctga aagattcaga aaaacatggt
    11941 acttcagcaa tcaaagttct ggatgacatg gatataaaag aagttcgact acgcgacagt
    12001 ttattgagag ctgcaaatgc tagtgacata ttcaaaggag caattgaaaa aggaaacggc
    12061 gcgtggaaac aaaatacagc tttaacaaat gaagctaata aaagatacga aacaactgaa
    12121 tcaaagctaa agatattgaa aaacgaagtg attgatacag caatcgatct tggaggtcca
    12181 tttgtagacg cgttgcgtga tggtctaaat gtatcgaaac cattgataaa aaacttaggg
    12241 aatatggcga aagctttctc agctatgagt gatgatcaac aaagaaacat tatcaaatgg
    12301 gttggattag cagcagcagc tggtccagcg ctgaagcttt taggaactgg tacttcagta
    12361 ataggtaaag ttacttcaac tactggaaga ttgacgaaaa gccttgttga tttagcagcg
    12421 aaagcagcag aaaagaaggc tatggatgcc tttgcatcgt cggtaacaac agctggtgct
    12481 gcagctgcaa agacagcagg agctggaggt attggcgggt tagtccctat gatgggaaaa
    12541 acagctagtg ctgcaagtac tgctgcgggc gccagcggaa taggcgcaat gacaacgtca
    12601 ctaggtttgt taggtcctgc tctacttggt attgttggcg ttggtggcgc actggcagtt
    12661 ggctatggag catggaaatt atttggtgaa gaagcttgga attcctcgca aagagtaaag
    12721 caatggggaa cagatgtcgg tgaggagata gatagtactc ttgacggagt acagaagaat
    12781 attgaaggtg caaatggtca attcggtctt ctcaaagagg gttttactgt tgatgatgca
    12841 aataatatgg cggctaattt cgcaaccgct ggaacatctt tggaaacatc tttaacgggt
    12901 agaataaagg cattagacga tgcactaaaa gggctacctc aatcagttca ggatgccatg
    12961 aaagaagtag ctgaatcaga agaagaaacc ttagggcaat ctctttctaa aataaaagac
    13021 aacaatgaag aaataaaaaa aatcagagaa agagccgcaa atcagaacag agacttgact
    13081 gtttcagaac tacaacagat acaggatcta atgaaaggaa cttctcaagc gtatgtggat
    13141 acgctcgatg tttctgctaa agacagaaaa aagatactat cagccatgaa tggtgatgtt
    13201 gcacaagcta cagaagaaga agcgaagacg tggttacaat ctttagcgaa acaaaaagct
    13261 gcaactaccg aaaattatag acaaatgctt gaagaaaaaa aggcggcttt aaaggaaaag
    13321 ggagtaagca aagaattcat tgatgcatta gaagatgaaa tgaatgatta catcaaaact
    13381 acaaatcaag gattcgatag ccaaatagct gctataacaa ataaatatcc acaattgatt
    13441 aacgaagtga gtttatcaaa tggtcaatta tttagcaaaa cggcagctgc tatggacaat
    13501 actggtcagt atacaaaagt ttttctcgaa agtaatgaaa agattttagc ccaagcgaag
    13561 aaaacatcgg atgaaatagc agataatgcc gaaaaaaatg cagaacaact tggtatggta
    13621 gctgatgagg ctacgcatgc tggatcaact tggaatggct tagttttaga cgaaaaaaca
    13681 ggaaaagtaa aaactaatgt acaagaagta gtgaatgaag caacgaagga tttcactaaa
    13741 tggaatgaat tgaaacctgt tgttcatgat gcgaaactaa caacgaatgc aaaagatgtc
    13801 atttccatag cggcagtaca aaatggctat tgggatgata tggaatggaa agaaaaagaa
    13861 gcattattag aagatgagtg ttctaaaaat gtatacaagg ctttagaaaa tgctggtaaa
    13921 tggaatgagt tagatattcc ttctaaagaa gcaatcctaa cttcaaatac tcctgaagtt
    13981 atgggtgaaa ctctcatgaa tttgggatta tgggatactt acaaacttca agtgaaagat
    14041 ttagatttga atgcgtataa agtatacgat gctatcgatg gatcagaaga aaaattaaat
    14101 agttgggctc aattagataa ccccacaaaa gaattgttat tagataactc agatttttct
    14161 acaaaacttt ttaattccga agaaatgttt aaacgttgga atcagttatc atctaatgca
    14221 aagtttcttt cggctaataa tactaaattt acagaggttc ttttatcatc tgacagaatg
    14281 tggaatcaat gggtaaacct tcctgataat gagaaaagat tacttgcaga taacgaagat
    14341 ttagctacca ctgttttatc ttcagaagaa atatacggaa gatggactca attaccagat
    14401 aatcaaaaat atatgttagc tgacaatact gacttagcaa acaaaatatt cgcttcagaa
    14461 gaatcatgga atgcatggaa agcaattcca gacacagtta aaaacttgct tggtaataat
    14521 attgatttac tggctaaagt gaaagacggg actgtaagtg tagaagaata taacaaagtt
    14581 atgccacttc ttaaaactct atatggagat aacgttaatt taaaagaggc aatcagtggg
    14641 gctaaaagct ctatagagaa ttacaacaaa aatatttttc ctagtgataa aactgcagta
    14701 ggacacgatg aggcttcaca agctgctaaa gatgcatttg aagcgttcaa catcttccaa
    14761 acaaaaatac cagataaaat tactaaaact gtatcagctg actttatagg tcctatgccg
    14821 aaaaatgcga aaggaacaaa cttccatcct ggcggagcag ctatggtaaa cgatcaaaaa
    14881 gggcctactt atgaagagct tataaccttg ccaagcggag aaacttttat acctaaagga
    14941 cgtaatgtcg ttttagactt accaagaggt tcgaaagtac tgaacgccac taaaactaaa
    15001 cgtctagtgc ctaaatatgc tgatggtata ggaaacataa cgacggtttc atctacgcta
    15061 aacttagatg ctttaatttt agctattaac gagctaacga cggtattgag aactcaactg
    15121 atggcaggaa cgactgatgc taaagatact aaactatcag atgaaacaaa agttgccgat
    15181 ccgattattc cggacagtct ttctgaaaaa tcagatcagt atctaggaat tggagctcaa
    15241 tggttaacta atctaatgaa tggttggaac tcagcggttc ctcaatatat gaatagtgaa
    15301 atggttttta ttacaaacta tctcaatgcg ctaaaacttc aaaacaatcc taattatacg
    15361 caaggagcaa catggaataa gaacttactg aatggatgga atagtttaac tgggaccttt
    15421 attgctacaa tcaattcatt ttgtaatcaa gcaatggtca cgcttagaaa ctacaacact
    15481 cctatgtaca acaatggccg aacgtggcag caaaataatc ttaatggttg gaattcattg
    15541 tatggatcat tcatagcccg tgtaaatcag cttggtaacg attcgattaa caaccttcgt
    15601 tctaaaagtg gtggttttta caatgcaggg acattcttgt tgcaatcttt aataaacgga
    15661 atgaattcgt taggtaattc tctttctact acaatgaaca atgtcgctaa tacaatggtt
    15721 ggtggtatag gcaaaggagt taatggcgtc atatcgggag ttaactatgt gcttaaggaa
    15781 gtcgaatcaa gtaagaatat cggaaactgg ccaattccac aatacgctaa gggaactgat
    15841 ggacatcctg gtggacttgc tatgattaat gatcaaaaag gcctagttca cgaagaatat
    15901 gttcagatgc cagatggacg tagttttatt gccaaaggta gagatcttct tgttaatttg
    15961 cctaaaggtg ctcaggtctt aaatgcttct ttaacaaaga aattaaagga acgtttaaat
    16021 attccacact acgaaaaagg tattggcaat ttagatattg ttgatttgtt agatgatgaa
    16081 aaaagaatgt tagaattctt aactagcaaa gttgattttt caggcattaa tgaaccatgg
    16141 cttgatatga ctaaatcagg aacgtcatta atgtccaaag ctgcaaatac aatgcttcaa
    16201 tcaaaattaa gtgaattctt cactcatggc aattttgatg gtgcagtaaa tgccaatggt
    16261 gtttatcaat atttagttga tgtggcacag aaagtaatgg gtaagttccc cggacttaca
    16321 gtaacttctg gatatcgagc aggagatgcc tactatcacg gaaaacggca agctatcgac
    16381 ttggcttatc caggtatttc tggagatccg agatatacag cagcagcaaa ttacgctttt
    16441 gaaaaattcc cttcaaaaat tgcgtatgtc attacgaatg gacgtgtacg tgaccgcatg
    16501 ggattatctg gaacaaggtc aagcggacaa tggacgaatt ggccagatgg cgatcacttc
    16561 gatcatattc atttaaacgg ttcgatgggg tctggcgata tattcaatgg aggagttgga
    16621 ggaagtggtg ttgcacgctg gcgttcttat gtgtctaaag cattgaaaat gaatggatta
    16681 ccagctacag cagcgtatat aaatgcctgg atgtcccaaa tccaaacgga atctggtggt
    16741 aatgagaaag caatcggcgg caatgatggg ctcgccgaag gcaatgcaac aggattactt
    16801 caaacgaaac ccggaacttt tgcagctaac gcttttcctg gtcacggaaa tattatgaac
    16861 ggatttgata acatgttagc agcaatcaat tatgctaaga aacgttacgg agttgcaggt
    16921 atgttgcaag ttatcgggaa aggacatgga tatgccaatg gcggcttgat taccaaagac
    16981 ggactatatc gagcaggaga aggaaataaa ccagaaatgg ttattccatt gacaagaaaa
    17041 acaagagcta tcgaacttat gggtcaagca ttagccttcc tttctggaag caataaaaaa
    17101 gaaacgaaaa gtgagattaa ttctgtagat aatagacata tcctacaagc gatagaaaaa
    17161 cagtctcgta tgacaaatga tctgctatca ttattactct cgttttttaa aagtaacaat
    17221 cgatcagata aagaactagc tttagatatt cagaaaattt taatcaggag gacatagtat
    17281 ttgaggacag taatattaag aaataaattg aatgaagaaa ttgatttgtc cacagaagat
    17341 tattttgcta ctgaaatgtc gaatctaggt tttgaagtta caaaagagca tattggacaa
    17401 tgggggagtt tcagagaaat aggagagagt attgaattgt ctgaatttca atcatcagtt
    17461 atgatttctg ttcacggatt tagagaacaa caattatatg gttcattagt tgaatttctg
    17521 gctaatggac cttttgaact agaattttct tttgattcag aaacaatgat caggaaatgt
    17581 agtttgaaat cattatctaa aacagaaatt gattcccaaa gctcattgct aacagatact
    17641 ttgaatctat attttacttc aagctggtat tctattaagc gtgaaaaatt aatacagaat
    17701 tcaacttctc tcaatacacg tggaaaagtt tactcatttg ttcgaccata tgtctacacc
    17761 aaaaatgtat gggaaaagaa aggtgtattt aagttcagta ataattctgt atatttgaca
    17821 aatagtacag agcgaatgtc tccgttaaaa ataaggatta ttggagagtg ctcaaatcca
    17881 tattgggaag ttatccaaaa ctctaaagta gtagcttcag atggctattt tattaatatg
    17941 aaagacacac aaatattaga agtgtctagt ttgctagaag accaaacggc aattttaaaa
    18001 gatgtaggtg gagttgaatc ttctgtttat caacaacaag attttactaa atcaaacttc
    18061 gtccaagcgc ctctaggaga attcagcgtt gtttttcatg ttggacatgc aaatgtagag
    18121 attgaacttt atgaggagcg tgatctattt tgattttagc cattaccctc tttcaccgag
    18181 atatgaattt atataacgaa cgtttaattt cgactgagtt cgaatttgga acggatgaaa
    18241 ttggagaaga agtaagtaat tttattacag ataaatatgt ccatgtaaaa tcaggagatt
    18301 ttctactagc aaaatttatt cctagcggga agattgctta ttttggagtg attagctcgc
    18361 aagaagacaa aaaaataaat tgcaaaggat tactcagttt ggccgatagc gagataccga
    18421 ctgtaaaaat atcaggtgct aattatgaag agcatattcg acgactgatt gaatactact
    18481 tattgaacga tccaacaaaa caactaaaaa atattttgga ggtaaaaaca gaaagcgtta
    18541 cttctcattc ttatcaagct gttgacacaa ataagagacg attgaatgca tatataataa
    18601 atgggttcaa aaaatataat gttaaatggt atgtcaaaga gattaaaggt aaaaaaatat
    18661 atactggtat tcgagcagtt gatgattcaa tttatattaa agataattca tctgagttta
    18721 atgactggga tgtttttgtg caatctcctg gaccagggaa cgagaacaaa ttattgatcg
    18781 tagataaagc aatgaaagat atagaaaatc ccttggtatt gtctacgtgg tatttagatg
    18841 acgaaaataa tcttacgcaa gattcaacga ataagaacat tgcattgcct accgttaatt
    18901 tagtaaatat atatgatcaa actcaagaag atagaccttc ttatgaagag gtagctaaat
    18961 cggagcttaa aggcaacgcc tattcacatg aaattaaagt taatgttgtg ctaaatgcta
    19021 gaaatatcaa tgtagaaaat atcgaaacag gaatgttagc gactattgtt tacaaagagc
    19081 agacttacaa atctgttcta actgcctggc gaatatccag cagtaaaaag aatatagaat
    19141 tgacatttgg taatgtccga agtcgtttta tggattattt tgaagataat gggggataaa
    19201 aaatggttag caatgtggat ggatatcaat ttgaaaacgt gaaagtaagc gcagaaaatg
    19261 atgctagact ttatcacgtt ttatataatc ggaaaaatca ggttattgat ggttacgatc
    19321 agtctatgaa tttatcttca agcggattaa cagtaaaagt tgctgcagga gcagcgatta
    19381 ttcaaggtcg tatggtcgtt gttcgacaag aagaaagtat aacagttcca gcaaactcaa
    19441 gtggttatat agcattaaca gtggatttga cacaagaagt tatacctgga tctattcttc
    19501 cagaatcgga agaatatgaa tggactaata atcaagtcaa gctagaattt ataacaaaag
    19561 ttataaaagg taatttaaac aatggtgata aggtctataa tttaccacta tgctcagtta
    19621 attctactgg atcaactgtt tcaatctcaa agatatcgga tagttacgag ctgactctct
    19681 ctaaaggaga aattttgtgg agggggactg cgttaatgca tgatactcaa actgtccaac
    19741 cttcaaaaaa aatttggcag acagtttcag gttttttgtt agtatggctc ccatacgaaa
    19801 acgggcaagc aattgaggat agatatgtaa ctacgccttt ttataaggag cgtataactt
    19861 ttactaatgt tttaggagaa attgtttcag gatttgatga ctatcacaaa aagtggttta
    19921 gtaaacgaat aaactataat tcgaatacta atatatttac aggtgcagca agcaatgcaa
    19981 gtggagataa cgcaaatatg gtgcttaggt atatagtttc tttttagtta ggaggtatgg
    20041 aagagtggca aatttagaaa ttaaattatc tgcaaataag agacagcctt atctacgtca
    20101 ccgtgttgtt ggtagagttg gtgatggggg gctcacaaca atcaatgtac aacttcttga
    20161 ggaagatgaa attacacctt ttgtaattaa tctaaacggt actttgaaat ttgtgggcga
    20221 agtttcaaac ggtaactata ccgagggaga accagaaata atcgattcga ctaatgggtt
    20281 aattagttac acgttcacta agtcaaattt cagcacgagt catcaattca aacaagcata
    20341 ttttgaatat gtagatccta acggcaaaaa agtaactttt cagaacttca tcatagacgt
    20401 gttagaacga gtagatatta attcggagca agcgaaatac tatatttctt cattggaaaa
    20461 attacagagt gaaatgcaaa ccactttcaa tcagttcatt agtgataaac aggtccaata
    20521 cgatcaaatc tactcgaaat ataacgaatt agtaagattg ataaatgaat cagataagca
    20581 agtaaatgat cgtattgata aggcaaataa tcgtattgat caaaccaatc agcaaatcgg
    20641 cgatctcggc aagctgaaaa agatgtacag taacagcatt ga
//
LOCUS       DAFTHM010000042        20585 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFTHM010000042 DAFTHM010000000
VERSION     DAFTHM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.042"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="L7C88_001507"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="L7C88_001507"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBP9558344.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="L7C88_001508"
     CDS             1011..2258
                     /locus_tag="L7C88_001508"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBP9558345.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="L7C88_001509"
     CDS             2334..2678
                     /locus_tag="L7C88_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558346.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="L7C88_001510"
     CDS             complement(2795..3121)
                     /locus_tag="L7C88_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558347.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3736..4938)
                     /locus_tag="L7C88_001511"
     CDS             complement(3736..4938)
                     /locus_tag="L7C88_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9558348.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            5055..5570
                     /locus_tag="L7C88_001512"
     CDS             5055..5570
                     /locus_tag="L7C88_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBP9558349.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5769..6215)
                     /locus_tag="L7C88_001513"
     CDS             complement(5769..6215)
                     /locus_tag="L7C88_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBP9558350.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6262..7740)
                     /gene="msr(C)"
                     /locus_tag="L7C88_001514"
     CDS             complement(6262..7740)
                     /gene="msr(C)"
                     /locus_tag="L7C88_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBP9558351.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(8094..8723)
                     /locus_tag="L7C88_001515"
     CDS             complement(8094..8723)
                     /locus_tag="L7C88_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBP9558352.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(8707..9171)
                     /locus_tag="L7C88_001516"
     CDS             complement(8707..9171)
                     /locus_tag="L7C88_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBP9558353.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9658..10926)
                     /locus_tag="L7C88_001517"
     CDS             complement(9658..10926)
                     /locus_tag="L7C88_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBP9558354.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(11157..11894)
                     /locus_tag="L7C88_001518"
     CDS             complement(11157..11894)
                     /locus_tag="L7C88_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBP9558355.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11961..12530)
                     /locus_tag="L7C88_001519"
     CDS             complement(11961..12530)
                     /locus_tag="L7C88_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBP9558356.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12658..13530
                     /locus_tag="L7C88_001520"
     CDS             12658..13530
                     /locus_tag="L7C88_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBP9558357.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13872..14744
                     /locus_tag="L7C88_001521"
     CDS             13872..14744
                     /locus_tag="L7C88_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBP9558358.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14741..16699
                     /locus_tag="L7C88_001522"
     CDS             14741..16699
                     /locus_tag="L7C88_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBP9558359.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(17031..17882)
                     /locus_tag="L7C88_001523"
     CDS             complement(17031..17882)
                     /locus_tag="L7C88_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBP9558360.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            18005..18472
                     /locus_tag="L7C88_001524"
     CDS             18005..18472
                     /locus_tag="L7C88_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBP9558361.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18735..19217)
                     /locus_tag="L7C88_001525"
     CDS             complement(18735..19217)
                     /locus_tag="L7C88_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBP9558362.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(19317..20180)
                     /locus_tag="L7C88_001526"
     CDS             complement(19317..20180)
                     /locus_tag="L7C88_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBP9558363.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6196 a         4226 c         3725 g         6438 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgat cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca atcagctgac cctcggtatt agctcaaaaa acggtaaaat
     3421 atgagaagct atttttccgt tttgtttctc taatacttag gataaaacgc tgattttaca
     3481 acctctgtta aacggtgttc aatcagctgt ccttcggtat tagctcaaaa aacggcaaaa
     3541 tatgaggaac tatttttccg tttgtttctc taatactcag gacaaaacgc tgattttaca
     3601 acctcctgat aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa
     3661 aaatatgaga agctattttt gtttggctgt tcttatgact tgatgcagga cagctttttc
     3721 acaacctctg atttcttatt cttcttcatt tgtagcaaaa taattacggt gataaatgat
     3781 acaacataca ctgataagaa caatggcacc tgcaaaataa aacgcatagc tttcaccaat
     3841 atgttcacca atcacacctg caataaatgg tgctaaagct ccaccgaaaa agcggacaaa
     3901 actatagctg gacgaagcaa cgtttcgttg cagacctggt atttccatag caatcgtcgt
     3961 caacagtgta ttgataattc cttggaaaaa tcctgctaac acaatgctga tcggtacaag
     4021 gactggcata gaagttccag ctcctaataa cagcaaacaa ataatgaata agacaaatgc
     4081 tgctaaaatt gtccgataag tcgtaaactt ccgctcaaga gccggtgcaa cgaaaatcga
     4141 agcaatagcc agaagcacac cccagccaaa aaatacaaaa ccgacttcta attcagaata
     4201 gccaatcaat aaaaatggcg catacgcaag taaagtaaag aatccgaaat tatataacaa
     4261 tgcgattagt ccaactgaac gaagtttatg attgcttaac gctttgacac cttcccaaag
     4321 gcctactttt ctctttggtt tctcagtttc aggtaaaagt accgctaggg ctataaaacc
     4381 gcaaaacatc aaaaatgcta ccccaaaaaa tggataacgc catgaaccac tgcccaagac
     4441 cccaccgact agagggccaa cagccattcc gcagccaagt gctgcttcat acatcatgat
     4501 tgctttttct gtgttaccaa ctaaaatact gacgatcgtt gctaaagcag tagagacaaa
     4561 taaagcattc ccgacacccc agccggcacg taacccaatc agcattccga tattcccaga
     4621 taatccgcca agaccagcga atacaacgat gataaacaat cctgtcatca atgttttttt
     4681 caaaccgatc cgactagata agaaacctgt aaatagcatc accacaccag tgactaacat
     4741 gtaactagta aataacaggg tcgtttcagc tggcgtagcg tttaactgtg cagcaatcgt
     4801 ttttaagatt gggtctacta gacccactcc cataaaagcg atcatacagg tagctgctac
     4861 aactagcgct gaacttttcc cctttgtttc ttcatttgtt tgttcttgta tatctatttg
     4921 attctccaat atttccatcc ctttctctct attagcatca tacatgattt attttacatg
     4981 tcaatatgca catgtaaaac gtggaaactt tactgtgata taataaagaa aataagacga
     5041 gaggtaggat ttttatgaat actttagcct atatattatt atgcgtgctt ttatccaaac
     5101 cacgttctgg gtatgaattg aagcagctga tcacaatttt ttgggaagcc catcacagtc
     5161 agatctatac aacgcttgcc aagttagacc agcagggtta tgtgaccgtt ttggacaaag
     5221 acgagcactc tcaaaaaaag atctaccact tgactgatga aggacgtgct cttgtagagg
     5281 aatggatcaa agaggaaact cccgctccta cgcaaaaaga tgaatttcta gcaaaaatct
     5341 atgctttttc gacgctcgat aaaacaacag ctactggact gctattcact agagaacaac
     5401 agctgaacaa aatcatgcaa aaaaatcaaa aaaaattgaa tgacctctcg ctagacaaga
     5461 aacaagaatt tggacgttat gttgtgatcc agcgcagaat tatgctttgt cagcaggaac
     5521 tccaatggtg tcagcaagta agagaacaaa tgcagcagtt ttttgagtaa gggataaaca
     5581 gaacctttct agaaatatct attgaagagc aaattatctt caataaaaga gcaatacagt
     5641 tggaaaagaa aaagcgatcc gaacgacagg ccaaaaccta tcgttgggat cactattttt
     5701 ctagaactgc attcaagaga ctatgacaaa aagcatgcca aggccttttt tcaaataaca
     5761 gtgttccatc attcattact ttgaattgct tttagcacac ttcttgaaag cgggccaacg
     5821 atgatcaact gcaacggtaa agcggcaatc acattcattt tccaagcatt catataagca
     5881 gagaataatt gatcaggtat tccttgttcc atgatcacac cgaataaaga catacatgtc
     5941 accattccta aaaccatcaa gcatgaaata gttaagatca tttggacctt gctttctgga
     6001 tttactggta gtttaaaggc aatttttttc gccagcacac cgatgatgaa gacatccaaa
     6061 atgaaagcca ccacgaatcc aggcactaga ccaatcaaca aacttgataa atgaagatct
     6121 tgatgcagcc ataaattata cgcgctcatc cccaagacca tcaaaaaaca catcattgtt
     6181 gtaaaaatta ttccttcttt tttatttgta ggcaatctgt accactcctt taaatttgtc
     6241 acgaaaatca tcgtagcaca tttaaaaatt tctcgtaagt acttttttta ttttctgccc
     6301 ttttatttca taaacttcat cagccgtacg ctcgacaaag taagaatcat gagaagtaaa
     6361 caaaatcgtt cccggatata tttgcattag cttctctaaa gcttcgatcg ttgccatatc
     6421 aataaaatta gtcggttcat ctaacagcaa cacattactt ggcttagtaa aaagcaaagc
     6481 aatcgtcaga cgggtcgctt ctcccccact taatgtacat aacggtttcg tcaaagtttc
     6541 ctgagcaaac cctaagtgat tcagcaaact acggacaagc gattctgaaa actctgtttg
     6601 tctcatgaca aaacgaatga tggattcttc agatgtcatt tgataaccct tttgctgata
     6661 tacttgaaag cttactttcg gagagagaag gattccttct ccttgtttgc ggatatgttc
     6721 taataaggtt gtcttacctg aaccattttc accgacaatc gcgatttttt tacctaaaga
     6781 aaactgaaaa tcaccattta ccagtaatgt tctcccactt ctttccaatt ggacattttg
     6841 tcccatgatg ggatagcggc tgtggagttc aagagatttt ggtactggaa aacggatttg
     6901 tttcatctgc tgcggcttgg ttgtttctcc tattttttgg agtcttctct ctaatgtttt
     6961 cgcattcttt tggatggctt tttgtacact gtctttttgt ttagaggaag acaaccgatc
     7021 cagtctgatt tgttgctttt tctttttact ggacactttt tccaactttt ccgcttgttt
     7081 tttcttttct tggatcgatt tttccaatcg ttttttctct ttcatgatcg actctgcttc
     7141 tcgtagctga gtctttttct ccaattcctt ttgagtgaga taggcactat aattccccga
     7201 aaactctcgg atttctccgt cttttacttc ccagattttc gatgctagct catctagaaa
     7261 atagcgatca tgactaacaa aaaccagcgt accataataa taacgaagct cttcaatcag
     7321 tcgatcaata ctttttctat ctagatgggt tgttggctcg tctagaagca tcccttgttc
     7381 ataagaagaa agaagacgta tcaactcgat ctttcgttct tcccctccgc tccatttccg
     7441 ctctgaagtt tcttccagtc ttaactggaa atgactggct aattccaaat ttaggtcctt
     7501 tgcttcagcg agataggtta attgaggcag gtagttgaag gtgatctctg tttggatttt
     7561 cccatgatcg ggaaaaagtt caccggctat tagtttgagc aaagtcgatt taccgacacc
     7621 attttctcct atgatcccta tacgatcttg ctgatagaca cgaagagaat caatagatag
     7681 ttctagctgg ttgccaaagc tgacttgtag atttgttata tttactgcta aattttccat
     7741 atgttttaca ctcctatttc atgtaaaaca acaattatcg atactaaaaa agagcagaaa
     7801 aatctgtttg caaaaaaact gcatcacatc ttttcctact ctgaacgaaa taactatgac
     7861 taaatcacca aatctgtcat agctttcacc tattctactg tcgttcgaaa aaatggacat
     7921 actccatcca tgaaattgtt gtttatacat gtcttttgaa tttatttagt tgttattcaa
     7981 aagttcgaaa cgtaatttca tcgatgcagt catttttccg acctcctttt ttattaggtt
     8041 accacacacg attcaaaaaa agcaatagct actgaatagt aactgaaaac cttttattcg
     8101 aacatagtga tcttttctgg tgctaaacga acagactcgt aaccttcttc taccgctttt
     8161 cctattgata aaataataac tggaacataa cggtctttat ccaaaccaaa tgcctctgcc
     8221 aactgatctg cttcgaatcc accaattgga tttgtttcat agccatgatc acgcgcaact
     8281 aacatgaatt gcatagccgc taagctagaa tcgactttga ctacatcgtt catttcttct
     8341 cttgaaaaac tcttgtaata aggaatgatc gcagctaatt gttgatctct gacttctttt
     8401 ggcatcttcc ctgattcgta agcttggttg tagatttctt cgccatattc gtaacattgc
     8461 atatcgccaa aaatcatgac cattgcagaa gaagtatcat tttgtctcgt attgaaacgg
     8521 atcaaaggac gcaagatttc ttttgcttcc tcgctttcag cgaccacaaa gcgccatggt
     8581 ttcatattga cagaagaagg tgcagtcgtc gcttctttga tcatttccag catttcttcg
     8641 tgtgggattt tgtatgtttc atcatatacg cgaacggatc ttctaccagt cataattgtt
     8701 gaaaaatcat ttttttgttc cattattatt aacctctttc gtttctgttg ttatattgca
     8761 aagttgggta ttcaatttat ctaaaagtgt tagaaattgt ttcatttcta catcgctgaa
     8821 agccggggat agcacggaac ctgtatcttt atggtccatt tcacaatgct tgattttctt
     8881 ctgggctttt tctgttagcg ctacatacac ttcccggttg ttctgaggat ttctctgacg
     8941 cgaaacatag ccatttgctt ccaatacctt cagatgacga gtaactgctc cttgatcaat
     9001 ctgcaacttt tcttgcaaac tgctttgtag caatggattt tcttctttca gtctcatcat
     9061 gatctcgtat ctagtaagac ttataccgat attttcttca aagatctgga cgattttttg
     9121 atcggctaat ttgatttgat ataaaaggtg actaatctct tctaaagaca taatttcctc
     9181 ctttctaata attgactcgt caacgattga cttgtcaata atagaataaa aaaagaaaaa
     9241 agtcaaagaa tcagctgtgt aataaaaaaa acgctctcaa tagaaaagta tagagaaaag
     9301 aaattttttg tagaatgaac ggaaaaaatg ataaagaaag cacaacgcta aaaccaagat
     9361 tattgattct tatcaaacta tagaagatag ctcttctgca gtagataatt ttacaccgcc
     9421 aaaaatttcc gaaatcgcct tttgcaagaa tcccgtcgaa tattagaaat tggatcagta
     9481 tgcttaaaca gtaataaaaa agttatgaca agatgttgtc acaacctttt ttgagtaaac
     9541 ggtgttcaaa aacttgcatc tgcggtaata agttcaacca aacaaaaaac atgaaaatct
     9601 gtttttgttt ggctgttctt actacttgat gcagggcagc tttttcacta cctcttttta
     9661 ataaccataa aatcctattc cttcatatct ccagcccatc ggtgttagcc aatctctttc
     9721 cttagcactc aaggtatagt gatgggtacc agttttttca tttggattaa atagtcgata
     9781 aattggcttg gaaccaccag aataaaaact tagaccttca taacgccaac cgatttttgt
     9841 taaagagttg atctcagatt gtgccattgt gtaatgatgg tctccactgt aaggattgta
     9901 taaacggtag acaggttgtc cgctgtttgg tgcttgccaa gcaatccctt catattccca
     9961 gcctacagtt ggcagataat ttttttctcc ggcattcaat gtatataaat gttctcctgt
    10021 atgacggtta tacagacgat acatcggaga agttgaagtt ggtgctgtat catactgtgt
    10081 cagattatag gtttcgatta cattgttcaa tgtagaacca taattaggcg cagtggcata
    10141 acgacctgtt agccaagccg tagcatcttt gtaagagttc gtattgcttt tccatgcacc
    10201 ggaatagtag taaacgcctg gctgaaaaga agtcgtcttc aataccgtta cgttatcttg
    10261 caatgattct ttgtacgaag gatattttct aaaagcggca ttcaccgtaa tccattgccc
    10321 attcacatat tccgaagtag gcatcgtaac agattggcca ttatagcttc ctttaatccc
    10381 aaatagattg taattagggg cagaagccaa agtactgttc ccccagccac tttcaacgat
    10441 ggcttgagca atcatgactg atgcatataa gtcattggca cttgccaaac tttgtgcagt
    10501 tgaggcaata ctatcaatga acgcttgttg agaattagca gatgagcgag cataaaaagc
    10561 atagccagta tagttttcga attcagacaa atctgcttga tgggtatgtg tcaatgtttg
    10621 cccatctgtc aattggttcg tgatttcttc tgcattctct ggattgttct gagcttctgc
    10681 tgatgtactg tcttcggttt gtgtttgttc tgttgtttca gttgttggtt cttcggttga
    10741 aattgtattt tctgagacag tagctgactg caaagtactt tctgtatcgt tttcaattcc
    10801 tgtttctgaa gaactcgatg tctgagttgc gacagtttct gtcgattctt cagctagcac
    10861 tgttgtgttg gcaactgcta gatttcctaa aagaataacg ctaaataata aattctttgc
    10921 tttcatcttt tttctccttt gaattatgaa acttttccta aataacagtg taactaaaaa
    10981 agtaaaagca agtcaatgtc catatttaaa taacatttgt ttctttttaa taaatttgct
    11041 ttttctgcat aaaaagacgt aaatgaagaa tattcttctc cattcacgcc ttaaattgat
    11101 ggtcgtttga ataactattt aacaagtaat tctctctgga tattatccgt tatggattat
    11161 acttcctgtg tcgtcggacg gataatcatg ttgctgacag acatccggtc tggcgtttct
    11221 atcgcaaatg ctacagcaga agctatatct tcagatgtta atccccattc tttttgcgct
    11281 tcatgaagtt caagagcagc ctttttgtcg ctgatggttt gatataattc agtttgaaca
    11341 gctcctggag agatgatcgt agatttgatg ttattttgcc gttgctcttg acgtaatcct
    11401 tccatgattg cacggacagc aaattttgtt ccgcaataaa cggcggaatc aggataaaca
    11461 acatgtcccg ccacagaatc agttgaaatg atatgcccag atttttgttt ttccatgatt
    11521 ggaagtacgg cggaaattcc atttaacaca cccatgatgt tgatatcaag catattttgc
    11581 cattcatcac ggtgaccttc aactaatgga gcggttggca tgattcctgc attattgtac
    11641 aatacatcga ttcgaccgaa cttttccatc gctaaatcga taactgcttg gacttgtgca
    11701 aaatctctta catctgctgt ttgaatatat agctcagctt ctggtaaaga ttcttttatt
    11761 gcttttaggc gatcttctcg gcgtgcagct ataactagtt tagccccttt ttctgctaat
    11821 agcttcgttg ttgcttcacc gattccgctt gaagcgccca tgatgacaat cactttttct
    11881 gataaatcat tcattctatt ctcctcctgt tttgaaaaat ctcttgctta tactcactat
    11941 ctcttatttc atcttactgt tcaaataatc cgttcgacag gtttgacgat tttggcaggg
    12001 attcctgcaa cgatggtatt gtctgggaca tctttcgtaa cagttgcatt cgctgcaaca
    12061 atggcattct cgccaatcgt tacgcctggc agaatagttg ctcctgctcc gatccaagca
    12121 tttttcttga tgtggattgg ctttactgac aagcctcttc gttcttttgg atcggttaga
    12181 tggttcaccg tgatgaggtt gacacgagga ccaatcaata ctgaatcttc taaacagatg
    12241 ccacctaagt caacgaacat cacttgacga ttgataaaga catttttccc tatactaata
    12301 tgtttgccga aatctgtata aaaaggcagc agaacagtca ccgtatcatc tactttgtca
    12361 ctaatgatat tttctagccg tttgcggata tctgctggtt catggtaccc agtattcagc
    12421 gctgctaaag gctcttcgtt ttccgcttgg atctgatgga tcacttcaaa gagcggatcc
    12481 gttactcgaa tctctttatt gacgatttgt ttttcgatga ggcttgtcat tttgctccct
    12541 ccttttatcc ttactttata acggacggct tatgatgtct aatacttata aaacatactt
    12601 aactattcct tttaactata cttagtggta tgctttttta aaaacaggag ggaaaaaatg
    12661 gatattcgta tactgacgta ttttttagca gtagctagag aaaaaaatat cagccgagca
    12721 gcaaaatctc tgcatatcac gcaacctact ctctcaaaac aactgaaaga tttagaagaa
    12781 gaacttggtg tgacactttt cactcgaggc tcccgagaga tacagttgac ggattctggt
    12841 cgatatcttt attcaaaagg aaaagaaatc ttgtcgttgg tagaaaaaac ggcgaacaat
    12901 ttaacaaatg acgcaatcat ctctggagaa atctacattg gcggaggcga aactaaagca
    12961 atctctttca tttctgatag ccttcattcg ttgatcaagg cgcatcctga tatccagttt
    13021 catttatata gcgggaatgc agatgatatc atagacaaac tggatagcgg attacttgat
    13081 tttggactcg taatcgaacc gacaaacaaa caaaaatacc agtcatttcg actgccagcc
    13141 caagatcgtt ggggactttt gatacatcgg aatcatcctt tagcaaagca aacagtcatc
    13201 catccgcagg aactgaaaac tgttcctttg atcatttccc ggcaaacgtc agtggacagt
    13261 caactagctg aatggctagg tttcagcata gatcagttat cgatcgtcgg aacatataac
    13321 ttattgtaca atgcttcttt gatggtcgat aacgggactt ttggtgcatt agctctagat
    13381 gggatcatca atacttatgg gacggaaaaa gtattcatcc cactcgatcc gccattacaa
    13441 gcttcactga atctcatttg gaaaaaagac cagcctcttt ctcctgctgc tcgtaaattt
    13501 ttagatgtcc taacggagaa atacagttaa gtagagtttt tttccttcgc tttcagcttt
    13561 ttaacaacga ataagttaag caaaagatcc aatgattaaa taacataagt ttcttaattt
    13621 gttccttcct tttatttctg ataattccag taaattacta taattataaa aaaagaattg
    13681 acaaaacata actgtctata taaaattgat tacgttaaca ataattcgtt tcatgtgact
    13741 agatcatact aggcatgaaa aatctctgag gaacatggtt tccctaggag gtttttcgtg
    13801 tctatttttg tttggccgca atcaactggt ctagcaaacg tgaaaaccaa atcttcaaaa
    13861 agggtgcgcg catgaaaatc aaaaagatct ttaatcaaaa tgcagtattg gtagatgacg
    13921 gtggacagga aaaagtagct attggaaaag ggattggatt tgacagaaaa agaaatgatt
    13981 tgatttttga tcgtgatgtc gaacggatat ttgtcatgga accagaaggt caaatcaagt
    14041 tgcaaaattt acttaatcag attgatgaac gctttttatt tgcagcagaa acgatcattg
    14101 atcatgcgga aactgttttg atggaaaagt tgaatgaaca tgtattgatc gctttgaccg
    14161 accacattgc tttttctgcg gagaacatta ataacggtat cgtcatccgc aacaaacttt
    14221 taagagaaat cgaagtgctt tacagtgatg aattcagtat tgctcaatgg gcagtagagt
    14281 atctgacaaa agagcttggg attccatata cttatgacga agcaggatat atcgcaatcc
    14341 atattcacag cggacgaagc ggtcggaaca ataaccatcg cagtatccgt gaagtgacga
    14401 ttgtatctga catcatccat ttagtggaat cagaattgga aacagatatc cattcagaac
    14461 cattttcact gaattattca agactggtga atcatttacg actgcttcta caacgaaccc
    14521 atgcgcaaca atatgctgtt ttagacacgg aaatcgtaga aatggtcaaa cgaaaatacc
    14581 cagaaagcta taagatttct aaaaaaatcc gtgtgttgct gaccaaagaa taccagctcg
    14641 cgatcacgaa agaagaactg ggttacttgg ccatccatat cgagcgttta agaagcgcaa
    14701 tcgtacaaac aaatgttaac aatcatgagg aggaaaaaaa ttgaaagcat atctacaacg
    14761 aatgggacgt tcccttcaac ttccagttgc ggtcttacct gctgctgctt tactagtagg
    14821 gatcggaaac tggtgggcat cttatagtaa cgacattgtc gctcattttt tacaagctgg
    14881 cggtaacgca gttttaggtc aattaccttt gctgtttgcc gttgggttag cactagggat
    14941 gtcagtggac aaatcaggtg ctgctgcctt ggcaggtttg gtcgcatttg aagttccagt
    15001 aaatgtttta aaaactgatt cagtagctac tttattgaat atcaaaccag aatcagttga
    15061 tccatctttt gctcagatca gtaacgtatt tattggtatt attgccggat tgattgcggc
    15121 agctctttat aatcgtttcc acgaagcaaa attaccgatg gctttatctt tctttagcgg
    15181 caagcgtcta gtgccaatct tggctgcctt tgtcatgttg ctgatcagtg cagtgctact
    15241 gctcgtatgg cctccggttt actctgcttt agtttctttt gctaaattca ttttgagttt
    15301 aggctggggt ggtgcaggtc tttatggctt cttcaaccgt ttactgatcc ctacaggatt
    15361 gcatcaagca atgaactccg tgttctggtt tgacgtagca ggaatcaatg atattggtaa
    15421 atttttggct tctgaaggaa caaaaggcgt aacaggaatg tatcaagctg gatttttccc
    15481 aatcatgatg ttcgggcttc cagcaggagc atatgctatt tacagaaatg cacgtccaga
    15541 aaacaaagca aaaacagctt ccttgatgtt agcagcagct tttgcttcat tctttactgg
    15601 tgtaacagaa ccacttgaat tctcatttat gttcgttgct tggccattat atgtcttgca
    15661 tgcaattttc actgggattt ctttagcagt gagtgcattc ttccattgga cagcaggatt
    15721 tgcctttagt gccggatttg tcgattactt cctatctttg aaaaatccga ttgcgaatca
    15781 gccattgatg ttgatcgtcc aaggattagt aacagcagtg atttactact ttggctttaa
    15841 ctttgctatc aaaaaattcc atctgatgac tcctggccgc gaggaagcag atctttcaga
    15901 tgacgatact gcaacgacta attcagacaa taaatatgcg gcacaagcaa gcaaaatcta
    15961 cgctgcatta ggcggagccg acaatgtaac ttcgatcgat aactgtacta cacgccttcg
    16021 tttgcaagtc aaagatacag gcctgatcga tcaaaataaa atcaaagcca ctggcgtacc
    16081 tggtatgaag atcatcgacg gaaaaaatgc gcaagtcatc gtaggtacag aagtacaatt
    16141 cgttgcagat gagatggcaa aactacatgg tggtgctgca acacgacctg cacaaacaaa
    16201 caccgtggtt aaaacagaaa catttgccgg tggaacgatc gaacaagata tttacgctat
    16261 cgcaaatggg aaactgattc caatcactga agtttcagat gatgtattcg cggaaaaaat
    16321 gatgggtgac ggctatgctg tattaccaga aaatggagaa atcttctctc caatcgctgg
    16381 tacgatcaca aacattttcc caacgaaaca tgctgtcgga atccaaacag atgctggtat
    16441 cgaagtcttg cttcatatgg gcatcaacac tgttgactta aaaggcgaac cattcacttt
    16501 atatgtaaaa gaaggtcaaa aagtcgcaag aggtcaattg attgctttag ttgatcttgc
    16561 cgctattcaa tctgcaggca aaaacacgga tatggtcgtt gtattcacaa atggcgacaa
    16621 agtccaaagc ttagaaatcg aacccgcacg tgatgtaaaa gcaaatgata aaatcggctc
    16681 tgtttccaac aaagcctgag ccatcgtctt ccccagactt ttttatcgat aaacaaacag
    16741 gagctgagac aaaaatcttg tctcagctcc tttttccgaa taaaaacggc gttctcctgc
    16801 caactccgcg gtaataagtc cagccaaacg taacatatga agagctattt tttatttgac
    16861 tcttcttatt acttgatgca gaacagcttt tttacaacct ctgataaacg gtgttcaaaa
    16921 accagtttat cggtatgaag tcaaatttat gcaaaaatgt ggaaagccat tttcacaaaa
    16981 tttttcttca tactcaaaac taatcggctt tttcacaacc tctttataca ttattcctga
    17041 tccaatattt cttttaatgc tgcttcaaga gaagttaatg gttttcccaa tactttttct
    17101 aaatcatcag aggaaatagc taactgatcc tttttaatat catgttggat cgctaaaaac
    17161 atgtcagctg cttcttgagg gaatccggct tcttttagat tttcgacaaa cgctgcatca
    17221 cttgcttcaa taatttctaa ctttttacct gtcgcacgct ctaatgcctt ggctaattct
    17281 tcatagtcag ttagattgcc ggataattct aagatttctg gagagtcact ttctactagt
    17341 acttttgctg cagcttctgc atattcacgt ttcaatgccc aacctgtttt tccatttcct
    17401 gcagcataaa cgaattgacc agtttttaaa gcctgcccaa tgataggtaa ttcattctct
    17461 acataccaat tattccgtaa aaatgtatgg gaaatacctg aatccttaat cattttttca
    17521 gtgaattggt gatctggcgc taatacactg atcgagtgat cggcatctgc aaaacttgta
    17581 taagcgatat aagatacccc agctgcttgt gctgccttca ctacattctt atgttcggct
    17641 tgacgatttc ctggaacgcc agagacaaaa agcaatcgat ctattccttt caacgcttct
    17701 ttcattgagt ctaaatcatc ataatcacca atacgtatat taaatccagc ttctttcagt
    17761 gcttctcctt tttcttcact acgtactagt acatagattt cattttgtgg aaccatcttt
    17821 tttaagaatt ccagcgcata accaccaaaa cctccagttg ctcctgttac taaataatgc
    17881 atatttgcca ctccctattc tttttatttg ttaagattta cagctgtaca tttataaatt
    17941 acacctttat cataaagagt gtggtaagat aagtcaagca aaaaaaatga aaggatgaca
    18001 actgatgaag tattctctgc aatttagtga tgcaatccat gtacttgcct atattgaaat
    18061 gtttcaagat acccgatcac tttctagtga gatgattgcc agtagtatcg aaacaaatgc
    18121 agcaaatgta cgtaaaatca tgagtcagct caaaaaatcc ggtttgatct ttacaaaaac
    18181 cggaaaaccg cagccttccc ttgccaaaag tccagatcag atttctttac tagatgtcta
    18241 tcgcagcatc gaaggtaata cacagcttat ccaagtcgat ccaaaaacaa atccaaattg
    18301 cgtcgttggt gcgaatatcc aagaagcttt agaagaaagc tacgctcggc tgcagaaaaa
    18361 ggcagaagaa gaaatggcta agatcacact tgatagtctg atacataaaa tagccgtttt
    18421 ggaaaaagaa aaaagaccag aaaacacagg cctcgtagag agatttttat aattctctct
    18481 actgtgcctg catttttctg atcggaatcg tctacataaa ttcttttatt ctccggggga
    18541 caaaagcctt gtcatgcccc tttttcctct ctaatgctca ggtcaaagcg ctgaagtcat
    18601 gacgtcttga taaacggtgt tcaagtagct gaccctcggc attagttctg aaaaatgcaa
    18661 aatatggaaa gctatttccc atttttcctc tctaatgctc aggtcaaagc gctactttca
    18721 cgacctctat attatcatgg tttattgact accggtatcc agatttctcc catatatttc
    18781 ccgttggtaa ctcccatttc gactacagca tttggacccc caacataggc gtaatcttct
    18841 acttctctta aaacatgccc aaaggccgta ttcgtcaaat catttcttaa ttcttcaggc
    18901 gattctgcta aagcgattac aacaagatac gttccttttg ggaatgggat gattcgggta
    18961 gtgtttggaa catcctgact cgtttgaaca ccgacatagt acatcatttt cccgttatag
    19021 ggttcgttga ctgtaaagaa ataatgattt tcagcagctt gtttcaatgc atctattgtt
    19081 ccattaccga taactttttg ctcaaatgct tgtttctctg cagccaaacc gacaaaatcc
    19141 gtattgctac tcttcaattc cacaccaata cccgtcaccg taaaatctgg tttttcttcg
    19201 atcctatact ttgccatttc tcccaccctt tctattatat taagttcatc ttacataaaa
    19261 ttaaagggaa atgacacgat tacgctcttt tttctaggga tatttttatt ttttaactat
    19321 ttttttgctt tcactgcaat ccaaatctca ctgtaaacat tactgaaatc ctctccccat
    19381 tttgtaaaag agatctcggg agcttcgact aactcataat ctgaagaagg aagccattct
    19441 gcatagattt tcccccaagt atcttgtaaa gtttggggaa atggcccttt attaggaaaa
    19501 atggcccaag tgtgttcttc tatagcaagc atttctaaat cagcgtacgg attttctttt
    19561 gtcgtagcaa agccaatcat gtgcatcaaa ctgccctttt cttccaagcg ggctccatca
    19621 aatccataag aaacgttgat tacttgattt ggatataaat ctcctaactt atgcatctct
    19681 tccctttgag tctccgtgat cgtctgcgct aacttttgta tttcttgatt gactccttca
    19741 aatttgacag gaactttttt cgccacacct gccacataaa actgttcttt cttttcgata
    19801 cgaaattcca tcgattttcc tcctctgaca tcaataaaaa atgtcaagcg tggaaaagat
    19861 ttttgtatgc cgtatctgct gatttctgaa ggcagatatc ctgaccaatc acgaaaagct
    19921 cttgaaaaac cttcgactgt ttcatatcca tatctaaacg ccgtttctgt cactcttgat
    19981 ccatctagga gatcgcgatt agccaaagcc aatctacggt ttttgatata gtccattagc
    20041 gacatccctg caataaacgt aaagatgcgt tttaattgat attcagagat tcctgtattt
    20101 tcggctatta ttttatagga aagtccttct gtcaaatgtt cttcgatgta atcgatcaat
    20161 tggttcagat ctttaagcat atttatcttc ctccttgctt gcctttttat catattatca
    20221 aagaaagtca attacttgat gaatcaggaa ccaatttagt cagatgtaga aaatgttgta
    20281 tggatctaaa gaaaattctc aagcagcgtt tcgtaacgga taattggtat tatctgccta
    20341 tctatgtttt acctttagaa aaataaattt tggggaagac acattctaag taaacaaagc
    20401 ggtaaaaata tcttttattc ccttagttaa tccgcttact acctactgta caaagcaaat
    20461 tgttgttcaa actgctgatc agaacgctgc ttggattttt ctttgcgata catcatacct
    20521 cttttatcaa ttggaacaat tatttatttc taacaaaatc acttcatttt tgtcagataa
    20581 ataaa
//
LOCUS       DAFTHM010000043        20484 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFTHM010000043 DAFTHM010000000
VERSION     DAFTHM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.043"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            3..551
                     /gene="hslV"
                     /locus_tag="L7C88_001527"
     CDS             3..551
                     /gene="hslV"
                     /locus_tag="L7C88_001527"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBP9558364.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            565..1965
                     /gene="hslU"
                     /locus_tag="L7C88_001528"
     CDS             565..1965
                     /gene="hslU"
                     /locus_tag="L7C88_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBP9558365.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            1983..2774
                     /gene="codY"
                     /locus_tag="L7C88_001529"
     CDS             1983..2774
                     /gene="codY"
                     /locus_tag="L7C88_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBP9558366.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            2856..3731
                     /locus_tag="L7C88_001530"
     CDS             2856..3731
                     /locus_tag="L7C88_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBP9558367.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(3863..4501)
                     /gene="plsY"
                     /locus_tag="L7C88_001531"
     CDS             complement(3863..4501)
                     /gene="plsY"
                     /locus_tag="L7C88_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBP9558368.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            4628..5062
                     /locus_tag="L7C88_001532"
     CDS             4628..5062
                     /locus_tag="L7C88_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBP9558369.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            5228..7273
                     /gene="parE"
                     /locus_tag="L7C88_001533"
     CDS             5228..7273
                     /gene="parE"
                     /locus_tag="L7C88_001533"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBP9558370.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            7285..9735
                     /gene="parC"
                     /locus_tag="L7C88_001534"
     CDS             7285..9735
                     /gene="parC"
                     /locus_tag="L7C88_001534"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBP9558371.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            10012..12243
                     /gene="pflB"
                     /locus_tag="L7C88_001535"
     CDS             10012..12243
                     /gene="pflB"
                     /locus_tag="L7C88_001535"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBP9558372.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            12487..13248
                     /gene="pflA"
                     /locus_tag="L7C88_001536"
     CDS             12487..13248
                     /gene="pflA"
                     /locus_tag="L7C88_001536"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBP9558373.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            13333..14259
                     /locus_tag="L7C88_001537"
     CDS             13333..14259
                     /locus_tag="L7C88_001537"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBP9558374.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            14441..15334
                     /locus_tag="L7C88_001538"
     CDS             14441..15334
                     /locus_tag="L7C88_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBP9558375.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            15468..15593
                     /locus_tag="L7C88_001539"
     CDS             15468..15593
                     /locus_tag="L7C88_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9558376.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(15727..16359)
                     /locus_tag="L7C88_001540"
     CDS             complement(15727..16359)
                     /locus_tag="L7C88_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558377.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(16507..17049)
                     /locus_tag="L7C88_001541"
     CDS             complement(16507..17049)
                     /locus_tag="L7C88_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBP9558378.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            17184..17573
                     /locus_tag="L7C88_001542"
     CDS             17184..17573
                     /locus_tag="L7C88_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558379.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            17577..18341
                     /locus_tag="L7C88_001543"
     CDS             17577..18341
                     /locus_tag="L7C88_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBP9558380.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            18470..19417
                     /locus_tag="L7C88_001544"
     CDS             18470..19417
                     /locus_tag="L7C88_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9558381.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            19547..20287
                     /locus_tag="L7C88_001545"
     CDS             19547..20287
                     /locus_tag="L7C88_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558382.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT         7192 a         3481 c         4316 g         5495 t
ORIGIN      
        1 acatggtcga atcaccattt cattcaacca ctatctgtgc cgtcgaaaaa gacgggaaat
       61 ttgctatggc tggagatggc caagtaacaa tgggtgaatc tgttgtcatg aaaggcactg
      121 caaagaaagt acgacgtatc tacaatggag aagttgttgt aggtttcgcc ggaagtgttg
      181 cagatgcgtt tactttagaa gaaaaatttg aaggcaaact aaacgaatat aacgggaatc
      241 tacaacgcgc agctgtcgaa ttagctcaag aatggcggac acagcaatct atgcaaaaac
      301 ttgaagcgat gctgatcgta atgaatgata aagaaatgct tcttgtttca ggtacaggag
      361 aagttatcac accagatgat ggtatcttag ctatcggatc aggagggaat tttgcgttgg
      421 ctgcagcccg agcaatgaaa aactatgctc aaaacgacat gagtgcgaaa gaaattgcag
      481 aaaatgcgtt aaatattgcc gcagatatct gtatctttac taatcataat attatcgtag
      541 aagaactgta agaggtgagt agatatgtat gaattaaaac aaacaccaag acaaatcgta
      601 agtgaattag atgaatatat cgtaggacag cacgcagcaa aaaaatctgt tgccgttgct
      661 ttgcgtaacc gctatcgccg tttgcagtta gatgaaaaaa tgcaacaaga tattacacca
      721 aaaaatatgc tgatgatcgg acctacaggg gtcggtaaaa cagaaatcgc acgacgtttg
      781 gcaaaaatcg tcaatgcacc atttgtcaaa gtcgaagcaa caaaatttac tgaagtcggt
      841 tatgtcggaa gagatgtaga atcaatggtt cgggatttag tagaaaatgc gatccaaatc
      901 gtagaaaaag agcagtacag ccgtgtatac acaagtgcta aaaaaaatgc agaaaaacgt
      961 ttggtaaaaa tcttggtacc tggtatcaaa aaagaacaga aacaatccac taatcaattt
     1021 gaacaaatga tgaatctttt taatgctagt cagcaaaata ccgctgaacc gcaagaagaa
     1081 gtgacagaag atattcgaat caatcgccgt acagtcttgg aacaactaca aaagggttta
     1141 ctggatagtc gtgaagtaac cattgaagtt gaagaccaaa agaaacctgc accaatgatg
     1201 aacaatggat tggagcaaat ggggatcgac ctaaatgaaa ctctaggtgc tttgacaccg
     1261 aagaaaaaag tggaacggac ggtaacagtc aaagaagctt tagagttatt gatcaaggaa
     1321 gaatcagcaa aattagtcaa ggatgctgat atccatagtg aggcaatcaa attagcggaa
     1381 gaaagtggaa ttatttttat cgatgaaatc gataagatca cttctaaatc acagcaatct
     1441 ggagaagtat ccagagaagg cgtccaaaga gacatattgc caattgtcga aggttcacaa
     1501 gtaaacacaa aatacgggat catccaaaca gatcacgtcc tattcattgc ttcaggagct
     1561 ttccatttgt ctaaaccaag tgatctaatt ccagaacttc aaggacgctt cccgatacgg
     1621 gtagaattag atgatttgac agctgaagat tttgtgaaga ttctgaccga accaaataat
     1681 gctttagtaa aacaatacgt cgcgttgatc ggtacagaaa atgtgtcagt tacgtttaca
     1741 aaagaagcaa ttgaacggat cgctcaaatc gctttcgatg tcaaccgtga cacagataat
     1801 atcggcgcac gcagactgca taccattttg gaaaaactac tagaagatct attatttgaa
     1861 gcaccagata tgcaaatggg agaaataacg atcacagaag catatgtgga tgacaaactt
     1921 ggctcaattg cggcaaatga agatttaagt cgctatattt tataaaaaat cggaggacga
     1981 caatgacaga cttgctaacg aaaacccgca agataaacac acttttgcag caaaagaata
     2041 cttttgacat gcaagcagat ttgccttacg ataaaatggc tgtcacacta ggtggtattc
     2101 ttgacagcaa cacctatatc ataggaagtg acggagtatt actaggttat aatgaacgtc
     2161 acgatgtgaa caatgaacga atcaaaacaa tgtttgttga gaaacaattt cctgaatctt
     2221 atactgatac agtggcacag ttgatgaaaa ctgaagctaa tatcccaatt actagtgata
     2281 ttactgcatt tccggtagag tcaagagaga aatatccatt tggtctgacg actgtcgttc
     2341 cgatctttgg agctggcgaa cgtttgggta cgattatctt atctcgtatg gaacaatcgt
     2401 ttgcagatga cgatctagtc ttagcagaat atggagctac ggttgtcggt atgcagatcc
     2461 tttatcagaa gtctcgaagc atcgaagcag atgtacggag tgcaacggct gtccaaatgg
     2521 caatcaacac attatcttat agcgaattga aggctgtaca agctatcttt gaagcattgg
     2581 atggagatga aggtcgtctg actgcttcta atattgccga tagtatcggc atcactcgtt
     2641 ctgtgatcgt caatgcttta cgaaaattgg aatcagctgg aatcattgaa tctcgttcgt
     2701 taggcatgaa gggaacttat ttaaaagtat tgaattcccg ttttaaagac gagttagcaa
     2761 aacacagtta ttagaagtaa ggggactggg gcagatagaa atgtttgttc cagccttccc
     2821 attttaaaaa gtaagtcgaa gttggaggaa tggcaatgac tgttattatt caaaatgacc
     2881 agctgatcgc cgaaatcgct gaacacggtg cggaattgat cagtctgaaa tcaaaagaac
     2941 atggtttaga gtatatctgg caaggtgatc cagcgtattg gggcagacat gcaccggttt
     3001 tattcccttt tgttggacgt ttaaaagatg atcagtatgt ttatcaaggg aaaacatatc
     3061 aaatggggca acacggattt gctcgggata tggattttga agtcattgaa catggacaag
     3121 aaatggctag tttcatctta aggagtacgc cggagacatt agaaaagtat ccatttgatt
     3181 ttgaattagt gatcagctat gaattaggag gagacggcat cacggttcat tatcaagtgg
     3241 caaataccgg tgaaaaagaa atgttctttt ctatcggtgg acatcctgct ttcaatgtac
     3301 ctcttgaaga aggattgtca tttgaagatt tctatctggc attttctcca ttgaaatcaa
     3361 gattacgcct accattgaaa ggcccattca tcgatatgga tcaaaagacg ttaggtcaga
     3421 caaatacgaa tctggctttg aatcgtgaac tttttgagca agatgccttg gtttttgaaa
     3481 caaggggtct aaatgcgtac gccattcgaa gtgaaaaatc ttcccatagc gtaactttaa
     3541 gctataaaga tatgccttat gtagggatct ggtctcctta tccaaaagaa gcgcctttcg
     3601 tttgtatcga accgtggtgc ggaatcgctg acacggtgaa cagtagtgga aacttgatgg
     3661 aaaaagtagg gatcaatcaa ctaggtgccc atgaaatctt caagacaaaa tattccatca
     3721 cagtgaagta agaggttgtg accgagaagt tagcagggaa caccgtttac caaggtgtgt
     3781 aaaaaagcta tcctgtaagt aataagggag tgtgacatcg atttgtcaca ctcccgtttt
     3841 atctctttgg aatgaaaaag tatcaggatt ttttcttgct gctattcaaa ccaaacggga
     3901 ttcgactttc agtatggttt ctgatacgct tgatattgtc tttatgccga taaaagataa
     3961 aggaagaaac taaaaaggca atgatcgtca gtaaccaatt gggcttagcc aaaatcacag
     4021 gagctacata aggaaggacg atcgtagata aagtgatcaa tactgcactg atcatactgc
     4081 tcaaactcac catacttgta caaaataaac taacgataaa gatgatacaa gaataaacaa
     4141 aaaatacagg attaaatcct aaaagcattc ctgcacttgt cgcaacagct tttcctcctt
     4201 tgaacccagc aaaaatcgga aatgtatggc caagaatggc gcatacccca aaccaaagag
     4261 ggttaatccc agaaaggtgg aagatcatcg gcaaacaagt agccaatgta ccttttaaaa
     4321 tatccataag caggacaaca atcccggctg ttttgcctaa tacacgaaat gtattggtcg
     4381 ttccagtatt accgctcccg tgttgtcgga tatctttttt gaaaaacaat ttgccaatcc
     4441 agacaccgga aggaatagaa cctaaaagat atgctaaaat aagtaataag atcaatttca
     4501 ttttttaccc tctttcaagt tgaaaactat cctttatttt agcatgaata ggtaacagga
     4561 acaattgaaa aaatgaaaga tacaagtata atagatggaa taaaaagaaa agcaaggggt
     4621 ggcagaaatg tctgtaaaaa atccaacaca agaaacgatt ttcaactatt tggaagaagc
     4681 aaaaaatatt gccgtcgtag gcttgagcaa taaaccagaa cgaacaagtt acatggttgc
     4741 acaggtattg caagacaatg gatataaaat cataccagta aatccattat tggctggtga
     4801 agaaattcta ggcgagaaag tctatgcgaa tttgacagaa atcgatgatc caatcgatat
     4861 cgtagatgta tttagacgga gtgaattttt acctgaaata gcaggtgatt ttttgaaaac
     4921 tgatgctaaa gtgttctggg cacaattagg gattgaaaac aaagaagcag ctgagatgct
     4981 aagaaaagca ggacgtacag atatcgtaat ggatcgttgt attaagattg aacttggtaa
     5041 gttgaaagaa aaccaaaaat aaaaatgacc acaaagaaga gatgatcgat agaggggaat
     5101 gtcgaaaaag cggttaggag ataattaaaa ttgatttctc gtctaccctc ttttttttca
     5161 cgaccttttc tagtatgata atcgtggtgc ggttttgccg caaagtatta ttgaaggagc
     5221 gtttgccttg gcaaaaaaag taaacaacga atacaatgac tcgtccatcc aagtattgga
     5281 aggattagag gcagttagaa aaagaccagg gatgtacatt ggatccactg acagccgagg
     5341 cttgcatcat ttagtctatg aaatcgtcga taatgcagtt gacgaagcat tatcaggtta
     5401 tggcagtgag attgatgtga ccatccatga agacaatagt ataactgttg cagatagcgg
     5461 acgtgggatg cctgtaggaa tgcatgcttc cggaatacca acagttgaag tgatttttac
     5521 tgtgctgcat gctggcggaa agtttggtca aggagggtac aaaacttctg gtggactgca
     5581 cggtgtagga gccagtgtgg taaatgcctt atcgaaatgg ctaattgtaa cgatcgttag
     5641 agatggcgta gagtatcagc agaaatttaa aaacggcggt aaacctgacg gtactttgaa
     5701 aaagatagga aaaacaaaaa aagcaaacgg gacgactgtc cattttttac cagatgatac
     5761 aatattcagt acaacgaaat tttcatatga aattttagcc gaacggttaa gagaatctgc
     5821 ctttcttcta aaaggcgtta aaatctctct ttctgatctt cgtggagaag aaccagtcaa
     5881 ggaaattttt cattacgaag aaggaatcaa agaatttgtt gattatctga atgaagaaaa
     5941 agatacattg acaccagttg tttatttttc aggagaaaaa gaaggtatcg aagtagaggt
     6001 cgcttatcaa tacaatgacg gttattcaga aaatgtttta tcttttgtca ataacgttcg
     6061 gacaaaagat gggggaaccc atgaagctgg tatgaaagcg gcgatgacga aatcttataa
     6121 tgaatatgcg agaaaagttg gtttgctgaa agaacgggac aagaatctgg aaggtagtga
     6181 tttcagagaa gggttagctg ctgtactttc tatccgtgta cctgaaaatc ttctgcaatt
     6241 tgaagggcaa acaaaagaaa aacttggtac gccagttgct cgtaccgtag tagataacgt
     6301 catcagtgaa caaatgggct tttatttgca ggaaaatagc gaaatgagcc agatgttggt
     6361 ccgtaaagca atcaaagcca gagaagcgag agaagcagca cgtaaagcca gagaagaaag
     6421 ccgaaatggg aagaagcgta aaaaaggcga atctcttctt tcaggaaaat tgacacccgc
     6481 acaatcccga aaccctaaga aaaatgaatt gtatttagtc gaaggggatt ctgctggcgg
     6541 atctgctaaa caaggaagag acagaaagtt ccaagcaatt ctacctttac gaggaaaagt
     6601 catcaatacc gaaaaagcta aaatgcaaga tatcttgaaa aatgaagaaa tcaatacgat
     6661 gatctatacg attggtgcag gagtcggtcc tgagttttct atcgaagact gtaattacga
     6721 caaagtaatc atcatgaccg atgcggatac agacggcgcc catattcaag tattactgct
     6781 tactttcttt tatcgttata tgaaaccgct gattgaagct gggaaagtat atatcgcgtt
     6841 accgccttta tataaagtat ccaaaggaca aggaaagaag caagtcattg aatatgcgtg
     6901 gacagatgac gaattggcag caatgattaa aaaagtcggc aaaggatata tgctgcagcg
     6961 atataaagga cttggagaga tgaatgcgga acaattgtgg gaaacaacga tggatccgac
     7021 ttcccgtacg ttgatccgcg tccgtatcga tgatgctgcg caagctgaac gtcgagtaac
     7081 cacactgatg ggtgacaaag tagaacctcg aagaaaatgg atcgaaaatc acgtgcaatt
     7141 tacgctcgaa gaagatggca gtatcttaga taaaaaagag gatactgaaa tctctccttc
     7201 agtttctaat gatttattag atgaagaacg agcagataaa aatgaaaaca atcagttatt
     7261 tgaagtagaa taggaggtca cctgatggaa aatcgacaag aagtacaaga attaacttta
     7321 gaagaagtga tgggtgaccg cttcggacgt tattccaaat atattatcca agaacgtgca
     7381 ctgcctgata tccgtgatgg attgaagcca gtgcaacgcc ggatattatt tgccatgaac
     7441 aaagatggca atacgtatga caaaggattc cgtaaatcag caaaatctgt cggaaatatc
     7501 atggggaatt atcatcctca tggtgacatc agtatttatg aagcgatggt ccgcatgagc
     7561 caagactgga agttgcggga agtactgatc gaaatgcacg ggaataacgg gagtatggac
     7621 ggtgatccac ctgctgcgat gcgttatact gaagccagat tatccaagtt aagtggagag
     7681 atgctagcag atatcgagaa agaaacagtc gatctcgtgt ggaattttga tgatacagaa
     7741 aaagaaccaa cagtccttcc agctcgatac ccaaaccttc tcgtcaatgg atcgacaggt
     7801 atatctgctg gatatgcaac agaaatcccg actcataact tagctgaagt gatcgatggc
     7861 acaatctata tgatcgatca tccacaagcg agccttgaaa aattgatgga atatattcct
     7921 ggacctgact ttccaacagg agggatcttg caaggaaaag atgaaatcaa aaaagcttat
     7981 gaaacaggac gaggaaaagt tattcttcgt tcgaaaacaa agatagaggc aatgaagggt
     8041 aataaacagc aaatcgtgat cacagaaatc ccatatgaag taaataaagc gaccttggtg
     8101 aaaaaaatgg atgagatccg tttgaataag aaaatcgatg gaatagctga agtacgagat
     8161 gaaagtgata gaacaggtct gcaaattgtc gtcgaattga aaaaagacgc caatgctcaa
     8221 ggaattttga attatttgtt caaaaacact gagctacaga tcaattacaa tttcaatatg
     8281 gtcgctatcg accatatgac tccgcatcaa gttggactga aagacatttt aagaagttat
     8341 atcgagcatc gaaagcaagt cataacaaaa cgtagtcaat tcgatttagc caaagctcaa
     8401 aaaagacagc atatcgtaga aggattgatg aaagctttat cgattctgga tgaagtaatc
     8461 gcaacgattc gtgaaagtaa agacaaaaaa gacgccaaaa agaatttagt cgacgtcttt
     8521 caatttacag aagaacaagc agaagcaatt gtcacattgc aattataccg tttgacgaac
     8581 acggatatca cagagcttca aaaggaatcc gaaagcttga ttgcgcaaat cacagagttg
     8641 aataaaatcc tttcaaatga caaagagctt ttctctgtta tgaaaaaaga attgcgagaa
     8701 gtgaaaaaaa attattcttc cgctcgtcta acgacaatcg aagacgaaat cgaagaaatc
     8761 aaaattgata cgcaagtctt agtggcacaa gaagacgtaa ttgtcagtgt gacgcgagaa
     8821 ggctatgtga agcgaacaag ccttcgttct tatagtgctt ccaaaccaga agaaatcggg
     8881 atgcgagaag gcgactactt gctatactca ggtgaattga gtacattgga ccatgttctt
     8941 ctgatcacaa ataaagcaaa tgtgatctac cgccctgtcc atgaactacc cgatttgaaa
     9001 tggaaagatg ctggtgagca catttctcaa acaatctcca atctgtctgt agacgaatcg
     9061 attttagctg ttttcccata tcaaaaaatt caagcagaga aaacatttgt attcatcagc
     9121 aagaatggat tgatcaagca aacacgaatg acagagttcg aaccatggcg cacctataag
     9181 agccgtccgc tcagctgtat gaagctaaag gcggaagaag atgaactgat tgctgtgtat
     9241 ctgaaagaag atcagccagg cttagatgtt ttcttagtaa cgcatcaagg aatgggtttg
     9301 cgctatcctt taacagatgt tcccgttgtt ggagcaaagg cagctggagt gaagtctatg
     9361 aatttgaaag atggagatag gattatcaac gggctgcttg tgttagcaga aggtgatacg
     9421 ccgatcgtaa tcgttactca gcgaggagct gttaaacgca tgcttgctca agaaatcagc
     9481 caaacttcac gtgcgaagcg gggagtgacg gtcatgcgtg agctgaaaaa aaatccgcac
     9541 cgtattatct atatgtcgga aggaagatca aaagaaataa ccttgatgaa tcaaaaaggg
     9601 cagcagttaa cgattgaccc aactgatttc cctataggtg atcgaacatc gaatggatca
     9661 tttgcgatgg atgagaaaaa aggtggagaa gtcatcgaag ttatcgatgc tcctgagatt
     9721 ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga cgccatctgt attaatacag
     9781 gtggcgtctc tttttcattc atttttaata aatccttata cgtttgcaaa aaaagatgaa
     9841 agtgttcaca atgcttaaat gttggtatgt caacgttgat ttaaatatat gtaaataaaa
     9901 cataaaaatt gttaaataaa aaacaagaaa acccttgcaa agatagggtg ctgtgttata
     9961 ctaatcacgt aaaaactgtt acataaaaca gaaatttagg aggtccatac aatggagcaa
    10021 tggaatggat ttaaaggtac caaatggaaa gaaggcgtag acactagaga ctttattcaa
    10081 aataactaca ctgaatatcg cggtgatgac agctttttgg aaggcccaac agaagcaaca
    10141 gaaaaattat gggatgaatt gcaaaagtta aatgatatcc aattcgagcg taacggtgtc
    10201 tatgatatgg acacagaaat cgtatcaact attacttcac acgatgcagg ctatttggat
    10261 aaagatttgg aaaaaatcgt cggtctacag acagacaaac ctttgaaaca agcattcatg
    10321 ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa gcaatggcta tacaccaaac
    10381 gatgaattga cacatatttt cactgactgg cgcaaaacac ataatcaagg tgtatttgac
    10441 gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa tcattacagg gcttccagac
    10501 gcttacggtc gcggacgtat catcggtgac tatcgtcgtg tggcattgta tggaatcgac
    10561 tatttgatgg aacaaaagaa aaaagatcat gatatgactg gttatcatac aatgagtgaa
    10621 gaagtgattc gtttacgtga agaaatcact gaacaatatc gtgcattagc gcaaatgaaa
    10681 gaaatggctg cgaaatatgg ctatgatatt tctaaaccag ctgcaaatgc aaaagaagct
    10741 gtccaatggc tatacttcgg atatttagca gcaatcaaat cacaaaatgg tgctgcgatg
    10801 tcaatcggac gtatctcagc attccttgat atctatatcc aacgtgattt ggataatgga
    10861 gtaatcacag aaaaagaagc acaagaattg atcgaccact tagtaatgaa attacgtatg
    10921 gtcaaattcg cgcgtacacc tgaatataac caattattct caggattccc tatctgggct
    10981 actttatcca ttgcaggtat gggattagat ggtcgttcat tagttacaaa gaatgatttc
    11041 cgtctgcttc atacattaac aaatatggga ccttcaccag aaccaaactt gactgttttg
    11101 tattctgaac accttccaga aggattcaga acatatgcta gcagaatcgc tatcgaaagt
    11161 tcttcgattc aattcgaaaa tgataatcag cttcgtgaac aatggggttc tgatgattgt
    11221 gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag acatgcaatt ctttggcgct
    11281 cgtgctaact tggctaaaac actattatat gccatcaatg gcggagtcga tgaagtgact
    11341 ggcgcccaag ttggaccaga atatcgtcca atcacatcag aaatactaga ctttgaagaa
    11401 gtgaaacata acttcatgaa tatgatggat tggttagcag aactatatgt caatacgttg
    11461 aacatcattc attatatgca tgataaatat tcttatgaag cagctcagct ggctttgatg
    11521 gattctgact tgcaacgcac atttgctaca ggtattgctg ggatctctca tgcggcagac
    11581 agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc gtaatgaaaa aggaatagca
    11641 gttgattttg aagtggatgg cgacttccct aaatacggaa atgatgatga ccgtgcagat
    11701 gaattagttt catggatctt ggaatacttc atgggacaaa tcaaacgtca taaaacttac
    11761 cgcaactcaa aaccaacaac ttcattattg acgattactt caaatgttgt ttacggtaaa
    11821 aatacaggaa atactcctga tggccgtgaa gctggaaaac cacttgcgcc aggagcaaat
    11881 ccaagttaca atgcggaaca aagtgggtta ttagctagcc tgaactcaac agctaaaatg
    11941 aattacggct gtgcattgga tggaatttca aatacccaaa caatcaatcc ttcaggtctt
    12001 ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg tcttagatgg atacttctca
    12061 aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg atttattgcg tgatgcaatg
    12121 gaaaatccaa tgaaatatcc gaacttgacg atccgggtat ctggttatgc agttaaattc
    12181 cgtgacttga caagagaaca acaattagat gtcttgatga gaacttcaca cgacagaatg
    12241 taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa aggacgttga atagccatcg
    12301 catcaaaatc gaataatcag tatgcttatt tgaaagaaac gatttacagg ggcaggactt
    12361 gtatgttccg tccctgtaaa ttttacacat aacgaagcgg caattgcgaa aaattttgtt
    12421 cagaaagctt cgcttcgaca gctaacttgt acttaaaatg aaatcaaaga aaagatgtga
    12481 acttaaatgg aagaaaaaac aatcggctat gttcattcta tcgaaacttt cggttcagta
    12541 gacggacctg gactgcgctt tgtcgtgttt atgcaaggat gccgcatgcg ttgccaattt
    12601 tgtcacaatc cagatacttg gaatattggc ggagggaaag aatacacagc agatgaactt
    12661 ttagataaag cagaacgctt cagaccttac tggggagata aaggtggtat tactgttagt
    12721 ggtggagaac ctctattgca gatcgatttt ttgatcgaac tatttaaaaa agcaaaagag
    12781 cggaagatgc atactacatt ggatacatgc ggaaaacctt ttacgtatga agaacctttc
    12841 ttttcacgtt ttcaagaatt gatgaagtat acagatttac tgttatttga catcaaacac
    12901 atcgataatg aagagcataa aaaactaacg cattgggaca atgaaaatat tttagaaatg
    12961 gctcaatatt tgtcaaaaat caacaaaccg gtttggattc gccatgtact agttcctgag
    13021 cgaagtgatt atgatgaata tttgatccga ctagacaact ttattcaaac cttgtcaaat
    13081 gtagacagag tagagattct tccttatcat acgatgggaa aatacaagtg ggaaacactt
    13141 ggtttgaaat atccattaga agggatcgaa ccacctacaa aagaacgtgt cgaaaatgct
    13201 aaacgattgc ttcatacaga agagtataca aaatatttaa cgcgataggt cgcatcggaa
    13261 agaagataag tattgcttct ttccgttttt ttgctattat taaataggag aaatcacaaa
    13321 ggagcgaatg acatgtcaaa aattttagtt tttggtcacc aaaatccaga tacagatgca
    13381 atcggggcag ccattgcgtt ttcacacttg caaaatgaat taggtaaaga aacagaagca
    13441 gttgctctag gtacacctaa tgaagaaaca caatacgcat tagaccactt tcagctatct
    13501 gcaccacgag tagtagagtc agctaaagca gaaaatgcag atgtcatgct tgtggatcat
    13561 aatgaattcc aacaaagtat ttcagatatc agcgaagtaa atattttagc tgtagtagac
    13621 caccatcgta ttgcaaactt tgaaacagct aatccattgt actatcgtgc agaaccagtt
    13681 ggatgtacaa gtacgattat tttaaaacta tataaagaaa accaagtaac aattcctaaa
    13741 gaaatcgcag gaatcatgct ctcagctatc atttcagata cattgttgtt caaatcacca
    13801 acatgtacgc ctgaagatga agcagctgca aaagaacttg cagcaatcgc tgaagtcgat
    13861 ctaaacactt atggacttga aatgttgaaa gcaggaacaa atctaagtga taaatcagct
    13921 gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg gcagttccaa cgttcgtatc
    13981 gctcaagtca atacagtgga ccttaatgaa gtgatggatc gacaagcaga gctagaagca
    14041 gcaatggaag atgaaatgaa agcaaatggc tacgatctgt tcgtattagt tgtcacaaac
    14101 atcttagaca gtgattcaga attacttgtt gctggtaaag gaaaagaaaa agtagaagaa
    14161 gctttccaaa caactttgac caacaaccgt gctttgctta aaggtgtcgt ttcacgtaaa
    14221 aaacaagtcg tacctcaatt gacggctgta tttagctaat caaatggtag tatgaagcat
    14281 tcaaaatgaa tggataagcg attgatataa aaagaaacat agaacatact aaaggccgaa
    14341 gaaatggagg agaataacag tcaattatga ctcttgttct tcctcctttt tacgtaaaag
    14401 ccttttaagt aaaataaaac ggatagaaaa gagaacatat atgaactatt attcaaaaaa
    14461 taaggaaaac ttttatcaaa aactgaccga tgatccgctt ttttcttcat tgaccgatta
    14521 tctatatgaa catcgagaac aagaaacgat tctaagagaa ttgaaaaaag aattttcgca
    14581 aaataaattt tcccattttc ttgatttatt gatcgatgca ggattaatca agagggaaga
    14641 acgaagatat catttgaact ttccaatatt tgatcctaaa gattacttgc aacaagccac
    14701 ttcggctgct gaaaccatag ctgaacaatt gaagagactc tctgttgatg aacaaaaatt
    14761 agcgatggga gaagttattt gggcgtattg tttcgaagat gaacggaaag aagcgtattt
    14821 ttatggagta agaaacagcc gagagacaga attgctgagg acaactgcag gaaatgagaa
    14881 gtaccgtttt atcacacttt cctctataga acacttcccg cttactttgg ctaattactt
    14941 ttttgtacag aagaatcagc ttcctgtaac gaaggcattc aaagaattag ccgaacttat
    15001 tggagacgta aatgaatcgt acttttttga tcaaatagaa gttatcgttg acaggatacg
    15061 taagaataaa tataaaaatc gccggcctag tattttccat cagtctctac ttgtgacgaa
    15121 tactataaag gaagaagaat cattcacatt agaattacct attgtcgaaa aaaacaattt
    15181 tgagattgaa ttaccaacat tggatccttc attgacaatg gaggaaatgg cctttcttaa
    15241 acgacaaatc ttttctgagc tgagcaagaa atttataccg catgcatttt cttatatcaa
    15301 agaatatgga acagttttag tgagtaaaac ctaagagagc agtaagcaaa aattatactg
    15361 actcttgcag gaggagcctt tctcttcctt tatggttaaa agaattattt gagtattttg
    15421 cctatctacc acctattaga ttcactacat ggtctggaaa caaaggaatg caaaaaaatg
    15481 gtgagaaatg tggaatgaca aaggaagtag tgataagaaa agttagattt ttaaataatc
    15541 aatattatga ttcagtcaag tatggcattt tatgggaaga actagctgat tagattagga
    15601 agtccatttg ataatccaga atcactaaga aacgaatggc gagtcattaa taatttatcc
    15661 aatcttgggt tattctttta gattgaagtg tttaaaacta aaaaagcatt tatgaagtcg
    15721 taatagtcag gcttcaaaat gctttttatt ttgtttgttt tttctttgcc acataaatac
    15781 acctagactg acgatgaaga gcatatccaa cagatttcct gcgacttgga tcgtcgaagg
    15841 gttggtcagt ggcattaaag caaggacaaa aaaggaaaac aagctgtaaa taaaacaggt
    15901 gacaggaact aatcgaaaga agagcggaca tttcaattgg ctaaaaatga gtgaaaaaat
    15961 aaaataagta aaaatggata aaatcacgac taaaccattc atgataaaga agaaaagcgt
    16021 attgtgatta aacgaataaa aaagaattgc taaaaaagaa aacgttttaa atgcaatcaa
    16081 tacgcttgaa gcttcgttta acgtaccagg atgtcgatga aaaaaatagg caccgaaata
    16141 aacagaaaac agtaagccgc aaagagaaga caaaatcaaa aaaaacggat tttcttcggc
    16201 ttctgtgata tcagaatgat ccaaaagcaa ccagcctaat gcactagaag gcgcatgtga
    16261 ggtcttaagg tatgaataac atagaaaaaa taagatcgtc aaagttgcaa aaaaagagcc
    16321 taaatgtaaa aaattagtgg ttctacgttg aatttccata atatctccaa attaaattga
    16381 taagtatata aagtataata acaaattgat gagtatatgt cgatgttttt taatcaaaat
    16441 aataaataaa aactgtctaa catttaaaat ttaatttaga tattagacag tttttaagtt
    16501 tgtgagttat tttccttgtc gttttctcac ttttttagtc cagaaaccac ctgaaatata
    16561 ttttggctca taagaaatga taaaagcacg ctcttcgatt tctttgatca ggcgatacag
    16621 ttcacgttcg ctttttctag gagaaagtat ttcgagaact agccgctcac cttccagccc
    16681 cattgcagaa gtctgtgtca caccataacc gtgttctctc agtatacccg gcaaactttt
    16741 atcttctgcg ctatttgctg gcaaaatcgt tgtgaccatg atgtatccta atgccaattt
    16801 gtcttcaatc aaaattccga cactgatacc tactgcgtaa cctaacgcat agacaaataa
    16861 attcagtgga ttatctaaac gatctaaaac aagggataag ccgacgatat aaatcgtgat
    16921 ctcgaccata ctgacaagtg gagcaatcag tcgatagcct ttcattgtca acatgaaacg
    16981 taacgtgttc agagtgatat aagcaaaatt aatgaggaag atcatcccca acatttttgg
    17041 atcaatcatt tgtaaaactc ctttcattta tataacaaca atatcaaaaa aaatcgtaag
    17101 tgaagaaaaa ttgaaacttt atacatacaa aaaaatgata aaatgattat aatagaatta
    17161 taaagatagg ttaggtgatt aaaatgaaaa cggtcaatcg tgtgttttgt gccagccacg
    17221 tgctaagtct ccttctcagt atatacttag gtgtctattc gattcaacag ccaattgagg
    17281 tagagaacat tgtttttcag atgtcgctga cagatggttt aattttaagc gtttttttct
    17341 ttttgatact gtttattggt aatattttcg gtagcgttgc cagttttttg aatttttcta
    17401 tttatccact cctttcgcta gcattaggag tggtgggact ttgttctctg tgcttatttc
    17461 ccgagccatt cagtcctgca tttatattat ttggtacact gaacctgttc cagacaactg
    17521 ttggagcatg gttgctatgg cgatcaggaa atttaatgaa aataggtgag taacaattga
    17581 atccaattat attgaaacgt tctgtccatc atattccagt gttagaagtt gttctgaaag
    17641 aattaagaga ggaacgtatt cccgttgtca tctattatca cggatggcag acaagtaagg
    17701 agttagtttt gacgcaagga agaaaaattg cgcagcaggg cattcgtgtg atcctgccag
    17761 atgcgatgaa tcatggggag cgcaaacagc cggtttcttc tattccatcc tatacatttt
    17821 gggatagtat ctacggaaat ctgtttgaat ttgacacact tatcaagcat ttagaaaaaa
    17881 gaggtcttct acatgatcag cttgcagttg gcggggtttc gatgggggga atgacaacat
    17941 gcgccttgtt ggctaaacat cctcatatag tagcgggcgt gtgtttgatg ggttcccctg
    18001 cacctttgga atatggaaaa gaaatcgtaa ggcgcgcatc ggaatataat tatgtcgtac
    18061 caaaagacta ttttgatttg atttcatggg ttaagagcta tgatttgtca ttgcagccgg
    18121 aaaagttagc tggacgtcct ctgttctttt ggcatggaca agctgacgaa aaaatccctt
    18181 atatacaaac ggaacgattt gtagaaaaaa atcggcataa gtcttacgga aaagaaattg
    18241 tttttcgttc ctcaaaaaca cagcgacata tggtacaaat accactaatg gaagaagctt
    18301 ccactttttt agcaaaaaat ttgataaaaa agtataaata attgaaacgg aaaatcactc
    18361 atgacgatag aggattttcc gttttttatt ttgggctata ataaactctg ttaggaaaat
    18421 ttggtataat tgatagtaag aatgacaaca tgttagaaag gaagagagca tgcccacttt
    18481 agcagatgtt gcaaaacgtg ccaatgtttc aaaaatgacg gtctctcgag tcatcaatca
    18541 tccggaacag gtgactgacg aattgaaaga gttagttttc tcagcaatgg ctgaactgga
    18601 ttaccgtcca aatattgctg caaaagcact tgtcacgaat cggtcgcaga tcatcaaatt
    18661 atttatactg gaagaaatcg acacaactga gccctattac atgaatttgc tgatgggaat
    18721 cgctaaacgg atcggtaaag cgcattattc tctccaatta gttacaaatg atgccttcga
    18781 cgtcggttct tgtgatggat acatcatcac aggtgtcaga aaaaaagact tcgattggat
    18841 cgaccgtttg gaaaaaccag ttgtcttgtt tggggaaaat tctgaaggat atgattatgt
    18901 agacagcgat aatgaatatg gtacagcaaa agcaacgcaa tatgccttag aaagagatta
    18961 tcaaacgatt atttatatcg gtatcgaagt ggacgagcct tttgaaattt caagggaaac
    19021 tggttattta tctgtgatga aggaagttga tcttcctagt aaaatcttgc ggtttccaaa
    19081 tcattcgaca gaagtagaaa gatatatgac agaaaactgg gcagatttta cagataaaac
    19141 ttgttttgta tgtagttcag atcggctagc actaggagca gtaagaggga ttataaatgc
    19201 tggaggacac ttgcccgaag aatttggtgt gattggattt gatggggtat ttttagacca
    19261 aatcagttca cctaaattga caacgatcaa gcaagatatt atacgtatgg gtgaagtatg
    19321 tggagaaatg ttgttaaaaa aaatagaaga aaaaggggcg agtcaaggtt atcgtcgttt
    19381 ttttcctgaa ctagttatca gagagacaac gaattaagtc ttattactat atatatattt
    19441 atgaaattca tcgctatttt cttaaaataa tcagcgcatt gctactgaaa acaatgaatc
    19501 tgtgctatta ttgagaaaag ttccattttt gagaaggatg gtttgaatga aagaaatcag
    19561 acgaaaacat ttccgttttc ctgcgtacga tgatgagtta ggcgtaaaat taaccaacga
    19621 caagaagcga gtattatttg acggacaaga agatcttttg actgaacaga atcagtcccc
    19681 gtttgaacag atgaaagaat ttcatttcac gaacacgaac accgagaaaa tccgtcgcaa
    19741 gcgtcgtgca acaaatggat tgaagtcagc tccgcgtaag gaaaatttgg aaaagcataa
    19801 aggaaaatta ccggattata ccggccatta ccaatcagaa atcacatcga caggacgaaa
    19861 aaaacttttt ggtgattcct ctcgttctgt cagacaaagt gaaacaagga cagagtccaa
    19921 gcatactaca cgaaacgcat ctgttgacac gaaggtgcgg gagcgttctt attttgttcc
    19981 taaatatgta cccgcatcga ttatcccaga ccctagagaa agcaaaattt ctgaggatca
    20041 tttaatcgaa tcgatgaaaa aaacggatga ctcttatctg ttgttcgata cagaaccgac
    20101 gccgtatcaa gaaaaaagaa atggtgagcc gtctgtacga acattcaatc gaacaaaaac
    20161 gttagaggaa acaaagcagt cagaagaaaa aaaatcgaaa aaaagccatg gtatcttaga
    20221 acgctcatta caaggattga tcgatgatca aggaaactct ttgggagaaa atagctattt
    20281 taaataagtg atatacaaat ttatattcgg ctacagttgg aaaggaaacg ctgcggcgtt
    20341 tccttatttt atactctatc cgaaagttta tatcgtatcc tcaaattttt ttgagtttaa
    20401 gcgaattttt tctcccaata agtaagaaaa taatggcaaa ataaaaaaac aaactatttt
    20461 cgcagatcgt ttgcaaaaat agtt
//
LOCUS       DAFTHM010000044        20068 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFTHM010000044 DAFTHM010000000
VERSION     DAFTHM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.044"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            35..334
                     /locus_tag="L7C88_001546"
     CDS             35..334
                     /locus_tag="L7C88_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558383.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(431..865)
                     /locus_tag="L7C88_001547"
     CDS             complement(431..865)
                     /locus_tag="L7C88_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9558384.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1097..1807)
                     /locus_tag="L7C88_001548"
     CDS             complement(1097..1807)
                     /locus_tag="L7C88_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBP9558385.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1797..2657)
                     /locus_tag="L7C88_001549"
     CDS             complement(1797..2657)
                     /locus_tag="L7C88_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBP9558386.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2662..3300)
                     /locus_tag="L7C88_001550"
     CDS             complement(2662..3300)
                     /locus_tag="L7C88_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBP9558387.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3315..3614)
                     /locus_tag="L7C88_001551"
     CDS             complement(3315..3614)
                     /locus_tag="L7C88_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9558388.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(3657..5141)
                     /locus_tag="L7C88_001552"
     CDS             complement(3657..5141)
                     /locus_tag="L7C88_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBP9558389.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5161..5622)
                     /locus_tag="L7C88_001553"
     CDS             complement(5161..5622)
                     /locus_tag="L7C88_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBP9558390.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5640..6707)
                     /gene="ulaG"
                     /locus_tag="L7C88_001554"
     CDS             complement(5640..6707)
                     /gene="ulaG"
                     /locus_tag="L7C88_001554"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBP9558391.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            6925..7695
                     /locus_tag="L7C88_001555"
     CDS             6925..7695
                     /locus_tag="L7C88_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBP9558392.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(7968..8795)
                     /locus_tag="L7C88_001556"
     CDS             complement(7968..8795)
                     /locus_tag="L7C88_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9558393.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9363..10598
                     /locus_tag="L7C88_001557"
     CDS             9363..10598
                     /locus_tag="L7C88_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBP9558394.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(11597..11857)
                     /locus_tag="L7C88_001558"
     CDS             complement(11597..11857)
                     /locus_tag="L7C88_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBP9558395.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(11884..13185)
                     /locus_tag="L7C88_001559"
     CDS             complement(11884..13185)
                     /locus_tag="L7C88_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9558396.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(13477..13935)
                     /locus_tag="L7C88_001560"
     CDS             complement(13477..13935)
                     /locus_tag="L7C88_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBP9558397.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(13948..15279)
                     /locus_tag="L7C88_001561"
     CDS             complement(13948..15279)
                     /locus_tag="L7C88_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBP9558398.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15290..16732)
                     /locus_tag="L7C88_001562"
     CDS             complement(15290..16732)
                     /locus_tag="L7C88_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBP9558399.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(16719..17483)
                     /locus_tag="L7C88_001563"
     CDS             complement(16719..17483)
                     /locus_tag="L7C88_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBP9558400.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(17587..18462)
                     /locus_tag="L7C88_001564"
     CDS             complement(17587..18462)
                     /locus_tag="L7C88_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBP9558401.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(18717..18801)
                     /locus_tag="L7C88_001565"
     tRNA            complement(18717..18801)
                     /locus_tag="L7C88_001565"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18765..18767),aa:Leu,seq:caa)
     gene            complement(18819..18890)
                     /locus_tag="L7C88_001566"
     tRNA            complement(18819..18890)
                     /locus_tag="L7C88_001566"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18856..18858),aa:Gln,seq:ttg)
     gene            complement(18900..18972)
                     /locus_tag="L7C88_001567"
     tRNA            complement(18900..18972)
                     /locus_tag="L7C88_001567"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18937..18939),aa:His,seq:gtg)
     gene            complement(19034..19118)
                     /locus_tag="L7C88_001568"
     tRNA            complement(19034..19118)
                     /locus_tag="L7C88_001568"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19082..19084),aa:Leu,seq:caa)
     gene            complement(19139..19209)
                     /locus_tag="L7C88_001569"
     tRNA            complement(19139..19209)
                     /locus_tag="L7C88_001569"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19175..19177),aa:Cys,seq:gca)
     gene            complement(19255..19326)
                     /locus_tag="L7C88_001570"
     tRNA            complement(19255..19326)
                     /locus_tag="L7C88_001570"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19292..19294),aa:Gln,seq:ttg)
     gene            complement(19338..19410)
                     /locus_tag="L7C88_001571"
     tRNA            complement(19338..19410)
                     /locus_tag="L7C88_001571"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19375..19377),aa:His,seq:gtg)
     gene            complement(19413..19486)
                     /locus_tag="L7C88_001572"
     tRNA            complement(19413..19486)
                     /locus_tag="L7C88_001572"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Trp,seq:cca)
     gene            complement(19493..19573)
                     /locus_tag="L7C88_001573"
     tRNA            complement(19493..19573)
                     /locus_tag="L7C88_001573"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19537..19539),aa:Tyr,seq:gta)
     gene            complement(19575..19650)
                     /locus_tag="L7C88_001574"
     tRNA            complement(19575..19650)
                     /locus_tag="L7C88_001574"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19615..19617),aa:Phe,seq:gaa)
     gene            complement(19686..19758)
                     /locus_tag="L7C88_001575"
     tRNA            complement(19686..19758)
                     /locus_tag="L7C88_001575"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19723..19725),aa:Asp,seq:gtc)
     gene            complement(19768..19840)
                     /locus_tag="L7C88_001576"
     tRNA            complement(19768..19840)
                     /locus_tag="L7C88_001576"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19805..19807),aa:Val,seq:tac)
     gene            complement(19856..19927)
                     /locus_tag="L7C88_001577"
     tRNA            complement(19856..19927)
                     /locus_tag="L7C88_001577"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19892..19894),aa:Glu,seq:ttc)
     gene            complement(19942..20031)
                     /locus_tag="L7C88_001578"
     tRNA            complement(19942..20031)
                     /locus_tag="L7C88_001578"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19995..19997),aa:Ser,seq:gga)
BASE COUNT         6280 a         4246 c         3182 g         6360 t
ORIGIN      
        1 tttataatgt atcagtatag aaaggaaata aaacatggat tatactgttg aatttgacag
       61 tgaactactt aagcaatttc cacaagaaga acatttcatg tataaagaag caatttccca
      121 caaagtgaca gagtatttgg agcataattt ttttcgtata aagccagtgc gtactcgttc
      181 ggcaaaagga atatacgaga tgaaagtcaa aattaataaa aaaaattatc gcatagcatt
      241 tgctttaaaa aaaaatcatg tgttcatttt ttatattagt tcgaatttgc aaaaaattgt
      301 atttgataaa gaggtgagta aaaaaataaa atagctgagc attggaggat agattgagtg
      361 atactaagtc tatcctcttg tttttctaaa gaactaagct agaatttttt cttttgtacg
      421 ttattatatg ttatttgtca ttaccaaaaa gcaccttttt tcttctagta tctatgacat
      481 aagaaatacc acccatttcc tttacttgaa caaatcctac tgattcataa aatttttttg
      541 ttttctcagt atcatctgtc aataattcga tttggactgg tccataacta gtgatcttct
      601 ccaaagcttc attcaaaagc actttgccta ttccttggcg ctgatacctc ggatgaatga
      661 ggatatcttg aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg attccgataa
      721 tcttcccttc cccattacgc tttatcagag attcagattg ttcaaatgct ctagctaacc
      781 ttgcagtgtc ttttgtgtaa ttcgtccaac caacgctctt atataattca gaaatctcat
      841 cgatcataag ggaatcaata ttcatttttt tcttcctttc ttatacaatt ctccctctaa
      901 taatacagtt ctttgactat ttaatctatc acatataact ctcctgtaaa gattctctcg
      961 attccttaaa attcctcttt ccttttagaa tgcatacttt ttgataaata aaaaggttgt
     1021 gataaatttt cttcacaacc tctgtttctc tctatcaagt gttatctttt aattttctac
     1081 ccttacccta gcatctctat tgcccgtagt atgcatactt tccatgtttg cgaaaataat
     1141 gtttatctag taaatattgc gggatttcac atatattggg gttgatcagc tcgttttctt
     1201 tggccatcag acaaatttca tctaagatca aactgttttc tactgctttc ataggtgaat
     1261 ccccccatgt gaacggtcca tgtccataga caagtactcc agggacttcg tttggatcta
     1321 attttctttc cttaaacgtc tcgacaatca cattccctgt atgaacttcg taagcttctc
     1381 ttacttcttc tttcgttaat tggcgtgtac aaggaacctt accataaaaa gcatcagcat
     1441 gagtcgtgcc ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg
     1501 aatgagtatg agtaatagca gttatatctt caaaagtttg atacaaaaca acatgtgtgg
     1561 ggagatctga agatggtttt aagctatctt cttctattat atttcccgac aaatctgtta
     1621 ccaccatttg atctgcttgc atgcattcat atctgacacc gcttggctta atgacgatga
     1681 ctcctagctc acggtccact tcactcacat tgccccaagt caatttgact aatccgtatc
     1741 gcggcaatgc cagatttgct tcaaggacac gttgcttcat tgctgcaatt ttttcttcac
     1801 aagacatcat agccagcctc cttcaattta gaacttaagt agtcttttgc ctgctggatt
     1861 tctcttcgaa agtcttggct tttttcactc cacatttcaa tcagaaatgt tccatcataa
     1921 tctagacgtt tcaaatgtct taataatcca agaaaatcaa cacaaccgct accaaaagga
     1981 acatcacgaa actggcctga atattctttt gttacagggt aagtatcttt taagtggata
     2041 gcagtgatat aatcgatccc tttctcaagt tctcgagccg gattattttc cggccatgcg
     2101 gacaaattgc ctaggtctgg atatacttgt agaaaaggtg aatgaatctg ttctttgatt
     2161 tctaaaaatt ttgaaatgga gttcataaat ggatcatcca tgatttccac ggaaagaatg
     2221 atgccatatt tagaagcttc ctttacgctt tcttttattc cttcgataaa gtcttctctg
     2281 gaattcattg atttctcttc ataataaaca tcgtatccag ctatttggat tactttgacg
     2341 cttagattat gcgccaaatg gattgctttt ttcattagtt gtttcgctgc ttttttcttt
     2401 tctggatcag cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata
     2461 cgtacaccgg agctgaacat ctcttctctc agctcagcta tcttttcttc agaccaatct
     2521 aatcgtgcta accgctcatc cgtctcatca atcgacatct cgataaaatc gaagtccatt
     2581 tcttttacaa gggaaaaacg ttctttccat gaaatatctt tgggtaacgc tttttcataa
     2641 atcccaattt gagccatttc cttaccccca gatacgaatg atctcatctt tgaagttttg
     2701 tgcggccttc atcggatcat ttgctgctgt aataccacga ccagtgataa aggtatacac
     2761 atcgatccct tcaaataagt gtaatgtgtg tggatttaat ccaccagtta cagaaacatt
     2821 aaagcctagt tcaatcagtt ttttgatctt cgataaatct ttttcacccc aagtttcacc
     2881 agataacagc gcatcacggc tttgatggta gattacctgc cggataccga tgttatgcca
     2941 atccatggct tgttcaaaag tccaattgcc gtagagttct acttgcaatt cacctatttc
     3001 tttttgtgct gcctccatag ttggaatcgt tgcacaacaa atgactgtca tccagtctgc
     3061 tcctgctttt gcaacattac tcgccactgt tcctccagcg tctgcacatt tcgtatcagc
     3121 gactagtttt ttatctggga acatactgcg aatacagcga atcgcttttt gtccttcctg
     3181 taagcaaaga attgtgccca cttcaataat atctactaca tcaccaactt tcataacatc
     3241 tcctaatgca tgttctaagt cattgtgatc taacgcaatt tgcaaattcg gcctgctcat
     3301 cttagttcct tcctttactt gtttttttgg taccactttg tttcagcaaa tttttcactg
     3361 atttctttga ctgacatcac atttttgata ccgataactg taactccttt tttctctgcc
     3421 tgagtaaaca tattcaaaaa attgactggc gtaaaaacta catcgtattg gccagctgaa
     3481 ctttttccct ctgaaatggc acaatgatgg attttggtaa ttggtacgtt tagttctttc
     3541 attgcttttt ccacacttct catcatcatc aagcttgttc ctgatccatt tgcacacgat
     3601 actaaaattc tcatcttaat ccctccatta tgagtgttgt ctaatcagat tttcttttat
     3661 actctctgct tttctgcata tgtgtcatag tcttctacaa tcaaaaaata accatcagga
     3721 tttttccgat attgtaactg cggaatagcc aataaaccaa tgacaactac ggcaattcca
     3781 gcataaccta ggactttcat gattactgta aacaatggcc aagctgttgc ccagtcgaac
     3841 atcccgatat aaccaccgta tgttgacatc ccaatccatg tagcgaataa tgctgaaccg
     3901 cctacttgta tgattcctga aagaaacggg aacaggcaag cggctttgaa tccacctcgg
     3961 ttattggcat aaactgctat aacggcatta tcaaagaaca acggaatgaa accggctatg
     4021 acgatcgttg gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg tcccaaagca
     4081 ccaaacaaga acccaatcgt taccgcattt ggcgaaccaa agccaaaagt agcagctacg
     4141 tcaattcctg gaacagctcc tggtaaaatc gtgtttgaga ttccttggaa agattgagtt
     4201 agttcatcga cgaatgtccg aacacctaat tgcaagatcg ccagatatac cgcaaaattt
     4261 aaagaagtcg tcataatgta gaataagaaa ctctgccctt cttgcatgaa ttgcgcttga
     4321 atcaaataat ctttgcctag tacaatcaga atgatcccaa agaaaaatag catgagtaac
     4381 gaagtagcaa ccatattctc attgaaaatc gacaagaatc ctggtaattt gatatcttca
     4441 atttttttgt cttgcttgat tgatctattt ttcttttcat cccgcttttt catccactca
     4501 gctaattttg caaatataaa gattccgaac atttgctgat gtgccactgc aaatccggca
     4561 ccttctgtca attcctgcgt gattcctact gttaagttag aagctactgt ccaataacaa
     4621 cctaaaatca gtcccataaa aatcaatgct tgtatcctac ctagatcagg aaagcaaaac
     4681 agtaaaatcc aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg
     4741 gaacgcagtt tcgtatattt ctgaaaacgg actaataaga tatttaaaac aaatgcaatc
     4801 agtaataaaa tcatcacatc tccaaaggta cggccaaatg tctccattaa tccagcatcc
     4861 acagcatttt gtccaaaata aggatctgta accatggcat ccaaattgaa ccgttccttt
     4921 agtccaacca agattggccg aaaattattg accaaaccac cagagccaac agtcaaaata
     4981 aagtaaccga ccgttgcctt taagaatcca gcgatgcatt catgaagcgg gcgtttcagc
     5041 aaaatatagc ctaataacac gataaaacca atcaggtatg ctggctgcgt caagatattt
     5101 gttgcaaaat acgtccaaat gcttaacaaa aattccccca tcttttttct cctctatcaa
     5161 ttaattatat tctgccatca caacttggta atcatcgatg gagttcgtag agatgagacg
     5221 ctcaaccaat ccatctgtca ttaataattc ggataatttt tggatatttt ctagatgttc
     5281 ttctggatct tttgctgcga gtgtaaaaaa caaactagcc gttttctcct cattctcccc
     5341 ttcactttca aaacggattg gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac
     5401 accatcactt ttttctgaag aatgcggcat tgctacttga ggtgcgatca caatataagg
     5461 accgtatttt tctacacaat ggatgatctc ctccacatac gtttcatcaa taatttcctt
     5521 atcgatcaat acaagacagc tttcggcgat agcttcacgc caatccgtga tttctttatc
     5581 tgggtaatga atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct
     5641 tataaaaacg acggaaacgg tgtatcattt tcaatcgaga agacatcttc aaatcctcga
     5701 taaaaattaa actcaagatc atctttgttt gtcggataga tgaatttccc gcctacttgc
     5761 cagatataag gtttaaatcc atacttcagg cgatcctttt tgaatttcca aatttcagtg
     5821 atctcttttg gatcagccat aaaattagac caaatatcgt agtggacagg aatcactact
     5881 tttgcattca atgactccgc catgcgcagc atatcaacag aagtaacttt gtctgttatc
     5941 cctcgtgggt tttcaccata ggcccctaaa cagacatcga ttttgtgttc attaccatgt
     6001 ttggcaaata aattggagta atgtgaatct cctgcatgat aaagattccc tcctgatgtt
     6061 tcgaataaat agtttactgc aatttgatcc atctcctgag gcatttttcc ttttaatacc
     6121 tcttctggat cttcacaagt gaccaacgct gtccgatcaa acgcttctaa agctactaca
     6181 ttgatgtctt tgattttgac tgcatcacct ggctttactg taatcgtttt ttcttcagga
     6241 attccccatt tttgccacgt gcgaaccact tcttttggcc caatgaatgt tgcttcagga
     6301 caattttgat gaactgctgc ggctgtatgg atatctagat gatcggaatg gatatgtgta
     6361 acgattaaag cgtctacatt ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt
     6421 aaattaggct gcatattttg aacgccactc atacgcatca tctgatggcc ttttttcatc
     6481 atgccattcc catgactacg ttttcccgtc ccacaccata gatcacataa aatattcgtt
     6541 ccttcatgac ttttcagcca aattcccgta cagcccagcc accacatagc aaaagttcca
     6601 ggatccacta cttctgtttc gatttcttca ttcaagtatg tgccccactc aggaaatgtt
     6661 tctactaacc acttttcttt tgttacttca ttgacagttt tactcatttg cttgctcccc
     6721 ccatatcgtt gttccaactt acaagtaaat attaatgtgt atcagcatcc atgaaaaccc
     6781 ttttatatga ccgtttgttt tttatatgat tttctttcag taatcaatga ttgtttcagt
     6841 ataataaaga cagatatgaa tgtttaaatg aacaactagt caaataaatc catggatcaa
     6901 gatgtccctc aggaggcaaa agtcatgaaa aactcacttg tcaatattga aaaacgtcaa
     6961 aaagaaattt tggaactgct tcagcagact gaacaactat caactttcga attagctgaa
     7021 tcccttgatg tatctattag tacgatacga agagatttaa atttattaga agaaaaaaac
     7081 gagatcatac gcaattacgg ttattgttct tataattaca aaaaccagac tgattttgat
     7141 caatctggtc ctgaaaggat taaacaagcg attgccagag aagctagtaa atacattaac
     7201 gattatgata cgctgtttat caattctagc tcgactgcgt tgaaaacact ggattttctt
     7261 caatctaacc atttgacagt cattacaaac aacgtgaaaa tcaattactc tccgcacaaa
     7321 gataattgta gttatatttt aactggtgga gagatgcgct ttccaaaaga agcactagtg
     7381 ggcgacatcg cattaaatac gatttcttca gtcaatgcag acatttgtat cattggctgt
     7441 agcggagtcg atgtagtaca tggggtcaca acaaagatat taaatgaatc aacgatcaac
     7501 gaaatgatgg tcaacaagac aatcaaatgt aagattttag tcgctgatca tcgaaaaatc
     7561 ggactgacat caaagttcaa gattgctgat atttcagtct ttgattattt gatcactgat
     7621 aaattttgtt ctgaaaaagt attagaggag atcagaaata cggggataaa aaccattcaa
     7681 gtagattcat tttaagaacc aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat
     7741 aacaaattta tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga
     7801 tgtatccatc caatcgatac catcataatc tattgcttct tttataaccg ttatatgttg
     7861 cctaaatagg aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca cacctccttt
     7921 tttcgaataa acggtattca aatcagaaca ctgatttcac aaccacttta tttcaggtcg
     7981 ttttcaatca cctttaccgc gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc
     8041 atatatcttt ctaaataatc atcttctcct aattgcttat ggcaagaagc aatttcataa
     8101 agcaagtatt ccaatgcata agtcgattta tgtttcttat tatactcaat acccttctca
     8161 cataattgga ttgctttatc ataatcctcg attttacggt aataggtggc gatatcataa
     8221 tatacaatgc agaccatcag attatcaaaa tcagtctcac tcaatatttt aagtgtacgc
     8281 tccacataaa ctttcgcaaa atctaattct ccttttgaca agtagatcat tgccacgttt
     8341 gcagctgctt gtaagtgatg gatatctgtt tcggtcgttt gttccaacac ttgattaaaa
     8401 taaaataatg ctgcatctgg ttttttcgca taaagatgat caagcagtcc ttgataaaat
     8461 aaaatttgat ttaaaagatc agaattactt actttttcct gatcgatcgt ttgtaaaatt
     8521 ttataagatt cttggtattt tgatacagaa ttcaatgatt gaatctcatt tatttttttc
     8581 ctgattttgt cttcttctgt ttctactaat atatcggaga tctcgacatt cagctttttg
     8641 caaagcgcac ttaagatatt gatgcctggc gacatattct tgttttcgat attgctgaca
     8701 gttgcttgtt cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt tttctttcgg
     8761 tattctttta gtaatgctcc atctacttta atcaaaacaa tttccttccc tttaaaaaat
     8821 tatttctcct ttatatcata cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca
     8881 gaataaaaat tttaatttta aaataatatt caaattaaac aactggcgta tctgctcctt
     8941 gatttctttt tgtgttatct gaataattat cgtttacagt tataacacat agtgaaaatt
     9001 gtcatggcga gaaagtctaa gaatattttt aaacataact atttctttct tacgtgtgta
     9061 taatgacgac agcacaccta tcaattaata taattatttt atttttttat gttctcatgt
     9121 ttatttttaa tgacacaact tctcgtattt atctggcaca acatataaat cgatcaaaaa
     9181 attgttgcgt gtttttttga aaattggagt ttcaacttga ttacaaaatt taaatttaga
     9241 agttgtgaaa acagcgagag acagtttaat attcaaaata tacataggct actcgaacgc
     9301 tgtgtttttt agtatactag taagaaacga agggatagac tcattccaat aaggaggatt
     9361 tcatgaagac aattcttttt gctcctgcag tattcaattt agctgagaca acacgaatga
     9421 ttgaggttgc caaagctatg aaagaccgtt attactgtgt attctttggc ttttctaaaa
     9481 cttttgctcc tttgatcaca gaaagtggct ttgagtatca tttactagcg ccgatcctta
     9541 cgaaaaaaca agaagaacaa atcataaaat ttgaccagtt gcgtacactt aaaaaccctt
     9601 ttaccaaaga aatggttgcc tctcgtatca ctagtgaaca gagtctgatt gctaagtttg
     9661 agcctcgact gattgtgaca ggttcgaatg tgacaatttt tttatcggcc cgcaataaaa
     9721 agattccttt agtatatgtt aaaccctatg ctttgagtga accttttttt caatcagagc
     9781 atgcgctgat gccccacgag ttacgtttct tcggcccttt aagcaatccc ctttggcact
     9841 ggacaaaaaa gcgtatagta aatacccgat ggatccccaa tgccttcaaa cacgctgcac
     9901 aaaaagaaat gcttccttta ccaaaaacaa gtttacaaat gatggatgct gatctaaatc
     9961 tcatcacaac gcctaaacta tttttggaag aagaacagct gccggaaaat tatcgaatcg
    10021 ttggtccaat ttttgctaag ctcagtactt ccttgcctga agaagtgcta acttttatac
    10081 agcgaaagca acaagaaaga aaacgtatta tctatttcgc aatgggtagt tcaggcaatc
    10141 cgcgtatgtt acgcaaaatt ttgttcttct tacaaaaaca accggatcta gcggttattg
    10201 cacctattga ctatctgctt gatgacattc aatctgactc agaagatctt ttaataacag
    10261 aatatctgtc tagtcatctt ttgcatgaat tcattgattt ttcttttatc cacggcgggg
    10321 aagggaccgt ccaaactgcc tgtgaatccg gcaaaccgtt tatcggtgtg gggatgcaat
    10381 ttgagcaaag ctgtaatatt gactattgtg taaaatacgg aaacgcaatc gccctcacaa
    10441 aaccagtgac tgaaagaaaa ctgcagattg ctctgcgcga agtttcttca cccaagattc
    10501 gtcagcaggc acgcacgctg caagccgttt ttccaataaa tggtccacaa caagcaattc
    10561 aagaaatcga aaccttcctg agcaaccacc caatatagtt tcaagtagaa aaagcttttt
    10621 taatagagac tcatcagtaa tttcgctatt cgagacccag acagtgaaaa tacaaaaaaa
    10681 gtaaatagtg gattgaaaag ttagagttac ttaaattacg gtgtctaaaa aacacaaaat
    10741 catccttaaa ataaaagatc tgacgctatc caaatgagca taggtagcgt ctgccattta
    10801 ttcttagtca aattctttga cacctttctc tggttggatc atctcaacgt ttcttcaaaa
    10861 gaaagaccat aataattagg caaatacatt ttcttaaaat gtgtcatata gatctagaag
    10921 catcgctttg tagagatttg tgccgctagt cccctcaaca attactaaat caaatgtagg
    10981 atttaccact ttatctttga taatcaacct ccctcttctg ttgagacaat gatctcgcaa
    11041 tccgatgcat actcctatat aaactgccag caatccccac atattgagta gatcatgtca
    11101 gaatgttcta tgtcgtcagc aacgatacac taaaagtcac gttcaccatg actgattgct
    11161 attcccagca caattatttc tatacacgtt tcatgatttg aataaacact cacatcatac
    11221 atattaccat tcatacacca tactgcagcc cctactatat ggttgtaagc tcccaaatct
    11281 atatttgact tgatcacttt ggtagtagat ctactaattc taaatccatt gctgataaaa
    11341 tttccatttt ttcctccttc tttctgccaa aacagttaaa acaataataa tctttatgta
    11401 aaaaagggct gtgacaaaag ccttgtcaca gtcccatatt ccgaataaac ggtggtcaaa
    11461 agcttgcatc tgcggtaata agttcaacca aacgaaaaat aagccaacat ttcacaaaaa
    11521 tttaagaagc aattttcgta aatttcttct tatttcttga agctaaccac ttctgttaca
    11581 accactttta gaacatttaa agcttcgatg tgacaaacca tctatgctgc tcgatcataa
    11641 aattgatagc aaaaattcca caaagtacat atgtccccca tgaaaacaaa acattcatat
    11701 gcggtacaat gatctttgga agaatcacga tcaaaaatga tgccagtgcc caaatccatc
    11761 gattgatttg aatatgatat gtagctagca tattcaatat aaggtgacta gccgttaata
    11821 aaaagataaa aacaaaaaat aaaatcagcc aatacattgt ttcccacctt ctaaaaacca
    11881 aacttagaca gtctggactt cgttttctcc acgactttgt tcatctgaca gcatcttttt
    11941 atcataagct tttacaaatg gataatagat aataaatgct atcaatgtgt tgatcatgat
    12001 caagataaca acacgccagt catttcctgc tgaaagataa ccgccgattg gagctggtaa
    12061 tgtccatgtt ggcaaaacag taaatctatt gaccatttct aatttgactg caaaataact
    12121 gataatagtc aaaactaaag gaactaagtt gaacgggatg aacatgtaag gattcaacat
    12181 cataggagct ccaaaaatta tgggctcatt gatattgaag ataccaggaa taatagaaaa
    12241 acgaccaacc tctttcaaga attttgattt acagaagaat ataaacaaaa cagataccac
    12301 gatcgttgct cctgcaccac caattgttac cgtccattga taaaactgtt caggagcgat
    12361 atagggtaat tgggtggcag ctgtaccatc tgccaatgcc tttgcattct catccaacat
    12421 gatcagccac attggacgaa caacagcccc tacaatactc atgccatgga taccaaatga
    12481 ccacaacaaa tggatcaaaa acattggtag taaaacacca agcaaattat tccctaaaat
    12541 attggttaaa ggctcgaata acgataataa ggcagcgttt acatcaaagc ccgcgacgct
    12601 tcgaatcagc caagtaattg ttaaaatgac tgcacctgga atcaatgcct caaaactacg
    12661 ggcaacagca ggtggcactt gttctggcat tttgatagta atatttcgat ttttaaagaa
    12721 acgatatact tccactgcaa aaatcataga taagatcccc gcaaacatcc cagatgctcc
    12781 caaagaactc ataggtaaga cccagccaag aggtgcctct tcaggagtta aaacgtttac
    12841 aggaacttgt aacataaaga acgttcctaa agataatata ccacctgtca cactatctaa
    12901 tccatatgat ttagctagat ccgaacccat aacaaaagtt gcataaatag ccatcaatcc
    12961 catcgtcatc ctaaagggta aaacaatcgt tgccgaataa ggggcaataa attcattcca
    13021 tccaggaaac ggtaaattga taaagaccat aaaaaatgtc ccaatcaaaa tcaatgacaa
    13081 tgttgaaaca accccattac gaattgctaa taaatgacgc tgtgtaccaa tttttgccat
    13141 tggtgggaca agtttctctt cgacccattt catcagcttt tccactaaaa ccactccttt
    13201 tcaataaaat atgaaccatt cattgcatga caacgcaaag aatgttcata actaattata
    13261 taattaagaa attttatttc aatatattct cttaaataat caaatttatt tttaagaatc
    13321 ctgaaaataa gttttctaaa tcataggagc aacaaaaaaa ttcgataatt aacaaaaatc
    13381 aaaatgatta aatctagtga ttgaaacata tcatttcaaa aaaattttgt aaattcaccc
    13441 ataaatatca ccctatttaa cttttttcat cgtacactaa aattcaaaac aactatcttt
    13501 aatctttact tcttggtttt gttttaataa atttccttca aaaatgcctg gagaaactac
    13561 aatgatcacc gtatcttttt gtgcttgctc caacttcttc aaatctataa tagctaacag
    13621 tgtcccttct tttacctcct ggttactttc aacccgtatc tgaaacggac ttccttcgag
    13681 ttcaactgta tctaaaccca tatggatcag tatttttctg ccagattcac tttcgatcgt
    13741 tatggcatgt cgggtaggaa atatattatc gattattcct ttaactggcg catggatata
    13801 tccatcatga ttcgttatag cgtatccaac tcctatcatt tttgaagaaa agacctcgtc
    13861 ttttactgct gttaatggaa taatttgacc actagctaca gcttttagaa tgtttcttgt
    13921 tttaaagaaa tgcacttttt atcacctcta ctttaatgct ggccaatatt ttttgtttac
    13981 tttgatcatt tcatctagta ttttttttgc gactctggca tttggtacgg tttgattcaa
    14041 tgtaaatgct tgtaaagctt tttgataaga accttcaaag taagcatcta ctagtaactt
    14101 ctctactgca acttgtgcct ccatcaatcc tttatgaaaa tcactgattg gttttcttag
    14161 tgtaattggc tccacaccag ttgcaccaac atatgccggt atttcaacaa ctgcatctga
    14221 ccgtagattc ggaatcgccc cttgattagg aacgattagc ataaagcgac gacgatcatc
    14281 attcaacaag gaaatagcta tatcgacgat atattgtcca tgctccccaa aattaaagtt
    14341 caatacttct tccacaatac cgcggcgtat tttatcagcc atttctttgg tatttttctc
    14401 tcgtccatcc atgaccatat tagcacgtgt atactctttg tcagtatgct caacgaccat
    14461 atcaggatat aagtaatact ctaagtaatt attcgggata ttacttggaa aatttttcgt
    14521 gatgactgac atcatttgaa aggttttttg ccaagtttta tctcctatat taaaatcggc
    14581 gacttgcatt tcttttgtta ttagtttttc aataatctct ggcataattt ctcgttgcaa
    14641 ttctttatca taaatcgatg tataccagcc aaagtggttt aaaccataat acgtaacgat
    14701 ccaattctta cgatcataac cgtaattcac tgcaatcgtt tcttcaattg aaatagtcat
    14761 atcacaggca ttaatcattt ttacattcgg atatttacga cgaacagctt cagaaacgat
    14821 cgactctgga tttgtataat tcaaaatcca tgctttgggg gcatagtctt gtatatgatc
    14881 gacaatttcc aataaacctt tgattgagcg catcccataa gcaaatcctc cgagtccaca
    14941 cgtttcttgt cctactaatc catgtttaag tggaatcttt tcgtcctttt ctcgcatctc
    15001 caatcctcca acacgaattt gtgagaaaac aaaatcgcat cctgtaaaag caagctttgg
    15061 atcatccgtt gcacgaatgc gaatatttga aaaacctttt cttttcagca taaatttaac
    15121 aatcaagtac atatccatat ttctttcttc atcaatatca tataaacgta tttcagataa
    15181 tggcaaccgt ttttcattgt tcaaaatggc ttgaacgatt cctggtgtat acgtactccc
    15241 gcctccagct atagtgataa tctgtttttt catcatcatc ttttcctttc tattcttcta
    15301 ataatttatt gaattctgcc ataacataag tcacttctaa gccgatgata atttgataat
    15361 ttttttcagt tggtttaatg atcccgctta tccctaattg cttgattcgc tgttcctcga
    15421 ccatggtggg atccactacc tctacccgta ggcgtgtatt acaactatag acatccagga
    15481 tattggcttt tcctccaaac gcttgtagca tttttgttgc catatattca taatttttac
    15541 ttgctaaccc taactctgtt tcttctaagg ttacttcatt gccaaactct gccttagctt
    15601 cacgtcctaa tgtctgaatg tttctcttat tgatcaaata ataaaaagta acgtaataca
    15661 aggcaaaaaa gaaaattccg attggaagaa tcaaaatagc attggtagcg attcgaaaat
    15721 tgatgagata atcaacaata catgctccga atgtaaaacc aattcgtata ttgaataagt
    15781 aacagacaat ccctgctaaa ccggcaaaaa gtgcatggat cacgtacaac ataggagaaa
    15841 gaaacatgaa actaaattca acaggctcag tgatatttgc aataaatgaa gttcctgcac
    15901 cgcttcccat gattcctttg accatctctt tattttcttt ataagctgct ttatagatag
    15961 ctagacatat agctggtata ccaaacatca ttactacaaa aaaaactgat aaaaacagtc
    16021 cagcctgagg atctccgttg ataaagcgtg tcatctctcc tctgaaaact tccttgctag
    16081 gagatgtata gcttcctaaa tcgtaataaa tatacgtatt caacacatgg tgcagtccaa
    16141 aggggatcag caaacgattc aaaaacataa atatccccac acctaatgct cccatatcaa
    16201 cgagcagttt tgcaaaatta tcaatcccaa tttggatgag cggccagata aagcccaaaa
    16261 aaacagctgc gattgtttgt agaatcatca ccatagtcaa tgggaatttt tcgcccgcaa
    16321 aataagaaaa aactactggt aatttttgtt ctttaaagcg attatacgtc catgccgcta
    16381 ctaaaccgga aataattcca ccaaaaatcc ccatattcac ttctgggtcc ataatttcta
    16441 agcctttttt caaggtagca atcgctaaaa aaccagtaag tgcaggtatt cctttgtcct
    16501 tatttttgac aaaaccgatt gcaactccta tagcaaataa gatatccaag tttccaaaaa
    16561 cggcatttcc agctgcacca attactggga tgttcagcat atcgtcagct gataaacgca
    16621 tgatcaatcc cgctaatggc atcgctgcaa ctggaagtag catcgctctt ccaagcttct
    16681 gcacatttga tttaacattc atttttattc ctcctctatt aaatatcctc atatgttact
    16741 aactcaatca aaggatcatt tttcactttt tgagcaaatg ctgaatgaat taaaaattcg
    16801 acttggtggg tacgaggata cacaaaactt gaaccattta acaattcctg atccaaatac
    16861 gctgcgtgac acatgacttc gatcgtttta tcttctctca atatcatgag taaacttgcc
    16921 aaatattctt ccacactcgt attgatttgt cgtttttttt catcagtttc tcctacgaca
    16981 tcgaaacaag gctcaaaata atcgacatga cgaacttcat cttttcgttc aaagttgctc
    17041 cgaaccggca aatcatattt ttttgctaat gtaacaacta cctcctgatt ttcatccaaa
    17101 gtatgagtat gatgatgact gtctaaatga gttggtatga tccccgcatg ataaattttt
    17161 tgaatctgag cattccattc ctgatacagt tgatctttgt caatgttaaa tggatgctga
    17221 taataagata aggatctgaa ctctccgctt tcgataagag tatcgacagt tttgaggagt
    17281 ggtttgccac acgtcaatgt taaatggact cctacaccta gcctaggcat ttcctttctt
    17341 agtttcacag catgctcgaa acccggcata tttgccatca atgtagttga tgtcaaaatt
    17401 cctcgctgat aagcatccat aatcccataa ttcacaccat ggctatagcc aaaatcatcc
    17461 gaattaaaaa tcacttttcc catttcattc tccttctttt ttctactaaa ataggcgcaa
    17521 ccaaataatc atagtccatt tactatgtgt catttggttg cgcctataga tagttacgcc
    17581 cttattttaa tagattcttg ctagatgaat tgccaaatag atgatttcat tttcttgaat
    17641 ggcaagttga aattgctgtt cgatgatatc tttaatcttt agtgctgtac aatacgcttt
    17701 gctatgttta aatgtttcag taaaaaaacc aatattttct actggcgttt cttcctgata
    17761 aatcaagcgt ttaaccagga atttgatatg aaccattaag cgatgataag tcagtgattc
    17821 tttatcataa acgtttgaat aggatttttc tagatgggac aaaatcgtgg tcgtcatttc
    17881 tactattttt aagctcttta aactattagg ctctcctagc tcagcattaa tgatatgcat
    17941 agtgatgaat cctacttcat ttgaccctaa ctcggtttga tatcgatgat tgattcgctc
    18001 gaccacttct actgctatat catattcatt tggataaagg aatctcattt ctggcaacat
    18061 aattgctgtg acatctctat cttctctttt tcgttgaata gcaaaataaa tatgatctgt
    18121 caatgtaata tagatatttg aatctaatgg agaggagatc ctagctgtta tcagttcaat
    18181 cacttcttcc gcaaaatcca taaattcgat tggaatctgc gagactatct cactgaatcg
    18241 tttgatcttt tctttagaat ctaatacaaa taatttgtca gcatcctcaa catcaaatgg
    18301 cttactcact ttagcagaaa agccaatccc tttccccatc gcaatttttt ctattccatc
    18361 gtcatcgatc aatacagcat tatgattcag ctttttcatc acatacaccg ttaattcacc
    18421 tcctctatat gataaaacaa aacaacttgc agactccttc atacatattt ttgtctccaa
    18481 acaattttta aagacaaaaa acgacctaag aaagaaccct ttcttaggtc gtgcctaatt
    18541 gaatagtagc accctacata atttacaaaa atagtttaac acataataaa agcgttatca
    18601 atatcttttt tactcgtttt atgataatac ttgtatcgaa ttgatttgga ggtaattaca
    18661 taaaaacaaa aaaaatatag caactctcta taagaaagtt gctatattga taattatacc
    18721 ggcggccggg gtcgaaccgg cacgtcctca acggacactg gattttgagt ccagcgcgtc
    18781 tgccaattcc gccacgccgg caaatttaaa aataataact ggggtagctg gattcgaacc
    18841 aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca agaataaagg
    18901 gcgaatgatg ggaatcgaac ccacgaatgc cggagccaca atccggtgcg ttaaccactt
    18961 cgccacattc gccatcataa aagatgttat ttaatttctc aataaaaaac taagatgaag
    19021 acatcttagt caataccggc ggccggggtc gaaccggcac gccctcaacg ggcactggat
    19081 tttgagtcca gcgcgtctgc caattccgcc acgccggcaa gttgatttat tagtactaag
    19141 gcggtaaccg gatttgaacc ggtgatgaag gttttgcaga cctctgcctt accacttggc
    19201 tataccgcca ttatactatt atcaatctat aaaataaaga ataaattata gaaactgggg
    19261 tagctggatt cgaaccaacg catgagggag tcaaagtccc ttgccttacc gcttggctat
    19321 accccaagaa taaaaagggc gaatgatggg aatcgaaccc acgaatgccg gagccacaat
    19381 ccggtgcgtt aaccacttcg ccacattcgc catggcaggg gcagcaggaa ttgaacccac
    19441 actaacggtt ttggagaccg ctgttctacc tttaaactat gcccctataa aatggaggag
    19501 agtggattcg aaccactgaa ccctaaggaa cggatttaca gtccgtcgcg tttagccact
    19561 tcgctactcc tccatggtgg cgcgggacag aatcgaactg ccgacacacg gagcttcaat
    19621 ccgttgctct accaactgag ctaccgcgcc atattttaaa attattaatt gaataacaag
    19681 aacgacggtt ccgacgggaa tcgaacccgc gatctcctgc gtgacaggca ggcatgttaa
    19741 cccctacacc acggaaccag ttcattatgg aggttaacgg gatcgaaccg ctgaccctct
    19801 gcttgtaagg cagatgctct cccagctgag ctaaacctcc aacattcaat taaaatgacc
    19861 cgtacgggat tcgaacccgt gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca
    19921 acgggccagg taaatttgct acggagagta agggattcga acccttgaga cagtttggca
    19981 ccatctacat gatttccaat catgctcctt cggcctctcg gacaactctc cagagtgaaa
    20041 gaagctcaat actctttctc aaaatgag
//
LOCUS       DAFTHM010000045        19923 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFTHM010000045 DAFTHM010000000
VERSION     DAFTHM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19923
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.045"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            107..2035
                     /locus_tag="L7C88_001579"
     CDS             107..2035
                     /locus_tag="L7C88_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBP9558402.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            2173..2628
                     /locus_tag="L7C88_001580"
     CDS             2173..2628
                     /locus_tag="L7C88_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBP9558403.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            3098..3367
                     /locus_tag="L7C88_001581"
     CDS             3098..3367
                     /locus_tag="L7C88_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558404.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            3767..4021
                     /locus_tag="L7C88_001582"
     CDS             3767..4021
                     /locus_tag="L7C88_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBP9558405.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(4110..5156)
                     /gene="holA"
                     /locus_tag="L7C88_001583"
     CDS             complement(4110..5156)
                     /gene="holA"
                     /locus_tag="L7C88_001583"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBP9558406.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(5194..7467)
                     /locus_tag="L7C88_001584"
     CDS             complement(5194..7467)
                     /locus_tag="L7C88_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBP9558407.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(7460..7999)
                     /locus_tag="L7C88_001585"
     CDS             complement(7460..7999)
                     /locus_tag="L7C88_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBP9558408.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(8135..8353)
                     /locus_tag="L7C88_001586"
     CDS             complement(8135..8353)
                     /locus_tag="L7C88_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBP9558409.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(8350..8595)
                     /locus_tag="L7C88_001587"
     CDS             complement(8350..8595)
                     /locus_tag="L7C88_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBP9558410.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(8711..9439)
                     /locus_tag="L7C88_001588"
     CDS             complement(8711..9439)
                     /locus_tag="L7C88_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBP9558411.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            complement(9598..10641)
                     /locus_tag="L7C88_001589"
     CDS             complement(9598..10641)
                     /locus_tag="L7C88_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBP9558412.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            complement(10631..11122)
                     /gene="coaD"
                     /locus_tag="L7C88_001590"
     CDS             complement(10631..11122)
                     /gene="coaD"
                     /locus_tag="L7C88_001590"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBP9558413.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            complement(11119..11679)
                     /gene="rsmD"
                     /locus_tag="L7C88_001591"
     CDS             complement(11119..11679)
                     /gene="rsmD"
                     /locus_tag="L7C88_001591"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBP9558414.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            complement(11798..12136)
                     /locus_tag="L7C88_001592"
     CDS             complement(11798..12136)
                     /locus_tag="L7C88_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBP9558415.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            complement(12120..12557)
                     /locus_tag="L7C88_001593"
     CDS             complement(12120..12557)
                     /locus_tag="L7C88_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBP9558416.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            complement(12547..13671)
                     /locus_tag="L7C88_001594"
     CDS             complement(12547..13671)
                     /locus_tag="L7C88_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558417.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            complement(13692..17120)
                     /locus_tag="L7C88_001595"
     CDS             complement(13692..17120)
                     /locus_tag="L7C88_001595"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBP9558418.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            complement(17146..18309)
                     /locus_tag="L7C88_001596"
     CDS             complement(17146..18309)
                     /locus_tag="L7C88_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBP9558419.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            complement(18312..18614)
                     /locus_tag="L7C88_001597"
     CDS             complement(18312..18614)
                     /locus_tag="L7C88_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBP9558420.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            complement(18728..>19923)
                     /locus_tag="L7C88_001598"
     CDS             complement(18728..>19923)
                     /locus_tag="L7C88_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HRDC domain-containing protein"
                     /protein_id="HBP9558421.1"
                     /translation="QTGFERENLRFQVIKDQKKEQYLIEYLKINKNQSGIIYAATRKE
                     VDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRLQLIVATNAFGMGINKSNVR
                     FVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDIQVQKFFIQQSQREEGQKQK
                     EYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNCLDDREIVEVTTEAQMVLSC
                     LKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLMKNQSQKETMQLIEYLISNG
                     YLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQLSDEETDTLFEVLRELRTDL
                     ASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQSKLDKYGEAFLSRIKNADS
                     NVLDK"
BASE COUNT         5769 a         4138 c         3425 g         6591 t
ORIGIN      
        1 agcttaatca ccaaatgata accattatcg ttctcattta gctgttatta ttatcaatta
       61 catttttatt atgctatcct tgttttgaca aggaggtcta ataacgatga ctaatcagaa
      121 aaaagctttt gcagcaacaa tcggctgcct tttatttatg atcttcggtt ttatcttcga
      181 ccgattctct cttaccatca ccccactttt ttatatcagt gccattatca tcggtggata
      241 taaacaaaca tcggaaggct tgaaagaatt gtggaatgat cggacactga atgtggattt
      301 attgatggct ttagctgcta ttggtgcctg tttgatcggt aattactttg aaggagcaat
      361 gttgacattc atcttttgtt taagcggtgc attagaggaa tacacaacta ataaaagtca
      421 aaaagaaatt actgctttga tgaatcttca accacaaaaa gcccaattat taaaagaaaa
      481 tggacaaatg caagaagtag atgtttctca actaaaggtg gataacttgg tatttgtcgc
      541 taaaggagca gctgttccga tagatggctt tttagaaagc acacaggcaa cgatcgatga
      601 gtctgcatta agcggtgaat ctgtgcctgt agaaaaatat ttaggcgatg agatgtatgc
      661 aggaacgctg aatcaaggaa atcccatcac gattcgagta acaaaaacga gttccgaaac
      721 tgtctttgct aagattatcc aattagtaga agaagcgcag aatacgccaa ctcaaacagc
      781 ttcatttatc gaacgaatcg aaaataatta tgtaaaattg attttgcttg ctgttcctct
      841 aatgatcctt ctcccccact ttttcctagg ttggagttgg gatgaaagct tttatcgagg
      901 aatggtatta ttagttgtgg cttctccttg tgcgcttgtc gcatctgcta caccagcttc
      961 tctagctgct ctttcaaatt ctgcaaaaaa tgggatttta atcaaaggcg gtatccattt
     1021 agaaaagctt tctgaattaa aagcgattgc ctttgataaa acaggaacgc tcactaaagg
     1081 aaaaccagtt gtaactgaca gctttttctt tgatgaaaag gatttggcac aacaacttct
     1141 tgttgctatg gaacaaaaaa cgacgcatcc acttgctcat gcgattttgc aatatttcga
     1201 ttgcacaata cctgaagaaa tccaatactt accaatagaa gaaattactg gttttggatt
     1261 acaaactacc tatttaggtg cgcaatggaa agttggcaag cacgcatatg atcctgagac
     1321 gatgataatc agcaaagaga ttgcggaaat gatcgaacgt ttggaaaatc aaggcaaaac
     1381 cgtgatttat ctttctaaag atcagcagtt aattgctgtt ttaggtctgc tagatattcc
     1441 aaaagcaaat acccaacaag taatttccta ctttaaatcc caaaacatcc atacaagtat
     1501 gataaccggc gaccattctg gcacagcaaa ggccattgct gaacaagtag ggattgaaca
     1561 ttactatgca agctgtactc cggaagaaaa aacacaacta gtcaaaaaag agaatgaact
     1621 ttaccaagta aatgcgatgg ttggtgatgg agtcaatgat gcgcctgctt tagcagccgc
     1681 ttctttaggt gtcgctatgg ggcaagggac agatgccgct atggatatcg cagacatcgt
     1741 cttaatgaaa agcgacttaa ataaatttgt ctacagtcat cggctatctt taaaaatgcg
     1801 gcggatcatc aaacaaaata ttattttttc gattcttgtt attctcttgt tgattgcttc
     1861 taacttcctg caatttttaa atctacctct tggagttgta ggacacgaag gaagcacaat
     1921 attggttatt ctgaatggct tgcgtttact aagaccttta cctgatcttt ctgattcttc
     1981 aaaaaaatgt aagtcttgtc cactatacaa agcgcggctg tcttctgtca aataagcaaa
     2041 gtgttttttt atgattttgt ttattttatg aaaaaaacag cttatgaata ggtcttgaag
     2101 gatgaattcc tacttttgta actttctaaa aacatgttat gattgtttcg aagaaagtga
     2161 ggaatatatt tcatggaaag ttggcttttt ttaggaatta ttttacttgt agcaatttta
     2221 gctaaaaatc aaagtctgat gatagcggca gcttttgttt tgattatgaa gctcatacca
     2281 gcctcccgtt cctttttccc ttggcttcaa ggcaaaggaa tcaatattgg ggtgacgatc
     2341 atcacagcgg ctattctaat ccctatcgca acaggagaaa tcggtctacg tgatctatta
     2401 gaagccttta aatcccctat tggctgggta gctgtttttt gcggtgggct agtggctgtc
     2461 ttatcttcca agggtgtagg attgattgct tctgatccac aaatcactgt tgcacttgtt
     2521 ttcggcacga ttttaggtgt tgtcttctta agaggaatcg ccgccggacc ggtcattgct
     2581 tctggtatca cttactgtat cttacaagta tttgctttag gaaaatagaa caaattttgt
     2641 ctattttagg agattcttaa cacccccaat ttactgatcc gtgatatact gacaacgagg
     2701 tgatacaatg ttcgaaaaat taaagtattt cataggaaca atcggctggt ttcttctagc
     2761 ggtacttttg attctgggct tagcttatct attatttcct gatttgatac aaaatgtgtt
     2821 tgatactgct ttttgattga cctattaaaa cgatataggg gatgctcctg cgatgcaggg
     2881 gcttttttta atcaatgttt tgtaataatt taggccgtgc caatgagact tcctatagaa
     2941 ttcgatgctc ttttttcttt ttggctcttc tgctcttttt tgttatacta gattacagtg
     3001 gacaaaagaa agaatgatcg catccacttc aacgaatatc aaaatggaag aattagtgcc
     3061 tgttttcagg ttactttgaa aagaaaggaa gacgcttgtg gaaacttttg aaggtctttt
     3121 aattgatacg tacgttttac aagaacagcc aatgatgctg actgggatca acttgcagct
     3181 tgaggaccgt gtgatcaatg gcctgcttaa agatcgctat ttggcaaaat atatcttacg
     3241 tttgccccta aataaatatg tgctggaagt aagtggcaaa tggaaccgtc ggaaccagtt
     3301 ggtcataaaa aaaatgttga taaaaaatat cgatgaatac attaaaataa tcggtacacc
     3361 agaatagcct ttactgatca aaggatactg gttataaaat aactgcagtt tcttaataga
     3421 aaaacaaaga acaacaggga atcgtatccc ttttcaaaaa aaactttgca aacggttctc
     3481 tttgttatat aataacttag taccaaacat tcccattcaa actttgttta aatagataaa
     3541 taaaaatcta gtttggtttg acgctattgc ctcccacaat agcgtctttt tgattttttt
     3601 cagcttgtac tatccgtttt tactgaaaaa aaatcctaat aaaagactgt taaggaaaaa
     3661 aacttgtcat gttcatattg caaagcacgc tgcctttagg tataataatg aatgttgaat
     3721 tatgcggtaa cacgcgtaag aacttaagtt atcggaggtg aaactaatgc caaacattga
     3781 atctgcaatc aaacgtgttc gtacaagcga aaacgctaat gtgaaaaatt catctcaaac
     3841 aagcgctatg cgtactgcaa tcaaaaaatt tgaagatgct gtagcttcag gtgctgacaa
     3901 cgtagatgcg ttatataaag aagctgttaa agctattgat atggctgaat caaaaggtct
     3961 aatccacaaa aacaaagcta accgcgacaa atctcgttta agcaaaaaaa tcgctaaata
     4021 aaagaatcgg cttcggccga tttttttatt tgtcaaaaaa aggacaaaaa caaacgacct
     4081 tcccgcatgc tttgccctcg tctttcttct tatcgatttc ttaacaactg ccctgtgcgc
     4141 aaaacgaata gttgaaaact taattctttt tcgatttgtc ccgttttgat ttgataatcc
     4201 atctcaacta attgatcaaa caactgtacc agcaaatgtt catcgaattt ttttacttcc
     4261 tgcatggcaa gttttacacg atatggatgg attttcaatg tttcagcaat atttgcctgc
     4321 tgataaccaa tctttacaag aaattttgtc tgtaaaaata aacgtaattg agaaagcaaa
     4381 atcgcattaa ttttgattgt ttcttcccct tgcataacta aatcttcgta taaacgcaaa
     4441 gcttgttccg tcttcccttt taaaatatat tgggtcatgt caaaaatatt atgttctaac
     4501 gttttaggaa ctaattcttc tacttctctt accgtgattt gctgttgatt ttgtccataa
     4561 aggaccaatt tctgtaactc tctcatcatt ttggataaat ctaagtcggt caacctcaag
     4621 aataaatcaa ttgcacttcg ttccattttg attgaggaat tctctaaggt attcatcaga
     4681 tattgacgta cttctttttc attcaactgt tggacattga tgataattgc tgtttttttc
     4741 aattgtttcg ttactttttt ccgttcatcc aacttttcat atggcgcaaa gaatactaat
     4801 acagtcgatt ctaatggttc tttcaaataa gccgtcaata aatcagtatt ttgttcgatt
     4861 ccattgttta ctttttcacc tgttaaaaaa taaggattct ctacgaatac taaccgttga
     4921 tctccgaaaa acggcaacgt ctctgcttca gctactacct catctaaact tgcattttcc
     4981 atgtcaaaac ttaaaaaatt taagtcatct tcgccctcta attggatttt tttgacaatt
     5041 tctgtccgaa cttgatcttg gagaaacttt tctgttccta aaatcaagta acaagatgca
     5101 agtttttctt tacgtatttt ttgtaactct gcttgtatac tcaaattact caccactttc
     5161 aaaaattatc ctaccatgag cagatgagaa ttactagtct atcattgttt ccactagccc
     5221 atgaggatga aaaactggat gccagcgata ggtgatcatt ccttgttgat ccgttcgcca
     5281 tgtttttatc tgattttctt ctagtgtctc caatacttcg ctgtgcgggt gaccataacg
     5341 attatttacg ccgcaggata taatcccatg ttttgcttca atatgggaaa gaaaatctgt
     5401 gttacttgac gtacggctac cgtgatgacc taatttgact acatcggctt tcagattagg
     5461 ataaatcaaa agcaattgtt tttccattgc ttgattcaaa tctcctaaaa ataaaaagcg
     5521 cctattgtta tattccatcc atagaccaat cgaatcttca tttcttccct ctcccttttc
     5581 aaaaggagtc aatacataaa gatcataata accgctgatc ctgtccccat gtttgatttc
     5641 aatgatctca gtaccatttt tttgagcttc agataaatgc ctttgtaatg gctcatttcg
     5701 tccagcgccc caaccgatat aaattttttt gatagtaaaa tgctgagata acgtgggtaa
     5761 ttctcccaca tgatccgtat cgtcgtgtgt caagatgagt ttatcgatta cacttatccc
     5821 ctgacctttt agatatggaa cgatatttct ttcagcagga ggacgtatca taccttgcgc
     5881 ccacttttct ctttcaaagt gtaactgacc tccagtatcg atcaaaatcg tttcttttcg
     5941 aaaaggactt tgcaaaaaga tactgtctcc ttgaccgaca tcgataaaag cgatcgttga
     6001 agaaaagcgt aaaaatggca aagtcaaaaa aataaaagaa aaaagaccaa cataaaacaa
     6061 gtgtttcaca ggttgttctt tcaacctatc catacaaatc agtaatccga aaatatacat
     6121 cccagatagc acaaggggca aacgtcctat aatgagagac gaccctgaag aaaaatcgat
     6181 tattcgctca aataagatta atccctcttc tatcagcaaa agtaaagttt ccggcagcca
     6241 gcgattgaag agtgtgagaa ataacacacc aggaagaaaa agaaacttga ataccggtgc
     6301 aatcagtaat gtaaaaagac tacctaaaat aggccactca taaaaatgcc atacaatcaa
     6361 cggcatcgtg atcatagtaa acaggacgtg agaggccgtt tttttcaacc aatctccatc
     6421 aaaagaaatc aggataaaca aaaaactcat gaaaaaacta agctgtccac ccgcatgaaa
     6481 aagaaatcga ggatcaaata gtaaaagaag ccaaaagaca actgcaaata agtccatggt
     6541 ggaataatgc ttattcagca atttgactag caatcgcaat aaaaacagca aactagcacg
     6601 caaaacagaa atagaacttc ctgcaataga aacataacag atagttagta gactcaacgg
     6661 aataatactg acgtgtagtg gccatccgat acgtcgaaat aaataataca gccaccctaa
     6721 ataaaattgg atgtgtagac ccgatagact gaacagatgc agcaaaccac tctccctaaa
     6781 aatttcttct ggttctctga atcctgcatc tttatagccc cataataaag aattaatata
     6841 tacacttgtt ttttgcggaa attcagattg gacaaaggag ataaaagatc ctctttttct
     6901 ctgaagccag tttcgccagt gattttgcat ggtgatctgt tcaatctttt gaatttggaa
     6961 ccgtccagaa attctatggt tcctgaagta agcttcttgg tcaaaattat aaagattccg
     7021 cttttttgct ggagagatga actcgccttc agcagtcaat tctattccct ttcctcggaa
     7081 gttaagccat gttttcaatt ctgcttctgt gtttacttga taagaaagct ggagcttttg
     7141 tttattctct gataaccttc cttccattgt caaaaaatta ccatttgcac gaatcgtatc
     7201 tgtaaataca gtaatttgcg cagatgttgt tttttcctct aaaaatgaat actcttgtag
     7261 cctataagaa atggataccg ttatgctaca caaaatacac aagtacgcga taaaacgtcc
     7321 ttcttttagc gaaaaccata aaaaaattcc ggcaagaagc aaacgataac cccaattgtc
     7381 agtgtaatac aacaaacaga taatcatcga cgtaattgcc ggaaaaatca accgatttcg
     7441 aacatgcctt tctaaaacgc tagacatgtt ttcctgttaa ttcattttga agttttgaaa
     7501 aatgctgtga gtctaaagca acttggtgta cagatacacc taattgttcg atcaacgctt
     7561 gggcataagg atcatttcga tagtcatgga gataattgat ccctttcaca ccagcttgca
     7621 acaaagcctt tgtacaggcc aaacatggaa aatgtgtgac atagatttct gaaccttccg
     7681 tcgggatacc aagttttgca cactgtagga gtgcattcat ctctgcatgg atcgttcgca
     7741 agcagtgtcc atccacgacg taacaccctt catctatgca gtggacatct ccactgactg
     7801 ctccattata gccgccagca atgatccttt tttctcgaac gagtgtcgct cctacttcta
     7861 aacgtgtaca cgtactacgt aaagataaca gtactgcctg agccataaag tactggtccc
     7921 aaggaatgcg ttcattatgt gacttatcag taactttttc tttattcgta tcgcatgctt
     7981 ttgaagattt ttctaacatg ttttatattc ctccgttttt tcaagttgat taaaaagtac
     8041 tcattgctta aacaaaatat tctttaaata taacgaatca tcctgtctga caaaagatcc
     8101 tacccttcac tgccgaaatg aagtccgtca tccattagcc cattataaaa attcttcgaa
     8161 tccatttgtt caagaaattc cgtataaaaa tcgatacttc acaatcatgg cgttttgcta
     8221 cttctgtgag aacagagata tattctttga tcaacttgtt attccgatat ttttgttttg
     8281 tctcatcgac tgctggtggc gtgataaaga aagcatgatc agaactatag tcttttttca
     8341 gctgaactat catccactgc agattttttg gtacgtttct ttagaaagtt gtttatgctc
     8401 tgctagatca ttcgtcccaa tgagaataaa tactttatct gctgtatagc taagtacatc
     8461 tttggcaaag cgttctcgta gagcttgact gttattgccg ctgacagccg tattcataat
     8521 atgaatccca gatattttat tttggagata gacattcagc attggttttt ttaatgtttc
     8581 tttgcgaaca atcaagctat ttcctatcca aaaatactac ctcctcgtcc tgccaagctc
     8641 ttagaattgg attattctta gtatccatta gcgtccattt attgctcgtg ccagtcgatt
     8701 ttgaatcatt ctatttaatt gtaacgaagt tttttagttt ttcaactgtc ttttcaccga
     8761 taccagaaat ctcctgcagg tcttccactt tctggaagga tccgttttct tctctaaatc
     8821 gaatgatttc ttgcgctttg actgatccga tcccaggaat ctgctgaagt tctgatggag
     8881 tggctgtatt gatatttatt ttgggaggct cggaatctgc tgtaggctgt tttccttccg
     8941 aggatgccaa ctgatcaaga tgttctggca gctcttcacc tacagcaggg atatatagga
     9001 cttgctgatc ttctatcttc gcagaaaagt tgattcgatc gctatccgct tcttctaata
     9061 atccacctgc acgctttagt acatcataga cccgttcttc tgaagaaaag gaatagatac
     9121 caggctcctt cacacttcct ttgatatcgg tgtacatgac ctttggacga gcatcctctt
     9181 ctacatcgtt tccttcagct gatggatctt ctccactgga actaaacgaa gaaagtattt
     9241 cttttgcagc agtctcttct gtttctctat aaaatagcaa atttgataat aaaaaaccac
     9301 ttgcgataca aaagataaga actatcatag acatccaaat gatcaatttg ggtgaagcta
     9361 gtattttctt gctgattttt tctatcattg ttcttttttc aaagaatgac cagtaaaaat
     9421 cattcattac tcctttcatt taaaattgaa gaaacagtga gctctggcaa aatcgtccct
     9481 tcaacatcta attacgtcaa ttttttcttt tgtttttatt tttatcgtga agatttttga
     9541 cgaaaaagag gggttgtgac agaactcgtg tcacaacccc tctttaatta tttagtttca
     9601 tttcattttc tctagatagt caagcgcttc ttgtactgtt tttactggta cgattttcat
     9661 tgaggaattc aattttttag cggcagcttt tgcttcttcg tagttggttt ttatttcagg
     9721 atattctttc ttaacatcgt ctgaaatcgt atcatctggt gcaaagaaaa tctctacgcc
     9781 agctttatcc gcacttgcca cttttttatc gattcctccg attcggccaa cttctccttc
     9841 actgttgatc gttccagttc ctgcaatttg cttaccatgt cgcaagtttt taccagtgac
     9901 ttgttcatag atttctaaag tgaacatcaa tcccgctgat ggcccaccga tagagccaga
     9961 attaatacga acatctgtat ctgattcgat ctcggtatgg tcagtaagcg tgatacctat
    10021 tcctgccttt ttatctgttg gtaactcgat cagatcacca gaagctgttt tttcttcacc
    10081 attatgcaaa taactgattt cgattgtttg tccaactttt tggcttttta cataatccat
    10141 aaatgcttct gtactttgaa agcttttccc gtctactttt gttactgtat ctccaactga
    10201 aagcttgcca aagaaattcg atgttttctc tacactcatg acatatacgc ctttgaattc
    10261 cattttataa ggcttgtctg caagttttaa cgcttgttcg attgctgcat tttgggaaga
    10321 atccatataa tactgttgca tttgattata ttcttcattt gtcgccccac cagtcaattc
    10381 ttcttcactg atcaattctt caaaaggggt cattttagct tttaaagcta agaaacctgt
    10441 agcttgcctg ataccaacag aggtaagaga gaaagaccca gaacctttat cttccttatc
    10501 attgaccgta attagttctt tcagatcgat cgtggctccc ggtgattcta cataatacgg
    10561 caagggaact actacaaatc caatgatcaa cattccaaat atgataatca gtactgtttt
    10621 caaccattgt ttagctttca tttgattcac gctttccagc taaagcttcg ttgatcactg
    10681 gcggtaagta gctgctcaca tctccgccaa agtgcagtac ttcttttaaa atactggaac
    10741 tcacgtgact atattctggt tttgctaata agaagacagt ttccaattca tcatatagat
    10801 gatgattcat ctgagcaatc tctcgttcat attcaaagtc tttgatactt cgtatgcctc
    10861 tgatcaacgc atctgcacca atctcttttg ctgtttctac cgtcaattga ttttcttgat
    10921 gcatgacttt tacattagga agatgagaaa cagcttttgt gatcaatgtc attctttctt
    10981 ctgggggaaa caaacttttc tttgaagtat tgataaaaac accaattact acctcatcga
    11041 ataatttagc cgcacgttcc accgtatcta agtgaccttt tgtaaaagga tcaaaacttc
    11101 ctgggaataa tgcacgtttc attgatttcc ctcttttcta tagatagtta cggccgttat
    11161 gccataaatc tgttttctta tttgatggaa tccagccaca gtttctggca attcgactgt
    11221 tttatccgtt tcgcatacga taactgcggt tttagaaaaa agtcccagtt cttccatttt
    11281 atggatttga tcgattattt tttgttttgc atatggcgga tcaagaaaca agtagtcgaa
    11341 ttgttgtttc tccgctgcta gccgttcgat tgctttgtcc gcatcaagtt ttattgtggt
    11401 aaatttctct ggttctttcg taatttcgat gttttctttg atgattttta gcgcttggta
    11461 atttttgtct acgcataccg catgactgca gcctctagat actgcttcga tagctaaacc
    11521 accgcttcct gcaaacagat ccaatactgt ctctccatca aaatatggtc caatcatatt
    11581 gaatatggat tcttttactt tatctgtagt tggtctggtg ttcgcccctg ctaaactttt
    11641 taaacggcgc ccgccataat ttcctgatat tatccgcatc tactcactcc ttagaaatgg
    11701 tactggtact agtataccaa aaaaatactt ggacaatgat caaaaatcga tcgttatcca
    11761 agttattttt tatttaaaaa ctgctcataa gagattttta aagatgttca gctaatcgga
    11821 tttctgtatt tagctcttca atttcgaaac cttcgtcttt taatactgtt ttgtttccta
    11881 ttttttcggc aaaattcatt tcgatatccg gtcggtaaga acgttctacg tttcgaacaa
    11941 aatgtaattt acggattcgt tcttctgttt cttccaatgt ctcttcattt aagtaaagca
    12001 cgacatattt cattcttctt gagacataat gcaacaagcc gaactttttc agattcttta
    12061 attgttttaa gctgtagacc catacgatca gcccgcgtcg ttttgttatt tcaaattcac
    12121 tattgtctaa ttgcatgaca attacctccg catccaaagt gttttttcgt ttcaaaaaac
    12181 gggctacctg catctacttt gatttcatta gaaacttctt cggcaagtac ttggacaatt
    12241 tgatccaaca gactttgcag ctgtgtttca ctatatcgga aagctgcaac atgctcatcc
    12301 atatcaagct gtctttttgc ttttcgaaca gctcgttttt tttcacgata atcaggtgca
    12361 tactcaccat atgccgctac attttcaaat gcttctttct tagacaagaa cgcttctttc
    12421 aactggcaaa cttttgcaga ttcttccatt gactgtttat gttcaagata agaagccatc
    12481 gttttactct tttttatcat ttcagcgact tggaggcatt gatcctccag ttgaaacagc
    12541 tcttcgttaa cgatcactgc tatcactact ttctccgttt tcttcttgca ataagactaa
    12601 catattttct ttagaaaaag caatgcctac agaatccgtt cccgggtcca tgaaacggtc
    12661 atggttgtaa ggatcgctgt accaatataa aaacgaaaaa gtagcgtcaa tcgccggatg
    12721 aataaatagc ccactagtat tttctaattt ttgtttactg attaacttct ccaattcatc
    12781 attcgtcagt gagaatttca ctgtcgtttg agcactgcct agcgattttt gccaatcagc
    12841 catacgttcc tctgacaata tttcctcagg ccttgtcaaa aaatcatgta gtagcagctg
    12901 actgtggttt tgaaaggcaa gtgtttgatt gtatatggga agttcgtctt ctcttctaag
    12961 catatttaat aaagtcgtac tttttcgttc tttaacgcga ttgattgatt cccaatcagc
    13021 cgatttatct gcttgataat gtggaaggcc ttcaccaaac acttgatatg gcaatagttt
    13081 caaaagacta tctttatcta aatacacaac tgaaaatagg ccgtttgttg tttgatcaaa
    13141 aaataaaata gcaaaagtgt cgttatcaaa agcaattagc ggacgataat tcatatcctc
    13201 ttccattagt tcgattccaa cttctgtatc atggtactca aaagtgaaat tagtatagat
    13261 agtagtgatt ttcgtaagat cttgcatcgt catccctaaa taaaacggcg cgatatcagc
    13321 aggccctgtt tgcagtactt taacagttgt gactctgctg tcttggatgt tcgcttcaaa
    13381 tgtgagatga ctagctttat tttcataata tcttgtttca aaaccaaatc cgctagttaa
    13441 tcgatcatag gcttggccaa aatccttttc cagctgatcg atcggttttc cgatataagt
    13501 agaaaaacca gttgctttaa gctcctggta tttccacgtt gtcatttggt ttgatatttg
    13561 ttgatcagag ttttccttca cttcaagttt tggcggaaac aagactggtt ccatgtagaa
    13621 tgccacaata actaatagca gaatcagcca aaacaaaccc agtcttttca tgtttcccca
    13681 cctttcgctt attatttctc agtcacttca atcaaaaggt caccagacga aatagtgtct
    13741 cctgaagaca catatacatg tgcgacttct ccgtcaaaac gtgcttcgat ggccgtttcc
    13801 attttcatcg cttcagtaat catcaacgta tcaccttttt taacgttatc gccttttttc
    13861 actaatacat ccaaaacaga accagacatc gttgctccaa tttgttctcg gtttgtcggt
    13921 tcagctttca atcgggtttg gaccgtactg atgatcgaat tatctttgat agtgatttca
    13981 cgtctttgtc cattcaaatt gaagaacagt acgcgattcc cttcgatatc gggttctccg
    14041 atttcatcta aacgaatgat aagcgttttt ccgcgttcga tttgtacatt gattgtttca
    14101 cccaaacgta taccttggaa aaatgttggt gtgtccagta atgtaacatc gccaaattga
    14161 ttatatgctt tttgatagtc caaaaagact tgcggataca tcaaatagct taatacttcg
    14221 tcttgttttg gttcatagcc aattttttct gccaattctt tttttacttc gttgaagtcg
    14281 actgattcag ccaaaagacc tggacgttca ttcaatgcag gtctgccttt aagaataatc
    14341 ttttgcaatt ttttaggaaa tccgccaacg ggttgcccta gttctccttg gaagaaagtc
    14401 acaacagatt cagggaaact tagtgtttcg cctttttcat aaatatcttc ttctgtaaga
    14461 tcattttgga ccataaatag tgccatatct ccaactactt tagatgatgg agttacttta
    14521 acgatatcgc caaacatcaa gttgacagta tgatacattt gtttgatttc atcccagcga
    14581 tgacctaatc cgacagcttt tgcctgttgc tgtagattcg aatactgtcc tcctggcatt
    14641 tcatgcatat atacttctgt ttcaggagca ttcaagccgt tttcaaacgg tttgtaatac
    14701 atgcgcacat cttcccaata atggtttaat ttctgtgcat tttcaatcgt gatttctggc
    14761 agccgtggac cattgaccag tgcataatac aagctgctca tgctaggctg actagtattc
    14821 ccactcattg cactcattgc cacgtcaacg atgtctactc ctgcttttga agcagcagaa
    14881 taagtgatga ttccattccc gctggtatca tgagtatgca gatggattgg cagatctgtc
    14941 gtttctttca attcactaat caaacgataa gctgcctgcg gtttaagcag cccagccata
    15001 tctttgattg caatgatatg cgcacccagt tgttctagtt cctttgccat gtctttataa
    15061 tactgaacat tgtattttgc ccgacttgga tcgttgatat cgccagtata gcaaatagct
    15121 gcctctgcga ttttaccagt atcccgtaca gcttggatac ttttttccat ttgtggagtc
    15181 cagttcaaac tatcaaagat tcgaaataca tcgattcctt gcgctgctgc ttctttgaca
    15241 aattccacca atacattgtc aggataatta gaatacccaa cggcatttga acctctgaaa
    15301 agcatttgca gcaacgtatt aggcattaaa gaacgaattt ttctcaaccg ttgccaagga
    15361 tcttcattca aaaagcggta agccacatca aatgttgctc ccccccacat ctcacttgaa
    15421 aagagttcag gaagaccttc tccagtcaaa cgtgcaatct gcttgaaatc ctttgtccga
    15481 acacgagttg ctagcagact ttgatgggcg tctctaaatg tcgtatccgt caacaacaaa
    15541 ttttcctgtc ctttgatcca ttcgaccaaa gcatcggcac ccttcgcatc taatacattc
    15601 ttagccgtta cgtaatcagt tcttgtgatt agatctttag gcatacgtgg ttcttcataa
    15661 aatggttttt cgccactttc gatacctgga aaaccattca cagtaatttc accgatatat
    15721 ttcatcgttt tgtttccgcg gtctcgtagt cgaggaaatt caaataatgt tgctgtacta
    15781 tcaatgaagg ttgtttttgc atttcctgat tggaattcag gatgtgtgat gacattgagc
    15841 ataaatggaa tgtttgtttt cactccacgg attctaaatt ctttcaagca acgttccatt
    15901 ttctgaatgg ctgtttcaaa ggtagcacca tgcgtacata cttttactag caatgaatca
    15961 aaatacggtg tcactacata gcccgcgtaa gcatttccga catccagacg tacgccaaaa
    16021 ccaccaggtg aacgatacgt atcgattttc cctgtgtctg gtaaaaagtt attcaacggg
    16081 tcttctgtag tgattcggca ttgaatggct gaaccattta atttaattcc ttcttgctga
    16141 ggcaatccga tttctttatg cagatccaaa ccttgagcaa tcaacagttg cgttgttacg
    16201 atatcaatat ctgtaatcat ttctgtgatc gtatgttcca cttggacgcg agggttgact
    16261 tcgataaagt aaaaatcatc tccttcaaca agaaattcta ctgtacctgc gttgacatac
    16321 ccgacatatt tcatcaattg gacagctgcc tggcagattt tttgacgttg ctgttcattc
    16381 atagagacac aaggcgctac ttctactact ttttggtgac ggcgctgaac agaacaatct
    16441 ctttcaaaaa gatggatgac gtttccatgc gtatccccga gaatctgtac ttcgatatgc
    16501 ttaggattag cgatgtattt ttcaacatac acttcatcac taccaaaggc tgcttttgct
    16561 tcgcttttcg cacgttcgta gccctctctt gcactctttt catcgtgagc tacacgcatg
    16621 ccgcgtccgc cgccgcctag agctgccttg atcataatcg gataaccgta ttgtttcgca
    16681 aactccaagg catcgtctat agaagcgatt ggtccatctg tgcctggaat cgaagcaatc
    16741 cccgcttcga tagctgcagc ttttgctttg attttatctc caaaaatatc taaatgatgc
    16801 agtttgggtc caacaaaaat gatgccttct tcttcgcacc gttgcgcaaa attcaagttt
    16861 tccgacaaaa gaccgtaacc cggatgaata gcgtcagctc cgcattcttt cgcgatagaa
    16921 atgatccctt caatatctag atacgcatca atcggttttt ttccttgtcc tactaaatat
    16981 gcttcatccg ctttgaaacg gtgtacggaa tattcatctt cttctgcata gattccaaca
    17041 gttttaattc ctaattctgt acaagcacga aatacacgta cagcgatttc acccctgtta
    17101 gcaactaaaa cttttttcat cgaaccactc ctacatcttt ttttattata aacctaagct
    17161 cttgcgtttt tcatccgcac tgatgttgag gacaaagccg acacaaatcg aaagcatcag
    17221 caaactggag cctccttgac ttaaaaatgg gaacgtgatc cctgtcaaag gaataacgcc
    17281 agtaattcct ccaagattga caaatacttg gatcaaaaac attgcgccga tcccaatgca
    17341 caaaagcgaa ttgaacggat cttttgaacg gatacctaca aggacaatgc gcacaatcat
    17401 aaagaatagc aacgctaata tcaaaatccc cataatcact cccagttctt ccactacgat
    17461 tgcataaata aaatcggttt gtgcttcttg taaaaatcct tttttctgga tactgttacc
    17521 taatcccctg ccaaatagtc ctccgttgaa catggcatag tagccgttga ctagttgatg
    17581 ccctttattt aattcgtctg agaaaggatt ttggtaaata gcaaatcgat tatagatata
    17641 ctgtaaacgt ccgggtaaga tctttccgtt tgtgatattg atcagccaga tcgtaaaagt
    17701 acttagacaa aagcctccta ctcctacaat caaagtatac acataattga ctccgctggc
    17761 taaaagcaga accaaaataa tcaaaaagat aactgccgca ttaccaaaat cgggaagaat
    17821 agcgactaat gcagtaagtc cgataaccat tgcaagtgga cgtttcacag tcccaagaaa
    17881 atctttttgt acactgtttt gtcttttaga taaagtcaga gacaggtacc agatagaaat
    17941 gatttttagg tattcggcag gttggatcga gaatcctgca atttgcagcc aacctttcgc
    18001 cccattgatc tccttaccaa aaaacacaac aatcagcagc aaaatcgtca aaactgcgat
    18061 ggctgccatg atcaaacgct ggtttttcaa aacatctgtt ttcattttat aaagtagtgc
    18121 gatagcaatc aagctaagca cccaaaaaat actctggtta atgactgatg cggacggatt
    18181 ttgtccgttt tctaataata gatacgacgt agaactatat accatgatca atcccaatac
    18241 acataaaatt aaatagggaa tcaagatgct atagtctaat agatgccttt ttttcacttt
    18301 cttaggcaag tctattcctc cttgccaact tcttttttat cataaatttc ttggtaaacc
    18361 tcactatata actgattcaa ttctcgttct agctcactta acatcagctg gccctcgttc
    18421 tttccgatta ctcctatacg gacagcaaaa ccgacttgcc gggaaaagcc gtacatctgt
    18481 gtatctacca cttcttcgaa ggctttgcat tgtgagatac agagactgtt gttttgattt
    18541 cggattaatc gtttgatccg ttctgcttca tcatttaata cttggatcgc aagttttttc
    18601 gacaaagaat ccatctgtgc ttacctccca ttctaattcc ttaattataa catatttgat
    18661 tttcataagg agcaaaaaaa acagatttaa ccagttgttt ttattcattt ttacgtattc
    18721 gttctttcta cttatccaga acgttagagt ccgcattttt tatccgagat aaaaaggctt
    18781 cgccatattt atcaagcttg ctttggccaa ctccttttat ctgaagcatc tccaatctgc
    18841 ttgatggacg tattcggctc atttctttca atgtggaatc tgaaaatacg acatacgggg
    18901 gaacgcctgc ttctgatgct agatccgttc gcagttcccg cagcacttca aatagtgtat
    18961 cggtttcttc atccgatagc tgctggactt tcttgggttc ctttcgataa acagattctt
    19021 gtcctttcaa tacttgtatc cctctttctg ttactttcaa aacaggatac tcaccattga
    19081 tggtcagaag atagccattc gatatcaaat attcaattaa ctgcatcgtt tctttttgcg
    19141 attggttttt catcagtcca taggtagata aatgtccaaa acctaaagct tgcagctttt
    19201 gttctttcga tcctgctaag actttcatca gcatttgttt accatagttc tcacccatac
    19261 gttttaagca agaaagaacc atctgtgctt ctgtcgttac ttctactatt tctctgtcat
    19321 ctaaacagtt accacaacgg ttgcacggac tgcttgtctc gccaaaatag tttaggatgt
    19381 attgctgaag acaggactca atatacacgt attctgtcat cgcttttaat ttttcatatt
    19441 ctttttgctt ttgcccttct tctctttggg actgctggat aaaaaacttt tggacttgga
    19501 tatcttgagg agagaaaagc aggatggctt cactggaaag accatctctt cccgcccgac
    19561 cagcttcctg atagtatgct tctagagagc caggaatttg ataatggata acaaaacgga
    19621 cattgctttt atttataccc ataccaaatg catttgtcgc tacaatcagc tgcaagcgat
    19681 cgtataaaaa ggcttcttgc atttctgttc gctcattctc atttagacca ccatgatatc
    19741 tacccacgga aaaatcgaat tttttaagca aatgatagag acggtctact tcttttctcg
    19801 ttgctgcata aatgatacca gattgatttt tgttgatctt taaatattcg attagatatt
    19861 gttctttttt ttgatcttta attacttgaa atcgtagatt ttctcgttca aaaccagtct
    19921 gaa
//
LOCUS       DAFTHM010000046        19458 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFTHM010000046 DAFTHM010000000
VERSION     DAFTHM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.046"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..1031)
                     /locus_tag="L7C88_001599"
     CDS             complement(<1..1031)
                     /locus_tag="L7C88_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9558422.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLY"
     gene            complement(1045..1969)
                     /locus_tag="L7C88_001600"
                     /pseudo
     CDS             complement(1045..1969)
                     /locus_tag="L7C88_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            2086..3165
                     /locus_tag="L7C88_001601"
     CDS             2086..3165
                     /locus_tag="L7C88_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBP9558423.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            3197..3790
                     /locus_tag="L7C88_001602"
     CDS             3197..3790
                     /locus_tag="L7C88_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9558424.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(3900..4127)
                     /locus_tag="L7C88_001603"
     CDS             complement(3900..4127)
                     /locus_tag="L7C88_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBP9558425.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(4230..6818)
                     /locus_tag="L7C88_001604"
     CDS             complement(4230..6818)
                     /locus_tag="L7C88_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBP9558426.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(6838..7497)
                     /locus_tag="L7C88_001605"
     CDS             complement(6838..7497)
                     /locus_tag="L7C88_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBP9558427.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(7546..8049)
                     /gene="trmL"
                     /locus_tag="L7C88_001606"
     CDS             complement(7546..8049)
                     /gene="trmL"
                     /locus_tag="L7C88_001606"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBP9558428.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(8270..9136)
                     /locus_tag="L7C88_001607"
     CDS             complement(8270..9136)
                     /locus_tag="L7C88_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBP9558429.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            9245..9886
                     /locus_tag="L7C88_001608"
     CDS             9245..9886
                     /locus_tag="L7C88_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBP9558430.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(9948..11309)
                     /gene="mgtE"
                     /locus_tag="L7C88_001609"
     CDS             complement(9948..11309)
                     /gene="mgtE"
                     /locus_tag="L7C88_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBP9558431.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(11327..12226)
                     /locus_tag="L7C88_001610"
     CDS             complement(11327..12226)
                     /locus_tag="L7C88_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBP9558432.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(12228..13025)
                     /locus_tag="L7C88_001611"
     CDS             complement(12228..13025)
                     /locus_tag="L7C88_001611"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBP9558433.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(13003..13707)
                     /locus_tag="L7C88_001612"
     CDS             complement(13003..13707)
                     /locus_tag="L7C88_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBP9558434.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            13838..14413
                     /locus_tag="L7C88_001613"
     CDS             13838..14413
                     /locus_tag="L7C88_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBP9558435.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            14531..15208
                     /locus_tag="L7C88_001614"
     CDS             14531..15208
                     /locus_tag="L7C88_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBP9558436.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(15287..17095)
                     /gene="pepF"
                     /locus_tag="L7C88_001615"
     CDS             complement(15287..17095)
                     /gene="pepF"
                     /locus_tag="L7C88_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBP9558437.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(17271..18269)
                     /locus_tag="L7C88_001616"
     CDS             complement(17271..18269)
                     /locus_tag="L7C88_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBP9558438.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(18495..19148)
                     /locus_tag="L7C88_001617"
     CDS             complement(18495..19148)
                     /locus_tag="L7C88_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBP9558439.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT         5651 a         4217 c         3365 g         6225 t
ORIGIN      
        1 aaataaagtt tatacaaact ttcgctgatc aagttgacga gatttaattg accaacaatc
       61 ggaatatgaa gatcaatcca atacttcact tgttccgacc ccatcatacc agcaaaaaag
      121 ctcatcgcaa tcgtcactga aatcaagatg ctatcctttt gcaccagatt catttttggt
      181 atcaaattac caaccaatgt acctaacaaa atcgcacaca acgaccccag agcggtaaca
      241 atcatcaacc attgccaacg ttcaccaaag tctacttgat agataaaacg aaagacagct
      301 aacataatat aaatctctgt caaaacaatc gtaaagcttg ctgccaaatt agcgattgaa
      361 actaacgatt gctttctagg aatcaaggac aagcgaatac catttgacga ttgatttgct
      421 tgctgatcct gtacattgcg gaccccccac atcgtcccgt agagaatcgc cattccaatc
      481 agagtgaaga aataaaaact tttgaaactc atattacgac ctgcatgaac ttcttgaaaa
      541 gatacttctt gttcaaaaac agtcatgatg ggcgcgagat caacgttctc cacttctgcc
      601 actttactcg aaattatacc aatacgctgt aaaaattgat ccatgacgtt tttcatcaac
      661 gtctgactca ttcctgcttg acccacatgg agcgaaacag atgaaccatc aatgagataa
      721 aaaccagcca aatcatctgc atttagcttt tcattcgctt ctacttccga tagttcctgt
      781 acttcaaata atggtttatc attgacttcg acttgttcta agactgtggt aaaattttcc
      841 gaaagcgctg tttgatccgc tttgattaca attccagtat taatcgtttc gagattgcca
      901 ccttgatcaa tctcgccaaa ggccgccata aacatcaatc ctaaaagaat tggaaaggcc
      961 aatgtccaaa acaacatgga tttatttcgc agcagtattt ttgtgcgata tttataaaaa
     1021 tgccaaaaca ttatttcccc tcctctagtc tctcaaatcc ttgccagtaa tctctaaaaa
     1081 gacatcattc aaggacgctt ctttggttgc tatttttccg taactgatct tttcttcttg
     1141 taagattgta agaatcggca acaatactgt atttagttca gtagttgtta cttggagctg
     1201 acctttttta taagcgattc catcagaagc tattgttcgc tgacaacacg ttttctggga
     1261 gtaatgggat gtcgatcgtc aaacgatccg ccgtccgtac catatctttt agagattctt
     1321 tggttccttt agcaatcacc tgtccttgat ccatgatcac gatctggtcg caaagaattt
     1381 ctacttcttc catgtaatgt gttgtataga caatggttgc tccttgtcga ttcagctcct
     1441 tgatactttc taaaatttta ttccgacttt gggggtctac agctactgtc ggctcatcta
     1501 aaaaaattaa ccgcggcttg tgggcaatcc cacatgcgat gttcaaccga cgtttcaagc
     1561 caccactaag ttctcctgga cgaaacgaaa catatttttc taatcccact aattgaatca
     1621 cctcttcaat caaggctttc cttttctctt tttcggaaac atataaaccg caaaaataat
     1681 cgatattttc ttgcacactt agttcgtcaa agaccgcaac gtcttgagga acgaccccaa
     1741 tcattgcctt gacagcataa ttttcaggag tcattgttgt cccgaacaat ttaatggttc
     1801 ctttgtcata atttaacaaa gaaagcatac agttgatggc agtcgatttc ccactgccgt
     1861 ttggtcctaa cagacctaag acttctcctt cttgtacttg cagatcaaaa tgattcaatg
     1921 ctacaaaatc tccatagcgt ttgactaatt tatcaatttc gataatcatc atgaaaaact
     1981 ccttccaaat ttcttgttga tctgactata ataaagtgca agaaaagaaa ctagtgacga
     2041 ttggctaaac cacacatgac atttgtcaca atgaaggagt ctgctatgca taaatctcgg
     2101 ctactcaacg aaactagctt tctactggtt atctcattgc ttttgctggt aagtcaagga
     2161 ttcgttgcta tgcaagttat ctatttattg atcgccgttt tattcactgg tgtcagttat
     2221 ttactgccta caaagccaaa ttggattttc caagttattc tatttctttt atgtgccttt
     2281 ttacctgatc ttgtcctgtt tctgccagcg acgatgcgag tgatcgcccc tgaagaaagc
     2341 caccttgatt acttgttttt gttaggtttt ttgttgattt cgacggttgg taatcatccc
     2401 cccatcaagg tcgcctttgt cgtaattttg ctgttttttt ccttttactt acgaaaaaaa
     2461 gatcaacgaa cgaccgatct tgagaaaaag tacattgtct ccaaagatac tcattgggaa
     2521 aaacaacaag agttatcgga acaaaataaa gcattggccc tgtcacaaga aacacaatta
     2581 gccttgcaaa ttgtggaaga acggaaccga attgcccgag acatccatga caatgtcggt
     2641 catctgctgt caagtgcgat tttacaaatt ggtgcgcttg aaatgatcaa tcaagaacca
     2701 aaactaaaag aaccattaga aaatttaagt gccaccgttc acactgggat ggatcggatt
     2761 cgtcaaagtg tccatgacct ccatgagaca tcgatctctt ttcaacactc cttagagttt
     2821 ctgatcgctg attttccttc ttctgttacg attgaaggaa acttgtttga aggattgaat
     2881 gaaacgcagc aaaactgctt cttaatggtc atcaaagaag ccttaaccaa cagtatcaaa
     2941 catagtcatg ccaaaaccgt tgttttacat tttcgaacgt tgccggcctt ttatcgcttg
     3001 caaatcacga atgatggcac cagcccacaa aaaaattctg ctcccggtat tggtttgaaa
     3061 acgatgcgtc aacgtgttca agaacaaaag ggacaagtcc atattttcca agaaaaccag
     3121 caatttcagt taacgatcat tttaccaagg gagggacacc aatgataaca gtagtcatta
     3181 ttgagatgat ccatttgtga cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat
     3241 ccgtgtgtta ggcattggtc attgtgccaa ggatgcgcta gtcttatacg aaacccatcg
     3301 tcccgatgtt ttgctgacgg acatccgcat gcctaaacaa acgggcatcg atgctgccaa
     3361 agaaattttg gctaaatttc ccaaagccat ccttttgctt ttgacgacat tcaaagatga
     3421 agaatacatc cgcgaagcat tttccatcgg tgtcaaaggg tatttaatca aacagaactt
     3481 gcaagcgatt attccttctg tcaaatccgc ttataatgga caggccgtat ttggtaatga
     3541 aatcatcgag actttcactc aaatgatgaa gaataaaccg acgattgata gtcatgctta
     3601 tgcttctttt agtgaacgtg agcttgcaat catcaaagaa gtagctgccg ggaaaaacaa
     3661 taaagaaatt gcagatgcct tgtacttgag tgacggcact gttcgcaatt acatcagcca
     3721 attactagaa aagctagatt tacgggatcg cacgcaattg gctatctatt tttatcagca
     3781 tttgcaataa gtcttatcta acacaaaaaa acctgaatga tgctccttcg catcattcag
     3841 gtttttttca catcttctat tcaattgtcc cgcaaaccat ttcctcacga ttgaaagaat
     3901 caaggattcg cagggctgcc aggattcgtt ggattgttcg gcgtgttagg cggaaaaata
     3961 ggcgccttgt ctaacgtttt ttctagtttt gattcttcac gatcgtctcg ttctacatca
     4021 ggactttcat tcaatttgaa ttctttttcc atctcatcta actttttaaa gtcattgcca
     4081 gattcttttg ctaatttcgc taatttatct tcggtttctt tagccataaa gtaacgcccc
     4141 ccttttgatt tcagcttagc atatcacact gaaaaaacaa aagaaaacgc taaccaacga
     4201 tcatttttag ctatttctca tctttaaaat caagcatttt ttgccggtat aaaatcgtag
     4261 ggagaactgt tttccatacc aatcatcgga tctactaact ggttatcgat cacttctgct
     4321 gtaagaacga aatctttaga aacagcaggt tctacctctt ctttcttttc ttctccaaca
     4381 aatgaagaaa acagatctgg ttccactgtt tccattactt ggtttttcgt ttcattcgtc
     4441 ccactgtcat cttctacagg tagcttttct tttacaaccc gtggctcttt tgtatagttc
     4501 ccatcttcaa atggatcatt tccgaccaaa gaatcttcat aagctgctag tttggtccgg
     4561 agagtgatat tcattttatc attatccatg atccttgatt tcaacgtagt catccggctt
     4621 gctgattcat tcgctacaca agtgacatag gcttgctctt cccctaacaa aatcaacagt
     4681 tccttactgc gagtcactgc cgtgtagagc aaattacgct gaagcatccg ctgatattga
     4741 tggaccatgg gcaaaataac catcttgaat tcactgcctt gtgatttatg gattgagcaa
     4801 caataagaaa gagtgatttt attccattcg tttcttttat aagtgacctc atttgcatca
     4861 aactggataa ctaattcatc cactttatct tcagaatctt ttgccaagat gatacccgtg
     4921 atttctccca tatctccatt gaatacattc aattcgggag tattgactaa ttggaggact
     4981 ttgtctccta tccgataaac ggtgtcgttc caatgtactt ccttttttcc aggtttccct
     5041 ggattgaata tctcctgcat cattttattt aacgcatcga tccctgcagg tccccgatac
     5101 attggtgcta atacttggat atcttgtgca cggaatccct tatttttcgc tttttccaca
     5161 attttagaga tcaagggttc aatttgataa gcatcacttc ggaaatagga acgatctttt
     5221 tgattctttg tgaaatcttt tggcagacgt ccttctttga tctcatgggc aagaggaata
     5281 atactagaac catcaccttg ccgataaatc tgattgagtt ccattttggg aatttgttcg
     5341 atttccaaaa gatcatggag tacttgacca ggaccgacag agggaagctg atctttgtct
     5401 cctactaaga taacttgcat attcgtcgga atcgctttga ataatgtgtt agccagccat
     5461 gtatcgacca tagacatctc atcaacaatc aaaagtccgc cttctaattc tttcgtactg
     5521 actgaaggtg ttttttcccg tccattcagc cccagaagac gatggatcgt actggcaggc
     5581 agacctgtcg tttcgttcat tcgtttagct gctcggccag ttggtgctgc aagtagaata
     5641 ggaaaaattt cttgggtata ttttgaagga tccaattcca gtccgttcaa ctctgcaaaa
     5701 agattgacga ttccgttgat cacagtagtt ttccccgtac ctggtcctcc tgttaaaata
     5761 aatagagggg aacggattgc ttcagcgata gcttgttctt gcgaaggtcc atactgtatg
     5821 ccgaatattt tttcgatacg ccgaatattc ttctgcactt ctttttcagg ataatggatt
     5881 tcttttttac gactgagaag gcgctggatc gaattaccga tcccccattc agaaaagtac
     5941 aaactgtttt cgtaaagatt agtctcttct tgttgtatct ttccttcttc aacaagttgg
     6001 ataattacag tagcaacctg atcaggctgg atttcaattg ggcgacttgt ttctaaaata
     6061 cggatcgttt gctgaagcaa tgtctccgcc ggtacgtatg tatctcctgt ttgaactgca
     6121 tgctgaaaaa tctgatgcaa gatagctgct cgaattcttc tcggtgaatc tgctgcaata
     6181 ccgatttgtt cggctagatt atctgcacgt ttgaacccga ttccttctat gtcttcgact
     6241 agctggtacg gattttcttc gatgatatcc aaagactcgt tcttataggc ctggtagata
     6301 ctgaaagcta actgactacc gaacccgtaa cgattcagtc ccatgatcac ttgatccatc
     6361 ccgtggttta gccgaatcgt ctcagcaagc atttctcttt ttggcttcgt caaaccggag
     6421 atttgtttta ataccgaagg atcagcaatg attttttcga tagcatcttc tcccagcaat
     6481 tctacaattt tttctgctgt tttcttcccg attcctggga atttttcgct ggaaagatac
     6541 gctacgatcc catttgcagt tgttggcttt tcttgctcat atctttcgag tttaagctgc
     6601 cttccgtatt taggatgatc cactaattct ccataaaaac gataagtctc attttcttga
     6661 atatcgccga aacttccggt gactacaatc tctttttcac ggtaatcagc tgtggtttca
     6721 ctgatgtgta ccaaaagcac tttgtaaaaa ttactaggat tttgaaaaaa aatcgcggca
     6781 actgtaccaa cgaaataagg catttcttct ggctgcatcg gaagccgcct ccttcttcta
     6841 tagtaaaggt tctggtgctg tttcagttcc taaaaaatct gtttggttcc atactttcag
     6901 ttcatatggc aataatctgc aaggctcttc agtctctaaa atcgtcaaac tactattgaa
     6961 caatccaccc atttcacgca actcacttag ctcttttcct gtcatccatt gaatggctgc
     7021 agttaaagaa gctccatgtc ctacgaataa aagtgggcca tctttatgtt gggcaaccgc
     7081 atctgctaca acagtttcga tacgtgtgat tgccgattca atcgtttctc cgtgaaaagg
     7141 agaaggatca tacagatcta aatgattacg caaattcggc agattatccg gatatttctg
     7201 gtacatttca tcgatcgact gaccttctaa agtacccagc cctagttctc ttagcttatc
     7261 tgtataaaaa atctctaccg gacgagcaag ctctttgttg ataccttctg ctgtatcacg
     7321 tgctcgcttt gctgtactgg aataaattgc tttaaaagga acatatttta cctttttccc
     7381 aaatgctttg atttcttcgt aactttgtgg caaaagcgga gaatcgccat tgctcccttg
     7441 aaaacgtctt tcctgattcc attgtgtctt cccatgtcgg gtaaaatata gttccatacg
     7501 cagcaaactc ctgtctttct tttattttac tctataataa actgtctaat ccagcttgtc
     7561 attttcatag tgatgcgtca attctaaatt agggaatcct tgctggcgaa gtgcttcata
     7621 cactatcatt gcagctgtat tcgataaatt caatgagcgg acatgctcat cattcatagg
     7681 gatgcgtaaa cacttttctt cgttttcacg cataaatgtt tctggcaaac cggttgtttc
     7741 ttttccaaat aaaaagaagt gctcttctcc atcagcaaaa ttttcgtcac tatatacttt
     7801 atgggcaaat tttgagatca aatgtagttt acgattacct aaaaatgtta aaaaagcttc
     7861 taaattactg tggtaagtaa tatttacatc attccaataa tccaaccctg cccgttttag
     7921 atgtttgtca tcagttgaaa aacctagtgg ctcgattaaa tgaagcggag tattcgtggc
     7981 tgcacacgta cgggcaatat ttccagtgtt tgcagggatt aatggttcaa ataaaacgat
     8041 atgattcatc aggatcattc ctctcatatt tatgttcgtt tctattttct gacaatttga
     8101 tttttgcata aaaaaaaacg tatcaactcg gtgtcagtca ctgcgagtcg ttacgttagt
     8161 gaagctcttc tcactaactt ttatcagaac aggaacctga taaaaaccaa tgaaaaaaca
     8221 acttgttgct aatataacac cctcaacttt tttttgcaac ctctactcat taaaaactgc
     8281 tagaaaaacg ttttctctta gttcctttta ataattctat gtcaattgta atcttcttca
     8341 aaggattctt atataagtct gctttgattc gctcttctac ctgccattct aaaggtgaca
     8401 tggccaaaag atctttttga ttttcctctg gtatctcaaa ttcataggtt acacgctgac
     8461 gttcagttaa tttcattgct tcagcaaact tggctactac acgttcattg gaataactct
     8521 gtttttcagg ttgattcgga taaaaagcct gacgtagttc ctttaaataa ttttcttgtg
     8581 gcaccacctt caacacttct ccatcttctg agagtacacg ttggaattct tggtaatgag
     8641 aaggcgaaaa gatatttaaa accgcgttga atgtttgatc agcaaacggc aaattggtca
     8701 aatcagctac acaccaaaat gcttcggcag attgttctgt agctgcgtag actccttctt
     8761 ttgaaatatc aaatccaaca gcattttgaa tctttttcaa ttttgaaagt tcattcaaga
     8821 agctaccttc tccgcagcca acatctaata gcgagacttc ttcaggtaaa tgctgcgcaa
     8881 tagtctcaat aacgggctga tacatgccag attggatcat tctacgcctt ggaacgaaca
     8941 ttccttgatc gtattctgtt ttaaccgcat gggataaaaa ataaagtgtt ccttttttgg
     9001 aaaggtcaaa acggtgatta tttttgcata tcaagccatt atcagacttt tttacttctt
     9061 cttggcaaac cggacagcgg aacagctgat gattttctgc caaaaactgg cgtcctcggt
     9121 caattttttt taacatagtt ccccctcatt tctgttttat cttaccgtta gatgctcact
     9181 ttggcaactg ctaaaaatat gatacaatgc ctagaagaaa gtgaaagata aaggagaaga
     9241 ttagatgatc aaagaatttt gcgctgaaaa ctacacatct attcctctag caattgctag
     9301 aggagccgat cggatcgaat tgtgtgacaa cttagcggtc ggtggcacaa ccccgagtac
     9361 tggtgtgatc gaagaaacgt taagttatgc tggggaaaaa gatatccccg taatgacgat
     9421 tattcgtcct agagggggcg acttcgtcta taacgatatc gaattgaaaa tcatgcatac
     9481 tgatttgatt gaagcaaaga aattagggac ggatggcgta gtatttggtt gtcttactcc
     9541 ttcaggctgg ctagacgaag aggccttaga actattgatc gaaacagcag aagggttgca
     9601 gatcaccttc catatggctt ttgacagtat tcctgaagat cggcaattcg aagcaatcga
     9661 ttggctggta gaacatggtg ttgaccgtat cttgactcat ggcggtcctg ctgacaaaac
     9721 tattgtagaa aatttcccac ggcttaaaga attgattgcc tatacagatg gccgcttaat
     9781 cattttgcct ggtggtggtg tcactgcaga gaatgcagca catgtagcta aagaattgaa
     9841 cgtaagcgaa gtacacggaa ccaaaatcgt ggatcttcag ttataatctt ataaacaaaa
     9901 aaacatttgc aacaggcata atgcttattg caaatgtttt tgttttttta cataaaatag
     9961 cccataaata aagaagcaat attgaaataa atcagtacac tcgtcaaatc gctcaaagtc
    10021 gtgataaagg gaccgcttgc tactgctgga tcaaatccta gacgatccat tagcatcggg
    10081 attaaactac ctgcaagatt cgccactgtg attgcaaata gcatagccat ccctatgaca
    10141 aaccccaaga taaaattatg tttccaaaaa cctacgatta gaaaaatcgt gatccccgta
    10201 acagctcctg tgacaacgcc ggtcaagact tcagccaaaa caagtcgaac aaatccatga
    10261 tctttctcat cagaaatcgc aagtcgacga acagccacag ctagcgactg ggttccagca
    10321 ttaccggcag ttcctgtaat cagcgaaatg aagactgcta aaatactcgc ttcacttacc
    10381 aagtcttcat agtgactgat taaagaagcg gtcgacatac ccaaaaacaa cagagtgatc
    10441 agccaaggca aacgtcgaga cgctgccttt actggatttt cattaatttc ttccacattg
    10501 accccggcaa gtcctgaata atcgctagca gcttcatcat caataacgtc gatgatatca
    10561 tcgactgtga cgattcctaa caaatgatca tcataatcgg taacaggaag agctaagaag
    10621 tcataatctc taaatgtttg tgccacatct tcttggtcgt cgcctacatg aactgaaagc
    10681 actcgttcgc tcatcagatc agaaatcatt gcgtcgtcat cattcacgat taggtcgcgc
    10741 agagaaataa cccctactag ctgaccttct tgattaacga catagatgta atagattgtt
    10801 tcagctacat ctgcttcgtt cttcagcacg tacatcgcag agcgaacagt ttgattggct
    10861 acgatcgaaa caaattcagt tgtcatgatc gcgccagccg tttcatcctc gtaatggaga
    10921 agttccttga tttcactggc atcgtctgcc gacatcaaac ttaaatattt agcaatttgc
    10981 tttttatcca gcgtattaag caagtcaaca gcattatctg tatacatctc agaaagcata
    11041 tcagctgcat agctaggacg catttcatct aggtattctt tcatatgttc gttgtcttct
    11101 tcaatcacat cgaacatatc cgctaattct ttaggcgaca gataggaata gatcagctgc
    11161 ctgttctctt ctgtaagaga ttggtagaat tgcccctgct catagatatg catctctaaa
    11221 aaactgtttc tgaatgcctg aatattattt tcccttaaat cttgagtcaa ctgggcaaat
    11281 ctttcctcta attcttgatt ttcatccaaa ccaatctcac ctcgccttat tcttcaaacc
    11341 gtctcacaac tgcctccatg tctgcggcta aaggctgctt gaactccagc aactcttctg
    11401 taaatggatg gtaaaaacgc agatcataac aatgaagggc ttgtcttttt attcccagat
    11461 ccattcgccc gccatacata tcatcaccga gcagggcaca gccaattgcg gaaaaatgaa
    11521 ctcttatttg atgtgtcctt cctgtatgca gctggatatc aactaacgcg atttctgtta
    11581 gtcgcttctc tatccagtac tcagtctgtg ccgaacgtcc ttcatcagag accattcgct
    11641 tcaatagcga agaataatct cgggcgatcg gcaaatcgat atgtccatgt gccgataaat
    11701 ctgaaagcct tccactgact aaggcctgat attttttcac aaacttcttt tcacgaagtt
    11761 gcatatctaa ttttgcgtgc gcaaatccat gctttgcaaa aagcatcaaa ccagatgtat
    11821 cccgatctag tcgcgtcacc acatggatta cttggttttc gtaaccttgt tttttataat
    11881 aagcctttac acgattagcc attgtcccat ttggatggta ttgggcagga atagacgaaa
    11941 cgcctgctgg tttatttact accagaacgt gttcatcttc atacacgata tcgatcggtg
    12001 tttcatccaa aagtacggtt tcatgttctc cttcagcagg aatcacaatg gttaccttat
    12061 catccttagc tagagaaaac aagacatttt ctacttgatc attaactttg atttgaccgc
    12121 cttgaaattt tattttcgct aacagaccct ttgagatccc tttttctttt aaaaaatatt
    12181 ttacttgctg agaatgatct ttctcataat cccatgtaaa ctgcatatca atcctcacta
    12241 ataaaggcat ctttcacacg atgccaaaaa tgcatatgtc gataagaagc aaaatggatc
    12301 cgttcttctg ctattcgata ataaattgag cggatatttg cttttgcgac attcaattga
    12361 tcaaccgtta caagataatc ttctgtattt tccaatttta tttctagcca ttcatcatgg
    12421 gcaatcacga tcggagaacc caaagtacga aacactcgat tattcagtga agcaatctct
    12481 gccaactgaa aggcattgat actaggatgg atcacagcac cgccgacact tttattatat
    12541 gctgtcgaac cagtaggcgt agaaatcgtc aatccatctc ctctaaaact ttcaaacagc
    12601 tcgtttttga tgtatacatc ggctaccatc gtacgattgg cccgtttaat cgttgattca
    12661 ttcagtgcta aaaaatgctg gtccggtgtt tcatccaaat aactgatccg aacatccagc
    12721 aagggataac taacactttg ttcccggttc gttcgtaagc tgtctactag ttcttccagc
    12781 tcgtaatccc gccaatccgt gtaaaaccct aaatgacctg tatgcacgcc caagaaacgc
    12841 acatcattca gacaatgact gtagtgatgg aacgccgaca ataatgtgcc gtctccgccg
    12901 actgagatga ccaattctgg ctcatgatca tctcgttgaa tccctgcttg ttctaaaagt
    12961 gcgttcaaac gttctgtcac ttctatagtc tttgcttctt tattatgaac gatcgctact
    13021 ttcatcccct gcctcctctc tttcgctttc tttcttcaaa agcgttcgat agtagacatc
    13081 atctgatttt cctcttccat gggagaataa ccgctgtgct tcttggattt cttcacggat
    13141 actggacatc tcttcatcca actgataggc agcttctgcc gcacgctgaa gtcgttcact
    13201 catttcttct ggaaaaacgc cttgatattt ataattcagc gaatgctcaa tcgttgccca
    13261 gaaattcatc gcaagagtcc gaatctggat ttccgccaaa attttcttct caccgctgat
    13321 cagctgtaca ggatactcga tcaccagatg ataagaacgg tagccacttg cttttttatt
    13381 tgtgatgtaa tctcgttctt ggagaacttt catgtctttt cttttacgga tgatctcaac
    13441 aacttgatgg atatcttcta caaactgaca catgatcctt aacccggcaa tatcagacat
    13501 ttcttcttct aaacgtccca ttggaatatg ccgtaattgt gattttgtta caatactatc
    13561 gactggcttg actctcccag tgacaaattc aatcgggaca tgtcgatttt gttcacggaa
    13621 ctgtttgcgg atcccccgca gtttcacttt caattctgat acagtttgtt catatggtgc
    13681 taaaaatgct tcccaatctc gttccatagc tgatacctct acttcattaa cattcattgt
    13741 ttattctacc atatatgcaa agttttttcg tactcttgat ttatgcattg accaaaaaaa
    13801 gaaaattagg caaaatagac aaaaaggagt cgatcaaatg acacaaatgc ttgaaatcga
    13861 atataaatct atgctgacaa agcaagagta cgagatattc atcgctcact atcaattaac
    13921 agataaagat ttccgtgtac agactaatat ttatttcgat accgttgatg aacagctgaa
    13981 gaaacaaaat tgtggcctac ggatccgttt cgttggtcat caagctgaat atacattaaa
    14041 aacacctgct gaaaaagggc gtctcgaaac aacggatacc tttataacag aagaagcaga
    14101 agcatttatc ttcgaaaaac gtctgcctcg ttcaggcgca gtttttcaaa aactttctga
    14161 tttgaatatc gatcctgctt cattaatcca aaccggaaag cttacaacaa aacgggctga
    14221 attccctatt gaagaaggac ttttagctat tgatgaaagc tggggagaca atctacacga
    14281 ttttgaactg gaactagagg taggggatgc atctgtggga aaaattgctt ttataaattt
    14341 tttaaaacgt ttttctttac cttatcgtcc tgctaagaac aagatccaac gtatgcttga
    14401 agctaaaaat tagaaacctt tcattttcac aaggcacttg agttcatttt tttacttttt
    14461 tctgttaagt tataggatgt gaaagaatct agtcactagt tgtatagaat ctattttggg
    14521 ggagattcat atgatcgaaa tctatttatt tgttaatcct ttaggggaat actgtttcga
    14581 aatggaacaa cagttattac aatttatcga agaagagtac gggacaccat caaaagaaaa
    14641 gatgcaattt cgctttcttc ctttggtcaa tttgcagaca attggggatg tcatgcaaca
    14701 aaaaggaatt tctcagaaca atcttgagga acgtaatcac ttattctcaa tgacttattc
    14761 tgcagcattg gactgcaaag cggcgcagtt tcaaggaaag aaaaaaggcc gccgtttttt
    14821 gatcaaattg caagaagcag tcggctgtaa tgacatacca tattctcaag aacttgctga
    14881 atccatattt gaagaaatcg gcggcgattt gaatatgttt aaagaagatc gtcagtctga
    14941 cttcgttaaa gaagtattct tttctgatca aaaaattgct cgggaaatgg gcatcacaaa
    15001 acacccttct gcagtcgttt acaattatgc ctgcgaccgt gattttggtg ttttagtaga
    15061 agtaaaaggt acaagtagcc tttggagaat cacagagctg tgtaaaacaa cagataactc
    15121 atatcaagtt tttaatggtg aacatttaca tacaaatgat tctcagttcc attcaagaac
    15181 tagccattta cacttgcttt ctaattaaaa aaatacgtcg actcccttac aagagagccg
    15241 acgtattttt ttcgtttcta ttcgagaaaa tcaaaaatag aaagccttat aaacgatcga
    15301 tcaattcttc taattcattt agacgttgtt caaacatcga cattgcatct tcaatatatg
    15361 cagcctgtgt catatcaact cctgcttttt tcattacttc cacaggataa tcgctgttac
    15421 ctgcttttag gtaagccaag tagttctcta gtgcctctgg ttcctggttt agtattttct
    15481 tcgccagtgc tgaagcagca gaaaagccag tcgagtattg gaaaacatag taattataat
    15541 aaaaatgcgg tatccgtgac cattcgaatt taatttctgg gtcttcttcg actgctggac
    15601 cataatattt tgcattcaat ttaccataac tatcacttag gtattcacta gtcaatggca
    15661 cacctttttc atcttccgta tgcatgaaat gctcgaattc agcgaattgt gtctggcgga
    15721 aaactgttcc tttaaaccca tccaagtaat ggttgagtac ataagcccgt acacgagggt
    15781 ctttttctgt ttccaataaa tactccgtta ggatattttc attcgttgtc gaagcaattt
    15841 ctgctaaaaa gatggagtag tcgccgtaca cataaggctg gttcgaacga gtgaaataac
    15901 tatgaacact atgtcccatt tcgtggacaa gcgtaaatag ctgatccagc gtatcatgcc
    15961 aattcaataa aatatatgga tttgtgtcat agcttcccga agaataagca ccgcttcgtt
    16021 tccctttatt ttcgacaaca tcgatccaac gttcagagaa tgctttttct acgatggcca
    16081 tgtattcttc acccattggt ttcagtgctt ctaaagcttt ttcttttgct tcttcgtacg
    16141 taaaggtaat tggagcttcc cctaagaccg gtgtataaag atcatacatg tgcagttttt
    16201 ccacttctaa taaacgtttc cgtaattcca tgtatcgatg taacaaaggc aaatgcttgt
    16261 ttaccacgtc taccaaagta tcgtatacac tttcaggaat atgattattg ctcaaagacg
    16321 cttctctggc agagctgtaa ttacggactt tcgctttaaa attatgtcct tttatatgtg
    16381 tgcctaaagt agaagcaaat gtatttctaa attgttcgta aacactgtac aatcccttaa
    16441 atgctgcttc gcgcaccctt cgatccgtgc tttctagcaa ctgaccatac acgccatgag
    16501 ataattggac tatttcacca ttttctcctt caatcgttgg aaaaactaga tctgcattat
    16561 tcaaaacagc aaatgtatca cttgaagcat caaagatttc acctgctcca gcaagaagag
    16621 attcctgctc agcagataag acatgggctc gattatctac tatttgctgg atataatggc
    16681 gatagacttc caattttggt tcttctttga aatattgcca aatctggtca tctgacaatt
    16741 gcaatatttc tggttcaaac caggaaacgg cttcactaac tttcgaaaac agactgcttg
    16801 ctcttgcata aagcgcttgg taatctgtat ttccagtgtc ttgatcgttt ttaaggtgcg
    16861 catatacata aatgacttca gtttggcgat aaaccctcaa tacgaattca atcgcattta
    16921 aaaattgaga agcgccttga tcaagtgttc ctttgtgttt ttcagattgt tttaactctt
    16981 ctgataattc caaatatttc tcatcaaact cttggtcgct tgaaaagatc ttggtcaagt
    17041 cccaagttaa attttcaggc aattcttctc gttttggcaa ctgctttact tccatgaaat
    17101 ccactccttt tcttccctta gctctatcta tcaaaataga tcatagtcta acatccacat
    17161 gtcacagcat ctaacttttc tactcattca tgtgtctgct tccatcaatt ttagcataac
    17221 taaatcttgt tttacataga aaaccgattc ctagcctatt tttatactta ctattttttc
    17281 aaagaagaca agtgtatgca ttcgttaaaa aactgctgat agaccatctc ttcatcaatc
    17341 ataggaaaaa gccattccct tttatgttct tttatttggc aaagccatga gttgaaatca
    17401 ggaactttct ggttttccaa ggcttcttcg tacaacattc gataaagaaa aacctgttct
    17461 tgtaaataaa agaaaaaccg acttttttga tagatccacg atgatagatg caaaagatgt
    17521 ttatgacgca agtagcattg ttcttgtatg gatactgtat tcttttgctt gtgaataagt
    17581 tggcgtgtca gccatttctt cccatcttca ctcacttttt ctattttttt catttggttc
    17641 attttaattt cgttactagt gaatatttct ttaaggtccc tactagaaaa agtccagcag
    17701 ctactgcaaa aggaaatatg ccctgataca gtctctgtaa tatgatgata caaataaagc
    17761 ttttgtttct tgagatcagc tttccagcaa tgcactcctc tttttctatt atagtagcag
    17821 caactttttt ctatcaatga gaattgcgat tgtccaagaa aagaattacc aagtatccac
    17881 catacttggt aactgttatt caaataattt tgggttcttt caataaatct ctggtgagac
    17941 agtctagaac attggatttc tattgctaga ttcgccaaca aaatatccgg cctttgccgc
    18001 aacctcggca aataggcttc caaaaatact ggttctactg actgtcccag ccaatccatg
    18061 aagcattcct ttaactgtaa gtgctctttt gattctcttt cactaaagac cgaacagtta
    18121 tctgattttt gatgggcaaa atgagcacat tttttctttc cctttttcaa aatcactctt
    18181 tttcgacagc cacgacaata atatttcttt cctttttctg catgtttagc aaaacagcac
    18241 ttattatatt cattcattgc aagcagcatt tttctccctc tgaacttatt tacgtctaag
    18301 aatttattta cacgaaaaaa gagggcgtga aaaagctatt ctgcatcaag taataagaac
    18361 agctaaacaa aaatagttcc caatattttt cgtttggttg ggcttgttac cgcagatgca
    18421 agcttttgaa cacatttata cgaaaaaaag actgcgacac aatttttgtc acagtctctt
    18481 actataatgc tgatttatac aaaataaaat ttcgttcgct cgatagcatt acgcgccatc
    18541 agacattgtc catattcatt caatgtttct ggtgtacgat cgctcttttc agcaaactcc
    18601 aaaattcgag caatctgatt ctctacatcc gcttggttga gattttccat ccagaagtga
    18661 acgactaggt aatagcgctc ttcgaataaa tacaaatcag tccaagcaga ctctagttcg
    18721 acatctgttg caagttggat cacttgttca aaatcttcaa aagcaaaagt tgcttgtctt
    18781 tcctgttctt ctagggcgct tccagataat tcttcctccg gatcgctgcc aataatctgc
    18841 tgacgaagaa agtcactcac atcttctgaa tcaacagtag aatcttctga ttgagaaatt
    18901 tcttcatccg gaagattttt actgataaac agttctaatc cgtctccttt tggcaaaact
    18961 tggaaagtga cagcttcgct tcctcggaac tcctcttcga tatcaacttc ttccaaaata
    19021 ctataaaaga aattttcgat ttctttgtga ttgccaagta aatccaaaaa tgaaacgccc
    19081 cgttcctcta aatcttcatg accaattagt acacggatcg tattttcatt aatatgttcc
    19141 atttccattt tgctacacct cactttgcca caatgtttaa tatagattca ttgtagcgaa
    19201 atcagcttaa atgtaaagaa aaaaaatctc gctgttaagc gaatttaata aaaccagcgg
    19261 atttttcaac ctttcaagct atcttattta actataacat ttttggcaga cgaatactat
    19321 atagccgact tttcagctaa ttttccctct ctatttttcg tgcaatcatc atcttctact
    19381 acctttttat acatctaatc aagaatactt tttgtaaaaa caaaaaaact tggaaaaact
    19441 atctttgtaa tagtcttt
//
LOCUS       DAFTHM010000047        18763 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFTHM010000047 DAFTHM010000000
VERSION     DAFTHM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.047"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(365..2000)
                     /locus_tag="L7C88_001618"
                     /pseudo
     CDS             complement(365..2000)
                     /locus_tag="L7C88_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2555..3118)
                     /locus_tag="L7C88_001619"
     CDS             complement(2555..3118)
                     /locus_tag="L7C88_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBP9558440.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(3133..4176)
                     /locus_tag="L7C88_001620"
     CDS             complement(3133..4176)
                     /locus_tag="L7C88_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558441.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(4309..4713)
                     /locus_tag="L7C88_001621"
     CDS             complement(4309..4713)
                     /locus_tag="L7C88_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBP9558442.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(4946..5581)
                     /locus_tag="L7C88_001622"
     CDS             complement(4946..5581)
                     /locus_tag="L7C88_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBP9558443.1"
                     /translation="MIFLQKYGFYFLLLGVMSDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILVVATVGLYGIGDCIFT
                     GLFSINTNESSCNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(5847..6899)
                     /locus_tag="L7C88_001623"
     CDS             complement(5847..6899)
                     /locus_tag="L7C88_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9558444.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(6912..7850)
                     /locus_tag="L7C88_001624"
     CDS             complement(6912..7850)
                     /locus_tag="L7C88_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBP9558445.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(8301..8951)
                     /locus_tag="L7C88_001625"
     CDS             complement(8301..8951)
                     /locus_tag="L7C88_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558446.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNINHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(9051..9560)
                     /locus_tag="L7C88_001626"
     CDS             complement(9051..9560)
                     /locus_tag="L7C88_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBP9558447.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(9761..10630)
                     /locus_tag="L7C88_001627"
     CDS             complement(9761..10630)
                     /locus_tag="L7C88_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBP9558448.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(10650..11771)
                     /locus_tag="L7C88_001628"
     CDS             complement(10650..11771)
                     /locus_tag="L7C88_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBP9558449.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(11773..12168)
                     /locus_tag="L7C88_001629"
     CDS             complement(11773..12168)
                     /locus_tag="L7C88_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBP9558450.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(12187..12993)
                     /locus_tag="L7C88_001630"
     CDS             complement(12187..12993)
                     /locus_tag="L7C88_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBP9558451.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(12986..13774)
                     /locus_tag="L7C88_001631"
     CDS             complement(12986..13774)
                     /locus_tag="L7C88_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9558452.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(13788..14264)
                     /locus_tag="L7C88_001632"
     CDS             complement(13788..14264)
                     /locus_tag="L7C88_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9558453.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(14336..16993)
                     /locus_tag="L7C88_001633"
     CDS             complement(14336..16993)
                     /locus_tag="L7C88_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBP9558454.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(17012..17416)
                     /locus_tag="L7C88_001634"
     CDS             complement(17012..17416)
                     /locus_tag="L7C88_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBP9558455.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(17648..17905)
                     /locus_tag="L7C88_001635"
     CDS             complement(17648..17905)
                     /locus_tag="L7C88_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBP9558456.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(18030..18362)
                     /locus_tag="L7C88_001636"
     CDS             complement(18030..18362)
                     /locus_tag="L7C88_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558457.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT         5951 a         3777 c         2744 g         6291 t
ORIGIN      
        1 tttctcagaa acaaaccact cattggaaaa gacatgaatc aaatcatcac ttacttgtgt
       61 aaaatagcga cgtttaatga caaagatatc ttcattgcta tctagtgtac cttcatttct
      121 ttgtgcttaa attcaaagat aattttctca ataaagattt ttgattccag taagattcct
      181 ttactccttt tacaacatag cgttgtcctt tgttttgaaa catcttcttc ccctctttgc
      241 cattaaaaat agcccaattc tctataaaga agattaagct tcattattat aatataaagt
      301 ttaaatttgg tttattactt actttttctt attctctagt aagctaatat tgaaaaaaat
      361 gtaatcagat cattattttt atatgttgta acttcctgat aagaaaacta attaaaagaa
      421 agaggtaact acataaacta attaaaaaag ctaacttcat agttggagga taaatggaag
      481 aaacttcaat gattgtttct ccttgtgttc cttcaatcga cactagtcct attatcaatc
      541 tctctttttt gtccatttac ttttgcgact gttccccaat aatcaaatac aggaagcgtt
      601 attttttgtc ctttagattc atgtactgta tagactattt tcgaatccat cacttgataa
      661 ggcatagtat gccattcctt gccaattctt acttcatgat tctgcaaatg ttctttgtat
      721 tgtaatgctt ccgtgggtgc atagtcataa agtcctccgg gaaggagtgt cgtgtaacga
      781 ataagatttt cttgattcat taccaagtga tctctctgag tgacaacttt atgttcatag
      841 tttgcttttg ttgcagcaga tacagccaac agtaataaaa caattgccgt tatattaact
      901 acttttcttt gcttagctga tgtgctcttc atgaaaacga acgataaaat caacgagcca
      961 aacagtactt gaaagcctaa gattcgccaa ggaaattgaa tcatttgaat gggtgtattt
     1021 tgtaataaag accatggaaa aaatttggtg gataagagcc aagagactac cgcactaagg
     1081 taaatcactt tttctttgcg attaaatcct ttaaaaaaga agagtggaca gatcaaagaa
     1141 ataataccaa tgattcctac cgtaaaggtt gtcaggtcat tattcatcgc accaatcaaa
     1201 ctatccgaga catttaatgc ttggtgttgt aaggtcgttt tatctggctc attaatcgat
     1261 tgaaccatga tttgtcggaa catcggatac caaaagtatg ctgttaaaag aatcgtcatt
     1321 cctactgcct ttgacaactc cacaatcaac cggatgcttt ctttttttct tgtttcactt
     1381 actacaaagc cgcctaagac tagtaagcca acggctatta cactcataaa agtggaaaga
     1441 acatgtgtat aaatgagtaa gctcatactg actgctaatg gaattgcaca tggctttttc
     1501 tcataaatca gtgcgtaagc ataatacata actatcggta taaccgtaag tgcaatcgct
     1561 tcagcaatag cagaacgatg ataaatatca atcgtacggt acccataaaa tgtatataaa
     1621 cagctaaata taaaagccgc atcgattctt tttaaaaatt ttagtccata atgaaacatc
     1681 agcatgatag tacaaacatt caatagccaa acatataaga tataactaac gattaaatta
     1741 ttacttatcc aataaaaaat gactgccgga aaaaaggtca agtagggata aaaataattc
     1801 actccgctcc cataatgatt aaacgtcgta aaattgattg gaccagaaaa aattgaagat
     1861 aaccctttga ctctagcaaa atggaaggca atatcccccg atgtagaaat agtatgaaca
     1921 tttctaaaat aattgattga ataaagtcca gcaataattg ctaggagaat ggacaatatt
     1981 atttttttct ttacttgcat tacttaatta tatactcctt tcatggattg ctttatctag
     2041 tataacttaa attttaaata aatcgttatt tatttttact ctcacttaaa aaagcactaa
     2101 aattataaga gagggaggta atggtctgaa caccaagaat tgttccaaca tcgaattgct
     2161 taactaatga gttcaaagct taattatgtg gctcttatat ttaccgagcg tggattgcga
     2221 tctctttagc gaaacaaaca tctttcataa aaaaaacagc catatccgct ttcttggata
     2281 tgactattta ctactacttt actatctttc attcttcttg tctcacttat gataaggcgc
     2341 tgcgtatcat gagtgaatga tattaggaaa acttcataaa ataaatcttt tatacatttc
     2401 cacttctaga tggtcattca tgttagaaga atcaaactat ttttttactg tcgtaataat
     2461 attaaaacac tagaacaaat caattaaatt ccataaaata taaataatag acctagcatc
     2521 atctggtata aaatggatgc taggtccgtt atatttactc aaaattgatt ctacgaatag
     2581 atcttcttat catttctatt ttagtagtca tgcgttgttg ttcttctaaa ggtggtaatg
     2641 gtataagtag tttagataaa tttgtaccat ttacatttgg ttgcccagtt ccgtaagaaa
     2701 ttttttctaa taacttccaa tataatggcg agtctaagaa gcagtctacg tattctgata
     2761 ataatttctc aactaaccta attcgaatca agtaagaagc aaaaacagat tcctcactta
     2821 tttccttaac caagaaactt tttcccatag ttcctcctgt ccttgctatc aaaatgtcat
     2881 tttcttccaa tcttaaatca actagtttag aattactaat atcacagtaa ggcacactgg
     2941 accaatttac acgtccctct tgtatatctg tgattctcaa aaacttaaca ttgccttgtt
     3001 ttttcgccga atctgtatag ccatattgaa tcttagtaga aatacttcct aaataaaccc
     3061 atagtcgaac atcgctagat gatttttctt gtcgttcttt atgaacaaca gtgatcatct
     3121 tgagttgtcc gactattttt tagttgcagc aatctttttg ggacgcttat ttgcatgaag
     3181 caacgttgct aagtctagta ataaaacatt ggctaacaca ggattggctt tctcgcgata
     3241 cgctgcggcg ccactttcaa acaatactgc tagacgatct tctacaacaa cgatttgttc
     3301 caaatacggt ggaaatttga ttcgttttag gatccggcta ggagagtccc gctcggacac
     3361 taagagttcc gaggtataag gaccataaga acgactggct aagagataat ggccataaaa
     3421 agccacacct tgaatcttat cagatgtttt tctgctcatt gtcacggttg gttggatttt
     3481 gtctttgcgg cgaattgctg ttttcatttc agctatcgtc ggcaatagat agaaagtcaa
     3541 ctgtccttca ccttttagtg tgaagttgcc agataccagt tgatcattgt tttgagtcaa
     3601 atacgatgct tgtggaatct ctgagagatc agttgtcagc caataagcga ttggctgtcc
     3661 cgtctcttca gatgtatctg ctaagatatc gatcaaacgt aaagcggcta ctcgtccagt
     3721 agcagatcct gtgattgtca accataaaag ttcccgtttt gtatcatata ctaagccccc
     3781 tacatgtggc cgtttaggta aaatcagcag tttgatcggc tgtcctgttt ctctatccag
     3841 tacatgaata atagaatgat gctgatggtc atagcagtag gcagaaataa acacaaaatc
     3901 ttgagaaaaa gccaaccctt gcggcgtcat ccattgacaa acctcatttt cgccggtttc
     3961 cggcaccacc attcttgttt ctgttaatcc aggaatgtta tattgttttg cttcagcctt
     4021 ttcccaagct gcttgaacaa taggataccg ttttaacttt ttttcaatat cctgatgtat
     4081 ccgttgctgc ttccaatgct taaactttag gacatagtaa acaagaaggc caatgaccag
     4141 caacactaaa atcattattg ctacccgctg tgtcattttt ttgcctcctt gttctattcg
     4201 atcaatcgtc catataccgc tattaattac cgtaactaca tgtttctttt actagcgttt
     4261 ctttatagga tctttcataa tctcatttat agtaacatta agaatccctt attctactat
     4321 agtcacttcc acatcaatat tgcctcttgt tgctttagag tatgggcaaa atgcgtgggc
     4381 ttcttctgcg attttctctg cttggtcctt ctcaagtcct ggcaaagaaa cttctaaaac
     4441 gaccccgatt tggtagcccc catcttctaa ttgaaataaa gatacccgtg ctttgacttc
     4501 agaatcagac tcaagattat tttcttccag catgtgttga accgcgccgt tgaagcaaga
     4561 tgcgtatcca gccgcaaaaa gttgttccgg atttgtccct tcactatgga ttcctgggcg
     4621 gtcgatcttc atgtgcatac ttccgtttgg tgcctcaact tcgccatcac ggcctccacg
     4681 attgatcatt gctgtttcgt acattttttt cattgagatc atcctttctt tcgtcgttct
     4741 atattaagtg taacgagtat tttttaatct gacaaaggta atgcttgcat tcggcgacat
     4801 cagttagaca acatcgatga tcagtgatag aagcagttta tctatacaaa aaaagaaggg
     4861 ttctatgata tttggtgtcc ttactcgcct tgagtaacaa caccaaatat catagaacca
     4921 cttaatcagc ttcacactgc tttttctact ttcgtagttg aaaaaaactt aaacaaatca
     4981 tcggcaaata gttaaagaaa aaacttaatc gttgaaagaa gcccaattgc ttaaagaagg
     5041 caaactgact aatcgacgga atccgtgcta atccgtaaag acctgcaatt agtaaactaa
     5101 taactgttaa aacaagataa aaatggctaa gcgtaccttg accactttga cgataaagca
     5161 gaacaagtaa caatgggaaa agtagaaagc ctgcatagcc tagcccagaa cctatattat
     5221 ggatccaagt cgatagatta caagagcttt cattcgtatt gatactgaat aagccagtaa
     5281 aaatacaatc acctatccca tataaaccaa ctgttgcaac aacaagtatt gcaagtgttt
     5341 ttgatgttcc aacaaatagg tgatacaacg caggcaacga aagaacaaaa aaaagtccag
     5401 atacaactga ccagaccaag aaagcacgtc tgactggact atctacgtca ccaaacacac
     5461 taattacggt agtcatttga ttcagtttgg gataaaaaag gccaaggata tacggtgtcg
     5521 ataaatcact catcacacct aataataaaa aataaaaacc atatttttgc aaaaaaatca
     5581 ttttcttccc ctacttttta gtgattattc gatacatcca acaatcaaat tttttctcat
     5641 tttaacacat atttttattc tagttgtctt ttgaacaatc aataacataa aggtgagttt
     5701 cttctacatt ttaaaaaatc gaatggcact gaagagttca gttgtcagca tcaatctcct
     5761 actcaaaaag gcaaaaaaac gtaagtcaga tgttgttgac atctcactta cgcatccatt
     5821 gattgaaaat ttcttagtaa aatctactag cctaaaaatt tgaagacttc ttctcgatca
     5881 tacagtttaa atactttctc gcataaaaat tgagtaatta gtgccgcaaa aacagggatg
     5941 actaaccaac aaagaacaac aagaaagcca tttagccctg catctaaaga agccaacgga
     6001 ccaacaagtc cgaccacgcc gaaaccagca gaagcaggcg tacctgaaat agaaaataga
     6061 gcgacaggaa tagctgtaat cactgcacta actaaacaag gaataagaat cacaggtttt
     6121 ctaaatagat taggcatcat catcttcata gcgcctaaag caatcgcaat tgtcacacct
     6181 gacttattaa ccttccaaga gttcactact aaaacaaaag tggttgcagc tacgcccatc
     6241 gcagccgcac cagcagaaac accatctagt tggattgcca ttccgattgc tactgttgaa
     6301 ataggagaga taatcaaaaa ggcaaaggaa caaccaatca agatagacat taacagcggt
     6361 tgtaaggtag tgaagttatt aatcaatgat ccaattgcag aagtaattgc tgttacaaaa
     6421 gggaataaat aaaaaccaag taaacctgca cctacaccta caacaatcgg tgttaacaca
     6481 atcgacactg acccaaaact atttccaatc agtaaaatca gcccgacagc aatcgatgct
     6541 gtcagcatcg tattaataat atcgcctgta ccagcaccaa cgtaaacacc cgtttcaccc
     6601 aaatcaggtg tgaatttgac tacaccagaa ccaacaaaag aagctccggc tacaaccatc
     6661 attctcatcg gatcaaatcc aaattgtaag gcaatcaaac caccaatgat caaaggtgtt
     6721 gctagttgaa aaataactgc taactgtgcg atcgttaccg caaagggata cgcactaaaa
     6781 tattttaaaa tggcacctaa tactgcatta ggaatcaatc caataatgat tcctgttgct
     6841 gtaccagcga ggactttatt cagaaaaatt ttcggtgata ttttttgtga agtttccatt
     6901 caatctctcc tttattttac gttcaaacta tcttcttttg catggacaag ctcagtcaag
     6961 aaatcacaat aaggcgtcgc aacaccatat ttcttccctt ttctagaaat tgcgccattg
     7021 atataatcga tttctgttaa tcgatggttc ttaatcaagt cttgatacat tgaaggataa
     7081 tgtaacccaa ttgtttccgg gtcaaaacaa gattcacaat gtgcaatgac ttctgggaca
     7141 tctagttcaa tcttctctac tgctgctact ttggcaaact cattgacaat cgtcgccacc
     7201 attttatgag cagtcgatgt ttttcctagc tcagccatat taacgtctaa gattgtgcat
     7261 agtccgttca ttgttccgtt cacacatgct ttgcgataaa tagaatagtg aatattgtca
     7321 gaaaaatgag catttaatcc tgattcagac aatttgtctg ctaatttttt tgcagctgct
     7381 tcttttccat cacctaaatt ttgtaattct actgaaccac ttccaaataa tttgacctga
     7441 ccaggacctt caagacctgc cgtccacatg gtatttccaa tatagatatt ttccattggt
     7501 acaaatttct caataatatc ttcatgcccg ataccattta atagacataa gacctctgta
     7561 tcttttttga ttaatgattg gatatcctgc agcatttttt ccagctgcat cgctttggta
     7621 aatagaataa tcagatcaac ttgatcttct ttttctactt cggattgaag aacgattggt
     7681 agttttgctt ctacctcttt accattaaaa tttgcttgta atccatgttc tttgatttgt
     7741 tggacatgtt ctgcccagcc atcgattaat aatacttcgt tcccactttg gtgaagcatc
     7801 aacccaaagc gacttcccat tgcgccagcg cctgcaattg ctattttcat tgattcttcc
     7861 tcctttttct ttctattata ctcatttgag aatcttttca caacctcgtt ttgttattct
     7921 tctcttattt atcatgttta tatccaccat tcaagttatt ttatcagcaa atcaataaaa
     7981 actggaatag aatcccaatt tcatcgtaag agaaactaga ctagcaataa gaaaatagaa
     8041 acattcatag aaaaaatctc actcctctga ttataaaaga gggggcatta acctcgtgta
     8101 tactaaaacc ttccattcat tcgatggatg attttctttt tgtgaaaaaa tattcattgt
     8161 agtacgatgt tgcgcaacac agacggatgg tattgcttat tatttattaa aatcgaacaa
     8221 tacacttatt taaaaacttc tttcccagat tttcttccat ttttacagtt ataactagta
     8281 ttatcatgaa aaatagcctt ttattgtcta tgggaataat aatttaaaat tggtactttt
     8341 ttattaatta gttcatcgcc caataatctc tccagtttct tagcatctcc tgactcaacc
     8401 ggaattatcc aagcccagtc taaataattt tttaaaatct catcatattt tgcaaatatt
     8461 tcattgccat attccgtcct taaaattata ttttcagtgc cagacaagtg atttatattg
     8521 agttgataaa aaagatctcc atctaaaaaa atatcattag aagaagattt ccccacagta
     8581 atgaccattc catcagctct atgtgttaca tacaaataat tgtatgacct catttcacct
     8641 aatgaatcaa ttatttcttg ccctttagct ctaatatatt gatctctatt acctatctca
     8701 ctcttattta acaaaagttt tttcatgtca aatttaatcg gctgttttat ttttgtaaat
     8761 tcgcttctac tactaatcca atccgagatt aatttttcaa catgtcccag agtaaactct
     8821 gatttattcg ctaaatactt tttttgttgt attaaagaca tctttccccg aagctcaaaa
     8881 ttgagcctac atcgattctc tatctcttca aaaagcatct tatcttcatc attcttatat
     8941 tcatcattca taaaaccaat ccagctcctc gattaagata atattttaat ctcatacaaa
     9001 aactagctct catcaaaaca accattgttt tgatttctca tgaaatttct ttatactttt
     9061 ctccgattat aaattcctaa ccccttgaga aaattacgca tatatttatc tccgcaaggc
     9121 ttaaaatttc gttggccttc ttttctcaaa aatgccccga tttcgccttt tgatggatag
     9181 atttctgcct cagcaaaaac gtctaaaata tcatcagtgg tcatagacaa ggcgattttt
     9241 aattttttta gcaacacatt gttgatatat ttgatttcct tgcttttttg cggcgtgtct
     9301 actatcggct tatctttttg cggaccacgc gccaagagaa tcaggccatt taggaatgcg
     9361 tcaaaaactt ggttgttgat ggttttttca tacacattat tttctgcatt atctttgttc
     9421 ttatcctgta ctttggtcag taccgcctga gcttcttctt tagtcagtgg tacaccgcct
     9481 agctcaaaag ctttaatcaa atccgtatct ttcaaatcaa tcgcataacg caatcgcaat
     9541 aacctatcat tgttattcat ttgttcctcc gaagtattta gtctttactt tcttacgtac
     9601 tttttgtctt gctaagattt ttaggatcaa tgataaaaac cgcatcactt atgataaggc
     9661 gctgggtatc atgagtgaat gatattgctg aatacaaata gtccgaccac attaagttga
     9721 tcggacttca taagcatttt attgactaat acttttttgc ttaagaattg attctaacat
     9781 cttttgctaa agttaagcat cctatagttc ctgcattatc tgctaactta ggtgtgacaa
     9841 tgtattcttc gatatttggc gtatcgacat agccgttaat tagttctaaa aaacgtcttt
     9901 gtactttctt tttcagatgt tcttgttgca tgacaccacc accaaaaatt ataatatctg
     9961 gtgaaagcat cagggtcgta ttacaggcac attgtgcaat ataatccgcc tcgatttccc
    10021 agaacggatc ttctatagaa agatcttgtc ccttggttcc cgtacgcatc tcgatagcgg
    10081 gtccagatgc caacccttcg agacaatcat gatgaaaagg acaagtacca gagaaagtat
    10141 ctcctgaatg tctcttaact aacgtatgcc ccatttctgg atggctaaac ccttcaacaa
    10201 aaatcccatc ttgtatagct cctccaccaa ttccagttcc aacagtgtaa taaacaacac
    10261 tggataaacc ttttccatga cctgaaacat actccccgta acaagcagca ttcacatcgg
    10321 ttgtccaggc aattggaatt tcgaaatgct tattcaacgt tccaacaaaa tcaaaatttt
    10381 tccaggcagt ttttggagta gaggtgatat gtccataggt ctttgattca cgatggatat
    10441 caatcggtcc aaatgaccct actccaatgc tttctaattg ttctttatag tgattaaaga
    10501 aatcaattac caaactcatt gtttcattcg gtgtagttgt aggaaaactc actctttcta
    10561 aaacctttaa atcatcattg ccaatggcac aaacaaattt agtcccacct gcttctattg
    10621 agccatacat ttcttactcc accgtccttt tatctaggaa ttcgttcttc cctgtctaat
    10681 agtttttcga aaaactcatg tggttccttt tggtaccaat aggcaacaga agaaatatcg
    10741 tcttgacgct cataaagctt gatgtcatca tttcctaggg tttggaaagt aacacgtaaa
    10801 ttttctttga aactaatggg gtcgggtaaa tgccagcggt acaacccatg catcggtaaa
    10861 gcatcatcgc caaaaccatg aactggattt ggattaggtt ttccagcact aaaataatcc
    10921 cgggtgtgat ctcttttaga ttgaaaagga tagcccataa atagcgtatt aaaattttga
    10981 gcatatgccc tttctccaaa gttcttttta tggaaagccc aagcgccgcc aaaataatct
    11041 tctgctcctg tagatgttat tgtagggaaa tcttcatctc catctatata aaacttaaat
    11101 tctccttccc cccaccagta tctttccaat gcgcacaaag caaagtaggt tcctacataa
    11161 tacccagtgc ctttgattcc atcaataagg gtgtaatctt ttccttttgt cgtgatgggt
    11221 tcacggttcc atttagcatg aaaatacatc gcatcatccg gtacttcagt caatgcataa
    11281 ttaaatgtat aaaaaatgtg cttaataaac tcaggatgtt cattcgttaa agtaatctta
    11341 gctttttttc gaaatggcat ctcaaaatag caattcatcc ctgatgttgg attcactacg
    11401 attggtaagg aattcacttc gcatcttgtc ccaaacccat tacaaaaaaa atctcctaat
    11461 ggactttcta cagaaggagt ggattcatca tcccaataaa tacgcaaaat taaatcacgt
    11521 aagacgaaac tcccagcgat tgttttgtct gtcactgtca tccaaaaatg acgtaaaatt
    11581 ccagggcctt ccatttctgc taaagtaatt gtctctccag catttatcgg aacagaaggt
    11641 gacccttttc tcccaattcc tagatgactc gctgtcattg ccgctttccc tttttcacca
    11701 tttttatttt ctggtgaaat agttctactt tcctctccct tgtggagcca tatattattt
    11761 aaacaattca ttttattcgt cctctatcct ttcttcactt ttttgattat tcatatagat
    11821 gatttgttgt tgtgcctccg caataattgc tccaatatct aaattatcat ttcctaactg
    11881 caaagcgatt gacattgcca agggaagatt cattcctgca attacgtgca ctctgtcaga
    11941 aatataggta aaaaactttt gatttacact tcctccagcc atgtcagtta aaacaattat
    12001 ttcgtctgta gtatccacta actctttaat ttgttcatct atatcatcaa tttcttcgac
    12061 atatgcacat aagctactaa tttgattatg catacctgtt aaaaactcta gtgtctcttt
    12121 aaaaccctca gctagtattg aatggctagc aatgatcaat cttctcataa ttcaaatcct
    12181 tttcctttac gctaatattc caaatgcagc cataaccatc gcaaaaacaa taacgagtag
    12241 aatcaaaatg gtcatactga tttttttctt actgagtaga taatatgctg cagcagtaat
    12301 aattactgga attaatgttg gtaaaatttt gtccaacatt ggttggattt tcatactaac
    12361 ttcaccaaaa gtgaatttaa gtggcgttga aacactgata actgaagcaa ttaatgatcc
    12421 aactactgtt agccccaata ctgaagcagc ttcagttaaa taattaatct tttcaccgta
    12481 ttcagtaaca atcttcattc cctgcttata accaaattca aagcctctca ttcggaaaaa
    12541 gaagattacc atgattaaaa tgaaccataa aaagattcct acaggattat tttctaaagc
    12601 catataagcc gcaattgatc ccatgatggt tgggatcatc gtcatcaaaa gagagtcccc
    12661 aataccagca attggaccca tcgtaccaac tttaaagtca ttaatcgcat cttttgcttc
    12721 taatccttgc ttttcctcca ttgcaacaca agcacctaaa ataatggctg ccagccaagg
    12781 ctgtgtattg taatactgaa agtgattatt taaagcttcg atgtattcat catcatcttt
    12841 gtataatttt cttaaaatag gtgacaatgc gtaagtcaca gatgcacctt gctgtgtttg
    12901 ataattaaag gtacaaactg acatcaacca acgatagttc gctttcctaa gatccttttt
    12961 cgttacttga tatttttcgc tcattttatt catcctcccc aataaaccca acatcagaag
    13021 ctcccgcaga agcagtgatt tgtgcatctt tttcagctct atgatacaca ttaaatgcta
    13081 aagcgaatcc tatgatcgcc gctccaataa taggtacctt caaaaaagcg gctaagaaaa
    13141 atccaacaag taaataacta atgtatcgac ctgtaggcat aaagcgtaac aacatcgcaa
    13201 taccaacagc aggcaacatt tttccggcta atgttagccc atccataaac caattaggta
    13261 aaacatccaa aacgtaatta acagcagact gtcctaaagt aacggcaata aatactggaa
    13321 ttgctgcaga taaaccaaag aaaattggcc ccaaccacaa aacactattc attttcttaa
    13381 attctcgttt attcgcatat tcctgtgatt tgcgaacaac aaaaccattt aagattttga
    13441 caattacatc tagttgcacc cctaacatac ctacaggtag tcctattgct aatccggctt
    13501 ctactccaag ctggctacca aatgccgttg caataattgc gcacgttcca tagtccggta
    13561 cagatgagcc accaaaaccg gcaactccta atgacatcaa ttgaactgta ccgccaacta
    13621 tcaaacctgt ttttatatca cccatcaaaa ttcctgtgaa taatccccaa aaaactgcgt
    13681 aatttacaaa gatcatcgga atcccataat aatcaacatg tttaataaat gctaatatag
    13741 tcagcataat aatttgaaaa atagtaaaat gcattatcct tactccttta tcctaatttt
    13801 gattgaattt cctgtgcctt atccgccgga acaaattgtg taacaatttc tacaccagaa
    13861 tccaacaatt ttttatacgt gctgatattt tcatctgatg cataggctct agaagatagc
    13921 tgtaatgcat tatctttaac aacagtaccg ccaacaatta gtcggtcaat tctaataccg
    13981 ttatctacta aatgaaggat tgtttccggc tctttcacga tgacaaatac tttttcctga
    14041 tcgtatttcc cctttttaaa attcgcaatc gctgtttctt cagtgataat tgatacagcc
    14101 attccagcag gtctagctaa acgcatactt gatttttgga tgtcgttatt tgcgacagaa
    14161 tcatcgatca ccatcactct gtttgcttta gacattggtg cccattgcgt gacaataatc
    14221 ccatgcaata aacggttatc aactctcgac ataacaatac tcataaatac ttcctccttt
    14281 atctttcatt ttcttacaag caattaccat gccaaaacaa aaagaacttg ataaatcaag
    14341 ctctttttac ataatcataa acgtatttaa cctcatgaat cgggatgtcg acactataat
    14401 aatgttcaac gacactgaaa gattgcttaa aatgtgtctg aaatttttga aattcctcac
    14461 tcgtttcatt gaaataaatt tcatcttcca aagtattttg ttttactaat cgttcaatta
    14521 agcaactaat gtgaacatat aatccgaaac acgtattatt atcaaatgaa attcctagat
    14581 cattttgtaa gatgtatata gcatctgaaa cccgttctaa taatttagtc ggatttaata
    14641 tggtcaattg ctccattaaa ttcgttagac taaaattctt cagaatatta ttgttcaaaa
    14701 ctttcagttc attatcatta aagtgtctat tcaattgatt ggagaattta cttatattca
    14761 ttcctaaaat catatcttca attgaaaaga attctacatc ttctagatgt ggatttagtg
    14821 ttccaacaat aaaaagaata ttgttctctt tacgaagctc cgataaatag ttttcattca
    14881 ctaaagagta atagtcacac gtttctatga caagatcagt atcccttgga aagctatctt
    14941 caagtatctt ttttaattta aacgaagttc ctaatccgct tgcacaagaa cagacaatca
    15001 tatccttctt aatatttgat gattcataaa tataatccac attttgattt tcttttactt
    15061 gttcaagaat ctgtttaagc ggtaaatcta ataatatctg atttgcaaca tcaatagcca
    15121 ttcttgttga aacattgttt agtagtccga attttttttg agcgtctagt tccaaattta
    15181 gataaatttt ctccagtgaa cccatatcaa caagtaaaat aatttcttca tatccggtac
    15241 actcttgtaa gtatctatta attttgtctg caatctcact acttgaagtc attagtggca
    15301 tatcaatggc gtcgtatata tatctctcaa cgatcctatt agcagtactt gctatacagg
    15361 ttgccgttag atctccatga gccaaaatca gtgctaaacg tttttgctga aattctttac
    15421 tacacattaa cttaaataaa ataaccaaaa catttttttg aatttttgtt aaataaatat
    15481 cccctatttg aataaaacga ttgactaatt gaacttctcg actacaccaa ctattaatat
    15541 cattgatgaa ggaatataat ttatcgtccg atgttaattg gatttgataa atccaagaat
    15601 tcaaaaagat agacgttatt tgaagataat aatagtcaaa ttctatttga aaatctctct
    15661 ctatttcctt aacatactgt ctaaatcgaa tctcttgata ggtgggatat gttaaagctg
    15721 aattattttg gatatcaaca ttcttttgtc taaaatatct atcatatttc tcaaaaagct
    15781 gctgcttatc agtgtctttc ttccacgttt gataaagata ctctataagt tcgttgatat
    15841 taaaaacttc gtctactttt tccaaatcat ccatttgaat atattttaat tcattctgtc
    15901 ttttcataac cttcatgccg ttgaaattca cccattgtgg taaatgatac atctgaatat
    15961 aaagttcttc caaatcatct aagaaataaa aggcattggc acaggtcaat tgaatgatat
    16021 ttttcaaatt gccaacattt tcactaaagc gatagtttaa taaaaaatct aataattgtt
    16081 gagatatcag tattttcttt gctagtcttt cttcttctga tttaaaaaat atcttgatta
    16141 actgttttct ttcataaaga gaacgactgt ctaatgttgg aagtgttagc tttacaggta
    16201 ttcttctcaa caaagttgat aatagtttat cctcaggtgg ttctgatgtt gcaaatataa
    16261 tccagcaact tgatgtgtac cagttttcat tatcacccat ccgatgaaat ttcctcgtat
    16321 ccataaactg aaaaagtttc tcctgacatt cattgctcaa tgcatgaatt tcatctaaaa
    16381 ataagactcc attattagct aattctgcta aaccctttct tccatcttcg gctcctgtat
    16441 atgcaccttt tacatgccca aaaaaattgg acaagaaaag ttctggatta ttggcatatt
    16501 cactacaatt aactgaaatg aaagatgcct tctcttctat ataattattg gccaacaaat
    16561 ccttatacac ataatttgct aaatagcttt ttccagttcc agtctcgcca tgaagtaaaa
    16621 tgggtaagcc atttggcgga tagtagattg ctgctttaat ttgagcaatt acatttcgca
    16681 gacttccttg acttccgata accctttcta ttccaaccct aaaagagcta tcataccatt
    16741 tttccgcttc ctctgaagag ctaaaaattt gttgatttgg aactttctcc ggtaaagaaa
    16801 agaagattac tggacgagta ttgatttttc caaattctcc atcttttacg aattcattca
    16861 aatattgaga gacaatatta cgactaacat ttaatttttc agatattttc tgtgctgtat
    16921 tgttccccca tttattttta atctcagagt tctctatgac ataattgaca atgcgttctt
    16981 ttaattcttc catcacagca cctcctcgac actattcgaa ttttgccgac agtatttttc
    17041 cataaatatg acttgctaaa aaggctttgt ttagatcatt caattggaac gttgcttgtt
    17101 ttgcttgatc cgctaagacg ttgaaaagat actctggcga aatcgcatac cccaaaatat
    17161 caacgattgt tgcaatcaga tcttcttttg attcttcatc tgaaagtaat tcacgataca
    17221 acatcgtttg tttgcttact gtgtcatatt cctctaagga ttcatctgct aaaagaacca
    17281 cttgttccaa caaacggtcg gataaatatt tatagaaaat cagccccaat aaataatttt
    17341 tatattctga cgcatccatt ttactacgga gattatctgc cgcactaaat aacttctgat
    17401 ttaattctgc acccaaaaag atacactcct atctcttatt taaagttgct atataccctc
    17461 ttattttagc atactcagtt ttagaaaaag caaaaaaata aagaaactta ttcttgataa
    17521 caagctacgt gacgtatatc cctaacacaa aaatagccat atcctttggt ttggatacgg
    17581 ctatttgata ttactcattc aattatcaaa tcacagtagg tgtgaatctc atcgggatcg
    17641 gcaatatcta cttctgatta ggatcaaagg tgattttctc aataaaggtg tgatacaaag
    17701 ctttaacttg cttcttctca ctctggataa gaaagcaatc caaactagtc aatatctgtt
    17761 ggacatcttt gacttgaatc ggttcccctt gttgttgaaa gatccctaag atttcattct
    17821 ctcgaatttg taactgtctt cgtttttcag tcaattcatt taaacgatct tttaacatcg
    17881 gaaacaattc gggactatct tccaaagcag cttcctgttt ttgctctaat agttagattt
    17941 tgcgtaccat tttcttcttt tattttcctt cgattgctga ttttaatata gtctaaagga
    18001 aatttatatt tattgtattc tttataactt caagagaact tcgtttgagt attactgtat
    18061 ttttttaatt ccataagaaa attagttatt acctgccacc taatcagcaa atctgaacct
    18121 gagtcaatat aattaatatt attttccatc tccaacattg taagtactgt tggtgttaat
    18181 atagggactt tgtacaattg tatttttttg attttatcat ctgcacaaag gagatttttt
    18241 aaatctaatc cttcttttat ttcaaaagtt gaatttttta aatctataag agtaaaacca
    18301 attccttcat actgaatttc tgaaaatcga atttttctcc cagttgatag atcaaggggc
    18361 agaaaacctt ttattacatt gtgagtgtca ccatcattta caatgtcatt aggaattttg
    18421 attttagaat tctgtggagc acctattgga agataataat tcattataat tttgtagtct
    18481 tcatgaggaa ataaagtact tttaggattg ctaagatatt ctcgtaccga atctaagaat
    18541 ggcttatcca ttgaatcttc atccccattt aaactaaaaa acattcctac aattgctttt
    18601 gcaactctaa gtgaattcat tttctttatt gaatgtgtta aatcagactt accattcttt
    18661 aaacttgtat tgttataaag gaaattttta ttgtcttctg caaatctaat atattcctca
    18721 acatactcac taccaaaaaa actattacat ttactacata acg
//
LOCUS       DAFTHM010000048        18708 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFTHM010000048 DAFTHM010000000
VERSION     DAFTHM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.048"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            165..1643
                     /locus_tag="L7C88_001637"
     CDS             165..1643
                     /locus_tag="L7C88_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558458.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            1920..3980
                     /locus_tag="L7C88_001638"
     CDS             1920..3980
                     /locus_tag="L7C88_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBP9558459.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRREESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            4063..4632
                     /locus_tag="L7C88_001639"
     CDS             4063..4632
                     /locus_tag="L7C88_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9558460.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4807..5613)
                     /locus_tag="L7C88_001640"
     CDS             complement(4807..5613)
                     /locus_tag="L7C88_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558461.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5751..7265
                     /locus_tag="L7C88_001641"
     CDS             5751..7265
                     /locus_tag="L7C88_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBP9558462.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(7668..8651)
                     /locus_tag="L7C88_001642"
     CDS             complement(7668..8651)
                     /locus_tag="L7C88_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBP9558463.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(8656..9303)
                     /locus_tag="L7C88_001643"
     CDS             complement(8656..9303)
                     /locus_tag="L7C88_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBP9558464.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(9388..10020)
                     /locus_tag="L7C88_001644"
     CDS             complement(9388..10020)
                     /locus_tag="L7C88_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBP9558465.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(10036..10587)
                     /gene="coaC"
                     /locus_tag="L7C88_001645"
     CDS             complement(10036..10587)
                     /gene="coaC"
                     /locus_tag="L7C88_001645"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBP9558466.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(10584..11321)
                     /locus_tag="L7C88_001646"
     CDS             complement(10584..11321)
                     /locus_tag="L7C88_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBP9558467.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(11318..12307)
                     /locus_tag="L7C88_001647"
     CDS             complement(11318..12307)
                     /locus_tag="L7C88_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBP9558468.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            12565..13107
                     /locus_tag="L7C88_001648"
     CDS             12565..13107
                     /locus_tag="L7C88_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9558469.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            13124..14209
                     /locus_tag="L7C88_001649"
     CDS             13124..14209
                     /locus_tag="L7C88_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558470.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            14221..15027
                     /locus_tag="L7C88_001650"
     CDS             14221..15027
                     /locus_tag="L7C88_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9558471.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            15028..15855
                     /locus_tag="L7C88_001651"
     CDS             15028..15855
                     /locus_tag="L7C88_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9558472.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            15852..16925
                     /locus_tag="L7C88_001652"
     CDS             15852..16925
                     /locus_tag="L7C88_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBP9558473.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRK"
     misc_binding    17197..17424
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17483..18613
                     /locus_tag="L7C88_001653"
     CDS             17483..18613
                     /locus_tag="L7C88_001653"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBP9558474.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
BASE COUNT         6160 a         3251 c         3749 g         5548 t
ORIGIN      
        1 ataaattttt ccattttttg caatattctc aaaaaaaaga taaaaaatga gaataactga
       61 tgaaaaaaca agcataatcc atcataaaat cagtataggt gaaaagatga actttcatct
      121 gcatatcaag taattggtat gaggcatttt ttgaggtgta ggatatgaag ttggattacc
      181 ttatagaaga ggaagataga gaaaaactgc tgctagctag atatttagaa tttgagaaaa
      241 agaattatgt agtgctgcct aagttatatg aaacattagg tttgtctaaa tttaaaacaa
      301 gaaattatat catagaatta aataaagaat ttactgaatt caaaacaaag ccagagatcc
      361 aaatttcaga agaagcagag atccatgtcg aacgtctgaa tttgacggat atcaaaaatt
      421 taagaagaat ctactttcaa cgatcaaaaa ttgctcgact gttaacggag atcgtggatt
      481 caaaagtaac gatcgaaaaa tttgcagaga atcatttttt aagcatatca agagcctatg
      541 taaaaagaag agaattagtc tcttttcttg aacagcatca aataaagtta aagaaaaaca
      601 tattagttgg ggaagaaata aacatacgga acgtattatt tggggtatat ttcggggtct
      661 ttaatggttt ttctatgcca tttagagaaa gcgtcatgaa tgaagcaaag agtatcgtgc
      721 aatattttga atatctgttc aatttaaaac tgtctgcaac aaaacgaatc aaattcaatt
      781 tgctaaccac tattagtttg ttgagggcct atgggaatca accaatcgga aaacgtttct
      841 tttcagatga atactttaag agctcagaag gaatgaagat catcaaggat ttatcacata
      901 tttcttttct tcatatccct aaagagcaga tcattgatga gatttcttat atcatgttgt
      961 ttttgatcac ggaagaagaa tttgaattag atggcgcatt tggacttgcg gaagctcatt
     1021 ttcatgatat ccacatgatt agtcaaaaaa tgtcagtgga attgattgat caattaccat
     1081 tttcgattga aatctctgaa gaagaaagac tatatatacg aaaagaactt cgtatgggta
     1141 tgatgcatgt caatcgaaaa aattggatat tcgactttga gatgactagc tttacgtcta
     1201 aaaagcagct acagtttttc ttcgagacgt atccaatatt cagtacagca atccaaaagg
     1261 tcatacaaga gaataaacgc tatttcttgg gaaaagatga acgtttcatg attcgcttat
     1321 tttatgatta tctcttttta ttggtcggta tttgtccggt atcatatttt gaagcaccga
     1381 ttcatgtctg tattgatttt tcgcaaggat ctgcttatac cgattacatt atttctcaag
     1441 tgaaaggatt taaaaattac aatattgtga ttgagagtcg aatcacttct cgtacgaata
     1501 tttatttatc tgattgttta cttgaaaaat ttaataaaga acagataatt tggaaaaatc
     1561 caccgactcc agatgactgg gaatattttg gaaataccat catcagagaa aaaaatagac
     1621 atttaactga aaaaatcagc tagtatttat ggatggcagc tttgtctcac atatttatta
     1681 gctgatttat gtttttttca aagaaaaggt aactagatat aactagatat aactagatat
     1741 attacttaac aaaattaaaa agtacataag ttattattcc gattttcttg aaacaataaa
     1801 aaatcaaaaa aaatactctc ctaatagtcc atcttctttt gattttattt atataatgaa
     1861 atcatcttat gaaaattact acttcatgtt tagacaagag tagggaggac taagaataaa
     1921 tgtgttcaaa aagacgttca aaacaactaa ataaacacgc ttgtcgttta gataaggaac
     1981 ggtcgtgttc tgaaaaacac tacgttaagt ttatgatgcg cacgatgctg atcagtttat
     2041 ctgtaggtgt ctatatgcat gtacccgttc aggcaacgac acaaaccatc aaggtcgtac
     2101 gtacctctgt ttctgagacc actgattccc ctatcactat tactcatact ttcactgatg
     2161 caaatggaaa acagctactt cctgcattga cttcctataa taaagtcagt tatcctccaa
     2221 cgataaacca ctactggtta attcctaaca aaacattatg gacatcggaa accggaagca
     2281 gtgtgccgct ttctatcttt tccgatatga ctgatcctac aaaaggtgat cagttaaaac
     2341 agatcactga tattttgaat catgctttga cagatataaa ggacggtgga agcgcacaag
     2401 tttcttatgt atatgaaaaa gattattcac agtttgaaag aaagaaaatc gatgttctgg
     2461 cagggacaaa agtttcgata tctgatctgg tagaaaggct gaagaacgca gatggaacac
     2521 aaggagatat gtccaaagta atttcaaaca atgggaatat cgtggatacg actaatacag
     2581 gaacatctac tatttccttg tcctattttg atccaattgc tttaaaaaca atgactgcat
     2641 ctgctgtgat ccatgttcgt gctgatcaaa cagctatcaa aggaaaagat cttcacttaa
     2701 gaacaggaga gagttacgcc cctaaagatc ttgttgaata tgtaacaaaa agcgatggaa
     2761 cttcaggaaa taaagaagaa atcaaaatga acgggacagt agatactaca actccgggag
     2821 aatatcccgt tgtattaact tatatagact cgaaaacatc aaatgtggca gaaacaacag
     2881 ctgtagttta tgtagaagca tctgctgctt catcgactgt catcactcat tttatagata
     2941 gtcaaacaaa taaagaactt caagcagaaa cacatatgag tagtgtaaat cgtattcctg
     3001 atttgcgcct acctgctgaa ttttctgatc gagtgccaaa tatagattta tcgacttatg
     3061 aacaaaatgg gaaagtcact tctatttctg attggatgca agcaaacgga ttagacagaa
     3121 aaagtcactg gtcggagatc cttgaagtac ttcactcaga actgatgaat aataggaagc
     3181 aatcaggagg ggaaattacc tttacttatg tttatatacc agacaatcgt tcattagaag
     3241 gtcatgatct tattgttcat ccaaacgaaa aaataaacaa agaagagttg atccaatcag
     3301 caacaaattc cttaggtaaa cccgtaccgt taaaggatgt atcggttaca atcaatgaag
     3361 taccattgga ggatggttat ttgaccaaac aaacaggtga ttttacgatt atgtatagtt
     3421 atcatgaccc gtattcactc caagaactcc atgctcagtc actattacat gttttaccat
     3481 taaacaaaca gatagatcaa aaagaacaaa aaagacgaga agaaagcttg tcagaaaaaa
     3541 aacaacaaat ggctcatgca gtttctccaa cagggaaagt aaaacaaaca agaagcctag
     3601 agttagcaag aatatctaga aaaatctcag aatctaataa aacgataagg caagaagctc
     3661 atttggcccc acaagtttct ggattggaaa atgaaatttt agagcctaaa ataaaacaac
     3721 aatcagaaaa agaatttgtt gctaaacagt cggaagatca gaaggaatca gatgaccaga
     3781 aggaaacgaa gaaaaaacgc ttgtcaacta ttgattccac cgatgagcat ctgcagccgc
     3841 aagtaccact tcctagtccg ggaacacccg cacctggtgg aggtattcct tcttctgctt
     3901 taggagattt catgcgaggt atggcaggaa catgggtata cgctaatcga aatgaatttg
     3961 acgcagatga ctggttctga tttatatctc tatctgttat agtcaaataa gtagctgagt
     4021 catatgttat ttggcataat ggagacgagg agggatagaa aaatgttaga taaaacgtta
     4081 ccttacgcag aaatctggat gacaagacca cttcaacaaa atgttccaat cacgccttta
     4141 gcggaaggtt ttgaatttcg attttatcaa aaagaagatg aatctgcttg ggcggagatt
     4201 gagacttccg ttggggaatt tcaaacgaca gatgaagcac ttgagtattt tcaacaaaac
     4261 tttgctcctt atcctgaaga acttgaaaga aggatgtttt ttgtagagac aaaaaaagga
     4321 gaaaaagtag caacctgtac cgcttggcga aaaaaatcaa gagagcaagt gtatccggtt
     4381 tttcattggt tagcagtgaa accagattac caaggaaaag ggctcgcaaa agcattgact
     4441 gccagagtct tgcaagaatt tcctaccctc catacggacg gaccaatcta tcttcacaca
     4501 cagacatgga gccatcaggc gattgctctt tataaaaaaa tgggttttac ttttattgct
     4561 gaaaatctag acggcacacc taatccagat tatgaaaaag ttatgcaggt tttaagtaaa
     4621 ttagataaat aacgaaatgg tgaaataagt cctcagtatt gggataaaaa acgaaatagt
     4681 cattcctcat atcttacttt tttgagttaa tactatcgga taactaatgg catgccatac
     4741 attcaaaaaa gaaggggcag tgacaaaagt attgtcactg ccccttctct tgttttttag
     4801 catgttttat cgtttgattt ttttaggaat aaaattcttg atgaacgtaa atttttggta
     4861 atcgtttcga ctatagaggt aaccaaatac actgaaaaca actgctccaa taaaattaac
     4921 aaataaatcc ttcatagtat ccatgattcc cacgtctaag taaccatttt ggatgattgt
     4981 tttatctgtt ttaccatctg cattttgact ttcaatgatt gtccgagtga tatctggaac
     5041 atgatagaca gtgtttccgt ctttacttaa ctccacacta ttgatttgct ggatgatcgt
     5101 atctttttgc atatcgaatt gcagtaattt atctgctgaa aattccacaa actcccacat
     5161 aacaccaact gtcatcgaaa aacagaagga aacaactgct agtaataaag gagtcaagtt
     5221 catggttttt gtatttttat tgagcaaata aacaagggaa aagccgacac ccccagctaa
     5281 aaatccgctg aatgcatgta gaaaagtatc ccacattgaa aaatagccat aaaaatcact
     5341 taactctcct aaaactgttg aactaaaaat aaaagataac aaaatgattt ctagcatatt
     5401 tggaatctgt atctttaata tcttttccag aaaataaggg atttcaaata aaattaatgt
     5461 cagtaataaa agcattgtat ttccccagtg ttggttccag acctgatcca ctagcataat
     5521 aacgacgatg atacgtaata aaatatagat tccgtttgtg attctacctg cagtttttgt
     5581 actgttcgta aaaaaggttt tcaaatgatt cataaaataa ctccttcatg tatatcctta
     5641 attatactaa gaagcgtgtg tttaccaaag ctatatgact taaagaaaaa cagagttgat
     5701 attgtgaaaa aaatcactta atatagtata aggagaaaag ggggatacaa atgaaaaaat
     5761 tagttgctgg tttattaaca gccgttgcac ttcttgctat gagcgcatgc ggcgcagatc
     5821 agaaaaatac agcgcagaca agttctagta cgaaggaatc tgccgaagta tcatcaggcg
     5881 cttctgaaca agtatataca gatccaaaag aaatgaaaga atcttatgat gtcgtgatta
     5941 ttggagctgg tggtgcaggg atggcagcag ctatcgaagc aaaagatgct gggttgaatc
     6001 cagtaatttt ggaaaagatg cctgttgccg gaggaaacac atctaaatca tcaagcggta
     6061 tgaatgcttc agaaacaaaa tttcaaaaag aagaaggaat caaagactcg aatgatgcct
     6121 tctatgaaga aacgctaaaa ggtggtggag gaacgaatga taaagaaatg cttcgatact
     6181 ttgtcgatca ctctgctgat gcggtcgatt ggctagatca aaacggtatc aaactggaca
     6241 acttaacgat cactggaggg atgagtgaaa agaggacaca tcgtccgtct gatggctcgg
     6301 ctattggtgg atacttagtg gaggggttat tgaataacgt ccatgagcgg gaaatcccta
     6361 tttttgtcaa cgcagatgtg acagacatta agaaaaatgg ggaaacggtc aatgaagtga
     6421 ctgtacatgt tcaaggagaa gaaccaaaag aggtcaccgg aaaagcaatc gtagttacca
     6481 caggcggttt tggtgccagc aaagaattta ttgaaaaata tcgtcccgat ttagctgatt
     6541 atattacgac aaatcaagaa ggatcaactg gagatggtat caccatgatt gaaaaattag
     6601 gtggacaaac cgttgatatg gataaaatac aaattcatcc aactgtgcag caggatgagg
     6661 gggtcttgat tggtgaggtt gttcgcggag aaggagcaat cttggtcgat caagagggga
     6721 aaagatttgt caatgaaatg gatacaaggg ataaagtatc tgcagcaatt acagcattgc
     6781 ctgaaaaatc agcttatttg atttttgacc aaggcgtgcg tgatcgtgcc acagctattg
     6841 aattttatga ccaaaaagga tatgtcacaa ctggaaagac aatggaagaa ttagcagaaa
     6901 aaatcgattt accaaaagaa acactagcaa aaacagttga tggatggaat acggatgttg
     6961 cggagaaaaa agatgctcaa ttcaaccgtg ccacagccat ggaacatgac ttatcgtctc
     7021 cgaattatta tgcgatcaaa atcgcaccag gaatccatta cacgatgggc ggtgtgaaaa
     7081 tcaatacgaa cactgaagta ttagataaag aaaaccagcc aattaggggg ttatatgctg
     7141 ctggtgaagt cacaggtggc ttacatggaa acaaccggat cggtggaaat tcagttgcgg
     7201 agatcattat ttttgggcga caagcgggca tacaagcagc tcgatttgct tcggaaaatg
     7261 aatgaaatag aacgtaaata aaaagaggtt gtgaaatcag cgttttgagc taataccgag
     7321 ggtcagctga ttgaacactg tttagtgaag aggttgtgaa aaagctgccc tgcatcaagt
     7381 aataagaaca gccaagtaaa aacagcttct tatgttttta acttggttgg acttattacc
     7441 gcagatgcaa gcttttgaac accgtttatt cggaaaaaga gcgtgggaca aaagtaaaga
     7501 acacttttgt ctcacgctct aaacacgtat aaacggcgga agcagaagaa attccttcgg
     7561 aaataagctg aaattcacaa aaatttgaaa agcaattttc gtgaatttct tcttatttct
     7621 tggagttaaa cgcttctgtc ccagcctctt ttttgatcag catgatttta ttcagttatc
     7681 ttcaaaatga tttttccgat gtttttgttt gcttccatat attcatgcgc ttgtttgact
     7741 gcgctgaatt ggaatgtacg gtcaatgatt ggccgaatct tgccattttc tagaaaaggc
     7801 ccagcttttt gcataaaagt ttgtgcgagc tctgctttat actgatcact tctaggtgtc
     7861 aataatgtac caagcagttg gacacgtttc ccaatcaata caccaaggtc tatctcaggc
     7921 acgatggtcc cacctagcat accaatcaag acccaacgtc catcaacggc tatagaagct
     7981 aaattctttt cccagtaaga agcgccgatg aaatccaaaa taacatcgac tccccgacct
     8041 tcagtgattt ttcgtacctc ttcttgaaag tcttgttttt tatagttgat caattcatct
     8101 gcaccaagtt ctttacaaaa ggcgagtttt tcttctgatc ctgcagtaac gatgattttc
     8161 gcgtgagaaa gctgtctagc taattggatc gctgctgttc ccacaccact tgctcctgca
     8221 tggatcaaga cagtttcgcc ttcttgtaat tttccaagcc agtaaagtgt ttgataagca
     8281 gtcaaaaaaa cttctgagat tccagcagca gaaacatagt ctagcgtatc agggagaagg
     8341 attgcacgat cggcaggcat cacagcatat tcggcataac cacctagatt gactaatccg
     8401 tatacttttg tcccaggagt aaaagtggag atatcacttt tattctcaac tacctctcca
     8461 gctacttcga ctcccaaaat agggtaggga ggtttcaaag agactgattc tcttttcata
     8521 atatctgttc gattgacagc tgctgtatgg actttgatca gtaattcgcc ttgttttggt
     8581 ttaggaacag gcacttcaat ttgttctaat acatctacag aaccaggatg cttgattgaa
     8641 atggcacgca tggatctatt cctcctttgc ccattcttgg aatgctgtat tcaactcttt
     8701 gctaccttca gaaagtacta gagtcgtacg agaaatatcc gtttcttcca ctagagcggc
     8761 aagtacagca gcaactgtag agcgagtgat cgtttttgat gccttctcat taggcttagt
     8821 taattgaatg gaagtaactt cttcatcgtt agtcaatgtg actggttgaa gaatgacaaa
     8881 atctaagtta gttcgtttca gccattcatc tgcataatgt ttagtaatat aataatctgt
     8941 catggactca ggccattttg ctggttcatc tgcataaaca gcactgacca tcagatagcg
     9001 agagacatgc gcattttcag ctgcgatcac tgttttgatt gcgccatcca agtctacttg
     9061 cagaagattc tttccttgag agccggcagc aaaaatcaat acatcgatgc ctttgaatgc
     9121 ttcggtcatt ttttccacgg accaagttaa atcaaaagag acatacgaaa cattctcttt
     9181 ttttactaat gtttgggaag caacatctct cacccctgca aaaatttcat gggaacttgg
     9241 agctaaatct tttatcaggt gtcggccaat ttgtccgttt gcacctacaa caaaaatttt
     9301 catttggatc atcctttcga cgtcaaatct ttccattcaa tagtaacacc aaaagagaaa
     9361 aaaatcagag atcggctacg atgactatca gttagtaaga gaagggtgct tgaagtatct
     9421 taacaagaca ttgcatactg ctgcagtcgc aagacctgcg acgattcctt caggtatacc
     9481 acttgtaaaa ataaccgcta gaatagctga ataaacagca tttaaatttg ttccgatgac
     9541 tttggcataa tcttgctgga ataaaaagta gatcatattc atcactaaaa tcgtattggt
     9601 caatgaaccg gaaagtccag ctaagaataa agaaacggaa tctgcttttt gtttcattag
     9661 tttgcgcaga cctttataaa cgaaataagg aaccacccca atcaagatgc gaggaataaa
     9721 cgcgatcagc aaggctttcc agcttccatg ttctgttccg atgactggga taaacggaga
     9781 aaagacaaaa gacaaaggtg tttggataac tgtgctacgg atcatgctga tcagtccaaa
     9841 tgtaccgcca agaaaagcac ctagtcttgg tcctaaaacg atcgaagcaa tgattacagg
     9901 aatatgcatg gttgttgcat tgattggacc gatagggata aaacctaaag gcgtaacagc
     9961 taataaaatc aaaatagcta aaaacatcgc agttaatgta aagttttttg tatttttcat
    10021 aagtactcct tttttctaag catttctttc attaagagtc agcatgacct gttcgatgat
    10081 cgtctgaata tcagctaagg caccttttcc aaaatctcca caagctaaaa gagattctct
    10141 tggttcaatt tcctgatagc cgacagatct caatgtttcc agattacgct gagtgatcgg
    10201 gttttgatac atattcgtgt tcatggcagg ggcaatcaat tttggtgttc ccactggaag
    10261 cgccattgcg actgttgaaa gaagatcgtc tgcaatgccg tttgctagct tgccgataat
    10321 gtttgctgta gcaggcgcga tgagaaacaa gtcagcttgt tttgctagtt cgatatgatt
    10381 gattacctgc ggatttgatt cttgcatgac gtctgtatgg actgcgcgct tcgacagaga
    10441 ttgcaaggtt aatggcgtga taaaatgtgt gctgctttta gacataatca catctacctg
    10501 ggcacctaat ttgacgaatt gacttgtaag atcagcgctt ttgtaagcag aaatacttcc
    10561 agtaacgcct agtaagatct ttttcatttt gattcctcca gtctaatttt ctcagtaatc
    10621 aatgcagcaa tctcagattt actttgagct tcttccactg ttccatcttt agataagaga
    10681 tagccgtggt gtgtctcgcc atggatttcc gtcaaatcat ttgcgaaaat aaaatcagtt
    10741 ttgttattta tcagactatt ttttgcgact gccagaagag attcctttgg tacatctact
    10801 aatagtttga aaccaatgat ttttgctttt ggctgccatt cacgtagata agaaatgatt
    10861 tttggtgttt tcttcaaaac gagcacaaga tgctcggtgt tagaagagat ctttgaaaca
    10921 gtggtatctg tctgttcatt ttccgcaaac caattgtcca gttcttcttg cgttgaagaa
    10981 gtgggtaggt tttttgccag ctgttcttct gaaaaactaa aagcaggagt aaaatcactg
    11041 actgccatac tgtggataat cgcatcgtag tgttcttttt tcgttagttc ttctaattgt
    11101 aaaaataagt ccagtgcaga ttcgatcgta taaatcgtta tattggagtg tcttttcggt
    11161 ttcagtgctt gtttcgtagt cacgtaatcg attgtggtat ccggattggc agctaaataa
    11221 tcagctaatg cttgccctaa tcgtcctgtc gaatgatttg taatagcacg tacttgatcg
    11281 attttttcag tcgttcctcc agctgtgatt agaatcttca tttatggtca cctacattta
    11341 ctagtgttct tccttggtgt gttccagcaa gtagtttaga tgctgtttca ggcaattgat
    11401 ccagagtaat ctcttggacg accagttcat ctgcaatctg caaatccgcc atctgttgcc
    11461 ataaagaaag acgttgatct attggtacat tgacagaatc aattccaatc aactggatgt
    11521 ttcgcagaat aaaaggcaag acagtcgcgt ttagtttgat tcccccagca ttgccacata
    11581 aagctactgc accgttataa gagatcaatg gaagaagact gcttagctgc tcgccaccta
    11641 ctgtgtcgat gacatagtcg atttgctgtt ttcctaaagc ttttgttgtc tctggcagaa
    11701 attcatcagg tcgtacgact tgcaaagcac ctagactttt tagccatgtg acagactctt
    11761 cttttctgga aaaggcaatg attgactgga atcctagttt atgtaacagg gctatcgctg
    11821 tactgcctac accgccagaa gcaccagtaa cgacaacttt tttatcggag gtcatacctt
    11881 gacggattaa agcgttcaca cacaacatag cagtaaaccc tgctgtacca aggatcatcg
    11941 cttgacgcag cgtcatattt tttggtagag gaactaacca gtctcctggt actttttgat
    12001 attggctata accgcctgga tgggtgacgc caagcccaaa accagtagca agtacaagat
    12061 cttcttttga aaaacgtgga ttgttacttt ggacgacagt tccggataaa tcaatccctg
    12121 gagtcatcgg atatgttcgt atcacctgac cagactcgct cattgccaat gcatctttat
    12181 aattgacatc agaataggca atttttacca agacttcatt ttcagccaac tcagtaaatg
    12241 gcagatcact gattgctgta tggaaaacag gttcctttat tacctgaaaa gatcgaaaag
    12301 cgttcattcg tgagacactc cttttaaaat tttcttttat cataccataa agcctactct
    12361 tttattcttg ttcttccgta aatttagaca aaaattaggt gaaaaataaa gaatcaaaca
    12421 actagaattt attccaaaag ataaagaaat attcagcaaa aaaaatttta caaagggttg
    12481 cctttttcaa taaatttcgt atactaatac gagtggtagt aaacaggaag tttactatta
    12541 gaaaacttcg attcggagga aattatggaa attggtgaga agttaagaaa tttgcgcatc
    12601 caaaagaatt tgacacaaga agaactaggc gaacgcacag atttgtcaaa agggtatatt
    12661 tcccagttgg aacgagattt aagttcacca tcaatggaaa cattcttttc tattcttgaa
    12721 gtcttaggtg tgactccaga agaatttttt catcaagaag cagcgaatct gcaagtggtt
    12781 tattcaaaag aagatcatac ggtttatttc gatgaagaaa acgggtatga attggaatgg
    12841 ctcgtggctg attcgaatga aaaagaaatg gagcctgtct tgctgacttt tgaaggtgca
    12901 ggagaatata agacgtttga accttcatta tctgaaacgt ttatttttgt attagaaggg
    12961 gaattagagt taagcttagg agagacggtc tatgtggcaa aagcaggaca gtcgatctat
    13021 tatcaagcga caaaacaaca tcaattaagg aatcatctca aaaaacgaac aaaagtattg
    13081 attgttgcaa cgcaatcata tttgtaatat agggggtaaa aacgtgggga aaccaatcat
    13141 ttcatttgat caagtagtga aacgctatga tgatgaaaca gtattaaaaa aagtaagttt
    13201 tgagatcgaa caaggaaaat tttatacact gcttggtcct tccggctgtg gtaaaacaac
    13261 gatcctacgt attatagctg gattcaccga agctacagaa ggggacatct attttgaagg
    13321 gaaacggttg aatgatttgc cagctaataa gcgacaagta aatacagtct tccaagatta
    13381 tgcacttttt cctcatatga atgtttttga taacgttgct tttggattga agatcaagaa
    13441 aatgtccaaa tcagatatcg aaaagaaggt aaaagatgct ttgcgtatgg tccagcttcc
    13501 tggatacgaa aaacgggaga ttagtgaaat gtctggtggt caaagacagc gtgtagcgat
    13561 tgcacgagca attgtaaatg aaccgaaagt attgctatta gatgaaccgt tatcggcgct
    13621 tgatttgaaa ctacgtacag atatgcagta tgaactgcgg gatctgcaac aacgattagg
    13681 aatcacgttt atttttgtta ctcatgacca agaagaagcg ttggcaatga gtgatgagat
    13741 ttttgtcatg aataaaggga aaatcgtcca aagtggtaca cccgtagata tttatgatga
    13801 gccaatcaat catttcgttg ctgattttgt tggggagagc aatatcgtgg acggtgtaat
    13861 gatcgaagat aatctagttg agtttgttgg taagcaattt gaatgtgtcg atggcgggat
    13921 gcgtctaaat gaaccagttg aagttgtttt acgcccagag gatttgacga tcacgacacc
    13981 agataaagga aaactagtcg taacggtcga tactcagctg tttcgtggtg tccattatga
    14041 aatcatctgt tatgatgaac agcaaaatga atggatggtc cattcaacga aaaaagctaa
    14101 agaaggaagc aaagtaggat tggcctttga gccagaagat atccatgtca tgcgtttcaa
    14161 cgagtctgaa gaagaattcg atgcacgtct tgacagctac gaagaatagg ggggacaaga
    14221 atgaaaacaa tgcgcaggat ctattccgtc ccttatattt tgtggctcgg tttattcgtg
    14281 atcgcgcctg tattaatgat catttatcaa tctttttttg atatgaatgg gcaattcacg
    14341 ctgaataatt atctatctta ttttacgtcg gggacatcgc tttctatgac gatcaattct
    14401 gtatggtatg catttttgat cacgtttttc acgctgatca tcagttaccc gactgcttat
    14461 tttttaacaa aactgaagca caagcaatta tggctgatgc tgattatttt gcctacatgg
    14521 gtgaatctgc tgcttaaagc ttacgcattt attgggattt tcagtgtgca cggcagcgtg
    14581 aatcatttct ttgattttat cgggatcggg ccgaaacaga tattattcac agacttcagt
    14641 tttctgttcg tggcaacgta tatcgagatt ccatttatga ttatgccaat tttcaatgca
    14701 ttggaagaga tgaatccttc tttgatcagt gctagtagag atttaggcgc gaatagcttt
    14761 gagaccttcc gacgagtgat ttttccgtta tcattaaatg gtgtgaaaag tggtgtccaa
    14821 gcagtattta ttccttctct ttctttattc atgctgactc gtctgattgg cggaaatcgg
    14881 gtgatcactt taggaacggc tatcgaacag catttcttgg ttacacaaaa ctgggggatg
    14941 ggttctacaa tcggtgtgat tttaatcatt gctatgttca tcgtgatgct cctgacaggc
    15001 gagaagaaaa aaggaggtcg ctcataaatg aaaaaattta aatggtcgta tctttattta
    15061 gggatcgtct ttttattctt atatgcaccg atcttctatc tgatttttta ttccttcaat
    15121 gaaggaggaa cgatgaacag ctttacagga tttacttggg aaaattatga agctgttttt
    15181 gaagatacac gtttgatcat tatcgtattg aatacgttca tgctggcttt cttatctgca
    15241 ttgatcgcca cgatcatcgg gacatttggg gctatgggaa tctattacac gaaaaaacga
    15301 cgtgcacgga cagcgttgtt gagcatgaat aacatcttat tagtctctcc tgatgttatt
    15361 atcggtgcta gtttcttgat tttctttaca ctactaggat tcggattagg ttttcagagt
    15421 gtattgcttt cccatattgc tttcagcatt ccaatcgtcg tcttgatggt cttgccaaaa
    15481 ttgcaggaaa tgaacgattc aatggtcgat gcggctagag accttggtgc taataatttc
    15541 caagtagtca aaaatatcat tttgccttat ctttctccag gaatcatagc tggatatttt
    15601 atggcattta cctattctct tgatgatttt gcggttacat ttttcgtcac aggaaatggc
    15661 tttacgacgc tctcagtaga gatctattct cgtgcaagac aaggaatcag tttagaaatc
    15721 aatgcgctaa gtgcgttagt tttcttgttc tccatgatat tggtcattgg atactacttt
    15781 attagtaaag aaaaccgtcc aaaacggctg aagaaaaaca gaagagtacg cgagggggtg
    15841 gcacggctgc gatgaaaaaa ttacaatctc tgtttttagg tattctcatc attattgcgg
    15901 tgctgctgct tggtgttcgt caacttgaaa aaacaagtgg catgagtgga gcaaaggtac
    15961 ttaccatcta taactgggga gattatatcg atcctagttt gatcacgaaa tttgaaaaag
    16021 aatatggata caaagtgaat tatgaaacat ttgattctaa tgaagcgatg ttcacaaaaa
    16081 tccagcaagg tgggacaaac tacgacatcg ctataccaag tgaatatatg atccaaaaaa
    16141 tgatcaaaga aaaactagta cttccattag atcattcgaa gatcaaagga ttaaataata
    16201 ttgatccacg atttttagac ttggattttg atccagataa tcagtattcg attccatatt
    16261 tttggggaac tttagggatc gtatataacg ataaattctt tgatgcaaat caaattaagc
    16321 attgggatga tttgtggaag ccggaattaa aagacagttt gatgctgatt gacggtgcac
    16381 gagaagttat ggggctttct ttgaatagtt taggctattc tttgaatagt aagaatatgg
    16441 cacagttgac agaagcagca aataaattga atcatttaac accaaatgtc aaagcaatcg
    16501 tggcagatga gatcaaaatg tatatgatca atgaagaagc ctccgtggca gtgacatttt
    16561 ctggcgaagc tgccgatatg atgtgggaaa atgaacattt acattatgtg atcccaccag
    16621 aaggatccaa tctttggttt gataatatcg ttatgccaaa aaccgtgaaa aataaagaag
    16681 gtgcctatga tttcatcaac tttatgctag aaccggaaaa tgcggcacaa aatgcagagt
    16741 atattggtta ttctacacca aatgaagaag caaaagcgtt attgccaaaa gacatttcgt
    16801 cggacgaaca attctatcca tctgatgaca cgatctccca tcttgaagtc tacaaagatc
    16861 taggatcgaa atacctaggc atctataatg acctattctt agaattcaag atgtatcgga
    16921 aatagcgaga aaataagcaa atttgcataa ctataataaa aaggacttag ttttgatggg
    16981 aaatttttca aaattaagtc cttttttatg tggttgaaac gggtatgatc attttaagga
    17041 agtgatctaa gatgaaagga cgactgaaca attatcatat tagaaaagct ttattgtatt
    17101 ccacaaacaa attactaaga ataacaaatt agtttttgtt tgttcttatt ccctattgac
    17161 ttttctttca aacatgctat tctaatttta ttctaatagt atccgatgag aaggaaagta
    17221 gacagaaaat ggttcaagag aggctttggt tggtgtaaaa agctagaagt tgactgtcga
    17281 aaatggcctt agaggatttt ttgtcgaaag gtaggcaaaa acgaacagtc tttcgttacc
    17341 aagaccactg attttattgt caggctgaga gaaagaatgt tttttctgaa aaaaggtggt
    17401 accacgagta taatcgtcct tttactagta tttgctagta aaaggatttt ttttacaaaa
    17461 aacaaagaaa agagtgagtg aaatgagcaa aaatagacca tttacagtag atcatgtcgg
    17521 aagtttctta cgcccgcaat cgatcaaaga agcaagaaaa aaagttcaag aaggcttact
    17581 ttcaaaagaa gaacttcgtg caatcgaaga ccaggaaata aaaaaattag tggaagacca
    17641 aaaagcagtc ggcatcaaag gaattacaga tggtgaattt cggcgtggat tttggcatct
    17701 tgatttttta gaagaactaa atggtatcga aggctatgtt ccagaaactg gatataatca
    17761 aacattccac ggaaaagcag caccagctta taatattcgg gtagtagata aattatcttt
    17821 caatccaaat cacccatttt taaaagattt tgcttttctg aaagaagtag tggaaacaga
    17881 tgatactttt gttgcaaaag caacgatccc tagtcccacg atgattttac gacaagagat
    17941 cctatctaat gatggttctt caaaaatcaa ggagatttat cctgatctat ctgattttta
    18001 tgaggacttg tcctctactt acaaagcagc gattcatgct ttttatgaaa aaggttgccg
    18061 ttacctgcaa ttcgatgata caaattgggc gtttctagct gatcaaacta aaagagaagc
    18121 acttcttcaa aaaggaattg atccgaaaga aatggcccat atttgtacag agattatcaa
    18181 taacgcactg gaagacaaac cagaagattt gacgatcaca acacatatct gccgcgggaa
    18241 tcacgcttct tcttggctgt tttccggtgg atatgaaccc attgcagaag agttgttttc
    18301 aacaaattat gatggtttct ttttggaata cgattctgac cgagcaggag attttactcc
    18361 tttaagacat tggagtaaca aagaaagtaa agttgtttta ggattagtta cttctaagtt
    18421 tccagatttg gaagatacgg agaaaataaa agaacgaata aaagaagcac aacaatttgt
    18481 accattggaa aatctaagta tcagtcctca atgtgggttt gcttcaacag aagaaggaaa
    18541 ccatttaaca gaagaagaac aatggaagaa aatccaatta ttgcagcaag tcgcaaaaga
    18601 agtttggcta taaaaatgtg aggcttggca aaaaaaagcg tcccaaaaag tcggcttttc
    18661 atggagtgga gaaatccact cttttttatt taccttttat attattta
//
LOCUS       DAFTHM010000049        18579 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFTHM010000049 DAFTHM010000000
VERSION     DAFTHM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.049"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            101..376
                     /locus_tag="L7C88_001654"
     CDS             101..376
                     /locus_tag="L7C88_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558475.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            389..2461
                     /locus_tag="L7C88_001655"
     CDS             389..2461
                     /locus_tag="L7C88_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBP9558476.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKRVQ"
     gene            2626..4512
                     /locus_tag="L7C88_001656"
     CDS             2626..4512
                     /locus_tag="L7C88_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBP9558477.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4524..5471
                     /locus_tag="L7C88_001657"
     CDS             4524..5471
                     /locus_tag="L7C88_001657"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBP9558478.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5491..6018
                     /locus_tag="L7C88_001658"
     CDS             5491..6018
                     /locus_tag="L7C88_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBP9558479.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6081..6734)
                     /locus_tag="L7C88_001659"
     CDS             complement(6081..6734)
                     /locus_tag="L7C88_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBP9558480.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            6866..7708
                     /locus_tag="L7C88_001660"
     CDS             6866..7708
                     /locus_tag="L7C88_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBP9558481.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            7866..8762
                     /locus_tag="L7C88_001661"
     CDS             7866..8762
                     /locus_tag="L7C88_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBP9558482.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8765..9478
                     /locus_tag="L7C88_001662"
     CDS             8765..9478
                     /locus_tag="L7C88_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBP9558483.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9498..10016
                     /gene="msrA"
                     /locus_tag="L7C88_001663"
     CDS             9498..10016
                     /gene="msrA"
                     /locus_tag="L7C88_001663"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBP9558484.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10013..10240
                     /locus_tag="L7C88_001664"
     CDS             10013..10240
                     /locus_tag="L7C88_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBP9558485.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10392..10943
                     /gene="lepB"
                     /locus_tag="L7C88_001665"
     CDS             10392..10943
                     /gene="lepB"
                     /locus_tag="L7C88_001665"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBP9558486.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11026..11526)
                     /locus_tag="L7C88_001666"
     CDS             complement(11026..11526)
                     /locus_tag="L7C88_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBP9558487.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11805..12203)
                     /locus_tag="L7C88_001667"
     CDS             complement(11805..12203)
                     /locus_tag="L7C88_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBP9558488.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12463..13323
                     /gene="ylqF"
                     /locus_tag="L7C88_001668"
     CDS             12463..13323
                     /gene="ylqF"
                     /locus_tag="L7C88_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBP9558489.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13316..14083
                     /locus_tag="L7C88_001669"
     CDS             13316..14083
                     /locus_tag="L7C88_001669"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBP9558490.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14139..14996
                     /gene="dprA"
                     /locus_tag="L7C88_001670"
     CDS             14139..14996
                     /gene="dprA"
                     /locus_tag="L7C88_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBP9558491.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15118..17196
                     /gene="topA"
                     /locus_tag="L7C88_001671"
     CDS             15118..17196
                     /gene="topA"
                     /locus_tag="L7C88_001671"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBP9558492.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17165..18541
                     /gene="trmFO"
                     /locus_tag="L7C88_001672"
     CDS             17165..18541
                     /gene="trmFO"
                     /locus_tag="L7C88_001672"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBP9558493.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
BASE COUNT         6469 a         3211 c         3868 g         5031 t
ORIGIN      
        1 aaatttctaa ctagcaataa acgatgaaac aatgaaatat ttttcatcca aaaagaactt
       61 tgctataatg atggaagttt gtgtatagga gatctggaaa atgagagaga gttttgaaca
      121 acaaaaaaaa ctgttgcatg atcgctatgg cgccctttcg atggatgacc gccgtcaaat
      181 actttgtaag ttgcgtaaaa gaaatatatt gatgtatcgt cagttggaac gtctgaaaca
      241 tgatctgctt cgtttggagt caaaacgtgt acagtgtgaa ttagagggga accaaacaca
      301 ggttgaagta gtcgaaacca aaattttaaa gaaaaaagaa caatttttaa aaatgcttac
      361 acaaaataaa aaataaaggg gatggacgat ggaatttgct gagttagtta ttgtatttgc
      421 agtaacgatc accttatcga acatagctag ccgcattttg ccaatgattc cagctccact
      481 gatccaaatt ttccttggag tggtattagg tctgacagag tggggacaat caatcgattt
      541 tgaacctgaa ttgttcttag ttatgattat tgcaccattg ttatttagag aaggagaaaa
      601 agcagatatt tcttcgattc tcaaaaattt cgggacaatt ttgttcttgg catttggagg
      661 agtcattttg acccttgtcg gggtaggtgc gacgttatca ttcctgttgc caagtgtccc
      721 acttgctgcc tgctttgctt ttggagcagc gttaggtccg acagatgcgg tagcagtcag
      781 ttctctttct ggacgagtga atatccctaa aaaggcgatg catattttgg aaggagaagg
      841 tcttttgaat gatgcatctg gtgttactgc cttccagttt gctcttggtg cgctgatcac
      901 cggatctttt tcagcagtaa acgcggggat gagtctagta gtttctagta ttgggggagc
      961 tttgatcggc tttttgcttg tctggttcaa acaaaaaata attcatttga tcgaaaaagc
     1021 atcagcacaa gatgtcacag ggtatctgct gatcgaactt ttgcttcctt ttctagccta
     1081 tgtattggca gaggcatttg atgtatctgg aatcattgct gcagtggcag caggtattct
     1141 ccaagcttct ggttttagga aaatctctgt gtttgatgca gaattgtcga gcttgtccca
     1201 cagtacatgg acaactattg cttttacact gaatgcatta gtatttatat ttttaggaat
     1261 cgaattgacg caagtgttct cgccagtatg gggagacggt ttatatccaa acggtctttt
     1321 attagcgatt atcgtattaa tctctgtcat gctttttgtg atcagattca tttctatcag
     1381 tcttttttat gtattcaaag atggcagtaa aaagttcaaa aaacagttga acgagatctt
     1441 gatcttaaca tttggcggtg taaagggaac agtcagtttg gctacgattt ttattttgcc
     1501 attttcaatc aataatatga tgttttacca gcggtctttg cttttgtttc tgacggcggg
     1561 tgtcatctta gtgactttgg tcatagggat cattgtcttg cctatgctga cggaaacaga
     1621 ggaagcgaaa agcacggatt tgaatgcttt gatgatttta gaagaggtcg ttgaagtttt
     1681 gcgaaaagaa ataaaggaaa ttgatcgtaa tacaaaagaa tttttagcca ctgaagcagt
     1741 gatagaaaat tatcaagaac ggatacgtga tctgtacttg gaagatttaa ccgatgatga
     1801 aaagcaagaa gtacaagaaa tacaagcact gattttgtcg atcgaacggg atggattgga
     1861 tgaaagttat cgttcgggca agctttcttc taatggttat cgtttttact cccgttttct
     1921 ttctcgattc gaacattcta tcacaagcca gattttgtct tttatcggct tttggttcat
     1981 tgttgtccgt aggttaatgc gaatcgttct ccatccgaaa atgttttggc aaagaagata
     2041 tgctgatcgt cagacattta ttagtgatga agatatccaa gaaatcagag agacatatca
     2101 aaaaaatact cagttgatta ttgaaagttt agataacttg actgatattt atgatgaaac
     2161 gatggttcaa ttttttatcc agcaacgcaa acttgaagga ataaaaatga actcggggaa
     2221 tttgatttct tcgtggatga tccagcaaga tagtctgttt acgaaaaaaa tgctaagagg
     2281 ttattatctt gaaagaaaaa tcattgatga atacgaagtt gctgaaaaaa tcacgacgtt
     2341 ttctgcgaac agctatcgca ggaatatcaa tttgttagaa tcttatacga tgaacaaacc
     2401 atctgataac ttttctttcc gatttgcgtt tcgagcaaag tcaaaaaaac gagtccaata
     2461 aaataaaaag gtaaaaattt tcaagtttta taaaaaacaa aacatatcag aacaggatcg
     2521 aatcggtcct gttctttttt tgagaacaca aaaagaacaa ataccaaaaa aattttcctg
     2581 aagttcacta tttttatgat acaatatcca agataaggag ggaacatgtt gaaagaatta
     2641 aaagtaactg acctcaaaaa aacttatggt gaaaaagatt tgtttgacca gatttctttt
     2701 ttggtccacg aaaaagaccg tatcgggttg attgggacga acgggacggg taaaacaagt
     2761 ctcttaaata ttattgccgg tatcgatagc agcgacggtg atcggcaaac agtgttttat
     2821 ccaactgatt accgtattgg ttatctttct caagcagctg aattttccga tgaattaact
     2881 gttctccaag cagtctttca aggaaacagc cccttgatcc aaactgttcg agcatatgag
     2941 gaagcattga tcgaactagg ggaaaacgga gaagaccctg atgtgcaaaa acgttatgct
     3001 aaagcagaag aacaaatgaa taaagaagat gcttggacta cagataccaa cgcaaagatt
     3061 attttgcaaa aattaggaat cagtgaatta gataaaaaaa tcagtacttt atcaggtggt
     3121 cagaaaaaac gagttagtct ggcgcaagtg ttgattgatg aacccgattt actattacta
     3181 gacgaaccaa caaaccattt agattatgaa gcgatcgagt ggttggaaaa ctatttgaaa
     3241 caataccgtg gcgcactatt gatggttacc cacgatcgtt attttctaga tagagtagca
     3301 aaccgaatct tcgaactttc atttggaaaa ttatacgagt ataaaggaaa ttatgaagct
     3361 tacgtcttag aaaaagcaga acgtgatcgt gtagaagtag aacaagaaga aaagcgcaag
     3421 cggctttata aacaggaatt agcttggatg agggctggcg tacaggcacg tggcaccaag
     3481 cagcaagcac ggatcaaccg tttcgaagat ctaaaggaga acttgtacca agtaaaccaa
     3541 gaagatgatt tagagctgaa cctagcgaca caacgtttag ggaaaaaagt actggaaatc
     3601 aaagatggca gttaccgtat aaatgaccaa acactgctag aacatttaga tttattgatt
     3661 caatctcggg aaagactagg tattactggt aaaaatggtg cgggaaaatc gacattgctt
     3721 aatattctag ctggcagaat tcccctggat agcggtacaa tgtctatcgg tgaaacggtt
     3781 catcttgcgt attatacaca agaaaatgaa gaaatggcac cagataaacg gatgattgct
     3841 tacttacaag aagctgctga agaagcaaaa acagcagatg gcagtcaaat cggagtagca
     3901 gaattacttg aacgattttt atttccaaga tttatgcatg ggacactgat aggcaaactt
     3961 tcaggcggag aaaaacgccg gttatttttg ttgaaactgc tgattcagca acctaatgtt
     4021 ttattattgg atgaaccgac caatgatttg gacatagcaa cattgacgat tttggaagat
     4081 tattttagaa gttttccagg tgctgtgatc actgtttccc atgaccgtta tttcttggac
     4141 aaggtagcag ataagttatt agtattccaa ggaaacggaa aacaagaact ttattacgga
     4201 aacatgtcca gttatttact gaagcaaaaa gagacccagc agcctgctga aaaagcgaaa
     4261 ccaaaaatac agagcaagga acctgctgaa aagaagaaat tatcttacat ggaacaaaaa
     4321 gaatgggaaa cgattgaaga tgagattgca gaacttgaag aaaaaatctc attgctccaa
     4381 gaagagatga atcatcaagg agataatttc actcgattac aagaattgca aaacgacgta
     4441 tctgaaacag aagcacaact tgaagaaaaa atggcacggt gggaatactt gagtgaatgg
     4501 gtagaagatt aggaggaaaa aggatggaac aagcgtatct tgacttagga agaaaattgt
     4561 tggaagaagg gcatcgtaaa gaagacagaa caggcacagg cacattaagc ttattcggat
     4621 accaaatgcg gtttgatctg caaaaagggt ttcctttgtt aacaacgaaa cgagtacctt
     4681 ttggattgat caaaagcgaa ttgctttggt ttttaaaagg agatacgaat atccgctatc
     4741 tattacaaaa taaaaaccat atttgggatg aatgggcatt tgaacgctac atcaaaagtc
     4801 cagactataa tggaccagat atgactgatt ttggccatag atgtttgaca gatcctgaat
     4861 tcaatgaaga atataaaaag cagagcaagc ttttttgcga gaagatccta accgatgatt
     4921 cctttgctga aacatacggc gatcttggac acatctacgg ctatcaatgg cgtcactggg
     4981 aaacaaaaga cggtggcttt atcgatcaaa tcaaacaagt gatcgaagca atcaaaaaga
     5041 ctcctgattc tagaagattg atcgtttctg catggaatcc ggaagatgtt cctagcatgg
     5101 ctttgcctcc ttgtcatacg atgtttcaat tttatgttca agagggacgg ctaagctgcc
     5161 aattgtatca acgcagtggg gatgtgtttc taggcgttcc gttcaacatt gcaagttatg
     5221 cgttgctgac tcacctaatt gcacatgaaa caggtttagc ggttggcgaa tttgttcaca
     5281 cattaggaga tgctcatctt tatatcaatc atatcgaaca aatgaaagaa caattgagcc
     5341 gagaaatacg cgcatttccg actttagttt tgaatcagga aaagcagtca gtatttgatt
     5401 ttgagatgga agatatccaa ttagaaggat atgacccaca tccggcgatc aaagctccta
     5461 tcgctgttta gaatcagaaa ggatgagaaa atgttagctg caatttgggc acaggatgaa
     5521 aacggattga ttggaaaaga agaccgtctt ccttggcgtt tgccaaatga tctgaaattc
     5581 ttcaaacaaa tgacagaagc aaatacacta gtgatgggac gaaaaacatt cgaagggatg
     5641 ggtagccgtc cgttgccgaa tcgtcagacg attgttttga cgagagattc ttcctataaa
     5701 gcagaaggcg tgcatgtcat gcatagtgtg gaagacgtgc ttgctctgga aaaagaaaca
     5761 gacggtatct ttttcatcgc tggagggtca gctgtttatc aagaatttct gccattttgt
     5821 acgatattat accgtacagt catccatcat gtattcgatg gagatgctta ttttccacct
     5881 gttgactggt ctgattggtc actgatcaat actagtcaag gagaaatgga tgaaaaaaat
     5941 cgttatccgc atcaatttga aacgtatcag cgtaatgaga atcctgtaaa aagcgggaca
     6001 ggcgaattga cgatataaaa aagctatgga tagactagct gttatttaga gctgtcccat
     6061 ccatagcttt atttttttta ttaagtaaag aataaaacag agaagtacat aaaacctgca
     6121 cctaacataa caaacaaatg ccaaacaaca tgcatatagc ggatagaatt caagctataa
     6181 aagaatgcgc ctatcgtgta agaaagcccg cctgctacca tcaaaataac accagtcatt
     6241 ccaagagagt gataaagagg aacagcagcc acgacacaga gccaccccat aaaaatatag
     6301 atgatcgtag atacttttga tactctctcc cgtttatgca acgtcaacgc tttatatata
     6361 atgccaagaa tcgcaaacaa ccagattaat acaaataaag tccaacctag ccatcctcgg
     6421 atactcagca aacaaaaagg agtataactt cctgcaatca aaagaaaaat cgaactatga
     6481 tcgaatactt ggaacacctt ttttgctttt gtaaaaatca atgaatgaaa caaagtagac
     6541 gttaaaaata aaagaatcat catcgatcca tagatagcat aagagacaat atggagggag
     6601 gaatgcaagt gggcaccttt tactaaaaga accactagtc ccgcgatact caatccagtc
     6661 ccaattccat gggtgactgc attaaacact tcatttaata tttcatacgt tcgattaaat
     6721 ttcgtttttt ccatgaaaac ggctccttta ctaggtgtaa ttaatgaaaa atcattattt
     6781 gtctgttata ctaaaaatag aaattgtctt acatgtagtt taacatgaat aaggcatctt
     6841 gttaaagaaa gagagagaga aaataatgac aaatgtaaaa atcgtaacag attcttcatg
     6901 tacgatggaa aaaaatgtac gcgatgcttt aggcattcgt gtcatgccgc tatccatcat
     6961 gatcgacgga acagtatatc ccgatgatga ccaactagac ggcgaaagat ttatggaaat
     7021 gatggcgaaa gcaaaaaatc tgcccaaaac aagccaacca ccaattggag aattcatctc
     7081 gatgtatgat gagctaggag aagacggcag tgaagtgatt tcgatccata tgacaaaagg
     7141 cttgagtgga acagtagaag cagcaagaca agccagtaat ctaacaaaaa cgaaagtaac
     7201 ggttatcgac agtgatacca ctgaccaagg attatctttt caggtaattc gagcagctga
     7261 attagcaaaa gaaggtaaaa cagtagagaa aatccttgaa gaagtcaaaa aagtacaaga
     7321 caatacaaaa ttatacatcg gaatatccac actagataac ttggtaaaag gtggaagaat
     7381 cagccgaaca actggtttgc tgtctagtgt tttgaacata cgcgtggtga tgaatttcgc
     7441 ccattctgaa ttaatccctg taactaaggg gcgaggaaag aaaacgttcg ataaatggtt
     7501 taataatttg aaaaatgaac tgaaagaatt gccaaatgtg cgacaaatcg gtatttcaca
     7561 tgcggatgca aaagaattgg cgcaagaatt caaagagggt ttgcaagaat tattcccgga
     7621 catgcatatc cctgtactgc atacgaatcc ggttatcgct acgcatactg gtaaagacgc
     7681 gtttgcaatc atgtattatg tagattagtc gaaaagagga taagccctca gcctgaaagg
     7741 cttgcagctt attctctttt tctttataaa attaggaaaa taattgtttt cttttttcat
     7801 aaagactacc tttttgataa aatttttgat aacattagaa ccaatcgaat acaagaggtg
     7861 aaaaaatgaa attaacgaaa cgacatttga tcctcgtttt gttcccatta ttaattgcga
     7921 tcatcatcta tgcaggttta gctgcttcta taccgaaagc tggcccacta atgaaaccag
     7981 taactactgt gagagaagat ccaaataaaa aagaaaaact tcactacata gctatcggag
     8041 attcgctgac tgaaggagta ggagatcaaa ccaagcaagg aggattcgtt ccccttgtcg
     8101 caaatgatct aaaagaccgt tataatttga ccgcggttga aacagaaaac tatggtgtaa
     8161 atggtgaacg aagtgaccag atcttaaagc gagtaaaaac aaaagaagaa attcgaaaca
     8221 atatcaaaac agctgatttt atcacactga ctgttggcgg taatgatttg atgaaagtta
     8281 tccaaaataa tttattcggg ttaacggtca attcctttaa aaagccactg aaaaactatc
     8341 aggaaaatgt cacagaacta ttggaagaat ttcgatccct caataaaacc gcacctattt
     8401 acattttagg catctacaat ccattttatt tgaactttcc tgagatcact gacatgcaga
     8461 caattgttaa caattggaac aaaggaacag aaacggtgac aaaaaaaatg ccgaactgct
     8521 actttatccc aatcaatgat ttgctttatc aaggattgaa tcaggaagta ggtgtcacag
     8581 aagaaggaac agatcaaaca actagcacga cagaaaatct aaatggcatc aaaaataatg
     8641 tgctctatga agaagatcat ttccatccaa ataatttagg ttatcaattg atggcaaatg
     8701 cagtgagaga tcagctgatc gagacacaaa accaatggtt agagaaggag gatgatcaat
     8761 aaacatgaaa acaagatctg acgtatcttc aaacaaaaca aagaaaacaa attactggaa
     8821 attcgccttc cttatccttc ttggggtagt acttggttcg accgtatttt taggcagccg
     8881 tatttttgct aatcgggaac cagaactccc agaaatacca gctcttacgg aaagacaagg
     8941 agatcctgtc ttaacgatca attcaaataa agaaaaagtc aatcaaatca tcagcttttt
     9001 ccttagtgag tatcaaaaag atagtgatat tgaatataaa ttttatttgg aaaatgaagc
     9061 actactcaat ggtactttcg aagtactagg ttttcctatc gatttctatt tatattttga
     9121 tccgtatgtg atggaaaacg gaaatgtcca actaaaagct agaagtcttt ctatcggaac
     9181 attgagtttg ccaatcaaag atgtgatgaa tatgatcaag agaaactata aattaccaga
     9241 ttggatcgaa gtcaatacag atgatctgac tatcatgctt aggttggatc aattccgaat
     9301 gcaaaacggg atgtatatta aagcagataa aatcgactta gtaaatgatg acattcggtt
     9361 tagtctatat ttgccaaaag atacctctga tgcttcaaac aactcaaata ccaacaaaac
     9421 tagcaccagc agtactgaaa gcaagacaaa agaaaataaa aaatcatcgg atgagtagta
     9481 ttagaggggg aatcataatg gaacgagcaa tatttgcagg aggctgcttc tggtgtatga
     9541 tccagccttt cgacacgctt cctggtatcc atacagtgat gtcaggatat actggagggc
     9601 atgtaccaga tccgacttat gaacaagtaa aaagccaaac gactggacat acagaagcag
     9661 tggagattat ctatgatcca acattgattt catatgaaca attagtagaa ctttactggc
     9721 agcaaactga tccaactgac gctttcggac aattcgagga tcgcggtgac aattatcgcc
     9781 cggtgatctt ttatttgaca gaagaacagc ggatcattgc tgaaaaaagt aagaaacagt
     9841 tagctgaaag tggacgtttc gaacagccaa tcgttacaaa aatcgaacca gcccaaccat
     9901 tttatctagc agaagaagac catcaagagt attataaaaa gcatcctgaa aattttaaaa
     9961 gaaaccatgc acgccgggct gcctttatcg aagaaaattg gaggaacgaa gggtgaatcg
    10021 aagctttttt cattatttaa tgacactgcg aggcggtggc acacatgatg ctttatctgt
    10081 tttcgctaca gaagccggta aagacatcca atttcctaag cacagctcta gctacgaaga
    10141 aatttctaat tatctggaac tgaatgtcga ctatttgccg tccatggata tctttgacga
    10201 agcatgggaa aaatatttag aaaataatca tgacatataa gagatagttt tgtactttat
    10261 gatcaaaaaa gttttttgtc caatagccta attgaaagaa ttatttttat ttcagctatc
    10321 tagtcgcatt tttttgatat ttttcttata ataaagaaag aatgaaaaaa agagggatgg
    10381 attgatagag attgacaaaa aaacaacgct atattaatcg cttctggctt gtattcaaat
    10441 acttacttgt ttctgtattc cttgcgttca tgttgcgggg atttttattc atcccggtac
    10501 cagtggaagg caattcaatg gaaaacgtgt tgaagcaagg tgatatggtt gtgatggaaa
    10561 aattttcgga gatcagacga tttgatattg ttgtttttca attagcagat ggcacgattt
    10621 atatcaaacg agtaatcggt cttccaggag aaaatgtcag ctaccaaaat gatcaattga
    10681 agatcaatgg gaaagtagtt aaggaacctt atctaactaa aaacctgaaa tcagatcatg
    10741 caaatgcatc ctatacgacg gactttacac tacaagagct aacgggacaa tccaagcttc
    10801 cggaagataa ttattttgta cttggagata atcgaagagt ttcaaaagat agtcgttcgt
    10861 ttggcacgat caataaaact gatattctag gtaaagcaag atttgtctat tatccacttg
    10921 atgaaataaa atggatccag tgagaaacaa taaagcgtgc agtctgttga gactgcacgc
    10981 tttattgttt aatccaaaat cagtttacta ccttagtacg taaaatcaaa cagctcgttt
    11041 aaacactttt ctagcctcta aagttttgat aaatgaataa acaaccatta tttgaatagg
    11101 gatttggatc atattcctga tgaatctacc tagaaaaatt actttgaaat ctgcaccaaa
    11161 caaaacagac atcagccaag aattgataaa aaggctgact gggatcataa tcaataattg
    11221 ggcagcgatg acggaaggca ggtttatctt tttatgatat aaaaataagc cattaataaa
    11281 tccaccaagg aaagccgtga taagaaaagc agcttgaaac gttcctgaac caaatatcgt
    11341 gaaatttaaa gtgttcgaca acatttcaag caaaccagcc cagatcggtc catatagata
    11401 acccataagc gccatactta aaaatccgaa tgtgatttga aaataagcag gaccaatcgc
    11461 tatcttgtat aagatgacat caagggctaa taaaagagca gaggtcgaca acaatcttgc
    11521 attcatttcg ggcaatctaa aaacgtcttt tgcaatcaaa gtgttcaaaa tattctctcc
    11581 tttgtcagtt aataataaaa ggataccata aaatcaccaa tgtgtcatga cacattggtg
    11641 atttacatac actggcatct aacaattaaa aaaagggtga gaagactgct tttataaact
    11701 gtaaaaaaga gattgtacga ataaaaaaaa tagaggcgga gaatacttat cgtatcatcc
    11761 gcctttgttt ttttgttata aaaaacgtca gattagttat ctgcttacat cttcatccat
    11821 acgggttcta atgtatttcc gtctagatct tggacttcta atgaaaacat ttcttcttca
    11881 ggcattccca tatctacttc gtggaaagta ccaccatttt cttttgcaat ttgagcaaat
    11941 ttttttactt catccgcgtt ttcaacacta aacgaaatca aagcaccact tgttttttta
    12001 ttatcagcta tttctttatc ttttataaat tttttataaa aatcatgaga gagaagcatt
    12061 atccaaaaag tgtcatccca taccattgaa ccagcttctt cagtagaaaa ttcttcattt
    12121 tttttaaaac ccagcttttc ataaaaagca acggaacgat tgacatcagc aacaggaaaa
    12181 ttaacaaaaa ccatactatt catttgtttc gtctcctttc tgttttgttc gtctatcatc
    12241 tcttatttag gaaacgctgt caaaaattta gattcatata tagaaaccaa aataaaaatt
    12301 tgcatcatca aaaaagtgaa gatgtgatag aatgaggact ggttcacttt cacttaacta
    12361 atagatggaa tttctttata ataaaaaagt gaatttatat tgaaaaagaa aaaaacaagt
    12421 aaagccgggg aatattccgg tatgaaagga atggagagaa caatgaccat ccaatggttt
    12481 ccgggacata tggcaaaagc ccgacgagaa gtttctgaaa aaatgaaata tgtggacatc
    12541 gtatttgaat tggtagacgc acgattacct ttatcttctc gtaatccaat gctagatcag
    12601 atcattcagc aaaaacctcg ccttgtttta ttgaataaag cggatctggc agatccacaa
    12661 cagacaaagc tgtggcaaga atattttcgt aaacaaggcc atcttgcatt agctatcacg
    12721 gcacaagaaa gtaaaggaat taaaggtcta gtacctgcgg ctaaagaagc attgaaagaa
    12781 aaacgggcaa gagatgctgc tcgggggatc aagcctcgcg ctattcgggc aatggtctta
    12841 ggtattccaa atgttgggaa atctacgttg atgaatcgac tagtaggcaa gaaaattgca
    12901 cagacaggaa ataagcctgg cgtaacaaaa ggtcagcagt ggcttcgttt aggtaatgag
    12961 ttggaattgt tagacacacc agggatttta tggcccaaat ttgaagatga agaaatcggc
    13021 aaaaaactag cgctgacagg cgcgatcaaa gaccagcttg tccatttaga tgatttagcg
    13081 atttacggat tagacttttt tgcccgatat tattcaggaa gaatcagcga tcgttatggt
    13141 ttatcaatcg agcaagaaga aaaattggca ccggaattac tgatggatat tacagcaaaa
    13201 cgtgggtata aagaagacta tgatcgtggc agcgaattag tcgtgcatga tattcgtcaa
    13261 ggaaaacttg gacgatacac actggatcgt tgcgaagaaa tggagcaaaa aagtgatgac
    13321 tgaatccatc caaagtatca aagaacgatt gaaaagcata cagagaatag atgatcctac
    13381 actagaatca ttaagaaatg atccacgcaa aggcgtgcag caagcactgg cttcttttga
    13441 acgacgattg aaaaaggaag cattaattaa ggaaaaatat gaagaaatgt tttgctttga
    13501 aaagcaaggg tacgcacaag gtcaccaatg gattgccggc attgatgaag taggaagagg
    13561 accattagct ggacctgtcg tggcagctgc agttatcttg ccgaaaaatg agatcatatt
    13621 agggctgaat gactccaaac aattatcaga gaaaaagcga gaacttcttt atcaacaagt
    13681 tcaagaaaaa gccctggcaa tcgggatcgg gatcgttgat cagcagacaa tcgatgatgt
    13741 gaatatttat gaagcaagta aattagcgat gatccaagca gtagaaaaat tgtccattgt
    13801 accaagctat ttgttgatcg atgcgatgac cttggatttg cctattcagc aggaaaaaat
    13861 aatcaaaggg gatgcacgat ctgtgtcgat tgctgctgca agtatcattg ctaaagtata
    13921 tcgagaccaa ttgatgaaag aatatgacgt gctttatcct ggatatggtt tctcgcataa
    13981 tgcaggttat ggaacaaagg aacacttaga aggacttgaa cgacaaggaa ttacgccaat
    14041 ccatcgtaaa agttttgcac ctgtaaaaaa atatttacaa taaaaaacag ccgcttttac
    14101 gtatcttatt agaaagagag acgaaaggcg gttttatgat gtatcaaata gaagaaaatt
    14161 tattgaaact tgcttataca aaaggaatca gtagtcaagg aaaatgggca cttgctaact
    14221 ggatgatgca gtatccttat aaagaaatcg gatttgaaga catcattaag ataggtaaaa
    14281 taaccaaaca tcgggagctg tttcgcaaaa gttggcagga aattcacgct aactggggca
    14341 aaatccaatc gaaacagtcg tttatcactt gctttgatcc caaatatccc cctcagctgc
    14401 ttcacttgac ctatccgcca attgtactgt tttataatgg tgatctatct ttactttctt
    14461 gtaacatgtt aagcgttgtt ggtggaagac acacttctgc tttagccaaa aaaacagttt
    14521 attatttact aaaaccagtg atagaagctg gatatgtgat cgtcagtggc tgcgcgaaag
    14581 ggatagatac atacggtcac caagcagcaa tctctcatgg tggacggaca atcgcagtca
    14641 ttggaacagg gatagagcaa gtctatcctg ctgaaaatcg tgacttgcaa gaggtgattg
    14701 caaatgatca tcttcttttg agtgaatatc ctcctcaatc cggcccgaaa aagcattgtt
    14761 ttccaatgag aaatcggatt atcgcagctt tgtctaaagg aacatgtgtc tttgaagcca
    14821 agaaaaaaag cggctctctg ataacagcac agcaagcatt ggatcttgga agaacagttt
    14881 tttctgttcc aggaaatatt ttaacagaac attctaccgg atgtcatcat ttgatccaag
    14941 acggtgcagt ttgcacggtt tcgggtgaag atatcttggc agaatttaaa gaataacacc
    15001 atacttttca tttgcttttc ttgacaaacg ttttctgaat ggatatgatt agctacgatt
    15061 tgtatgaatc ctcttttaat agtaggaaca cgacaatgga aaggagtcca ttcagtaatg
    15121 gcgtataaat atttagtgat tgtagaatca cctgcaaaag ccaagacaat tgagaaatat
    15181 cttggacgaa actataaagt aatggccagt gttggccata taagagattt accgaaaagt
    15241 aaaatgggta tcgattttga aaacaattat gaaccccatt atatttctat acgcggaaaa
    15301 ggcgatgtca tcaaaagcct gaaagccgca gcaaaaaaag ctcaaaaagt ttacttggca
    15361 agtgacccgg atagagaagg agaagcgatt gcttggcatt tagcgtacct acttgggttg
    15421 gatctgaaag aaaaaaatcg ggtggtcttc aatgaaatca caaaagacgc agtcaaagca
    15481 gcttttaagg aaccaagaac gatcgatgta gatttagtag atgcacagca agctcgtcgt
    15541 accttagaca gaatcgttgg ttattcgatc agtcctattc tctggcgtaa ggtcaagaaa
    15601 gggttaagtg caggacgtgt ccaatctgtc gctttaaaaa ttattattga ccgtgaaaaa
    15661 gagatccgag aatttgttcc agaagaatat tggagcatcg acggtaattt taaaaaagct
    15721 cgcaagaaat tcaaagcaaa tttctgggga atcgacggta agaaaaagaa attaccagat
    15781 gcacaaagtg taaaagaagt cactgctaga attgatggaa cagacttcga agttaaaaaa
    15841 gtagaaaaga aagagcgcaa aagaaaccct gcgaatcctt tcactacaag tagcctgcaa
    15901 caagaagctg cccgtaagtt aaactttcga acaagaaaaa ccatgatggt agcacagcaa
    15961 ttatatgaag gaatcacttt gggtaaacaa ggaacagtcg gcttgattac atacatgcgt
    16021 actgattcta cccggattgc cgatacagca aaagcagagg ccgcagcatt tattgaagat
    16081 acgtatggaa aagaattttc tagacatgat caccgaaaga tcaaaaatgc tcaaggcgca
    16141 caagatgccc atgaagctgt gcgtccaacg agtgtgcttc gtacaccaga tgaactcaaa
    16201 caatatttag ataaagatca attgaaactt tatacattga tctggtcacg ttttgtggct
    16261 agtcagatga caccagctat tttagataca atgaaagtga cattagaaca aaatggtgtc
    16321 atcttcattg cgaacggttc aaaaatcaaa ttcaaaggat tcatgcaagt gtatgtggaa
    16381 ggtagagatg acggcaaaga agagaaagaa aatattcttc cagaacttga agaaggcgat
    16441 gtagtccaat ctgttgatat tgaaccaaaa caacatttta ctcaaccacc agcacgtttt
    16501 agtgaggcta cgttgattcg tgcactagaa gaaaacgggg tagggcgacc ttccacttat
    16561 gcaccaacac ttgatacgat ccaaagacgc tactatgtaa aattgacaca aaaaagattt
    16621 gagccgactg aactaggaga aattgtcaat tcattaatct gtgaattctt ccctcaaatc
    16681 gtcgatatcc atttcacagc agaaatggaa ggagatttgg ataaaattga agaaggcacg
    16741 gaagcgtggg tcaaagtggt tgatcgtttc tataaaccgt ttgaaaaaga actgacgaat
    16801 gcggaagaaa aaatcgaaaa aattcaaatc aaagatgaac cagcaggatt cgattgtgat
    16861 gtctgtggac atccgatggt gataaaatta gggaaatatg ggaagtttta tgcttgcagt
    16921 aattttcctg attgtcggaa tacgaaacca atcgtaaaag aaatcggtgt gacttgccca
    16981 gtatgtcatg aaggacaagt cattgaacga aaatctaaga aaaacagact attctatggt
    17041 tgttcccgtt tcccagaatg tgaattcact tcttgggata aaccagtggg cagaaattgt
    17101 ccaaaatgtg acggatatct ggtcgagaag aaagtcaaag gcggtaaaca agtagtctgt
    17161 gtaaatggag attacgaaga agacatccaa aaataataga aaagaggttc tttcattgaa
    17221 aatggtaaat gttgttggag cagggcttgc cggaagtgaa gctgcttggc agatcgcaca
    17281 agcaggagtc cctgtccgtt tatatgaaat gcgtccagtc aaatcgactg aggcgcatca
    17341 cacaagtaat tttgctgaac tagtatgttc caattcatta agaggaaaca gtttggctaa
    17401 tgcagtaggg ttattgaaag aagaaatgcg ccgattgaat tcggtagtaa tcacttcggc
    17461 agatgaaaca gcagtgccag ctggtggtgc cttagctgtt gaccgcgatt ctttttctga
    17521 aacaattacc cgaaaagtca aagagcatcc attagtaaca gtgataaacg aagaaattac
    17581 tgaaataccg gaaggaatca ccgtagtagc aacaggacct ttgacttctc atccattagc
    17641 agaaagcatc aaagcattca atggttcaga tggtttttat ttctatgatg cagctgcacc
    17701 aatcgtagac aaagctacga tcgatatgga taaagtatat ttgaagtccc gctatgacaa
    17761 aggagaagca gcttacttga actgtccgat gacagaagag gaattcaaag ctttccatga
    17821 ggcactaatc aatgccgaag tggcagaact taaatctttt gagaaagaaa aatattttga
    17881 aggatgtatg ccaattgaag taatggcaca gcgaggattc aaaacgatgc ttttcggacc
    17941 tatgaaacca gttggattgg aagatcctaa aactggcaaa cgtccttatg ctgttatcca
    18001 gctgcgtcaa gacaatgctg cagcttcttt atacaacatc gtgggctttc agactcactt
    18061 gaaatggggc gagcaaaaac gtgttttccg gatgattcct gggttagaaa atgctgaatt
    18121 cgttcgctat ggtgtgatgc accgaaacag ctttatgaat tcgccagaat tgctgaaacc
    18181 gacttaccaa tcaacgaaac gcgaagatct gttctttgca ggtcagatga ctggtgtaga
    18241 aggctatgtt gaaagtgcag cgagcggact acttgctgga atcaacgccg cacgcttagc
    18301 aaaagaaatg gaaccagtcg agtttccaca agaaacagct attggaagta tggcttacta
    18361 cattactcat gcggaaggaa aacatttcca accgatgaat gccaactatg gtctgtttcc
    18421 tgaactgcca gagcgcattc gagacaaaaa agcaagatat gaagcaattg cacaacgagc
    18481 tttaaaagct aatgaggcaa taaaaacaga attagaaaaa actgcaatcc caaatgagta
    18541 aggaaactcc atgaagaggg tgagacggat agtctcgct
//
LOCUS       DAFTHM010000050        18522 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFTHM010000050 DAFTHM010000000
VERSION     DAFTHM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.050"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..577)
                     /locus_tag="L7C88_001673"
     CDS             complement(<1..577)
                     /locus_tag="L7C88_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBP9558494.1"
                     /translation="MNHKLSETEQYLWNFIEHLILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGEKTNKNIKNKIYVFIFQFFK"
     gene            719..1651
                     /gene="pfkB"
                     /locus_tag="L7C88_001674"
     CDS             719..1651
                     /gene="pfkB"
                     /locus_tag="L7C88_001674"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBP9558495.1"
                     /translation="MSIYTCTMNLAIDLFIETDEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAGDYLCVSGSLPRGLSPKVLIEISRICLIIDS
                     SDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENVLLSLGE
                     KGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLAGYMNRRSLDETLRKSIAAGSS
                     TAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            1633..3096
                     /locus_tag="L7C88_001675"
     CDS             1633..3096
                     /locus_tag="L7C88_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBP9558496.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFVGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSSDPDHAQYNATAAMVKAVDDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLIILPKQLDGLKAIVLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEYSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLTQGN
                     TTFMAGASAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKRDNKATNRTVIEEGRAGGLS"
     gene            3093..3551
                     /locus_tag="L7C88_001676"
     CDS             3093..3551
                     /locus_tag="L7C88_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBP9558497.1"
                     /translation="MTIIHEENIFLQQPLDNQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLKKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKIEIATILTKEIGEDI"
     gene            3548..4522
                     /gene="lacD"
                     /locus_tag="L7C88_001677"
     CDS             3548..4522
                     /gene="lacD"
                     /locus_tag="L7C88_001677"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBP9558498.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDEPVEINVQKQIVIERIGSECEAEGIPFF
                     LELLSYDATIGDPSSLDYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QDTCYSQAEASAYFYEQSKVTEQPFIFLSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATSIYVNK"
     gene            4963..5691
                     /locus_tag="L7C88_001678"
     CDS             4963..5691
                     /locus_tag="L7C88_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBP9558499.1"
                     /translation="MESSNKGKSLYYQLVDLLKDRIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELENQGYIYRRHGKGTYVSDLSDKSSNLAGAYSFTEEMREIGRVPKTV
                     ILEFRQMEANKRIAKNLNIHLGETVFKLKRLRLADEEPLMVERSYLPAKLFMGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDAVVLRIADGAPVLHLTRITYNVKN
                     EIIEYTDSVARADQFHYKIRHIRK"
     gene            5709..6905
                     /locus_tag="L7C88_001679"
     CDS             5709..6905
                     /locus_tag="L7C88_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBP9558500.1"
                     /translation="MFELSKNKLKQIGAAITTQEIKQQPDLWKETIDRLMQSQENLAL
                     FFDQIKKEANGRRIRVIFTGAGTSQYIGDTLLPYLNEHGDNQFFIFHSFGTTDIVASP
                     KEFLFPNEPTLLVSFARSGNSPESVAAVQIANEQVETLFHLTITCAKEGMLAKNAQDD
                     KQNYLLLMPERANDAGFAMTGSFTCMLLSALWIFDQTAMEKKERYLEQLVKIGQDLLS
                     RDQEIQKLLPDFFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVVGFVSNQPYTRNYDLDILEEIKEDRVTANVIAIAQPGTIDFSGMTVLLE
                     DSVSKLPDAYLALAMIMTAQIIALYTSIKVANKPDTPSPTGTVNRVVKGVIIHKYETE
                     GEMTDE"
     gene            6898..7893
                     /gene="lacD"
                     /locus_tag="L7C88_001680"
     CDS             6898..7893
                     /gene="lacD"
                     /locus_tag="L7C88_001680"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBP9558501.1"
                     /translation="MNEEKNRAMERLSTKDGIISALAIDQRGALKKMIKSLGKEPSED
                     QISEFKELVSAELTPYASAILLDPEYGLPAAKVRAKETGLLLAYEKTGYDATTPGRLP
                     DLLADWSSLRLKEQQADAVKFLLYYDVDEAPEINHLKHVFIERLGSECEGENRPFYLE
                     LVSYDAQISDSSSPEYAKVKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVNGYSTG
                     EFIHSKEEAAAFFKEQSEATPLPFIFLSGGVSTELFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGKDGAIHWLRTNGRENIETLNKVINETATPWFNKTKSKKVKMK"
     gene            7890..8831
                     /locus_tag="L7C88_001681"
     CDS             7890..8831
                     /locus_tag="L7C88_001681"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HBP9558502.1"
                     /translation="MITTVTLNPSIDIAYTIEELNLDKVNRVETVNKTAGGKGVNVAR
                     VLNLLGEEVIATGLIGGQHGEYLKNQLDQLGIMHQFVPIKGETRDSIAILHSSRQTEL
                     LERGPFITKKEQQTFTDHFEQLLEISDIMTISGSLPQGCPLDYYKQLVALADKKGKDI
                     LLDTSGKFLLEVLEGKEKPLLIKPNLEELGELIGQRICSSIQLEKIQSLLAHPIFEGV
                     PWVVVSLGERGAVAKVAQCFYEVIIPKISVVNPVGSGDATLAGSAHALSKRQSIEEIL
                     AFSMACGMANAQQEKTGWIDPMKVTMLMKHIQVKKIK"
     gene            9007..9486
                     /locus_tag="L7C88_001682"
                     /pseudo
     CDS             9007..9486
                     /locus_tag="L7C88_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632653.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
     gene            9499..10389
                     /locus_tag="L7C88_001683"
     CDS             9499..10389
                     /locus_tag="L7C88_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9558503.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLNAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDRHVEDMNYQAIERNFLMGALPWSLSRMIPVFLAL
                     AFGGGLVENVVSVLNGNLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHLSYLILGFT
                     ITALLATLFSNVQLLGTSVASVVKDLPATFNSLPMLAVALIGLALAMISYKNDQNKDH
                     QPLASEPSHSVEGEIEDDEI"
     gene            10376..11185
                     /locus_tag="L7C88_001684"
     CDS             10376..11185
                     /locus_tag="L7C88_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBP9558504.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDNTPELKEMMKTHTQFFNTSNFFNTIITGIDLAMEEKEGIASKETVSGLKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPIGVFIWIFAQIVVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKILPAGIVGGVYWLLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            11199..11600
                     /locus_tag="L7C88_001685"
     CDS             11199..11600
                     /locus_tag="L7C88_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBP9558505.1"
                     /translation="MSRQLVLISHGKFCEELKKSTEMIMGPQEDIYTLPLLPEDGTET
                     YKQKFLTVTDSLNDFVVLCDLLGGTPANIISKLIMEGQQITLYAGMNLPMVIEFINSQ
                     MIGSEPEFVRAGCESIVSVNELINGIAEEEE"
     gene            complement(11646..12596)
                     /gene="yidC"
                     /locus_tag="L7C88_001686"
     CDS             complement(11646..12596)
                     /gene="yidC"
                     /locus_tag="L7C88_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBP9558506.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(13156..13431)
                     /locus_tag="L7C88_001687"
     CDS             complement(13156..13431)
                     /locus_tag="L7C88_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBP9558507.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            13539..14303
                     /locus_tag="L7C88_001688"
     CDS             13539..14303
                     /locus_tag="L7C88_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBP9558508.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            14426..14929
                     /locus_tag="L7C88_001689"
     CDS             14426..14929
                     /locus_tag="L7C88_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBP9558509.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            15338..15979
                     /locus_tag="L7C88_001690"
     CDS             15338..15979
                     /locus_tag="L7C88_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBP9558510.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKK"
     gene            16149..17417
                     /locus_tag="L7C88_001691"
     CDS             16149..17417
                     /locus_tag="L7C88_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBP9558511.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAAYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(17444..18496)
                     /locus_tag="L7C88_001692"
     CDS             complement(17444..18496)
                     /locus_tag="L7C88_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBP9558512.1"
                     /translation="MLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLIS
                     FGIYLFVLLYETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSL
                     ANLLTLILAIFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLY
                     QFNRPRYNQDFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGG
                     QGADEKVPEAMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAI
                     FSSNNYHIFRAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICG
                     LLFAGSAFLSLITLLF"
BASE COUNT         5895 a         3082 c         4036 g         5509 t
ORIGIN      
        1 atttaaaaaa ttgaaaaata aagacataaa tcttattttt gatgttttta tttgttttct
       61 caccgttcaa agaaacaaaa ataacgctgt ctttcttagt tagtttccga ctgatgcttt
      121 tgataatttc tggatcagta tgcatctgac aattttttcc cgttaattga agttttacca
      181 gcatttcttg gccaatcatt tctgaaaatc ctcgggcaaa gacaaaaacc cggtcagcaa
      241 atttgattct ttgtattgca tcttcaatgt tcccgatttc caacatattg attgtacgta
      301 ccacttcttg ttcatttttt agaatggctc ggcggattcc tttgtctact ttatctaaaa
      361 atgaaaaatt gatgttcttg ttttctcctt cttttagatg atgcttaaac gaagtaaacc
      421 cttcatagcc tttctttttc attgtccgca caatggtggc tgttgagaca tttgcttgtt
      481 cacttagttt cacgatggaa tagttaggga tctctaggat gaggtgttcg ataaagttcc
      541 agaggtactg ctctgtttca cttaatttgt gattcatatt ctttccttct ttcaccaaaa
      601 gttagttaaa aaaagcacga cgagtttata aatgtaaagg ttttctttgt gttgggacga
      661 ttaagaaaac attttctatt tcgcgtattt cataatagaa tcaaggaggt cgttggttat
      721 gtctatctac acatgcacga tgaatttggc aattgatcta tttattgaaa cagatgagat
      781 gcatcctttt atggtaaacc gcacaaaaga ggatgacatt caggcaaacg gaaaaggggt
      841 gaatgtgtca ctagtattaa agatgctaga tttcccaagt acggcattag gtttttctgc
      901 tgggttcaca ggaaagtata tagaagacta tttacagcag aaacaaatcc aaacagagtt
      961 tattgaagtg cctggtatga cgcgtatcaa tgtatttaca caagtcaatc aaacgggaga
     1021 agaatacaaa ttagtgaatc aaggacctga aataccgcag acagctgttc ataatttttt
     1081 aaatcaaata agagcattac aagcagggga ttatctttgt gtttctggga gtttaccaag
     1141 agggctgtct ccaaaggttt taatagaaat cagtcggatt tgtttgatta ttgatagtag
     1201 tgatcaagaa gtcatggatt gtttacccta tcgaccgttt ttgctgaaac caaatgagga
     1261 agaactttct tcttggttcg gacgaaaaat ggttacagat gaagattact ttgtttatgg
     1321 acaacgacta gtagagtcag gcgcagaaaa tgttttgtta tccctcggtg agaaaggagc
     1381 gattcttttt acgaaagaca gggtgattcg aggaaactcg ccaaaaggaa aagttgtcaa
     1441 tacagcatgt gcaggtgatg ccatgttagg cactttttta gcaggataca tgaatcgacg
     1501 atcgcttgat gaaacgttac gtaaaagcat agcagcaggc agctctactg cttttcgtaa
     1561 aggactgact gattttttgg atgtggagga attaagtaaa caaatcaaaa tcaaggaaga
     1621 gaggttcgaa agatgggaaa atatcaacta attgcagcaa ccggttgtcc gacaggaatt
     1681 gcgcacacct acatggcgca agaggcatta gagcaagcag ctaggaaaaa aggcatcacg
     1741 atcaaagtgg agacccatgg acaaattggg atcgagaatg aattaacggc tgaagaaatc
     1801 aaacaggcag atgctgtcat tattgccgca gacaaagatg tccattcaga aagatttgtg
     1861 ggaaaacgag tcattgatgt ttctgtcagt acaggaatca aggatgcaca acggctgatt
     1921 gacgaagcat tggcaggaaa aggtactgtc ttagcagata atgaagctgc tgatacttta
     1981 gaaccagaag cgataagtgg tgctaatttt ggtcgtagca tctataaaaa tttgatgaac
     2041 ggtgtctctc atatgttgcc tttcgtggta gctggcggag tattgattgc tatttcattt
     2101 gccgtttggg gaatctattc ttctgatcca gatcatgcac aatacaatgc tacagcggca
     2161 atggtaaaag cagttgacga tgcagcaatg ggaatgatgg ttccagtttt agcagcttat
     2221 attgcagaag ggatcgcgaa acgtccaggg ttagtcgttg gatttgttgg tggaatcgta
     2281 gccatgaatg gcggtactgg atttttagga ggtattttag ctgggttctt agcaggttat
     2341 tttatcttat ttttgcaaaa gctactgata attttaccta aacaactaga tggcttgaag
     2401 gcaatcgtct tatatccagt tattggtgta gcatttattg gcatcgtgat gtctttgctg
     2461 gcaggtccaa tgaaggctat aaatgaagga atgatgagct ttttagctgg atttgaatat
     2521 tcgaatccac ttgttcttgg cgtgattgtt ggctgtatgt gtgcgtttga tatgggagga
     2581 ccggttaata aggcggcata tgtaacagga acagctcttt tgacacaagg aaacacgact
     2641 tttatggctg gtgcgtcagc agcttgcatt gcaccaccgt tgattactgg ttttgctact
     2701 ttattgtttg gtaaatattt tgatactaat gatcgtaatg caggtttggt taattttatt
     2761 ttaggatcaa ctcatattac ggaaggagct attccgtttg ctgcgaaaga cccgatccga
     2821 gtattaccaa cgatgatgtt aggctcatca attgctgctg tcttgaccta tctgtttggt
     2881 gtccaagtac cagccccaca tggcggtttt ttagtgttac ctgtagtgac gggaaaaatc
     2941 caatgggtta cagcgattct tattggttcg atcgttggtg gagtgatact aggtttgatc
     3001 caaaagaaaa gagtaactga taaagacaag aagagggata ataaagcaac aaatcgtaca
     3061 gttatcgaag aaggaagagc aggaggttta tcatgacaat cattcatgaa gagaacattt
     3121 ttttacaaca gccattagat aatcaagaag aagcatttaa gtttttagca aagcaaacat
     3181 tctgtttagg aatcgctcat gacgaaaaag aagtatatca aaaacttctg gaaagagaaa
     3241 aagaaggtac tacaggaata atgtcaggtt ttgctatccc tcatgcgaag tctcaaacaa
     3301 tcaatgaacc tagtttgatt atcgtcacac tgaaaaaagg aattgaatgg aacagtttag
     3361 atagacagtc agttgatttt atttttgcgt tatttatccc agattcagaa gcaggaacga
     3421 ctcatttgaa attattgtct ctcgttgcac gatcattgat gcgaaaagag gttacagaac
     3481 agttgagagc tgcaaaatca aaaatagaaa tagctacaat attaactaaa gaaataggtg
     3541 aagatatatg aagaaaatga gtatagaaaa acaggaacgt ttgaagcgat tgacggatga
     3601 agctggaatt attagcgcgc tagctatcga ccaacgtggt gctttgaaga aaatgatcaa
     3661 ccaatataaa gaagctacat cagaagatat catccaattt aaacagatgg tttctcagta
     3721 cctgactccg tatgcttccg ctattttact cgatccagaa tatggtctgc ctgcagcagc
     3781 gcttcgagag aaagaatgtg gtttgttgct agcttatgaa aaaaccggct atgatgcgaa
     3841 aatgccaggc cgactaccag atttactgaa tagttggtca gtgaaaaggt taaaagaagt
     3901 gggtgcggat gcttgtaaat ttttattgta ctatgacgtt gatgaaccag tagagattaa
     3961 tgtgcaaaaa caaatagtta tagaacggat tggttcagaa tgcgaagcag aaggcatacc
     4021 tttcttttta gagctccttt cttacgatgc aactattggc gatccgtctt ctcttgacta
     4081 tgcaaaagta aaaccgcata aagtgattga agccatgcga gaattttcaa aagaacgtta
     4141 tcaagtggat gtattgaaag tagaagtacc agtgaatatg agatttgtgg aaggatatgg
     4201 gcaagatact tgttatagtc aagcagaggc atccgcgtat ttctatgaac aatcgaaagt
     4261 gactgaacaa ccgtttattt ttttaagtgc gggagtcagc gctgcactat ttcaagatac
     4321 attgcgtttt gcaaaacaat caggttcgac attcaatggt gtcttatgtg ggcgagcaac
     4381 atgggcgaag ggagtagcac cttttgttac cgaaggcgaa gaaaaagcga gtagttggat
     4441 gttagaagaa ggaaaacaaa atattaaaga attaagtaca ctattagaag aaacagcaac
     4501 ttctatttat gttaacaagt aagagaaagg attgtctgag tgacagattc aaaaaataat
     4561 tagttattta aaaaaatgtt tgtcaaattt tatagaaaaa aagtataaaa ctgcaaaagt
     4621 tatctaaaac taataataac atttgtcatt aataagctat ttttagttgt tgtaaatgat
     4681 attggaagta ataaaacgat agttgtagga atatcatagg gattaatgtg gatcacgctg
     4741 ctcgataagt tagaccattt tgacggatcg cttatgtggt tcgtcttttt ttctgttctt
     4801 ttattggtaa ctggtatttt tgaggtatct ttgtctattc aagatataaa gctttaaaga
     4861 gctgttataa tagctttttt ggtctaaaaa acctttgaca aatgattaat aattcactat
     4921 tcttgtgttg tggttataac cagtaaagaa gaggtgattt ttatggagag ctcaaataaa
     4981 ggaaaatcat tgtattatca actagttgat ttattgaagg atcgtatcga aacacagatg
     5041 actccgcatg ataagctgtt atctgaaaga gaactttgtc aacactatgg ggtgagtcgt
     5101 accaccgtac gtctggcttt acaggaattg gaaaatcaag gttatattta ccgaagacat
     5161 ggaaaaggta cctatgtctc tgatttgtct gataagtcat cgaacttagc tggagcatat
     5221 agctttacag aagaaatgcg cgaaataggg cgcgtcccta agacggtcat tttagaattt
     5281 agacaaatgg aagctaataa gagaattgct aagaatttga acatccattt aggtgaaact
     5341 gtatttaaac ttaaaagatt gcgtttggca gatgaagagc cattgatggt tgagcgttct
     5401 tatctaccgg cgaaactatt tatgggactt gatttgccgt tacttgaaag taaaccgttg
     5461 tatgatgtgt tttcacagga ttatgaacaa caagttcaat tagctgatga agagttttat
     5521 gcaagtatcg tgcaaaaaaa agatgctgtt gtgctacgaa tcgctgatgg cgctcccgtc
     5581 ttacatctga cgaggataac ctataacgtg aaaaatgaga ttatcgaata tacagatagt
     5641 gtagcaagag cggaccagtt tcattataaa attcggcata tccgaaaatg attgagaggg
     5701 agaacaacat gtttgagcta tcgaagaaca aattaaaaca aataggtgca gcaatcacga
     5761 cacaagaaat aaaacaacaa ccagatctct ggaaagaaac aatcgataga ttgatgcaaa
     5821 gccaagaaaa tttagctcta ttttttgatc aaataaaaaa agaagcaaac ggaagaagaa
     5881 tacgtgttat ttttacgggt gcaggaacgt ctcaatatat tggggatacg ctcttaccct
     5941 atctaaatga acatggagac aatcagtttt ttatcttcca cagttttggc acgacagata
     6001 ttgtagcttc accaaaagaa tttttgtttc caaatgaacc gactttatta gtttcatttg
     6061 ctcgcagtgg caacagtcca gaaagtgtag cggctgtgca aattgcaaat gaacaagttg
     6121 aaacattgtt tcatttgacg attacttgtg ctaaagaggg gatgttggca aaaaacgcac
     6181 aggatgataa acagaattat ctgttattga tgccagagag agcaaacgat gcaggttttg
     6241 ctatgacagg aagttttacg tgtatgttat tgagtgcttt atggatcttt gatcaaacag
     6301 caatggagaa aaaagaaaga tatcttgaac aattagttaa aatcggtcaa gatcttcttt
     6361 caagagatca agaaattcaa aagttattac ctgatttttt tgaacggatc gcttatctgg
     6421 gttcaggaag tttggcaggt gcgacaagag aagcacaatt aaaaatttta gaattaacag
     6481 caggtaaagt tgctacaatt tttgattctt cgatggggtt tcgtcatgga ccaaagtctt
     6541 ttttaaatag cgagacactc gttgtaggtt ttgtgagcaa tcaaccatat acgcgaaatt
     6601 atgacttaga tattttagag gaaataaaag aagatcgggt cactgccaat gtcattgcga
     6661 ttgcgcaacc gggtactatt gatttctcag gtatgactgt gctattggaa gactcggtga
     6721 gtaaattgcc cgatgcctat cttgcattag cgatgattat gactgcacaa atcattgcac
     6781 tctatacttc aatcaaagta gctaataaac cagatacacc atctccaaca ggcacggtca
     6841 atcgagtagt caagggcgtc attattcata agtatgaaac cgaaggagaa atgacagatg
     6901 aatgaagaaa aaaatagggc aatggagaga ctatcaacaa aagatgggat tattagtgca
     6961 ttagcgatcg atcagcgtgg tgctctaaaa aaaatgatca aatcgttggg aaaagagcca
     7021 agtgaagacc aaatcagtga attcaaagaa ctagtatcag ctgagctgac accctatgct
     7081 tctgctattt tattggatcc ggaatatgga ttgccagcag caaaagtcag agcaaaagag
     7141 acggggttat tgttagctta tgagaaaacc ggctatgacg caactacgcc tggtcgtcta
     7201 cctgatttat tagcggattg gtcttctctc agattgaaag aacagcaagc ggatgcagta
     7261 aaattcttac tttactacga tgttgatgaa gcacccgaaa tcaatcattt gaagcatgtg
     7321 ttcatcgaac gtttaggtag tgagtgcgaa ggagaaaatc gtcccttcta tttggagtta
     7381 gtttcttatg atgcacaaat aagcgatagt tcttctccag agtatgcgaa agtcaagccc
     7441 cacaaagtta ttgagatgat gaaagaattt tctgatccaa aatataaagt tgatgtgttg
     7501 aaagtagaag taccagtcaa tatgaattat gtgaatggct attccacagg tgaatttatt
     7561 cacagcaaag aagaggctgc tgccttcttt aaggagcaaa gtgaagcgac tccattacca
     7621 ttcatttttt tgagtggggg tgtttcaaca gaattatttc aacaaacact gatttttgct
     7681 catgaatcgg gttccacctt caatggtgta ttgtgtggac gtgcgacatg gaaagatggg
     7741 gtcaaagcat acgtcgaaaa tggaaaagac ggagctattc attggttaag aacaaatggg
     7801 agagaaaaca tcgagacttt aaataaagta ataaatgaaa ccgctacccc ttggttcaat
     7861 aaaacaaaaa gcaaaaaggt gaagatgaaa tgattacgac agttaccttg aatccttcca
     7921 tcgatatcgc gtatacaatt gaagaattaa acctcgacaa agtcaatcga gttgaaacag
     7981 tcaataaaac agcgggagga aaaggagtga atgtggcgag ggttctaaat ttattaggag
     8041 aagaggtgat agctactggt ttaataggtg gccagcacgg tgaatatcta aagaaccagc
     8101 tagatcagtt agggatcatg catcagtttg ttccaattaa aggagagaca agggattcta
     8161 ttgctatcct gcatagttcg agacaaacag agcttttgga acgaggcccc ttcataacaa
     8221 agaaagaaca acagacattt accgatcatt tcgagcagct cctcgaaata tcagatatta
     8281 tgacgatctc aggtagttta ccccaaggat gccctcttga ttactataag caattggttg
     8341 ctttagctga taaaaaaggg aaagacatat tactagatac ttctggtaaa tttttgcttg
     8401 aagtattgga aggtaaggag aagccactac ttatcaagcc caatctggaa gaattaggag
     8461 aactgattgg ccaacgtatc tgttcttcga ttcaattaga aaaaattcag tccttattag
     8521 ctcatccaat atttgaagga gtgccatggg ttgttgtttc tttaggagag agaggtgctg
     8581 tggcaaaagt tgctcagtgt ttttacgaag tcattattcc taaaatatca gttgttaatc
     8641 ctgttggttc aggtgacgcg acccttgcag gatcggccca tgcgttatca aaaaggcaat
     8701 caatcgaaga gattctcgca ttttctatgg cttgtggtat ggcaaacgcg caacaagaga
     8761 aaactggctg gatcgaccct atgaaagtta cgatgttgat gaaacacatt caagttaaga
     8821 aaatcaaatg aacttaaata taaaagaaag cgttttcttt agttgggaag gaatttgttc
     8881 ttagcttaaa aatgaaatat aagaaagaaa aaatgaaaac gttatctttg aaacagaagg
     8941 gatatttgat gatgtcacag ttttaattga acaataaata gaaaaaatag ataaggagaa
     9001 tgcatgatgg caattattgg tgtaagaatc gatggacgtt tgatacatgg ataagtagca
     9061 aatctttgga caacgaaact gaatattagt cgaatcatgg tcgtggatga tgaggtagcc
     9121 acaaacacaa ttgaaaaaag tggattgaag ttagcgactc cagcaggggt aaaattaagc
     9181 attttgccaa tcgaaaaagc agcaacaaat attttagctg gcaaatatga ctctcaacga
     9241 gtattgatcg tagcaaaaaa gccagatcga atcttatctt tagtagaaaa aggagttcct
     9301 atcaaagaag taaatgtggg gaatatgtca caaacgaatg aaacacggtc cattacaaaa
     9361 tcaatcaatg tggtagatgc agatatcgaa gtatttaaaa aattagatca gcttggtata
     9421 catttaattg ctcaaatggt accaaacgat aaagcagaag actttatgaa tcttttaatc
     9481 aaataggagg aatgatccat ggatattcaa tggtggcaga tcttattatt aacattatat
     9541 gcaggttatc aaattttaga tgaattacag atctattctt caatgagtgc gccagtgttt
     9601 gcagggttat atgcaggttt agtaatgggt gatttaaacg caggtttgat tattggtggc
     9661 agtatgcagt tgacagtttt aggagtgggg acgtttggag gcgcatcaaa aatagatgcc
     9721 aactctggga cgattttagc aactgccttc tcgatttctc ttggaatgaa tccagaacaa
     9781 gcgattgctg ctattgcagt gcctgtagca agcttaatga tccaattgga tattttagct
     9841 agattcgcta acacatactt tgcccatcgt attgaccgtc acgtagaaga catgaattat
     9901 caagcaatcg aacgcaattt cttaatggga gctttacctt ggtcgctctc tcgtatgatt
     9961 cctgtatttt tagctttagc atttggtggt ggattagttg aaaatgttgt ttctgtttta
    10021 aacgggaatc taaaatggct aggcgatgga ctttcagtag caggagctgt tttaccagct
    10081 gttgggtttg ccattcttct gcgctattta ccagtaaaaa aacatctatc ttatcttatt
    10141 ttaggattta cgatcacggc attattagca acgttattct ctaatgttca attattagga
    10201 acaagtgtgg caagcgttgt taaagatctt ccggcaactt tcaattcgct gccgatgctt
    10261 gctgtagcat tgattggtct agcactagca atgatcagtt ataagaatga tcaaaacaaa
    10321 gaccatcaac cattagctag tgagccatca cattctgttg agggggaaat cgaagatgac
    10381 gaaatctaat tacaaattaa caaaagaaga ttttaagcaa atcaatcgaa gaagtttgtt
    10441 cacttttcaa ttaggttgga actatgagag aatgcagggt tctggctatt tatatactat
    10501 cttgccacaa ctaagaaaaa tatatggaga caatacacca gaattaaaag agatgatgaa
    10561 aacacatacg caatttttta atacttctaa tttttttaat acaatcatta ctgggattga
    10621 tcttgcaatg gaagaaaaag agggaattgc ttcaaaggaa accgtatcgg ggctgaaagc
    10681 tggattgatg ggttcctttg cagcgattgg agattccgta tttgctgctt tgattccaac
    10741 gatttttggg gctttggcgg cgaatatggc aactgatgga aatccgatag gtgtgtttat
    10801 atggattttt gctcagatcg ttgtcatggt ttttcgttgg aagcaacttg aatttgcata
    10861 caaagaagga atttccttag ttactactat gcaatctcgc ttaactgcat taacggacgc
    10921 agccacttta ttaggggtat tcatggtagg ggcattagtt gcgacaatga tcaatgttaa
    10981 attttcatgg gcaccaacga ttggcgatgt gacattgaat atgcaaaact atatcgatat
    11041 gatcttacct aaaattttac ctgctgggat cgtcggtggt gtttattggt tattaggaaa
    11101 gaaaaacatg actcctactc gagcgatttt tatcgtatta attgtgtgtg ttgctttatc
    11161 tgcattgggt gtgatttcga aataagggag agcgaaaaat gagtagacaa ttggtattga
    11221 ttagtcacgg aaaattttgt gaggaattga aaaaaagtac agaaatgatc atggggcctc
    11281 aagaggatat ctacacgtta cctttattac cagaagatgg cactgaaaca tacaaacaaa
    11341 agtttctcac tgtcacagat tcgttaaatg attttgtggt actatgcgat cttttaggtg
    11401 gtacacctgc aaatatcatt tctaaactaa taatggaagg acaacagatt actctttatg
    11461 ctgggatgaa tcttccgatg gtcattgaat ttatcaactc acaaatgatt ggttcagagc
    11521 ccgagtttgt tcgtgcagga tgtgaaagca ttgtctctgt caacgaatta attaatggaa
    11581 tagcagaaga ggaagagtaa caaaaaagat gagggcttag ctctcatctt ttttgtccta
    11641 tgtttttatt tccgcttctg ctgctttcct gcgttgcggc ctttgttgtt tgtactgttt
    11701 tttggttgtt tgatttgttt tgttgcttgt ttgttgttag ctggctttgc tgattctgtc
    11761 acgtcttttc ttggagtgac gacttgtttt ggcgggtttt gtttcaactc ttctgccact
    11821 tgtgctttca aacgtggttt catcataacg tttgtgatga atgtttgcag acagctgaac
    11881 acaccaccga ctacccagta aagtgtaaca ccggctggcg cactgatcga catgaagacg
    11941 atcatagcag gagagacgat tagcatcgta cgcatcgtct ttttctgttc ttcaggaata
    12001 ccgatcgttg agatgtatcc ttgaagcaga taggcgaccc ctgcaatgac aacaagtacc
    12061 atacttggtg agcctaaatc gatgccgtag aaagatgatt cccgaatacc ttctgtataa
    12121 cgtgccgtaa agtacaaggc agagaagatc ggcatttgga tcaatagagg cagacagccg
    12181 attccgccgg tcatactcaa tccgttttcg cggtatactt gctgcatttc tgcttgtgct
    12241 gccatttgtt cttcacgtgt tgttgcagct ttcaattttt gttgggctgc ttcaacttgt
    12301 ggttttaacg cttgcatttt ttcagattgg atcattgttt ttttcgattg actaatacct
    12361 agtggcaaga tgatgatacg gacgatcaca gtcattgcaa taactgccca gccataagac
    12421 caattgaaat tctcaactag atatgtaatc gcttggccca taggatggac gagtactcga
    12481 taaacgattc ccgaagtgtc agggtttccg tttgaatcca tccgcacaca gccagataaa
    12541 aagagcagga tactgacaag tccggatccc aataaccagt ttttccattt attcatagaa
    12601 tacttcctct tctataattt ttacacaaac ttaactatac taaaaaagcg catggaattc
    12661 aatcaacttc atagaaattt catataaata ttcgttcttt tacgtagcga aaaattttga
    12721 aaaaaagaca aaaaatcaag aaagaaatac ttggaaagaa aagagtgatt ccaagtgttt
    12781 ctttcttatt taaaaaacta aaaacttttt tgttctgtct ggaaaatatg ggttaagcaa
    12841 atttattgca agttatagat cagctttttt actacctatc tttaatactt gaggcaaagc
    12901 gtctcaaaaa caaccttatc gacggtgttc aaaagtcagt ttctcggtat taagtcaaat
    12961 tttatgcaaa aatgtggaaa gccattttca caaaattctc cttactactc aaaactaagc
    13021 gactttctca caaccttatt gacggtgttc aaaagcttgc atctacggca ttaagtccag
    13081 cctgttgaaa aatatggaga gctatttttc acaacctgtc cttaatgctt gatgcagacc
    13141 agctttttca caaccttatc ccaccacatc aaatttcttt cgttcctcaa tcatcgggtc
    13201 ttcttggaca tccacatact gcactcgtcc acttgggctc ggagatttct tgacttcttc
    13261 aataaatttc tggatgatgt cgtcattgcc gattgcttcg atcgtgactg agccgtcatc
    13321 ttcgtttttt accgttccag tcacgcctag ttgatcagcg accatcttgg tcatgtagcg
    13381 aaatcctacg ccttggacgc gtccttggac gttcatttta actttgcgca tgttcgtcac
    13441 ctttctttcc tattttataa attaatgata ccgatttttt taggatgaaa caagctcaag
    13501 cacctattcc atgatataat catggggagg tgaggaatgt gaaagagatc caatcagcaa
    13561 aaaatccaag aatcaaagaa ttaaaaaaac tacataaaaa gaaatatcgg gaagaaaagg
    13621 aagaatatct tttggaaggg ttccatctga ttgaagaagc tgcgtcgtct gatgcagaaa
    13681 taaaagaact ttttgtgaca cagcgaggca tgaaagaatg gggagactgg ctggccgcaa
    13741 acaaagagat ttctactttt ctagtttcgg atgaggtcat ggatgctgta tcggatctac
    13801 ctacaccaca aggaatctta gcagtgatgg cgttaacggc tgaaggcacg ccagattttt
    13861 caggaggatg gctgttatta gataatgtac aagatcctgg aaatgtaggg acgatgatcc
    13921 gtacggcaga tgcatttgat atggctggtg ttttattagg caaaggaacg gcagatattt
    13981 atagtacaaa ggtgctgcgc agcatgcagg gaagcaatta tcatttgcct gtgttgcaaa
    14041 aagatttgac agaagtgatt cctttaatga aagacaaagg gtttacagtg tatggcacag
    14101 aattaaatga agaagcacac gccttagaca aagtagaaaa atcagataac ttcgcaataa
    14161 tcatggggaa cgaaggtcag ggggtaagtc aggaaatctt gtctttgact gatcagaacg
    14221 tatatatccc gatgaaagga aatgcggaat cgttgaatgt tggggttgcg gcagggattg
    14281 ttctttatca tttttcttta tgattaagga actattaagc tttggctatt ttatccaagg
    14341 cgactagaat aatccgaaca ctggtggtat acttagatca atttcagaag aaaatgaaat
    14401 tcaaaaaggt ggcagatcga taattatgac agaaaaatgg cgtgaagacg aagaatatat
    14461 gtcttatgta gaagatcttt tagaaacaga agcagtgaaa aaattagcga attacacaca
    14521 gcatgttcat tccactcgtt tggagcattc catcagtgtt tcttactata gttatctgct
    14581 cgcaaaaaaa tggggtggca atgctaaagc aacagcgcgt gctggacttt tgcatgatct
    14641 gttctactat gattggcgta cgacgaaatt tgatgaaggc acacatgcgt atatccatcc
    14701 aagaatcgct gtaaagaatg cagaaaagat caccgatttg tcggatcttg agcgagatat
    14761 cattttgaag cacatgtggg gcgcaacgat tgcaccgcct aagtacaaag aaggatatat
    14821 cgtaacattc gtagacaaat actgcgcagt caaagaagcc gctcagccta tgtcagcaag
    14881 tatgcgtaag agatggcaac gttacttcgg aaaagaatcc tcgatttaac aggtaaaacc
    14941 aataatagac catattgagg ttgtgacaga agtgggtcag cttcaagaaa taagaaggaa
    15001 tttacgaaaa ttgcttctca aatttttgtg aaattccggc ttattttttg aagaagctac
    15061 ttctggaaca ccgtttgttt gtagaaaggg actttgacac gacttttgtc acagtccttt
    15121 ttctgtttgc agttgactat ctgctcaaga tacggtttac ttttatttat cgaatgaatc
    15181 atgtacatag aagaatgaac attaaagggg gtgatgataa gatgcaaaac gtatcttatt
    15241 taaaagagtc cgggatcttc aggtaacaca tactttgcag aagatcactt ttttctacaa
    15301 agtatgcact ttggttagaa gaaaggactt taaaatcatg gaacaaacaa tgaaaccata
    15361 tcaatatttt tttataaaaa gagaagtaga gcagttatta aatgcgtact catctgtcaa
    15421 tgactcaaaa acggtacaaa cggttcaggc tctagcagct gaaaagattc gcgatgtatt
    15481 aggttacgaa ccatcagaaa tcgatacgtt tttaacgaca gttttagatg taaaactgac
    15541 aaaaacgcaa gcagaacgag cattggagga gctgaagcaa atcgtccagc cgtttatgca
    15601 gccgagcaaa ccacaaatcg agaaattatt ccgaaaagtg aaaaaactca aacaacccgc
    15661 ttggaatgaa atcgacttgc aagcacatac gtacatcggt tggaatgatc cagggacgca
    15721 aaaaaaattc atggtttatt acgaagatgg aaaattaaaa gggatcagcg gtactttatc
    15781 accaacgatt aataagggaa tctgtgcgat ctgtcagaaa acatcgaatg tctcgctctt
    15841 tctttctaca acgaaagccg gttctgatgg cacgtatacg aaaaagggga attatatttg
    15901 tcatgatagt gatcaatgta atcaacagtt aacgaaattg gctcctttct atgaatttgc
    15961 tgaacgtgta aagaaataac gataatttta ttgtttttta cagaaaaata tgctatcttt
    16021 taatggaagt gaataggtga tggtgttcgc ctttaaatgc taacgtaaga tagctaatga
    16081 cgcctactaa agtctggggc cagccccttt ctttagtagg cgttttttta tttgaggagg
    16141 aattttttat ggaaaaacaa ttaccgagtc cagtgcgtat tttgatgtac atgttgaagt
    16201 ggctggtggt cacagcgatt ctcggagtat tcatggggag cttgtctgct tttttcttaa
    16261 atagcctgac gttcgtgaca gatatccgac tagcacatcc ttggctactt tatctattgc
    16321 cagtcagcgg cgcgcttttt gcttatcttt atgcgtatca tggcggtctt tctagtcgtg
    16381 ggaataactt agtgatcgat caagggaatg gaggagaaga gaagatccct ttgcggctca
    16441 ttccattgac cttgtttggg accatcacta cccatttatt tgggggatct gttggtcgtg
    16501 aaggaacagc agttcaaatg gggggagcat tagctgataa tatagcgcat ttattccgat
    16561 tggataaagc agaacgggag attttggtta tcagtggaat cagtgcgggt tttagttctg
    16621 tatttggcac acctttagct ggaacattat ttggattaga agtgttggca atcggtaaag
    16681 tccgaacaga agcaatattt cctagcttct ttgctgcgct ttttgcaaat ttcatgacag
    16741 aaagctatgg tgtttctcat ctacattacc aaatgggtgt gattcctgaa tggagtatgt
    16801 tgctgttctt caaagttttt gttgctggga ttgcttttgg tttgattggt tgggtattca
    16861 gccgttcgat cgtcttttta aaagcgcggt atgcgcaatg gattcctcat cctgtttggc
    16921 gaaatacgat aggtggagca gtagttgtag ccgcagcgtt gattttgcaa acacaacgtt
    16981 accttgggtt gagtcttccg ttactgcagg aatcatttaa tggacaggca catgcttatg
    17041 attttattgg gaaattattc ttcacggtct tgtctttagg tgcggggtac caagggggag
    17101 aagtgacacc actatttgag attggtgcaa cgcttggcgc agtactagcg cctttgctcc
    17161 atgtttctgt tccttttctt gctggattag gttttatcgg ggtattttct ggtgcgacaa
    17221 atacaccgat tgcctgtttt gtgatgggaa tcgaattatt tggttcacaa gctgctgctt
    17281 acttctttat gatctgcttg atcagcttta tgtgttcagg aaacagcggt atttattctg
    17341 cacagcaagt agccgtcaaa aaaggaatac tattcttgcc aatcgtcaag agaataaaag
    17401 aaaaaaacaa ggtgtgacat atgttttgtc acaccttgtt tttttagaaa agtaaagtga
    17461 tcagtgataa gaatgcggaa cctgcgaaaa gcaatccgca aatgatcata tgtctttttt
    17521 tgttcatcat caagatggcg atgtattctc ttaaaaacgc gttaggcaag taatagaaag
    17581 ctgtttttgc cccaatgcca tttgccttca gtttcgcttg tcgtgcatag agaccagctc
    17641 tgaaaatgtg gtaattgttg gaactgaaga tcgcgcgata gggacctttc atttgctgat
    17701 ccatgatttc ctttgaatag cgcatattct ccaaagtggt tgtcgaattg gtttcgacaa
    17761 gaatatctct ttcaggaatt ccttgttcca tggcatattg tttcatcgcc attgcttctg
    17821 gtactttttc gtctgctccc tgtccacccg acattaatag gataggcgga tttaatgtcg
    17881 cacggctttg tgcccaataa aaagcaatcg ccttattgat tcgcttggca agaagaggag
    17941 aaactgtttc tccattgatc aacccggcgc ctaacacaac gatgaagtct tggttgtatc
    18001 gagggcggtt gaactgatac aagaatgaga cagtcaaaaa gttgtagaat acgataaata
    18061 gatagatcaa gatcaatggg atgcagaaaa acaaagcatt tatccattgt ggtaaatatt
    18121 ttaacaagaa aaagtcaaaa acaagaaaca atgtaagaaa aatggctagt atcaacgtta
    18181 aaagattagc taatgaatgc gactctctac gtaaaactgt gacaccgttc caaaaaagaa
    18241 aaacgatcaa tccataaatg ccgaatagaa agacaagcag taacgggatc gtgatcaagg
    18301 caatcagtcc gccaagaaaa atattttgtg tttcgtatag caagacaaac aagtagatac
    18361 caaaactaat gaggaaaata ttgaataaaa gaccattcaa cagccttcgc ttttctgaaa
    18421 aataggaaaa ggcaaagata ctgaaaaaca ctaagggaat caaaaaataa aaggtcgaat
    18481 aaaaaatttc caacacgaca aaataagtca agattaccgc aa
//
LOCUS       DAFTHM010000051        17791 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFTHM010000051 DAFTHM010000000
VERSION     DAFTHM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.051"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            202..1077
                     /locus_tag="L7C88_001693"
     CDS             202..1077
                     /locus_tag="L7C88_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558513.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(1222..1374)
                     /locus_tag="L7C88_001694"
                     /pseudo
     CDS             complement(1222..1374)
                     /locus_tag="L7C88_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(1642..2973)
                     /locus_tag="L7C88_001695"
     CDS             complement(1642..2973)
                     /locus_tag="L7C88_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9558514.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIAILIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(3122..3835)
                     /locus_tag="L7C88_001696"
     CDS             complement(3122..3835)
                     /locus_tag="L7C88_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBP9558515.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            4010..5434
                     /locus_tag="L7C88_001697"
     CDS             4010..5434
                     /locus_tag="L7C88_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBP9558516.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            5733..6440
                     /locus_tag="L7C88_001698"
     CDS             5733..6440
                     /locus_tag="L7C88_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBP9558517.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            6427..6750
                     /locus_tag="L7C88_001699"
     CDS             6427..6750
                     /locus_tag="L7C88_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBP9558518.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(6839..7876)
                     /locus_tag="L7C88_001700"
     CDS             complement(6839..7876)
                     /locus_tag="L7C88_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBP9558519.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(8197..9180)
                     /locus_tag="L7C88_001701"
     CDS             complement(8197..9180)
                     /locus_tag="L7C88_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBP9558520.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(9595..10365)
                     /locus_tag="L7C88_001702"
     CDS             complement(9595..10365)
                     /locus_tag="L7C88_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9558521.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(10358..11293)
                     /locus_tag="L7C88_001703"
     CDS             complement(10358..11293)
                     /locus_tag="L7C88_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558522.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(11609..13258)
                     /locus_tag="L7C88_001704"
     CDS             complement(11609..13258)
                     /locus_tag="L7C88_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBP9558523.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(13375..15978)
                     /locus_tag="L7C88_001705"
     CDS             complement(13375..15978)
                     /locus_tag="L7C88_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBP9558524.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(15990..17039)
                     /locus_tag="L7C88_001706"
     CDS             complement(15990..17039)
                     /locus_tag="L7C88_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBP9558525.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(17065..17379)
                     /locus_tag="L7C88_001707"
     CDS             complement(17065..17379)
                     /locus_tag="L7C88_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBP9558526.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(17395..>17791)
                     /locus_tag="L7C88_001708"
     CDS             complement(17395..>17791)
                     /locus_tag="L7C88_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBP9558527.1"
                     /translation="SDKKSVVEKLSKLLETNGFVSDHKQFQKDVFDRENHMTTGIGKN
                     IAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLLAIKDTDKGTNHLRILAE
                     LSGRLMDDEFVKRIKDSRNKKELVKALSF"
BASE COUNT         5449 a         3607 c         2953 g         5782 t
ORIGIN      
        1 ataaataaaa aacaaaaaaa gttccatctt taaaacacgc tattctttta ctttttctca
       61 cattctctaa gaaaagaaaa ggagaatgaa tttttgacaa ttcgagcaaa agtgattatc
      121 aaatatgtaa aatcagctac ttttttctta aacgtttctt tatactaaat ataaataagt
      181 gtttcatgaa aggagaacta gatgaataat tggcttgagt attttcctga aaacgttttg
      241 gaacgcggtt acagctatca tctgcacggt tttgtccgtc atttgaacta tacaagcaag
      301 tacttgtccg caacagtttc tggcacggaa gattataagg tagtgatcac ttgggatgaa
      361 aagaccaaca tgacttgtga ttgtctatat gccatagaag gaaaaaaatg caaacacatg
      421 gctgctgtct tattcgctta cgaagaacgt ccaataaaaa aatccaacta ctcactttcc
      481 gaactctcgt cccttgtttc ctccgctagt tcctctcttg tacgggagct tttaacagag
      541 attcttatag aacatccgca atttatcgaa cgcttcaaag ttaagatgcc atttcatgca
      601 ataaattatt cagataaatt aacaactatc atccataaat acgatcatat tatcaagaaa
      661 aacaaaaaca ggaaaacagc gaagttcatc atggagatgc gaaagttcat ccaagaagca
      721 gttgaatcgc tcattcagca aaatgcctat cttcccgcat tcgaattgat caatgaagtg
      781 attgctactc tcgaaacatt ctattgggag cctgaggatg aacgaaccct tcttctgata
      841 gaggactgtt attatttatg gaaagaatta ttagcagaag cacctcatgc agaaaaaagg
      901 caaatgttct cttggttcgt ctgccaagtc gatcatactg acgcctctta ttcaaaacgc
      961 tactccataa aaatcctgaa agaagacttt cgggaaaaag aattttctaa ccaaaagaaa
     1021 aaaatagata aaaaaactaa agaaacggta aagaaagacg atttcaatga aaaatagcaa
     1081 gtaaacgata acaaccatcc taaatccaca agaaatacag cagaccttgc tttaaaaaca
     1141 cgaatcatgc aaaggatgaa gtaaagaaga cttaacgcgt acccaatatt agtcatttga
     1201 ctattaggta cgcgttttgt tttataagtc atgacaaatt tccttcgttg ctgggtagat
     1261 tttccggcat tgttgataga ttttatgata cttttctaca ttttgtaaga gaggttccac
     1321 tgcatctgta tattggataa aattctgaca acaactttca ggtgtgtcga accactctaa
     1381 tctttaaaga taaatattaa aataacgatt aataatatta acagtcttta tttttcacca
     1441 ccaaaaacct atctttgcat atactaaata gacgtatata cacagatagg tttgtcttgt
     1501 gaaaaataat gattatcctt accaaaaaat gtttgttttt ctacatgttc gtacttatca
     1561 aaaaatatga tccttattga aattactggc tatttatatt ccaacgactt cttgtgttaa
     1621 tttttgttat ctcatagtaa attatgtttc attttcactt aatttagttg tcacgtgttc
     1681 gtcaattcgt aaaaacggta aatatataaa cacacttgcg gctataatta atatttgtaa
     1741 aacagctgct cgccagtctc cggctgttgc taaaaatccc gatataactg gtggcgtagt
     1801 ccaaggaatt tgcactacta catgattaat taatcccaca gcagttgcaa aatatgctac
     1861 tgtcaaagaa aaaatcggtg caagcacaaa gggaataatc agactgatat taaatacaat
     1921 aggcaatcca aaaataatag gttcgcttat attgaatata gcgggagtta ccgataattt
     1981 agcaaagtcc ttataatctt ttctacgact gaagataaat attgcaatca atatagcaat
     2041 cgtatttccc gatccaccca ttaccgcaaa ggtatcttta aaggccatat tgataatatg
     2101 tggaatttgc tctttgtttg cataagctgc catattttct tgcatattct gaatcaaaaa
     2161 cggatctaac aatgaacctg atattactgc ttgatggata ccaaatccaa aaaatagatt
     2221 agcaatagat gtaattaaca aaaatcctgg taaaccagtt gtaattttac ttaatggctc
     2281 tgtaactatc gtggtaatta gcttatttat atccatatta aacaattgaa tgattataaa
     2341 tgacaataaa gcaaacgagg taatcgtaat aatgattggg attaatacat taaaagactt
     2401 taaaacagcg ggaggaatat ttccggatag ctgaatctgt agtttcttat tattagaaag
     2461 tttaataaat aattctgtag ccgctaatcc aacaaatata cctacaaaca ttcctgaagc
     2521 tcctgtatag gatataggta tcacacccgt cacttcaaca gctttatccg cattttcagg
     2581 agtaaacatc atctgcatag gtgttaatac aacaaatgtc gaaatagcaa ctaataccgc
     2641 tgcaatatga tttgtataat ttctgcttgc acacatatga taagatactg ctgctacaac
     2701 taataatgta gttatgctta atgtaccatt ggcaattgaa gtaccaattt gttgtaacgt
     2761 ggtcaatgta ctagtatcga caatttcccc catgaatcct gttggttcta agatcactga
     2821 attaataagt gtcacaaatc ctgctaacat cataaatggc ataaatgtag caaacgcatc
     2881 tcgcaaagtt cttaaatgga tctgattccc caacttagtc gcaactatac caaatttttc
     2941 aaatacaatg tccttcctgc tacttttgcc catatttttt ctcctttatg cttattgtaa
     3001 tcgattactt tttccaccca aataatacat cacttatcaa aaaaagtaaa tacttttaat
     3061 taaatatata tatctttttt agtataaaaa aataagctct gaaaaaataa ttttcccgag
     3121 cttatttttc aacaaaaaca gcttcaaaaa caaagtcttg atataaatgt ctcgataccg
     3181 aatactcgaa aggtttacca gacgatagag caacaacttt gtctatctca atcataaatt
     3241 cacctggatc tatttttaat atttttgcgt caaattcatt cgcagtatct cctttgatac
     3301 gtatgtgcga agtctttatt tccagaccca gttcatttgt gatataagca tatacagatt
     3361 tctttaaatg ttttggttcc aagcctggta tgactgctaa tggcatgaat gtttgctcaa
     3421 tcgagtatgg ttgacaatca ataaaacggc ttcgtacaat attatataca tagtctttta
     3481 cactgatact taatttatca gctacttttt tcgatggaag ttcaattgag aaagtatgga
     3541 tttctgaatc tacgtgttct tcaccaacca cgctaaacaa accttcgttt ggaccaagaa
     3601 ctcgtgagtt atcaattggt gttctgacga cttcagtccc atacccactt ctacttcgca
     3661 aaactccttc ggaaacaagt aagtctacgc ctttctttac tgttaacttg cttgtatgat
     3721 aaataactgc caattcatct cctgtaggaa gtttctcacc aattttatac tctccattta
     3781 caattttttt ctttatatct aagtaaattt ccatatactt cgcaattttt ttcaatggtg
     3841 accctccaat caaaaacata tcttcatcta tactttaaca taaataaacc gataaaatcc
     3901 acatcaaaat tatacacaca ataaaaaaga tatatatatt taaacaaaac tatttacttt
     3961 aagttgtaag cggtgttatc attaagtgga aacaggaggt aaaaaaatta tgacaactat
     4021 gaaaaagcta acttttccag atgatttttg gtggggttcc gcttggtcag ctgagcaagc
     4081 agaaggaaaa ggagaaacag gaaaagcaga gactatctgg gatcgctggt ttaaagaaca
     4141 accttaccgg ttttatcaac gaatcgattc ctctattaca accgatcaca tccatcaata
     4201 taaagaagat atagaactaa tgaaaaaaac tgggcataac tcctttcgcg tttctatttc
     4261 ttgggcacga atgtttccaa atggcggtac cggaaaagta aatcccaaag ccatttcttt
     4321 ctatcgaaaa ttattttccg aaatgaataa taacggaatc aaagtatttg ccaacttata
     4381 tcattttgac atgcctgcta ctcttcaaga taaaggagga tgggaatcac gtgaagtagt
     4441 tgatgcttat gttcattacg ctgaaacttg ttttaaagaa tttggtgact tagtttgtca
     4501 ttggtttacc ttcaatgaac cacttgggcc tattttaggt acttatcttg aagattttca
     4561 ttatccaaac ctcattgact ttaaacgcgg agcgcaagca gcattcttca ctatacttgc
     4621 acacgcaaaa gcaatacaag tatttaaaga actagctctt cctagtaaaa taggcgttat
     4681 tctaaatttg agtcctactt ttcctcgtag tcaaaatcct gctgatgtga aagcagcaga
     4741 aatcgctgat ttattttata cgcggagctt tttagatcct atggttaaag ggaatttttc
     4801 taaaaagctt atcctgttat tacaagaata taatcagctt cctgaagatt atacgaaaga
     4861 agatcttgta tgtatctacg aaaataccgc tcaaattctt ggactaaact attacgagcc
     4921 acgtcgcgtc aaatctcgtt cttctatggt ggatacatct agtccatttt taccagagtg
     4981 gtttttcgaa ccacatatca tgcctggacg acgaatgaac gaataccggg gatgggaaat
     5041 ttacgaaaaa ggaatttatg atttgtgcat ggatatcaag aaccattatg gaaacatcga
     5101 agcatttatc tcggagaacg gaatgggcgt tgcggatgaa gaacgtttca tggatgatac
     5161 agggcaaata attgatgatt atcggattga gtatatcaaa gatcatcttg cttacttatg
     5221 gaaggcaata aatgaaggat gtaacattaa ggggtatcat ctttggacat ttattgattg
     5281 ctggtcatgg atcaacgcct ataaaaaccg atatgggctg gtttcactcg accttactac
     5341 tcaaaaaaga acaattaaaa aaagtggcga attttacaag caattaagtg atacaaatgg
     5401 atttagatac gatgtagact tgttagttga ataatattct aaaattccac ttgaagtgaa
     5461 cacattagaa aacaagaata atgagaaata ccaataacaa atactttttc ttcatacttc
     5521 atttatactt gtcagtataa gagactgtga caaatgtagt gatcctcaga agttaggtct
     5581 ggaaatctaa cttgagaaga tttttttaaa ctacgtccag tcttttttat ttgtttaaaa
     5641 ttgaagttga caagtcttca ttaaaaattt agaatattca caagtttgac gacaattatg
     5701 aaaatttatg tcgtgctaaa ggagttttgt tattggatga aaagttagat ataaaaactg
     5761 cgatcaaaga cacgttacct accgtttttg gttatatcgg tattggactt gcatttggta
     5821 tcgttgggaa agctgccggg tttcatccgc tggtcgtcac gttgatgtcc ctgctgatct
     5881 atgctggttc tgcccaattt atcacggtca gcatgcttgc tagccatagt ccactgctct
     5941 ccatcgttct ctcgaccttt ctagtcaatt cccgaatgat tctgatgagt atgacgattg
     6001 ctccttattt caagaaaaat cggctgcttc aaaatctgct gattggcaca ttgctgacag
     6061 atgaaagttt cgcactggga atgaataaat tgaactatac tggacaaaag ttaaactttc
     6121 gttggatgaa tacagctaat tggatttctt atttgacgtg ggtgggttct tctcttgttg
     6181 gcgcactttt agggaatttt attactgatc cgaaaaagtt tggtttggat ttcgccatcg
     6241 tcgctatgtt tatcgggtta ctttatcttc aagtcatttc tgatagaaac acctctaaac
     6301 gattacagtt gatcctgatt ggtctcactt tgattctggt atatgtcgga ctgattttta
     6361 tcccaagtaa cttagtgatt ttagttgtaa cactgattgg gtgcggattg ggggtgtgga
     6421 tcaaacatgc cttcttttga gtttacattg ctgactattt taggttgtac tttagcaact
     6481 tggctttcta ggatcctacc atttgtctta ctgaaaaaat tcgatttgcc gcaaccgttg
     6541 cttgagtatt taagttttgt cccgatcgtc attatgtctg ctttatggtt cagcagtcta
     6601 tttacccaaa atatcggaca tctgccgcag atcaatctcg aaaatgcttt ggcttcagtt
     6661 cctacacttt tagctgctat tctttcaaaa agcttattgg tgatcgtctt ggtaggaatt
     6721 ctttcccttt cgttgattcg cttattataa ataaaaaaac aagagcttat ggcaaattac
     6781 tgtcatgcgc tcttgttttt atcaaagtca aataagaaaa aaatcggcgt attcttgctt
     6841 atccgttgaa cggaccacta acaacgactt ttcctaatat atgtcctgtt tctacgtctt
     6901 tggttgcttg tttcaagttc ttcgcattca tcccatctga atagaccttg ctcaatgtac
     6961 tgcggataat cccttcattt gctaaagcag caatgtgcgc taaagcttct ccttgcgttt
     7021 cgatttcata gttatagtct gttttagcga acatatactc ccagtcgaag ctgatagatt
     7081 ggtttttcca aacacctata tctaacggct ctttgatccc tacgatcgtt cccacatgtc
     7141 caaatggtcg gacaaggtgt ttgatttgat caaagtagcg ggtaatatcg aataatacag
     7201 cgacatactc tacttgatcg attcctaatt cacgaaaact tttacttaag tcgtgatgat
     7261 aatcgattgg atagtctaca cctgtttttt tcagccattc aaaattcttc ggacttgcag
     7321 tcgcgtagac ttctaggcca gcccaatgcg ctagttgatt caaaatcgaa ccgacgcccc
     7381 cagctccgtt gatcactaag atttttttcc cgcggttggc attttcttct ggagtcagac
     7441 caaatttttc aaataacaat tcataagcgg tcaatgaggt caacggcaag gctgcggctt
     7501 cttcatctga aagatttttt ggtgcaagag cgacaatacg ttcgtcaacc agttggtatt
     7561 cttgattgct tcctgctctt gtcgttgtac ctgcgtaaaa aacgcgatcg ccgacagaaa
     7621 atttttgcac ttcatcacct acagcaacaa ctttcccgac tccatcaaac cctaagatac
     7681 gtaaagcatt tcttatcccg ttatcttggc gaagtttcgt atcgacagga ttaacagata
     7741 ctgcgttgac ttttaccaga agatcccgtg aactgggtac aggtatctgt tctttttcat
     7801 caataaagct ttttggatca tcgatcgaca acccttcata aaaaccgact accttcatta
     7861 attccttttc tgacatacga attcctcctt agcttcatca agttggagca tccatacagt
     7921 tttcatttca atatatatag tatgctattt gttccacttt tattcatcat aattattctc
     7981 ttacttaaag taaactattt gcactttttt ggttaaaaaa gaggttgcga caagactttt
     8041 gtcacaacct cttttaaacg gtgttcaatc aactgaccct cggtattcgc tcaaaaaacg
     8101 acaaaatatg aggagctatt tttgtttggc tgttcttatt acttgatgca ggacagcttt
     8161 ttcacgacct ctaattcacg gtgttcaagc aagaaatcat tgttcactga aaagcgttgg
     8221 atgttctttt tcaaaggtgt ctaagatctc tcgtacttca tcagtagatt tcgtattcat
     8281 caactgaact cgcaagtcat ttgctcctgg aaatcctttg atatagattt taaagaaacg
     8341 atgtagtcct gtgatggaac gcgggatgat ttctgaataa tgatcttgca gatctagttg
     8401 cagacgaagt agtccgatca gttctttttc tgtatgttcc ctcggttctt tttcaaatgc
     8461 ataaggattc ttgaaaatcc cccggccaat catgatgcca tctacgccat atttttcggc
     8521 caattcttct cctgtctggc gatctgggat atctccgttg atcgtgatca gtgtttgcgg
     8581 agcgatttgg tcacgtaaag caatgatttt agggatgact tcccaatgtg catctacttt
     8641 actcatctct ttacgcgtac gcaaatggac agaaagattg gctatatctt gatgaagtag
     8701 gtgactgatc cattcttcca tctcagacat ttccgtatag ccgatacgcg tcttgacgct
     8761 gacaggcaaa ccgccagctt tagccgcttc aatcaattgt gccgctactt ctgggcgaag
     8821 gatcaagcca ctgccttttc cacgttctgc tacattaggg actgggcagc ccatgttgat
     8881 atcgattcct tggaagccca tttctgccat agcaatgctc atttctctaa aaaattctgg
     8941 cttgtctccc caaatatggg caaccatcgg ctgttcatct tctgtaaagg tcaatcttcc
     9001 tcgtacactg tcttttccat ctggatgaca gaaactgtct gagtttgtaa actcagtaaa
     9061 gaagacatcc ggtgctgctg catgctttac gacatggcga aatacaacat ctgttacatc
     9121 ttccattggt gctaaaacaa aaaaaggctt tggcagctct ttccaaaaat tagtagtcat
     9181 ttatttgtta ctctccattc tatcaagcag tgaagtcgca atctttctca aaaacattgt
     9241 cattatacta ggaaacaaaa aaagaagcaa agtgaacagc ttaaaagatg tttctgattg
     9301 agcaaaaaaa gactgtgaca aaaatcttat cacaattcct tttccggaat aaatggtgtt
     9361 caaaagcttg catctgcggt aataagtcca accaaacgaa aaataggagg agctattttt
     9421 gtttggctgt tcttattact tgatgcagaa cagctttttc acaacctctc cactaaacgg
     9481 tgttcaatca gctgaccctc ggtattagct caacaaacga caaaatatga ggaactattt
     9541 tcccgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc ttttctaact
     9601 tctcaatcct cttcctttat tgatcaaata ccaagtaacg gcgtacaaaa caacgatgaa
     9661 tagcacaagt acgatcatcg atgttgctac tggcacatcg attgttccaa ggaatccgta
     9721 acggaaaccg gagatcatat aaacgatcgg attgactttc gaaacagctt gccaaaatgg
     9781 cggcaacata gagatggcat agaaaacgcc acctagataa gttaacggct gcaagacaaa
     9841 tgtaggcacg atcgatacat cgtcataaga ctgagcaaaa atcccgttga gcagtcctgc
     9901 taacgaaaac aagattgccg tcatcaataa tgtaatgatg accatgaacc atgaatacac
     9961 atgaagtggt acaaagaaca aggaaatgat cgttacgaga gagccgacga gaatactgcg
    10021 acccactccg ccaatcacaa agccccaaat gatcacatgc gtaggaacag gcgctaccaa
    10081 gatttcttcg atgtttttct ggaatttttg agagaagaag gacgaagaaa cgttggcata
    10141 cgaactagtg atagcagaca tcataatcaa accaggcacg atgaattcca tatatgaaaa
    10201 accacccatg tcaccgatcc gaccaccgat catttttccg aaaataacaa agtacaagga
    10261 tgtcgtgatc acaggcggaa ccagtgtttg gacccagata cgcaaatagc ggttcgtttc
    10321 cttgatagct aaacttttta atgcagtaaa ataaagatta aacatttttc tcctccgtat
    10381 gattattttc ttctgtgatt ttcaaaaaca gttcttctaa acgattcgac ttattcctca
    10441 tagaaagaac tttgattcct tgtcttgtca gctgatcgaa gattccgttc accccttgat
    10501 ttcgttcaac ttcgacagcg attgtctgtt catcttcaaa tgtacaagcg tatccttcaa
    10561 tcacaggttt ggtctcatat ggcgctaaat caaagataaa tgtttcaaat tgcagtttgg
    10621 atagaagctc tttcatacta gtattctcga tcagttcacc tgattggatg atcccgatgt
    10681 tgcgacaaag catttcagct tcttctaaat aatgcgtcgt caaaatgatc gttgtaccat
    10741 tttcgttcaa ttctcggaga aactcccaca tctcgcgtct caattcaata tcgactcctg
    10801 ctgttggttc atccaagatc agcaaacgtg gttcatgcat caatgcccta gcaatcatca
    10861 gtcttcgctt cattcccccg gaaagcatac gtgcacggac atttctcttt tcccaaagat
    10921 tggactgctt caaatatttt tcgctgcgtt tcatcgcttc tttgcgagag acaccgtagt
    10981 agcctgcttg attcacgacg atttgctgga ccgtttcaaa gggattgaaa ttgaactctt
    11041 gcgggactaa tccaatctgt tgctttgctc ggactagatc cgtatccaga tcataaccga
    11101 agacattcac ttttccagat gttttattga ctaaagaagt aatgattccg atcgttgtag
    11161 acttcccagc tccatttggt cctaatagcg catagaaatc tccttctttc acggaaagat
    11221 cgattcctcg caatgcttcg accccacttc cataaacctt tttcaaatta tttatttcaa
    11281 gcgcatttgc catttatttc ctatctcctt atagacatga ttctttattg tatcatggaa
    11341 tacagcagat gaaaaaacaa cttggttcca gcgaaaaatc aggttgctgg gctcaggaaa
    11401 atctcctaat gaaagacatc aatcggacga agtcagacaa ccttttcaga aaaaacaaat
    11461 cgaagataaa ggattactat tcatatgtgc aacaaaagga gcgtgagaca aaagtaaaga
    11521 acacttttgt ctcacgctct aaacacgtat aaacggcgga agcaaaagcc aagatttttg
    11581 atccaataaa tactttcgat cacttcgcct atcccaatac atgccactgc cgcttttcat
    11641 caaataacgc ggcttccgtt tttgcggttt ctactaaagt ctctgggtaa tccaaaactt
    11701 tcagcaaggc aatcgcattt cgggtccttg aaggtccttc ttttaatttg aaatcaaaac
    11761 tgattccttt tccttctgtt acttgttctt caaagtggac attctcacaa taattcttta
    11821 aaatctctgt caattcgata tcatgtgtgg cgacaaatgc taaagatgga tactccgcaa
    11881 gccaccgaac gactgaagcg gaagaagcaa tccgttcgat cgtatttgtc ccttttaaaa
    11941 tctcatctac gaagcagtag cagcgttctt tggaagccac ttggtccaac aaacgtttga
    12001 tcgatttgat ttctgaaaca aaataactgt cgccttcaaa taaatcatct tcgattgcca
    12061 tggaagtcaa cacatgtcca ggttgcaggg taaactgttc tgcaatcgct gtttggatcg
    12121 tctgtgctag aatacagctg atggctatac ttttgacata cgtagatttt cctgatgcat
    12181 tggaacccgt gactaatgta ttcttctgcc agttgaccgg attcactacc gcttctttta
    12241 acaatggatg atagatatct ttcgctgtca caccgccctc agtaaactct ggtcggcaag
    12301 tgatgggcat ataagtacgg taattcaata ttgcagcggc tacttctaat tctcccagca
    12361 attcccacag cttgatggct tcagttgaat gcttttctaa tttagtgaga acgaaatgat
    12421 aggagataaa tggcagcatg aacatgatgt tgacatattc aaaaatcaac tctgcttcac
    12481 tcccactctt catacgaaat gaaaaaccta atttagggat gtctcttaat ggtttagttt
    12541 gctgtttcag ctcttcttga agtggtgtcg gcagttttgc tagctgattg gcggctgaaa
    12601 tcgttgaaac caaataactc atgctattca gctctgtttc tagtgtttgt ttcttcacta
    12661 gataatagac cgtattgaat actaacccac cgattgccaa atagattcct agtacttgtc
    12721 ctaaaagaag caaacccaaa cccaccagcg gaagcaagcc aagaaaaata aataaaccta
    12781 cgcgtccaat ctttttactt tttccatccg ctagatattg ttttgcaaaa ttatgatctt
    12841 tttttcctaa acgagcgaat tgatattgga ttttttctct cagttgagga ttttcctgat
    12901 aaaaagcaat cagtttttct aactgctgat cttcaccaaa atcaaagctg cgtaaacgtt
    12961 gatacaacgc ttctgaacct acactagaat aggtactgtt gattccttcg aatacttcga
    13021 acatatccag gtcataccaa gtaagatcat cgatttcgct atcccatgaa cggaacttct
    13081 tctccgtgag ccatgcttcc ttcaagcttt cttctttatc aaatctcggt tgataaggaa
    13141 ttttttccca tttgctacga actgtttcct ttaatttcaa acgtgaaaaa atgtctaaag
    13201 caactaataa aataacagct gcaataataa ttaaaacgat aaattctctt tgacccatat
    13261 ccctctccgt tcctttattt gttagcttta gtatagcact gttgcgctat ttgaaaagag
    13321 ggtaaaaaaa cacctttcaa aataaaaggt gtttttttct tgtatattac atatttatct
    13381 ctcatttatc aaaattgaca aataatcata gggaggaatt gttgttaatt cttgtttatt
    13441 ctccagtgca ttgacaactg tcccaaggga aaggatagcc tcaggtacta ttttttcttg
    13501 ttctgttgga ttagctaagc gaagaacaaa tccttgttca tgaaaataag aaggataaat
    13561 cgatgataca attaagtctt caggtaattc aatcaatgaa aatttacgag gaacatcaag
    13621 ttcattttgt aatggccaaa tcttgttatc taacctgtga ataaatacat tcagtttctg
    13681 cttttgataa gaaatagatt gttctaaccg tttttctgcc tgttttgcca ctttgaactc
    13741 attaaatctt ccttcttcta cattaaatcc aaaagtgact ttatactcac ctatctcttg
    13801 agctagcggt gtttccatca tgacatgccc ttcatttgtc gtatctcctg aagctcgccc
    13861 aggtcgccaa gcaagattag gttttccaag ttcccctgtt gttgaaaata aggttatgat
    13921 taattgattt tctatacgtt catactcttt taaaccatct gcataaaacg taaaataatg
    13981 atcattttct gccacagaga cactcttatc gaatatttct aaattaacag gtttctctac
    14041 catagtttct gaccaattcg gaggaatgac atcaggggta ttttcaataa atccgttttg
    14101 aatttgtgca attgattttt cagatttatc taaaacatta attgctaagc gcatacgatg
    14161 cgagtaaaca gtattatgaa ttttgagtgt gccttcaacg atttgacttt ctcccagact
    14221 gaacgatatt tcataagata tttcttccat ttcgggtttt tcagataaac gatcttttaa
    14281 atctttagga agttgagctt ttccgtaaac aactaatgtt tcttgtaaag aatctttata
    14341 tactttagct gtttctaatt ttagagatag ttctgtatct ccttctaatg gtgaataatc
    14401 atacgtatcg ccatcatttg ctgaatcgat caaatgaacg aaatcaagat attgtctatc
    14461 tccaactatc aaattcaatt gcccatcttt aaaagaaagt ttatatttat tgttacttat
    14521 ctcagttttg tctatctcga ttgctgtttc taatttttca ttatttttct caaattcaac
    14581 aacagtgtat cctagtgctg gcacatttac atttattttt atgtcaagtt cataataagc
    14641 tggttcatca aaatattcga aacctgtagc aatcatccga taagcatttt tccgttctgg
    14701 aaaataaact tctttttcaa tgatattata gggactacct ttgaagtgta ttttctttga
    14761 atcagctact acatgcacga ttttcgatcc actataattc tcagtcgttg tgttgaaaac
    14821 aaggacttca ttcgatttta gctttaatgc atcagccatc cgttttacaa taaggttttc
    14881 gattccgtca gctatctcat tagcttcttt gattcgatgg aaaatatctt ccgcaacatt
    14941 atctgaaaca cagccaccaa tactatcatg agcctggttt tgcaaaatct ttttccataa
    15001 ccgacgaagt aggcctttac tgatatggat accatttctt tctgcaatca gcatgagcgg
    15061 ctcaactcgt tttagaattt tttgttccaa tttaaaattt tctattttca tttttgttct
    15121 tactgagcca atagaacgat gaacacgaga gtaaaccggc tgacgaagtt cacctttata
    15181 ttcaggtaat tcttttttgt ttctgataac ttctacataa gaaggataat ctgaaataat
    15241 attgtggaat ttactgtatt tattcaactt ctctacgact tgatcaaaat ttaaaatcat
    15301 tgacttttga tctacacccg aaggtactaa aatatctttg ttttttcctt gcatatgaag
    15361 catttcaact gcttcatcca acttttcttt tgcaaattca ggaatatctt taattgcgtc
    15421 taaggtcatc attccagtca tataaccaaa tggaaaattc atggcataaa caaatttatc
    15481 tcccaatcct ttccagataa aataaggaga tggaaccatc gtttcaaagt ttaatcctcg
    15541 ccaacacatg aaattatcga tttctacttg atgcaaaagt gtaggcaaat tcgcattgaa
    15601 cccaaacgtg tcaggcaaat accctaccat cattggatct ccatatttaa ggatcgtatc
    15661 actgattcca atcattaagt ttcttaaaat tgattcagca tccactaata aggcatctgt
    15721 ttgtgcatac cacggtccca cgaatagttg tcctgttttc atcagtcgtt ggataacctt
    15781 aagcttttgc ggattgatct ccaaatactc atcgacgatt gaagtttgtc catctaaaca
    15841 aaagtttact ttagggttcc tttccaattc atctagaact tcagtaaaga cctgatcaga
    15901 caatacgatg gcatcttcat ttgtaaaata ccattctctg tcccagtgcg tgtgttgaat
    15961 tatatgtgca tttaccatat cagattctcc tactttcctt cttctactga atttacttgt
    16021 tgttcttttt tatacttgat ggattttagt gcattgacca ttaacgctgt aaccactccc
    16081 ccaataacaa ttgatactaa atataaaggt atattcgtaa caaaaggaat tgccataaag
    16141 gttgaaagca ttgtttcttg agtaacacca aaaaatccat ttagaccaca tgctactgca
    16201 gtgcccacca cgatgcttgg tattactcgt aaaggatctt tcacggcaaa cgggatcgtc
    16261 ccttcagtaa tccccacaag gcccataatc atagctgtct ttgcattatc tcgttccgat
    16321 tcatcataaa gttttttgtt taaaattgtt gctaaaaaca ttccaaatgg cggaatagca
    16381 attcctaata acatggctgt actaggtcca aagcttccgc ttgaaaaaga agcaacccca
    16441 aaagcatatg cgattttatt gataggtcct cccatatcaa acgccatcat tcctcctaaa
    16501 atagccgaca tcaaagcagc atttgctcct gacatgcctt ctagccaatt agtcagtcct
    16561 gttgtcattg cttgaatagg cgtagctagt acataccata atatgattcc aacaactaat
    16621 gtagtaacaa aaggaatcag cataattgat tttagactaa taacttgcat cggtactttt
    16681 acttttttca atgcattagc taaatagcca caagctaatc cagcaaccat tcctccaata
    16741 aatcccatac caagattttg acacatcatc ccagtgataa aagctggtgc tagaccggga
    16801 cggtcagcaa ttgaatatgc gatataggct gaaatcatcg gtacgataaa ctgtaatccc
    16861 gtctgaccaa tcattcgcag gactccccag aatgtatccg tctggtccca aacacctgtg
    16921 ccaccaaaaa tgactgcaat agaagttagt aaccctgctg ctacgacaag cgggatcata
    16981 taggaaaccc cactttggaa atgatttaga atttctcttc cttgtttctt gaattccatt
    17041 agtaactccc ccacgatata ttttttattt gttaattaat gcaattgctt catcaatcgt
    17101 ctcttcacca tcttttacta cctctgaggt ccctactgtt aaaatcggtt taccgtcaaa
    17161 gcgacctcgt tctgaaacat ttgtatctac tgcaaatatg acaacatctg cctcggaaac
    17221 atccgaaatt gaaagtttgt tttctatccc catagccccc tgtgtttcta ctttaatatc
    17281 taaccctttc ttcttcgcaa acttttctaa attagctttt gccatataag tatgggcaat
    17341 ccctgcgata catgctgtta ctgctactat ttttgtcata tgaaattcct ccttttaaaa
    17401 tgatagagct tttaccaatt cttttttatt tctcgaatct tttattcttt taacaaactc
    17461 gtcatccatc aatcttccag ataattctgc taaaatacgt aaatgattag tacctttatc
    17521 agtgtctttt attgctaaca aaaagacgag atcaactggt tgatcatcta atgcgcccca
    17581 ttcaacagac cgctttaact tggctacagc cactgttgat tcaattactg ctaggctttt
    17641 gccatgagga atggcgatat ttttcccaat tcctgtggtc atatggtttt ctctgtcaaa
    17701 tacgtctttt tgaaattgtt tgtggtcaga cacaaaccca ttagtctcta acaatttcga
    17761 taatttttcg actacacttt ttttatcaga t
//
LOCUS       DAFTHM010000052        17709 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFTHM010000052 DAFTHM010000000
VERSION     DAFTHM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17709
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.052"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            26..931
                     /locus_tag="L7C88_001709"
     CDS             26..931
                     /locus_tag="L7C88_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBP9558528.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            1022..1699
                     /locus_tag="L7C88_001710"
     CDS             1022..1699
                     /locus_tag="L7C88_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBP9558529.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            1696..1866
                     /locus_tag="L7C88_001711"
     CDS             1696..1866
                     /locus_tag="L7C88_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558530.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            1980..2876
                     /locus_tag="L7C88_001712"
     CDS             1980..2876
                     /locus_tag="L7C88_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBP9558531.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(2931..4301)
                     /locus_tag="L7C88_001713"
     CDS             complement(2931..4301)
                     /locus_tag="L7C88_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9558532.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            4539..5285
                     /locus_tag="L7C88_001714"
     CDS             4539..5285
                     /locus_tag="L7C88_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBP9558533.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQPVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            5282..6121
                     /locus_tag="L7C88_001715"
     CDS             5282..6121
                     /locus_tag="L7C88_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBP9558534.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            6122..7072
                     /locus_tag="L7C88_001716"
     CDS             6122..7072
                     /locus_tag="L7C88_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBP9558535.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            7213..7965
                     /locus_tag="L7C88_001717"
     CDS             7213..7965
                     /locus_tag="L7C88_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558536.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            7984..9135
                     /gene="queG"
                     /locus_tag="L7C88_001718"
     CDS             7984..9135
                     /gene="queG"
                     /locus_tag="L7C88_001718"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBP9558537.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEVYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            9519..10127
                     /locus_tag="L7C88_001719"
     CDS             9519..10127
                     /locus_tag="L7C88_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBP9558538.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            10295..11932
                     /locus_tag="L7C88_001720"
     CDS             10295..11932
                     /locus_tag="L7C88_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBP9558539.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(12004..13116)
                     /locus_tag="L7C88_001721"
     CDS             complement(12004..13116)
                     /locus_tag="L7C88_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBP9558540.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWSTEDYQKDISTYITKNPS"
     gene            complement(13191..14564)
                     /locus_tag="L7C88_001722"
     CDS             complement(13191..14564)
                     /locus_tag="L7C88_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9558541.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            14785..15402
                     /locus_tag="L7C88_001723"
     CDS             14785..15402
                     /locus_tag="L7C88_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBP9558542.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKPFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQLVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            15500..15955
                     /gene="argR"
                     /locus_tag="L7C88_001724"
     CDS             15500..15955
                     /gene="argR"
                     /locus_tag="L7C88_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBP9558543.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            15973..17475
                     /locus_tag="L7C88_001725"
     CDS             15973..17475
                     /locus_tag="L7C88_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBP9558544.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
BASE COUNT         6114 a         3202 c         3664 g         4729 t
ORIGIN      
        1 actaaaggag taaggaggga tagacgtgga gcaatcgatt tttttaaaaa aggaacatca
       61 acaagtagaa aaagaattgt attttgattt ttgtggtttc tctaaaacga tgccgtttca
      121 ttcttttggt cctgctattc gcaatgatta catcctgcat gtcgtgatgg aaggcaaagg
      181 atcttatcat gtgaaaaatc aacaattcca attgaaaaaa ggtgatctgt tcttgattcg
      241 tccaggagac tcgacgtttt acttatcaga tggagaagat ccgtggatgt attgctggct
      301 ttcatttggt gggagtgctg cagaagaaat cattcggcag tcgcttttca gagaagacca
      361 atacacgatg gtctcttctg acatacaaaa atatatcgac attattttag aatgcatgaa
      421 agatacggaa gaaaccttgg aaaatgaatt acagttaaca gcattaacct accgtttttt
      481 atcagtcctt ttaaaagatg gcggaaaggt cagcggtggt gtacaaaagg ttcattcctc
      541 tttagctgtt gaaacagtca aatacatcga ggcacattat gctgaaaaat tgtctgttga
      601 ggaaatcgcc cagcatttag cggtcaatcg gagccatttg tcgcgagtat tcaaaaatca
      661 tatgggtacc agtatcaagg aatatttgat cggggtacgg atcaatcgag gggcgtttct
      721 tctttctctg acggatgaat ccgtggaaag tattgcctat caagtagggt tcaatagtct
      781 agtcgtattt agccgaatgt tcaaaaagag taccggagaa acggctacga actatcgtaa
      841 acgtatgaaa aacgaaaatt ttaagaatat tgctttggat accttgaaaa aacagttgga
      901 aaaacaaacc gcagtttctt ggacaacctg attagtctgg ttaaaatgac aagcatcggc
      961 aaaagaaact tgtggcggtt atgctacact gtaaagcgaa gactaaaaag gaggaaaagg
     1021 gatgcgtaca cttatcatca ttagccatcc aacgatcgaa gaatctttaa atcagcaatt
     1081 tttcaaagaa gcttctgctg gtttaccagc tacttggcat catttggaat caagttatcc
     1141 agacggaaaa atagatatag agactgaact acagctcttg gcccagcatg atcggatcat
     1201 tttccagttt ccgttttact ggtatagttc tcctgctcat ttaaaaattt ggcaagataa
     1261 tgtcttggaa cgagcagcac atgtattaaa agggaaagaa ctaggaatcg tattgacaac
     1321 aggtgtggcg gaaaaagaat accaagctgg aggaaaagaa gaatatacga tttccgaatt
     1381 tttgaggccg tatcagcgaa tcgcaaataa attccatatg acctatcttc cgccattcgt
     1441 tttagcacaa tttatgtatt tatcccagga aaaacgttgg gagaagctaa ttgcttatca
     1501 gcagtatctc tcattggaag gcaaaccatc gctgactcag cggattgact ggtttattca
     1561 aagagtacag gaaaatcaga aaatgcagga agaagaatct gaaaaacaag catatatcgt
     1621 agaagcactg actgaggcaa aagagcagat cgaagacttg acctttacac tgcaagaaat
     1681 gaaaggaact tcattatgac aaatgattgg ctgatccaac aattagatga attaagcgaa
     1741 aaatcagaat atcaagaccg tgcgctctta tatgaaataa agaaactgat ggctgagata
     1801 gacgaacgaa caatgcagct gcaaggagaa atcgacggac aatcttggaa tcatctcaac
     1861 tggtgaaatt ttcttataaa taacaaagat aaaaatgtgc acagcgacaa ttatttgcta
     1921 caataagaat atgaagcgtt tgataacgct attatacata aaaattggtg gtgaaaaaaa
     1981 tgtatgatga aaatgagtgg ggagaaaatg ttcggatgac ccgaagaaga cagcaaaaac
     2041 aggcagctcg taagcggatg atcatgattg gggcagcagt tgccgtgttt ttgatcatag
     2101 caggaggagt tgcgggtcta tattttcatg gaaaaaattc gtcagaagcg aaaagtacga
     2161 ccataacgga aacaacgaca aagaaaacag agacgaaaca aacaagtgag tcatcaacta
     2221 aaacaaaaga gacacaaact tctgaagaaa aaacagcaaa tggtttgcca gagcaacttc
     2281 aagcaatcgt aaatgattat tcgaaaaaga tcgaagaaaa gacgcctgca ttgattgaag
     2341 aataccagac agaaattcag ggaaatcaag agggaatagc tggtttatca gcagttgcta
     2401 accaaaaagc acgtgagctt caagcaatct ccgacgaagg gatcagaaaa ttacgtgcag
     2461 cgtatcaggc agcagaaaat aaagacggtg tagacttaga tactttgatc aatcaattat
     2521 cggctaatta tacgaatcat gtcgctaaga tttccgatat ttatttgcag actagcgcct
     2581 ctcttcaagc agagtcaaca agcacacaag acacaacatc ttctgattct gagacagcag
     2641 agtcggtaga agcttctgaa atgcaagctc gaacaacaca agacacaaca gattcctctg
     2701 aaactaatac caacagcgcg acttcacagg ctgcgacaac cgtagttttg gaaggagaag
     2761 gtccaaatca aatagccgaa cgaactggcg taccagtaga aacgatcttg tcgctgaatg
     2821 ggatgagcat ggagaattat ttcctgactc ccggtgagac gctaaaattg aattgataaa
     2881 agcaataaaa aagaacgaag cttccactaa ggtgaagctt cgttcttttt ttattttccg
     2941 gttctttttt cgcgtacaaa gtaatggatc gtcatgtaaa gcaagaaaac gagtccaata
     3001 atcaatgaga ttctcgtttc aggattgata aacatgaaaa tcaatacgat agctaaaaaa
     3061 gcaagtgtca cataattcgt ataaggagat agtggcattt taaaaggatg atcatgcatt
     3121 ttatctgcgt gcttcttttt gaagcgaatc tcgctgatca aaatcactac ccaaggaacc
     3181 ataccaggca aaatacttga gctgtatacg aaaacgaaaa tattttctga ctggttgatg
     3241 aacattggta gaagataatt taagatcaga ccaattaaga ttccacctga gattgctacg
     3301 acaggataaa aaggcgcacc gtgacgagat agtttcagaa attttttaga catctttcca
     3361 tttatggcaa gtgtatagac catacgactt gcgctgaaaa tccctgaatt gcaacctgat
     3421 aatgccgctg taatcacgac aaaattaatc agtcctgcag caaatgtaat gccgacttta
     3481 gaaaaagttt gtacaaaagg tgaaccaatc tcactcaatt gattccacgg atagatactc
     3541 acaatgataa aaatagcacc aatataaaaa atcaagattc gaccgatagt ggactggaca
     3601 gcttcaatga tcgtcttttt aggattctct gcttcaccag cagtcattcc gatcagttcg
     3661 attccttgat aggaagcaac aacgatcgat aatgcaaaga aaaatccttt gacgcctcca
     3721 gtgaagaatc caccattttt ccaaagattt gaaatcccta ctgcctgacc atgattacca
     3781 aatccaaata agattacccc aagacctgca atgatcatca aaatgatcgt tatgactttg
     3841 atgatcgaaa accaaaattc taattcgcca aacgccttga cagaaataag atttgccagc
     3901 ataagaaaca agacgacaat gattccggga ataattgccg gcaaatcagg ccaccaataa
     3961 ttcatataag atcctacagc aatcacttca cttattccta cgacaatata ttgaaaaata
     4021 ttactccaag cggtcaagta gccagccaca ggatggatgt actcgctcgc gtaatttgca
     4081 aaagaaccag tcgaaggatc aacgtaaagc atttcgccta aagcacgcat aatcaaatac
     4141 aaaaagaatc ctgcaatcgc ataggctccc atcactgagg gccctgtcca acgtatggtt
     4201 gaggaggcac ccataaacag accgacaccg atcgttccac ctagtgcgat catttggata
     4261 tgacgggcac taagacttcg agttaacttt tcttcttcca tacaaaaact cctttcgttg
     4321 ttgagtcaac aagaaaaaat aatcaaacgt ttcaacacat gtttttcatt attaggttag
     4381 ccttattgaa ctcttgatgt gattctacag aaaattttca taaaatgcga ggaaaattcg
     4441 aaaaaaactt tttcatcatt ctacttgaaa atgctttcca ttttagttaa actatattta
     4501 aataaaaagt taggtaaacc taaaaaggag tgtaagattt ggaacgtacg gccattgtaa
     4561 ttcaagacct ttcagccgct tatcaaggga aaactgtttt gaaaactatc aacttgacga
     4621 taaatccaca aaaaattacc ggtattatcg gaccaaacgg tgcaggaaaa tcaacattta
     4681 tgaaatcttt gctagagttg ataccagcta ctactggtaa agtcaccttt tctggacagc
     4741 cggtaaactc agtccgtaaa aaaatagcct acgtggaaca gcgaagtgaa ttggatcttt
     4801 cctttccaat tgatgtatta ggcgttgtac ttttaggaac atatccatct ttacgaattg
     4861 gacaaagacc tgggaaaaaa gaaaaagaac gtgcaagaca agctttgaaa aaagtaggga
     4921 tggaagaata tgccaaaaga cagatcagcg aactatcggg tggacagctt cagagagttt
     4981 ttattgcaag agctctagcc caaggagcag aatggatctt tttagatgaa ccattcgtag
     5041 ggattgatgc gttaagtgaa cgaaagatct ttgacatctt gcaggaattg aagaattcag
     5101 gaaaaacgat tttgatcgtc catcatgatc ttcataaagt agaagaatat ttcgatgagg
     5161 ttattctttt aaataaacag ctgatcgctt ccggtccagt acaagaagtc tttacatcga
     5221 agaaccttca attggcctat ggtgagatca tcagacattt agtaaaagga ggagagaaaa
     5281 aatgatccaa tcctttattg atggattaat gaattatcaa ttcctgcaat acgctttggt
     5341 cacttccatg cttgtaggac ttgcttctgg agtcatcggt tcttttatta ttttacgagg
     5401 gatgtctttg atgggagacg ctatctctca cgcagttctt ccaggtgtag ccatttctta
     5461 tatgtttggt tttagttaca tctttggagc cactgctttt gggatgctaa cagcagcagt
     5521 gattggtttc gtgactcagc ggagccgatt gaaaaatgat acagcgattg gaattgtctt
     5581 tagctccttt tttgcattag ggattatctt gatttcatat gcccagagtg cgacagattt
     5641 gtatcatatt ttatttggga atgtcttagc tgttagggaa agcgatttgt tgctgacagc
     5701 actcgttagt ggaatcgtct tgatatttgt ctttttcttt tataaagaat tgaagatcac
     5761 atcattcgat ccgacaatgg caaaagctta tgggctgaac acatcgctga tccattatct
     5821 tttgatgttc tttttgacat tagtggctgt agtcagttta cagacagtag gaacaatctt
     5881 ggtgattgcc atgttgatca caccagccgc cacggcttac ttgctaacga accatttact
     5941 gaaaatgatc attacagctg caggaatcgg tatgctaagt gcagttgtcg gtgtgttttt
     6001 cagttatagt tacaattggc catcaggagc tacgatcgtg ttagcatgta ccgcattttt
     6061 tatccttgct tttttatttt ctccaacaaa aggaatttta tttcagaaag gaagcagata
     6121 gatgaaaaca aaaaaatcac tctttttaat cttggcagtt agtttcttgg tattagccgg
     6181 ttgcggaaag caggcttctg accaagcgga tgaaggaagt aaagaaaagt tgtcagtcgt
     6241 ggctaccaat tcgatcttgg cggacatggc aaaagaggtc ggaacagatc aaatagatat
     6301 ccacagtatc gtaccagtcg gaacagatcc gcatgaatat gaagtactac cagaagacat
     6361 caaaaaggca agcgatgcag atgttatttt atacaacggt ttgaatcttg aaacaggtaa
     6421 cagctggttc gataacttga tggaaacggc taaaaaagaa gaaggaaaag attattttgc
     6481 agttagcaaa aatgtagaac ctctttattt aactagcggt gaagaacata caaaagcaga
     6541 tccccatgct tggctagacc tatctaacgg aataaaatat gtggaggaaa tcgcacgtat
     6601 attctctgaa aaagatgcag aaaatgcgac actctataaa aaaaatgcag aagcatatgt
     6661 ggaaaaacta aaagaattag atacacaagc gaaggaaagt tttgcttcta tcgaagagaa
     6721 caaaaaatta ttagtaacaa gtgaaggggc attcaagtat ttttcacgag catatgattt
     6781 gccagcagct tatatatggg agatcaatac agaaagtcaa ggtacgcctg atcaaatgaa
     6841 agcgatcatt gatcagataa gagcaaaaga agtaccggtt ttattcgtgg aaaccagtgt
     6901 agactcaaga agcatggaac gggtagcaaa agaaacgggt ttgaaaatct atgataaact
     6961 gttcactgat tccatagcaa aagaaggaga acaaggagat tcttactatc agatgatgaa
     7021 atggaatatt gaaacgatcc atgaaggttt gtcacaaaca aaagaaagct gaaaagtgca
     7081 aggtctagct tgaggagcag accttgcatt ttttataaga gatatgaaaa aaaattatgc
     7141 tgtttttcgt cgtacagata ccttttttga agaaattccg ttatagttag agtaaggaag
     7201 gaaggtgtgg ctatgaattt tacacgtaaa gataaatata cgattaaaga agaagtcttt
     7261 cgattgatca gccagcagga aaataccgac aaggatcaag accttcaatt tcttgaagca
     7321 gaattagcta aattattcat agcaaatcaa aatgagacaa cagaaccaga tgaagagctg
     7381 tacataggca aatggttgtt tgatgaattt cagcctttag atgaaaatac cggtatcggt
     7441 tattttgtgt tcctttctcc agtcggcttc acacctggcg tattagttaa acaaaacgac
     7501 gaaataaccg tcaaagcatg gcctgcatta ttttcagtca tcaaagcaga aggagtaatc
     7561 aaaaagatcc agtcggccta ttataaaagt caatttattg ccaacagcaa attaatgaat
     7621 atgttttata atcgtctagt agaaattgct aggcctggga aaatcccgca aacattcacg
     7681 tacacacagc aaaaaaatct ctatgaagaa gtattgtatt cccgcgatct gtctgagttt
     7741 tcgccatggg aagaggtaag gctccatgaa ctgttaagta caaaaccagt ttcattgaat
     7801 ttttttaatg cattagataa caaaagaaaa ttaatttcaa caaattattg ggaagtattt
     7861 gctgcaagaa aaaaatggat ggaagaaaag aagattgccg atcagcagat ccagtttgtc
     7921 cagctgaaaa aagaaaaact atattatggg ttatacagcc gttaacagca agcgaggaag
     7981 accatgacat taaaagaaga aatcatacaa gaaagcaaac gattaggaat tgacaaaatc
     8041 gggttcacca cggcggaacc ttttgattca ttaaaagaat cgttggaaga acaaaaagca
     8101 gctggccata cttctggctt tgaacatcca aatatcgatg agcgtcttta tccagaaatg
     8161 acatttgatc agccgaaatc gatcatttcc attgcacttg cgtatcctac taggatccat
     8221 gaagaagtgc ctagggatga aaaacgcggg cagtttgctc gtgcttcttg ggggatcgat
     8281 taccatgata tactcagaga ccgtttgaac cgattgatcg aattcatcca aacaagagca
     8341 gaaaaatggc aaaaagaaga ggaatggcgt ctagctccgc aagtagatac tggagaactg
     8401 atcgatgtcg ctgtagcaca gcgagctggt ttaggattta ttggacgaaa cggattgttg
     8461 atcactgaag agttcggttc atttgtctat cttggtgaga tcgttactaa tattgtattt
     8521 gagcctgata aaccaggaga atttggttgc ggtgactgta tgcgctgcgt gactgcttgt
     8581 ccgacaaaag cattgcttgg tgacggaaga atgaatgccc agcgatgttt gtcttatcaa
     8641 actcagacaa aagggatgat gccggaagaa tatcgtaaaa aaatgcgaaa tgtcatttat
     8701 ggatgtgata tctgccagtt agtctgccct tacaatcaag gaaaagattt tcattttcat
     8761 gaagagatgg aaccaaaagt agacgaagta tatccaaaat taaagccaat gctttcgatg
     8821 tctaataaag acttcaaaca gcaatttggg catttagctg gttcatggcg tgggaagaaa
     8881 cctttgcaga gaaacgcatt gattgcttta gctaatctag gtgatcgaac ggcattgcct
     8941 gagatttcag aatgtttaac agatgtccgc cctgtcatca gaggaacagc agcttgggct
     9001 attggacgtc taggaacaaa agaaccggaa aaatggcttg atgtattaga tgaaatatta
     9061 gctaaagaaa cagaagaagt cgttataaac gaattggaac atgcccagaa attattgcgg
     9121 agaaagttaa aataaaaaaa tagttaacat tattcaaagt ttttgtccag taattgttgt
     9181 aacaattact ggtttttttg tattttttac atttttttaa gagaatttga taaaaatcaa
     9241 aaattttttt gctttttttt atggattatt gcagtgaatg ttacagaatc tgcgtttttc
     9301 attcaaaaat aaaaaaacat agaaaaacga ttactttgct tatacaacaa ggcttttatg
     9361 gttttgtatc aaaaaaatat ttgtttaaat gttacaaata ttaaataatt cgttattttg
     9421 tcattaaatg tcatgtttct tttacctatg aaatatttct aaatgataaa gttaatagcg
     9481 tcgaaagaat aaaaaacgga gaaaaaaagg agtttaatat gaattcattt aagaaaattg
     9541 ttttaggtac aacttttgct gctggtgcta ctgcaatgtt tgtaggaact acaaatgctc
     9601 acgctgatga agtttataca gtaaaatcag gtgattcatt atctaagatc tcacaaaaat
     9661 ttgcaggaga caactcaatg atcgatgcaa ttgctgaaaa aaattcgatc gcaaacatca
     9721 accgcattta tgttggtgaa caattaacaa tcccaacttc aaatgattct tcagcaacaa
     9781 cagaaaacaa aacaacagaa aatacagcat ctacaactga aacagcaacg caagaacata
     9841 catacgttgc acctgttgaa acagttgaag tagctcctgc tgccccagct gctgcaacag
     9901 cgccaacttc aagctctgca aaagaatgga tcgcacaaaa agaatcaggc ggttcataca
     9961 cagctactaa cggacgttac atcggccgtt atcaattaga tgcttcatac ttaaacggcg
    10021 actattcagc tgccaatcaa gaacgtgtag cagaacaata tgtaacatct cgttatggtt
    10081 catgggatgc tgctaaaaca ttctggttag caaacggctg gtactaagcc gataaaagga
    10141 aaatgatgaa accgagaaac ttgtttattc aagttctcgg tttttttgtg tgaaaaataa
    10201 ctcgtttgct tcccacagcg cagcagtaca aataaaaact cgaataatgt ataataaaga
    10261 aaacgttttt ttgtttaggg aatgaggagg agccatgagt acaaaagaga gtctcgaatt
    10321 aaacgaaatc acaagtggaa atccactgtt atccagtatt cgatcgattg tagaaacgac
    10381 attttacggt aataatgttc atgaagtttt tgacaggaag acagcttatc aactagcaaa
    10441 agggagtcca ggaacgatca tcacagattt aacaatctca catgctgaag aactagattt
    10501 accagctgat gttaggacac tagtattcaa tgatggaagc attgtgggaa gaacagcaag
    10561 tgctcggcgg atctttgagg acttagacaa ggaacaaagc aaatacgaga aaattttaag
    10621 agaagctgtg tatcaaagtc gcaagcgcca gttttaccat acaaaagtaa tcgttggcct
    10681 atctgaagaa ttttctgtgc aaagtcattt gctgattcca gaaggatttg agaacaattt
    10741 gtattcttat ttgctgaatt ttcagccagc gaattcgaag atcttagaga cttatcaaaa
    10801 gtctgtttcc tttgatgagg gagatcttta tatcttttgt gatcccgaat ggacacatga
    10861 aacatttcca aatggactca ttttgtttga tgctctccat aatacagcgg ctgtgctagg
    10921 attacgttac tttggagaat taaaaaaagc gactttgacg cttgcttggg cattgggaaa
    10981 tcgcaatggc tttattgcct gccacggtgg gatgaaacaa tatgctagta atgaccagac
    11041 ctatacgatg gctgtatttg ggttgtccgg ttctggaaaa tcaacgatta ccttagcaaa
    11101 acatacggaa ggtcactctg tttcgatctt gcatgacgat gctttcgtta tttctcgaaa
    11161 aaatggtttt gctactgcct tggaaccttc ttactttgat aaaacacaag actatccgtc
    11221 tgatgatccg gccatttctt ctttccttac ttgtcagaat gtgggcgtga catgtacaag
    11281 taaaggagaa aaagtcctag taacaggaga tatacgaaac ggaaatgggc ggacagtcaa
    11341 atcacgttat gcgacacccg accgagtcga tcatcttagc gaaaagatcg atgctgtttt
    11401 ttggatcatg aaagatgatt cgcttccgcc aattatcaag atcaatgacc cagttttagc
    11461 agcgtctttt ggtgcaacat tagcaacaaa acgatcagac gcggaaaata tcactacaaa
    11521 aagacagcta gatgagctag tcattgaacc atttgctaat cctttccgtg tctatcctct
    11581 tagggaagac tatcaagctt ttcgagagtt gtttttgaaa cagcaaacag cctgctatgt
    11641 cctgaatact ggatatttcg atgataaaaa aatcaaacct gaaacgacat tgtcaatcgt
    11701 tgaaagaatc gtgcaacaaa cggcagaatt caagtcgttt ggtccatttg aagacatcca
    11761 ctatttacct ataccagatt ttcctgtttc ttttgaggat acgtcctata aaaatctggt
    11821 gaaacaacga cttgatattc gtttacgatt cattgaagct cagataggaa aagatctctt
    11881 gccagatgaa gcaaaagaaa gtttggagaa tttgattcag aaattgaact aaaataacag
    11941 ctttttcaag aagtaatcca tgcgcaatat cgctcgggat ccttacttga aaaagctgtt
    12001 tttctatgat ggatttttcg taatataggt ggagatgtcc ttttgataat cttccgtaga
    12061 ccaatgacca gtatttaaga agttggctaa tagatagccg atataaggac ctgtggtcaa
    12121 gccagaagag cctagaccgc tagcagccag taagcttgga tcatctggca gtacgccgaa
    12181 aaatggggaa aaatctgacg tataagcacg ggtacctaca cggaactcgt atggccagtt
    12241 ttttatctga tctggatcag tcaagaactg ttctgtactc ttagtcaatc ccttataagc
    12301 ttcgctagta ggagccaaat cccagccttg atcgttttca tgggtagcac ctaaaaggat
    12361 ctttccatcc atgaaaggaa tgaaatcagc ttctccgtca agcatagcaa caggccagtc
    12421 ttgactcatc ttataagatg tctgaaatgc taagagctgc cctttttgcg gacgtatatc
    12481 tgcagcatag cctaattctt gtaataaagg cttaagtgcc gggccaggtg tcaaaattac
    12541 acgatcagct gtgtattctc caaacggtcc cttgatgagc caagaatcgc tcttcttatg
    12601 caaagtgact tttgcctgga tctgctccat ttgtttttgt gctaaacgct gaccaagatg
    12661 ttctaaatat gcttttccat ccagacgacc accaccactg atacgcagtg aaactgctgg
    12721 tttcaataac ggaagtgctt gagatgtctg ttcaggtgaa agccattcga tgtttccaat
    12781 ttctggcgct tcttcttttc gtttctcggc aagaacagcc aattcagcta aatctttttc
    12841 aggtcgaagc aaaagtgtcc ctgattgtgc gtaaatcgtt tgatcaagtt ggaaatcttt
    12901 tataagttta gggaaaaaag cagcgccgtc tttagccaga cgataccatt gtttgtttct
    12961 gcgtttcgac aaccaagggg agataatccc agcgctagct ttagttgcct gtcctgtccc
    13021 ttcatcaaat aaagcaacat tgaattttga tgtatctaag taactggcta gagtcatacc
    13081 aatgatcccg ccaccgataa tggcaatttt ttccataaaa aagcctcctt ttacaaacaa
    13141 ccattttcac acaaaaaaac ggcagatgca acacctgccg tatatggaat ctacgctttt
    13201 ttagcaaaga acagataata ggcgaatcga gcaaagctta cgagaagcaa cagcaacaag
    13261 acgcctaatg ctgcttttga tcctaatgta gtagacactt catagttatg ggaagtatga
    13321 tgctggacgt aattgataat gaccgctact aatgaagtag ccacagcgcc agaaaactgc
    13381 tgcaaggtat tgaacattgc gttcccgtct ccttgtagtt cttcattcag tgcattcatt
    13441 ccggtggtca tcatattgct gtaagataat ccgataccga tcatataaaa cacatgacaa
    13501 gcaatcaata cacccactga agcgtgtcct atgagtagga ataatgctag ccaaccaatc
    13561 aaagaaagaa tcagcccagc aaaaattggc ttcttcggac catattgatc cagcattttc
    13621 ccggaaaaag gagaaagcaa agcaccaacc gctgcgccgg gaagcatcgc taatccagcg
    13681 acaaaaggac tacttccttg aacgatctga aggaaattcg gcaagacaaa agatacacca
    13741 agtaataaaa actgataaac taagaagcca atcaaaaaca agcggaatgt tttatttgaa
    13801 agaatagaca gtcggatcag tggatgctcc acttttttac ttcgatagta aaaaaggaac
    13861 cagccaatac cgccgatgat taaagcaatc cagctggaaa ctgttcccaa cgtactcaaa
    13921 aatgttagac ttccactaaa caaaagacaa attcctaaaa cgcttatcca atccaaataa
    13981 ccactttttt gtactgccat ctcgggaata gcaaaccagc cgataatcaa agaaagaatc
    14041 aaaacgggca caagaaacag gaagatatga ttccatgtaa aatgtgaagt cataatgcct
    14101 ccataagtgg ggccaattgc tggagcaatg gccgttgtca aagtaccgac acccatcatc
    14161 gcgcctcgtc gattgagggg ggcaaatgtc aagataatat ggaacatcaa cggaagagcg
    14221 atacctgtcg ctgcaccttg gagcaatcga ccaaacaata ggaccatgaa ggtaggagag
    14281 aagaaatcga tcattatacc tgccaagaaa agcagatttg aagctaaaaa gagttttttg
    14341 agactaaaat tgcgattcaa ataagtagac agcggaacaa tgatcgaaat catcaaaaga
    14401 taaatcgttg ttacccattg gacttgtgca gtcgttaaat caaactgtct gataagagtt
    14461 gggaaagtta cattcatggc cgtctcgatc aatacgcccg caaaagacat catccctgtt
    14521 gcaattactg caggtactaa aagcagctgt ttttgttttg tcatttacat cacctctaaa
    14581 aaatttcgta aaaaaagaga gtgatttcta ttataaaaat agaaaccgcc tctctctcga
    14641 cacgccgaaa cgtgttatct gtacgattta tttacttcac ttattctagc acaaactgaa
    14701 aaatagtgtc aacacgatta gccaagtcac tcaaaaagag gtatgataat aaataactaa
    14761 atggaatttc gcggaggaag aaaaatggaa aaaattgaat ggcgtaaaga caagagctat
    14821 agtatgaaaa aaagcccgca aatactagag gttcctaaaa aaccattctt tagcatcaga
    14881 gggatcggcg acccgaatca ggaagacttt aaacgaagag tagcctgtct atatgcagtc
    14941 agctatgcaa tacgcatgtc gcctaaaaaa aattggctga ttcctgatta tcagatgtat
    15001 actgtctatc cactggaagg acaatgggga ctgcaagaaa agtatttgca tgaaccagtg
    15061 atgaaaaaag aacatttttc ttatcaattg atgatccgac agcctgactt tgttacagaa
    15121 gcgatagcac aagaagccat tcagcgttct agcaaacttc cggaagactt gaaagaacaa
    15181 ctagtattca aaaagatgga agaaggtctt tgtgcccaaa tcttacacgt cgggccctat
    15241 gccgaagaac cagcaacgtt tgagaaatta gaagcattca tcgcaaaaga aggctatgaa
    15301 agagcttcta aagaacacaa agagatttac atcagcgatc caagaaaatc agcacctgaa
    15361 aaaatgaaga cgattttgcg tgttaaaata gaaaaaggtt agcaacctga atgaaaacaa
    15421 aaaataaaag taaaaaatac caaaatatga agaaatatta cttatctttt gctataatca
    15481 acattgagag gtgtctaata tgaaaaagaa acagcgacaa gcactgatcc gccagatcat
    15541 tacagaacaa cctattggga cacaggaaga gctgcttgcg cggctgcatg aagcaggcgc
    15601 cgatgtgact caagcaacga tttctcgaga cattcgagaa atgaagttag taaaaagtca
    15661 aaatgaaaac aaaatagtac gctatacatt atttaaccag ccatctgttt ctttaaatga
    15721 agaacgtttg cgtacagcaa ttagacgcga ggttttgcgt atccagtctg ttcagttcat
    15781 ggttatcgta ttgactgaac gaaatggtgc cgatgtggta acgaattggc tagatgaagt
    15841 ggcttaccct gaagttgtcg gaacgatggc cggtgtagat acattcatta ttatttgccg
    15901 ctcagaagaa gaagcacagc gatttgcaga aaagctggaa aaaatgaggg aataaatgag
    15961 gaggactttt atatgaaaga tatgaaagcg ctgcaaaatg gatcggatat tcgaggaatc
    16021 gcattaccag ttgaaggata tgaagtaaac ttgacgacag acatggtaaa aaagatcggc
    16081 tggggactag caaactggat aaagaaaaag aagaaatcaa ccgatccaaa taaaaaatgg
    16141 acgattggga ttggtcatga cagtaggata agcggaccag cactgaaaga ggcgttgatc
    16201 caaagtctga aagaacaagg gatacatgtc atcgatttcg aattagctac tacgcctgct
    16261 atgtttatgt ccactcaatt tgaacagttc tcgtgcgatg ctgcggttat gctgactgct
    16321 agccatcttc cctattatta taatggaata aaattcttta cctcagaagg aggagcagaa
    16381 aaagaagata ttgcttttat cctatcacag cagcaaaaaa taaaaagcga acaaactgga
    16441 agcgtagaaa aagcagacct tttgacacct tatgcgcaag atttagtcac aaaaattaaa
    16501 aaggggattg gaacactaga aagcaaacca ctaaatggtt ggaaaatcat tgttgatgcc
    16561 ggaaatggtg ctggtggatt ctttgctgaa aaagtattga atagcttagg tgcggattca
    16621 acaggttccc aatttttgga accagatggc cgatttccta atcatatccc aaatcctgat
    16681 aataaagaag cgatggaaag tatcaagcag gctgttttag caaatgaagc agatcttggg
    16741 atcattttcg atacagatgt ggatcgttct gcagttgtca gtgcttctgg aacagtgatc
    16801 aatcgaaata atttgatcgc agtattaagt acaatcgtat taaaagagca tccaggaaca
    16861 agaatcgtga cgaattcccc tacttcttct catctacaaa gattcattga agaaaaagga
    16921 ggcatccaag ttcgttatat ttccggctat cgaaatgtaa tcaataaagc attagaactt
    16981 aaccgtcttg ggaaagatac acagctagcc atcgaaacaa gcggacacgc tgcattcaag
    17041 gaaaactatt ttctggatga tggtgcatat gtcatcgcaa agatcctgat gcttttgcca
    17101 gaattaaaaa gaaaaggtat cacattagat gaacaaatca aagagttgaa acagcccgta
    17161 gaagtacaag aaatccgatt aaaattgttc agcgatgaac cacgcgaaca aggaaacaag
    17221 atattagaag aaatgaagcg actgttggaa gaagaaaaag ggatgaactt cgacccggaa
    17281 aatgaagaag gtattcgata tgatctagaa gagccatacg gaaacggctg gtttttgatc
    17341 cgtttaagct tacatgagcc gttactagta ttacagatag aaaatgatga attcggaaag
    17401 aacaagttgg cgttagtaaa attagcaaaa ttattcggac atttttctga tcttgaatca
    17461 ttaacagcag aataaaccag tctttttgaa aggctagttg cttggacggc aaaaaaagtg
    17521 gtatggttaa atcgagtgct ggtagggaga ccagcaaaag gaggaaaaaa tggtaacgaa
    17581 tatggttatt tttttaacag tattggttta tggggtcaac tttctggtat atatgtatct
    17641 taaaatcaat catataaaag attatgtaga aaagattgct atttattttg gaacaaatat
    17701 gacgctgtt
//
LOCUS       DAFTHM010000053        17592 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFTHM010000053 DAFTHM010000000
VERSION     DAFTHM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.053"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..270
                     /locus_tag="L7C88_001726"
     CDS             <1..270
                     /locus_tag="L7C88_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBP9558545.1"
                     /translation="PKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFC
                     VPDSFSNYRISREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            616..990
                     /locus_tag="L7C88_001727"
     CDS             616..990
                     /locus_tag="L7C88_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558546.1"
                     /translation="MEDKMYLRQKVFTKKDIENQINGFIQKLENANSYLINKELNKAY
                     DQWKEVYDELKLIQNETKLVRTEKKNENSFFFDGYAILMLETVAKQNIKAPKKELSDN
                     IDNALAELRYYVMQIKDVRITR"
     gene            1027..1194
                     /locus_tag="L7C88_001728"
     CDS             1027..1194
                     /locus_tag="L7C88_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558547.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKH"
     gene            1220..1564
                     /locus_tag="L7C88_001729"
     CDS             1220..1564
                     /locus_tag="L7C88_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBP9558548.1"
                     /translation="MNEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            1569..1850
                     /locus_tag="L7C88_001730"
     CDS             1569..1850
                     /locus_tag="L7C88_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558549.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            1953..2267
                     /locus_tag="L7C88_001731"
     CDS             1953..2267
                     /locus_tag="L7C88_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBP9558550.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            2245..3939
                     /locus_tag="L7C88_001732"
     CDS             2245..3939
                     /locus_tag="L7C88_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBP9558551.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNANLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            3959..5137
                     /locus_tag="L7C88_001733"
     CDS             3959..5137
                     /locus_tag="L7C88_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBP9558552.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            5100..5786
                     /locus_tag="L7C88_001734"
     CDS             5100..5786
                     /locus_tag="L7C88_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBP9558553.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            5786..6946
                     /locus_tag="L7C88_001735"
     CDS             5786..6946
                     /locus_tag="L7C88_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBP9558554.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGRLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            6956..7831
                     /locus_tag="L7C88_001736"
     CDS             6956..7831
                     /locus_tag="L7C88_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558555.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWARLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            7828..8139
                     /locus_tag="L7C88_001737"
     CDS             7828..8139
                     /locus_tag="L7C88_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558556.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            8129..8482
                     /locus_tag="L7C88_001738"
     CDS             8129..8482
                     /locus_tag="L7C88_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBP9558557.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            8472..8873
                     /locus_tag="L7C88_001739"
     CDS             8472..8873
                     /locus_tag="L7C88_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558558.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            8866..9270
                     /locus_tag="L7C88_001740"
     CDS             8866..9270
                     /locus_tag="L7C88_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558559.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            9282..9890
                     /locus_tag="L7C88_001741"
     CDS             9282..9890
                     /locus_tag="L7C88_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBP9558560.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            9910..10272
                     /locus_tag="L7C88_001742"
     CDS             9910..10272
                     /locus_tag="L7C88_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558561.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            10275..10457
                     /locus_tag="L7C88_001743"
     CDS             10275..10457
                     /locus_tag="L7C88_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558562.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            10474..13893
                     /locus_tag="L7C88_001744"
     CDS             10474..13893
                     /locus_tag="L7C88_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBP9558563.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNTLAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     VTAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQEIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWSSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSVFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGESGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRTQAVQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            13944..14681
                     /locus_tag="L7C88_001745"
     CDS             13944..14681
                     /locus_tag="L7C88_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBP9558564.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            14691..16982
                     /locus_tag="L7C88_001746"
     CDS             14691..16982
                     /locus_tag="L7C88_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBP9558565.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKALAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLHHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            17006..>17592
                     /locus_tag="L7C88_001747"
     CDS             17006..>17592
                     /locus_tag="L7C88_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558566.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIQKYNETFDAFMAEIEGRVDSLNKQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSI"
BASE COUNT         6269 a         2561 c         3708 g         5054 t
ORIGIN      
        1 ccaaagcacg gcaataaggc agaagacgcg atcattcaga tgatggatat agaagcggag
       61 agagatgcga ttctagcggc tttgatggct cttagtctaa ttagtcgcca gatactctac
      121 tacagcttct gtgtgccaga tagcttctca aactacagga ttagccgtga agtgggttat
      181 tcagaaagaa gtatacaacg gatgaagtcg gaagctctaa tagagtttgc agaagcatat
      241 aaacacggaa gaataattgc ttataaataa tttggcggtt ttttggcgga atgatggcgg
      301 tttttagcta tttaccagtg atattatggt agtgtcgaaa gattagtgat aggtctaaga
      361 caaaataaaa tgtaagggag gaaatctccc tcatcgttta attaagcttc gatagacagc
      421 agcaaataaa ctaaaggatg tgggggtcag ctcctacagt tagttcatgt gttgctgtct
      481 attaattgca actctttcgg ttttattgag tatttactca acttaaaaaa actgttgttt
      541 gtagatgtaa gctgttccta tttgtacata gtaaaaaatg atataataaa aatattacga
      601 aaggggtgag agtgcatgga agacaaaatg tatttaagac aaaaagtttt cacaaaaaaa
      661 gatattgaaa atcaaattaa tggatttata cagaaattag aaaatgcaaa ttcttatttg
      721 ataaataagg aactaaataa agcttatgac cagtggaaag aagtatatga tgagttgaaa
      781 ttgattcaaa atgaaacaaa attagtacga acggagaaaa agaatgaaaa tagtttcttt
      841 tttgatggat atgctatatt gatgttggaa actgtagcaa aacaaaatat aaaagctccc
      901 aaaaaagaac tatctgacaa tattgataac gcattagccg agttaaggta ttacgttatg
      961 caaataaaag atgttaggat cactcgttga gtggtctttt tattttgcac aaaggaggta
     1021 acaacaatgt atagaccaca atacttagaa cagaagtatg aagtaatcac tgtgcaaaat
     1081 ggtaacggag agatagtacg aaagtataga agaccaataa agagcgatac atataaacga
     1141 aaggaaagca atgaagttat tccattgtat ggcaaaagaa tagctaagca ttaaataaga
     1201 ttgtgaaagg agacgggaca tgaacgagga attctataga tggctattac agttgataag
     1261 agaagatcgt ttggttaagt tctatcagtc tcctaaatgg cgcaggctta gagagaaagc
     1321 gatgaaacga gatcactatg aatgccaaga gtgtagaaga ctaggtaagt atcatagagt
     1381 agagaacgtt catcatataa aggaagtcaa ggatagacct gacttagctt tagatttaga
     1441 taatcttatt tgtttatgtg ttgaacatca taatgaagtt catggcagat atcttacagc
     1501 attggataaa caagagaaga agatagaaag ctttgctaac ttcgatgcaa gtgaaaggtg
     1561 gtaagtgcat gatcatcaat gataatggca gagagtatga tacagaaaag attgaagagt
     1621 attcatctta tactcaggga ttaattaaac gtttgatata cgttcgctat gtaggtatta
     1681 gggatctgtt atcagataac tgttgtagta aatacaaagt gaatcaagta agagaagcgt
     1741 tgaataaaga taataacgtc gaaagaataa aaaatgtttt tggatatagt attgaagaga
     1801 ttaattatta cattgacttc gctgaagctt tcattccgat ggtgagataa ccccccctta
     1861 aaataaatcg caaatttttt gggggtgatg aaacggaggg ggctgtcagg aaaagagatt
     1921 ttttcgaact ttatcatgaa aggagggcta aaatgtttaa aaacgaattg tctcaaaatc
     1981 gctacagaga aaaattacgc cgctctttaa taagccaatt ggaaagtcag aaaacaaata
     2041 ttgagccatt cttagataat gttgatcgtt atatcagttt atgggaaacg gcgatatcac
     2101 tggaagaaga tatatccgag aacggcatta gactggagaa tggtaaaaag aatgaatcag
     2161 tagcgttgct tgtttctgtc aacaaacaaa tgggattgat gttggataaa cttgccatta
     2221 ctcctgaatt ggtaggtgaa gcaaatgaat caattcctga gttataagca tattgaaaat
     2281 tggttcaaag ctatagaaga aggcactatc aaggtatgca aagagcaatt attgctaaaa
     2341 aattatctag aagaaagagt ctttactaga gaagatattt acttcgataa gcagatggta
     2401 gaggattcaa tcaatatacc agcacaatac tttccattcg aattaattcc gtgggaaaaa
     2461 tttctacaat gttttattta tggtgttcga tggaaaaaag ataaaacact agtgttcaat
     2521 agatatcttt cattaatggg acgtggtaat ggtaaaactg gttttgcttc ttggaacaac
     2581 ttctttctac taaccgctaa acacggtatt aaaaattatg atattgatat ctatgccaat
     2641 aatgaaagcc aagcaaagac tagttttgat gatgtattta aagtaattaa agatcatcct
     2701 gatttagata aaaaagtatt taaagctacg aaggaagtta ttcaaaatat cgctacaaac
     2761 agcaaacttc gttataacac ggcaaatgct agaacaaaag atgggaagcg accaggtgca
     2821 aaccgctttg atgaaattca cgaaaatgaa gattattcaa tgataaatgt ggctacttct
     2881 ggtggtggta aaattcgaga ttatagagaa ttttatgata caactaatgg tcatgttcgt
     2941 ggtggtccgc ttgatgacat tatagaagaa tcaaaaatga ttctttctgg agaacttgga
     3001 attgacaagg atggagcaga attttctagt ttgtttccat ttatttgtcg cttggataac
     3061 gataatgaag ttgatgatcc cgacatgtgg gaaaaagctt gtccaactat taattacaat
     3121 gcaaatttaa aacggaaaat gtttcaagaa tactctcaaa tgcaacgtaa tgctggttta
     3181 agacttacgt tcatgaccaa acgaatgaac agacctatgg aagatacacg atttgctgtt
     3241 gcttcatatg atgatgttct gcatacgaaa gaaaaagaat ttcctgaaaa aatggatgaa
     3301 gtgataggaa cagtcgattt tgctgataga cgagattttg ccagcgttgg gttgctagga
     3361 aaatacgata aagatgttta ttttacacaa catactttta tccacgaatc agcccttcga
     3421 ttacaaaaca tcaaacgaga ggttatagat atttctatag atcaaggaaa atcacagatc
     3481 gttcatggaa aaaatataga agctgattat attgtaggtt ggtttcttga aatgagtaat
     3541 aaatattata ttaaaaaaat cgctatggat atgtaccgtg caaaaatatt gaagcccgct
     3601 ttagaagaag caggttttac tgtggaaatt gttcgaagcg gatctgttac acatggtatg
     3661 ttaaaagatc tggttgatga cctttttatt aatcaacgtt tattttttgg tgacgatgcg
     3721 attatgcgtt ggtattgcat gaatgtatat gaagagcata tttctaatgg aaatatacgc
     3781 tatgaaaaaa tagaacctga aactagaaaa acggatggct ttttttcatt ccttcatggt
     3841 ttgaattttt tagatgatat ttatgattct gctcctgtaa cagtcacaaa tagctcagta
     3901 gaaaatacag gaactggatt tactcctcta gtattctaac ttgaaaggag gtgagaaagt
     3961 ggggattttt caaaaggcgg taggatactt cacaaaaaaa gcaacggttc ctttagaaga
     4021 atacttttgt aaattgcaag ttgattttgt gtatcgaaaa tttgcgattg aaacttgtat
     4081 tgatttgatt gcaaatgcga tgagtaaagc ggaattcaag tcatatgaag atggaaaaaa
     4141 taaaaagaat gatctttact ataggctgaa tgtagctcct aataagaaaa ataatgcaac
     4201 agaatttaga aaaaaactga tcaggagatt aatattctac aatgaagtat tgatcgtttc
     4261 tccgtctaat aattctagcg aaatatttat tgcggatagt tgggatgtca cagaatatgc
     4321 attgaaagat gatgtgtttt ctcaagtgca aattaacaac atagtccttg atagagaatt
     4381 tctagaaagt gatgttatct atataaaata cgcagatcaa caaattaggc aactagtcga
     4441 tgcgtattat caagcgtatg ggaaactcat ttctagtgcc atgaatgttt acaagcgctc
     4501 taacgctcgt agatacgtac tgaaagggaa tttattccga ccgcaagaca atacaacaca
     4561 agatcaaatc aataaaatga tgacatcaca atttaaggct tttatggaag ctgataatgc
     4621 aggtgcggta tttcaattac aaaatgagta cacattagaa gatttcagcg gaaacttcca
     4681 aagcaattca agagatataa aaaacttaat agacgacatc tttgagatga cagcagcagc
     4741 gtttcacgtt ccgaaaaacc tactaaaggg agacatgagt gggttatcgg atcaagtgga
     4801 cgctttttta atgttcgaaa tcataccgat tgctgaactt attcaggatg cgtttaacgc
     4861 tagtctctat gaagtagaag aatacttgtc agggaatttt gtacgtgtgg atacaactat
     4921 gatcaagatt actagcttca aagatttggt tgacgctatt gatgtaggca ttagaaatgg
     4981 agtatttaca atcaacgaag gaagagaacg cgttggaaat gatcgctctg ataaggcgat
     5041 ggcagatgaa atatttataa ctaaaaacaa tcaacaagta tcgaaaggag gtgaggcgaa
     5101 tgacgacaat gaaaacattt ctagcagtaa agaatgaagg cgcagtaccg caaattttta
     5161 ttcagggatt tattggttct agttggttct ttgaagggaa tactgacaag ggaatcaaaa
     5221 atattttgga tagtctaggt gatcaagaag aaattgaagt agtaattaat tcaaacggtg
     5281 gagacgtatt tcaagggatt gctattggga acttacttaa gtcaaataaa gcaaaagtta
     5341 acgttgtgat taacggctta gccgctagtg ctgcttcaat tatcgcaatg gctggcgata
     5401 ctataaaaat ctacaacaat gcacaattga tgattcaccg cgcttccaca tacggagaag
     5461 gaaatgtcga tgacttccgt acgattgctg accaactgga atcaattgat aaatcggtaa
     5521 aggcttcata taaaacacga ttcaatggca cagatgaagc attgcaagaa cttcttgaaa
     5581 aagaatcgtt tatggatgca gaaacagctt tgagttatgg attggtcgat gaaattatcg
     5641 atgcagaaaa tagctcaggt actgaagcta aaaaagaaca aagcgttgaa gaaattttga
     5701 atgacgttaa agaaaaaaga gcagaaaaaa ttgctgcatt tacagcagca ttaaataaaa
     5761 catttggaca aggagatgta aaataatgac agttaaaaat ttaaaaggtg taacagctgc
     5821 aagcgaccaa ttgatgaaag cttttaaaga tggtaacgaa gaatctttta gcgcagctat
     5881 ggtaagctta tctaaggaaa ttcaggataa aattttagaa gaagcaacag caaaaaatca
     5941 agatcaatta gtattaatga accgtggtca gcgtgtatta actacacaag aaacaaaatt
     6001 ctataacgaa gtagtgaaaa acgaaggttt tgcaggggtc gaagaattag tgccagctac
     6061 tgtatttgaa cgtgtatttg aagatttaga acaatctcat ccactattgc aaaaaattac
     6121 ttttgttaac acaactggtg taacagaatg gattgtgtca cgtggagtca atccagcatg
     6181 gtggggtaaa ctttgcgaag ctgttaaaaa agttttagat aatggctttg atgtaattaa
     6241 catgaagcag ttcaagctat caggttatat tcctgtatgt aaggcaatgc ttgatttagg
     6301 tccagtatgg ttagatcgtt atgtccgtac tgttttagta gaatcattga gaattgcatt
     6361 agaacaagca attgttgatg gtactggtaa agatatgcca gtcggaatga tgcgtgacat
     6421 gagcaaacaa actagcggag aatatgctga aaaaaaagca gaacctatta cagctttaga
     6481 tgctgtaact atgggccgtt tgatggcgcg actatcaaaa ttcaatatcg aaggtgtgaa
     6541 tgatccgatt tatcgtaatg tgaatccttc tgatgtggtc ctaattgtga atccaactga
     6601 ttactggtct aaagtattcc cagctaagac tgtactaact gctaatggag aatacgtaca
     6661 agtattgcca gtaccagttt cagatttgca gtcaacggct gtgccagaag gaaaagcagt
     6721 tattggggta gcctcagatt acttcatggg tgtaggatct acactaaaaa ttgaagcttc
     6781 agatgaatac cattttgttg aagacgaacg catttatcta gctaaacaat atgcaaacgg
     6841 tcaacctaaa cgtaacgata gtttcattgt attagatatt agcgctttgg gaactactac
     6901 tacaactaca aaaccaacaa ccacaacaac tacaacacaa gcgtaggtga tcagaatgaa
     6961 gtatattctt tgtcagccgg caatcaatcg gtttaaatgg gagcttgaag tttgtttaac
     7021 taatctgaag aaactaggaa tcaaagatat cgtattgctt ttcagcagac acgatgatca
     7081 gattcctatt ttttttgaga aggaatatgg tgttgaagtt catgtgtacg atgatctgcg
     7141 ggacgacaaa gagtatattc cttcgattaa accatattta tggtggaaat atttagaaga
     7201 agatcattcg cgtgaggacg accgatattt ctatatcgat tcggatgtca ttttcaataa
     7261 aagaattaat ttgcgcaaat tgccttctaa agatgatgtt tggtattgta gcgactgctg
     7321 tagttatcta agtcttgatt atattagaag ctgtgaaaac ggagaaaata ttctaaaaga
     7381 tatggcaaac attgtaaatg ttacagtaga atctttggaa actataaaca ctaattcagg
     7441 aggcgcacag tgggttatta accgtcctaa agcgaattat tggaaaaagg tttatctgga
     7501 ttctaatcgg ctatatcgct accttagagg gcaaaaaaca aatatacaaa tctggacagc
     7561 cgagatgtgg gcacggcttt ggaacatgat gtatttcaat attggtccta aagttcacga
     7621 ggaattagac ttttgttttg ctactgatcc aatagaaaaa gttaaagaag taaaaatctt
     7681 acacaatgct ggagtaacaa caaacgatga agatttattt ttcaaaggga gatacgtgac
     7741 ttctacgcct tttgatgaag atttatcatt tgtaaacaag aaaaaatgct cttacgcata
     7801 tgttaaagca attaaggcgg tggttagatg acgcctgaac aagtgactga agaattgcta
     7861 atagctgtga aggataatat ttacgttacc tggaacgaag aagatgagtc aattaaaaag
     7921 atgatagcta aaaatgctgt ttatcttcaa agtaaagtga gtacaacact ttctttttct
     7981 cctgaaagct tagaatacgg attgctaatc gaaagatgta gatacgactg gaatcgtgct
     8041 ttagatgagt ttgaacaaaa tttcgctagt gagttattag gtttcattca acattatgcg
     8101 ctacaagaat atattgcagg tgatgtgaat ggcgaataat cgtagactcg aagaaacatt
     8161 caacgatggt tggttaaaga ttttgacgca aactaccaaa agaaatgaac taggaaaaaa
     8221 gattggtgta gaagatacag aaatcacttc tttaaaattt agaaatcttt ccatgagaga
     8281 tagtgatata acagctatgg atgcgatggg atcgaaatta actaagaaag taaagactcc
     8341 atttcatcca atcgccaaga aatttaataa agatcaatat tttatcgtaa tcgatagtat
     8401 gcgttacaac gttatctatg ccgattacga taatttttat atctattttt atcttgaaag
     8461 tgtgggtgaa tatggtgatt gataattcta aagaaaaaga acgtttaaat aagcaaattt
     8521 ctgctatcaa aacttcctta gaagagcatt ttggcctcaa actctttcaa gactccgtag
     8581 gcgaggatga gctacctgat gattttaatt acttcattct cgaaacagga gaaatagaaa
     8641 tgatcactga gccaaaatat agcgtgggtc aaaatctata tctaactttc tattcagaaa
     8701 atagagaaga tttaacagga gactcactag atattatttc attgattcaa aatcgttcga
     8761 ttcgttttca gagaatggat cccaatcatt taaaactaga gaaccaagat cgctatatcg
     8821 atcaattggt atttacgttt agacgattat tgaagagtga ttgtcatggc taaaaatagt
     8881 tgggagctaa aaataaatgg acatgatgaa cttcttgtgc ggatggaacg ctattcaagc
     8941 gagagcgaac gactgattaa cgaagcattg aaatcaaaag gttcggctat tgcagtggat
     9001 aggattacag aaaaaattcc tgtttctgaa gcagatttaa gaagagggca ccaacacgca
     9061 aaaaatagtc gtccacttaa gactcaatac attaatttgg gtttcatcat tagacctaca
     9121 agaaaatttg agtatttaaa atatcctgat ttggggatag gtacttctaa aagaaatcag
     9181 ccggacgaat ttatgagaag aggattaggt cttgcacttg atccaattac agaacttctg
     9241 attcgtcaat tcgataaatt aaataaatag ggggaacaac aatggctaaa acaaaaactg
     9301 tagtaacaac gttcgataac gtaagtatca aacgaattgc ttttaatttt aagaacgcag
     9361 gaaatgcaat cgcaacgaat tgtaatggac aattagatgg cgaaacagaa atgcaaacgg
     9421 tggttaaaaa atgtggagcg acagaagtaa aatcaaaatc taaaccaatc aatatgacgg
     9481 taacaattac tgcacatgta ccgatggaag tttatcgacg tttcaatggg ttgaaacaag
     9541 atggacgtat taaaccaggc atttactctt acggtcctga ttccgtaggc gaagatttct
     9601 cacttgctgc agagatcgtg gatgacttcg aagaaaatag aaagttagtt ggtatgttag
     9661 catgcacttc gaatacagga ttaacattct ctattgaaaa tggtgcggat gaagtagctg
     9721 cgttagaact agaaacaaaa gttatgcaag atgaatttgg taaattttat catgaagcaa
     9781 ttgttgcaga acttgaagaa gacttaacag atcaatggat gacgaatcta tctgctgatg
     9841 tgattaaaaa aacttcagtt gtgacaacta cggccactca atcacagtaa aaaaaacgga
     9901 ggtagcgaaa tgaacgaaga ttactcaaaa attgaactaa acgatggaac aattttgaat
     9961 ttagaaccta aactgaatat caagaaatta ttgatgatca atagagattt taacacagac
    10021 gagtttgcaa aaatgactgt gggaaaagga tccatggata tttctgttat tcaaggtgca
    10081 aaggctgtgt atattgctta ccgccaagcg aacatgactg attatatttc attcgatgaa
    10141 tttatcgata aatgggattt tgatatggct actgccagct atatttatca attgatgatg
    10201 ttcaaacaag cacgcgatgc ttatcaaaaa gaatttgaaa aagcaaataa ggaaaaaaag
    10261 cttcaaaagt aaaaatgcca aagctcttag ttgaaacgtg ggtcgatgtc tattcgatgt
    10321 tgaccgacgt tttttctatg ccttcagatt tggttttaag cgatatctgt ttagatgaca
    10381 ttttgcaaat ggcttacaac aagagtgctt atgaaggatg gaaaaactat gcaataaacc
    10441 aatctcagaa aaactaaaga aaggaggtaa aaaatggcta aaaagagaac agaagcagaa
    10501 gtaactttca tagctaacga tgacggattg aaatctacgt taaaagaaat cagtgctgaa
    10561 ttaactaaaa atagagcaga attaaaacta gaacaagctc aattacaaca gactggttct
    10621 gaatcagaca agttaggaag taaattatct tctttagaaa agcagtatga attacaaagc
    10681 caaaaagttg aagtaactag ccaacgttta gccaatgcca aaaaatatta tggagaaaat
    10741 tccaccgaag ttcagaaact tgagagagaa ctgattaacc aacaaacagc gcaacaacgt
    10801 ttgtcaaacg aaattgataa aacgagtaat acactagctc aagcaaaagg cgaaatacag
    10861 acgtacgagt ctacaatgca acagttggat agtgaacaaa aaaatgttca agctagtgct
    10921 tctctgattg aatccgaata caaaaaatgg caagtaactg ctggtcaatc agcttctgaa
    10981 tccgagaaat tagcgaaagc ccaagaatat gtttctcaac aatctgaaaa tgcagagaaa
    11041 acgatagata tcctgagacg acagttagaa gctacacagt ctgagtttgg cgctacatcc
    11101 acagaagcaa tgcagatgga ggcgaagctt aatgatgctg aacgtgaatt tgaagagtta
    11161 ggacaagctg ctaaaaatgt agatacaact aacttggacg atatcggaag caaaatagat
    11221 atgaataatt taatggaagc ttctgacgtt ttaagcgaca ttggcgataa gcttacagaa
    11281 ttagggaaac aagcagtgga ctctgctaac agtgtaggta gttcccagag taaaatacaa
    11341 gctaattttg gtttgactaa acaagaggct gaagaattaa cgaatgtagc cagagacatt
    11401 tattataaag gttttggaga atcgttagat cagtccacag atgcattgat tttggtaaag
    11461 cgtaatttag gcgatttaaa taatcaagat ttacaaaata ttacggaaca agctatggtc
    11521 ctagaaaaca ccatgggcgc tgatatggat gaaacgttac gtggtgtaaa tggcttaatg
    11581 gtcaacttcg gattgagcgc tcaagatgca atggatttaa tggtttcggg tactcaaaac
    11641 ggtttagata aaacgcacga attaggcgac aatatggcag aatatagcca attatggagt
    11701 caaatgggat attcagctga tgaaacgttc ggaatgcttc aaaatggttt agatgcgggt
    11761 gcttataacc ttgataaagt caatgactta gttaaggaaa tgggaatatc gttaacagat
    11821 ggtcgatttg agcaaaacat ggatatgttt agtgaaagta ctagaaaagc ttttgaagag
    11881 tggaaaaatg gtggaggaac acaaaaagac gttattaatt ccatgattca agattttagc
    11941 aatatggatg gtcaatacga ccaattaaat aaagcttcta caatttggtc tgcacttggc
    12001 gaagataacg cgatgaaagt tgtccaatct ttgactgatg ttaaccatac atttgatgat
    12061 gttagtggat ctgcacaaaa aatgaatgaa gattctacta ctccgttaca agaattaaac
    12121 ggaaaaatag ctgaattaaa ggattcatta gctcctatag gcaacacaat catagatgca
    12181 ctcgaaccag taattgattt tctaggaaag atggctgatg cgtttaataa tcttccacaa
    12241 ccagtacagg attatgccgt agcgattggc ggattgactg ctgcatttac tttattaatg
    12301 ccaataatag ttggcttcat ggctctaggt ggtcctacta cattaataat aggagcagtt
    12361 attactgcta ttgctggagt tatagcaatt ataaaaaact ggggcgcaat tactgactgg
    12421 tttaagggaa tatggagtaa attcactgat tggttgggtg gtacttggga aagcataaaa
    12481 gaaggtgcct catcagtttg ggatggagtc aaagaaacct ggtctggatt tgtagattgg
    12541 gttcaagaaa tttggcaagg agtttctgat tggtttggag agttatggag cggattagtt
    12601 gaaggagctt ccaacatctg gcaaggagtc caagagactt ggcaagcatt cgttgattgg
    12661 gtttcaaata tttggaacgg agtcaaagaa gtatggtcga ttatttgggc agacattgta
    12721 ggaattgttc aaataccatg gacattaata acgtcattga ttcaagctgg tattaatatt
    12781 atcgtgggta tctttgatgt agctggacag ttattaggcg cagcttggca agctgtttgg
    12841 acacctattt ctgatttcct taaaaatact tgggatacta tgacacaatg gataagcatc
    12901 gcttggaatg gaattgtaac tacattccat actatatttg atccagtagt ggcatggtgg
    12961 aatggtatat ggacatctat tagtactacg gcttcaaata tttggaactc aattagtgca
    13021 acagcttcta gtatttggaa tagtatcaag aatacaatca ctagcttggt acaagcagct
    13081 gctacagtaa ttcaaaatat ttggtcaact gtatctagtt ggttaggtgg aatttggaat
    13141 tcaatcagct ctacagcatc aaatatctgg agtagcgtga ctagtagtat aagcaatgct
    13201 ataaacgcag ctaaaagtgc cattcaaagt gtttggaata gtatatcttc gtggatcagc
    13261 ggaatttgga acggtatcaa aaacactgct ttgaatcttt ggaatggaat tacaagcact
    13321 attagctcta aagtaaacga tggaaaaaat gcaatttcaa gcggttggtc caatctaaca
    13381 ggtattgttt ccgacatatt caataatgtt aaaagcacga tagctaatat atgggaaggt
    13441 atcaaaaaga ctgttagcgc tccgattgat tggattagag ataaaatcag tagtgtcttt
    13501 gataatttga atatttctat accacatatt ccgttaccac attttaaatt gagcggagaa
    13561 ttcaatccat tgaaggggaa aatcccaaca ttgggtgttg attggtatgc gaaaggtagt
    13621 gtgtttaatt ctccaaatat tatcggtgta ggtgaatcag gacctgaagc agttttacct
    13681 ttgaaaagat ctgtgctgca agaaattggt gatcgtatct tgagtagcac ctcagtttca
    13741 tctaggacac aagcggttca acctgtgaac aattacgaat tcaatttcac aattgatggt
    13801 aacgcagatg aagtcactat gaagcaaaca actcaacaaa tcattgatag cattacaaaa
    13861 gttcaaaatg ataatgcttc ggcatggcgt taaacaggag agtatttctc ctgttttttt
    13921 agtattaaaa aggatgtgaa aaaatgactg attgtataca ttctataatc gatggatttc
    13981 ctgattattt gcataaattg gctttagctg aaagaccaac cataccttct ccaaaaagac
    14041 agagagttga aacttctgtt ttaggaaggt taggtggctt agtgcaagat tactcgtttg
    14101 aagacatgtc gtttacattg cactataact atttagagga tgtggaagac catcaagcgt
    14161 tcaagcaatc gttttatatc atgcgtcatt ggttaaacta tgcaaagaaa ttagaattct
    14221 ctgacgatcc caacgtctat tacgttatcc agactatcga tattggggat gcagaaaacg
    14281 atattgttga atggggagag ttcgatgtaa atattactgc gaaaccattc gcaagagttc
    14341 aagaagatgt acctataacc gtagataaac cacagtcatt taacttgctg aataatagtt
    14401 tagaagaaag ttttccaaag attatcatca ctccttcagc tacttcatgc cagttcatct
    14461 taaatgatta tgtgtttagt ttcgaaggct tagtagcagg aactgatgta gtcattgata
    14521 gtgatttgat gctttgctac gaagagcaat cggacggaga tattttagat cggtccaaca
    14581 aaatgaagac catgcaatat ccgacattgc aagtggatat caatcatttt aattgcactg
    14641 gtttgagcaa aatacaaatt tatcgtaacg ggttaaggta ggtgaaatag atgatcgata
    14701 atttaataac tatttacgat aaaaatgacg cgaataattt agctgaacat ttatatgata
    14761 cgcaaggttt aggcgctttg tcagactggt taacagctac tgttagcaat aaactaaacg
    14821 gagccgagat atttcagggt acttatccaa taagcggaac taatgcagat ttgattgtag
    14881 aaggacgtat tattcagtgt tatgtagatg aaaatcgagc aaaacagcgt ctacggattt
    14941 attatgcaaa aacttctgta ataggcaata cgatagaagt aaaagctgaa cctattttca
    15001 atgatataag aaaatcggtg ttgaataaat atgacagcgg aacagaaaaa atcactgcta
    15061 ctcaggcatg gcaaaacgca aaagctttag cgaaaccagc tatcccttcg cagttttctt
    15121 tctcgtcatt agtagatacg cttgctaatg tgaagataga aaaagcgaat tttttagaat
    15181 tctttggtgg aaaagaggga tctattctag atcgatttca tggggaattt cttaaagata
    15241 ataacacatt acatcatgaa aaaaggctag gtacggatca taaaatcaaa gcgatttata
    15301 ctaaaaattt aactggtctt gacttagaga tagatgctca aagcgtttta gttggagttt
    15361 atccattcat tagcagttct tcagaaggag aagacgagat cactctacca gaagaagtca
    15421 ttttcacgga ttacgtggat gattatcctg ctggatatgt ttcttttgtt gattttaaag
    15481 acaaagcgac tgatgtagcc acattaaggg aagctgctaa agactggttg aaaacaaaca
    15541 tagataaaca aaaaccacaa gtgagtggtt cgattgaatt agtaccattg aggcatcaaa
    15601 gaggctatga aaaatttgtt gatctagaaa aagtttcgat gggtgacgga gtagatgtgt
    15661 atcatccaca gttaaaagtg aatatgtcag cgagaattgt ggaatatacg tttaatgttc
    15721 taaccaattc atacgataaa ttagttgtag gaaacgtcaa aacaaacttc ttagaaaaca
    15781 cagagaataa tgtaagcaat ttgattaatg atgccattga tcaattgaaa aatggtggcg
    15841 aaatcagtga tttaatcaat gatattgtag atcatcaaac tgatatgatt actggtcaaa
    15901 atggtggtta tgttttatta gatcctaaag aagcgcctag tcgtattttg attatggaca
    15961 caccagataa gaataccgca aggaatgttt tacaaatcaa caatgctggt attggttttt
    16021 ctaaaactgg cattaatgga acatatgaaa ccgcatggac attagatggc ggattcaatg
    16081 cctcgtttat tacggctggt gaaatagtag gaattactat tagaggtact acattaatta
    16141 gtgatggcac tgattataga acaagtattg ctaatggcaa aatgacttgg tactcaaaaa
    16201 aagttaacaa agatattatg gagctagaag cacgtgatta tgtaagtgct gatgccggta
    16261 ttgtatcata caccatgaaa actggtggtg gtttcatgat tagaaatcca cagggtaact
    16321 tggtttttag tacgtgggat aatggtaata acagaccgtt tctatctttt ggtgcgccca
    16381 atttcaggta tagcaatgct agttatgtaa cttctggcga cggtagttct ttaagcatta
    16441 atggtagtgc gggtaactca tgggaattta aggtagctgg taggactatg aaatttacta
    16501 gtgatggtat gctaacgttg ccaggttgtt tttttggttc atgggaagat gggaaacttg
    16561 ctaggtttga acaatcaacg gtacaagtat ataaagattt tactgttaga ggtactaaaa
    16621 actcaaccgt accaacagaa cattatggac aacgactatt aaacgcttat gaaactccag
    16681 aatattattt cgctgattat ggggaagccg ttacaggtga tgatggtaaa gttcgtgttg
    16741 atattgaccc catgtttgct gagacagtaa atctaagtcg atatatgaca catgtgacac
    16801 ctacagaact agttttgtgt gctgttactc atgaagatat tgaccatttc atcattgaaa
    16861 ctagtaagcc aaacgtatta gttagatgga atttagtggc acaccgtcta gggtatgaag
    16921 atattagatt aaaagaggat acagcatatg atagcacagt gcttgaccaa aaacgttttt
    16981 aaaacgaaga caaggaggta tataaatggc tagcagttta tataatttgg ctctagattt
    17041 cagcaaagaa ttaaactaca ccaaagctat tatggctcgt caaggtgata aagggattac
    17101 agtgactgtt aaaccatttt taaatggctt gcagatggat acgagtggcg gaacatttac
    17161 tttaaaagga acaacgccat ctaaccgtta cgtagatagt gtggcaacta gtgtaactag
    17221 tgaagaagtc acgttttctc ttgatggcac atttatgagt gaagcaggat attataaaca
    17281 ctgctacgta gaatatagaa aagacaatca aattttaaca acgcaagata tcattttttt
    17341 ctcactagga gtgtctgaca tttcgcaagg ccaagccgat gaatacgttt cgcaattgga
    17401 agagttgatt caaaagtata acgaaacttt tgatgctttt atggctgaaa tcgaaggtag
    17461 agtggacagc ttaaataaac agattactga tttaactggt caagctaaaa cactacaaga
    17521 caagttagac gctctgaaag aagaaatttc taaattaggt aacttgcagg tgatgtacag
    17581 taacagcatc ga
//
LOCUS       DAFTHM010000054        16918 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFTHM010000054 DAFTHM010000000
VERSION     DAFTHM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.054"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..1560)
                     /locus_tag="L7C88_001748"
     CDS             complement(<1..1560)
                     /locus_tag="L7C88_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558567.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVT"
     gene            complement(1547..3415)
                     /locus_tag="L7C88_001749"
     CDS             complement(1547..3415)
                     /locus_tag="L7C88_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558568.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVL
                     YYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIK
                     FVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNN
                     DITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPIS
                     LLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAK
                     VIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKY
                     KAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENK
                     IEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            3381..5018
                     /locus_tag="L7C88_001750"
     CDS             3381..5018
                     /locus_tag="L7C88_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558569.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(5163..5903)
                     /gene="truA"
                     /locus_tag="L7C88_001751"
     CDS             complement(5163..5903)
                     /gene="truA"
                     /locus_tag="L7C88_001751"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBP9558570.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(6094..6729)
                     /locus_tag="L7C88_001752"
     CDS             complement(6094..6729)
                     /locus_tag="L7C88_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBP9558571.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIARLSILHLKQ"
     gene            complement(6876..8117)
                     /gene="sstT"
                     /locus_tag="L7C88_001753"
     CDS             complement(6876..8117)
                     /gene="sstT"
                     /locus_tag="L7C88_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBP9558572.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            8315..9313
                     /locus_tag="L7C88_001754"
     CDS             8315..9313
                     /locus_tag="L7C88_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558573.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            9326..11344
                     /locus_tag="L7C88_001755"
     CDS             9326..11344
                     /locus_tag="L7C88_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBP9558574.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(11404..12120)
                     /locus_tag="L7C88_001756"
     CDS             complement(11404..12120)
                     /locus_tag="L7C88_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBP9558575.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(12347..12889)
                     /locus_tag="L7C88_001757"
     CDS             complement(12347..12889)
                     /locus_tag="L7C88_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBP9558576.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(12894..13121)
                     /locus_tag="L7C88_001758"
     CDS             complement(12894..13121)
                     /locus_tag="L7C88_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBP9558577.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(13200..15080)
                     /locus_tag="L7C88_001759"
     CDS             complement(13200..15080)
                     /locus_tag="L7C88_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBP9558578.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(15269..15883)
                     /locus_tag="L7C88_001760"
     CDS             complement(15269..15883)
                     /locus_tag="L7C88_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9558579.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            16025..16585
                     /locus_tag="L7C88_001761"
     CDS             16025..16585
                     /locus_tag="L7C88_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBP9558580.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
BASE COUNT         5401 a         3190 c         2628 g         5699 t
ORIGIN      
        1 cgttactgta taacttgtgc ttactttaat atcagcaact cctttgactc cgcttatttg
       61 taccaatcca ttagcattca cctgctcctt tacaggttga tgatttattt ctacattcgt
      121 tcctaaataa gcatatacag gaagtgtgat tacttggctc ttctcattag ttactctata
      181 tatgatagaa ctaccagttg ttttataagg aaggtttacc cattgactgc caatctttgc
      241 ttcgtgtttt attatatgct ccttattctc caatgaagcg ataggagaat aatcatataa
      301 aaaataatcc attcctttag tggtatacgc ctctactgtt tctttgttta caacaatatg
      361 tcccggctga gaaattattt tttgattgaa atttttttta ctagaaacag ttaaagtgat
      421 taataacaaa acagtcataa ataaataaaa tagttctctt gtcttattgt atcttctatt
      481 tttgaaaaat atcatcgtta atatcagaga agagaatatt atttgcaagc ttaagatccg
      541 ccaaggaaat tgtaacaatt tggctggcgt attttgcaga agataccatg gcaccaaact
      601 agttgtagct agccaagtca aacacgtacc ataataaatc tttttttcta tgtttgttaa
      661 ttttttaaat aaaatcaggg gaatacataa agataacaga ccaactagtc ccattgagta
      721 agtagttaag tcgttgttca tagcttcagt cagactatcg aacacattag atgcatgagc
      781 atataaattt gtcacgctag gtttgttgat tttttggtag agcatttgtt caaacatcgg
      841 ataccaaaaa gcactcgtca gaaccaatgt cattcctgcc gcactaaata attttttaaa
      901 tatagcaata aaatctgcat tcttgaaacc tttagaaacc aaacgaataa aaataaaaat
      961 gataattaat gctgtactca ttaatgttga tagtacatgg ctgtacacta gcaaactcat
     1021 actcaatgct agctttacag acggatactt ttcttctttt ccagagatga tttgataagc
     1081 ataaaataat acagggataa caagtgttat tgcgatagct tcggcaattg cggaacgata
     1141 gtagatgtct actgtccgat aagcagagaa aatatagaga caactaaata aaaatgccgc
     1201 ttttttttgt tttaaaaacc gctcgccata atgataagct acgagtgttg tacacaagtt
     1261 caataaccaa acgtaaataa tatagcttac aatcaaattt tttgtcatcc aatataacat
     1321 tacagctgga aaaaaagtca gaaagggata aaaataattt acaccatatc cagtataatt
     1381 gaatgtctca taattaatcg gactggtaaa aatagtcgat aaccccttga ttcgagataa
     1441 gtgaaaagaa agatctccag tggtataaat actctgtgta tttttgaaaa agatgaaaga
     1501 atatatacta ctaactataa ttaatccact caatattact acttttttat ttattttcat
     1561 tcttcttgtt tatctccttt ttagtcacat atcgagaatc tttcaactta ttaggtgcaa
     1621 atcgtttaaa acttgaatac accactaaac aataagtcag aatactgatc cataaagcca
     1681 tgagagcagt tggagtatat tttgttgtaa tttctatctt attttctcca gcatttacat
     1741 ccacattcac taagccatgt tttttataag agtcatttac gactttaccg tttactttta
     1801 cctgtgtacc taaataagca tatactggta ctgtcacttt ttgctttttg ttgcttgcca
     1861 ctgtgtaagt aatgttatta tctgcagctt tatacttccc tttttcccac gattctccta
     1921 cttttacttc atgtttttct aagtgaggcc tttcttttat cgcttctgtt ggggcgtaat
     1981 cgtataatcc tcccatatct gatgttgtat aacgtgggag tgtttcttca ttgataacaa
     2041 tatgaccgtg ttttgattgg ataacttttg cgtaattttc ttttgctgct atagacgtga
     2101 cgagtagaaa caccacagta gcgccaatga ttaaccatga atatttttta ttcatagtct
     2161 ttttcataaa aacaagcgtt atgatcattg aagaaaaaaa gatttggata cctaagatac
     2221 gccaaggaaa ctggagtaag cttatcggtg ttttttgaaa caaaaaccat ggaaataaat
     2281 tagttacgca tacccatgta gaaactacgc caacatagat gattttttct tttttctcca
     2341 tttctttcag tatgaataaa ggaaaaatca acgcaaccaa tcctaataac cccatagtgt
     2401 atgttgtaat atcgttattt aacgcttgaa tgatactatc tgaaatagaa agtgcttcta
     2461 gctgcaaatc tgttttgaag ggactgtgta tttcttgata attcatctgc tgcaacatag
     2521 gataccaaaa atagctagtt aatgcacaag tcaaaaaaac agcctttact aaattcacga
     2581 ccacaaattt tatatcgttt tttatttgct tgcttaaaaa caaacgaact ataatcatac
     2641 aagcaatcaa tgcactacac aatagtgtag ttaagacatg agtatacaca agtagactta
     2701 tactgacaga taaagcgatg actttttttt ctctattgaa tatcaatcca taagcataat
     2761 ataaaacagc tgggataatc gtaagagcga ttgcttctgc aattgcggat cgataataga
     2821 tatcaactgt tcgataagtt gcaaaagtat ataaacaact aaataaaaaa gcagcatcta
     2881 tctttttaaa aaacttttct ccataataaa aactaatcag aatcgtacaa atatttaata
     2941 accaaatata tagaacataa cttaatatta agttatttga aattccataa aaaacgactg
     3001 caggaattat tgtaagaaaa ggataaaaat agttcagtcc atctccataa ttgttaaatg
     3061 ttgtatagtt gattggccct tcaaaaatag aagataaccc tttgattcgt gaaagatgaa
     3121 aagataaatc acctgttgta taaatttctt gagcatttct cataaaattt actgaatata
     3181 aagtactaag taagataaga actactaaaa gaaatgcttt tttacttatt ttcatagatt
     3241 tgttgttctc cttttttaat tctattttca gtatactaga attgtctttt tttaataagt
     3301 tttgcgttaa atttttcata gcactagtat gatatactag aaaagaatca atttttatta
     3361 cttttaaata ggagaaaaaa atgaaaaaaa acaaaaacca aataatagat atcattttta
     3421 tgttatttct aagttttgct tacgtcatcc ctctattcat gtctaaggga atctatcata
     3481 gtgtcaatca ggatacttac tttcatttat ctcgaatcat aggactagat aatgtatgga
     3541 gttctccagt aaacttcaat aacttcgatc atcatggaac aatgatgaat attttttatc
     3601 catggcttac tctttatcca gcttttttat tttataaaat gatgggaaat cttgttttaa
     3661 gttataatat ctactatttt tttatcactt ttttaacaat ggtcgtttct tatttttcta
     3721 tgaaacaaat aaaaaacaat cgttatattt cgctgttatt ttcgattatt tatacatttt
     3781 ccgcctatcg tgccattgac atattccatc gtgcttcatt gggagaagct gtcgctttaa
     3841 catttttgcc tttgatacta atggggtgtt acgaaattta tattagagat taccaaaaat
     3901 ggtactggtt gtctattggc atgacgctag tagtgtatac tcatttactt tctgtcgcta
     3961 tggtttctgt atttattgga ggaacgttgt ttctttcttt ttatttttgg gaccaaaaaa
     4021 tcgctagact cttaagtctt ttaaaagcta ccgtcctcac ctttttttta agtgcgggat
     4081 tcttaattcc ttttattcaa caatctagag cacaagaatt gaaagtccca ctgggaaaag
     4141 aattaagtgg tatggctcct agtgatatgc tgacacatat tttaaataat aactataaca
     4201 actatactat tggattattc ttatttctcg gattgattgg tgcttttatt tttataaaaa
     4261 aattaactgc tgatgattta tttattttct ttcttggtgt atttgttctt ttttgttcaa
     4321 ccaatttatt tccttggcaa ctttttaacc atacaccagt taagagtcta caatttgtct
     4381 ggcggttaaa tggtttttct tctttattta tagcctatac gatgagtata gtgatctatt
     4441 atattttttc tactaaaaat aattcatgga aaataatggt ctttacgttt cttgcactaa
     4501 tattgcatct ctcaggagta agcaattcta tccatgctaa caaagattca ttaacactta
     4561 tagcacctga agacgctgtt gctatagctg aaaattacaa tcatactgat tatgcaaaca
     4621 aagagtcaat ctatcatcct gatatgatta ataatgatca atatttacta ggtaaccagg
     4681 aaataaatcc aacaactcat tttatgagta acaaacttac aattgaatta gataattcga
     4741 ataataaaaa tactgtcttg acgacaccta tttatcgtta taaagggcaa gtggcttcta
     4801 ttaatggcaa actagtacaa acaaaattat ctaagtttgg cacaactgaa ttaactattc
     4861 ctccaggtat aaataaagtc gttattactt atcagtacac aaaactagca attgcttcaa
     4921 gatatttatc tatcgttact ttgattttat ttttacttta tcgatttact ttttctaaac
     4981 aaaaacaacc gagaagagaa gtacaacatt ctcactagat ttttatttaa gaaagacttt
     5041 ttagctgtac acataaacag gctaaaaagt ctttttttat atttctttaa tttgcttcat
     5101 acattattta acatcgatat ttatactgtg aaacatgcgt ttcatccatt atcaaagtat
     5161 ttttatcgat aataaacttc atccaaaaac agaccttgtg cagggacggt ttctcctgca
     5221 tgttgccgca ctttgctttc aaatatttca tcgattgttt ctatcggcat ggcacctgtg
     5281 ccgatttcta gtaatgtccc catgataatc cgcaccattt tatataagaa tccgtctccg
     5341 acaaaagtaa aatgaagcat ttctcccttt cgttcgatag ataattcatc aatcgtacgc
     5401 actgtggatt tttttgattt tttcaatgca gaaaaaccaa tgaaatcatg tgtacccact
     5461 aatttttcgc aagctgcatt cagcttgtcc atatccaact cttgagggaa ataaaagctg
     5521 tggtttcgct caaatgctga aggaatcacg ttgttccaaa cataatagct gtattttttg
     5581 cccaccgcat tatatcttga atggaagcgc tcaggcattt cttcgattct tttgatgaca
     5641 atatcccgcg gaaggtaacg attcataaag tcgatcattt ctgccagtcc aatttctgtg
     5701 tttgttttaa aatttgctac ttgtcctcgc gcatgggtgc cagcatctgt tcttcctgat
     5761 ccaataattt ctatctcttc atttgtcatc tgatgcaata ctttttcgat ttttccttga
     5821 atggttttat cgtcatctcc aagtctttgc catcctgaat atctttttcc gtcatattcg
     5881 attgtcaact tgatgtttct catattttag tggctcctct gtcttccatt tggtcttctc
     5941 tctacctttt taagattgta gcacaaaata tagctccttg cttctctaag acagaagcta
     6001 tacaagaaaa ctgtggaaat atatatttca gaaaaacaaa aaacagccac cggatgaagt
     6061 atccgctgac tgttcaattt gacggctcaa gttttactgt ttgagatgca agatactcaa
     6121 cctggcaatg ggcacataat taaagaaaaa actgattctt tggcaaaaac ctattttatt
     6181 cagtaatggc caagaattta tagaaggaat tcttgccagt ccataaatcg ccgcaaaaag
     6241 caaactgatc acagacagtc caaggtataa gtggcttacg tccatttgcc cattttttcg
     6301 atagatcaag aaaagaagaa ctggaaacaa taaaaaacca ctgtaaccta aacctgatcc
     6361 gatattatgg acccatgtcg agacattcca cgaagattca tgggtattga tactgaacaa
     6421 acctgtaaag atacaatcac ctataccata gaacgcgatg gctgctgtaa ctagggtagc
     6481 taacacacga gatgtactaa caaatgcagc atacaatgca ggcaatgaca ggatgaaaaa
     6541 gatccctgaa accacagacc aaataagaaa cgcttttctt acaggactgg aaacctctcc
     6601 aaatacactg atcacgctct tcatttgatc taattcagga taatacaatc ctaatacgta
     6661 cggagtcaaa aaatcactca gcacgcctaa taataaaaag aaaaaaccaa atttacgtaa
     6721 aaaatccatg atacgcctcc aataacaatt acctatgctt ttaattgtta ttataaacga
     6781 ctttatcttg atttaacaga aacctctatt tacacgaaca tctatataac tcattaaaaa
     6841 ctcgaatcat tttaaaaata ctaaatatct aacgttcaac gttcacttaa tccatctaaa
     6901 caatctttca atttgatttt ttccccactt cttttacgcg cgcctagctc tcctattgca
     6961 gtaaacaaca gatcacttga cgaatttaag gcagtttcca ttgaatcctg gataacaccg
     7021 ataataaatc caataccgac gatttgcatc gcgacatcat tagagatacc aaacaaacta
     7081 catgctaatg gaatcaataa cagtgaaccg cccgcaacac ctgaagctcc acaagcagct
     7141 aaagcagaca aaatacataa aaggactttc aaaacaaaag gtgcttcaat ccctaaagaa
     7201 tgtacagcag tcaacgtcat caaggaaatg gtaatcgcgg caccgcccat attgatcgta
     7261 gcacctaacg ggatcgatat ggaataagac tcttttgtca atttcaatct ttcagccaac
     7321 atcatgttta tcgggatatt tgcggcagaa cttcgggtaa agaaagcggg aagtgcgctt
     7381 tctttcaaac aaaagaaaat caatggatag ggattttctt taataaacaa aaacgtgagg
     7441 aatgggtaca caactaatgc gacaaacagc atcgtaccga tcaaaacaag taaaagctgc
     7501 agatactctg ccaatccagc gattccagtc gtagcaattg attgataaac caatcctaaa
     7561 atccctatcg gagcaaatgc aataatcact tgtacgactt gtgacaacgc tatagatatc
     7621 tgatccacca actcttttgt cgattctgaa cgtgctcgaa aagctagtcc caacaataca
     7681 gcccagaata agacgccaag gtaattcgca tcaataagag attgaacagg attttgtgtg
     7741 acattcgtca acatagtaga taaaacactt tccaaacttt gcggtgcttt ttcagatact
     7801 gtttcttgta aagtaatagg aacagtaaaa attgaactta caataactgc tacaagtgca
     7861 gaaagcaatg ttcccactaa atataagatc aaaataggct tcacgaatgt cttattccca
     7921 attttatgct tggcaattga cgccatcgtc aagaaaaaaa ccagaatagg tgcgattgcc
     7981 ttcaagcaac tgacaaacaa cgttcccaat attgaaataa atgtccatgt ggggaaaaag
     8041 ataccaaaca atattccgac taaaatacca acaacaatac gttgaactaa cgacatatcc
     8101 aaaaacttct ctaacaaatg accacccttt cacaatttta acaatcattg tatcatttta
     8161 tgcaaagaaa ctaaaggtat aattttctaa aaattctaac aatacaaaca accatttctt
     8221 gctaattttg tactttttct gtctacacgt tgttttttga gatattctaa gttaggatgt
     8281 tattaatggg caacttatca ggaaacgttt tcttatgttt ttgtccaatt tttttgtgag
     8341 gtgtttattc ttgaaaaaaa taaagaagga gagttatggc ttcctgacaa tctttgtcgc
     8401 ttgtataatg atggttttac agcgtatatt gatttcagca gtcactattc ctacatatgc
     8461 aacaaaccct ggtcgattct acatctatac atttttacaa acttccgttg ttattggtgc
     8521 aaatttgatc ccactttaca tgggttacca atatcaaaaa atcgcccgtt taaaagtttt
     8581 acattattta agtcgttttg cctttatatt cctaatagcc acactagttt gcaatatctt
     8641 tttttacgta caagctggca gcttgaatat tcgtgattat tggcttatcc taacacctat
     8701 cagtcagaat tactttactt atgctgtttc ttgtactttg cttttttgta gtattcctta
     8761 tacagttgga tttttaaata aattatcgaa aacaacaatt aaatatctac tattattttt
     8821 aacaattgga ttagttggct gctctactct atttaataaa gacccgtttg cattacagaa
     8881 tggacagagt attttatgga ttttttattt atttttaatg ggttatggtt tgaaagaatg
     8941 gaactggaaa gaaaaggtcc gctataagct tcctcaagta tttatcagct tgattgtttt
     9001 attcggtttg attattttga tgacacaaat ttcactcatc atcagaggaa atacagatac
     9061 agcgctgagg ttttctaaac catattctct cttcgcaatg tattatactt tctcttcgtt
     9121 tttattttta gaaatgctat ctgataaatt aggtataaaa ggaagaggaa attttcttgc
     9181 tgtatttttg attgtcactc aagttatatg taatttccct ttagtttctt atcgcgtatc
     9241 tacatttatg aaacgtgaat ttccaaactc agggaaggca tggctgataa atatcgggca
     9301 gttttttatt tgatatttat tagcagtgtc cctcctagtt atctttttat tttatataca
     9361 aaaaatccgt ttcattcatc gtttcatcga atacttcgct tttgattcga ttgaacaatt
     9421 aactcagcgt tggaaaaaaa gaattcattg gctttttgtt cataaaagtt attttttagt
     9481 tgcagcattt ttttactgct ttaccttcgt gcagattttc gttttagaac caaaagaagg
     9541 ttggaaagaa actatccagg ttgccttaaa aatatttact cagcgacaag cacccatgat
     9601 cctgacaatc atcattatta tgggattttt cttcttacta ttgttgattt ccaatcgttt
     9661 ttggtacgcc ttgactgcta ccttgatcat taacttactg ctcactattt cgacagtaat
     9721 caaaatggaa atgcgggaag agcctgtctt tccttcagat ttaaaaatgc tgaccggatt
     9781 gtcagaacta ttatcgatgg ttagcccagt cttattaatc gtgggcggat tgatccttct
     9841 cctattattg attactagta ttattgtaca acgtagacta caaaaacagt attccttgaa
     9901 gattcattgg aaacgtcgat ttatcagtat cgctgtatta ttaggatgtt tttcgggtgt
     9961 ctttttcatt aatcacaaaa attcgccttc tttcttgctg tttaatttat ttaaagtaaa
    10021 caagactttc tttaaccagc aaggcgccgt aaaagataac ggaccagtca ttcaattcct
    10081 aaacaatatc gacattaaaa tcatggaaga acctgctggc tattcgaaag aaaaaattaa
    10141 tggaataatg aaaaagtaca acacaaaggc agatgaaatc aaccaaacaa gaagtgactg
    10201 gttaaacaat cagacgatcg ttctcaattt aagtgaaagc ttcagtgatc ctgcacgtgt
    10261 ccctaatctg acagtaccta cagaccctat tccttacatc aaaagcatta taacagaagg
    10321 aacaggagga ttgatgttat ccgtcggtta tggtggcgga acagctaaca tggaatggga
    10381 aggactgaca ggcttgagta tcagtaacct gtctgcttcg ttagttacac cttataccca
    10441 gctagtggag cgtcagaaaa taagtccaaa tattaccgat ctattcgatg aaaaaatagc
    10501 catccatcct tttacagctg ctctttatcg cagaaaacaa gtgtttgata aatttggttt
    10561 tgacaggttc tattatttag acagtccgga taaattaact tatacggata aaatagaaca
    10621 aagcccacgc atatcggatg attcagcata caaagaaacc ttgaaagctt tacaaagcaa
    10681 tacggaaacg tcacaattca tccaattatc cactatgcaa aaccatatgc cttatgatga
    10741 ttactatagt gaattgaact acactgctga aggaactgct gtcattccta atagaagaaa
    10801 agaattacaa acttatatgc aaggccttca ctataccgat acagcagtaa aaaaattcat
    10861 ccaagaaatc gacaaaatcg ataaaccgat tacctttgtt ttttatggtg accatttacc
    10921 cgcaatctat agtgggaatg attcgaaaaa atatggatta gaacagcacc agacagatta
    10981 tttcatttat aacaacaagt atagtcgtga acaagcagct acgttaaata aagaagttgt
    11041 tgctcctaat aactttggtg ctatggctct tgagcatgcg aatatcaaag taactcctta
    11101 ctatgcgttg ttgacagaag tatctaatca tctacctgca ttaacaattg atcctacaga
    11161 aagcttgtct aatcgtttta atggaaaaca ggtctttgtt acagaggata gtcaaattat
    11221 ccaagaaaaa aatttaactg agaaacaaaa agaaattcta gaagattatc gtctgataca
    11281 atatgatctt gttgcaggta accagtacag tgcaacatgg gcgacacaaa aaataaaaga
    11341 ctaacaaata aactgagcaa ggggttgtga taaaagacat gtcacaaccc cttgtttatc
    11401 tcattaattt gcttgtccat aaacgatttg attaaagcca tttttcaatt cattattcgc
    11461 tgtctcgttg aagtaaagat aattatcggg attcccctga ttttgttgtg tcaccaatac
    11521 ttttggctga ttttgctgaa acccgaatag atagacgtgc tttttcagat atggttctgt
    11581 ctctgcatcg gaatagacgg ctgtgatttg atagtctgct tgacctgtcc cactttctga
    11641 ccattctgca gaaacaggca ctccaccaat agccatcttc cactccccgt tcaaaatagc
    11701 ttgagggact ttaagaccat ataagtccac actcatttga ttcgtataac ttttgtattg
    11761 ttgtcccatt gtttggcccc atttggtcat aaatgcctct aattgtgcgg atttgtctgc
    11821 attccacagt gtttgttcaa cttgttcgct gctttctgaa gaggaagatg aagcctctac
    11881 agaagaactt gaagtagatg tttgagttgt ttcagtcgtt ttggaagact ctgacgaagt
    11941 agaggtatct gctgtttctg tacttgctgc agttgacttg ctctctgtgc tagttgttgt
    12001 agtagttgca actgttgctt tcgctgtttc ttttgttgat tcttttttcg attcattccc
    12061 gttggtacaa ccagctaaca aaaaagctag accaattgtt actaaaatcc tttttttcaa
    12121 ttaaaaaact cctttcgatt actcccactt ctttattcta tcaaataagc aatgtgattt
    12181 tattgatttt tcgtattttc tcatcaatct ttcaaatctt ctaaaaactg agaagcaccc
    12241 gctgatgttg tctgtaatac atcagcgggt gcttctttta ttttaatctt cgtgattttc
    12301 caatttacct cacgctttat atttgtattt gaagaaacat agacttttag tcatcatcgt
    12361 cttcctcatc caaatcttgt cggacagttt ttccttggag tctttgtact tggtagatga
    12421 tttctttatt gaaacttaaa agttcaacaa gcaattgttg caagccatat ttttcttctt
    12481 tttcagctaa tttgattgcc cgtgtgataa agacattttg gaaatcaaaa tcttttgcaa
    12541 agttttccaa cattgttgag gctggtaaat atttgttttg accatgttcg taaatttttc
    12601 cataacgcat gacttcttct aaagtagacg gaacgatttc attttcaatc actaactcat
    12661 gagagatttt attgaaccat ctcgcttctt gatcagcata ttctgaaaaa agggtactta
    12721 attcttgcga agatgtaccc aaaacataca attgtgcttg gatcaatttc atttcttcta
    12781 atttaaaatt tgctaataca tgccccacca tggcgccagc agttggttta tgatggtcga
    12841 tatctgcttg ttttgtttct tgaacaaatt tttcttccac tatattcatt gatttacgcc
    12901 tcttttactt ttgctgattg gacttcataa cctaattttt ccacaactgc agctaattgt
    12961 tcagggtgga cttcatctgg atcaaagttt gctttgattt tgctcgcatt aaacaaaact
    13021 ttcgtattgc ttaccccagg ctgttgagaa accgcatgtt cgattttttg catacagctt
    13081 ggacaagcta gtgtatctaa ttgcataata atttttttca tcgtagttct tccttccttt
    13141 ttcttgatag tcttattcta gattacagct tccataaaaa aattgattct tatcaagttt
    13201 tacgattttt cttctttgct ttcgtgtcca aaatacaata aacgcatcgc gttaaagata
    13261 acgatcaaga tactagcttc gtgaacgaac atcccactag ccatgtaaat aaacccggca
    13321 aataagccgt tgagtaaaaa taagacgaca ccaatggcaa tcactacatt ttcacgggta
    13381 tttaaaacag ttttcttagc caagcggtag gcatgaacca acgattcaaa attagattgc
    13441 atcaagacaa cgtcactcgt ttcgatagca acatccgttc ctgatcccat agcaatcccg
    13501 atatcagccg cagccaaaga gggagaatca ttgattccat ctccaataaa agcaacgcgc
    13561 aatccttgtt cttggtattt tttcacaaat tgaacctttt cgtctggtaa taattcagca
    13621 tggacttcat caatgcctaa catatcagct acataatcag cagtcatctg attatcacct
    13681 gtcagcatca ctaactgttt tgctcctgct tgtttcaact tagctaattg ttcagcgact
    13741 tctggtcgaa tcacatctga cacacctatg atttgagtga tttttttgtc gattgctaca
    13801 ataatgaccg agctgcctgt ttgttgtaat tgatgtaaat cttgtacttg ctttggtgtg
    13861 agagaaagtt tgtgagcggc aatcaatttg gtgttgcccg cacaaactgt atgaccatca
    13921 atctcagctg tgattccttg tcccttgatt gtctgattat ctttgactgc taattgttga
    13981 aaatcaatgt ctttctcctg agcataatgg atcacggcgc gccccagagg atgatcggat
    14041 aacgtttcta atcgagccac taaagctaag ctgtcccctt catcctctgt atagttcttg
    14101 atagtggata cagcagtagt tcctttggtc aatgtaccag ttttatcaaa gacaaaagta
    14161 tcgattttgg aaaaagtatc cattgcttca ccgcctttga ctaagatgcc ccgtttcgct
    14221 ccattaccga ttcctgctac attcgaaaca ggcgcaccaa tgactaaagc gccaggacaa
    14281 ccaagaacca aaacagtgat tgctaaacga aaatcacgac taatcagacc aacaaccaac
    14341 gcaataagta aaacggttgg agtataatac tgagaaaatc gatcaatgaa tttttccgca
    14401 tgggatttgg tatcttgtgc ttcttctact aattcgataa ttttggcaaa ggtcgtatca
    14461 tctccgacct tagttgcttc aatcgtcacg tagccatctg ctaaaatcgt tccagagaag
    14521 acttcatctc cactgatttt gacgacttgt cgtgattcac cagtcactgc ggcttcatcc
    14581 gcataccctt tcccgtcaat gactcgtccg tccacaggaa tagctccacc agtttttact
    14641 aagacgatat cgccttcttc cacgtcatcg atttccactt cttcagtcgt tccatcttct
    14701 tggacaacac tagcagtaga tggggccatc tcggtcaaag ccttgattga ctcccgcgtt
    14761 ttggtcaatg ttttttgttc cagatagcta ccaaacaaaa acaagaatgt aacgatagct
    14821 gactccttgt attctccgat cataaaggca ccaagcacag caatagtaac gagtaaatca
    14881 attgagataa ctttgacttt cactgcctga tacgcatgga tcataatagg tatgaccgca
    14941 ataatagaag ctatggctag agcaatgtta tagaacaaga caaaaccagt aaattttccg
    15001 ataaaaccaa aaataatcaa cacagctgat aaggcggtga tatgatttcg atgctcttgg
    15061 atccactttt gtaatttcat ctttctccct cttttccttt cattcttacg agactaagta
    15121 tagatactta tccatcataa aaaattgacc actatcaagt ttagtcaaaa aggcggtttt
    15181 cttttggtag aatacactac aaaaaatagt tagcaagaag actcactaaa agtgatcttg
    15241 ccaactattg tcgtttctat cgaaattttc attgaatgat tttcctgtac agcatacatc
    15301 ggagatctat ttctttatct aagattttta tcttgctaat tttttccttt agtctttcaa
    15361 atccacgtcg ttcatagaat tgatacgtac agccactatc tgtaaaaagg aatatttctt
    15421 ttcctttctc tcttttttca aattctgtta gcaacttggt accgatgcct tttgttttca
    15481 aatcaggatt tgcagctaaa aaaatgatct ctccatctgg cgaatgcttc tttaaatatg
    15541 ctgcaagcat ttgttcattt gctgtctcgt aagctccttt actttcttta gcaaatatat
    15601 tttgtaaaaa atcgaatatc ttaacatata tttgctgtcc aaaagaacga tgtttctttt
    15661 tttctccttt tatctccgcc agcaaaacac ctgccaactc gtcctctgca tacaaagcaa
    15721 gaatttgagt tgctcgattc aactccatat acaaaaaata tcttccgtaa agattcagca
    15781 gaagttcatt ttccatatat ctctcaaagt tcattccttc aacagcaaaa tagatagctt
    15841 ttttgtaatc tttcttttct aagggtttaa aagttagttt catcatttcg cctcctcaac
    15901 ttcaatgatt gtgttatact tacattataa tagacacagt gtctactatc tataatcaat
    15961 catctataag tttgtcgatt aagcgacagc tttgctttga tatgtcggat aaggagatag
    16021 gtaaatgaaa aagacagata gacgcgtcaa aaaaacagaa aaagctttgg ctgaaacact
    16081 atccacatta ttagtaaata aaaagattca agcaatcact atacgcgaac taacagaaac
    16141 ggcagatgta catcgttcga ctttttatac acattataag gatatctatg atctatatga
    16201 tcaattagaa agcaactttt ttcgggatct aaatgaaatt ctctcttatg atccagccca
    16261 tagctatgag gaactataca ctcgcttgat tgactatgtt tacgcaaata cttttttata
    16321 tcgcttattt atcctcaacc atggtgatat ttcgtttcag aagaaagtta aacaagttat
    16381 tgaagaaaac tatctgaaca tatggctata tgaagacaag aaaacgatta tcacagaaga
    16441 aatgagattc tttactacgt accacgtcca aggttgtcta tccgttctca atcggtgggt
    16501 agaaagcaat tacaagtact ccaaaaaaga attattagaa ctcttacaga aactgaatga
    16561 tcacatagag aaaatcatgc cttgaataaa aacatactaa gcttagttaa gaagaaccgt
    16621 aaccttctcg tataacaact gaatcttatt tagccaaatt gtttactgaa gattttttga
    16681 gtaaaatttc tataattcct acttattgaa aagtagtttg tagtgctgct tctccctctc
    16741 taagtgatat atcttgttgt accaatcaaa ttcacctcat cattaataaa ttacttttag
    16801 gctaatttat tacaacttat aggttgaagc tgtaaccaat ttatagtcat attatatttt
    16861 tatcatccag tttattgaat tcttctcgtt tacctcaatt cattttcaag gggaatca
//
LOCUS       DAFTHM010000055        16768 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFTHM010000055 DAFTHM010000000
VERSION     DAFTHM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.055"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            245..505
                     /locus_tag="L7C88_001762"
     CDS             245..505
                     /locus_tag="L7C88_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558581.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(867..1106)
                     /locus_tag="L7C88_001763"
     CDS             complement(867..1106)
                     /locus_tag="L7C88_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558582.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            1392..1706
                     /locus_tag="L7C88_001764"
     CDS             1392..1706
                     /locus_tag="L7C88_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558583.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            complement(2140..2506)
                     /gene="ssrA"
                     /locus_tag="L7C88_001765"
     tmRNA           complement(2140..2506)
                     /gene="ssrA"
                     /locus_tag="L7C88_001765"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(2677..3450)
                     /locus_tag="L7C88_001766"
     CDS             complement(2677..3450)
                     /locus_tag="L7C88_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBP9558584.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            3594..3944
                     /locus_tag="L7C88_001767"
     CDS             3594..3944
                     /locus_tag="L7C88_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBP9558585.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            3925..4641
                     /locus_tag="L7C88_001768"
     CDS             3925..4641
                     /locus_tag="L7C88_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9558586.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            4641..6089
                     /locus_tag="L7C88_001769"
     CDS             4641..6089
                     /locus_tag="L7C88_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBP9558587.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(6159..6668)
                     /locus_tag="L7C88_001770"
     CDS             complement(6159..6668)
                     /locus_tag="L7C88_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558588.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(6658..7383)
                     /locus_tag="L7C88_001771"
     CDS             complement(6658..7383)
                     /locus_tag="L7C88_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558589.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(7606..9726)
                     /locus_tag="L7C88_001772"
     CDS             complement(7606..9726)
                     /locus_tag="L7C88_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBP9558590.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            9956..11134
                     /locus_tag="L7C88_001773"
     CDS             9956..11134
                     /locus_tag="L7C88_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBP9558591.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            11150..11908
                     /gene="aroD"
                     /locus_tag="L7C88_001774"
     CDS             11150..11908
                     /gene="aroD"
                     /locus_tag="L7C88_001774"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBP9558592.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            11931..12416
                     /gene="ybaK"
                     /locus_tag="L7C88_001775"
     CDS             11931..12416
                     /gene="ybaK"
                     /locus_tag="L7C88_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBP9558593.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(12487..13740)
                     /locus_tag="L7C88_001776"
     CDS             complement(12487..13740)
                     /locus_tag="L7C88_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBP9558594.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            13858..15207
                     /gene="gdhA"
                     /locus_tag="L7C88_001777"
     CDS             13858..15207
                     /gene="gdhA"
                     /locus_tag="L7C88_001777"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBP9558595.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            15319..16665
                     /locus_tag="L7C88_001778"
     CDS             15319..16665
                     /locus_tag="L7C88_001778"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBP9558596.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
BASE COUNT         5554 a         2894 c         3347 g         4973 t
ORIGIN      
        1 tatgtagatc ttttattagc aaattttaat ataaatgctt tttcatttat taataactaa
       61 aatcgtctat tgaaacaaaa aagaagagaa atcaagaata aaaagagccg gaaagacagt
      121 ggtcatttct gtttttcggt ttttttattt ttttataaaa tcacaagtgt tattgatttt
      181 cacaatcata ttttaatggt attatcattt tgaataatga aaaaacatta aggatggatg
      241 aaatatgaat aacgaaacta tcattttagg aaaaaaatat atttgccaac ctattggctt
      301 gaaacaaaaa gtggttggag aagtaatcag taaattagaa aattgtgttg tgatctgcgt
      361 agacgaatat catgacgtcg atcgcaatga aatattagaa aaatgcggaa aagtagtggc
      421 aaaatatact cacgtttatg agttggaaac aacagaatat ctatataact atagcaacaa
      481 atatgaacat actttagttt cataaagatt taaataaagt gccttcaaaa gcgagaagac
      541 caagcttttg aaggcacttt atttagttgg cagtgattgt tcatgatttt tgatttattc
      601 aaaaggttcg cctagagaat ctgtctctgt aacgaggcct ggtggagaaa ctcgataaaa
      661 acctatactg ccagaactgt cctattttcg gatagacaaa ctagtagttt taaaaagatc
      721 atccgatcca atcatttcaa aaaatgcaaa actgatatca ggatcattta gctcaggctt
      781 gttatcgtaa agcatttgta aaggttgcat ttagttagga gtaaacgcga aactatcatc
      841 attatttgct gaagaagatg aagaagctaa ttcagagttt gtttgaaata aaggagacgt
      901 gctgacagtt tctttaccct gttttttgca gaggtagaaa cttttatatc ggaagtttct
      961 accggagaat ttttctcatt tgtagaaatt gttgaatcga tactattcga aatttgcgta
     1021 tctgaaggta tgttctttga tgcagaagtc ccacaagcag taagtaacaa taaatttgat
     1081 aaactgataa acagaattct tttcattatg tacacactcc ttatagtatc gtttagcata
     1141 cacctatgct cagtattagg caaaatcaat gcaaaactat caagtctttt atagtatcta
     1201 ttagtcttag taatacatat atggagaggg tgatatccca gttcaaacca gatacattgg
     1261 ttaccatctg tattaacgat tatgcctcta aacgcttttt ttatgaaaaa atttataagt
     1321 gaaaacgtag gtatgatatt atctagaggt aatttttttg ggtatttaaa tagttgctag
     1381 gaggatagct tttggatttt tacagtaatt ttatcttaat aatagcaata ttattacttc
     1441 taaatatttg gttttttgat aagagtagaa atgcagggat aggttttaga accaaacgaa
     1501 gtacgtcttc tgaaaaaaag tgggtatatt cacagactat tttttacgga ggggttattt
     1561 caatcagttt actttcttca acactttatt cttttaatgt tatagacgtt tccatgtcaa
     1621 attttatatc tattattgga atccttattt ctgcaattat tacacaacta cttcttgtgt
     1681 ttgaagagaa gtcaaaaaat aattaaagca attatgcctt ttagtacagg aattattact
     1741 tcttacaaat gtatagcgaa tgtgaagcct gctgttttaa ttgttctaga aaaacttttg
     1801 agtgaacaat tattttatgt taggatgaat taatttctct agagtttata attaaaaaac
     1861 ttatttgaag gaacatgctt aaaccataat tgtgtttttc cttccatcag cataaaagtt
     1921 cacctcaaaa agagtgtacg aacaaaagtt ctttttgtaa accttaaaat agattttcct
     1981 gaatacgtat tggggatttc taaatgtttg aatgtttttt tgaatgcaaa atcaatgcaa
     2041 aaaattttgt atttctctac ttttctctcc ttgaccaaaa taaaaaaacg ttgatttaac
     2101 aacgtttttc atacatgttt atctgtctca accatacata tatggagacg gcgggagtcg
     2161 aacccgcgtc caaacacatc gccacttaaa aatctacgtt catagtcaac tcatttaagg
     2221 attcacttta cagcttgccg agtgacaggc attctgtatc gctagtctga tgttctcttt
     2281 ttcaacttac agacggaaag ttgaaacgta tcccactaaa gttaggaccc ttactcgagc
     2341 acatgggcga tgccgagagg atctacgcta actgttttta ggcagctaaa gcgtaagagt
     2401 tgttttcgtt tttagcagtt atatttaact gtaacgtttt tacgtagacg taacctacga
     2461 aacgcaattc aagctcgact gtgcctgtcg aatccgtaac gtccccgtta gctaacaagg
     2521 gttacgtgta tttttcatac aaaattagta tagcatatat tgggataaat tcaataaaaa
     2581 agcgaatcat atcccattat ttatataata actgcccctt tcttaagaaa aaataagcga
     2641 ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa atcagatcaa aatacttcaa
     2701 tgcgtggaca attccgcctt ctgtattttt ctttgtgata aaggtagaaa gttcttttaa
     2761 tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa gcttccaaca aggcaaaatc
     2821 attcggacca tcgccaaatc caaaagtagg aactttttcc agctgaagtt ctttttgcag
     2881 acgtttgaca cctgcccctt ttgagattcc tttcttcact gtatcgatcg agtaaggacc
     2941 attccgataa aaagttagct caggaaaatg ttcgtgatag tattcgtcac ctgattgaga
     3001 taagatcagc aacatattta ctgtgttttc tttaaagcct aaaggatcaa tttccggaac
     3061 atctgaatga atgaagtcgt aagcattgat cattgtttgg ctatgaccgg tacaccagat
     3121 tttctgatcg ttatagtaag aaagttcatg accgttcaac tgtacatgat catacatttt
     3181 ttgacattct tctgaagaaa atgtttgaga atagatttct tcgccgtcta ctcgaatgaa
     3241 agaaccattc atggtgaccg cagaagtaat gcccgcatct tccatgatag agtggatttc
     3301 tgcttctgta cgtcctgtag cgatgacggg gagaacattg ttttctttta atgcgttcat
     3361 agcttttgcc acttcgggtg tgatttttga tttcgcatct agtaatgttc catcaagatc
     3421 aaagaaagtg attgcacgat aatttgacac aaataaaact ccttttttat tggaataagt
     3481 ttatcttaac aaagaatgaa caaaagacaa acctttcgtg aagaattcct gaacatattg
     3541 gttcagtcaa caatttagag tatactataa gaagagaatt taggagggaa agaatgattt
     3601 ttttcagtat tggtatctta ttcttaataa ttggcagtct ttttcggatt ctgccctcaa
     3661 aaggaaatct gcctttttat gggtatcatt cgcctcttgc cgcaaaaaca gacgctcatt
     3721 ggcggctggc tcaaaagaca agcggaaact ggttttttct tatgggctta ctgatggcat
     3781 tgatcggcta ttatttaaag acatctgggc atacgaatta ttttctgatt gaaatgcttc
     3841 tgctagtatt tccaattatg cctattttta ttatgacaga aaagaaatta cagaaatatg
     3901 acctggaaac tggagggaac gataatgaat attttaatga ttgaagataa tcaatctgtt
     3961 tctgaaatga tgcagatgtt tttcttaaat gaaggttggg aagcaacttt caagtatgat
     4021 ggaaaagaag ggctcgatgc ctttttagaa aacccacaac attgggatat gattacacta
     4081 gacctgaatt tgcccacact ggacggtatg ctagtaggaa gagagatccg caaagtttca
     4141 agtactgtgc cgattatcat gctgacagct agagattctg aaagcgatca ggtgatcggc
     4201 ttagagatgg gggcagatga ttatgtcaca aaacctttca gtcctctgac gcttattgct
     4261 cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag caagagaaga agcagcagtt
     4321 tcagatgatc attttgatat cgagactagt catttcaaga tgaatacgaa aacacgagaa
     4381 gcgtatctgg acaaccggcc aattgaagga ctgacgccta aagagttcga tctattgttt
     4441 actttagcaa aaaaaccacg tcaagtattc tctcgggagc agttgcttga attagtctgg
     4501 gattatcagt actttggtga tgaacggaca gtggacgccc atatcaagaa attacgacaa
     4561 aaaatcgaaa aggtcggacc acaagtcatc caaactgttt ggggagtcgg ctacaaattc
     4621 gatgattctg gtgttgccta atgcgttatt tgtatcagca actcttagct ttttgcggaa
     4681 tggtcgcgtt gatcttattg atcgttggag tttcttttac acaactgaca aaacaaacga
     4741 ttgaagaaaa caattaccag caactgtttg gatatgctga atcagttgaa aagacaacgc
     4801 aaacctatgc cgatacgctc ccgcagttta gtcaagatca ggcgtttcaa aatgcattgc
     4861 tgctgacaga gcaagtactg acagaacaaa atgtgaactt tatatttatc gataaaaacg
     4921 aacgtgtcat ttatccgact aatacagctt tactgaattt taccttaaca gctgatcaat
     4981 ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc gaataaaaat attttaggac
     5041 aagcacaggc gacctcttac gcacttgtgc catttaattt gaatcatgaa ttctatggag
     5101 cacttgtagt tagtcaacct gcgcgaaata tcgataacag cgttcgtcca attacactga
     5161 acctgttcaa aggatttatt ttttccagta tcgttgcagt tattgccagc tatgcttttg
     5221 cagcattcca agttaagcgt atcaatcggt taaggaatgc gacgaaagaa gtgacgaatg
     5281 gtaattttga tgtacagctc cccgtacatg acaaagatga atttgatgag ttagcagatg
     5341 atttcaataa aatgacgaat tcattgaaag aatctcaagc agaaattgaa gaacaagaaa
     5401 atcgtcgaag acaatttatg gcagatgctt ctcacgagat gagaacacct cttacgacaa
     5461 tcaacggact tctggaaggg ttagaataca atgcaatccc tgaaaatcag cgagaaaacg
     5521 cgattaaatt gatgaaaaat gaaacagagc gtctgatccg tttggtgaat gaaaacttgg
     5581 attatgaaaa aatccgtacg aatcaaatca gtatggtcat taaaaaattc aatggaacag
     5641 aaacattgaa aaatattgtt gcacagttag aagctaaagc agaagcagca ggagatacat
     5701 tgacattgaa agccgttgat gatattgatg tttacgctga ttatgaccga tttgtccaaa
     5761 tcatggtcaa tattattcaa aacgcgatac agtttactga aaacggccaa atcacgatta
     5821 ctttagaaaa aggctatctt gaaacgatca tcacgattga agatacggga attggaatgt
     5881 ctgaacaaca aatgaaaagt atctgggatc gttattataa agtagatcct tcaagaaaaa
     5941 atacaaaata tggtgaatca ggattaggtt taccaatcgt gcagcaactt gtacgcttgc
     6001 ataaaggaaa attagaagta gaaagcgaac taggaaaagg aacaaaattc gctgttcgtt
     6061 tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg tataaaagat catgaatcga
     6121 tcttctatac cgcttgtttt tactataaaa tgattgattt agcccgcggg ctctaaacga
     6181 tcaatataag gactttgagc aatagtagca tcatgagtaa agagtaagat accttgattt
     6241 tcttcatgag ctaaataaga aagcaagtgg agtagctctt ggatctccaa tacactaagt
     6301 tcatcaaatg tatcttcaat aacaatattg tttcgcttgg aaagcaaggc atgaagtaat
     6361 tgcagcttta ctttttcaaa agacgtcaac tcagctgccg cacaattaag caaggaagga
     6421 gagatatcaa gtttttcttg ataggccaaa cgatcttgtt tgatttcttt ttccggtaca
     6481 tccaacagga catggtcttt aagattcaga taaggaaaca tcggccaatt tttttggatg
     6541 atcgcaaaat tatccagttt tgcaacaaga acctcttttt tcaagtgctc caatatttta
     6601 tgctgttttt cgagaggaca caaaataacg gtcaagtgtt cagcatgaat caaatattca
     6661 ggtttcatta cgtccaggcc tcctactttg caaatgatgg ataaaaaaag tgaaagggaa
     6721 tagactaaga atgagacagc atccactgag cccaataaga gtttgggcaa atcccttaag
     6781 tatatctgtg aaaaaaagat cattttggaa atcgatggta aaaaaagtct gttgatccat
     6841 cggaattgta agtccgctta ccgaagtcaa gatatcacgg atatctggca gttcagtagt
     6901 ctttaagaca agaaaattga tcctttgaag aagcgcttca taaactgact ggaagcttac
     6961 gatccacaat aaaaccaaga tacaacaaag aaagagagga aagaacagct gccagaaaat
     7021 aaaaaggaat aatttggttt tagaaagacc agtcaggcgc caattgatca attcctgctt
     7081 gttttgcctg actgaatagt aaaagaaaaa gataaaaagg aaggcaaata gaaaaaataa
     7141 actgaatatg ccttttatat aaaatcggct agctaattct aaagccggaa gaagctctgt
     7201 agatgcagaa gcgccaataa atgaaagccg atcttggact tgattggcta aagccgattg
     7261 caaatggtaa agagtcaggc atgctatcaa taaaaaagca gaaaagcttg aaaataaaca
     7321 atagagtatt gtctgctttt tgtaataaat taatcgagca gtagcatagc ggattatttt
     7381 catacttttc acctctataa aaagtataga aaatgaatat gaataaagta tgaaattcct
     7441 ttagtgaaat cacgaattaa aaccagaaaa tattttgtaa aaagcaagag gttgtgaaga
     7501 agctgcccta ttctattacc gtagatgcaa gcttttgaac actgtttatt cgaaaagagg
     7561 agcagcgaca ataattttgt cgctgctcct tttaaattta ttttgtcatt cggaagaact
     7621 tgtggtcgtt ccgtgaagtt cttggtacgt ttgcgtttta taaagatcaa cagttgattg
     7681 tccgttgtgt tcactaaaga cactagttga cttgtcacca agagattttt cagcttcttt
     7741 taatttctct aagccattct tgtagtcata atcactggta tcaattgggt ctaatccact
     7801 attcgtatag aaccgaagaa gatcaccatt attgatttgg tcagaaacag ctaactgttt
     7861 atcaactttt tctttcagtg aatcaatttc attctgtact tcctcagtag gttcagtaat
     7921 agcttcacca gtttcgttac tatagatcgt accaccgtag taagtatatt ttggtgtaac
     7981 aaaatcacca tcacggaaag aaacaagctg ttcatgatct ttcgagaata gatcttgtcc
     8041 taactgaata taattttttg tatctacacc tagtaagtga agtaatgtag gcaaggcatc
     8101 aacttgtccg ccgtaagtgt gattgattcc gccctgtgtt tgtccaggga tatggatcat
     8161 ataagggaca cgctgcattt gtgcattgtc gtagtttgtc caagtagaac ttgtttttcc
     8221 aactaattca gctagatttt tatttcttga attcgagaca ccgtaatggt caccgtaaag
     8281 gacgatgact gaattatcat acaagccgct ttctttcaaa taattgaaga attcttgtac
     8341 ggcggtatct aaataattgg ctgtcgcaaa gtaaccgttg atcgtttcat catttgtatt
     8401 ggctaacggg aatcctgctt cgtcattggt gaattttgaa taaggataat ggttagatac
     8461 agcaatgaat tttgaataaa atggttgttg cagacgttcc aagtattgta cggattgttg
     8521 gaaaaatggt ttatcatgca acccgtattg gaacgaattg tcatcattaa catcataata
     8581 agaagaatca aagaaataat catatcctaa attcttgtat gtctcgtttc gattccagaa
     8641 tgtaccagcg ttcccatgga ataccgcact agtgtaacct tgtgtttgac ttaaaatatc
     8701 aggtgcagct tggaaagtat tttttccgcc taattgtgtg aacaaggagc cttgattcaa
     8761 gccaaacaat gaattttcca tcagcgtttc cgcatcgctt gtttttcctg cttttacttg
     8821 atggaaaaag ttgtcaaaac tgaacgtgct gttgctgtgg taaagactat tgatgaaagg
     8881 tgtaacttca tgctggagac cattctcatc tgtcaattta taatcgatca ggaattgctg
     8941 gaagctttct aaatggatat aaatcacatt ttttccttta gcgagcccga acaaatcgtc
     9001 atttggtgct gcataatgtt cttttacata attttctact tctttcatat cattgggact
     9061 tgcttctgcc cgcacttggt ttgtctggta agtttgaaca ccgtcataaa ccatgaaagc
     9121 attcaagcca agatatttga ccaaataatc acgagagaat gttcgagtca gcaattctgg
     9181 acgatcagct tccgccataa aaagatttcc tgagaaaatc ataactgcta atgtagagat
     9241 cgcaaaagcc attcttgctc ggatcgggcg agggtccaac ttgatttttt ttgcaatcag
     9301 cagaacagtc aagataataa aatcgatcca atagatcaca tcatatgggc gaaacagtcg
     9361 aatggcactt tctcccagac cactcgctac tttcccagca cctaaaatcg tgttgatcgt
     9421 aatgaagtcc gtgaattctc gataataagt gacattcgaa aaaacaagca atgtcaaaag
     9481 aaaataaatg accatcatcg tgatataagc aactctaggg cgtctgatat aaagagcaat
     9541 tccaagtaat aacaatgtag ttgcaatagg gttgataaac aagataaagt attgaatgcc
     9601 actttcgatt ccgagatgga aatcaactaa ataggcaaaa atcgttttca accaaagtaa
     9661 aacgactagt aaagaaaaaa atccgagcct cttattcaaa aaggcaggtg tttttataca
     9721 tttcaagata atcttccttt ctgcacttct taatcacaga agtgtcatga aaccatgtta
     9781 cacagctcac ttattctcat ttattttact agtatgacaa tatagtgtca attgaaacca
     9841 gaagtttatg ctgtttcatt aaggttttct ttaagcttca tgaaaaaatg agcagtaaga
     9901 caagtcctat gttttttgtt atacttggga agagaaagct aaagcaggtg aaggaatgaa
     9961 agtaaaagta aaaaaaagag caagcaatcg attgaaaaaa ggatatccac tgatccaaaa
    10021 agaagacctt gctcatcccc aaaaagaaac cacgcaatgg gtggaattag ttgattcgca
    10081 aaaccaattt atcgcaaaag gatatctagg aaagcagaat aagggaatcg gttgggtatt
    10141 gagccagcag aacatcccat ttgatcaatc tttttttgaa gaattttttg tgaagtcaaa
    10201 agaaaaaaga actttctttt tttcagatga ttctactacc gcttttcgta tattcaatgg
    10261 agaaggagac ggaatcggcg gtctgattgt tgattattat gcaggttatg ctgttttttc
    10321 ttggtataac gaaacgttat atgcacatcg tgaattattg attcaagctt ttcgtgaaat
    10381 ctacccggaa atcgtaggag gctatgagaa aattcgattt gaatcagtaa atctgcctga
    10441 gagccagttc atttacggaa aagaggcacc ggaacccttg atcgtaaaag aaaacggagt
    10501 aaaatttgcc gtttatttaa atgaaggatt aatgactggg atctttttag accaaaaaga
    10561 agtacgggga tcattagcag aaggtttcgc ttctgggaaa acagttttga acatgtttag
    10621 ttataccggc gccttttctg ttgctgccgc aatgggaggg gcaatcgaaa caacaagtgt
    10681 cgatctagca aaacgcagtt taaaaaaaac acaggaacag tttgaagtga atggtttgga
    10741 tgtcgatcag caaaaaatca ttgttatgga cgtattcgag tatttcaaat acgccaaaag
    10801 aaaacaattt ttatatgaca tgattgtatt ggatccacca agttttgcca gaaataagaa
    10861 aaaagtcttt cgcgtagcaa aagattatgg ggaactggtc aaggatagtc tggatatttt
    10921 agcagaagac gggatactta ttgcgtctac aaatgctgcg aatgtctcga tagaacaatt
    10981 ccaaacaatg attgaagagg aattccatgc caaaaatgtt tcttttgaac aacttgcttt
    11041 atatcgtctg ccaaaagatt tccagacgac ggataccttt ttagaaggca attatctgaa
    11101 agtgtttgtt tatcaaatta aaaataacca ttagaaggag cgatgcagaa tggtttgggt
    11161 aaagggattg aatataggaa gcggtagacc aaagatttgt gcgcctctta tcggggccgt
    11221 ccgagaggaa gtattacgtg aagcagttct tgcacgtgaa gcaggggccg atttagtcga
    11281 atggcgagtc gatcattatc gtgaagtttt ttcttttgat gaagtagcag aaacattggt
    11341 tcttatccat gagatgcttg atggactgcc gttattattt acgtttcgta ccttagctga
    11401 aggcggagaa caagacatat cgatccgtca gtatcgcgac ctttatgaac atgtgataca
    11461 cacaggatta gtagatatgg tcgatatcga gttgttcaaa gtagaaagtc taggaaaaag
    11521 actgatagag gaaatcaagt ctttaaacat tcctttaatt atcagtagtc atgattttaa
    11581 agaaacacca gcagaccctg tcttgcttta ccgattgaat gttatggaac attttggagc
    11641 cgatatcgga aaactggcag taactcccaa taatgaacga gatgttttgc ggttgatgga
    11701 gttgactaga cgggcaaatg cttttgtctc catgcctatt attacgatgt ccatgggaaa
    11761 tcttggtaaa atttctcgtc tggctggcgg aacgacgggt tccgttatga catttggttc
    11821 cttaagcagc gattctactt ctgctccagg acaattaccg gtcaaagcat tgaagcaaat
    11881 tattcaatta ttaaatgaac cgttgtagaa caagtttgag gtgatatttt ttggcaaaga
    11941 aaaaaatagt aaaaacgaat gcaatccgta tggtcgaaca aaaaaagatt ccctatacag
    12001 agcacgaata tgagtgggac gaaagccacc taagtgcgtc atcggtcgct gaacagcttc
    12061 cagaaagcca atctcgtata tttaaaacac tggttgctgt gggcaatgtg acggggcctc
    12121 ttgttgctgt gataccggga gaagccgaat tgaatctaaa aaaattagca aaagtttcag
    12181 ggaataaaaa agtagaaatg ctccatttaa aagatttgga agcaacgacc ggatacatac
    12241 gtggtggctg ctcgcctata ggtatgaaaa aactatttcc tacttattta gatcaaattg
    12301 cagaaagcta tgaacaaatc attgtctcgg ctggcagaag agggctacag atggagttag
    12361 cacctcaaga tatctgtgca ttaacgagcg gacaatttgc agatataaaa caataaatca
    12421 tacgtataaa agaaagaagg aggccgggat gttgtttgtc cagtctcctt ctttcttttt
    12481 tatacattat gctctttgcc cggcattcat tcctgctaca tgccctgtag cgaaagccgc
    12541 tgtgatatta aagccgccag tataaccatt gacatccagt aattctcccg caaaatacag
    12601 accatcaatg attttactct ccaatgtttt aggataaatt tcctttagag aaacccctcc
    12661 gccagttaca aatgatttct caataggaaa agttttgttg attgatagct taaactcttt
    12721 gcatagttga acaaaatctt gaatttgttt ttgagaggct tgttgtcctg tcagatgatc
    12781 catttcaagc cgctcaagaa agaaaactaa caatcgctca ggcaatatac catgccaagc
    12841 attgaccaag ttctttttgg ttgctttact tttttctgtc aatatatgaa taagctcttg
    12901 tttggtttgt gtagggaaac aatccagaga aagtgtcact ggttctcccg ttttctctaa
    12961 ttctttattg acaaaacttg aacaacgcag tgcagccgga ccagaaatac cgaaatgggt
    13021 gaaaagtaaa tccatcgtat gttcagtcaa tacacgacct tttttattta aaacgcgtaa
    13081 agtgatgtct tgtaaagaaa gcccttgaag tgttttctcc tgaatatacg gttcatccga
    13141 tatcaagggg gactctgtcg cataaagagg cgtcaccgtg tgacccactc gcttcacgat
    13201 cttgtaccca tctccagtag aaccagtaga tggataagtc cgtccaccag ttgttaagat
    13261 aatggcagga gcatggaact cttcgaattc cgtgcgtata ccgtaaattt tatgttcttt
    13321 gtggatcaat ttctctactc gagtagagaa tagaagcgtc acatctagtt ctttcagacg
    13381 attgagcaat gcttcgataa tcgtttttga tttatttgtt acaggaaaca tccgtccatg
    13441 atcctcttct tttaaatgta cgccttgtga ttcaaagaag ttcatgatat cgaaattatt
    13501 ccattgcgca aacgtactat ataaaaactt tccatttcca ggaatatgtg caatcaaatc
    13561 atcaacagga cgattgttcg taacattgca ccgaccacca cctgtcatca gtagtttttt
    13621 tcctgctttt ttgttttttt cgatcaagag tacgcgtgcg ccttgttcag ctgcactgat
    13681 cgctgccatc atcccgcttg ttccagcgcc gactacgatc acatcataca gtttttccat
    13741 tccctcacct caaggaaagt gtagcatatc tgaagaaaga aaacagaaaa aaaatgtttt
    13801 gagccaaaag agaaaatgag ctaaaatgag ggaagataag caaaggagcg tggaacgatg
    13861 acaaacgcaa cagaatatgt tcaagcaatt caagaaaagc tacatcaaaa ggatcaaggg
    13921 caagaagaat ttttacaagc aatcgatgaa ttcatgccca cggttatgtc ttttttggac
    13981 actcatcccg aatatatcga aaagaatatc ttagaacttt taacggaacc agaaagagtt
    14041 attcaatttc gagtgccttg gcaagatgat gaaggaaact ggcgagtaaa tagagggtac
    14101 cgtatccaat acaactcagc tatcggccct tataaaggtg gattgcgctt ccatcctagt
    14161 gtcaatctaa gtatcttgaa atttttggct tttgaacaga ttttcaagaa tagtttaacc
    14221 ggtctgccaa tcggtggagg aaaaggcgga agtgacttcg atcctaaagg aaaatctgat
    14281 aatgagatca tgcgtttttg tcaaagtttc atgctggaat tgtcaaaaca tatcggccca
    14341 tcgattgatg ttcctgcggg agatatcggt gtaggagcta gagaaatcgg ctatttgttc
    14401 ggcgaatata aacgattgaa aaaatatgat actggtgtgt tgacaggtaa acctttggat
    14461 ttttggggaa gtaagatacg tacggaagct actggttatg gattagtgta ttatgtcaaa
    14521 catctattga acgaagaaaa agattcattt aatcaaaaaa cagtttttgt ttccggaagc
    14581 gggaatgtag ccatttatgc aatcgaaaaa gtgcaagagc taggcgggaa agttgttaca
    14641 tgttcagatt ctagcgggta catctatgat ccagaaggaa tagatgtgaa actattgaaa
    14701 gaagtcaaag aaatcaatag acaacgtttg acggaatacg caaaccaacg tccttctgct
    14761 atttatcatg ctggagaatc tgtttggaca ttgaaagaaa aagcggatat cgctttgcca
    14821 tgtgctactc aaaatgaaat agacgaaagc ttggccgaaa tcttagtaga aaatgggatc
    14881 aaaatcgtag cagaaggcgc taatatgcca tgtacagtaa aagctgtttc tgttcttcat
    14941 gaagcaggcg tgtggtattg tccaggaaaa gctgctaatg ctggaggagt agcagtatct
    15001 gctttagaaa tgagtcagaa cgtccagcga ttgacttggg aaagagagca agtggatgag
    15061 cagctggatc aaatcatgga aacgatttac catacgtgtc gccaaacagc agccgagtac
    15121 ggcgacgaaa aaaatctgct tcttggagca aatgttgctg gatttgaaaa agttgccaaa
    15181 gcaatggcag cagaaggttt agtttgaaaa atgaaacttt cttggaaata ttgtcagcat
    15241 tttgtttatt tgcttgaaaa ataataaaaa aaaacgtaaa gtattacctg tagagtaaac
    15301 ctataaggag gagaacaaat ggcacacatt cattttgact attcaaaagt agcaccgttt
    15361 gtcaacgaac aagagttagg gtacatgcaa agccaagtaa cagcagccca caacgaatta
    15421 cgggaaggta ctggcgcagg aagcgacttc cgcggctgga tcgatttacc aacgaactat
    15481 gacaaagaag aatttgcacg tatcaaagaa gcagctaaaa aaatccaatc tgattctgaa
    15541 gtattagttg ttatcggtat cggtggttct tatttaggcg ctcgtgcagc gatcgacttc
    15601 ttgaatcaca cattcttcaa tttattagat agcaacacaa gaaaagcacc acaaatcttc
    15661 tttgccggaa attcaatcag ctcaacatat attgctgact tgatcgaagt aatcggtgat
    15721 cgcgactttt cagtaaacgt tatttcaaaa tctggaacaa ctactgaacc agcgattgcg
    15781 ttccgtgtat tcaaagagct tcttgttaag aaatatggac aagaagaagc aaacaaacgt
    15841 atctacgcta caacagataa agcaaaaggt gcagttaaag tagaagcaga tgcagaaggt
    15901 tgggaaactt tcgtgattcc tgatgacatc ggcggacgtt tctctgtatt aactgctgtt
    15961 ggtttgttac caatcgctgt tagtggtgca gatatcgatg cattgatgca aggtgccgct
    16021 gatgcaagca aagcatactc aagcgacaaa ctagaagaaa acgaagctta ccaatacgca
    16081 gcaatgcgca acattcttta ccgtaaaggc aaagtaactg agttgttgat caactatgaa
    16141 ccaggaatgc aatacttctc agaatggtgg aaacaattgt atggtgaatc tgaaggaaaa
    16201 gaccaaaaag gcatctatcc ttcaagcgca aacttctcaa ctgatttgca ctctttagga
    16261 caattcatcc aagaaggacg tcgcaatatt tttgaaacag ttgtgaaggt tgaaaaacct
    16321 cgtaaatcaa tcacaattcc tgaacaagca gaagatttag acggtctagg ctacttgcaa
    16381 ggaaaagaag tggacttcgt aaatacaaaa gcatttgaag gaacattgct tgctcataca
    16441 gacggtgacg tgcctaactt gctagtcaaa attccagaaa tggatgctta tacattgggt
    16501 tatacaatgt acttctttga aattgctgta ggtatttcag gttacttgaa tggaatcaac
    16561 ccattcgacc aaccaggtgt agaagcttac aagaaaaaca tgttcgcact tctaggcaaa
    16621 ccaggctttg aagatcttgc taaagaattg aacgaacgcc tgtaagataa gggtttttcg
    16681 ctagatttaa ataatcagtg atagaaacat gttcgcttta aaatgaaaac tggtacccat
    16741 ttaggtactc aaacatactg catcgttt
//
LOCUS       DAFTHM010000056        16665 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFTHM010000056 DAFTHM010000000
VERSION     DAFTHM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.056"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(157..864)
                     /locus_tag="L7C88_001779"
     CDS             complement(157..864)
                     /locus_tag="L7C88_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBP9558597.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(943..1281)
                     /locus_tag="L7C88_001780"
     CDS             complement(943..1281)
                     /locus_tag="L7C88_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBP9558598.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(1392..2354)
                     /locus_tag="L7C88_001781"
     CDS             complement(1392..2354)
                     /locus_tag="L7C88_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBP9558599.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(2369..3700)
                     /locus_tag="L7C88_001782"
     CDS             complement(2369..3700)
                     /locus_tag="L7C88_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBP9558600.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(3708..4388)
                     /locus_tag="L7C88_001783"
     CDS             complement(3708..4388)
                     /locus_tag="L7C88_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBP9558601.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(4607..5086)
                     /locus_tag="L7C88_001784"
     CDS             complement(4607..5086)
                     /locus_tag="L7C88_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBP9558602.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(5213..6892)
                     /locus_tag="L7C88_001785"
     CDS             complement(5213..6892)
                     /locus_tag="L7C88_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBP9558603.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            7440..8942
                     /locus_tag="L7C88_001786"
     CDS             7440..8942
                     /locus_tag="L7C88_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9558604.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            8955..9617
                     /locus_tag="L7C88_001787"
     CDS             8955..9617
                     /locus_tag="L7C88_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558605.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(9718..9921)
                     /locus_tag="L7C88_001788"
     CDS             complement(9718..9921)
                     /locus_tag="L7C88_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBP9558606.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(10032..11216)
                     /gene="iadA"
                     /locus_tag="L7C88_001789"
     CDS             complement(10032..11216)
                     /gene="iadA"
                     /locus_tag="L7C88_001789"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBP9558607.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(11373..13112)
                     /gene="yfcC"
                     /locus_tag="L7C88_001790"
     CDS             complement(11373..13112)
                     /gene="yfcC"
                     /locus_tag="L7C88_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBP9558608.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(13885..14499)
                     /locus_tag="L7C88_001791"
     CDS             complement(13885..14499)
                     /locus_tag="L7C88_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBP9558609.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(15105..15482)
                     /locus_tag="L7C88_001792"
     CDS             complement(15105..15482)
                     /locus_tag="L7C88_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558610.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(15782..16663)
                     /gene="galU"
                     /locus_tag="L7C88_001793"
     CDS             complement(15782..16663)
                     /gene="galU"
                     /locus_tag="L7C88_001793"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBP9558611.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         4829 a         3592 c         2846 g         5398 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcccttatt ccaaataaat ggtattcaat cagctaactc tcggtattag
      121 ctcagatcaa agcgctgatt tcacaacttc tttattttaa tctcttcggt tgccgccgaa
      181 caataagatc aagcgcaaca gctgcaggaa tgtcgaaagc gctgctgcaa cataagtcag
      241 tgctgctgca aataatacgt gtcttgccat cggtacttct tcttccgtca gtagtccgcc
      301 ttcactcaaa atttggattg ctcgccgaga cgcgttaaat tcgactggta atgtcaccaa
      361 ttggaaaagt aatgctaaag aaaaagcgaa aatcccgata ttgattaacg tagagttcca
      421 gctaagcaat acacctacca taatcaaggg gaacgaaatc atcgaaccaa agttagctgc
      481 tggaacaagt gctgcacgaa tcttcaatgg gacataaccc gaagcatctt gtaccgcatg
      541 tccgcattca tgagctgcta cacctatcgc agcaactgaa gtagactgtg cagttgcttg
      601 agacaaactc aacatcttat tacctgaatt gtagttatct gtgagatctc cggcaatttg
      661 ttgaacaccg acattattta tctgttgact ttgtaatata tattgtgctg cttgtgtacc
      721 agtcacattg tttttgcttc tcacttgatc gtattttcgg aaagtactat tgacgtacgc
      781 tgacgcaatt ccggaaataa ctaatccaag aatgaccaaa agaaatgtcg gatctaaaaa
      841 accatacatt ccataaccat acattttcgt ttcactcctt ttcgtttact ttattttatc
      901 attagtagta ggaaaagaat gtgaaaagac cttgaatatt ctttaattct ttttcacaaa
      961 ttccgatttc agtttcatcg gtccaaatcc ttctaccttg caatcgatat tatgatcgcc
     1021 ttctactaaa cggatgttct tgacttttgt tccttgttta atggcacctg acgcaccttt
     1081 tactttcaag tctttaatca ctgtcacgct atcgccctct aacagacggt ttccatttgc
     1141 atctaatacc actaatccgt cttctatgac agtttcttgt tcttctttgt tccattcgtt
     1201 cccgcattct gggcaaatca acaagcctcg atcttcatat gtgtactctg agccacattc
     1261 tgggcaattt ggtaatgtca tcttctttct cctttaaaat ctttagtgag cactattgta
     1321 acggaaaaag aagatcttga aaagatacat ttgtgatttt tactacaaaa ggcacgtttt
     1381 cgaacgaagt atcattctgt ttttctgctc ttatacgatt ggcatatatc ttggatctct
     1441 ttatagattt cctctacttc tgctaaatct tttgcattcg caccacttgc taatggatgg
     1501 cctcctccat gatggcgttt agccaattca ttgatgatcg gccccttaga acgtaaacgt
     1561 acgcggtaat accctgaagg ctgctgaaca aaaatccccc aagccagcac ttcgtcaatc
     1621 actccaggaa gtgaaacgat cgaagctgtc tctgaatcat cgattccata tttatcaaga
     1681 atttcttgcg gaaggattat tcttcctgca ccattttcat ccacctggat attttgataa
     1741 agataaccgg aaagtttagc gactttcatc ggcatttgtt caatctctct gttcaaagca
     1801 cttgcatcaa atggataatt tctcaatatc gaagcaatct ctaatgtacg ggacgtcgtg
     1861 gagggataca aaaagcgccc tgtatctccg acgattcctg cataaagtaa ccgtgcagcc
     1921 ttaacgttca tctttaaaga ttcaggaaac atcaaagcaa attctgcaat catctcacta
     1981 cagctacttg cttttgtatt tacccacaca agatctccat aagggtcatc attgggatga
     2041 tggtcgattt tgatcagttt ttctgccaac tgatatcttt gatcactgat tctgggtgaa
     2101 ttagctgtat cagtcacgat gactagcgct ccttggtaga agacatcttc aacttcttgc
     2161 atttctgcta aaaagcgaag cccttcaatc gtttcaccta cttgacgtat ttctttttct
     2221 gggaaacttt cccgtaatag ttcggctaat cctacttgtg atcctaatgc atcaggatca
     2281 gggcgcaaat gcctgtggat aatgatttta tcgtattttt ttattgtatc tactatttct
     2341 tgctgtactg tcatttcact cctgctttct aagaacgttc cattacttga caaacaacga
     2401 ttgctttgga aacgatggtg ttttcaataa acacttcgat atccagttta gcggaacgtc
     2461 tgccgatttc caatacacgt ggacgaatgt ctaattcgct ttccaattgg atcagccgca
     2521 aataatgtag gttcacttgt tcaatcaaga tatttcgttt ttggttcatc accattgttt
     2581 tttgtgcgac atcagaaatg atttcgctaa gtacgccaaa agaaatggtt ccaacgccat
     2641 tgaccatttg tggtgctact acgaatttga acttagggtt ttccaaacga tttccttcac
     2701 ggtcagtatc aatcgtatgg atatttccag atatctgatc cgaaatcgta tctgcaatct
     2761 gcggttgtcg ctggacaagc tgcatcgctt tcattacatc ttgccgggta atcaagcctt
     2821 ccaatgtcaa gtcatcggaa acgaccggca tgacttctag cccatcccag atcatttgat
     2881 ggctaacaga ggcaatactc attgttttct ttacactgat tggttctttc gtcatcaccc
     2941 gatcgatgat ctggtttggc gatttcccta aaacatcttt tgccgtaaca atccccatca
     3001 aacgatgatg gcggttgacg actggaaaac gcgaatgctg cgtttcttct gacaaacgct
     3061 gataatcaga aatcgtatct gtctgctgca aataatgagt cttttcagct ggcatataga
     3121 tatcactgac aagcatgata tcttttttga tcaattggtc gcttaacgct cggttgatca
     3181 tggttgcgac tgtaaatgta tcataagagg tgcgtaagat cggcatttca agatcatcag
     3241 ctagctttgc aatctcagca gtcgtattga atcctcctgt gatcaatact gcggcgccat
     3301 cttccaatgc taatttttgg acttccgccc ggttgccgac gatcattagt gatcctggcg
     3361 taatatagcg ttccatggca tgtttagtca tcgcgccgat gacgaattta ttcaagacct
     3421 tgtctaatcc tgccgccccg cctaaaacgt ccccttcaat gatcctgacg acctcgccaa
     3481 atgtcaaacg ttcaatatgt ttttttaatt tgcgttcgat acggatggtc cctactcgtt
     3541 gaattgttga aactagtccg acattttctg catctttgat tgcacggtac gctgttcctt
     3601 cactgacatt caattctttt gcgatgcttc ttacagaaat tcgattgcca acaggtaaac
     3661 tttcaatata ttctaaaatc aaatcatgtt ttgtcgccat tttctgccta cacttccagc
     3721 gtttccgaga cgctcattat ttttccttca ctatcttcca gtaactctac aaaagattcg
     3781 ggatcttgtt caatgacagg gaaagtattg taatggattg gaactacttt cttggcacga
     3841 attgtttgcg cagcctttgc tgcatcttct ggccccatcg tatagttatc gccaatcggc
     3901 aagaaagcga catcaatatc gaattcttct gcaagcaatc ctagatcact gaaataagca
     3961 gtatcccctg catgataaat cgtttttcct tctgcttgaa taataattcc gctaggctcg
     4021 cccatatact gaacgatacc gtctacttca tagcttgaac tatgctgtgc atgtacgaat
     4081 tttaccacgc cgaatggaaa cgcatgtttt ccaccgatat tcataccgaa tgaatctact
     4141 cctctgctgt tcgcataatc agcaatctca acaatactga taattgtggc ttgattttct
     4201 tttgcaatag gaatcatatc tcctatgtgg tcactatgac catgagtaat cagcaaccaa
     4261 tctgtcttta cttcttctgc agttaagtct gtcaatggat ttcctgtaat aaacgggtca
     4321 atcatcacgc gttggccatt ttccatttca attgttaaac aggaatgtcc atgatacgta
     4381 attttcatat tttacacctc gcgttttctc tgtatctttt ttattaaaaa cgatttcatc
     4441 acttgcacat caatgaaaaa atatagctgc taaatatatt ttcattggat tgatagtaca
     4501 gtatgtacaa agcaattgta acagataata caggatgcac caagtaccaa gcagatataa
     4561 tctcaagttt gaggtctctg ctctgcttag cttctcttct cgtcccttaa ctaattaaat
     4621 cagcgtaaat aggatggacg atcttttcta aatcggctac ttttatccga aggcttctcc
     4681 cgatttcacc gcttgacaca attacttctt ctttttcttt taaagaactg tctgctaaaa
     4741 aacaataatc aggatgtgcg agttttattc caataggggt gtttgctccg tggggatatc
     4801 ctgtatgcat taatacaaaa tccattccag gaaaaccaac tttacgatct ttcgtcactt
     4861 gtctcgtttt tttgtaatct aagtgatcgt tcaaaggaat caatgcgatg atcaccccag
     4921 ttttgtttcc tttcactacg agagttttac atatcaaagc tggatcaatc cctctttttt
     4981 gtagttcttc tgtgaaagat tcttctacca catgactaaa atcaagtggt tgatagctga
     5041 tcttttgttc ttctaaataa cgttcgactt ttgtttgact catcattgat tcactccctt
     5101 tattctatcg tttattataa agcgagggat gctgtattca aaaattattt gtttttcgca
     5161 aaaaaagagc aagacgagca ctctatagag aggttcatct tactcttttt gtttattttt
     5221 tatttcgacg ttgagtagct tccataatga ctggcaagat cactgggcgg cgttttgttt
     5281 gttcaaataa gtaacggcct aattgatctc ggatgtcttg ctttaatttg ctccactcaa
     5341 aatcattgct ttctaaatgt ttctcaacga ttgtttcaat catattgctg ctttctttca
     5401 tcagatcacg gctagctttt acgtaaacga atccccgtga agtaatttga ggttttgaaa
     5461 tgattttctt ttctcgccga ctgatagtga caaccgctac gaaaatcccg tcttctgaca
     5521 agatttttcg atcacgtaaa acaatgtttc cgatatcacc tatgcctaat ccatcaatca
     5581 ttacattttc tgcacttgta gttcctgcaa cactcatacg cttgttctta tattccagca
     5641 cgtctccgcg tccagtaata tagatatttt tgtatggcat ccctactgca tgagccaaat
     5701 ctgcatgagc agctaattca cgatactctc cttgaactgg cacaaaatat gttggtttca
     5761 tcaaattgat cattaattgc aagtcattag gattggcatg gccagaaacg cgcatattct
     5821 cagagatcaa cttcactgtt ccaccagctc gataaatgat atcttccgtt ttcgccacga
     5881 tggtttccat cgcgatgctt ggcgtagtag tgatataaac caaatctcct tcttcaatct
     5941 tgacattacg gtgtgtaccg tttgccattt tttgcagaga cttgatgggt tcacccattc
     6001 ggccagtttc taaaatgatc agttcttctg gatcatagtt tttcatgtct ttcaacgtaa
     6061 caagcagatc ttcacttggt aattgaagtt tttctaaacg catcgctgtg cgaataattc
     6121 gttcgaaatc ttgaccagtc aagacaactt ttcgttgtgc tttttctgct gcatccaata
     6181 cttgttgcac tcgttgcaaa ttacttgcta cacaagcgac gatgatacgc ccttcccaat
     6241 atttgatcgt atcaaatact tcatctgcta tttgggcttc agaagctaca ggctgaggat
     6301 tttctgcatt tgccgattca cttagtaagg ctaagactcc ttctttgccg atttccgcca
     6361 atcgtgcata atctgtttga tacattggga tagccgtttg gtcaaattta aaatctcccg
     6421 tataaacgat actaccttct tttgttttca gattgatccc cactgaatct ggtatcgtat
     6481 gagtggtacg gaaaaagctc actactgttt caccaaagtc tatttctgta tgctcatcta
     6541 ccacatggaa atccttaaat cctttggctg cttcattacg actgacattc aattttgcta
     6601 actcgatcgt caactctgtc ccgaatactg gtacagaaat ttttgacaac aagtaaggaa
     6661 gtgccccgat cgcatctgca tgtccatgtg ttaaaaagac accagctaca cgatcaatgt
     6721 tttcttctaa atacgtaaaa tcagggatta cgacgtcgat ccccaacaac tcattttcag
     6781 gatattttag cccacaatct aaaataaaaa tatcctcgcc cacttctgcg acatacatgt
     6841 tttttccatt ttcacgaacg ccgcctaatg ggataatttt aatggtactc acaaacttca
     6901 cctcttctta tgacatccaa gtttaaagat gtcgattttc ttctttatct aaatatatga
     6961 gccattccaa tgaagcatat gcaaaatcac tatttctcaa cttatggaga atcagcagga
     7021 aaattaccag cacatccgcg ttctgacagt tggatgggca ttttattttg gatatacttc
     7081 attaacaaaa tggatctttt gcgaaacgct atagccagaa tacttatata agtattcagc
     7141 tgttccccat tattatacaa caaataaact aaatcgctag tatcagcaat tgttagaaca
     7201 actatgcacg taaaaatccc tctgtagcat ctaggatttc ttttgctatt cctctttcat
     7261 ttcttcttcg tcggtttgaa acatactttt ttcattttac cacatttttt gcaataacta
     7321 tagtgacttt ttatatatac agaacctcat gttgatggtg tgcaaacagc ataagattta
     7381 agctagcttt aagataggtt gtctattatc aaatgcatct actaggaggg atgcaaaata
     7441 tgaattttat gaaacgtgca tggaaaagta caaaagtaaa atggggacgt tcattgttat
     7501 tgtttgccgt gttcacagcc attcttattt ttgtgctagc tggcctcacg attcgaagcg
     7561 ctgcagaaga agcagcgaat caagcacaaa aagaagttgg agcaacagtg actttaagtg
     7621 ccaatcgaga agcttcattt aaaaaacagg aacaaacttc ttcaagcggt tctaccactg
     7681 aagaacgtcc agatccaggc agtttttctc ttacaccagt ttccttaacg gacgcggaaa
     7741 aaatagctga attagataat gtaaagagtt attcctttga aagttccgcc tcagctatgg
     7801 caaaagatgg aataactgcc atcactagtt ctgattcaag tgaagacagt tcagaaacta
     7861 ctgatgcagg cggtgaacct gctggaggaa tgggcgggaa tccgcaaatg actcaagcag
     7921 actttcaaat cagtggtgtg tcagcaactg cacaaaatag taatttttct gatggaacag
     7981 caaaaatcac ggatggtgaa ggaatagatg acagcgacaa aggcacaaac aatgtagtca
     8041 ttgattctac tctagcagaa acaaatgacc tggcagtcgg agatactttc acaatcacga
     8101 gtactgaaga tgaagatacc acttatgaaa tgacgatcaa aggaatttat gaatccagcg
     8161 aaacaagcgg cagtatgggt atgaaattca acttcatgaa tccgtcgaat acactttaca
     8221 cttcttacac ttttgcaaat gaactaaatg ggacatctga cgataacacg atagattctg
     8281 ctatttacac tctatctgat ccagataaaa tggatgagtt tctcaaagaa gctgagaagc
     8341 tgatcgacac agatacattt agcttacaat caaatgattc catgtatcag tcaatgttgg
     8401 aacctttaaa caacgtggca agtttttcta aaaatgttgt tttactagtg gctgtagccg
     8461 gtattatcat acttactctg atcattatga ttaccattcg ggagcgtcgg catgagttag
     8521 gcgtcttgct atctttagga gaatccagaa gtaaaatcat tctccaattg tttaccgaag
     8581 tggctatttg tatgattctt gcattaggag ttgcttcgct tagcggaaac gtcgtcgcga
     8641 atgccgtggg acagcagcta cttgaccaac agacagaaac cacgacacaa aaccagcaag
     8701 ctcctggcgg tggacaaatg ccaggtaaca gacaagaaca aggcggtcaa cgcgatggtc
     8761 aacaaggaac cacgaataat ccatttgctg tttctgatca agtcagcgaa ttggaaatca
     8821 atgtcaaacc tgcacaattg ggactattag ccggagtagc atttggaatc agtctgtttt
     8881 ctgtcttttt agcttctata gggatattaa gattaaaccc aagaaaaatc ctattaaact
     8941 aaaggaggaa tttgatgtta cggacagaac aattgggatt ttggtatcaa gatccgcaag
     9001 atgcgcttta taaagatgta gaactgaatt tcgaagctgg aaaaatgtac gctattttag
     9061 gagcaagtgg ttctggaaaa acgacttttc tttcgcttat ttctggacta gatgcaccaa
     9121 aagaaggaaa ggtatactat caagatcgtt cactgaacaa aatcgggtta agaagttatc
     9181 gtaaaaatga tgtctcgatt attttccaag cttacaactt gcttccttat ttatcggctc
     9241 tagacaacgt catagcagca atggaaatca ctaagaccaa gcaagagaat tatcgacaag
     9301 ttgctttaga tcgactggct cgtgtaggaa ttgatgaaat attagcaaaa aaacaggtga
     9361 ccaaactttc gggaggtcag cagcagcgag tcgctatcgt tcgtgctatc tgctgtgaac
     9421 atcaactaat cgtagcggat gagcctactg gaaatctaga tgaaacaact tcacaagata
     9481 tcgtcaaact tttccaagaa atcgcccatg aacaaaatcg ctgtattatc atcgtgactc
     9541 atgagattga agtagcaaaa agctgtgatg aagtctttga actaaaaaat aaaaaatttc
     9601 aaaaaatcga agtttaaaaa acaggataat gatcaaataa aaaatccgaa ccatatctgt
     9661 ctcgcagata tggttcggat tttttatttg cttgattcaa ttagtaataa gtggttttta
     9721 ttttttttcg tcttttcgag aaaacttgtc tttgacttcg tcgcctaaat ttcgagcttt
     9781 ttctttgatg tcagcaccta gtgattgtgc tttcccttct gtttctttgc tcttgtcgtc
     9841 tgttgctttg ccgtatgctt cttttccttc accgactact ttatctttca tatctttaga
     9901 acgtcctttt aaatctgcca ttgtgcttcc tcctcttagt ttgtttattg atctaccttc
     9961 agggtaacat caacaacaga tacagacaaa cagaacgctc gttttctaaa aaagatagtt
    10021 agagctgttg attaaaaact tttttcgaaa gtcccccata ctttgacttc tttttcttgg
    10081 accattattt ctcctttagc gataactgta tcaatatcaa gcgtttcttt atccaagata
    10141 cacagatctg catcagcacc aatttcgatt tttccttttt tatccaattt caatatacgt
    10201 gctggattac tggttatagc tcgtaaggcg atttccaaag ggatactttc tttttgcaca
    10261 gcttctttga tccctactag caatgccttg gcacttccta ctcctaaccc taggaaatga
    10321 ttgttttcat caaaataagg caagcttcct tgtccatctg aggtcatcgt gaaattatct
    10381 aaagaaacat cttcctcgat caatcgtttc agtgctttgc tgaagcgaac ttcaccatct
    10441 gtcttctccc aaaaatcagg atcttcgcta gcagtgaagt caatcgtgcc accacgtttg
    10501 gcaaatgcca cgcaagcttc aaataattct ggtgtgcgat ttgcatgagt aggcaaaaat
    10561 tgtgtgatcg gaatttctgt ttcttctacg attcgtgtca atagctctag ctttcttttt
    10621 cctccgccta agtggacatt gatgatccca gcttttccgg ataacatgcc tcctacacga
    10681 gcatctgcta ctgcacgagc gaactcttca aaacttggct gagaagaacg gtgatcggat
    10741 actgcgattt ctccgattcc gataatttta tcaattgtca aaaagtcttt gatgatagaa
    10801 tctgttactg tttttaccgg caatcggtac gaaccttcgt atacataagt ggagattcct
    10861 tctgcttcca gacctttcgc tttgctgatc aacgcagtca tatctctacc ttctccgtct
    10921 gttcccaaac aaccgacaac tgtcgttaca ccagctgtag tcaattggct caatgtgact
    10981 tctggcgttc gattttgata accgccttct cctcctccac ctaaaatatg gaaatgacag
    11041 tcaatgaaac ccggggttag tacttttccc tcacctgaaa gttcttctac ttccactcct
    11101 tcgtagccgc cttctagctg ttcttctaca gccaaaatct tcccaccggc aatcagtaca
    11161 tccatttttc ctaagtaatc tggtgcaaac acttcaattt gtcgaatgat tttcatacat
    11221 ttttcctctt tctttaagta taactgatga taggatctta aaaaataatc caaacgatag
    11281 gatctttact cctttgattt taccgtaaaa tgacggttct tggagtcctt atctactgtt
    11341 tggattactt ttttatttac aggtctccag tactactgca gacctattgc aatggcaatc
    11401 atgatgaaaa tagttcctaa aacaaacagg aatccttgca tcttgatttg gaatcttgcc
    11461 cattttgccc attcgatccg tgcaacacct agcacaccaa tcaagctggc tgatacgggt
    11521 gtaaaagcgt ccataaaacc tgaaccaagc tgataagcaa gaactgctac ttgtctggat
    11581 acacctacta aatctgccag tggagccatg attggcatag tcaaagctgc ttgtcctgaa
    11641 tttgatgtaa caaccaagtt gaacaaactt tggaagatgt acatcgccca agcaccaatg
    11701 acagctggaa caccggtcaa cgccgtcccg atcccatgca aaatcgtatt caaagctgaa
    11761 ggaacagatg catcagatcc tcccaagaca agaagaatcc ctttggccat acctactacg
    11821 attgctgtac cagctaaatc agctgcacca gattggaaag aagaagcgat gtcattgact
    11881 ttcattccat ctaatttgaa aagaacagca atgattccag caactaatcc catcacaaag
    11941 aattgagaag cgatttctgg aatgtaatag cctttttgag tcacgcccca aacgatccag
    12001 acaaggacaa ctaacatctc taataagatc aatttatgcc caagcatgaa ttttttattt
    12061 tcatcagatg tctttttgat atgagaacgg aaataatcat ctgatttgta agtcaacgaa
    12121 ctttctggtt ttttacggat tttttctgca tatatcatca tataaccagc ggctaatgca
    12181 gtaacaacta cccacataat caatcggaat gtcgcaccag acaacacggg gattccagca
    12241 atcccttgag ccaccgctac gctaaacggg ctcatccaag aggtcgcatt tccgacttga
    12301 gatgcgacat aagtcacggt tactgctacg atcgagtcat atcctaacgc aatgacaaat
    12361 ggaaccatca ccattgagaa tggaattacc tcttctgcca tcccgaatgt agcgccaccg
    12421 aatgaaaaag caaagaataa tagcggtaaa gctaaacgct ccagtccctt agttttactg
    12481 ataaacgcat agatacctgc gtcgatcgct ccggtacgca taataatacc aaaagcacct
    12541 ccaacaacaa ggatcaatgc agcgatccct acagcagatc catacttatc tccagatact
    12601 agtccttcaa aaacaaaatt taagaaacca aagccgccaa aatcatctgt tccccatatt
    12661 ttggctgttt tatgcaattt tttagaagta tcatagatat tttcgccgta ctgatcgtaa
    12721 agcacatcat ctgtcaagga gatttcatct agtttttcct gcgtaagatt tttttctccg
    12781 tcagcaatga ctttttccaa tcctttttcc ggaacatcca gtttttcacg ttctgctgga
    12841 tgatcttgca gttcttctaa ttgatcaaac acatacgact tatccagctc gtaagcataa
    12901 cggaaggaat cttgacgtaa aacagtacga gtacttgttt cgccatttgc atctttgtat
    12961 tcaatatctt gcgtgctgaa ctttcctgct ggaacgacaa aagtcagtat ccatgcaaag
    13021 atgactacac caaaaataat gacatacgta tggggtgtcg ataatttagt gaagtcgcgt
    13081 ttcggttttc ctgaagaatt tgttttcttc aaatttattt cttcctttct tttttcagta
    13141 attttgatga ataaaaaatg gataatcaaa tgaattatac agtaaaaatg acatttccac
    13201 atgaataatt tattagaaaa tcactttttt ctattttgtt ttttttctcc tatgtatgat
    13261 tatttttttc tctttccatt tatattaagt attttatttc tctgtttttc cttaaaattc
    13321 tttttttatt tttagattag agaaaatctc gtcctgtttt tttcatttta caatcattga
    13381 aaaattgaat ttcattgcaa aaaaaataat aaacacttat aaatatccat tatctatcct
    13441 tcaatttttg tgtattttat ttctattaga aaaaggtatc ctgttggaca attttgttat
    13501 atcaggtaaa cttcattgca ataatgataa caaatgtact ataattactt tgtaaagagt
    13561 tttggggaag actctttcat caacgtgtat taagagacaa gaaagaatcc atatggattc
    13621 tttcttgtct ctttttccac tactttttat ttttctgaca ctacatattc ttataactca
    13681 tttctcataa ctgtgaaaca acttataaaa ataacaaact ttaaacaaaa caagcttaaa
    13741 atcaaagatg atccatctta aaataactaa aacaaaaaaa gtagtcgttg ttaatcctca
    13801 ttaataatcg ttttcttttt ttcaaacgct ccatttttat gtggaacatt atttttttaa
    13861 ggaactttgt caacatgtgg ataactattt tccacttgtg tcctggacta gctgttttgc
    13921 tgtaaaatac aaaacttgct gcagcaaaaa gatcgttgca agagaggctg ttccgcagat
    13981 cgctggatct agatttggca aagtcaagac tgcatcatgt aaattggcgt ggttgtccaa
    14041 aaccaaatca gcaaattcaa ataatcgcaa accactgcta tgttgcgatt tgatacttcg
    14101 tgacaaatca aatccagtaa caatgattaa tggatgacca ttttctttga tccactgagc
    14161 tagttcgatg attgccgggt ttcttccttc attcgaaaga agaagaaaaa tgtcttctga
    14221 tttgacagaa agctgatcaa taattgcctg tcctgcacct tctagcgttt catagacacc
    14281 tccggctgga ttttcaatca atatacttgg tacaagatcc ggggtttgat cccaaaattc
    14341 aaatgctaca ccacttagtg tgcggctagc atatatctgc aatctaccac cttgattaat
    14401 ttgtttcgcg atccaagtgc cagcttgaag catcagcggc tcttctatcc ttaatttctc
    14461 ttccaattgg tgataatagt caaaataaca taaactcatt tatctctccc gcctagctat
    14521 acttgacatg aatagaaaca gctgcctaat ctaaggaagt acataaaaaa acagtagtta
    14581 gacagtaaca catgtggtct ttgctgtttc aaacacaaaa aaggcattga acgaatacgc
    14641 ccaatacctt gacatagcaa ataaaacaac gtgcagacca tggaaaatat ctacataggg
    14701 gtagaatttt caccctagat taggtacaat aaattaggtc gatgcactgc attgactatg
    14761 gcaaaatgat cggtcagggt gtatgtgtgt gactggtcat tccctgattc ttagcgccaa
    14821 ctaagggtca gggagccttt ttttattcag ctgtttctat ctgaatttat tgtaagtaat
    14881 ctcttatcca agtgcaagca agaaaataca aaaaaacatt ggtatgattt atatatatat
    14941 aaataacata aaaaaaggaa tggcttatcc cgatacaaca agcattcctt taaaaaagat
    15001 tcttttatat aagtgaaaaa agcttttttc caccaattaa ataaatctct catctcaata
    15061 gtttatccat tattttatct ttttttgcgt atacctacta aatattaccg tcttcttctc
    15121 gttcttctac tttgttcgag agaatctgta ctagaaaaag tagttgtatg tctacctttt
    15181 ctgcctatcc gagactttct tttcatatat gggatataaa tgattagata cagtacagca
    15241 aaaaataaag caaatacgca agcttcccaa ctacctaacg ccaattcaac catcaaggta
    15301 gcaaccccaa cggatgctgc ataccagata aaaatcagaa acgtttcttt ttttctgacc
    15361 atgcgaaaca tgataaatag actaataagc aatagtggca acacaaatat ccaattgctt
    15421 ccttccatca gccacttgag tatatcaagc agcgactgtg caacagcgac taattttccc
    15481 atagtgaaca cacacctttt tttataatta aaaaattcgc ctttttattc tactatgaat
    15541 cttctggctt ggctttcatt tctcttatgt aatcattttc ttttatacaa cttaaaaaaa
    15601 aattaaacca ttagcataat attttctgaa tctattcacg aaagtctttt tctatctttc
    15661 gttttccacg actcaactga tctagagtca aaaaactaaa acgacagttg cgcaaatgac
    15721 gcacaagctg ccgctttaat aacaaatagc ctttcattct cagcaggcca cttatttcca
    15781 gttaactttc tgttcttagc tttttactca actggataat atatgcactt aatgaagtcc
    15841 caatttccga atgttgaagt ccatattcaa tatttgtctt catatatcct aacttatcgc
    15901 ctacgtcgta tctttttcct ttaaactctc tcgcatagac cgcctctgtc tggttaagag
    15961 tctgaagtgc atccgttagc tgtatctcgt ttcctgctcc tggttcttga gtttctaata
    16021 tctcaaatat tttaggagtc agtagataac gtccgataat ggctaaatta cttggtgctt
    16081 ttcccatttc aggtttttct acaaaccctt ttactctgca acgacccttt tcgctatctg
    16141 ttttaggatc aataattccg tatttagatg tttcattttc tggtacacgc atgacggcaa
    16201 cagcggaagc ttgtgtttct tcataatcca tcatcaattg ttgagtcaat gggatatcat
    16261 ctttcatcaa atcatccccc agcatgacga caaacggttc atttcctata aatgcttttg
    16321 cttgaagcac ggcatccccc agtcctcttg gatgagattg acggatgaag tgaagattga
    16381 cttgagtcgt ttcttcaact aaagcgagta attctgtttt ttccttttcc cgcaaattgt
    16441 tttccaattc gatatttgca tcaaagtgat cttcaatggg tcttttttct tttcccgtta
    16501 cgatcaagat gtcttcgatt cccgaatcca atgcttcttc cacaataaac tggatcgttg
    16561 gtttatccac gattggaagc atttcttttg ccatggcttt tgttgccggc aaaaaacgtg
    16621 ttcctagccc agcggcagga atgactgctt ttttgacctt cactt
//
LOCUS       DAFTHM010000057        16389 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFTHM010000057 DAFTHM010000000
VERSION     DAFTHM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.057"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="L7C88_001794"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="L7C88_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBP9558612.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="L7C88_001795"
     CDS             complement(680..1666)
                     /locus_tag="L7C88_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBP9558613.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="L7C88_001796"
     CDS             complement(1689..2255)
                     /locus_tag="L7C88_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBP9558614.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="L7C88_001797"
     CDS             complement(2269..2685)
                     /locus_tag="L7C88_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBP9558615.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="L7C88_001798"
     CDS             complement(3142..5076)
                     /locus_tag="L7C88_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBP9558616.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5357..6313
                     /locus_tag="L7C88_001799"
     CDS             5357..6313
                     /locus_tag="L7C88_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBP9558617.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="L7C88_001800"
     CDS             6403..7506
                     /locus_tag="L7C88_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBP9558618.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="L7C88_001801"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="L7C88_001801"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBP9558619.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9407..10753)
                     /gene="gor"
                     /locus_tag="L7C88_001802"
     CDS             complement(9407..10753)
                     /gene="gor"
                     /locus_tag="L7C88_001802"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBP9558620.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10887..12140)
                     /locus_tag="L7C88_001803"
     CDS             complement(10887..12140)
                     /locus_tag="L7C88_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBP9558621.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12146..13069)
                     /locus_tag="L7C88_001804"
     CDS             complement(12146..13069)
                     /locus_tag="L7C88_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBP9558622.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13290..15782)
                     /locus_tag="L7C88_001805"
     CDS             complement(13290..15782)
                     /locus_tag="L7C88_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBP9558623.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15789..16256)
                     /locus_tag="L7C88_001806"
     CDS             complement(15789..16256)
                     /locus_tag="L7C88_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBP9558624.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         4821 a         3422 c         2919 g         5227 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg atggcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtcttg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttga tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtgaaaaag tcgcttagtt tcgagtatta
     8761 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
     8821 aactggcttt tgaacaccgt ttatcagagg ttgtaaaatc agtgttttgt cctgagtatt
     8881 agagaaacaa atggaaaaat agttcctcat attttgccgt tttttgagct aataccgaag
     8941 gacagctgat tgaacactat ttgttcggaa aaagtgacta actatgacac aatttttttc
     9001 acagtccctt ttttcacttg atttgattcg taccagcgaa cttgacgaga actttcttgg
     9061 tttggtaact atatggtatt cttttaacat cctcgtttgc ttcttctaat ttatttatac
     9121 aaagtcacac ttttttaaac atctgttctt cgatacattt ctatttcttt taaacatcga
     9181 taccaatatt ttgaacttaa gagtgcatac caaatggatt catttactct tcgtcagtta
     9241 cgaagataat caaaatctcc aacttcccta cttatttcgt tttgagaatt atcgaagcaa
     9301 tcttacataa ataactaaaa aacaaaaaac cagaaaatca gtatactgat tttctggttt
     9361 tacatggttt gttcaataaa aagctgttgg aactgttaat attaaattat cgcatcgtta
     9421 cgaattcttc cgctcctgtt ggatggatgg ctactgtatt gtcaaagtct tctttagttg
     9481 cacccatctt gatagccacg gcaaaacctt gcagcatctc atcgacacca acaccaatag
     9541 catgtaagcc gacgattctt tcttcttttc cgacacagat caatttcatt tcgcattttt
     9601 ggcgataatc atttaatgca aagtacattg gggtaaagcg tgaacgataa actttcaatt
     9661 cattttcgcc atatttttcc aatgcttctt cttctgtcaa accaattgtt gcaattggtg
     9721 gatgcgtaaa gacgactgtc ggaacaagtt tatagtcaag ataagaatct ttctttccat
     9781 taaataaacg ttctgataaa cgtctaccag ctgcgattgc aacaggagtc agatctaatt
     9841 taccgatcac atcaccaaca gcaaaaatat gttcatccgt tgtattttgg tatttatcta
     9901 ctttgataaa cccttttttg tccaattcca catttgtatt ttccagacct aatttttcgg
     9961 tattcggtac acgtccaccg gcaaaaagta cacaatcacc agttaaggtt tcaccatttt
    10021 caaatagcac cgtatattcg tcattgtttt tagtaatttc tttagcaata tgatgtgcgt
    10081 aagtttttat tccagcttct tggtacattt ggatcaaatt gtccgaaagc attttatcaa
    10141 acgttctaag tggtcgttct tttcgatatg cccacatgac ttcactacct aaaccacgaa
    10201 atacacctga aagttcagcc gcaatgtatc cagcacctaa aacgattgct ctcttaggta
    10261 actctgttaa ttcaaaaaat ccatttgaat caattgcgta ttctccacca ggaatggtca
    10321 ttttacttgc acggcctcca gtagcgatca agattttagg agcacgatag gtttcaccgt
    10381 ttacttcgat cgtttgacta tcgataaaag tagcgtaacc ttttatagcc tcgacatgat
    10441 tgctatctaa tcctctttga taagcaccgt gtagaaaatc aatatatttt tctcgtcttt
    10501 ctactagacc ggcgaaatca acatttttta aatctgcttg gataccgtaa cttgaggcat
    10561 ctcgttcaat tgtttccaaa atcgtacttg cttgccacat aactttttta ggtacacaac
    10621 cgacgttgac acatgttccg cccaattcat tcgcttcaat cagcaaaact tttgcgccat
    10681 gcatccctgc tctgtttgct gaagcaatac cgccagagcc gccaccaatt acgatgtaat
    10741 catatatttg cattttgttc ctccttattg aagagatcaa tcaaaacctt tatttaacga
    10801 tcctttttct acagaaaaca agtgtaacac ttttcttgaa ttttgtatgc gaagatgctt
    10861 aaaacaggga tatatcagct ttttccttat ttacgttttc ggatcatatc tccaggtttc
    10921 accggctgtg cgactggcat agttaaaatc atcattggat ttggtgctcg gtcaatggat
    10981 tcgccttctt cattatgcat aacttcaacg gtttgactga aatgactgaa tcctggacca
    11041 taaaattcga tttcatctcc tacagaaaac aagtttctct gacgtatcgt agcaatctgt
    11101 gttgcctcat cataagataa tacttcaccg acaaatttat atactgggat tttacgacgt
    11161 tcaccgaata attgttcgtt ttcagttggt gtattgtagt aaaaacctgt agctaattct
    11221 cgttgtgcta ctttccataa ctcgtcgatc cattcttgct tgcagacata gttttcagga
    11281 tcttccatat aactgtctac agccgcttta tagacatttg acaccgtaga tacataatgg
    11341 atcgatttca ttcttccttc gatcttgaag ctgtctacgc cgttttcaat caattctgga
    11401 atatgttcga tcattgacat atccactgca ctcatcgaga attcttcttc cacttcgcct
    11461 gtatcagtta aactgtttcg ttcttgacca aaaggcatat cgaacaatcc atacttccag
    11521 cgacaagatt gagaacatcc gccacggttt gcatcccgca tcgacatatg gttggacaat
    11581 gtgcatcgac cagaataaga gatacacatg gcaccatgga taaatgcttc gatttcggta
    11641 tccgtatttt tacgaatctc tgccacttcc tccattgaaa cttcacgagc taaaacgaca
    11701 cgttccaacc cttcttcttt ccagaattcc aatgtctcaa aattagttgc tgaagcttga
    11761 gtggataaat ggatcggcag acctggggct tctgtcgcac aaatttcgat caaagctgga
    11821 tcagaaacaa tcactgcaga aataccgaca tcacgcaaac tgcggaaaaa ttcccctgct
    11881 ccatcttcat ttccttcatg ggtgaccata ttagcagcaa cgtatacctt cgcatcatgt
    11941 tcttttgcaa aagcaactcc ttcagccatt tcttcataag taaaattacc tgcacggctt
    12001 cttaaaccat atgcattccc gccaatatat actgcatctg ctccataatg gatcgcggtt
    12061 tttaactttt ccagtgttcc tgctggcgct aggatttctg gtcgtttcaa ttttcttttt
    12121 actgtcattt ctttcatcat actccttatt tgatagcaga aggatcaata taaaagaatc
    12181 ctgtatctaa ttcacggttt tcaggatgca atttactgat ttcgctagtc attttttccg
    12241 ctttttcttg atcccagcta ccttctaaaa tttgtttttt tgcttcggcg aatagtcgag
    12301 tgatgtttac gaatttttcg cctggagtaa ataatccgtc caatttccat gtacagtaat
    12361 gatgctgata aagttcattc aattcattcg agagattcag atcattgctg gcaaaaatat
    12421 gtgtgccatg actatcttca taaatagaat aatgtgtctc ttctttttta ggttccgaga
    12481 taaaaagacc tctttcacga tctttttgtt cgtcttgttt cgtatagtta tagtaattct
    12541 gtagcagtgg acgtttggat tgatggatgc atgtagcacc atacacaagg gtttctacag
    12601 gaatatcgag tttttcttcc atcgccttca tctcttcaaa aggaacttca cgagcaagta
    12661 ctgctccaac tgcgcctttt ttcgcccaga aattgatttg acgtgcgctc gttactaatg
    12721 tttcagcatc ataaatatac ggtatacgca attcaggatt ttttttcatc gtataaataa
    12781 tacctgtatc accaactgtg atcacatcta cgtttatttc ttttaaaaaa gccaaatatt
    12841 caggtacatt tttcattttt tcaggatgaa tgatcccatt tacagcaata ttcgcttttt
    12901 taccatactt gtgtgctaat tctaccaatt gtcgctgttc ttctcgtgta aatgaagcag
    12961 gcagacgcaa tccaaattgc tcttcaccga aatatagtgt atctgcacct gcagcaagca
    13021 actgttctgc ttgttcaata gtttctactg tggttatgag ttcgatcata attttctcct
    13081 cctacaactt cataatagta gcatagctct aaaaactttc caatacttct tctatttaaa
    13141 gtcggatttt tgaaaattat ttcacaaaaa atcaaaataa agttcgatat attctgtcca
    13201 aatataaaaa gagattgtga caaaaatctt gtcacaacct cttaatcaag tcttactatt
    13261 ataaaaattc agctacacag gccaagtaac tatagggaac ctactgtttc ctttttaggt
    13321 ccgcgaacat tcaatgtgat cttacctttt gaagcaccta ctgttacgtg gtcacctaaa
    13381 cgaatttctc cgccaagcaa agcctcgctc aatcgatctt caatttcttt ttgaagtgcg
    13441 cgacggattg gacgtgcacc atattcagga tcaaatccag ctttcccgat cacatcgatt
    13501 gcagatggtg tgattttcac ttgaatatct tgttctttca atcgtttgat aatcgctttg
    13561 ctcatgattt ggacgattgt atggatttca tctttactca atgaatggaa gacgacagtc
    13621 tcatcgattc gattcaagaa ttcaggtcgg aaagctttct ttaactcttc taagatacgt
    13681 ttttgcatgg ctttgtgatc tttagtaaca tcttggacat tgaatccgac atttttttct
    13741 tctcgaattt gtgtcgctcc gatatttgaa gtcataatca tgattgtatt tctaaagtcc
    13801 acttttctac ctttagaatc tgttaaatga ccatcatcca atacttgcag aagtaaattg
    13861 aaaacgtctg gatgtgcttt ctccacttca tctaagagaa tcactgaata tggtttttga
    13921 cgaatttttt ctgtcaactg tccaccttca tcatacccta cgtatcctgg aggagacccg
    13981 attaatcggc ttgtactgta tttttccata aattctgaca tatcaacacg gatcagggca
    14041 tcttcacttc caaacatgac ttctgaaagt gctttggcca attctgtttt tccgacacca
    14101 gttggtccaa ggaacatgaa tgaaccaatt ggacgatcag gatctttcaa tccgcttcgt
    14161 gcacggcgga tcgcacgtga aactgctttg acagcctcat cttgaccaac gacacgttca
    14221 tgcagaagtc cttccagttc taacaagcgt tcgctttctt ttttctccaa ctgctgtaga
    14281 gggacaccag tccactccga tacaactgta gcaacatctt cttctgttac acgatcagaa
    14341 taaccttgct cctgttttgc ttcaattgca gaaacttttt gcagcttttt acgtagtgct
    14401 ttttcttgtc tgcgtaattg agcagcattt tcaaagtctt gtttttggat cgctgcttcc
    14461 ttttcttgta ctagttcatc gatttctagt ttgatcacag ttgattttgt taagtgatcg
    14521 gtttgatcca aacggacttt cgctgctgat tcatcgatca aatcaattgc tttatcgggt
    14581 agttgacgag aagtgatata acgaacagaa agattgactg ctgctcgtac agcttcatct
    14641 gtgatctcca ctccatggtg ctcttcatat cttgtacgta atccttgaag aatcacttct
    14701 gcttcttcag gagttggctc atctacttga atgcgagcaa aacgtcgctc taatgcagaa
    14761 tctttttcga tatatttttg atattcatct agggtcgttg ctccgatcgt ttgtaattct
    14821 cctcgagcta acgccggttt caagatattc gaagcatcaa ttgctccttc tgctccacct
    14881 gcaccaatta aggtatgcaa ttcatcaatg aataagatta cttgaccatc attatagatt
    14941 tcgtcgatga cctttttcat tcgatcttca aattcaccgc gatatttcgt accagcaacc
    15001 aaagatccca tatcaagcat catcaggcgc ttttcttgca tgtcttctgg cacttcacct
    15061 aaaatgattt tttgagctaa cccttcagca atggctgttt tgcctacacc aggttcaccc
    15121 accagtacag ggttattctt tgtccgtcgg ctaagaatct ggataagccg tttcacttct
    15181 ctcgaacgac caacaactgg gtccagcttg ttttcttttg ctaatttcgt caaatcacgt
    15241 gctaatgaat ctagcgtagg tgttccttgc ggtgtttgcc gtttatcttg tacatttaca
    15301 tttctacgac gattcattcc ttttccagca gaatcaccag ctagccccat tttttgtttc
    15361 agaacttgac gggcttttga aaggctgata cctaagttga tcatgattcg agtagccatg
    15421 atactttcat cttttaataa gctcatcaaa atatgttctg ttccaacttt ttgagaacca
    15481 gttttcttca cttcgctgct agctaaagca aaaacttgtt tcattcttgg tgaatatgga
    15541 agaaagactc ctttagggta agaacggata ccaccataac caatcagatg ttcaatttct
    15601 tcataaattt ccgtttcatt caaatccatt tcacgtaata cttttccagc aattccattt
    15661 tgctcgacca ctaaggctag taaaacatgt tctgaactaa ctgattgatg tttcaaccgt
    15721 tttgcttctt cttgtgcaat ttctaatact gcttgggctc tttcagtaaa aagttcttcc
    15781 atctaatctc acttcccatc ttcataactt aaacgttcca gaaatgctcg gagaatccga
    15841 gcacgtgtat gatcttcata ttcattgaaa ttcaatgtgt tttttgcaat tgcactcaac
    15901 atcaagtttc cttctttttt tgtaattatt tggtcttcat aaagtttttg aataatagca
    15961 aaagcatttt tctcactgat tgtatcatca aataactgat ttatctgctc aagtaattgt
    16021 tttttatctg aaatccttac ttttgcaatt cgtatataac caccaccacc acgtttgctt
    16081 tctactagat aaccacgttg gatggtaaaa cgggtattaa tcacatagtt gatttgtgaa
    16141 ggaacacagt taaagaggtc tgccatttca atccttcgaa tctcgatcat ttcactattt
    16201 tccagaattt tctttatata tgattcaatt aaatccgagg tattctgatg tgccatctta
    16261 ttcattccct ttgactaata ttgaccttaa ttataacgaa tttgataata gaaagaaaga
    16321 agaacgcttt ttgttaaata aatcctttag aatcaacaaa aaaaaatacg gaatatacta
    16381 ttccgtatc
//
LOCUS       DAFTHM010000058        16245 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFTHM010000058 DAFTHM010000000
VERSION     DAFTHM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16245
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.058"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..396)
                     /locus_tag="L7C88_001807"
     CDS             complement(<1..396)
                     /locus_tag="L7C88_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBP9558625.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGV"
     gene            complement(526..1236)
                     /gene="budA"
                     /locus_tag="L7C88_001808"
     CDS             complement(526..1236)
                     /gene="budA"
                     /locus_tag="L7C88_001808"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBP9558626.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNIQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(1249..2913)
                     /gene="alsS"
                     /locus_tag="L7C88_001809"
     CDS             complement(1249..2913)
                     /gene="alsS"
                     /locus_tag="L7C88_001809"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBP9558627.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(3121..3783)
                     /locus_tag="L7C88_001810"
     CDS             complement(3121..3783)
                     /locus_tag="L7C88_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBP9558628.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKENSFSPVRLFIKMFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSTNCWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(3793..4608)
                     /locus_tag="L7C88_001811"
     CDS             complement(3793..4608)
                     /locus_tag="L7C88_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9558629.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(4869..5312)
                     /locus_tag="L7C88_001812"
     CDS             complement(4869..5312)
                     /locus_tag="L7C88_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBP9558630.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     HSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(5446..5784)
                     /locus_tag="L7C88_001813"
                     /pseudo
     CDS             complement(5446..5784)
                     /locus_tag="L7C88_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(5772..6149)
                     /locus_tag="L7C88_001814"
     CDS             complement(5772..6149)
                     /locus_tag="L7C88_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBP9558631.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            6373..7566
                     /locus_tag="L7C88_001815"
     CDS             6373..7566
                     /locus_tag="L7C88_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9558632.1"
                     /translation="MTTYQRKVLVSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFVMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(7732..8154)
                     /locus_tag="L7C88_001816"
     CDS             complement(7732..8154)
                     /locus_tag="L7C88_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558633.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQQYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            8737..9231
                     /locus_tag="L7C88_001817"
     CDS             8737..9231
                     /locus_tag="L7C88_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558634.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQAA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(9393..10565)
                     /locus_tag="L7C88_001818"
     CDS             complement(9393..10565)
                     /locus_tag="L7C88_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBP9558635.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEGSSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(10771..11586)
                     /locus_tag="L7C88_001819"
     CDS             complement(10771..11586)
                     /locus_tag="L7C88_001819"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBP9558636.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(11736..12182)
                     /locus_tag="L7C88_001820"
     CDS             complement(11736..12182)
                     /locus_tag="L7C88_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBP9558637.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(12179..13183)
                     /locus_tag="L7C88_001821"
     CDS             complement(12179..13183)
                     /locus_tag="L7C88_001821"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBP9558638.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(13223..13552)
                     /locus_tag="L7C88_001822"
     CDS             complement(13223..13552)
                     /locus_tag="L7C88_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBP9558639.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(13678..16005)
                     /locus_tag="L7C88_001823"
     CDS             complement(13678..16005)
                     /locus_tag="L7C88_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBP9558640.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         4643 a         3232 c         2886 g         5484 t
ORIGIN      
        1 tactccgcaa tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac
       61 gatttctgat tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc
      121 aacgatcaat gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat
      181 acgtgtgcaa gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa
      241 ataatatcct gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc
      301 taaatttgct aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat
      361 ttcgtatgca tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc
      421 tatggagaag attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg
      481 agatacgtca ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg
      541 gatttctgct gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac
      601 tggaaaatgc tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc
      661 aaaatccatt acatgtccgc caaatgtatg tgtatcatcg ataaaatgca ggtgaaatcc
      721 cgctgcagca actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggat
      781 attgctttgt tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt
      841 ttcttgcttc ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc
      901 caaaaatagg ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc
      961 tgcagttttt gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg
     1021 ggtaagttca cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac
     1081 gccatctaaa aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc
     1141 tttttctaat atatgagcaa tcgtttctgt tccatccatc aagccggcca tcaaagctcc
     1201 taatgtcccg tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg
     1261 atctggtaag attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat
     1321 aattacgggt ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact
     1381 tgtagctcgg attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc
     1441 aaagtctaca cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta
     1501 gtgtccatca ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa
     1561 atcctgggca gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg
     1621 acgcaccaat gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt
     1681 actgaataac aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg
     1741 actacctaca tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat
     1801 aacttctaaa ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt
     1861 taattttgct tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc
     1921 taatgaacct gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg
     1981 ctgcataaaa ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt
     2041 ttccgcattc cagtttcttg cttcatattc gattggatca tagccaattg caataactag
     2101 atcacttcgt ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa
     2161 gaaatgcgct tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg
     2221 caatgctgtc ttttcaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg
     2281 catacctact aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat
     2341 atcatctgca gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattaccttg
     2401 gacaggtgca tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact
     2461 cttagccata cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc
     2521 tgcactgtat tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa
     2581 cttcaataga tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc
     2641 tgtcgctgtt accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac
     2701 tactcctggc tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc
     2761 gtgacgagtc acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat
     2821 ttttgcacct ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac
     2881 agatttcgaa ccttgtttca ttttttcagc cattgaacat cgtccttttt atgctttatt
     2941 tttaattatt agttagaaat aatcacaaat aagtgataca gtttctaaac ctgtttcata
     3001 caaaagtata gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga
     3061 atgacagttt ttacataaaa aaaactgtca ttcttaattg aaagtttcaa tttataaagt
     3121 ctacagatcc atagttctca tcaatttacg attgttgaag taaatcaaac caaatacgat
     3181 agaaggacct agtagaatac accattgggg ctttacgaaa aagaagagaa acaaacttgt
     3241 caatagtaaa aaatctagta aactcacata ccattttttc aacgtatagt agaacgctat
     3301 ccgtagaact tgatttggtt tcgacgctgg atttctcacc tgaaaatacc agcagttggt
     3361 gctaaaggaa actgataaac aagcaagtaa aacaaacaac ggaatcaacc attttccata
     3421 agaaaaacgt ataaaaaaga aacaatcaaa aatcattatc acactaacta tccaagcaaa
     3481 tagccaataa aaaaatccct ttagccaaaa ttggcgaaac atctttatga acaaacgtac
     3541 tggtgaaaaa ctattttctt ttgctaattc ttctgtcata cctatcatca cgatgcaacc
     3601 tggaccaata aaaagtaaag aaaaaataaa ggaaaagaca ttccttccat ctatcgacaa
     3661 aaggaacgca gctgctatat acaagatatt gacacaccaa aaacaaaggc tacttgccaa
     3721 tgattgatac aaccaataaa agaattccat ataaacattt ttgtcaaaac gctgctcttt
     3781 cataatcacc tcctattcct tcattcctga tgaagcgatc ccttctacaa aatatttttg
     3841 catcgctaaa aatataaaag caacaggaag aacagaaaca actgaggcag ccatgattaa
     3901 tgcgtactct gcatcaaata gcccaataaa cattttcaac cctaactgga ttgttttatt
     3961 ttccgtagaa gacaaataaa tgaatggccc catataatcg ttccatgtat taacgaatgt
     4021 gatgatcgtc aaactggcaa tcgccggttt tgtaagaggt aaaatgatct tgcgatagat
     4081 tccccactct gataagccat cgatccgcgc actctcacat aaagaatctg ggatactact
     4141 gtaatattgc ttcaacaaga acacaccaaa agcattgaac gcttgtaata gcaccaacga
     4201 ccacaacgta tctgttaaac ccacttttct catcataatg aactgcggga tcatataaga
     4261 ctgccaaggg acagcaatcg tgccgatata tgctaaaaat aaaatatcgc gccctttaaa
     4321 atttagttta gaaaacccgt aagcagcaaa actagaagta aacaactgaa tcaacgtgat
     4381 cacaacgctt aaaaaagctg tattcttaaa aaatgtcact aaaggaatac gagaccaaat
     4441 aaccagataa ttctctaaat gccaagtttt agggatccat tgaatcggaa tcgtgaacac
     4501 ttcattattt gctttgaatg aagcagaaac catccataaa aaaggaatga tcgtcaataa
     4561 agctaataca atcagcagaa tcatacccaa ccattgaata aagggcatgt tttttgaacg
     4621 aatttttgct ttttttcttt catttcgaac acctccaaag ttataatctt catttctttg
     4681 taatgattac aatccagaac aacggttatt atagctgatt catttccgtt cttcttattt
     4741 ttgtaagcgc ttatttaaca agttatgtaa atctctttat ttttttgatt taaaaatgaa
     4801 aaaatacaaa agcaagactg tcatacgtct cgcttttgta ttgaaatttc ttcgattaga
     4861 gatacttatt actgttcaaa agcttctttg aaacggtgaa tcaattcatt gactacaggt
     4921 gataaaatcc gattcttttt ccagactagc atgcagttcg tttcaatcat tgggtcaagc
     4981 ggaacgaatg tcactcgctt tgaatgatga cttacagcac cttctatgac taaagcagca
     5041 cctacctgat tctcaattag cgcaaataca ttgaaaatca aattgtacgt tcctgtgatc
     5101 agcaactgct ccttttttat gcctaaccag tcagcaaaca ttcgctgtat ttctggacgc
     5161 tttgagatca aaagaggtac attcgcaaag tcttcttttg ttatcacgtc tttttttgct
     5221 aaaacagaat tttctaaaat gagcaatccc catttttcct ttcttggtaa caaaatcgtt
     5281 tcgtatttct ctgtatctac tggatctagc aaaatcgcta aatctaacag gcttttttct
     5341 agtcactccg tgatatcatc acttgttccg ctgtggatat gaaattgaac gctgggataa
     5401 tcacggatca acttttctag taatagtgcc aatgtattcg aactatcagc ttccacacag
     5461 ccgatcgtaa atcggccgct gaataattgt ttttttctgt tctcgaattc ttgagtggtt
     5521 tgattcgtta aatctaaaat ttcttctgct cggctttttt agaaaataac ctgcttctgt
     5581 caagatcatt ttgcggtttt cgcgtacaaa cagttctgtt cctagttact cttctaactc
     5641 cttcagttgt cggcttaagg ttggttgtgt aagatgtaga acttctgcgg cttgagagat
     5701 tgttccttct tctgcaattg tccaaaaata ttttagtaag cgtaactcca tagcgatgct
     5761 ccttgatttt tttacttgat acattccatt ttatttctag ataacacacg atcatatttc
     5821 ttgatttttc cttgtaaacg ttccaaacat tcttgcattt cagcaatttt tttcgtcaaa
     5881 agttcacttt cttcaatcaa aagcttacgc cgctcaaata cagttgcttc tccttcgcta
     5941 gataggcgaa tatattcaat caaagactcg atcgataatc cggcatttcg catacagatc
     6001 gtaaagtcga cccattttag gtcttcttct gtataatcac ggattccgcc ttttgtccga
     6061 ttaactggtg gaatcaaccc gattcgttca taatagcgca atgtatcggc cgaaatgccc
     6121 ttttcttcac tgacttgttt gatattcatc tgatcactct ttctcttaat ttcttgccac
     6181 tttacttatg tattttattt attctacaac tttaagtgta ctccaagtca atactcattt
     6241 ctattaaaac taagctggat tatctatatc ggttgtttgt gtattatttc aaataaaaaa
     6301 gtcttgtttt tttattcttt tttggatata cttttaacaa tttagggaaa ttttaggaaa
     6361 aggggtataa aaatgacaac gtatcagcga aaggtattag tatcgacatc ggcgggaatt
     6421 gctttagaga atatggatat tatgttttta gctttttcat tatcttcaat gattacttct
     6481 tttcatatta gtggtacgca agcgggtttc atttcaacga tcactaattt ggggatgctc
     6541 attggaggta ttttttttgg catcatagct gataaatatg gacgtgtgaa agtattttct
     6601 caaacggtcc ttctgttttc gattgcttct ttattgatgt attttgcttc aaacatctac
     6661 ttggtttatc tctttcgctt tatcgcaggt gtaggagcgg gaggagaata tggggcgtgt
     6721 atgtccttga tttccgaaag tttttcaaaa aaacaaattg gacgagcttc ttcggttgct
     6781 ggtattggtg cgcaggtcgg tgcggctttg gctgcgattt tagctgctgt gatcattcca
     6841 acgtttggtt ggaagatgtt gtatgtcgta ggtgtactgc cggtgttgat ggtcttgttc
     6901 attcgtcgcg gcttgactga accaaaggaa ttcaaatctg tacaatctgc cgaaaagaaa
     6961 accaaactta gcagactgtt tgaatcaaaa catcttgctt ggcaaacatg tggccttagt
     7021 atcatggtaa ctgtccaaat tgccggctat tttgggttaa tgaattggct accttcaatt
     7081 atgcaaaatc gattagggct ttcggtttct gggtcttcat tgtggatggt cagtactatt
     7141 ttaggcatgt ctttggggat gatgactttt ggcataatca tggataaatt ggggcctaaa
     7201 ctagcctttt ctttgttttt aatttgttca tccttatctg tctatctact tgtgttagcc
     7261 catagccagt ggagtttggt agcagccgct gtgatagtcg gctactttat caatggcatg
     7321 tatggtggat atggcgcagt gattagtagt ttgtatccaa cagaaatccg cgcgacggcg
     7381 aataatttcg ttatgaacct tggacgagct gttggtggtt tttcttctat cgtcatcggt
     7441 ttcttgatgg atcattatag tttaactgcc gtaatcttgt ttttgagcgg tatttaccta
     7501 gtcagtctgc tggtcttgac aactcttact ggtgttacag cattaaggga aagcttgcag
     7561 cattgatagt tgagtctgta aatgacaaga aagaggtgtg gaaaaagctt gcatctgcgg
     7621 taataagacc agccaaatca aaaacatgag acactgtttc cgtttggctg gtcgtattac
     7681 ttgatgcagg gcagcttttt caactgctaa tttccttcta tctggcggcg actattcttt
     7741 gacgtccgtc atttcaaagt actttactaa taacttagca taacgaaaaa ctgtggatac
     7801 actcgtatat tgagcgtctg cataatcttc caaatttttc tcaggatgtt gatacatgaa
     7861 ttcaatcaaa tgataattat atgattttct gtagaaatga agataaataa tgtagattgg
     7921 gaagttctcc tgcttttcca tagaaaagcg ccgattattc tcattcttca aaatgacctt
     7981 atcaggatat tgttggaaca attcttctaa atctgttaga taattcaaga tagacttact
     8041 tgataccttc aattcgtttt gtagttcttc tattgaacac caacgttctg tttcaagcag
     8101 taaatgaatc attttaattt tcttttgaga aacttttgtt aaaaaagtct gcatattttc
     8161 tcctcctgta tctactttac tatactacat acaagaaaaa aacggataca aatatcatat
     8221 tgtcacaccg tcaatagtgc ataaacctgt tattatttct ctttttttcc taagtattct
     8281 attgatatga atcatttaat cgtttattat ataaatgtca ataatctaat aataaaataa
     8341 cgtacatatt ttattattgc atacttaata acagaactat agcaaaaaat cccgtgtatc
     8401 aacacgggat tagattaagt ttcctcaatc actattcata acacaattat tataacaagt
     8461 aagtaaacaa ttgaaaagga catttattga aaacggttgt tttttactta aggaggaaat
     8521 ttagtgaaaa aattagttgc gttgtttttg gtcgcaggaa gtttgttgag tgggtgtggt
     8581 gctactacgt ctactactca aagcacaagt tcagctcagg cttccagcag cagtaccacg
     8641 atctccgaaa gtacggcaga ttcatcgaaa gaacaaattg aaaagaaaaa agaagaagag
     8701 aaacaaaaag cggaaaaagc tgcactagaa aaaaaagtga cagaagcgga atctgctttg
     8761 tcacaagctg aagcaaatcc tacaaaagaa aactatgcaa ctgcttcagc agctatccaa
     8821 gcgctacctg aaaacaaaca agagttgaca agccgtcttg ctgcaattga ttccacaatc
     8881 aaagcaaaag aagcagaaga agaacggaaa aagcaagaag aaattgcacg acaacaagca
     8941 gaacaagcgc aacaagaagc aatcgcacag caacaagcag aacaggcgag gcaagaagca
     9001 atcgcacagc aacaagcaga acaggcgcga cagcaagcag cagctgaaca ggcttctcag
     9061 caggcacaag ccgcagctcc tgagcaaaat aatgaacaaa ctgtctatgt cacaccgacc
     9121 ggttcaaaat accatacaca taaatgtgga aatggtacgt atacccctgc cactttaagc
     9181 gaagctcaag ctcgtggttt aaccccttgc tccaaatgtt atggaaacta attcaaaagt
     9241 tatactataa taataaaatt cttctgaaac ataaaaaaat agaagctggc gttccagata
     9301 gtaaaccaaa aatagcagtt tacacgtcca tttcgtcagc ttctctcttt tttcatttag
     9361 tctgttccct ctgctttttt ggacatcttc attcattctt tctcaatcaa atagtacacc
     9421 tctttttctt ttcgcagttt atatcttcct tttttcaatt tcattgaaaa ctgtttcgaa
     9481 tgtttatgtt ttacatggat tttaagcagg agctcctcat gttgcaagcg atagttcctg
     9541 ccttttaaat cagaaaatct cactagtccg tattcatcag aagctttcac aaatggaact
     9601 ttttctctag taatatagtg tttgccgttg agcgttttta cagaaaagac cattccttcg
     9661 attggtcgtc cgtttgtgtt ctttacataa aaagataaag gatagtttcg cttagcgatg
     9721 gccaaagaat ctaaataagc gatgagtagc caaactaagc cgattgatcc aagtagtata
     9781 ccgataaacc aaataaaaaa tttccatttt ttccattgat caattccttg gatcgctttt
     9841 tttgcctctt ttgcttgata aggaatacga tgccccgtca caagcagtcg atgtgtattg
     9901 accatataag gagtgcaggt aagcaaagtc acgagatctc tgcctttttg gatacccaaa
     9961 gaatctactt cgtcaggtaa gaccacttgg attttttcta cttgatacgc caatgtcttt
    10021 ccattgatct ggatgaaaaa ctggtctcct tttttcaact taggcaaatc tgtaaataat
    10081 tttgcttctg ggagtccacg atgcccagaa agaacggcat gggtgttttt cccgccagtc
    10141 ggataagaac ttccttccaa taatgacgtt cctttttgca aaaatatttc cgttgtctga
    10201 tcgaatatag gtaagctgac attgattttt gggatttcga tgactccaag catatgttcc
    10261 ataaaaaagg cattactagg taaatctttt aatgcttttg catcaactgc ttggttgaaa
    10321 ctgcctatcc ctggtgatac gttttgctct gccaactgtt ggtttttctt tgtcattttt
    10381 tcctgctgtt tttttatttc ctctgaattc ttattcgatg cttgcttttg ataatggatg
    10441 atcatttgct gggcaagaaa atcattcagt gaatcttcta caaaaggata agaaaagatc
    10501 ccgatcccaa cgactaaaat gattgccatg aagatgtcca gtattcttat tctgctttta
    10561 ttcatcatgt ccacctattt tctaatatgt atatgaagag gttgtgaaat cagcgccttg
    10621 acctgagtat tagcgaagca aacggcaaaa tagttcctcc tattttgccg tttgttgagc
    10681 gaataccaag agaccgacca cttgtcacaa cctttctccc catttgaatc actatcgttt
    10741 atttatcgta tgatttttgt ttccaatagt ttaagcttct gtttcttgat ggcgtttttt
    10801 gaaatagatc actgctcctc caactaaagc agtacctacc aagatgaata cgatgatccc
    10861 cataccacca gttgaaggca agattccttt aggttggtta tcgatcgttg tttcatcaga
    10921 agttgttgga tcatcatcta ctgtaaattc agtgtacgca gcttcattct taggtaatgc
    10981 gtagccttct ggtgcttttg tttcttgaag gcagtatgcc ccttgtttca gcccttcgat
    11041 tgaaaatttc ccttctgaat cagaaatcaa tttcacttct tcccagtcag aacctgtgac
    11101 ttcatctgac caagcatatg ggtattctcc tgaggcaagg tttgctattt ttttcattaa
    11161 tttaacagtt ggatcttttg ctcttagaat agaaaattct gcatcggcta atttttcttg
    11221 cgtgttcaca tcttgtttga tgaagtggaa atcaccgtag ttttggacat tttctacagt
    11281 aatcgtgtta tccgtagttg tattttcccg attgactaca ccgtttggat tcccaagatt
    11341 ggcttcatct gcgccatgga tgataccggt tgtttgttgc aattttccgt tttttactat
    11401 aaaagtagtt tctttttgtg gattggttaa ttgataacca tctggtgctt ttgtttcaac
    11461 taaagtataa ttgccgtcta ttaatccatt gacactgatg gatccttcag tatcagttgt
    11521 gaatgtcaac gctgactcag caggatcata gagagcgaca ccagtgtttt catcaaaacc
    11581 ggtcacgaat tgattctctg aatttttgat ctggaattgc gcccctgcta acttatctac
    11641 ccctgaaaag ttcccagctt tctggatttt gatattgctt tctttgatga catttttagc
    11701 atataggtga atcgtgtcta aaggtttgtc agggtctagg gtaagcttaa cacgatattt
    11761 ggcgacgttt cgacaccggg ctttggtgtt tctacaaaga cgtatacagc atctttccca
    11821 tcagatttac ctggaagagt caggttagct aatccttcac cagaagtcgt tacacttgcg
    11881 aagggtgtag cgtctgctgg aactgctgtg tctttacttg gatagtacgt agcagtgatg
    11941 tcatatacgt tgaattcaac gccgttcaac ggttcgctat tcggaaatgt caattccgtt
    12001 ccgttgttta tttgattttc tggtgctgaa gtgaatttca atttatgcaa attaaccgta
    12061 acattttctg gtgtaggtga tacggctgca gaaacctctg cagttcctag gccgagaacg
    12121 aaaggaagca gcatgatagc agttcctaaa aacgtccata tttttgtttt gatgtttttc
    12181 attttatttc cctcctattg tttccttttt gttgtttttt ataaaaccaa gctgtccctg
    12241 ttgaaaggac tagcaataac cctaaaattg agaaacctcc aagcatctct tcgcttgttt
    12301 ttggaaagct tcctccattt ttttcatttg atggaccatt tgtctgcatc tgaactggcg
    12361 tttttccatt attcgtcgga tttgcttttg gttcgttgat gatttccaat ggtataggat
    12421 gaagcggatc ataactgcct ttttcaactt caaagagaat ggttgattga ctcaatatat
    12481 atcctttagg cggtttaatc tccactagtt cgtaacttcc aaaagacaat ccatggacag
    12541 aaaatgttcc atctttactg gaagtaaaaa tcgttgctct tgaatcatct ttggctaccc
    12601 aatgatttat cccgttttct tgcgctaagt attggtcatt ttttttgact agaaattgag
    12661 catctgctag tttttgtttc gtttgccgat ccactttgac aaattgtttg cctcctgttt
    12721 ggatggcaag atgtgtttct actgtttgat tgtcagtcgt caaacgtaca tcgttatcaa
    12781 atgtcgtttt ttcactgttt tctttcaatg tcatttggta acggatcgtt aatttttttc
    12841 cagcaaacga actaagatct tttccagaat ctgataagac aaaaccatgt tttatttttt
    12901 gtgtgtgaaa tgtatgaatc ttgtctccac caatcaaaaa atcgatcgtt tctggttcta
    12961 gccataactg aggatcagct gtatctttga tcgtataggt tcctatctcg ttgatgttct
    13021 caggaattgt tacggtgatg agataaggga ctttatcccc atctgcaaaa tctgtctgct
    13081 tattctctac tgtttttgtt aatgtgagtg cagcaggtat tttttgttcg ctctttggat
    13141 acaagtggat ggtcgtcaat ttatgattag atgaatctgt cacaggaagc acaacgacaa
    13201 atggtgctga tttttctttt acttaatctg aagtctttat ttccgtaaat cggtaaacag
    13261 cgtcacgacc ttgctcatct ttgtccgatg cactaaaaga agcaatgccc tcttcctcgt
    13321 ctactgtttt tgtcacattt tctgccagta ttttttcact atcacttttt tgtgctagtt
    13381 ttctttgtgc gtcttccaca ctacttcctt ctgaccgcag cttgtaaaat tcatccgaga
    13441 catcatatat agcgaaagta acgccgttca acccttttac tccttgaaag ttatccggga
    13501 tatttattcc gtcgttttga ctgatacttg gcatcttatc gctttcgaac attcgattat
    13561 gcaaagtaaa tgtaataggt gattctctag ctgacacagt cggagaacct ataaaaaaga
    13621 ccagtaggat aaaaaagaga acagcaaata tatccacacg tacatttttt gtttttttca
    13681 tcgctgttca cctgcttttt tcttacgatg gataaaataa aagaagccag aaaaaataaa
    13741 gatcagtcct aaaaagacaa agggcagtag acctatccca cctgtcgaag gaagcaagag
    13801 agtcggattg atcgtcaact tagcggtatc tgttgcgata atcgtataat tattgtttac
    13861 acttccttcg cctaaactaa tcgttactat ttgtgatcca atatctgtcc ggctgttaac
    13921 tgttagggta taatccaatg attcgcctaa gacaacaccg gtaacgtgga gatttccaac
    13981 cgaaatcgag tgactttggg catcataatt aaaggcagcg tcatcgacag taatcactgc
    14041 gttagcttta tagatggtat aagttcctga tgtgttggct atatcagtaa atgacaactt
    14101 gggatttgct gctttgactt tgtctattcc gctattcgtt agtttaattg tatagctgcc
    14161 agcattaacc atattttttg ctgattgtgc atctgctgtg taatccatac tgctaagtgc
    14221 cacttgtact ggagtaagcg aactagtgac accctctgct agcttgacat ggattgacgg
    14281 gacacctgct tttccatcat atgtcttact gccactgagc tctaccgcac cgctgatttg
    14341 cttaatcgta tagacatcag atgtctgcac gatagtaaat aaatagtttg ttctggcagc
    14401 tagtttagct agtccgcttt ttgtcaattg ccaagacgta taggttccaa tttcagtagg
    14461 cgcagttact tcaactccct tttcattcat cgctttgaaa tcagttggat tccatgtgat
    14521 ttgatcaata ctgagatcat tgtttaaaag ggatgttgat tctgttttat cattaaaggc
    14581 atatttaacg atcggtacaa cagaaagacc atcatagtac ttactgccat ttgcattgat
    14641 tgatactgtt gcatttgtct tataatatag gatgacttca gaaatctgtt ttccatttgc
    14701 gtcctttacg attacatttc catttgtatc taaactagct aaaacactca ttgctgattg
    14761 gttctttgtt tctatcgctg aaacagctgt aaaggtatat ccgttgatag taggcgtatt
    14821 agtcgtcagg tcttgtgcag cacttccgta agtaagattc attattttag aaggagcaat
    14881 catctgtcca aaatagtctt gatacttaat agtgattggt gtttgtttgc ctgtataggt
    14941 caccgtatcg acgttacttt ctagggctgt gaaagaaccg tttgtttgtg caaaagaata
    15001 gcccgttact gctgttggag tgataaccac tttgtcaccc acatggattc cagataatgt
    15061 agtcccgtac gttccgattt ttgctgctcc accattgact gtataagaaa aagttcctgt
    15121 ccgattcgca ttgacctgaa ccgttgctgc ttgataggtt ggaaaatttg aaacatttcc
    15181 cttaccatca acgatctgcc catttttgat cgagtacccc gtgaatggaa tatcatttgc
    15241 taactgtata ccgattgaaa aagtactcat acctcctccg gcaggaagcc ctccccatgt
    15301 tgagggtgta aaagaataac ttttatccgc attgggtgta actgaatcga tcgtatttcc
    15361 agcggtagcc acccccatat agatactttt tgggaatgtg atagtagtac catttactgt
    15421 ggagccaata aacagattat ggatatctgg acggttatca ataaaagcga ttgctttggt
    15481 tacgccttgt aacgcagttt tatccgcact catcgatccg ttaaccgcaa caatgactcc
    15541 atctttggca tatatcactg tatatccatc tggtatggta tgtccgttga aattcgcagt
    15601 ggccgcaaca gtactaaatg tctggcttct acctgtttct gaataagctt tctcccctgc
    15661 tgcttttgct gctgtgattt ctttttctgt cggatcaatc agttgagtcg aggatgtggt
    15721 tgaggttgtc tcgttgttgc tagactgatt ggtgctttct atggactgta tttcagaata
    15781 gggtggacta tttgtctcct ctgtcgtttg gttagcaaaa tttgacgttt ctgtataaac
    15841 gtttacataa atacttgata agctccctaa gaaagtaaaa atcaagatga tcgaaatcat
    15901 aatgggatgt aagtattttc ttttagatac agctttgagt ctagaaacaa aatgtttttg
    15961 acatatacgt tggattttat tttgagtttt cttaatcatt ttcatccctc ctctcaataa
    16021 aaaatcatca aataatcctt tacacgttat tctaaattta atttttatta ttttattgat
    16081 gtatagaaag tttggggctt tttttctctt tttattctaa ggttatttta gtcttgtcct
    16141 ttaatacaaa gattttattt ttaaataaaa aatactcttt ttttacgatt attgaaaaaa
    16201 aaagataaaa cttgattaat tgaagtattg cttaaatttg gaagc
//
LOCUS       DAFTHM010000059        16087 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFTHM010000059 DAFTHM010000000
VERSION     DAFTHM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.059"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            138..1475
                     /locus_tag="L7C88_001824"
     CDS             138..1475
                     /locus_tag="L7C88_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBP9558641.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            1523..3652
                     /locus_tag="L7C88_001825"
     CDS             1523..3652
                     /locus_tag="L7C88_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBP9558642.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3627..4316
                     /locus_tag="L7C88_001826"
     CDS             3627..4316
                     /locus_tag="L7C88_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558643.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(4724..5410)
                     /locus_tag="L7C88_001827"
                     /pseudo
     CDS             complement(4724..5410)
                     /locus_tag="L7C88_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(5546..5740)
                     /locus_tag="L7C88_001828"
     CDS             complement(5546..5740)
                     /locus_tag="L7C88_001828"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558644.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5790..6230)
                     /locus_tag="L7C88_001829"
     CDS             complement(5790..6230)
                     /locus_tag="L7C88_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBP9558645.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(6234..7079)
                     /locus_tag="L7C88_001830"
     CDS             complement(6234..7079)
                     /locus_tag="L7C88_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBP9558646.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            7228..8646
                     /gene="pepV"
                     /locus_tag="L7C88_001831"
     CDS             7228..8646
                     /gene="pepV"
                     /locus_tag="L7C88_001831"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBP9558647.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(8703..9650)
                     /locus_tag="L7C88_001832"
     CDS             complement(8703..9650)
                     /locus_tag="L7C88_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBP9558648.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(9873..10223)
                     /locus_tag="L7C88_001833"
     CDS             complement(9873..10223)
                     /locus_tag="L7C88_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBP9558649.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            10423..11502
                     /gene="pepA"
                     /locus_tag="L7C88_001834"
     CDS             10423..11502
                     /gene="pepA"
                     /locus_tag="L7C88_001834"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBP9558650.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            11646..11966
                     /locus_tag="L7C88_001835"
     CDS             11646..11966
                     /locus_tag="L7C88_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBP9558651.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            11988..12452
                     /locus_tag="L7C88_001836"
     CDS             11988..12452
                     /locus_tag="L7C88_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBP9558652.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            12657..13262
                     /locus_tag="L7C88_001837"
     CDS             12657..13262
                     /locus_tag="L7C88_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBP9558653.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(13301..14590)
                     /locus_tag="L7C88_001838"
     CDS             complement(13301..14590)
                     /locus_tag="L7C88_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBP9558654.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            15018..15497
                     /gene="rlmH"
                     /locus_tag="L7C88_001839"
     CDS             15018..15497
                     /gene="rlmH"
                     /locus_tag="L7C88_001839"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBP9558655.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            15700..16087
                     /locus_tag="L7C88_001840"
                     /pseudo
     CDS             15700..16087
                     /locus_tag="L7C88_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336126.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
BASE COUNT         5078 a         2950 c         3279 g         4780 t
ORIGIN      
        1 cataattaag gttttttaat tgaaaactga acatttatgg tcacccttta atgaaagcgc
       61 taactacata agttagaatg agtttgactg atatattagt ttgcttatca gaaaaacaaa
      121 atggacggag gaataacatg agtgatatta ttattggtat tttgttagtt atctcattct
      181 ttttcatggt ctggtactgt gtaaaaggct acaacttgat ggtcggcttt gccatcatgg
      241 ctactgtatg gatgggatta gcgctagtcg gaaacacgtt ttcaccaaac ccggcgatgg
      301 aagggcaagg agtaattgat gtgttgacgc atatctatac gacggggcca gctgagtacg
      361 ccaaatcgat cttggtaaat gtcttctttg gtgccttttt cgggcgtgtt ctagtagata
      421 gcggaatcgc agctaccctg attcgaaagg tagttgaact tggaggggac aagccaagaa
      481 tcacgatgag cttactatgt attgtaaccg ctgttatatt catgtcgatg acaggaatcg
      541 gaccagtgat ttctattgca gttattgtgt tgccaatctt gatgtcatta ggtatttcag
      601 taccggttgc actgttctca tttatgggct cgattatggc tggaatcttt gctaatatcg
      661 tcaatttcaa acaatatcaa acgatttatg ctggtttcaa tccagcggct gaaagctata
      721 cttataatga ctatttccaa attggtatga ttgggatgat tgtaagctta gttgtggtac
      781 taacggtcgc taatatatca atgaacaaaa agaaacgcta tgcaatggca gcaaacgtac
      841 cagctgaagg tggcgacgca ccaatgatct catggttagc cgtattatta ccagttttag
      901 gggtcgttct tttagatctt ccaatcatct taggttttat tctagcaggt atctgggcat
      961 tgctgtttac tggaaaattg cgcggaggtt ataaagaaat ctgtcgtcag tttgcgaaat
     1021 tatttacaga tggcgcagta gatgttgcgc caatggttgg tttcttgatg accttagcga
     1081 tgttcaataa ttcagctgcg tatgcttctc cttatttttc agctattttt ggagattgga
     1141 taccgcaatc accattagtc ttggcaatcg tatttgctat attgacacca ctaggatttt
     1201 tccgcggtcc aatgaatcta gtcggttcag gctcagctat tttagctgtc gtattagctg
     1261 ttaatccaac gatgtcgcca gcctttttgt tcccgttatt tgcaatcaca acgattgctc
     1321 ctcagcattt agatattaca caatcttggg ttgcttgggg attaggttat acaaaagtaa
     1381 cttctcgaga atatatgaag aaatccatcc caactggttg gatcatcgga gcgatcttat
     1441 gcctgatcac gttcttattg tacgggaacg cctagtaaac aaaacgtcga taaaaacgat
     1501 tagatgaatg gaggaaaaga aaatgaaacg ttttgtgcga atgggaattg atgttggcgg
     1561 tacacatacg aaagcagtcg caatcgataa tgcgacgcac gaaatcatcg gaaaatcttc
     1621 agtgaaaaca acccacgatg atgtccgtgg agtagccgca ggtgtcgttc agtcttttca
     1681 aaattgtttg ctggaaaata atatcagtcc agaagatgtt gtgtttgttg cacattctac
     1741 cacacaagcg actaatgcac tgattgaagg agacgtagca aaagtcggcg taatcgggat
     1801 ggcaaaaggt ggattagaag gttttttagc aaaacgacaa actagattga acgatatcga
     1861 tttagggaat aagaaaaaaa tagagattgt caatgcattc ttacctgtca aacacttaaa
     1921 tgtagaccgt gtttcagaaa cgatttcttc tttagaaaga gaaagagcgg aggtcttggt
     1981 ttcttctatg gcatttggag tagataatgg ggaaccagaa cgagttgttt atgaagcagc
     2041 atcggtaaaa tcgatcccta caacgatggc ttctgacatc acaaaattat atggattgac
     2101 aagaagaact cggacagcag caatcaatgc atctatttta ccaaaaatgc tagatacggc
     2161 aacctctaca gaagattccg tacgagaagc aggggtcaat gtttctttga tgattatgcg
     2221 cggagacggc ggagtaatgg aaatcaatga aatgaaaaaa cgacctgttt taaccatgct
     2281 ttccggtcca gcagcatcag tcatgggctc tttgatgtac ttgagagcgt ctaatggtgt
     2341 ttattttgaa gtaggcggaa caacaaccaa tatcggggtc attaaaaatg gacgtccagc
     2401 aatcgattat tcaattgtag gtggccaccc aacatatatc tcttcattag atgttcgggt
     2461 tctaggtgtg gcaggcggtt cgatggtacg ggctaatcag tcaggaatca tcgatgtcgg
     2521 tccacgttct gcacatattg ccggtctaga ttatgcagta tttacggaga cagaaaaaat
     2581 caaaggtcct aaggttgaat ttttctctcc taaagaagga gaccctgctg attacgtcaa
     2641 ggtagtgatg gaagacggag aagaagtgac tattacaaat acatgtgcag ccaatgtcct
     2701 tggattagtg caagaagaac atttttctta tggaaatgtc ccatctgcac gaaaagccat
     2761 ccaagcatta gctgattatt gtcatacgac ggttgaagac atcgcagaac agatcatgga
     2821 aaaatcctat gctaagattg aaccggtgat tttagaattg gcagacaagt atcacttgga
     2881 gaaagatcag atttctcttg taggtgtagg gggcggcgct gcctcattga ttacttactt
     2941 tagtaataaa atgggtgtga aatattcgat tcctgaaaac gccgaagtga tttcttctat
     3001 tggtgtagca cttgcaatgg tccgagatgt tgtagaacgt atcatccctt cgccaagtaa
     3061 agaagatata cgatcgttga aaaatgaagc gatgaataaa gcgattgaat caggcgctac
     3121 accagaatcg atcgaagtcc acgtagaaat cgatccacag acttcaaaag taacggctat
     3181 cgctactggt tctacggaag tgaaagcaac cgatctaacc aaggagatca caacagaaga
     3241 agcactagag cttgctgcag aggatatgcg attaaataaa aatgaagttt gcttattgga
     3301 aaatacacct ttcttttatg tatgcggcga acagaatcgt tcaaaaaatg ctggaagtct
     3361 tcggatcatc gatcaaaaag gatttatcaa ggtccaacgt ggacatgctt catgtatgaa
     3421 aacaactgca gccaattata tgacagctgt cgaacaactt tgggaagata tggcagttta
     3481 tcaaactgaa ttgattgccc gaccagaatt ttatctctgc ttaggagcaa gagtctctga
     3541 ttttacagcg acggatctgg aacaactaca gcttttgatg gatctggaag tatctactat
     3601 ggaaccggag gaagaagtga tcgtcgttgc cggaaatatc aaacaaacat aagttagaag
     3661 agttactaaa cgaattacaa cagatccccg aagaaatttg gggattctac cagtttcggc
     3721 gagatttatt ttggaaaaag attcctttgt ccaagcagaa aattcttata caacaatcaa
     3781 tcgattgtgg tatcgaaacg gcatgtagca tcaaaaaaaa gtaccctttt gccgatgtag
     3841 gagaaatttg tgaacaaatg gctgttccaa tcgtttcctg tgaatcagag caaataaacg
     3901 aacgaatcac ttttgcaact tatgcagaag atgaagggat tcgattgatg acggagccgt
     3961 tagaaaaatt aaaatgttca ggactagctt cgatctctaa agaaacagcg caagctttga
     4021 ttattggaca tgaactattt caccacatcg aagcttctgt taagggaatt tatacgcaaa
     4081 gcgaaaaaat tgtgctgtgg cggttgcctt tttatacaca tcaatcaaac attcgtgcat
     4141 tgagcgagat agcagcgatg agtttttcaa aagagatgaa tcaaagcgat ttttcgcctt
     4201 atgtattaga ggcagtctta ctttggccat ataatgaaat tcgtagccaa gggatcttag
     4261 aagaaataaa aaaaatagaa aaaagatgta cggagtatga tttagattac aaataaagag
     4321 actgtgacaa aagtcgtgtc acagtccttt ttttccgaat aaacggtgtt ctcctgtcaa
     4381 ctcctcggtc acaagtcaaa atattcaaca aacatgagaa gctgtttttt gaaattgttc
     4441 cttgtgactc ggagatgaac ggcaggctca cgacctcttg gaaaacggtg ttcaaaagct
     4501 tgcatctgcg gtaataagtc cagccaagtt aaaaacataa gaagctattt ttacttggct
     4561 gttcttatta cttgatgcag ggcagctttt tcacaacctc tcaataaacg gtgtgcaatc
     4621 agctgaccct cggtattagc tcaaaaaaaa cggcaaaata tgaggaacta ttttgccgtt
     4681 tctttctcta atactcaggt caaaacgctg attccaaaac ctcttatttg atgggtctgt
     4741 cctgaatatc ttcaaaataa tcggggtaat tatgaatcac gtattcttgc tcctcgataa
     4801 tcatatgtaa atgcatcgtg caaagaaatc cgacttcatc aaagttatga tcaatcattg
     4861 attgaagcat tgtctgatgt tcatctaata ctcgacccca gtctaattct gaaatcgtca
     4921 aacgtaacca tctgaaacgg ttcaagtgcg tactataact ttctagccaa tcccaaattt
     4981 ctcgttttcc agcaatttca taacaagttc ggtgaaaatc agtatccaaa tcaaaaaaag
     5041 cttttttatt ttgagcgatt actgcctgat cggtttgttc tagtattttt tctagtttag
     5101 cttgatcttg cttggtcatt ttcgcactgc attcttgcag gatcggtttt tccaactttt
     5161 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
     5221 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
     5281 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
     5341 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tacaaattat
     5401 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
     5461 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
     5521 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttggatc ggtttgacac
     5581 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
     5641 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
     5701 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
     5761 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
     5821 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
     5881 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
     5941 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
     6001 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
     6061 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
     6121 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
     6181 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
     6241 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
     6301 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
     6361 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
     6421 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
     6481 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
     6541 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
     6601 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
     6661 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
     6721 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
     6781 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
     6841 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
     6901 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
     6961 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
     7021 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
     7081 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
     7141 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
     7201 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
     7261 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
     7321 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
     7381 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
     7441 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
     7501 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
     7561 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
     7621 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
     7681 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
     7741 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
     7801 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
     7861 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
     7921 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
     7981 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
     8041 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
     8101 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
     8161 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
     8221 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
     8281 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
     8341 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
     8401 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
     8461 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
     8521 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
     8581 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
     8641 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
     8701 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
     8761 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
     8821 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
     8881 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
     8941 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
     9001 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
     9061 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
     9121 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
     9181 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
     9241 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
     9301 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
     9361 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
     9421 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
     9481 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
     9541 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
     9601 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
     9661 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
     9721 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
     9781 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
     9841 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
     9901 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
     9961 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    10021 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    10081 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    10141 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    10201 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    10261 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    10321 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    10381 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    10441 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    10501 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    10561 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    10621 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    10681 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    10741 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    10801 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    10861 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    10921 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    10981 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    11041 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    11101 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    11161 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    11221 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    11281 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    11341 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    11401 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    11461 ttggataaat caacagtaaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    11521 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    11581 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    11641 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    11701 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    11761 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    11821 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    11881 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    11941 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    12001 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    12061 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    12121 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    12181 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    12241 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    12301 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    12361 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    12421 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    12481 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    12541 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    12601 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    12661 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    12721 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    12781 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    12841 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    12901 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    12961 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    13021 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    13081 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    13141 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    13201 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    13261 aaagaggttg tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat
    13321 tttgttttaa tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc
    13381 cttcatagta agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa
    13441 gttctacacc agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca
    13501 atccagcttt ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta
    13561 cagatgaagg aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga
    13621 ccattgtgat acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga
    13681 tattcactac atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag
    13741 tagattcaga agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat
    13801 taactaaagg accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga
    13861 tattgactgt ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga
    13921 ttcctgaagt gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag
    13981 gctcaccaac cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg
    14041 aattgatctt caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta
    14101 ccttcgtacc gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat
    14161 tcgtgactac ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat
    14221 aagcttccaa attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc
    14281 caaaaccgct tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa
    14341 ctttatctac cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg
    14401 tttcaccggc agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca
    14461 tcgctgcata aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca
    14521 gacctaactt acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt
    14581 ttctatccat gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat
    14641 ttgttgactt tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc
    14701 attgttttca gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc
    14761 ggataggatt ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa
    14821 attcttataa aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt
    14881 tttctgtgga taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa
    14941 atagccaaaa taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag
    15001 accaaaggag agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat
    15061 acctgatcca aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat
    15121 tgatcgaagt tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag
    15181 taaaagaaaa agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg
    15241 ccttagcaat tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat
    15301 taggtatcca aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg
    15361 aagccgtcat gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc
    15421 aattgatgcg tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg
    15481 ctccatacca caaataatga tattttttaa gagaaaaaat tatccctatt ttaaataata
    15541 gcaataggta gtggtaggga gaaatttata aataactttt ttatttgctt tggtagccaa
    15601 gtaagttgca aaagaaaaat agatactgtt aaaaagataa tgtagacata gaaacaaata
    15661 cgtaaaattt tagttagaat aatggcaagg agaaaaaaca tgatagatga aaaaaagtgt
    15721 ttaaaaaatc tattagagga tatggatgat attgaagaaa actatctaaa tggactggga
    15781 aaacaaatat atttcagata cttaagctat ctaaaaatga aataagacat agtaattttt
    15841 tagctttttt gtttgctcca aatgaaaccc acaatttatc tgatgagttt tttaaaatgt
    15901 ttttgaaaag gtatatagat tctaatgatg ataccaaagc tgctatcaat tattttgatg
    15961 ctttacttaa tagctatgaa gatttaattg tttacagaga aaataagaat attgatattt
    16021 tattggtatc ggaaaaaaat aaaatagtgg tgtgcatcga aaataaaatt ctgtcttcgg
    16081 agtctgg
//
LOCUS       DAFTHM010000060        15204 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFTHM010000060 DAFTHM010000000
VERSION     DAFTHM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.060"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(178..687)
                     /locus_tag="L7C88_001841"
     CDS             complement(178..687)
                     /locus_tag="L7C88_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558656.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(783..1163)
                     /locus_tag="L7C88_001842"
     CDS             complement(783..1163)
                     /locus_tag="L7C88_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBP9558657.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            1493..2242
                     /locus_tag="L7C88_001843"
     CDS             1493..2242
                     /locus_tag="L7C88_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBP9558658.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(2426..3703)
                     /locus_tag="L7C88_001844"
     CDS             complement(2426..3703)
                     /locus_tag="L7C88_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558659.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(3782..4426)
                     /gene="pcp"
                     /locus_tag="L7C88_001845"
     CDS             complement(3782..4426)
                     /gene="pcp"
                     /locus_tag="L7C88_001845"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBP9558660.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(4625..5569)
                     /locus_tag="L7C88_001846"
     CDS             complement(4625..5569)
                     /locus_tag="L7C88_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBP9558661.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(5571..6257)
                     /locus_tag="L7C88_001847"
     CDS             complement(5571..6257)
                     /locus_tag="L7C88_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBP9558662.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            6731..7051
                     /locus_tag="L7C88_001848"
     CDS             6731..7051
                     /locus_tag="L7C88_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBP9558663.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            7205..8110
                     /locus_tag="L7C88_001849"
     CDS             7205..8110
                     /locus_tag="L7C88_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9558664.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            8107..8880
                     /locus_tag="L7C88_001850"
     CDS             8107..8880
                     /locus_tag="L7C88_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBP9558665.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(9061..10485)
                     /locus_tag="L7C88_001851"
     CDS             complement(9061..10485)
                     /locus_tag="L7C88_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9558666.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            10696..11142
                     /gene="nrdI"
                     /locus_tag="L7C88_001852"
     CDS             10696..11142
                     /gene="nrdI"
                     /locus_tag="L7C88_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBP9558667.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(11207..13189)
                     /locus_tag="L7C88_001853"
     CDS             complement(11207..13189)
                     /locus_tag="L7C88_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBP9558668.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(13203..14099)
                     /gene="murQ"
                     /locus_tag="L7C88_001854"
     CDS             complement(13203..14099)
                     /gene="murQ"
                     /locus_tag="L7C88_001854"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBP9558669.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(14102..15163)
                     /locus_tag="L7C88_001855"
     CDS             complement(14102..15163)
                     /locus_tag="L7C88_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBP9558670.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
BASE COUNT         4417 a         3214 c         2672 g         4901 t
ORIGIN      
        1 gggcagacga ctggcatttc tttatcatta tgttcgacta cattattgac ttcttcgtat
       61 gcaaattttt ttccgcaatt agggcatttc attttttcca tgttatctca acttcctttc
      121 atctttactc tcttagctta ctcttatatt gtaaaaaaga gaagcaatat ccttcttcta
      181 tgcagatatc catacctgac ggtcctgttc tccatctatt aatcggactt tataataagg
      241 acgttcatct ttgactagaa gtgtccactc tttcactttt gcttttttcc cgtagtagct
      301 gactgcttcc ttcatcgctg cttgcggttg tttgaactct tccgtttttt ctatatcaaa
      361 aagatgttct gcggcctttt ccgtgtcatt tcgtacggtt gttttcccag tggatggatt
      421 gactgctatg acttgtcctt cacaaaaaaa ctggtattca tatgttgcat tcgtaggatt
      481 ctccaaatct ttttcaactg caaaatgaat agcagatatg ttatgttctt ttgtttcgtt
      541 ttttacgatt gctgctgctt ttttcaatga gatccgatat tcctggtcac taatatcatc
      601 catgtgaaaa gcggcattga gcagtcccgt cataccggta atccctatta cgatgagggc
      661 agcaacacca aacatcattt ttttcattct tcattctcct gtttcttttt tttaaagaat
      721 atcaagaaat gaacgaatga aaaatcgaat gaaacgaaaa aaaagtgaca attttgttat
      781 ctttattcgt gcagttctaa tggcaatccg tctggatcaa agaaaaacgt catttttttt
      841 cctgtaaagg tatcttctct aatcggttct gattcgatcc ctaaggactg caattctgca
      901 attgtttctt caatatcgtc tactttgaaa gcaagatgac gcaagccaca agcttctgga
      961 tagtttggtc gttgtggcgc attagcaatt ccaaaaatct ccaattcagc acttcctagt
     1021 ttcagatcta atttatagtc atctcgttct ttgcggtaat tttctctgat tacttcaaat
     1081 cctaatttat taacataaaa atcacgtgat ttctgataat ctgaaacaat gatggctata
     1141 tgatggatcg ttgtaaggtt catatgagca ctcctattct tcgtttaagc tcggatctat
     1201 attaatctcc agttccattg taaatgtgtc agattgaaaa aaatagctgt ttttcctttt
     1261 tataagaaaa aaggcaaaaa aaacagaaag taggtcctcc aagacactct tcctgttccc
     1321 aatataataa atgaaagtaa gaaattatat tttcaagaaa acaaacagaa aattatcata
     1381 acacaaatta tttataattg aaagactagt tttttttcaa gaaaagcata caatagattg
     1441 tgttagtaaa tacagaacac actacattta gtgtcttaag gagtcctcat acatgaagtc
     1501 atattttcag tttttagctc atcagctaaa aggctggccg caacaaaatt attatctttt
     1561 ctttttcagt cttggctgcc aggtcatgac tcttgtcaat agtcccatca cttggctgtc
     1621 cgttattaca tttatcggta ccacgcttgg tgtattgtgt attttatcca tcaatgcggc
     1681 aaaatcagtc aacggtattt taggtatttt gtctgcgatt tgttttatta tcgttgggtt
     1741 ttcagcaaag aactatttaa gtatcggtga acagattgct tatatgatca cattggatat
     1801 ccccgtattg ttaagtaaag aatggaatca taatatggct tcaaaaatcc gaaaattcac
     1861 tggaaaaagc tggtttatcg caatcatcag tactttcctt gtctatcttg tttcaggatt
     1921 cctgattggt cgttatacag atgatcctcg gccgtgggta gatgccattg ctttttctat
     1981 tagcttgact gctggtatca tcagtttctt gcgttacaac aaccaatatt actggtggtt
     2041 agcttcaggg cttgctcaaa tggtcctttg gtatatttca tttacgcatg gatctgcaag
     2101 tttggcgatg ttcgtgaaca gctctgttta cttgctgaat gatgtccttg catttaccgt
     2161 ttcaccttgg tataaccaaa aagaacgtga acgtatgcaa aaaatggaag aagaatacta
     2221 caacgcacaa caacacgcat aaaaaaactg agcgtgggac aaaagtaaag aacacttttg
     2281 tctcacgctc taaacacgta taaacggcgg aatcagaagc aactccttcg gaaataagct
     2341 gaaattcaca aaaatttgaa aagcaatttt cgtgaatttc ttcttatttc ttggagttaa
     2401 acgcttctgt cccagcctct attttttata gtaattcctt cagatacttt cttgcctcat
     2461 cattgaaacg cagtgattct tctaacttct gataatattc caacgcttgt ttctgagctt
     2521 cagtaaaacg ataatgtttt cctttccatt tgtcgattgt ctcttgcaca tttccagatt
     2581 ggatatcttt cactactagt tgccattttt cttttgagac tgtacggtct ttcttatcag
     2641 cagattgtat agcttctcgt tctttacgca atacttttaa aaaaccattt ctgactatcc
     2701 gaggaatgct gtcgaagaac ccttctgtaa aaccatagcg acaatattgc ttccaaataa
     2761 atagatagat ttttggttgg atgaatcgtt ggtttttcgc aaaatattcc atctgagcag
     2821 tgacttctgg tgttcgttga cgttttgtct ttctcaacac ggaaataaat gtttcaaaat
     2881 aagcattagg atgtactggc acttcttcat atacgatgga ttgccaatct ttacgtaaaa
     2941 atgcgcgata gttgatcaag aattcttcta catcctttac taattcttct gcaaagtcgt
     3001 caaatagttc tttttttatc tgtcgctttt ttgactgccc attgatgtgt tcacttattt
     3061 tcttgatttc attttccaat gcttgataat ccgctatgta aatcggcatt tctacttggc
     3121 gaaattctgc gagccgctga gctaatttta tatccggtaa atatggctgt ttcatccgac
     3181 gattttggta caagacaaaa cagtattttt gccatagtcc ttcaggaaaa tcgatattct
     3241 tctgcttaag ccataataat tcgtctaagg ccagatcaac ttttgtcatt ccctgatgga
     3301 tcgaagctgc cactgtcgga gagacatgca ggtgatcggc aaagtggttg atgcctagtt
     3361 ttaggatctt tccggttttt ggcgatttaa cgatgtattg cacttttaat tctctaccac
     3421 actcacaata caatttttgc tggcttcgtt ttgttcgaaa aaacggattg atcttgaagt
     3481 cagaaaacac ccaatctgtt gcagctaaat aatgttcttc cataaaacga gagctgatta
     3541 gatatcggcg gtgcttatcg actagttccc gctgtttttt cgttaatttt gcatagatct
     3601 cccaacgttg actgcttgtg tattgtttag aaattttgat gggatagctt ttgctgattt
     3661 cttttggaaa ccattcttca aagacggatt gccattcttc cacggctgtt tctttccttt
     3721 ctaattacaa aaagctggct actaacataa cgttagcaac cagccagtgt ttcttgctaa
     3781 attagtgagt tgttccggca tttccggaaa tatcttcttt attttctact gctgcttcaa
     3841 ctgcataagt caaagaagaa gcaatgtctt ctaaagacat agaaggcgta cccactggac
     3901 gatcgatcac ttgatcgggt gagaatggca cgtggatgaa cccacctcga attgccggga
     3961 attgtgtttc gatcaaatga agcaaacgat acatgatatc attgcagaca aatgttcctg
     4021 ctgtataaga gatgtacgct ggtagaccat gatcttgtac attttttgtc attgctttga
     4081 ttggcaatga ggtaaagtaa gcggctggac cgttttcttc taaagccgta tcgaatggct
     4141 gatttccttc attatcaggg attcttgctt ctgctagatt gattgcgaca cgttcgaacg
     4201 agactgctga ccgcccacct gcttgtccga cacagatcac gacatctggt tggtgctgtt
     4261 ggatggcttc tttgactact tgactgcttt tttcgaatac ggtcggtact tccactttga
     4321 tgatttcagc accgctgatt tcatctggca ttttttttac tgcttcatag gctggattca
     4381 ctttgtcccc accaaatgga tcaaaacctg ttactagtac tttcatctgt tgttcctccg
     4441 tccgattgat ttaacatatg gttatctttt atcataccat tttccttgaa cagcgtaaat
     4501 aaaggaaaca atagtttaaa taacataaca gatcaaactt aatatattct tataaaaaaa
     4561 tagtgttcca ctacaatgtt agaagaggtt gcgacaatta ttctgtcaca acccctctct
     4621 tctattattt aaatagaatc atataagcaa tttggaaaac tagcataaat aacgcaataa
     4681 acaactggtt tttgatcact ccgtatttgt ctttcatctc cagcatcgct acaggcacga
     4741 tattgaagtt agcagccatc ggtgtcagca gggtcccaca aaaaccgcaa gtcaatgcaa
     4801 ccattcctat taacgctgga ttcgctccat gactaaatac gaatggtgca ccgatcccaa
     4861 ccgtcatcac ggtgatggcc gcaaatgcat tccccatgat taccgtaaat atcaccatgc
     4921 caagagcgta aatgatgatg ccgatgttca catttccttc tggaacgatc gtacctactg
     4981 cattggaaat cactgtccca actccagcgc ttgtaaatac cgcacctaga gaagctaaaa
     5041 gcattggcaa catgcttaac ggccctactg tgcccagcat atctgctgca tcatctaaaa
     5101 atgtacttgg tcgattatct cgagaaaaga acatcaagat tagcatggct gcaaaaacac
     5161 cgacgcccac gccgactaaa gcacctaaat tggtaaatag agcaaacaag atcgcaaaga
     5221 caccgatact caaagctgga ataaaaattt tcattcctag tttgtctgac attttttcca
     5281 tatattcttt tgatggaagc cggctttctc ctttgctgac tttcttagca attgctggta
     5341 tggtcatcgc aaagatcaag ccaccgttca cgattgccgg aagccatctt cctcctgcaa
     5401 taactacccc taagaccgtc cagaaaaagg ctgacccata acgatgagga ttggttttat
     5461 ctgttaaatt tcttactcca gtgtaaatca atacgagtcc catcacgata taaaggatct
     5521 ccagtaattt atcgcctaat aaaatatcag gatttgtaaa aaagtccatc ttattgcccc
     5581 tttcctggat aatatttctt cgctaatttc ttttctttaa gatagaagta gacacttgcc
     5641 acaactaaag ccgtgatagc cactggaact tccactaaag caagctgtcc caatgttacg
     5701 tcatatccta gatctttcag tgttgattgg actagcaacg cccctgctcc tccgatgaat
     5761 agtacttggc caaagaacca gcagacattt tccatagctg aagccatacc ttttagttct
     5821 tcttcatgct taggatggac ttctaaccct tttgattcga tggtccccaa tgccatcggt
     5881 aaaatgattg gacgaacaaa tccagcaact ccaccaaaac tcacgttaaa agccgcaaag
     5941 atcattcgaa agatcccata aatatctaca atcataccag cagatacttt cttgaatcgc
     6001 ttgatcaagg aagccgctga ttctttcaga ccatttcttt caagcgttcc tgttgccaac
     6061 ataatgatga taaaaatcgc catcccgcga ttgtttacaa aacttgtacc taaaagttct
     6121 aacattcctt gaatgccaag accgccagtc aaagctgtaa caactaaagc aaccattacg
     6181 atcaatatcg agtctaattt aaatgcaaac ccgagaataa caatcaagac gcctaaaagg
     6241 ctaagataat tttccatata ttttcctcca taaaatgaca atattttttt aattataaag
     6301 caaaacacat aaaaaatata gttgttttct cacgaaatag acactatttt taaatatttt
     6361 tcgttatttt tttatcacaa aaattatctt acttattgta aggtaaagct ttttttaatt
     6421 tattgcccga taatatatag aaataaggtc tagttactgt tttttttaaa tgattaataa
     6481 ataacaactt ctttctatga aattgcaaag cattcatctt cttttccgct aacgatatat
     6541 ccgtcagtgc ttggtacact ttactaaaaa gtatgagatt gccgatatct ggataggtgt
     6601 gctatactac agaaaaagat atacaatctg ccaccgggta ggataaagag gatgatcatt
     6661 ccattaggtc tttgaaggga tgattttcct ctttttgtgt atttttttat agttaaggag
     6721 gaatgtaagt atggcatgga tggaattaat catagcagga attttggaag tattctggtc
     6781 aacgatgatg aaatggagtg atggtttttc taaaatcaat tattcttttt acacagtgat
     6841 tggcatgatt gctagttttt actttttgtc aaaggcaatc aaaagtttgc cgatgagtct
     6901 ctcttatcct atctggacag ggattggcgc agttggttcg gtcataattg gtgtggtctt
     6961 gtttcatgat aagctgaatc tttccacttg gttctttgtg gggatgctac tcatcagtat
     7021 cattggcatc aagattacta gcggccacta gacacttgga ataagtactg atcagaaaaa
     7081 ataagccttt ttatttaata ttcaattttt ttatgaaaaa ataagaaata agtccaatga
     7141 cctagcgact tctccactca tcaggtgtat gcttgtacta tctatagaaa aggagtgaat
     7201 atttttgaaa agtctttcgg tccaagaatt atccaagaac tttggtcaca aacaagccct
     7261 cagcgatgtc agttttagct tatcccctgg caaaatcgtt ggattagtag gtcctaatgg
     7321 cgctggaaaa acaacgatca tgaaagctat tttaggactg atccattact cagatggaac
     7381 aatctgtatt ggtgaaaatg agatttctcc ctctagtcat aaagggttgg aacaagtagg
     7441 agcattgatc gaatacccgg gtatctatcc attcttaaca ggctatgatc atctgaagtt
     7501 attctctgaa accaacgatg tatctgctat cgacactatc gtgaatcagc tcaagatgga
     7561 aaagtacatt cacaaaaaag cgaaatccta ctcgttggga atgaaacaaa aattgggaat
     7621 tgctcttgcc ttactgaacc atccgtctat cgttatttta gatgagccga tgaacggttt
     7681 ggatccacaa gcaacaagag atgtgcgaaa aatcattacc gacttggcta ctcagggcac
     7741 ctctttcttg atctccagtc acttactcag cgagcttgaa aaaatggtcg atgagctgat
     7801 cctgatcaat caaggaaaga tcatcaaaca atgtacaatg gctgaattga accaaacagc
     7861 gcaagatttc atcgttatct ctacaacaaa tgatctagct gctcgaacga tcttgacaga
     7921 agctggatat actttggaag atcctgataa aatcaagctt ttaaaagaaa acgaagaatt
     7981 attaggaacc gtgatccagc tattgtctgc acaaaatatc catgtgacag acgtccagca
     8041 tctgacgaat gatttggaat cttctctatt ggaaattctg gattcagtaa agggggaaga
     8101 agaaaaatga cattgcttgt aaaacaagaa ttatttaaat tgatcaagaa aaagtcaact
     8161 gctgttttat ctgttctatt agttgttttg ctcataggaa cagcacttct agccaaaaaa
     8221 tacacgacga tcattgatcc agttgaaatg actgctcagc tttttagtgc cacatcttgg
     8281 attgtcttta tcatgattgc agctgcaagc acgatcattt cgatggaagc acaatatggt
     8341 acattgaaaa atctccttta tcgaaagtat tctcgaggag aaatattagt aagcaaatgg
     8401 atcacattag ttatttattc tgtttattta taccttttag ctattattgt cactgtgttg
     8461 atgaaactga ttcttttccc ttcgatttcc ttcacggaga aggtttctac tggtcaaaca
     8521 ctgatccaaa gcttgttcac ttatactttg ggtagttata tcggtttatg gctgatttta
     8581 agtttagtgt tgatgattgc ttgctttatc aatagttccg gcgcatccat ctcagcagga
     8641 atcgtctttt attttgcttc gtcaatcata tctggtatcc ttattgcact catccaaaaa
     8701 tgggagtgga tcaaatggaa tccgatcagt atgttgaatc tgcaaaacca aattggaaac
     8761 gaagagatca tgaagcaatt gactcatctt tctactaatc aaatgctatt cggtaattta
     8821 gcttacatcg ttttgttctt agcattagga tatctcgtat ttaagcgaaa aaatgtatga
     8881 tgactcatca aaaaagaggc tgtgaaagag acgttcagcc ttattgccga ttggctgtct
     8941 cttaaacacc gtttattctg aaaaaggagc tgtgacaaca tttgtgtcac agctcctttc
     9001 ctagtatgtt tttgaataaa cgacaggctc acaacctctc tttatacttc ttttatactt
     9061 ctatacgtga agcatcccag tggcaaataa aaccattgca atcactccga ccatcgtcac
     9121 acctataagt aaaatcttat ctaagtggat atgttgtaca ggctcgtttt gctccttacg
     9181 tgctttgagg taaaaataaa tgcctggcaa gaaaagaaca agaacaagca ttacttcatt
     9241 aaaggctacg actagcatag cccatacttg aaaggcactt gctaaaagcc ctactaaaaa
     9301 ttggacccat tctttccgct gataagaaag tttcatttgg tacaatccta agaaaagcca
     9361 cgtgaagaaa atagctgctg taccaagtgt gtaagcaaag ttataagcac tgtcagtgaa
     9421 taataatgaa agtaaaaaga cattcgtaca taacgtcgtc aatacgatag cataagttgg
     9481 tgccccattt ttgttgagtt ttccccatgc tttaggcaaa agtccgtctt cagccatgtt
     9541 tcccattgtt tcaatcggta agatcgtcca tgagagccaa acaccaacta aagaaatgat
     9601 caaaccgccg ttgatcacga ctgctcccca tttaccaacc atcatttcaa acacatagcc
     9661 catagcaggc tgcgccttga tcgtttgcag ctgattcatc gtcattgtcc catatggaag
     9721 catggaaacc aagacgtaaa taataatcaa gccgaatatc cctagaatcg ttgctttccc
     9781 aacatctgat tgtttttttg ctcgtgaacc tacgacagag gctccttcaa taccaacaaa
     9841 tacccaaagc atcaccatga tgcaactcaa tacttgactg gaaaacggga tcggctgtcc
     9901 attcgcattc aatataatgt cgctagaaaa gttatcaatg aattgttgga tcgaaaacgt
     9961 gctgatagct actacaataa ataaaaataa tggcactaat ttacagaatg tgacgatagc
    10021 attgacgaaa ctagcatttt cgactccccg attcactagc catgcatatc cccataaaaa
    10081 gactgtactc atcacgatcg atgccagatt ttgcccacct tcaaatactg ggaagaaata
    10141 tcctaatgcg ctcatcaaca atgttgcaaa agctacgttg cctaaccagc atgtgagcca
    10201 gtaaccccaa ccgctgataa aaccagcgaa acggccaaaa ccttcttctg cgtaactaaa
    10261 gatcccgcct tttaaatctg gacgtttttt attgatatta ttgatcgaca aggagagcat
    10321 caacattgct gttcctacga gtacccaact gaaaatagct gggccgccag ccgatccgga
    10381 gatgtccgtc ataataccaa atacgccacc tccaatcgct gaaccaatta ctaaggcagc
    10441 aagtggaatt aaaccaattc cttttttctg ttgctctgta tccatgtaag catcctccaa
    10501 aataaaaccg cttttatcaa aaagtataac aaaccttttt tatttttact taattaataa
    10561 aaactttaat agaaatataa ttctaccggc ttttttctca ttatacaagc aaagcgccta
    10621 gtccctttcc aaattacacc accaaaaaac ttaaaaaaga tgctatacta aaaggaaaga
    10681 attggaggat gatccatgaa cattttatat atatcgattt caggaaatac gcgtgccttt
    10741 gccaaacatc tagcagaata tgctgaaaaa atgcatgcag aagatcctgt caatcctgaa
    10801 gttactttaa aagaaatcca tgaaaatagt gattttacga aagaaacaga accatttttt
    10861 actttcgttc ctacttattt agacggcgga aatggtttag ataacggtga tacagaaatc
    10921 ttgaccgaaa cgatgcgtga atatctggaa catgaagaca atcataaact ttgtcttggt
    10981 gtagtcggta gcggaaataa aaacttcaat aatcagtatt gtctaacagc caaacaatat
    11041 gcacaaacat ttggctttcc tttcttggca gattatgaat tacggggaac accatctgat
    11101 gtgacacgaa tttatcagat tttagcagaa aacaataaat aataaaaaag aagaagctga
    11161 aaaatagatt tcagtttctt ctttcgtttc tattgtttct atcatattaa gctttgacat
    11221 ccatcacagg tgcttttgct tttgctttac ctgttttttc caagacaaag ttttttacac
    11281 gatccatatt ggttaccaag acgatcatgg atgtttcttt gcctgctgct ttgatcgctt
    11341 ctaagtcagc ttctgctaca agcgtatcag gtgtcacttg ctgcccttct gttactttca
    11401 catcaaatgg cgtaccgcct aagtcaactg tgttgattcc catatgaagc aagatttcta
    11461 aaccatttgg cgttgtgatc ccaatagcgt gtttcgttgg gaagacagag ctgactaccc
    11521 cagtaactgg agaatagata tgtccgtttt ctggttctac aaagtagcct tcacccatca
    11581 tcttttgtgc aaaaactgga tcacttgctt tatctaaaga aacaactgtt ccgtcagcaa
    11641 ctgatgagag gatagtcaca ctttcagctg aagtttgagg tactactttt tcaggcactt
    11701 catttactgt ggctgtttca gtcgctaatt cttctttttc taaacggtct ttaggaatac
    11761 cgaagaagaa tgtagcaacg aagccaccag cataagctgc caataatcca aggatgtagc
    11821 ctaaccattt accgtcagag atcaatggga tcaaagcggc tcctgaaggt ccaatagcga
    11881 tagccccgac atttccgatc attccgatca ctgccccgcc gatacctcca ccgatacaag
    11941 cagtaataaa tgggcgtcct agaggtaatg ttactccgta aatcaatggt tcgccgattc
    12001 ctaggatccc gactggtaaa gctcctttga tcatttctgt taattcttta tcttttttgc
    12061 agcgaatcca taatgccaat gctgcaccca cttgtcctgc accagccatc gcaagaattg
    12121 gaagcaatag cgtacgacca gtttcatcaa tcatttgcac atggattgga gtcaaaattt
    12181 gatgcagtcc gaacataacc atcggcaaga ataatgtgcc tagaacgaag ccggcaaatg
    12241 ctccaccaac gccaagtacc cagttgatcc caccgaccat gccatcagaa atgaaacctg
    12301 ctaaaggcat gatgaagaaa atttcaatca gaccgatggc aatcaatgaa agagttggtg
    12361 taacgatgat atctaccgca tcaggtacta ctttatgcag ttttttctca acgattgaca
    12421 atagccaaac agcgaagatg acacctagga tcccaccttg tccagctgca agagcttcac
    12481 cagtaaataa gtttttcagt ggtgcttccg gattcatccc tgtcagcatc acaacggccc
    12541 cgataactcc accaagagtt ggtgttgcac caaaaacttg tgcagcattg atacctgtat
    12601 agataactag gtagctaaac atcccgtttt tcaagatgtt catcacatcg atatattgtt
    12661 gccatgttgc tgcatcaagt gttccggctg tgactaagtt tgctaaaact gcggcaatcc
    12721 ctgccacgat cccagtaccg acaaatgcag gaatcattgg cacaaagata ttagaaatgt
    12781 cttttaatac cgatttgatt ttagatggtt tttgtttcga tttttgtgcc gctttcattt
    12841 cttgtgcccg ttcgtttaca cggtcttttc cagatgctga tgaatttgct gtagctgtac
    12901 ttacagaaga aagtttttct cctaatttca cgcctgccaa atcaaccatt tgctgtgcta
    12961 ctttgttcac tttcccaggt ccgatgatga cttgaagctg ttcatcttct actacaccaa
    13021 gcactcctgg aatcgctttt aattcagaga catttacaag atcatcattg atgatcttca
    13081 tacgcacacg agtcatgcag tggacaatgc tttctacatt gcccatgccg cctgcccctt
    13141 tataaatttg ttttgccagt tcttccaaag tcagttcgtt ttttgccatg gtcttttccc
    13201 cctcataagg tcccttttac aaatccgttt gcttcagcta attttgcttg agcttcctct
    13261 ttatcactat ttgtcaaaat catgacgata gccagcttaa cattttgatc tgcttcttca
    13321 aagtactttt cagctgtttc gtaatcagct tctgtcgctt gcatgatgat tcgttttgag
    13381 cgttcgatta gtttttcatt tgttggtttg acatcgacca tcaagttatt gaatacttta
    13441 cctataccaa tcatactgat agtagaaatc atattcaaga taagtttttg tgctgttcct
    13501 gacttcaatc gagtagagcc tgtcaaaaat tctggacctg catcgacttc gattgggaaa
    13561 tccgcgtgtt tactgatttc ggcttgttta ttgcaagaaa tcgttcctgt gacagcaccg
    13621 atcgattttg cgtaatctaa tccaccgatc acatatggtg tacgaccgct agctgcgata
    13681 ccaataacta tatcattttt tgtcaaattc agcttgatta gatcttcttg ccctagctca
    13741 taagaatctt cggccccttc gacagctaca gtcattgctt cttctccacc agcaattaga
    13801 cctatgacca tttccggttc tacaccgaat gtcggtacgc attcagcagc atctaacaca
    13861 cctagtcttc cacttgttcc ggctcccata taaatcagac gtccaccttt tttaaaggac
    13921 tcaatcgtgt tagcaatcac tggttcgata cttgtcagtt ctttttcaac cgcagcggcc
    13981 actttctgat cttctttgtt cattagttga acggcttgag aaatactcat ctcatctaat
    14041 ccaaaagttt cttggtttct gcgttccgtt gttaggttct ctaaattgat tttgctcatt
    14101 tttatcttcc ttcttttctt ataaattgat agttcatacc agctttgatt tggttgatca
    14161 atggtagctc ttctttgata actttagcta ctacattcac tttttcatcc gctggcaaat
    14221 catatttggt taattggatc tcacccatat agcgcaaata cttttcgtta tctaaagtaa
    14281 tagacccttt catacgcgta gctgtatttc ttgctgggat aggcggaatc tctcgaaaac
    14341 gtgcatctac gcttcgtatg acatctcttg catcgtcttg ccgattcgta tgcttcccta
    14401 atatatattc gtaaaattct tcatctacag gttccgtatg gagcaagact gtctgttctt
    14461 tttggaaaga agcaaattgc tcctgaacgt tttctgacag acctgcatct ccgatgtaaa
    14521 caatatccgt gttacttgct aatagatcta gagcgcctgc aagaggatgg atccctcgat
    14581 gttcttccaa agttggcaat ccttgatata gtgggcctct caactctgta tctcctggta
    14641 caaaaccttg gacaaggaga ccttgaattt tgagccattg attttttttc tgataccatt
    14701 ctttgtccag ccctgtttcg ggacgtggat aataattatg ccaagcttca atctgtgaga
    14761 aatcagcttc tgcttctttc aattcatcga tatctttagg cgtgatcgtg ctagcattca
    14821 aactgatttt caattgatgt gaccagtcgg caatctgctg attggaaata tgataatcca
    14881 ttcttaaacc tgttacacca attgctttca aaggcgttag atcttctaat gaaaaacccg
    14941 ctcgttccaa tgcctctcct gaaatatcga ccatcaattc tagtttattc tttttcgctt
    15001 cgcttcctag ttcgatcaat cgcttttgat atgccgaaac atcatcttct ggtatatgca
    15061 tggaagtgaa aataccgaca aagccattgg atgccatttg gcggatatac tgtttcttct
    15121 cttctgacaa agaatcgttc ataaatattg aaaagccaaa catattatcc ctctttttct
    15181 gtatccgtct tcatttctat gact
//
LOCUS       DAFTHM010000061        15102 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFTHM010000061 DAFTHM010000000
VERSION     DAFTHM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15102
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.061"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(110..565)
                     /locus_tag="L7C88_001856"
     CDS             complement(110..565)
                     /locus_tag="L7C88_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558671.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(719..1927)
                     /locus_tag="L7C88_001857"
     CDS             complement(719..1927)
                     /locus_tag="L7C88_001857"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBP9558672.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2039..2371)
                     /locus_tag="L7C88_001858"
     CDS             complement(2039..2371)
                     /locus_tag="L7C88_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBP9558673.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2519..3394
                     /locus_tag="L7C88_001859"
     CDS             2519..3394
                     /locus_tag="L7C88_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBP9558674.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3476..4057)
                     /locus_tag="L7C88_001860"
     CDS             complement(3476..4057)
                     /locus_tag="L7C88_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBP9558675.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4063..5322)
                     /locus_tag="L7C88_001861"
     CDS             complement(4063..5322)
                     /locus_tag="L7C88_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBP9558676.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5324..6370)
                     /locus_tag="L7C88_001862"
     CDS             complement(5324..6370)
                     /locus_tag="L7C88_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558677.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(6605..6880)
                     /locus_tag="L7C88_001863"
     CDS             complement(6605..6880)
                     /locus_tag="L7C88_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBP9558678.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(7123..8433)
                     /gene="der"
                     /locus_tag="L7C88_001864"
     CDS             complement(7123..8433)
                     /gene="der"
                     /locus_tag="L7C88_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBP9558679.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(8615..9844)
                     /gene="rpsA"
                     /locus_tag="L7C88_001865"
     CDS             complement(8615..9844)
                     /gene="rpsA"
                     /locus_tag="L7C88_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBP9558680.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(9979..10659)
                     /locus_tag="L7C88_001866"
     CDS             complement(9979..10659)
                     /locus_tag="L7C88_001866"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBP9558681.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(10708..11343)
                     /locus_tag="L7C88_001867"
     CDS             complement(10708..11343)
                     /locus_tag="L7C88_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBP9558682.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(11409..12812)
                     /locus_tag="L7C88_001868"
     CDS             complement(11409..12812)
                     /locus_tag="L7C88_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBP9558683.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(12799..13830)
                     /locus_tag="L7C88_001869"
     CDS             complement(12799..13830)
                     /locus_tag="L7C88_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558684.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            13861..14082
                     /locus_tag="L7C88_001870"
     CDS             13861..14082
                     /locus_tag="L7C88_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBP9558685.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(14247..14984)
                     /locus_tag="L7C88_001871"
     CDS             complement(14247..14984)
                     /locus_tag="L7C88_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBP9558686.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
BASE COUNT         4201 a         3197 c         2566 g         5138 t
ORIGIN      
        1 aaaatcttgt cacagtccct tattctgaat aaacggtgtg gaagagacag cctatcagta
       61 gtaataagac acatctcttt cacagcctca tttttgcgta aaaatcgatt tattcgaaaa
      121 attccccgta tacatcttct acacgttgat ctggattgat cacgatatac aagttacctg
      181 ttttttcgct gatttttgtt gattgatatt gattgtctaa tccttctgtt cctttatcta
      241 gatatgggaa gtacacaaga tcaggtgtgc catttcggta aaggatttcc attcgctcga
      301 tatcttcgta tttcaatgcg cgattaaaca tgcccatttc cagtccgcct aggttgatat
      361 catgtgtcgc aactgcgtcc ccttcatgga agatttcgat tttaaatcca gcacacggat
      421 ggatttcaac aaattcactg ccattgattc gtccaaaact tgttgtgatt tgtttgatcc
      481 aaagatcgcc gatatgacgg cggttgatcg tccaggtttc tccatttcta aaataaaatt
      541 ttagcgctgt catttcttta ctcattaaaa agactccttt atgatgtaat ttattcttgt
      601 actacctcag tttagcacaa atttatgtaa gtggtcacat cttatgtttt ttcttctaat
      661 gacgtatctg cccactttaa gtagccaaca aagctgagca gatacagtct agtgtttttt
      721 aaatcaattt ttctttcgat aaaaaatcca aaacctgttt tttatcattt tttattcttt
      781 gttctacgac ggctttttca gctaattgca aagcttcact aacccactta ccaggttttt
      841 ttccagtttc ttctagcaag attttaccat ctactgctaa ttcgcttaat gacttgatag
      901 gtaaacgatc ataggattct cctacggcat ccatctgagg tgtttcgtca aaatagatca
      961 tcaattcttc tacttgcagt gcatgttttt tgcctaagaa gtacaattcg aatggttcca
     1021 aagctccagt ttctcgttgt cgtagtcctt ggacaagtgc ttgaacgtct ttaatcattt
     1081 ggttagaaca cttccacgat ttcaaaaagg aacgaatctc attttctttt agatccagtt
     1141 ggctgatcaa taatgcccat gcttggctct cttctttcaa tgggacggat ggtaattcag
     1201 caaaacgtaa aagtgcttcg ccttcttctt tcaaaccggg acagcaaatg tagcactctg
     1261 tttcaataaa tgcatggatt cccgcggccc gttcatttcc caagagcatc ttgatgaatt
     1321 ccacatttat acgttctaca gatattttac ctaatagctc gtggttttct ttgatggcgt
     1381 agaaggtttc ttcctctaat ttgaacccta gttgactgac aaaacgcaac ccgcgcatca
     1441 ttcgtaaggc atcttcatgg aaccgctcat gaggattgcc tacagctcgc aagatctgtt
     1501 cttctagatc ttgcagacca tcgaacaaat cgatgatttc tccatcttct ttcaaagcaa
     1561 acgcattgat cgtaaaatct cttcttttca aatcttctgc caacgaacga acgaattcga
     1621 catgatctgg tctacggtag tcctgataag ttgattccgt ccgaaatgtg gtgatctcat
     1681 attgttcatc attttctaat accaacacag ttccatgttc gatcccaata tctatcgttt
     1741 ttggaaaaag ctgtttgatt tcttctggaa atgcgcttgt tgcgatatcc acatcatgga
     1801 ttggctggtt cagcaagata tcacgaacac ttccacctac aaaataagct tcatatcctg
     1861 cattctctaa ttttttcaga actggaattg ccttttggta ttccagaggt aattgtttta
     1921 atttcatttt tccaaccttt cctgcgtgtt tcttgtcctg agataaagac tcagttgcat
     1981 ggtgactgtt tgacaagtcc gtttcagagt cttcaaggcc aggaccactt catcttgttt
     2041 actcgtcctt acgctcaaag cgattatggt ctctttgatt gaatttttcc atgttttttt
     2101 caaaaacttc agttaagtcg atattcaatg aattagccat gatcatcgta acgaataaaa
     2161 catcaccaag ttcttctgct accgagttaa ctggttcaga agcctttttg cttttttctc
     2221 cataagtgtg gttgacttct cttgccaatt cacctacttc ttcagttaat cgagccatct
     2281 gagctaatgg agagaaatac cccaccttga attgctggat atattcatcc acttcctgct
     2341 gcatactgta taaagaacgc tttttatcca tctttttccc tccaaaacta tcttaccaaa
     2401 actttaacgc aaatcctaga taagagcaat tgagaaaatc gaatttccat gctacattta
     2461 ggaaggaatt tctaaatgga aattctgtga aaatacataa ttgaaagctg gaattcatat
     2521 ggtcaaacga aaaacagtaa aagaagttct ttttatcatt ataggaacaa gtatttatgc
     2581 atttggtctt gtttacttga acatcgctaa tcatttagca gaagggggag tctcagggat
     2641 caccttgatc ttaagagctt tatttggtat tgatccagct tatacgactt tattaatcaa
     2701 catcccattg attttactag gaggaaagat cctcggtaaa cgttccttgg cctatactgt
     2761 tctaggtaca ctttctttgt cattcttttt atggatctgg caaagggttc cactagaaat
     2821 caatttacag catgatctac tgatcgtttc tctacttgcg ggtttagttg caggtgtagg
     2881 aagcgggatc gtctaccgca tgggtggaac aacaggcggc agtgatatta tcgctcggat
     2941 tttagaacaa aattacggca tcactatggg gcgttcccta ttggcatttg atatcatcgt
     3001 cttacttgct tcattaacct atatcgactt gaaacgtatg atgtatacgt tgattgtttc
     3061 gtatgttttc agtcgtgtga ttgattcgat cttagatggc ggatattctg caaaaggtct
     3121 acttgtcgtc tccaacaaaa gcgaagagat tgcaccacta ctgatgaccg gtctgcaaag
     3181 aggtgtgact ttcctttctg gagaaggcgc attctctggt aattcaaaaa aaatcatcta
     3241 tatggtcgtt agctctagtg aattaactga agctaagagg atcgtccacg agattgacga
     3301 aaaagctttc ctttcaatca tcaatgtgca tgaagtggaa gggcaaggct ttacttattt
     3361 gaagccacag acaagattac tgaaaaaact ataagaaaaa agacaaagat aggctatgag
     3421 gaaagattcc acatccagct gacctttgtc ttttttagta ctatactatt tttaactaat
     3481 tgttatgttc acttacccgg ttacttttct tttgtgtctg caaaaggatc tttcggttaa
     3541 cttcatcaga taatttcaaa aaagcatccc tatctccatc ttctagtgct tgatcgattt
     3601 gagcataaag catttttagt tttgcctctt cttctttttc ttgaaaatat cgttcaatta
     3661 attcagtatc ttcttcactg actgaagaat cccaagaaga aaatggattg tcttctaaga
     3721 tagatagata ttctcttgtc tgccaagcat tttcgaatat acattccaca tataaaggct
     3781 ttttccaatt caaacggatt tcatgaaaaa tctggtctgt gtccgtaaat tcttttccct
     3841 gcaaaaacaa tttcatgggt tccccttcaa cagatagatc actgatctgc agtcctcgat
     3901 ccgcaaaatt cgccccttca acaaagtgga cattgcttaa aatcgcttca tgattggcaa
     3961 gataattcaa gatccaaaaa acttctcttc ggctaaaaga tacatgattg accatccacg
     4021 ttaaaaaatt cttcttttcc cgtacatcaa ttagcatttt tctcacctct ctgttaggtc
     4081 atctaataat gacagtgcct ccatatctcc tggttcaagt gttaaataat aagtcaataa
     4141 ttcttgcgct cttttcagct gcccttcttc tcttaagaaa aaggcatact ctttcaagaa
     4201 atctggttca tgtgatagtt catgataagc ctgttcatag tgtacagctg caacggtaaa
     4261 gtcttctaat tcattataag catgggctag gttccattct gcataaggat tagcagtttc
     4321 ttccatctga ttgatcactt gtatcacatc ttcatatctt tcatcatcca agtaaagatt
     4381 acttaaagta agtaatgttt catcttgttt gtctcctact tctaaagctt tcagtaaaag
     4441 ttcttctgct cgctgtctat catgcagacg gaaagcattt tccgaggcca ggtgataaag
     4501 ttcgacttgg taaggatttt ctttgattcc ttcttctaac actgtttgtg cttcttcaat
     4561 catttcttct tcttgaagag cttgtcctag atatagatat aacgattgat aatgcggatt
     4621 aacttctcga agttcttcca gatagttgat tgcctgctga ttttctttca attgaagatt
     4681 cgtaaaagct agctggaaca gtcgatcatc tgtcctttct tctttcagtg cttcttctaa
     4741 aggtacgata gctgcttcga attctccttg catacttaag gattgtccta aacgttcctg
     4801 catcgagatt cctgaaattt catttatccc gcttgccaac aatgtttcat aaaccactgc
     4861 tgcctctttg aaacgatcaa ctgaaaaata caattcagct agcgcaaact ggatcaatgg
     4921 ttcatcagga agcaacccag ctgcttcttt caattttgct tcactcactt cagggattcc
     4981 gataacttgg tacaaatcag ctatcgccaa taagctttgc ggatagtaat cactttgctt
     5041 atccactttt tccaggtatt caaaagctaa gtcgatctca ttatcttcga ttgcaatttc
     5101 tgctaacggg atgttcagtc cgtcattttc tgggtattgg ttgatcagtt gttcaaaaat
     5161 ctgttttgct tcgatcaaaa agccaatagc cagcaattct tcgcctagtt cagctaatat
     5221 atctgctggg tcttctttta atgctttttc taaaaagatt tgtgcttgtg acaagtcttc
     5281 atctgataaa gcttgcaaca ttttttcgct atttgtattc atttcaattc cctcttatct
     5341 cactgacgat ttgttgaaat accgtcattg ttctcaataa ttctttttcg tttggatgtt
     5401 ggtatccgtc tattatacct attttttcta aaacaagtat ttttttgctt ttttctgcca
     5461 aaaaaagaac tttttccaaa tactccatct ttgaaatctg ttccagccag tggattggat
     5521 agccaagcaa gtccagccac acaaaaaagt tttttagttg gaaatcaaaa ggatatgctt
     5581 ggagattcca cacgaaatga aacatcattc ctaaaaattt tttcatacta gcagaaagta
     5641 gatggccatt ttcggtcaga taaaaagctt gttcaaacag tttaccataa tttgacaggt
     5701 tttctgcctc taattgataa aaatagatca tttcttcgat catcccggca aacggccgag
     5761 tcgttaattg ctttttattt ggatagtttt tatacagatt ttgcaaaaaa cgatgatcac
     5821 aaatcattcc gcaacagata aaagtcaaaa agtcaatctg ctttccgtcc acctgccgct
     5881 cgctgattgt ttgatcataa acgatgcgtt ctggcagatt gatggtttgc agcactacac
     5941 gatttggtag ctgcaaaatc gtccgctgcg gtgttaatgc tcggcttaga gaacggatcg
     6001 atacagggat catccatagt gatgaatcaa gggttgtatg tttttgaaaa aaacctgcca
     6061 gatccatgat cccttcattt ccaaatccga tgataaacat ggattgattt tcgggatagc
     6121 gtttgacgaa atcaagcagg ttctttaatt ctgttaaatg attgcattga gtgttggcac
     6181 aaatatacca gtcattgttt gcttgatttg caaataacgg gttgatctta tctgcaaaca
     6241 aatcataata gcgctgattc gttaaaaata agattggctg atcaatggaa agttctctta
     6301 gctgactgac tagcgtttct ccgtaaaaca ctttcgtcaa cgcatcttct acttgataat
     6361 caagttccat acgcatccct cctcttctta tttttatttt accattagta agcaaattct
     6421 agaaaagata agagcaaagc tcacctcata acttggaaat aaataaaaat taaataaaat
     6481 acatgtgttt tctatgtatg acatacggat tcggaatctc tgtctcttat ttattccttt
     6541 tctgctagga aataaaaaga aaagcacttg tagccctaga gccacaagcg ctttttcaac
     6601 tgtcttattt aacagcgtct tttaatgctt tacctggttt gaatgcaggt actttgctag
     6661 ctggaatttc gatttcttca ccagtttgtg ggttacgacc tttgcgagct gcgcgttcgc
     6721 gaacttcaaa gttaccaaaa ccgattaatt gaactttttc gccgttagct aaagcatctt
     6781 gaatagttga aaatacagca tctactgctg cagttgcatc ttttttagtt aaatcagtag
     6841 ctgaagcaac tttttcgatt aattctgctt tgtttgccat ggatagattc acctcctcca
     6901 caagagatat gatagaaata tcatttagtt aaaactttct gagtggtcca gaagtttaaa
     6961 aagaaatatt gattaacttc aatattctgt tatcacgata tcatatgaac cgcttaatag
     7021 caaggttttt accaattttc acatgctttt tttagtcata gaaacgtaac aaacgaaact
     7081 gtctttttct tttgaaaaaa aaacgtcgat atggtaaaat gcctattttc tcctacgagg
     7141 gataattcgg atggacgtcc cttcaaaagt aaatgctttt ctgatttgat tttctaagaa
     7201 acgttcataa gaaaaatgca tcaattcctc ttcattgaca aaaacgacaa atgtaggtgg
     7261 tttgacagcg acttgtgtag cataaaaaat cttcaggcgt tttcctttat ctgttggtgt
     7321 tggattgatt gctacagcat ccataatgat atcattcaac acagccgaag agatacgaag
     7381 attctggttc atacttactt gttcgatcat ttcaggcaga cgttccaacc gttgtttagt
     7441 cactgcagaa acaaaaacga ttggagcgta atcaagatac cggaattcat cacgaatctc
     7501 ttgttcgaaa tcacgcattg tattggtttc tttctttaca agatcccatt tattcacgac
     7561 gataataatt ccacgaccag cttcatgggc gtaacccgct actcgcttgt cttgttcccg
     7621 aatcccttct tcagcattca gtaccatcaa aacgatatca gaacggtcaa tggcacgcat
     7681 tgcacgcatc acgctgtatt tttcagtatt ttcgtatact tttccgcgtt tacgcatacc
     7741 agctgtatct atcattaaga atttctgacc actttcagaa acgaagtggg tgtcgattgc
     7801 gtctcgggtc gttccttcaa tatccgaaac aattacacgt tcttctccta aaatcgcatt
     7861 gatcaaagag gatttaccaa catttgggcg accaatcaaa ctaaacttaa tcgtgtcgtc
     7921 gtcctcttct tcagtctctt cagagaaata cttcactgct tcatctaaaa tatcaccaat
     7981 ccctagtcca tggcttcctg aaacaggata aggatcgcct agccctaagg aataaaattc
     8041 atagatatcg tttctcattt ctggattatc tactttattg actgctaaaa tcactggttt
     8101 attacttctg tataaaattt tcgcaaccat ctcatctgcg tctgtcacgc cttcgcgtcc
     8161 gctgactaca caaatgatta catctgcttc ttcaatcgcg atttctgctt gatgcttgat
     8221 ctgatccata aaaggttcat cgccaagatc aattccgcct gtgtcgatca cgctgaattc
     8281 tcgacctaac cattcacctt ttgcataaat acgatcacga gttactccag gagtatcttc
     8341 gacaatcgag atacgctcac cagcgatgcg gttaaaaatc gtagacttac cgacgttcgg
     8401 gcggccaacg attgcaattg ttggatttgc catattattt cctcctcaca agtttccaat
     8461 ctcacttagt ttaacgaatg cattgccaac tttcaagcat agattgtcaa ttaaacgaag
     8521 tatttttatt ccttattgaa atactaatcg cttttcaaaa gaaaaactga gacaaaagca
     8581 gctgctttca tctcagtcac agatacaaaa tcaattattt ttcagaatca tcggttgctt
     8641 tttcttctac ttcttctttc aacgcatcac ctaaaatgtc tcccatagta aatccagtat
     8701 tttcttctgg taattcataa gactcaacat tttttggttc ttcttctgaa gctggttttt
     8761 cttctaaagc tttgatactc aatgcaatac gatgttcttc tggatggatc tctaatactt
     8821 tcactttcac ttcgtcacct tcatgaagca cttcatgtgg tgtcgcaata tgtttatgtg
     8881 aaatttgaga gatatggact agcccttcta ctccagggaa cacttcaaca aaggcaccga
     8941 agcttgtcaa acgtttaact gttccgtcta atactgtgcc aactggagct tttgtatcga
     9001 tttctgacca aggtccaggc tgtgtgtctt tgattgacaa ggaaacacgt tcttgttcag
     9061 gattgataga caacactttg acatttacat catcattgac agccaataca tcacttggtt
     9121 ttgctacatg actatgtgaa atctctgaga catggactag accgtcaatt ccgcctaggt
     9181 cgacaaatgc gccaaaatca gtaagacgtg caacacgtcc actgagaaca tctccctcat
     9241 ggatagttga aagaatttct tttttctttt cttctctttc gttttccact accgctttat
     9301 gcgataagat caaacgattt tctgatggtt cgatttcgat gattttaaag ctcaatgttt
     9361 tgcctttata gtctgaaaag tctgcaacaa aatgatcttc caccattgat gcagggacaa
     9421 aaccacgtac accgacgtca acgactaaac cgcctttgac aacatttgta acaggtgctt
     9481 cgatgacctt gccctcttgg aaatctcttt cgatatcttc ccaaactttt ttagcatcta
     9541 aacggcgttt tgaaagtagg tagctgccgt tttctttatc tttgccgatc gtactgataa
     9601 cgactaaatc taatacatca ccgactttta ctacttcgct gatatcttct accggcaaag
     9661 ttgataattc ttttgccgga acgactcctt caactccagc cccttcgatt ccgacaatca
     9721 cttgtttgtc ttcaatgact aaaacttcgc ccttaacaac atcgccaact tttacttctt
     9781 gtacgctttt cattgcgtct tccattgact ggttgttctc ttgattttga tcaaattctg
     9841 tcataacact tgtcctccta accaacattc tgccgtaagt acggtactgt ttttagttta
     9901 attgattatt caaaaaaaat aaagcgattt cgttcgtttt ccttgaaaaa acaattgttt
     9961 ttcatttttt ttcttaattt aaaaaagaag ataacctttt ttcaaaacaa cagcttttat
    10021 tgctgcaacg acttctggaa tcgatttgcc agtcgtatcg atacgaacag catcctctgc
    10081 ttgcttcagc ggagagacgt cccttgttga atcataatgg tctctttcct gtatctcttt
    10141 cgtcagtgtt tcaagatcag tcggaattcc tttttcttgg ttctctttga aacgtctttc
    10201 tgcacgctca cttacgcttg ctactaaaaa gattttcact tctgcattcg gtaatacagc
    10261 tgtcccgatg tctcttccgt ccatgacaac gccaccgcgt tcccctattt ttcgttggac
    10321 agcaactaat tcttctctga cttttccatg tgcagagact tcagaaacag cttttgtgac
    10381 atctggttga cggatttcta aagtcacatc ttttgatgct atgaatacat gctgtccatc
    10441 ttcttgttgc gaaaaagaga taggatactt tttgatcagc gaaactagcc cttcttcatc
    10501 tgaaaaagat acattgttcg taatagctaa ataagttact gcgcgataca tggcaccggt
    10561 atctgtataa atataattca attcttttgc taatatcttg gcaacggtac ttttcccaga
    10621 tgaagcaggc ccgtcgattg caatactgat ttgtgtcatg atataactcc tttttctcag
    10681 aaaaaaagcc gcaaagcgcg gctattatta tttaattctt aattcttgac cagggtaaag
    10741 cataaagttg tttggatcta agccattcaa ttcaaacaat tgatcagtgg tgatccctgc
    10801 acgctcagcc acttgttttg gaccttcgcc tgcttgaaca gtcgttgttg aaccggctgc
    10861 agctgatgaa gaaggtgttg tttctgctgc attgctgctt gaatcccctg cttgataagt
    10921 tgcctcactt gaggaagtcg gtgttgtctc tgctgcaata ctgctttctg acgttacacc
    10981 tgtatcttga gacacagtag attcttccgc gattgtacta gattctactg ttgaagtctc
    11041 agttgactcc tcttttgttg tacttgtaga actttctact actgatgtcg aagtttcaga
    11101 agaagttgct gctgttgcat tgttgcttga tccatttctg atccagaaat aagcacctgc
    11161 tggaatagcg atacataaga ccagtaaaat caaaaatagc gaaagaaata atgtatttcc
    11221 tttcttttgt tgtctctgag aacttcttga tgaaacttca tcatctgtat cgtagattgg
    11281 ttgttcccat ggttcttgtg tttcgttatt ttctgtagat tgatgtctat cttttctgct
    11341 cactgtttta cctcctaaac tctatcgtgt gtattatacc ataggaaaaa gtgtcttgtc
    11401 ctaaaaaatc aatgttccat gtttttttta aataaattta gtaaaatcgt ttcccaatga
    11461 agttgttcag tcttagaaaa aagcttcctc tttggcagaa gttctgcttt tgctccatca
    11521 atatcacaac aattctgcgg cttttcggag agtttttcgc caaaataagc taagatgaat
    11581 tttctgcggc agttttcttc attaatatag cgaagcatct gctgcaggcg gaattctttt
    11641 tctttttcct gacgtttgag ccgttccacc caattttctg gtttttcaga ctgctggatc
    11701 agctccatcc attttttttg cagctcatca aagggagctt gctttgtggc atattccaaa
    11761 taaagctcaa aactttgtcg ctgttctcta gaaagttgat taaagaaata atggatacgt
    11821 tcatccccac tttgataaaa aagaattgct gcactttctt cctgatctct gcctgctcga
    11881 ccgatttctt gtacatagtt ttctagactg tctggcaaat cataatggac cacataacgg
    11941 atatcagatt tatcgatccc cataccaaat gcattcgtag caatgagaaa ctgcagctga
    12001 ttttttacaa actgctgttg aagttgtctt ctttgagctg catcaagacc accgtgatag
    12061 tatccaactg taaaacgttc cctgaataaa tgatacaatc gttcgacttc tttttttgtt
    12121 gcacaataaa tgattgccgc tccttgtgct ctttccatga agtgttcaag ttcttgttct
    12181 ttttgctgcg ttttccgaac aaaaagcgag atattttgcc gattgactga ttgtctgatc
    12241 tcttttggtg gtcgatcaaa tagtacatga cgtatatctc ttgctactaa atctgttgct
    12301 gtcgccgtta gtgccagtgt gaccgggttt cctaaaagct ttcggatttt tcctaactgt
    12361 tgatattctg gacggaaatc aactccccat tgagacacgc aatgagcctc atctactaca
    12421 tataacgcaa tattttgttt tttcagatgc tctaaaagag aaggattagt caacatttcg
    12481 ggactcaaaa acaaaaattt atattgcgat agatgacgga ggacgtatct tctttcagat
    12541 tgcgaaagta aactattgaa agcagctact cgtttctccc ctcgtttttg taattgcgtc
    12601 acttgatctt ccattagaga aagcagcggt gacacgatga tgaccagacc ttccattaaa
    12661 taccccgtca attgatagca aaggcttttt cccgttcctg taggcaaaat agcgagagta
    12721 tcttctccat caagcaacgc ctgaataatt tcttcttggc cgggacgaaa tgaatcaaat
    12781 ccaaaatatt tttttaattc atttattaac attctgtatc gcttcctttc tcaatagata
    12841 gatttgatac aaacgaaatt ctccataatc taattgtcca tctacattcc attcgctaaa
    12901 gcgccactct cgcacggaat ccttatttgg ttccaaacgt tcgattgttt ctgcagagag
    12961 aatccactcg tatggaaaat catcaaaaaa caaggcccac tcaataagat gatctgttac
    13021 tgttcctctt tttaaatgac ggattgccat gatctggtca attgtctgac cattcataaa
    13081 catctgcttg gtgatcatca tgctttgatt gaaattttgc tgtaataatg aatcgatcaa
    13141 agcgtgccaa agcgaatctg gccgtttttc gatttgtgct aacaaaaggt ggatacatct
    13201 gctttgttgc agataaacct ctgactcatc attgtttttt gccagctgat aaggaagcag
    13261 ccctgttcgc tcatttccag ataattggtt agctaaaaaa tctgctgctt cttctggtat
    13321 ctccgaaaac agctgcacca aactctcata cgcagtatca atcaaaattt cacgtggcaa
    13381 ttggctttca ctaagccatt tttttagttg gaaagtataa aaaggacttg tctctgctgg
    13441 aagatagtct tgaatacccg ttgccagatt agaaattact tgaacagcaa atttaatgag
    13501 ccgccaacta gtttcccctg ttctgccata gcggtcaaaa cgcaaaccag tatgttctat
    13561 ttgatgttcg gacaacatat cagcccctgc aggcgttagc tttgcttcat tttcatttat
    13621 ttcgatccaa ccttgctgcg caattttttg caaaatttga taaaacttat cctgcttcaa
    13681 ttctggaaaa ctgttatgga taaacaaaag ttcgtgggta aatccataaa taagtactga
    13741 agtcgttcgt tttcccacaa ggagttggta aagagaacta atccgcagct tgtgtcctga
    13801 tgaaaatagc gataaaataa aaacaatcat attattctcc ttaagttagg atggttagaa
    13861 atgtcactac tatgtaaact tgtacctgaa cgctgtattg catgcggtct ttgtcaaatc
    13921 gaagcgccag atattttcga ttatgatgaa gaaggaatcg ttttatttgc ccaagaacca
    13981 gaggctcatc aacagttcgt gatgccggaa gaagaaacat atgtaaaaaa agcgtatcaa
    14041 aaatgtccag ttcgagcgat tttattagaa aataaaatat aaatataaac gaaactttaa
    14101 aaacgtacac taagttctct aaacttgaaa ataagccggg atctgtttct cttgttccgt
    14161 gaaatcccga cttattttga aagattcatt tgctatctat agttaattga ctagtttttt
    14221 cacggaccct ataggaccca tttatattat ttcaactttt tcagccagtt ttccaatgta
    14281 ttgacgatca cagtttgctg gtctgcgtta gaaatttctg cctctccatc tcctttttgc
    14341 tcaccatagc tgccaaaacc tccatgattt ccgccattga ttgatacata ctctgttctt
    14401 tccggtaaat actgcttagc ttcttgataa gcttcctgat tcaatacttt atcttttgtc
    14461 gccgtgatcg ataaaacagg aacagctgat tctgtcaatg ttcctttttt gtcgggataa
    14521 cttgccatga agaatacccc ttttaaatgt ttgtctgaat gattcttatt gacataacga
    14581 cttgccatta cgccacctaa tgaatggcca ccgatcacat aatcggaatt tggaaaatct
    14641 tctttgacct tatccgcttt gtttccgccc atcactgcta gatcaagtgg cattttgaca
    14701 atagcgactg aaaagccgtt ttttgctaaa tcttgcgccc aaatactata actttctggc
    14761 tctacgagag caccaggata aaaaataagt aatggagact ttccatgatt ctttttctct
    14821 ccttcaaaaa ataagtaatc ttctttgttt tttccttctt ttaccaacac ttgcgcttct
    14881 gacgatggtt cgtacgtatt ttgctgtata tagtaataac cggctccacc gagtaatcct
    14941 aaaatgatga ctaagccaat tagtattcgt ctaaatattt tcactttctc ccaccttttc
    15001 tatctgagtg accccttttt cttaatcaag tatgattata ccttaaaaaa ataagagaga
    15061 aatgcaaact ttccagcatc aaataaaaaa agacggaata tc
//
LOCUS       DAFTHM010000062        14925 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFTHM010000062 DAFTHM010000000
VERSION     DAFTHM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.062"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(406..1134)
                     /locus_tag="L7C88_001872"
     CDS             complement(406..1134)
                     /locus_tag="L7C88_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBP9558687.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1112..2686)
                     /locus_tag="L7C88_001873"
     CDS             complement(1112..2686)
                     /locus_tag="L7C88_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBP9558688.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2915..3853
                     /locus_tag="L7C88_001874"
     CDS             2915..3853
                     /locus_tag="L7C88_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9558689.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3865..4776
                     /locus_tag="L7C88_001875"
     CDS             3865..4776
                     /locus_tag="L7C88_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9558690.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4800..6272
                     /locus_tag="L7C88_001876"
     CDS             4800..6272
                     /locus_tag="L7C88_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBP9558691.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6323..6934
                     /locus_tag="L7C88_001877"
     CDS             6323..6934
                     /locus_tag="L7C88_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBP9558692.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6964..8877
                     /locus_tag="L7C88_001878"
     CDS             6964..8877
                     /locus_tag="L7C88_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HBP9558693.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            9005..11986
                     /locus_tag="L7C88_001879"
     CDS             9005..11986
                     /locus_tag="L7C88_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HBP9558694.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11983..13644
                     /locus_tag="L7C88_001880"
     CDS             11983..13644
                     /locus_tag="L7C88_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HBP9558695.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13684..14616
                     /locus_tag="L7C88_001881"
     CDS             13684..14616
                     /locus_tag="L7C88_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBP9558696.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4852 a         2357 c         2999 g         4717 t
ORIGIN      
        1 aaggtctgat ctttgaaaac taaaaaaata tgcggcgcac agaacgcgcc gcatatcgga
       61 ctaagtttta ttcaaatttg tcttcaccaa cacgatttga cgaagagcct atttaaataa
      121 ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa atagttcagc
      181 gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc tcagcggggg
      241 ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta aatattctaa
      301 tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact tttcaatggc
      361 tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata gaagcttttt
      421 acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa aatagctcac
      481 gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt ctttcagtag
      541 agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat aacctgtttc
      601 ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag ctacatcttt
      661 gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt gaattgactc
      721 attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca ttttttcttc
      781 ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac ttttaataga
      841 taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga caatactagt
      901 aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag aaattttccc
      961 catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt taaatgcttc
     1021 gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca aaagataatg
     1081 ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca acatgcatat
     1141 tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg ctttctataa
     1201 caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt gagatgccga
     1261 tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc agcttgtctt
     1321 ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt gtttcagttg
     1381 catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta atataatttt
     1441 caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga tcaatcagct
     1501 gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg tcgatattaa
     1561 ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga tacaacttgc
     1621 tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca gtcattcgaa
     1681 taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt gctgcatact
     1741 ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta gcattatcta
     1801 aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg ttttcgatat
     1861 tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt tcctgatact
     1921 gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga ataaacaaac
     1981 tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa taatttggat
     2041 tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt ttccatttag
     2101 aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa gaataattgt
     2161 aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga atcaatgtag
     2221 catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt ttttcgtttt
     2281 ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat atatttttaa
     2341 cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg gagcgatcct
     2401 ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca ttaaggtttt
     2461 cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata cgattatatg
     2521 tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt tctttttcaa
     2581 tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata aaaaaaatca
     2641 atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa agtcctcatt
     2701 ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg taaacgcttt
     2761 gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat tctattgtag
     2821 aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa ccaagtgggt
     2881 ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag ggttattagg
     2941 aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt tatggttatt
     3001 tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt tcagaatttc
     3061 atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg aaaatttcaa
     3121 atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg tttataacgt
     3181 tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc tgagccaaat
     3241 ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta attttttatc
     3301 atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag gattaattaa
     3361 tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac cgaagtactg
     3421 gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat ccatcattta
     3481 ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag ttgatggtgc
     3541 cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga ttattgtcat
     3601 tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt tttatcaatt
     3661 gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt atgtctaccg
     3721 tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat atcagtcatc
     3781 agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag atcctagttc
     3841 agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat gtacttttcg
     3901 ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag ctgtattttt
     3961 ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca actcaacggt
     4021 tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat acaagatggc
     4081 ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg aacgttgatt
     4141 actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt cccttaccgg
     4201 aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat ggttccttct
     4261 tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt gattctacct
     4321 cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa gtcgattcca
     4381 gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt ttttttccaa
     4441 atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc aagcttaggt
     4501 tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt gattccattg
     4561 caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa taatgacatt
     4621 acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac acgaatggca
     4681 atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca aaaatacttt
     4741 gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga tgttaaaaga
     4801 tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc cttggcctat
     4861 taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc acaaaagtta
     4921 cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca aaagtcaacg
     4981 aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg gacggggatt
     5041 atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt tgtttcgtca
     5101 atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc aacgatcatt
     5161 tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt gaaggtgggg
     5221 caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca acggaatatt
     5281 ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat gttgaaggtg
     5341 tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat acgaatatta
     5401 cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt atcggtggtg
     5461 gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat acttatgaga
     5521 ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa ggatatattt
     5581 tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa aactggtttt
     5641 taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa gctctagcgg
     5701 gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga tttgcaagag
     5761 tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg aaattgttga
     5821 attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt gaaggaaaac
     5881 actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat tattatcaag
     5941 gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt acagaagaaa
     6001 gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg tctcctattt
     6061 taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta caaaatatcg
     6121 tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa tatgtaccag
     6181 agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct gctcaagaac
     6241 aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa gaatagacta
     6301 agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat ttaattgggt
     6361 ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag gatttggaat
     6421 tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc gaaaaaaata
     6481 tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt ttgttagata
     6541 taatctatat tgctggtcag caactttgtt gttggccggc aatattacta cgatctggct
     6601 ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat cggtaattac
     6661 actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg ggttgtggat
     6721 gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc caacggtagt
     6781 catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc ctgtgatttt
     6841 tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg aaagagcgtt
     6901 agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg agtatttctt
     6961 tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca acttgagatt
     7021 ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac aaaggctaat
     7081 gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc ttattcacat
     7141 gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc tcaaggagga
     7201 gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt agatgcttct
     7261 cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt agcgttgatg
     7321 gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga ccttccatat
     7381 tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt tgaatttgct
     7441 tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt gacccaattt
     7501 ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact gatcggtgaa
     7561 gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat gtatcagaca
     7621 gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg atatttaagc
     7681 ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg tgtgttatca
     7741 attgttgata aatataagat gaaaccaatg atttggagtg atttcattta taagctatta
     7801 gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc attagcagct
     7861 aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga tgaagtttcc
     7921 tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca ttacgtttta
     7981 gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac agaagcaatt
     8041 gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat gttaactact
     8101 tggggagatg aagggcagga aacagagcat tggcattcct taattggggc attaaaatta
     8161 gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta cgatcgttta
     8221 ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga agtggatacc
     8281 attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg gcaagatccg
     8341 ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac tagaacaatt
     8401 ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg gaatccaaaa
     8461 caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat tttagcacaa
     8521 aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct tgcaggatta
     8581 atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt ggcatctatt
     8641 catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt agaacaacga
     8701 tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa tcatcttcag
     8761 gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca atatcaagtg
     8821 ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta caattaacga
     8881 aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt tcgttttcta
     8941 ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta ggaagtgaga
     9001 aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata cagaaccatt
     9061 acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt tagaaaggga
     9121 aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt atccttctgt
     9181 ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg atagaatttc
     9241 tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca atgtatctta
     9301 tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg tatatcggcg
     9361 tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag gagcagatag
     9421 taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga gtcatagtac
     9481 atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc aaattctagt
     9541 gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa tgagcggtct
     9601 atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt atcaactacg
     9661 gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc aacgatttac
     9721 tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg gacgtctcat
     9781 agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag attgcctttt
     9841 ttggacagca gaaacgccta aattatatac attactttta acatgtaatg gtgaatattt
     9901 taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat tgctgaacgg
     9961 aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag gcacgccagt
    10021 gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa atgtgaatac
    10081 tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg atgagattgg
    10141 tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc tatatgatac
    10201 tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga ttatggaccg
    10261 agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt ggtctatggg
    10321 gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac ggaaattgga
    10381 tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc aagtgaatga
    10441 ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg ttcatcgtca
    10501 ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc acgctatggg
    10561 caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg attcctttct
    10621 tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt tagaaacgcc
    10681 atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt tttgcgtaga
    10741 tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc gtaatattca
    10801 ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct tgagcaatat
    10861 aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata tagatggaaa
    10921 aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa gttgttcatt
    10981 gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt cgctatctgt
    11041 ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag aaaaaatgag
    11101 attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag gcacagagct
    11161 gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg cgttcacttc
    11221 tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa tttggcgtgc
    11281 accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat atgctgaaat
    11341 gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc tgatcgaaac
    11401 gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca tacagttgaa
    11461 aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc cgatttttcc
    11521 agatttccct cgctttggga tggactggcc gttgaatgat actttttcga aggtttctta
    11581 ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga tgtttggtat
    11641 ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag aatatggtaa
    11701 ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca tgacggttta
    11761 tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg aaaagtcaca
    11821 ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata aacaaaatgg
    11881 tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta tggaagatac
    11941 ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga aacaaagatc
    12001 aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa ccattgctta
    12061 aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg tttcgaacag
    12121 ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca gctcataaat
    12181 gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca tttgaaaaat
    12241 gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc agcaaacctt
    12301 cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt aggagatcaa
    12361 ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg aggaatcatt
    12421 gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt ttcatatatg
    12481 aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt attacgtaaa
    12541 aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct tttatctgct
    12601 gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga tattgatatt
    12661 acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat tgagcttggc
    12721 gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg tgctgctaaa
    12781 cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt agaggaatat
    12841 cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata tgataatcgt
    12901 catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt accgttcttt
    12961 tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca ggaaatggct
    13021 tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga ttatttagag
    13081 gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct ttctaaggag
    13141 agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc ttcaaagttt
    13201 acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc tttggaaact
    13261 tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta tcttacctta
    13321 accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga attactgcta
    13381 gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc agtaaaatgg
    13441 atccagcaag aacaacatac atctagattg agaacagaat tggagccttg gttacaagca
    13501 atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc aaaagaagca
    13561 gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt aactgcccat
    13621 ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa aaaggagaac
    13681 aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat gacgtcaaaa
    13741 gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga aacggttgct
    13801 aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc atttggtgca
    13861 gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg actaccaaat
    13921 gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat tcctaaatta
    13981 aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc taaaacaaat
    14041 atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga aacgatacaa
    14101 aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg cactggagta
    14161 accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc gggattgatt
    14221 attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa agaggcgatt
    14281 atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg gtctatccca
    14341 ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata tgatttgtta
    14401 acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt gcggcaatta
    14461 gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc tggatacggg
    14521 ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg aatgcgacat
    14581 accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa aaatggttaa
    14641 attgattatt taagtgggaa catacttgag atatcagcta acttctgtca ctttaaaaaa
    14701 gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact aggatagcag
    14761 aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct cttattgttc
    14821 ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta ggaaaaatgg
    14881 tagggaacca tatcattttt aatgaaaatc aagcatttca aaagt
//
LOCUS       DAFTHM010000063        14622 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFTHM010000063 DAFTHM010000000
VERSION     DAFTHM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.063"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..653
                     /gene="purM"
                     /locus_tag="L7C88_001882"
     CDS             <1..653
                     /gene="purM"
                     /locus_tag="L7C88_001882"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBP9558697.1"
                     /translation="MALIGGETAEMPGMYSGNDYDLAGFAVGIAEKSQLLTGETINPG
                     DVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLGEELLEPTKIYVSSLL
                     PLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPILPIFGCLQKYGEIPEM
                     EMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGKVIAKEKHRVVFIGEER"
     gene            650..1228
                     /gene="purN"
                     /locus_tag="L7C88_001883"
     CDS             650..1228
                     /gene="purN"
                     /locus_tag="L7C88_001883"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBP9558698.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            1225..2760
                     /gene="purH"
                     /locus_tag="L7C88_001884"
     CDS             1225..2760
                     /gene="purH"
                     /locus_tag="L7C88_001884"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBP9558699.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            2776..4050
                     /gene="purD"
                     /locus_tag="L7C88_001885"
     CDS             2776..4050
                     /gene="purD"
                     /locus_tag="L7C88_001885"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBP9558700.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            4172..5086
                     /locus_tag="L7C88_001886"
     CDS             4172..5086
                     /locus_tag="L7C88_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBP9558701.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(5219..6784)
                     /locus_tag="L7C88_001887"
     CDS             complement(5219..6784)
                     /locus_tag="L7C88_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBP9558702.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(6777..8228)
                     /locus_tag="L7C88_001888"
     CDS             complement(6777..8228)
                     /locus_tag="L7C88_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBP9558703.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITA
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(8242..9258)
                     /locus_tag="L7C88_001889"
     CDS             complement(8242..9258)
                     /locus_tag="L7C88_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBP9558704.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            9478..10566
                     /locus_tag="L7C88_001890"
     CDS             9478..10566
                     /locus_tag="L7C88_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBP9558705.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            10620..12146
                     /locus_tag="L7C88_001891"
     CDS             10620..12146
                     /locus_tag="L7C88_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBP9558706.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            12148..13353
                     /locus_tag="L7C88_001892"
     CDS             12148..13353
                     /locus_tag="L7C88_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9558707.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            13610..14587
                     /gene="guaC"
                     /locus_tag="L7C88_001893"
     CDS             13610..14587
                     /gene="guaC"
                     /locus_tag="L7C88_001893"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBP9558708.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
BASE COUNT         4643 a         2486 c         3280 g         4213 t
ORIGIN      
        1 atatggcgct gattggcgga gaaacagctg aaatgcctgg tatgtactca ggtaatgatt
       61 atgatctagc cggatttgct gtagggatag ctgaaaaatc tcaattattg acaggagaaa
      121 cgatcaaccc aggagatgtg ttgcttggaa tagcatctag cgggattcat tcaaatgggt
      181 actctcttgt tcgcaaaatt ttctttgagc agcagcagtt ttctttatca tcaaaactgc
      241 cagaattgaa aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc tatgtttctt
      301 ccttgcttcc gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc actggtggag
      361 ggtttgtaga aaatatcccg cgaatgttac cagaatctat ggctgcacaa atcaaacttg
      421 gctcatggcc gattcttcca atattcggct gtttacaaaa atatggtgaa attcctgaga
      481 tggagatgta tgaaatcttc aatatgggca tcggtatggt cctggcagtc gaagaatcga
      541 aagtaaaaga aatagtacac gaaattgagc aagctggcga aaaagtttat gaaatcggga
      601 aagtgatcgc caaagaaaaa catcgtgtgg tgtttatagg agaagaacga tgagaatcgc
      661 tgtttttgct tctggaaacg gaagcaactt tcaagcgcta gccgattatc tatcgaaaaa
      721 aggattggaa tcttcgattg actggttgtt ttgtgatcag cctgaagcat atgttttgaa
      781 acgtgcaact gcgttgagtg taccggcaga ttgtttttca cctaaagaat ttgattcaaa
      841 aaaagagtat gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg atttgatcgt
      901 attagctgga tatatgcgaa tcattggacc ggtattgctg aaaaattatg ataaaagaat
      961 catcaatatc catccgtctc ttttacctgc cttccctggt ttgcatggca tacgtgatgc
     1021 ctttgaagct ggagtaaaag aaacgggtgt cacaattcat tatatcgacc aaggtgtaga
     1081 tactggacca atcatccggc aggaaaaagt gagaattgaa caggaggaca cgttcgattc
     1141 tttagaagaa aaaatccata gagtagagca tcgaatctat ccagaagtga ttagtgaaat
     1201 tattgaaaat ggaggctatc tgaaatgaca agagcattga tcagtgtatc agataaaact
     1261 gggattgtag cattcgccca aggtttgatt gaacaaggag tagaaatcat ttcaacagga
     1321 ggaacaaagc atgcgttgga taaagctggg atcaaaacgc tttcgatcga agaagtgaca
     1381 gggtttcctg aaatgatgga tggccgtgtc aaaacacttc atcctaaaat ccatggtggt
     1441 cttttaggaa gacgcgatct ccctagccat atggaggcaa tggaaacgga aaatatccaa
     1501 ccaatcgact ttgtttgtgt caatttatat cctttcaaag aaacgattat gaaaccagat
     1561 gtcgaaatag cagaagctat tgaaaacatt gatatcggtg gtcctagtat gctccgtagt
     1621 gcagcaaaaa accatgaatt tgtcacctct gttgttgatc catctgacta tgaagaagta
     1681 ctttcagaat tacgtcagta tgggcatact tcactttctt tcagacaaaa actagcggca
     1741 aaagtctttc gtcatactgc ggcatatgat gcactgatcg ctcaatactt aacggattgg
     1801 gtggaagaaa aagaaccgga aaaattgaca cttacgtatg aacgaaaaca aacgcttcgt
     1861 tacggtgaaa atagccatca agccgctgcc ttttatcagt ccgctcttct ggaaaaatat
     1921 tcgatcgcag cagcaaaaca actccatggg aaagaacttt cttataataa tatccgagat
     1981 gcagatgctg cgctacggat catgaaggaa tatgacgagc caacggtagt cgccttgaaa
     2041 cacatgaatc cttgtggtat tgggacagca tctacgattt tagaagcgtg ggaagcagcg
     2101 tatgaagcag atcctgtttc aatctttggt gggatcatcg ttttgaatcg agaagtagat
     2161 ctgccaacag cagaacagat gcataagctg tttctagaaa tcatcattgc cccttcttat
     2221 acacaagaag ctttggaatt actgcaaaaa aagaaaaaca tccgattact gacagtagac
     2281 tttgcgcagg aagaaaatca aaatcgagaa gaaacggtct cagtcttagg tggacttctt
     2341 gtacaagatc aagatctggc aatagaaaat gaagaagagt ggaaagtcgt gacaaaacgt
     2401 aagccgactc cagcagaagc aaaagcatta gcgtttgctt ggagagctgt caaacatgtg
     2461 aaatctaatg cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg agccgggcag
     2521 atgaatcgag tcggttcagt aaaaattgcg attgaacaag cgcaagagaa aatggaaggt
     2581 gcagttttag ctagcgatgc ttattttcca atggatgatt cggttgaata tgcagccaaa
     2641 catggtataa aagcaatcat tcagccagga ggaagcatca aagaccaaga ttctattgat
     2701 atggcgaata aatacgatct agcaatggtc tttactgatg ttcggcattt tagacattag
     2761 agaggagtcg gataaatgaa cattttggtg atcggtgcag gtggtcgtga acatgcaata
     2821 agtaaaaaac ttttagccag tccgaaggtg gatacggtgt attgtgcgcc aggaaatccg
     2881 gggatgacaa aagatggtat caattgtgtc gctatcagtg agcgagatca ttcagcgtta
     2941 atccattttg ttaagaaaga ggctattgat tggagtatcg ttggtcctga agttcctttg
     3001 ttaaatggga tcgtcgatga ttttatggcg gaaggattga aaatcttcgg tccgacaaaa
     3061 gcagcagctc tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga tacttatcaa
     3121 atcccgacag ctaaatccag aagttttgaa tgttacgaaa aagcagcagc gtatatcaaa
     3181 gaaaatggtg cgccaatcgt agtgaaagcg gacggcttag cagctgggaa aggtgtagtc
     3241 gtggctacca cagtgaagga agcgctggat gcggcagaac aaatgttgaa ccagcatcga
     3301 tttggggata gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga agaattctcc
     3361 cttttggcgt ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca agatcataag
     3421 cgggcatttg ataacgataa agggccaaat acaggcggaa tgggtgctta ttcaccagta
     3481 ccgcaaattt caaaaaagat gattgaaaaa gctgtggaag aagttttaaa accagcggct
     3541 ttgggaatga aagaactagg acgctctttc acgggtgttt tatatgcggg tttgattgct
     3601 acgaaggaag gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc tgaaacgcaa
     3661 gtcgttcttt ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt attagagaat
     3721 cgtacagtag agttaaagtg gcagcaagaa ggatacaatg taggcgttgt ggttgcagct
     3781 gccggttacc ccgaagaata tgagacagga atggttctac cagattttct ggaagaagag
     3841 ctttctgttt actatgctgg agtttcctca aataacggca aactagttgg agcaggagga
     3901 cgtctttatt tagtagaagc atacggtgag acgatcaaag aagcacagaa aaaaatttac
     3961 accgcgttaa tggataaaac gacagatgga acattttatc gtacagatat tggagaaaaa
     4021 gctgccaata gcgaactgat cgtgaagtaa atcagctgct tccatttata aaaaatacaa
     4081 caaacataat cggaagcgcc gattttagtg aagccttttc ataaagagtg tggtacactt
     4141 ttgttgtgta tataaataag gaggagttca gatgaaaaaa attcaattag gtacttctga
     4201 tcagaaagca gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg aagatccagt
     4261 aaaagtgatt gagacagctt atgaaaacgg cattgatttt tttgaccatg cagatattta
     4321 tggaaacggt gaatgtgaag aaatctttgc agatgctcta gcaaaaacat caatcaaacg
     4381 agaagatctt tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt ttgatttttc
     4441 taaaaaacat atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa tggattatgt
     4501 ggatgcttta cttcttcatc gtccagatac attggtagaa ccagaggaag tagctgaagc
     4561 gtttgatgaa ttggaacggt caggaaaagt tcgttatttt ggcgtcagca atcaaaaacc
     4621 aatgcaaatc gaattgctga aaaaatatgt tcgtcaacca ttagtagcta atcagctgca
     4681 atttggcttg aaacatactg gaatgatcga tcaagggatt catgtcaata tgacagatga
     4741 agcaagtatc gatcatgacg gtagtgtact tgattattcc cgattgcatg atatgacgat
     4801 ccaagcatgg tcaccatacc agtatggatt ttttgaaggt gtatttatcg ggaacgaaaa
     4861 attccctgaa ttaaaccaaa cattagaaga actagcagct aaatatcaaa cgacaccaac
     4921 tggcttggct tctgcttgga ttttacgcca tccagccaat atgcaagtga tcgccggtac
     4981 gatgaacgta gggcgaatca aggaaatcgc tcaagcttca gaaattaata tgtctcggga
     5041 agattggtac gaattgtacc gtgctgctgg aaacatttta ccttaaagat tgtcataagc
     5101 aggtcaaaag ggctataaat taaaaagaca gaataacttg aaagctgttt tcagcttcga
     5161 gatattctgt ctttttttat tgcaaatgga aagagtatca ttgtacggat ttcgtttatt
     5221 agttattttt gtttttaagg aaaagctgtg tccgatattc ttttggagaa atcccttgtt
     5281 ttttcttaaa taaataactg aaatagttag ggtcattata accaatttca aaagcaatat
     5341 ctgaaatacg atagtctgat tgctgcaata atttttttgc taattcgatt ctttgttctg
     5401 tcagataatc gatgaatgtt tggttaaacg attgagaaaa aatcgtactg aaatgagagg
     5461 gacttaatgc aacttgttga gcgacccaag ttaaggacat atctggatcg gtaaaatttt
     5521 ctttgataaa atccaatgca tggttcaaaa ttggctgata tttgttcctt gaaggctgtg
     5581 agggcagagc agttaagaaa gaaatgaaca tataaactgt cgaacggtaa agcgagtcgt
     5641 cggcgctgat tgctaagcgt tgactggtgg atgtgcaatg aaccatttct tgcgggattt
     5701 tcttttcttt caggcagaca tgctggagta gcttagtcaa gacaaataaa cgatataatc
     5761 gtgttcgagt tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta gatacttcgt
     5821 ttttcgataa tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa tcaactggaa
     5881 gtttcgcttc ttgaatcaaa tcctcatagc tgataatttg ttctttaagg gaactggcgg
     5941 tttcaagtat catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt ctttctgcga
     6001 caggaccaat ggcgacagaa aaattatttt tttgtccctt ttctaattca tggaccaacg
     6061 tttgggctac ctgataactg gtctcgatca cattttcttc aagagaatca actattaaaa
     6121 atttgatgaa tcgagaggaa acagcagaga agatcacttg ttgattctcc ctaaataaaa
     6181 acttcaaata atcactgaga tgagcgtaat cttcaaagtc tgtactgact tggtttgctg
     6241 ctaataatac ggtcattttt ttccctgcta aagagcgatt gaaagattca gcaagtttca
     6301 atgtttcact gatcgtaagt gagcctttga acaaaccgtt caagaaatga ttttttttca
     6361 attcgaaaac aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct aaagcagtta
     6421 ctgctttttc tattgcttgt ttcaattcgc tacttttaat cggtttaagc agataatcat
     6481 ctgcctgtac ctggattgct cctttcatat aatcgaaatc gtcgaatcca ctaataaata
     6541 tgagacgagt ccaaggaagt agtttccttg cttcttttga aaaagtcaac ccgtccatga
     6601 aaggcatttg gatatcagtc agaatgatgt cgggctgtaa gtcgataatt gaagacagtg
     6661 ccatctcacc atctccagct tcgccgacat aagtgattgg ataataagaa ccaaggacag
     6721 ttatttgttc ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata aaaactttat
     6781 acatgtttgt ttcctccaat tgttttggga gatagaggga tcatcagtgt gacagttgtt
     6841 ccttctcggt atttgctgtc aatcgtgata ggtttttgat catttccgta ataaagaagg
     6901 agacgcttgt ttacgttgta aagtccgtag ccgatactga aatctgaatc gatccctttg
     6961 gctaactctt tacgtatttc tgccagtttt tctgcaggga tgccaatccc gttgtctata
     7021 actttgaatt ggatcatctc atcaattttg catgcggtaa tacgaataaa tcctttgtga
     7081 cggacgtact tcgttccatg gtatacagca ttttcaatca atggctgcaa gatcattttt
     7141 aaaatagaaa caggaaaaag tgtttctggt atatcgatct tatagtcaag catatggccg
     7201 tatcttattt ttaagatgac tagataatca ttgatatggc taatttcttt ttcaagagga
     7261 atccagtctt gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc atgggtcata
     7321 gtcagagctt cttcaaagca gtcttgttcg atcaaagaaa taatggcatc caaactgtta
     7381 taaataaaat ggggagtaat ctgagcttgc aatacacgaa cttcactttg tgctaaatgg
     7441 tattgtttca aagcgttctc ccgtaaagac tggtttagat cttccgccat tttattcatg
     7501 ctagcggtaa gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa gccaaggttc
     7561 cctgaagaaa gttgttctga catctcgatc agctgattga tcggttcttg gacctttctc
     7621 tctaaaaagc gacgattctt tttcgcatag aaaaaaatgg tactaagaac tccaagttcc
     7681 actattgtta atagaatgag cgagcggaca agtgtcgtat tttttttgct tgctaagtcg
     7741 atctccacac gaacaaaatc ttgtaagata tctgacagca gttgagtgac agaatctacc
     7801 tgattgatga tctcttcatt ggtatccata aaatcttttg ccaagatatt attgatcagc
     7861 tcgttttgat aatcttccag tgtatcgatc gtacgtagcg atacatctaa cgtactaatt
     7921 tctttaagtg tatttgtatt atttttgatc tctcgaatat cattcctaag ttcttctagg
     7981 atattttcct cattgaactc atctacggtt acttggccag aaatcaagtc ccacatactt
     8041 tccaaaactt tttgatcaac cttcaaagca attgcatctg ctttttggat atttgcgatc
     8101 gtctgttgat aaatcaaaag ctgttgcgaa tataacagta tgctcagtag caaagggata
     8161 acagcaaata gaagcatggc tttgtttgct tgggcaaaaa tctgttttat gcttaaattt
     8221 tttgtcatga tacttctcca gtcaataatt tctggttggg atgttagcta tattctgctg
     8281 ggaaaagaca gtctcggaaa taaaaatatc tttaggtaat gtttttcctg tttgaatatt
     8341 tccaaaataa cgagtaacgg tattggctac ataccagccg acatcaggtt tacactcgac
     8401 tacacaattg acgattcctg agcgtagctt ctcgatcata tcttcttgtc catcaatagt
     8461 tacaatgatc aaatcttctc caggtttgat tgatgtttct tttatcgcag ctaaagcacc
     8521 gtgagtcatt tcatcactat ggctgtataa tacatcgatt tcggataaat catttgtttc
     8581 taaatatcgt ttcatctggt cttttccttt catccgaata aaatcaccga caattcggtg
     8641 aacaatagtc atcggaggtt tatggtcgat ggttccatct ttttttaggg ttggtttacg
     8701 attgattgat tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt tctctgaacc
     8761 agcaagttct aggattctga tttcctgttt ctttgaattt gtgaagtgat tgctgacaaa
     8821 taaacccgcc cgatttcctt ctgctttgaa actggggcca atgtgggtga cgaaaagctc
     8881 gggatcattc gtttgaatat gtctgtcgac aagtatgaca gggatccctg ctcgctttgc
     8941 ttcttttaat acagagtccc acccggattc ttgcaaagga gtaaaaatga tcatatccac
     9001 tttataggca atgaacgtcc gtatatcttg gatttgccgt tcctgattca tgtagccatt
     9061 tcggtagaga acttggtaat cttctttttc aagcgcagtg ataattgatt cagtatgctt
     9121 tttccgccag ctactctccg ttcctgattg cgaaaaacca acgactagtg ggtcaggtgc
     9181 ttcctttgta ttaggtgtac accccatcat ttggtaagcg attacaacaa gggctaaaaa
     9241 aaataaaaca cgtttcactt taaatcactc catctggatt tgttagtact atcttatcag
     9301 ataaaaggga aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga aacttaaaaa
     9361 aatccaagac aaaaaaagta cacctaaaaa atttaaagta aatcccataa aaaaatcaat
     9421 gttaacgctt tctttattag ctatactcgg tgtatcaatt gaaatggggg ataaaaaatg
     9481 aaaaacaaat ttagaaagat tgttgggact atcgctattt tgaccgcaag cattctatta
     9541 agtgcgtgtg gcaattcagg atctgcagat gatagtacgg ggtatgtagg aatcgctatg
     9601 ccgaccaaat cagcagaaag atggatcgct gatgggaaca acatggtctc ggaattagaa
     9661 aaactgggtt ataaaacaga tcttcaatat ggagaagata aagtagaaaa tcaagtagca
     9721 caaatagaaa atatgattac aaaaggggta gatacacttg tgattgcttc tatcgatggt
     9781 tcggctttaa ctgatgtgtt agctaaagca aaagaagcag atatcaaggt gatcgcctat
     9841 gatcgtttac tgatgaattc agaaaatgtc gattattacg cgacttttga taattttgga
     9901 gtaggtgtat cgcaagcagc ttatattgaa gagcacttag gattgaaaga aggaaaagga
     9961 ccattcacga ttgaattatt tggtggctcg cctgacgaca acaacgcact aatcaattac
    10021 aacggagtga tgtctgtttt acaaccatat atggacaacg gtcagttggt cgtgccatct
    10081 ggacagacga gtttcagtca aatcgctacg cttcgctggg atggttctac ggcgcaagca
    10141 aggatggata atctgttaag cgcaaattat actgaccaaa cattggatgc tgttttgtcg
    10201 ccatatgatc caataagttt aggaatcatt tcgtcattaa aaggcgtggg gtatgggagt
    10261 gaaagtaaac ctttacctgt gattactgga caagatgcga cagttgctgg cgttaaatcg
    10321 atcattgccg gggaacaaac acaaacgatc tttaaagaca cacgtatctt agcaaaaaat
    10381 acgattgaaa tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa tgatactgaa
    10441 acttatgata atggggtgaa aactgtccct acgtatttag caaatacagt atctgtcgat
    10501 aaagataatt atcaagcaga gctgatcgac accgattatt ataaagaatc cgatctgaaa
    10561 aattaagagg aaccaaacaa ggaactaaag agatctaagt cagagagagg ataagaatta
    10621 tggcggattg tattttaaaa atggcagata tcaccaaaaa attttctgga atccgagcgt
    10681 tagattgcgt gaatctgatg attgaacgtg gggaaatcca tgcattgtgc ggagaaaacg
    10741 gagcgggaaa atcaacattg atgaatgtct tgagcggctt gtatccatat ggctcctatg
    10801 acggggaaat cttttatgat ggaaagctgt gtcaatttaa agatttgaaa gatagtgaag
    10861 aaaaaggcat cgtcatcatt catcaagaat tagcactaag tccttatctt tcaataaaag
    10921 agaatatttt tctcggaaat gaacaagcag aaagaggcgt gattgattgg gaactgacag
    10981 aaaagaaaac atatgaactg ctgaataaag tcggtttgtc tatcgacccg aatcttctag
    11041 tatcccagat tggcgtaggg caacagcaac tagttgaaat agctaaagca ttatcaaaat
    11101 ccgtccgtct gttgattttg gatgagccta ccgctgcatt gaatgaagaa gaaagcgcga
    11161 atttgctgag attgatccga gagttgaaag agcaaggtgt aacctccatc attatttcac
    11221 ataagctgaa tgaaatcgtg gatatcgcag atcgaatcac cattttacgg gatggacaga
    11281 cgattgagac actagaaaat gaaatgatca gcgaagagca tattattcgc gggatggtgg
    11341 gcagagattt agttgatcgt tatcctgaaa gaaaaccgga tattggagaa gtttatttta
    11401 aagtagaaga ctggacggtc tatcaccctc ttgatcacga gcgaatcata aacgaccaca
    11461 tcaacttgca tttgaaaaaa ggagagattg taggaatagc tggactgatg ggagcgggca
    11521 gaactgaatt cgctatgagt ctatttggac attcttatgg aagcaagata tccggacgta
    11581 tattaaagga aggggcagag atatcagtta agaccgttcc ttcagccatt gcaaacggac
    11641 tcgcttatgt ctcggaggac cgaaaatctt taggactgaa tctgctgatg gatattcggg
    11701 aaaacgtgac gctgagcagt ttggataaaa taagtcaaaa aggagtatta gataaagaaa
    11761 aagaagtaac tgaggcagaa aatttccgga aaaagatgcg tataaaaaca aactccatcc
    11821 atcaaattgt cagtagtctt agtggtggga atcaacaaaa agtcgtttta tccaagtggc
    11881 tgatgacaca acccgatatt ctttttttgg atgagccaac ccgtgggata gatgttgggg
    11941 caaaatatga gatctacacg attatcgaag aaatggcagc aaatggcaaa gctgtctgtc
    12001 ttatctcttc tgaacttcct gaaatattag ggatgtgtga tcgaatctat acgatgaacg
    12061 aaggacgtat tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc ttgatgaaat
    12121 taatgacgaa agaagaggtg ggttaagttg gaacaggcaa aaaatcttac ggataaaaaa
    12181 gagaaaaaac taaatttgaa aagtagagca gctgatcttt ttggtcgcta cagcatggtg
    12241 atcattttag cgggactact tattgcgttt caattgatga cggatggtat tttctggcgt
    12301 ccattgaata taactaacct tgttctgcaa aatagccata tattagtact agctgcaggg
    12361 atgttattag ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt gatggcgttt
    12421 gttggtgcaa ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg gatgacagtt
    12481 atcgcatgtc ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg ggtagcttat
    12541 gcagggatac cggcgtttat cgtgacttta gcaggattgc tgatgtttcg tggactgaca
    12601 caagttgttc taggaggcca atctctagca ccttttccag ctgttttcca aaaaatgtct
    12661 acgggttatt taccagactt aagcgaagga agcagccttc acttcttgac attgatttta
    12721 ggaatgatca tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa tcgtcggaaa
    12781 aatcatttat ttgaagtgga atctccaaca gctttcttgg taaaggcggt atttacagca
    12841 gtcgttgtac taggaataac ttatatcttt gcctcttatc aagggtatcc gattattttg
    12901 atcattcttg gtttgatcgt tgcagcatat gggtttttga caaataaaac agtagcaggt
    12961 cgacagattt atgcgacggg cggaaatcga aaagcggctg aactatcagg gatcaaaaca
    13021 aagcgaatca cgttctgggt attcgtcaac atgggagtca tggcagcttt agctggatta
    13081 gttttagctg ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat ggaactggat
    13141 gcaatggcgg cagtatattt tggtggtgct tcgacttccg gcggcattgg aacaatcatg
    13201 ggtgcgattg tcggtggctt ggtcatgggt gtattgaaca atggcatgtc gattttaggc
    13261 gtcggggtag actggcagca ggcaatcaaa ggattgatct tgcttttagc cgttgtgcta
    13321 gacttgtata ataagaaaaa acgaacaacg taggagaacg ccggttattc agaaaaaaga
    13381 ctgtgacaag acatttgtca cagtcttttt ttcgctaaaa gcgaacattc attgtttcgt
    13441 ttgtatagac taaaaataat atatgttttt ttaccattcg tataaattct ctttttgctc
    13501 ttgatttttt tgcttaattg agttaaatta catagggcgc taaaaaaagc cttgattaaa
    13561 ttaataatgt tcgtgttttg ctggatgtga acatcaggag gataatgtaa tgaaagtatt
    13621 tgattacgaa gatattcaat taattcctaa taaatgtatc gtaaatagcc gttctgaatg
    13681 tgatacaacg gtcacattag gtaaacatac attcaaaatg ccagtagtgc ctgccaacat
    13741 gcagacgatt attgatgaaa caatcgcaga attcttagcg gaaaatggtt atttctatat
    13801 catgcatcgg tttgatgaag cagctcgaat tccgtttatc aaaaaaatga aaaagcgtgg
    13861 attgattacc tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta tagagaagtt
    13921 ggcagaagaa tcgctaaatc ctgattatat cactatcgac atcgcgcatg gacatgctaa
    13981 ctcagttatt gatatgattc agcatattaa aaaatatttg cctgaaactt ttgtgattgc
    14041 cggtaatgtt ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg cagatgcaac
    14101 aaaagtcggg attggtccag gaaaagtatg tattacaaaa atcaagacag gctttgggac
    14161 tggaggctgg caactggcag ctcttagatg gtgtgcgaaa gcagctcgca agccgatcat
    14221 cgctgacggt gggatcagaa cacatggcga tattgcaaaa tctgtccgtt ttggtgcgac
    14281 aatggtcatg attggttcat tgtttgccgg tcacgaggaa tctcctggcg aaacaaaagt
    14341 cgaaaatgga atcgtgtata aagaatactt tggttctgct tcagaattcc aaaaaggcga
    14401 aaaacgaaat gttgaaggaa agaaaatctg gatccaacac aaaggatctt tgaaagatac
    14461 actagtggaa atgcaacaag accttcaatc atctatttct tatgctggag gaagagatct
    14521 ggaagccatt cgaaaagttg actatgtcat cgtgaaaaat tcgattttta atggagacac
    14581 aatctaaaaa ataaataaaa tattaggatg ttgtgaaaaa gt
//
LOCUS       DAFTHM010000064        14515 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFTHM010000064 DAFTHM010000000
VERSION     DAFTHM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14515
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.064"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(320..682)
                     /locus_tag="L7C88_001894"
     CDS             complement(320..682)
                     /locus_tag="L7C88_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558709.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(756..1136)
                     /locus_tag="L7C88_001895"
     CDS             complement(756..1136)
                     /locus_tag="L7C88_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBP9558710.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1200..2393
                     /locus_tag="L7C88_001896"
     CDS             1200..2393
                     /locus_tag="L7C88_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBP9558711.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2470..3054)
                     /locus_tag="L7C88_001897"
     CDS             complement(2470..3054)
                     /locus_tag="L7C88_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBP9558712.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3255..4253
                     /locus_tag="L7C88_001898"
     CDS             3255..4253
                     /locus_tag="L7C88_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBP9558713.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4365..4874
                     /locus_tag="L7C88_001899"
     CDS             4365..4874
                     /locus_tag="L7C88_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBP9558714.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4904..5563)
                     /locus_tag="L7C88_001900"
     CDS             complement(4904..5563)
                     /locus_tag="L7C88_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBP9558715.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5565..6329)
                     /locus_tag="L7C88_001901"
     CDS             complement(5565..6329)
                     /locus_tag="L7C88_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBP9558716.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6337..7014)
                     /locus_tag="L7C88_001902"
     CDS             complement(6337..7014)
                     /locus_tag="L7C88_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBP9558717.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7051..8436)
                     /locus_tag="L7C88_001903"
     CDS             complement(7051..8436)
                     /locus_tag="L7C88_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBP9558718.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8646..8730)
                     /gene="ffs"
                     /locus_tag="L7C88_001904"
     ncRNA           complement(8646..8730)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="L7C88_001904"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8753..9268)
                     /gene="tadA"
                     /locus_tag="L7C88_001905"
     CDS             complement(8753..9268)
                     /gene="tadA"
                     /locus_tag="L7C88_001905"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBP9558719.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9375..10232
                     /locus_tag="L7C88_001906"
     CDS             9375..10232
                     /locus_tag="L7C88_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558720.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10313..10648)
                     /locus_tag="L7C88_001907"
     CDS             complement(10313..10648)
                     /locus_tag="L7C88_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558721.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10715..12085)
                     /locus_tag="L7C88_001908"
     CDS             complement(10715..12085)
                     /locus_tag="L7C88_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBP9558722.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12163..12699)
                     /locus_tag="L7C88_001909"
     CDS             complement(12163..12699)
                     /locus_tag="L7C88_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBP9558723.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13008..14489
                     /locus_tag="L7C88_001910"
     CDS             13008..14489
                     /locus_tag="L7C88_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558724.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         4472 a         2889 c         2357 g         4797 t
ORIGIN      
        1 cttatcatgt cgttagtaac atgtcaataa ctatttttta aattttttag aaatgtgata
       61 taacatccac ttcagaatca acgctgttaa atttatcatg tatttcttcc ttggtcaact
      121 ataaattaag cattactttg tgaaatgatt tttcgatcaa ttattattat tcgttataca
      181 accgttttca acatattttg aaaataaaat gcactaaaaa actatcttta gcagaacatt
      241 tcattgtatt ttttggacca aacaataaaa aaagaagttt gaaaaaaatt caaacttctt
      301 tgttcgctta atctgtattt tagaagaaag gcactccctc tacttcgtaa gttccaagaa
      361 cagagcgcat ttgacctggt tcttcccaaa tatatccttc gcctaattct tctctttgat
      421 tcttttgttc agtttcaaag acaaacaacg gaacattttc ctctttaata tgtgtatttg
      481 tcaattccat caaactaatc ttgctaacat cgatatgaac tatttctttt aagaaattaa
      541 gtatattcgc taaaccagtc tttccttcag aaagttccgc taacgcaaat tccaacttgt
      601 catcaattga atggaccaaa aattttttag taccatcctc caaatgcaac ataattgtac
      661 cagcaactct tttgcttgcc aaaatttcca cctcgatcaa cttgttctat ggcttacata
      721 aaaattctag cacattttca gaaaaaatac actttttatt tcttattttc tttccgttct
      781 agttcagata atgcttcttc tatccaaata ggtaactgct ccgcaatagt ggtaaatccg
      841 atcttacgat ttttattcgt gaaatacctt tttctgcgat atggaacagc tggatttgtt
      901 ttttctaacg ttcttaaaga taaactgatt tttttggaat attcatcaat gtcgatgatc
      961 tgaactgtta ctggctgtcc gacttttaac aatgaatgga tatttttcgt ataaccggat
     1021 tgtacttctg aaacatgaat aagtccttgc gtctcgttat caagagaaac gaatgcgcca
     1081 taaggctgta tccctgtcac ttttccttca attatttgtc caattttata agtcatctac
     1141 ttccctctct tcgcatttat cattatactg taaatagctc aaaaaaagaa gcgacgaaaa
     1201 tgactggagg tcttaagatg atcgaatttg ataaacagat ttcaagaaaa gatacagaaa
     1261 gtgtaaaatg ggacgcaatt gctgagacat atcaaatgga tgacttactt cctttgtggg
     1321 tagcagatat ggacttcttg tctcccggtg gggtagctaa agcgtttagt gaatacatca
     1381 aacatggaat ctttggttat gccactctgt ctgataaact atatcaggct atcattcatt
     1441 gggaacgcca acaccatgct gtggagttga cgaaagaaaa tatcgttttt acaagtggtg
     1501 tgttaaccag tttagctgca gcagtacaaa cttttacaaa accaggcgat tctattttga
     1561 ttcatgaccc agtttatcct ccattttcct ctattataga aacaaatcaa cgtcacatcg
     1621 ttcgaagctc tttgctagaa aaaaataatc atttcatcat ggacttgtct gacatggaga
     1681 aaaaaatcga agaaaacaat gtaaaagcaa tgattttatg caatcctcac aatcctggag
     1741 ggcgtgtttg gagcaaagaa gaattgaaac agttaagcga attgtgttta aaacatcaag
     1801 tgattctgtt tagtgacgag atccatcaag atttaacttt attcgatcat acatttactt
     1861 ccatgctaac gattgatcct aatttagatg atctactagt tgcttttact tccgcaacca
     1921 agactttcaa tctagctgca atcaaaaatt caatggtatt tatcaaaaat ccagagatga
     1981 aagctgattt tgaaaaacat ttagtgatga accaacagca cgaaatcaac acttttggac
     2041 tgattggaac ccaagcggct tatgagacgg gtggagaatg gttaagccaa ctgattcctt
     2101 atctagaaaa aaatgttcaa acagttaatc agttttttga acagtatctt ccgaaagtga
     2161 gaataatgaa ccctgaagga acttacttaa tgtggttaga ttttaccgcc tatatttcag
     2221 acgaccaaga attggagaac actcttgttc ggaaaggaaa agtcgtatta aatcctggca
     2281 tcacgtttgg tccttccggt catgggcata tgcgcttgaa tattgcttgt ccagaagaaa
     2341 ctttactgga aggacttaat cgaatcaagt atgctttaga gacaatcgat taaatcattt
     2401 attcaaaata aaaggacgag accttactag gtttcgtcct ttttcataat tactccgtac
     2461 cataccaaac tattctgaaa tttcaattgt ttcaatcact acatcatgta caggtcggtc
     2521 ttgtggacca cgttgtacat ttgcgatttc atctactgtg tccatccctt ctagtacatg
     2581 tccaaagact gtatgtcgga aatctagcca aggagttccg ccacctttat acgcttcaat
     2641 gatttctgat gggaatccag caccttctag ttgtccaagc atattagctg gcacatttgt
     2701 gttatttaca ataaagaatt ggcttccgtt tgtgtttgga cctgaatttg ccatagataa
     2761 agctccgcga aggttgaaca gttcacgact gaattcatct tcaaaacttt cgccataaat
     2821 actttcgcca cccattcctg ttccagttgg atcgccgcct tggatcatga aatcaggaat
     2881 aacgcggtga aaaatcacgc catcataata accttttttg gaaagttcaa tgaaattttg
     2941 aaccgtcttc ggtgctagtt cagggaataa ttgaacagta atgtcaccac ggtttgtttt
     3001 gataacagct tttggtcctt tttcactttt taaatctagt tgtgggaatg ccatattgtt
     3061 tcctcctaat atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa
     3121 atactagatt tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc
     3181 gatttcgaat tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa
     3241 agggaggaat ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga
     3301 tgtttgccgc tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac
     3361 ctcaacttgg tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg
     3421 ggtatccagc aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt
     3481 ttaaccatac attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta
     3541 tcgagattac tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa
     3601 atggttcatt ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg
     3661 gattggatta tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg
     3721 gaggtggtga ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt
     3781 acttgattca tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat
     3841 cttcatctgt caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg
     3901 aactgacaga tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg
     3961 attctctgat cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac
     4021 ttgatagtac cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg
     4081 tttatgcagc tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc
     4141 tcggtgaagc acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa
     4201 ctcagcctgg tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta
     4261 tatctctttg catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg
     4321 ttaacatgaa atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg
     4381 agactttaga agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata
     4441 tcgcacaact tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt
     4501 gtactgaaag tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg
     4561 gaatccaatt agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta
     4621 tcgaagatga cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg
     4681 tttacggtac gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt
     4741 taaaagaact aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg
     4801 gagcgatcgc cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc
     4861 gccttactca ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct
     4921 tttttgtttg tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta
     4981 ataatacaaa aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga
     5041 ttggatcagt aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa
     5101 ggataaaaaa gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca
     5161 tgccgatttg aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga
     5221 taaacaaaat actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa
     5281 ttttcacttc ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga
     5341 ggatggtttt gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg
     5401 tctcttgatc taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata
     5461 gtggtcgaaa gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga
     5521 acaatccagc atattccatc cactgccatc tcgaattttt catattagaa gctccattca
     5581 tccagtgatt gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt
     5641 gtaaaacctg ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct
     5701 gtttcatagt tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg
     5761 gctttatcca taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct
     5821 gtctctacaa aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata
     5881 ttcttatctg ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta
     5941 actacttttt cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct
     6001 tcttcccatg taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca
     6061 tagacttttt tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg
     6121 tagactgtct ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt
     6181 tctggtgact tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat
     6241 tcttccacaa atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct
     6301 aaatcaatta aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt
     6361 aaatgctgtt tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga
     6421 ggtttttgct gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac
     6481 tggtcctttt ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg
     6541 agttgtcttt tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt
     6601 gcaatattcg taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg
     6661 attatccgct tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat
     6721 ataatcatat cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc
     6781 ttcacgataa tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc
     6841 taacagtgtc actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc
     6901 caaagcagct gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt
     6961 agcaatttct gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc
     7021 accacctatc ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta
     7081 atctcctacc acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc
     7141 aatcgttgga aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt
     7201 attcagatcg attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat
     7261 tccattatag accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata
     7321 gttacgtaaa aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc
     7381 acccaatgtg acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg
     7441 attgacccgc ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc
     7501 cgtctttcct cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa
     7561 gatatctaga ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg
     7621 cccacgttct agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc
     7681 ggtagggatg gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg
     7741 gacttcaccg acatactgcc cgtactttcc agcggctgct atttggacat cattgattac
     7801 gtgaccttct ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat
     7861 ttcttttgca atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc
     7921 cacttgtgaa cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc
     7981 ccagccattc ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt
     8041 cgtctggtgt ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt
     8101 atttttatcg aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt
     8161 caactcttct ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc
     8221 aacttcattc atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca
     8281 acgatccaca aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt
     8341 ttctcgttta cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg
     8401 cagatcattc gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct
     8461 ttatcatacc ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc
     8521 tgccttgaag caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag
     8581 gaacattcat ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg
     8641 tttcattata atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac
     8701 acgcttcaca agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt
     8761 cattcgttga ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt
     8821 cagtcaaaat catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt
     8881 taaaccgctc gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat
     8941 acgcgccgaa ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac
     9001 aaggctctaa ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac
     9061 aggcttcctt gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa
     9121 ggttatatcc tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt
     9181 catgaagcat ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt
     9241 ctactgcatc aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt
     9301 tactttagca tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac
     9361 aagaggtgaa caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa
     9421 aaaactctcc agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct
     9481 ggatcaaaca agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg
     9541 taatcaacga tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg
     9601 ttcaagaaaa aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa
     9661 aaaaagaatg gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt
     9721 atacagacac agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg
     9781 aaatcaacgg tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg
     9841 ttggttcttt ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa
     9901 tttttttaac agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg
     9961 tggctttaca ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca
    10021 tagaactgat caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag
    10081 gcaatgtcag ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa
    10141 tcgaaaaatt tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt
    10201 gctatctttt attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa
    10261 ttttgtcaca accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca
    10321 ttttttcaac aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat
    10381 caccataaac agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag
    10441 aatccaagtc actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa
    10501 atttgtcata gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca
    10561 ttacttttcc cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc
    10621 cgattgttac ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca
    10681 tagcatagac aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga
    10741 aaaagttctt tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata
    10801 ctagcaaaac ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt
    10861 gccattcctt ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg
    10921 ctaatgcata gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac
    10981 gtacgacttt taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt
    11041 tgaacactaa aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga
    11101 gtttttcctg ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat
    11161 gcatctgatt ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt
    11221 tatgaggcca tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc
    11281 ctgaactaac ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa
    11341 gccagctaat gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt
    11401 gtcctttatt ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac
    11461 agtatagcgg agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc
    11521 cttctcctga acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga
    11581 caagttctgc gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat
    11641 tttctgataa aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc
    11701 ccttcatttg agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa
    11761 ctttttcacc gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc
    11821 tatattcata cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct
    11881 cattgctgta gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc
    11941 ctgccggttt tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag
    12001 aaaaaaaatc ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg
    12061 gtaacgttgt cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt
    12121 acgaaaaata aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt
    12181 taagatattt tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat
    12241 ttcaagaaaa tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac
    12301 caattcaagc gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg
    12361 ccgcttaaat agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc
    12421 atggatagaa aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca
    12481 ttcagctaag tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc
    12541 gctgattgat ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa
    12601 ctctcttgca gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag
    12661 caaatattct ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca
    12721 tctacccata aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca
    12781 tatttagtta tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca
    12841 aaatacccta ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta
    12901 tataaaaaag aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac
    12961 agtttttgtc taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag
    13021 caagaaaaaa agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac
    13081 aagaattatc caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa
    13141 taaatgtatc actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag
    13201 gagagatcca aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa
    13261 aattatgcta cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc
    13321 cacaaactgc tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc
    13381 tcgaaaaact gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat
    13441 ctgtaaaaaa ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact
    13501 tttttctttc agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg
    13561 cactaaaaat gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata
    13621 tctacttgct gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa
    13681 cttcttctga aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat
    13741 actttacttc tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact
    13801 ttaattattt tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga
    13861 ttggtttttt attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga
    13921 cttacttaac tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt
    13981 attttcttgt gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt
    14041 ctacactttg ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga
    14101 aattaagaga aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc
    14161 aataccttag tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca
    14221 tccatttgca gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc
    14281 agttatttcg caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca
    14341 ttacagatca gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc
    14401 acaatacagt gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag
    14461 gttatgagaa caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttatt
//
LOCUS       DAFTHM010000065        14496 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFTHM010000065 DAFTHM010000000
VERSION     DAFTHM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.065"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..196
                     /locus_tag="L7C88_001911"
     CDS             <1..196
                     /locus_tag="L7C88_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558725.1"
                     /translation="YPSILKITDLTKMLNIGKNKAYNLLKDRSIENIKIGARYKIPKK
                     AVIEYILKIQDEGKNHAIIK"
     gene            240..1409
                     /locus_tag="L7C88_001912"
     CDS             240..1409
                     /locus_tag="L7C88_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBP9558726.1"
                     /translation="MKLRANIIEKRGTLQVVVSYKDSNGKIRQKWKDTKLKKKGNKKR
                     AEKIRDEFLLELESQLAMECECANPNLLFYDYLLNYLEVSKKQVAFNTYVGYKHYVHN
                     RIYKFFYPKKIKLNRLKPYHLQEFYQYMLNDNCTANTVIHYHAFIRKALQEAVITELI
                     STNVADKVRKPKKKQFVSQVYNQQEILKLLDILSEEKLYLVVLLTAFYGLRRSEVLGL
                     KWSAIDFLNKKIMINHVIIENPENMSQLIKKDQTKNSSSYRTLPLVETIERALVNQAK
                     WQQDNRILLGDDYILEDNEYVFTMEDGRLMKPQYVTHRLSKLIKKNGLKKIRFHDLRH
                     SNASIMLDSGQNMKSIQEWLGHASYSTTANLYTHLTAGVKDRAAEALENAFGFKE"
     gene            1983..2552
                     /locus_tag="L7C88_001913"
     CDS             1983..2552
                     /locus_tag="L7C88_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBP9558727.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            2539..3399
                     /locus_tag="L7C88_001914"
     CDS             2539..3399
                     /locus_tag="L7C88_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBP9558728.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            3589..4293
                     /locus_tag="L7C88_001915"
     CDS             3589..4293
                     /locus_tag="L7C88_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9558729.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            4298..6133
                     /gene="walK"
                     /locus_tag="L7C88_001916"
     CDS             4298..6133
                     /gene="walK"
                     /locus_tag="L7C88_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBP9558730.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            6130..7446
                     /locus_tag="L7C88_001917"
     CDS             6130..7446
                     /locus_tag="L7C88_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558731.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            7447..8316
                     /locus_tag="L7C88_001918"
     CDS             7447..8316
                     /locus_tag="L7C88_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBP9558732.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            8371..9180
                     /locus_tag="L7C88_001919"
     CDS             8371..9180
                     /locus_tag="L7C88_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBP9558733.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(9283..9912)
                     /locus_tag="L7C88_001920"
     CDS             complement(9283..9912)
                     /locus_tag="L7C88_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBP9558734.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            10082..11374
                     /locus_tag="L7C88_001921"
     CDS             10082..11374
                     /locus_tag="L7C88_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9558735.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(11450..12112)
                     /locus_tag="L7C88_001922"
     CDS             complement(11450..12112)
                     /locus_tag="L7C88_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBP9558736.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            12337..12621
                     /gene="groES"
                     /locus_tag="L7C88_001923"
     CDS             12337..12621
                     /gene="groES"
                     /locus_tag="L7C88_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBP9558737.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            12672..14297
                     /gene="groL"
                     /locus_tag="L7C88_001924"
     CDS             12672..14297
                     /gene="groL"
                     /locus_tag="L7C88_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBP9558738.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4946 a         2414 c         3055 g         4081 t
ORIGIN      
        1 ttatccatcg atattgaaaa ttactgattt aactaaaatg ttaaatattg gaaaaaataa
       61 agcttataat ttgctgaaag atagatcaat agaaaatata aaaattggag caaggtacaa
      121 aatacctaaa aaagctgtca ttgagtatat attgaaaata caagatgaag gtaaaaatca
      181 tgctataata aaatagtcaa aatttttgcc gatatttcag tttaagagga gagattgaat
      241 tgaaattaag agcaaacata attgaaaaaa gaggaacatt acaagtagtt gtatcttata
      301 aagactctaa cggaaaaatt agacaaaagt ggaaagatac aaaattaaaa aagaaaggaa
      361 ataaaaaacg agcagaaaaa attagagatg aatttttact agaattggaa agtcaattag
      421 ctatggaatg tgaatgtgct aatccaaatt tattgtttta tgactatttg cttaattatt
      481 tggaagtatc aaaaaaacaa gtagcattta acacatatgt tgggtataag cattacgtcc
      541 ataatcgaat ttacaagttt ttttatccta aaaaaattaa actaaatagg ttaaagcctt
      601 atcatttaca agagttttat caatatatgt taaatgataa ctgtacagca aatacggtta
      661 ttcattatca cgcatttata cgcaaagctc ttcaagaggc tgttattaca gaattgataa
      721 gtacaaatgt agcagataaa gtaagaaagc caaaaaagaa acaatttgtt tctcaagttt
      781 ataatcaaca agagatcttg aaattacttg acattttgtc agaagaaaaa ctctatttgg
      841 tagttctttt aacagcattt tatggattgc gaagaagtga agttttagga ttaaaatggt
      901 ctgctattga ttttttaaac aaaaaaatca tgataaacca tgtaatcata gaaaatccag
      961 agaatatgtc acagttaata aagaaagatc aaacaaagaa ctcttccagc tatcgtacat
     1021 tacctttggt tgaaacgatt gaacgagcat tagtaaatca agctaaatgg caacaagata
     1081 atcgtattct tttaggagat gattatattt tagaagataa tgagtacgta tttactatgg
     1141 aagatggacg gttgatgaag cctcaatatg taacgcatcg tttgagtaag ttgattaaga
     1201 aaaatggatt gaaaaaaatt cgctttcatg acttgcgtca ttctaatgct tcaataatgt
     1261 tagatagtgg ccagaatatg aaatccattc aagaatggct gggacatgca tcgtattcga
     1321 caactgctaa tttatacacg catttaaccg caggagtaaa agatcgtgca gcagaagcat
     1381 tagaaaacgc atttgggttt aaagaataaa aaaacaaaaa acaatatctt tggggtatcg
     1441 cttcttgttt ttagaatttt tttgttggca atttgttggc agtatgttgg caatgaaaaa
     1501 attcacaaac taaaaaccta tttataaagc tttataaaac ttttttcaca aatagagcat
     1561 ttggttaaga gtcagctgct ctaccaactg agctaacggc ccgtacaaaa agtacttaat
     1621 aatagtagca ctaagaattt taaaatgcaa gactacattt aaagaaaatc agaaaaatct
     1681 ttacttcctt ataggaaatc attcatagat tattcacatt tgctcgctat tatataagca
     1741 taccaacaaa caaagttctt gcaagagaac aaaccctaac acttttttca ttttttactc
     1801 ctttcccgcc gtctccccgg cgggtctcct gttcttaacg ataaaagaca agaaggctta
     1861 gccttcttgt tttttgtttt catggaatcc cgctaatcaa atcacctagt taaagcaact
     1921 agattgaatg tttatcataa gtctgatatc atgtttatga aatgaaaaaa ggagcggtta
     1981 tgatggaaaa aatgcgtcag caattaatgg agtgggggaa ggaactagaa acattccgtc
     2041 tgcctcactg ggaagaactc cctgacttag aactttatat ggaccaagtc agaacgttag
     2101 ttgatcgtta tctttcacct gtgatacaag gagaaaagca tccattgctt acctcttcta
     2161 tggtaaacaa ttacgttaaa ctaggtttga taccagcacc agttaaaaaa agatataaca
     2221 aagaacacgt agcattttta cttgcaatca ctacgttgaa acaagtattg actattcctg
     2281 aaatcaaaga agggatattg ttccaaggaa aaacagtagg aattcgtgaa gcctataatc
     2341 tattttgcga tgaacaagaa gcagctgtgt ggatggtcag ccaattagca caaggtaaat
     2401 ctcatccgca aaaattcgac caggcaaccc ctgtagaata tattgctgta agagcggcaa
     2461 ctttatcgtt tgcaatgaaa cttcttgcgg aaaaaacgat tgttctagaa accgaatatt
     2521 taaaagagga gaaaacaaat gaaaaacaat aaaatcgcaa ttttagtaga ttcaggtacg
     2581 gatgttccag aagaattgat aaaaaaatac gagatgtata tgatcccatt gaaaattatt
     2641 tataaagatc aggtatatac agataaaatt gacattaccc ctgaagagat ctatcaacgt
     2701 ttgccagagg aaatccctgg tacatctttg ccggatggtg agtcgatcac agaaatcttt
     2761 gagcaaatca aaaaagacgg ttatgaaaag gtacttgcgg taacaatttc cagtggattg
     2821 agcgggacat ataatgtggt tcgtttaatt gcacaacagc aagaagaatt ggaagcatat
     2881 gtactagata cgaaaaatat tggtattggt gcaggttttt ctgcgatcca agcagcaaaa
     2941 tggctggaag aaggagtaga atgggatcaa ctgatcagta atctgaatga gttagtcgaa
     3001 agaacaaaag ttttctttaa tgttgcgaca ttggaatatc ttcaaaaagg tggacggatc
     3061 ggtttagttg cttctattgt aggaaccgct ttaaagctta acccaatcat ctcatgtaat
     3121 gaagaaggga tttattacac agtaggaaaa gctaggggac gtaaaaaaag tttggataaa
     3181 acggttgctt acgtcaaaga aaaaatcggt aatgcaaagg tcttcaactt agctgttgcc
     3241 catggggatg cgaaagaaga agcaattgaa atggaagcga gacttaaaag agagttccca
     3301 caagcaaacc aaatctactt tggccagatt tctccggcat tagtagtcca cactggtccg
     3361 ggattattgg gtgtcggtgt acaagtttta gaaggataaa tcaaaaaaag gaaacactga
     3421 ggtgaaaatc agtgttttcc ttttttattg aagttagaac aaaaaataat aaagtatttt
     3481 gcactttcat tttaattttc tcttttgttt tataggcaaa gatgaaacaa aagcagaaat
     3541 acggtataat gagaaggtat gacaataata tataagaggt ggctctttat gaaaaaagtt
     3601 ttagttgtcg atgatgagaa gccgatttcg gatatcgtca aattcaattt agccaaagaa
     3661 ggctatgacg tttatactgc atatgatggg gaagaagcct tggaaaaagt tgctgaggta
     3721 gaacctgatt tgattttact tgatttgatg ctacctaaaa tggacggctt agaagttgct
     3781 cgtgaggtac gcaaaactta tgatatgccg atcattatgg taacagccaa agattctgaa
     3841 attgataaag tcctaggctt agagttaggc gccgatgatt acgtgaccaa gccattttcc
     3901 aaccgagaat tagttgcacg tgtcaaagca aatcttcgtc gcggtgccac ggctgcgaag
     3961 gaaccagaag aggcagcacc tgcggaattg acgattggtg atttgacgat ccatccagaa
     4021 gcttacatgg tgacgaaacg aggagaaaca atcgagttaa cacatcgtga attcgaacta
     4081 ctcttttact tggcgaagca ccttggacaa gtgatgacaa gagaacattt attacaaacg
     4141 gtttggggtt atgattattt tggagatgta cgaacagtgg atgtaactgt acgtcgtttg
     4201 cgtgaaaaga tcgaagataa tccaagccat ccaaattatt tagtgacacg tcgtggtgtc
     4261 ggttactatt tgcgtaaccc agaacaggag taattggatg aaaagaaaag tccgcttttt
     4321 tcgatcagtc aattttaaga tcgctattac ctttattctg attttattga tctcgatcga
     4381 aattattggt gcctacttta tacgtggttt agaacgttcc acgatcaata catttattaa
     4441 agatatgaat caaacggtgg aatcattagc aacaacaatc agcccggaat tgaatcgaaa
     4501 agataatgca gatgatgaag aggtaaatgc gaatatcaaa agatttattg aaaacagtgc
     4561 gactagcgat atcatcgaaa tacgggtcgt tgacgaaaaa gggatcatcc gaggaacaac
     4621 cgatgtcaat gaacaaagcg ctgtgggaaa gaaaaatgat tatgttgata tcaatgattt
     4681 cacgactaaa cgttatgttg ctttagataa cgacgataaa cgggtgaata tcaatgttca
     4741 accgatcctg tccccgaccg gcgatgccgt tatcggggct ctttacgtca aaagtaatat
     4801 cgaacaaaaa tattcggaaa tcaataacac agcagtcatt ttctttactg cctcactaat
     4861 tgcggcattt atttcaatga tcgtatctgt tttagttgct cgttcgatta cacagccgat
     4921 cggtgaaatg agagaacaag ccattcgaat cgctagagga gactacagtc ggaaagtcaa
     4981 agtgcatgga caagatgaac ttggacagct ggctgatacc ttcaatcagt tagctgaacg
     5041 tattgaagaa gctcaagata caatggaagc tgaacgcaat cgtttggata gcgtgctatc
     5101 ccatatgaca gacggcgtca ttgcgacaga tcgcaggggt aaagtcatta cgatcaatga
     5161 tatggctgtt tccttgctag atatcaaaaa cgaggaagca atcggacaat cgattttgac
     5221 acttttagat atcgaagaag aatatacgtt gcggaaatta ttagaagatc caaacgaaat
     5281 ggtacttgac cgttcaacca gtacattgga aagtgatcag atgatcttgc gagtagactt
     5341 ttctatgatc cgtcgcgaat caggttttat cagcggatta gtagctgtct tgcatgatgt
     5401 gacagaacaa gaaaaaacag aacgggaacg tcgtgaattc gtctctaatg tttcccatga
     5461 acttcgtaca ccgttgacaa gtatgcgtag ttatatcgaa gcattgagcg aaggtgcgtg
     5521 gaaagacgag gaagtagcac caaatttttt gaaggtaacg ctagatgaaa cagaccgaat
     5581 gattcgaatg atcaatgacc tcttaaatct atctcgcatg gatacaggta atacccagct
     5641 tcaattagaa tatgtcaatt tcaacgagtt agtgaatttt gttcttgacc ggtttgatat
     5701 gatggtggga aatcaggaaa aaaattataa gatccgtcgt gaatttacgc aaagagatct
     5761 ttgggtcgaa gtagatacag ataaaatcat ccaagtagtc gataatatca tgaataacgc
     5821 gatcaagtat tcaccagatg ggggaacgat tacttgtcgc ttattagaaa cgcataataa
     5881 cgtgatttta agtatcaccg atcaaggatt ggggattcct aaaaaagatc tgaaccgagt
     5941 gttcgagcgg ttctatcgag tagataaagc acgtgcaaga gcacaaggtg ggacaggact
     6001 tggattagct atttctagag aagtgattaa ggcgcatcga ggcgctattt gggcagagag
     6061 caaggaagga aaagggtcga ctttttatat ctcgctgcca tatgaacctt atgaggagga
     6121 atggtgggaa tgagaatctc tgaaaaagtc gttcgtatag gactcatttt gatggttgcg
     6181 ttaagcatat acttctctta tgcaatctgg ctgagcccag caggaaaaag ttcaatcaac
     6241 gtagatgaga caaacactca aatgatcgag tctcaaagca atcgaaaaac ttccgaagtc
     6301 tttcttccgc ttcatgttac atggcaccat tcgggaatga tccaagaaac caacagtgaa
     6361 aatctcgtgt accgattgca attgatcatc gataaagcaa gatttggaaa gctttctgaa
     6421 gtagtttcag gagacaaatc acagtttgaa caggtgaaaa atctgaactc tggttttgag
     6481 ttggcctata atgcgccttt tttgctaaga gaatacaagg aagcatttga tttagattta
     6541 gatgtgtcga acttggcaaa agaaagcgaa aatatgtatt ttactagaat acaattcgat
     6601 caaggaaata aaaaaatccg atttttgaat tattcgaacc atctcgtata tgaagcaaat
     6661 atttcgttga attggacaga tatcaataaa gaattaacag caaaagacac aaaatggaca
     6721 gaaatgacaa cagaaccatc gacgatcgac acgcaatatg ctacgaaaca ttcgatcaaa
     6781 ctgaagaagt atagttatat cctgtcacag caaccctata cactttttag aaatgctttt
     6841 ttccagaaac cagatagcgt gaaaaataat gatgaaagca atgaattgat tttttacggt
     6901 gggaatgaaa caatgtctat ccattcggaa acgcaagtag ttgattttcg tggagagctg
     6961 ccagagaaaa aagaaaatgc tagtgtattt tctgaaagtt tcccctatat tagcaaatta
     7021 ggcagttctt tagggaacct cagatatttt gaccgcagtg acaatacgat cgattatcgg
     7081 atattcgtgg aaggcttccc ggtttttggg acagacagca gaggacagat tggtgtggaa
     7141 gttggcggtg aaacgaatgg ttctgtgcaa gtgaatatcc aaaccagttt gaatacgatt
     7201 caagtgccga taccttcaga cgaagaagta gaacttgcaa gtacgaatga aatcatccag
     7261 cagttaaaag ctaagggagc agatagcaac aagattggtt cagtgatcgt tggctataca
     7321 tggcaaaatg tcaaagaaac gaatcgtgtc gttgatctct tacctgaatg gtatgtgaaa
     7381 tataaagata actggtattc agctaacgac cttctggaaa aattacctgg attggaggcg
     7441 aattaattgg atttcaaaaa aatcgaatgg atatttttcg tcgctttttt agggttgaat
     7501 gtgtttttat tcagcagtta tcatgacgcg gtataccaag aaaacaatgt cattcgctct
     7561 aatcagactg aatcaatcca acaacgtctg gctagcgacg atatcactta cacggggaag
     7621 atttcgtctg agaacaagca aggctattat cttagcgcgg agcagaccaa tcttagcact
     7681 tcattagcga attatcgcaa ggctggtaaa agcggcttgc tggcaagtgg tgtgttttta
     7741 gacggtgatg ttttgacgaa atctttatcc agttcagatg ctgaaaagaa cgtgatcgat
     7801 ccagataaaa ttagtagttc cttggaagat tttttatcta acaaagacaa tattttattc
     7861 ggtaatgatt atgtgtacac gaaaaacttt tctcatttag aagaagaacc actagaaatc
     7921 caagcaagcc aagagtatga aggcatccca ttcaatgatg atacagcaaa aatcgttctt
     7981 tctttagaaa aaaacgataa tgattatagc atcacgaaat acatgcagac gcatttatct
     8041 gatatcgagc agctgcgcga aaagacggaa ctgtatacgg aagaggaagc aatcaataca
     8101 ttgtacatca ataacaaaat accaagagga tcaaaaattt tatggcgtca gctagcttat
     8161 tcctgtattc tgaaagtccg ggaaaaaaat gtgtatgttc ctgtttggca tgtagcgatc
     8221 gaaacaagcg ataaagtggt ccaaattgag agcgtcaacg ctttcagcaa tacgatcgtg
     8281 acaaacaata ctgtaccaaa agtggaagat caataaaaaa gcgagtataa tgaaaaaagt
     8341 ttacaaagta agaagggaag taggagtcaa atggctgaag aaaaaccagc ttttaaaatc
     8401 agtatcctag caagtggaag ttcgggtaat tcactttata tcgaaagtga aaaaaaacgg
     8461 cttttggtcg atgcaggact tagcggtaaa aaaatcactt ccttgatggc tcaaattgat
     8521 cggacaccgg accaattaga tggaatactt gtgacgcatg aacatcgaga tcatatacat
     8581 ggcgtgggtg tcttggctcg taagtatcat ttggatgttt ttgccaatca gcagacttgg
     8641 gaagcgatgg aaccactgat tggaaatgta ccagtggaac aaaaacatct atttgagatg
     8701 gggaaagtca gaacattcgg cgatatcgat attgagagtt tcggcgtctc ccatgacgca
     8761 gcggctccgc aattttatcg tttccataaa gaaaatcggt cattcgtcat gttgacggac
     8821 accggatatt gcagtgatta tatgcgaggt gtcattgaaa atgccgatgg ttatttgatg
     8881 gaaagtaatc atgatcttga gatgttacgc atgggacctt atccgtggaa tttaaaacag
     8941 cgtattttag gagatagagg acatctttcc aacgaagacg gtgcacttgt catgactgat
     9001 gtgatcggta atcggaccaa acgaatctat cttggccatc ttagcaagga aaacaatatg
     9061 aaagaacttg ctcatttaac aatggaaaat gttttgaaag aaaaagattt tggcgttgga
     9121 catgattttg aaatctatga tacagatcca gatgaagcaa ctgagctatt ttcgatttaa
     9181 acagttcaat caataaaaat ataaaaagca gaagataaaa tcaatcaggg ttggttttat
     9241 cttctatttt tattttttta gcatattaaa aaaataaccg tattatcgac tgactacact
     9301 gatgtgctgc ttttcatgtt tctcatccag tatctcatct actaatgcaa tcgcgtaatc
     9361 tgccatgctg atcgtactgt cgctagcagc gtttctttgt aaataatcat cacttaacaa
     9421 ataagtacct gtacgtttgc catgtggatc aaataaagaa gctggactga tataagtcca
     9481 atgtagattt ttagattgtt tcaattttaa caatccttcg tacatattga aagctgttgg
     9541 atagaagggt gcatttttag gtacttggtc aatcatacga gtcgtctttt ctgtatctaa
     9601 gaataacgaa gaggcacccc caacgacaat taagcgtgta tcggttcctt caagcatctc
     9661 aatcaaatgg gacaaagaag tttgatgcat ttcttctttt cctttgggag cgttgaaagc
     9721 atcaacgaca acatcaaaag atgcaagatc agtagttgtc aactcaaata aatccttttg
     9781 tataaacgga acatctgatg gcaatttttc tggatgacgc acgattgccg tcacgtctaa
     9841 atctctggac aatgcttcgt ctaaaataaa tgaacctgca tggccagtag ctccaatgag
     9901 tgcaattttc ataaaaaacc tcctttttta ttcctgtcca ttgtaagcag ttgctgaata
     9961 ttcgtcaaag aatccgattt ttgaaaagct cagtgcgcat tcctttcatg gttcgtgatc
    10021 attgggtata gttaaattaa gaaaactgat tgataaaaat agaagttgaa ggagataaga
    10081 aatgaaagag tggttagatc gtgccttttt accaatgata acatctgttg tgaatcttag
    10141 acccttaact gctttgcgta atggaatgac ttacacgatc ccaataatta ttgttggctc
    10201 gctgtttttc ttatttgctc attttcctgt ggattacatc gctcagtgga tagacaaaac
    10261 aggattttct atgtatttta cacaagtata ccaggctaca tttgatgtga tagccttttg
    10321 gatcgttttt gccattgcat acgcttatgc aaaagaagaa gacatcgatc gcttaccagt
    10381 cggcataaca gccttgtctg cttatctact gcttattcag ccactaaata ctcagataga
    10441 tactgtctgg acaggtgctg aagggatact aggagcagtt acaactgggc tcatcatcgg
    10501 atggggctat gcacgtttag taagacttgc gaaagggtgg aagcaaagag agaagatacc
    10561 tgaaaatgtt tggcagtctt ttacttcatt gattccaatc attgttatag tcacttttac
    10621 gcttatcggt tcagcggttt ttcaacattt gttcagaatg actgttgttc aaggagtatg
    10681 gacatatgtc cagcttccca ttcaatcgtt catagacacg ttgtttggtg tgcttttatt
    10741 aggttttttt gttccgtttt tatggttatt tggtcttcat ggatctgcga tggtcaatgg
    10801 gttggttagt cccgtcttgc aagcgaattc attagcaaat gcagaaatct tagcctcagg
    10861 acaagagttg acggtggcaa atggcggaca tatcgttact cagcaatttc tcgatcagtt
    10921 catgacggtt acgggtgctg gattgacgtt aggggctgta ttttttatga cggtttttgc
    10981 gaaatcgaag aaatacagag aattaggaaa tcttgctctt ttaccagcct ttttcaacat
    11041 caatgaatca attatttttt ccacaccgat cgtgatgaac ccgatgatgg ctgttccttt
    11101 tattttcgca ccggtcgttt caggattgat tacctattcc gctttatatt ttggattcgt
    11161 tcctttattt acagcagtcc aagtcccttg gacaacaccg ccgatcctct cgggtttctt
    11221 agtaggcgga gtgcctgcag cgattttaca aggtatcgtg ttgtcaatta gttttttcat
    11281 ttatttccca tttttgaaaa aaatagattc tgcaaactgc aaaaaggaaa gacagacaaa
    11341 aaatgatgga gcagcagaaa agatgaacga ctaaaaaaca aaaatactcc tgtcgcttta
    11401 gattgggaaa atcaccaatc taggatgaca ggagtattta tagtcatgtt tatactagcc
    11461 ctttttggac agctaattga acaagaacaa ctaatgtgtt cattcctacg tgtgtgatca
    11521 tcgatgtcca gatccgacca gttgctttgt actctaggct gaagaagaaa cctaggaaaa
    11581 agtagattag cagatgacca tcattatgag caaacgcaaa cagcaaagag ctgatcactg
    11641 ctccgaccca aaaatttgaa tatcgactga tgatccccag tatactgcgg cggaatacga
    11701 actcttccat gatgggtcca gcaacagttg tcgccaaaat aaaagcgggt gcttccatga
    11761 tcatctggat gatattttgt gtattctcgg aaggggttgc tttgccaaac aatacagatt
    11821 ctaacatgac agcgatgctt tgcagaatca atgcgacaaa gattccaacc aatccataaa
    11881 taacaatctt tggagcagaa gcttttttta ccgctgattc gatcgctaag ggttcacgtt
    11941 gcttaaaata aaaaatagct aggacaacgg cgcctagtat atacatgact gcagttgctg
    12001 tgatcaattc agacgtagat tttacaagtc ctatcgaagc taggatcaag ggtgagataa
    12061 aaattagacc atagcaaaaa atgctgagga agctatattt ttttaaagac atgtaattcc
    12121 tccttttaag ggataacaag catgcaaggc aagcttatat cgattgattt caattatatc
    12181 ataatttcaa taagcagctg tcagaataaa atttcttttc tttgatttaa aagcttgcaa
    12241 aaaagaggga gaatgagtat tattaaaaat gtaggttagc actcgaaggt taagagtgct
    12301 aacagattaa aaaaagagtt atcggaggga tttatcgtgt taaaaccatt aggtgatcgc
    12361 gtcattatcg aagtcgcaaa agaagaagaa aaaactgtcg gaggaatcgt tttagcttct
    12421 gctgctaaag agaaacccca aactgggaca gttgttgcag tcggtgaagg ccgtttgtta
    12481 gaaaacggtg aaaaagttcc tgccgctgta aaagcaggcg accaagttat gttcgaaaaa
    12541 tacgccggta cagaagtaaa atacgaagga aaagaatatc tgatcgtcgc aggaaaagat
    12601 atcatggcga ttgttgagta aatttggaag ataaaaaaat aatcaaaaat aatcaatgag
    12661 gtgaatcaat catggcaaaa gaattgaaat ttgcagaaga cgcacgcgca gctatgttac
    12721 gcggggtaga taaattagca gatacagtga aagtaacatt aggacctaaa ggccgaaatg
    12781 tcgtactaga aaaatcttac ggctctccat tgatcacaaa tgatggtgtg acgatcgcaa
    12841 aagaaatcga attagaagat cattttgaaa acatgggtgc aaaacttgta tcagaagtag
    12901 catcaaaaac aaatgatatt gcaggagacg gtacaacgac agcaactgtt ctgacacaag
    12961 caatcgttcg cgaaggttta aaaaacgtaa ctgcaggtgc taatcctcta ggcattcgtc
    13021 gcgggatcga attggcaaca aaagcagcag tcgaagaatt gcataatatc tcaactgttg
    13081 ttgattcaaa agaagccatt gcacaagtag cagctgtttc ttcgggttct gataaagttg
    13141 gacatttgat tgctgatgca atggaaaaag ttggaaacga cggtgtcatc acaatcgaag
    13201 aatcaaaagg gatcgaaaca gaactagatg ttgtagaagg tatgcagttt gatcgtggtt
    13261 acttatcaca atatatggta acagataacg acaaaatgga agctgttcta gaaaacccat
    13321 atatcttgat cacagacaaa aaaatctcta acatccaaga tattctgcca ttgttagaac
    13381 aaatcttgca acaatcacgt ccattgttga ttattgctga cgatgtagat ggtgaagcat
    13441 tgccaactct tgtattgaac aaaatccgtg gaacattcaa cgtagtagct gtaaaagctc
    13501 ctggtttcgg cgatcgtcgt aaagcaatgc ttgaagatat cgctattttg acaggtggta
    13561 cagtaattac tgacgatcta ggtttagaat tgaaagatgc aacaatcgaa aacttaggaa
    13621 atgcttctaa agttgttgta gataaagaca atacaacgat cgtagaaggt tctggagaaa
    13681 aagaagcaat cgaagctcgt gtgcaattga tcaaaaacca aattgctgaa acaacttctg
    13741 attttgaccg cgaaaaatta caagaacgct tagctaaatt agcaggtggt gtagctgttg
    13801 ttaaagttgg tgcagctact gaaacagaat tgaaagaatt aaaattacgc attgaagatg
    13861 cattgaatgc tacacgtgcc gcagtagaag aaggaatggt ctcaggtggt ggtacagctc
    13921 tagtgaacgt tatcagcaaa gtttctgctg tagaagcaga aggagacgtg gcaacaggta
    13981 tcaagatcgt tgttcgtgct ttagaagaac caattcgtca aatcgctgaa aacgctggtt
    14041 atgaaggatc agtgattgtt gataaattga agaacgtgga actaggcact ggtttcaatg
    14101 ctgctactgg agaatgggta aacatggttg aagcaggtat cgtagaccca actaaagtaa
    14161 cacgttctgc cttgcaaaat gccgcttccg tttctgcctt gttattaacg acagaagcag
    14221 tcgttgcaga taaaccagaa ccagcagcgc cagcagctcc tgcaatggat ccatcaatga
    14281 tgggcggtat gatgtaagaa aaagcaactt gcttatctac aactgatcat tagtgaaaga
    14341 cagataaaaa gaggctggaa cagaagcgtt taactccaag aaataagaag aaattcacgg
    14401 aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc
    14461 cgctgtttat acgtgtttag agcgtgagac aaaagt
//
LOCUS       DAFTHM010000066        14376 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFTHM010000066 DAFTHM010000000
VERSION     DAFTHM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.066"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            142..523
                     /locus_tag="L7C88_001925"
                     /pseudo
     CDS             142..523
                     /locus_tag="L7C88_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303242.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            654..1604
                     /locus_tag="L7C88_001926"
     CDS             654..1604
                     /locus_tag="L7C88_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002821555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBP9558739.1"
                     /translation="MLKTYSLTKDTLLVSSESNIKNSSVVYVYGDEREYIESSEHKYD
                     FKIGNILTFDDRVAYDTMIDKNDEKSLLVSFLFPEVHEGGHLDTLTTSVVFLVFKNKL
                     IIFTKQKLKFIPELLSNMVLRDVNHFVEEVLLKIMQKDFYMMLNDLRGVKEKIDDLDS
                     EISTSGSLKPTFGDLLTLQKYMIALSTTYKANHKALDFIKKNFTTIDDIDFSTKKIID
                     DLYDTSDTMDRIILSYSQYLDKLENMINNMISYQLNMIMKTLTEISIVLTIPAIIFGF
                     WGINVHVPFEKSSYGVLAVLIISAILSLICWLLMRRKTYL"
     gene            2122..2577
                     /locus_tag="L7C88_001927"
     CDS             2122..2577
                     /locus_tag="L7C88_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBP9558740.1"
                     /translation="MVQQIVLPIKDSSVLKMVQDTLLDSFRAGRRNYTVFQVGKATLL
                     RVSDVMTLKKSDVYNPDGSVKNATFIHDKKTGKANTLYLKPVQQDLLQYHDWLAQENI
                     NSEWLFPSTAHYDLHITEKQFHKVMAHVGDLLGINLEDKEKKLRVRKPF"
     gene            2918..3520
                     /locus_tag="L7C88_001928"
     CDS             2918..3520
                     /locus_tag="L7C88_001928"
                     /inference="COORDINATES: protein motif:HMM:NF013878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558741.1"
                     /translation="MLDPLFTDETFITFGFGHLVELAEPGHYDEKWQNWKLESLPIFP
                     DRYDFEVAKDKGKQFKIVAELLKKANTIIVATDSDREGENIAWSIIHNANAFSKDKTF
                     KRLWINSLEKDVIRSGFQNLQPGMNYYPFYQEAQTRQIADWLIGMNASPLYTLNLQQK
                     GVQGTFSLGRVQTPTLYLIFQRQEAIENFKKEPFFEVEAK"
     gene            3614..3946
                     /locus_tag="L7C88_001929"
     CDS             3614..3946
                     /locus_tag="L7C88_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase I"
                     /protein_id="HBP9558742.1"
                     /translation="MGNQEGIIADVQTKEKKTNSPSSFSLSSLQSKVNQLYKATASQT
                     LKAMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMLLSLIMIRSN
                     NSTQILTN"
     gene            complement(4097..5076)
                     /locus_tag="L7C88_001930"
                     /pseudo
     CDS             complement(4097..5076)
                     /locus_tag="L7C88_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332307.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(5081..5848)
                     /locus_tag="L7C88_001931"
     CDS             complement(5081..5848)
                     /locus_tag="L7C88_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBP9558743.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            6338..6763
                     /gene="lacA"
                     /locus_tag="L7C88_001932"
     CDS             6338..6763
                     /gene="lacA"
                     /locus_tag="L7C88_001932"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HBP9558744.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            6780..7295
                     /gene="lacB"
                     /locus_tag="L7C88_001933"
     CDS             6780..7295
                     /gene="lacB"
                     /locus_tag="L7C88_001933"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HBP9558745.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            7306..8238
                     /gene="lacC"
                     /locus_tag="L7C88_001934"
     CDS             7306..8238
                     /gene="lacC"
                     /locus_tag="L7C88_001934"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HBP9558746.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            8241..9221
                     /gene="lacD"
                     /locus_tag="L7C88_001935"
     CDS             8241..9221
                     /gene="lacD"
                     /locus_tag="L7C88_001935"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBP9558747.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            9249..9566
                     /locus_tag="L7C88_001936"
     CDS             9249..9566
                     /locus_tag="L7C88_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBP9558748.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            9566..11272
                     /locus_tag="L7C88_001937"
     CDS             9566..11272
                     /locus_tag="L7C88_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBP9558749.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            11414..12820
                     /gene="lacG"
                     /locus_tag="L7C88_001938"
     CDS             11414..12820
                     /gene="lacG"
                     /locus_tag="L7C88_001938"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBP9558750.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            12843..13115
                     /locus_tag="L7C88_001939"
     CDS             12843..13115
                     /locus_tag="L7C88_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HBP9558751.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            13136..14035
                     /locus_tag="L7C88_001940"
     CDS             13136..14035
                     /locus_tag="L7C88_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBP9558752.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         4695 a         2371 c         2771 g         4539 t
ORIGIN      
        1 gcgtttgatt ttcaaacttc gcaacagaac cgatgacact atcgttcttc atcaacgtaa
       61 gttagatttg ttgaaagagc agaaaaaagg atttctacaa aaaatgtttg tttgatattt
      121 taaatagaaa agagagataa agtgaagttt ttaaattttt tgaactataa atatttaaac
      181 tgggtattat atggtattac attatttttt attatttatt acttttttac cgatgatgat
      241 atttttttaa ttttagcaat actttttctt gtttcatcta attttagtga taacttaatt
      301 gaagttctta cagaaccaga aattcggtct atgacggatg aagaacaaca gattattaaa
      361 gctatgattt cggaaaataa gaaagacgta gtagttatca aaaagattag agagtataca
      421 aatttaggtg ttttacaagc caaaaaagta tatgaaaaaa aaaaaaaggg tctataatta
      481 caaattagat aatacattag aagctggaga caagattgtc tagataatgt gtgagataaa
      541 atttttggca ggttatcata cataagacaa aatgttttta aaactgataa cgtatttatt
      601 ccacaacaat tacgcattta tttctgagaa aaatataaag caggaggatt acaatgctga
      661 aaacttattc cttaacaaaa gatacattat tagtttcgtc agaatcaaat atcaaaaatt
      721 cttctgttgt ttatgtttat ggtgacgaac gagaatatat cgaatcttct gaacataaat
      781 atgactttaa aataggcaat atactaacgt ttgatgatcg agttgcatat gacacgatga
      841 tagataagaa cgatgaaaaa agtttgctcg taagtttttt gtttcccgag gtacatgaag
      901 gtgggcatct agataccctg acgacatctg ttgttttctt ggtatttaaa aataagttga
      961 taatttttac aaaacaaaaa ttaaaattca ttcccgaact cttatccaat atggttttac
     1021 gtgatgtcaa tcatttcgtg gaggaagtac ttttaaagat catgcaaaaa gatttctata
     1081 tgatgcttaa cgaccttcgt ggagtcaagg aaaaaattga tgatttagac tcagaaatat
     1141 caacgtccgg ttcactcaaa ccaacgtttg gtgatttatt gactcttcaa aaatacatga
     1201 tagctttgtc aacaacttat aaagctaacc ataaagcgct tgatttcatt aaaaaaaatt
     1261 tcacaactat tgacgatatt gattttagta ctaaaaaaat aattgatgat ttatacgata
     1321 caagtgatac aatggataga atcattttaa gttacagcca atatttggac aaattggaaa
     1381 atatgataaa caatatgatt tcgtatcagc taaacatgat tatgaaaacc ctaaccgaga
     1441 tatcaattgt tttgactatt ccagcaatta tttttggctt ttggggaatc aatgtccatg
     1501 tcccgtttga aaagtcttct tatggtgttt tagccgtatt gattatctct gctatactaa
     1561 gtctaatttg ctggcttttg atgcgacgca aaacatattt gtaaagtatt tgtgataccc
     1621 taatatgatt taaagcagaa tttctttgtt gactttttaa aaggctgatt cctttcaata
     1681 atttaatagc ttcagcggct gctcagaagt caataaattg gactattttt attcagttac
     1741 ttaggcaaca tttgagatac gattgcgatt ataaaaattg atataccaac caatggctgc
     1801 ttggaagact gacatattag cctcgatatc atcgaataac taaatacaga aaaatacaat
     1861 aaatattatc aaactaggga ctatactaga aaacatcagt acattcctta actcagggtc
     1921 tataattaga aaatcgcccc tttgaaaact gattaaaaca gcccccatta tctagtgact
     1981 agataatggg ggctgttttt ttgttaagtg atataataaa ccataaaaga agtttagaaa
     2041 tacggtcctg gtcatcaata aataaacaat ttaattaatt atttatttaa ttatttaatt
     2101 tcagaaaggt atacatgaat catggtgcaa caaattgtcc tacccatcaa agactccagc
     2161 gtcttaaaga tggtacaaga tacacttctc gatagtttcc gtgctggtcg ccgaaattac
     2221 accgtttttc aagttggtaa ggccacgcta ctacgtgtga gtgatgtcat gacattaaaa
     2281 aaatcagatg tctataatcc agacggctct gtcaaaaatg caacctttat tcatgataaa
     2341 aagaccggta aagcaaacac gttatattta aagcctgttc agcaagactt gttgcaatat
     2401 catgattggc tggcccaaga aaatatcaat tctgagtggt tatttccctc gacagcccat
     2461 tatgatcttc atatcactga gaagcagttt cataaggtga tggcgcatgt tggtgatctc
     2521 ttaggaatca acttggaaga caaagagaaa aaattgcgag tcagaaaacc gttttgagat
     2581 atgaacagca tttgccttca cgccttagcg attttaaata atagccttga aagtgattat
     2641 ggaaaagccc tctacgctca atgcaaaatt gacgtagaaa ctatttttga tcgattgaaa
     2701 ggtgtatttg gtatgtgaag aacccatgtc agaggcaaga acgttgcacc tactgacatt
     2761 ggaatgatgc ttatgagcat gaatctaacc aaattatccc ttgaggctag aagaaaagcg
     2821 gaagcttttc aacacaaagc agccaaaaat aaaaaacgcg acgaagcaat cacatttatg
     2881 attattcatc gcgtttttta tatttagagc tagttatttg ctagacccac tatttacaga
     2941 tgaaacgttt atcacctttg gttttgggca tttagtggaa ttagcagaac caggtcatta
     3001 tgacgaaaag tggcaaaatt ggaaacttga atctttgccg atttttcctg atcgatacga
     3061 ttttgaagtt gcaaaagata agggaaagca gtttaaaatt gttgcagaac ttctcaaaaa
     3121 ggcaaataca attattgttg caacagatag cgacagagaa ggtgaaaata tcgcctggtc
     3181 gattatccat aatgcaaatg ccttttcaaa agataaaaca tttaaaagac tatggatcaa
     3241 tagcttagaa aaagatgtga tccgaagcgg ttttcaaaat ttgcaaccag gaatgaatta
     3301 ctatcccttt tatcaagaag cgcaaacacg ccaaattgcc gattggttga tcggcatgaa
     3361 cgcaagccct ttgtatacgt taaatttaca acagaagggc gtacaaggta cattttcact
     3421 aggacgtgtt caaacgccca ccttatacct tatttttcag cgccaggaag ccatagagaa
     3481 ttttaaaaaa gaaccttttt tcgaggtgga agctaagtaa aacaagggtc atttaagggc
     3541 gttctaagcc ccacacagcg ttttaaaacc caagaggagc tttttagctt ttgtttcttc
     3601 taaacaagct aaaataggca atcaagaggg gataattgct gatgttcaaa ccaaagagaa
     3661 gaaaacgaat agtccgagtt cgttttcttt aagtagtttg caatcaaaag tcaatcagct
     3721 ttataaagcg acagcgagcc aaactttaaa agctatgcaa ggactgtatg aagcaaaatt
     3781 attgagttat ccaagaacag atacaccatt tattacagag aacgaatttg cttatttaaa
     3841 agcgaatttt ggcaaatata gcggtttttt aggacttgat cttgaaatgt tgttatcatt
     3901 gataatgata cgttcaaaca acagcaccca aattttgacg aattagtgaa actctatgaa
     3961 aaagacgtag taaaacatgc aacatcctat tctaatcagc tggtaaagct taattaggtt
     4021 atataagctt gaaaataaag ggtttgtcca atatggacaa gcctttttct tatgttttgc
     4081 cacagatttg ccacacttat tgtgtaagag tatcaaggat aggtataatt tgatactttg
     4141 tttttttagt gatgtgcaaa taaatttctg ttacacgact acctctagaa tgccctacac
     4201 ggtcttgaat tgcttctagg ggtattcctt actctgctaa gaaactaata tgcgtatgac
     4261 ggaatatatg ggtcgtaata tgtttattaa aactaagttt attatcaata tcaattcctg
     4321 ctcgttttgg attacctttt cgatttaatt ttccattttc aggtgagttg aggaaattgt
     4381 taaggacact ataatgaaga ggtgttccat tatagtcggg tttatgacga cttttggaag
     4441 taaaaatcca tccattatct ttataatcag gattgaatct catatgttgg tgatttaact
     4501 caatttcctc tttaagaatt tctatagccc ttttagataa ttggacattt cggtaacttt
     4561 gtaagttttt tacattacct tcatagctat tttctgcagc tcctccgtga gtggactgac
     4621 taatgatgat attttgcttt tcaaaatatt gataggcacc aatattttgg agtttcgact
     4681 ctgtaagtca acagggccat tagttagaat acctattggg atgcggtttt tatgtagagc
     4741 cagcagtagt tgatgtatct caggaatcat cgtaatctga tcgagttcat attcatagtc
     4801 agcttggaag tctagagctt ctgtcctaga aatactatcg atgccaaatt cttccatagt
     4861 cttctgacag cgaaaaattc taagctgctc aatactgatg agttttttcg tgtatttagg
     4921 aaaagcaaca tcagaccaat atctgaaacg tttgtaaatg ttatctattt gttggatatc
     4981 aatcgttgga aaacatttct caacgctacg tttaaagggg agttgatggt cataaagagt
     5041 gtcatcaagg tcaaaaacaa tatttttata agtcataatt ctagtccgct tttaaaatag
     5101 tagtgtactg gctaaattcc tctaagtgtt gagggctaat ctggttatct gtaatgatgg
     5161 tatcgagttg atctagatta tagaagttaa agaaatcgta tcgatcgaat ttagtactgt
     5221 ctactaataa gaatttttct acagcattgt ttagggcaag ttgttgaatc acaccttcct
     5281 tgtcactata tgtagcaata gaattatggg taacagcatt tgcactaaca aaagctttgg
     5341 caaatctaat tgcttttaaa tttgtcgaag ccattgaacc tacaaaagct ccagttattt
     5401 ctctatattc accgccaaga agcaataaat caatggtttc gctatcattt agaatcaaga
     5461 acacagggag actatttgta atgacacgaa ttttataacc tttacgacct ttcaattcta
     5521 atgccagttg ttcaagtgta gttccaggtc caataaaaat agtatcgcca tctttgatta
     5581 aagagcaggc ttttttagca atgtcaattt tttcttttgt atttagactt ttcttctcga
     5641 tatgtgtctt ttcaagtggc tttttagagg aaagcaattg tgcaccacca tgagtacgtg
     5701 ttaaaagtcc atcagcttct agagcatcaa ggtctctacg ggctgtcata tcggaaatat
     5761 ctagttcatc tattatttct tttatggtta tggtcccatc aatctttaac atatctaaaa
     5821 ttttttctaa tcgtcgtttt ttgttcatat gaagaccctt ctttcataaa gtaatttttt
     5881 tccaaagata attctctttt aattgtatca taaaagacaa tattttcaag gtaaaacaaa
     5941 caatttcaaa caaaaacaaa tgttagatga tgaaataaga acagaggatt gacgtatatt
     6001 agcttaggtc agattttgta taagacgaaa ataaagtagg acctcttaat cagtaagtta
     6061 tagaaagtaa aagacttttg taatacttga atagatattt cacgtccatt ttgtgatgga
     6121 ttaaatgaac aaaaatgaac aataatttaa cggtgttatc tattttttaa aaaaacaaat
     6181 aaaaaaaaca aaaaataaac aaaaaaagtg ttgctttttg tttgaatgct tgatattata
     6241 taaacaaaga aatgatgaaa acgttttttc gaacattttg caaaatgttt tctacttcta
     6301 cgtagcattt ctttctaaaa tttaggaggt ggtcaaaatg gctattgttg ttggtgcaga
     6361 tctcaaaggt acgagattaa aagatgttgt gaaaaatttt cttgtagaag aaggttttga
     6421 ggtaattgat gtgactaagg acggacaaga ttttgttgat gttaccttgg cagttgcctc
     6481 tgaagtaaat aaagatgagc aaaacttagg tattgtaatt gatgcttatg gagctggtcc
     6541 attcatggta gcaactaaaa ttaaaggtat ggttgcagca gaagtttcag atgaacgctc
     6601 agcttatatg acacgtggac ataacaattc acgaatgatt acggttggcg ctgaaatcgt
     6661 cggtgatgag cttgctaaaa acatcgctaa aggtttcgtc aatggtaaat atgatggcgg
     6721 acgtcatcaa atccgagtag atatgcttaa caaaatgtgt taagaaaagg agttaaggaa
     6781 tgagaatcgc aattggatgt gaccacattg tcacagatga aaaaatggca gtatcagaat
     6841 tcttgaaatc aaaaggacat gaggtccttg atttcgggac atatgaccac gcacgtactc
     6901 actaccctat ctatggtaaa aaagtcggtg aagcagtagt aagtggtcaa gcagacttgg
     6961 gagtatgtat ctgtggtaca ggtgtcggca ttaacaatgc agtcaataaa gttccaggtg
     7021 ttcgctcagc gttggttcgt gatatgacat cagctatata tgcaaaagaa gagttaaatg
     7081 cgaatgttat cggtttcggt ggaaagatta ctggtggtct tcttatgaat gacatcattg
     7141 aagctttcat tgaagctgag tacaaaccaa cagaagaaaa taaaaaattg attgcaaaaa
     7201 tcgaacacgt tgaaacacat aatgcacatc aagcagatga agatttcttt acagaattcc
     7261 ttgaaagatg ggaccgtggt gactaccacg attaaggtat aacaaatgat tctgacagtc
     7321 acactaaatc cttcagtaga catctcttat cctctagaaa cattgaaaat tgatacagtg
     7381 aatagggtga aagatgttag taagacagct ggtggaaaag gcttaaatgt tactagagtc
     7441 ttgtatgaat ctggtgataa agttactgct acaggtttct taggtggtaa aattggtgaa
     7501 tttattgaaa gcgaattaga acaatctcct gttagtccag ctttttataa aatctcagga
     7561 aacactagaa actgtattgc tatcttacac gagggtaacc aaacagaaat tttggaacaa
     7621 ggaccaacaa tttctcatga agaagcagaa ggctttcttg accactatag caatcttatt
     7681 aaacaatcag aagttgtgac aatttcagga agtttacctt caggacttcc caacgattat
     7741 tatgaaaaac ttatccaact tgcttcggat gaaggagtag cagtcgtttt ggattgttca
     7801 ggtgcacctc ttgaaacagt tctaaaatcg tcggctaaac ctactgccat caaacctaat
     7861 aatgaggaac tttcacagtt gcttggaaaa gaagtaacaa aagatattga agaactcaaa
     7921 gacgttctta aagagtcact ttttagtggt atcgaatgga tagtggtctc attaggtcga
     7981 aacggtgcct ttgcaaaaca tggtgatgtt ttctataagg tagatattcc tgatatccca
     8041 gttgttaatc cagtcggatc aggggactca acggtagctg gtattgcatc agctttaaat
     8101 agtaaaaaaa gtgacgctga cttattaaaa catgcgatga cattgggtat gttaaatgct
     8161 caagaaacaa tgacagggca tgtgaatatg actaattacg aaacactaaa ctcacaaatt
     8221 ggagtaaaag aggtataaaa atggtactta cagaacagaa acgcaaatct ttggaaaaaa
     8281 tttcagataa aaacggtgtt atctcagctt tggcatttga ccaacgtggt gctttgaaac
     8341 gtttgatggc acagtatcaa gatacagaac caactgtagc tcaaatggaa gaactaaagg
     8401 ttttggttgc tgatgaactt acaaaatacg cttcttcaat gttgcttgac cctgaatatg
     8461 gacttccagc aacaaaagca ttggataaag aagcaggtct tcttcttgcc tatgaaaaaa
     8521 caggttatga tacatcaagt acaaaacgtt tgcctgactg cttggatgtt tggtctgcaa
     8581 aacgtatcaa agagcaaggc gctgatgccg ttaagttctt gctttactat gatgtagaca
     8641 gctcagatga acttaaccaa caaaaacaag cttatattga acgtgttggt tctgaatgtg
     8701 tcgctgaaga tattcctttc ttcttggaaa tccttgctta tgatgaagaa atctcagatg
     8761 caggttctgt tgaatatgca aaagtgaaac ctcgcaaagt cattgaagcg atgaaagttt
     8821 tctctgatcc acgctttaac attgatgttc ttaaagtaga agtaccagtt aacgttaaat
     8881 atgtcgaagg ttttgctgat ggtgaagtag tttacagtaa agctgaagct gctgacttct
     8941 ttaaagcaca agaagaagcg actaaccttc catacatcta cctaagtgca ggtgtatctg
     9001 ctaaattgtt ccaagaaaca ttgcaatttg ctcacgactc aggtgccaag tttaatggtg
     9061 tgctttgtgg acgtgctact tgggcaggat ctgtagaacc ttacatcaaa gaaggtgaaa
     9121 aagcagcacg tgaatggttg cgtactactg gattcgaaaa tattgatgaa cttaacaaag
     9181 ttcttgttaa aacagctagt ccatggactg ataaagtata gtaaaaacat aaaacggagg
     9241 atattgttat gaacagagaa gagatgactc tcttagggtt tgaaattgtt gcttatgctg
     9301 gagatgctcg ctctaaactt ttagaagcgc ttaaagcggc tgaaaatggt gatttcgcta
     9361 aggcagatag tcttgtagta gaagcaggaa gctgtattgc agaggctcac aattctcaga
     9421 cagctatgtt ggctcgagaa gcttctgggg aggaacttcc atacagcgtt accatgatgc
     9481 atggtcagga ccacttaatg actactgtct tattaaaaga tgtgattcat cacctcatcg
     9541 aactttataa aagaggagca aaataatgca taaactcatt gaacttattg agaaagggaa
     9601 accgttcttt gagaaaatct ctcgaaacat ctatcttcgt gctattcgtg atggatttat
     9661 cgctggtatg ccagtcatcc ttttctcatc tatctttatc cttattgcct atgtcccaaa
     9721 tgcttgggga ttccactggt caaaagacat tgagaccttc ttgatgactc cttatagcta
     9781 ttcgatgggt atcctagcat tctttgttgg tggtactacc gctaaagctt tgacggactc
     9841 aatgaaccgt gacctacctg cgaccaatca gattaacttc ttatctacga tgctagcgtc
     9901 tatggtaggg ttccttttga tggcagctga gcctgcaaaa gaaggaggct tcttgacagc
     9961 cttcacggga acaaaaggtc ttttgacagc atttattgca gcctttgtga cagttaatgt
    10021 ttacaaggtc tgtgtgaaaa ataatgttac tattcgtatg cctgaagagg ttccaccaaa
    10081 tatctctcaa gtatttaaag acttgattcc attcactgta gcggttgttc tcctttatgg
    10141 atttgaactc attgttaagg gaactcttgg tgtaaccgtt gcagaatcaa tcggtaccct
    10201 tcttgctcct ctcttctcag ctgcagatgg ttaccttgga attacactta tctttggtgc
    10261 ttatgccttc ttctggtttg ttggtatcca cggtccttca attgtcgaac cagcaatcgc
    10321 tgctatcact tatgccaata tcgatgccaa cttgcatctt atccaagctg gacaacatgc
    10381 agacaaagtt atcacttctg gtactcaaat gtttattgtt accatgggtg gaacaggagc
    10441 tacattgatt gttccattct tgttcatgtg gatttgtaaa tcagaacgta accgtgccat
    10501 cggacgtgcc tcagttgttc caacattctt tggggttaat gagccaatct tatttggtgc
    10561 accaatcgta ttgaatccga ttttctttgt accgttcatt ttcgctccga ttgtcaacgt
    10621 ttggatcttt aaattctttg ttgacacatt gaacatgaac tcattctctg ccaaccttcc
    10681 atgggttact cctggtccgt tgggaattgt actcggtact aacttccaag ttctatcatt
    10741 tatcttagcc ggactcttgg tagttgttga tactatcatt tattacccat ttgttaaggt
    10801 atacgatgaa caaattcttg aagaagaacg ttctggtaaa acaaacgatg ctcttaaaga
    10861 aaaagtagct gcaaacttca atactgctaa agcagatgcc gttcttggaa aagcaggcgt
    10921 tgctaaagaa gatgtagcag caaacaataa tatcacaaaa gaaactaatg tccttgttct
    10981 ttgtgcaggt ggaggtacaa gtggcttgct tgccaatgcc ttgaacaaag cagcagcaga
    11041 atacaatgtt ccagtcaaag cggcagcggg tagttacggt gctcaccgtg aaatgttgcc
    11101 agagtttgac ttggttatct tggctccaca ggtcgcttca aacttcgatg atatgaaggc
    11161 tgaaacggat aaattgggca ttaaacttgc aaaaactgaa ggagctcaat atatcaaatt
    11221 gacacgtgat ggacaaggtg ctcttgcatt tgttcaacaa cagtttgatt aataaatttg
    11281 taaaagttat ttgagacgag attattcttt caattcctta taatattgtt aaccatatca
    11341 ttgcatttca tttccttggt ttccggaact cagaatatcg tctcaaatgc tttttttgaa
    11401 aggatttata gttatgacta aaacacttcc taaagatttt atttttggtg gtgctacagc
    11461 tgcttatcaa gcagaaggtg cgactcacac ggatggtaaa ggcccagttg catgggataa
    11521 gtatcttgaa gacaattatt ggtacacagc agagcctgca agtgattttt accataaata
    11581 tcctgttgat ttagaattag ctgaaaaata tggcgttaat ggtattcgta tttcaattgc
    11641 ctggtctcgt attttcccaa ctggctatgg cgaagtaaat gaaaaaggtg ttgaattcta
    11701 ccataatctt tttgccgagt gccacaaacg tcatgttgag ccattcgtga ctttgcacca
    11761 ctttgacaca ccagaagttc ttcactcaga tggagatttc ttaaaccgcg aaaatataga
    11821 acactttgta gattatgccg ctttctgttt tgaagagttc ccagaagtaa actactggac
    11881 aactttcaat gaaattggcc caattggaga tggtcaatac ttggttggta aattccctcc
    11941 aggcattcaa tatgatcttg ccaaagtctt ccaatcacac cacaatatga tggtttctca
    12001 tgcacgtgct gtgaaattgt ataaagataa aggttataaa ggcgaaattg gtgtagtaca
    12061 tgcgttgcca accaaatacc cttatgatcc agaaaatcca gcagatgttc gtgccgctga
    12121 gttagaagat atcatccata acaaatttat cttggatgca acctaccttg gacactattc
    12181 agataaaacg atggaagggg tcaaccacat cctagctgaa aatggtggag aacttgatct
    12241 tcgtgatgaa gacttccaag cacttgaagc agctaaagat ttgaacgatt tccttggtat
    12301 caactactac atgagtgatt ggatgcaagc ctttgatggt gagactgaaa tcattcacaa
    12361 tggtaagggt gaaaaaggaa gttctaagta ccagattaaa ggtgttggtc gccgaatcgc
    12421 accagattat gtgcctagaa cggattggga ctggattatt tatcctgaag gcttgtatga
    12481 ccaaatcatg cgagtgaaaa atgattatcc aaactacaag aagatttaca tcactgaaaa
    12541 cggtcttgga tacaaagatg agtttgtaga taataccgtt tatgatgatg gtcgtattga
    12601 ttacgtgaag aaacacttgg aagttttatc agacgcaatt gcggatggtg caaatgttaa
    12661 aggttacttc atctggtcac ttatggatgt cttctcatgg tcaaacggat acgaaaaacg
    12721 ttatggacta ttctatgtag actttgacac gcaagaacgc tatcctaaga aatcagctca
    12781 ttggtataag aaagtagcag aaactcaagt gatagagtaa tattacttga aaatgtaaaa
    12841 aattgttatc cgatacttta gaaaaagtac aacacttatt tagaccaggc tttgaaaagg
    12901 tatatattgt tagtttcgaa gattgtccta tgattcctga gcttgaagct accccgttgc
    12961 taaaatgtgg taaatggtat gtttcaactg gaaaagagtg gatttgccat tctgatttag
    13021 agttatcagc atttgaatgg gaatttttac aatcactcga tgtagaaata cgtgagacta
    13081 ttcacttcga ggtaaattat ttgcctttcc aataataaaa agaaaggaat tagttgtgac
    13141 tatcgaatta aaaaacgagt atcttactgt tcagtttaaa acacttggtg gtcaactgac
    13201 ttcgattaaa gacaaggatg ggatagagta tctctggcaa gctgatccaa attattggaa
    13261 tggacaggcg cctattctat ttcctatctg tggtagttta cgaaatgatt gggctattta
    13321 tagacctcaa gaaagaccct tttttacagg tcttattcgt agacatggtt ttgttcgaaa
    13381 agaagaattt attctggaag aagtcaatga taatagcgtg acctttagta ttaaaccaaa
    13441 tgctgagatg cttgataatt acctatatca gtttgaactg agagttgttt ataccttgaa
    13501 tggtaaatca attagaaccg aatttcaggt aacgaacttg gaaatggaaa aaacaatgcc
    13561 ttactttatt ggagcccatc cagcattcaa tagtccttta gtagaaggtg aaaactatga
    13621 ggattattat attgaattta gtgaggttga gtcttgctcg ataccaaaga gttttcctga
    13681 gacaggatta ttagatttgc aagatcggac accttttttg gaaaatcaaa aaattctcga
    13741 tttggactac tcactttttt cccatgatgc cattacactt gaccagctca agtctcgtag
    13801 cgtaacgctt cggtcaagga agtctggtaa aggtcttcga gtagattttg atgattttcc
    13861 gaacttgatt ctgtggtcta caactaataa aagtccattc attgctttgg aaccttggag
    13921 tggtctctcc acttcacttg aagaaggtaa tttcttagaa gataaaagac aggtaacgaa
    13981 aatttcacct caagaaactt ctagaaaaat ctatgatatt actatcctta attaaaattt
    14041 gttattattt gagtcttcaa taagatttga atactcttac cttgtgatga tagattggtc
    14101 ttctccgtgc cagtcttaca tcgcaaggtt tttaagtttt ttgtgggtct atgtcaactg
    14161 tagtgggtga cgaaaagcta atatctaaag acagtctggt agtaaaaaat aagattattt
    14221 actacttctt gatttaaaat aatagtggag ccattaattt gtggcaaatt taatttaata
    14281 ttttgcctca aattagccac actttttata gaactaagag gaaaaatgaa attttcttcc
    14341 tattaatata gttgtttgaa atcttaaata tagcgt
//
LOCUS       DAFTHM010000067        14161 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFTHM010000067 DAFTHM010000000
VERSION     DAFTHM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.067"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            66..767
                     /locus_tag="L7C88_001941"
     CDS             66..767
                     /locus_tag="L7C88_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBP9558753.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            764..1885
                     /locus_tag="L7C88_001942"
     CDS             764..1885
                     /locus_tag="L7C88_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBP9558754.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            1900..3132
                     /gene="pepT"
                     /locus_tag="L7C88_001943"
     CDS             1900..3132
                     /gene="pepT"
                     /locus_tag="L7C88_001943"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBP9558755.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            3264..4172
                     /locus_tag="L7C88_001944"
     CDS             3264..4172
                     /locus_tag="L7C88_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBP9558756.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            4207..4479
                     /locus_tag="L7C88_001945"
     CDS             4207..4479
                     /locus_tag="L7C88_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBP9558757.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            4490..5536
                     /locus_tag="L7C88_001946"
     CDS             4490..5536
                     /locus_tag="L7C88_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBP9558758.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            5787..8396
                     /gene="clpB"
                     /locus_tag="L7C88_001947"
     CDS             5787..8396
                     /gene="clpB"
                     /locus_tag="L7C88_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBP9558759.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(8547..9233)
                     /locus_tag="L7C88_001948"
     CDS             complement(8547..9233)
                     /locus_tag="L7C88_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558760.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(9211..9705)
                     /locus_tag="L7C88_001949"
     CDS             complement(9211..9705)
                     /locus_tag="L7C88_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBP9558761.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(9725..10945)
                     /locus_tag="L7C88_001950"
     CDS             complement(9725..10945)
                     /locus_tag="L7C88_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9558762.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            11092..12927
                     /gene="lepA"
                     /locus_tag="L7C88_001951"
     CDS             11092..12927
                     /gene="lepA"
                     /locus_tag="L7C88_001951"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBP9558763.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(13021..14148)
                     /locus_tag="L7C88_001952"
     CDS             complement(13021..14148)
                     /locus_tag="L7C88_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBP9558764.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT         4575 a         2602 c         2927 g         4057 t
ORIGIN      
        1 ttttttattc ctagtctcct tattttattt ggaaaatgct ataattatct agaaggagtg
       61 aagctatgaa ccatttagat ttatctcagc gcttagccgc agtgggtgac tttgtccctg
      121 aatccgctcg tttagcagac attggatcag atcacgctta cttacccgtt gcattgatat
      181 taagaggaaa aatcgaatat gcagttgctg gtgaagtcgt tcaaggtcct tatgaatcag
      241 cacgtaagca agtcaaaaaa gatggattag aagaccgtat caccgtacgc cttgcaaatg
      301 gtctagatgc tatccagcca caagatggta ttacagctgt cacgattgcg ggtatgggag
      361 gttcactgat ccgagatatc ctagaagctg gcaagttgaa tcaacgctta agcggacaag
      421 aacgtttgat ccttcagcca aacatcggag agcgtacatt acgatcttgg ctgcaagaaa
      481 atcagtataa aatccaatca gaaaaaatac ttgaagaaaa taaaaaaata tatgaaatca
      541 ttgtagccga aaaagaacaa aaaccagtta cttacaatga aatggagctg atgttcgggc
      601 catttctgct tgaagagaaa agtgagatct tcaaatcaaa atggacaaga gagcttcaac
      661 aaagaaaagc tatccgtgaa cagctcaaac aagcagctaa tcaagaggca cgtcaaaaac
      721 aaatcgagca ggaaatccaa atgattgagg aggttttaaa gccatgacaa tcagcggacg
      781 cactttcatc caaaagtttg aaagctattg tcctcagtgg ctagctgaag aaggagaccc
      841 agtcggactg catatcggaa cattggataa gccaatccaa cgagtaatga tgacattaga
      901 cgttcgtcca gaagtggtcg aagaagcaat caagaaaaaa atcgatttgc tgattgctaa
      961 acatcctcca atctttcgtc ctgtaaaacg gctggttact gatcagccac aagaaaaaat
     1021 gtatgcagat ttgttgaaac atgatattgc cgtctatgca gcacacacga acatggatat
     1081 tatttgggat ggactgaatg actggttttg tgaacttctc ggtattgaag tggagagtta
     1141 tttagtaaag actcatgaga ttcattataa aaaactggcc gtttatgtac ctgtggatca
     1201 tgcacagaaa atgcgtgaag tattagctgc agctggtgct ggtacacaag gtgattatac
     1261 cggtacaagt tttacctcga ttggacacgg tcgatttact ccggaagctg gtgcacaacc
     1321 agcgattggg aaagtaggga agacagaaca agttcaagag gcaaaagttg aggttatttt
     1381 gccggaaact atcgaaaaac aagtgattca agccatgcgg tcagctcatc cttatgagga
     1441 acctgcttat gatcttttcg ctatagatga accagtcgaa atgtttgggt taggacgagt
     1501 aggtgaattg ccgcaagaaa tttctataga ggcatttgta gaacaagtaa aagaagcgtt
     1561 ccaactagat ggactgagaa tagtccagcc aaaaaatgca aaatcctctg tgaagcgcat
     1621 tgcgatttgc ggtggaagcg gtgaaaaatt ttatccgcaa gcaatcgccc aaagagcaga
     1681 tgtctatatc acgggagata tctattatca tacggctcat gatatgcaaa gcgctgggtt
     1741 gattgcaatt gatcccggtc attatattga atcgttatgc aagcaacgat ttatcgagaa
     1801 atttgaatct tggaaacaag aagaaaattg ggatattaac tttttcgttt ctgaaacaaa
     1861 tacaaaccca tttcaattta attaaaagga gagaatacta tgtacgaaaa tcttttgcca
     1921 cgttttttac gatatgtcaa aacagaaaca cgctccgatg caacaagcaa aacgactcca
     1981 tcgactcaga cacaagttgc ttttgcgcaa gaattgaaaa aagaattaga agagttaggc
     2041 ttagctgatg ttttctataa tgaagataac ggattcgtta tgggaacatt accaagcaat
     2101 gttgatcatg aagtgcgttc cattggattt atttcccaca tggatacagc agattttaat
     2161 gcagtaggag tcaatccaca aatcattgaa aactatgatg gcgagtctac gatcgtacta
     2221 gatgcggaag aacgctatac attgaataca aaagattttc caaatttgaa aaattatgaa
     2281 ggccacacat tgatcacaac agatggcagt acattactgg gagcagatga caaatcaggg
     2341 attgcggaaa tcatgactgc aatggagatc ttgatcaata atccttctat ccctcacggt
     2401 accatcaaag tggcttttgg tcctgatgaa gaaatcggtg tcggagcgga taaattcgat
     2461 gttgagcaat tcgatgtaga ttttgcttat acagtcgatg gtggtccttt aggtgagttg
     2521 cagtatgaaa cgtttagtgc tgctcaagca aatattacga tccaagggaa aaatgtacat
     2581 ccagggacgg caaaagatac aatgatcaat gctctacagt tagcaatcga ttttcataat
     2641 cagcttccag ccgatgaagt tccagaaaaa acggaaggat acgaaggttt cttccatttg
     2701 atggcattgg atgggaatcc tgaagaagct tctatgagtt atatcattcg cgatcatgat
     2761 cgtgaaaaat tcgaagcacg caaagcacaa atcacacata tccaagaaga gttgaatcag
     2821 cgatttgatc aagaacgaat caaagtagat atgtatgatc aatattacaa catgaaagaa
     2881 atcattgaaa aagatatgag catcgtggaa ttagcgaaac aagcaatgat cgagcttggt
     2941 atctctccag tgatcgaacc agttcgtgga ggaacagatg gttcaaaaat ctcttacatg
     3001 ggtattccga cgccaaatct atttgccgga ggagaaaata tgcacggacg attcgaattt
     3061 gtttctttac aagtaatgga aaaagcaaca gacgtgattg taaaaattgc agaattgaac
     3121 acaaagagtt aaaatcgaaa aagaacagct tatgacaagg cgttcgtccc aatgatggaa
     3181 tgtcatctgt ctaaggctaa agggcaggac aatggaattg gttgtcccgc cctctttttt
     3241 gaagagtaaa taggaggtaa agaatggaaa agctgctagt tttttataac aaaagttcag
     3301 ggaaagatga gggtgagaaa ttagcacgct ggtttcaaga ttatgtaaaa gaaaagcagc
     3361 cagaattata tgtagaacta gctgaaactg gcccatcgat tgatgatgcg gaattagtca
     3421 agaaagcaga agccatagaa gctgatactt tagtaattat aggtggagac ggcacgattc
     3481 atcatatcgt ccaagcgttc caaaaaacat tatctcaata ccatgtcgga ttacttccag
     3541 gtggaactgt caacaacctt gcacgtgttc ttgagattcc cctcaaaaaa gaagaagctg
     3601 ctgacgtgat cctggaaggc aatgtacgga aaatagacta tggtcaagtc aatgatgaag
     3661 tcattatctc tacactgaca atcggaatct tagcagatac agcagtttgg atcagtcaag
     3721 aagaaaaaca gcgttacggc tcgtggatct ttatcaagaa gttttttaag ttattgctga
     3781 agaagaaaaa atatcatttg gatttagaaa cagacgagga gcattggaaa ggaaaatccc
     3841 aactgttgac agtcacgatg tctaactccg tgggcggttt tacaaatttt gacgactcag
     3901 cgaccctaga tgatggaaaa tttcatgtaa cgatcgtacc ttccttagat attttccgat
     3961 ttatttttta tttgcctaga atcatgagag gcaaattcta tacgatcccc ggcattactt
     4021 atttcacagc caaacgcatg aaaatccaag cgcaggaaaa atctgtgggc actcgaacgg
     4081 atggagacac gacagatgat cttccagttg aattatctgt tgtatcaaaa ggattaacag
     4141 tttattcacc aaagaaagaa gaaaaagctt agaaatagta gttaacagaa agttggaaga
     4201 agagtaatgg atgtattgtt acacaatctt ttgtggtttt accttttcat tgtgaatttt
     4261 tacttatttt gtctgatggg gtatgataaa catcaggcta gaactagcgg ctggcgtgtt
     4321 cctgagaata atttgatatt tgtcagcctg ttaggcggtg gtttgggagg attgatctct
     4381 cgaaaagttt tccatcataa aactcggaaa aagaagttta ctataggatt cgctgcaggt
     4441 gtacttgttg atttgattct catttatttt ttccattaag gagcaggaga tgtcgtctaa
     4501 aggaacgaaa actaaaatca ttctgaatct gcttttgctg attgtgattt ttgccattat
     4561 ttattattta atcaatcaat catttgcaga tatctttgcc gaattgctgt ctaccagtgt
     4621 tgttgttttg gcagcggctg ttatattagg gacagtttac caaatcgctg aagggcgctc
     4681 aatcaaagaa attgctgaac ctttcgcgcc gaattttaca acgaaagatg ggttcttgac
     4741 ctctagctat attgcgtttt accgaatcgt ttcgtttggt acaggaacgc tgatctcgga
     4801 gatttatttt tataacaaaa aaggaatgaa gctatcccag ggagcagggg tgacagcact
     4861 ccatatgatt atgtacaaac tggcagtgat cacttatgca ttagctggct tggtcatcca
     4921 attctctctt ttttattcta atggtccatc aatgatctgg tttatcatcg ctggtatcct
     4981 tttgacgatc gtgattgttg cctttttatt ggcgatgtcc gtcagcttga atgttcaaat
     5041 attttttgtc agcttatcga ataagttatt taaaagtgag cgtttgcgga aatgggtgga
     5101 tacatgcaat cagcagatct actctttaag ggaaacggtc caaaccatta tccaagacag
     5161 gactgcgcta ttgcggattt atctatggaa tatgttaaaa cttgtatttt ggtatgtact
     5221 tccttatttg attctgattg aaaaccatcc taaaatagat tttctactga ccatttcgtt
     5281 tatcagcttt gcagtagtgc tttcaggggt tattcctacg cctgctggta ttggttcctt
     5341 tgaatttgtc tatttgttat tattcagacc agttgttgga acagttgacg cagtttcttc
     5401 gcttttactg tatcgtttca gttcctttat cttgccattt ctctatggat ttgtgtatgt
     5461 gattgctgaa cggcgaagag tgatcaaaga agaaataata gaagtaaaaa aagagaataa
     5521 agaaaatcaa gggtaggtct tttataagat ctaccctttt tatcaaatca aagaaaaacg
     5581 ttatggataa gataatttta cgtttgtttg gctctttttt tatatacata caatcaattt
     5641 tgttttttta agatttatat aagtcgagaa aaaaagtcaa aaaactatgt gtatattttg
     5701 accaaaattg accaaagcga tataatagtt tttgtaaaga tcaaagaaat aagtgatctt
     5761 acctttaatt aggagggtat acctgtatga atattgagaa aatgactacg acgcttcaag
     5821 aagcgattgc tgaagctcaa cagattgcgg tcactcgaaa acatcaagat atcgacattg
     5881 cccatgtatg gaaaatcttt ttacaaccta atcattttgg tcgaaatttc tatacggatg
     5941 ccggattgga tgtcgaatct tttgaacatg aaattgatcg tctactggat gagtatccag
     6001 ttgtttctgg tggaaacgtc caatatggac aaaacctcag ccagaatttc tttcgattat
     6061 tgaatgaagc agaccaaata cgtgaaagct tcggcgacga gtttctttca acggaagtcg
     6121 ttattttagc gttgatgaaa ttaaaaaatt atccgttaac tgtttatttg aataaaaacg
     6181 gattatctga aaaagaattg cgtaaaaaca tcgaagagat gagaggagga gaaagagtga
     6241 cctcacaaaa ccaagaagaa caatacaaag cattagaaaa atacggcgtt gatttagtac
     6301 agcaagtcaa aagcggaaaa atggatccaa tcatcggtcg tgatgaagaa atccgtgatg
     6361 tcatccgtat tctttcacga aaaacaaaaa ataatcctgt tctgatagga gaacccggtg
     6421 tagggaaaac ggcaatcgtt gaagggcttg ctcaacgtat cgtacgcaaa gatgtgcctg
     6481 aaaatttaaa agataaaacg attttttcat tagatatggg tgcattgatc gctggagcaa
     6541 aattccgtgg tgaatttgaa gaaagactaa aagcagtctt gaaagaagtc aaaaaaagtg
     6601 atggacgtat cctcttgttc atcgatgaaa tccacaatat cgtaggggca ggaaaaacag
     6661 aaggaagtat ggatgccgga aatctgttga aaccaatgct tgctcgcggt gaattacatt
     6721 tgatcggtgc cacaacttta gatgagtacc gtcaatatat ggaaaaagac aaagcgttgg
     6781 aacgtcgctt tcaaaaggta ttagtcaaag aaccaacagt ggaagatacg atcagtattc
     6841 tgcgtggatt aaaagaacgt tttgagatcc accatggtgt taacatccat gacaacgcat
     6901 tagtagcagc agctacttta tctgaccgtt atattactga tcggttctta ccggacaaag
     6961 caatcgattt gatcgatgaa gccagtgcaa cgattcgggt agaaatgaac tctatgccaa
     7021 cggaattaga tcaagttact agacgtttga tgcagttgga aatcgaagaa gctgcactga
     7081 aaaaagaatc agatgatgca agtaaaaaac gcttgaaaaa tttgcaagaa gaattagctg
     7141 aacttcgtga agaagcaaat gcgatgaaga tgcagtggga aacagaaaaa gaagaagtca
     7201 attctgtttc agcaaaacgt gctgaaatcg ataaagcaaa acacgaatta gaagatgcag
     7261 aaaataacta tgatttagaa cgcgctgctg tattgcgtca tggtacgata cctcaattag
     7321 aaaaagaatt gaaggaatta gaagctaaag caaaagacag cgagattaag atggttcaag
     7381 agtccgttac cgaaaatgag attgctcaag tcgttggcag attaacgggt atccccgtaa
     7441 cgaaacttgt agaaggtgaa cgagaaaaac taattaaatt gaatgaaaca cttcataaac
     7501 gagtgattgg tcaagatgaa gcagttgatg cggtcagtga cgcggtaatt cgttcacggg
     7561 ctggattgca agacccaaat cgtcctctag gttctttcct tttcctagga ccaactggtg
     7621 tcggaaaaac cgaattagcg aaagcgttag ctgagaactt gtttgactca gaagatcata
     7681 tggtacggat cgatatgagt gaatatatgg aaaaacatgc tgtgtctcgt ctagtcggag
     7741 ctcctccagg ctatgtaggt tacgaagaag gtggtcaatt aacggaagct gtcagacgaa
     7801 atccttatac aatcgtcttg ttggatgaaa tcgaaaaagc gcatcccgat gtcttcaata
     7861 tcttgttaca agtcctagat gacggacgct tgactgattc aaaagggcga gtagtagatt
     7921 tcaaaaatac ggttctgatc atgaccagca atatcggttc acagttactg ctggaaggcg
     7981 tgactgctga tggaacgatt ccagaagcag tggctgaaca agtcaacacg ctattacgtg
     8041 gaaacttcaa accagaattc ttgaaccgaa tcgacgacac gattttattt acaccattga
     8101 gcctagacaa cgtgaaagga atcgttgaca aaatggtggc gcaattggca caacgtctgg
     8161 aacatcaaga aatcctgctg acaatcagtg atgaagccaa aacgtggatt gctgaaaatg
     8221 cttatgaacc agcatatggt gcaagaccat tgaaacgatt tatcactaag gaagtagaaa
     8281 caccactagc taaagaaatc gttgcaggac atgttatgcc taaatcaaaa gtaacgatta
     8341 ctttacttga tggacaactt catttcaaaa cagaagagct agaagaaatc gtctaatctt
     8401 ccattgagac tataaaagaa aaaaggggtc tgacacaact agtgtcagac ctcctttttt
     8461 caaataaaca gtgttccaga agtagtttct tcgaaaaata agccgaaatt tcttgaagct
     8521 gcccgcttct gtcacaacct cttttattag gtatttttca ctttttctaa tttataactt
     8581 tcaaagtaac gctcatcttt tttactttga gaccatgcaa acaatcccat taaggcagca
     8641 cctatcgtat ttgtcagcaa gtcgcccatc gtatccatca atgctgctcg tccgacaaac
     8701 agtgtgccat cagaagcagc aaaacgttga agattcatgc ctaagaactg gtcgcataag
     8761 aattcccaga actcccaaaa cacgccgcaa agtccagcaa acgcaaagcc gaataagagg
     8821 aacaaccaag gactggtttt tgatatctca gcatctttca tcaagtaacc aatcaatcca
     8881 tagccaagag ctgtcaggac cattggactc accgcatgta agattttgtc ccaaaaagag
     8941 atgatactga tcaaatgcat ccctgtgcct aaaaagacag agatgaacaa gaaaaaccag
     9001 taaaacaaaa cgattgctgc tggtatttta agtttgaaaa ctttcaaaat gacttgtggc
     9061 atgaaaatca atgcaatccc taataaagat tccacgataa atgtgattcc ttgagaagtc
     9121 gaatattttt gtgtgataaa ttcataaaaa ttatagcaga caacgaatac accaaaagca
     9181 agtaaagcta tttgcacctt tttgatttct ttaatcactg aaagtccctc catctaaaaa
     9241 tctttttact tctgaaagca actcaatttc tgaagaaacc acttttccgt tcaatttgat
     9301 caaacctatt gtatataagt tcaggtagtg aaattgattt tcagctgttt cttgtagtgc
     9361 agcgattttt ttcgggtggg ttccgccttg ctgtcgagta tcagtatata agccgatcac
     9421 tgggatgcct ttcgcataag ccacaccgat ttccgatgct accccggcat cgatcgtcag
     9481 cccatctagt aaagcaatca ttaaatcact agccaacact ttttctgtgt cagcaagagc
     9541 aatcattcga ctgtctgcat aagcagtttt gtcattgatt gcttcatttt cttgaggaag
     9601 atagatcgaa agctcagaag agagctctct gatttcttta actaactgtt ggttatataa
     9661 caaatcactt ttagcaaaca ttggtgcggc aaaataaatt ttcatctaaa catcatcctt
     9721 tttatcaaaa ataatcgcta aagtaagctt ccatgtttgg aatgatacgc tctagtgact
     9781 tcagtgtttc ttcatctgtt tctaaccgtt cgattcttgc caaataagaa gcacggcgat
     9841 aattcatcat caagcaagtc aatgtttgga tatccagtcg aacggatttt cctataggtt
     9901 catttaagac acggacttgt ccctgttcat cccatgttaa agcgaagaca ccattattcc
     9961 aaggagcgac aggatcttca atgatgaaat gaaaagcatc agctgttcca acaaacggaa
    10021 accgttgaag gaattctttt acatcaacga tccgagccat aaaatatggt tcgatctgct
    10081 ctttgatctg actatcttca atcaaaaatg ctaaaggctc atttttataa atatctccat
    10141 gtacccagta gatcatggaa aaatgtgcgg aaataaagtt ccataagcca tttcgagctt
    10201 cttgatcaag atagaacatt tcttttacgt gaaatatttc ttcagctacc caatagaaca
    10261 gaacacctct tggttcatgg ttgctatcgt agtagacagc ggctgtgcgc tcatcttcat
    10321 tttcgaaacg ccaatactct tcccaatgaa aatcactgcg gaataaagca ccatggtttt
    10381 gttgggcaaa tttgtcataa acggaaaata cgtctggatg atcaactggt aatcgctcaa
    10441 ccataccact tactgggatt tgtttaggta gctgtgtatc tctgatttta aaggaaagtt
    10501 tatcagacat gatttcccat cctttacgcc gatagtaggg gatactgtaa ggatacaaat
    10561 aagagatcca ttgcttattc ttgcgcatat tatccaatgc aacgataatt agatcttgca
    10621 tcaatccatg gttagcatat tctggataag ttccaactcc agtcacacca cccattttat
    10681 aacgtgcacc gtgaatattg acttcacaag gatagatagc gatttgagag atcagtttat
    10741 tttcgtggaa ccatccgaac actttcgata cttccaaaat cggttttttg gaacggataa
    10801 aagctcgttt attctcaaac ccgctttcct cgatgtctgc ttcagtcact tggaacacat
    10861 aggaaagcaa ttcattgaat tgatcgatat gttcttgagt gaccggtttt aattcaagat
    10921 tttctctaaa atctttttga tccatttttt catctccatt tattagcttg ataacagtat
    10981 agcaaaattc tacaaaaaaa acttctatag ctgactaatt aaaaactctt taaattactg
    11041 cttttcgttg gtataatgga aagtgctgat tatatgaaaa gaggagacgc tatggatata
    11101 aagaaaatga aagaacgcca agagcagatt cgtaattttt cgatcatcgc tcatatcgac
    11161 catgggaaat ctacattggc cgatcgtatt ttagaaatga cgcacactgt gacgtctcgc
    11221 gaaatgcaag atcagctgtt agactcgatg gatttggaac gtgaacgtgg aatcacgatt
    11281 aaattaaatg ctgtagaact caattacaca gcgaaaaatg gagaaacata tatctttcac
    11341 ttgattgaca ccccagggca cgtcgacttc acctatgaag tctctcgaag ccttgctgcc
    11401 tgtgagggtg ccgttttagt ggtcgatgca gcacaaggaa tcgaagcaca aacattggcc
    11461 aatgtttatt tagcgttaga caatgatttg gagatcctgc cagtcatcaa taaaatcgac
    11521 ctacccgcag cagatcccga acgtgtccgt caagaaatcg aagacgtaat cggaatcgat
    11581 gctagtgaag ctgtattagc cagtgccaaa tcagggattg ggattgaaga tattctcgag
    11641 cagatcgtgg aatatgttcc tgcaccaagt ggagacttag atgcaccgct aaaagctttg
    11701 atctttgact ctatttatga tagttaccgc ggtgttgttc taaatgtccg gatcacggac
    11761 ggtatggtca aacccggaga caaaatcaaa ctgatgagta atggcaaaac atttgatgtt
    11821 acagaggtcg gggtcttctc gccaaaagca gttgctagag actttttgat ggtcggtgat
    11881 gtcggttata tcacagcaag tatcaaaact gtccaagata cacgagtagg ggatacagta
    11941 acgttagcag acaatcctgc cgctgaagct ttaccaggtt accgaaaaat gaatccgatg
    12001 gtttattgtg gtctttatcc aattgatact tctcgttaca acgatttgcg ggaagcttta
    12061 gaaaaactgc aattgaatga tgctgcttta caattcgaac cagaaacctc tcaagcatta
    12121 ggttttgggt tccgctgtgg attcctcgga cttcttcata tggatgtcgt ccaagaacgc
    12181 ttggaacggg aattcaatct agaattgatc acgactgcac catccgttat ttaccatgtt
    12241 aataaaacgg atggtacgac tgctacagta gataacccgg cagattttcc tgaacctgta
    12301 acgattcagg atgtagaaga accattcgtc aaagcacaga tcatggtccc aaatgatttt
    12361 gtcggtgcag taatggaact ttctcaacga aaacggggag aattcattac gatggattat
    12421 ttagatgatt accgagtaaa tgtcgtctat aatattccgc tttctgaaat tgtctttgac
    12481 tttttcgaca aattgaaatc aagcacgaaa ggctatgcct cattggatta tgaaatgtct
    12541 ggttatcaaa aaagcaagtt agtgaagatg gacatcttgc tgaatggaga aaaagtcgat
    12601 gcattaagct ttatcgttca ccgagacttt gcctatgaac gtggaaaagc aatcgttgaa
    12661 aaactgaaaa aactaatccc acgccaacaa tttgaggtgc caatccaagc agctattgga
    12721 caaaaaatcg ttgcccgttc agacatcaaa gccttgcgta aaaacgtctt ggctaaatgt
    12781 tatggtggag atgtttctcg taaacgtaaa ctcttagaga aacaaaaaga agggaagaag
    12841 cggatgaaac aaatcggctc cgtcgaagtt ccgcaagaag ccttcatggc cgttctgaaa
    12901 atggacgagg acgaaccgaa gaaatagcaa gggtttgttt gaaaacagtg taaaaaataa
    12961 accatgttta catggatttg ccaccggttt gccaccggtg gtttttttcg gtggcaaaaa
    13021 tcaagaattc tttctaagat tttccatgat atcgaccgtt tcatttctca tcttatctgt
    13081 tacatgcgag taagtatcca tcgtaattga aattctgctg tggcccaatc gttcagagat
    13141 ttctttcatt tttgcgccat tttcgagaag aagtgtagca tgagtatgtc tgagagaatg
    13201 gaagttaaaa gagagggaga gtgcattcga tatcctccta gtattccatt tcactacact
    13261 tggcgtaact agctcaccgt cttccttcgt acatactgca tttgaatcaa tgtagagctt
    13321 tccatacttc attcgatttt ctaattgttg tttcttatgt tttttcagaa ttgctagcaa
    13381 ggtttgtcca ataaaaatcg ttcgattgga actgcttgtc tttggcgtac catataccca
    13441 tgcgccgtca ttctttacca tttgtttctc tacagtaatt gttccatttg aaaaatcgac
    13501 atcatcccac gtcagaccac aaacttcgcc aacgcgcatt cccgtataaa atccaatatt
    13561 caaaggaata tagaaaggat gtccttcagg agtaatttct agcatatgat caaagtcctc
    13621 aagagaaatg atttttagat cttttttagt cgttggtcgt gcttcatatt ttggtatttt
    13681 tacatacagc ataggatttt gcttgattaa tccccaagga taaaccgcca tattcagcgc
    13741 attcttaagg acagagtgag taatagtcat tgttttcttc gagtaaccct ttttaaattc
    13801 agcattgatg aaattttgta aaagagcagg ggagagatcc gtaagttttt tctttcctaa
    13861 ataaccgttt atatgatttt tgatggtaaa tcggtagttt tcataggtat tgtattttag
    13921 atttagttta acgtattcct ccatccaaaa atcaaggtat tgttttactc gagtatccgt
    13981 acctaaaaag tattgtcctg tttcgtcaat atctgataaa acttttcgta aagcagcttc
    14041 ggcctctggt cgggtgtctc cgccaacttt ctccactttt tttcttgagc catcatcatt
    14101 gatatcttcg ccgtttgtat aattaagcga gacaaataaa aaagccattt atgttacact
    14161 c
//
LOCUS       DAFTHM010000068        13732 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFTHM010000068 DAFTHM010000000
VERSION     DAFTHM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.068"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(143..1345)
                     /locus_tag="L7C88_001953"
     CDS             complement(143..1345)
                     /locus_tag="L7C88_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBP9558765.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1348..1542)
                     /locus_tag="L7C88_001954"
     CDS             complement(1348..1542)
                     /locus_tag="L7C88_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBP9558766.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1589..2437)
                     /locus_tag="L7C88_001955"
     CDS             complement(1589..2437)
                     /locus_tag="L7C88_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HBP9558767.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2642..2992)
                     /locus_tag="L7C88_001956"
     CDS             complement(2642..2992)
                     /locus_tag="L7C88_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558768.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3587..4033
                     /locus_tag="L7C88_001957"
     CDS             3587..4033
                     /locus_tag="L7C88_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBP9558769.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4657..5649
                     /locus_tag="L7C88_001958"
     CDS             4657..5649
                     /locus_tag="L7C88_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9558770.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5665..6549
                     /locus_tag="L7C88_001959"
     CDS             5665..6549
                     /locus_tag="L7C88_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9558771.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6598..8205
                     /locus_tag="L7C88_001960"
     CDS             6598..8205
                     /locus_tag="L7C88_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBP9558772.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8206..9690
                     /locus_tag="L7C88_001961"
     CDS             8206..9690
                     /locus_tag="L7C88_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBP9558773.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9867..10859
                     /locus_tag="L7C88_001962"
     CDS             9867..10859
                     /locus_tag="L7C88_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9558774.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10911..11780
                     /locus_tag="L7C88_001963"
     CDS             10911..11780
                     /locus_tag="L7C88_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBP9558775.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12200..13693)
                     /gene="guaA"
                     /locus_tag="L7C88_001964"
     CDS             complement(12200..13693)
                     /gene="guaA"
                     /locus_tag="L7C88_001964"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBP9558776.1"
                     /translation="MITRRIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYD
                     EKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALF
                     QNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSE
                     YGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVL
                     LQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDP
                     EEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVG
                     GLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEK
                     LEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSI
                     DGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE"
BASE COUNT         4214 a         2322 c         2832 g         4364 t
ORIGIN      
        1 ttgaaaaacg ttgatttatc ggcattcccc atccatatta tatttacgtc ttattcccac
       61 tcaatatgag tagcctcgta aagaagctat tatatcagtg ctttttcagc ctattcctca
      121 ttttggtagg gaaatggtag ggttagattt ttactgcttg atttccatta aagtttgcaa
      181 ctttagattt tgttgcacag gtaaatttaa tgtttcctgt catttgttct gcaattcctt
      241 catcattacg gctccataga tgagcgtagt gctttaaagt gatttcaggg ctagaatggc
      301 ctaaccgttg cgacacgacc agaatgtctg cgttaaactc attgattagg tagctaacat
      361 gagaatgacg taatcctttt ccttgtatta ggggtacctt agctagtttg gcataacgct
      421 gaataattcg ttgaacagtt gaacgataga gtgggaggtc agtgtagcta agaataaatt
      481 gttctacacc atgatttttt tgaataactt tccacttttt tagcacttca attgtatcat
      541 cgtccagaga aatgatccgc aagccgcttt cagtttttgt gtaaggtttc cgaataaaat
      601 ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca
      661 cgtcattcca attaagtgct aatccttcgc ttacacgaac accagtcatg taatatagcc
      721 agatcattaa aaaacacata tgttcgtaga aatcatcttt ataaattttt gccaaaactt
      781 cttcaaattc ttcttttgtc cagtaaggaa cgattgattt tccttttgga attgcttttg
      841 ttcttttgga aatattctca ttcagaaatt gcagggtgac cgcatagtct aatgatttac
      901 gaaacatacc gtacataagt gaactgtatg cttgtgagta tccgctatcg ttcaataacc
      961 aaattcgata attttcacaa tctcgcacat tgatttcacg aagcttctta tcaccgaaaa
     1021 attcagtaat ctgaatcaat ccacactcac gagaactcca agtacttttt tgtacgctag
     1081 ctttgtagtg tggaacgtaa gactgctcca taaattcttt gtaagttaaa tcataattcg
     1141 caaatccatt tacaaccatg tattcatttt ttatacgcat gacttctttg tgtgcttcac
     1201 gagctgatga gaatcgtttt cctagagaat cttttgttcc tttcttctgg atcctctttc
     1261 cagtcacttg atctgttcct aactcaacta gataagaaaa gcgaccattt ttatcttgat
     1321 acacacaagg gtattttgtt ttcatagtta ttcctcctgt gaaagaggaa cacctataat
     1381 ttcttcaatt acttgtcggg gtactacccc aactctttta ttattataat atggatatcc
     1441 ctgatttacc attcttgttt ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa
     1501 tcctagagcc tctaaatctt ttcgacaaat tgtatttttc attgtataaa ctcactttca
     1561 aagaaaacac tatcattggg taatagtgtt atttctttat ttttgtataa tgaacggtac
     1621 tttcttgaaa atccatcact tgttcaggac ttcccaactc atttaaagct aaagcattgt
     1681 aaaaaaatgg acgtctaact atatattcgc ttgtatatag tatatcttga ttcgtggaat
     1741 catagggttt ctttaccatc tttttggtga cagttggtag tttgagattc cgggacttga
     1801 aaaaagcttt tttcttatgc tctttcaatt ccagctcttt atcgaaatat ttgctgatat
     1861 agcgcccgcg attttcgata ctgtctacat cgatcttgtt gatcttaacg aaaccctgac
     1921 cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa atcaaacaag ataatatggt
     1981 agtggattgc accgcgttgc tgcttttccc acgtggcgag atactttaaa tttgcttttt
     2041 tagttttata gaggtcataa ttcagtcgtt tgataaattt tttaaattca ttatttgcat
     2101 actcaatgtc ttgaatgttt tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa
     2161 aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact ttgataatgt ttctgtttgc
     2221 gttttaaact gtcatattgt ccttgagcgg ataattcatc atagtttttt cttttttcaa
     2281 gagtaatatc attttcataa atccaagcta atttttgttt tcgttccaga tttacttcgt
     2341 tttcgatcgt tttacgtttg ggagtaatga ttgcttcata atcataaatt tcaatatacg
     2401 tgggagtttc aatgattttc tgattataag cttgcaaaaa tcatcactcc ttgttgcgta
     2461 ttcgattgtc aaagaaccag tcattttctc ctgatgttga tctataaatc aagttaaggg
     2521 ggaaggcctg cgtagcagcc cttctagcct atggggtgtt gggcggtctt aacggacaga
     2581 aacggctctg tgggcgctgc cccgccgttt cgtcctaacc acccaacact ccatagtata
     2641 gttagttttg tgtagtggta ccttgttttc tgggaatcaa agttgccgta tcagcggttg
     2701 ccgataaccc ataactgaca aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat
     2761 tggtaaatgt aattatggct aaaccttgtt gggtaagttc ttccggcgtg atcacaggat
     2821 gttcagattt gactttgaca ctgatttttt cgtagcgaag ttttggtagg atacattcgt
     2881 agctccaacc tagaatttcg ccctcctttt gccagcgagt gacattgacg acttggtatt
     2941 ctttttcgag tgtttctttt ggtaaactga gatcggtaat ttttattggc atcacaattc
     3001 tcctttttta tacgaaagtt tatacgattt gattaaaaaa tatagatggc catctacgac
     3061 ttgtattata tacgagaact tatacgtagt caagagattt tctaaaaaaa tatatacgat
     3121 tttttatacg agtgttataa tgaaaaaaat gataaggagg aatttgaata tgtttggttt
     3181 agtacaacct aataaagtga aggtgggcca acgaatcaaa gaaataaaag acggaatgtc
     3241 tctctctttt acagaattag ggaatcgatt aggtttaaaa aagccgacga tcagttccta
     3301 cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac caattatcta gtatcagcgg
     3361 aaaacctgtc ggctggtttt attttgggca tgtggaagaa tatatccgag agtatttgtt
     3421 tctcattggt cagaaaaaaa tagtggacga ttatcctgaa atcattgaga aaataaagca
     3481 agaattttat acgggcgagt tcaaaaatcc tgcttgggag aatgagctag gctatccttt
     3541 ggaggaattt atccaagaat gttttgtaga atattcgagt gaaatcatga aggactatgt
     3601 cgtacagatt acgaaagagg tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa
     3661 agcaaaagaa gaagctgtca cgattctttc atctgggatc attgactata tcgagatgag
     3721 tggtgagatc aagtatggag agaaagatcg cattgcgaaa atggtgaaag aatcaataaa
     3781 aacctttgat gtgaaacaag acctgacatt taatgattcc tatttgattg gaaagttgat
     3841 caatattctt ggtacagatg aagatacgga gctgtttctt tcttctttat caatgatatt
     3901 tactgataag catttttcca ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc
     3961 gatgcgacca gcgttaatca aactctatcg ggagaaaaca ccagatgaat tttatgattg
     4021 gtttgagaag taaaataaga aaagtggctt agattacaag ttggtgaaaa aatttttttc
     4081 agcataacat cagtaatcta taaaggggtt gttgattata ctgtagaagt taagtactca
     4141 agagattttt tgtacgtaaa caaagcaaaa aagggtgcag tttcactaga aaatgtactc
     4201 ttttttgtga tttttcttag ttatagagtt tttttgaaac tttaaaaatg agaaaacata
     4261 ttgattttaa agagtgtaga catagcttct tttgctaaat agattaaact tactggtgag
     4321 tggtcttgaa catactttta aatcacattt tactgagttt tattggattt tataattcat
     4381 tggaaacctc gtacttaatc tgtttttatc tatcgactag aatctgtata tattccagct
     4441 atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg ttgtttaaaa tattattatc
     4501 agaatactta gatacaaaat tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg
     4561 atatggtaat ctataaacga aaatagtggt aacgtttcca aaatgcatct tcgttaaatt
     4621 tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt attgggagga gattgaattg
     4681 gaaaagacat tgggaccagg tggtgagata agggcggtac aacgggataa aaaaaatatt
     4741 tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata agtggatgta cttgttgctc
     4801 ttaccaggta tcatcatgac gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt
     4861 gcatttaaag actataatcc tatgctagga attttggaaa gtccttgggt aggactagat
     4921 cactttaggg aatttatcag ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa
     4981 attagtattt atggtttatt gttaggtttt tttccaccaa ttattttagc actgagcttg
     5041 aatcaaatta tcaataaaaa aataaaacag aaaatccagt tgattctata tgcgccgaat
     5101 tttatctcag tagttattat tgtggggatg ctgtttttgt tcctatccgc aaatggacct
     5161 attaatgggt tagtagaaaa ggttacgggg caaccaatta tgttcatgtc taatccagct
     5221 tatttcagaa cgatttatat tttatcggga atttggcaag gaatcggctg gtcatccatt
     5281 ctttacaccg caacgctggc gggagtcagt accgatttat atgaggcagc aaatatcgat
     5341 ggggcaaata ttttacaaaa gatttggcat atcgatttgc ctgcattgag gcctgtgatg
     5401 gtgatcagct tcatcttggc cgccggcggt attatgaatg taggatatga aaaagcctac
     5461 ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca tttccactta tgtatacaaa
     5521 gtcggcttgc aatcaggtga ttatgcctac tctgctgctg ttggtctgtt caatatgatt
     5581 attaatgtcg ttttattact gattgtcaac aatataacca agcggctaaa cgatggtcaa
     5641 ggcttgtaat gaaaggagaa aattatgaat agtgctttat caaaaatcga ccgtcaaatc
     5701 ttatggttga atcgagtgat tgtaactttt ttagtcgtca tcaccattgt tccgctgatt
     5761 tatgtactgg tagcttcttt tatggaccca gctactttga tcaataaagg tataagcttc
     5821 aatccgaaag attggacaat acagggatat caacgggtat ttgcagatga ttccatttta
     5881 cgcggttttg taaattcgtt gttttactct tttagcttca gcttattgac tgtatttatt
     5941 acgatgatca ctgcgtatcc tttgtctcga cctaacttgg cggggaaaaa gattattatg
     6001 actttttttg tcattacaat gttcgtgggt ggtggcttga tacctaccta tttattggta
     6061 aagaacttgg gcatgttaga tagtgtatgg gcgattatcg taccaggtgc tataaatgtg
     6121 tggaatatta tcttagcccg tacctatttt agtgctttgc caaaagaact ttctgaagct
     6181 gctactatcg atggcgccaa tgacttgcaa atactgttca aagtcatgct tccattagcg
     6241 aaaccaatta tgttcgtatt gtttttatat gcctttgttg ggcaatggaa ctcatacttt
     6301 gatgccatga tttacatcaa agatcccgac ttacagccgt tgcaactcgt attaagaaat
     6361 attttgatcc aaaaccaacc ttcacaagac atggtgggag ccaatactgc catggcagaa
     6421 atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg tcatttctag tctgccatta
     6481 atcataatgt atcctttctt ccaaaaatat tttgataaag gtgttttagt tggttctgtt
     6541 aaagggtaag tattgttcac tatttgtatg aataaaaatt ataaaggaga ttttaagatg
     6601 aaagcaaaat ggatgctgcc aatcgttttt acttccgtac taattttggg ggcttgtgga
     6661 ggctcaaaag aaaagagtaa atcaagccct gattatgaac tagaaaatgt ctcttttcca
     6721 ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg cccctttggc tcccaatgat
     6781 cctaatgaca aattgatttt ccaacgatta gaagaagaga ccaatctcca tattgattgg
     6841 acaaactaca gtagtgattt tgccgaaaaa agaaatttgg atatcgctag tggtgattta
     6901 ccagatgcca tcttcaacgc cgctgcaggt gactatgatt tattaaactg ggcggaaagt
     6961 ggcgttattg taccgattga agatttgatc gaagattata tgccaaatct gaagaaaatt
     7021 tttgatgaaa accccgaata ccgacaaatg tctactgcac ctgatggtca catttactct
     7081 atgccttgga ttgaagaatt aggcgaagga aaagagtcga ttcatacagt aaatgggatg
     7141 gcttggatca acaaggagtg gttggataat ttgggtcttg aaatgccgca aaccactgat
     7201 cagttgatga ctgtgttgga ggctttcaag acgcaagatc caaatggtaa tggtgaagca
     7261 gatgaaattc cttttagctt tattaacaat ggaggaaacg aagacttaaa atttttaatg
     7321 ggggcattcg gtctaggtga taatgatgac cacttagtcg ttgataacga tggtcaggta
     7381 caatttactg ctaacaaaga agggtataaa gaagccatca aatatttcaa tgaaatgaat
     7441 aataaaggtc ttattgataa agaggctttc gaacaagatt ggaatacgta tgttgccaaa
     7501 gggaaagaac ataagtatgg cgtgtacttt acttgggata aagcaaatat cacgggtgca
     7561 gatgatagtt atgacgtctt gccagtctta gcgggaccag atggaacgaa acatgttact
     7621 cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac
     7681 ttggaactta cagctaggtg gatagataaa atgtatgaac cgttacagtc tgtccaaaat
     7741 aactggggaa cctacggtga tgaagcacag gcgaatattt ttgaattaaa ggatggtatg
     7801 ttaaaacatt tgcctttaga ggggacagca ccgggggaac taagacaaaa aaccgaagct
     7861 ggaggaccat tagcagttct tgattcttat tacggcacag tcactactat gccagatgat
     7921 gcgaagtggc gtttagattt gatgcatgac acgtatttgc catatattac agaagacaat
     7981 atctatccac gtgtcttttt agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg
     8041 gatatgtggg attacatcta tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat
     8101 gaagaatggg aagaatacct tgctgaattg gaacgtgtag gtttggaaga atggattcaa
     8161 ataaaacaaa ctggctatga taattttttg aagggagcac aataagtgtt agtagaagaa
     8221 acggcgattt tggataaagc aaatcgattt attgaaatga tgcgaggaaa agttaaccct
     8281 cagtatcgac aaaactatca tttttccgca cccatcgggt ggataaatga ccccaatggg
     8341 tttatatatt acaaagggca ttaccatctc ttctatcaat actatcctta cgatagtcga
     8401 tgggggccca tgcattgggg gcatgcgcgc agtagtgatt tggtccattg ggaagatcta
     8461 ccagtagcgt tagccccaga tcaaccttat gacagcggcg ggtgtttctc aggaagtgca
     8521 attgaaagag acggaaaact atatttattt tatacaggct gtcaagaaat tgatggtatt
     8581 agccatcagc atcaatgttt ggcggtctct gaagatggta ttcattttag caaatacagt
     8641 ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg ggctaataca agaatttcgt
     8701 gatcctaaag taattgttca caacgatggt tactatatgg tagtagctac taaatctaca
     8761 cagtctactg gtagaatagt gatgtttcaa tcgtcagatt tgtatacttg gcacttttac
     8821 tctgtgctgc tagaagggac ttcagagcaa ggaataatgt gggaatgtcc tgatttattc
     8881 catttagacg gacgagatgt cttaatcatg tctccgatac aaatcaagaa gaacggactg
     8941 gaatatcata atatcagttc taccatggct tgtattggtg aggtaaactg ggaaacaggt
     9001 cagatgatag ttgataattt ccatgaaatg gattttggaa tggattttta tgcaccacaa
     9061 acaacaagag atcctaatgg tggacgggtg atgattgctt ggatgcagat gtgggatcgt
     9121 acattgccta cacatgagtt aggccatctt tgggcaggct ctatgagttt gccccgagag
     9181 ttaagagtga aaaaaaatcg attggtacaa aaacccatct caactgtata tagtcattta
     9241 gtttatcaac aaggcagtga aaatattgca gtgactgaca catcagtcgt atttcgaaac
     9301 gcgctgtctg attcttcata tttacatcta gtcgcagatt tggagaaagc tgaagttttt
     9361 acaattgaat tactgcggtc taagacggat tgtctcaaac tagcctatga cactgctaca
     9421 caggtttttg aattggatcg tcagaaacta ggaagagagc ttacaggggc ggaagaagac
     9481 cctctgaatg tacgaaaagt tgaagtacct ttgattgata atcagctcgt tcttgagatt
     9541 tttagagata cctcatcaat tgaagtcttt attaatgggt tagaagttat gacggctact
     9601 ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt
     9661 caagcttttg aaacagcgag tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt
     9721 atttaatagg ttttgaagga taatgttttt agaaaagaac agatagctag atttcccatg
     9781 gatttgctat tagtattttg aaaaaattag taatttatga caaaattcat tatactaaac
     9841 ttgtgcagaa atgtgaggga tcaactatga aagcaacaat gaaagatgtc gcaaaattag
     9901 caggtgttgg agtaggaact gtttcccggg tattgaataa cggttctgtt aaagcttcta
     9961 ctagagaaaa agttgaagca gcaatgacag agttaaacta tcaaccagat ttttatgccc
    10021 gggggttaaa gatgaagcat acgaacacgg ttgctttgat tctacccacg gtatggcatc
    10081 cattttttgg cgaatttgcc taccatgtag aaacagcatt agaaagacaa aactacaagc
    10141 tttatttgtg taactccagt ggtaatagtg aaaaagaaca agaatatatc cagatggtca
    10201 gccaaaataa agtagacggc atcattggaa ttacttattc agatatcgat gaatacattt
    10261 cgagtaatct gccttttgtt agtattgacc gttatttcac tgaagaggtg atttatgtga
    10321 ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc
    10381 agaatgtagc atatatcggt gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa
    10441 aatattttga aatcgagtgc cgtcaactgg ggatttccta taaagcgtta gatatgttag
    10501 aacctttaga ccatctctca gaacgtgtaa caaatttttt gttagagaat cccgatatcg
    10561 atgggatttt tacgatcaac gatccaatgg cattagctgt cattgatatg cttgaaaaaa
    10621 tagggaaaaa cgtaccagag gatgtccaag ttatcggatt tgatggtcaa aagatgacag
    10681 aaggagatcc ttatctagtc tcaacgattg cccaacctac aaagcaaatg gcggaagtgg
    10741 cagtggcaaa attaattgct gtcattaatg gagagacagt agaaaaacgt accgtattgc
    10801 cgattgaatt tggcgaaggt gacacaacga aacctttagt gagaaacgat tttgcttagt
    10861 gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg tgtagataaa atgttatatg
    10921 gtggaataga agccggtgga acaaagtttg tctgtgggat tggtaatgaa caattacaag
    10981 tgatagaacg gaaaagtttt cctaccacaa caccagaaga aacgatggag caagtgtttg
    11041 atttctttga taagtacaaa ggaaatatcg catcaattgg tgtaggagca tttgggccta
    11101 ttgatattca aatcgaatca agaacttacg gatatatcac caacacaccg aagttagctt
    11161 ggcaaaatta tcattttgta ggagctttgg aaaacgcctt gtcggttccc atctattgga
    11221 ctaccgatgt aaatgctgct tgttatggag aatatatggc agggtatgga aaaggtaaaa
    11281 atagtgttct gtattacacc gttggtacag gtgttggtgg tggtgctgta gtggatggga
    11341 aaatagtcgc aggttttagt catcctgaaa tgggacatat gctcttacaa cgtcataatg
    11401 aagatcaatt tgaaggaatc tgtccttttc atcatgattg tttggaaggg ttagcatcag
    11461 gacctgcgat tgaaaaacgc tttggaagaa aagcccagac tatctcattt gatcatcctt
    11521 attggacgat tgaggcagat tatcttgctc agtgtgtgta taacacaacg ttactatatg
    11581 caccggaagt aataatttta ggcgggggtg taatgaaaca gccgcaacta ctcgagttga
    11641 ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga tacgcctact ctcgaagaat
    11701 atctactaac tccaaggctt gctgacaatg cgggcttgat tggctgccta gctttagcaa
    11761 taaagaaact caatcattag aatagtattt attagaacta ttcataacat accggaagtt
    11821 taaaagggta ttctgaaact taaatagtct caattcattc ttctttcttg agaatctgag
    11881 tagagacttt tattctgttt caaattaata taattacgaa atgatattga gtacaagaaa
    11941 gttcttttta ccagatcttt taaatcgaaa aatctgatat atatatttat agtactaaaa
    12001 atctgattag ataaaaagct aattcaatag gaaaataaag gtagtgaata aaagcaaagc
    12061 ccttgttagt agttaatcta acaagggctt tggtagggaa aatggtagga aaccatctta
    12121 ttttttacga aaatcaggaa ctttagtaat tgaataatgt tgatttatag gtattcctca
    12181 tccatattat gttggctctt tattcccact ccactgttgc aggtggtttg ctggtaatat
    12241 catacacgat acggttaacg tgtgcgactt catttacgat acggacactg attttttgca
    12301 agacttccca agggatacgg gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac
    12361 ggatacctac agtgtagtca tacgtacggc catctcccat aaccccaaca gagcgaatgc
    12421 ctggtaggac ggtgaagtat tgccagatgt cgcgatctaa accggcattg gcgatttctt
    12481 cgcgcaagat agcgtctgat tcacggacga tttctaattt ttcttctgtc aattcaccaa
    12541 ggacacgaat acctaagcct ggtccaggga atggttggcg ccaaacgatg ctgtcaggca
    12601 tgcctaattg ggtacctaat tcacgtactt cgtctttgaa caatgtgttc aatggctcga
    12661 tcagcttgaa ttgcatgtct tcaggtaatc cacctacatt gtgatgtgat ttgatggttt
    12721 gggcagtttc agttcctgat tcgatcacat cggtataaag ggttccttgt gcaaggaaag
    12781 aaacgccttc ttcaccggca agtttggttg cttcatcatc gaagacatat acaaattcat
    12841 ttccaatgat tttacgtttt tcttctggat cagacacgcc agcaagtttt gataagaaac
    12901 gttctttggc atcgactttt ataatgttca agccaaattt tccgccaaga ctttccataa
    12961 cttgttctgc ttcaccttta cgcaacaata cgtgatcaac gaagatacat gttaattgat
    13021 cgccgatcgc tttttgtaaa agaacaccaa caacagagga atctactccg cctgaaaggc
    13081 ctaataaaac ttttttgtca ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga
    13141 agttatccat tgtccagtca ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca
    13201 agtcatttcc atattcggaa tggcgaactt ctgcatggaa ttggattccg tacattttgc
    13261 gttctgcatt ttggatcgat gcgatggggc aatctttgct ggtagcaacg acatcgaaat
    13321 cagtcggtgc ttgggtaact aggtcaccat gactcatcca aacggtttgt ttttcaggag
    13381 tgttttggaa aagggccgct tctgcagaag tgatttccaa ttctgctttt ccgtattcac
    13441 ggtttttggc tggtttaact tttccgccta atttataagt aatcaactgc ataccgtaac
    13501 agattcctaa aactgggatc cccaaatcaa aaatcttttc atcaatacca aaggccttct
    13561 catcataaac actgtttggt ccgccagaaa ggatgattcc tttagggttc attgccttta
    13621 cttcttctgc ggtaatgcgg tggctcatca actctgagaa aacaccgaac tcacgaatac
    13681 ggcgagtgat cagttggtta tactgactac cgtaatcaag tacgataatt tt
//
LOCUS       DAFTHM010000069        13730 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFTHM010000069 DAFTHM010000000
VERSION     DAFTHM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.069"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            39..1451
                     /locus_tag="L7C88_001965"
     CDS             39..1451
                     /locus_tag="L7C88_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBP9558777.1"
                     /translation="MSQLLIATPFHVLASENSTYKIAKERTETTEMSNSDVTAESSEL
                     LTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESST
                     ISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQS
                     QPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQL
                     AQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLT
                     KGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEV
                     KGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFH
                     YSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEIC
                     KDSSLSQSMLVDPKTLLFGD"
     gene            1800..2432
                     /locus_tag="L7C88_001966"
     CDS             1800..2432
                     /locus_tag="L7C88_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBP9558778.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTYVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            3020..4459
                     /locus_tag="L7C88_001967"
     CDS             3020..4459
                     /locus_tag="L7C88_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9558779.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4754..4972
                     /locus_tag="L7C88_001968"
                     /pseudo
     CDS             4754..4972
                     /locus_tag="L7C88_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5221..5436
                     /locus_tag="L7C88_001969"
     CDS             5221..5436
                     /locus_tag="L7C88_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558780.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5653..5909)
                     /locus_tag="L7C88_001970"
                     /pseudo
     CDS             complement(5653..5909)
                     /locus_tag="L7C88_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6096..7007)
                     /locus_tag="L7C88_001971"
     CDS             complement(6096..7007)
                     /locus_tag="L7C88_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBP9558781.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(7026..8030)
                     /locus_tag="L7C88_001972"
     CDS             complement(7026..8030)
                     /locus_tag="L7C88_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBP9558782.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(8027..10150)
                     /locus_tag="L7C88_001973"
     CDS             complement(8027..10150)
                     /locus_tag="L7C88_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBP9558783.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(10155..12602)
                     /locus_tag="L7C88_001974"
     CDS             complement(10155..12602)
                     /locus_tag="L7C88_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBP9558784.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12589..12978)
                     /locus_tag="L7C88_001975"
     CDS             complement(12589..12978)
                     /locus_tag="L7C88_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBP9558785.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(13038..13541)
                     /locus_tag="L7C88_001976"
     CDS             complement(13038..13541)
                     /locus_tag="L7C88_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBP9558786.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13554..13715)
                     /locus_tag="L7C88_001977"
     CDS             complement(13554..13715)
                     /locus_tag="L7C88_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558787.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         4221 a         2710 c         2508 g         4291 t
ORIGIN      
        1 tgaaaaaatc tttaaaactt gcatcagcag ttatattaat gtcccaactc cttatagcaa
       61 cacctttcca tgtgttggca agcgaaaatt caacatacaa aattgcaaaa gaaagaaccg
      121 agacgactga aatgagtaat tccgatgtaa cagcagagag tagtgaactt ttgacaactt
      181 catcaagtga aagtagtacg acttcaaatg ccgagtcttc aacaacttca tcaagtgaaa
      241 gtagtacgac ttcaaatgcc gagtcttcaa caacttcatc aagtgaaagt agtacgactt
      301 caaatgccga gtcttcaaca acttcgtcaa gtgaaagtag tacgatttca agtaccgaat
      361 cttcaacaac ttcaagtagt acaagtgaaa taacttcttc gaaagtgaca aaaccaaacc
      421 atatagaatc ttcaaaaaag gaagcgccaa aaacggaagg acaaacaaaa actttttcga
      481 caccacagca aatagaatca acagaatctt tccaatcaca accaatacta tctggtaatg
      541 aagaaattca ttttgacaaa aatgaatctg tagaaaattt tattatgaaa attggtgagt
      601 ctgcgagaaa aattggtcag aaatatgatt tatatgcttc tgttatgatt gcacaagcga
      661 tcttagaatc tgccagtggt caaagccagt tagctcaggc accgaattac aatttatttg
      721 ggataaaagg aacttataat ggaaactttg tcattatggt aacaaacgaa gatttgggta
      781 atggaacgct ttatacgacc caatcaaaat ttagagtgta tgaaaactat gaggaaagct
      841 ttgaagatta tgccaaatta ttaactaagg gaattagtgg aaataaagat ttttatgcag
      901 gagcattaaa agctaatagt aaaacatatc gagaagcaac taaattcctt acaggacggt
      961 atgcaacaga tacacaatac tatttgaagc taaatgaatt aattaaaacc tacgatttaa
     1021 ccaactatga taaagaagtt aaaggtccac aaatgagtaa gactggatac caagtgccta
     1081 ttcataatta ttcaataacc agtttgtttg gaaatcgtgg aaatgaattt caccgaggac
     1141 ttgatatggc agctacacag ggtgagccga ttcatgcagt taaagctggt aaggttgtta
     1201 aagcagagtt tcactactct tggggaaatt acgtggtgat acaacacgaa gatggatcaa
     1261 ccgcgttata tgctcaccag caacaatacc tagtaaaaac tggagataat gttttgcaag
     1321 gacaaataat tggctatgta ggaagtactg ggaatagtac tggcccacac cttcatttgg
     1381 aaatttgcaa agatagtagt ctttctcaga gcatgttagt tgatccgaaa accttattat
     1441 tcggagacta aaaaaggtaa tcaatctgac aaagtaacaa gaaaatggtt ggattcttag
     1501 acctttgatc aggatattga gactggaatt gatatctcga ttacgatggg tttgacaaat
     1561 aaaacaagtc cattatcgaa tatcgagtgt attattgccg tctttatgct catattttga
     1621 gcaggtttca ctagatgaaa acaatttatc tatcttgagg atttcgtgta cgtatcgttc
     1681 agtcttgtat tgtaaattag tcataaaatc agactaagaa aaattggaaa tatttttttc
     1741 tgatttatta aaagttaatt gaaattatat ggtacttctt tcttgggagg gtaggtgcag
     1801 tgaaggaaag atatggtcac cttactgttg ttgaggagat tactcataat ggatataaaa
     1861 aatatcgttg cctatgtgac tgtgggaatg aaacgattgt atatcgatca aacttactat
     1921 caggtagaac caaaagttgt ggatgtggaa attataaaaa taggcataaa tataaaaatt
     1981 tgacaaataa aacttttggt aagttagttg caatcaagcc aactaaactg cgaagtgaag
     2041 gaactgttgt ttgggaatgt caatgtctgt gtgggagaaa aaagttagta tcggcaaagc
     2101 gacttctaaa aggtgatgta aaaagctgtg gatgtttgaa atcaaaaaag catcacattg
     2161 aaaataaaaa attcggatta cttactgcaa agtatccttt ggacaataac tgttcatgga
     2221 aaacaaaatg ggtttgtcat tgtgagtgtg gcagtatgtg tgagataagt tatagtaact
     2281 tattttttgg acatactcaa agttgtggat gtttaaaaag gcaagaaaca aggacatatg
     2341 ttgaagggac agtaatagag tgtctaacgt caaaattacc gaaaaataat acaagtggtg
     2401 ttaagggagt ttatcgttct aaagagaaat agattgcgta tataacttta aaaaaaaaga
     2461 ggtactattt aggatcgtat gattctatta agagtgcagc tcaagctaga aaagatgctg
     2521 aaaataaatt gtttcaacct ttgattgaca aatatcgagg taatcattaa ttattgtgga
     2581 taataattaa cagtgatata taaacatcta taatatatta ttcatactat tgatatttag
     2641 tataatccta tggaattgaa tatcatagca atgtatttga aaagcaaatt ggaaaacaaa
     2701 taggtgcaac accataaata tgaaaaaatt gggaaaaagt agaatggaaa tttgcttacg
     2761 tctcacgaga tagctcacac tattaatctg aagaacaatg aagtcgactt ttagaaattg
     2821 ctagaagaaa gtaaagcgaa ttatcactag ttactataga gtaagttcaa ataaagcatc
     2881 tccaacttac atggttacat gaggatatca aatcgaaatt actcaagctt cctatggcta
     2941 gagtcgcgag aagttgttgg gcagtagaca taggttatat tgttcttagc tacacgatca
     3001 ttagaaagga aatcctatta tgtatagtta tcaagaagat gcaaaagtcc aaaaaaatcg
     3061 ctggtggatt ttgattgcta tatctatgtt taccttcatg tccacattgg atggcagtat
     3121 tgtcaatatt gcactaccta ccatctcaga tgatatgggc ataccaatga atcaagcgga
     3181 atgggtagtg tccgtttatc tgatgattgt ctgttcttgt ttgttgctgt ttggtaaaat
     3241 tggcgatagc cgtgggaaaa tcaaagtatt tcggattggt acgctgatct ttgtcttggg
     3301 atcgctgttg tgtgggttca atcattcgct aggtatttta ttgttcgcac gggtggtaca
     3361 agccattggt gctagtatga ctatggctac aaatgccgga atcatcacgg aagtctttcc
     3421 catacatgaa cgtggtcggg cattgggagc aataggtgcg tttgtttcat taggctcgat
     3481 tgctggacca ggtcttggcg gcttgatttt gtcccaattt tcttgggcgt acattttttg
     3541 gatcaatgta ccggtgggaa tcgtaacgat gttgattgct gaaaaattct taccaaaaga
     3601 tatcaccatg agcggccata caatcgatgg agggggcttt gctgccattg cggctacgat
     3661 tatcagcttt tttggagcaa tctttttggg gcaagaaagt ggctttttcc atccagtccc
     3721 ccttgtactg ttcgtaattt cagtgattgc ctttgtcagc tttttaaaag ttgaaaagaa
     3781 agcagcctct ccattgattt ctttcggtat ttttaagaac aagattttta ccatgagctt
     3841 gattacagcc ttgttgattt tttcttccaa cttctttgtc aatgtagtga ttccttttta
     3901 tctgcaaaat gctcgcgggt tgagtcctag ctatgctggg ctgttgatga tggtctttcc
     3961 tttgatgatg gtcgtcgggg cgcctttaag cggctacctg accgaccggg ttggcccgga
     4021 gattttggta ttagtaggct tgggcttatt gtcggtaacc caggtcatgt atatgttttt
     4081 gtcagtggac tctcctttgt ggctatacat tgtcgctact gccatcatgg gtgccggcaa
     4141 tgccttgttc cagtccccca ataatacgat ggttatgagc tcggtcacta tcgaaaactt
     4201 gggactggca ggctcgatga attcctttgc ccgaaatttg gggatggtca gcgggatttc
     4261 gctttctacg acggtcttat atcaagcgat gtctgctaag atgggccagc aagtaactaa
     4321 ctatatcgca aatcggccgg atgtcttttt atatggaatg aagattacct ttttaggcag
     4381 ctttgttttg tgttttgttg cctttttcct gactatctgg cgtatcaaaa aacaaggagg
     4441 tattcagaaa aatgtctgaa aaaaccactg ttgaagaatt tttggaggcc tgcgtatggg
     4501 tgagtgggat ttccatggat gatggaagat gaagtgaact tctaaaagcc gaaaaactca
     4561 agtattatct tcaaaatact agtgctcaat gagatgcttg atttgatcac aagaagactg
     4621 cgaaagccgc tggcaaccgc aagctaggta tcccaccgat ggactacgtt ttagaggcta
     4681 ctggttatga atacggagcc aacgctctca tctgcataag aatacatcac ccagattatg
     4741 taaagatttt cgatacttct gtcaaaaaat cattaagata gataaatgat ttccgtctag
     4801 tcaaattggt tcagaatgta gacacacaga tggtaagaag tcactcacaa ttcgagaatg
     4861 gacttgtcct atttgccgta tacatcataa tcgaaacgtc aacgatagta tcaatatttt
     4921 gaccaagggc tatgaataca agcattgcct tagaaaacat caagaacctt aggaacaacg
     4981 gggatagctt ggttaataag agataccgct gtttaggctt gcaagtatac tcttttatca
     5041 agaattccgt ggctttagtc atgagaggct taatactatg aaaattttct ttagcatttt
     5101 tgatttaggt tccttttcta attataataa gatgaccact acagtaacct actgaaatat
     5161 ataaacagcc actgtagtac cattttcaaa gtagtctatg agaggagaat cttcattctt
     5221 atgaacgctg gaattgcgga tatgaattta ataaaaaaaa cccttaatga ttttacttcc
     5281 aattcaatat caaaaggtac tggtatcaat ttaagcacaa taaaaaagct gaaaagtggt
     5341 gaaagatcag tggaaaagct gaatctttta gatgctataa aaataacgga atttgctatg
     5401 aaaaatggaa aagctgagat tgaaatatgg agataattat cgtctagtga attacttgcc
     5461 acttagctga atttaacgat ccttggtgct tgaaggggga gattcttggg aatagagcat
     5521 acttgcaagc ctatgtcttt actaacaacg atatctctta ttaaccaagc tatccccgta
     5581 gttctaaggc ttttactttt atctaagcaa taatcgtatt caaaggaaat ttttgaccct
     5641 tagaaagtct cattttatca gacgtgagct taggcattgc tgaattttgt taattcggtt
     5701 ttaggttgtg ctttgagcat aatatgaaag tattctttat cacgatttca ttcatctaag
     5761 gtaatgtgat gtgattctga aattctttca aaggcagttt ttgcataagc tgacattaca
     5821 tcatcaatga catgtttaca atgtttcact actaaaataa gggggtaacc aagaagaaaa
     5881 actgaatgat tatttgtatc taattccatg gtatatcaac catttcctat atagactgat
     5941 tatgacatgg attaaaataa aaaggcacta tgtcttaatt gtcggttttc gagttaccga
     6001 atggcattca tcacccacct atagaggatg ggcgacttct gcctgaaata agttacacta
     6061 cttataactt ctaataaaat tagattgagt cattattatt taacatcaac gattttccag
     6121 tttccatttt tttgtaatac taatttgtac tgaaagtagc tagtggtttt tgatacatta
     6181 tcaaggtatt ttatctttgt actcactaga aaattttttc cgttttgtag ataaactgga
     6241 ttctctaact ccgaaaactt taagtcaata ttgattggtc gcatcgcacc attttcaaca
     6301 taatactcca attctttttc agaagctgat ggataaagtt taaaaaatgt ttctaaaaaa
     6361 tcggtgattt cttccgttgt tttggcatca atttctgaat cgttttctac ttgttttgct
     6421 tcatattttg ccttgtctgg ctttccaatc attgttggca aactagttac taaatgattc
     6481 ctgttttcat cttcaaagat tgtcactcga tatgcagaag aaattgattg cgtctttttt
     6541 ccctctgtaa tatgttgctc cactaaaaat gaaacgacaa attcttccga gtgtttttca
     6601 acatctagaa tttttacaga ttgaacttcg gaactcgtgg gaatatctgc tcgaaccata
     6661 tcttggatta aagcgagacc gttttctgta aggtactgtt cgagattact cattctcttt
     6721 tcaattgctt ctttgttatt tttccatgaa aaatattctt tcgcaaaatc ctctgtaaaa
     6781 ctttcaacgc cagaagtatt cactaccttc tcttttataa ccactttttc atgagttgta
     6841 tgttgatcaa tggcggtgaa atttttataa acgccaaaag caagactaca agacaataaa
     6901 agccaaaggg caagcaccat ttttcgatgc ttacccacgg atacaactcg ttcttttttc
     6961 ttttttgggc tcttttcctt ttgattccgt tcaattttta tcttcattct ttttcctctt
     7021 ttctcttatt tgtatcggcc agctccgata agatgctgcc gccaatagtt ttccgttaga
     7081 ttcgtccacc ccactggatc tcctgcatga aacatgcgat tctcccctgc gtaaatgccc
     7141 acatgggtca cataagtacc ggcatcatag gttgaatgaa agaaaactaa atcacctggt
     7201 ttggcatctt ttagatcaat atgagtcatg gcatcatatt gatcctgagc cacccgagga
     7261 agtttcaggt caactttggc ataacaccat tgggtcaagc cactacaatc aaaccccgtt
     7321 tctggacttg agccaccaaa cacataggcc gttccttcat acttaaatgc ctcatcaaaa
     7381 atttcttgga ctattttgtc atcaaactga gttgtagtta ggtattgctt cactaataaa
     7441 cagtaaaaca tattgccata attataccgc cacccaccat tttccttaat cgcgattggg
     7501 ttggggtaat cgactttttg accacctgat ttttcctttg aaaaagattc agctaaagca
     7561 aaactatgct tcttcccgtt tttcccgaca tgatctagat acccgccacc atagttatag
     7621 gcctgaataa tactatcttg atcacaccct agttctttgg aacgcttaac caaagacgca
     7681 aaatagagac agccttgttt gatggatgcc tcggtactta atgaattagg tggtaatccg
     7741 gctgactcag aactttgcat aacgtcttcc attgtgccac cagattccac ttgaataatc
     7801 gccaaaagaa ttggaatata ctctgttata tccgattctt tggcatactt ttccaccatt
     7861 gcacggtgtt tcaatacttc ttctgagaca ctagttccgc caggagaagt gccagaacta
     7921 ccatttccct cactgtcttc accaaacaac aaacccacac acatcaaaat acccataaaa
     7981 gagatggtca gaaaagttaa tgaaataaca cccactttct tcaagttcat tttttctcac
     8041 ctgaccttga ttttggacga tggttcattc ttttttgtac tttttgattg gtctgctttg
     8101 gcagagtgga cctctgtttc acttgttgga aagaattttt cttacttgct gattggcttt
     8161 tcccttttga aatgatttct tgactagtta gttttcgttt gatttcggga ttcagatttg
     8221 ctctcacaat ccgctttggt gcttcttttt tcagcatcat atctttctga ggttgagctg
     8281 ctttatctat tggaatattc gcccttcttt ttccctgacg atttgttgct tcactcagta
     8341 tcttgcgttt ttcgtccatt ttcgcatttc ttcgttgtcg ttgtttttct cgcaaatcca
     8401 ctcgatccgc tttttcttgg aacagtccgc gcttgaattc ttctggtgct tttttcgact
     8461 tttcgattcc tttatggaga ttgtatttca aattcgttgg cgtattcctt acctgatcct
     8521 ttacttgttt agtcttatct ttcaccaaag cttgggtatc caaaactttg ccgatttttc
     8581 tcccagccaa attcattcgg gattgtttct tattatttga aactggattc tccttagtta
     8641 agtcagatag tatttcgtga tcgttcggta atcgtgaatt ctttcgtaga gaagaaccgg
     8701 atggcttaaa tttggatttt gattgttcct ttgccaactt atttccgact gctgcaccac
     8761 caccaaaagc caaagctcgt cccacatttc gattgagttg ccgcaatttt cgattcatta
     8821 acatttgcgg ttttcgcatg acgcgtcttc ccattgactg gctatcatta ctctggaggt
     8881 tgaacatact cataatgtcg cccaatttga aatagatacc ggcaaaggtc acaatttgca
     8941 gaaaagcaac catgaaaaat ggataggttg ccgaaatatt gaaaaacatc gtggagatgc
     9001 taaatgcagt cgtaatcacc aaagtaacac ccgctcgcat cataatcgta ttgaataaac
     9061 gaataatcgc cttctttcct aaactttcat aagtcggcaa catggacaat aagaaactaa
     9121 ttggcagaaa catcgcaaag ataatgaaga gaatttgcga gaacaacata atccctgtta
     9181 gaagaaaaac aaagaaggaa atgccaatat tgaacaatac caaaaagacc acggtcccta
     9241 aacggttcat ggtcttggta atactgagat tcgcattgtc attgtcttca atctctgcct
     9301 tgaccgcttc ttcccgatct ttgcctttgt tttcatctgg actcacagat agaatcttgt
     9361 tgacccggtc ttcaccaatt tcttctatgt tggaatcatc aaattgcagt agtaaccaag
     9421 gttgttggac ttgaatcgaa aacaaactat cccgaatcaa atccacacta tcttttcctt
     9481 ggctttctga attgggtaca acgatctcgg ttccaagggt aagggccgct tcactaacat
     9541 ctgagctaaa gtcattgatt tttgtgatat aggtaggcgc ataagcaatg aacgaacccg
     9601 atagtagaaa aatcatcaca aaattaatca cggctcgaac tgctttcgtg gtttctcgtt
     9661 ttaataatcc ggtatacgcc acatacaccc ccagagctaa aatcatcaat aatagaaacc
     9721 caaaataaaa tccggaggtc tggagtccat tttcagtaat accagccaat gtttggatat
     9781 tctttccaat actttcagcc gtatccgaaa tgaaatctaa tttgtaagcc tcttgaacca
     9841 cataacccgt ggcgttcgac aaatacaaac tcaccgtcca aatgaaatta gtaatggcat
     9901 aaagaccata catcacgctt ttccctaagc catcacccca attccaaggc aaccaatccc
     9961 aagagctatc cacaaagaaa tctagttgat agttgttcag tgaatatttg gaatatagat
    10021 ttcctgcttc aactgtatca tcaactagcc ctgtcgcctc ggctaccgta ccaactaaac
    10081 tcaatagaac tatcagagtg agtatgctaa taaaaacgat tcccacaatc cgaaaaagtt
    10141 tctttttcat cccctcactc cattctctct tgaacaggtg gacgggtatc aaaggcatgg
    10201 aagagttctt caaagactgg atgtacctga accacgccta cccgaccata caaatcctgc
    10261 atcaagcatt ggccattttc caaatctcgt aggcgttttt gattgctttc atcttctcga
    10321 tccaagccaa agaattccaa ggttttcttg atttcatgaa tatcggtact gcgaaacgca
    10381 aacttcaacc cgatattatt cttcaagcgt tcatccagta aatcatcact attttgcgtg
    10441 acaaagtaaa ccccggcatt catagcccgc ccagcacgaa cgagcttatt cgataatgtt
    10501 ttcccttgcg ctacttgaag aaaactccac gcctcatcta agtctacaat tttgaagatt
    10561 tctcgattac tatggataaa gtccaaggca aaagtggaaa tgacgattag catggaaaca
    10621 ctaagcaatt ccatggtggt atattcttca aaagtggttt ctgcatctgg taaaaccaaa
    10681 tccgctactt gaatgatatt taactgccta tctaaactaa tcgactgggt aatcgaacca
    10741 tctgagaaaa gcaaatgggc aaaatcataa tcggtaaagg actcgatgtg atccgcgata
    10801 ttttccgcaa ctggtgagcc ttcttttcga agctcattaa ttacttgtaa taatccccgt
    10861 tgattgcttt gggtaaccgt ccgaatggcc ttacgcaaca ctggaaactt ctccccatct
    10921 cgactagaaa ttcctgttaa aaaggtcaga atatcaattg ctagactttc agaatccttc
    10981 tttttctcca taatcacata aggatcaagt aatccttgat tttttggctt actagttaag
    11041 ttgagaatat tgatttcatc cgcaatttct ggcaaggttt ctttccagcc accccgttcc
    11101 ccttttggat cgacaatcac agcttgtcca ccaaaaagga cggcgtaata aactaagaga
    11161 ttgttactaa aggactttcc gccaccgagt gaaccgagga atgccgctgc tagcgcattg
    11221 gtaactgaat ccttgacccc ttgtgaggcc aatgccggtt tcaggtaaac attgcgcccc
    11281 gtatctacgt tataaccaaa gtaaatgcct tccaactccc ctaacatctg agtggcgcca
    11341 aaaccaagtc cggcgagaaa atcagacgta acatactgga tataatcatt catgtatcgc
    11401 ttactagaag gtaagaattc ttcatgtagc cccatcatat cgccaaaagg ccggactagt
    11461 tttacattgg tatcatcata aaaatctagc acttcatcac accggcgctt tagttcatct
    11521 actgattcgg cacttactcg aaccacatag ctcagtttgt acatggattc tttggactga
    11581 tccaaggtag tttccaattc atctacggaa tccaatgcat ctaagacatt ggaatttgtt
    11641 tcattgtcag attgataggc atggttgtcc aagtctttta attccttttt cttattgcga
    11701 acggtagcaa gtgccttttt gttcgtcaca atctccacat tcatactagt gtcaattggg
    11761 aatgtaaatt gttgttgctg gtaatagaaa agttctgagg agggaaactc catttccccc
    11821 acaattgtat taattgttaa gtacgctaca tatgattcat gattctcatg ttccatgcat
    11881 aagtaccggg gcttttcttc aatcaaacaa cgactgggac gtaataagtc gtaacgtttc
    11941 accaaagttt ccgacttcag ctttttcttt ggtagctgaa attcatattc ttcaaatggt
    12001 gtaccctttt cgccatagat atgttcaatc aaatacatca gatcactcgg tgtgactcgt
    12061 ctgactttaa atcttcgagc caatttactt tccattagtt tttcaagctt ggtatatcgg
    12121 cgaatttctt cattggataa ggaaacaaaa tcgcccatca aatgatgatt cactccatag
    12181 acaaattctt gaaagccgga gaagaaagat ttcttgagat tctttagatt gacctcttca
    12241 tctgtcgcaa tcagtttgaa gccaataaaa aagcgataat caatctgact atcgccaatc
    12301 atggatacta atgcctctgt ctgtaaatca attcgttgtt tcgctacttc tgttaatcgc
    12361 ccggtaattt ccttttttga tcgttcttgc gtggcacgaa tactactttc tgtggcaatt
    12421 tgtaaggcat gaatcttgcc ttcacgattt tgcgcaatca attgacgaaa gttatcgtgg
    12481 acttgatatt tctgttcagg tgacaaaaag gagtaattgt aaggtattaa ctcatagtag
    12541 gcaaaacatt ctccctcttg attaaagaca agattatttt caatatactt aatcgggtac
    12601 atagttcaca ctccttacca gagtaatggg ttcgtcccat cgtttcttct gttctttgac
    12661 tttctttcct gcgaaagtga ccttaaatcg taagtgatag ctaataaaag atcgtaaaaa
    12721 tcccaatggt ttcttaccgt caaacgtttt ttgcgacatg aaccaagtaa ctgccaccgg
    12781 tatacctaag tattttaaaa aggccccctc tatcatagat agtggaggca catgggcaaa
    12841 tacgatgaca aacagcaagg ataaaacaaa ccaagccatc tggttaaaag tcacaggaaa
    12901 aggcagttga aagtcattaa ttgcataaat gaccttttca actgcccaaa tactggtgta
    12961 gctttttatt ttcttcatca aatcattcct ttaaaaagaa ggatagttta gaaatcaact
    13021 acccttcaat aattttgtta atatggatac tcaaaaacac ctcgactcgt taccaaataa
    13081 ttgcctccaa tctccaagtc tctaccacac gcatcaaaat caatatacgt cttcaagtgt
    13141 tctggtactt ctccaaaatc accagcttct acaatcaaga aatatgctac atcactcata
    13201 tcatcgcaat ctggataata gataatatca tccacatgct ctaccatctc ctcaaaagaa
    13261 ttgaagaaag catgttgaat ctcagaagca acttcaccaa ctggcgttcc ttcaagttcc
    13321 tccgctaagc cacacaaccg attaatttcc tcaattggcg tatactcatc aatctcaaag
    13381 ggaagttcat aatcatgaat tgcatattcc tcgtattcgt catttaaccc aattcgttct
    13441 ttcacttcat caaaatcgac aggtggggta aaccacgccc ccaccaattc accttcgtta
    13501 tatttcccga ggttcgcaat ataaacacgc atctgttcca tcgtgcttcc cccttacgca
    13561 ccgacaattc ggttaaacaa actgagtaag acatccttca ccccagaagc attaaagacc
    13621 aatccgaccg caatcaaagc aatcaccaaa aagccaatca gtttggaaaa ctcccgctta
    13681 aatcctaaaa acaaaccaat gaccacaatt gccagtaaga ctaaggattg
//
LOCUS       DAFTHM010000070        13691 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFTHM010000070 DAFTHM010000000
VERSION     DAFTHM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.070"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(407..766)
                     /locus_tag="L7C88_001978"
     CDS             complement(407..766)
                     /locus_tag="L7C88_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBP9558788.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(796..1137)
                     /locus_tag="L7C88_001979"
     CDS             complement(796..1137)
                     /locus_tag="L7C88_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558789.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(1134..1808)
                     /locus_tag="L7C88_001980"
     CDS             complement(1134..1808)
                     /locus_tag="L7C88_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBP9558790.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(2984..4282)
                     /gene="asnS"
                     /locus_tag="L7C88_001981"
     CDS             complement(2984..4282)
                     /gene="asnS"
                     /locus_tag="L7C88_001981"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBP9558791.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(4322..5512)
                     /locus_tag="L7C88_001982"
     CDS             complement(4322..5512)
                     /locus_tag="L7C88_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBP9558792.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(5533..6060)
                     /locus_tag="L7C88_001983"
     CDS             complement(5533..6060)
                     /locus_tag="L7C88_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBP9558793.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(6107..8896)
                     /locus_tag="L7C88_001984"
     CDS             complement(6107..8896)
                     /locus_tag="L7C88_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBP9558794.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(9043..9243)
                     /locus_tag="L7C88_001985"
     CDS             complement(9043..9243)
                     /locus_tag="L7C88_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBP9558795.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(9696..10016)
                     /locus_tag="L7C88_001986"
     CDS             complement(9696..10016)
                     /locus_tag="L7C88_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558796.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(10519..11637)
                     /locus_tag="L7C88_001987"
     CDS             complement(10519..11637)
                     /locus_tag="L7C88_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558797.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            12108..13415
                     /locus_tag="L7C88_001988"
     CDS             12108..13415
                     /locus_tag="L7C88_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBP9558798.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            13536..>13691
                     /locus_tag="L7C88_001989"
     CDS             13536..>13691
                     /locus_tag="L7C88_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558799.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLE"
BASE COUNT         3882 a         2888 c         2438 g         4483 t
ORIGIN      
        1 ttcttccata cagatgtttt ggcttattct ttctttttct cttcgatcat tgcccctgct
       61 cttatccaac ccgcacttgc cttcttgatc ttgacaggat agcaactaag tttgaagcct
      121 gttgctggca atttgtctaa attcattaat ttttcgatag gacaatatct tttttcaatc
      181 cctgcaaaat gtccttccca gatattcgaa gctccactac gctttcaaaa atatagaaag
      241 agttctttaa tgaaaattat ttcaactttc cataaacagt aatcccatat aaataaaaga
      301 cgtaaaagtc acatgggaga acttatacag gaaaacacat agagtcaggt gaaatacatg
      361 tatcccacct gactctatgc gttttctaac ctttattatt ctctttttat acaatttctg
      421 caccgaatgg catcaacgcc aatcgagcaa gtttgaaaga ttgcttggca aaaggtatcc
      481 ctatgatcgt gatacataga aggatgccgc tgacgacatg tgcgagagca attggtaggc
      541 ctgaaacgat cagccagatg atattaacga tcaatgacat gccagactgg tgataaatta
      601 cttctttgcc aaaaggcgca aaagaaaggg aggcgatctt aaaacattgc ataccgattg
      661 ggatacctat gatcgtgata caccaaagta tccccgctgc taaccagcta agaccaccga
      721 ttagtccgcc gaatataaac cagatgacat ttcctaaaca actcattgta tttctccttc
      781 tattactgtt tttgattaaa actgggcaaa aattgatttt attcttcttt ttttagcttc
      841 cagcatcaag tattctgcaa attttttttg gatttcttcc gtattttctt ttgttactaa
      901 tgtgtgttgg attagttttc ctgatggtcg ctgatccacc cgttcttctg actgttgcac
      961 gtccgcttgc gcaaatccga taatccgttt ttcttttgtt acagcaacga gcaatagttt
     1021 attcttatca tttaggtcag ctgccgtttt tgcttttacg aatgattctg gatgatcagt
     1081 aatcagctga ttgatttgag gtaaatcttc ttttactgcc caccgtattt ccatcatttc
     1141 tcacttttct ttcgctcatt tttatctcca ctaaaaaaat cgactgcggc aattgcatct
     1201 atccagcttt gtgcaatgat ctcatgtccg ccaatcgttg ggtggacccc atcttctctt
     1261 gtatatttcg aaaaaccata agcaatccct aaagcattga atatgccatc taaaggaacc
     1321 agcaatgcgc catattcctt agcaagttta cgaacaattt ggattttagg gtctaagtct
     1381 ttacgccagc catgacggtc gtcggttata ggaagtacaa acggctccat caagatgatg
     1441 ttgcagattt ccgctgtttg aagttcattt agtaattttc gataaacgga ttcaaattgc
     1501 tgcgcagatt tctcagttcc gaatatagcc tgatcgctag tattatgcca ggtatcattg
     1561 attccgatca aaatcgatac atagtcaggt tgtaaagcta aacaatcttc ttgccagcgt
     1621 acttgcagat ctgcaatttt gtctcctcct atcccacggt tcatgcattc aaatttcatc
     1681 gttggatatt gggagattag ttttccggca atcaaaagtg gataaccttt acctagatca
     1741 gttgcttctg ctcggtctct tcctgcgtct gtaatgctgt caccgataaa taatatacgt
     1801 tttttcattt gtcaaaaact cctttttgaa taaaacgatg attttcttcc ttatattatc
     1861 ccataagccc tatcaagacg aaagagaaaa tatatgtata aaaaatgaca ccagcctagt
     1921 cccttcaatc aattgaatga acgctcatca agtgtctagt tttttatact ttttttctta
     1981 acgtgccgga ttccccttga ttccttcgtt gtttggtcca gagaaatcga tcacacctaa
     2041 gcttccgtca atcagaccac tgatgacgcc atcagaacat atatttatag gctcatctaa
     2101 gacttccagt aaatgttctt ttactaatat ctcttctaga ttgcttggga tagattggtc
     2161 ataactttat ctggtccgat gatttcaagg atgaattaaa cttacatatg gatcattgca
     2221 tgctgaaaat acggacctac tccatcttcg aatgttacta ttagtttgtt ttcaggtact
     2281 agatgctgct ttatttcaac agcagaagca tcatcaaatc agatttccat ttgaataacc
     2341 ttctttgtat atgtttgatt gattgcgatt tcgttataga accttgtgaa tcaaatagca
     2401 atttcttttg ctttcttctc ttgtctgctg gaaacttcct ttatcccgta ttttaaaaaa
     2461 agaactgcga gagttcgcag ttcttttttt taaataaacg ttgctctccg gccaactcct
     2521 cggtcacaag tcacaatagt catcaaacat gaaaaactgt tttttgaaat tactccttgt
     2581 gactcggagc tgaacggcag gcgcacaacc tcttgatata aacggtgttc aatcagctga
     2641 ccctcgatat tagctaaaaa aacggtaaaa tatgagaagc tatttttccg ttttgtttct
     2701 ctaatactca ggtcaaggca ctgatttcac aacctcttcc ttaaacggtg ttcaaaagcc
     2761 agtttctcgg tattaagcca aatttatgca aaaatgtgga aagccatttc cacaaaattt
     2821 ttcttaatac tcgaaactaa acagcttttt cacaacctct ccactaaacg gtattcaaaa
     2881 gcttacatct gcggtaataa gtcccgccaa ttcaaaaaca tgaacagctg tttttgcttg
     2941 gctgttctaa ttacttgatg cagaacagct ttttcatcac ctcttatgga taaattcggt
     3001 tcaacaaacg tgggaatgga atagcttcac gtacatggtc gataccagca atccaagtga
     3061 ctgttcgttc aaggcctaga ccaaaaccag agtgcggaac agaaccgtat ttacgtagat
     3121 caagatacca tgaatattct ttttcatcca aaccgtgatt acggatttgt tctagcaaga
     3181 aatcatagtc tgttgcccgt tcgcttccgc caataatttc accgtaacct tctggtgcga
     3241 tcatatctgc acaaattacc acgtcttctc ttgttggatg tggtttcatg tagaatggct
     3301 tgatggcttt tggatagttt aggataaaga caggctgttc gaatgaattc gcaatgaacg
     3361 tttcatgagg tgaaccaaag tcttcgcccc attcgatgtc atcaaatcca tttttcttca
     3421 gtaattcgat tgcatcatcg taagtaatac gagggaatgg caattttgta taagttttta
     3481 agacttcttt gtctcgtcct agtacatcta atgcatattc gcaatgatct aaaacatttt
     3541 gtactaagaa tgctacatat tgttcctgta cttctaaact ttcttcttga tgagtgaaag
     3601 ccatttctgg ttcgatcatc cagaattcga tcaaatgacg tcgtgttttt gatttttcag
     3661 cacggaaagt cggaccgaat gaaaagactt ttccgaaagc catagcagca gcttccatgt
     3721 ataattggcc actttgagat aaataagctt tttgatcaaa gtaatttgtt tcgaatagat
     3781 ccgtagtgcc ttctggtgca gaaccagtca agatcggcgg atcaattttg acaaaatgat
     3841 gttgattaaa gaattcatac gttgcacgaa tgatttcatt tctgatctgc ataatcgcat
     3901 gttgtcttga agaacgcagc cataaatgac gatgatccat caagaagtct gttccgtgtt
     3961 cttttggtgt gatcggataa tcgtggctct cgcttaccac ttccacattt gtaattccga
     4021 tttcataacc aaattttgaa cgactgtctt cacggatttc tccagttact aacacggatg
     4081 tttcttggtg tagattttta gctgtttgga aaacttcttc cgacacttcg ctttttacaa
     4141 ctacaccttg gaaaaaggct gttccgtctc ttaattgtaa aaatgcgatt tttccgcttg
     4201 atcgcttatt tgcgacccaa gcgccgattg ttactgtttc tcccacatgg tttttcgaat
     4261 cgatgatttg aatttgttcc acgtatgact ctccttttat attccttgaa tttcttcagg
     4321 attaattttg acttttactc tcaataaatt gcttgattct gcgtaccgct tcttctaacg
     4381 tagcgcgatc agtggcataa ctcatgcgga cattttctgg tgccccaaag ccttcgccag
     4441 tcacaagcgc tacccctgtt tcttctaaaa gatcttctac ccattgtgtg acattttcat
     4501 acttacacat gcgtagcgtt tcttttacat taggaaaaag atagaaagct ccttgcggct
     4561 tttcaagaga aacacccggc agttctgcca caagcggata taacgtattc aggcgttctt
     4621 caaaggcgtt ccgcatttct tctactgtat cttgctcacc tttcaatgct tcaacagctg
     4681 catattgact gactgctgtc ggattgctag ttgattggga agcaacagcg atcattccat
     4741 tgatgatcac aggatttccc accgcataac caatgcgcca gcctgtcatc gcatatgttt
     4801 tagacacgcc gttgatgatg atggtctgat ttttgattgc ttctgaaatc gttgcaattg
     4861 gagtaaactc attgccatta taaactaaac ggccataaat atcatcagca actatcaaaa
     4921 tatcattttt tactgcccat tcaccgattg cctgcagttc attcttgcta taaatcattc
     4981 cagtcggatt cgatggagaa ttgatgatta cggcttttgt tttttctgaa cgtgcttgtt
     5041 ctagctgttc aacagtaact ttccagctat tggattcttc ccctttcaca aagacaggaa
     5101 gtccttctgc cagttttact tgctcaccgt aactgaccca gtaaggcaca ggaatgatga
     5161 cttcatcttg cgggtcaagg atcgtttgga aaagggtata caaagcaaat ttcgctccgt
     5221 ctgttacgac tgtttgtgaa ggttcataga caagtccata gtttttcttc agataatcaa
     5281 cgattgcctg tcgaagctct gggattcctg ctgttggtgt ataatagcta gctttcccat
     5341 tgcggattgc ttcgattgct gcttcttgga tgttttctgg tgtcgcaaaa tccggttctc
     5401 ccacagtcaa actcagcaca tctctgcctt ttgcttttaa tgccttggcc tttgccgcag
     5461 ctgccaaagt gacagacggt tctaatcgtt ttgttctttt tgataactcc atcccattca
     5521 ttcctttacc ttttaaattc ccttgattgt cttgacttca tctccagatt caaagccaat
     5581 caggtaataa ttcagtttcc catttgtttc ttttcctact acttcccaca caggctgatc
     5641 atcatacatc cctaaagcag ctttttcgat ttggatttca ggatgggccg cagcaattgt
     5701 ctgttttgct tcgttttcag tcagtccctt tgtttgatcc aatactttta ctttttcacc
     5761 agatttagga atgataacgg cgatttcttt tcctttatca tttgtacctg tcagtgaaaa
     5821 gtatgtcttc tttcgagtaa accaataaaa atgatcggtt tcctcaagat ttgcatattt
     5881 ctttgcgatt tctactgctt ctttcttcgc ctgcaccgcc ggacgactgg aacgcaagta
     5941 aaaaatcgag ctgatcacga tgaccgctaa taaaaatacg atcaagccaa gtaacacgcg
     6001 attaatcgtt ttttcctttg tctgtttttt cttcaagggt cgtcgctcct ttatcttcat
     6061 tccttttcat tatagcagat tttaattatg aaaaaagaca gctcctctaa cttccttctt
     6121 catttttctt taagaattca tggatatcct gatagatttc ctccatagct agctctttga
     6181 tcggtacttt tttcggtaat gcatggatga tccgtgcgcc atattttgca gtgactagtc
     6241 ttcgatccaa aataagcaat acgccacgat ctgtctccgt ccttatcaag cgacctaatg
     6301 cttggcgtaa cttcaaagct gctttaggta cggattcctg gtaaaaagga ttgatcccct
     6361 ctgattctaa ataagcgttc ctagctttga ccatcgggcg aagcggatta tcgaagggta
     6421 aacgtgtgac tacaacgatc tgcaaagcat ctccaggcaa atctacacct tcccaaaagc
     6481 tgtcagcgcc aaacaatacg cttttttctg acaaaatgaa gcgtttcaaa agcttctccc
     6541 ggcttccacc aaacccttga gctagtattt ctcgtccttt ttctagcata gacagatgca
     6601 ttttctgata gaccttctgc aaaacatcat gagaagtgaa taacacaagt attggccgat
     6661 cttcttgttc gatcagacct gtaagtgctg tctctaaata atcgatatat gcttgattgc
     6721 tgacttgatg gacggcaggt gcctcttttg gcacatagat ccttgcctgt ttctcataat
     6781 cataaggaga ggcaatcact ttaagaggtg ctgcttcaat gccaagcctc ttagagagat
     6841 agtgtcgatt agggccgatc ttcagcgttc ctccaatata aagaatacga tcatatcgag
     6901 gataccaaac agtcgacggc aacatagccg cttgaaaatc atggagatga aaaatcatct
     6961 gctgcgctgt gttcccagga acgaaccaat ggatcaaatg atctcgccag tcttccagcc
     7021 attgatccat cagcaagtat tgcttgtcta attgatcaaa taggctatat aaacttgcta
     7081 aatcgatccg catctggttt gtccagcttt cttggataat ctcaaaagtc agacgcattt
     7141 gtgactgtag ctgctggatc tcctgataaa aaagctgcag gtgatcaatg gctgtcccag
     7201 attccagtgg cagctgatcc aacatctctt ttgtcatcat gacttcttct ggatactgtc
     7261 cgttaggttg cttgccgctc actaaactca ttaatccttc tgccatacaa atctgtgctt
     7321 cgcatagcgc agaaagttct tctcgataaa tcgataacca gcgtaaggct tcatgttctt
     7381 tcggtaaata gctttgtatt cggtcaaaca gctgatttgg ttcttctaat tgctggattt
     7441 gtttatggaa atagttaata cttaatcgtt tgtcatttac tttttcagcg atttccggca
     7501 aatgatgtac ttcatcgatc aacaaaaatg gactagctgg aagcaatggt tcttttcgct
     7561 gtgtttcttg tactaaaaac gcatgattga caatcaaaaa attactttgc ctgattttct
     7621 tttgcaagaa acgaacaaag tcttgttcgt aaaatgactg atttcttgct aaaaatccaa
     7681 tacctctgtg cgcgatatct gcaaagaatg aatggttcaa atttgttaaa tgtaattcat
     7741 ccaaatcacc agtcttcgtt tgcgtcagcc aaactaagac cgccatttga tacaaagcat
     7801 attgtttttg ttctggcggt tccacaagtg tgcctttaaa acgctgcaaa tcaatatagt
     7861 ggcgatagct tttgataatt acaggttgta tgggctgatc tagcaattga ttcagcaatg
     7921 gaatgtcttt ttctatgatc tgctgctgca aaactagcga aacggtactg atgacagcgg
     7981 gtttttcagg tgtagccaaa taactcaatg gcagcagata accgattgtt ttacccattc
     8041 ctgtagctgc ttcgatcatc aaatcttttg attcatcttt tgtgaaatgg tcgtagaccg
     8101 cattcatcag tctgttctgt tcttttcgat acatcagtgt tttaccaaac attttttctt
     8161 ttgcttgttt ttttcttgga tatgtccgct cgccataatg gacggatgtg aatagttcca
     8221 cttctttttt ctgcaaagct agcccatcga cgatttctaa tgagggatca agtggctctg
     8281 gtttttcttt catttcttca atcacatgat aaatgaaacg actcgtatcc atacctgtgt
     8341 gtctacttaa tcgcgcaatc tgctctaacg tgatgattgg caattttctc atccgttctt
     8401 cgatcagcaa aagaagttga cctgtcactt cggcatcact atctgcctga tgaggattct
     8461 catgaataaa tccaaggctt tctgacaaat cagctaagcg aaagcttggt tccgtcggca
     8521 agaaaatttg tgcaagttct actgtatcga tgcctggtat cttcaaacta ggaagtccgc
     8581 atcgcatgag ttcatggttc aaaaaattat aatcaaaata aatattatgc gcgacaaata
     8641 tggtgtctgc caaaagattg taaatcgttt gggcgacatc ttcgaaataa ggcgcttttt
     8701 ggacgcgttg attcgtgatc cctgttaaat gctggatttg ttttgaaatc ttccgccctg
     8761 gatgaatatc gatcgaaaaa cgtgaagtga tccgacctga ttcaatcatg acgcagccaa
     8821 attggatgat ccgatcttct tttggattcg tcccagtcgt ttcgatatca acgactgcat
     8881 aagttcttgg tttcaaaata tcttcctctt ctcctgcctc taatgttctt ttgaaattat
     8941 actacaaagt gcagaaaaat actctcatcg ctttttaaag aaaatagaca aaaacgccca
     9001 gacacgcaaa tgtctgggcg tttatttttt agtataggtt aattaagctt tagtaacgtt
     9061 tgttgcttga ggtccgcgtt ggccttcttc aacatcgaaa gttactgctt ggccttcttc
     9121 taaagttttg aatccgtcgc cttggatagc tgagaaatga acgaatacat cgtttccgtt
     9181 ttctgcagtg atgaatccaa atcctttttc tgagttaaac cattttactg tacctgtttc
     9241 cataataaaa atcctccttg tgtatcaaca catattttgc aattacttga atggtgtata
     9301 tctggaagat gtttatttga aacaagctac cacagattac cgaacaaaaa ctactcctat
     9361 agtatatcat accgtttaca aaaaagctag agtttttcga ctttttttat taaaaaaagt
     9421 tttctcagcg attacataaa gtgaaaaacc gaactttttt ttaaaataaa cgacatattg
     9481 ttcagttggt gtttttttgc tctgatgttc ttttttaaac taaaaaaatt attctttctg
     9541 actacttatc ggttctgttt caacggtcga ggctggggaa gattctttag taggtctgat
     9601 gttctcatgg tatttctgat agcctatgac agttaccaga agaacaaggc aaaccaatac
     9661 gaccaacgag attagttttt cttttttgct catatctata cctcataaat aacaggatga
     9721 tgtccatcat atttctgagt atgagtaaaa gcaaaagctg cagctgtaga atgtaagaaa
     9781 tgccagcaac tttcataatc acaggtcgga cagtaccaaa agtaaccaaa tcttggctgc
     9841 aaagaccgtt cttctgtttc aggaatcgca gaatcaagat ctggtgtctg tacataaaca
     9901 tttttgtaca gacgtgtgcc tgtaatagga aaccgctgtg tttcttcagc aaaaactggc
     9961 tgacttgtta aacttaggga tagagacagc aaacaccata acagtctttt tttcataaag
    10021 acctccttat cgataagttt ttcccaatta aaatcatatc tcaagaacgc ccgttattca
    10081 cattttgttc ataaatgatg ttttttgtat cataatcgtc aaaaagaggt cgtgaccacg
    10141 tcacaacctc ttttttaaac ggtgttccag aagtagcttc ttcggaaata agccgaaatt
    10201 tcacaaaaat ttgagaaata atttttgtca atctcttctt atttcttgaa gctgaccact
    10261 tctgtcacaa cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca
    10321 ccaaacaaaa aatatgaaga gctatttttg cttgctgttc ttattacttg atgcagaaca
    10381 gctttttcac aacctctcat acacggtgtt taatcagctg accttcggta ttagctcaaa
    10441 aaacggcaaa atatgtgaaa ctatttttcc gtttgtttct ctaatactca ggtcaaaaca
    10501 ctgatttcac aacctctttt aataacgaag aatcgctgtc agactctttt catctggcgc
    10561 atctttttga tccaaaataa acacttttcc gccattaatg atcacatcat ctgctaatgc
    10621 attcaacact tgacgccgat catattctgt ttcaggatct tcaccgaaac catcagctaa
    10681 gtttgacgta gcgataaata aatgtgacac ttttccttct ttcgcagctg gaacgatatc
    10741 aactaactga tcgatgaatt tcttatctaa gagtttattg tattcttttg attcttgagc
    10801 tgcgagttca cttgacagct tcttcgcccc ttcttcgata tctctaaagg atagctgcgc
    10861 aggagaagca gaaatcgcaa cgtctgcaca ataataggga tttttagcaa tttttttgaa
    10921 catcgtctga ttttctggta gagcaaataa ataaatcggc cattgttctg gattttcgaa
    10981 agaatccttc aagtacgtat caactgcttg gtaatagttg acccaatcga tctctacttc
    11041 ttcatctttt ggatttacgc catggaaagt tactccatct cgggctccgc ctcctccatt
    11101 agaagagaag ttcaaaccgc cacctgtcag ttcagatccc aatgcagtaa cgacatcaac
    11161 cggtgcccct tctggtagag atacttcttt tacttgtttg ttgctgactt catacaattt
    11221 catggagtcg cggttcaatc ccaataaata ataagaatag ttgaactgcc catttttgat
    11281 aatagccagt aaataaggaa gatcacttac atagtattga tcgtctaccg ggatactcaa
    11341 acgatggata taggtttggt cagcagttat aatgaccgct acactcgtag ttgcactacg
    11401 ccaaaacgaa ggatctccta acaaattttc aattttttct tggaacgggg accagtcatg
    11461 ttcggaatat tttttctcaa aacgtttctt tgcttctttc gcaaaatttt tgaatttgat
    11521 ctgatctttt tccacatctt gatgggcgac atgcgtattc agcatgatcg tgacgaatgg
    11581 tcctttagcg ccttctgaag tcaattgtga caataattct ttatcctttt ttgccataaa
    11641 cgtacccctc ctaaaaaaat cattcctttg tttctatcta aagtctacca caacactatt
    11701 tttccataca ataaaacgta tctaaaaaaa taaaacggtt tctacggttt taaatttagc
    11761 tattttttta agttatcttc ataatttcct caattattta gccccagtct tcaactattc
    11821 ttcatgaaat gctgataaac taagaaaaag aataaaagag gtggatctta tgcatttgat
    11881 tatgattttc agtttattaa gtattatcag tttatttgct ttcagcgctt cccgcttatt
    11941 agatgcggaa acacagccta ttcctgtaaa agtacgtaaa aacgaccgct aaccttccat
    12001 aacgtgcgtt cttatcctaa agttttttca gaaacattga aactctctcc cctctctgat
    12061 aaaattttaa tttgtagcga aacaaattaa ttacaaggag atcggatatg tccataaaaa
    12121 aaacacgtct agtcctatta ttggctagtc tcattctttg ccttgcttct tttctaccag
    12181 ctgttgctgt gcaagctgaa gatactttca aagtaaatgc aaaagcagcc tttgctgtag
    12241 atgcgcaaag cggtaagatt ctttatgatc aagatggaga aaaaaccatg gggatcgctt
    12301 caatcacaaa aatcatcggt ctttacatcg tccttgatca agtaaaagaa gggaaactat
    12361 catgggatga taaagtttca atttcagatt atgcagaaaa tttgagtgtc accccagatt
    12421 tatcaaatgt tcctttgcat aaagaaaaca cctacaccgt taaagaatta ttcgactctg
    12481 caatcatcca gtcagccaac gcttcaatgg ttgccttggc agaaaaaatc tctggcagcg
    12541 aagcaaaatt cactgaacga atgaaagaac aattgaaaga ttggggtatc aaagatgcaa
    12601 cgatcgttaa tgcatcagga ctgaataact cttatcttgg cgaaaaccga ccagaaggta
    12661 ctggagaaaa cgacgaaaat caaatgtctg ctcaagatgt ggctatcgtt gcccgtcatt
    12721 tgatcttgga ttttccagaa atactggatg tatctagcac tacgacacaa atgtttggcg
    12781 aaaacacgca atcaccagta gaaatggtca actggaactg gatgctccca ggattcgtga
    12841 attataaaga aggcgtggac ggattaaaaa ctggtacgac tgaacttgca ggagcctgtt
    12901 tcgtcggtac gatcactaaa aacgatcaac gaatcatcac tgtcgtattg aatgcagacg
    12961 gccatgcgga aaacccaagt gcccgtttca atgaaacagc tcgcttaatg gattattgct
    13021 acgacaattg gtcagaaaaa gagcttggaa aagccaatgc aagtatccct agtctaaaaa
    13081 ccattgatgt aaaagacgga aaagaatcaa cagtgcccgt tgtgcttaaa agtcctgtaa
    13141 aagtatgggt acggaacgat atggatactg gaaaattaac aatcacacca actcttgaca
    13201 aaaaacaagt cactgacaat gagatccaag cacctatgga taaaggaaca aaaatcggta
    13261 ccgcaacgat caccttggca gaagataaat taggttatct tgaagacaac aacgcgccat
    13321 ccacagaaat catcacggat aaaaccgtag aaaaagcaaa tattttcgtt attggctggc
    13381 gacgcgtcgc agaatttttc ggtaacttgt tttaattgaa caaaaagaaa aaagcatctt
    13441 tccatgtgga agatgttttt ttgctttttc tagtttaaat aacagctttt ttcatctatt
    13501 ttcgttatac tgtataagaa aaaggagttg aatttatgaa tctaaccaga gatctgattt
    13561 ttttggttct ctatcttatt ggggtattct ccatcgttta ttggcgaaaa cagaaaaagg
    13621 atccttcctt gttcttttac agcagtacat ggacgtttgc ggtaatcttg acttattttg
    13681 tcgtgttgga a
//
LOCUS       DAFTHM010000071        13604 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFTHM010000071 DAFTHM010000000
VERSION     DAFTHM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.071"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(119..1249)
                     /locus_tag="L7C88_001990"
     CDS             complement(119..1249)
                     /locus_tag="L7C88_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBP9558800.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            complement(1790..1996)
                     /locus_tag="L7C88_001991"
     CDS             complement(1790..1996)
                     /locus_tag="L7C88_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558801.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2012..2626)
                     /locus_tag="L7C88_001992"
     CDS             complement(2012..2626)
                     /locus_tag="L7C88_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBP9558802.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDKVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(2773..3456)
                     /locus_tag="L7C88_001993"
     CDS             complement(2773..3456)
                     /locus_tag="L7C88_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBP9558803.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3565..4023)
                     /locus_tag="L7C88_001994"
     CDS             complement(3565..4023)
                     /locus_tag="L7C88_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBP9558804.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4107..5870)
                     /locus_tag="L7C88_001995"
     CDS             complement(4107..5870)
                     /locus_tag="L7C88_001995"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBP9558805.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6091..7551)
                     /locus_tag="L7C88_001996"
     CDS             complement(6091..7551)
                     /locus_tag="L7C88_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558806.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQFLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(7759..8685)
                     /gene="glsA"
                     /locus_tag="L7C88_001997"
     CDS             complement(7759..8685)
                     /gene="glsA"
                     /locus_tag="L7C88_001997"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBP9558807.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8708..10135)
                     /locus_tag="L7C88_001998"
     CDS             complement(8708..10135)
                     /locus_tag="L7C88_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9558808.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10166..11380)
                     /locus_tag="L7C88_001999"
     CDS             complement(10166..11380)
                     /locus_tag="L7C88_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBP9558809.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(11721..11963)
                     /locus_tag="L7C88_002000"
     CDS             complement(11721..11963)
                     /locus_tag="L7C88_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBP9558810.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(11995..12552)
                     /locus_tag="L7C88_002001"
     CDS             complement(11995..12552)
                     /locus_tag="L7C88_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBP9558811.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(12565..12753)
                     /locus_tag="L7C88_002002"
     CDS             complement(12565..12753)
                     /locus_tag="L7C88_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBP9558812.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(12766..13332)
                     /gene="amaP"
                     /locus_tag="L7C88_002003"
     CDS             complement(12766..13332)
                     /gene="amaP"
                     /locus_tag="L7C88_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBP9558813.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4069 a         2810 c         2218 g         4507 t
ORIGIN      
        1 taatatgatt ttttgagata ctttcattgc gaattcctct ttctaaaaga acctctcgct
       61 tgaaaaataa aagattgtac tttatgataa ttcaaactga gagtttctca gtttctcttt
      121 attgtttttc aggtcgatag agcgccaact cttcggcctg tatctttgaa gaaatattca
      181 acgtgattcc gattcctaaa gaaaggatca gataacttgt tcctccgtag ctaacaaatg
      241 gcaatggcac accagtcatt ggcatcagcc ccgcgatact tcccacgttc attatcgtct
      301 gaacgaatag caaagttccg aatcctaaaa gaaacaatcc agcttgctga tttttacagc
      361 gactgcttaa acaaaagatt ctcatgcata atgagaacaa taagaaaagc acacacaatg
      421 caccgattag cccaagctct tctgtaataa tcgaaaaaat aaaatctgtt tctgtctctg
      481 gaagataccc tttttttgtg atactatttc ctaatccccg cccaaatatg ccaccattat
      541 atagtgcata aaacgaatgg gtcatttgat agcccgcacc atgactatcg ataaaagaat
      601 ctcttaaagt cgcgatcctt tcataagcat gattaaacat ctgtggaagc caacctttat
      661 ttcctaaata taataccccg cctgctgctc caatcagcaa tgcagaaaaa gtaacgatta
      721 gatagatccc ttttttaaat ggaaccgccg ctgcccaaaa tatgacccac gcaatcgaaa
      781 ggatcatcaa tgctccagca atctttggct gaaataaaat cagaaaagtt atacctactg
      841 taatcaggaa tggttttttt agatcttttg ggctactatt tccgtcacga aaaaaccagc
      901 ttaaataaaa aatcaaaaaa agatttgcca gttcagaagg ctggaattga atgccaaaca
      961 gagagatcca acgttgtgcg ccgttgacag tgacaccgaa tatccctatt cttactaata
     1021 ctaaaaagaa aatcgataag gctaaaccgt atcctgctat tttagggtga agtaaatagt
     1081 gtagtttgac tgaacgagct aagaagatca cgctccaact caaaaatatg aaaattagtt
     1141 gacgcaataa tagacttttt gtattttcat cggcttgcaa taaacgataa gaactggcac
     1201 tgtatacttc taaaagaccg atcatggaca aagtcaaata aggacccaaa atccaccaat
     1261 cgatcttttt tcaccgcatc tcctcctcac acagcaatcc acttgtcagg tgaggagcga
     1321 gtttgtctca tcaaataagt cagtcacaaa aatataaaga aaaggtcaga aaccttttcg
     1381 aacaagaatt ctgacctagc atcatctcat cgtccgagtt ttagcactat acaacgtaaa
     1441 gaaaacattc ttagctattg gaaaaagcct taatccaaca gtttctgttt tacccattgg
     1501 cgactttcga cgtttctggg caacagccta tgtttgtata ggagcctcac ctaacaaggt
     1561 tattactata ttctatttac gagttcatga tagacttttc ctaatgatta ggcaatggaa
     1621 tttgaaatga aatagtgaaa tttaacaatc tttaatattt tttagaaaaa aataacaaat
     1681 aagttgaaag aatcccgttg caaattcttt cagttgcacc aggattcttt gataattttt
     1741 tagttttatg tgttttttta tatgtttttt cacttttcgg aataaatatt tatttgttaa
     1801 agtaattaaa caatccgcta atcgtttgat ctggcatttc tatttcctta ccatctaaag
     1861 taacagtagt aacgacaaaa tggtcttgca atggcggaac ttctaagtac tgcccttgca
     1921 gaaaatcatt cactgtttca tattcttttt tcatttcttt tgaatctgtc gatggtttat
     1981 agcttatttt taacataact agtgctcctt tttattcggg acgtgcaatc gtgaaaattt
     2041 ctcctattgc tgcataatca tttcctgcca aacggcttac agcattcaat tttcttggat
     2101 cgatccttcc tgtcttatca tcatagactg tttcatttaa atgatatttc tgtacttcta
     2161 gcaaaaataa atcagctgtt actttatttt tattccgtat ctcgacatgt tcatataagg
     2221 atgtttcaaa acgaactttt gcttctgtca atgctggtac tgaaatgatt actgaatcag
     2281 ttaaagtcaa gtcagtcagg tacagttcgc tttcctcatt aggcagattg gctgctgttt
     2341 tatttacttc ttctactttg tcctcatcaa ggatatggat aacagcttct cttgtctcaa
     2401 gaatattctt tgctgtgtct tttactgcat cttgttttct ctggatcgcc aaggataaga
     2461 tgggtcgatt cgaactgacg atattgaagt aactgaaggg tgcgatattc actatatctt
     2521 ttgctgattt agtcgttact actgctactg gtctagggat gactgaacca atcagcaact
     2581 tgtaattttc acgttctgtc aattctgaag gactccgttc aaacatggtt tcgccttctt
     2641 tctataaaat tcgttaaaaa gcagatcttg aagacaaaat gaaaagtaat gcttttttca
     2701 tcttcttaga atctgcttta aactatctat caatttttct tttttgtcaa gaatctgtgc
     2761 cgtgcgtgtt ttttagttat ttgctttact tgcggcttcg acatatcttt tagtgatcaa
     2821 ttgcggacgg gtgataatag atccaactac gactgaaaaa gcacctaatt catatgcttt
     2881 ctctacttgt tcaggagagt cagtatgtcc ttccataatt actgggatat cgacttgttc
     2941 tatgatttga ttcaataaat caaaatcagg tgtctgcgtc tttcgtgaat attctgtata
     3001 gcctgctaaa gtcgtagaca aaagatcaaa accatcttct tgcgcttgaa gcgcttcctc
     3061 aaaagtcgaa atatctgcca tagctaaccg accgtgttcg tgaatcattt ggacaagttc
     3121 agcagttgtt ttttctgtcg gacgtttacg agaagttgca tccagtgcaa tgatttctgc
     3181 ttgcgtctcc aaaagttctt ccacttcttt ttctgtcgca gtaataaaca cttctgaccc
     3241 atcgtaatct cttttgataa tccctattac cggtaaatca acgattcgct tgatttcatt
     3301 gatatcttct gtcgtatttg ctcgaatacc aactgctccg ccttcttttg cagccaaagc
     3361 cattctcccc ataataaaag aactgtgtag cggctcgttt tccaaagctt gacaagaaac
     3421 gacgactccg cctttgattt gttccagtgt atccacaata tctcctccag taatgttata
     3481 taaaaataca gcttcatata aaaatgtaac ccttttctat tcaggagaca ataatgagct
     3541 atttctttca gcagaccttt cttactaaaa gaaaattact tcaaattctt cgtatacgac
     3601 cagcttctct tctgtaaatt ctatgttcaa cgcttcttta taagcatgtt taaaaaactc
     3661 agcatggact ttccgccaat aagctaatgt ccgatcccct tctccttctt tccaagcatg
     3721 ctctttcgtg acttcactaa aaggcaagat ggtcacattt atatttttga tgatacaaac
     3781 tggttcattt tttccattca ggaccacgtc taattgacca acttttggta aaggctcatt
     3841 ctcttgttta tacagatcgt aaccacttga tgtaccagtc tttatctttt ttacaactag
     3901 ttcgctcaac tcgtctgcca ttttttctgt atccccaaat gaaaagaaac ctaatttttc
     3961 tgattgataa ctaggatatt tttcttggaa ctttttgaca tattcttcta cttgctgata
     4021 cataacatcc acccctttgc tttttataat gaaaaaacca tccagatact agtataaaca
     4081 attatctgga tggtgagcat aatgaattat tgaatattca agacacgcag actatcttca
     4141 acgatttgtt ttggtgttaa atgataacgt tcataaagct gccctacagg aacgctatcc
     4201 gtgaattctt tctctgcacc aaaatttaat acgttcattg aagaatcacc ataataacga
     4261 ctgatatttt cgccaaatcc tcctgacaaa ctaccatctt ctaatgtgat gactaattcg
     4321 tgtgtttctt ttaatttatc taatgtttct acgtcatttt ctgtgatcgt tcctggattg
     4381 atcaacgttg cttcgattcc tttttttcta aaagctttta ctgtttcttt tcctaattca
     4441 agaaaaccgc ctaaagctaa aattgctact tttcctccat tatttactgt ttgataggct
     4501 ggaatactat aatcatttgc gatagctgta ccatgttcta caccatgtgt aggaattcgg
     4561 attgctacag gctgcgctgt ttgttcgaac gcccaatcta gcatagagat catatcctct
     4621 tttgttgctg gagcaagata tttgatgttc gggatacttg ataagtaagg aatgtcaaat
     4681 gttccttggt gtgttcggtc actagctgag atcgttccgc caccgactaa aataatcact
     4741 ggattctcgt tgatcgctaa atcatgtgat aattgatcat atgcccgttg caagaaagta
     4801 cttgattgga agacgactgg acgtactccc tgagaagcca aagcagaagc gaaagtgata
     4861 gagtgctgtt cagcgatccc cacgtcaaaa taatgatctg gatgtttttc ttggaatgtt
     4921 ttcagtccaa aggcgcctgg tatcgctgca ttgactgcgg caataggagc tgtacttgtt
     4981 tgcattttct tatccaaata atccatgatg atcatattaa atgtttctcc agaagttact
     5041 tgctttgcct ccccggtgga cagatcaaat ggtacatgcc aatgatattt cattttatta
     5101 tcgattgccg gctgataacc gcgacctttt tccgtatgga cgtgaagtac aatcggatga
     5161 tcaatatctt ttacttcttc aaataaacgg atcaccgttt ccagatcgtt tccattatcc
     5221 acgtaacgat aatcaaatcc cattgcttta aataggttat tgctgctttt accgttggtt
     5281 tgacgaagct cagctaagtt tttatataaa ctgccatgat tctcatcaat agacatctca
     5341 ttatcgttta ctaatacgat tagattggat tgtaaaacac caccattgtt caatccttca
     5401 aaagctaagc caccacttag ggagccgtca ccgataaatg ctaccacatt tcctgattct
     5461 ttcttcagat ctctcgcttt agctaaacct gttgctaagc tgatagatgt agatgtgtgc
     5521 cccactgtaa aatagtcatg tttactttca tgttggttgg aatatccgct cacttcacgg
     5581 taatgtcctt tttcaaaacc attttttcga ccagttaaaa gcttatgacc ataagactga
     5641 tgggaaacat cccaaacgat tttatccttt ggtgaatcaa atacataatg aaacgcaatc
     5701 gttaattcta ctacacctag attcggacca acgtgcccac ctacatcgct gtccttttgc
     5761 aagatttttt ggcgcatctc ttctgccaac tgtttcattt cctcaacaga taattttttg
     5821 acatctgcgg ggctattgat tgcatccaat acatgtaata ctgtactcat aatacattct
     5881 ctcctccgta ctatcttctt ttaatgaaaa tagatttgtt acactttatc tattctacta
     5941 cttagagttg actctaagtc aatagcattt taaaaaaatt tcagagaaag cttgttatat
     6001 aagtagatct tcgcacgaat caggactcaa ataaaaacct tctacagaca attaaaaagc
     6061 tttgtagaag gtctcctaat taaggtctca tcaagaaata tgttttttta ataggtgaag
     6121 ttcctgagca atatgataca aatggatgtt tgcacctttt aatgagattg gatagatctt
     6181 tgtcttttca gtttctaatc cattttgata gctagcagca tcgcacaaaa ccactctttt
     6241 tttcgcacat agacattcat caggcaattc ttctaatgaa cgaaataaaa taggatttat
     6301 ttcagcgatg ccttcttccg catacaaatg aaattgggtt cgataaaaaa attgtttgac
     6361 tgaactttct gaaacaacaa aaatttctat ttcctgtctc cccgcttgtt cactgttgat
     6421 caaagaaaga cttttgacga attttcgaat gaaattttca ttccatctta gttggatttg
     6481 atttttcttt ttccactctt ccaatatttc tacaattttt ccgtacagaa attgttcttt
     6541 ttctgataga agatagatcc tttccggtaa aaatacttgt ccatctgccc acaacgtacg
     6601 gacaaattgt aaaaaggatt gcttgaaaat aaaattttct gcatcgtcga tttcagcgat
     6661 actaataatc tgtaaaatca attcattcag tgataggtca ttgagaacaa aatttttata
     6721 aacaacttcg aaatcttttc ttaacagctc catgttctca ttggtataat ttctactgtt
     6781 gaacaaagaa aaaatataat agacatcttc ttcttgtaag tctagaattc ctttttgctc
     6841 ttccaatcct tgacagacta attgaaataa cggcttcgtt tctgcgcttt tcttatcttc
     6901 ttctttcagt ccaaggggaa atgcctttct tccgattgcg atctctattc ctcgtatgat
     6961 aaaggacttt tcatcttccg aatatcttct tttaaaaaaa tgagtctcta cataatcaat
     7021 caactcgtta caagcttctt ctacatacgg atttttattt tcatagcctt cccaattgac
     7081 ataacgtact aaagctagca agatgttccg cgagtcaaat tctgggataa tgatttcttt
     7141 atttttcaaa taatcatttt ctttaaaaaa atccaatacg atttttttga ttgtatatac
     7201 tttgctcaaa gaaataaatt caagatcagc cagttctgta ctcgtgaata taccattaaa
     7261 ataataactt aaaaacttta aaaaataaga ttgaccgtac agaaactgtg tgagctcaga
     7321 aagagcaata ccatgtttga atacgagttt atacttatgc ttctctctta cttgttcttt
     7381 tatacaatat tctagacact cggctagact ttctagatcg tgaaggatcg ttggtgtagt
     7441 cacccttaga gaaatagctg tttgttcgat gtctatttct tggaattcaa ataattgttc
     7501 acacagatac acttttctaa atatatttcg ctcgatgtaa ttttccagca ttcctgatac
     7561 acgcctccag tttttcttat gattttattt aatcatatct gtaaatcgta tttttgtttc
     7621 ctttttattt agaaaagccc tttcaaaaac caataaaaaa agaaactggg acaaaagtca
     7681 aacaagctca caatttcagc ctcattgtag gtagctttga gccgtttgga cttttacccc
     7741 agcctctttc aagaatggtt attcaaagat gtcagcgtct agttctttga ctacatcttt
     7801 caacaattgg ataccagctg cgctgttacc aaatggatct agtgccgggc tgaagacacc
     7861 tatgccgtaa cgatttggca cagctgccat caacccgccg cctacaccgc tttttgcagg
     7921 tacaccaaca tggacggaaa actctcctga ttcatcatac aaaccagcag ttgtcataat
     7981 tgatttgacg attgtagcac tttcttcagt aatgatttgt ttgccattcc aaggagcaat
     8041 tcctttattt gccagcacag cagctaattt tgctatgcct gtagcggtga cattgaggga
     8101 gcattgtctg aaataagcat cgagtatctc cggtacgtct ccttcgatca tttgattacc
     8161 tttcatatag taagcaagag agcgattgat atcacctgtt cttgattcag aatgatagat
     8221 ttcttcattc aatgtgatat taggatcatc acagatctct ttcataaatg acaagattcg
     8281 ctcaaatttt tcatctgcat ctttaccggc aatcaacgag gttgttgcaa tcgctcctgc
     8341 attaacaaaa ggattcattg gatgtttgcg atgattgatt tccatattca tgatagaatt
     8401 gaaggcaaaa ccggttggtt ccgtgttgat tgtttgaaag actttttcta ttccgttgtc
     8461 tttgattgct aataacaata cgggaacttt tgacatgctt tcgatggcaa agcgcacatc
     8521 ggcgtctcct ccctcaatca gttgttttgt atccaaatca taaatcgcca tacctaattg
     8581 tttgggatcc acttcagcta atgctggaat gtaatccgcc acttgtcctg tttgataata
     8641 gtggaaattt tttccaatca attgttctaa ttcttttact tccatttgaa taaccagctt
     8701 tcatttttta tttttctgca tgctggaatt tatgacggca tgcgtagatc gtaaatggaa
     8761 taactaagac gataagataa gaaacaatca gaatcgtttc ataaatccca tgctgtccag
     8821 ctgcgatact agcaggtgga acaaatgaga tacaaaaagc aaaaagtgaa gtcaaaagac
     8881 ctaaacaagc aacgattact tttacaactt ttccgcctgg aacctgatag gctctttcaa
     8941 gactgtcatc tttaaaaacc agcttcaaat agcccgcgaa aaacataaag tacaacatca
     9001 ggtagattac aacagtcaat gacatcgctg caagaaatga aagattattc cccccgccgc
     9061 ttaatgtaaa gacggctgcc cagattgttg caacgatccc atttgcgatc atcaaatgag
     9121 caggaacacc gtgtgtgttt tcttttgcaa aatattcagg aagtaatcct tcttctgctg
     9181 ctacgtgaag tgcttttgaa ggagaggtta cccaagaagc aatttctccg atgacaccta
     9241 aacaaacaag aatcgcaaga attttcgcaa tccatgcaag atttggatca atgtgtctta
     9301 ataggaattc taacgattga atcacccctg tattaagaga caaaccatgt tgaggtactg
     9361 tagtagcgac ggtcaatccg ccaaaagtat ctaaaatgat tgccagaata accaatacaa
     9421 acattgctaa tggataatcc tttttagggt tttccatttc atttgcatga ctggcagatg
     9481 tttctacgcc catatatgct aaaataaagg aaacaaaaac aaccagcgta ggcaatttcg
     9541 aaaaatcagg aatcaatgtt ttcatagaca gtatcgtttg tagtggagcg cctgaagcga
     9601 cataatggat ccctaagcca aacaagacta atgctggcaa caagatacca gctacaaaac
     9661 cgatccgagc aatcaatgaa gtgtatttgg ttccttttaa ctgtgagagt aaaatagccc
     9721 agaaaataat caataggatt gccaatttca gatatttatt gttttgtata gcaccaatac
     9781 ccgttgcata ggataatgca ccagttaaga aatacagcat ggtcaagtag ccaactgtta
     9841 tctcaaacca ttggaaaaag attgcggcaa aaccgaatcg ttttcccaat gtgcgactga
     9901 cccaagtata gacaccgcct ttttcccatc ctttcaccgt tgccatctct gctgcgcaca
     9961 atgccacagg gataaaccat agcaaaccgc ctaataacaa gaaaaatact aagctgaagc
    10021 ctgaggtcgc gaatgtggga tattcatata atgaaacgac cattgagatg gtcatagcca
    10081 aaaagccaaa gaacgttaat ttttttgcag gaattttcgt tttgctttgt tgcatgaatc
    10141 ttcctctttt ctattttaat ttgtttcaat tgagtttgtt gccaaagaag aaaaagtcca
    10201 atccttcttc ttgttcttct tttgtagtag tgatcgttgt aaagtgcatc gccgatttta
    10261 aaatcactgt tgtcagcaca taggcataca cggcagtaat gatgacacca atcacttgaa
    10321 tccctaagaa gtaccagctg cttggattcg ttagtaaatg gctgttagat gcaaagatcc
    10381 ctatcagaat cgtacctgtg aatccgccca tgccatgaac accccacaca tcaagtgcat
    10441 catcccattg tttcttttta cgaaaatcaa cagcagcatg acagacgata cccgcaatga
    10501 tcccaatcag catggcactt tttgcttcta cataaccggc acaaggcgta atggctgcca
    10561 atccagcaac ggatcctgtt agtacgtcga caaaatcaaa gccatttcct tttacttttg
    10621 caatgatcag ccaagtaatc atcgcaaatg caagagcgat gaatgttgaa ccaaatgcat
    10681 tgactgcttg ttcatctgct cgaagtgcac caccggaatt aaaaccgaac cagccaaacc
    10741 aaagcagtcc tgtaccgata gcagctgcca taagactgct atgctgactt ctttctccta
    10801 aaggaatctt tctttgacca agtgtgagga tacatgctaa agagccgaat ccagctgtcg
    10861 tgtggatgac tgctccacca gcgaaatctc taaatcccat ctgatccaaa aatccgccac
    10921 cccatatcca gtggcaaaca gggaaataaa tcagcagatt ccaaaaaata acaagtataa
    10981 tatagccttt taaattcaat ctccctgcaa aagctcctgt catcaaagga acggtaatca
    11041 cgataaacat cagttggtaa agaaagaaca ttaaaaatgg aatcgttgca ccatgaaaca
    11101 tgttggggaa gcttgtaaca tgtctcatca aaaagaaatc tgccgggttt ccaataacac
    11161 cgccgatatc ccgtccaaag gccaatccga atccaccaaa tacccacata atcgttgtta
    11221 tcccaacgga gagaaaagat tgagacatga tcgttagtat attattcttc cgtgctaatc
    11281 cgccgtaaaa aaaagctaga ccaggagtca tcaggcaaac cattgctgta cataaaatca
    11341 tgaatgctgt atctcctgta ttgataggta atgtattcat ttttttcgcc tcctttctac
    11401 gattacgagt ataaaagaag gtgtagttgt ttttttcttc tgtttttttg aattaatact
    11461 tgcatttata aaagacagac aattaataaa agcttgatgt gttgtgctct ttttcgtttt
    11521 tcacacaaat aaagacaaaa aataaacggt cttcttttta tagaaaaccg tttattttcg
    11581 tcttttttta tttttaaaga tattttttca taaggaataa agaatacttc atataaaata
    11641 tataaaaaag aaccgcagcg agtgtcgcta cggttctcaa atttgttctt catttcaaca
    11701 taagtttttc ttcaatttgc ttataattta cgtgcaaaga atgaaacgac taatactaaa
    11761 atgattgcac cgatcaatga tggaatgata gccattcctg caattgttgg tccccaagtt
    11821 cctagtaaag cttgtccaat tgctgaacct actaaaccag caatgatgtt tgcgatgatc
    11881 cccattgatg atcctttatt cgtgattgct cctgcaattg ctccaatgat accgccgacg
    11941 attaatgccc aaataaatcc cattttaaat tcctcctaac tgacttctta cttcttattg
    12001 tacacgtggt tcgttatttt ctttgacttt ttgtgcacct ttgcctacag cagattttgc
    12061 tttatctgtt tggcgtgaag caaattgtcc tgtggatttt gctgcttctg ttactttgtc
    12121 ttgtactgtt tcttgatctt tttggtattc ttcttgtgtt ttgatgtctg caacattcac
    12181 attcacttcg ataacatcta aatgtgtcat attgtttact tcagtactga tcaattcttt
    12241 gatttggttg taaatatctt cgatgtcttt accgtattct acgatcacat ctagatccac
    12301 agctacttgt ttcttaccta cttctgtatt gatacctgct gttacgttat ctgtgttgac
    12361 taatttttca gccatatttg agaaaaatcc gccatctaat gtcaatagac catctacatc
    12421 tttcaatgca taaccgatga ttttttggat gactttgtct tcataagtca attcaccatt
    12481 catcatgcgg ttttctcctt tttcatttgc caaaactgat ccatttgttg tattcatgtt
    12541 tttgttttcc atctttgttt cctcctatga tttaaaaaat tgatcaacta ttcctgactg
    12601 tttcaaataa aaaccgattc ctgcgccaat tgctgtcatg attatgatca acaatgtctt
    12661 gaaaaatcca atcgttaacc ataaaacagc tagcagtagt ccaagacccc caaagataat
    12721 agggagcttg tatgctgaaa atagttcttt cattatttgg ccctcctatt ccactcgaga
    12781 gtgcttgtag tctcttgtat cttcttgttc ttcataaccg ctgtatgtga ctgccacttt
    12841 gaccgtttct tttgttccga gtactttagt tacttcttct tcgatatctt gcatcaatac
    12901 acctgttttc cctactaatg aagaagttcg tttcaagtct ccgttgacat ggatatggat
    12961 tcgatttttc gttgaacgta tccgtacttt aggtgaatga atgaactctt cttcgtgtaa
    13021 atgggaacgt accaaccctt cgatcgcttt tttgtcgatt gttagtttgc catcttcccg
    13081 tttcataacg aaagttcctc ttgactttgg atagaaaaga acgactagca agatgataat
    13141 agcaagaacg gcaaatacta cagctgccca gaaaatatat tgttgcatgt agtaattcgt
    13201 taaagtaaag aagcgaaatc gttccaattg ttcaggcata atatacggcg cattgatcaa
    13261 cgcaatcgct agaaatactg aaagtagcag taaactcatg ataacaccga ttatttttaa
    13321 ccccttattc attttccacc tcctataaac ttatttttac cctgtaaata actctaccga
    13381 caatcacagt atagatagcg aacagttagc atagcatcag taaataaagc gctaccaaac
    13441 attgctggat cataacggcg ttttattgcc agtctgatac tgaaataaca attgcttact
    13501 tattctctat ttacttttga ttgctggcta tacttaaagg atattattca agattaaaaa
    13561 ttgcaaagat tatgctcagt tattattaca agattctatt tatt
//
LOCUS       DAFTHM010000072        13546 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFTHM010000072 DAFTHM010000000
VERSION     DAFTHM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.072"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(179..1795)
                     /locus_tag="L7C88_002004"
     CDS             complement(179..1795)
                     /locus_tag="L7C88_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBP9558814.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            1913..2131
                     /locus_tag="L7C88_002005"
     CDS             1913..2131
                     /locus_tag="L7C88_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558815.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            2326..2787
                     /locus_tag="L7C88_002006"
     CDS             2326..2787
                     /locus_tag="L7C88_002006"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9558816.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(2980..3219)
                     /locus_tag="L7C88_002007"
     CDS             complement(2980..3219)
                     /locus_tag="L7C88_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558817.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(3243..4766)
                     /locus_tag="L7C88_002008"
     CDS             complement(3243..4766)
                     /locus_tag="L7C88_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBP9558818.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(4784..4906)
                     /locus_tag="L7C88_002009"
     CDS             complement(4784..4906)
                     /locus_tag="L7C88_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBP9558819.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(4936..5919)
                     /locus_tag="L7C88_002010"
     CDS             complement(4936..5919)
                     /locus_tag="L7C88_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBP9558820.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(5943..6092)
                     /gene="rpmG"
                     /locus_tag="L7C88_002011"
     CDS             complement(5943..6092)
                     /gene="rpmG"
                     /locus_tag="L7C88_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBP9558821.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(6113..6490)
                     /locus_tag="L7C88_002012"
     CDS             complement(6113..6490)
                     /locus_tag="L7C88_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558822.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(6522..6701)
                     /gene="rpmF"
                     /locus_tag="L7C88_002013"
     CDS             complement(6522..6701)
                     /gene="rpmF"
                     /locus_tag="L7C88_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBP9558823.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(6716..6985)
                     /gene="rpsN"
                     /locus_tag="L7C88_002014"
     CDS             complement(6716..6985)
                     /gene="rpsN"
                     /locus_tag="L7C88_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBP9558824.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(7508..9274)
                     /locus_tag="L7C88_002015"
     CDS             complement(7508..9274)
                     /locus_tag="L7C88_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558825.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(9234..10988)
                     /locus_tag="L7C88_002016"
     CDS             complement(9234..10988)
                     /locus_tag="L7C88_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9558826.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(11098..11667)
                     /locus_tag="L7C88_002017"
     CDS             complement(11098..11667)
                     /locus_tag="L7C88_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBP9558827.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(11685..13100)
                     /locus_tag="L7C88_002018"
     CDS             complement(11685..13100)
                     /locus_tag="L7C88_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBP9558828.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(13111..>13546)
                     /locus_tag="L7C88_002019"
     CDS             complement(13111..>13546)
                     /locus_tag="L7C88_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBP9558829.1"
                     /translation="ATSLYIVFRMLPVVMISWLLVSVYTSNELLSSLEKIHLPKKIML
                     SITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQYLEFLLVPVLIRATMIAEEMT
                     ANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFLSILI"
BASE COUNT         4300 a         2587 c         1926 g         4733 t
ORIGIN      
        1 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
       61 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
      121 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
      181 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
      241 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
      301 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
      361 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
      421 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
      481 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
      541 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
      601 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
      661 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
      721 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
      781 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
      841 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
      901 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
      961 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     1021 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
     1081 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
     1141 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
     1201 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
     1261 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
     1321 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
     1381 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
     1441 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
     1501 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
     1561 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
     1621 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
     1681 catttacaat gacagcaatt tcctttccgt gatcaccgta cagaatatga tttagaagta
     1741 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
     1801 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
     1861 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
     1921 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
     1981 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
     2041 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
     2101 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
     2161 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
     2221 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
     2281 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
     2341 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
     2401 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
     2461 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
     2521 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
     2581 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
     2641 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
     2701 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
     2761 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
     2821 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
     2881 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
     2941 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
     3001 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
     3061 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
     3121 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
     3181 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
     3241 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
     3301 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
     3361 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
     3421 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
     3481 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
     3541 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
     3601 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
     3661 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
     3721 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
     3781 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
     3841 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
     3901 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
     3961 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
     4021 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
     4081 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
     4141 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
     4201 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
     4261 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
     4321 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
     4381 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
     4441 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
     4501 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
     4561 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
     4621 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
     4681 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
     4741 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
     4801 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
     4861 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
     4921 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
     4981 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
     5041 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
     5101 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
     5161 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
     5221 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
     5281 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
     5341 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
     5401 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
     5461 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
     5521 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
     5581 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
     5641 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
     5701 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
     5761 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
     5821 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
     5881 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
     5941 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
     6001 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
     6061 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
     6121 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
     6181 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
     6241 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
     6301 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
     6361 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
     6421 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
     6481 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
     6541 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
     6601 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
     6661 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
     6721 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
     6781 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
     6841 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
     6901 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
     6961 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
     7021 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
     7081 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
     7141 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
     7201 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
     7261 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
     7321 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
     7381 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
     7441 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
     7501 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
     7561 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
     7621 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
     7681 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
     7741 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
     7801 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
     7861 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
     7921 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
     7981 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
     8041 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
     8101 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
     8161 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
     8221 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
     8281 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
     8341 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
     8401 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
     8461 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
     8521 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
     8581 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
     8641 attctatagt ttcttgaaat tcttccgagt tttctctcaa agtatcgtaa tatttagtat
     8701 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
     8761 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
     8821 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
     8881 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
     8941 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
     9001 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
     9061 caaacgatac ggcaaaataa agccaacggg gctttgtatt ttctaaaact aattcgtcta
     9121 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
     9181 tagaagcttt agttaaagct tctgcgccct gatcacttaa agcaaatttg tttttataaa
     9241 aacttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
     9301 tacacttgat gtttagccat taattcatta tgatttccac gttctactat tttcccttct
     9361 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
     9421 actgtttttt ctttcatcag atgttgaaaa gccttttgta gttcatactc attatctgga
     9481 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
     9541 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
     9601 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
     9661 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
     9721 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
     9781 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
     9841 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
     9901 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
     9961 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    10021 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    10081 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    10141 aaaaaaaaca acatcaacaa gtcaacagct aatatcttgg gagtggtaag agaagttata
    10201 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    10261 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    10321 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    10381 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    10441 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    10501 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    10561 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    10621 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    10681 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    10741 aggatatgag aaaataagcc agaaaaaata taaaataaag ctcctaaagt taaccaagca
    10801 acagtttgaa ccgcataact cttagctaaa tattcatctc ctacaataat tagagactga
    10861 agaaatttgt aaatactgta atatccatag actgttaata cgacagaaaa atcagaaaat
    10921 aaagtggcta accatccgta gtatttcatt ttagggacat aactaaataa ttttttgtat
    10981 actttcattt tttcctcccc cgcattcaat ttcttctctt attcgtttac aactgttaat
    11041 gctttccgta atagcgtaaa ttagagatgt acaaacagat aaaaggtaaa ctacgttcta
    11101 ttttttgtat ttttttaaga cttttcttcc aatcaataca ccaatcatag ataaacttgc
    11161 tacaactaac actgaaatga ttccccatat acctaccgca tagtggatca ttgcatccat
    11221 tgttgcagca gattgtcctt tatctatcca atcttgacga aaacgatctg taaagaacca
    11281 tataggaatc cactgtccgg cagcactgcc taattgcatt agagcccaag acgcaacttg
    11341 aggaattgct cgatcatatc caaatacaga tagaataata tcagctaaga tcgccatact
    11401 aatcgaactg ataaaccaag gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa
    11461 aacaattgtg taaatagtaa aaattccttt tctagggtag ttatagctaa tataaacaaa
    11521 tatgattcca gataataatc caaaaatccc gggggatatg ctgtgaccaa acgccccacc
    11581 aatactacta accattattg aaaaaaagta aattactagg gaaataactg tagctaaacc
    11641 aataaaaata taatcttttg ttttcatata tattctcctc aattctattt cgttatgtca
    11701 ttaaaaatct gttctatcaa agttgaatct tctactctaa gttttatatc tttttttatt
    11761 ccaccatttt ttaaataaat aattctattg catgttttat aaagaaattc cggatcatga
    11821 gtagctataa ctactgcacc cttttctttt aagtctttaa taaggtcagc aatcctttcc
    11881 atattaatat aatccaaccc acttgtaggt tcatcaaata gaaataaatt agtttttgac
    11941 aatgaagcta tagaaaccaa taatctttgt ttttctccac cggataaatc aaacggtaat
    12001 tgatctttca ttttataaag ttccattttt tttaaaattt tttcttgctg atctttacta
    12061 actatttcat tccccagggc taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc
    12121 atttcttgca ttactaaaaa cggcgatgac aaattttttt tattttcgat tatctttcct
    12181 ttggtagggc gaataatctt catgagtatt cttagtaagg ttgttttccc cacaccgttt
    12241 ttccctacca aaccaataac atctccaact ttgacatcaa aatttatgtc ttttagaata
    12301 ttttcataag taatttcttc aacttttaat acatctgcac ttaccttttc gatataggga
    12361 acttcaatcg aactattaaa aatgtcaaat ttccttaatg cgttattgtt ttcagttttt
    12421 aacaactgaa tagttgtagt ttttacagtt ctatttttaa caaatagaac ttgatcaatt
    12481 aattctttca aatagtaaaa acgatgttca gctataacaa tagtaaatcc tttatttttt
    12541 aaatcacaaa gtaagtcagc aagtttctta gtcgctttga agtccaaatt tgaagacggt
    12601 tcatccaata taattaattt agagtttagc gataaactac atccaataga aattttctgc
    12661 cgttcaccac ttgatagcga aaaaatgttt ttatctaata tatttgaaag atctaataat
    12721 tcagctaatt cattgattct tttatccata tgctcttttg taaatccaaa gttttccatc
    12781 gaaaatacta actcactcgt tgtatttgtt gtaaagaatt gtcctctagg atcttgactt
    12841 acgtagccaa tattttttga tatactttct tgtgttaagg attgtagcga gttattttca
    12901 aataaaattt ccccaaccaa ttttccgtca taaagtcttg gaataagtcc attcattaac
    12961 tttaatagtg tggatttccc actcccagaa gaaccagtaa tcaatgtaag actgcctttt
    13021 tttattgaaa aattaaggtc aacaagcgct tgttccttaa catccttata tgaaaaagaa
    13081 acattgttaa attcaaacaa ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt
    13141 aacggaaaac aggatgatat agtctaataa gctcatgttt gttttatagt aagaacttct
    13201 tttcacagga gattctatcc cctttgttat tgcattagcg gtcatttctt cagcaatcat
    13261 agttgcacgt ataagaacgg gaactaacag aaattccaaa tattgcagag gctgaaaaaa
    13321 agacaagcga atgtttctca tttttaaaga ttctttaatc attcttattt cagaacgata
    13381 agtcggaaag aatctgatca ctactgtaat acttaacatt atttttttcg gtaaatgtat
    13441 tttttctaaa gaggataata attcattgct agtatagaca ctaaccaaca accatgagat
    13501 cattacgacc ggcaacattc gaaatacaat atataaggat gtcgca
//
LOCUS       DAFTHM010000073        13211 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFTHM010000073 DAFTHM010000000
VERSION     DAFTHM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.073"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..519)
                     /locus_tag="L7C88_002020"
     CDS             complement(<1..519)
                     /locus_tag="L7C88_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBP9558830.1"
                     /translation="MQIELQHTHDKETFEKNYKVYFELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQ"
     gene            complement(956..1525)
                     /locus_tag="L7C88_002021"
     CDS             complement(956..1525)
                     /locus_tag="L7C88_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBP9558831.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1599..1922)
                     /locus_tag="L7C88_002022"
     CDS             complement(1599..1922)
                     /locus_tag="L7C88_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558832.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2076..2888)
                     /locus_tag="L7C88_002023"
     CDS             complement(2076..2888)
                     /locus_tag="L7C88_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558833.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3242..4090
                     /locus_tag="L7C88_002024"
     CDS             3242..4090
                     /locus_tag="L7C88_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBP9558834.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRNHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4235..5176
                     /locus_tag="L7C88_002025"
     CDS             4235..5176
                     /locus_tag="L7C88_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBP9558835.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGLPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5166..7337
                     /locus_tag="L7C88_002026"
                     /pseudo
     CDS             5166..7337
                     /locus_tag="L7C88_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7449..9620)
                     /gene="copB"
                     /locus_tag="L7C88_002027"
     CDS             complement(7449..9620)
                     /gene="copB"
                     /locus_tag="L7C88_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBP9558836.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(9640..11826)
                     /locus_tag="L7C88_002028"
     CDS             complement(9640..11826)
                     /locus_tag="L7C88_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBP9558837.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(11826..12035)
                     /gene="copZ"
                     /locus_tag="L7C88_002029"
     CDS             complement(11826..12035)
                     /gene="copZ"
                     /locus_tag="L7C88_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBP9558838.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12048..12488)
                     /locus_tag="L7C88_002030"
     CDS             complement(12048..12488)
                     /locus_tag="L7C88_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBP9558839.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12562..13101)
                     /locus_tag="L7C88_002031"
     CDS             complement(12562..13101)
                     /locus_tag="L7C88_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBP9558840.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3713 a         2772 c         2344 g         4382 t
ORIGIN      
        1 ttgatttacg tctggtctat aaatcccatc agctcttact ctagctagtt cttttccagt
       61 attgtagtcc ataatgaaaa tatactcgta tttataatta gcaatgtgcc atccagctac
      121 atgcaagttt gcgttttcga tttctccgaa ctgatcaatg tgggcgtaat ttgttccatc
      181 tgtcagcgta gaatttgcag cacctgctcg agttggatca attactggtt tatcctccga
      241 agtagttgga ttatcatccg taaaaccatg agccaaatca taggctagtt tttctttact
      301 tacacccatt tcagaaagat aaccgtaagg atctgtatga tcgccccaaa tattttgtgt
      361 tacccataaa tgcgatttga ttcctggttg gttataagga gtgtctaatg ttaatggaat
      421 accatatttc attgctgaat ctcttgccaa ttcaaagtat actttatagt tcttttcaaa
      481 agtttcttta tcatgtgtat gttgtaactc gatttgcaca ggacttttgg ctcacgaggt
      541 tgtcctactc tacatcttgc tgatagatat gctgaaagga aaacaccaac attatgtttt
      601 gctttttcag ctagaacgag acaagcagga atacctttag aagatatcaa aggtttttta
      661 ggtcataaag atgtttccac tacacaagtc tatgcccata tttctcccga agtgaaaaaa
      721 agatcaatga atcaactaga aaactatata gaagagcaaa taaaaaagca ctcaaattga
      781 gtgctttttt aagctcacta tcactaaaac tatcactaat tttatttata agcgaacatg
      841 tttctatcac tgatttttta aatctagcga aaaaccctta tcttaaaggc gttcgttcaa
      901 ttctttggca aggtcttcaa agcctggctt gcctagaagt gcgaacatgg ttttcttata
      961 gctcatgtag aaaaattttc ttgatgatga ttttatccat caattgagat tgactgtttt
     1021 gctctcctat gatttcagct atgattgtcc gattttgcgg ttttcttctt aactggtagt
     1081 tgattttccc agtttccatc aactcgctaa gcatatccac gactccgcca aatccggtct
     1141 ttttcgtaat aaaacctagt gctaccattc gttcatctag attttttgct gtaatcgtca
     1201 caccagtaat gagcgagtgc tgtaatgttt gggccagctc ttccatccct tcagcattgg
     1261 atacgacgga agctgttttg ttaataggtt cttcgtttat ttcttttggt tctttcctct
     1321 ccactttcac tgtttgacga aggacatcta gttcttgcaa gagcgtttcg tattgttctt
     1381 gggtcagcat cacgccagct actttttcac gattaaatat atatacgcca gttcccgcgt
     1441 ctcgcgcttg agcaaataca tccatcggcg atcgtttcac ttctgtgatc gaagatgtgg
     1501 gaacttctaa tttctttaat tccaatggat ttcctccttt actaatcgct ttttattata
     1561 gcacagactg acttgttttg atcttttttc caaaggtttt atcggttttt gcctaaccag
     1621 taattgatat cggtaagaag tctttcgata ccaaatgaag gatggtacag atacgttttt
     1681 tgatcttcgt tatggtctag tggaaaaaaa tgatcgatga tcactagatc tgcataccga
     1741 ggcggcttat ttcgagtaca tacatgtata gagatccgtt ttcgatgtct tagcgttttg
     1801 ttcagtaccc cagcaagtct tcttgcttct tggtgttcat agcgaaaaaa aaagacgatt
     1861 ttcacttcag gagggtggac atctaaatac cctcgttcct ggagtgtttt cagtaaaagc
     1921 atcccccact ctactgcggg gtgtgcaagt gcttgttgga tcgctagccg aaattgatat
     1981 agtttatctt tggaattggg aaatttttct aatgtttcct gataataacg aacttcttct
     2041 atcagccggt catggatacc aattacgtaa cgaagtcatt cttggtaaag tacttttgtc
     2101 agctttgatt tgctttcgct ctcaaattcg ctattcagcc aaaacagcga atcaagcttt
     2161 tcagtcacaa tcgtcaattt ccgatagtct tgtgtctctt ctatccgttt ccaccgcttt
     2221 tcagtaatct ggttacagct caagcgcaaa attgctagat aatttttttc ttttattggc
     2281 aaaatctgct cctctctaaa tagcaattca ggaaacaatt caaagaatag tgttcgactg
     2341 tctcctaaaa tctcgatttc tgccggatcc tttctttgct tcaataattg gatgaacatc
     2401 tcagaaaagg actgctctcc atcatctgca aaaaaatgcg gaaaatcttt caaaaagcaa
     2461 aacagcagat atcttacttt tctttctgaa ccaaagatct gtgctttttt ataagaaaaa
     2521 gaaaggtggt actcgccaaa ccactttctc aatcgctctt gcgtagaacg atcgtacttc
     2581 tgctcgtaag gttcattcaa tagcagattt ttcagtaaac aaaacggggg tgattggatc
     2641 agaaaaacaa acaagagata aggttcgcta tatccttgat cataaactaa ctgaacggtt
     2701 ttcttatgaa gaatcagctg aatgggacag tcgctttccg ccaaacgttt cagatgccga
     2761 tccactgttt taacatcgat tttcagttct tcagctaaat cagcttttcg ccagatcaaa
     2821 tctttcatta gattgattag tgaaaataaa ttctgtgcat tttttgataa tagtttttgc
     2881 catctcatcg atcatttctc acctgatttc taaacatatt gtttgatcaa aatgggttca
     2941 ctcctaaaaa gataaaaaac tccctttcta tttatttaaa tacgcaaatc ttcctcatta
     3001 ttttttattt tactcaattt aatcgtattc tcatttcaaa acgaatgtac tttaaaaaaa
     3061 cataataaga tcactttgct tgtatgatgt attcccttcc attacaatga aataaatagc
     3121 gattttatga gaaggtgatg tgaaaatgga agaaaaaata gaagaatcca aacaaaaaat
     3181 cgatcagttg atataagaat tagaaaaagc ggtcatcagc aaacgttcaa ctatccaatt
     3241 gatgatcgtg gccctattag caggtggtca tgtcttattc gaagatattc ccggtgtagg
     3301 taaaacgtta ctggtcaaag cactagcaaa agctgtacag ggaaccttca gcagagtcca
     3361 atgtactcct gatctgctgc ctagtgatat tcttggtttt tccgtataca attcacaatc
     3421 aaaagagttt gaatttcgtc cgggaccgat ctttaccacg atcttgttag cagatgagat
     3481 caatcgtacg actcctcgta ctcagtcagc acttttagaa gcaatggccg agaatcatgc
     3541 aacgatcgac aacaatacat accctctaga caatcatttt tttgtcttag ctacgcaaaa
     3601 tccaatcgag tacgaaggaa catatccttt gccggaagca cagctcgatc gttttttatt
     3661 ccgactacaa atcggttatc cttcttttga tgacgaactt ttgctacttt tggataaatt
     3721 cgaaaaagtg ttggataact taaatgaagt attgaacagt tatgaaatag aagaaataaa
     3781 aacaaatgtg gcgaatgtct ttgtcagtcc cgaagtggca tcttatgcct tgcagttagt
     3841 gtcagcaaca agaaatcatg ctgccatcca gcttggcatc agtccacgag gaagcctttc
     3901 ctttattcag gcagcaaaag cttatgcttt aatccatggg agaaattacg tcacgcccaa
     3961 agatttgcag gatttagttc cttacgtgtt ttcccatcgc ctgatttttt acgatcgttc
     4021 attgaaggaa gacgaaaaga aacaaatcat tcatactctt gttgcacaaa ttcctattcc
     4081 tgtgaggtag attgaggtag acaatggaaa aaatcaaaga ttatttcatt aattttgtgt
     4141 tatttctggt atatttcatc attgtgcttt ttgctcttgt attcaacaat tctttaggct
     4201 ggttcttgtt ggcctttttt actctttatg tatcatggag cttgatttca ttaagcagct
     4261 ttctaaagaa actttcggtt acttgtacat tgcagccact cgtttatcgc aaaaaaagta
     4321 tgcaggttat tttttccata gcaaaaaaga gaactttttc tttacctctc cctcgtttac
     4381 aaatcggctt cccagcaatc tttgcagaaa aaaacaagag attttgattc ttacaaataa
     4441 accgcaagaa gtccaattgc tttggcagcc aaaagaaaga ggatgccatg aaacattaac
     4501 tgtcattttt acagcctatg atagtctagg acttttcaga aaaagtgcaa aaagagagat
     4561 ctcttttcct gtgactgttc tgcctgcttt ttgtaagatt caagcagaaa aattacagag
     4621 agttctggaa aaaaaacagc agctgaacgc gtaccaaaga ggtcttgatt ttcgggaaca
     4681 tcgcgcttat cgtccaggtg attctttcaa ccgaatcgat tggaaattgt ctgctcatac
     4741 tcaagagtgg ttataccgtg aatacgatta tcaagaagaa gaatgttctc ctcttttttg
     4801 cttttggggt ttgcccagtc caaaatttga acctctgcta gacttgtatt tttctttatg
     4861 gcatttgaga aaagaaaagc agccggaact tctgatatta ggcaaccgcg cctttcatgg
     4921 caaagacccc ggtcatacct attttgcttc tttggaagct ggcgatgaga aagctttttt
     4981 cgcacacttg aaaaaatatg caaaaaaaca aatcgtcctc tttgttcctg agaattctcc
     5041 tgaagtctca gaagctattg aaacattgtc aaaagatcga acggtttatc ttgtttattt
     5101 cgtagaaaaa caactcatgg tccaagaaaa agacaagata tgttcattgc caggaggtga
     5161 atggattgac gattaaacgg gaaaaatggc tgcgtggcgt ttactccttt gtgatactaa
     5221 gtgtaggtgc tccgatattt gtagtagcta atcaattgca aaacagctac cttcttatcc
     5281 taactattgg tgtcctatgc cttattgtct gctgtattcc taaaaaatgg gtacgtttgc
     5341 tgctttcttt gccagtaatg ataggttgtt tgtttttata ttttccttcg aagacatttt
     5401 ccatattatg gatcttacag tttttttcgt cagtcacaga ggaattcttc catctatccc
     5461 aaggtaaact ttattatttg ccagaaaaga cagctttttt tctcataatg ttgctgatct
     5521 atttatttat tacattgacc gtggattacg actattggta cgcacccttt ctttctttga
     5581 tggcttactt catgatgctt accgtttttc ggaaaaaaga tttactgtac gaaatgattg
     5641 cggtagtaac tgttttgttc gtgtatctgg cagcaaggca atttttctcc atccggttgt
     5701 tgtcgggaaa cactcgattc cagtcattga ctacagttct gcttatttgt ttcttaactt
     5761 ttagcgctat cttgccttta tatcttccga aagtacacca atctctcgag gaaacgagtg
     5821 aaccgatccg agaatatctt aatgatgaag ggctttatga cacactccat gagtatcaat
     5881 taaccggaag tgcaagaaca ggcttcagtg agaatgatga acagcttggt ggacctttat
     5941 atgataatgg cgaagttgtt tttacagcga accaaaaagg aaatggctat tggaagatcg
     6001 aaaataaaaa tcattacacc ggttctggat ggatagaaga tcaggacgca cccatccaac
     6061 caatccaaga attccctgtt gacatcacga gctaccaaac cgttatagaa gacaaagaaa
     6121 acattacatt gaccctaaaa aaacaagttt tcttacctta tccttatgga aatactacct
     6181 tgactgattt ttcattagct agtggacaaa cgctttacta tttgcctgaa agccagcgat
     6241 tcattcctgt cccgaatgaa tcgacacgtt ctgcaacttt acaaacagaa aggttagttt
     6301 ttacgagaga agaattaaaa agcagtcagt taaaagctga tgatttagaa aatcagcaga
     6361 caaatcttca attgccaaaa agtttgccta aacgtattga ggacttggcg gtcgaattga
     6421 ccaaaaatga agcaacttta attcgtaaag tcgaagctgt ctaacagtat ttaaaaacaa
     6481 gcggaaattt ccgctattcc aaaacggata ccgggcatac tccaaaagaa cacgattatg
     6541 tggattattt cctctttgat tcaaaagtcg gctattgtga caacttttca acttctatgg
     6601 tcgtccttct tcgaacactt ggtatcccag ctcgctggac aaaaggtttt acaaatgggc
     6661 tcagaacagg cacagataat caagggaatg aggaatacag cattctcaat agtcatgctc
     6721 attcttggcc agaggtatac tttcctggat ttggctggct tccatttgaa ccaacccctt
     6781 catttgccaa tccaatgggt tcacaaccag ttgctgaaac aaccgaaacc gtccagcctg
     6841 ctatcgaaca accaaatgaa agcgaaaata tggcagaaac tatttccagt gagagatctg
     6901 aggtcattcc atcagaagaa acaacactca caccagctta taaaatcgtc ttattcagcc
     6961 ttggagtgtg tttatccgtc ttgttgttct ttctattgtt attcagaaaa tctctgcgct
     7021 ggacaagtta tcttatctat cttcattttt ttgcttctac taatacgatt gcatatcaaa
     7081 aacttcttaa ccctttggaa acattggtac cgcgcaaacc cgcagaatct ttgcaggaat
     7141 atagcctgcg aatagaacaa gaattcaagc tagatctgcg tttcattcga ttaactactc
     7201 aatatgaagc agaaatatat ggacgacaag cagatccggt aaaattcgat aaaaaaacct
     7261 atttagaaat aacgcatata ataagaaaaa tggtatacaa aaaaattctg acaaaaggga
     7321 gccgcttcaa aaaataagat aaaatttctg gagaatctac ttctggaatg ccgagaacca
     7381 gctgattgag tatcgattac tcgaaaaaaa ggttgtgaca cgttttttgt cacaaccttt
     7441 tttcattatt atctgatttt caatgtcaaa gcatttagag ctacaactac cgtacttaac
     7501 gacatcaaga cagcaccaac tgctggactt aatatgatac caattggcgc aagaattccg
     7561 gctgctagcg gaattgcaag aatattgtaa cctgcccccc accagaggtt ctggatcatt
     7621 ttctttcgcg tttgcttggc tagatcaaga aaatgcaaaa tatcttttgg atcgctgttt
     7681 gtcaatacga catccgcaga atcgattgcg atatctgtcc ctgcaccgat tgccatcccg
     7741 attgaagcac gggctaaact tggcgcatca ttgatcccat cacccaccat gattactttt
     7801 ttcccttggt caaggtattt ctggacaaca gcttctttat catctggtaa taaaccgcca
     7861 taatattctt cgatccctaa ataatctgct actgcttggg cagcgttttt attgtcacca
     7921 gtaagcatga caggagtgat ttttctttct ttcaatgttc ggataaattc ttttgcttct
     7981 gtttttacta cgtcacctaa agcaacgatt gcagctagat gattttctaa aatcaggaag
     8041 ctgatggtat ttccttgttc ttggtaaggt ttcaataatg cttgttctac gtttaatccg
     8101 agacgctcaa cttctttttc attaactatt ttcacttgtt gttttttgac tgttgcctct
     8161 agcccgactc ctgaaagatt ttttagattt tcagcttgat aaggcttgat ttcatgttct
     8221 ttcaaataat tcataatgcc aacagccaat ggatgattgg cattcgcttc caaggctcct
     8281 agatattgaa ggatttcatt tttattgaac gcatcatcaa gtacttcgac acccgttaca
     8341 gtaaattttc cttctgttag tgttcctgtt ttgtccagca tgatcacatc tagatcattg
     8401 gcttgctcca gtgcattgcg gtttttcaaa agtaatccgt ttttagctgc tattgatgtg
     8461 gaacgagcaa caactaatgg gatagctaaa cctagagcat gaggacaggc gatgataaag
     8521 actgttacca tacgttctaa tgcattagga agatctgtca agaacaacca ggcgatgaat
     8581 gccaggatac ccacaattaa tgcgacataa aacagccatt ttgccacttt gtcagataat
     8641 gactctagct tggatttttc tccttgtgct tttcgcacca tttccataac cttcgctaga
     8701 taaccatttt caccagttcc agttacttcg atttcgatcg ttccatcccc attgatagaa
     8761 ccgccaatca ctttgtcatt ggcttgtttt ttgattcctc ttgattcgcc agtcacagct
     8821 gattcgtcaa caattgtttc acctttcaag attacaccat ctgttggcat tttatcacca
     8881 gaccggacga tcaaacgatc accttcgttt acttctttca atgaaactgt ctcttctttt
     8941 ccatctttcg tcaagcgttt cactgattct ggcagtaatt ctgctagttt ttgtaaagca
     9001 ttgctggcat tcgacacagc attcatttca atccagtgac ctagtagcat aataacgatc
     9061 aaagtagcca attcccagaa gaaatccatg acgtgtgtat gtggattgag cagatttgcg
     9121 ataaacgaat agacactata aatatatgca actgtaatcc ccatcgcgat cagtgtcatc
     9181 atagcaggac ttttttgttt caattccatc ttagctccac ttaaaaatgg ctgaccgcca
     9241 tagataaata gtatagttgc taagatcaat acgagccaat cagaaccagg aaacgttact
     9301 tgaaatggaa attccattcc catcattggt gaaaaaagaa tgattgggat agctaggata
     9361 agcgatagcc aaaatttttg tttgaaattc cccatgtgca tggaatgatc catgccgccg
     9421 tgttcgtgat ccatgtgcat cgaatggtcc atttgtttgc tgtttgctat atctccatgg
     9481 ttatgtccca tgtgcatgga atgatccatc tgactatggt catgtttcat ctccatctgt
     9541 ttttcatgag attctgtact ttctttgttt actacttctt ttttatgctc atgttttttc
     9601 tccatatcgt tcccattcat ttttactcca tcccttctct tactttttca tgtgtcgatt
     9661 taagcacagg gagttcaaca atacactgac ggaactaaac gccatcgctc ctcctgcaat
     9721 gattggattc aaaaagccta gtgcggcaaa aggaatacca atcgtattat agacaaaagc
     9781 ccagaaaaga ttttgtttga tttttctcaa tgtcaaccta gacaactcga ttgtttgtgc
     9841 aatggatgcc aaactgctat tcatcagcgt cacatcggct gtttccatcg caatgtccgt
     9901 tccacttccc attgccatac cgacatcagc taatgctaag gccggtgcat cattgattcc
     9961 atcgcctgcc ataccgactt ttttgccatc tttctgaagt ttttctacgt aggctgcttt
    10021 atcctctgga agtacttcag caaagatatg ctttggatca ataccaactt gtttaccaat
    10081 cgtttcggct gccagtttgt tgtctcctgt cagcataaaa acatctaatc ctttattctg
    10141 gagctgcttg attgcttgtt tgacttctag tttgatttga tcagccacgg caatcaaccc
    10201 gatcacttgc ttttcatcag ctaaaaacat gactgttttt ccctgctgtt ctaattctaa
    10261 cgcgtgttct tggtattcat caaatgatag gttcaattca attaatcgtt tacgtgtacc
    10321 cgcaaaatag cgtactccgt taatcgtacc gctgattcca gcacctgggt gggctgtaaa
    10381 atcaatcata tcgtatgttg ctgcttcttg cagttttccg tattccacga ttgctttacc
    10441 tagtggatgt tcagaagctt gttctaaagt ataaaaaata gataggactt ctttagaacc
    10501 gactagatct gtaactttgg gctttccttc tgtaatcgtt ccagttttat ccaaaacaat
    10561 gctgtctaag tgagcagctg cttctaatgc ttctccgcct ttaattaaaa ttccatttcg
    10621 tgcaccaaca cccgttccta ccataatagc tgttggagtc gctaaaccta atgcacatgg
    10681 acacgcaatg actaatacag agacactatg gatcaatgcg agttgccaat caccagtgat
    10741 caaacctgta gctatgagcg tgataaacgc gatgactaat acgatcggaa caaaaatccc
    10801 tgagatccga tctgcgattt tttggattgg ggctttgctc ccttgagcat cttccaccat
    10861 ttgaatgatt tgcgctaata ctgtctgctt gccgacttgt gtaacttcca tgtgaagtag
    10921 accattcgta ttgattgtcc cgccaaagag cgtgtcatcc ggattctttt ctacaggaag
    10981 attttcacca gtaagcatac tttcatctat cgcactgctt cctgaaataa ttcgaccatc
    11041 tgctggaatc tgctcaccag gacggatgac tagttgatca ccaacgacta cttcttcaat
    11101 cgctaacgtt tcttctttcc cgtttcttat cacttgggcg gtttttgttt gaagagacat
    11161 caattgtttg attgcattac ctgttttcgt ttttgctgta tgttccaaat atttgccgag
    11221 caaaatcagc gtgatgatca tactgctgct ttcaaaataa agatcttggg ggtgtccacg
    11281 gaaaaatccg ttgtaaatgc tcaatgcaaa ggcagccgat gttccaattg ctaccaatac
    11341 atccatattt ggtgctttcg tcttgattgc atggtacgca cctttataaa aacgagcacc
    11401 gacataaaat tggacaggag cagacagcac taactggacg attggaaaat gaaaaaagtg
    11461 aacaatcgcc gcatggcttc ctaacatcat agcaatcatt gacaacatca acggcaaagt
    11521 caaaaccgta ctcaatataa gatcgaatag catttttttc aaatacgctt gcttttcttc
    11581 tgcaattttt tgtttgtggg cttcatcgta caaaattgca ccatagccga tgttttctac
    11641 gctttggatt aatttttcag tggtcgtccc ttcatatttg acacttgctt tttcagtggc
    11701 caagttgact gtggcattga ccacaccagg ttgtccgttc agctcttttt cgatcctagc
    11761 agaacaattt gcacaagtca tacctgtaat gacgaacgta tccattttgg tttctgctgt
    11821 tgccatcaaa tcacctctgc tttataaccc aatccattga ttgcttgaca aatcttttcg
    11881 gattgaactt ttgtttcatc aaacttgacc gtaccgtttg cttttttcaa atttactttc
    11941 actttttgca cgccgtcaag tgcgcttact gtttcttcta ctcttgctgc acaatgattg
    12001 cagctcatac cttcgattga aaattgttgt ttcatttttt cttcctccta ttgatgttgt
    12061 ttacattcac attgacctgg gatacagtta cattcgatcg tatctactgg ttgcttttgt
    12121 tccagttgtt tcaaaatctc attgatatct tcttgagtca aagtggcttc ttctactaga
    12181 tccgcaatcg tctctccaat cctttttgca cagatatggg aaaaaagatt ttccgtcgca
    12241 ctgcgaactg tttccatctc cgagacagct ggataataaa tgaatttttt tccttcttgt
    12301 tctgtccaga tcacttcttt ttttaccaaa cgacccagca aagttttgat cgttgctggt
    12361 ttccaatcca tcgaatcagc taagatctgc gtgatttctt gggctgtcgt ctgtccaagt
    12421 gtccaaataa cacgcatgat ctcccactct gaatcactga tctttactgg cgttttgact
    12481 ttttccattt atttcacacc tttcgtttac aaatgtaatc attatcttat gaatacagat
    12541 tacacttgta aacaaaaact gtcaattatt tttgctctct attttcaatt tagttaaaaa
    12601 ttcttgtttc tctcgtcttg ttttaaggat gatcagttta tttcttgcat tagctacttg
    12661 gatcagctgc tgtattttcg gttcattgtt ttcttcaaaa tgccagataa aagataaaaa
    12721 ttctaagtat tccctgttta gtttctccga aaatgattca ggcatatctg gccgagattt
    12781 tttgtttatc tttcttttta gagaacgcca aactactcgg tagatggcga gataacgcgg
    12841 cactttaagc caaatgatct tatctgcttc tttaatcctt tcctctaatg tagaagtata
    12901 atttccttca acgatccatg acggattaga taccataaac aattgctgtt cttgcaaaaa
    12961 ccactttttt gcctgaatac tgtagtctgt tgtatgccat aaaaggtcta gcggcagtag
    13021 cggaaagtcg gtgatttctt tgatcttcct tgcgagggtc gattttcccg acccactttg
    13081 tccaatcacg atgatcttca ttcttctccc tcacttctct ttggaatttg gttcgatcat
    13141 accacttata acgccgcaaa aaaacaaggg actgtgacaa aagtcgtgtc aaagtccctt
    13201 gtttcgaata a
//
LOCUS       DAFTHM010000074        12979 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFTHM010000074 DAFTHM010000000
VERSION     DAFTHM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.074"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            71..1051
                     /locus_tag="L7C88_002032"
     CDS             71..1051
                     /locus_tag="L7C88_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9558841.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            1173..2591
                     /locus_tag="L7C88_002033"
     CDS             1173..2591
                     /locus_tag="L7C88_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBP9558842.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            2662..4131
                     /locus_tag="L7C88_002034"
     CDS             2662..4131
                     /locus_tag="L7C88_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBP9558843.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            4141..4608
                     /locus_tag="L7C88_002035"
     CDS             4141..4608
                     /locus_tag="L7C88_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBP9558844.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            4644..5516
                     /locus_tag="L7C88_002036"
     CDS             4644..5516
                     /locus_tag="L7C88_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBP9558845.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            5597..8131
                     /locus_tag="L7C88_002037"
     CDS             5597..8131
                     /locus_tag="L7C88_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBP9558846.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            8287..9060
                     /locus_tag="L7C88_002038"
     CDS             8287..9060
                     /locus_tag="L7C88_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9558847.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            9053..9844
                     /locus_tag="L7C88_002039"
     CDS             9053..9844
                     /locus_tag="L7C88_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBP9558848.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            9854..10345
                     /locus_tag="L7C88_002040"
     CDS             9854..10345
                     /locus_tag="L7C88_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9558849.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            10363..10773
                     /locus_tag="L7C88_002041"
     CDS             10363..10773
                     /locus_tag="L7C88_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBP9558850.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            10777..12177
                     /locus_tag="L7C88_002042"
     CDS             10777..12177
                     /locus_tag="L7C88_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBP9558851.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            12200..12574
                     /locus_tag="L7C88_002043"
     CDS             12200..12574
                     /locus_tag="L7C88_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBP9558852.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         4493 a         1748 c         2617 g         4121 t
ORIGIN      
        1 gagtcaaggt tcttggaatg tcgaatagtc gagtaggtag attttctatc tacaaccttg
       61 ttgtttaaaa atgaaaaaaa ttggaattag agaagttgcg aaagaggcaa atgtttctcc
      121 tacgactgtg tcgagggtat tgaatgatcg tggatatttg agtgaggaaa caaaaagaaa
      181 agtttttgat gccatgaaaa aattagaata ctatcctaat gaactggcga gagcactttt
      241 taaaaacgaa acatataccg taggtttgat ttttcctaca attactaatc catttcacgc
      301 tgagttaatt caagatatcg agttcgagct ttccagcagg ggatataaag tgttgctgtg
      361 caatagctta aacaatccaa caaaagaaaa agagtacttg acgatgttga gaaagaatca
      421 ggttgatgga attatagtag gaacgcacaa taaagatatt gcggattatg atattccagg
      481 gctacctatt gtagcgattg atagaagtct tggtgaaaat acagttacag tatcttgtga
      541 taattacagg ggtggggaat tagctactca actacttgta aatcatggct gtcagaatat
      601 actgtgtatt cggggagata gtaagataaa gctacccgcg aatagtagga ctttagcata
      661 taaagatgtt ttgaataaat tcatgctgga accgttagtc ctagaagtac catttgtaaa
      721 agaaatcaat gaaaaaaatg aaataattaa gacatatctg gaaactcatc caaatattga
      781 cggggttttt gcaggagatg atttattggc ttctttggcg attaacaact taggaagttc
      841 gggcaaaaga gttccaaaag aggttaaagt gattggattt gatggagctc aacaaacatt
      901 gatttataat ccagaattat caactattca acagcctata gatcaaatat ctaaagtagc
      961 agtaaaaaaa ttattgaata tgattaaggg cgaaaaggag acggatgaac tttcacttcc
     1021 agtaaagctc ataaaaaaaa atacagcata agttaaatcg gcgaaaaatt ccttcgtcga
     1081 tttaaaaata tttttatgaa acgggttgac atatgaaacg ggttgacata tattagttgt
     1141 gaagataaaa accttttcac tggaggaaga aaatggagaa attattaatt aaaagcaata
     1201 atcatcaact ttactaccaa cctaaggatg tttgggtcgg agatgttatg ccttacggga
     1261 aagaaggaaa attctttatt tatcatcaac gtgatactag aaatccagtt ccttttggag
     1321 aaccgtttgg ctgggcttta gcaactacga aagattttgt tcattttgaa gactttgggg
     1381 aatctctttt aagaggggat gacaatgaga gagaccagtt tatctacgct ggttctgtat
     1441 ttgaggcaaa tggaaaggtt cacgcatttt atacagggta taatcgtgaa ttcttagcgc
     1501 agggaaagac atctcaagtg ttgcttcatg ctgagagtga tgattttgtt cattgggaaa
     1561 aatcagaaac agcattggag ttagaaccac aagaagggta tgatattcga aactggagag
     1621 atccatttgt cgtttgggat gatgaaaaag aagaatattt gctaatttta ggggcgcgaa
     1681 agggtcagga taaacatcta caaaccggac gtttagtgga atttacatca aaagatttaa
     1741 ctaattggga attcaaaggt gatttttggg ctccgggatt gtataccatg tttgaaatgc
     1801 cagaactttt caagattggt gactggtggt atcttgtcta ttcagaatac tcagatggaa
     1861 ataaaatact ctatcgaatg agtcaaagtt tggaaggtcc ttggattaag cctaaagatg
     1921 aagcttttga tggacgggct tattatgcag gtagaacagc ttatgatgga aaacgtcgag
     1981 tcctatttgg atgggtacca acaaaagatc aagaaaatga taaaaacaat tatttatggg
     2041 gaggtacttt ggttcctcat gaagtctatc aaaaagagga tttttcactt ggggtaaaac
     2101 ccatagacga agtgtggaat gcattcataa atttacatga tattgccgat gtagagatag
     2161 aaacagcaga cacaagagaa gaagtaacgc ttgtcaaaaa tagtggaact ttgtttaatt
     2221 tagaaacaac aatttcattt gatgagaatc ttagtgactt ttcactgaga ttatataaaa
     2281 accttgagac agatgaatct tacgaatatc gcttcaattt agatgagggg cgtcttacat
     2341 ttgataaaaa cccttgttac ccttggtttc aatatatgga taaaggactt attagaccta
     2401 tatctttaaa gcctaaccaa tcttataaac taaaagtgat tgttgatgac aatataatga
     2461 cactttatat tgatggaatc gctcttaacg ctcgtgtaca tggttgtttt ggtcaagcaa
     2521 ttactattac agcaacaaat ggatcaatga ctgcaataaa taccaagttt tcaaatgaaa
     2581 taaagaaata ataaacgtca atcatgtggc aggtctgaaa atcaaacatg acctgtcaca
     2641 tttaaaaggg aggataaatg aatggactac aaaaaaattg ccgaagatgt attggaaaac
     2701 gttggaggaa aagagaatat ctcaagcgct acacactgca ttactcgttt acgtttaatt
     2761 cttaaagaca aaagcaaagc gaatatggaa atgcttgagg aaatagaagg tgcaaaaggt
     2821 gttcttttca atagtggaca gttacaagta attttcggaa caggtataat tgaaaaggtt
     2881 tacaaagagt tcgttgaatt gacaggagct aaggaagtat ccgtttctga aatgaaagac
     2941 gaaggagtca ataattcagg aaatagactt caacgagctt ttaaagtttt ctcggatatc
     3001 tttattccga tcattccagc ttttattggg gcagcaatgg ttttaggaat tcgttcgttg
     3061 attaccactc ctggaatgtt tggaatggat ggctcattcg ctgatcacaa tgtattccta
     3121 aatgatttat ccaaatttct gggtattatt gcaaccacat ttgattattt accagtttta
     3181 gttatgtatt ctgcaacaaa acgttttggc ggaaacccta ttttaggatt acttgtagga
     3241 tttgttatga ttcatccagg actagccaat cggaatgatt tcgtcatggg aactataaag
     3301 cctgattatt ggcatttatt tggattaagc attccagcag ttgcgtttca agggggtgtt
     3361 tttccagcaa ttttgacttc ttggttttta gcaaaagttg agaaaattac aaataaatat
     3421 tctcctcaag tacttgctta cattttagtc ccaactgtga caattgttct tgccaacttt
     3481 gcactatttt tagtgtttgg tccattgggg aattttatcg gtaatgtttt aggtggaatc
     3541 attgatttcc tatatatgaa gatgggtgcc tttggtgctt ttgtttttgc aggcgcgtta
     3601 caaccattag ttgtaacagg aacacaacat gctattcaag gtattgaggc aaacttagtc
     3661 gcaacaactg gattcaatta tatccaacct atttggtcag tttcaattat tgcccaaggt
     3721 ggcggttgta ttggtatgta tttactcttt aagaaaaaat ctaaagatag agatattgcg
     3781 atttcaagct ttattccaac actggtaggt attactgaac cggctatctt tgctgttaat
     3841 ttgaaatatt caatcgttcc ttttgtttgc tcgtttattg gtgctggttt tggtggagca
     3901 tttatgaaaa tttttgatgt aaaagccatt ggacaaggat tgactgtatt gccaggtctg
     3961 actattgcta atccagttct tccttatata tttggtaatc tcatagcatt cattttacca
     4021 atcattttta ttctcgctta tgataaatat aaagtgttta tccctgaagc taaacaccgt
     4081 aaatttgcag aaaaaactga ctcaaaaaaa ttgccagttc aagtaaagtg agatgagagc
     4141 atgttaaatt tttttagaaa aaatgaaata agcgttgtag cacctgcaac cggtgttttt
     4201 gaaaaactgg agaaattaag tgatccagtc ttttcaaaag gaatgatggg acaaggattt
     4261 gcaattgatg caaaaaacga aacgattgta tctccaatcg atggttttgt ttcaagtatt
     4321 tttcctacaa aacatgcctt aggaataaaa acaaaatcag gaattgagat acttgttcat
     4381 gtaggaatag atacagttga gctaaatggt gagggatttg atattaaagt tcaagaagga
     4441 caaaaagtta aggctgggga tattcttatg accattaatt ttgtagtttt tgaaaagaat
     4501 cacaagacta aagatgtcat tgttgttttt ccagactacc aagacgaaat tttcattccg
     4561 aaacttgaag aagtaaaaca aggacaagaa ttgtttgttc ttggctaatg ataagtaatt
     4621 aataatagaa tcgaggaaaa tgtatggttt ttggggctat tgaagctggt ggaacaaaat
     4681 ttgtttgtgc cattggagat aaagatttga acatatttga aaaagtcagc tttcccacga
     4741 ctacacccaa agaaacaatg aatttagttt tagatttttt taatcatcat aaagatgatt
     4801 tagaaggtat cggagtggga tcgttcggtc ctattgatat tcattgtgaa tctaaaacgt
     4861 atggcttcat tacatcaacg ccaaaacttg cttggcagga ttttgatttt attggaagtt
     4921 taaaaaagca acttaatatt ccaactgctt ggacgactga tgtaaatgcc tcttgctatg
     4981 gtgaatatgt ttctggaaat ggcagaggcc tttcaagtgt tgtttactat accgtaggaa
     5041 cgggcatagg aggtggcgct atccaaaacg gaaacttcat tgaaggtttt agtcatccag
     5101 aaatgggaca tatgcttgta aaacgacaca ataaagacaa cttttctggg acatgtccat
     5161 tccacggaga ctgtttagag ggcttagctg ctggtccggc aatcgaaaga agatcaggga
     5221 aaaagggaca agaagtgact gaaaatgacg ttacttggga aatagaagct tattacattg
     5281 ctcagtgtgc atataataca acattgatgt tatcacctga tgtcattata tttggtggcg
     5341 gagtaatgaa acaaaaacac ttaaaaaaga aagtacaaga taagtttatt gagttgatca
     5401 acggatatgt cgctattccc gatgttgaca attatattat gacaccaaaa ttgttagata
     5461 attctggtat tgtaggttgt ttagctttag caagagacgt taaagaaaaa tcttaatttg
     5521 gaaaaaagat cgtctcgact atttgtttgg ttgatgcgat ctttttttca attagtaatt
     5581 gaagggacgc ctaaaagtga aaaaaaaaat gaaagatgaa gtattagagt atatcaaaaa
     5641 taatttaaag tattacgatt tttctgctca agatattgca atgaaatttt gtattaaaag
     5701 aaatgtcgct tcccactatt tgaatcagtt attttcagat ggaaaattac taaagaatga
     5761 ttctgttaga ccagtaatgt tcaagtataa tcaacaaaag ccaaaagact gcttttctaa
     5821 gtttattgga gcagacatat ctttgaaatc cactatagat aaatgcaaag ctactgtaat
     5881 gtatccccct aatggcctcc cattaataat aaaaggaaac agtggcgttg gaaaaagttt
     5941 tttagcaagt ttgatctatc agtatgctct tgatagaaaa gtaattcata atgacgcaaa
     6001 atttgttgtt gtgaattgtg cagattatgc aaataatcca gagctattgt cagcagtttt
     6061 atttggatat aaaaaaggag cctttactgg ggctgaaaaa gatactgcag ggatgctatc
     6121 ttctgctaat ggaggatacc tttttttaga tgaggttcac aatctaagtg cagaaaacca
     6181 agagaaattg tttcttctta tggattctca aaagtatcgt aaacttggtg aaagtgtgca
     6241 atgggagtat gcaaatgttc gccttatctt agccacaaca gaagataaaa atacctcttt
     6301 gttagcaact tttagaagac gcatcccagc tgaaatcact ctgccagatt acaataatag
     6361 aagtacatct gaaaaaattc aattattatt tgaatttctt aaagatgaag caattacgat
     6421 tgattcaaaa atattttgtt cgattgaact ttttactgat cttttatcga aaacatttga
     6481 aggaaatgtt ggagaattga ggaatgaaat caagcttctt tgtgcagaag gttatttagg
     6541 aaataagaga aagtcttcaa tttatttagg ggacaaacta gacagcggtt tttggataga
     6601 tccagaaatt agtatagatt taaaaaaaat gtttcttaaa tcactttctg aaattgattt
     6661 gattgaactt tttcaaaatc acatttcaat tgaagaaagc atgagtcaat taagagatag
     6721 aatacttaaa gagtgtgcag gttcttctga gtataattat ttagaaagtg acgaatttat
     6781 agcattaaga aactatgttg ttaataaaat atcaccaatt attgattcga caggtctatg
     6841 tttattagat gaattcttgg cggatatcag tctatttata atgtttattg atgtaattga
     6901 agaaacatca agaaattttt tgctgtctaa gttcagaaaa tttcgtatga aaaatgataa
     6961 acaaaaatta ttggcaaatg agatttggag tagtttagaa gtcgaagaaa gtaaacaaga
     7021 acttttgttg aaatggatac tttttcttgt aaagaagttc tatgtgaaaa taccagaaac
     7081 ccattgtctg atagttatgc acggtaaaat aacagcttct gcgatcgcaa gggaaacaaa
     7141 taagttgctg aatacatatg tttatgaggc tttcgatatg ccaattgaag gtgagactag
     7201 tgacttaatt aacctaatca acaatttttg taaaagtata gatacgacga atggactcat
     7261 tctgctagtt gatatgggat cattggaaca aatgtatgaa aaaattgaat ccaatgtaat
     7321 aggtgatttg gtaattttaa acaatgtttc tacagcttta gcgattgaat gtgggattca
     7381 agtttgccaa aaaaagccaa ttagtcattt ttaccagatg gattttgatt cgtttcaagt
     7441 taaagttcag tattataaag gattatcaca aaagaaaaat gtaatagtat cttgtctctc
     7501 tggtgagggg atttctgaaa aagttaagga tattttaaaa cggtatctcg ataatcaagt
     7561 ggagattttg atttttgatt ttaacgcatt aaagaaaata gcaaaggaaa aagatactat
     7621 gatttttaag aatacaattt gtgttctttc aaccactgaa ttttacattc aaggaatcga
     7681 ttgtttaaat ttagaaaatc taattaatgg gaatcaaacc ttagaaaaat taaataagta
     7741 tatggactcg gatagctgtg agttctgctt aaatgaatta gttaaactct ttactattga
     7801 aggcgctagt actaagcttc gctttttaga ttccaaaaaa gtattcaatg agatagaaaa
     7861 agtactatat ttgtatgaaa aatattacga tgtcaaaatc ccaagttttc tgagaattaa
     7921 tctatttcta catctttctg gaatgattga acgaattatg attggtgatg gaataacaaa
     7981 tgaacatttg aaagagggag cgcaactatt tgatactttt ttaaatgtat caaaagattt
     8041 tttttcagaa atcaaagata tttactgtat tgaaataccc aaaggagagt atgagttaat
     8101 ctatacaatt tttgagcaga ctattttcta aatagcatac tagcgtctaa aaaaatgaaa
     8161 gggtgtccaa agtatattta gacgctcatt taattaatat ttactgtatt ttcccgcttt
     8221 attggataat gttagttggc acagtaattg cttatataaa agtataagaa gaaaggagag
     8281 aacaaaatgg cgttttggca aacattttta gttgtgttgt atggattttt cattaactgg
     8341 gataaggaag ggcccaaaat cggaacctcc caacctgtcg ttgcaggttt cttgaccgga
     8401 cttattatgg gagatattca aactggactt tatatcggtg ggactttgca attaatgaca
     8461 ctaggtatta ctagttttgg tggtgcatca gtaccggatt atcaaacagc agcattgatc
     8521 ggtacttatt tagcaatctc aactaaccag gatgcttcta taggaataac tttagcaata
     8581 ccggtagcaa tgttaattgt acaactagat gttctaaagt ggtcaacaaa catttttttt
     8641 caacaaaagg cagaaaaatt cgcacaaaaa gaagattatc aaaaattaga gtggatgcaa
     8701 tatttggcat caattaatac aagctttgta tctggaattc ctgttttgtt aactgtgata
     8761 ttaggcccaa cgttagtggg aagtgcaatc aattatattc ctgaatgggt taccggtggt
     8821 ttaaaggtag cagggggact attacctgct gttgggatag gaatgctact taaatattta
     8881 cctacaaaag attactttgc ctatttgtta gttggtttcg ttttggcagt ttatttccaa
     8941 ataccaattt tagggatttc gttacttggc gctgcaatcg cactaatcgt atataaaaat
     9001 agatcaaata atactcaagt agcaccagct gcaacaggag gttttgacga agatgaataa
     9061 gaaactgaca aaaatcgaca aacaagtaat tttccggtgg attctcaatg gtgcaacttc
     9121 attaaattat gaaaaaatgg aagggttggg ttatgcgtat tctatgcttc cttttatcaa
     9181 ggacacatat aaagatgatc ctgaaggaat gaaacaatcc gttttagctc acttacaatt
     9241 ttttaacact acgccgtata cagcgcctta cattattggt atgaatgttg gaattgaaaa
     9301 agaagaaaaa aataagtctt tggaagcagt aagtgctctg aaaacaggtc taatgggtcc
     9361 tttagcggga attggagata gtgtatttgt agttattcca tggactattt ttggagcaat
     9421 tgcagctaat atggcattgg aaggtagttt tgttggaatt attttgtgga tactggcatc
     9481 aattttatta aggattactg cttatccttt ataccttgct gggaaagaat cgggtgcgag
     9541 cctactaact caaattgaaa caaaattaaa gtctattact gatgcagtat caattttagg
     9601 gttaatggtg gtcggtgcac tcattgccac agttgtaaaa gtgaatgttg gctttgaatt
     9661 taaacaaggc gacttaacaa tgaccggaaa tgaaatcttt gatcaagtta tgcctggttt
     9721 attacctgca tgtgtagtag caattgtgta ttatttgtta ggacgaaagg ttaaaccagt
     9781 ttatgtaatt ctattaatct tagtagtttc tattgcgtta agagcgttaa atattttgaa
     9841 gtaggtgttg aatatggatg aaaaaatgaa aggtattata catgttcgta ttgatgatcg
     9901 aatgattcat ggacaagtag caacacaatg gacaaatcaa ttgagtgcta acagaattat
     9961 ggttattaat aatgaagtag ccaatgatga cgtaaaaaaa gctgtagttc gcctcgctgc
    10021 accacctaat gttagaactt caataattac aagggaagta gcagttaaaa atattctttc
    10081 tggtaaatat gaaggacaaa aagttcttat tgttgcagtt tctccaatcg atgttaaatt
    10141 tttgattgat aacggtttac caataacaag tgtaaacgta ggaaatttat caagaaggaa
    10201 tggaacagaa cgcatccgtc cgacgataaa tattactgaa gaagagagag aggcttttaa
    10261 agaactaatt agtgatggag ttgaagtgac agtgatacaa actcctagag attcaaaaga
    10321 atttttaaag gattttattt attaagaaca gaggatgagt ggatggagtt tataattaca
    10381 tctcatggaa atattgccat tggatttgta gatacattaa aaatgttttt tggcgataat
    10441 ttaaattgtc atgtggtaac acttggagat gcaggcattg aagaattccg tgaaaacatt
    10501 gaaaaaatag tttctcaagt aaaaaatcaa gaagttatgg tatttgctga cttgattggt
    10561 ggaacacctt tcaacgaatt tgctaaaaga agtgaagtat ttcaaaatgg gtttcaactt
    10621 cttggtggca tgaatttagg aattttgatt gaggctgtca atttgagatt acaaggaaaa
    10681 aaaagcgatg atatcatcga aaatctaaga aatatgaata caattgcgtg tcttgcagat
    10741 atgcaaagac atactaacga agaggatgag tgataaatgc aaaaaatttt ttacaagcct
    10801 aaagattttt ggtttgggga ttgcatgcct ttttataaag atggaacttt ttatctattt
    10861 catcaacgag atacgagaaa tcctaaacct ttaactgatc cttttgggtg gtcactagtt
    10921 acaaccactg attttgtgaa atttgaagaa tacggggaag taattcatcg tggtggcaac
    10981 gatgacattg atcaatacat ttacgctgga agtattgtcc aaggaatcaa tgagtattta
    11041 gctttgtata ctggacataa tcgcaaagct aagttggatg gaaaaacttc agaagtgtta
    11101 atgattgcaa gttctaaaga tttaattcat tggaaaaagg atggcgaagc agcaaaactt
    11161 gttcctcaag aaggatatga taagaatgat tggcgcgatc cttttgcaat ttttgatcaa
    11221 gatcatggaa aatacgtttt gatactagga gctagaaaac cagcaagtaa gaaaaagccg
    11281 acggggagat tggtctattt tgaatccgaa gatttaaaag attggaattt caaaggagac
    11341 tactgggcta ataatgaatt taacatgatt gaaatgcctg atatatttga aattgatgga
    11401 acgtggtatt tacttttttc agagtattgt gaagataaaa agactaaata tcgagtcgga
    11461 gcaggattat tttcagattg gaaatcacca gtagacgaag ctttcgacgg aaaagcctat
    11521 tatgcagcaa gaacagtcgg aactaatgaa actggccgtt ttctaactgg ctgggtggca
    11581 acaaaagaag gggagaacga tcaaaataac tgggattggg gcggtgcact tgttccacat
    11641 caaattattc aaaagacaga caaaactctt ggtgttaaac tgcctgaaaa aataattgag
    11701 aattttaaag aaatcactcc attttcaagt tttaagttag agaaagaatt tggaaaaaaa
    11761 gaaagagtaa ttgttcctaa aatcgaagat tattttctat ttgaaacaac tttgactatt
    11821 acatcgttaa caaaggagtt tgctttaaaa ttatttgtag atagtgatac tcaagaagga
    11881 tacgaatttc gtatttcatt gattaataat cagcttactt tcggaaaaac tccgaactat
    11941 ccttggcctc aaatgtttga taaggggctg caacgaccac tatttttgga aataggcaaa
    12001 gaatatgaac taaagttaat tgttgatgat acgatagctg ttttatatat tgataatgtt
    12061 gctttaagta ctagaatgta tgataaagtc ggaacagcat taagtatgac tgttacggag
    12121 ggagcaatca aggtagataa actagactat tcaataaatt atgaatgtgg attttaaaac
    12181 aattgaaggg atgatgtaag tgaaattaaa tggtttacaa catattggaa ttccaacaaa
    12241 agattttgga gcttcaaaaa tcttttatga atccttaggg tttagtctga ttaatgaaga
    12301 aatgaatgtg ggaagtaaag tcggcttttt cgagttgaat ggaacgataa tagaaatatg
    12361 ggaagataaa actactgagt gtagaggagc cattgatcat ctagcattag atacggatga
    12421 catagatgag gtattcaatt caattcaaga tttaggatat gaattattag ataaaaatat
    12481 tatggaatta ccgttctggg aaaatggaat ccgttacttt aatttctacg gaccaaatca
    12541 tgagattata gagataagcc aaatgaagaa ataaatagat aacgaagtgc tctaagttgg
    12601 tatgaacgaa aagtacttca ttttttggta tcagcatttc aatagtttaa tgagaattta
    12661 ctatttcaaa ttaattcaaa gtgacagtat tttttactta tttggtttca aattttgtaa
    12721 tccttcctat ttattggaat acactccaca ttttgtatac aagtcatatc atgttttagc
    12781 aaagctctta ccaagcaaag ttataatgat gttttccaaa gtttgatctt tcgatggagg
    12841 ctaacacata ttttttgcag gacagccaaa attagatgta tagaatagag tctgtgaggc
    12901 gtatagacag tttattgtct gtatgccttt ttttattttg aaaaattttt agtatttttc
    12961 gaaaaatgct cactcctag
//
LOCUS       DAFTHM010000075        12718 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFTHM010000075 DAFTHM010000000
VERSION     DAFTHM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.075"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(69..248)
                     /gene="rpmF"
                     /locus_tag="L7C88_002044"
     CDS             complement(69..248)
                     /gene="rpmF"
                     /locus_tag="L7C88_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBP9558853.1"
                     /translation="MAVLARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(306..875)
                     /locus_tag="L7C88_002045"
     CDS             complement(306..875)
                     /locus_tag="L7C88_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBP9558854.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1061..1963
                     /locus_tag="L7C88_002046"
     CDS             1061..1963
                     /locus_tag="L7C88_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBP9558855.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(1998..3782)
                     /gene="pyk"
                     /locus_tag="L7C88_002047"
     CDS             complement(1998..3782)
                     /gene="pyk"
                     /locus_tag="L7C88_002047"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBP9558856.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3856..4818)
                     /gene="pfkA"
                     /locus_tag="L7C88_002048"
     CDS             complement(3856..4818)
                     /gene="pfkA"
                     /locus_tag="L7C88_002048"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBP9558857.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(4986..8300)
                     /gene="dnaE"
                     /locus_tag="L7C88_002049"
     CDS             complement(4986..8300)
                     /gene="dnaE"
                     /locus_tag="L7C88_002049"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBP9558858.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8531..8716
                     /locus_tag="L7C88_002050"
     CDS             8531..8716
                     /locus_tag="L7C88_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBP9558859.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8778..9974)
                     /locus_tag="L7C88_002051"
     CDS             complement(8778..9974)
                     /locus_tag="L7C88_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBP9558860.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVARAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10144..11580)
                     /locus_tag="L7C88_002052"
     CDS             complement(10144..11580)
                     /locus_tag="L7C88_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBP9558861.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11873..12682
                     /locus_tag="L7C88_002053"
     CDS             11873..12682
                     /locus_tag="L7C88_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBP9558862.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3798 a         2672 c         2248 g         4000 t
ORIGIN      
        1 ctacaaaaaa ataaacctca aggctccatg gttagccttg aggttttaca ttttctaatt
       61 aaaatgtatt aagcttcttt tgacattacg tccttaccat catagtaacc acaatttgca
      121 catacgtgat ggcttttttt catttcacca cagtttggac attcgtttaa ccctttgatt
      181 gtcaatttgt agtgtgtacg acgttttgct tttttagctt ttgatgttct tctagctagt
      241 actgccattt tgctacacct ccttgtaaag tcttgtatct aaattagaca caatatattc
      301 caatcttact tgttatcgtc gtcttttgat ttagaatcaa aaagttcaga tagttttgca
      361 agacgaggat caattttatt ctcggcttct tccatttttc tgcgctggta ttcttcttcg
      421 gaaacaactt cccaatcatt gccttttgga agttctgttg ctgcttcctc ttcttttgtc
      481 aatacccgca ttggaatcgc caataagatg ttgtcttcaa tcgactctgc taaattcaat
      541 aatggacctt caattagcaa aatctcatct gcagacattt gttcatctct actttggaat
      601 tgttcttctg tcatgaatac ttcgtctaca gaaaaatcca tgggcagttc aacaggttct
      661 agtgaacgtg ttgaaggaac tgtcaaagtc gtctgcacag tgtaatgaac gatatagcct
      721 ttcttatcaa ctgagaccaa accttcgact tccactggcg caacatcaag tattaaattg
      781 tctcgcttca tgagagcggc tttcaagtcg agcgtctcat gaaaagttaa cggtgtctcc
      841 tggtattttc tcaattccaa taaagaccat ttcatttttc atcactccta agcaacaaaa
      901 gcaattatac agggcaaaaa gcatgttgtc aatgaaattt tcttgacacc ttgcagttca
      961 taaaaaaaca gaaaaatctt tattagaaag cctctgtttg ctatcatcct cagaatcatt
     1021 tacaataatc attattccat taaaggagcg gatgatcttc atgaacacga aagatatcga
     1081 atactatgtc caaatcgtca aacaaaaaaa ttttacgaaa gtggctaatt atttccgtgt
     1141 gagccaacct actattacat atgcattaca acgtcttgaa aaagagtttg acaccgtact
     1201 tattacaaga gatcgatcgc atcacgaatt aatcgtcacg ccttctggaa agcagctgtt
     1261 tctccatgca caaaccattc tccaagagat ttctactgca agagctgaaa tcactcagtt
     1321 gcaaaagaaa aagcttcgtt ttggcatgcc tcctattatc ggcaatgaat actttcctaa
     1381 actgtcaagt tactttatca agcatgaatt gatgaatcaa attgagatta ccgatggagg
     1441 ctctcgggac ttatacggga tgatccgaca agggaggatc gatttagctg tattaggctc
     1501 aacacagcca atcgtggatc aatatttaga aacagagtta cttttggaca aacgtttcat
     1561 gatcgtcgtg ccacctacac atcctctttc caagcaggat actgtctctt tcaaagatat
     1621 agcagatgaa cagtttgtac tattgaacga acattatgtc caccccgcag cattcactaa
     1681 gctttctaaa caaacacata ctcatccaaa agttgtttat caaagcaatg acttgacgat
     1741 tttaaagagt atggtccgag aaaatgtggg tatcggtttt ttggcagaga ttgctgtcca
     1801 tcctgaagat catttagttt gcctccctct ttcagatgaa gttcagcctc gcttcttgat
     1861 ttcattggca aaacgaacac agcagatcgt cacgcctctt caagaacaag tagtccaagt
     1921 tatccatgaa ttcgttacag cacaaaaaaa cagctcttcg taaaagaaga gctgttttta
     1981 ttttttatta agctaaatta gatagctgtt gtttcgccac ggtaaacgat gccgcgacgt
     2041 gaatcaacgg taatcaattc accttctgta attgttgttg ttgcgccttt agcaccaacg
     2101 attacaggaa tatcttgtgc aattcctaca actgcagcgt gagaagtcaa tccgccttct
     2161 tcaacgataa cagcagctgc tttttcgatt gcaggcatat attctttgtc agttgatggt
     2221 acaactagaa ccattccgtc ttttgctttt tttacagctt cttcagcaga tgaagcaata
     2281 actgcatttg caacgacaga tttttgtcca acgccttgag cttctaataa tttagaacca
     2341 atcatttgaa ttttcatcac gttagttgtt ccgcgttcac caactggtac accagcagtg
     2401 atcaagatta aatcgccttc tgatgcgaaa cctaattcaa cagctttttt agctgctagt
     2461 tcaaacattt catcagttgt tgatggtttt tcagcaactg ttgggtaaac gccccagttt
     2521 aacatcaaac cacgttttgt gcgttcgtca aaagtaacag ccaagatatc tgcatctgga
     2581 cgatattttg aaatcatttt tgcagtgtat cctgattcag ttgcagcaac gattgttttc
     2641 acgcctagat tttttgcagc acgagctaca gataaaccga ttgtttcagt tacatctgtt
     2701 ttatcgaatt cgttcaattg gaatgtacct aattctgata atgcattttc agcttcttgg
     2761 tcgatacgtg ccattgttga aacagcttca actgggtagt ccccgtttgc agattcacca
     2821 gatagcattg ttgcatctgt gccatcaaat acagcgttag caacgtcaga agcttccgca
     2881 cgtgttggac gtgggttttc ttgcattgat tctaacattt gtgtagcagt gataactggg
     2941 ataccagcag cattacattt tttgataatg cgtttttgaa ccattggtac tagttcagct
     3001 gggatttcaa cacccatatc tccgcgggca atcataacac cgtcagaaac tttgatgatt
     3061 tcgtcaatgt tgtcgatacc ttcttgagat tcgattttag ggaagatttg aacatgagtc
     3121 atgtcttttt cttctaagat ttcgcggata tctagaacgt cttgtgcttt acgtacaaaa
     3181 cttgcagcga taaagtcgat atcgttgtct aaaccaaaac gaatatcgtc agcatctttt
     3241 ggagtaatac ctggcaaact aatagaaacg cctggtgcat ttaccccttt acgtgatcct
     3301 agcatacctg catttttaac ttctacgact aattcacggt ttgcttcgtc tttttcaatg
     3361 atttgcatat cgatcaaacc atcatcaaat aaaatgtgtc cgccaacgtg aacatcgtca
     3421 aataatcctg ggtaagtaac cgcgattttt tcttttgaac ctacatgttc aggatccata
     3481 gagatgcgtg tttgatctcc tacttcaaat ttgatgtatc ctgcacgacc aaaatcagct
     3541 tctgttgtgc cttgaacagt tgtacggatt tcagctcctt ttgtatctaa aagaataccg
     3601 acatcttttc ctgtcttttt aactgcttca cggaccatag tcatacgtga taattgttct
     3661 tcatggtcac catgagaaaa attaaagcgg aagacatttg ccccagattc aatcaattga
     3721 gaaataattt ctactgagtt acttgctggt cctaatgtac taacgatttt ggtttttttc
     3781 atttaaaaaa ctctcccatt caattttgtt tatttaaagc tgtacacagc ttaaatagct
     3841 tggtttcttt cactcttaaa atgaaagtga attatttaga tcatatagtg ataagtctgg
     3901 tttatgtttg ttgttttcaa gtgtatcaat gatgtcagac gcaacgattt cgttgtcatg
     3961 gataccgaca cataatccac cttttccttc ttgaagcaat tcgacagcgt aagcaccgaa
     4021 tttacttgcc aacacgcggt cgcgtgcgct tggtgctcca ccacggacaa cgtgtcccaa
     4081 gatagataca cgtgtatgat agtcaccaaa ttctgaaagt ttctcagcga attcatttcc
     4141 gcccattaca ccttcagcca agatgatcaa gcaatgtttc ttcccgcgat cgcggccttc
     4201 ttggattttt ttagcaactg aagccatatc aaaatcatgt tctgggatga tgatttcatc
     4261 cgctccgcca gccacacctg accataaagc gatgtctcct gcattgcgtc ccattacttc
     4321 gataacgaat gtacgaacat gagaagtcgc tgtgtcacga atacggtcaa ttgattctag
     4381 tactgtattg attgctgtat caaaaccgat tgtgaaatca gtcccaggaa tatcattatc
     4441 gattgttcca ggaataccta ctgctgggaa accgcgtttt gtcaaagcca ttgcgccatg
     4501 ataagagccg tctcctccga taaccactag accttcgatt ccgaattttt tcaattgttc
     4561 gattcctttt aattgacctt cttcagttgc aaattctgga taacgtgcag aatacaagaa
     4621 tgtaccacca cgttggatct tgtcacctac atctgccaca tcaagacgac gaatatctcc
     4681 agcaactaaa ccggcaaaac cataattgat cccgtatact tccagtcctt cgtaaatacc
     4741 tttacgaaca acggcacgaa cagctgcatt cattccaggt gcgtctccgc cactggtcaa
     4801 aattccgatg cgtttcataa taaacattca cctcattaaa atactttatc ctaagtatga
     4861 cttaggttta caaccatttt tgcgttaacc acgactaaca ttctaacatt atttttctca
     4921 cttgtcttga tttacggata aaaaaatgaa aaaaaatgaa agcaagtagt attttttacc
     4981 gtaagttatt tgaaaaccac attatcttcg ccaagcagat aaataagttg cccctttata
     5041 ctcttgctgt catccaccca ataagcatct gacagaacta cttttcgttg cgttttttcg
     5101 tgatacataa ctactggtat atatcctggg tgtttctgaa aaatcacttg taattgtttc
     5161 attatctcgg gatcttcccg ttcttctgta atacgcaaat agcaagtttg tgaaggatac
     5221 tgggcttcta actggttagg atcagcaaag ctttctccaa ttagttgcag ttcctgatta
     5281 tatttgctga tttcgctccg cccttgaaca aagatcactc gatcaacggc aaacaaatta
     5341 cgatatttac gataaagagt tggaaaaact gtgacagaaa tttctccact actgtcggtt
     5401 ccttcaacaa aggccatcag ttctcctttt tttgtccgaa tttctctaac ttccttgatc
     5461 atcactaata aattgactgg ttgattaggg acgatatctg taatcagctg aacttgttta
     5521 gctaaacgaa gacgatcaaa cccttctgca ggatgacctg acaaataaat acctaagtac
     5581 tcctcttcca gcttcaagcg ttcttctagt gtatagtcag cgacttcttc ttcttttaat
     5641 gccatgattc ccagcaagtc aagacttcca ccactgtaaa cgatattttg gatttttcct
     5701 tcgagatcaa gcatcaattg tttcctgtta ggagataatt catcaaaaac tcctactgct
     5761 gtcagtgatt gcagtaactc taatttcagc caacgcttat cgatccgtat gaggaattga
     5821 tccactgact ggaacgggcc attttgtttt ctttcgttta atatatcttc tacaaaatca
     5881 cgccgaatac cttttatcgc tgtcagtccg aatctgattt cttccttatt gaccaactca
     5941 aaactggaat tactttgatt aatggacggc gaggaaagtt tgagtttatt tttacgtgct
     6001 tctgcaatat attctttcaa ttttgatgtg ttatgccgaa cagaattcat caggctggta
     6061 aagaaagcac ctggatgatg ggcttttaga tacgccattt ggaatcccac gaatgaataa
     6121 gcaaatgcat gtgaccgatt gaatccatag tttgcaaatt tttcgatata ttcatatacg
     6181 gtcgctgctg ttttttccga atatccctgt tgtaatgctc ctgatacaaa atgcgacttt
     6241 tcttcatcta atacgtcttt tttcttttta ctcactgccc gtcgcagaat atctgactgc
     6301 cctaatgtaa atccagccat agtcgaggcg atctgcatga tttgttcctg atagacgatc
     6361 actccatatg tgtttttcaa aatcgggatc agtgaatcat ctgggtagcg aatggcttct
     6421 tttcctttct tcctggcaat gaaggtatct atattttgca tagggcctgg tcgatacaat
     6481 gcattgactg cggcaatatc ttcgatgttt tctggatcta atcttcgtaa aacgttccgg
     6541 ataccagcag attcaaattg aaatactcct gaggtttcgc ctcgttgaaa caagagcagc
     6601 gtttttgcat catttagcgg gatctctttt aatcggatct catacccttc tactcgctta
     6661 acagctttca aagtaaaatc aataatcgat aagttgcgta gtcctaaaaa gtccattttc
     6721 aaaagaccga ttgcttctac ctcattcatc gtatactggg tcagaaaagc ttcatcagaa
     6781 ccgcgttgga gcggaactag ttcaagtaga ttcttatcgc tgataactac acctgctgcg
     6841 tgagtcgaaa catgtcttgg caatccttct aaaatcactg cagttttgaa taaaagttgg
     6901 tttttttcgc ttgcctgaac taattctact aattgatgcg aagttttata agcttgggtc
     6961 aatgtgattt tcaattgatt gggtattgct tttgaccagc ggtttgcttc actttgcgat
     7021 aaaccaaaca ctctagctgc atctctaaga accatttttg ctgccattgt gccaaatgtt
     7081 gcgatttgtg ccatatgata ttgtccatac ttttctcgaa cataattcaa tacttcttca
     7141 cgtcgattgt caggaatatc caaatcgata tctggcatcg taaagcgttc ggggtttaaa
     7201 aagcgttcga acagcaaatc atattctaat ggatccacat ctgtgatttc taacacatag
     7261 gctactaatg aacccgcagc agaaccacga cctgcaccgg taacgatttt gtttctatga
     7321 gcaaaagcca ttacatccca tacgatcaag aaataatcat cgaatcccat ttgatggatg
     7381 acagataact cgtagtccaa acgttcttgg tattcctttg tatagtcagt gattcggcgt
     7441 tccacttgcg aatagcataa ctctcttaaa tattctccag cttgttttcc attaggaact
     7501 ggataatgcg gaagtaattt ctgatggaac tggaattcaa atgaaatcga ttcagctaaa
     7561 cgctgggcgc ctattacagc ttgggaaaga cccgcttttt cgaatcgttt gatcatttct
     7621 tgttctgaaa gaagatagac atttgctgtt agtggtaaag atgcagataa attttctaaa
     7681 ggtatttggc ttccctcttt gatatgtttc atcacttcaa gtgcaaaaag ttcttcttgt
     7741 tgtaaactag cgatgggatg taatgcacaa agcgaataat tttcttttat cacatactga
     7801 taccattcag gcaattgatc aggcgtgttt tctgtcaagc cgatataaaa atttctagta
     7861 aaaacatttt caagtaaaaa ctgccaatga ccgaaaaagt tatcctcttt attgaaagcc
     7921 tcagaaacag aatgatttgc cggaacaaca aacgctagat ggtcggtttc tgtcatttct
     7981 gcaagttcca atttttcttg gatcattttt cggctggaaa gtttcatcag ctgctgataa
     8041 cctatttcat cttttgcgta cgcaagcaag ccataatttt tttcttcata agtataacta
     8101 agatgtaatc caatgattgg ctgtactcct tcttctacac aaatacgata gaattcaggt
     8161 gcaccgtata agacatcttt atccgttatg gctaatgaag tgtagccttg tttttttgct
     8221 tcttgtacat attctcgaat acgtatcgta ctttgtaaaa gagaataaga agtaattgta
     8281 taaagttgtg ggaaaaacat cttgcattcc gccttttttt tcgttaaaat tcactagcgt
     8341 taaaaggttt gatcctttta ctttcattaa gatagcaggc gctgaagttg attattccac
     8401 ttcatttgct tgcttgtaat ctgtaggaat gagttctttc gcaagaactc aaattttatt
     8461 gagatttggt ctcgtttctt tacattcaaa gaaaatctgg taaaattaag atagaaaaga
     8521 ggtgttcttt atgcgatata tcgttacatt attctgggct gtcgttctag gtcaagtagt
     8581 cggttatatt ggtgctgcat taacaagcgg aacatatgat tttactttga caacaatcat
     8641 ttcattcatt gcgggtgtca ttatcctttt gattggtgca gttgcgccaa gaaaagaaac
     8701 ctctgcccat tcgtaaaaaa acagccaaga gcttgagatt tctcaagctc ttttttattt
     8761 tctactcctc accaccatta taatctgctg cgaagaactt tacgaaagtt gaataaagaa
     8821 agaagaatat ttgacagaac aaacaaactt gtcacaataa aaacagcact gtaattataa
     8881 gcacgcgcga ctgtcgatcc tagcatggga cctaaaactt gtccaaagtt gctaaacatc
     8941 tgattgtagc tatagattcg gctgactcct tcttgaggcg taatcttact gatcagtgta
     9001 ttgacagaag gcatcaaagc gccagttgaa aagcctaaaa taaagcgaag tatacctaat
     9061 tggagcggtg tagtgacgaa tgccataggt aaataacagc aaaatgataa aatgagtcct
     9121 ccaattagaa ctttttgatt cccaatctta tcccctagtt ttcctagttt cggtgaagaa
     9181 aagacagcgg aaacaccagc tatcgaaaca atcaagccgc tgacaaaaag gatattttct
     9241 gtacttccgc tcaattcacg aatatataag gtcaaaatag ggctgatcgt agtgattcct
     9301 atctgtaaaa tcaaggtcgt aatgaagaga ccgatcaaaa tagagagatg atccattttt
     9361 gaaaaaattt ctttggtgct tatcagatct tttttctcga ttggatggaa atcttctttg
     9421 actaagaaaa tggtcaatac cgttgtgatc atcaacaaag cccctgtgat caagaataca
     9481 ttttccatac caaaccactg agccagtgca ccgcccattg aaggtccgat cagatttcca
     9541 gcaatcgctc cggtagacaa tgttcctaac gcccatccgc tcttttctct aggtgcctgt
     9601 gaagcaatca tcgctgtggc atttggaata tatccagaca aaatcccatt ccaaaaccgc
     9661 atgatcaaaa gccaatacgc gtttggtaca aaagccaaag atcccattgt taatgtcatc
     9721 cctgctgctg cacggatcat catgagtttt cggccttttc gatcagctag atttccccag
     9781 attggtgcaa ccacggcaga tgcaaaagca gtcacagaga ttgctagtcc cgaaaacaat
     9841 tcgatttgat cttttggtgt tcctagttgc tcaacataaa ctggtatgaa tggcataact
     9901 aaactaatac ttgcaccagt gaaaaaacag ccaatccacg caatcactaa attttttctc
     9961 caattaatct ccatctatca tccctctttc gtctctttta tcatacctat tttcgaataa
    10021 acaagcaacg atctcgccag taaaaagaga aaaatcccgc aaaggtcatt ttatatgtaa
    10081 cgttcttttt atgtaaaaca aaaagagatc agaacaatta ctgttccaat cccttctctt
    10141 tagttaaatt gttgctagaa tgatgaagtt gataatgaat aaaatatcaa cgatccacaa
    10201 agcaacagaa acttgattgt attttccttt gattactttc acaattgtat agaaaataaa
    10261 tcctgctgca atcccatagg aaatgctata gcacaatccc ataaagatcg atgcaaagaa
    10321 ggccggtaaa gcttcttcca tatctagcca tttgatgtct gcaaaagaag ccatcatcat
    10381 tactccaact aaaatcaatg ctggcgcagt tgcttgattt ggtacaatgg cgatcagtgg
    10441 agagaataaa ctacttaatg cgaatagcac tgccactact actgaagtca aaccagtacg
    10501 tccaccggcc ccgatcccag ctgcagattc gacataagtt gttgtattcg atgtaccaaa
    10561 gatagccccc acagaagtag cgatcgcatc ggcaaatagt gctttatcca tttttgtttt
    10621 gaacccacga ccatcttcca acgcgatctc gtcttctttt gagaaaatac ctgtgcggcg
    10681 tcctgtaccg ataaatgttc cgatcgtatc gaaagtatca gataaactga atgcgatgat
    10741 cgtcatcaat acttgaggaa tcttggaaga atcactgaat aaagattgca tgccttcaga
    10801 accaaatgct gcaccgaaag ttgttcctaa ttctttaaat gaattaccta acgaattcgt
    10861 ttgccaatca atggaactta aatcaacaac acccataaaa ataccaagga ctgtggtcgc
    10921 tacgataccg ataagaatag ccccacggac attttttaca actaaaatgg ctgtcagtac
    10981 caaaccaatc acagccaata agataggagc gttgtcaaag ttggctaacg cagggacgat
    11041 tccaccattt atcgtaacat ttgtcgcttt tccgccttca acgacagagc tcgaaatagc
    11101 tgactggtct gctgaaaaag ataagaatcc tgcatttttg attccgacat acgcaacgaa
    11161 aataccgatc ccgccaccaa tcgcatgttg aagactttcg ggaatcgccc gaataatcat
    11221 ttttcgaata tttgtgacag taataaaaat attgattaat ccgcaaataa acaccattgc
    11281 caaggcttgt tgccaagaat aaccaagccc aaaaacgacc gtaaaagtga aaaatgcgtt
    11341 caatcccata ccaggtgcct gagcatatgg tacatttgcg aacaatccca ttaccagcgt
    11401 accaataatc gatgcaatga ttgtcgctag aaatactgct tggaagggca tacctgatgc
    11461 tgacaaaatc gtcggattta cgaataagat ataactcatg gcaaagaatg tcgttactcc
    11521 cgccattatt tcagttgata catttgtatt gtttttcttt aaaccgaaaa acttttccat
    11581 aaaaagttcc actccctgaa tttttttctg atggaaaact ataataataa aaaataagta
    11641 aaatagggca aatccatcga acaatttcaa attatataga cgtttcattc gcttttcaac
    11701 gtttttttaa caaaaaaagc gaaaataata cttaacgttc gtgtttagct tatgtttagc
    11761 tatttatata gccataactg tagtttttgt taggaatagc tgattgctct tgttaattac
    11821 ctaaaatatg ctagactaaa acaaatgcta gttgaggaag gaaggaccct tattgaataa
    11881 aaaattaatt gccatcgatc tggacggaac taccctcaat caagattcga tgattacatc
    11941 taaaacaaaa gagactctaa aaaaagcaat caatgccggt catcatgtca gtattgctac
    12001 aggacgccca ttccgaatga gccatcagtt ttaccaacaa ttagaattaa caacaccgat
    12061 ggttaatttt aacggcgcat tagtacacat ccctaatcag cactgggatg gtgaaagaga
    12121 aacgttgatc aatcgtgaaa tcgcttttga aatcttatcg caaaaaaagc agctaaattt
    12181 agattttatc gctgctgaaa atcgtgatac tttttttatt gacagttttg atttctttga
    12241 tgaaaaaatt tttgcttctt ctcgtccagg agagaagaat ttgctttctc ctaaaaattt
    12301 gacgacaaat cctacatctt tgcttgtccg aacagacaaa cgttttgcag gagctgtatc
    12361 tgctgaatta acacgtcaat ttggcagtta tgtcgatgtt cggacatggg gtggacctac
    12421 tgccatctta gagattgttt caaaaggaat ccaaaaagca aaaggcgtgc aagagattgc
    12481 taactacctg tctatcgatc aaaaagacgt cattgccttt ggtgacgagc ataatgattt
    12541 ggaattgttg gattatgcag gttggggagt agctatggct aacggtactg accaactcaa
    12601 aggcattgca aatgatgtca ctcctttgag caatcaggaa gacggtttag ctgtttatct
    12661 ggaaaaacta cttaaactat aatagagaat tagattccac aaaaaagagg ttgtgaca
//
LOCUS       DAFTHM010000076        12625 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFTHM010000076 DAFTHM010000000
VERSION     DAFTHM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.076"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..164
                     /locus_tag="L7C88_002054"
     CDS             <1..164
                     /locus_tag="L7C88_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBP9558863.1"
                     /translation="IALDYREAFGTIKQDQLQGEGFMQDNISYQKVSDQELDRVKKEL
                     KDQMNLENK"
     gene            180..959
                     /locus_tag="L7C88_002055"
     CDS             180..959
                     /locus_tag="L7C88_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBP9558864.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            971..1669
                     /locus_tag="L7C88_002056"
     CDS             971..1669
                     /locus_tag="L7C88_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBP9558865.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            1697..2461
                     /locus_tag="L7C88_002057"
     CDS             1697..2461
                     /locus_tag="L7C88_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBP9558866.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKIPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFG
                     KEKVVQMKQVAKDLINGDEINYPIYEEVKKKKFGLF"
     gene            2505..3956
                     /locus_tag="L7C88_002058"
     CDS             2505..3956
                     /locus_tag="L7C88_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBP9558867.1"
                     /translation="MYRKNSSGWSKHIDFILLDLFCVQLAFYISYVMRQGDWNPYVIP
                     IYRHMAIFIELENLTIIFLFEAYKNVLKRGYYKEAVASIKQSFMLLLVCSLYLITMQD
                     GNDYSRVSLFIMGVVYGLLTYIIRILWKGLLHHRMKNGEDVSLVIVTSQKIAKNVVRN
                     LKEKNYGMYKLSGVIVVDRDMYGTTIGGVPVVANADNAAEYLLQNWVDEVFINVDESV
                     PYPKELIARCSEMGLAVHMNLTKVSDSTRGKQFIGRVGDYTVITSSINVMTMRQAFIK
                     RTIDILAGIIGCIATGVIFIFVAPVIYIKSPGPIFFAQERIGQNGKTFKMYKFRSMYM
                     DAEERKAELMKENKMSNNLMFKMDFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FYNVLMGKMSLVGFRPCLKSEYEKYDFHHRARIAMKPGITGMWQVSGRSDITDFEEVV
                     KLDAEYIRNWSMGLDFRILFRTVKTVLHRNGSM"
     gene            3988..5124
                     /locus_tag="L7C88_002059"
     CDS             3988..5124
                     /locus_tag="L7C88_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBP9558868.1"
                     /translation="MARKKLKICMLGHKRIPSREGGIEIVVEELATRMVALGHEVTCY
                     NRSGHHVSGKEFDQHKNKEYKGVKLKTIFTLNIKGIAAMSSSVFGGIRAAFGKYDVVH
                     FHAEGPCAMLWLPKLFGKRCVATIHGLDHQREKWNKLASTYIMLGEKCAVKFADEIIV
                     LSESVQNYFEDIYGRKTRFIPNGVKKIEIKSAGLITEKYGLTKDSYILFLGRLVPEKG
                     IRYLIEAFKDVQTDKKLIIAGGSSDTDEFANELKELAKGDERIIFTGFVQGQELEELY
                     SNAYIYTLPSDLEGMPLSLLEAMSYGNCCIVSNISECTEVVEDKAMIFKKSDVSDLKI
                     RLEEACNQSEMVKVLKNQATEFICSKYNWDKIVQETLNLYRGNI"
     gene            5124..6230
                     /locus_tag="L7C88_002060"
     CDS             5124..6230
                     /locus_tag="L7C88_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBP9558869.1"
                     /translation="MIRILQCVNDMHRAGLETMLMNYYRNIDRTKIQFDFLTHRPYKS
                     DYDEEIISLGGKVYYAPRLYPQNYPKYFKWMEQFFKDHPEYEIVHSHIDAMSYLPLKA
                     AKKAGIPIRIAHSHNTSIDRDFKYLLKQYYRCKLTSVLTHEFSCGKVAGDFLFRNDKF
                     TLIPNAVDAKKFYYDESIRNDVRMKLGISSQTFVMGHIGRISYSKNHRFLIEIFKEFH
                     AIKNNSVLLIIGTGDMEEEIKNYAKKSGIDDDIKFLGNRNDIEKFYQAFDVLMLPSLF
                     EGVPLVGIEAQFADLPCFFSEKVPTEVAFSDKTNFISLNQSAKEWAREIANVDISHRD
                     SERSILIKADYNIQTAYKILESKYYELFELIQRG"
     gene            6236..7258
                     /locus_tag="L7C88_002061"
     CDS             6236..7258
                     /locus_tag="L7C88_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
                     /protein_id="HBP9558870.1"
                     /translation="MTQKHSSIKRIIHRISEELNATRRIAKITSWKEAFATLQAKIDI
                     QVMNRNGYNESKKQKEHLLKKHEVMLKYYEKTFSDFLKTYDYSQNQIINQSKSPYSNC
                     IWVCWWQGLDQSPEIVKACVKSIKRNAGKHTVIILTEDNYRQYVDIPKWVEEKKNKGI
                     ITRTNYSDLLRLSLLAKHGGLWLDATFYCTKPIPDEYFDIDIWSIRRPDYAHASVASG
                     YFAGYSLACNQESRWMFAIIRDFFLNYWKNNDMMVDYLMIDYMIVLAQRINHEIAQTF
                     DKIPSNNPLCDELIKNLNNIYDEKVWNLLKKDTLLFKLTWKQSFKKQKDDKVTFYGML
                     VENKLL"
     gene            7280..8335
                     /locus_tag="L7C88_002062"
     CDS             7280..8335
                     /locus_tag="L7C88_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBP9558871.1"
                     /translation="MKHKVSVIVPIYNVEKYLRKCVDSLLSQTLKEIEIVLVDDGSPD
                     ASGEIADEYQKKYSNVKTIHRENGGLGPARNTGIENATGEYVAFLDSDDWVESDMYEK
                     LYLVASKENADIVVSGHCDFANDKAMVKKQHPLSGNVYDTPNSIKNVRKNLFGHSPKD
                     QEVEAFPMSVCMSLYNKNLLDKYRLRFEKILSEDTIFNLNAYDVANKIAFTEYTDYCY
                     RKEEQESITKSLSPNKQTEFKEFLITLKAIASKEDLECQIRAKRMAIDYCRLYVGLVD
                     DANLGIKEKRKYIKKFIEDEGLIQCWKGYPTNTLPFQQKFFHKMLECKCYTILLLLSR
                     IRKIIKNMTRKKLFIIL"
     gene            8953..10188
                     /locus_tag="L7C88_002063"
     CDS             8953..10188
                     /locus_tag="L7C88_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558872.1"
                     /translation="MSVKKMLFMVSTIIVLTSRFWGINTSLSMRYFIMAIWDLYFMLS
                     YFSYREKTYKKYVIKNNFWLTIMPFVIFSIYTLIIWGIGSNAEFENFIKLCSTLLYLI
                     LAYGYACTAFYLFKAEGIDFIFWSGVISYMSGSVFYLIVSYGLNGLISYIKSLITGET
                     NTANFAMEVHDLTFAMGVFFLYYVFFENKNTKKHKIKIIVSLILIFMGLKRIELLALS
                     GAILVYYVLLKWGKKIQIRALVCTICATVISLVFIYIIDTGILALLMSNLGITDDGAR
                     LSFYLYSSKFYELGLGYVGTGWTWFSKYFFNLYLSHFRLNGGRIAASLHSDILTIYIE
                     VGCIVFIIWMFWLFFVKPIRLTKKFGLKTGECVLLLTIYMFILYLTDNTLTYPDTQMI
                     FLLVPMIVSWVDNQQRISE"
     gene            10272..11360
                     /locus_tag="L7C88_002064"
     CDS             10272..11360
                     /locus_tag="L7C88_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558873.1"
                     /translation="MKKILVLANTYYQIIVAIQMKNTIFSDEYVEIIISDHSKNTKEI
                     AKKIEEKKVFDGCHYLESKSFDDNIGYFQKIKDCLQISCGKSNRYAYYLKNCKSEYFD
                     EFICFSMGEVWLEGIYACLYRNNKNVQVSILEEGILSYGVDIIPTARTKAIAVLNYLK
                     KRTPLYNKSYNFYCFFPNIYTGRENTIQIPLVTAGSRTALQLSDIFNPMIDIYKEKKY
                     IFFTSVYDFEGGEPVGEYELVCKIADLVGKDNLIVKTHPRDVRTIYKDNGFIEDKNSS
                     IPWEAIQLSGDFNDKIFMTINSGSVISGSTMSAKPVRTYYMYKLCNIEGNPSCKKNAY
                     DIERLLKQKTMKNILKNVKIAESLDDIL"
     gene            11357..>12625
                     /locus_tag="L7C88_002065"
     CDS             11357..>12625
                     /locus_tag="L7C88_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBP9558874.1"
                     /translation="MSKTKYLIKNMGILTISNFSSKILVFLLVPLYTSVLSTTEYGTY
                     DLTISTATLLFPILTLNIVDAVMRFLMDKDKNKKNIASIAIKVIFLSVIVFGSVMYLL
                     NITKLWQDVYGLEKYIFLYYISYVWNQFLIQFAKGLEKVKAMGIAGIISTIVTIIANI
                     FFLLILKWGLIGFFIANILSQIISATYLSVLVRIWEYIDFEAKDPQLKREMLNYSIPL
                     IATVVGWWINSTADRYVVSFIVGVSANGLLSVAYKIPQIINTLQGIFIQAWQISAIKE
                     YGDNETAKFYGNTFVMINLLMCITCSSLIILTRPFSHILYAKDFYEAWKYVPFLLIAN
                     VLNCASGLLGPILSAKKDSKSMMWSAIIGALVNVIMSVVLVYKIGVQGATIATVICSY
                     VIYVVRKRAVGKDIFIKHYHIVVESWGLLFV"
BASE COUNT         4595 a         1584 c         2463 g         3983 t
ORIGIN      
        1 aaattgcttt agattatcgg gaggcatttg gtacgattaa gcaagatcag ctgcaaggag
       61 aaggcttcat gcaagataat atctcctatc aaaaagtcag tgatcaagaa cttgatcgtg
      121 tgaaaaaaga attaaaagat caaatgaatc tagagaataa ataggaaagt ggagaaaaaa
      181 tggaagagac aatcagcttg aaagaaattt ttgaaacatt acgcaaacac ttggtaataa
      241 tcatcatctc aatgtttgct ggcttggcca tctcaggaat cgtaacattt ttcatcttga
      301 caccaaaata cagttcacaa gcacaattga tcgtgacact gccacaatca gacactgcaa
      361 atgtcaatga tgtcaatacg aacctgcaaa tgatcaatac gtataaagat atgatcgtca
      421 gtgatttagt gctcaatgaa gtcaaagatc gtttagaaac agaagacaat gtgaaaatga
      481 ctgctgaaca aatcaaagat gccatctcag ttaatcaggc agaaaattca caaatgttct
      541 cgattcaggc aataagtacg aatgcagtgg ctgctcaaca gatcgctaac acaacttcac
      601 aagttttcca agagaacgca aaagatgtga tgaatgttga taaaatctcg atcatttcag
      661 gtgcagttgc caatacgaca cctgtttcgc caaataataa attgaattta atgactggct
      721 taatgttagg aatgatggta ggtgtaggtc tggcattctt attggaatta ctcgatcgga
      781 cagtgaaaga tgaaaaatat gtgacagata cattaggatt cccaatctta ggaacagttc
      841 cagaaatgtc agcgaaagaa ttgaatgctg gtatccgtaa aaaaggacca gctcagacac
      901 aaccaaaagc tacaaacgat aaaacagcgc catcacgcag aagccgctca agagtctagg
      961 aggaaagaaa atggcacgaa cacagaaaca aaaagcagcc caaactcatg cagtcagttt
     1021 ggtcacactc accaatccct cttcaccaat cgctgaacaa tatcgtacga ttcggacgaa
     1081 tatccagttt gcctccgcag ctggtcagca aatcaaaacg attgttgtga cttcatcagg
     1141 acctggagaa gggaaatcga ccactgcagc aaacattgcc gttgtttttg ccaaatctgg
     1201 tcaacgggtg ctgctagtcg atgcagactt acgtaagccc gtcatctata aaacgttcaa
     1261 gttgaacaac gcaagcggat taagtactgt tcttagttca tcaggaagtg tagcagatga
     1321 gatccaacga acaccagtcg acaatttgtc gattctgcca agtggaccta aaccaccaaa
     1381 tccatcagaa ctactaagtt cgccaagaat ggatcagatt ttagcagaag caagacaact
     1441 atttgatgta gtgatcttcg acatgccgcc agtcgttgcc gtaacagatg cacagatcat
     1501 gtcttcaaaa acggatggca ccttattggt cgtacgggaa aatacgtcac gaaaagaatc
     1561 attgactaaa gcaaaagaac tgttagatat ggtacaagca cgagtcttag gtgtcgtata
     1621 caacggagca gaacacagca aagatgctgg ttattactac ggaaattaag gaataagaag
     1681 agaggagaca agagaaatga tcgatctaca ttgccatatc ctaccaggaa tcgatgacgg
     1741 ggcagaaaac ttagaagcaa gtattgcaat ggctgaaaaa gcgattcagc aaggcattac
     1801 gcatatttta tgcacaccac accacaataa tggaaaatac agcaatgaaa aatcacaagt
     1861 catttctcta gtcgcttcgt tacaagccga attagagaaa agacagttgc ctttgacgtt
     1921 attggaagga caagaagtac gtattaccgg aacgctcatc gaagacatcc accgagatga
     1981 aattttattt acagatttag atgatacata tcttctgatc gaatttccga cactggaagt
     2041 gccgttatat gcagaacggc ttttttttga gttgttagaa ctaggaaaga taccagtgat
     2101 cgtccatcca gaacgcaacg cgcattttcg agaagaccca aatcatttgc ttccgttcct
     2161 agatatggga tgtttggccc aacttactgc gccaagttat gttggtgtat ttggcaaaga
     2221 tatccagaaa acagccaaaa caatggtcaa acataatctc gtgcagatgg ctgcttctga
     2281 tgcacacggg gtctctaagc gcacctttta cttaaaagag tgctatgagc agattgccaa
     2341 ggagtttggt aaggaaaaag tagtacagat gaaacaagtc gcaaaggatc tgatcaacgg
     2401 ggatgagatc aattatccaa tctatgaaga ggtaaaaaag aagaagtttg gtttatttta
     2461 gttctttatt cgtagataaa aaggaaatga ggagagagtg agagatgtat agaaaaaact
     2521 caagtggttg gtctaaacat attgatttta ttttattaga cttattttgt gtccagcttg
     2581 ctttttatat atcatatgta atgcgacagg gtgactggaa tccgtatgtg attcctattt
     2641 atcgccacat ggcaattttt atagaacttg agaatcttac gattatattt ttatttgagg
     2701 catataaaaa tgttttaaaa agaggatatt ataaagaggc tgtagcttct ataaagcaat
     2761 cttttatgct gttacttgtg tgcagtttat accttattac aatgcaggat ggaaatgatt
     2821 attccagagt ttctttattt ataatggggg tggtgtatgg attattaaca tatataattc
     2881 gtatactttg gaaagggttg ttgcatcacc gcatgaaaaa cggtgaagat gtatcgttag
     2941 ttattgtaac atctcaaaag attgcaaaaa atgtagttcg taatcttaaa gagaagaatt
     3001 atggcatgta taaacttagt ggtgtgattg tagtagacag agatatgtat ggaactacca
     3061 tcggaggtgt cccagtagtt gcaaatgctg ataatgcagc ggaatatctt ttacagaatt
     3121 gggtagatga agtattcatc aatgttgacg aaagtgttcc atatcccaaa gaattaatcg
     3181 ccagatgttc ggaaatggga cttgctgtac atatgaatct tacaaaagtg tctgatagta
     3241 cacgtggaaa acaatttatt ggccgagttg gtgattatac tgttattaca tctagtatta
     3301 atgttatgac gatgaggcaa gcatttataa agagaacgat tgacattctt gctggaatta
     3361 ttggatgtat tgcaacaggt gttattttta tcttcgtagc accagttatt tacatcaaat
     3421 caccagggcc gattttcttt gcacaagaac gtattggtca aaatggtaag acatttaaga
     3481 tgtataagtt ccgtagtatg tatatggatg cagaagaacg caaagcagag ttgatgaaag
     3541 aaaataagat gagtaataat ctcatgttta agatggattt tgacccaaga atcattggca
     3601 ataaaatact tcctgatgga acaaagaaga caggaattgg acaatttatt cgatctacat
     3661 cattggatga gtttccacaa ttttataatg tcctaatggg aaaaatgagc ctggtggggt
     3721 ttagaccttg cttgaagtca gaatatgaga agtatgattt tcatcatcgt gcgagaattg
     3781 cgatgaaacc tgggattact ggaatgtggc aggtgagtgg tagaagtgat atcacagact
     3841 tcgaagaggt tgtaaaactt gatgcagaat atatcaggaa ttggagtatg ggattagatt
     3901 ttagaatttt gtttaggaca gtcaaaactg tgcttcatag aaacggttcc atgtaagata
     3961 aagatactat agaaggagta aaacgtgatg gcaagaaaaa aattaaaaat ctgtatgcta
     4021 ggtcataaaa gaattccatc aagagaaggt ggaattgaga tagtggtaga agaattggca
     4081 acgcgaatgg ttgcacttgg gcatgaagtg acttgctata atcgaagtgg tcatcatgtt
     4141 agcggaaagg aatttgacca gcataaaaat aaagaatata aaggtgtaaa attaaagact
     4201 atttttacat taaatataaa aggaattgca gcaatgagtt cttcagtatt tggtggaatt
     4261 agagcagcat tcggaaaata tgatgttgtt cattttcatg cagaaggacc atgtgctatg
     4321 ttgtggttgc caaaactttt tgggaaaaga tgtgttgcaa caattcatgg tctagatcat
     4381 caaagagaaa aatggaacaa gcttgctagt acatacatca tgttagggga aaagtgtgct
     4441 gtaaaatttg cagatgaaat aattgtactt agtgaaagcg tccaaaatta ttttgaagat
     4501 atatatggaa gaaaaacaag gtttatacca aatggcgtta aaaaaattga aataaaatca
     4561 gcaggattga ttacagaaaa gtatggatta acaaaagatt cttatatttt gtttttgggg
     4621 cgattggttc ccgaaaaagg aattcggtat ctaattgagg catttaaaga tgttcagaca
     4681 gataaaaaac ttataatagc cggaggaagc tctgatacag atgaatttgc aaatgaacta
     4741 aaggaattag caaaaggtga tgagcgaatt atatttactg gatttgtaca aggacaggaa
     4801 ttagaagaat tatatagtaa tgcgtatatc tatacacttc caagtgattt agaaggaatg
     4861 ccattaagtt tgttagaagc aatgagttat gggaactgtt gtatagtttc aaatatctca
     4921 gagtgtacgg aagtagtaga agacaaggct atgattttta agaaatcgga tgtaagtgat
     4981 ttaaagataa gattagaaga ggcatgcaat caatcggaaa tggttaaagt tttgaagaat
     5041 caagctactg agtttatttg tagtaaatat aattgggata aaatcgtaca agaaacatta
     5101 aatttgtata ggggaaatat ataatgattc gaatattaca gtgtgtgaat gatatgcatc
     5161 gtgcagggtt ggagacgatg ctaatgaact attataggaa tatagatcga actaaaattc
     5221 agtttgattt tttgacacat cgtccatata aaagtgatta tgatgaggaa ataataagtc
     5281 ttggaggaaa ggtctattat gcaccgagac tttatccaca aaattatcct aaatatttta
     5341 aatggatgga acaatttttt aaggatcatc cagaatatga gattgttcat tctcatattg
     5401 atgcgatgag ttatttacct ttaaaagctg caaaaaaagc tgggattccg atacggatag
     5461 cacatagcca taatacatcg atagatagag attttaaata tcttttaaag caatattatc
     5521 gatgtaagtt aacgtctgtt ttgacacatg aattttcatg tggaaaagta gcaggtgatt
     5581 ttttgtttcg aaatgataaa ttcactttga ttccaaatgc agtggatgct aaaaaatttt
     5641 attatgatga aagtattaga aatgatgtac gaatgaaatt aggaatttca agtcagacgt
     5701 ttgtaatggg acatattgga agaatttcat attctaaaaa tcatcgtttt ttgattgaaa
     5761 tttttaaaga atttcacgct attaagaata attccgtatt attaattatt ggaactggtg
     5821 atatggaaga agaaataaaa aattatgcaa agaaaagtgg catagatgat gatattaaat
     5881 ttttaggaaa tagaaatgat atagaaaaat tttatcaagc atttgacgta ttaatgttgc
     5941 catcattatt tgaaggggtt ccgttagtgg gtattgaagc tcaatttgca gatttaccgt
     6001 gtttcttttc ggagaaagtt cctacagaag ttgctttcag tgataagacc aatttcataa
     6061 gtttaaatca atcggcaaaa gaatgggcga gagagattgc aaatgtagat atctctcatc
     6121 gagattcaga acgttcgatt ttaataaagg cagattataa tattcaaaca gcatacaaaa
     6181 tcttagaatc aaaatattat gagttatttg aattaataca aagaggttaa agaatatgac
     6241 acagaaacat tcaagtataa aaagaattat acatcgcata tccgaagaat tgaatgcaac
     6301 aagacgaatt gcaaagataa catcttggaa ggaagcattt gccacgttac aagctaaaat
     6361 tgatattcaa gtcatgaatc gtaatggata taatgaaagt aaaaaacaga aggaacattt
     6421 attaaaaaaa catgaggtaa tgctgaagta ttatgaaaag actttttcag attttttgaa
     6481 aacatatgat tatagtcaaa atcaaataat taatcaatca aaatcaccat attctaactg
     6541 catttgggtt tgttggtggc agggattgga tcaatcgccg gaaattgtaa aagcttgtgt
     6601 aaaatcaata aaacgaaatg cagggaaaca tactgttata attttaacag aagataatta
     6661 tagacaatat gttgatatac caaaatgggt ggaagaaaag aaaaacaaag gaatcattac
     6721 gagaacaaat tattctgatt tattaagatt atctttgcta gcaaaacatg gaggtttgtg
     6781 gttagacgcc acattttatt gtacaaaacc aataccagat gagtattttg atatcgatat
     6841 ttggtctatt aggaggcctg attatgctca cgcatccgta gcatcaggat attttgcggg
     6901 ttattcatta gcatgtaatc aagagtctag atggatgttt gctataatta gagacttttt
     6961 tttaaattat tggaaaaata atgatatgat ggtggattat ttgatgatag attatatgat
     7021 tgttttagca cagagaataa atcatgaaat agcacagaca tttgataaaa tacctagtaa
     7081 caatccatta tgtgacgaat tgattaaaaa tttaaataat atatatgatg aaaaagtatg
     7141 gaacttatta aagaaagata ctttactgtt taagttgaca tggaaacaat cttttaaaaa
     7201 gcaaaaagat gataaagtta ctttttatgg gatgttggta gaaaacaaat tattataaat
     7261 attagaggta taaaaagtta tgaaacacaa ggtaagtgtg atagtaccaa tttacaatgt
     7321 tgaaaaatat ttaagaaaat gtgtggatag tttattgagt cagacattaa aagagataga
     7381 aatcgtatta gttgatgatg gttcgccaga tgcttcgggg gaaatagcag atgagtatca
     7441 aaaaaaatat tctaatgtaa aaacaataca tagagaaaat ggggggttag gaccggcaag
     7501 aaatacagga attgagaatg cgacaggaga atatgtggct tttcttgatt cagatgattg
     7561 ggtagaaagt gatatgtatg aaaaattata cttagttgcg tccaaagaaa atgctgatat
     7621 agtagttagt ggacattgtg attttgcgaa tgacaaagct atggtgaaaa agcaacatcc
     7681 tttgagtggg aatgtatatg atacgcctaa tagtattaaa aatgtacgaa aaaatttatt
     7741 tggacatagt ccaaaagatc aagaagtaga ggccttcccg atgtcagtat gtatgtcttt
     7801 gtataataaa aatctgctag ataaatatag actaagattt gaaaaaattt tatctgaaga
     7861 tacaattttt aacttgaatg catatgatgt cgcaaataaa attgctttta cagaatatac
     7921 agattattgt tatagaaaag aagaacaaga gtctattaca aaaagtttat ctccaaataa
     7981 gcagacggaa tttaaagaat ttttaataac tctaaaagct atagcatcga aagaagattt
     8041 agaatgtcaa atcagagcaa aacgtatggc aattgattat tgtaggcttt atgtgggctt
     8101 agttgatgat gcaaatttgg gaattaaaga gaaaagaaag tatataaaaa aatttattga
     8161 agatgaggga ttaattcaat gttggaaggg atatcctaca aatacgctac catttcaaca
     8221 aaaatttttt cataaaatgc ttgaatgtaa gtgttataca atattgttgt tgttaagtag
     8281 aattagaaag ataattaaaa atatgaccag aaaaaaattg tttataatat tataaactaa
     8341 aagtatatca aataatagaa attaacaagt tacaaaaaaa tattataaag aataatattt
     8401 tctaaaaagt aaactatagt aatgtggatt atcaccttcc aacagtatat aaaatgagcg
     8461 taaaaacggc tatttttgcc ttaacaacga tttttttgta tacaaatacg atatgctcat
     8521 taattattgg aatttgtagt gctgtttaaa ttaatgaagg tgtaattata tgagtgatca
     8581 ttttgaaaaa gtttgttgag aagatgtgct tctagtcatg tgatgggaga aaataattta
     8641 actgttagag tgaatagtta aattattctg gttatatgaa aaaagtagtt tctaaaataa
     8701 tcttgcaggg attaacttaa agaaattgag agaatagttt ctttgaaatt tctatataca
     8761 atgagaagct gaaatttact tttatttgat gactggaaat agaaattaaa tatattgtat
     8821 tgttacatta aagaaaactt gtatggaaaa atcagtacaa taccattatt taatgttctt
     8881 cacttaaagc gcaaaaaata tcagtttatt aaactcgtat atagaacaaa tatatgtaga
     8941 cggggcgaaa cgatgagtgt aaaaaaaatg ctatttatgg taagtacaat aattgtatta
     9001 acatcccgat tttggggaat taatactagt ttatctatgc gatattttat tatggcaata
     9061 tgggatttat attttatgtt aagctatttt tcttatcgtg agaaaacata taaaaaatac
     9121 gttatcaaga ataacttttg gttgactata atgccgtttg tgatattttc tatctatact
     9181 ctaataatat ggggaattgg ttcaaatgca gaatttgaaa attttataaa gttatgttcc
     9241 acgttgcttt atttaattct tgcatatggt tacgcatgta cagcatttta cttatttaag
     9301 gcagaaggaa ttgattttat tttttggtca ggtgttattt catatatgag tggttcagtt
     9361 ttttatttaa ttgtatctta tggtttaaat ggtttaattt cttatataaa aagtcttata
     9421 acaggtgaaa caaatactgc aaattttgct atggaggtac atgatttaac ttttgcgatg
     9481 ggggtttttt tcctttatta cgtatttttt gaaaataaaa atacaaaaaa acataagata
     9541 aaaattatcg tatctttaat tttaattttc atgggattga agagaattga actgttagct
     9601 ttaagtggtg caattctagt gtattatgtt ttattaaagt ggggaaaaaa gattcaaatc
     9661 cgtgcattag tgtgtactat ttgtgcaact gttatttcgt tagtgtttat ttacattata
     9721 gatacaggaa ttttggcatt gcttatgtca aatttgggca ttacagatga cggtgcgagg
     9781 ctttcatttt atctatattc atctaaattt tatgaacttg gtttaggata tgtaggaaca
     9841 ggatggacat ggttttcaaa atactttttt aatctttatt tatcgcactt taggttaaat
     9901 ggtggaagaa ttgcagcaag cctacacagt gatatattaa ctatttatat agaagttgga
     9961 tgtatagttt ttattatatg gatgttttgg ttattttttg tgaaaccgat aagactaact
    10021 aaaaaatttg gattgaaaac aggggagtgt gtattattat taactatata tatgtttata
    10081 ttatatttga cggataatac gctcacttat ccagacactc aaatgatttt tctcttagta
    10141 cctatgatag tttcgtgggt tgataatcaa caacgaatat cggaatagat agctaaagta
    10201 tattttaatt atgaatttat aattagttgt aaaagttaat atttaacgga caggaagtag
    10261 ggtgaaaaaa tttgaaaaaa attttagtgt tagcaaatac atattatcaa ataatagtag
    10321 caatacaaat gaaaaataca attttttccg atgagtatgt tgaaattatt atttctgatc
    10381 attctaaaaa cactaaagaa attgcgaaaa aaatagaaga aaaaaaagtg tttgatggct
    10441 gtcattattt agaaagcaaa tcttttgatg ataatattgg gtattttcaa aagattaagg
    10501 actgtcttca gatttcttgt ggtaaatcaa atcgatatgc ctattatttg aaaaactgta
    10561 aaagtgaata ttttgatgaa tttatttgtt tttcaatggg agaggtttgg ttggaaggaa
    10621 tatatgcttg cttatatcga aataataaaa atgtacaggt atcaatttta gaagaaggta
    10681 ttttaagcta tggagttgac attattccaa cagcaagaac aaaagctatc gcagtactca
    10741 attacttaaa aaaaaggact ccactatata acaaaagcta taatttttat tgtttttttc
    10801 ctaatatata tacaggaaga gagaatacaa tacaaattcc attagttaca gctgggtcaa
    10861 gaaccgcatt gcaactttcg gatattttta accctatgat agatatttat aaagaaaaaa
    10921 aatatatatt ttttacgtct gtttatgatt ttgagggcgg agaacctgtc ggagaatatg
    10981 aattagtatg caaaatagca gacttagtag gaaaagataa tctaattgtt aagacgcatc
    11041 ctagagatgt aagaacaatt tataaagata atggatttat cgaggataaa aattcatcaa
    11101 taccttggga ggcgattcaa ttgtcaggcg attttaacga taaaatattt atgacaatta
    11161 attcaggaag tgttatttca ggtagtacaa tgtctgcaaa acctgtacgc acgtattata
    11221 tgtataaatt gtgtaacata gaaggaaatc cgtcttgcaa aaagaatgcg tatgatattg
    11281 agcgattgct taagcaaaaa acgatgaaaa acattttaaa gaatgtgaaa atagcagaaa
    11341 gcttagatga tatactatga gcaaaactaa atatttaatt aaaaatatgg gaatattaac
    11401 aataagtaat ttttcttcaa aaattttagt ttttttgtta gtccctttat atacaagtgt
    11461 attatccaca acagaatatg gcacatatga tttgacaatt tcaacagcca cattattgtt
    11521 tccaatttta accttaaaca ttgtagatgc tgtgatgcgc tttttaatgg ataaagataa
    11581 aaataaaaaa aatatagcat ctatagcgat taaagttata tttttaagcg tgatagtctt
    11641 tggatccgta atgtatttgt taaatattac aaaattatgg caagatgttt atggattaga
    11701 aaaatatatt tttttgtatt atatatccta tgtatggaat caatttctaa tacaatttgc
    11761 taaagggtta gaaaaagtta aagctatggg catagcaggt attatcagca caattgtaac
    11821 aataattgcc aatattttct tcttgcttat tctgaaatgg ggattaattg gttttttcat
    11881 tgcaaatatt ttatcacaga ttatttcagc tacttatctg tcagtattag tgagaatatg
    11941 ggaatatatc gattttgagg ctaaagatcc tcagctaaag agagaaatgc taaattactc
    12001 gattccatta attgcaactg ttgttggatg gtggattaat agtacagctg ataggtatgt
    12061 ggtttccttt atagtaggtg tctcggcgaa tggcttattg tctgtggcat ataaaatacc
    12121 tcaaataatt aatactttgc agggaatatt tatacaggcc tggcaaattt ctgcaattaa
    12181 agaatatgga gataatgaga ctgcaaaatt ttatggaaat acatttgtta tgattaattt
    12241 gttaatgtgc ataacctgtt caagtcttat catattaact agaccgtttt cacatattct
    12301 ttatgcgaaa gacttttatg aagcgtggaa atatgttcca tttttattaa tagctaatgt
    12361 tttaaattgt gcatcaggtc tgttaggacc tatcttatca gcaaaaaaag attctaaatc
    12421 catgatgtgg tctgcaatca taggggcatt agttaatgtg attatgagtg tagtccttgt
    12481 ttataagata ggggttcaag gtgccacaat agccactgtt atatgttcat atgtaatata
    12541 tgttgttcgt aaacgagctg tgggaaaaga tatttttata aagcattatc atattgttgt
    12601 ggaatcttgg ggattattgt ttgtt
//
LOCUS       DAFTHM010000077        12162 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFTHM010000077 DAFTHM010000000
VERSION     DAFTHM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.077"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..881
                     /gene="gnd"
                     /locus_tag="L7C88_002066"
     CDS             <1..881
                     /gene="gnd"
                     /locus_tag="L7C88_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBP9558875.1"
                     /translation="GKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAYQEISE
                     FLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRAEEFQK
                     NEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGASGSGH
                     FLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEIMEDQL
                     NEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFSAKVVS
                     ALRNGFGGHEIVEKGE"
     gene            883..1884
                     /locus_tag="L7C88_002067"
     CDS             883..1884
                     /locus_tag="L7C88_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBP9558876.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            1881..2165
                     /locus_tag="L7C88_002068"
     CDS             1881..2165
                     /locus_tag="L7C88_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBP9558877.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            2198..2995
                     /locus_tag="L7C88_002069"
     CDS             2198..2995
                     /locus_tag="L7C88_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBP9558878.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            3009..3842
                     /locus_tag="L7C88_002070"
     CDS             3009..3842
                     /locus_tag="L7C88_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9558879.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            3860..4717
                     /locus_tag="L7C88_002071"
     CDS             3860..4717
                     /locus_tag="L7C88_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBP9558880.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            4739..5248
                     /locus_tag="L7C88_002072"
     CDS             4739..5248
                     /locus_tag="L7C88_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9558881.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            5285..5686
                     /locus_tag="L7C88_002073"
     CDS             5285..5686
                     /locus_tag="L7C88_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558882.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            5798..6151
                     /locus_tag="L7C88_002074"
     CDS             5798..6151
                     /locus_tag="L7C88_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558883.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            6185..6628
                     /locus_tag="L7C88_002075"
     CDS             6185..6628
                     /locus_tag="L7C88_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBP9558884.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            6645..7730
                     /gene="uxuA"
                     /locus_tag="L7C88_002076"
     CDS             6645..7730
                     /gene="uxuA"
                     /locus_tag="L7C88_002076"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBP9558885.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            7723..8436
                     /locus_tag="L7C88_002077"
     CDS             7723..8436
                     /locus_tag="L7C88_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBP9558886.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(8643..8792)
                     /locus_tag="L7C88_002078"
     CDS             complement(8643..8792)
                     /locus_tag="L7C88_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558887.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            9188..9388
                     /locus_tag="L7C88_002079"
     CDS             9188..9388
                     /locus_tag="L7C88_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBP9558888.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            9956..10519
                     /locus_tag="L7C88_002080"
     CDS             9956..10519
                     /locus_tag="L7C88_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558889.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(10580..10945)
                     /locus_tag="L7C88_002081"
     CDS             complement(10580..10945)
                     /locus_tag="L7C88_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558890.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(11021..11266)
                     /locus_tag="L7C88_002082"
     CDS             complement(11021..11266)
                     /locus_tag="L7C88_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9558891.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(11336..11590)
                     /locus_tag="L7C88_002083"
     CDS             complement(11336..11590)
                     /locus_tag="L7C88_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558892.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(11754..12077)
                     /locus_tag="L7C88_002084"
     CDS             complement(11754..12077)
                     /locus_tag="L7C88_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558893.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
BASE COUNT         4191 a         1916 c         2575 g         3480 t
ORIGIN      
        1 tgggaaaaat gggattgaat ttagctttaa acttaaaaga gcaccatcac aaagtacaag
       61 gactcgacat ttcaagtaca gctgttagtc aggcaagaga aaatgacatt cctgcttatc
      121 aagagatctc tgaatttcta gctacttttg agcagaaaaa aatcatctgg ttaatgcttc
      181 ctgctggaga gataaccgaa aacatgttaa gaaaactttt tccaaaactc ggaccaggag
      241 acattattat tgaaggcgga aactcttatt ataaagattc aatccgtcga gcagaagagt
      301 ttcagaaaaa tgaaatcggt tacttggatt gtgggacttc tggaggaatc gaaggagcac
      361 gacatcaagc ctgcttaatg attggaggag ataaagaaac ttttctatcc gtggaacaat
      421 tattcaaaga tgtagcaatt gaaagaggat atctgtatgc tggtgcatcc ggaagcggac
      481 acttcttgaa aatgatccat aatggaatcg aatatggaat gatgcaagca atcggtgaag
      541 gattccaact tgtacaaaaa agtgagtatg cttttgactt ggaacaagtc gcacgtgttt
      601 ggaatcatgg ttcggtgatt cgcggctggc tgatggaaat catggaagat cagttaaacg
      661 aacatcccaa tttaagtaat tatcggggaa tcgtttctgc atcaggtgaa gcaaaatgga
      721 cggttgaaac agcgctagaa atggctgttc cagttccagt aattgcaact agtttgttca
      781 tgaggaatct ttcacaggaa gaagatagtt tttcagcaaa agtagtttca gcactaagaa
      841 atgggtttgg cggacatgaa atagttgaaa agggtgagta aaatgccaga ttatcatata
      901 gcaatcgtta attccagcag tttcggaaga gtctttccac accacttgga aagattaaag
      961 tcagttggag acgttcattt ctttactgtt gatcaagaga ttccaggaaa agaactagcg
     1021 gagttactta aaggattcaa tatcattatt gcaagtgtta cgccattttt tcgacgagat
     1081 ttttttgaaa acaaagatga actgctattg atttcccgac atggtattgg ttacaacaat
     1141 attgatttaa aagcagcaaa agaacaccag acaatcgtat ctatcatacc tgctttagtt
     1201 gaacgaaatg ctgtagcaga aaataatata actaatttgt tgtccatgct tcgacgcacg
     1261 acacaagcac aagcaagagt caaggacgat cgatgggaag atcgggcgga gttcgtcggt
     1321 aggacgctgt ttaacaaaac agttggtgtg attggtgcag gaaataccgg aagcggagta
     1381 atcgaaattt tgcgtaacgg ttttcgctgt gatgttctag cttatgatcc ttacaaatca
     1441 gatttataca tcgaaagctt tggtgcaaaa aaagtagaac ttcaagaatt actggaacaa
     1501 tcagatatca tttgtttatg tgcgaatttg acagaagaga actatcacat gatttctgat
     1561 aaagaagtcg atcagatgaa agaaaatgtt tatctatcta atagtgcaag aggcgctcta
     1621 gttgatgaag aagcgatgat taatggtctg aaaagcggaa agatcgcagg atatgccaca
     1681 gatgttttag aagaagaacc gggacgtcaa gatcatccgt atttagcgtt tgaacaagta
     1741 gtgattacgc cacatatatc ggcctacaca agggaatgtt tagaagcaat gggtgaaaaa
     1801 tgtgtcagag atgtcgaaca gatcagtcag caccttcttc ctgaacgttc tgtccagaca
     1861 aagagcaact atataaaagg atgatgaaga aaatggtgaa cggtttaaaa gtgaaaacag
     1921 gccctcaatt ttatttatat gaagaaggtg gtatttcaaa agtttctgat ctcttgaaat
     1981 catacggcgc gaaaagagta ctggtcaccc acggaacggt atcatgggaa aaggcgctac
     2041 ctaaattagt atttttgaat gacgaaacga ttcaattttt ttatcatcgt tattctggag
     2101 aatgtagtta tgctgaagcc agacgaatag ctacaatcat caaaaaaatg aaatcgattt
     2161 cgtagttggc gttggcggag gaaaactgac cgatctagtg ggttatagtg ccaatcttgc
     2221 aagaatcgat ttcggagtca tccctacttt agctagtaat tgtgctccat ggacacctct
     2281 tgctgtcatg tataaggaga atggacaagc agaagggaaa acagaacact tttacagaca
     2341 agctgctttt tttataacag atccccaatt agtgattgat tcccctgttc catatttcat
     2401 tgccgggtta gcagatacac tagcaaaatg gtatgaatct gagctcatct tagaacaaga
     2461 ttttttgcaa gatgaatcat ttttgaagct agcacaagat actgcgaaga tctgcaaaga
     2521 agagattttg aatcattctg ctaaagcaat ccaagatatg gcacaaagaa aactgacatc
     2581 ggagttcaaa cagctttcag agattatctt tgctgttgct ggtttagttg gaggattagg
     2641 agataaatac gcaagaaatg tggcagcaca tgctatgcat gacgctatca gtaaatatat
     2701 tccggaaagc catcgttttc tacatggaga aaaagtagcg tatgggattt tctatcaact
     2761 ggcactagaa ggtcgctggg aaaaaataga cgagttatat cctttgtatc gggaattaga
     2821 actgccggtt tctctagaac aaatgggatt atttccgaaa gataaacaga taatagataa
     2881 aatggctgaa tttattgatt cgaaagagaa agtgcatttg attcctatag aggtaacaca
     2941 gaaatcactg atacagtcaa tgatggaact ggaaggttat atcagaaaga tctgaaggag
     3001 gaggacacat ggaaacatta agtgtagtac aaagtttgtt gattgcttta tgggtagccg
     3061 cggttatgtc ccgctggtta ggtggaggag ccacgttgac cttacgtttt tctcctttga
     3121 tgactggatt agtcgtcggg ttgatcatgg gggaagttgc acaagcgatg attgttacag
     3181 ccgctttgca aatgatttat atgggggttt tttctccagg aggatcaatg ccagctgaac
     3241 catctattgc agcagctatc gcagtaccag tcgcattatt aggggatctg tcgccagaag
     3301 cagcgattgc cgttgcggtg ccagtcggat tgctcggaag ttacttgtat cagtttcgtt
     3361 ttttcatcaa tactttttta ggtaaatata cagacaaagc tgtagaagat ttgaatacaa
     3421 aagctatggc ccgatcaatt attctttatc caacggttgc ctcattttta ttattcgttc
     3481 cgcttgtttt cattgcttta tatttagggg cgccattgat cgctgatgta atcaaagctt
     3541 tagagggaac agtcgttatc cacattcttg aagtagtagg tggagggtta gcggcaatcg
     3601 gtatcgcgac aactgtatac gttatcggtc gaaaagatta tctggtcttt ttcttccttg
     3661 cttattttat gagtgttgtt ttgaaatctt tagatattac gatggttact tatgccattt
     3721 ttgggattat tatcgctttg atctttgtcc agtcgcaaaa agggaaacaa gtacagcctg
     3781 ccacaagcaa taacaattca gcatcttttg atgacgaaga tgactatgat gacggatttt
     3841 aatttaggag gaatgggaaa tggctgaaat aatggataat caaacaggtg ctcctgaaga
     3901 aatcacgaaa aaagatgtaa caaaagccta tctgagatgg cattttgcaa acgaaattcc
     3961 tcactctttt gaacgttact tggcgccatc actactatac ggaatgatgc caatcttgaa
     4021 aaaactttat aaagatgaag actctttaaa agcagcatat aaacggcagt tactgttctt
     4081 caacactcaa ttaagctggg gtggcggtgt gattactggc ctaatgtctt ctatggaaca
     4141 gcaaagagca gaagaagagt atgaagaaaa agagatcttg atgcaggatg acttgatgta
     4201 taacacgaaa gcgggattga tgggggcact agcaggaatc ggagatgcaa tcgattcagg
     4261 aaccgtccaa tatattttta tcgcaatcgc ggtaccttgg gcacaacagg gaagtccttt
     4321 aggcgcactt tttcctttta tctgctttgg gttgtatcag gttttactag gggtattttt
     4381 cgcaagacaa gctttcacta tgggccgtaa tgctacaggc ctaaagcaaa acactggtgt
     4441 tcagacagcg attgaaatgc tatcagtttt agggttgttt atgatggggg tgcttgcggg
     4501 aaactatgta aaagtagaat cttcattgaa atttgcgata tccggacgtg agtttgttat
     4561 ccaggaaatt cttgatcaaa tcgtgccagg gatattacct ttagctgtcg taatgggtgt
     4621 gtacttgttc tatacgaaaa aaggattgaa agtcacacaa gcattattat ggctgactgg
     4681 aatattaatt gtgctagcag gaatcggtat tttataaaaa gaagggaacg tgaataagat
     4741 gggtgtagtc aatttagcgc gtgtggatga gcgtttgatc catgggcaag taatggtaac
     4801 gttatctcaa aaaagtggag tgaattccat ttttgttgta gacgaagttg tagcaaaaga
     4861 taaatttatg agagatcttt acaaaaatgc aggaagccgt acaggacaaa aaacaattgt
     4921 cattacacca gagaaagcta aattctattg ggatgaatat caatttaaag aatacaattg
     4981 tattttgatc gcaaaaacag tccaaacgat ttacgactta gtaaaacacg gaatccccat
     5041 ggaagaattg aatattggag ggattgctca aaaaaatcct gatacagatc ttttagtgac
     5101 gaaatctgtt tatttaaata aatcagatgc tgaaaaattg aaagaaatga atgaacaata
     5161 tggcgtaaag aatatttatt ttcaagccac tccatctgca cctaaaacag gattaaaaga
     5221 tgtattgaac aagtttgatt tgtcataaac aaatgcttag aaaaaagata aagagggcga
     5281 aaaaatgaag aagaacgagc tgtttcgtga ttgggaattt cgttatcgct atatttaccg
     5341 taagcgccgt acaaaaaaga gtaaacagcg ttttctttca gcattagtat cagatattta
     5401 cagtatgaga acagatgtga cagtcattgc ttacgatacg ctagcctacc gatcaaaaaa
     5461 tatttatgtt ggagatatcg aaaaagcaga gaaagttatc tgtacttatt acgatacacc
     5521 cgttcatgca ttaggaagtt atttcatgtt tgattggaaa gaccaaagga aaaaaacaat
     5581 ctactctata ttattgtcct tcattttgtt gttcagttta ggttggtggg gaatgatgat
     5641 atataacaaa aatcctcatc acgtattcga tctgctatcc gtataaacag gtatcactgt
     5701 actagcattt gggagctact ttttcttatt gggaaaagca gctcgcggat ggcctagcag
     5761 acaaactttt attcgaaata cttcatccat attaacgatg ctagaaatga tccgtacgat
     5821 tgatgatccg agtgtagcgt atgcgtttgt tgatgaaggc tgttatggag aaaagggctt
     5881 agacagcgtg agatcgggta tgaaaaaaga ggctattctt ttttatctag actctgttgg
     5941 ggcagataca ccgctacagt tttcgggaaa ttatttttca aataaagaac agtggctgaa
     6001 acaagttgat aagttgaaag aaaaaaacgt caattatatt tttagtgcaa gaaaaaagca
     6061 agcgcagttc ttctatttga ccaaaacaga tttacgaggg aaaacattta attggcaaaa
     6121 tgccaatcag attattgctc tttttcgata agtaaaaagt gcaaaacaag gagtgagaag
     6181 actaatgttg gaaatcatga tcgttacaca tggtaagttg agcgaaggac tgaaagatgc
     6241 ggcggaagta attgtcggga catcgagcca tattgaaaca atgtgcttag agtctgggga
     6301 ggacatccaa acattcggag agaaggtcaa agaaaaatta actatgatca acacagcaga
     6361 acccatgcta gtatttgttg atctaattag cgcaagtccg tacaatcaag cgctcttggc
     6421 agtcaatgaa ctgactgaag aaaagaaagc agccacttat gtcatagggg gcgtgaatct
     6481 gccaatgttg ttagaagcaa tcaatcatca gatgcttcac acaccgatag aagaagcggt
     6541 ggaacaaatt gtcaaacaag gaaaagataa tttaactgtt tggcatgctt cagcggaaga
     6601 aaaaaaatta gatgaggacg atttttagaa ggaaggctga aaagatgaag tggggattta
     6661 gatggtatgg tgaaaaaggg gattcgatcc cattaaaata tgttcgccaa ataccgggaa
     6721 taaatgggat aattggaact ttgctgacta aaatgcctgg agatgtttgg gagatttcag
     6781 aaattgagga gttgaaagca tctgttgaga gccaaggact ggaactgctt ggaattgaaa
     6841 gtgtagcgat ccacgatgca atcaaggcag ggacagatga acgagattac tatattgata
     6901 actatatacg aacaatcaaa aacttgtctc gatgtggggt tcgattgatt tgttatagct
     6961 tcaaaccaat ttttggatgg gcgaaaactg atttgtttaa tgaaaacaac gatggaagct
     7021 attctctttt atacgatcag aaaatcgtcg atcagatgga gccaggagaa atgtatcaat
     7081 tgatacacag ccagtcaaag ggattcaaat tgccgggttg ggaagaagaa cggttgaaaa
     7141 aattcgctca gctggaaaaa ctgtatgaag gaatgaccga agaagaatta tttgaaaatc
     7201 tgacttattt tttagaaaaa gtgattccag tgtgcgaaaa agcagatgta aaaatggcta
     7261 tccatccaga tgatccgcca tgggaacttt ttggttttcc tagagtgacg aaaaatcttg
     7321 gcgacttgaa gaaaattcta aatgcagtag attctccata taatggacta acgctgtgca
     7381 caggatcttt aggggcaaat ccggaaaacg atttagttga aatcatccat gaggtaggtt
     7441 cgcgcatcca ttttgtccac ttcagaaacg tggagttttt aggagaaaga aagttcaaag
     7501 aaacggcaca tccctctaca gaaggctccc ttgatatgta tcatattatg aaagcgttgg
     7561 tgcaagaagg gttcgacggt cctatacgcc ctgatcatgg tagaaccgtg tggggtgaag
     7621 tggctatgcc tggatatggc ctgtatgatc gtgcaatggg actcacttac atgcaaggtc
     7681 tatatgaggc gataagtaag gaaaaaccac tgggagagca ttatgaataa aatcaagctc
     7741 ttcatctttg atatggatgg ccttttatta gaaactggac gtttagctta tcgtgcttat
     7801 gtaaaatcag cacaaaagta tgattatgaa atgcgtaagg aagtctatta tttactaact
     7861 ggccaaacag aaatggcgat aagagaacaa atgggcattt tgtacggaga agatgttcca
     7921 tatatcaaat ggcgagaagc aatcaatcaa tataaagaaa aaatcgtgaa agaagataag
     7981 agagtatata cgaaaaaagg agcagaagaa attttatctt ttgcaaaaga aagaggaatc
     8041 catacaatcg tggcttcgtc taatacacgg gtaaaagtag aaatgtattt aaaaatggaa
     8101 aatctatatg ccttgtttga tcaaatcatt tcaggggatg atgtaaaaaa aggaaagccg
     8161 gaaccagaga tctttttgaa agcttgttca aaaatgaata ttcctccaag tgaagcactt
     8221 gtatttgaag actcgattgc agggatcgaa gcagcaaggc gagcgggcat tttgtctttt
     8281 ctcatcaaag atcatttgat agggttgccc gatcataatg ggaagcataa gttgaaagta
     8341 gatgtaagtt tatatgaatc caataaagca gactatgaat tttatgacct gcatcaagca
     8401 aaacgatttt tagaaagtaa agggttgtat ctctaataaa gaggactatt ttctagtcct
     8461 ctttatttat tgtcctgcac gactgaggga acagatgaaa aagaagtaat tttttatttt
     8521 gaagtatcta ccttatttgt agtgaacaat ttagaacaaa cacaaaacgc atctactgtt
     8581 atctaccagt agatgcgttt aaagagaaga acgagaatcg tccatatgag ggtttccact
     8641 ccttatgcag atttttttaa ttcttgcact gcttgttcga tcgtaacacc tgtcgctaca
     8701 tgattggtat tttctttgtc aaaaacgaca aatagattca aatctgtatc caaggttact
     8761 cgatattgta tatctttgtt atagaatgtc atagccattc tcctttcttt aaatacttgc
     8821 tgaaaggcaa cgaacgcgtt gataacgaaa ttccatttat aagtatacca ccaattgaaa
     8881 ggttttcata gttaagaaat tttaaagtca aaagttgcag ataaaagcaa ataaacaaga
     8941 aaacaaaaag tgaatcaatc gcggttattc aactttttct tcgattcgaa gacaatagaa
     9001 gacaatgaat tttatatttc attgcattat ccttgtgtta ttagaaaaag catgatatat
     9061 taaatgagta atctattttg aaacgtaatt tgagcgatat atctacatag ataaaactcc
     9121 ttttgcctat caaatattta ttgcaacgaa aaaacgtaca ttgatacgta tcaggaggaa
     9181 tttatttatg aataacggta cagtaaaatg gttcaacgca gacaaaggtt ttggctttat
     9241 cactggtgaa gatggaaatg atgtatttgc acatttttca gctatccaag gtgacggctt
     9301 caaaacttta gaagaaggcc aagcagtgtc ttacgatgtt gaagatggtc aacgtggccc
     9361 tcaagcaaca aacattgtta aagcttaata aaaattgact tttaaccgtc ttttcgaaag
     9421 aaaagacggt ttttttgtac gaaaaaattc attggtcgtt gaatgggctg aatagtagtg
     9481 tataaaacaa ttttgtggag cgtgaagctt ttatggtaga ggaaaatacg aataaagtga
     9541 tgttgataaa aagattccta tcttgaatat gaatcgagat gtcttgaaaa tgaatgagtt
     9601 tgaccaatca ttatcctatc gaaatttaca gtttcgttcg attggtctgt caattaatga
     9661 aaaagtaaaa aagaatatgt tctaggaaga gggcggcaca tctaaatttt taagtaacgg
     9721 acagttcaaa tatcaagcat tgaaagaggc tatcctactg tttgaaggaa tacgaatata
     9781 taaaaacgac aaagaggaaa aagtagttca ttaaatccct tcaagtgatg aaagaatgag
     9841 atctaataaa acctgatctt tcatctgttt ttttaataac gtaataattt ttttattttt
     9901 tgtgctttcg ccgttattgt agagtgattt agcattctta tttttaaaaa taactgtgtt
     9961 atatattaaa aaaggcataa tagttataag cttttttaaa gaatatttag aaattattaa
    10021 ttttcgtctg aaaacaaaaa aagaaagcgt tattatttta gtctattttc agggggggaa
    10081 ccttatgata aaaaaactat ttttactatc aatattaacg ctagcaatgg caggttgttc
    10141 tgactctggc ttagcaactg aactgatcac aaaatcaact gaagccacga cagaggagtt
    10201 aaaatgtgga aacgatcaca gtgactacag aggcttaaat cgacgatgca tgggaatatt
    10261 aggcagaagc aattgtaagc atcgatgtag taatcgaaga aggtgtagaa gaagcaacag
    10321 aaaaatcaaa agaaagatca aaagaagcaa tctgtgctgt gcatcgtata cagacgtcga
    10381 agatgcggta cttttaaacc acgtcaggag atgttcattt atgtctaggg aagttggcga
    10441 tgaaccaaaa ctagagtacg cttttagttt tgcacgtgag gatgaagata accctaaaac
    10501 ttacgacatt ttagcttgat ctaagatggt taaagctttt taatgaagta agaggagata
    10561 gaaggctttt ctagttatat taggtaagat aaattccttt ttgctccaaa tttgctaaac
    10621 attctgctag ataaacttca tcgtgttccg gataaatcgg cacgttgcgc tctacagtag
    10681 gtaaatcaaa aaatgcttcg catgatttgc cacgatacat aggatttttc cactctggtg
    10741 ctgggctgta accacgtttt tccatttcat ccatgacaag ctgatgatat tggaataatc
    10801 tataaggaga atagtgaaaa acataatcca cagtagcatg tttctttccc cagccatttc
    10861 ctcttaatgc acagcattcc cgatgttgtc ctaaaagctg ttgacgagga agctttgaaa
    10921 tcaatttttc atgccataat cgcatagaaa tgtctccttt atatatagat tgttaacctt
    10981 agacgttaaa tgaaaaaacc agcaccaagg ctggaaaaaa tcacttcagt ttgcttgctg
    11041 tttctgagcg accaattagg taatcaacgg aaatatcgta aaagtcagcg atatagatta
    11101 attcaatgat gcttggaatt tcttctcctt cttcgtactt acgatatttg aataaaggaa
    11161 tacttaacgc gctagaaaca gctacttgag ataaagatcg gccagttctt aagaaattca
    11221 gacgacaacg taaagtatcc agtaaaatag cttcttcgat actcatttaa tcacctttca
    11281 ttatagtaga atagttataa tgactataga aagctacaca tgcaatcaat agtactcaat
    11341 gttttttatt taaacgtatc aaataaagaa tgacgatcaa taaagacaaa accagtcctg
    11401 ataattcttc tataaaaaca ctatcgggtt caaagtagtt gtaattaaaa actttccaca
    11461 taaagtagat agccggaaga gtcaaaatag ctaaataaaa ccgttctttg ttccaattca
    11521 taagataaac aatacttgcg accagtgcga ccgcaggcac ccaaaacaaa actctcacca
    11581 acgtaatcat gtaacggact cctcaacgat tcatataata aaagataaca tgttattgca
    11641 tacatcacaa atgaaatgct aggaaaataa aagaagaata gatcaatgaa aaatgaaaaa
    11701 gcagaacagt tttctgctga taagcaggaa ctgttccgct gaatgtgtct tatctatcga
    11761 gaaaaaatca atggattgat atctaagtaa ttcaatacat ataaaaagag gacgatcgca
    11821 ttcactaaaa aggaaagaat gatgatccca tagcgaatgg aaacatattt aacaaatact
    11881 tttgtttgaa tacgggcata tctttttcct ttatagctga gcatcatgac aagaagcaaa
    11941 agggtaatca caccttgaaa aatcattcca ataaacagaa ttcctgaggt ttgataattt
    12001 aattggagaa aataagctgc tgccgcaact aaatcgaata aaatcgcaat aaatggcaaa
    12061 ataatcactc ctaacattga gaataaataa aagaataaca ttttttctaa aataagcaaa
    12121 taaaaattaa agtaacaaaa tagttatgac acaagtaaaa ga
//
LOCUS       DAFTHM010000078        12150 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFTHM010000078 DAFTHM010000000
VERSION     DAFTHM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.078"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(33..590)
                     /gene="frr"
                     /locus_tag="L7C88_002085"
     CDS             complement(33..590)
                     /gene="frr"
                     /locus_tag="L7C88_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBP9558894.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(593..1315)
                     /locus_tag="L7C88_002086"
     CDS             complement(593..1315)
                     /locus_tag="L7C88_002086"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBP9558895.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1451..2332)
                     /locus_tag="L7C88_002087"
     CDS             complement(1451..2332)
                     /locus_tag="L7C88_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBP9558896.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2431..3213)
                     /gene="rpsB"
                     /locus_tag="L7C88_002088"
     CDS             complement(2431..3213)
                     /gene="rpsB"
                     /locus_tag="L7C88_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBP9558897.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3572..4051
                     /locus_tag="L7C88_002089"
     CDS             3572..4051
                     /locus_tag="L7C88_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBP9558898.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4268..5359
                     /gene="phnW"
                     /locus_tag="L7C88_002090"
     CDS             4268..5359
                     /gene="phnW"
                     /locus_tag="L7C88_002090"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBP9558899.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5352..5480
                     /locus_tag="L7C88_002091"
     CDS             5352..5480
                     /locus_tag="L7C88_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBP9558900.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5484..6029
                     /locus_tag="L7C88_002092"
     CDS             5484..6029
                     /locus_tag="L7C88_002092"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBP9558901.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6483..8174)
                     /locus_tag="L7C88_002093"
     CDS             complement(6483..8174)
                     /locus_tag="L7C88_002093"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBP9558902.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8594..9541)
                     /gene="arcC"
                     /locus_tag="L7C88_002094"
     CDS             complement(8594..9541)
                     /gene="arcC"
                     /locus_tag="L7C88_002094"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBP9558903.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9656..10675)
                     /gene="argF"
                     /locus_tag="L7C88_002095"
     CDS             complement(9656..10675)
                     /gene="argF"
                     /locus_tag="L7C88_002095"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBP9558904.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10766..11995)
                     /gene="arcA"
                     /locus_tag="L7C88_002096"
     CDS             complement(10766..11995)
                     /gene="arcA"
                     /locus_tag="L7C88_002096"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBP9558905.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3316 a         2525 c         2197 g         4112 t
ORIGIN      
        1 gaatgatccg cccctctgtt tttatgattt tattaaactt ccaataattc tttttcttta
       61 tcagcagcga tcttatctac ttctttgatg ctgttatctg tcaatgtttg tacgtctttt
      121 tctaatccgc gcaaatcatc ttcggtaata tcaccatttt tttgttgttt tttatattca
      181 tcgatcgcat cacgacggat gttacgaatc gcgatttttg cattttctgc ttctttttta
      241 acatctttag ctaattcttt tctgcgttct tctgtcagtt gcgggataac taagcgaatg
      301 acatttccat cattggttgg actgattccg atatcacttg ccataatagc tttttcaaca
      361 tcttgaagaa tgctcttgtc aaaaggtgtg atcattaaaa cacgtgcttc tggaatttgg
      421 attgatgcca tttggttcaa tggtgttggc gcaccgtagt agttcacagt aatacggtcc
      481 aaaaggctag cgttcgcacg gcctgcgcgg atttgcccaa gttcacgttg aagattttgt
      541 gctgcttttt tcattttttc ttttgcttct gtcataattg catctgccat ttttatttcc
      601 cccttacagt tgttccgata ttttcgccta agattgcacg gcgaatattt ccgtgttcat
      661 ttaaattgaa gacaagcagt ggaatatcat tatccatgct tagtgaactt gcagttgaat
      721 ccatgacttg taatcctttg gcaataactt ccagatgagt cagttcttca aattttactg
      781 catttgcatc tactttcgga tcagcagaat aaacaccgtc tacattgttt ttagccatca
      841 ggataacatc tgcgccgatt tctgccgcgc gtaatgctgc tgttgtgtct gtcgagaagt
      901 acgggttgcc ggtaccgcct gcaaagataa cgatccgtcc tttttctaaa tgacgttctg
      961 ctttacggcg aatatatggc tctgcgattt gacgcatttc aatcgaagtt tgcacgcgtg
     1021 tcggtacacc cacgttttcc aacgtatcct gtaaagctaa ggcattcata actgtagcta
     1081 acatacccat gtaatcagct tgagcacgtt ccatgcccat ttgtgctccg atttgtccgc
     1141 gccagatatt tccgccgccc acaacgattg ccatttcaac gcccagctcg tgaacttctt
     1201 tgatttcttg gatgatttct ttgattactg gtggtttgat tccaaatcct gcgtccccag
     1261 ctaaagcttc tccactcaat tttaagacta cacgctgata tttcggtgtg accatgttca
     1321 ttcctccaat attttctatt gccattttac catacttaga tgatttcgac actctaagac
     1381 tggtttttct tgttttgctt aaaaaaaggg agcgcacaaa ccgtgcgttc ccgtctgtta
     1441 ttcaacagaa ttattttttc acttggctca taacttcttc tacaaagtta tcttcgcgtt
     1501 tttcgatacc ttcgccaact tcgaaacgta cgaatgtttt aacagttgcg ccttttgatg
     1561 caacgtattt ttcaacagtc atatcaggat ctttaacgaa tggttggtcc accaaagcga
     1621 tttctgcttt gaatttcttc aagcgtcctt ctaccatttt ttcaacgata ttcgctggtt
     1681 tgccttcgtt caatgcttgt tctgtaagaa cagttttttc atgttctaat tcagcttctg
     1741 gaatttgtga ttcgtttaca taacgaggat tgatagctgc tacgtgcata gctacgtctc
     1801 ttgcaactgt ttcgtcagtt gttccatcta gaacagtcaa tacggcaata cgtccgccca
     1861 tatgcaagta tccaccaaat gcagcattgt cgtctttttc tacaacttca aagcgacgga
     1921 agctgatttt ttctccgata acttgagttg cttcgatcaa gtcagattca attgtacctt
     1981 tatctgtttt gattttcatt gcagcttcca tgtctgctgg tttgttttca gcaacaagtt
     2041 ctgcaatttc ttttactaaa tcttggaaca tttcgttttt agaaacaaag tctgtttctg
     2101 agtttacttc aacgattgct gcagtgttac ctttcacagc aactgaagcc aatccttcag
     2161 ctgcaatgcg gtcatttttc ttcgcagcct ttgccattcc tttttcacgt aaaagatcaa
     2221 ctgctttttc catgtcgcct tctacttcaa ctaatgcttt tttcgcatcc atcattccta
     2281 cgccagtcat ttcgcgtagt tcttttacca ttttagctgt aacgtctgcc atgtttaact
     2341 cctcctgtgt gtttttcttt ttaaaaaaag ctgcttcaaa ggagagtgag gcttgtcgcc
     2401 cagcctttga aacagctcca tcattcaaaa ttattctgct gaagaattgt cgccttcaac
     2461 aacatctacg atttcttcga ttgatgttgc tgtgttttct tctgtgaaat cttcttcaac
     2521 tacttgatct tcaccttggt ttccttcgat gaaagcatca gccatttttg aagtaatcaa
     2581 tttaacggca cgaattgcat cgtcgtttga agggattact acgtcgattt catctggatc
     2641 gcagtttgta tcaaccatag ctacgattgg gatatttaat ttgtgtgctt cttgaacagc
     2701 aatacgttct ttacgtgggt caacgatgta cattacatct gggattcttg gcatatcagc
     2761 gataccgcct aagaattttt caagacgttc acgttctttg ttcaaaccag caacttcttt
     2821 tttaggtaga acttcaaaag ttccatcttc ttccattgca ttgatttgtt tcaaacggct
     2881 gatacgtttt tggatagtat cccagtttgt caatgttccg cctaaccaac gatggttaac
     2941 gaagtattgt cctgcacgag ttgcttcttc tttgattgct tcttgtgctt gtttttttgt
     3001 acctacgaat aatgctacgc cgccttcttc agcaacgctc ttcatgtaat cataagctgc
     3061 atctactaat ttaactgttt tttgcaagtc aatgatgtag attccgtttc tttctgtgaa
     3121 gatatatttc ttcatttttg gattccagcg acgagtttgg tgaccaaagt gtacgccggc
     3181 ttctagtaat tgtttcatag aaattactgc catgtttgtt tcctccgatt tggttttatt
     3241 tttcctcttc ttatcttcta ccttgccggc aaactttttc aagcacctac cgacaatcca
     3301 ataagaatgt ggatttgctg atgcataaag caccctcagc tattatacag acaaaagatc
     3361 cgtatcgcaa gagcaaatat acttttctgc tcaacattca atagtttacc tgaaagataa
     3421 aaagaattca agaaaaacag tagatttctc tttgtttctt tattatcctt tttccataaa
     3481 ataattttag gtataaaaga cgaatattat tgggcaatcc ttcttttttt tgttatgata
     3541 catgtgaaat ctttcgtaaa ggagaaagaa aatgcgcaaa gctcaaagac atttgctgat
     3601 taaacaagtc attgaagaat tcccgatccg tacgcaagaa gaactattaa acaaacttgg
     3661 gcattatggc gttaccgcca cgcaggcaac gatttctcga gatatccgtg atctaaaaat
     3721 cgtgaaggca cctgatgaaa atggcgtttc ccgcttcgta ttgtttcgcg aaaaaggaac
     3781 tcctgagact aggactgagg aagaggatcg gctggttcaa atgattgaag acattgtatt
     3841 gaaagtcgaa cgagtccact ttttgacgat cgtcaatacc ttgccagaca atgctcattt
     3901 atttgcatct gttttagatg agatcaaacc tccctctatt gtcagtacaa ttgctggatt
     3961 cgatacgatc atggtcatct cggaaaatga ggaggacgca aaacgagtag aagaatttct
     4021 tcaccatcca actgaagtat cactttttta atcagagcac gtattcctaa tatggaatgc
     4081 gtgttttttt attttcaata ttttccttat tgaataaacc tttacactct ttacaaaaat
     4141 acatcatttt ttattcaaat ttttcaacac cttgattgaa tcacaataat catcatttat
     4201 attggatgtt aacaagagca gcttcttgct ctttgtgtat ttcaaaaaag aaatgaaagg
     4261 aaatcatatg tataaattat taacttctgg accattgacg acttctgaaa cagtgaaaaa
     4321 tgctatgctg atcgatcatt gtacttggga tcaagaatac aaagaaatta cacaatggat
     4381 aagaaaaaaa ttattggatc ttgctcaagt atcggaagga atatacacaa cggtcttaat
     4441 gcaaggtagc agctccttcg gggtagaatc ggtattaagt tctgtgatca ggccagaaga
     4501 tactgtactg atttgttcaa acggcgcata tagacaacga atgatcaaca tgtgcgaatg
     4561 tctgaaactg aactataccg tttatgaggt atcggaacat caaatcctcc aagctcatgt
     4621 gattacacag ctgattgaag agaatccgtc tatctccgca ctagcaatgg tccatagcga
     4681 gactacttcc ggtattttga ataatttgga agagattgct gctgtcacac aagaaagaga
     4741 tcttttgttt atagtggacg cgatgtcaag ctttggtggg ataccgattt gtgtagccga
     4801 actagggatt gattttttga tttccagctc aaacaaatgt attcaaggtg ttccaggctt
     4861 ttcttttgta cttgctaata aagcggaact ggaaaaacga aaaaatgtta gccgaagttt
     4921 gtcacttgat ctatatgacc agtaccgcgt gatggaaaac gagaatggca aatggcgttt
     4981 cacttcccct acccatacgg ttttggcttt tcaacaagcg ctgaaggaac tagaggcaga
     5041 aggaggaatc gaaactcgat attcacgtta tctcgccaat aatcatgtgc tacgacaaaa
     5101 aatgacagag atggggttcc agcctttcat tcaagaatat caggggccat tcatcacctc
     5161 ttttctttac cctaaggact ggcgatttga ttttaatcat ttttatcagt atttaaagca
     5221 aaatggattt gtgatctatc ccgggaaaat cagcgatcat gaatgttttc gtatcggaaa
     5281 tattggcgag atctatccgg aagatatttt ggaactgaca gcaattatca aagactataa
     5341 ggagaacgtt aatgattaaa actgtaattt ttgattgggc aggaacaact gtggactttg
     5401 gctgtatggc tcctgtccac gcttttagaa atgcttttct agaaaaagga atccaactga
     5461 ctgacaaaga aatccgctaa ccgatgggaa aattaaaatg ggatcatatc caacagcttc
     5521 tttccctccc ttctgtcaaa aaacaatgga tagctattta tggacaacta cctcaggaaa
     5581 aagaggtgga ggaattgtat caacaatttg aacattatct gtttaaagat ttggtcaagc
     5641 attctacctt gaaacccgac acattggaaa cgatcgaacg gttgagaaac gctgggatca
     5701 atattggttc cacgaatgga tttaatgctc ctatgatgac aatcgtagca gaaaccgcaa
     5761 aaaaagaaag gtattcacca gacttcatgg caacttttga agacgtcgaa gggtatggtc
     5821 gaccgtttcc ttatatgatc cataaaaaca tgcagtactt caaaaacaag tcggttgatg
     5881 aagtaatcaa agtcggagat acggtctcag atatccagga agggaaaaat gccggagtgt
     5941 tgacagtagg tgtaattgaa ggtagttcgc taatggggat ttcttatgat gagtaccaaa
     6001 aattagagat ggggaaaaag atcgtttaaa acagtctgtt gctcttagat tccaacaagc
     6061 cggcgctgat atttgtgtaa acaatttaaa agagttaaca gaatacattt tgtacgctga
     6121 catgaatcca gaatgacttt tatacaaaat aagaggttgt gaaaaagctg tcctgtatca
     6181 agtaataaaa acagccaagc aaaaatagct cctcatattt ttcgtttggt taggcttatt
     6241 accgcagatg caagcttttg aacaccgttt attcgaaaaa aaaaagggag ctgtgacacg
     6301 acttttgtca cagtcccctt atttgcaaac aaacagtgtt taagagacaa cctctccact
     6361 aaacggtgtt cattcagctg actctcggta tttgctcaaa aaacgataaa atttgaaaag
     6421 ctattttctc ttttgtttct ctaatactcg gatcagaacg ctgatttcac attctctttt
     6481 tcttacatct tatctggtgc atgaagtcct agcaaacgaa ggtcttcttt caataataca
     6541 gtcactgcat aaactagagc taagcgtgct tctttttgtt catcatcagc taaaatcttc
     6601 gtatgagcat agtatttgtt gaatgcttgt gctaatttga ttgcatgttt cgcaatcact
     6661 gacggttcgt atttttcccc agcagacaag accgtttcag ggtatttttg aactaattta
     6721 accacttccc agctggtatc gtcattcaat gcatagtctg ctgtttctga agggacaaat
     6781 cctgcttttt ccaacaggct gactgcacga gcatgtgtat attgcacata aggtccagtt
     6841 tctccttcaa atcgaacaac ttcttccagg ttaaagtcaa atgtattcag tcgatcgttt
     6901 ttcaaatcgt ggaaaatgac tgccccaacc ccaacttgtt tagctacagc atctttgttt
     6961 tccaaatcag ggtttttctc gctgatttgt tctttagcag attggattgc ttcatttaat
     7021 acttcttcta ataagacgat ctttccttta cgagttgata attttttacc accttgcgtg
     7081 atcaaaccaa atggaatatg gtgcatgtcg tcagaccagt caaagcccat ttccttcaag
     7141 acagctttca actgtttaaa atgatagctt tgttcattcc ctactacata tagagattgt
     7201 ttgaagtcgt aagtacgttt acggtacaat gcagcagcta agtcacgtgt aatgtatagt
     7261 gtcgcaccgt ctgacttctt aatcaacgct ggattcaggt cataagcaga taggtcaacg
     7321 atctctgcac ctttatcctc gttcagcaaa tgtttttctt ctaaaagttt gacgatttca
     7381 tccatcttgt cattgtagaa agcttcaccg ttcaacgaat cgaaacgtac ttccagcaga
     7441 tcatagattt tattgaattc tttcatcgat tcatcacgga accattgcca taattgaata
     7501 gcctctttat cgccttcttc cagacgtttg aaccaagcac gagcttcttc atttaattct
     7561 ggttctgttt cagctacttc atggaattgg acgtataaac gaagcaattc attgattggt
     7621 tctgctttaa cagcttcttc tgtaccccat tttttgtaag cgacgatcag ttttccaaac
     7681 tgtgttcccc agtcacctaa atggttgatg cggattggct gataaccgat tttttccata
     7741 atgaaaccga tcgaattacc gataactgtc gaacgcaaat gtcccattga gattggtttg
     7801 gcaatattag gagaagacat gtcgattggt actgttcctt gattcccgat gttgctatcc
     7861 ccataatgtt ctttttcttt cactactgtt tgcaaaactt ttttgctgat aagttcttta
     7921 ttcatgaaaa agttcaagta aggtccgaca acttcgattt tttcaaagtt ggcagaatcg
     7981 attttttctg ctaaatctgc agcgatttgc tgtggcgctt ttcggtaaac ttttgctaat
     8041 gaaaaggctg gaaatgcaac atctccgtgt tcagctgatt ttggattttc tagtaattgc
     8101 tcgacttgtt ccagtgttaa atcatctttg acagcgtcat agacagcttt tgcgacaaga
     8161 tctttattat tcatctttat tcctcctaaa gtgttccctt gattgttaaa caaaaaaaat
     8221 ctctagcgac ggcatactta gtatgccatc actagagacg agatttcccg cggtaccact
     8281 ccaattgtcc taaaaaagga ccagctccat ctgatatcgg tagacgaccg tctgtttaaa
     8341 acagaattct ccaagtgcgc ttcgttgtat cttcttcatt cggcttccac cacttccgaa
     8401 ttcgctagcc aagaatgata caagtactct cttgttcaac aaatcttagt cttattaaac
     8461 tttcttgaat tatatcagaa aaaaaaacga aaggctagtc gtttcataaa aaaacaatcc
     8521 agatggccta aaggagaaga aataccacct ggatagctat aaatcatttc gtaaatacga
     8581 aagacttaac aaattaatca gctacgataa tcgttccttc ttcagaagct aaaagattct
     8641 cgatattttc taaagaagtg atgattgcct tagcgtttgg ttttgcttca acaaatgcaa
     8701 tagctgcttc tactttcgga agcatgcttc ctggagcgaa ttgcttttca tcaatgtatt
     8761 gtttcatttc tgaaacagta acagtttcta atttcttttg atctggtttt tggtaattga
     8821 catacacatt gtctactcct gtcaatacga tcagcaaatc cgcatcgatg atttcggcta
     8881 atttttctga agcaaaatct ttatcgatta cggcttctcg tccttctaat ccagtagctg
     8941 tttctacaac aggaatccca ccgccaccaa cagagactgt gataactcct tgatcgacca
     9001 gcgtttcgat gacacgtgct tctttaatcg agatgggttt aggggaagcg actacttttc
     9061 tccatccacg tccagcatct tctttgaatg tcacagtgga gtcagcattc atttgttctt
     9121 tggcttcttc ttccgtgtag aatggaccga ctggtttact tggatttttg aatgaaggat
     9181 cattttcatc cacaataact tgagtgacta aagaaaccac atctttatcg atcccttttt
     9241 ccttcagtac ttcgcccatg gcgttttgta accagtaacc gatagatcct tctgtcattg
     9301 caacacatgt atctaaaggc attgccggtg ttttctcaga atcagcagct tgctgctgaa
     9361 tcaataggtt accgacttgc ggaccatttc cgtgggagat gatcaattca tctccttgtt
     9421 cgataaattt cactaaatac tttgctgttt ccattaacgc ttcttgttgg gcttttgcac
     9481 ttgcatccgt agacaagatg gcattgcccc ctaaagcgac aactactttt cgtttggcca
     9541 tttcattcgt cctttcttca gttctaccga attttctaga taacaaaacg agccagcgtt
     9601 ttgtgatttt ccctcaatgc tgactcgttt tttcgtgaga tgaatgtggt tatgcttaaa
     9661 cgcgagggat aaacaagtta cctaatgttg ctgccatgat cgctttgatt gagtgcatac
     9721 gattttctgc ttggtcaaat tgacgagcat atttgctgcg gaagacttca tctgttactt
     9781 ccatttcagt gatgccaaag cgttctttca tttgttcacc gtaaacagtg tttgtatcat
     9841 ggaaagctgg caagcagtgc aagaagatca aacgatctgt gttgtgtgtt ttttctacca
     9901 tttccatatt gatttggtaa ggtttcaaca atttgatacg ttcttcgaat ttatcttctt
     9961 cacccattga tacccataca tcagaataaa ggacgtctgc tccgtctaca cctttatcaa
    10021 catcgtcggt aatcatcaat tgtgcaccgg atttttcagc aaagccttct gccattttga
    10081 cgatttcttc ttcaggttgt aattcttttg gtgcaacgat acgcatattc gctcctaaaa
    10141 ttgcacctgt gactaataaa gagttagcca tattgtttcg accatctccg cagtaagcaa
    10201 cagtgatacc ttctactgtt ccaaagtttt cttggatagt taaaaagtca gcgatcattt
    10261 gtgttggatg ccattcatca gtcaagccat tccaaactgg aacaccagag aattctgcta
    10321 gttcctctac cattttttga ctgaatccac ggaattcgat tccgtcaaac atacgtccta
    10381 gtactttagc tgtatcttct gtggattctt ttttacctaa ttggatatca tttgcaccta
    10441 gatattcagg atgtgcacct agatcgatcg ctgcagtagt aaatgcagaa cgagtacgtg
    10501 tagatgtttt ttcaaataaa agcgcaatat tttttccttc tagatagtga tgtgggatac
    10561 cacgtttttt caagtctttc aagtgttctg aaaaatcgat caaatattgt aattcttctt
    10621 ttgtaaagtc tttttctgct aataagcttc ttccttggaa tactgattct ttcatattaa
    10681 acattctcct ttagattgtt tttatttaag attaaagagg aaatcccgac ggcagctgac
    10741 agtaagactg ccgtcaggaa acaaattact tcaagtcttc acggacaagt ggttggctca
    10801 tgcagcgtgg accaccacga cctcgtgaca attcacttga attgatttct aacactttga
    10861 tgccatagct acgaagcaat tcgttcgata cataatttcg gttataagtg actacaacac
    10921 ctggagcgat tgccaatgtg tttgatccat cattccattg ttctcgaggt gcaacgatct
    10981 catctccatt accagttggg atcagtacaa gatcatctaa tccaagagca gctttcatcg
    11041 tttcgtgtaa gttatctgaa tgagtaatct tgatatcatc accatctggt tcgattgtaa
    11101 agacatccat cttaccgtct ttactttgaa ttgctggatg gatagtgaat ttatcgtgat
    11161 ctaccattgt aaatacggta tccaaatgca tcattgcacg gttgttcgga attttgattg
    11221 ccaacacttt ttcaaatcct gaattttttg cgaataggtg gcgtgctaat ttttctaaag
    11281 ctttcgcatt agttcgttga gaaatcccaa cagctactac tttatcgctt aagatcaatt
    11341 cgtctccgcc ttcgatatga tctggatttt cacgatccaa ccatacttcg attcctttat
    11401 ttgcaaatct tggatgatgt ttcaaaatat attctgtaaa catcgattca cgacgacgtg
    11461 cttcaaaagt catcttattg actgtcatcc catttcccat tgatgcggaa gggtcgcgtg
    11521 taaagtacaa gtttggcatt gggtccatgt aaaatggata gtcatcgtct gctgacagat
    11581 catatagact gctagaacgt acttcgatat cttttgtacg aaccccagcc atgattttat
    11641 ctaccatttc ttgcgtttcc attgatagaa ggaactcatg aagaccctct cttacagcat
    11701 tcgatgcaat atgagattca tccaacattt tattcaagaa ttgttctttg acattgcctg
    11761 cgtcaatcgc ttctgccgct aatttttcca agtaaagagt ctcgacgcct tcattttgca
    11821 atgtcttcgc aaagttgtca tgttcttctt gagcaatcgg aagatatgga atatcatcga
    11881 acaacagacg atccataata tctggtgtca aattttccac ttcttgtcca ggccgtttca
    11941 gtaaaactgt ctttaatttc cctatttcag agaaaacgtg aataggttta tccatgttgt
    12001 gttgcctcct tctttttgat tacatgtata ggatatcctc cttttgtaat cactttcata
    12061 attttgtctc attcaaaatg agacattcct cacattaata ttcgataatt aaataattaa
    12121 acgtttttct atttttaagc gtaatttatt
//
LOCUS       DAFTHM010000079        11857 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFTHM010000079 DAFTHM010000000
VERSION     DAFTHM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.079"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            12..1646
                     /locus_tag="L7C88_002097"
     CDS             12..1646
                     /locus_tag="L7C88_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558906.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(1913..3082)
                     /locus_tag="L7C88_002098"
     CDS             complement(1913..3082)
                     /locus_tag="L7C88_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBP9558907.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            3286..4461
                     /gene="mltG"
                     /locus_tag="L7C88_002099"
     CDS             3286..4461
                     /gene="mltG"
                     /locus_tag="L7C88_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBP9558908.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            4597..5076
                     /gene="greA"
                     /locus_tag="L7C88_002100"
     CDS             4597..5076
                     /gene="greA"
                     /locus_tag="L7C88_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBP9558909.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            5245..5976
                     /locus_tag="L7C88_002101"
     CDS             5245..5976
                     /locus_tag="L7C88_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBP9558910.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            5973..7040
                     /locus_tag="L7C88_002102"
     CDS             5973..7040
                     /locus_tag="L7C88_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBP9558911.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            7047..7679
                     /locus_tag="L7C88_002103"
     CDS             7047..7679
                     /locus_tag="L7C88_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9558912.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            7819..8484
                     /locus_tag="L7C88_002104"
     CDS             7819..8484
                     /locus_tag="L7C88_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBP9558913.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            8512..8805
                     /locus_tag="L7C88_002105"
     CDS             8512..8805
                     /locus_tag="L7C88_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBP9558914.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(8873..9820)
                     /locus_tag="L7C88_002106"
     CDS             complement(8873..9820)
                     /locus_tag="L7C88_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBP9558915.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(9998..10801)
                     /locus_tag="L7C88_002107"
     CDS             complement(9998..10801)
                     /locus_tag="L7C88_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBP9558916.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            10947..>11857
                     /locus_tag="L7C88_002108"
     CDS             10947..>11857
                     /locus_tag="L7C88_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBP9558917.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDES"
BASE COUNT         4012 a         1802 c         2274 g         3769 t
ORIGIN      
        1 tataaaaaaa catgaggtgg tatatgaatt tgaaaaaaat tttttctgta aaaatattta
       61 tagtttatgc atttgttagt ttattatatt tatttccagc atttaaaaac atggaaatat
      121 ttggctttta tgatacggca tttcacatta atcgtgcgtt aagtttagaa tctattttta
      181 gctcccctat taattttgaa acgtttagat catatggcat gcaagtaaat aatttttacc
      241 catggttaac tctatatcct ttatttttat tgatcaagtt tactaattta gcaataggct
      301 ataacctttt tctttatatt gttacgctca ttactctatt tatatgtcat tatgtaatgt
      361 atgaaattac caaaaaacat gttactagct cctttttcgc tattatatat acaacatctt
      421 cttttaggag tgtagaaata tttcttcgag gggcaatggg ggaattactc gcaatgtcaa
      481 tacttcctct tattttactc gggtttataa agctttacga ctcaaaaaaa gaatcttggg
      541 ttatgttggc gattagcatg actttattaa tttacactca tgttctttct gtagctatga
      601 ctatggtaat gattataatt gctttaatta ttcaatttta tcggaaaaag aaaatagaaa
      661 tcttcttaat tattaaatta ataaaagctg ctatagttac tttacttctt tcactagcgt
      721 ttataggtcc tatgattgag cagacattgt atcaagatct gaatagacct tatgtggata
      781 tattacaaaa aagagcaatt tatctgggta aagagttttt gattggaagt atagattcag
      841 aattactatc atttggtatt ggcttaactt tgcttatttg tttaattata ctaacattta
      901 actttaaaaa attaggaatc ttatctaaaa tcacttatat aatgggtata atatctattc
      961 tactttgtac aaaaatattt ccatggtttg ccttacaaaa tactccttta aatattattc
     1021 aagctccttg gcgttttatg atattttcaa cattgttcat atctttttca gtatctctat
     1081 ttatttctcc acagttggaa aaattttctt atacaaggag aagaaatttt atactattat
     1141 taatattagc tatttcaatt ttaaattatt catcagtagt taacatggtg aaagaaatga
     1201 attttcaagg aacttattct aatgaacaaa tggaaaataa acttgaagaa tttgagaatt
     1261 ttgattatgt acctataggc tataaaaaag atcaattgct tttgaaaaac catcaagtta
     1321 cagaagatgg tcaagttatt tatagtagct tttctccaaa taaagatgaa attacattta
     1381 cgtttaaatc ttcaaaaggc aaaacaatag ttttacctgt attccggtat aaaggattaa
     1441 cggttactgt taattcaaaa aatgctacag tactaaaaca aggaggtcct tttgttacag
     1501 taaaaagtga aagtggaata aataaagtaa caatcaggta ttcatacaca tttttttcta
     1561 aaatctcatt atttatttct ataatcacgc taattgttct tcttttttat tgcataaaat
     1621 taaaaataag aacaagccat gaatgatttg ctagcacata ttttagcaat ctaaagatac
     1681 tattttagat ttaataggcc ctttgtcaaa taatgttggt aaagagaaat cttagaataa
     1741 tttggacaga acagaaagaa gaacacctct ttctgttctg tttatttgga attaaagtct
     1801 gtagcaaaaa ttgattttta gatttgtccc acactctttc ctacgtttag tcgagtactt
     1861 tttttaagca aatgctattc aaagaagtag tatttgctat cttttcatca tatcagctat
     1921 ttgccaactt agtagttcct tccatcaggt catagatttg gtttcttaga tcagcagtag
     1981 gcagtttgat agttttgtca gcttttatat tgctttccat gatgatagca tcctgtgaat
     2041 ctttgctaaa tatagcagat gtatcaaaag agtcgatatt tccttgcgac aggatataat
     2101 tatctccgct atatacccca ccactatatg gatgtccatt cgcattttca cgccataatg
     2161 agaagagtaa gtctttggaa actagttttc cagataaaac ttgtgtaaac agcgtattta
     2221 aatcatagac ggacatactg atattaccag tccctaattc gttatggatc tctgtttcag
     2281 attctgtcag tggtttaaag taatcatcct ctttagacat ttgataggat agtgcatgat
     2341 tggatgaatt tttgacttgg tcataaaatt ttgtatgctg taatcctaaa ggttcgatga
     2401 tatcatcggt caataatttt tcatacggtt gatttgttaa tttgatcaaa attccagtca
     2461 atatggtaaa gttcaatgaa tcataatgag aggtctgata atctgtaaat tttaagtgct
     2521 gaatcgcaaa ttgaacgact tcttcatcag tcatcggtat ggttggagaa gcagttcggt
     2581 gcaagcctga gcgcatatac agcaagtcac ggatagtaat ttgctggctg ccagcaattt
     2641 gtggatagaa ttgagccagc ttagtatcta aagaaaggtg cccacgctcg acttgtttta
     2701 aaatcaaaag agtagtcaat gctttttgaa ccgaaccaat ctgataataa agagaaggat
     2761 catttggttg ttgcgtgagt ttattcgcat agccatagcc tttttccatg atgatgcgat
     2821 tatttttctt tacgtaaatt gagccaatat aatcattttt tcttaatagt tgatcgattt
     2881 tttcaacgag ctgttgttca ttggtagtca gtatcaactt tttttgagct gattgagcat
     2941 gggcaactat ctgagagtgt tcattattgt aaaattgcca tccaagaata gttcctgtag
     3001 agaacgcact aaggctaaac aacacgacaa cgatcattaa aaatgaatat tttctttttt
     3061 tagcatgttt tccttttttc ataatagttt atttagtctc ctttcttttt tacagaaaga
     3121 ataaagctaa aatagcttgt atcttgataa catttatttt aatcttatag taatggattt
     3181 actacttaca tttttgatag aatatttaaa taaaatcatt cacgccaatt caaatatcat
     3241 gtataatgaa taaagttacg aacttgatag taaggaggag ttgttttgtc aggaaacaaa
     3301 caacacccaa gtaaagataa aaaagaagcc agtaaggcag ctacagcaga tataatcgac
     3361 aagcggagaa atctgcgtaa aaaagaagat aagattgtga ggaagatcat tttagtgatt
     3421 gctcttacat tattgattat tggcggattt cttggattta ccgtgtatcg ttatgtagat
     3481 agcgggttga agcctttaga taaatcagat gaccaattag tccaagtcga gatcccgagt
     3541 ggctcttcta acaagcagat tggtgagatt ttggagaagg acaatattat taaaagcggg
     3601 attgttttca attattatac aaaatttaaa aatttaactg gctttcaagc tggctattat
     3661 cagttagcgc ctaatatgac tcttgacgag attggcaaac agttgcaaga aggcggtact
     3721 tctgagccaa caaaagttgc agatgggaaa attgccattc cagaagggta cgatatcgat
     3781 cagattgctg aacgggtagc gaaggtaact ggtaaagaca agaaagaatt tttagattta
     3841 gtgaatgatg agactttctt taacgagttg caccaaaaat tcccagaact gttggaaagt
     3901 gcatctaaag ctgagaacac aaaataccgt ttggaaggtt acttattccc agccacatat
     3961 gattattaca cgagtacttc gcttaaggat ctagtgattg aaatggtgaa caagacgaat
     4021 acggtcatgc aaaactatta ttcagctatc aagcagaaaa atttgactgt acaagaagtt
     4081 ttaactctag cttctctagt tgaaaaagaa ggcgtaaaag aaaatgatcg taaaaacatt
     4141 gcacaagtct tctttaaccg aatcaaagca aatatgccac ttcagtcaga tatctctgtt
     4201 ttatacgcat taggtgaaca caaagaatta gtgacgtatg aagatacagc tgtagattca
     4261 ccatataatt tgtataccaa taccggctat ggacctggac cttttgacaa tccaagcgaa
     4321 gaggcaatca aggcagtatt agaaccagca gaaaatgact attattattt cgtagcagat
     4381 acgagcactg gaaatgttta tttcgctaaa acttatgaag aacatatgga attagtggaa
     4441 aaatatgtaa ataattctta gaaaaacagg ctctagacat tgatcatttt tagaaaaaca
     4501 tttacatttg aagaaaagcg tggtaatctt ttttggacta tattcctcaa aagattacct
     4561 tttgcggtat tttatcgaaa aaaggagacg ttacacatgg tagagaaagt ttatccaatg
     4621 actctagaag gtaaagaaaa attagaaaaa gaattagaag aactaaaaac agtcaaacgc
     4681 ggagaaatca ttgaacgaat caaaattgcc cgcggtttcg gagatctttc cgaaaactct
     4741 gaatatgaat cagcgaaaga tgaacaagca tttgttgaag gaagaatcac aacaattgaa
     4801 aatatgattc gttttgctca aatcatcgat aacgacggtg tagatgcaga tgaggtatca
     4861 attggtaaaa cagttacatt catcgaacta ccagatggag aagaagaaga gtacacgatt
     4921 gtcggaagcg ctgaagcaga tccgttttct ggcaaaattt ccaatgattc tcctattgcg
     4981 caagcattga ttggcaaacg taaaaatgat gaagtaacta ttgctactcc aggtggcgat
     5041 atgttagtta aaatcgtcaa agtagaacaa gcgtagtctg actgaaagat ctagagagtt
     5101 catcttactg atgatacact ctagatcttt ttctctttgt gtattttaga tttcaacaaa
     5161 cgatcttaca tctaaagtcc tatagccaac agttaaaaaa ataggtatga tgaaatgaga
     5221 atgtgtcagg agggagaaag agcgatgaat agttcttggc gtttttttgt ggtagttgaa
     5281 gcactactgc tgttatttgc tgtttggcaa atcgtaaaca atactggact tttgctttta
     5341 gtgatattcg gtattttcaa tatatatcta gctatgcgca aacatcctcg tactaaattt
     5401 caaaattttc aattgatatt aggaagtttg gtcatttttt ttagcttagt caacagtcct
     5461 gctttatgga tgatggctgt atttgccgtt ttatttattg gtctgaaagg tgtagagatt
     5521 tcagggatag atttaaccaa aaatgctttt tggcgaaaga aacagatcat gatgatccaa
     5581 acagagcaat taaaaacaca taataatgag cggaaaagac agcaattatt cggtaaccaa
     5641 cgtattggaa acgacgtcta tgaatgggac gatatcaaca tcgccgtcat ttctggtgat
     5701 actatcatag atttgggcaa tacgcttttg ccaaaagatg ataatattgt gattgtaaga
     5761 aaagggatag gcagaacacg gatcttagta cctttgggcg tagccatccg attagagcat
     5821 gcgacattag taggaaatgt cttgtttgaa gaagagcaat tttctttgaa aaatgaacaa
     5881 atcaaaatct acagcagtga ttatgatgaa aaccctcgta gattgaagat tattactaat
     5941 accttgattg gagatgtcga ggtgatacga atatgatggg aaaaatatcc agagcgatgc
     6001 tagctgttta ttcggggatt gcggctttcc ttattattct attttcactt ttcacttatt
     6061 tttatgccag caatcaaagt cattggtggg gagaattact gcgtgcacgt ttattatatg
     6121 ttccgcttat cttccatttg ttagccattt ccttaggtgt aggattaatt gtctttctat
     6181 tattatcact tattcaaaag acaaaatacg ggaaaatcga agaaaagctg cgtgcacttt
     6241 cttctggcaa ttatgaatcc aaattgttgc ttcttccgat cccaagtgca tcggacgatt
     6301 tatacatcaa agatattgat aaggaaatca ctaagataaa agaaaaaatg attgaagtat
     6361 ctagtgaatt acaaattgta acgagccgtc cccaatatgt agatggacaa accaaagaag
     6421 aaattttaga attagaaaga catcgattag cccgtgagct gcatgattca gtttcgcaac
     6481 aattgtttgc agcaatgatg atgatgtcgg cattgacgga gcaagcagaa aaaagcgaga
     6541 caccagaaat gtttcgcaag cagttgaaaa tggtagcaga gatcatcaac gcttcccagt
     6601 ctgagatgcg tgcgctgctt cttcatctac gtccagtcaa tttagaagag aaaagtttaa
     6661 agcaaggtat cgagcagtta ttgaaggaat tgcaaaataa aatccagatt tcgctgaaat
     6721 gggatgtaga agatgtaaaa ctatctagtt ccattgagga tcacttgttc cgaatcgttc
     6781 aagaattgtt atcaaataca ttaagacatg ctaaagccaa tgaattagag gtatatttgc
     6841 acaaaataga caataatctt ttgttacgta ttattgacga cggaacaggg tttaatatga
     6901 atgaaacgaa aacgggaagt tatggattga acaatatcaa agaacgagta gctggtattg
     6961 gtggaacagt aaaaatcatt agttttaaag gtcaaggtac aagtgtagaa atcaaggtcc
     7021 ctttgatgaa ggaggcatag ataaggatga taaaagtttt attagtagat gaccatgaaa
     7081 tggtgcgctt aggcgtctct tcttatttat ctattcaaga agacattgaa gtaattggag
     7141 aagctgaaaa tggacgacaa ggctatgaga aggcgatgac acttcgaccg gacgtcattt
     7201 taatggactt agtcatggaa gaaatggatg gtatcgaatc aacaaaagca atcttaaaag
     7261 attggccaga agctaaaatc attatcgtaa ccagttttat tgatgacgaa aaagtttatc
     7321 ctgccattga agcaggtgca gcagggtatt tgttgaagac ctctaccgca catgaaattg
     7381 ctgatgctat aagggcaacg caacgtggcg agcgagtatt agaaccagaa gtgacaacaa
     7441 aaatgatgga aaaaatgagt cggcgaaatg agcctgtatt acatgaagaa ctaacgaatc
     7501 gggaaaatga aattttaatg ctgatttctg aaggaaaaag taatcaggaa atagcggacg
     7561 aattgtttat tacactgaaa acagtaaaaa cacatgtttc caatatattg gctaagctag
     7621 aagtggaaga ccgtacacaa gccgctatct atgcattcaa acatggtttg gtgaaataaa
     7681 aacgatgata aagaggataa tcaaaagctg agaaaataac tattattttt cttggctttt
     7741 ttacaataat gatgcttgct tttgtttttg taaaggcttt gttatactga gaaaagaaga
     7801 tactaaagga ggaaaacggt gaaacaaaat tttgcaattg taggtcttgg acgatttggc
     7861 ggaagtatct gccgaacact gatcgaagct ggtcaagaag tactggctat tgatagtaat
     7921 gaagatcggg tcaatgaata tatgaatata gccactcatg ctgttgtggc aaatgcacag
     7981 gatgaaatga cacttcgatc attaggcata agaaatttcg atcatgtaat tgtcgctatt
     8041 ggagaagata ttcaagccag tatcttagtt actctgatgg taaaggaaat gggcgtacca
     8101 aatattttag caaaagccca aaatgagtat catgccagag tacttgaaaa gatcggagct
     8161 gatcgcgtcg tccatcccga gcgagacatg ggaataagga ttgcgcataa tttagtgtca
     8221 aagaatattt tagattacct agagttgtca gataaatatt ctttagcaga aatccgagtc
     8281 tccaatccta aatttttcaa caaaacatta gctgaattaa atttcaggca acgttttgac
     8341 ttaacagtag tcgccatacg aagagtagat caaacggtta tcgcttctcc tgcagcagat
     8401 gaatatgttc gtgaaaatga taatctactg gttattggag agacaggcga tgtggatatt
     8461 ctagacgata agatgaatca atagaaagaa aagagaaagt aggttgttgg gatgaaatta
     8521 acggtaacgc caaaagcaca aaagtggttt gactcagaaa ttgatctgcc agaaacttac
     8581 ggaatacgtt tttttggaaa agtctacggc aaaacagagg ttcatgatgg tttttcgatt
     8641 ggaatgtcag ttgaacagcc agaacatcct gtaaagaaag tggaaatgga tgggacactt
     8701 ttttttatcg aggaagcaga tgaatggttc tttaaaggat atgatttact tgttgattat
     8761 gatcccaacc tggaggagcc aacctatcac tttaaaaaac aataaaaaaa gagagggtga
     8821 cacaattttt gtcaccttct cttttttctt ttgaaaatat tgttttcagc tattaatatc
     8881 ctgcagacaa ttttacttga ttggtttgaa gctcatgggt ggcaaagtag cttttcagat
     8941 tggttaaaaa aatagccatt aatttctttt gaaaatcagg tgtcaaacct gcaatgtggg
     9001 aagtaatcag tacattgtcc attttccaaa gaggatgatc ttgtggaaga ggctcttcct
     9061 caaaaacgtc taatgctgca aaggaaagtt gctggttatt taaagcctgc accagatctt
     9121 gtgtcttaac agaagcacca cggccaacat tgatgaatac agattttgga tcaaagtgtt
     9181 caaacatatg ctgatcaaag agcccagttg tttcctccgt tagaggtaag atattgacta
     9241 cgaaatctac ttcaggaaga acttccttta gttgatttaa agaaaaagtc ttttccattc
     9301 cttctgctgg atgaccggat gtattgattc catagcagtt catgtctaat gctttgcatt
     9361 tttttgcaat catttttcca atatggccag ttccaatgat tagtattttt ttcccttgga
     9421 tagattggta atggaccgat gaacctaacc atttcatgtc actctgtgcc ttttgtgctt
     9481 gaaaaagacc acgagaatac ccaaggatga ttcctaagac atgctccgta atcgattcac
     9541 tgtggatgcc actaccattt gaaagtaaaa tatgtttctt tgaaaaagtc tcaaggggta
     9601 gctgatcaac accagctgag atagattgga cccatttcaa ggtagaagag gctaatagtt
     9661 tttcttggta gtctgagttc cagcccaaac tgatctctac attttgtaga tcctctggtt
     9721 gtaattctgt tttaaagata taaccaggcg ctatagtatg gatttcttcg ataaattcat
     9781 cacgaaatgg acgatctgca taaatgattc tttctgacat agttaatttc ccgcctttct
     9841 ttactctaag tgtagcgcat acaagaagaa ctttgaagcg ccttgcttgt tttttgagaa
     9901 agaaatattt ttcaaataaa aaaggggctg tgacaaaaaa atgtcacaac ctctaaaagg
     9961 gtctattgaa gtagaaataa cgagttgtct ttatttctta attgatcgat atttttgccc
    10021 atcctttgac agcttgagca aaaataaaga ttcctgcaaa agcaatgaag gcgctagtgt
    10081 caaaagaagg aagaaagacc atcaagattg ttgcaattat agtaggcaat gaaattgaat
    10141 agatcaatgt ttttaaacaa tcaagaaaag tagcttttgt tagtcgaaag cgtgcataga
    10201 gaaaagcagc aatgttggta aatagcaaag tgatcagcag attcagaaaa ctaggataaa
    10261 tagaaaatat aaatgtcagg acttttatcc aaagtggtat agatgcttca cttaaaaaag
    10321 aacggagctg cttacctgtt aagtttttta aagattcatt ggtgtaggga agttctaatt
    10381 ggttattgtt caacaaagca gaagtcgtgc ctgtattagg aagagctatg ataagtttgt
    10441 tttttaacat cccgacacta acaaaattcc ccatcaaatc agtagagatg tcctgttctg
    10501 ttcgttttcc ctctggatca aatgtgaaga taatggagtt tgtttggtaa atgaatcctt
    10561 ctttttcttc ggtttgaagc tgcccgtttt ggattgtaaa atcaggaatg cgagtagcaa
    10621 tcttttgccc atccaattga atgttgttta agacttgaaa aacttgaaaa gagattggca
    10681 aagccataat tatactcaaa actaaaagat agacaatggc tttccaaaat gggacatttc
    10741 tcgcctcctt taggtctttg aatcgtataa aggaactgat aattaattgt tttgttgtca
    10801 taagtactcc tcatctagta gtgtcatcac ttgcaattct agcgaagtat caagtgaaat
    10861 acaagtgctt taaggaaaca gctgaatgat tggtgaaata tcaaaaaaat gttattcttg
    10921 tctaaagact atccaatata aataaaatgg aggaaggaat agtgcctaca cagccacaga
    10981 gatcatcaaa aaaactattt ggagtagtgg ttttgaatgc ggtgatcact ttatcagaat
    11041 ttattggagg gattatgtca gggagtttgt ctcttgtttc agatgctttc cataacctta
    11101 gtgatacatt ggcaattatt ttttcttacg gggcacaaaa aatggcccga aaagaagcaa
    11161 ataaaaaacg tacgtatggc taccagcgtt tagaaatatt gagtgctttc atcaactcat
    11221 tcatattgat catattatcc ttgtttttaa ccgttgaagc attcaagcgg ttcacttcac
    11281 cagaaaagat aaatagtcat ttgatgctaa cagtagcagt tattggattg ctcgcgaatt
    11341 tgttctcagt attattatta cgacaagaag cagatgaaag tttgaatata aaatctagtt
    11401 atttgcattt gttaagtgat acactgtctt cggtaagtgt gattatcgga gcaattttga
    11461 tccgtttttt cgatatctac tggatcgatc cagttattac actgatcatt tcgatatata
    11521 tattgataga agcgataatg gtgatcaaaa aagctgccgc tattttgata caaagtgcac
    11581 ctgctatcga ctatgaaaaa atggaacaag aaattgaagc aatcgatggg gtaaaggatg
    11641 ttcatcatgt ccatatttgg cagtatagcg aaaagataat tattttcgac ggacatattg
    11701 attttgaaga tcagctacta agcgagattg aaaagatata tcctcgtata atttctttat
    11761 taaaattaaa atatggtatt acacatgtga cgatccaagc agagacaaag gcaaaggatc
    11821 aaaaaaaatt aattttttta aataaagatg aaagtta
//
LOCUS       DAFTHM010000080        11669 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFTHM010000080 DAFTHM010000000
VERSION     DAFTHM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.080"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(38..217)
                     /locus_tag="L7C88_002109"
     CDS             complement(38..217)
                     /locus_tag="L7C88_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558918.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(598..1305)
                     /locus_tag="L7C88_002110"
     CDS             complement(598..1305)
                     /locus_tag="L7C88_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558919.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
     gene            complement(1298..1735)
                     /locus_tag="L7C88_002111"
     CDS             complement(1298..1735)
                     /locus_tag="L7C88_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558920.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
     gene            complement(1750..2001)
                     /locus_tag="L7C88_002112"
     CDS             complement(1750..2001)
                     /locus_tag="L7C88_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558921.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            complement(2001..2207)
                     /locus_tag="L7C88_002113"
     CDS             complement(2001..2207)
                     /locus_tag="L7C88_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBP9558922.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
     gene            complement(2644..2904)
                     /locus_tag="L7C88_002114"
     CDS             complement(2644..2904)
                     /locus_tag="L7C88_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558923.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            2979..3182
                     /locus_tag="L7C88_002115"
     CDS             2979..3182
                     /locus_tag="L7C88_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBP9558924.1"
                     /translation="MIKTVKFVTVAIRLKVRWCVCAYFQNLTERRSLLPVETALGLMI
                     SFGSLIATIIFGILAVVNNNQKK"
     gene            complement(3323..3808)
                     /gene="ssb"
                     /locus_tag="L7C88_002116"
     CDS             complement(3323..3808)
                     /gene="ssb"
                     /locus_tag="L7C88_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBP9558925.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(3811..4710)
                     /locus_tag="L7C88_002117"
     CDS             complement(3811..4710)
                     /locus_tag="L7C88_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBP9558926.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            complement(4723..5316)
                     /locus_tag="L7C88_002118"
     CDS             complement(4723..5316)
                     /locus_tag="L7C88_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBP9558927.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            complement(5392..5541)
                     /locus_tag="L7C88_002119"
     CDS             complement(5392..5541)
                     /locus_tag="L7C88_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558928.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            complement(5557..7761)
                     /locus_tag="L7C88_002120"
     CDS             complement(5557..7761)
                     /locus_tag="L7C88_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBP9558929.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            complement(7772..9232)
                     /locus_tag="L7C88_002121"
     CDS             complement(7772..9232)
                     /locus_tag="L7C88_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBP9558930.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQERE"
     gene            complement(9293..11665)
                     /locus_tag="L7C88_002122"
     CDS             complement(9293..11665)
                     /locus_tag="L7C88_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558931.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
BASE COUNT         2892 a         2433 c         1958 g         4386 t
ORIGIN      
        1 gtgctatcac ttttagtttt taggataaaa agtgacgtca ctttttgagt gctggtacct
       61 caaatcctgc tttttcttgg gcaatcaata aatctaacgc aatacacata atcctggatt
      121 cacttttgcc gtacttctgc tttagttgct gcaattcttt ttgtctcttt tcatccaacg
      181 tcacgggtaa ccgtttattt cctattgcaa ttggcattag tactctctcc tttcatcgaa
      241 ataaccctat taaaaatatg gctgcaatca acttgaatat tagactcaca agggttaaca
      301 caaagcgcca aaagatcaaa caaaatacca gtattcctaa gaatactacg aagtttaaat
      361 gtagagctgc accatgacgc ataagtatct cgccaacaaa cagtacgaac aatagaggaa
      421 tgattttatt catatggatc tccttctttc tcttaggtta tcgggctttg cccgcttatt
      481 tcgcaccacc taagcggcgg gggcggttgg atcgattggt gcgaaataag aaccattccc
      541 ttaatttcaa ggttttttgt tcttatttca cacatcctca cttttcggta taaatggtta
      601 ttgacctttt ttcctttcaa atcgttgata tggcattcgt ttacggtcaa gttcattttg
      661 gatttcttct gtatcgtcgt aagtgtaggt gtctaaaaaa tcagttaaag tcgtgtacca
      721 gtcgtcgcct gggttatcta cttcttctac atattccctc aaaaatgctt cgggtacagt
      781 gagttcataa tccattccca ttaacacgat agattccgtc ccacacgtca aaaatctagt
      841 aaatacaagg taataatcgt ctaccgtcgc atctttgctg tttagctctt ccatttcttc
      901 ttccattaat tccatgctct caaaaattga ataatattct gattctgagt aatagtgttt
      961 cctgcaaatc gtgtagctga caaagttttc gaccagctca ctcctttcta ggtaaacatt
     1021 catgatatat ttttctgttt ctagtcgtag aagctccgct ccttttttta atgtgtcagg
     1081 acgacgttta tacacgtcta aacgattatg gctgactgta accttcgttt gactcgtttc
     1141 actttccata tacaactgtt cttccactct ttgaataaag tacttcattt cttccataca
     1201 actaaagtct ttttgaatcc gtctgattac ttcattcaag tgttctttgt ttgttaaaaa
     1261 ttgcgaaaca tcttctgttg ttagctgata aaccacctta ttcattatct ttctcctccg
     1321 attcaatcgt ataaaatgca ccattttttt cgatattttc aaaagtatct agccagtcgc
     1381 tagccattgc tttagctttc ttaatctgtg cgaattttgc ataagtcagt tctaaggctt
     1441 gatattcgga aggtttgata gtgcttggtt tgacacctac ttccaagcat agtaaggctt
     1501 ggaaaaacca ttttccattt tgttttttca gttcttccag tgttcgatag tacgtcgcaa
     1561 tgagattcat ttcgacacct gattcaatca tttcttccac tgcgactgac aatttttcct
     1621 tgtaatgttt tttgggtaca cgtgtttcat ggtataggaa cgtcatatcc tccatttttt
     1681 gtgccatttt atccaaaggt aatttgacaa attcgtcata gtaattttga gccatatttt
     1741 ttctcctttt tagttctcta atttggttaa ccaatattcg atttcataag tttccatgtt
     1801 ttcttgataa tgcagttcat atcctgcaat cttcactagg tcttcaaata gcatagtcgg
     1861 tgcatcctct actaaagggg tttctatcgt ccagtaccgc ggaataagta aagcttctgc
     1921 tactttttca gaaatgactt ctttgtccac caaaatttga acgacttctt ttacagtcaa
     1981 taatttgtgt tgtgttttca tcaccgtttc tttactttct catcaatcaa aacataatcg
     2041 ccataagaca aggtatattt tttcccgcat gttggacatt gatacaaacg atagcttttg
     2101 atacatttcg ctctttctcc acaatcgcat tcgacagtat gtggtgcatg atagtttggg
     2161 aataattcgc tgaagggaac accccaataa tcaaatttct ttcgcatgat tgattctgcc
     2221 tcctcttagg aaaggtttta tttcctttcg ttagttcttt ctttattgat ttgttggcca
     2281 gaatgaatca acgaaaagcg acaaggacaa gggcgcgcag cgtgccattt acccttgtcc
     2341 ttgtcgcttt ttggtgataa aaggcaactt gttgccggtc tggcaaatca ataaagagat
     2401 agcgaacagg aacgaacctt ttggtgagag gaagtttttt ctattttgtc ttgctttgca
     2461 agacaccata tcttagtgaa cgtgcaacgt tcacttcctt tcttctcgaa cggcggtggc
     2521 ggttggagtg agagaaaggt ttttcaattg agaaggcact tgtgtcttcc taaaaaggtc
     2581 ttttcctgtt tctatgtaaa acaaaaagag ctgcaatcct catttaggac tgcagctctt
     2641 cttttatatg cccatcgatc gcgtaaaatg atcggggttt ctaatttgca tcgattcaat
     2701 gactaattga ttccgtttat tgaaatgacc tgtgacggca atattgtatt ttccatcatc
     2761 cataattaac aatttatcga taatttcaat atctgcaact acacaattaa tcgattcatg
     2821 aattgtttgt aaagtaaagc gaaccaataa tggttgtgtt tttattactc ggattttatc
     2881 aagcaaacca acatatttgt tcatcacgat cacctcgcta aaattatagc aaaaacagct
     2941 aaaattgaga atttttattc gattttagat atgctataat gatcaagaca gtaaagtttg
     3001 tgacggtggc tatccgattg aaagtgaggt ggtgcgtatg tgcgtacttc caaaatctta
     3061 cagaaaggag aagccttttg cctgttgaaa cggcgctagg attaatgatt agtttcggtt
     3121 ctttgatcgc aacaatcatt tttggaatct tagcagttgt aaacaacaat caaaaaaaat
     3181 aaccgtcagc tttagccggt cgacgattat ttttcaaaaa taatattaag ctggtcaccg
     3241 tcttaaacgg tgctgttagg ggagttgtta gcgcaactcc tcttttcgta tccattataa
     3301 caactttatt gatcttttac aatcagaatg gtaaatcatc atcactaata tcgattgatt
     3361 gtccgccaaa tggattttgt gaagcgttca atccattgtt gttaggcgta gctacatccc
     3421 gttgttcaaa ggtggtaggg cttggactgc tggacgattg atcagcgtgc gcacggcttt
     3481 ctgtcgctgc tttactttct aatagttgga aattatcggc cacaacttct gtcacataca
     3541 cacgttgtcc ttgttggtta tcgtaggttc gggtttgaat ccgtccaaca acgccgatca
     3601 aactgccctt tttagctaat gtcgccatcg tttctgctgg tttgcgccaa atcacacagt
     3661 taataaaatc agcttctcga ttgccgtttt gattcgtgaa atttcggttg acagctaggg
     3721 taaaagtcgc tactgcagta ccactcgcgg tataacgtaa atctggatct ttggttaagc
     3781 gtcctactaa agttacatta ttgatcatct ttatctctcc atttcttgat tcatttgttg
     3841 tgatctttta aactgccgtt ttctttcttg attttcaatt ttgatcacac ttttcattag
     3901 gtgatcaatt tcgttgactg tatctgtaaa tgaaatggaa ttcgcaaacg tgttaactga
     3961 gcgatatttt tcccactgct tttccaaata gtcatttcct ctgatcttat ccatttctct
     4021 ttcataataa aaggacaacg gttttgtatc cccacgtttt gtaaatgtat ttcgaacact
     4081 tttgtataac tctttcgtat cgatattttc tagtttcgga atggtaaata agtcgtagta
     4141 atcttttgct ctcgaattat ctgtgccaaa gctgaacgta gcacttagct tttctgcaat
     4201 aatttgttct gttggataag ctggaatctc cactttttta tcttcaaaca ttaattggtg
     4261 atagtgtgta tctacttcag gataaataga atctcctgtt gtcacgtcca ttttaaacgg
     4321 tacacgtact ttctctaaat tagccaccaa tttaatttga aatccaggat aaaaatcggc
     4381 ttctcttgtt tccttcattc cttgaataga gaaaacaatg ccttcttttg tgggttttct
     4441 agttaaatca ttaaaaatgc tcttcaattt ttcttcagtt aatttgctat ttctaaatgt
     4501 cgtatcgata tcaattgttg tccttctatc gattccatat tttgatccta ataaaaagcc
     4561 gcctttcaaa atgaagtcat ttttgtactt tgattcagaa atttgttcaa ttagacgatc
     4621 catcataaaa tgccgttgca ctaactgtgc atttaatcct gtactctttg ctaaatttct
     4681 tgtttttgct gcaaattgtg tcggtgtcat ctttttcctc catcaatata agctttgcat
     4741 gtggtatttc atttcttttt ctacatgtag ttttgtcatg taatctctta atttacttgg
     4801 atctctcaat gggtcttcca tgtactcttt taatgcttct aatttcattt catattcaaa
     4861 ttcatatctc ggattccaaa tatcacaaag tgtacgctct ttatcataca tagtaatagg
     4921 atttccttga aaggaagttc cctctacttt tcctagttca taaacttctt tcttcacgaa
     4981 atgaaattgt aactgctgct cttttgtaat tgaacgatca acgttatagc catggggaaa
     5041 agttaagtga atgaatttcg gcatattcgt agaaagctgg taaatatcta aagtcgtttc
     5101 atgagagaag attcccctgg aaaatcgttg ctgaagccaa aataaatcat ctattccatg
     5161 accatcctct acataataac cacgatcaac tttgatcaat tttccttgat tcaccaatct
     5221 ttgtacagtg gttgctgcga ttccaaattt cctggcttcc ttcatagata aatttccatc
     5281 gcgaatagcc aacaattctt tcagtttatc ttgcatttac ttcccctccc ttcgttacaa
     5341 atacactaca tcaaatatat catagtagtt tatttgtaac aagattaacg tctatcgatc
     5401 taattcgatt tctttttgaa tgcgctgctg gttctttaat tgttgcagtc ttcttttatt
     5461 tgcacgtaat ttctcttgtt ctaaacgaat ttttgctttt tgattttcga tttcttgttg
     5521 tttgtgtgtt gtatttcgca taggataacc ccttcattat tttgtagtgc ggcgtgttct
     5581 tttcttatag ttcgtttttt tcttttcaga aaattcaaag cctgttgtaa agtcttcttt
     5641 taaaacgatc gttgcttcaa acgaaccttt ctgacctttt agtcctctga ctgattggct
     5701 tgttcggccg ttttgaatga tctctttcag ttgtgtggct gtgagtttct ttttggcaat
     5761 cgttgtccat aatttaaaat cacaggcttc agacgtacat gccgccacat tttgataaag
     5821 caagacttct tgttcccgac attttggaca aacacctaaa tgacgcgttg cttcctgttt
     5881 ttcactggct gctttcacct cttgtaacgt tgatccaaaa tctgttgact ggatttgtcc
     5941 cggtacgact tccaacaagt gagagacaaa tttttggata ttagctaaga aagtagcttg
     6001 tgttcctttc tgctcaccaa tctttaataa gtaactttcc catttggcgg tcatttcggc
     6061 acttgttagc agcggctctt tttccacggc ttggcaaagt aaaatccctt tatttgtcac
     6121 cacaagctta tttttttcta ccttgatata ttccttttgt ttcaaagttt caataatatt
     6181 tgctcgtgtt gcttctgtac cgattccttc tacttctttc aatatggatt gtgcttcttc
     6241 gctatccacg gtttttccag ctgttttcat cgctgtgatc aacgtacctt cggtataagg
     6301 ttgtggtggc ttcgtttctt tttcaaggac ttgtagatct accgtcaccg cttctccttt
     6361 tgtcacttta ggaagtagcg gttcttcttc cttttctttt ctgtcgctct ctttgccaaa
     6421 cagctttttc caacctagat ctactggtac ttttccgact gtctttagct gaagctgctg
     6481 aacttgcgtc aagatcgttg tttcttcata ggtatacttt tccgcaaaca tggccaccgt
     6541 tgtttttaac acttgttcat aaatagcctg ctgcagtgga cttaattgtt caaaagccgc
     6601 tgccgtcatg accgtctttg taggaatgat cgcgtaatgt tcctggactt tcttattatt
     6661 cacatatcga ctattcggtg tatgaatagg agtaggaatg gcttcggcct ttaaaaagtg
     6721 tttgtattcg tctaagtgat ccaacagata cgcatactcc ccttctgtaa tataaggggt
     6781 atctgttcgt gggtagctta gatatttccc ttcatacaac ccttgcatgg cttccaaagt
     6841 atctttggca ctagctttca tgagctgatt cattttagat tgaaggctgg atagagaaaa
     6901 aagacgtgga cttgccgcac tttttttctc ggtttcaact tggtggatcg tacctggctg
     6961 ttttcccaat tgaaccccct tttcttttaa ataatcttca aatgcttctt gcgtcgcttg
     7021 ggtttcattc ggatcaagct tcgcatcaaa tgcgccattt tgagcgatta cttgggcttt
     7081 tccttcaaaa tatggttctt tttggaagtt tctaatcttt tcctgtaatt gataaatcat
     7141 gtaaagcgtt ggggtttgga ctctgcctaa ggaaaaactt cctggtatgc ctttttgctg
     7201 caagagtaaa ctatacagcg ggctaccgtt catgccgatc aaccaatcgg cgatctggcg
     7261 tgcttgtgct tcttcaaatt ttgggtaggt ctcttctgca tctcgtaact gctggaatcc
     7321 ctgataaatg gcttcttttt ctaaggagtt gatccaaagt cttttaaata tctttccatg
     7381 atcggcgcct gcttgttgaa tgatcgtcca agctatcagt tccccttcac gatcgctatc
     7441 tgtcgcaata ataatggtgt cggccgattg aagttgctgt ttcaccacct tgaattgctt
     7501 tttcttatct ttaggaacat gatagtgata atgtgtaggg aaaataggca aatgctctaa
     7561 tgaccattgt ttccaatttt catcgtacat atcgggcgaa tctaactcga ctaaatgacc
     7621 aaaaccatac gtgatcacag tttctcctga aaacaatcga tcttggatct caaaataccc
     7681 atcttttcgg gtagctttag aaaagctatc ggcataagcc ttcgcttgtg acggtttttc
     7741 tgctaaaata acggttttca tcatgacgat ttcactccct ttcttgctgt ctaccttgtt
     7801 gaaacaacat ggcacgtttt tgctttctga tctcttgttg gtagatttca tgcttcaatt
     7861 gatcattcca atcctttttt acttcaggta caaattcatg ttcatgattt ttatagcctt
     7921 tgtagtattg ttctgcttta taagagaaaa gaatctgagc attaatatcc cctttttctt
     7981 gataaaaacg atcaaaatcg tacgtaccat ccacgcgttc acaagctttt aattcttttg
     8041 cgacttctct acaaatatct ttcaaattaa tagcttctat tgaatcgtta acagaaagct
     8101 gctgaccaaa agacgcattt actttgtgag cggaaaccaa ttggttcgtt aattgcagat
     8161 tgttttctgt cttgtgtatg gccataatag cttctggtgt gatcttttct tcttttgcga
     8221 cttcttcata aatgactttg tattcttttg gcacttgcca atcattagcg attcctcgtt
     8281 cacaacgtac tttctgattc gtaaatggat caactgcgcc cattaattgt tctttttcgt
     8341 agaaaatatg tcctgcacgg tcattatcca cacaaatctc gatggattga ggaaaggctt
     8401 gtttctttct caattcagat actgcctcac caaaataatg actgatcaca tggtgtttta
     8461 acccttccat cgaaactaac cacgtatcgt ttaactgatc acgatttagt gcagcatagc
     8521 taagtaaatc aatactactc tcaaaaaatt ttaactgctt agggtcaccg atctttaggt
     8581 taaagccatg attcgctgtc gaatttttat ctatatgctt atatgtgcct ctctcaccaa
     8641 aacgttcata atcaatgaac gttccttgat aactcgcccc tactgtctca tttgtctgtg
     8701 gatctttcca taaaaaggcg accgcatgat ctaaacgatc gtctcgaact aagaaatttt
     8761 gccgttcatg ttttggcttt agttcggcaa tcaacccttc tttttctgca taatcaatca
     8821 gccactctgg tagttttcgt tcttccttca gataattcct tcctttttct gtgagtggtt
     8881 gataatcaac ggggtgatct ttgtactttt ctgtctcaaa atgaagattt tccactcgtt
     8941 ctgttttgtc ttcattcttt agaataaaat cagtggctgc tttaaattgt tgcttagggt
     9001 cttggatctc tttgtctatg aaaaaaagtt tagctaattc aataatgtcg ccactaatat
     9061 tttgactgtt ccaataaaaa cgttgttttc ttcgatcaaa aacaaatgaa tcatggtctt
     9121 ctaagcgata gtctcgtcct ttattgacta cagccattcc attgtttcga gcaaaatcca
     9181 ctatatcgat ctgtttacat cgatcaataa gactcatttt tttctcggtc attttaaaac
     9241 ctcccaaaag aaaaaagact atccgttttt cagatagtct tttttacttg ttttatacac
     9301 gttctttttg tgacaattgt tgttcataat agatttcatt ttttcgtttt gccacttctg
     9361 acactgtctc aagtgaaaat cggaatgaat ttcctagcgc aaattcttct gaaggtaacg
     9421 ccgtttggat ctcttttcca taactttttc cttttaaaat tacttgatta tgctgtggat
     9481 cttcaataaa cgccgcatcc ttcaaatgta acgttcgacc cgtatcttct tccattactt
     9541 tcccgtcttt cttgtcgatc caaagtgaac caacaggaac aatattcttt tgttctgccg
     9601 tttctacagt atttttatgc tcctgcttca cttctgctgg ttggatctct ggttctcttt
     9661 ctctgtattg attgatttca ttagaaatgg tttgaatgaa ttcatttgcg acacggctga
     9721 catcattcat gattttccca cgttccgcag cttccttatc atccaacgtc tgaccattct
     9781 tcgtccatgc tgcaatataa ggaatagctt tctccgaagt gtccattcca aaatgtttgc
     9841 acacaatata agaagtcatt tctgcctgca attctttagt tgcggtatct aattctgaaa
     9901 atttgtgcat tcttgcatgg gctaattcat gaatacttgt agctaaatgc tgcgtaggag
     9961 tatttcgagt attcatgacg atttcttctt cgccagtaaa ttcgttacga acatatgccc
    10021 cccgtgcttg tcctaattct ctttgataga cttcactttc tgtcatatct cgaatttgta
    10081 ttccaatatt gttggctacc gcttgaatcc cagcttgaag ttctgactgt ccttttttat
    10141 ccaattgaaa atcaaagaca cggttcggaa agattttcgg atagtcttca ggttttaact
    10201 gtgtttgtgt gatatcaaac actttttcaa tcgtgtagta aggttttttg atcacttcga
    10261 tttgaccact ttcgattcgt tttttatctt ctggtgtagc ttctgtttct cgaacaaagc
    10321 cacgtccttt ctcataaaat cctttgaccg tttttctgac aaagatcttg ttcccttgtt
    10381 cccctttttt gatatagatt ccttcttttt tcaacgcagc acgacctaaa caagccgttg
    10441 cacctggaaa ttgttcctca atcaataatt gatttctaaa ggatcgttct ggaaaacgag
    10501 acataaaatt caaaagttct ttcacgtctt caggagaatg ggtatgcttt ttcaccgcat
    10561 ccagtgcctg ttgcgaaagg gatttgactt cttgcttaat ctcttctgcc gttcgttttt
    10621 gatagccctt ttgttttgtt tttgtttctt tcgactgcat ttgttctttc gaaacaggtt
    10681 catttttgac cgtttgtttt tgttcctttt caggtacttg ttcgcacaat tttgctaact
    10741 ctaaatagat gggttgatta ctgttgacgc catcccctag atccattcgg atctgatcga
    10801 ctacttctcc gttcttcact tcttcaaaat agaatttata ataacctgct tctgcggcgt
    10861 attggttatc caacgttttg agttgatcga tcaattctaa tgttacgatc tccccaccat
    10921 aacttttcaa tcctttttct ggatcatttt cgttgaattc tactcgatag aaatgatcgt
    10981 tttctttctc cttcaaagaa tcagttggcg cagcctcttc aagtaattca cgaacagctg
    11041 ctttttcctc ttccgacgtg gcttggtatt tttttgattc ctcaaatccc ccgttttcat
    11101 tcagttctaa agcaactttt cgatagtctt tcaaaaaata aatggttgga ttttttttcc
    11161 attgcgtcac tcgtccgctg tcaataattg cttgtacttc aggaagaaga ttttcttttc
    11221 ctttttctga tctttctttc agctgttcta atgtttccaa tttccgttgg tattttcgga
    11281 tcgtagcggc tgaaaaagtc gattcacctt tttcaaagcg ttcgatttct tctttgattc
    11341 ttggaatatt ttcgattgtc atatccaggc cgccgtactt gttatagccc atttccttta
    11401 gctcttcttg tctttcaagt ttttctacct gtttttcttg ttgcttgatc tcttctctca
    11461 gactatgcac tttgttttct aaacgttctt gttgcctaaa ccaagaatgc ccatttctct
    11521 tatcgttcat tggctgaccg ttggtctttc tctggtgttc aaacatcttc tcaatttgtt
    11581 cgtttaattc attttgcaat cgtactaatt ttcttttgga ttttcccaag cgactattgt
    11641 ctagtggttc tttttcttct gccatgtcc
//
LOCUS       DAFTHM010000081        11520 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFTHM010000081 DAFTHM010000000
VERSION     DAFTHM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.081"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(39..2114)
                     /locus_tag="L7C88_002123"
     CDS             complement(39..2114)
                     /locus_tag="L7C88_002123"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBP9558932.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2116..3033)
                     /gene="glyQ"
                     /locus_tag="L7C88_002124"
     CDS             complement(2116..3033)
                     /gene="glyQ"
                     /locus_tag="L7C88_002124"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBP9558933.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            complement(3417..4229)
                     /gene="recO"
                     /locus_tag="L7C88_002125"
     CDS             complement(3417..4229)
                     /gene="recO"
                     /locus_tag="L7C88_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBP9558934.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(4372..5271)
                     /gene="era"
                     /locus_tag="L7C88_002126"
     CDS             complement(4372..5271)
                     /gene="era"
                     /locus_tag="L7C88_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBP9558935.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5286..5681)
                     /locus_tag="L7C88_002127"
     CDS             complement(5286..5681)
                     /locus_tag="L7C88_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBP9558936.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5665..6141)
                     /gene="ybeY"
                     /locus_tag="L7C88_002128"
     CDS             complement(5665..6141)
                     /gene="ybeY"
                     /locus_tag="L7C88_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBP9558937.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6158..8350)
                     /locus_tag="L7C88_002129"
     CDS             complement(6158..8350)
                     /locus_tag="L7C88_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBP9558938.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8374..9345)
                     /locus_tag="L7C88_002130"
     CDS             complement(8374..9345)
                     /locus_tag="L7C88_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBP9558939.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10051..11430
                     /gene="brnQ"
                     /locus_tag="L7C88_002131"
     CDS             10051..11430
                     /gene="brnQ"
                     /locus_tag="L7C88_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBP9558940.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMPLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
BASE COUNT         3105 a         2441 c         2106 g         3868 t
ORIGIN      
        1 ttttgtgcct attctctggt ttatttacat attagaaatt attttgtgat gatttgatct
       61 aaacttgcta gcgacaaagc catggcagca atttgactta attgcgttaa tcggttctta
      121 cgtactgctg gttcttctgc catgaccatc gtctgatcaa aataattttc gatcagtggg
      181 cgaaggctta caagctgatc ataattttcg ttgatcgttt ggtcagcaaa gctttttttc
      241 attgcctcta ctgctttgtg cagttctttc tccgcttcat tttcgaacag ttcagggtct
      301 acttctgatt gtttttcaag ctccgctttt ttcgctaagt tcacgacacg tgtcaaagct
      361 tccatcgatg gtttgaagtc ttcatctgca agatgctgct tgaacaattg tgctgctgca
      421 aatacttttg tcagatcttt ttgttctgca ttcaaaacag cttcgatgac atcatgacga
      481 atattcttcg ttgtcaataa ttggcgcaga cggcctttga taaagtcgat cacctgttgt
      541 tgcccttctg ataaaccaat gccgaaacga tccgtatctt tactgataac atcactaatc
      601 gtttcttgca gaacagacaa aggaaaggcc cattttttcg attcgatgat ccgaacgaca
      661 ccgtatgctt ggcgacgtaa ggcataagga tcgtttgacc cgcttggaat catcccaact
      721 gcaaagaaag aaaaaatgct atctaattta tctgcaatcg ctaaaacaga acctactgta
      781 gactgaggta gctctccttc actggatata ggcatgtaat gctcacgaat cgctgttgct
      841 acagcaggtt tctcgccttt cagcagagca tatttttcgc ccatgatccc ttgtagttca
      901 ggaaattccc ctaccatgtt ggttactaga tcaaatttat agatttcagc agctcgttgc
      961 agatccatca attcttcctc agatagtcct acttgttcgc caatgatacg ggcaatgact
     1021 tgtacccgct gcattttctc atagatacta ccgatttttt catggaaagt aacagttttt
     1081 agtttttcaa cgtattggtc gattgaagct ttcttgtctt cattataaaa gaattccgca
     1141 tcttctaaac gagccgtcaa tactttttga ttgcctcgaa ccacattttc caattttacc
     1201 cgatcaccat tacgagcaga aataaaatga ggaagcagca taccttgatc gttccgtacc
     1261 tcgaaataac gttgatgttc tttcatagaa gtgactagta cttcttcagg aacagaaaga
     1321 tatttttctt cgaagtcgcc agaaaagaca gttggatatt cgactaaatt gttgacttct
     1381 tctagtaaat cttcgtctag atcaataacc cagtgatttt tttcggctaa ttcatttgct
     1441 tgtgtaacga tcatttcttg tcttttttgc ggtgaagcaa taacgaattg ttcattcaat
     1501 ttttcttcat attcttttgc atgcgcaaat gtcacatctt cgcctaagaa acgatgtcct
     1561 cgagaggctc tgcctgtttt gacatctaag atctcaaacg ggattacttc gtcatctaac
     1621 aatgccacga tccagtgaat agggcggata tattcaaaat cgtattctgc ccaatgcatc
     1681 gttactggga aagtgaggct tttaatgaca tctgctaaac ctgtcaatac ttctttcgct
     1741 tctttgccgt gagtgtattt cgttacatag acatattcca cgccttttaa ttctctaaaa
     1801 gtgatagcat ctgtcgtcag accttgtccg cggacaaatc cttcagctgc tttcgtccag
     1861 tttccatctg cgtccaaagc aatttttttg gctggtcctt tgacttcttc ttcactgtct
     1921 gcttgacgtt ctggaatgtt tgttactttg attgctaagc ggcgcggtgt agaaaacgtt
     1981 tcgatcgtat cataagtcaa ttggttttca tctaaaaatt ttgctgtttt ttcttctaat
     2041 tgtttcatgc ttggtgtgac aacatgagca ggcatttctt ccagcccgat ttcaagtaat
     2101 aagtcttttg ccatcttatt cagcctcctt catgttttct ggatttgctg tgtttttatt
     2161 caataaaggg aatcctaatt tttcgcgttc tgccacaaag attttggcta cagcacgagc
     2221 catgttgcgg atacgggaaa gataacctgc tcgttctgtt acggatactg caccgcgagc
     2281 atctaataaa ttgaatgtat ggctgcattt caaaatataa tcatacgctg gatgaacaag
     2341 attttcatcg atacagcgtt tagcttcttt ttcaaaacgg tcaaagttgc ttagtagcaa
     2401 gtcttggtca cttacttcaa aagaatattt ggaatgttca tattctggtt gtttgaagat
     2461 ctcgccatat ttcacaccat cagcccattc cagatcatag acactttcaa cttcttgaat
     2521 atatgaagca agacgttcta gtccataagt gatctcagaa gtaactggtt tacaaggtag
     2581 tcctccgact tgctggaagt acgtgaattg tgtgatctcc atcccatcaa gccatacttc
     2641 ccaacccaca ccggcacacc ccatcgatgg gttctcccag ttgtcttcaa caaaacgaat
     2701 atcgtgttct aatggatcaa ttcctaaaag acgcaagctt tctaaataaa gctcttggat
     2761 attttcaggt gaaggtttca ttacgacttg aaattgatga tgctgataca aacggtttgg
     2821 gttttctcca taacgcccgt cagctggtcg gcgggatggc tctacataag cagcattcca
     2881 tggttccggt ccgattgccc gtaagaatgt atatgggctc atcgtacctg ctcctttttc
     2941 tgtgtcataa gcttgcatca gcatgcagcc gtttgatgac caaaattttt gtaatgttaa
     3001 aatcatatct tggacggtca attttttact catctgtttt gcccctttca atttttaagc
     3061 gttgctgtca ataagaatac aggaaagaaa acgacaaaaa gtccctatgt ctgattacag
     3121 acatagggac gaataatttc gcggttccac cctacttccg aataaagatt cggcagcttc
     3181 atttatcgta ctcgcaagtg cctcttcaaa aatcgtttgg gtccggcttc cactctcccg
     3241 aactcgctaa accacgtgtt ttttactgat cttggtcaat gtacgtattc attttgcagt
     3301 tttcttgttt atataataga tcctctcagt gaacgatcta tttaatctac ggttaataat
     3361 agacggaagt ccctgtattt gtcaaatagt tttgattttt ttgttgtatc tttcatttat
     3421 tcttcttttt caggtatctc tttttcaggc atatttttct ctggcgtctt taatacgtgt
     3481 gcccaagact tcatttgatc aatgaacttt ttgcttttta gatgaatacc gacatattca
     3541 tcatacaact ggtcaatgag gtcacggatt gcctgcttcg tttcttcttt caagtggatt
     3601 ccactgatct tatcataaga aatagccgaa aacattcgaa cgaaataaac agcgcgagga
     3661 tctgcatgat aacggtgttc gtccattggc cagtgtttct cgcatatcac accgccagat
     3721 ttggaagaat agtcaaattt tccttttgtt tccccgcata cgacacagtg cgtccaaatt
     3781 ggcgcgattc cgaagcgttg cagtatttga acttcaaaga tattcgtgat gatttctgca
     3841 tcatctcctt gatccatccg ctgcagagct tgttgcgtaa attggaataa atgcgggtca
     3901 tattgatgat cttcgattgc tgcatctact agatttagca aataggtacc ataaccgctc
     3961 aaaaagatat cttcttggat gttccgaaac gcatggacgt ctttgacact gcttaaaaac
     4021 gacaaacctt cacttcgaaa attaccgata tagactgctt cggtaaaggg gagcaaagcc
     4081 ggagctaatg gctgattttg ccgatggatt cctttgatat aaaacatcat tttgccagaa
     4141 gattccgtaa agattttgac taatttatct ttttctttgt aattacggct agataaaatc
     4201 aagcctttcg attctgcaag ctggctcata ttctccctcc taaaaaataa atctggaaaa
     4261 gcagattctg ccgatccaga ttatttatgt ttcgatcttc cgccgttttt ctcaacgtgc
     4321 ggatttttat ccagtttatt tctatactta acctataaga agttcagaat atcagtattc
     4381 gtcttttcgg tagccaaagt cttgcagata gacttttttg tctcgccagt ctttttggac
     4441 tttgacccaa agttctagaa atactttgtc tcctaaaaga ttttcgatat cctttcttgc
     4501 tttcgttcct acttgcttca gcatttttcc gcctttgccg ataatgattc ctttttggct
     4561 atctctttcg acgatgatcg tggcctggat atggatttta tcattctcgt ttcgcttcat
     4621 cgaatcaaca acgactgcga cagaatgagg cacttcgtct cgtgttaaaa acaagacttt
     4681 ctcacggatc aattcagaaa cgataaagta ttcaggatga tcagtcactt gatcatctgg
     4741 aaaatattgt gggccctctg gcatttcact gactaataca tccattaagc gttcgacatt
     4801 gtttccttct gtagcagaga tcggaatcac ttgtgcaaaa ggcatctgcg tcgaataatc
     4861 ttcgatgatt cccagcaact cgtctggatg gatcttatcg attttattga taatcagata
     4921 aactggagaa tgcacgtttt ttagacgttc aataataaaa tcgtctcccc ggccgcgttt
     4981 ttgatcagca ctgatcataa ataagactgc atccacttct ttcaacgcac tgtaagctgc
     5041 ttctaccata aaatctccta gacgatgctt tggtttatgg attcctggtg tatcgataaa
     5101 aatcagctga gcttctggtg tagtatatac tccttggatt ttatttctag ttgtctgtgc
     5161 cttgtcactc ataatggcaa ttttttgacc cacgattcgg ttcaataatg tggattttcc
     5221 tacattcggg cggccgacga ttgcgacaaa ccctgattta tgttctggca tatacgttct
     5281 cctttttaat taaacaacaa atgatatatt ttagggacaa ataaaatcaa cccaatgatg
     5341 acagcaaaac aagcggtcac taaaactgct ccagctgcca tatctttgat ttttttccca
     5401 atcggatgaa aatgaaaatc cgtaaacatg tccactacat tttcaaaaac agtattgatg
     5461 atctctacta tccaaacgag aaaaacagct aaaagcagcc ataaccactc tatccgatca
     5521 agctggaaaa tcacgcccat aaataaagca aggataccga acgcaacatg tttcctcata
     5581 ttgcgttctt cctcaaaaac ggttttgact ccttggacag caaattccac agacatcagg
     5641 aaatgtttgt ttttctctac gtttttatct tttgagtcca taggcatcca agatctcttt
     5701 ctgtaaacca aacatttctt tctcatcttc tggtgtcata tggtcatacc cgttgatatg
     5761 caagaatcca tgtaccgcta aaaagccaag ttcccgatca tatgaatggc cgtaagcttc
     5821 tgcttgttca gcagcacgtt caatagaaat catgatgtct cctagtacac gaggcaatgg
     5881 attctctcca tcttcaaaaa tcactgggat ttcgtcttcg ccttcttctt ccagagcaaa
     5941 actgatgacg tctgtcggtg catcttttcc acggtaatca cgattgatta cttggattgc
     6001 cgcattgtcc atgaaagtaa cagacatttc tgtttcctct ggcagcttta aataagatgc
     6061 tgcaaattgc agcaagtcat cgatttcttt cattttctct tctgagactt ggtttgtttc
     6121 atccataaag gtaatatcca ttatacatcg cttctttcta ttcttcttgt tcttccttta
     6181 tcttctcaac ttctgttttc attttaggat atttgatccg agaatggaag gtgctactta
     6241 aaccgctgat caatgatttt tccacttttc ggatttcttt caaggtcagt ccactatcgt
     6301 ctaattgacc atcggaaata cgctcttcga taagattatg gacaaaactt tcgatttttt
     6361 cgctcgtcgg atgatccatt gcccgtactg cagcctcaca actgtcagca atattgacga
     6421 tccctgcttc acgactttgc ggttttggtc caggataacg gaattgctct tctgttactt
     6481 ccggattgcg ttctttcgct ttgatgtaga aataacgcat tagcgtggtt ccatgatgct
     6541 gtttgcaaat atcgatcacc atttgcggca tattataatc ttccaatatt ttggctccat
     6601 ctgtcacatg tccaaagata atatgtttac tgtcttctgg caataagaaa ttgtgcgggt
     6661 tttccgctcc tgaaggcaag ttctcaacga aaaagctagc atgtttgatc ttgccgatat
     6721 catgataata gcaagctact cgagttagca aagaacgtcc gccgatttct gctacagcgt
     6781 tagcacttag attagctacc atcatactat gatgataagt acctggcgct tcttccagca
     6841 actgtttcaa taaaggatga tttggattgc tgagttcatt taatacaatt acactgtcat
     6901 cattgaccat caattcaata tatgggtgta gaccgatcgt cagcaagaat gagaagagtg
     6961 caccagtgaa cccgcagaca agcattaacc aagtcgttgc atcaccaaag ctcattcctt
     7021 gatagacgat caaaatgaca tccatcatca caggaaaaat aatgacccac atggcagcag
     7081 ataatccttg ttctgagatc cgtttgcgtc tgacaatcgt tgccatgagc ccagagaaaa
     7141 cataagacat caagataatc gttagaaagt tcgtgccaat cgaatcataa aaaatgaaaa
     7201 gtgcagatac tgcttggaaa ataccagcca tgatccctgc tcttcggttc aagaaaaagc
     7261 ttaaaacaag tggtgcaaaa gcagcgggat aaaacagcgg gatataagta gcttgttccg
     7321 tttggaataa ttggaaaaat ttcatcagca ctatgctgac tgacatagct gtcacataga
     7381 aaagcacgta ttttgttctt tctcctgcat tttggaattg aagtgaatta taaatcagta
     7441 cgccgatttg aagcaaaaca gctaaaacca tggcaattag cggaaaaatc gaagttgttt
     7501 gattagtcag tcctagtaat tccaattttt tcatagctga agcatcgatt tgattacctt
     7561 cacgaacaat gatttctcct tggaagatca tcactggttg tacagcttct cgtgcggatt
     7621 gtttcaattc ttctgtcttt ttctcattca atacgtcatt cactacgata ccttgatcca
     7681 ctaagtagcg aatcatttgt tgttgtgctg gtgtgacatt caaatattgg atttgctctt
     7741 ctgcttcttg tttaaaagct tccaattcac tttcacgaac ttgtttgctc atctgttcgt
     7801 caatgagctt cagactctca tccctcacag tatggatctc agtttcagtc atttcaaata
     7861 tcgtcgaata aaaattgttc ggtagttttt gataaaacgc aacattttct gcattcacat
     7921 tttcaaaatt tttcttcaac gcggcgatcc gctcttctgt agtaggcttt gggatatttt
     7981 catcttcctt tgccttatca atcttttcgt cataagattt gttgatggca tcattcgttt
     8041 tatcgatcaa ttcaaatagt tgcttgatcc gattgttctg gtcatctgca agatcttttt
     8101 ggtaagtgta ttctggagtg actgcttctg ctgccagttt tcttttttgt tcggtttctt
     8161 ccgtgttctc gatcgttttg ttcgcacgga tactttcttc tgctacttgg ccttctctga
     8221 aatcattggc cttttgtttg acactactaa atgtaacgcc gcagataatg ataaaaaaca
     8281 agaacagcag gaaaggcaat gctgcctttc caagtttttc ttgtagtttc tgcagtgttt
     8341 tattcaacat gtgcttatcc tcctaagcaa agcttattct tgatggagat ctgccttttc
     8401 ataagctttg atgatttcgg caactacagg gtgccgaaca acgtcacttg cttcaaaatt
     8461 aacaaaatcg attttcttga tttgctttaa tgttcgttct gcatgaacaa gaccacttgt
     8521 tgtccctcga ggcagatcaa tctgactcgt atctccattg acaatcattt ttgattgata
     8581 accaagacgt gtcaggaaca ttttcatctg agcaactgtc gtgttctgtg cttcatccaa
     8641 aataacgaat gcatcatcca atgtccgccc ccgcatgtaa gctaaaggag caatttcgat
     8701 cacgcctcgt tccatcaatc ggttcgtatg atctaatcca aaaatttggt ataaagcatc
     8761 ataaacagga cgcagataag gatctacttt ttcttttaga tccccgggaa gaaagcctag
     8821 attttcccct gcttccacag caggccgcgt caaaatgatt ttttgcactt cacctttttt
     8881 caaggcagcg attgctaata ctactgcaag aaaagttttt cctgtcccgg ctggtcctac
     8941 gccaaatacg atatcatgtt tggctaccga ttcgacatat ttcttttggc cgctgttttt
     9001 tacccgtatt ggttttccat tacggtcttt gacgatctct tcctcataca tttcaacaaa
     9061 ataatctaat gtgccttttt gccccatttt cagtgccgtc acgacatctg gtgtacttac
     9121 atggattcct cgtttgatca attcctgcaa tgtccgaatg actgaggcag ccaaggaaat
     9181 ctgggattgt tcgccaatga tctgaatgat ttctccacgt gtatggatgg ttgtttctgt
     9241 tgtttcttca atcagtttta tatgcttgtc gtgtgcacct aaaagcatgc tgacatcatc
     9301 agcagccgtc aatctaatct ctaaagaact agactcttcc gtcaaaaata gacatcccct
     9361 ttttttcgat tcattctttc ctattttacc atactcagaa gaaactatat agcaaataag
     9421 aaaaggttct aaaagagttg cttaaccata agtaccaaga aacgttaaaa aatagctgct
     9481 tccattctct aaaggtctcg tttgaataaa aaaagctgat catgtaagct atgcataaga
     9541 tagaggacaa gtattccgtc taacttagca agtattctct gggtattttt cttgtttcaa
     9601 aaaaagaaaa caaaatattt gaaatattct tgcatttcaa aaaaaacagg tgtattataa
     9661 cgtcaacaaa taaatataca gcaaagcgtc gaggaaaaca gtaggctatt cagcgattta
     9721 ttcccagtga gtcatgtaag tgagaaatga caataaatcg aatagacgaa catcatttcc
     9781 gagtcaatgt cgaaaacgta gatcattgtg gctgcctcca ttatcaggct agcggataac
     9841 tttatcgaaa agcgtccgtg aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt
     9901 ctagaatcta gagccctttt cccaagtgga aaagggcttt tttttatatt ttaaggtggt
     9961 ggttttcatg gaatctgata ttagtggcat ttctagtttc tgcaacgttt attttgttac
    10021 tcaaaatgat aattattgga ggaaaaattt atggaagaaa caaaaactta ttcatggaag
    10081 caattattga tggtcagttc acttatcttc gggatgttct tcgggtcagg taatctgatc
    10141 tttcctgtcc acttaggtca aatggctgga tcaaactgga tcagcgctgg tgtaggattt
    10201 gccatctcag gcgctctttt cccattatta gctatcttag ctgtagtagt gacaaaaagt
    10261 gatggtctgt atgacttagc taaacctgtc ggaaaatggt atgctgcctt gttcttgatc
    10321 cttgttcatt taacgatcgg accattcttt ggtacaccgc ggacagcagc aactgctttt
    10381 gaaatggctg ctaaaccctt tttgcctgaa aaatatgatt cattaggtat gtttttattc
    10441 tctgctcttt tctttttact tgcttatttc cttactgtac atccaacacg tttggtcaaa
    10501 tatgtcggaa agtatttaaa ctccttgttt cttgcattat tagctatcat ttttgtcgtt
    10561 tctttattcc aacccatggg gaatctaaac caatctgctg cagattctta tcagacgaac
    10621 gctttgacaa atggcgtttt agaaggatac aacacggttg atgcagtagc tttacttgct
    10681 ttaagtgtca cttttgtcca tgcagttcgt gatcttggtt ttaaagataa aaaagtcaca
    10741 gaattaacag caaaagctgg tagcctgagc gttgcgttag aagtcatgat ttattttggt
    10801 ctggtccttc tcggtgcgat gagtttgaat aagatgcctt tatcagaaaa tggcggaact
    10861 gcactttctc agatcactaa tttttattta ggtaacttcg gtgctagctt cttaggggta
    10921 atggtcacat taggtgtctt cactaccgct atgggactcg ttgtttcttt tgcacaagat
    10981 ttccataaac tgttccctaa agtcagttat atgacatggc tgcggttaac gacttttgtc
    11041 tcttttgtcg ttgcgaatgc cggattggat aatatcatcc aatggtcttt accagtattg
    11101 atgcttttgt atccattgtc acttgcgtta atcttgcttt ccttaacagc aaaattcttc
    11161 caaaagagtc catttgtcta tcaagtaacg atgttctttt ctgccgttcc agccgtattg
    11221 gatatgttgg caaattcgcc tgcattagtg agtcagcaaa ctgtcgtagc aagcttacta
    11281 ggattttatc atcatcacgt tccttttgct gcattaggac ttggctggat ggtcccaacg
    11341 ttacttggtt acgctggcag cttactcttt tattacgcct atcgcctatc agggtataaa
    11401 caagaagcaa atgaactacc agaagaataa ccaaatcaaa cacaatttaa cataagagat
    11461 attaaacagg aaaaaaacag ctagaagaaa gaatcttatt ctttcttcta gctgtttttt
//
LOCUS       DAFTHM010000082        11504 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFTHM010000082 DAFTHM010000000
VERSION     DAFTHM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.082"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(106..651)
                     /locus_tag="L7C88_002132"
     CDS             complement(106..651)
                     /locus_tag="L7C88_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBP9558941.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(663..1355)
                     /locus_tag="L7C88_002133"
     CDS             complement(663..1355)
                     /locus_tag="L7C88_002133"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBP9558942.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYKPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1374..1658)
                     /locus_tag="L7C88_002134"
     CDS             complement(1374..1658)
                     /locus_tag="L7C88_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558943.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1671..2234)
                     /locus_tag="L7C88_002135"
     CDS             complement(1671..2234)
                     /locus_tag="L7C88_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBP9558944.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2462..3124
                     /locus_tag="L7C88_002136"
     CDS             2462..3124
                     /locus_tag="L7C88_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBP9558945.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3248..4444
                     /locus_tag="L7C88_002137"
     CDS             3248..4444
                     /locus_tag="L7C88_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBP9558946.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4545..5921)
                     /locus_tag="L7C88_002138"
     CDS             complement(4545..5921)
                     /locus_tag="L7C88_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9558947.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5958..6824)
                     /locus_tag="L7C88_002139"
     CDS             complement(5958..6824)
                     /locus_tag="L7C88_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBP9558948.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6913..7938)
                     /locus_tag="L7C88_002140"
     CDS             complement(6913..7938)
                     /locus_tag="L7C88_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBP9558949.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7956..8630)
                     /locus_tag="L7C88_002141"
     CDS             complement(7956..8630)
                     /locus_tag="L7C88_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9558950.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8814..9707)
                     /locus_tag="L7C88_002142"
     CDS             complement(8814..9707)
                     /locus_tag="L7C88_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBP9558951.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9781..11478)
                     /locus_tag="L7C88_002143"
     CDS             complement(9781..11478)
                     /locus_tag="L7C88_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBP9558952.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
BASE COUNT         3411 a         2522 c         1971 g         3600 t
ORIGIN      
        1 tttttttaaa ataacgtata aaaaagagca taaaacaaag tcgtttgttt tatgctcttc
       61 ttttattatt ttgtgctttt tattttatca aatcactttg tttttttata aaatttctgc
      121 gcctagtgtg gactcaaaat gtctcaatgc ccattcatgt ccaacgggat cgaaacttgc
      181 cacggcatct ttgaaaatat ggagtttgta tcctagatta tacgcatcga ctgctgtatg
      241 caacacacag atatctgtac atacgccggt caaataaata tctgtgatct ggcgttctcg
      301 caaacggatg tctagatctg ttccactaaa agcggaataa tgccgtttgt ctatccaata
      361 aacattttcc tcttgctcat agtcttggta taaacttttt aaagagccgt acaattcccg
      421 tccacccgtt cctatcacat tatgcggagg aaataagcgg ttctccggat gaaaggaatc
      481 ttttggatca tgcgcatcaa tggcaaaaac gacaaaatcc ttttgatcaa taaacttctt
      541 tgtatgagca gtcagctttt tttcaattac ttgtcctgct gtcccagtag tcagctttcc
      601 atcctctgca acaaaatcat atgtgtagtc aatcgagatc aatgcgttca tcttagtcct
      661 ccttatacga gatgtttgac aaattcgatc accatttctg ctgatcgttt gcctgcgtct
      721 tcgataaatt cgtcaaagct ttgtgtcgcc gagtgatctg ctgtgtcgct cattgcacgt
      781 acgatcaaaa atgggatatt gaactgacga gctgtttgtc caacagcggc tccttccatt
      841 tcgcaagcta atgcttcagg gaaattcgtt aagatttctt tgattttatc tggcgagtcg
      901 acaaatgtat cacctgtaac gatcaatcct tcttttgcgt tcaaattcgt tgcttttgct
      961 gctttaacca tttcactgcg caaatatgtg cttgcttcat aatatagagg cattcctggt
     1021 aattgtcctg gtttgtagcc aaatcctgtt gcatctgcat caaaataagc tactttgtct
     1081 gatataacga tgtcacctac ttgtaagcct tcaccgattc cgccagctga acctgtattg
     1141 atcaccatgt tcacgccgta ttgttggatc aacagacttg tggtaataga tgctaagact
     1201 tttcctatac cggaacgtac gacgatcact tcgtggttac ctaatgaacc tgaaataaat
     1261 aaagcgcctg cgcgttccca tgataatggt tcgcttaggt tctctctcaa aatttttact
     1321 tcttcttcca ttgcgccgat aataccgatt ttcatctttt taattccttc tttctatata
     1381 aatgcgattg ctaaaaaaac cacacataac attaggataa caataataag agatttcatc
     1441 aaaaaagagt tccatttggt cgtcttttcc cgttcgctga tccttgtttt cgtgattggt
     1501 ttattctttt tgctttcttt acgataaaag ctggcaatct ttttttcttc ttgctgataa
     1561 gctgtttctg cttttcgctg tttttttaat gactcgcttg cttgtgcttg ttgtcgcttg
     1621 cgaagttcgc ttcgcgtaat aagcggtcct ttggccataa gccgatccct ctactttcct
     1681 ttggtcaata gttcccagta ttgaatcgca taaatcgtct ttgcatcaca aatcaactga
     1741 tctttcatcg cttgttgcgc ctcttcaaga gttagatgat acaactccag tacttcgtct
     1801 tcatcttgtg ctaaaggatt ctcgaccttc tctacccctt gtgcatgata aatatgaagg
     1861 acttcatttg caaaacctgg tgaaagatac atcgaagtaa gatggctcag cgacttcgca
     1921 cgatagccag tttcttcttc taattctcta gctgctgtca tttcgggatt ttgtccttct
     1981 cctggatcga tttttccagc tggaatctcc aaaatcactt tttctaaagg ttttcgaaat
     2041 tgtttgacaa gaagcagacg atcttgttcg tcaaaagcaa tgatcccgac accaccagga
     2101 tgaaatacca gttctctctt cgaagttcct ccatctggca aacgaacttc gtctacagca
     2161 acatcaataa tttttccgct atagatttct ttgcgactga ttgttttttc ttcaaattgc
     2221 tcattgttca gcatatcttc tcctgctttc tttgtaatca taactgcttt tttttcattt
     2281 ttcaattttt ctcaaaaact ccttattagt ttaccataga taaaccttag attttctcta
     2341 aatatagaaa atccttcttt agtccgatac tctttctagt agtccgtatg ctaaaataag
     2401 tatgtaatcg aataacgaaa agaattcaat actcaacgat aaatgacatg gagggtttat
     2461 tatgataaaa cgaaattggc cgtggcttct agcattggtc ttgctatttc tctttgtccg
     2521 aaacaatagt ttttcttttg ttctaggact tttattgata ggtgtagttt tagttttgtg
     2581 gggactcttt ggttcgcgca ggaaaaaggg aaaacaagaa gaaattcctg cactgactga
     2641 cgaacttgaa actcactatg aaaaaagcgg tatgacagcg aatgaaattt cattttttcg
     2701 acaaacaatg aatcaaacaa aaaatgagat caatcaattg caaatgaata tgcagcagac
     2761 agccaaactt aaagcaatcg atctccgcca tgatccagtc aaagcagcga aagctttatt
     2821 caaagaattg gtgaaagaac caaaccgact gcatgaagca agtcagtttc tttatacgca
     2881 tctgccgaat ctagttgatt tgacaaataa gtataatgag atcaatgacc atgagatcaa
     2941 aaacaaacag acctatgaaa aactagaaga aagcgcgcag atcatcgacc agctgtcagc
     3001 tttaatcgca caagattatc aaaaattcgt tgctgaggat ctagatgata tcgacgtaga
     3061 gatatctgtt gcgaaacaga gcttaaagcg tgataataaa tatgaaccag aacaaaagga
     3121 ttaactcttt tgttcataaa agaagactcg gaacattcag atgatgtctg gctgtttcga
     3181 gtactttttc taaagtagag acattcatgt aagaatcgag aacagattca acaaggagga
     3241 attttttatg gatcataaac cgactgaaac aaaagatgtt acaccagtta acgatacact
     3301 tgaagattta ttgaacaacc cgttttcaac tccaacagat acgctgacca cttcacaaca
     3361 agcggagatt gatcagctcc aagagcaaca gacagctgct cgtttaattg acaaactacc
     3421 ggcggaacgc caagaacaag ctaaacagct agcagcaaaa atcgatgcta atgatgcaca
     3481 gtctgtcatc agctacggat cggctgccca agcaaaatta agtgaattct cacaatcgat
     3541 gttgaatcat gtgcaagcac aagatattgg tcctgtagga gattccttaa ctgaactgat
     3601 gtatcgtctc caagaagcca atcctgacga actgcgtgcc ggagaaggga acatcttcca
     3661 gcgtgtcttc gggaaggtca aacaatcgat ctatgaagtg acagcaaaat atcaaaagat
     3721 tggtgcacaa attgacaaga tttcagtgaa attagataaa gaaaaagacg gtctgctaaa
     3781 agataatctg atgttagaac agctttacca gaaaaacaaa gactactttg atgcactgaa
     3841 tatttatatc gctgctggag aattgaaaat ggaagaactt caaacaacga tcattccaga
     3901 agcgatgaaa agagcagaag aaactggcga tcagatggat gttcagattg ccaatgatta
     3961 cacgcaattc ctagatcgtc tggataaacg tacgcatgat cttcgcttag ctagacagat
     4021 cacgatccag caagcaccac aaatccgttt gatccaaaac acaaatcagg ccttggctga
     4081 aaagatccaa gcatctatcg ctacagccat tccgctgtgg aaaaaccaag tcgtgatcgc
     4141 attgaccttg cttcgtcaaa aagatgcagt aactgctcaa cgccaagtct ctgaaacaac
     4201 aaacgactta ttgaagaaaa attcagaaat gctgaaaatc tcagccatcg aaacagcgaa
     4261 agaaaatgaa cgtggaatcg tggatatcga gacccttcaa accactcaaa atgatttgat
     4321 cgaaacaatc caagagacat tgcgtatcca aaaagaagga aaagaaaaac gtcgtcatgc
     4381 agaagtagag cttggacaca tggaagaaga tctgaaacaa aaactgttgg atttaaccca
     4441 atagatcacc tttcgcttgt tactaaaaca aacgcccaac aacagtttat tacaactgtt
     4501 gatgggcgtt tttcttatct ttcttctaac ttctccattg gagtctattt ctcattcatc
     4561 ttgctgtgtc catagccata gccaaaataa atgatcagtc caataaccat tacgataccg
     4621 aacacgatcc atgtcacagt ttgcagacga agcatcaata caatacaagt caagatggag
     4681 acgattggca atagcggaac gaatggcact ttgaattctc cagcttttgg tttgccaaac
     4741 atttttctca acttcagtaa gcctagacta acaagcatca aataggcgag cgccatgata
     4801 ttcgttagtt ccgctaatac attcaatggg aaaaatccgg caaagaatac agctgccaca
     4861 ccagcggcat aagtcgcttt tttcggtgta cgatgctttt gatcgatttc tgtcataaac
     4921 ttaggaagta agccatcctt gctgacagca aacagtaaac gagcaagtga atacatcatc
     4981 gagatcgtta ccgtcagtag cgttaaaatt gcccctacag cgatcaccgc gcccactgtt
     5041 ccatgtccta catacctcat tgcaaaagcc actgggtcat tgactcctag ttcagtatac
     5101 ggaacgattc ctgtcaagat cagcgtcacg atgatgtaaa ggacagtagc aatcagtatc
     5161 gaaccaatga ttcctcttgg cacatctttt tgcgggtttt tgacttcctc ggctgccatt
     5221 gcaacggcat caaatcccaa gaaagcaaaa aacacaagag ctgcaccatc tagcacaccg
     5281 gaaaaaccaa aaggcatgaa tggctgccag ttatcaggtt taacgaaaaa tattcctaca
     5341 atgataaaca acgcgatgat accaaatttg acatatacca tggcattatt caaacgtaat
     5401 gctttcttgg cttcaagcga cacgatgtaa gtgacgaata tcactacgag caccgcaatc
     5461 aagtcaatgt atgtaccatt ttccggattg tacccgccag ttaatgcttg tggaagttcg
     5521 gcccctaaac ttttcaaaaa accttgcata tagccagacc atccggaagc aacagaggaa
     5581 accgctagta aaaattcccc gatcaacaac caccctgtca gccaggcagc aaattcacca
     5641 aatacaacat acagataggc atatggccca ccaatcactg gcactcgcga agcaaattct
     5701 gcgaaactta gtccagacaa aatgacaacg attgcagcta agacaaatga aagtgacagt
     5761 gctggaccag cattttgatt ggccgcaacc cctgtcacca caaatattcc cgtaccgatg
     5821 atcgcaccaa ttccaagcat gatcaaatca gacgttttta gttctttttt catctcactc
     5881 gtatgattga gattgatctc tttcttacga aacaaatcca ttgaagttcc tccccatttt
     5941 aggttggaaa acagcgatta aactgttttc atatacccta aaaggatacc acctaaaatg
     6001 actaaaaggc aaccaacaat aacataaatg agctcttttt tcgtttttct ttcgccaagg
     6061 atgaaaatcc cacctaaagt agagataatg atccccattt gtgaaagtga gaagccaaca
     6121 gctaaaccaa gtgatttgac tgttagaagc atgcagatgt ttcctaagcc ccataataat
     6181 ccacagatca tgtttttcca cacaaactga tcgactttaa ctttacggaa agcaaagaag
     6241 cttgcgccta agatcattcc gatactttga ggtaagataa ttgacatcgc atccaaattc
     6301 gcccagttga cgatgatggt atatacacca taaccaatcg tagagaagat caatgctcta
     6361 aaacccttac caaaatcaag cattttatta tctgtatcta tttttccttc gtcatcttgt
     6421 cgggcagtca aatacgcacc gcttacaaga agagctaaag caataatacc gtatacataa
     6481 tctttcgttt gtgtccattc atggaagaaa acggctcccg caatcgtatt caaaattaat
     6541 tgaaaaccag tagacaatgg tagccctaca gaaacaccca tgtacttcat tccatggaac
     6601 tgtccatttt gtccaacact ccaagctaag ccggataaaa atccgatcaa gaaaatccaa
     6661 ggggtgatta caggactaac aacgaaaaag acaactaaag aaaacagaaa tgcaccgatc
     6721 gtcattccta gtgtttgttg attggcatcg ccaccaattt taccacttac taaaccaata
     6781 ctaccccatg ccaacatagg gactaatgct attaaaattt ccataaccaa tctcctttta
     6841 tttcacatga taagaaactt atcagcgaaa acgttaacaa cacaagcact ttttttcgtt
     6901 tctaacgatt ttctaacgtt tttcattata aaaatttaag attgggaaaa ataaagtcat
     6961 tgttgtccct tttccttcag ttgattcagc cgtcaaatgg atacctaatt tttcggccag
     7021 attttttgct aaataaagtc ctaatcctgt tgaatgtgtt ttgctaagtc gaccatttct
     7081 cccagtaaat cccttatcaa agatccgttt caagtcttcc gctgggatac cgatccctga
     7141 atctttaact gaaaggctga ctccttgcgc ttccttttct atgctcacaa tgatgtttcc
     7201 gtgatccggc gtatatttga tggcattact aagcaattgg ttgaagataa aagcgatcca
     7261 tttagcatcg gtcaaaacag tatgatcctc accaacgatc tcgtagcgaa tatttttttg
     7321 gataaaataa tttgcctgac tgcgtatcac aggctgaatg attcctttta gtccatattc
     7381 ttggatgagg tagtcccgcg agaaactgtc gagtcttgca taatacaaaa cttgttctac
     7441 gtattcatcg atttttgata attcattttc tagtaatgta tacttttgat cgtcaatatc
     7501 gaactcgatc gaacgaacta gcaatttaga agcggaaagt ggcactttga tttcatggac
     7561 ccatgagtca atataatctt tttggtcttg ttgattactg attgctgatt gcattacttc
     7621 ttggtgttca cggatcagct gattgatata ttcttctacc agtttttctt cttctgtcct
     7681 cccaccactc aaataatttt gcaaagggga agttttttgt atgtcggcta attttcccca
     7741 ccatcttctc ttgctcaagt aaccacccag cagataaaaa atcagaaaga cgccctcaat
     7801 caaagctaaa taagcaattg tgctcaaatc aactttgatg tttggcgcca gccacatcac
     7861 aaagatcgtc aatgcaataa aaaacagcca tcccaagatc aatgtccact gatctttcaa
     7921 atatttaaaa aaattcatct taaccgctca tcctttcagg gaacgatata tccctgtcct
     7981 acttttgttt cgatatatcc ttggatacct gcctgttcga tttttcggcg taaccgattg
     8041 atgttgactg tcaatgtatt gtcatctaca aatcgttcgt catcccacag tgctcgcagc
     8101 aatttttccc gacttaagat ctttccattg tgcttcatca aaataaataa tagacgatat
     8161 tcatttttgc tcaaatcaat gatctctccg ttgatttcca tacttccgtt gtcaacattc
     8221 aacgtaatgc cattgtggct catcatttca ctagataatt ctgtgtagtt gtaagaacgg
     8281 cgaagtaatg cattgatttt tgcaatcagt acatcgattt ggaaatgttt tgtcacaaaa
     8341 tcatctgccc ccatgttcat agccatgatc atatccatat tcgtattcct gctggagata
     8401 aaaatgatcg gtactttcga tacttcacgt attttttgac accaataata gccatccaaa
     8461 acgggaagat taatatctag taatacaagc tgtggttctt ctctttcaaa gtctgagaac
     8521 acttgattga aatcggtcgt tccaaaggtt tcaaattgcc atttctcaag ttcctccatg
     8581 atcaattgtc gaatgatctc ttcgtcttcg actaccatga tttttgccat aaaaaatccc
     8641 tccatctttc ttcttgctac tacaatatca aagaagccct tgtgaaacaa gttggcttac
     8701 ctggaaaatg tcattttagc aaacgttaaa aaaaactgga aatatgcgat ttaatcgcgt
     8761 ttgtctcttc caagcagctt aaatttatta tgttattctt aataattggt ctattatctg
     8821 ttatttttct ttcgttgttt ttgtctttta aattttcgat aacaccaata accgaaaagc
     8881 gttagcacta gcaatatacc tagaaggagt ataagtaatc gataaagatg gtattttttt
     8941 gtctgttcta tctttgaaga gacttcttct gtaaagggaa ctcgtcttcc tgtcactagt
     9001 aatcggtgag tgttcacggt gtaaggtgta caagtgataa gtgtgactag atcctgcttt
     9061 tctctaattg ctaatgtatt tgtttttgtt ggaaggacaa caattttctc aacgacttca
     9121 taagcgagca tccgaccata cacttcaaga tagaatcggt catcttgctc catttcttca
     9181 agatccgtaa agagtttttt ctcagcaata ccgctatggg cggtaatcac ggaatgtgta
     9241 ctctctcctc cagttggaaa agaggtgcct tgcaggactg tcgctcctct atctaacaaa
     9301 agatcattcg tttcatcaaa taaaggcaag ctaacattga ttttcggaat atagatggct
     9361 ccgatcatat gttgttcgta atattctttt cctggatttt ggacatttct aaccgcttgc
     9421 tcaaaaggat ctttgacttg tcccattcct gggattactg atgtatgagc aagcgtctga
     9481 tttttctttt catgcactgc taattgttgc tcatgttttt cttctttatc gcgttcaagc
     9541 tgcttttgat aattctcgat ccttctttga tccaaataat tgctgagagc atctgctaaa
     9601 aatggatatg taaaaactgc agctccggca agaaacatca ctgccataaa taattgtaat
     9661 aaaagactga tttgggtttg aggtctatta cctattttct ttttcatttt cttcaccttc
     9721 ttatttaaaa aaactgcagc aacctttata aaaccgattg ctgcagctta tttttgttgc
     9781 ttatacttca gacttcattt tagatttacg gtaccagctg tacgctccaa tcatcaaact
     9841 tattccgatt agtaagaatg ccaagagccc gttcccacca gtagcaggaa gtgacccgcg
     9901 tttcatattc ggtactcttt ctggccctgg attttctact cctacgatct gaatttcttc
     9961 attatagctt ccataagaga tgataaattc agtaaaggct gcctcacctg ttggaagtac
    10021 ataaccttct ggcgccatgg tctctttcat ttgataggtt ccataatcta acccttgaac
    10081 ctcaaagtat ccatttccat ctgcgacaaa ttctgttgct tgtccgcttg ttgcccactc
    10141 aattctatct gctcctgatt cataaacagc taaaggcgac tcccctttat aaaatattgc
    10201 gtattcagaa cggtcttcat tccacaattc gaatcttgca tctttaagca attcactgct
    10261 tgatgcatca tatttttcaa actttcttcc acctgttgtg actttctctg gcggctctac
    10321 tccttcttca taatcaaatt catcatttcg tccgatttca ataaccgctg tgttgttatg
    10381 gaaatcatcc gcttctagtt ctgtggaaac cttcaaatta tacgtgatcg ttaaatctcc
    10441 tccacgtgca tctgctaatc tacctaaagt atctactttg gctactccat tttcttctgt
    10501 caaaatcgtc acgacaaacc cgttgcttac tacttctact atataatctt gtccttttgt
    10561 taaaatcgtc tcgccggctc gcacttctat ttcctgatca taataagtta gaccaactgt
    10621 aggcgtatct gtgattttgt aatttttgat aacagcgctt ccgttttcaa ggacagaatc
    10681 gatgaaataa ggaataggtg ctgtgatcgt gtaagaagcc gtttttcctc tttctagatc
    10741 aatataagaa atcgtttctt gttctccagc ttcattaata atcgttactt gtctaaggtc
    10801 gctttcctct acattcatct gtttatctgc ttctctgatt tcgtttttcg gatacaaatg
    10861 cacatctgta ttgtatgtgt ctttccatgt agaaccatcc cacacgccat ccaccatatc
    10921 aggcatcatc actggcatca taacaaccat tggagacgcg attctggaaa tatgagctgg
    10981 cgaataagtt tctaagaaaa gatagacttt atctctagaa gaaggtgctt cttccgtcac
    11041 ttggacggta gagaataccg cttctccagc ttcattcgtt gtttgtttgt caatacttgt
    11101 cagtcgatat tttaaaaacc aactttctgt gtgccgtttt tgaatccatt caatcgcttc
    11161 ggcagaatta agaccgtctt ctcgttccgg tgttaaagga ttatctcgaa tcaaatcgta
    11221 atatacttcc gttacgtcaa acaaatcaaa atcgactcct ggaatatttt cttcaccaaa
    11281 atccgtagaa accaatccgc tattcggtcg ttcttccgga acagatgaga aacctttttt
    11341 gtgtaatgta atcgtcactt cacttggttt ttgtgcgact tcttcggctt tgactagttt
    11401 tccgttcccg aaaatcccta ttcccgcagt aacgagtaac agtacactca ttcccgtgac
    11461 aatcattttt ttattcattt ttttctcccc gttctttttt tatt
//
LOCUS       DAFTHM010000083        11412 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFTHM010000083 DAFTHM010000000
VERSION     DAFTHM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.083"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..914)
                     /locus_tag="L7C88_002144"
     CDS             complement(<1..914)
                     /locus_tag="L7C88_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBP9558953.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="L7C88_002145"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="L7C88_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBP9558954.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="L7C88_002146"
     CDS             2006..2176
                     /locus_tag="L7C88_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558955.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEETALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2391..3650
                     /gene="lysA"
                     /locus_tag="L7C88_002147"
     CDS             2391..3650
                     /gene="lysA"
                     /locus_tag="L7C88_002147"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBP9558956.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3637..4437
                     /gene="dapF"
                     /locus_tag="L7C88_002148"
     CDS             3637..4437
                     /gene="dapF"
                     /locus_tag="L7C88_002148"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBP9558957.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDTDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4440..5321
                     /locus_tag="L7C88_002149"
     CDS             4440..5321
                     /locus_tag="L7C88_002149"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBP9558958.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5318..6034
                     /locus_tag="L7C88_002150"
     CDS             5318..6034
                     /locus_tag="L7C88_002150"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBP9558959.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6040..6735
                     /gene="dapD"
                     /locus_tag="L7C88_002151"
     CDS             6040..6735
                     /gene="dapD"
                     /locus_tag="L7C88_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBP9558960.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6751..7752
                     /locus_tag="L7C88_002152"
     CDS             6751..7752
                     /locus_tag="L7C88_002152"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBP9558961.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7749..9110
                     /locus_tag="L7C88_002153"
     CDS             7749..9110
                     /locus_tag="L7C88_002153"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBP9558962.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9070..10221
                     /locus_tag="L7C88_002154"
     CDS             9070..10221
                     /locus_tag="L7C88_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBP9558963.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSGAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10196..11365
                     /locus_tag="L7C88_002155"
     CDS             10196..11365
                     /locus_tag="L7C88_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBP9558964.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
BASE COUNT         3768 a         2000 c         2498 g         3146 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaagaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaatag tgttgaattt atgtttttat gtataaatag cttctaatag
     2221 ttcgggtatt ttgtttttat aaccattttt attcttattt ttaaaaaaat atttcgaaat
     2281 atactagaca attcagaaaa ttttgtttaa tattattcca ataaaattca aatctttatc
     2341 aaatgaaatt ccaataaaaa cggaaaaaaa gtgaaaagag gaatgaaaaa atgacagaat
     2401 tgataattgg cggagtcaca gcaagcacat tggcagaaaa gtataagaca cctctgtatg
     2461 tgtatgatga agaaaagatg agacaaacga tgctgtcatt caagcgaggc tttgtatcga
     2521 aacgttttga tacaaaagtg ctttacgcct ctaaagcatt ccaaacgatt gagatgctgc
     2581 atttagttcg tgaatatgga ttcgggctag atgttgtcag tggtggggaa atctataccg
     2641 ctttgcaagc tgattttcct agagatacta tctacttcca tggtaacaac aagacgccag
     2701 aggaactgat ctatgcactt gaaaatgatt tgttgcatat tgttgccgat aatttgatgg
     2761 aagttgaatt attagcagaa ttaagccaac gctatttaaa aaaaatctgt atcatgcttc
     2821 ggttgaatgt cggagtagaa gcacatactc atgaatatat cgtcactgcg catattgatt
     2881 caaaattcgg catgagctat gaaagtaaag agtgccaaca agcccttcag ttgataaaag
     2941 aaagcagcta tctagagtta gaaggatttc atgctcatat cgggtcacaa atttttgatg
     3001 ttactgcttg gttagctgaa atcgacaaat tgacgaatta cttaaccgat tttgaccaac
     3061 ctctttcctt gaatcttggc ggagggtttg ggattcgtta tacacaaaat gatcagccga
     3121 tcccagtcga agaggcacta aaaaaactga ttgaatatac ggaagaagct ttggaaaaac
     3181 gaaaactgac cattcgtcaa ttactgatcg aaccgggtag aagtattgtt ggagaagctg
     3241 gtacaacact atacacgatt ggtttcatca aaaagacacc acataaaaaa tattactttg
     3301 tagatggcgg gatgacagat aatatccgtc cagctctgta tcaggcagaa tacgattgtg
     3361 atttagcagc aaaactgtcg gaagaaaaaa cagagaaagt gacgattgca ggaaaaatgt
     3421 gtgaatcagg cgatgtggta attaaagaag cttatttgcc gaaagcagaa tcgggtgatc
     3481 ttttagctgt ttattccacg ggagcttatg gatactcgat gagcagcaac tacaatcgag
     3541 cgacacgacc agcagttgtt tttgtcaata atggccaatc aagactgatt gttcgcagac
     3601 aagcattttc tgatctacta aggggggaag tttcctatga tccttcataa atataatggc
     3661 tgcggaaatg attttatctt attagattac gcagaagaca cagattatag tcaattagcc
     3721 gcttctttat gcacaaaaga aaaatatgat acagacggat tgatcgccgt aaaaatcgat
     3781 ccgttggaaa tgatctatta caacaaagat ggcagccgcg cgccgatgtg cggaaatggc
     3841 attcgctgtt ttgctcgata cgtaaatgat cagaacatga tgaatgaaca ggaattcaac
     3901 gtagagacat tagcaggcac aagaaaaatt acggtgttgg atccctcacc tttttattgc
     3961 agcgtagata tgggagtgcc agatgattct ccggaaaaaa tcaaagctaa tcaaacttat
     4021 ccaataaaaa accaggaaat agagatcaat ggtgaaaaag taacgatcac tagtttattt
     4081 ttaggaacga ttcatacagt tgtttttgtt gaaaatgcgc gtgaggaagt ctggagaaaa
     4141 agaggtgaac tgatctgtca tcatcctttg ttcaaagaaa aaaccaatgt caactttgta
     4201 gaagtagtca atgaacaaga attgatcgtc cgtacctatg aaagaggagt aggttggaca
     4261 cttgcttgcg gtacaggttg ctgtgcctct tatgtggttg ctaaggaaac tgggaaaatt
     4321 tcagcagatc aggtagttgt tcacttggaa caaggagact tgatgatctc tggtgaggat
     4381 gcgatacaaa tggctggccc agcagttcat gaatggacaa gaatattgga ggaatgaaga
     4441 tgataaaagg ttcgatcgtg gcgctgatca cgccgatgaa tgaagaggga tcagtagatt
     4501 atgctggttt ggaaaaattg atccaattcc atttagatga acaaacagat ggattattag
     4561 ttttaggtac aacaggagaa tcttctacgc tcacacaatc tgaggaggag cagatccttc
     4621 aactgacagt aaagaaagtg gctggccgtg tgccggtgat tgcaggagct ggaacgaata
     4681 atacgaaaga aacgattgaa aaagcgaagc attttgcttc tttgggggca gacgcacttt
     4741 tggtcatcac cccttactac aacaaaacaa gtgatgcagg actagctgct cattttacag
     4801 caattgcaga agcctcaccg attccgctta ttttgtataa tgttccttct agaacaggca
     4861 tgtcgattcc aatccatgta ttagtaaatt tagcagaaca tcctaatatc attggtttga
     4921 aagaagcctc aggagatatg gcttatgtga tggatgccgc tcggttgatt ggagaagaat
     4981 tcttccttta cagtggaaat gatgatttga tcctaccagt aatgagtgta ggaggaagcg
     5041 gtgtaataag tgtatgggcg aatatccaac ctaaaatagt ccatgaatta gtaaaagata
     5101 cgcaggacgg aagatggcag caagcaaaag aaaagcaatt aaatgcactt gaactgatcc
     5161 atgccttgtt cagtgagacc aatcctattc ctgtcaaagc agccatgtca ttattagact
     5221 taccttccgg acctctacgc ctgcctttag tttctctttc aaaagagaaa aagaaacaat
     5281 tagctcagct tttgttaaaa gaaaggacgg ttgaaaaatg aaaatcggac tgattggcag
     5341 tggacagatg ggaaatagag tcgaagaagt tgcacaagaa agaggagata cggtccttct
     5401 tttacggacg gcacctaaag aagcaactac gcttgctttt acggaactgc cagaactgct
     5461 tattgatttt tctcatccag ataatttaga gaaaatcctt tcgtatagct tatcatatca
     5521 acttccgtta gtcattggca cgacaggtta tacacaatca cagttccaag aaataaaaga
     5581 acatgccaaa catgtacctg tgatgtatag tgctaatttt tcgttcggca tcatggtgat
     5641 gaatcaacta atcaagcaag cagctgcaat gttgcaaggc tggcagatcg aactgattga
     5701 aaaacatcat agtcgtaaaa aagatgcacc atctggtact gcaaatatgc tgcttcaaac
     5761 aatccaagaa gtgcaaaagc tgcagcccgt atacaactgg caagggaaaa aaagagaaga
     5821 aaaccaaatt ggtgtacaca gtattcgtgc aggttcttta cctggtgaac atgatgtatt
     5881 gtttgctgct actgatgaaa tatttacgat caaacatgaa tctttttcta atcgaatctt
     5941 tgctgcaggc gcagtagaag cagcggactg gttgaaagat cagtcaccag gttattacaa
     6001 attagaagat ttattaatgg acaaaggggt gtaaaaaacg tggaagctca agaaatcatc
     6061 cgctacattc aaacggcatc taaaaagacg cctgtgaaag tctatctgaa tgtaaccgag
     6121 ccaatcgaat ttaaagaaag taaagttttt ggtgaaggaa gcagcttcgt tgtttttggt
     6181 gactatgaga cgattgctcc ggttttagaa gctgaatcag aaaaaatcat tgaaatcgaa
     6241 atcgaaactg ctgcaagata cagcgcagtt cctttgctag atattaaaaa aattaatgct
     6301 cgtatcgaac caggtgctat tatcagagat caagtgtcaa tcggcaacaa tgccgtgatc
     6361 atgatgggag cgattatcaa tattggtgca gtaatcggtg aaaacacgat gattgatatg
     6421 ggtgctgtct taggtggacg agcgacagtg ggcaaaaact gccatattgg tgcaggagct
     6481 gtcttagcag gtgtgatcga accagcatcg gccaaaccgg ttatcgtaga agacggcgta
     6541 ctggtaggtg cgaatgcagt gattgttgaa ggtgtccata tcggaaaaga tgcagtcgtg
     6601 gcagcaggag cagtggtttt agaagatgtg gcagcagaaa ctgttgtcgg tggaatacct
     6661 gcacgtgtat taaaaataag tgatgatcag acaaaagaaa atacagcatt gattgctgcg
     6721 ttacgcgaat tatagaggag atggagaaaa atgcgcgaaa tagatacctg tattgtgggg
     6781 gcaaccggat tagtcggcca aacgatgctc aaagtgttag aagaatatga ttttccagta
     6841 ggacgattga aattattagc ttcaaaacgt tcagccggta aagtttgtgt attcaagaaa
     6901 aagaaacaca ctgtacagga attgacagaa acttcatttg aaggatatga tttagcgcta
     6961 ttttctgcag gtgcttctgt atccaaagag tttgcgccaa tcgcacgaag tcagggacta
     7021 tttgtcatag ataattcctc agcatggcgg gaagattcgg atattccatt aatcgttcca
     7081 gaggtcaatc tggaagacta tacattgaat cggctgattg caaatccaaa ttgttcaacc
     7141 attcaagcgg tacttccgct taaagcttta caagaagcct ttggtatcca gcgagtcaat
     7201 tattcgacct atcaagcagt ttctggttcc gggcaaaaag gcattgaaga tcttcatcgt
     7261 acgcaaaatg acgaggaacc agttttgtat ccttataata ttagccaaac ggtgattccg
     7321 gaaatcgatc agcctttgga aaatgggtat acaaaagaag aacagaaaat gataaatgag
     7381 acccgtaaga ttctgcatca gcctgctttg ccagtatcag caacctgcgt acgtgtgcca
     7441 atcgaaaatg gacatggagt ctctgtggca gttcaactgc aaaaagagtt tacgacggaa
     7501 gaaattagag agtgtctcag ccagtttcca gggattcaat tagaagatga tctagcagca
     7561 cataaatatc cgacgagcat tcttgctaga ggaacagata tggtttatgt tgggaggatc
     7621 agaaaagaca cttctttaga gaacggattg ttgttctata cgactgccga taacatacgc
     7681 aaaggagccg ctgcgaatgc cgtacagatt gctgcagctt taatgcagaa aatagcggag
     7741 gtggcaagat gagtaatacg ctgaaagtag cgaaattcgg cggaacatcg atgtctcatg
     7801 aagagcaatt caaaaaagtc cgtacaattg ttctttcaga tcccaatcgc caagtgatcg
     7861 ttgtttctgc tttaggcaaa cgtacgtcag atgatgacaa agtaacagac ttactttatt
     7921 tgatttatgc ttaccttcag catcatgttg attggacacc cctttggaaa aggatttgtg
     7981 atcgtttcat tcaagtaaga gatgttcttg ccctgcagtt acctattgaa gatgaactag
     8041 cacgcataca gaaacaactg gaagacgaaa agataactga agattattta gtaagtagag
     8101 gtgaatatct gactgctcaa ctgatggctg agtatcttgg ttaccagttt attgacgcaa
     8161 aagacctgat tttctttgac tatgatggga aaatcgatca ggaaaaaaca gcacaggaaa
     8221 tcacaaaagc atttaaaaga tatccgaaaa tggttgttcc agggttttac ggggcgaacc
     8281 ctgcaggaaa agaaaaatta ttgggccgtg ggggaagcga cattaccggc gcgatactgg
     8341 cgaagatgtt gcaagcggaa agttatgaga attggacgga tgtttcagga atcatgatgg
     8401 ctgatccgcg aatcatcgat catcctaaaa tcatcgagga aatctctttt agagaactga
     8461 gagagatggc ttatatgggg gctaacgttc ttcatgaagc agctgttttc ccagttcaag
     8521 aggctgatat ccccatccaa ataaaaaata ccaatgatcc tttcgctcaa gggacaaaaa
     8581 tatcgaatca cgaaatagaa aaggaaaatg gactgacagg aatagctgga cgcaaggatt
     8641 ttctttccat cactttattc aaacgtcata tgtccgatga aatcgggttt atctggaaag
     8701 caatgagcat ttttgctaaa catgagatat caatcgaaca tattccttca gggatcgaca
     8761 atatcggagt gatcgtctca gcagaagcga ttgccgataa gttatttctc atcacgaaag
     8821 aattaaaaga aacacttggc gtggaagaaa tcgtcgtgat cgaagactta gctttgatct
     8881 ctgtcgttgg gggtccgcat aaagaattga ttggattatc tgggaaagtg ttatcgatat
     8941 tgaacaaatt agaaattcgc acatcgatct tatcacaagg agcacaggag ttgaatctga
     9001 tcatcggtgt accgaataat caatatgaaa cagtagtgaa gggtatctat gaagggatgg
     9061 tgaatacgga tgctgaaaga atatcgaatg gcactccatc aaattcctga aatcgggttt
     9121 catgaattca agacaaaaaa atatttatat gaacaagtaa aaaacagcgg ggccgttatc
     9181 catgaaatcg gcgaaacagg actactcctt tattttgata atcagcaaga agaaacgatt
     9241 gcttttcgaa cagatatcga tgcactgcca gtcaaagaag aaacgaatct ctcttttgct
     9301 tctaagcatg aaggttatat gcatgcatgt ggtcatgacg gacatatggc gatgctttta
     9361 gggttgactg actttataac taaacacatt gaggatctta tttataatgt agtactgatc
     9421 tatcagccat cagaagaaat ttccggtggc gcacaaagcg ttattcagtc aggattgttg
     9481 gataaatatg aagtacaagc aatatttggc tttcatctat ggcctggact agctaaggga
     9541 gaagttttct ctcgaccagg acctttgatg gcacaaagca gtgaaacaga cattatcatt
     9601 aaaggccagt ctgcacatat tgcttctagt gaaaaaggaa tcgatagtct ggaggcagct
     9661 gtacgatttt tgaagaatgt ttatgatttt gaccggcaat taccggcaga gtggaatcat
     9721 ctaatgaaat ttggccaaat ccaaggtgga acgatccgca atgttttagc tggagaagtt
     9781 attgtatccg gaagtatccg ttcttacagt tcagatatgc aaaattattt gaagagggga
     9841 ttagaccatt tagcagaaca gtttcactct acagctacta tttcttttcg ctataatgac
     9901 ggctatccag ctgtaatcaa ccatagaggc ttatatgcag cactgttaga ttcaaacaaa
     9961 ctacatgaat tagatgctcc agttcttcaa gccgaagatt ttggcatata tacgcaacaa
    10021 tatccatgtg tatttttctt tttaggtgtc ggtgataccc ctgctttaca tgatccgacg
    10081 ttcgattttg atatggatgt tttagaaaat ggtgtagaat ggtacaaaac gattcttttt
    10141 acagaaaatc ttcttgtaaa aatcgatagc agttcaaaag aggagcgagt aaataatgat
    10201 gaatttatcc aatcgattta gtcctaggct ttctagaata gaagtatcaa aaatacgaca
    10261 attcgatcag caaatatcgt cgataccaga tgtgatcaaa ctcaccctgg gagaaccgga
    10321 ttttccaact cctgaacatg tcaagcaagc aggaatagca gcgattgaag aagacttttc
    10381 tcactatacc ggaatgagag gattagagga actgcgggaa gcggcttgta tatttcagca
    10441 acagcgttat ggattaactt atgatccgca aacggaagtt ttgacgacag ttggtgcaac
    10501 ggaagcgatt gcctctgcgt tgttatctgt tttggaagaa ggagacaagg ttcttattcc
    10561 agcgcctgct tattcaggat atcagccatt agtggaacta gctggtgctg aattgatccc
    10621 gatagatact tctgacacag ggtttgtctg tcagccggaa caatttgaac gagcatttga
    10681 acaatatgga tcagctgtca aagcagtcat tttaaactat cctaacaatc ctactgggac
    10741 gacattgtct gcaaaacaat tgaaagcaat cgctgaggtt ttaaaaaaat atccggtatt
    10801 tgttataagt gatgaagtat atgctgaatt gacttatagt ggaacgcata tgtccatagc
    10861 tacttatctt ccagaacaaa caatcgtgat aagcgggtta tccaagtcac atgcgatgac
    10921 tggttggcga gtgggcttta tttttgctca aaaagccctt attgacgaac taattaaagt
    10981 ccatcaatat ctggtgactg ccgctacaac gatgtcgcaa aaagctgcgg ctgaagcgct
    11041 aataaatggg gtgaaagata gcgagaatat gaaagagcaa tatcaaacac gaagagacta
    11101 tctggtccag caattggcgc ctttaggatt tgaagtgacc cagccaaacg gtgcatttta
    11161 cttgttttgc aaactcccag ctgccattca aactgactct tggcagtttt gtgtagaatt
    11221 agcggaacag gcaaaagttg cgtgtatccc aggaattgca tttggcccag aaggagaagg
    11281 ttatatccgg atttcttatg ctagcagcat ggaaaaatta catgaggcct gcaaacggat
    11341 caaagacttt ttaacagaac agtgattcat agattttatc aaaaaaacaa tcgttaattt
    11401 tgcggtatat tc
//
LOCUS       DAFTHM010000084        10870 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFTHM010000084 DAFTHM010000000
VERSION     DAFTHM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.084"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..435
                     /locus_tag="L7C88_002156"
     CDS             <1..435
                     /locus_tag="L7C88_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBP9558965.1"
                     /translation="VRGVFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIF
                     ISNAFDHRVADQSPITINLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLG
                     LYSAKKMLDVYENAELKIEFSKQNHYFFVEMYLASRKSKSAY"
     gene            757..984
                     /locus_tag="L7C88_002157"
     CDS             757..984
                     /locus_tag="L7C88_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBP9558966.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            1107..1433
                     /locus_tag="L7C88_002158"
     CDS             1107..1433
                     /locus_tag="L7C88_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBP9558967.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            1501..2214
                     /locus_tag="L7C88_002159"
     CDS             1501..2214
                     /locus_tag="L7C88_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBP9558968.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            2524..3375
                     /locus_tag="L7C88_002160"
     CDS             2524..3375
                     /locus_tag="L7C88_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBP9558969.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            3496..5361
                     /locus_tag="L7C88_002161"
     CDS             3496..5361
                     /locus_tag="L7C88_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBP9558970.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGKPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            5409..6818
                     /locus_tag="L7C88_002162"
     CDS             5409..6818
                     /locus_tag="L7C88_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBP9558971.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            6926..7627
                     /locus_tag="L7C88_002163"
     CDS             6926..7627
                     /locus_tag="L7C88_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBP9558972.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            7786..8265
                     /locus_tag="L7C88_002164"
                     /pseudo
     CDS             7786..8265
                     /locus_tag="L7C88_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            9113..9688
                     /locus_tag="L7C88_002165"
     CDS             9113..9688
                     /locus_tag="L7C88_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBP9558973.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            9688..10128
                     /locus_tag="L7C88_002166"
     CDS             9688..10128
                     /locus_tag="L7C88_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBP9558974.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            10144..10845
                     /locus_tag="L7C88_002167"
     CDS             10144..10845
                     /locus_tag="L7C88_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBP9558975.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         3680 a         1768 c         2378 g         3044 t
ORIGIN      
        1 gtcaggggtg tctttttaaa atttctagaa aaagcagaat cggagaaaat cccgatccaa
       61 gtagttattc ctgtcgaagt gaaaacaatc ccgattgatc tggttgtttt tattcgctgt
      121 ttatctattt ttatttctaa cgcattcgat catcgtgtag ccgatcagag tccgattacg
      181 atcaatctgc tggaagaaaa agagggatca cgttttagta tagcgaacaa ggcaaatcca
      241 acgaatttga cgctatcgga gatggtcaaa agaggaaaaa cctctaaaaa aaatggcggg
      301 ttaggtctat acagtgcgaa aaaaatgttg gatgtttacg aaaatgcaga actaaaaatc
      361 gaattttcaa aacagaatca ctattttttt gtagaaatgt atctggcatc tagaaagagc
      421 aaatcagcct actgacttac tgtcaaagga taagtttgag gaaagtctac acggagatag
      481 agacaacaac acagcatatt caaaagaaac agaagcgtga tgaccgttgt cacccttctg
      541 tttcttttgc tatgtagtta aacaaagtag ttgacacttc cgctacttag tattagtacg
      601 aaagtatact tcatgatact aagtagataa gaagtgaaaa gcggaaccca cgatcgtcaa
      661 aatgctaact gctttgctta caccagataa agggaagagc aatatcgctt attttaggcg
      721 tggagaagca agcaaatccc tacgatcaca aaaaaaatgc tgacccagca gttaagagag
      781 ttagaacaag atgaaagtat ccatcgaaaa gcctataacc aagtcccgcc taaagtagag
      841 tactcgctca ccgaagaagg aaaatcatta agagagattc tagtagcgtt gtctgtttgg
      901 gaagaagaac gtatcgaaaa acaaaaagcc tcaagggaag aagacacgct actgcataca
      961 catggtggct acctaaatta ttgattttct atgacattta ttttaaataa aagaaaacag
     1021 gagttttttt aaaagcatca tctatttttt atgtaaaaaa atggtatgat taatcaagta
     1081 agaagtgatt ggaagaaggc aagcaaatga atagtatgga aaaagtcaac cagtttagag
     1141 atgaacgtaa ttggcgacaa tttcataacg aaaaagattt ggctatctct atttctttgg
     1201 aagcatctga attgttagaa ctttttcaat ggaaaacgcc ggaagaagta aaagaaacac
     1261 aattagaacg aatcaaagaa gaactggcag atgtattgat ctattcatac atgatggcag
     1321 acaaccttca cctggatcta gatgagatca ttgaagaaaa attgatcaaa aataatttga
     1381 aatatcctgt agaaaaaagc gcaggtgtac gaaaaaaata cacagagttg tagaaatgtg
     1441 tcattcggct gttggaaaga gcaaaagaaa aacagtaaaa tgagtctgga gggagagaaa
     1501 atgaaaaaaa aaggaaaagc aaaaagatgg ctagtcaata tcctcttgtt cctcttgtta
     1561 ttagtaggac tagctttgat tttcaatgaa cagatcaagg attattttgt cagagagaca
     1621 ggagataaat atgctatagc gaatgtaaca aaagaagatc tgaaaaagaa taacgataaa
     1681 gatgtcagtt ttgactttga tgcggtagaa ccaatgacga cagaaggggt catgaggtcg
     1741 caaatgagag gaacagatct accagtgatt gctagtatcg cagtcccttc agtttcaatc
     1801 aatttaccgg ttttcaaagg cttggataat acgtcactac tttacggagc aggaacatta
     1861 tctccagatc aagaaatggg aaaaggaaat tatgccttag caagccatcg tgcaacgaac
     1921 cctgaattgc tgtttacacc gctagaaaat ttagagatgg gtgccaagat ctatttgaca
     1981 gatttagaaa atgtgtatac atacaaaaca ttttttaaag aaaaagttgc tcctacagat
     2041 acccaattac tgaatgaagt cgagggaaaa gaaattgtca cactaattac ttgtggcgac
     2101 atggacgccg tcacgcgact agttgtacaa ggagaactgg aaagtgttac atcgataaaa
     2161 gatgcgacag atgatatgag atctgctttc aatctagaga caaaaacatt ttaggatact
     2221 gggacataag tcgttacaga ttaaaaacag ccaaaggata tgaatcgata aggaaaaacc
     2281 aatttgctga aaaaaagaga aacgcaaaga ggtgcatctc tgatttggtt gttttctaga
     2341 tagacttgtg ttccagtttt tttatttttt atatgaaaag gcttgcataa ataaaaattc
     2401 gatggtatga tgattttgaa taagaaatgg attgttactg tacggcaggc aaaaccagaa
     2461 ttcagctaag aaacagtagg cgaattctag gtttttttat ttttcttgag agggcgaagc
     2521 aaaatgaaaa ttgataaaat tttgaataac aatgtcgtca tttcgaaaaa tggattcggg
     2581 gaagaagtcg tttgtatggg aaaaggacta gcttttcaaa aaaagattgg ggacgagatt
     2641 tcgccagaag cggtccaaaa agaatttgtt ttaagagatt cttttgctaa aaaccaattc
     2701 cagcagctga tggctgatat tccggcagag gagatcgaat gggtcaaaca agtagtcgaa
     2761 ctggctgaag ataaactaaa agttgaattt tcgcctaata tttatctgac attgaccgat
     2821 catcttcatt atgcgatcac acgagcaaaa gaaaatatcc aactgcctaa tccattatta
     2881 tttgaaacaa aaaaatttta tccgaaagaa tatcaagcag cgaaagaggc tcttttgttc
     2941 gtgaaacaaa agacgggtgt ggaactttct gaggatgaag ccggttttat tgcctttcat
     3001 tttgtgaata gccaacaagg aaacgaagac atgcaagtga cgatgaccgc taccacaatg
     3061 gtaagagata tactgagtat catcagtaaa ttcttcggca tcgtgttcga tgaagaatct
     3121 ttgaattatc agcgtatcat tactcatctg cagttttttg cccagcgtta tctcaaaggg
     3181 gaaggatctg acgagcaaga tgaatttctc tacgcattag ttcaaggaaa gtatccaaaa
     3241 gcgtttcatt gtgtcgaacg gatcaatgag tatcttcgac aaacgcaaaa acaggaaatg
     3301 gggatcgcag agcagattta tttaacgatt catattcaaa gagtagtaag tgagaaaaaa
     3361 agcatccaat cataaggatt gttactgtat ggcaggcaaa acctggattg aaaaaatagg
     3421 ttcacgaatg tttgtgactg tttttttcaa tctgggtttt tattttttaa ataaaaaaga
     3481 aagaaggaaa aaacaatgga taatcaagca gttggtcgtc gtgtatggga agcggtagga
     3541 ggacaaaaga atgtcaaaag tttagtacat tgtgctacgc ggttgcgatt cagattaaaa
     3601 gatgaatctt tagcagatac gcaaaagtta aaagaagacc cggacgtgat ccaagtcgta
     3661 caaagtggcg gtcagtatca agtagtgatt ggcagtaatg tagcagatgt ttatcaatcg
     3721 atcgtggatg aggaaggtct tgcagtttcg gaggatggaa aagaagagtc caaaaatatt
     3781 ttgaatcgtc tgatcgatat tatctctagt atatttacac cttttctagg ggcgatggca
     3841 gccgccgggg tattgaaagg attcttatca ttggcaacgg tgatgggctg gctgacagct
     3901 gatagcggta cttatcaaat attgtttgct gcagcagatg gtgtctttac cttcttacct
     3961 gtcatgcttg cttttacagc agctaaaaag ttcaaagcca accagttttt agcagtagca
     4021 attgctatgg cacttgtgta tccagctatc acagcagttg ctggtgcggg agaagctatc
     4081 agtttctttg ggatcccagt gattctttca ccatctggtt atacttcttc tgtcatacca
     4141 atcattctag ccgtatgggt tcaaagtaaa ttagagccat tcgtaaaaaa agtgattccg
     4201 caatttctgc aaatgatttt agttccgctt gtcgttttag tagtgatggt tccattaaca
     4261 tttcttgctt taggaccaat cgggacggtt gccggtaatg ctttaggcgg tctcttcaac
     4321 tcgatttatg gatttagtcc aatcgtagca ggtctaatca tgggaagttt atggcaagta
     4381 ttcgtgatgt tcggcatgca ttggggattc gtaccgatca tgtttttgaa tatcgaacaa
     4441 tatgggtttg atgtattgat gccaatgctt cttccagcca tcttggcaca aggtggggct
     4501 gctttagctg tagcattgcg aacaaaagat acgaaacttc gagcattagg gatttcttct
     4561 acagtgactt cgttatttgg aatcactgaa ccaactgtgt atggtgtgac attacctttg
     4621 aagaaaccat tcattgccgc ttgtatttct ggaggtattg gtggagctat tatcggattt
     4681 tccggagtaa aagctttctc cagcagtttg gtcagcttat tgacgattcc gactttcatt
     4741 aatacggtgg atggtgtaga gtcaaatgtg acagtagcag taatagctac aggaattgct
     4801 tttgttcttg cattcgtagg tacattgatt ttaggatttg acgaacaaac acaagacaat
     4861 caattagaaa acaaacatgc gaatgcagga aaaccgatta cttcagcacg gcatacctta
     4921 aaaagtcctt taacgggtaa agtactgcca ttgagtgaag taccagacca agttttttct
     4981 tctggcgtga tgggaaaagg tatcgctatt gatccagaag taggagaact agttgcacct
     5041 gcagacggag agatcacgac tatttttcca actggacatg ctgtagggat cacaacgact
     5101 gacggagcgg agattttgat tcatatcggg atggatacag tagaattaaa tgggaatggc
     5161 tttgagatct tagtcaaaca aggggatctc gtcaaagcag gagatttatt gattcgtttt
     5221 gacatcgaag caattagagc agctggctat agcgtaatca ctccagttgt cattacgaat
     5281 actgatgcat ttgccgatat acttgaatta gaccaaaaag agattattgc aaacgaagat
     5341 gttctggcaa ttgtaaaata aggaggaaat caggatgcaa tcacgttttt cagaaaaatt
     5401 tttatggggt ggagcaactg ctgccaaatc aattagaagg ggcttatgat cgagacggaa
     5461 aaggactatc cgttgcagat gctatgcctg gaggtaagca gcgctttgcg attatcggca
     5521 gtgaagaatt tgactggacg attgatcaag aaaaatatat ttacccgaat catcgaggaa
     5581 tcgatcatta cgatcgtttc aaagaagatc ttgccttgtt tgcggaaatg ggattcaaat
     5641 gttatcgttt ttcgattgcc tggacacgaa tttttccaaa tggagacgaa ggtactccta
     5701 acgaagcggg attagaattt tatgatcagc tgattgatga gtgcttaaaa tatgatattg
     5761 aacctgtgat cacgatttct cattacgaaa tgcctcttca tttggcaaaa gaatacggtg
     5821 gctggaaaaa tcgaaaactg atcgacttct atgaacgatt tgctcagaca gtattagaga
     5881 gatacagcag taaagtcaaa tattggatga ctttcaatga aatcaattcg gcctttcact
     5941 ttccagcttt aagtcaagga ttagtaaaaa gcaatggagc aggagagtac caaaatattt
     6001 tccaagcatg gcataatcaa ttcgttgcaa gtagcaaagc cgtaaaaatc ggccacgaat
     6061 tgcgttcgga tatccaaatc ggctgcatga ttatctatgc aacaacttac agcatcgatg
     6121 ccaatccagt caatcaggca gcaacaatga tccaaaacca agaattcaat tttttctgca
     6181 cggatgtcca agtacgtgga gaataccctg catacacagc gcgtacccat aaaaaatatg
     6241 gagtcgatcc ggaaaaatta gagcaaacgg aaaaagactt ccagttgcta aaagaatatc
     6301 cagtggacta catcggattt agttattata tgtctacggc aatcaatgag actgatccac
     6361 aagcagcaac ttcagaaggg aacttgctgg gaggagtaaa aaatccgttt cttgaggcaa
     6421 gtgaatgggg ctggcagatc gatccagaag ggctgagaat cgcattgaat gaattataca
     6481 atcgttacca gaaaccatta ttcattgttg aaaacggtct tggagccatt gatcatatgg
     6541 aagaggatgg cacgattatt gatgattatc ggatcgatta tttacgtcgt catatcgaag
     6601 cgatggctaa tgcagtagca gacggtgtag atttgatggg ctatacgcct tggggatgta
     6661 tcgatcttgt cagtgcatca acaggagaaa tgagtaaacg ttacggcttt atctatgtgg
     6721 atctagacga tgaaggaaat gggacactga atcgatcaaa gaaaaaatct tttgattggt
     6781 ataaagaagt aattgcctca aatggcgtaa acttgtaatt aaagcagctg aatgaaaaag
     6841 aacacacttc tcacatgtga tttgtgttct ttttttattt tttatgtgct attcttttag
     6901 taatagtaaa gcaaagggtg acgttatgaa aaggacacgt gtactatact tggaagtcgc
     6961 agataaaatt aaagaagata ttttctcagg aaaatatcca gtcggttcga tgttgccgac
     7021 agaaagtgaa ttagaagaac tgtttcaagt cagcaaaatc actgtccgaa aggcaatcga
     7081 actgctggca tcagatgaat atgtcgcaaa gaaaagtggt cgtgggacga cggttctaag
     7141 caatcgtcct tacaatcgat tatccaaagc ggcaagcttt acgcaaatct tggagaactc
     7201 ccgatatgaa gtccggaaag aaacgctgga tttgcaattg gtccatataa agaaggaaga
     7261 tcctttgttt tcctttttcg gtgagcaagc tgtttgtttt aagcgcttat attatttgaa
     7321 caatcagcct tatatttatt ttgttcatta tcttccacaa gaaatgatgc aattcagcag
     7381 agaagaattt ggcaaagaat ctttgtatcg tttgctgacg aaaaaaggat atactattga
     7441 ctcattttct gatgatttct cggcagtatt tttaacagaa gaagaacaag gaattctgaa
     7501 aacagacgca cagatcggca tcaaacggat acggaaatcg tctacgcaaa ttggggaaat
     7561 gattgaatat tcggaggcgg tctaccatac ggagctgcat ccttaccata ttgattatga
     7621 aacataaata aaaaaagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
     7681 aaacaaaaat agcttctcat atttttcgtt tggttaggct tattaccgca gatacacggc
     7741 tgtttctgga ttaccattta ttctggataa gggggtgtgg cacgattttc agaaggaatc
     7801 tatgaaccaa tcactgtatt gattttagct tcgatggtaa ccccattcgg cttgacgatc
     7861 gcttatttct tagggaaaat cattcgtaaa aatatactca atcgtcaaga aatcgataca
     7921 ttgaagaccg cttttcctat ggggatctgt cagatcacag agggatgttt ccctatcgta
     7981 ttgaacgact tggcacgcaa tgtcatagca acgggagtcg gtgggacagt aggtggcgga
     8041 ttaagcatgt tttggggcgc agatagccgt attccggcat cgggaatgtt tgcagtcgct
     8101 acgatgacca gaccatgggc attcattggt gcattgttag ctggttcttt tgtcacagga
     8161 ataaccattt tattattgaa aaaaccagta gatccgaatg cagaaatcat ccaagaagaa
     8221 aaagaggaag aagacatatc ttgggatgat ttgacaatta gttaggagag gcagaatgga
     8281 ttacaagaaa aaagtacaat agatgtacct tgagacagga atggtatgaa agaatcagag
     8341 ttagaaagaa tcgaatatac agattttggt ttaggagcga tcgaaactgt ccagagcatc
     8401 ggcaccctcc ttgaaatgac gatgaaggaa aaatgagaac ctttcgttgt cgaaagggtc
     8461 tggtatacct tatgtcgaag gaaaggaaac aaaaaaactt tcctgtacta ttccaaaaag
     8521 gaaagaaagt tattatacag taaaaaaaga aattattctt catgctagag atcagtacac
     8581 gttcgagccc aatatcaaac actagttcca ggcaggcgca acaggtgcgg ttatcactga
     8641 attttcttcc agcagtgacg attcaagtga tatttttaca aatccagcta tttatcgtta
     8701 acaaaaagat ttttaggaga agctgatgaa caaaaatgat caaattttga tcgtttagtt
     8761 cgtcggcttt tttatttaga gaaacatcat ttatcagtga aacataacac gagaacaaaa
     8821 tgattttttc gttaataaaa gaaacaagta tttgttgttt aaaataatac acgttattgg
     8881 catataggac gaaatcccag tatcttctat aagtaagtca tttcatatcg atgaaaacac
     8941 gttatttatt tttgttttat ctataaaatg gctgaaaaat gatttttttc taaatactat
     9001 atatagtggc gtctatccta tataccacta aaaaactaca aaatctagtc ttttatttta
     9061 aaaaaacacg tgtagaatga agatagactt ttgagttagg gagtgttttt ttatgaaact
     9121 tactgttttt tgcggttccc gttttggtaa taaagaaagt tacaaattta ttgcgcaaac
     9181 gttaggaaaa tacatggcac aagaagaaat cgaactggtt tacggtggtt catactccgg
     9241 gattatggga gtgattagta aaacagtact ggaaaataac ggaaaagtca caggtatcta
     9301 tccgaatggg ctttttgaaa ctgaattgcc tggaaaagat gttactacat ttattcctac
     9361 agaaacgatc gatgaaagaa aggtattatt atttgaaaag ggagatgctg tcctcgtttt
     9421 ccctggaggt ctaggtacat tggaggaatt ctcacaactt ctttcttgga tagcaatcgg
     9481 tctgacgccc gacaagccaa tcggaatatt gaatattggc ggttattaca gcggcttgca
     9541 acaattatta gaaacttttg caaaagagga ttttatggat aaaaaatggt tggatcaagt
     9601 aatcttttcc aacaatccat tggaactggt caatgaatta cgagcagtat ctattaaaaa
     9661 tcagttatta ttgaaggagg caaaataatg agtcaaatat atttagcagg accatttttt
     9721 tcagaggagc aaatcgatcg agtaagtcgt atcgaaaaag cgttggagga aaacaaaaca
     9781 gtcacaagtt tctactctcc acgtcatcac caagaaagca attatgaact attcagcgct
     9841 ggatgggcgc aggaagtata cgaaaaagat atggaagaac tgacaaatgc agaatttgtt
     9901 gttgctatcc ttgactttga gcatcaaaca atcgatccag gaacggctta cgaattaggt
     9961 gtggcaacta tgttgaaaaa accgatgatc attgtacaag aagagacggt acctacgaac
    10021 ttgatgatta cacaaagtct ccatacgtat ttaaaatcag accaagctgt acgtgaatat
    10081 gattttgaaa cattgcctgt tgaaacttac gtaggcgagt acttatagaa gaggaagggt
    10141 tgtatgtcag tgattttgat ttcaggaacg attggtgcag gtaagagcag tttgacggat
    10201 atgcttgcaa aagagattga ttctaaacca ttttatgaaa atgtcgaaga taacgaagta
    10261 ttgccgctct tttattcaaa tcctgagcag tacgcttttt tattgcaaat cttctttttg
    10321 aacaagcgat ttttagcaat gaaaaatgct ttagtgaacg atgacaatgt gctagaccga
    10381 tccatctatg aagatagcct gttgttccat ctaaacgctg atttaggtcg ggtaacggat
    10441 atcgaagtac agcagtacga tagcttatta gatacgatgc taaacgagtt agatgatgtt
    10501 gctccaaaaa aacggcctga tttgatggtc catatcaaag tttctttgga cacgatgcta
    10561 gaacgtatca aaaaacgtgg gcgtgactat gaacagctag aaagcgatga gacgttatat
    10621 acctattatg aaacgttgaa cacccgctat aatcaatggt atgaagattt tgatgtatgt
    10681 cctaaaatac aagtggatgg ggataaattc gattttgtag aaaatccaga agatgcaaaa
    10741 aaggtgatcc gtcagatcca agaaaaatta gctgaattgg aaggaaagcc tgctggaaaa
    10801 tattttacgg ataaccagca tgcaaaaggt caagaattag gctaaaaata aaaaaccaaa
    10861 cgacgggaaa
//
LOCUS       DAFTHM010000085        10833 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFTHM010000085 DAFTHM010000000
VERSION     DAFTHM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.085"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            14..592
                     /locus_tag="L7C88_002168"
     CDS             14..592
                     /locus_tag="L7C88_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBP9558976.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            592..1521
                     /locus_tag="L7C88_002169"
     CDS             592..1521
                     /locus_tag="L7C88_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9558977.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            1518..3254
                     /locus_tag="L7C88_002170"
     CDS             1518..3254
                     /locus_tag="L7C88_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBP9558978.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(3317..4153)
                     /gene="pheA"
                     /locus_tag="L7C88_002171"
     CDS             complement(3317..4153)
                     /gene="pheA"
                     /locus_tag="L7C88_002171"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBP9558979.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(4150..4659)
                     /locus_tag="L7C88_002172"
     CDS             complement(4150..4659)
                     /locus_tag="L7C88_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBP9558980.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(4652..5947)
                     /gene="aroA"
                     /locus_tag="L7C88_002173"
     CDS             complement(4652..5947)
                     /gene="aroA"
                     /locus_tag="L7C88_002173"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBP9558981.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(5960..7051)
                     /locus_tag="L7C88_002174"
     CDS             complement(5960..7051)
                     /locus_tag="L7C88_002174"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBP9558982.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(7068..8234)
                     /gene="aroC"
                     /locus_tag="L7C88_002175"
     CDS             complement(7068..8234)
                     /gene="aroC"
                     /locus_tag="L7C88_002175"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBP9558983.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(8236..9300)
                     /gene="aroB"
                     /locus_tag="L7C88_002176"
     CDS             complement(8236..9300)
                     /gene="aroB"
                     /locus_tag="L7C88_002176"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBP9558984.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(9333..10355)
                     /gene="aroF"
                     /locus_tag="L7C88_002177"
     CDS             complement(9333..10355)
                     /gene="aroF"
                     /locus_tag="L7C88_002177"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBP9558985.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
BASE COUNT         3006 a         2392 c         1997 g         3438 t
ORIGIN      
        1 ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga cgattttaga
       61 tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag ggactttttc
      121 cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg tggtcacaga
      181 tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac agcaacaacc
      241 tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta aagattcttt
      301 taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt tttttctaaa
      361 ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc caatcaccaa
      421 tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa ctcgtccatt
      481 gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga aaaacggcca
      541 ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt gatggatagc
      601 gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg ctatgtaatc
      661 aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca agaagttttt
      721 ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa tgaaatattc
      781 caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa gaaccttgct
      841 tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag tagttattta
      901 acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa tttcttcacg
      961 acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat caatcgtttc
     1021 tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact ttctttgctc
     1081 aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt ttctattctt
     1141 gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa agacaatttc
     1201 gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga aatcaattta
     1261 caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat ctttactgaa
     1321 aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa agccaagctc
     1381 tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg ctataccgaa
     1441 ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc tcaataccgt
     1501 aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt gccaaacttc
     1561 tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg tttatttatc
     1621 atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg gtactaaaaa
     1681 agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta gccgcttttg
     1741 attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat atggaacagc
     1801 ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc catccaatga
     1861 tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga aacgacatgc
     1921 tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga gtgaatgaac
     1981 gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc gataagaaag
     2041 cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt tacggatatg
     2101 ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta gtaaatcctg
     2161 agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca aatgaagaaa
     2221 atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa acaacgattt
     2281 caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca ttactcagtc
     2341 aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt attttgtata
     2401 atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat cgacacacaa
     2461 aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc ttaaaagcta
     2521 ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc aatcaattgc
     2581 taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag aaacgttcgc
     2641 ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat acgctgacta
     2701 gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga atcgacagtt
     2761 tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca gtcaaggaag
     2821 aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc gaaagaatct
     2881 cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat atgatccttc
     2941 aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa ggattcatca
     3001 cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat aacggcgatg
     3061 gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc ggcatcagcc
     3121 atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg atccaatcag
     3181 tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa aatcaatcag
     3241 aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta aataaatcaa
     3301 tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga taacagccca
     3361 atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct actaatgtca
     3421 ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta gttttcaatg
     3481 gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc agcattttat
     3541 gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt actggagctg
     3601 actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg ttcaactcat
     3661 tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt tctaatgaag
     3721 caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca gcagttgttg
     3781 attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt tgtgattgtg
     3841 ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg cctaaaagct
     3901 gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt ttggaaagaa
     3961 gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg acagccagat
     4021 cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac gcagtcaatt
     4081 gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct ggccctagat
     4141 agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct tttctggtgt
     4201 ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa gtcgttgtgc
     4261 caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa tagacgtttc
     4321 atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa gaacaatcgg
     4381 ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac cagtcgcgat
     4441 aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc gaaagctttt
     4501 ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct caatctttgt
     4561 atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga ttgttgtttt
     4621 tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct cctgacacaa
     4681 gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca gctccttcta
     4741 gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg attcgatgat
     4801 cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg atcagaccgt
     4861 ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc gcatcaattc
     4921 tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt ccttctgctt
     4981 gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg atttctccac
     5041 caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat tggttctgtt
     5101 cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct aagataccag
     5161 ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga acaagaagtc
     5221 ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc tgttgaccag
     5281 ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc cttccgccaa
     5341 attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg attacggatg
     5401 tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca ctggctacag
     5461 gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt ggtagatact
     5521 ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc atcactcgcc
     5581 ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa ggctgtccag
     5641 ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca attgattcgg
     5701 ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct tcctcttctt
     5761 cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct tctgcgcgca
     5821 aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg ctgcgatggg
     5881 aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt tgttgtaata
     5941 attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta gacataatga
     6001 ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt attcctaaaa
     6061 tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct tttccgatca
     6121 gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat aaatcaaaaa
     6181 aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct tttgcccgat
     6241 tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct atttgtgtca
     6301 tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc aacaaaatat
     6361 ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag cctcctgctg
     6421 ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg actaagccag
     6481 ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt tctcttgctg
     6541 taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt tcaacatctt
     6601 ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt ttagcatctg
     6661 ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca aaccgaagat
     6721 ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc gtaatgatga
     6781 cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt gtacggacgg
     6841 gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca cttgcaacgt
     6901 aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta tcccaaccaa
     6961 ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca ccaatcagtc
     7021 caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta gtaatgtttc
     7081 aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc acttgggaat
     7141 tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac gacgctagct
     7201 gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc ttttgtatcg
     7261 atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac cccgcgaatg
     7321 acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt ggtacgtcgg
     7381 aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc tggtaatgaa
     7441 ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact aaccacagct
     7501 tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa tccagctgga
     7561 acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt ctttgtctga
     7621 tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac ttctgacgct
     7681 tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc ttggattcca
     7741 ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat tttcttggca
     7801 attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc aagcacattc
     7861 cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc tggacgcgga
     7921 cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga catgacagtt
     7981 gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc aattgttttg
     8041 ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat ccttcctcct
     8101 ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc tgacagaggt
     8161 aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga ttctcccgca
     8221 gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg tgggaacagg
     8281 aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc ttcctcttgc
     8341 tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat cgtacgtaat
     8401 cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag ttggagacaa
     8461 gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc cttctccatg
     8521 actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat gaccaaaatt
     8581 taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc gtttgatttc
     8641 caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt ctttcagctc
     8701 gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga tttcagcgat
     8761 tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa tcaatacacc
     8821 agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga ctgctgtctt
     8881 cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa cgaaatggat
     8941 cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc ctccaccaag
     9001 tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt ataactcagc
     9061 tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga ctggttcaaa
     9121 attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa cgtttgtatc
     9181 agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc cagcctgttc
     9241 tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta cagtaagcat
     9301 tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat cttttccatt
     9361 gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc attcaacgat
     9421 tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat catgccatct
     9481 gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat tcctgtacca
     9541 tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg gacagcactt
     9601 aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc gataaaaatg
     9661 acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc attgatcgta
     9721 ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc agatagcagt
     9781 ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc agccaccata
     9841 tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc atcagccgct
     9901 tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg agaagtacgt
     9961 ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat tcgcgcacat
    10021 tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac gaaactgccg
    10081 tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa ttctcgagaa
    10141 gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata gcgtgtaaat
    10201 gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg ttctgttcct
    10261 tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt ttttatttgt
    10321 tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt cttttgttta
    10381 cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt aattcctact
    10441 aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat gacccagata
    10501 atcaacaaaa aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc ttcaacgagc
    10561 cttaaaaagc gctgcaaaaa tataaaatag ccactataga tgaatttctc tacgtggctg
    10621 taagtcgtgt ttaaaaatct ttagccatca tagatacaaa cctggtttgt ttgtacccac
    10681 gaagtcatga atacaaacct atctaaaata gctaaagtaa tacgtattca gttttgtaag
    10741 ttttctagat ttcataaaaa atcgctccaa actgatgtaa gaattgtacc tagtatagac
    10801 ataaaaaaat cgactgtcaa tcatttttat gaa
//
LOCUS       DAFTHM010000086        10792 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFTHM010000086 DAFTHM010000000
VERSION     DAFTHM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10792
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.086"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            346..552
                     /locus_tag="L7C88_002178"
     CDS             346..552
                     /locus_tag="L7C88_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBP9558986.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(754..1755)
                     /locus_tag="L7C88_002179"
     CDS             complement(754..1755)
                     /locus_tag="L7C88_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBP9558987.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1760..3673)
                     /locus_tag="L7C88_002180"
     CDS             complement(1760..3673)
                     /locus_tag="L7C88_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBP9558988.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(3841..4347)
                     /locus_tag="L7C88_002181"
     CDS             complement(3841..4347)
                     /locus_tag="L7C88_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBP9558989.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4507..4947
                     /locus_tag="L7C88_002182"
     CDS             4507..4947
                     /locus_tag="L7C88_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBP9558990.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            5106..6446
                     /locus_tag="L7C88_002183"
     CDS             5106..6446
                     /locus_tag="L7C88_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBP9558991.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(6515..7672)
                     /locus_tag="L7C88_002184"
     CDS             complement(6515..7672)
                     /locus_tag="L7C88_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9558992.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(7675..8031)
                     /locus_tag="L7C88_002185"
     CDS             complement(7675..8031)
                     /locus_tag="L7C88_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9558993.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(8329..9303)
                     /gene="sgrA"
                     /locus_tag="L7C88_002186"
     CDS             complement(8329..9303)
                     /gene="sgrA"
                     /locus_tag="L7C88_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBP9558994.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(9499..10338)
                     /locus_tag="L7C88_002187"
     CDS             complement(9499..10338)
                     /locus_tag="L7C88_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBP9558995.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            10523..>10792
                     /locus_tag="L7C88_002188"
     CDS             10523..>10792
                     /locus_tag="L7C88_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HBP9558996.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIK"
BASE COUNT         3167 a         2218 c         1683 g         3724 t
ORIGIN      
        1 actggctttt ggcctcattt taggttatca tttgtaattt tatttcacag ttgatatgat
       61 tgttatgtaa aataaaaaag tttaggatac atcgaatttt tggggaaatt cttttggggg
      121 tatcctaaat cttttctatt atattcccat attttctatt attggtctag acgtatgatg
      181 gtaaactttg tacctatctg attgctgaat cattaattgc ttatcattag ccatctttgt
      241 ttcaagttcg ctagatgatc attttattca catcctaaca aacttgtcac atttatagat
      301 tcttaatcta tttatcatac aattataaaa aaggaggtgc tgcttatgaa agctatccat
      361 atttctttgc tttttttcgc tagtgcattg attttatttg ctattcatct ttgttcccag
      421 ccttatatca ataacaacgg aatattagtg gaaccagcat tcttttgctt accactcggc
      481 tttttgtccc ttcttgcctc cgcaggcttc ggatttgttg ctttttttaa acgatcaaaa
      541 caacaaatct gacttataaa atttacgtaa aagagatcgt gacaataatc gtgtgatatt
      601 cccaaatttc gaataaaagg tgccccttgc catctctaac tcctcagtca caagttacaa
      661 tattcataaa ccatgaaaag cttgtttatt gaaattgctc cttgtgactt ggagctaagt
      721 gacagattac aacctctttt gcatcataag actttactcc ttgaaaaaca ttactaactt
      781 ttgatatgtt tcttgcgctt gtttattgct gaaatcaaac tgatattcat ggttcaaaac
      841 agcatttttc tccgcataat ctacttttgt gactttcacc cccgctttct caaatacaga
      901 agttacttct tccatttgtt tcgtaaacgt atttgtattt ccatccgtta agaatgtgtt
      961 ttgcgtccaa cgatccgcat gtctgaccaa ggctaaactt ttgaccttct ctgattgttc
     1021 aaagtcctta ttatcaaagt aagcccatcc acatttttca taaagaaagc tagagatttt
     1081 atcacttact tgagtaagtg cagaaggatc caacagacca gacaaagaaa taaacttcgt
     1141 aatctgcttg ttctccaaag tcggatcaag atgatcagct tttttaattt cttcattttg
     1201 aagtgctaac aaatattctc cactaatttg tgcacctgcc gaatttccac caatcgaaat
     1261 attcgaccaa tctgcttgat cttttatctc ttttttagct gcttgaatgg cttcgttcaa
     1321 ttggataact ggtgtaggat gttttgcttc cggtgatcgt tcataatcta tatttacgat
     1381 gatttgctgc gtgtctgaac atagatattc caaataatca cgacaatcat ttttatcccc
     1441 tcctacatat gcgcctccat gcatccagaa aagaatcggt aattttttct tttccacttt
     1501 cggtgtgtag atatccatat tattattttt gtactttgaa ggataggata tttctttttt
     1561 tatatcgatt tgttcgattt tttgctggaa atcatctggt cgggcatata cttgttcttt
     1621 ttcacttgtg tcaaattgtt ttctaacaag caagctaatc ggctttggtg tgatttgatt
     1681 aatcaaaaat acagtgacta aaataactac gatgataact ggtactgcaa tcactattcg
     1741 cttgaaccat ttcattcatt taccctctct ttcttcgcca aatccatgtg ataatcgtgc
     1801 taacagataa aaatccacct gaataaatga gaagcgaatg tttcttttct ccagttttcg
     1861 gcaacattct tttttttgca tctgtctttt tttgtacttt cactgtcatc tgaatcggtt
     1921 gcgtatcatc acttgattga tcctctcgag gttcattctt tcccttattg tctgcattct
     1981 ctgtcggatc ttgctttttt ggtggagcta ctgggatttt tttgtaatag aaaataatag
     2041 ttggtatcgt ctcattaaaa atcccttcag tcggtccttc aacatttgct aattcgtatc
     2101 cttcgaatgt cttttgctct gtcatataat tttctccata agctccgtaa agctggattt
     2161 cgtcctggtc tttgagtaga cttttattgt tttcatccac atactttacg tttatctgat
     2221 catggaacac tactttcaaa aagtccgtta catgtttcgt gtaggcagca tggtcaactt
     2281 cctgtgcctt tccatgccct gctccttcta ctaataaaag atctttatac cctcctgata
     2341 actcatataa tttttgcgcg ttagacacag gtactacatc atctgctgtt ccatggataa
     2401 tcaatttagg caatgaatct gacattccaa tcgtaggtag agcagctttt gtatccaaat
     2461 gcatctcctg atcaaaatag tattgtttca aaaggcccat aaataaatct tcatgctctt
     2521 gatccccaat gatgtctaac tgatttttta tggcatccgg tagtgcgggg gctactgtct
     2581 ggctgtacgt aaaacgtagt tgttcatcaa ttgatgcaaa tccgcaattt tcaataattc
     2641 ctttgacatt gacaggaata tctttcgcta atacagacat catcgtagct gctcccatcg
     2701 aaccaccata aagtaaaatc ttttgagatg gccgctctcg aacttcttga tttatccagt
     2761 aaaggacgtc atctgactca tattgtccat aggtcacata atcgcctccg ctattaccag
     2821 tcgctctgga atcaacaaat aataaattat acccggcctt ataaaaatca ttgtattctt
     2881 ctgtaacgat cccgttattc caattccctc gaaatccgcc atggatcatg actgttttat
     2941 ctgaaccttg atcgacataa tatgcatata catccatcat tttgccatct tgtttgttta
     3001 gtacagtttg atgaagttgt tttgtatttg gatagaagcc tgtgttttct gtaggcgttg
     3061 tcccatcatc tgtacctcca agcatcgaca tcaacacact gttttttgca aaagcgatat
     3121 cgtacaatag ataagtagca atcagatgtt tgataatctc tttatctaca ccataatcat
     3181 taacagcaag ctcagtgact aataactcta ttaattttga cttgatgtct tctgttggtc
     3241 cattaagtat ttctgtcatc tgtttaccga agtaattcaa atattcttta ccattgaaat
     3301 tttcaccttt accgatatca tcattttctg tcccattctc tttgtcactt actttagcag
     3361 aagaggattc gtcgtttgac atttttgtag ctgttgcttc ttctgtttgt tggttatctg
     3421 tggtagcggt cgtttcttga tctgtgctag taacagatgt ctcaaccgtt gtttcagtat
     3481 ttgtttctgt ttgtgaagta ctcgatttcg tttcatttcc agcatcagta gtttctgtgg
     3541 tttctacctc ccgagattcc gattcggaag aaatgctctc tccatatact gtccattgcg
     3601 ggacgcttgt acttacagca aataagatga ccaacgctcc ctttaatact tgttttgttc
     3661 tcaagctatt cactcctttt tatgtttcta ggagaattat atgtaaacgc aaacattttt
     3721 tatacaaaaa ataaatggtt tatcccataa aaatagaaca ggattatttt ctcattttac
     3781 gtaataaagc agaatggata aaccagtatc cattctgctt tttttaaacg aagaaacaac
     3841 ttattgctcc aaaaatgtca gaaatcgttt atcccaaatt ttctcgtaaa aagcgattgt
     3901 ttcctttgct ttcataaaag gattatcata agttgtcgtt gctcctctac acatcataag
     3961 ctggtatcct aatccatgag caaacttcac agtcgtatct atacaatact ctgcttgtgc
     4021 cccacataat tcgatcgaat gacagtccaa ttcagttaat aaaacactca aattagtctt
     4081 ataaaatgaa ttcgcatggg tttttctcac aaaataactg tgctcaggaa tagataattc
     4141 cgacaatagc tcccatggtt ttgtttgtgg cactaattga gcatcttcgt gttgaacgaa
     4201 aataactggt ttcccaatcg tttcgtatgt tttgattctt ttattcacta atgctgtcac
     4261 tgtttctaat tcgtgtatcg gcgaagaatc aaaacatacc cctttttgta aatcgatcac
     4321 tactattgcg tcggctgtgt ttgacatact tgtgccttct ttcttttttc ttgatttaat
     4381 agtatttctt atctagctag ttccattata cgtgacaaca ttttcttatt ttacacctct
     4441 aaatggcact tttcgactat ttcttcatgt tattatttca taaatactta gctattggag
     4501 gaatgtatga tgattaaatt gtatacaggt tctggctgct cgtcttcaag acgcgcaaaa
     4561 cgttggctta tcgtccatga tataccgttt atcgaacaga acttaattcg tcaaccacta
     4621 accaaaaatg aatttatcca cttactaaaa ttgacaaaca acggcgtgac cgaaatgctc
     4681 tctactcatt ctattagtta taaaaatctt gttcacagaa tagatgaact cagtttgagt
     4741 gaactatata ttgagattcg tacatcccct tctttattga aaaaaccgat tatctacgac
     4801 caatctgcaa aacttttgac tggatttagc gaagataaaa tcaggatgtt cctttctaaa
     4861 actaaaagaa agcaagagct caacgaactc ttgctttctg gtcatcttgt cgattttaaa
     4921 gaaaataatc tttttgcaat gtcttaattt tggcataaac aatctgcttt tctggatcta
     4981 taatatctag tgttggtgac gccttctgtt gccaatactt tttctttttt ctaataaacg
     5041 caaacagaca ccttgaaatc ctttagaata aagtcgacga aaaccattca aaggagtgtt
     5101 tcaagatgtc ctattcagag tttaccaaag agttactaga tattctagac ctaaatctta
     5161 cctttcatga agatgccttt cgcaaagagc gcattaatga cgaaacatgt tttgtttttg
     5221 atggcacatt gacctatcaa ccagaggaat gcttccattg ccactatcaa aataagcaaa
     5281 cgatcattaa atggggctgg aaaaaagtat ccatcttatt gaatgatgtc agtaactaca
     5341 agaccattgt gcggattaac aaacagcgct tcaaatgtaa acactgtgga aagacttttt
     5401 tagcagaaga ttcagttagc gatcgtcgct gctccattgc ccgcagagtc aaacaagcca
     5461 ttcttgagct attaagtgag cctatttcta tgtctttgat tgcacgtatg aagcacattt
     5521 ctccgaccac tgtcattcga atacttcgca gccttcggcc taaaaccgtt tctttgaacc
     5581 agccgttacc agaagtggtg tgtttcgatg aattcaaatc ggtgaaaaac gtctcgggag
     5641 ccatgagctt tgtcatgatg gacggcaaga cccatcaact gattgatatt gtggaaaatc
     5701 ggcaactcaa tcctttacgc gactatttct tgcgctaccc tagaaaagtc cgtgaacaag
     5761 tacgtctagt ggtttcagat ttctatacac cctatcgcac attggtgaaa gagtgttttc
     5821 cgaatgcccg aatcgtcgcc gatcgctttc atattagcca acacatcggt cgggccttta
     5881 ccaaccaccg aattcaagta atgaagacct ttaaaaaagg ggatcgtcgg tcgaagcact
     5941 taaagaaata ctggagacta cttcaaaaga atgcgtggga attgaatggt cagcatcgct
     6001 actggcgtcc gtcatttcga gatcatctga cagaagcgga gatagtcgat cggctattat
     6061 attatgatga ctccttaaag cgaggctacg aagtctacca ggtttttctt tccgctatca
     6121 gaagacaaga tgttcctgaa ttcgtcgcgc tcctaaaaga agactacaag gagttgccag
     6181 agcactatca accagtgttc acgaccttca agaaatatcg aacagaaatc aaacgagcgt
     6241 tgcgagttcc ctattccaac ggccctatag aatgtttgaa caaccatatc aaagtactaa
     6301 aacgaattgc ctatggcttt agaaactttc aaaactaccg agaacgaatc tttttatatc
     6361 gaggaaaata tttcaagaaa actaagaaca ctacccaact gactaaagcc agaacaacaa
     6421 cacggctaga caagatagct gtctagccgt gtgagtatct cgattattct attgaatttc
     6481 ttcaccaaca ctcattgacg aagagccgct tttcttaatt aacgaaatcc aatttttcca
     6541 atatggatct atttttctca ttcctgattt ttatgatttc agctttcaga cgcgcccaat
     6601 cattttttgt aggttgtcca ttccagtaaa atatctgtgt attcgtttga tcatatgcct
     6661 ttttgtcgat aggataatcg ctaatgacaa tatcaggtaa ctgatcagcg gatgcactat
     6721 attttattgg gcgttcagtc atagataata tccttttctt tgcccataat tcctgtgttt
     6781 taccatactt tgattgaata tagaatatga caggttgttc gtgttttata aaaatatccc
     6841 tgactaacat acagtattga aaaatcaacc gtctgttctt ttcataataa gtattaagct
     6901 ctggaattct gcgagctacc ccactaaaaa actgttgcat gattggatac atcactggaa
     6961 atatatgctg aaaatctctg tcttctgctg attttccaaa agcatccacc ttcttttttg
     7021 tcccaaaaac ccttgaatac aaatggatca ttgccaaatt gacatataga taattttttt
     7081 ctgaagttgt aaaacaaatc ttgaagtttt tttcaaaatt ttctacaata gacgattcaa
     7141 tccagcccca actttcttgt actttatctg gagtatccaa caaatcttct tccaaatagg
     7201 tgttcattac accaaacata aaataaaggt aagcttgctc tgttggagtg atgtgattca
     7261 tcgaccagaa gtttgcttca aaaaaaggct ctagtatgta atgcgtaaac tcttcttttg
     7321 ttatcaatgg atgcacaaat ttgttcatct cttctgggac atacgtaatc gagtggcctt
     7381 gtttcattcg ttgcaacgaa attcttagta ggctgatcca tttctttcta tctatactac
     7441 gcgtatatgg cgcatgtttc gcaaattttt ctaatagttg acgtttattt tttatacttg
     7501 ataatatatc agaatgattt tcgtcgaatg actgccaata catcaagtga aaaaagtatc
     7561 ggatacggta ttcttctcct tctatcggat tacctttttt caagctgcaa gataaatgat
     7621 agtttttcaa aatagtatta agttctctta attttctttg aatcgtacgc aaacttatat
     7681 aattttttga ctaagatttt ctaaggattg ataagtacct ttgtaaagtg aatccagtaa
     7741 aatataacca atcgttccct ctaaaagtat agaataaact ttactcagta aaaactgaga
     7801 agaaaactcg acttttatca tcttgttttc tgaaagaaaa gataatttat attctggata
     7861 cctttcgcaa aacgattctg cttgttgaat caccgaattc atcttagcca gggtgtagtt
     7921 tagatctaaa gcgatatcct tcaccacata taatttctcg tctctttcat aacaatagtt
     7981 caaaaattga tatacttgcc tttcattgat atcaataaat tcttcaaaca aagtacatac
     8041 tcctttttat ctattattta gacttattcc gacagctaca tgaataacgt acaaatagat
     8101 tcgttactga tttttcagag atactaccat gcgcagtgtg cattgtcaat tattcttgct
     8161 cttattttcc atttgtgttc ctgttatttc ctgtttctca aatatgttag taaacaaaaa
     8221 tagatctggc aaagctacaa cttcgccagg caatacagca ctctcgaatg aaatattcac
     8281 tcaaaaatct atcgttttat tcaattttag atctgttgct tttattcttt atttcactcg
     8341 atggaagaga gaacgaaaat agcttgctcc tacaatcaaa atgagtaaca cacccatcca
     8401 tgtaattagc ttgttcaagg ttctactacc agtttctggt aaatcgcttt ttctattatc
     8461 tgtttctttc gctttttctt gatgatcaat tccacgagaa acaaaatcag gctgttttag
     8521 cacacttttt aggttgctcc ctgcatttct cttttgttcc ttagttggta tgataggtac
     8581 caaatcaagt tcattattta cttttcctgt gctgctttcg ctgctcgtgc ttcctgtgct
     8641 actctcacta ctcatgcttc ctgtgctact ttcactactc gtactctccg tactgctttc
     8701 gctgctcgtg cttcctgtgc tactttcact actcgtactc tccgtactgc tttcgctgct
     8761 cgtgttttct gtgctacttt cactgctcgt actctctgta ctgctttcac cgctcgtgtt
     8821 ttctgtactg ctttcactac ttgtgctatc cgtactgctt ggcggtccaa caactgtcca
     8881 actgcttggt ttcaaattct ccgtgatcgt catctgtcca tcataaaaaa caatcaaatc
     8941 aactttatct ttactcttga tctcatcaat cgatagttct gcagaaatca ttattgtata
     9001 ctcaatacca gcggtccatt gtacgtcttt taaataaact tccccaataa ctttttctga
     9061 acttccatta ccatcccaac catatgttag aacagcatgt acatcactag cattcacgct
     9121 tttgtttggt ttgactggaa tagtaatgac ttgttgtgtc atgtcataaa caatccgatc
     9181 agttttcaca gtaaatgaaa gattctcatt tgcccgttca tttgcagaag tactgattcc
     9241 aatcattgct gcaattatac tcagcccaag aataacaaat aatacggtcg ctgttttctt
     9301 catttctatc actctccata taattacctt ctatttgata aaggaattat ataaaatgaa
     9361 aatgatgaga acacgacagt cagttgtgaa aatctaacaa aagatgtcgt gtattcgctt
     9421 gaatttgttt actttttcgt ttaatcaatg acagacttaa aaaagcaaga ccgatatcag
     9481 ccttgctttc ttcatctttt attgataaac agcagtgtat ttcttcatcc gctttgtttt
     9541 atatgcatag agtaacaaac caacaatcaa gactaacaag aataatgtag ttgatataga
     9601 tgcttcagcc ccaaagtttc ccccagtaat tattgtattt tgcgattgga tcagagtgga
     9661 gaaaaaacct tgttcttgcg ttccgctgac tggtataccc aaaatagctc cttgtgtcca
     9721 attccaagta atatgagcac caatagccgt aaataaactt cctgtactgt agataagtgc
     9781 gctgaaaaag caacctgcta aaaagatatt gaaaactgcc agaaatgtca tgttaggatt
     9841 caatccgtgc aaaagagcaa ataatgcagc agatccaatc attgctatta acggaccaaa
     9901 tctaagcatc tgatgctgaa aaaagccacg gaataaaagc tcttctgatg cccccactgc
     9961 aataaataaa ataaaactcg ttatcagcgg cacaatgttt gcgtttcctg aatctaaccg
    10021 atacgccccc gtcaaatata atggactagt aataagcaga aacactccaa ttccaacaac
    10081 gagacctccc gctaaatacc cccagtcttt tcctcgaaca gaaacaccat aatcttctat
    10141 tctttttcct tcgaccttac tagcaagaaa taaagctagt aaaaaaacag ctaaatgtcc
    10201 gaccgtaccg gcaattgctc caatccattc actatttcca ataaacatat ccgcaagtgc
    10261 attattgaca agaattccta aaacaaaacc aactaagact attaaaacag atccaatcaa
    10321 ccgaataatc ctgatcatct ttcatccctc ctttatatta agtttaacaa cccttttctt
    10381 tcttgtctcg tgaaaactat gtaaatgttc tccatcatag agagaataga tttttacgaa
    10441 ctaagaatat ctacagcaac cttacgaaaa tgaaagactg tctccctaat tcttctgtta
    10501 gactgttttt aataaggaaa ggatgggaaa ttttttgaaa aaacaactac taattatgtg
    10561 cctttcagca tgtgcaattt tactattctc aggttgtagc aagtccaatg aaacgattgc
    10621 aacgtttaaa ggtggaacac ttacagttca ggatttttat gataacccaa aagttaaatc
    10681 aaataatcaa acactattaa aaaaaatgat tgtcttcaaa gcatttgatg atgtatacgg
    10741 aaaagagatt tcttcaaagg aagtaacaaa agaatataat gaacaaatca aa
//
LOCUS       DAFTHM010000087        10772 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFTHM010000087 DAFTHM010000000
VERSION     DAFTHM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.087"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(592..1983)
                     /locus_tag="L7C88_002189"
     CDS             complement(592..1983)
                     /locus_tag="L7C88_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBP9558997.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2196..2582)
                     /locus_tag="L7C88_002190"
     CDS             complement(2196..2582)
                     /locus_tag="L7C88_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBP9558998.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(2638..3261)
                     /locus_tag="L7C88_002191"
     CDS             complement(2638..3261)
                     /locus_tag="L7C88_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBP9558999.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3325..3993)
                     /locus_tag="L7C88_002192"
     CDS             complement(3325..3993)
                     /locus_tag="L7C88_002192"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBP9559000.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4005..4445)
                     /locus_tag="L7C88_002193"
     CDS             complement(4005..4445)
                     /locus_tag="L7C88_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559001.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4504..5176)
                     /locus_tag="L7C88_002194"
                     /pseudo
     CDS             complement(4504..5176)
                     /locus_tag="L7C88_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(5361..5759)
                     /locus_tag="L7C88_002195"
     CDS             complement(5361..5759)
                     /locus_tag="L7C88_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBP9559002.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(5756..6529)
                     /locus_tag="L7C88_002196"
     CDS             complement(5756..6529)
                     /locus_tag="L7C88_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBP9559003.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6526..7209)
                     /locus_tag="L7C88_002197"
     CDS             complement(6526..7209)
                     /locus_tag="L7C88_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBP9559004.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7376..8263)
                     /locus_tag="L7C88_002198"
     CDS             complement(7376..8263)
                     /locus_tag="L7C88_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9559005.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8260..9129)
                     /locus_tag="L7C88_002199"
     CDS             complement(8260..9129)
                     /locus_tag="L7C88_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9559006.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9266..10552)
                     /locus_tag="L7C88_002200"
     CDS             complement(9266..10552)
                     /locus_tag="L7C88_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBP9559007.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
BASE COUNT         3249 a         2328 c         1778 g         3417 t
ORIGIN      
        1 ctgttctaac attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag
       61 ctctcaacag aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt
      121 ttttgttatt tacgctttca cttttcggaa taaataatgt gtatttatat ggaataaata
      181 aaaaaagagg tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca
      241 actcctcggt cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct
      301 ctttgtgact cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag
      361 cttgcatctg cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg
      421 ctgttcttat tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag
      481 aagtagcttc tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa
      541 acttcttctt atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt
      601 cacatcgatc actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc
      661 acttgtcacg ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc
      721 gattaatggt tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc
      781 taaaacgatc agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact
      841 gattgttaca attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc
      901 tgctggtgcg acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc
      961 aatagacaaa ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt
     1021 tgtctgagtc tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa
     1081 gctcaatacc ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa
     1141 aatcagtgag tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt
     1201 acctaaattg acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa
     1261 tactccataa ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag
     1321 actgtcgact aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag
     1381 ataagcgatt ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact
     1441 acctgctaaa tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga
     1501 taagttttca actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc
     1561 tccttgtgtg aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa
     1621 tgctgcaata gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag
     1681 cttttcagaa actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat
     1741 aactagcatt tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga
     1801 ttgagtaacg actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat
     1861 accaactcct aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg
     1921 atagaacaca tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt
     1981 catttttctc ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga
     2041 gaatgattct tcaaccatcc tcctgaaaaa aattttttca gtgactttta tattttagac
     2101 gatttttatc gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg
     2161 atagctttaa tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa
     2221 ttcaatttta ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt
     2281 acgatatcga ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga
     2341 ccttcaattt tccgattgag gatatgattg atctgactca cacttccaga taaaacatat
     2401 gtatcaaaca ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag
     2461 ttttcgatcg tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg
     2521 ttcggcaatc tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc
     2581 atataatttt atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta
     2641 ctttttaatg atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc
     2701 cgggatctca cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt
     2761 ccctgcttcg atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg
     2821 aaaagtatcg atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc
     2881 gatccctact acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt
     2941 tgattctgtc aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc
     3001 cagtacttgt ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg
     3061 gtgaaataat tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt
     3121 agaatacttt ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt
     3181 tagtgcttgc catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa
     3241 gtcccatata taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct
     3301 ctcactttta gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc
     3361 tgctaatgta tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc
     3421 aggaacatct tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag
     3481 taaatcttgc cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg
     3541 attcactgtc atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata
     3601 tctgcggtca aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca
     3661 tgtttttact tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag
     3721 atccccataa tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc
     3781 catttcttct agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac
     3841 ggcatcgaat tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt
     3901 tcctttttct gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc
     3961 gctttcgcca tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg
     4021 aattttatac cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc
     4081 tgcttttgat gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact
     4141 tgctttttgt tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa
     4201 cgttgattct catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat
     4261 ccgaaaaaga cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa
     4321 ctaaagacaa gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt
     4381 ccctgcataa gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc
     4441 atcatattat ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa
     4501 gccttaattg gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc
     4561 aatcacaatc actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg
     4621 aagaaacagc ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat
     4681 caattgagga aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt
     4741 cgttttgatc agattccgtt tttttactga tcacttttaa aaagcttttt agaatctttt
     4801 gctgacgtct aaaaatagaa aaagaatttt cgtcatctat ttgataacgc atttgttttt
     4861 gcagttctgc tgcagtcaga tggatcttcc catcgtttgt atcgatcatt aaaccttctg
     4921 gaaacagttc aaccactgct cgatcccaag attcaagaga aagctcgata taatctttta
     4981 ctggtaattc caattctacc ttaaaaaagt gcaaaacagc cgacagccct tctgcttgat
     5041 agatttctcc taatgttagc ccctctagat ggaactctgg tgaaaaatgc agcaatgttt
     5101 tattttcctg caattgaaca tatagaaatg tagatcgctc aatcagagta tcttttaaaa
     5161 caactaaaaa attcattttt ctcccccttt tttcatcatt tttaaaatag catattttga
     5221 aaagaaagtc tgatgcttag agtagaattt cataaaaatt tactatttca taagtattca
     5281 cgagaaaaat acaaacaaaa aagcggaaat aacgctcatc cgccttcttg tttgtgttta
     5341 tttcctcttc aaacgcttgt ctatgattca gacttttctc tatcgttatt ttcatctaaa
     5401 agttcttgca ttccgataat ttctcgatat tgatgaatct tagtgatacc aatgactttg
     5461 tctacatcaa tactaaaaca aataccatta cctggaatat cgatgttgat gccttgacca
     5521 atcgcatcca ttactttatt cgtcaaacta tcgggtacta atgtcaacac aatatctttt
     5581 tctggcgaaa tgtccaaacc taaaaatttc cctgaatcat gtacaccaga acctcttcca
     5641 tgtaagatcg ttccgcctgc tgcacctgct tcttttgaaa agtcgataac atcttcgccc
     5701 attcctccgt caacgatcgt cacaatcatg tgaagattca atgctacaag atctttcatt
     5761 tgctttcccc caatttttgc aatctttctt tttcgattct gtctttttca tcttttcgtt
     5821 tataaatata tcctagtact aaagtggata atattggtgt caatgcaatc attgcaacca
     5881 caccaaaccc gtcaatgatc ggatctcttc cttcaatttg tgcagcgatt gccacgctca
     5941 ttgataaaat aaatgtcgaa cacatcgggc ccgttgctac tccaccgtta tcaaaagcca
     6001 ttgctaaaaa gatcttgtcc acttttcgtc ctaaaataaa tgctagcccg tatcctggga
     6061 tcaagaaata ataaagagag aatccgacga gcaaacgcca catagacaat cctactgctg
     6121 cgccgatccc aattgaaatt accatcagca tgattttcga tcggattctc ccctcgctca
     6181 attcttcaac ctgtttgatc attacatgaa tcgccggctc agcaaaccct actaagaacc
     6241 ccattaaaaa gccaagggga accagtatat aattgtaagg caatcccgca atagcactgc
     6301 ctaaatgctg tcctaccggt acataagcca tattgactcc gtgcaggaaa aggatcaacc
     6361 caatagtcgt tatcaagaaa cctttcataa tgtcaaagaa acgctttttg cgcatacgaa
     6421 aactaatgat attcattaaa acaaatagga ttacgatagg tgccactgcc aaaatgactt
     6481 ccatggtaac gatttcgatt ccatctatca cttgctgcca gaaactcatt ggaagatcac
     6541 ccccaaaatc atcacggcaa gaatcggccc taacgaagca ataccgacca ttccaaaact
     6601 gtcattttca tttttctttt gtttgatcat actagtcatc cctccggcaa gggccaagat
     6661 aaatggaaca gttactggac cagtagtcac tccccccgaa tcaaaagcaa tcggcataaa
     6721 ttcggaactg gtgaaaaatg aggcgatcaa aacgcctatg tagcctatag ccatcaattg
     6781 ataataggat agcttgaata cgacccgaag cagcgcaaag gctagaaata ctccagtgcc
     6841 gacgctgacg atcccaatca gcaacactct gccaatctct ccgtcagata tatcatatac
     6901 ttgttgtccc aaaacttgca cggaaggttc agcaatcgtg atcacgatcc cgatagcaaa
     6961 tcccaaactg accaaaacgg tcaaactttt ctttttgatc atatatttcc ctactagatc
     7021 tccgacttcc atcatagaat aatctgctcc aaacaaaaag agcgtcattc cgatcatcat
     7081 gattgccgca ccaaccagaa atgaagcgag gtcttctcct tctaacggtg caaaaacaaa
     7141 cgttaaaatg acaatcagga cagtcatcgg caatatagca gcaatcactt ctttaaaatt
     7201 ttttagcatg tatcctcctc ctttactctt taagtttacc ttaaaatgaa agagttttcg
     7261 agcacaaact taaaacgtta tcatttaatt tttctcaaca taaaataaca cacgtcccaa
     7321 aagtatcttt ttacttggaa aaatgacttt gaaggaacgc gcttattgtg tttttttatt
     7381 ttacagagcc gatcattcct tgaacgaatt gcttttgcaa aacaaaaaat acgatggcag
     7441 ttggtaaagt agcgatgact aatccagcca tgatcattcc atagtctggt gtataggaag
     7501 cacccatagc agataaaaca agcggaaccg tccgtttatc aggagattgc aaagctacta
     7561 agggccataa ataattgttc cagctactca tgaatgtgat gattgcagcc gcggcatagg
     7621 tatttttagc cgtcggcata tacactctaa aaaaaatact tagttctttt agaccgtcta
     7681 atcgagcggc ttctactaga tcttttggaa aagatttaac attttgtcga aagaagaaga
     7741 tcaaaaaagc agtgctaaca gatggcagga tgacaaccaa gaaactgttg attcccaaaa
     7801 ccgttccgtt caattgtgaa aacattcgat ataaagggat catcaatgcc gcaaaaggaa
     7861 ccatcatcga tagcagtaga atattgaaaa ttaggtcttt tcgtttactt tgataaatct
     7921 caaatccata tcctgccatt gacgaaatca gcaatgcaaa cacagtggtc accaaagcga
     7981 tcatcgctga attccaaagg gaacgagtaa aattcagctc attggaaaac aaattttgaa
     8041 aattgatgat caagttactg ccaatcttta tttttcccga tgtgatatcc acgggtgtat
     8101 tcgtcattcc caaaaccatc cagacaaaag ggaaaatgga aataaatgat aggatgctta
     8161 atgctgtata ctttaatact gacccaattg tcgaacgaag ttctaatgct tgttttttga
     8221 cgttggggcg ttcgattgtt tctttttcta ccatattttt catcgacttt ctcctcctac
     8281 tttcgtttgg attatcgaca atatcacaat aaaggaaaca ataacaaagg aaactgctgc
     8341 cgcatatcca aaattaggcg tgaatttata actcaaatta tagatgtatt gagatagggt
     8401 ggtcgttgca tttgctggtc ccccgccagt aatattttgt acttcatcaa aaagctgcaa
     8461 tgtcccgatc gtcgaagtaa tggaagtaaa caaaatgatt ggttttaaat ttgggatcgt
     8521 cactttgata aactgctgcc atttagaagc accgtcaata gatgctgctt cataaatctc
     8581 cgaatcaata ttttgcatgc ctgaaaggaa aaaaatcata ttgtatccag tccaacgcca
     8641 agtgatcgaa agaatgatca gaactctcgc ccaaattgga tgagtcaacc agccaatcgg
     8701 tgtgtcaatc ataccaatgc ccaacaacaa gttgtttaca aggccagatt gagaaaatag
     8761 acttttcatg atcagagaat aactgaccat cgaagtgata catggaagaa agatagcggt
     8821 tcgaaacaac cctttatatt tcaacttttt atcatttaaa aggttggaaa taaaaagtgc
     8881 tagaaacaac atgatcggta cttgtacaag taaatacagg aatgtattaa aaaaagcttt
     8941 tttaaaagtt gcatctgtca acatccgctg ataattacct aacccgttaa atgtcatatt
     9001 gacaggggga ccactttgaa aagacgtgat caaagccaaa accatcggaa taaaaaccat
     9061 gattgatatc aaaatgactg gcaagattaa aaaagcatgc ccgtttttga ataaatcttt
     9121 ctgcttcatt cttttccctc caattctatc attgattatc tacatgaaaa gacaagaaag
     9181 acaatatctg taaggcagac gtgatctttt ttgtcttttc gtttgtctga tgaaaaagcg
     9241 aagaaattca cttttttacc accgatcaat tagccaattg tgcttctact tgtttttgtg
     9301 tatctgctag taccttgtct gtctcttctc cattgatgat tcgatgaaga gcttcagcta
     9361 cgactgcttc aattgcatag gtctcatgtc cgtaattcac ttctggtatt tcagatgtcc
     9421 atgttgaaaa atcgtcaaag atcttttgac cactgtaaaa ttcagaagct tcttgataag
     9481 cttcttgttc attcgcgcta agcatcgtag atactagtcc gatttctttc gcaagagtgc
     9541 ccatcagttc ttcattcgaa gcaaacgttg cttctaggaa atctttcgct gaatcttctc
     9601 cagctactcc tttgatcaca taccagccag cgccgccaag gttagaagct tgcgcttttt
     9661 gcagattttc tggaagtgca ggtattggtg caatcttcca ttttccagat tggttttctg
     9721 ctccttggat cgttgaagaa taccaagcgc cagttgggct agaagctact gctcctgatt
     9781 gtatcgcagt tactccagca ttccagtcag aggtttgttc gactagatct tctttcaaaa
     9841 gagtggcaaa caattcaaga ccatacttta aagatgcatt gtcttggatc gtgactgtct
     9901 ccccatcttc agatgtatac cattctcctg cctgttgcat aatcatcctt actcgaccaa
     9961 ggtcagaagg attgacttca gcgattttct ttcccgtctt ttctttgaca tctcgcgcta
    10021 cttgaatata ctcgtcccac ttcagattct ccatatcctc ttctgtataa cctgcttctg
    10081 ccatcagatc cgtacgatag aagtttgctg ttacgcccga atcgaaagga acaccgtata
    10141 ttttatctcc tactttgttt accgcaaatt tatacggtgc aaaatgatct tcctttacaa
    10201 tagcagacaa attagcgaat gcatctggat aagaagtcaa atagccttgt atcctataat
    10261 cttcaatcaa gacgatattg ggcaatcctt ctgtattccc gctcgctaaa gcggtgttca
    10321 gtttctgaac gatatcatcc tgagacatcg taacaacttc tatctctgtt tcttcgttct
    10381 cataaacttt ttttgcttca ttcactgctt tgatattgaa tgtctcatcc cacgcccaga
    10441 cagtgacttt ttcttctttg tctgctgtac tactagcact tccgcatcct gttaagaaac
    10501 ctgatgctgc cgctaaacaa acgactccag caattaactt tctgatgttc atttttatcc
    10561 gctccttttc catccattag ttgtttacgt ttgctacatt catcatacca aaatttgaaa
    10621 acggtttctt tattattcag atacttcaaa aatttctcct aaaataataa aaaaatacaa
    10681 atcaactatg acaaaaggaa taatcttagc atctagacca aagatcgaaa tggtgaggtt
    10741 tctttaaaat aaaaatatcc ttgcattttc tc
//
LOCUS       DAFTHM010000088        10507 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFTHM010000088 DAFTHM010000000
VERSION     DAFTHM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.088"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..482
                     /locus_tag="L7C88_002201"
     CDS             <1..482
                     /locus_tag="L7C88_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBP9559008.1"
                     /translation="LGLSMGGIFAVRALEEESVIGGGFFCSPLSPVKTNVPENFEKYV
                     RQVLKTAGKSEKEINEKAVAYRSLAEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKD
                     EMIDPNGVFETARKLSRQRVTLRWYPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            485..2842
                     /gene="rnr"
                     /locus_tag="L7C88_002202"
     CDS             485..2842
                     /gene="rnr"
                     /locus_tag="L7C88_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBP9559009.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWATELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            2864..3328
                     /gene="smpB"
                     /locus_tag="L7C88_002203"
     CDS             2864..3328
                     /gene="smpB"
                     /locus_tag="L7C88_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBP9559010.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            3630..4349
                     /gene="atpB"
                     /locus_tag="L7C88_002204"
     CDS             3630..4349
                     /gene="atpB"
                     /locus_tag="L7C88_002204"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBP9559011.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            4402..4617
                     /gene="atpE"
                     /locus_tag="L7C88_002205"
     CDS             4402..4617
                     /gene="atpE"
                     /locus_tag="L7C88_002205"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBP9559012.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            4708..5232
                     /gene="atpF"
                     /locus_tag="L7C88_002206"
     CDS             4708..5232
                     /gene="atpF"
                     /locus_tag="L7C88_002206"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBP9559013.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            5219..5761
                     /locus_tag="L7C88_002207"
     CDS             5219..5761
                     /locus_tag="L7C88_002207"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBP9559014.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNKAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            5784..7340
                     /locus_tag="L7C88_002208"
     CDS             5784..7340
                     /locus_tag="L7C88_002208"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBP9559015.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            7354..8256
                     /locus_tag="L7C88_002209"
     CDS             7354..8256
                     /locus_tag="L7C88_002209"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBP9559016.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            8279..9685
                     /gene="atpD"
                     /locus_tag="L7C88_002210"
     CDS             8279..9685
                     /gene="atpD"
                     /locus_tag="L7C88_002210"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBP9559017.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            9699..10121
                     /locus_tag="L7C88_002211"
     CDS             9699..10121
                     /locus_tag="L7C88_002211"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBP9559018.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         3500 a         1857 c         2313 g         2837 t
ORIGIN      
        1 tattaggatt atcaatgggc ggcatctttg ctgtacgagc actagaagaa gaatcagtga
       61 ttggcggcgg ttttttctgt tcgcctttgt ctcctgtaaa aacaaacgtg cctgaaaact
      121 ttgaaaaata cgtacgtcaa gtgctgaaga cagcaggtaa atcagagaaa gaaatcaatg
      181 aaaaagcagt tgcttaccgc tcgttagctg aacaacaatt aatggatata caagatcagg
      241 cagcaatcgt agaaagtagg ttgtcagata tccaacagcc gatattttta gctcaagctg
      301 ggaaagatga aatgatcgac cctaatggcg tatttgaaac tgcacgcaag ttgagccgtc
      361 agcgagtgac acttcgatgg tatcctgaaa gtggtcatgt gattacagtt ggtacagcaa
      421 gacgcgaatt agaaaaagac gtcttggaat ttttagaaaa attaccttgg aatgaggaat
      481 aaatatgaca aaagaaacga taaaagagaa aattctcttt ttcatggaaa gcagtcgcaa
      541 acgcagtttt tctatggaag aaatcgctga aggtttaggg ttccaaaaaa gcgatgattt
      601 taaattacta gtacaaacga ttgctcaaat ggaaagagaa cagagtatag ttttcaataa
      661 aaaaggaaaa gtgaaacttc ctttaaaacc aatcttgatc gaaggaacat ttcgagcaaa
      721 tgaacgagga tttggatttg taacgattga tcccgaagaa gatgacatct atatcccaaa
      781 agaagcgact ggttttgcaa tggatggaga caccgtagca atcgatatca tgaagcgagc
      841 aaatacagat atggatcgcg gagcagaggg gaaagtagtc gagattcgag accgggcgac
      901 tactcagtta gcaggggaat tcgttgctta ttcagaagaa gaaatacaag aaacggatct
      961 ttacggcgtt gttatcccga aagatagaaa gctcaaccaa tttaaagtat atgcagcagc
     1021 agagggagtt cgtccagttg acggaagtat tgtgctgatc gaactgaccc attaccctga
     1081 aaaagggtat gcgactagtt tagaagggat aatcaagcaa gtgattggtc ataagaatga
     1141 ccctggcatg gatatcctct caattgtcgt ggctaatggt atccctacga aatttcctga
     1201 tgatgtattg tctgaagcag atgaagttcc agatcaaatc agcgaaaagg atataactgg
     1261 acgtagagat ttaagaaatc agctcattgt tacgattgat ggagaagatg caaaagatct
     1321 agatgatgca gttacggtta aaaaattaga taacggtaat tattttcttg gagtacacat
     1381 tgcagatgtt tcttactatg tgacacaagg cagtcaattg gacagagaag catatgaaag
     1441 agggacaagt gtatatttga ctgatcgagt gattccgatg atcccgcaac gtttatcgaa
     1501 tggtatctgt tcactgaatc cccatgttcc aaggctgacc atgagttgcg aaatggagat
     1561 tgatccaaat ggacaagtag tctctcatga tattttccca agtgtgatcc aaacaacaga
     1621 acggatgacc tacacagctg tcaatcaaat cttagaagat caagacgaag aaacgatgca
     1681 acgctatgct cagctcgtac ctatgttcca agaaatgggt gaattgcatc gaatccttga
     1741 aacgatgcga atcaaacgtg gcgcgatttc ttttgaggat cgcgaagcaa aaatccttgt
     1801 tgatgctgaa ggacacccaa atgatatcca gctaagaagc agaggaattg gtgaacgctt
     1861 gatcgaatct ttcatgcttg cggccaatga aacggtagct gaacattata ataaattaaa
     1921 tctgccgttt atttaccgaa tccatgaaca gccaaaagaa gaaaaaatgc agcgcttctt
     1981 tgattttgct tcagctttgg gcattctggt ccgaggaacg aaaggaacga tcacaccaaa
     2041 agatttacag catgtgatcg aaggagtaga agacaaacca gaagctgcag ttatcaatac
     2101 tatgttgcta agaagcatgc aacaagcacg ctattcagaa gacaattttg ggcattatgg
     2161 cttagcggca gattactaca cacactttac atctcctatt cgacgctatc ccgatctaat
     2221 cgtccatcgt ctgatccgtt cttacagtga agataaaagt gaaagcaatc aaagttcgtg
     2281 ggctacggaa cttcctgaaa ttgcagatca tagttctaag atggaacgtc gtgcagtaga
     2341 aacagaacgt gaagtagatt ccatgaagaa agcagaattc atgatggaca aagtggggga
     2401 agaattcgat gggatcatca gctctgttgt gaaattcggc ctgtttatcg aactgccgaa
     2461 tacagtagag ggattgatcc atatcaatga attgaaacag gactacttcc attttgttga
     2521 aaatcattta gctcttgtag gtgaaagaac tggtctgact tttaaaatcg gacagaaagt
     2581 gcgagtaaaa gtagtcaaag ctgatccaga tgaacgagca gtagattttg aacttgtttc
     2641 cgcagaagag gttacagcgt tggaacggcc aaaaacacga aatggaaaat caggaaaacg
     2701 cgaaggaaaa caagcaggaa aacgcccaga aagaaatggc aagaagaaca aacgatatag
     2761 cgatagtaag caaacgttcg gtaagaaaaa agggaagaag ccattttaca aaggtgttaa
     2821 aaagaagaaa aagaaaaaat aaaatgagtt ggaggaaaca gctatgccaa aaggcgaggg
     2881 aaaattaatt gcacaaaaca agaaagctcg ccatgattat tcgatcatcg acacgatgga
     2941 agcagggatg gtcttgcaag gaaccgagat caagtcgata cgaaacagcc ggatcaatct
     3001 aaaagatgga tttattcgcg tccgcaacgg agaagctttc ttgcataatg ttcatatcag
     3061 tccttatgaa caaggaaata tttttaatca tgatccgttg cgcacgagaa agttattatt
     3121 acacaaaaaa caaatcatcc ggcttgaaaa tgaattgaaa aatactggaa tcactgttgt
     3181 tcctttaaaa gtctatattc gtaacggcta tgccaaggta ttgattggtc tggcgaaagg
     3241 gaaaaaatct tatgataaac gggaagattt gaaacgaaaa gatatcgatc gacaaattga
     3301 tcgaacatta aaaaatttct ctagataatt tcattatcct ttttcgcata ttcggtgctt
     3361 ttgcttttac ttaatgataa aatttgttag catttaatct gataaaacat gattatcata
     3421 ggttttttct tagatcagga gcaccgtgta taaagaaaaa ttcgcttcgt ttttgactga
     3481 aataaaaaag tgtctaattt tcatgaaaat gttttgaatt ttctgtttca tggtggtatg
     3541 ataccgtgtg gttagaaacc gattggaaaa aaccagatac gcacatgaat tgattttatg
     3601 tgaatttcgg ggaaaagagg tgaaatggat tggatgaacg ctcgctaacg ttccacattg
     3661 gaccaatttg gtttgatggt acagtttgta taatggtgtt actgacctgt ttgattgttt
     3721 tcttcttagc ttactttttt acaagaaatc ttaagttgaa accaacaggc aaacaaaatg
     3781 cgatagaatg ggtcattgat tttagtcgag gaatcgtaac agataatctg cctagaaaag
     3841 aattgagcaa tttccatttg ttggcattta cattgttttt atttgttttt gttgcaaaca
     3901 acatcggttt agtaacaaaa atcgttttac ctaacgaaac aacactttgg aaaagcccga
     3961 cagcagaccc gtttgttact ttaactttgg catttataat gatcttactt actcacttat
     4021 ttggggtgaa aaagttaggc ttcaaaggat atttcgtaaa ttcgttcttg aaaccatata
     4081 gttttatgtt tccgatgaaa ctgattgaag aatttacaaa cttattaaca cttgctttac
     4141 gtctttatgg gaatatttat gcgggggaag ttttgctaac cttgattgca aaaatggtaa
     4201 taagcttagg ctggttctca ttgccgttag caattccatt agagatggtc tggatcgcat
     4261 tctccttgtt tatcggaagc atccaagcat ttgtcttcgt tactttatct atggtttata
     4321 tgagccataa gattgaagtg gaagaataat attcgtttta aaaacaaact actatttatc
     4381 taatttagga ggaaaacaat tatgaattat atcgcagcag caatcgcaat catgggagca
     4441 gcaatcggag ccggttatgg taacggtcaa gttatctcta aaacaatcga atcaatggct
     4501 cgccaacctg aaatgtctgg tcaattccgt acaacaatgt ttatcggggt agctctagtc
     4561 gaagctgttc ctatcttagg ggtagttgtc gccttgattc tagtttttgg tgtttaattg
     4621 aatcagtatt aaggcagaaa caatttggtt tgttactgct tttttacatg aaaactagaa
     4681 gtacttcaaa gaaaggaagg ctcgcctatg ctgaatcaat tggcaattgc agaagttggc
     4741 aatgcgatgt taggaaatgt catcgttgtc agcggctcat ttttgatact actggctctc
     4801 ttgaagcatt ttgcttgggg accaatcagc gatattttga aaaaacgtga agacaagatc
     4861 gccaatgatt tggattctgc agaacaatct cgcatcaact cagcgaaaat ggaacaagaa
     4921 cgcgaacaac aattgttagc ctctcgttct gatgcagctg atatcatcaa aaatgcgaaa
     4981 gaaagtggag aattaagccg ccaaaatatt ttgaaggatg ctcaagaaga agcagctcgt
     5041 ctaaaaagta aagcccaagc tgatatcact gtagaacgtg attcagcgct gaactctgta
     5101 aaagacgatg ttgcagaact atctcttcaa atcgcggaaa aaatcttgaa caaagaatta
     5161 tctccagaaa tgcacgaatc attaatcaat caatatatcg aaggtctagg ttcttcaaat
     5221 gaaactagat aaatatacag taggaagacg ttacgggaaa gctttatttg aactggcgat
     5281 cgattcaaat aaagcagaag aaatttatca agatctcgta agcttacgtc aaatctatga
     5341 acaagtacct ggattaggta atatgttaag tgatgttcgt ctagaacctc atgaaaaacg
     5401 agaaatcatg gacaagcttg ttagtggcta tgatggaatc gttaaaaact ttttagaagt
     5461 tgtttatgcg tataaccgaa tggatgatct tttgttcatg atcgaagaat atgaacgtcg
     5521 atatgatgaa catcaaggtt tgctgttggg aagtgtcaca acagcagttc cactttcaga
     5581 cgaacaacga atacaattag aaaagaatgt tgcaaaaaca atgaactatc aatcagtcga
     5641 attaaaacaa atcgttgatt cttctattat tggtggcgcg attgttgaag ctaaccatcg
     5701 agtaatcgac ggaagcattc gcacgcaatt agaaaatatg cgtaatcaat taaatagata
     5761 gtacaaagag gtaggtgaat cgaatggcca tcaaagcaga agaaattagt gccttgatta
     5821 aagaacaaat tgaaaattat caaaacgtgc tttcagtcga agaaatcggt accgtaactt
     5881 atgtaggtga cgggatcgct cgtgcacatg gtttagaaaa cgcgatgagt ggtgagttgc
     5941 ttgaattttc aaatggctca tacggaatgg cgcaaaactt agaatcaaat gatgtaggta
     6001 tcattatcct tggcgatttc gagtccattc gtgaaggaga taaagtaaaa cgaacaggaa
     6061 agatcatgga agttccagtt ggagaggcct tgattggacg ggtagttaat ccgctaggtc
     6121 agccaattga cggactaggt gaaatcgtta ctgacaaagc tcgtccagta gaagcaatgg
     6181 caccaggcgt tatgcaacgt aaatctgtta acgaaccaat gcaaacaggt ctaaaagcaa
     6241 tcgacgctct tgtaccaatc ggacgcggcc aacgtgaatt agttatcggt gaccgtaaaa
     6301 cagggaaaac ttccattgcg atcgatacga tcatcaacca aaaaggtcaa gatatgatct
     6361 gtatctatgt agcaatcgga caaaaagatt ctacagttcg tacacaagtt gaaacattga
     6421 aaaaatatgg cgcaatggat tacacaatcg ttgtgaatgc cggtgcgtct caaccagcgc
     6481 cgttgcttta tatcgcacca tatgctggta ctgcaatggg tgaagagttc atgtacaacg
     6541 ggaaacatgt cttgatcatt tttgatgatc tttcaaaaca agctgttgct tatcgtgaac
     6601 tttccttgct gcttcgccgt ccaccaggtc gtgaagctta tccaggggat gttttctact
     6661 tacactcacg cttattggaa cgtgcagcaa aattaagtga tgatttaggt ggcggttcaa
     6721 tgactgcctt accatttgtt gaaacacaag ctggagatat ctctgcttat atcccaacaa
     6781 acgttatttc gatcactgat ggacaaatct tcttagaaag cgacttgttc tacgcaggta
     6841 ctcgtccagc ggttgatgcc ggactatctg tatctcgtgt agggggttct gcgcaaatca
     6901 aagcaatgaa aaaagttgct gggactttac gtctagactt agcaagttac cgtgaattag
     6961 aagcatttac acaattcggt tctgacttgg atgcagcaac acaagcaaaa ctaaatcgtg
     7021 gacgccgtac agtagaaatc ttgaaacaaa aattgcatgc accgctagct gttgaaaaac
     7081 aagtagtgat tttgtatgct ttgacacatg gattcttaga tagtatccct gtagacagta
     7141 ttttagactt cgaacatgaa ttattcgaat atctggatac caatcattca gatatctttg
     7201 aaacaatccg tacaacaaaa gatcttccag aagaagaagc gttgaacagt gcgattcagg
     7261 aatataaaga catgttctta gctacaaaag gaaataattc ctctacagaa gataaattga
     7321 aatccattca aaatgcatag tgaggtgaga tgaatgggtg cttcattaaa tgaaatcaag
     7381 acacgtatcg cttcaacgaa aaaaacgagc caaatcacgc gggcaatgca gatggtgtct
     7441 gcttctaagt tgacaaaatc tgaagcttct tcacagaagt ttcaggttta tgcaacaaaa
     7501 gtaagagaaa tcgttacgca tttgactgct actcagttaa atgatattgc ctcagaaaat
     7561 cctagagggg atatcaatta caacagcatg ttgctcagcc gtcctgttaa gaaaacgggt
     7621 tatatcgtca tcactgcaga tggcggttta gtcggtggat ataacagctc gatattgaaa
     7681 caaacgatgt ctattttaga agaagaccac caatcacccg atgattacgt gatgatcgca
     7741 attggcggaa ctggtgcaga cttctttaaa gcacgcggta tcaatctagc atatgagctg
     7801 cgcaatctat ctgatcagcc aagctttgat gaagtccgca aaatcgtaaa tatggcaaca
     7861 actatgtacc aaaacgaagt attcgatgaa ttatacgtat gttataacca tcatatcaat
     7921 tcgctaacta gtcagtttcg tgtagaaaaa atgctgccaa tctcagactt agatccagaa
     7981 gaagcaacta ctttcgaaca agaatatatt tttgaacctt caaaagaaga aatcttgtct
     8041 cagttattgc ctcagtatgc tgaaagtttg atctacggtg cgatcgttga cgccaaaaca
     8101 gcagaacatg ctgctggtat gacagcaatg aaaacagcaa ctgataatgc tgctaatatc
     8161 attgatgagc tgacggtttc ttacaaccgt gcaagacaag gggctattac ccaagaaatt
     8221 accgaaattg ttgccggagc ttcggcacta gaatagtatt gagattggag gaaaaaagat
     8281 gagttcaggc aagattgttc aagtaatcgg tcccgttgtc gacgtggaat tttctttaga
     8341 ccaatcctta ccagatatca acaacgcatt agttgtttat aaaaatgacg aaaataaatc
     8401 aaaagttgtt cttgaagcag cgttagaatt aggggacgga gtgatccgga ccattgcgat
     8461 ggaatcaaca gatggtttac aaagaggaat ggaagtcatt gatacaggca aagcaatctc
     8521 tgttcctgta ggtaaagaaa cattaggtcg cgtattcaac gtactaggag atacgatcga
     8581 tttagaaaca cctttcccag aagatgcgga aagaagcgaa attcataaaa aagcaccagc
     8641 ctttgacgaa ttaagtacaa gtacagaaat tttggaaaca gggatcaaag ttatcgattt
     8701 gcttgcccca tatttaaaag gtgggaaagt cggactattc ggtggtgccg gtgttggtaa
     8761 aaccgtactg atccaagaac tgatccataa tatcgcccaa gaacatggtg gtatttctgt
     8821 atttaccggt gtaggtgaac gtactcgtga aggtaatgac ttgtattatg aaatgaaaga
     8881 ttcaggagtt atcgaaaaaa cagccatggt gttcggacaa atgaacgaac caccaggtgc
     8941 acgtatgcgt gttgctttga ctggtttgac gattgcggaa tatttccgtg atgtagaagg
     9001 tcaagatgta ctgttgttta tcgacaacat tttccgtttc actcaagctg gatctgaagt
     9061 atcagccttg ttaggacgga tgccttctgc ggttggttat caaccaacat tggcaacaga
     9121 aatgggtcaa ttgcaagaac gtatcacatc tacgaaaaaa ggttcgatca catcgatcca
     9181 agcaatctat gtgccagccg atgactacac tgacccggcg ccggcaacag cattcgccca
     9241 tttggatgcg acaaccaact tggaacgtaa attaacagaa caagggattt atccagcggt
     9301 agatccattg gcttcttctt caagtgcttt agcacctgaa atcgtgggag aagaacatta
     9361 taaagtagca acagaagtcc aacacgtatt gcaacgatat cgtgaattac aagatatcat
     9421 tgctatctta ggtatggatg aattatccga tcaagaaaaa gtgttagttt ctcgtgcccg
     9481 cagagtccaa ttcttcttgt cacaaaactt taacgtggct gaacaattta ctggtcttcc
     9541 aggttcatat gtccctgtag aagaaacagt gaaaggattc cgcgaaatct tggaaggcaa
     9601 atacgatgat cttcctgaag aagctttccg aagtgttggc cgaatcgaag acgtcgtaga
     9661 aaaagcgaaa acactaggct actagaaagg ggtgccccat ggatcaatat ttaacagtaa
     9721 atgtggtaac tcctgccggt ttggtctatg atcaccatgc agctatcgtc gttgcacgta
     9781 cgacagctgg tgagcttggg attttgccta aacatgcacc aatcatcgtt ccattgacga
     9841 ttgatgaagt tcgtgtaaaa cgaacagatt cagataccca cgtcgattgg atcgctgtta
     9901 atggcggaat catggaagtt cgtgataatg ttgtttcaat cgttgctgat agtgcggaac
     9961 gtgaacgtga tatcgatgta tctcgtgcgg aacgtgcaaa acaacgcgca gaacgccaaa
    10021 tcgaagaagc aaaagcaaaa caagatacga acgaattgaa acgggcaact gttgcgttgc
    10081 accgagcaat caatcgtatc aaagtatcta agcactcata aaatgagatg cggatgttta
    10141 tccgtgttta agaacagtaa aaagaggtta tgacagaagt ggtcagcttc aagacataag
    10201 aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ctcagcttat ttttcgaaga
    10261 agctacttct ggaacaccgt atatcggagg ttgtgaaatc agcgttttgt cctgagtatt
    10321 agagaaacaa atggaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaggg
    10381 tcagatgatt gaacaccgtt tatttggaat aagggactgc gacaagactt ttgggctctt
    10441 tgtcaataag gactgatgag ttgtgcaaaa tcaaatctga gtcagaatga accacattct
    10501 ggctcag
//
LOCUS       DAFTHM010000089        10458 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFTHM010000089 DAFTHM010000000
VERSION     DAFTHM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.089"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..1171
                     /locus_tag="L7C88_002212"
     CDS             <1..1171
                     /locus_tag="L7C88_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBP9559019.1"
                     /translation="LMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKP
                     STVIDFDIPKKYGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTN
                     PMAMLTMGVLKATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAF
                     LLEITKNGEDFYPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIK
                     SKYPELIDELGIPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSIT
                     TGTPSVIAGNVLNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNIN
                     VQELTVEAALTLDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            1319..2578
                     /locus_tag="L7C88_002213"
     CDS             1319..2578
                     /locus_tag="L7C88_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBP9559020.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            2588..3460
                     /locus_tag="L7C88_002214"
     CDS             2588..3460
                     /locus_tag="L7C88_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9559021.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            3472..4302
                     /locus_tag="L7C88_002215"
     CDS             3472..4302
                     /locus_tag="L7C88_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9559022.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            4342..6525
                     /locus_tag="L7C88_002216"
     CDS             4342..6525
                     /locus_tag="L7C88_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBP9559023.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            6586..7806
                     /locus_tag="L7C88_002217"
     CDS             6586..7806
                     /locus_tag="L7C88_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HBP9559024.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            7803..9263
                     /gene="gtfA"
                     /locus_tag="L7C88_002218"
     CDS             7803..9263
                     /gene="gtfA"
                     /locus_tag="L7C88_002218"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HBP9559025.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            9340..10446
                     /locus_tag="L7C88_002219"
                     /pseudo
     CDS             9340..10446
                     /locus_tag="L7C88_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
BASE COUNT         3551 a         1633 c         2055 g         3219 t
ORIGIN      
        1 tttaatgctt aaaaatatta ataaaaattc gaatgaaaat cgtgctgata ttgtttctta
       61 ttatgatcgc aaagaagcgt taagagaggc tgattttgtt atcaatgcta ttcaagtggg
      121 tggttataaa ccttcaacag tgattgattt tgatattcct aaaaaatatg ggttgcgaca
      181 aactattggt gacaccatgg ggattggtgg gatttttaga accctacgga cactaccagt
      241 aatgttagac tttgctaaag aaatggaaga agtttgtcca aatgcttggt tattgaacta
      301 tacaaatccg atggcgatgt taaccatggg tgttttaaaa gcgacgagta ttaagactgt
      361 tggtttatgt catagcgttc aagtatgcgt accagaattg tttgagcatt taggaatagc
      421 cgatcaatat gacttaaatg actttcaatg gaaaattgca ggcattaatc atatggcatt
      481 cttgttggaa attacaaaaa atggggaaga tttctatcca acaattcgtc agttagctgc
      541 agaaaaacca aatccacatc cagattctgt acgttttgaa ttgttgaaac gttttggtta
      601 ctatattaca gaatcaagtg aacacaatgc agaataccat ccatacttta ttaaatcaaa
      661 atacccagaa ttgattgacg aattagggat tccgttggat gaatacttac gtcgttgtga
      721 acaacaaatt aatgattggg aaagcatgcg agaggacatt gtaaataatg gggagttaac
      781 acatacgaga agccgtgaat atgcttcata tatcatggat tctattacga caggaactcc
      841 gtcagtgatt gcaggaaatg tcttaaataa aggcttaatc acaaacttac cgacagatgt
      901 ttgtgtggaa gtaccttgtt tagtcgataa aaatggcgtg caaccaacct atgtcggtga
      961 attgccaaca caattagctg ctttaaatcg gacgaatatc aatgttcaag aactgacagt
     1021 agaagccgct ttaacactag ataaatcaaa aatttatcaa gcagcgtatt tagatccaca
     1081 tctatcatct gaattgtctt taacagatat caaaaattta gtggatgatt taatcgaagc
     1141 acatggggac tatttacctg aatataatta aaaagaagct gaaagagtaa ggaattttca
     1201 attccttact cttttcttag ttaaatttag taaaaatatt gacaaaacac ttagtaaaca
     1261 gttacattag tgttaacaaa aagaaaacgc attcaaattg tataaggagg agcataaaat
     1321 gaagtggtct aaaaaaatta ttttagcttg tatagcacta ggagcaacga tctctttgac
     1381 tgcttgtgga aaaaatcagg aagatgcaag cggtaaggta gaaatagagt tttttaatca
     1441 aaaaaaagaa atgactcaaa cgattcagga gattgctaaa gattttgaag caaaaaaccc
     1501 tgatattcat gtaaaagttg tggatgtacc gaatgctggt gaagtaatta aaacacgtat
     1561 gcttgcaggc gatgtaccag atgtcattaa tctttatcct caaagtatag aattgaaaga
     1621 atgggcgaaa gctggttatt tagaggactt aaccgaagaa ccgtatttag agaatatcaa
     1681 aaatggatat gcacaacgtt ttgctattga ggatcgtgta tatagcatac cattaaccgc
     1741 taatgtctat ggtttttact ataacaaaac tgcttttgag gaaatgggga ttcaagcacc
     1801 agaaacttgg gcagaatttg aaaaaatagt agctgagatt aaagatcaaa acaaagtacc
     1861 gtttgcgatt gcaggagcag aaggctggac tttaaatggt tatcaccaac tagctatagc
     1921 gactgctgct ggtggtgaag aggaagcgaa caatgtttgg cgtttctcag aagttaatgg
     1981 aattaatgct gaaagcaaag aaatgcaaaa agattttaat cgattagatt tgttaagaga
     2041 accaaaagct ttgcaaaaca actggcaagg tgccggttat aacgatacag tagttacttt
     2101 tacaaaaggt gatgcgttga ttatgccgaa tggttcatgg gcaatgccga tgattcattc
     2161 acaaaatcca gattttgaag taggaacttt tccttttcca gcagatgaag caggtcaaag
     2221 tctaacgatt ggcgcaggag acctagcctt atcagtttct gcaacttctc aacataaaga
     2281 agaagccaaa cgttttgtag aatatatgac aacacctgaa gcgatgcaga aatattatga
     2341 tgtagatggt gcaccgtgtg ctgttgaggg cgttatcgag aatactcagg attcaccatt
     2401 aagtggttta actgaacttg cttttactga tcgtcattta gtttggttag ccaaagattg
     2461 gaatagtgaa aatgattttt ataccttaac aacaaattat ttacacaatg gcaatcaaaa
     2521 agccatgatt aacgcattaa atgctttctt taatccaatg aaagctgacg gaaggtagga
     2581 aaataaaatg aaaataaaag aaattttaaa tcgttactgg gcaatcattt ttgtagcaat
     2641 tccaattatt ttgcagatga tttttttcta ctttccaatg gttcaaggtg ctttttacag
     2701 tttaactaat tggactggtc tgacttataa ttttgatttt gtgggtttga acaattataa
     2761 gattcttttt tctgatccga agtttatcaa atcgattggc ttcactttaa ttgtgacgct
     2821 ttgcatgatt gctggacaaa ttggttttgg tattttgatt gcgcgggcgt tgaacgcaaa
     2881 tattaaaggg aaaacattct ttagagcatg gttctttttt ccagcggtct tatcgggcgt
     2941 ggttgtttct ttagtattta aacaaatttt taactatggt ttaccaaaaa ttggtagtat
     3001 gttaggcatt gaatttttac aaaccagtct tttaggaaca acatggggag cgatttttgc
     3061 agtaattttt gttttacttt ggcaaggaat tgccatgcca gtcatcattt tcttagcggg
     3121 ttttcaaagt attccacaag aaattattga agctgctaga atggatgggg cgaatgataa
     3181 gcaaattttt tggaatattg aaatcaccta cttattacca agtatttcaa tggtatttat
     3241 tatggcatta aaaggtggct taacagcatt tgatcaaatt tttgctttaa ctggtggtgg
     3301 accaagcgat gccacaacat ctttggggtt acttgtttat aattatgctt ttaaaaacaa
     3361 tcagtttggt tatgcgaatg ctattgcttt agtcttattt atcttaattg ggattgtttc
     3421 actggcacaa ttaaaattat cgaaaaaatt tgaaatctag gaggtttccc aatgaaaaca
     3481 tcaaaagaaa aaaatatttc taaatacttg cttttattat tagggggctt catgatttta
     3541 gttcccttag tttcaacgct attcggttca tttaaaacaa cacccgatat tatgaataat
     3601 ttctttcgtt ttcctaatcc agcgactttg gaaaatttcc gaagattgtt agcggatgga
     3661 attggtcatt acttttggaa ttcggcaatc atcacaatca ttgcagtagt tgctgtgaca
     3721 gcaattattc ctatggctgc ttattcacta gcaagaaaaa tgactcgtgg gaaagcatac
     3781 ggattgatgt atttattttt aattttagga atttttgttc ctttccaagt aattatgatt
     3841 ccgattaccg ttatgatgag taaaattggt ttagcaaata tgtggggatt aatcttactc
     3901 tatctcactt atgccgtacc acagacacta tttttatatg ttggttttat taaactaaat
     3961 gtgcctatca gtctggatga ggctgctgaa attgatgggg ctagtcactt tacaacttat
     4021 ttcaaaattg ttttcccaat gttaaaacca atgcatgcga cgactattat tcttaatgct
     4081 ctatggtttt ggaatgattt catgctacca ttattaattt taaatcgtga ttctaatatg
     4141 tggacactac cattgtttca atataattat acgggacaat attttaacga ctatggtcca
     4201 agttttgctt cctatacagt aggaattgtc acgattacac tagtttatct tgctttccaa
     4261 agaagtatta tagctggaat gagcaatgga gcagtgaaat aaccaataaa ttattctcat
     4321 tataaaggag ttcataaact tatgattata tttgacaatc acacacaaac atttcattta
     4381 caaaataaaa aaattagcta tctattagga atcgaagaaa ataattattt aacgcatctt
     4441 tattttggaa aaaagattac gcactattct ggtgggtatc gctacccccg aacagatcgt
     4501 tccttctcac ccaacaatgc aaatgcgcaa gatcgtttat tatctttaga cacattacca
     4561 ttagaatttc caggatatgg acatggtgat tttagagaac cggcgcataa tattaaatta
     4621 ggaaacggta gtcgtgtaaa tgattttcgt tatgatagct acgaaattca aaaaggaaag
     4681 cccagcttag cgggattgcc agccttatat acggaagatg atgatgaagc tgaaacgctg
     4741 attattcaat tgaaagacgc gattagtgga ttgactttac agttgttcta cacaatttat
     4801 caaaatcaca gtgtaattat tcgttctacg caattagtaa ataatagtga tgaaacagtg
     4861 gagattaacc gcttagctag tcaatcaatt gattttccaa atcgtccact cgagttaatt
     4921 catttaaatg gtacctgggc aagagaacgt caaatgacta gagaaaaaat tcatacaggg
     4981 ataaaagtat tagatagtaa acgcggatca agcagccatc aacaaaatcc gtttgttgct
     5041 ttagtagatg ccaaaacaga tgaatttcaa ggagaggcat atggatttaa tttagtttat
     5101 agcggtaatc acgaaacggt gattcaaaaa gatccatttg accaaacacg ggtcattatg
     5161 ggaattaatt catttaattt tggttggcaa ctaaaaactg gcgactcatt tcaaacgcca
     5221 gaagtcgtga tggtttatag taatgaaggt ctgaatacgt tatcacagac gtatcatgaa
     5281 ttgtataatc accgtttaat tcgtggaaac tatcgtttaa aagaacgtcc cacgttaatc
     5341 aacaactggg aagcaacgta ttttgatttt aacgaagaaa aaatcatgaa tattgtcgat
     5401 gatgcgaaga acttgggcat tgaaatgttt gttttagatg atggttggtt tggcggtcgt
     5461 gaaaatgact tcacttcatt aggtgattgg gttgaaacag aaggcaaact tgcttgtggt
     5521 ttggaaaatt tagccaagca agtgcatgat aacgggatga aatttgggat ttggtttgaa
     5581 ccggaaatga tttctgaaga tagtgaacta tttcgagcac atccagattg ggcattgggt
     5641 attccaggtc gtgaccgctc aattagtcga aatcaatatg ttcttgattt ttcaagacaa
     5701 gatgttcgtg ataatatcta tcaacaaatg acggcgattt ttgatcgtgt accgattgat
     5761 tatgtgaagt gggatatgaa tcgaaatatg acagaagtct attctgtctt gttggactca
     5821 acgatgcaag gtgaagtggc tcatcgttat atgttagggt tatatgaatt tttagaaaag
     5881 ttaacaacga attatccaac tattttattt gaaagttgtt cgggtggagg cggtcgtttt
     5941 gatgcaggtt tcttgtatta catgccacaa acttggacga gcgacaatac cgatgccgtg
     6001 gctcgtctga aaattcaata tggaaccagc ttagtgtatc caatttcaag tatgggtgcg
     6061 catgtttcag cagtcccaaa tcatcaaaca ggaagagaaa cgagtttaac tattcgtggc
     6121 aatgctgcga tggctggtgt ttttggttat gagctagatc taacgcaatt aacttctgaa
     6181 gaaaaagcag aaattaaaga acaagttgcc ttttataaaa agcatcgcca acttttgcaa
     6241 tatggaactt tttatcgctt ggaaagtccg tttgaaggca atgatactgc atggatgttt
     6301 gtctcaaaag accaaacaga agccatggtc ttttatttcc gagtattagc agaagctgcg
     6361 catccattag tcacattgaa attagcagga ttagcagaag aagcaactta tcaaatggaa
     6421 gatgtaacat ttgctggcga tgaattgatg aatctcggtt tttatattga ctcagaacta
     6481 catggtgatt atgcgacaca acgcttttat ttgaaacaga tatagtagct tgaatttaca
     6541 atataagtgc aacaccaaaa gagactcatt ccaaacgaag aaaatatgtt ttatttacac
     6601 gcatttacta aaaagcagcc tgatttgaat tgggaaaatg aagaagtacg tgaagaaatc
     6661 tatgcaatga ttaactattg gttagataaa ggactaggcg gatttagaat cgatgcgata
     6721 ttaaacatca aaaaaaaact agagtatggc atctttgaat ctgatggaga agatgggtta
     6781 gccttcattg ggccctggat tcttaatcag tcgggcattg aagtgtggtt aaaagaaatg
     6841 agagagcgga catttaaacc acataatagt atgacggtag cagaagccga tgttcctaat
     6901 gaacgtttag atgaatatat tggtgaagat ggctattatt cgatggtttt tgattttagt
     6961 tatacggata ttgatgtacc tgaaactggt gaatggttta aagatagcca atggacatgg
     7021 acggatatgc gtaccaatat ttttacgaat caattagtta cgcaagataa aggttggggc
     7081 gccttatatt tagaaaacca cgatcaacca cgttcaatta ataaatatat tccagaagaa
     7141 tggatcaatg attatagtaa aaaaatgttg gcgacgcttt ttatgttact aagaggtacc
     7201 ccttttattt atcaaggaca agaactagga atgaccaaca tagaaatggc atcattagaa
     7261 gattttgatg atgtagctac gcattctcag tataaacggg cattagaata tggattggca
     7321 ccagagcaag cattgaaagc tgtcaataaa cgaagtcggg ataattctcg cacacctatg
     7381 caatggaata cgcaaaaaaa tgccagattc tcaacttctg ataatgtatg gttaaaagta
     7441 aatcctaatt atccagaact caatgcagaa gctcagttaa ccaatcaaca gtcggtattc
     7501 aattattatc atcaattaat taaattaaga aaaaatagtg tatacaaaga cgtgctaatc
     7561 tacggacaat ttctaccagt gaaagataaa aatgaacata ttttgcttta tgaacgccaa
     7621 ttagaagata aaatcgtatt agttatctta aacgttacag caacagaaca agaatattat
     7681 gtagatgaac agtaccaaca agtattaatc aataattatg aagatgtttt attagatcaa
     7741 agtcgaaaat tgcgtttacg accgtttgaa agtattgtat tagctaatta tggaggacaa
     7801 ttatgaaaat taaaaacgaa gcaatgctca tcacctatgc agatagttta ggaaaaaaca
     7861 tgggcgaatt aaaacaagtc ttagacaaac atttacaagg tgttattggt ggtgtacatc
     7921 tgttgccttt ttttccatcg acaggtgatc gaggctttgc gccgagtgat tatacgacag
     7981 ttgatccagc tcttggaaca tgggaagatg tggaagcatt aggtgaagat tattatttga
     8041 tgtttgattt tatgattaat cacatttctc gtgaatcaaa atttttccaa gatttcaaaa
     8101 aaaaccatga gcagtcacca tacaaagaaa tgtttatccg tattcatgaa tttttcccag
     8161 aaaatcgacc aacacaagaa gatattgatt taatctacaa gcgtaaagac aaagcgccgt
     8221 ttcaaacggt agaatttgcg gatggtacga cagaagaggt ttggaatacc tttggggaag
     8281 aacaaattga tttagatgtg accaaagaag ttgtgaaaga atttattcga gaaaccatca
     8341 aagatatggc gaaccatggc tgttctttaa ttcgattaga tgcgtttgct tatgcgatta
     8401 aaaaattaga taccaatgat ttcttcgtgg aaccagatat ttgggaactt ttagacgaag
     8461 tgcgtcaaga agcagcgaaa tatgacgtcg aattattacc agaaatccat gagcattatt
     8521 ccattcaaat gaaaattgcc aatcatgatt attatatcta tgacttcgcc ttgccaatgg
     8581 tcactctgta ttcactttat agtggaaaat cagaacgttt agccaattgg ttgaaaatga
     8641 gtccgatgaa gcagtttaca acattggata cgcatgatgg aattggtgtt gtggacgctc
     8701 gtgatttatt aacagatgaa gaattggatt acacctctga ggaattgtat aaagtcgggg
     8761 cgaatgtgaa gaaggtctat tcaagtgcca attacaataa tttagatatt tatcaaatta
     8821 acagcaccta ttatagtgca ttaggcgata atgaccgtag ctatctgtta gcacgtgcga
     8881 ttcaagtatt tgcgccaggg attccacaaa tttattacgt tgggttatta gcaggaaaaa
     8941 atgatattga actgttggaa gcaacgaaag aagggcgtaa tattaatcgt cattactatg
     9001 atttagccga aattgaagaa gaagtgcaac ggccagtgat tcaacaatta tttgcacttt
     9061 taaaatttag aaatgaatct gcggcgtttg atttggatgg aacgattgaa gtagcaacgc
     9121 catcagaatc agaaatagtg attacacgta aaaataaaaa cggtagtgat agtgcaacat
     9181 taacggctaa cttggatacg aaagaattta tcattgagtc taaagatata aaaattttca
     9241 ctagtgttgc attaaaattt taacctattc catagaacaa aaaatccttt atactagcac
     9301 ttggatgact tatccaagac caataaaaag gactcataca tggataagta taaaacaaat
     9361 acagcattta ataaatggtt ttctgccata aaattaggaa aactttctgt caactcccaa
     9421 aaatgtattt ttgattacaa ttcgtatcgt aaaaaactgt cttttgaagc tgtgctcaag
     9481 ctctttctct acgcagttaa tgaagaaaaa gaaagtttgc gtgatttgag tacagctctt
     9541 atcgaccgat cgctccaact agaaaccgat gtgtcatcga ttagtcatac ccaattgtct
     9601 cgagcattta atgcacttga acctaaagtg ttagaagaaa tttttcaaca actgttagaa
     9661 aaagttcaac atcaaatcaa accaaccaag cgaaatcatc tgtatctgat tgattccagt
     9721 acgttttcgc ttagtttaaa acgtcataag tgggcgactt tccgtcaaac aaaatcaggt
     9781 gtcaagttac acttaaacta ttgttatatg gacgatacta cgatgtatcc aactgatttt
     9841 accttaacaa atgcccatga acatgatctc aatcaactac cagtattggt gaatcaacca
     9901 gaggcaactt acgtgtttga tcgtgggtat taggactttg aaaagatgga tcagatgcat
     9961 tgggatggct atttcttcgt cactcggatt aaaaaaaaca ccaaagttca cgtgatagat
    10021 actctggaaa catcgccaga aacagaaatt ctacgagacg agctggttcg tttaggatct
    10081 aaaacctatc taaccgccaa tttccgacta gtcactgttc aagataagaa cggacgtgtg
    10141 tttcaattta tcaccaatcg aatggacgtc tcttcaaaag aaatctctga tatgtatcac
    10201 gctcgttggc aaatcgaatt gtttttcaag cacatcaaac aacacatgac cattaaaacc
    10261 ttcttttctc aaagtgaaaa aggcgtgcag aatcaattga ttttaacgat gatttccgct
    10321 ctcctcacgt ttctcatcaa attggagacg aaaacggaaa aatcagtgtt ccaaatcaaa
    10381 cgattctttc gttatttact gtttcagccc tttgaatgtt gtctagaaaa attaattccc
    10441 acatgagaaa aaagaaat
//
LOCUS       DAFTHM010000090        10295 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFTHM010000090 DAFTHM010000000
VERSION     DAFTHM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.090"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            6..305
                     /locus_tag="L7C88_002220"
     CDS             6..305
                     /locus_tag="L7C88_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9559026.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="L7C88_002221"
     CDS             378..1739
                     /locus_tag="L7C88_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBP9559027.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="L7C88_002222"
     CDS             1761..2021
                     /locus_tag="L7C88_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559028.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="L7C88_002223"
     CDS             2035..2787
                     /locus_tag="L7C88_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBP9559029.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="L7C88_002224"
     CDS             complement(2881..3486)
                     /locus_tag="L7C88_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBP9559030.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="L7C88_002225"
     CDS             complement(3539..4513)
                     /locus_tag="L7C88_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBP9559031.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="L7C88_002226"
     CDS             complement(4891..5610)
                     /locus_tag="L7C88_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBP9559032.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="L7C88_002227"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="L7C88_002227"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBP9559033.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="L7C88_002228"
     CDS             7161..8558
                     /locus_tag="L7C88_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBP9559034.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="L7C88_002229"
     CDS             8639..9079
                     /locus_tag="L7C88_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBP9559035.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="L7C88_002230"
     CDS             9227..9553
                     /locus_tag="L7C88_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBP9559036.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..>10295
                     /locus_tag="L7C88_002231"
     CDS             9554..>10295
                     /locus_tag="L7C88_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559037.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAY"
BASE COUNT         3263 a         1819 c         2135 g         3078 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttatt
//
LOCUS       DAFTHM010000091        10193 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFTHM010000091 DAFTHM010000000
VERSION     DAFTHM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.091"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..968)
                     /locus_tag="L7C88_002232"
     CDS             complement(<1..968)
                     /locus_tag="L7C88_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBP9559038.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLK"
     gene            complement(959..1627)
                     /locus_tag="L7C88_002233"
     CDS             complement(959..1627)
                     /locus_tag="L7C88_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9559039.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            complement(2083..3069)
                     /gene="lacD"
                     /locus_tag="L7C88_002234"
     CDS             complement(2083..3069)
                     /gene="lacD"
                     /locus_tag="L7C88_002234"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBP9559040.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            complement(3082..4008)
                     /gene="lacC"
                     /locus_tag="L7C88_002235"
     CDS             complement(3082..4008)
                     /gene="lacC"
                     /locus_tag="L7C88_002235"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HBP9559041.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            complement(4021..4536)
                     /gene="lacB"
                     /locus_tag="L7C88_002236"
     CDS             complement(4021..4536)
                     /gene="lacB"
                     /locus_tag="L7C88_002236"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HBP9559042.1"
                     /translation="MKIAIGCDHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            complement(4555..4983)
                     /gene="lacA"
                     /locus_tag="L7C88_002237"
     CDS             complement(4555..4983)
                     /gene="lacA"
                     /locus_tag="L7C88_002237"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HBP9559043.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTRKHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            complement(5003..5776)
                     /locus_tag="L7C88_002238"
     CDS             complement(5003..5776)
                     /locus_tag="L7C88_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBP9559044.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            5941..6420
                     /locus_tag="L7C88_002239"
     CDS             5941..6420
                     /locus_tag="L7C88_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBP9559045.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            6477..6779
                     /locus_tag="L7C88_002240"
     CDS             6477..6779
                     /locus_tag="L7C88_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBP9559046.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            6801..8258
                     /locus_tag="L7C88_002241"
     CDS             6801..8258
                     /locus_tag="L7C88_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBP9559047.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
     gene            complement(8851..9603)
                     /locus_tag="L7C88_002242"
     CDS             complement(8851..9603)
                     /locus_tag="L7C88_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBP9559048.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
     gene            complement(9818..10054)
                     /locus_tag="L7C88_002243"
                     /pseudo
     CDS             complement(9818..10054)
                     /locus_tag="L7C88_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
BASE COUNT         2897 a         2234 c         1735 g         3327 t
ORIGIN      
        1 tgcttgagcc catgcactcg gtactgatga gaaaaaattg atgcctgttt ctcctgagga
       61 atgccaattc cctgatcttt tacttcaata atcacgctac ccttttggtt tgaaatggtg
      121 acaattacca gttttccttc accatatttg attgcattgt caactaaatt cgaaaccgcc
      181 cgataaatcc aacgatctcg tccatgaatc agggttggtt gatcttcagt aaacgcaaac
      241 aaaagattcg gataattcat tttgtaggca tcacaaactt ccgcacagat cagtgaaacg
      301 tctacgactt ccgtgctaag atcctctgag ttattggata atgtcaaaat atcgtcaata
      361 ctgtcggtca tccgatctaa aagcattaaa tttccttgat cggcatgttg ccgttctatt
      421 tccagattcg tacgcaaaat agcgatggca tttttctgct cgtgggtcag ataactattt
      481 aatcgtcgat aatcctccaa atgaccatcg aacttatcct ttagcttatt aaaagccgca
      541 tttaatgcct cgtccttcac agtattttta ggaacttgat caataaacgt taaatcacgc
      601 gtaatcgcta agatttgatt actgtaaatt ttgcgtaaaa ccaaccaaag aataaacgtt
      661 aataacatga cggcagaaca aataaccagc accatcgctg gtaaatattt aaatagttcg
      721 tcctggtaag ctttatctat catcgaaata gtcataaatt gattgttgga agatttcgaa
      781 gcttccatct gcgtctctgc ttgaaccgtc ttaccctctt ccataaaata aacatcttca
      841 cctaaggtag atgcgatact gattccctcc aaattatttc tcagaaagaa gaaactcact
      901 aaaatcacgc ctgtcaccaa cagtgaaaaa gccagcatcg ttaacgtcat tttaaaattt
      961 aatagcatag ctggtacccc tttgctcgaa tggtttttaa gacctctttt tcagctgctt
     1021 cagccagttt cttttttaga cgagccagat gcactcgcag aaccgacgaa aaaggatcaa
     1081 aatcttcatc gtagacatgt tcagaaattt cctcagacga aacaaccgct ggatgacgct
     1141 gagcgatgca cagtaagata tcaaattcct tgggtttcag gaccacctct gtcttttgat
     1201 agctgaccct tcgacctaat ggatcaatct tcaaagcacc aattgaaatc tgcggcagcg
     1261 cacgtccatg ataacgacga ataaccgcgc gtattcgtgc ttttaattct agtaactcaa
     1321 agggtttgac taaataatca tctgctccaa aatccaagcc ttttgctcgt tcttcaatct
     1381 catcacgtgc agtaataatg ataactggac tttcgacttc ttcagcacgg agactttgta
     1441 aaacagataa tccatctttt ttaggcagat ttaaatctag tagtatccca tcgtatgaat
     1501 tgatgaaggc cttctcttct cctgactcgc catcataagc tacatctaca gaaatattct
     1561 cctgctctag gccctttttt acggataaaa ccagctcacg attgtcctca accaccagta
     1621 cacgcatgta tattcactcc tcatacggat ttagtaatta cacttatgct ttttagcata
     1681 gtacacgctc ttcttcaaag tccacgttct ttttgtgaag atttgaagaa attcatacat
     1741 tctgttaaaa aacacataat taagaatgat tttactgttt gaaaatacct agaatagaaa
     1801 aagactggaa cctttcctcc agtctcacta ctttctattt gcttggtttt cttgtatata
     1861 cttttcaaag ttcgttggtt tatgaccaat aagcctcgtt agaatactga aaattgccat
     1921 caagtcatta agtaccacat gtaagaaaat ctctctaaag aaaaacccct tcgttttaac
     1981 tcacttacta ttttagaatt cgttccccta ataatgcagc atgattttac gctttatgta
     2041 taaaaaaaga ctgcaagcaa ttttgcttca cagtctgatt tcttatgata gtgagcttgt
     2101 taacacttcc accggtgtag cagtttcttt caatacggca tttaattctt caatattttt
     2161 acgcccttgc gtattcatcc actccatcgc tgcttctttt ccatcaacga tatagctttc
     2221 tacaccatct gcccaagtcg cacggccgca aagtacacca ttgaaggttg agccggcatt
     2281 tttcgcgaag cgcagtgttt cttggaacaa ctctgctttt acaccggcgc ttaggaaaat
     2341 aaatggcagg ttagtggctt cagcctgttc cttgaagaag ttagccgctt gtgcctttgt
     2401 gtacacgact tcgtctgtcc catagccttc cacataattc atattgacgg gtacttccac
     2461 ctttaacaca tctacgccat aacgtggatc agaaaattcc ttcatcatat cgttgacttt
     2521 atgaggtttc ttaatggcgt attctttcga agtcgcatca gagatgttcg cgtcataaga
     2581 aacaagctcc aagaagaagg gtaagttttc agcctgacat tctgagccga ttcgttcaat
     2641 aaaggcatgt ttttgattat tgatttcttc tgcttcatcg acatcatagt aaagtaggaa
     2701 cttacaagca tcggcgcctg cttcttttaa acgtttaact gaccagatcg ataataaatc
     2761 tggtaaacgg ccgggagttg acgcatcgta accagttttt tcataagcta acagcaagcc
     2821 ggcatttttt gctctaacgt cagctgctgg caagccatat tcgggatcta ataaaatcga
     2881 tgaggcatat ttcgttaatt gtgaagaaac aatttcttta aattcaacga tttctgattc
     2941 ttctgcttcg ctgcccttga attttgtgat catcttcttc aaagccccgc gttgatcaat
     3001 tgctaaggcc ccaatcactc catcttcatt gcatagttgc ttgatatatt gacgtttttc
     3061 ttcgttcatt tccgtatcct cctacacttt ctccactaag atttgatcat atagtttttg
     3121 ataattggct aattggacat agccagtcgt cgcttcctga gcattcagca ttcctaaaac
     3181 attaccctgt tttaacacgg cttcatccga aagaccttgt tgaatcgcag cggtcaatcc
     3241 ggcaacggtc gcatcaccag agccaactgg attgacgaca tcaatctttg gaattgtcac
     3301 gcaataaaaa gtctcgtgat gtttggcaaa ggctccgtcg ccccccattg aaaccactat
     3361 ccattcaatt tcatcaaaca tcgaatctga caaggcggct tttaaatctg ataattctgt
     3421 tgagatttct cgtcctagca gaccagccag ctcttcggta ttgggtttta ttagcttagg
     3481 ctttacactg cctcgcaaca cttcccttaa tgctgtacct gaacaatcta aaacgacagg
     3541 ctttggctga caaacttgca gcatttgtcg ataaaaatca gcaggcaatc cttctggcaa
     3601 gcttcctgaa aaagaaatga tttcggcttt aacagctaat ttttcgaaat gttgcaagaa
     3661 cgcccttgct tcttgttcag taataacagg tccgttttct aggatttccg tctgttttcc
     3721 gtcatgtaaa acagcgatgc aattacgtgt ctctccgctg ataggtaaaa agtcatgagc
     3781 aatctcattt tgagtcaggt cctttttaat ctcttcacct aaaaaaccgc cgattaaacc
     3841 actagcaatc acctccgtat ctaattgctt caagatacgt gtcacattta ggcccttacc
     3901 gccagctgtt ttgcgaacat ttcttactcg attgactgtg tcgagcttga aggtttctaa
     3961 tggataagaa atatcaatcg atggattcat cgttattgtt aaaatcattt gtccacccgc
     4021 ttaatcgtgg tattcgccac gatcccattt ctcgataaat tcatcgaaga aatgcggatc
     4081 agactgcttg tcactggctt tttcgacgtg atcgattttg gcgatcaatt ttttgttttc
     4141 ttcagtttct tgataatcgg cattgatgaa ggcctctaat atgtcacaga tcaaaaattc
     4201 tcccgtaatc cgagcgccaa agccgatcac attggcattt agttgttcct tcgcatagat
     4261 agcagtcgtc atatcgcgaa ccagcgcact gcggatacca ggtactttat tgacagcgtt
     4321 gttaatccca acacctgttc cacacaaaca aactcctaga tctgcttctc cgctagtcac
     4381 ggcctctccg actttttttc cgtagatcgg ataatgggtt ctggtaaagt cataggtccc
     4441 catatccaac acttcatgtc cttttgattt taagaaatct gatactgcca tttttgtatc
     4501 tgtgacgatg tggtcacagc caattgcgat tttcatttca ttcatccttc ctaattacgc
     4561 cattttattt aacatgtcga cacgtacttg atgacgacca ccatcataat ttgcttgtag
     4621 aaattcctta acaatattca acgccaactc atcgccaaca atttttgatc caagtgtgat
     4681 catccgagaa ttattatgtt tacgggtcat atacgcactg cgctcatccg aaacttctgc
     4741 tgctaccatt cctttaacct ttgttgccgt gataaagctg ccagcgccgt agccatcaac
     4801 cgcgattcct aaactacctt cgttttcatt cagatcattt gcgatcgcca aagttgattc
     4861 cacaaaatct tctgaagccg tttcactctt atctactact gtaatacctt ctttgatcaa
     4921 ttttttcttg attaattcct ttaattccat gccgtcactg tctgaaccaa ttactacacg
     4981 catttttgtt tcctcctatt ttttactgaa tgattttagt gaattgctga taataactct
     5041 tcagctcggc tgaaagagta gaatccgtaa ataatttgtc gatcttgcgc aaatcataga
     5101 aattataaaa atcgctatgg tcgaatttgt ttgcatctga aaccaaacat ttttctgccg
     5161 cattatctaa aacaattttt tgcaaggtac cttcttcaat actgaaattc gaaacctccg
     5221 aacccttcaa tccattcact ccgacaaaag ccttcttaat accgattttt tgaacagctt
     5281 cattggcaat tgaaccgaca aaggctccag tcttttcccg atatagccca ccgatcaaat
     5341 acagttcaaa tctttttatt tcacttaata gattgaaaac cggcagacta ttggtaacga
     5401 ttcggagaga tgacggcttg atgtatcgtg tcattaattc gatcgttgta cccgatccaa
     5461 gaaaaatcgt gtcgtcttct tgattgatat gagctgccgc atttttagcg atgtattcct
     5521 tctcttttgt atgcagcttc tttttttcag tatgagaaag ctcatttgct tctatagaag
     5581 tcgacatttc cagataatcg attttttgtg caccgccatg aacgcgtaaa agctttttct
     5641 tctgcgcgag ttcctctaga tctcggcgga tcgtcatatc tgaaacattc agtacttcct
     5701 gaataaattt gactgttatc gtcccatagc gatcacacat cgctaagatc gaacgctgtc
     5761 gttctgtttt cagcatattc tgtacctcca cgaccttata ataaaacatt tacgaacatt
     5821 tttcaacaca tattgttcgt ttattttcgt ttatgcgttg acaatgattt tgtaagcggt
     5881 tatactcaac ttgtaaacat ataaataaac ataaacgaac taataaagga gctgttttgt
     5941 gtgaatgaat tctttttcaa agacactgtc tatgtttctg acaagcagtc gcaggaagaa
     6001 gtgttcgagg aagtctatca agatctgtta aagaaagaat tggtaaccga agattttttg
     6061 gagaaccttt tagaacggga gcgtaattat ccgacgggat tagatctctc acctgtctct
     6121 aaaatattgc cagatatcgc tatccctcat accgaaagtg agtttgtgcg aaccacccgt
     6181 atcattccaa tcaaagtaaa aaatgaaatc cctttctaca acatgatctc gccaagcgat
     6241 cagatttccg cttcatttct tttcatgatc ttgaacgaaa atggtgaagc acaggctggc
     6301 atgttggcta atatcatgga tttcattaat tctgttgacg aagaaaaact gttttcgttt
     6361 ttcaaattag aggacacaga agcgatttat cattttttag aagaacattt ttatatatag
     6421 aagtctctgc ctaaccgcag gataaaaaat aaacttattt taaggggaga attattatga
     6481 tcaaaatttt agcagcatgt ggagcaggcg ttaattcaag ccatcaaatc aaaagcgctt
     6541 tggaaactga attgaaaaat cgtggctatc aagtcacctg tgacgccgtt atgatcaaag
     6601 atatcaatga agaaatgctg tctcattatg acattttcgc acaaattgcc aacaccgact
     6661 tgggttttga cattaacatc cctgtcgttg atgcaggtgc tattctttat cgtattcctg
     6721 ctatggctga gcctgtttac caaagtatgg aaagcgcaat ccaatcatta aacaaatagg
     6781 actaaagaaa ggaaaagcat atgaatacaa ttattgatat tgccaataaa gtatttaccc
     6841 ccctaattaa tttaggtgcg gcaccgttaa tgaccatcgt attaactgtt attgctttat
     6901 tttttaaagt aaaaccgtca cgcgctcttg aaggcgggct caaattaggg atcgccctga
     6961 ctgggatcgg agctattatt ggaattttaa ctactgcttt ttcagacgct atgacagctt
     7021 ttgttgaacg cacaggtatt tcattaaaca ttacagatgt cggttgggcc ccactagcaa
     7081 ccatcacatg ggggtcgcca tacacgcttt attttttact aattatggtg atcgtcaata
     7141 ttgtcatgtt agcaatgaaa aaaaccaaca cattagatgt ggatattttc gatatttggc
     7201 atttagcaat tgttggtttg ttcgcgatct tctgcggtgc taatctgttt attgcttctg
     7261 cattagttat tttcattggt gtattaaaaa tttggaactc cgacttaatg aaaccaacct
     7321 tcaatgactt gttaaatgcg ccagacagca acccgatgac cacgactcat atgaactaca
     7381 tgatgaatcc gattattatg gttttcgata aaattttcga caaaatcttc ccttggttgg
     7441 ataaatatga tttcgatgct gccaaattga atagtaaaat tggcttctgg ggatcaaaat
     7501 tcgcgattgg aatttatttg gggatttttg ttggattact agcaggacaa acaccaacgc
     7561 aaattttctc gctagccttt accgctgccg tctgtttgga attgttctct ttgataggcg
     7621 cttggttcat cgcagccgta gaaccgttat cacaagggat taccgatttt gccaataaac
     7681 gactaaaagg acgtaccatc aacataggtt tagactggcc tttcatagca ggccgcgctg
     7741 aaatctgggc tgccgctaac gtattagcac caatcatgtt gctagaagcc atcatcttac
     7801 caggaaataa attattgcca ctaggcggaa tcatcgcaat gggtgttacc ccagcactat
     7861 tggtcgtaac tcgtggaaaa ttaatccgta tgatcgtaat cggcgcgatc gaattaccat
     7921 tattcttatg gtccggcacc ttgatcgccc cgttcgttac tcaaacagct aaagcagtcg
     7981 gagcctttcc agccggcttg aacgggtccg ccatgatctc tcatacaacg atggaaggcc
     8041 cgattgaaaa attcctaggt tatttagtcg gtaatgcttc tcaaggacaa atcgaatttg
     8101 tgatatacgc tgccttagca ttaggtgcat accttttaat cttcatttgg tacgctcgtc
     8161 aaatgaaaaa acgcaacgct gcatacgcag ctgaaaaaga agagaatgca tctccggcaa
     8221 cggcgcataa tatgacttat gcagccgaag ctaaataagc taaaaacacc ccgaatgtct
     8281 ttagacttcg gggtattatt ttacctataa aaaataaata gatgtaaaat ccatttcaaa
     8341 aagcatagcc catctcttgc cacacccaat aaagaaatta tcaacgttta tgcttttttt
     8401 aactccttta agcttgcctt tgttggtatt cctcaacgat tctttttgtg ttcttgtttg
     8461 ttttgtgctt tttgactttt tgttgtttaa ttgcgaattc cttgatttct tttttcctga
     8521 atcgcttcgc atcccgcggt tatgcgtgcg atttcatcat tgctttttct gatctaactc
     8581 gtttcatgtc aaagagcttc agctgactta gtgtccatgg ttgttttgat atcccttttc
     8641 ctccttaata aagcggtgat tgatactgct attttttcct tcacataaac ataacatccc
     8701 aaaaaaatcg actatctttt ttcaaatggt gtattcaagt attcggagga attagtaatg
     8761 atgcacccta aaaataacat aattcgctta aattcaaggc taccaaaaaa ctaccaagtt
     8821 ctaattatct agagtttggc agtttctcat ttacacaaca tatttttctt ctttttcgat
     8881 tttttcatag tgcttttgtt catcatcatc cgttataact actgttacat cattcagatt
     8941 ataatatact gaaaaatctc ttttcccaat tttcgaatga tcaatcaata aaaagcgttc
     9001 aacagaatta ttcagagcga tctgttgagt ttggccctct tcaaaagtcg aagtcataat
     9061 tttctgttca tttaaagcat tacagctgaa aaatgcttta tgaaaattca tatcctgtag
     9121 cgatttattc gtgatttcac caacaaagca ttgagtcgtt tcccgcatct cgccacctaa
     9181 tagatagatt tttcgattcc cttttcgctt atttaattct tcaaaaacag gcaaacagtt
     9241 tgtaacaatc cgcagtgaat ccccttgaat gatttttgac atgagctcga ttgtagttcc
     9301 tggtccaaga aatatcgtat caccatcatt gatcatttca ttcgcctttt ccacaatccg
     9361 ctgcttttct tcttgcagca taatctgttt ttctctatga gaaagctcca catgccgata
     9421 aaaatccttc aatttcgctc cgccatggac gcgttctaat aatccttgtt tctccatttc
     9481 gtccaaatca cgtcggactg tcatatccga aaccgaaaac ttctccataa tatcgctgac
     9541 tcgtactgta ccgttaacct ctaataacga catgatcgct tggaatcgat ccgtttttaa
     9601 catttcatcg cctcttttct ttttaagact atcaaattct taagaaaagt gctagaacaa
     9661 gttttcttaa gaagccttct gcaggaagga aagcaaaatt tttcagaatt tgcaagctgc
     9721 tattctaaaa aataaaaccg aacgagcatg actgtcatag tgacagcctt gttcattcga
     9781 cttttatctt taataaatca ttttatttaa tctgaagtta ttgtgcaagt tcaaaaacaa
     9841 agtagttaat gtctcctcga tatttcgaaa tcgaatactc aacgggcaga cgttctagcg
     9901 aaaaaccctg tgtatggaaa tagaacattg gatctccttc ttccacatct aacaaatcgc
     9961 tgatcgtatc atccgctttg attacttcta gttttctggt gaccgtttta attggataac
    10021 ccatttcttc aaaaacttga tacatttttt cttttctgat ttgtcaaatt aagctagaca
    10081 atatgtcttt atctatgcag ctcaaaaata cttccaatgg tgttcgataa tttaatgatt
    10141 ttcttggaat atggtttctt ttcgaggcaa cggattgaat aaaggtttca tcc
//
LOCUS       DAFTHM010000092        10115 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFTHM010000092 DAFTHM010000000
VERSION     DAFTHM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10115
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.092"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            119..625
                     /locus_tag="L7C88_002244"
     CDS             119..625
                     /locus_tag="L7C88_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBP9559049.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            642..1541
                     /locus_tag="L7C88_002245"
     CDS             642..1541
                     /locus_tag="L7C88_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBP9559050.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            1628..2512
                     /locus_tag="L7C88_002246"
     CDS             1628..2512
                     /locus_tag="L7C88_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBP9559051.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(2704..2775)
                     /locus_tag="L7C88_002247"
     tRNA            complement(2704..2775)
                     /locus_tag="L7C88_002247"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2740..2742),aa:Arg,seq:ccg)
     gene            2835..4169
                     /gene="rpoN"
                     /locus_tag="L7C88_002248"
     CDS             2835..4169
                     /gene="rpoN"
                     /locus_tag="L7C88_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBP9559052.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            4318..5409
                     /locus_tag="L7C88_002249"
     CDS             4318..5409
                     /locus_tag="L7C88_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBP9559053.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            5450..6451
                     /gene="gap"
                     /locus_tag="L7C88_002250"
     CDS             5450..6451
                     /gene="gap"
                     /locus_tag="L7C88_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBP9559054.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            6561..7751
                     /locus_tag="L7C88_002251"
     CDS             6561..7751
                     /locus_tag="L7C88_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBP9559055.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            7855..8610
                     /locus_tag="L7C88_002252"
     CDS             7855..8610
                     /locus_tag="L7C88_002252"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBP9559056.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            8726..10024
                     /gene="eno"
                     /locus_tag="L7C88_002253"
     CDS             8726..10024
                     /gene="eno"
                     /locus_tag="L7C88_002253"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBP9559057.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT         3541 a         1871 c         2095 g         2608 t
ORIGIN      
        1 tttgtcacac cttctttttt gtatataaaa atcccaagta aatacataaa aaataaaaaa
       61 attgaaactt ttagcgcacc ttgtacgtca tattaagtga ggcagaaagg agtggagaat
      121 gatttttact ggatataaga aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg
      181 actcatcgaa actgattatc aaaaaatgtt ccgtatcacg atgaattacg tacatgataa
      241 agaagaggcc ttagatgtga tgcaagatag ttttcataaa gccctgaact attttgaaaa
      301 agaaaaagag atcgagcatt ttagtgcatg gttttatcgg atattgatcc gcacggcatt
      361 agatagttgg cgcagacaaa aaaggacgcc tgtggactta tttgaaattc aagatatccc
      421 ccaacagtta cctttagaaa cttccgttgc agagctccat atgattttag ataaaataga
      481 cagtccggaa aaagagattc tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat
      541 tgcgactatc ttggatatga atgaaaacac agttaaaacg aaaatgtacc gctcattgaa
      601 tgctttacgt caaatcctag aatgaaggag agaagagtgc catgtattcc caaaaagaaa
      661 atttaaaaaa actaaagaaa acttataaag aacaagcaat tcccaaaggg cttaaagagg
      721 agatccgcca gcgttttatt atcgaagagc aatcatttat aaaagcaaag cggagaaaga
      781 gacgtctcca agggttcgga gtatctttgg ctatcgtaat gattacaaca agtagccttc
      841 tttttaatag tcaagttcga agctttgcag aagatttacc catcttagga tcagtcattg
      901 aattgatctt aggcgaacgc tttactgatc gatctgaaaa aatcgatatt caggtaccga
      961 agatcaatac acaaaatgag aaagaaaata aaacaattca tggattaaat caaaaatact
     1021 ttcgcgaagg acaagcagat tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg
     1081 atcattacca agttttggga gattatcaga aaatcgtaga cgataaccgg tttctcgtga
     1141 ttgaaaggca gatcacccaa acagcagcag atagccatgt tgaaaaaaga tacgacacaa
     1201 tcgacaagaa aaacagtgtc cagctctcac ttccactttt attcaaagat gacacctatc
     1261 tatctgtttt gacaaaagaa gtcaaacggc agatggccga acaagtcaag gaagatccat
     1321 ctaagtacta ttggactgag caagatattc aagaagggac gatagaaaaa ccaacacttg
     1381 ttacgcctac acgaagtttt tatttgaaca aagagcatca attagttttg actttttctc
     1441 aatacgaaat tgctcctggt tatatgggta caccagaatt tgtcattcct aagtccgtga
     1501 caaaaacgat tttggcatcg gaagattatt tggatcatta gacgagaagt agttgcgact
     1561 agcagtttca attttcaagt aagtacaagt aaataataag aagagaaaaa gagaaagaag
     1621 agatatagtg aaaagaaatt atttagttat cagtattatt gctttatccg tgcttttgtt
     1681 tttcgaaatt acttcggtgg cctccttgat caccgaagta aaaggacaaa cacactcttc
     1741 ggagcattcg tcacaatctt tcaaacaatc agaacaatca accattaaaa gccaatcaac
     1801 tgaaacagct aacgtcaaag aagccattca agaatcagcg gaaaaggtac aaagtcagtc
     1861 atcacaatca acacaagaca gtacaaaaac gagccgagat ccggctgtca aaagcgtcgc
     1921 aatcagcttt gatgatggac caggagcgac cacaacaccg cagcttctgc gaatcttaaa
     1981 agaaaaaaac gtgcatgcca cttttttcgt cttaggagaa aatacggcgc agcatcctga
     2041 aatcgtgaag cagacagctg aagcagggca cgagattggc aatcacacat acgatcatca
     2101 gaatctggcc actctttctg cccagtcgat gacggaggaa gtgacgaaag cagacactga
     2161 gatcaaaaaa gtcactggca aaacccccac ttttgttcgt ccgccctatg gttctgtcac
     2221 gaatgtagga gcaacgatca tccagcgacc gatcatcgaa tggtctgttg attcagaaga
     2281 ttggaagaca agaaatcctg atttgatttt gcagaagatc caagcaacag tatacgatgg
     2341 ggcaattatt ttattccatg atatctatcc tgaaacgatt cgtgccgttc ctcaagtgat
     2401 cgattatctg aaagagcaag ggtatcgcat cacgacagtt ggggatttat tagggcatcc
     2461 aacggctgtc gagaactatt atggcagaaa cgatcatcgg ccagttcagt aagtgagaca
     2521 agtatcttta ataaataaca cattttaata agtagttgaa cacataacta ccttacttgc
     2581 aaaggcttaa caatatctat acaggtacaa caaaaaactg tccaccaatt ttctttggcg
     2641 gacagttttc acttaaaaat aaagaagcaa ctattcgtaa attatgctaa aatagcagta
     2701 gaacgcgtcc tgagggaatc gaacccccgt ctcaagaacc ggaatcttac gtgatatcca
     2761 ctacactaag gacgcaagca ctgggataat tgtaactaaa cagataaaaa attacaaggg
     2821 gattggacaa aaaaatgaaa tttgagcaaa atttttcaca aaaacagcag cagacacaga
     2881 aactagccat gacgcaacag ttgcaacagt ccatccaagt tttacaatat aacagtgagg
     2941 agctgttggc attcgttgag aatcaagcaa tggaaaatcc attggtggaa gttgttgagc
     3001 cggaatggca gccagattac ataaaagctt cttcatcttc ttatgaagga gaagagacaa
     3061 attacctaaa tcagattcct gatacaaaag ggtctttatt tgattcattg atcgaacaag
     3121 tccatttgaa ttaccgagat acttttttga ggaaaatcgt tctttatctt gtagaataca
     3181 tcgatttgaa cggatttttg acgattagtt tagaagaagc cggaaaagag attggagcta
     3241 cgcctatcca aatgctcgat gcgttgactc tgattcagca attagaacca gctggagtag
     3301 gtgcacgtag tttgcaagaa tgtctcatgc ttcaaacaga acgagatgat tatgcgccgg
     3361 aattagctta tatcgtgttg gaagaatgtt ttgaggaact ggtggagcga aaatggaaag
     3421 aaatcgcaca acgtttttct gttgatctac atgctgttca gcagatattc gactatttac
     3481 aaacgttgag tccaagccct ggccggattt tcgaccgtag cagcgaattg tacattattc
     3541 ctgatgtccg ggtattagtg gacgacgata aaaatgtaca agttatctca aaccgaaaaa
     3601 atcagccaaa tatacgcttt caagagagtt acttcaaaca aatgtcacaa caagcagata
     3661 aagaaactga aaattattta aaagaacgga aacaggaatt cgaatggttg aagaaaacga
     3721 tcctacaacg tggggataca attttgcggg ttgctcaagt cattgtttcc cggcaaaaag
     3781 ctttctttat cgacaaggaa cgtccaatca agcctcttac gttaaaggaa gttgcaactg
     3841 agatagatgt gcatgaatcc acggtcagtc gtgcagtcaa cgggaaatat ttggaaacag
     3901 acttcggtgt atttgaatta aaaaaatttt tcactacacg aattcctacg aatagtacag
     3961 aacagacaga agacctttca gcagatacag cgaagaaaaa gctgcaggaa ttagtcgatc
     4021 aagaagacaa aaacaagccg ttgtctgacc agaaattggt tgaattgctg aaaaaagatg
     4081 agatagcgat ctcaagacga acagtagcaa aatatcgtga tttattagga atcccgagtt
     4141 catcaaaaag aaaacgttat gataactaat cagtcaaaag actagaaaaa gtatttcact
     4201 ttttctagtc tttttagttg aaaaacgaga gcaaaactgt tagacttaca gtcgtgaggt
     4261 tgagatttcc ctttattgat gtgaaattcg aatagttaat ttcttttttt atcgtatatg
     4321 ggtcgtttta agtctacatt ggacgtaaag tgtccaacta aggagatcgc tatgctggat
     4381 gaaataaaaa tgattgaatc tgttgcacca gatattatcg aagtgttgca agaacgctat
     4441 aaaattttac gaaatatcta ttggatgcag ccgattggac gtcgaagttt atcggaaagt
     4501 atggggatca cagaacgagt attgcgaaca gaaacagatc ttttgaaaaa tctgaatttg
     4561 atcgacacct caaaaagcgg tatgacgctg acaactaagg gcgaagaagt ttatcaaagc
     4621 cttgaaaact tcatggatca gcttttaggt acgcatcaaa ccgaacaaca gttggcagaa
     4681 tattttggta accaacgctg tatcgttgtt tcaggaaaca gcgaagagca gaccaaagtg
     4741 gctgatgcat tcggcgaagc gctgagcgaa gccctagacc gactacttcc agaaggcgag
     4801 aatatcatcg ctgtgatggg aggaactact atggctgtgg tagccgaaca attgtctaat
     4861 ctggaaaata agaaacggca taacctgttt gtccctgcaa gaggcgggat tggtgaagcg
     4921 ataactgtac aggcaaattc tgtcagtgca agaatggctg ctaaagcaaa cggtaaccac
     4981 cgtgcacttt atgttccgga acaattaagt ctggcaactt acaattcttt actcaatgag
     5041 ccatctatcc aagaagtctt aaacttgatt agtgaagcga attgtgttat tcatagtatt
     5101 gggcgtgcat tacacatggc agcacgtcgt aagatgactg aaaaagaatt agtcatgctg
     5161 aaacaagcaa atgctgttgc ggaatctttt ggctactttt tcaatgaaaa aggtgaagtc
     5221 gtttataagg tccctagaat cggcatagaa ttgcaagatt tggaaaaagt cccgatcatc
     5281 atggcaatcg cgggcggaaa atcaaaagcc aaagcaattc gagcttatat gaaaaatgca
     5341 ccaaaacaaa cgtggctcat cactgatgaa gctgctgcaa atgagatttt aaaaggggta
     5401 accctttaaa ataaatattt ttttgatttt cataaggagg aaatcttaaa tgacagttaa
     5461 agtaggtatt aatggttttg gacgtattgg acgtctagca ttccgtcgta tccaagatgt
     5521 agatggaatc gaagtagtag caatcaacga cttgacagat gctaaaatgt tggcacactt
     5581 gttaaaatac gacacaactc aaggacgttt caacggaaca gttgaagttc atgaaggttc
     5641 attcaacgta aacggaaaag aagttaaagt attagctaac cgcaacccag aagaattacc
     5701 atggggcgaa ctaggcgtag atatcgttct agaatgtact ggtttcttca cttctaaatc
     5761 agcagctgaa aaacatttaa cagctggtgc taaacgcgtt gttatctctg ctcctggcgg
     5821 aaacgatgtt ccaacaatcg tttataacac aaaccacgaa acattaactg gtaaagaaac
     5881 agttatctca ggtgcttcat gtactactaa ctgtttagct cctatggcta aaacattgaa
     5941 cgacaaattt ggtgttgttg aaggattaat gacaactatc cacgcttaca caggtgacca
     6001 aatgactcta gacggacctc atcctaaagg tgacttccgc cgtgcacgcg ctgctgctgc
     6061 aaacatcgtt cctaactcaa caggtgctgc taaagctatc ggtttagtaa ttcctgaatt
     6121 gaacggtaaa ttagacggag ctgctcaacg tgttcctgta ccaacaggtt cattaacaga
     6181 attagtaaca gttcttgaaa aagaagtaac tgttgacgaa atcaatgcag caatgaaaga
     6241 agcttcaaac gaatcttacg gatacaacac agacgaaatc gtttcttcag atatcgttgg
     6301 tatgacttac ggttcattat ttgatgctac acaaactaaa gtaatgacag ttggcgacaa
     6361 acaattagtt aaaactgttg cttggtacga caacgaaatg tcatacactg cacaattagt
     6421 acgtacttta gaatacttcg ctaacttata agatagacaa acgtacaagt gtaaattata
     6481 gacatgtaca tttaaaagcg gggaagcaat cgcgcttctt ccgctttttt tgataataag
     6541 tttattcagg aggaaataaa atggctaaga aaacagtgaa agatatcgat ttaaaagaca
     6601 aaaaagttct tgtccgtgtt gacttcaacg ttcctttgaa agacggcgtg atcactgacg
     6661 acactcgtat caaagcagca ttgccaacaa tcaactacgt tctagaacaa ggcggaaaag
     6721 caatcctttt ctctcacctt ggacgtgtaa aaacagaaga agataaagaa ggaaaatctt
     6781 tagctccagt tgcaaaacgt ctaggcgaat tattaggtaa agaagtaaca ttcgtacctg
     6841 aaactcgcgg agaacaatta gaagaagcaa tccgcaacat gaatgacggc gacgttgtcg
     6901 tattcgaaaa tacacgattt gaagatattg acggtaaaaa agaaagcaaa aatgatacag
     6961 aactaggtaa atactgggct tcattaggcg atgtatttgt taacgatgct ttcggtacag
     7021 ctcaccgtgc acatgcttct aacgtaggta tcgcttcaac tggtatccca acagttgctg
     7081 gattcttgat ggaaaaagaa atcaagttca tcggtgaagc agtagaagaa ccaaaacgac
     7141 caatgattgc aatccttggt ggcgcaaaag tttctgataa aatcggcgta atcgaaaact
     7201 tgattcctaa agcagataaa atcttgatcg gtggcggaat gacttacaca ttctacgaag
     7261 caaaaggaat caagatcggt aactctctag tagaagctga taaagtggaa ctagcaaaag
     7321 aattaatcga aaaagcaggc gacaaacttg tcttgccaat cgacaatgtc tgtgcaccag
     7381 aattttcaaa tgatgttgaa acacaagtaa tcgaaggaga cattcctgat ggtttgatgg
     7441 ctttagacat cggcccagca tcagtaaaat tatttgctga tacattacaa ggtgcaaaaa
     7501 cagttgtttg gaacggacct atgggtgtat ttgaaatgag taactttgct aaaggtacaa
     7561 tcggtgtttg tgaagcaatc gctaacttag aaggcgcaac aacaatcatc ggtggcggag
     7621 actcagccgc agcagcagaa caattaggat ttgctgacaa attcacacac atctcaacag
     7681 gtggcggcgc aagcttggaa ttgcttgaag gtaaagaatt accaggacta gcagcaatca
     7741 acgataaata aacgaccaag tttgctcaat tctgacgagt aatcgatcaa aaggtgaagg
     7801 gagttttcat gactccctag ccatttttca ataaattaag gagtgtgttc ctcaatgcgt
     7861 aaacctatta tcgcaggtaa ctggaaaatg aacaaaactg catcagaagc aaaagaattt
     7921 gctgaagcag taaaaaacaa aatcccttca aatgacaaag ttgattcagt catcggatct
     7981 cctgcattat tcttacaaga attaatgaca tcagctgaag gtacagaact aaaaatctca
     8041 gcacaaaact gctactggga aaactcaggt gcgttcactg gtgaaacttc accagcagct
     8101 cttgctgatc taggtgttca ttatgtgatc atcggacatt cagaacgtcg tgaatatttc
     8161 catgaaacag acgaagacat caataaaaaa gcgaaagcta tctttgcaaa tggtatgaca
     8221 ccaatcctat gctgtggcga atctttagaa acctatgaag caggcaaaac tgctgaatgg
     8281 atcgaaggac aaattacagc tggtttagct gatctttcag ctgaacaagt gtcaaacatg
     8341 gttattgctt atgaaccaat ctgggcaatc ggtactggta aatcagctga cgcacaaatc
     8401 gctgacgaaa tttgtggagt tgtacgtcaa acagttgaaa aactttatgg aaaagaagta
     8461 tcagaagcag ttcgtatcca atacggcggt tctgtaaaac cagaaaatat tgctgaatac
     8521 atggcaaaag aaaatgttga cggtgcttta gtcggtggcg caagcttgca agcagattca
     8581 ttcttgtcat tgttagacgc tgtaaaataa ttgttgaaaa tttgcgaaaa atgcaagaaa
     8641 tgtttgcact aatgagcaaa attaactaaa atcgtatatg agggaaatcc cttaggaaaa
     8701 aacaaactca aaggagagac aaaacatgtc aattattact gatgtttacg ctcgcgagat
     8761 cttagactca cgtggtaacc caacaatcga agtagaagta tacacagaaa gcggagcttt
     8821 tggccgcgga atggttcctt caggtgcttc aactggtgaa tacgaagcag ttgaattacg
     8881 tgacggagac aaagctcgtt atggcggtaa aggtgtaact aaagctgtcg acaacgtaaa
     8941 caacatcatt gctgaagcaa tcattggcta cgatgttcgt gaccaaatgg ctatcgacaa
     9001 agctatgatc gctttagacg gaactcctaa caaaggtaaa ttaggtgcga acgctatttt
     9061 aggtgtttct atcgctgttg cacgtgcagc tgctgactac ctagaagtac ctttatacca
     9121 ctacctaggc ggattcaaca caaaagtatt gccaacacca atgatgaaca tcatcaacgg
     9181 cggatcacat gctgataact caatcgactt ccaagaattc atgatcatgc ctgttggcgc
     9241 tccaacattc aaagaagctc tacgtatggg tgctgaagta ttccacgcat tagcttcaat
     9301 cttgaaagct cgcggattag caacttctgt tggtgacgaa ggtggatttg ctccaaacct
     9361 tggttcaaac gaagaaggtt ttgaagtaat catcgaagca atcgaaaaag ctggctatgt
     9421 acctggtaaa gacgttgttc ttgctatgga tgctgcttct tcagaattct acgacaaaga
     9481 aaaaggtgtt tacgtactag ctgattcagg cgaaggcgaa aaaacaactg acgaaatgat
     9541 caaattctac gaagaattag tttctaaata tccaatcatc tcaatcgaag acggattaga
     9601 cgaaaacgac tgggacggat tcaagaaatt aactgacgta ttaggcgaca aagttcaatt
     9661 agttggtgac gacttgttcg taacaaacac tcaaaaatta tctgaaggta tcgaaaaagg
     9721 aattgctaac tcaatcctta tcaaagtgaa ccaaatcggt acattaacag aaactttcga
     9781 agctatcgaa atggctaaag aagctggcta cacagcagtt gtatctcacc gttctggtga
     9841 aacagaagat tcaacaatct ctgatatcgc tgttgcaaca aacgctggcc aaatcaaaac
     9901 tggttctcta tcacgtactg accgtattgc taaatacaac caattactac gtatcgaaga
     9961 ccaacttggt gaagttgcag aatacaaagg tttgaaatct ttctacaact taaaaaacaa
    10021 ataattcttt tctaatgaag atacatgatc gactattgaa agatagtcga gtatgatcac
    10081 ttagttaagt aatcgaactc tctacttgct gaaat
//
LOCUS       DAFTHM010000093        10091 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFTHM010000093 DAFTHM010000000
VERSION     DAFTHM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.093"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            274..3501
                     /gene="fss3"
                     /locus_tag="L7C88_002254"
     CDS             274..3501
                     /gene="fss3"
                     /locus_tag="L7C88_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBP9559058.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            3614..3928
                     /locus_tag="L7C88_002255"
     CDS             3614..3928
                     /locus_tag="L7C88_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBP9559059.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            3941..4315
                     /locus_tag="L7C88_002256"
     CDS             3941..4315
                     /locus_tag="L7C88_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBP9559060.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            4325..4660
                     /locus_tag="L7C88_002257"
     CDS             4325..4660
                     /locus_tag="L7C88_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBP9559061.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            4743..6083
                     /locus_tag="L7C88_002258"
     CDS             4743..6083
                     /locus_tag="L7C88_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBP9559062.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            6161..6835
                     /locus_tag="L7C88_002259"
     CDS             6161..6835
                     /locus_tag="L7C88_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBP9559063.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            6828..6992
                     /locus_tag="L7C88_002260"
     CDS             6828..6992
                     /locus_tag="L7C88_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559064.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            7068..8210
                     /gene="dcm"
                     /locus_tag="L7C88_002261"
                     /pseudo
     CDS             7068..8210
                     /gene="dcm"
                     /locus_tag="L7C88_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            8200..8490
                     /locus_tag="L7C88_002262"
     CDS             8200..8490
                     /locus_tag="L7C88_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559065.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            8749..9933
                     /locus_tag="L7C88_002263"
     CDS             8749..9933
                     /locus_tag="L7C88_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBP9559066.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            9930..10067
                     /locus_tag="L7C88_002264"
     CDS             9930..10067
                     /locus_tag="L7C88_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBP9559067.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
BASE COUNT         3340 a         1690 c         2267 g         2794 t
ORIGIN      
        1 ttcgtatcat tgaataagtt tgaaaaacct tgatttataa aggttttccc gtaaatatat
       61 tttattatat ttgattaaat ttgaaatgtt tgtgttctaa aatgtgttct aatttaaagg
      121 cagtatattt cgtattttag attaaatttt taggctcatt cattctcaaa tccattctat
      181 tcagtcaata aaaattttaa aaagacttta taaacaaaga tgttcaagcg agcatcttat
      241 ttttttgtgc ttaatttgaa aggagaacat ttcatgtata aaaaacaaaa aaagaaatta
      301 tgtgtattaa ctattttgag tttggctgtt caagcaattg ttggagcaat tgctcctacg
      361 attacttttg ctgatgaaat tacccatcca caaacggtaa ccgtagaact agatttagca
      421 catcaatatg ctgttgaagg aacttttagt gatggtcgtc caatgtcaga agtcactgtt
      481 ccgcattatg cagtgtacaa cggctttaaa caagatattt tctgtattga accaggagtc
      541 ccgatttaca atgagttcac tcctggctat gagaaaaacc cgttaccaga tatgtccgat
      601 aaagccaaat tagtttccgt tttatggaaa aaagtaggta cagatgcaga tactcatatt
      661 gtggcacaga agatgatctg gcaagaagtt aatgggtata cccttcactc aataaaacga
      721 tcagatggta gtgccgtaaa tatcgcagcc attgaggcaa aaataaatca agccattgac
      781 gattatcaga agaaaccaac cttccataat agtacggcta aaacagtatt agggcaatcg
      841 actactgtga cggatacgaa taatctgaat ttgtcagagt tcgatgaggt tgtggaaaat
      901 gccgcaaaca ttgattatcg tgtgaatggt aatcagttga taatcacccc aaatgccaat
      961 tcaaaagaaa gtggtgtgct gacgcttaag aaatctgctg gtaccggaac acctgtcgcc
     1021 tataaaaagg ctggccaaca gactttaatg gccggggcga ttgataaacc taatacctac
     1081 acaatcaaaa ttgatgtgga aacggagggt tctttaaaga tcaaaaaagt cgataaagaa
     1141 tcgggtgatg ttgtaccagg aacggttttc catttagact ttggaaaaac tttacctgca
     1201 aaagacgtga ctactgacaa agaaggcatt gctacattgg atgagattcc tcatggtaca
     1261 aaagtaacca ttaccgaaaa atcagtaccg gcgccttata cgattgatac cacccccatg
     1321 actaccacca ttaaagcagg cgaaaccatt tacgtgactt caaaaaacgc acgggaaaaa
     1381 gggcaaatca ttctggataa aagcggagtt gaaacaggga gtgatctttg gaatgacaat
     1441 tattccttag ctggtaatac gtttgccatt cgcaaagaca gtccaaccgg tgaaatcgtt
     1501 caagaaatga ccacggatga aaacggtcat gcggaaacac caaaagagat tgctaatgcg
     1561 ttggaattgg gaacctatta tgtgaccgaa actaaagcta gtcatgggtt cgtgaatacg
     1621 ttcaaacctg taaaagtcga attgaagtat gccaatcaaa ccgtagcccc tgttaccagt
     1681 aacgtaaaag ggcaaaatca agaagtcact ggcgaaacca ctttgacgaa agaagacaaa
     1741 gatactgggg ataaagcaca aggtaaggca gtctttgagg gtgctgaata caccttgttt
     1801 actgctaagg atggaaaagc tgttaaatgg agtgaggctt ttaaaccaga gttagcgaag
     1861 ggaacgaaag gttctgatga aacggtcact ttgactttag acgaaaagaa ccaagttgcc
     1921 gttaaacatt tagctatcaa cgagtattat tggcaagaaa caaaagcgcc cgaaggatat
     1981 agccttgatg aaacaaagta tcctgtatcc atcaaaaagg tggatgatag cgaaaaaaat
     2041 gccgtgatta cccgaaatgt tacggcaaaa gaacaagtga ttcgctttgg ctttgatttc
     2101 tttaaatttg ctggatcagc tgcgggcact accgaaactg gcttcaatga tctgaccttt
     2161 aaagtgtcgc cattggaagg gaccaatgaa atcacaggtg ccgaagatga agcgaccaca
     2221 gcttataacg agcaattagg gtttgatggt tatggcaagt ttgaaaatct tccttatggg
     2281 gattatttac ttgaagaagt agaagcccca gaaggttttc aaaagattac gccattagaa
     2341 atccgttcta cttttaagga aaacaaagaa gactttgtga agagtgagta tgtctttacc
     2401 attaccgaac aagaccaaaa acaaccaatt aaaacggtga ccgttcctta cgagaagctg
     2461 acgaacaaag cattttctgt tagtttgaac cgtttaatgc tctatgattt gcctgaggaa
     2521 gaagatagtt taacttctct tgcgacttgg aaagacggaa acaaagaatt aacttctctg
     2581 gattctaccg agctagttga taaattgagt tacaatctac atgaaatcaa agaagactgg
     2641 tatgtggtag cgcaagccat tgatgtggat gcgacaaaag ctgcccaaga aaaagatgaa
     2701 aaagccaaac cagtggtgat tgcagaaaca agcgcaacgt tggcgaacaa agagaaaaca
     2761 ggaacttgga aaattcagca taaattaacc gccgaacaag ttttaaataa aactattgtc
     2821 ttattcaact atgtgtatga aaataaggaa gcttttgaag caggcgataa gccagtagcg
     2881 aaggatgtta gcttgaataa ccaagcccaa actgtcagtt gtacagtgga acaccatgtt
     2941 tctatccaaa caaaggccca cctagaaaac ggttctcaga cctttactca tggtgatgtg
     3001 gtggatatgt ttgatgatgt gtcgattact catgatgtac tggatggctc aaaagaagct
     3061 ttcgaaacaa ttctgtatgc tttattaccg gatggtacaa acaaagaaat ttggaaatct
     3121 ggcaagattg attatgaagt aaatgataaa gaattcacca aaactgtgct tgcgaaaaaa
     3181 gtagataccg gaaaatatcc agaaggaacc aagtttactt ttgcggaaat caattacgat
     3241 aaagatggga atatcaatgg aaaacacaat gaagatttga aagaaaaatc tcaaacctta
     3301 acaccaaaag aagttccaac catactaagt acgccgaaac aaccggaaac accaactgtt
     3361 ccaagtggct ctcaagaatc tagtcccaca gtgaagacct tccctcaaac cggggagaaa
     3421 aattccaatg ttttactgtt cattggtttt actttgattt ttgcgacggc gggctattat
     3481 ttctggaatc gccggaacta aggtgatgag atgatacaag taaatcctaa gaaccaacgt
     3541 gcgcgaccgc ctcctaaaaa agtagtcgcg ctatttttgt atccaaaact aacaatgaaa
     3601 agaggaaaag aagatggaat tgaaatttgt cgtgccagat atggctgaaa cctttggaaa
     3661 gttaagttat gccggtgaag gagaaattat aacagaagga tatggacgga atactacggt
     3721 gattggtcgc agttatcatt tgtattccag taagcaacgg gccgatgata ttgaggtggt
     3781 agtagctgcg gaagccggtg aaaaggattt tgatcaagac caaccgctaa aagccgtgaa
     3841 tccccatttg gttgccaaag gctatgagat tgagaatcgt gggtttactg attacgtgtt
     3901 gtatgttgat gatttagtga aagcatagga ggaaaagaag atgagattaa cagaaggtat
     3961 tgtcgtagat tcaggtttaa catttgggaa gttgcgtttt tccgcattac gccgagaagt
     4021 acggaagcaa aatgaggatg gaacaattgg taatgaggta aaagaacgaa cctataattt
     4081 aaaatcctct gcacaagggc gaatgattca agttagtatc ccagctaatg tacccttacg
     4141 cgagtttgct tatgatgcag aggtagagtt ggtcaatcca atcgtggata ccgttgccaa
     4201 ttatgttttt cgagaaggaa ctaccgttaa ttggttcatt aaggcggatg atttagtctt
     4261 gaagcggcag ccgaatcaag gaaatcctac gaaccaaaat gaaagaaaga aataggtgaa
     4321 gattatggaa attaatgttg aacatatttt agattgtctc gatcaatatg gaaaaggcga
     4381 gctgactgag gaacaactcg ttaaagcatt aacctctgat gaaaaaatgt ttctgattat
     4441 acatcaaggt ttacttggag aaaatagcga cagtgaagaa gactctgatg tactagactg
     4501 gttaggagaa gaagagtctt tctttatagt tgtcgaagta aatgaaaact tatgtcggca
     4561 ggcagaatcc attttggaag aaattggtgt ggagatgccg gatgctattg aaggcttttt
     4621 aaatcaattg gttgaaacga aacaactccc ctcctcgtag cagtaaatga ctagcataac
     4681 tttttgaaat tgcctaatga aatcctattg ggctttttcg attggaggtg gaaaccatca
     4741 aaatgtacaa aggacatcgc atacgcgcag gagatcagca cttggtttat cactttgttc
     4801 ttggctggct actcgctctg ttcatcggtt ggatgagcgt cttttatttt caagagttta
     4861 gacaatttga tatttctaag ctatcacttt ctactattga aatcgtttgg tctataaaag
     4921 atttagtatg tctgcttgga agtctcgctt tttcaggagc tatgatattg ctttatattc
     4981 acttttttct tgatcattgg cgaagcttgt ggcatcgaca aaagctagct cggatgattc
     5041 tagagaacca ttggtatgaa gtgaaacaaa ctcaaagtga aggctttttc aaagatttga
     5101 atagtagccg aaccagagag actatcagtt acttccccaa aatctgttat cgaatgaaag
     5161 atggattact gtctattcgc gttcaaattt cacttgggaa ataccaagat cagcttttaa
     5221 aattggaaaa gaagttagaa agcggactgt attgtgagtt agtagaaaag gaactcaaag
     5281 actcctatgt ggagtatact ttactgtatg atatgatcgc caatcgaatt gggatagacg
     5341 aagtagtggc agaaaatggg actctgcgat tgatgaaaaa tcaagtatgg gcttatgatt
     5401 ctttacccca tatgttaatc gctggtggca cgggtggagg gaagacctat ttcctcctca
     5461 ccattatcga agcactattg aagtcagatg cagaattgtt tatcctcgat cccaaaaatg
     5521 cagatttagc tgatttaggt acggtgatgc ctcatgttta ttcacaaaag gaagaaattt
     5581 ctgcttgtgt ggaagatttc tatgaacgta tgatggctcg tagcaaggca atgaaagaaa
     5641 tgtctaacta caaaacagga gagaattatg cctatcttgg acttccaccc aactttttaa
     5701 tctttgatga atacgtggct tatatggaga tgttaacgac gaaagaaagt gcggtgattt
     5761 tgaataagct caaacaaatc gtgatgttgg gtcgtcaatc tggtttcttt ctgattttgg
     5821 cttgccaaag gccggatgcg aaatatttag gagacggaat ccgcgatcaa ttcaactttc
     5881 gcgtggcttt gggtcgtatg agtgaactcg gatattccat gatgtttggg gaggtcgaaa
     5941 aaaacttctt tatgaagcac atcaaaggtc gaggttatgt ggatacaggt ggcagtgtga
     6001 ttagtgagtt ttatacgcca cttgtaccaa aagggtatga tttcttagat tcaattagta
     6061 aattagaaaa gatgaatgat tgagtgatct tcaatactga ctttatactt caagtaacgt
     6121 ataatacttt tatatagtag gaagaaaggg gataattaat atggaaagta atgattctta
     6181 tttagagtat gcaaaagcaa ataaggataa gtttatttct tatattatca aagggaaatc
     6241 ccccgaagtt ggacgagacg cagtttttat ggcagggagt cctggggctg gaaaatcaga
     6301 ggttgccatt ggattagctg agaattatga taaccatgtg attattgatg cggattactt
     6361 tcgcacccag tttcctgatt ataatggaaa aaactctagt ctctttcaaa aagcatcttc
     6421 ttggttggta gagcaggcat ttagatatgt cttagatcat ggctattctt ttattctgga
     6481 tgcaactttt gcaatattaa gtgctgaaaa aaatatctcg cgggcgttga aaaaacattt
     6541 tcgagtgacg attttctatg tttatcaaga ccctaaaatc gcttggaaat ttacacaaga
     6601 acgtgaaatt gcagagggac gtcatgtgcc gaaaaaggca tttattaacg cttttttcaa
     6661 atcaagagag aacattgcaa aagtaaagag taaacatcca gatgtattgc ttcatatcat
     6721 aataaaagat tatacgaata atatttccga agttcattat gctacggata atctagaatt
     6781 atttttacca ctagggtata gtaggaaaga tttggaggtt caattacatg actgagaaag
     6841 aacaagtaac gaaaattgta aagaaataca ataagagcat tgcggattta tcggaaaatg
     6901 ctactgcaaa agagttcaaa acggtgatta aatatgtagc cgatcaggcc aatgaaaaac
     6961 aacggaaatt agttggatta aataaaaaat agtaggacaa attaataatg tatgagccaa
     7021 gagcaaaatg ttcttggctt ttttctttgc aatgaatgag gtaatgtatg agatttttag
     7081 atttattcgc cggtattggt ggctttcgtt taggtatgga acaggcgagc catcattgta
     7141 tcggtttttg tgaaattgat aaatttgcta gacgtagtta taaagcaatt catgatacaa
     7201 gtaaggaggt ggaaatgcat gacatcacaa gtgtatcaga tgagtttatt caatccctcg
     7261 gaccagtgga catcctttgc ggcggatttc cgtgccaagc tttttcaatt gcgggaaagc
     7321 ggcaaagatt ttccgatact cgaggtactt tattctttga aatcgctcgg ttcaccactc
     7381 ttctccgacc taagctttta ttccttgaga acgtccgagg attgctcaat cacgaaggag
     7441 gggctacgtt cgagacgatc ctccgaacgc tggatggatt ggggtatgac gtggagtggt
     7501 aggtgcttaa ctcaaaggcc tacattcccc aaagccggga gcggatattc cttatcggac
     7561 attctcgaga cgcatgtacc gaacaagtat ttcctatcat tggaccgtct tcaacatctg
     7621 atcaaaacat cagaaatttg gtaaatatca atccttccaa tcgaggaatg ggtggacaag
     7681 tctatggttc agatggcgta gcgccaacct taacaggtga tgaaggaatc aaaatcgcac
     7741 tgccagcaag ggatggaatc tctgtagcag gactattacc gggaaagttt gaacaaggta
     7801 atcgagttta tgaagttact ggaaccgccc ccaccttgtc aacgaaacaa ggtggtacaa
     7861 aaatcatgat tcgaaaaaat gaaacagaat atcaagaggt gaagccagaa gacagtgtga
     7921 atctggcttt tcctaattcc acaagtcgcc gaggtcgtct gggaaaacag agtgttcata
     7981 ccttactaac aggagaccaa caagcgatcg tcacggatca gtatcaaatt cggaagctaa
     8041 cacctagaga gtgttggcga cttcagggct ttcccgattg ggcttttgat cgagattctc
     8101 aagtcaattc agatagtcag ttgtataagc aagccggaaa ctctgtaaca gttccggtca
     8161 tttttgatat tgccagaaga ttaaaagagt tggatgtaca tggtttatga tgagttgatt
     8221 ggagaaattt attgggtgat tggaaagatt cagtcagacc cagaattaga agaacaattg
     8281 cgacggttaa aatttgatat tcgcaagaat ggtgtcaaag tcgctggcga tccatattta
     8341 atgaatgagg agacggatgc tcgaattgaa ataaatcaag taattgcaga atttgagcgg
     8401 attgcggacc aagcaaaaga accagatatt cgtcaatact tgttagaaat gaaagcagag
     8461 ttggaagtaa atggtattac agatgagtaa cctaaaccaa cacaactgac tgttaggcgc
     8521 tgaccgcgga ggattcgcga agcagaaatc ctccgtggtg ctgtgcctgt tcatggacgg
     8581 cgttagccga ccatgatgtc tcacccccgt atctaacagg ggggtacaaa aacacaaaaa
     8641 ataagtaagc aaccattaag aatgcttgtt gtatcaaaga tagtaagtaa tttgtatagg
     8701 tgttaactca tttgaaaaag ttaacacctt gaatttggag gtgagaactt ggcacaacgg
     8761 aatttagatt atcggctatt aaaagaccga cgcaacgaat acggcgtttc acaaaataaa
     8821 ttggctacgg cttgtggact tagtcggccg tacttaaatc agatagaaaa tggtggcgta
     8881 accgcatcta taaaaaccat gaggaaaatt tttgaccaac tggaaagctt taatcccgat
     8941 ttgcctttga cgttactgtt tgactatgta aggattcgct ttcccacaac ggatgcacga
     9001 aaaattattc aagaaattct ccatttgaaa tttgagtata tgctccatga agattatgcc
     9061 ttttactcct atcaagaaca gtatgtcatg ggtgatattg tggtgatgtt gtctcatgaa
     9121 gaagataaag gtgtgctttt agaattaaag gggcgaggtt gccgacaatt tgaaactttt
     9181 ttactcgctc aaaagcgtag ctggtacgac tttttcgagg attgtctaaa ggccggtggc
     9241 gtgatgaaac gcttggactt ggcaatcaat gatcgagtgg ggctattgga tatacctgag
     9301 ctaacgaaaa aatgtcagaa ggaagaatgt atctccttgt ttcgtacctt taaaagttat
     9361 cgttccgggg aacttttaaa ggctgatgaa aaggacggca tgggcaatac cttatatatc
     9421 ggcagtctca agagtgaggt ttatttctgt ttgtatgaaa aagactatga acaatatatc
     9481 aagttaggga ttccattaga ccaaactgag acgaaaaatc gttttgagat tcgactgaaa
     9541 aatgaccgtg cttttcatgc gattcaagat ttgttaaaag gtcgtagcat tgagagcacc
     9601 acgttttcca ttatcaatcg ttacttgcga tttgcggata aagtagaagg taaaaggcga
     9661 accaactggc ccttgaatga acaatggggg cgttttattg gacggaatcg gaaagagatt
     9721 caattaactt ccgagccaaa accgtatacc attgaacgaa ccttgaattg gctaggccga
     9781 caagtcgccc ctacgtggaa aatggctaag gagttggatc gattgaatcg gacaacctat
     9841 atccaggata tggtacagaa tgcacgctta tcagaccgac ataaaaagat tttggagcaa
     9901 caaagtatgg caattgaaaa tttgattata tgaaaagagg aatcgtcatg ggaattgtaa
     9961 aagatatttt tttggtattt ggtggcagta tgcttggtgt tactgtgatg tgcttgatga
    10021 atgcaagtgc agcagcggat cgagcaatgg aaaagaaagg aaagtgacaa gatgaatttc
    10081 ggacaaaatt t
//
LOCUS       DAFTHM010000094        10026 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFTHM010000094 DAFTHM010000000
VERSION     DAFTHM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.094"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..131)
                     /locus_tag="L7C88_002265"
     CDS             complement(<1..131)
                     /locus_tag="L7C88_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9559068.1"
                     /translation="MCANRYAKNKKAGGVCLVEYQVKKFEELSTAEFYAIVKERIAV"
     gene            complement(173..418)
                     /locus_tag="L7C88_002266"
     CDS             complement(173..418)
                     /locus_tag="L7C88_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBP9559069.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(534..1112)
                     /locus_tag="L7C88_002267"
     CDS             complement(534..1112)
                     /locus_tag="L7C88_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBP9559070.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1189..1719)
                     /locus_tag="L7C88_002268"
     CDS             complement(1189..1719)
                     /locus_tag="L7C88_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBP9559071.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1723..2583)
                     /gene="rlmB"
                     /locus_tag="L7C88_002269"
     CDS             complement(1723..2583)
                     /gene="rlmB"
                     /locus_tag="L7C88_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBP9559072.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2576..2971)
                     /locus_tag="L7C88_002270"
     CDS             complement(2576..2971)
                     /locus_tag="L7C88_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBP9559073.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2968..4380)
                     /locus_tag="L7C88_002271"
     CDS             complement(2968..4380)
                     /locus_tag="L7C88_002271"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBP9559074.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4377..4913)
                     /gene="cysE"
                     /locus_tag="L7C88_002272"
     CDS             complement(4377..4913)
                     /gene="cysE"
                     /locus_tag="L7C88_002272"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBP9559075.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4999..5238)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5235..6695)
                     /locus_tag="L7C88_002273"
     CDS             complement(5235..6695)
                     /locus_tag="L7C88_002273"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBP9559076.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6865..8022)
                     /locus_tag="L7C88_002274"
     CDS             complement(6865..8022)
                     /locus_tag="L7C88_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBP9559077.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(8056..9426)
                     /gene="radA"
                     /locus_tag="L7C88_002275"
     CDS             complement(8056..9426)
                     /gene="radA"
                     /locus_tag="L7C88_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBP9559078.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9489..10016)
                     /locus_tag="L7C88_002276"
     CDS             complement(9489..10016)
                     /locus_tag="L7C88_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBP9559079.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2554 a         2253 c         1806 g         3413 t
ORIGIN      
        1 aaaactgcga ttcgttcttt gacgatcgcg taaaactctg ctgttgacaa ttcttcaaat
       61 ttctttacct gatattccac taagcaaacg ccccctgctt ttttattctt agcataccga
      121 ttcgcacaca aaaaagcaaa cgaaccttac gaatctcagg ctcgtttgct ttttaaactg
      181 cttcagttaa aaattcgatc tcaactgtcc gagtaagtac atctgaatag ctgtaagata
      241 ctcgttcaaa agaattttct tcaggatcca aatcaacaac gaatactgaa ggataggttt
      301 ctgttaaaac gccgcggcgt tctgtttgac gctttcttcc tgtctgagca accaacatga
      361 ttgggctgcc gatacgacct tctaaatctt tcttgattga agctaaagtt gttggcatac
      421 agttcacctc tactatcaac tataccacat atttttaaaa ttttcaagtt taccataaaa
      481 aaaaaaagaa atgcaataaa aataaataag aagctcatta agatttttct aaattattcc
      541 tcattataaa atttcaagtg tttttttatt ttgagtttta ctctcccgta agcgctcatt
      601 acttgcttgt gatccattgc taaacattca gccatgtcta caaaatcaac gccttgcata
      661 taataatgaa aaattttagc ttctattttt gaaaactgga tttcgcaatt ttcgattgct
      721 tcttttaata aaagatgctg aattgctaaa ggttcttgca atgtgatctc tgctaaaaag
      781 tctggtcctt ctgtctctat tttttggtcg attgagactt catctttttg atcacgacgc
      841 ttcagcgcgt tctgcttcct caacagagaa tagatttgat tgcttataac gcttttataa
      901 taacttccaa agctaacacc tttgcttttt tcgtaagttc tcaatgcctg atataaagcg
      961 atccttgctt cttgttccca atcctcagaa acataatttc ttaaataata ggtgtttttc
     1021 aaacgtagta aaagtggaaa atatttttga tacagggcag caaatgcttc ttcgtcacca
     1081 ttacgtgcag cgcgcaataa ctcctcagac ataaaataat tcctccataa attcgtttat
     1141 ggaggaatct tatcatcaat gattcatcga actgattaga acgatatgtt atttattttt
     1201 tctcattaaa tcgtccaatt tttgggacaa tttttttaac tgctcttcat tccatggaga
     1261 attacgtcgg aaatcaataa aatgcatatc tttattttct tgggctattg ttttttccgt
     1321 tttttttatc gtcttatata attcataagc agaagttcgt aatgctcctt gggaaaagat
     1381 catccactgt tctgctaaat cgcttgtcgc cactgtcact tgtgtcaaac ggtcattcag
     1441 ctgaccagcg attctctcga tataactgtc agccgtttcg tcttctttcg taaaaacaac
     1501 atccaactgg tatttcttat aattttgttg gatgcccgga actagttggg catcgaagac
     1561 aacgatgact tccattcctt catatttcgc ataatttgat aaacgatgta aaagagcttc
     1621 tcttgcatcc gccattttgt cctgcttttt aagctggaca agttccggcc acgaaccaat
     1681 catgttgtag ccgtctacaa tcaacagctg ttttttcatg gtctactccc cctgacgttg
     1741 ggaaaaagcc tgatacataa gcaaaccagc agcaacactg gcatttaagc tctggacgtg
     1801 cccggtcatc gggatcgtca gcaattcatc catttctttt ttcaatcctg gactcattcc
     1861 tttgccttca ttaccaatga ctaaagcaat tgatcctttg gcattccatt tttggaagtt
     1921 tgtgccggtc atatctgtgc caaataccca aaatcctgtt tctttgagct gttgcacagc
     1981 ttgtaccaaa ttcgtcacgc gtgcaacagg gacatgttcg actgccccag tggaagtctt
     2041 tgttacgata ggtgtgattc caactgctcg gtgttttggt atgatcacac catcgacgcc
     2101 acttgcgtct gctgtccgta aaatcgaccc aaaattgtgt ggatcttcga tgctatccaa
     2161 aatcaaaaag aaggggtctt cttttttctc ttttgttcgt tcaatcagtt ggtcaaggga
     2221 taaatattca taaggtgtaa tcgcaagaac gactccttga tgcacgccgt gatcgctcaa
     2281 agtttctaat ttttgtttag gaacccattt gactggcaca gcttgttcac gtgcgatttc
     2341 tttcagttct tctacttttt ctcctcgtga atcttcttga agaaagagtt tattccctcg
     2401 cccttgttgt agcgcttcta ctgcggcatg gtgcccaaag acgaaattat cttctaatgc
     2461 ttcttcattt tgatcagaaa ctgactgatt tcgtccagtt tgctttttat ttgaatatct
     2521 attttgtttt ttgtcttcaa atccacgttt cgattgatgt ttgtttgttc tttctttacc
     2581 catttttttc accaactttc tgaatacacc agcggatcaa ttcttccatc cgctcggttt
     2641 gttttgtcaa atgcagatag cccatgagcg cttcgaaccc tgttgcgacc cgatacgtcg
     2701 taacatcagc attttttgcg ctcgtatggc ttttagcatt tcttcctctg cgataataaa
     2761 gttcttcttc ttctgtcaaa agatgttctt ccagcatttg ctgaatcaaa aaggcttgtg
     2821 cattcgcaga aacataattc gttgccgcac gatgcagctt attgggtttt gtttctcctt
     2881 gatcaatcag gtggtcacga acatagattt cgtaaatcgc atctccaaca taagccaagg
     2941 ctaaaccgtt caattgtgtg taatctctca tgcttctctt ctccatcggg ttccttgcgg
     3001 tgtatcttct aataagatcc ctttttcttt caacaaatca cgaatttcgt cgcttcggac
     3061 aaaatcacga ttgcttcttg cttgatttcg ttcttcgatc aattgttcaa tctcttcatc
     3121 taataactct tctgctgtaa ataaaatacc gaagatcgaa agccattgcg agaataaagc
     3181 ttctccttgt gccaagacag cggcagaaac tttcggctgg tctagataag tgttcagcca
     3241 cttagcaagc tcatagacca ctgtgatccc atttgctgca ttaaaatcat cgtccatttc
     3301 ttcgatgaat cgctgttcta aattttctaa caaagcgatt ttatccgcat catctgccaa
     3361 attctctgag gcagtttctt ggcggaattt caaattgtca aacgtattct tcagtcgttg
     3421 taaattggtg gctgcttctt tcatcgtcgt ttcactgtag cggatcggac gacggtattg
     3481 tgtggtcgcc atgaagaaac gcaagacttg tggatcaacg tttttgatca tttcatgtac
     3541 agtgatgaaa ttccctagag atttactcat tttttcatcg tcttcgccaa tcgttacata
     3601 gccattgtgc atccagtaat tagcgaattt tttccctgtt ttcgcttcac tttgtgcgat
     3661 ttcattttca tgatgaggaa attctaaatc ttgcccgcca ccatggatat cgatcgtttc
     3721 tcctaaatgt tttgttgcca taacggaaca ttcaatatgc caaccgggac gtcctttgcc
     3781 ccatggtgaa tcccaagaaa tctcgccagg ttttgcttgt ttccataaag cgaaatctaa
     3841 tgggtcttct ttttgctgct gttcttcccc tgtacgctga cttgctccga cttccagttc
     3901 atcgatggat tggtcactta atttcccata attttcaaat ttacgggtac ggtaatacac
     3961 atcacctgaa gattcataag catagccttt ttcaaccaac acttgaataa atgctaaaat
     4021 atctggcata tgatccatga ctcttggatg cagtgtagca ggttcgacat tcaacgcttt
     4081 cgtatcttct tcaaatgctc ggatgaaacg atcagcaact tctggtgctg taatacctaa
     4141 ttcgtttgct gtacggatga ttttatcgtc tacatccgtg aaattcgata cgaaatcgac
     4201 tttatagcct cgatattcaa aatagcgtcg aattgtatcg aaagcaatgg tgctacgagc
     4261 atttccgata tggatataat tatacacagt cggtccgcag acatacatac cgacatgtcc
     4321 cttttgtata gggatgaatt cttctttttt tctggtcaat gtattgtaga tttttatcat
     4381 tctgatctcc tcactttttc tcctttgatt cgaacgactt ttgctggtac tcctaccgct
     4441 gtagcgtcgt ctggaacatc tttcaacaca acggcacctg caccgatttt ggcgtttttt
     4501 ccgatcgtta ccggtcctaa tatctgcgca ttcgcagaga gcatggctcc ttgtttaaca
     4561 gttgggtgtc ttttacccgt ttcttttcct gtgccgccta atgttacgcc atggaataaa
     4621 atcacatcgt cctcgatttc tgcggtttcg ccaatgacga ttcccattcc atggtcgatg
     4681 aacacgccag ttccaatcgt tgctcctgga tggatctcaa caccagttag gaaacgccag
     4741 aattgagcat tgatcttcgc caataaaaag agccggtgct gatataaaaa atgagagaaa
     4801 cgatgccaaa acaaggcatg aaaaccaggg tatgtcaaaa cgatctcagc tgtcgaacgt
     4861 gcagccggat cgtttctctt tgctgcatca atcgctcggg taaaccaact catgactttc
     4921 cactcctttc gtaagaattt tatgtaggaa atcatcttct tataaagaaa agaagcgcct
     4981 tttaaataag tttccttatc aaaagacgct ttccgcgtgg ttccactttt cttcataatc
     5041 aatgattatc tctgacagct aacgcctgtt atacgttctt ggctactttg tttcctataa
     5101 aacagttttt cctgttttct gtgtttcgcc aagaccactc ccagaggcat ttcggcaacc
     5161 attcattgat accttgcacc acccggtatc tctcttgtaa tgatcagctg cttacttttt
     5221 tctgttcatc gtgtttagtt cagtacttga tttaaatgtg ctaatgattt ttcacgacca
     5281 agcaattcga tcgtttcagg caattctgga ccatgcattt gtcctgatac agctacacgg
     5341 attggcatga aaagattttt tccttttacg ccagtttctt tttgaacagc tttgatggca
     5401 gctttgacag ttggagcatc tactacttcc atttgttcta gctgtgcttt gaatgcgtgg
     5461 agaacagtag gaactgtttc accagcaagt acttcttttg ctgcttcatt caatacagga
     5521 tgttcattga aaaatagcgt agacagatca acgatttctg cagcatagct catttgaggt
     5581 tgatacaggc taacgatctt cttcacccat tcgattgtct tttcatctgg gttttctgct
     5641 acacgtccat cagcgattag ataaggcaga cacatgtcag taaatgcatc tagatccatt
     5701 gctttgatgt aatggttgtt tacccattgc agttttttcg catcgaaagc tgcgggtgat
     5761 ttacttaggc gttttggatc gaacattttg atcaattctt ggtgttcgaa gatttcgtct
     5821 tcgcccacag gtgaccagcc caataatgca ataaagttga acattgcatc tggtagatag
     5881 cctaattcgc gatattgttc gataaattgc aagattgatt cgtcacgttt gcttagtttt
     5941 ttacctgttt cactgttgat gatcaatgtc atatgtccga aggttggtgg tgtccagcca
     6001 aatgcttcat agatcatcag ttgttttggt gtattggcaa tatggtcatc tccacgtaaa
     6061 acgtgagtga ttttcatcaa atgatcatcg accgcaacag caaaattata agttggcata
     6121 ccatcgcgtt tttggatgac aaagtcgcca ccgatattat cggattcgaa cgaaatagcg
     6181 cctttcacca tatctgtaaa tgcgtattct gtattgcgag gcacacggaa acgtacaaca
     6241 gattctagac cttgtgcttc tttttctgct tgttcttcag gtgtcaagtt cgcacatgtt
     6301 cctgcgtaat gaggcatttc tcctcttgcg cgttgtgctt cccgttctgc ttctaattct
     6361 tcttctgtgc aatagcattt gtatgctcga ttgctagcaa gcagctgatc aatcagcggt
     6421 tgatagattt ctttacgttc agattgacgg taagggccgt attctccagg attttcagga
     6481 gattcatccc aattcattcc caaccaagca aggttttcca actggctttt ttcgccatct
     6541 tcgatattac gtttttggtc agtatcctca atacgaataa taaagtctcc atcattgtgg
     6601 cgggcaaaca aataattgaa taatgcagtt cttgcatttc caatatgcag gtgcccagtt
     6661 ggacttggtg catagcgtac gcgtactttc gtcattttct tcctcttctt tcaaactaga
     6721 ctttgactaa cagcaaaaat tccgtcagtt acggcttctc aaatatcatt tatttaaagc
     6781 cactcagcac aaattttacc ttttctaagg taaatagtaa agccaactgg ttgaatttcc
     6841 ttaccagttg gctgaatttc ttttttattt tgattgttta gtctttttct ctgtctcttt
     6901 tttattgtcg attcctcgtc ctgcatgtgc aggtttagca aagatcatgc gtccagcagc
     6961 tgtttgaagg gcacttgtta caacgacttc gatacgttca ttcatgtaat gctgtccatc
     7021 ttctacgaca accatcgtgc cgtcatcaag gtaggctact ccttgttggc gttctgtccc
     7081 ggcttttact actagaacat tcatcgtttc accagggatg acgactggtt ttacggcatt
     7141 tgccaacgca ttgatattaa gaacaggtac attttggaat tcagagactt tattcaagtt
     7201 atagtcattg gttacaatga caccatctaa aagcttagcc aatttgatca atttgctgtc
     7261 tacttcactg atatcttcaa agtctccatc gtacatttcg acagatatac cctcttcttt
     7321 ttgcaaggca tttaggatat ctaatccgcg acgaccacgc acacgtttca aactatcccc
     7381 tgagtccgcg atgtattgta gttcgtaaag aacaaaatta gggatcatca aggttccttc
     7441 taagaatcca gtctttgtaa tatcataaat ccgaccgtca atgatcacgc ttgtatccaa
     7501 gattttatat ttatggaaat tttctcctga ttttcgttct aacagttgac tctcaacttg
     7561 actagctgtt tcttgctcga tttttttgct tcgtgaacca aaaactttct tccattcttc
     7621 gattcgtgtc gttcccattc tcaatcccag atagcctaag atgatcatca gtaaaatcgg
     7681 caatacacta ttgacgaatg gaatttccat attgtaaaga ggggtcgaga tcacaacacc
     7741 taaagtcaat ccgatgatcg caccgatcgc accgaagaga agataagtca agctgacctc
     7801 acttagtttt tgttctactt gtttgataat agctgagata tgtttggcca acagcaaaga
     7861 taataaaaag aaaataagtg cgcctaacag gctgttggta aatgtattat tcagccatcc
     7921 gtttgactgt tgaccgattg cctgccaagc tgagggtaaa aatgaaatac ccaagcttgc
     7981 gccgacaatg atcatcagca aagtaatgac acgtttttgc atcgtttttc ctccgtttcg
     8041 acaatcattt attagttagc ggaacacacg cttcaacgtt tcagccaaag ttgctactcc
     8101 aactatctcg attccttttg gcgcttccca gttacctaag ttgtttttag gtaggtatac
     8161 ttttgtgaag ccgagttttt ggacttcttt gactcgttgt tcaatatgac tgacacgtct
     8221 gatttctcca gtcagtccaa tttcaccgat gaaacattcc gttggctgtg ttcctttttc
     8281 tttatagctt gaagcaatac tgacagcgat agctaaatca atcgctggtt catttaattt
     8341 taccccacct gcagctttta agtaagcatc ttgattctga agaagcaacc cagctctttt
     8401 ttccagcact gccatgatca gagatacccg attgaaatca agacctgttg ttgttcgttt
     8461 ggcatttccg aacatagtag gtgtgactaa tgcttggatc tctaccaaaa ttggacgtgt
     8521 cccttccatt gccacaacga tagcagagcc agttgcaccg tctaggcgtt cttctaagaa
     8581 aatctgtgaa ggattagcga cttcttccaa tccatgctca tgcatttcaa aaatcccaat
     8641 ctcattcgtt gagccaaatc ggttttttac tgctcgcaaa atccgaaaac tatgatgttg
     8701 ttcaccttca aaatataaca ccgtatccac catatgttct aacattcttg ggccggcgat
     8761 cgagccttct ttggtaacat gaccgacgat aaaaatggct atcccatttg ttttagcggt
     8821 tttgagtagt tctgcagtgg tttctcttac ttggctgaca cttcctgcca cacttgtgat
     8881 gtctggctgc gtcatcgttt ggatggaatc aatgataaca taatcagggg agatatgttc
     8941 gatggcacga ctgatttcgt tcatatctgt ttcagcgtat agataaaatt ctgtgttgat
     9001 acttccgagg cgttccgcgc gtaattttat ctgctctgcg ctttcttcgc cggatacata
     9061 taagactttt ccgcctatgg ctgctaattg ctgagaaact tgtaacagca aagtggattt
     9121 cccgatacct ggatcgccac caatcaagac catagaccct ggcaccacac ctccgcctaa
     9181 cacacggttc agttcttcta attttgtttt gatccgaggt tcttttttag ggacgacgtc
     9241 tgcgattttt gttggttttg ctttttctcc tgtcaaactt gtccgagttc tgcggtccgt
     9301 tgtatcttgt tcgatttctt cgaccatcgt attccatttt ccgcaatttg ggcagcgtcc
     9361 caagaactta ggcgacacat acccgcaatt ttggcaaaca aattgtactt ttgatttttt
     9421 tgccattgta ccgcctcctt ttatcctaat catgagacat taaatcaagc ttaagtatct
     9481 ttaacgtttt atttactgga agaaccaaat ccgccttgac gttgagcagt cgtttgatct
     9541 tgatctgctt ttaaaaacgg caaaaagatc ccttggccga tacgctcgcc ttttttgatc
     9601 actacatcct tgaaaccaaa gttggtgaat tggaacatga tatggccttc atttgcctca
     9661 ttattgtaat aatcactgtc aatcacacct actccgtttg tcaacactaa aaaccgcttc
     9721 aacggattgc ttgaacggtt agcaagctgc aaaaattcat cttctcccat gtaagctttg
     9781 attccagtag gcacgagggt tggtttcaat tgtttttcat tttctgatac atcttttttc
     9841 aatccatctg cgactgtttc caaccccttt ttccagcctg ctttccagat acttggaatc
     9901 acgacctctt ctgctgcttc aaaatcatag ccagcagcat gatgtgtagc gcgctgcggt
     9961 agattgatat tttgatcttt atatttagaa ataacttcaa atcctctttt tctcaccggt
    10021 tttcct
//
LOCUS       DAFTHM010000095         9623 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFTHM010000095 DAFTHM010000000
VERSION     DAFTHM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.095"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            28..3045
                     /locus_tag="L7C88_002277"
     CDS             28..3045
                     /locus_tag="L7C88_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBP9559080.1"
                     /translation="MFKRMATWLAIFVTFLNPMLGSVTAFAETINESNSTEEVMKTEE
                     SKSSEEAISTETTSETTEETTTQDTTEDVSPPNVMTQEVPEGYEKYFITIEDIQKATS
                     FSEQERLAQESEEWQAILEKNAQTRATNLTLTENGRKDVNMTRITPEGTMYTHDYMVR
                     WQIDGEDVFCIQEGAITSAGIQYDVTPLENLITTSAIRKKISLIGYFGYYSSGSMDNY
                     VLAQTYIWEVLGGSFVNYGTIGQSNYEAFKQTVDRKINNLLEDPSFDSQTVTVKVGEE
                     VEVKDTKGVFSQWDGSVVENTANVQVRKSGNSLFIKANQNSNDGRISVSSLDPNSRGV
                     GSSFAYVDPVAQNLGKLYVPDPNRAGLTIKVLKNGDFKLTKLDAVTGKKVPNVTYEIK
                     RHDTGETKQYTTDAKGEIALKEIPAFYEKDGKYVQNKLDVKEVKAPAGYILDKQTHTI
                     TIEPNKEVTLTAKNDLQQFIPEGKKVKEVYNAEESWNQGKPVYDTVPAENIEFDIIAK
                     TDITAPDKETVLVKKGEVLDSVKTDKDGHWKANKKFYNGDQNKYQLIEKNVPDNYRQP
                     SEEQTTFSVAYGDNTTPVLTFELDVIDNLLKTGEVDFNKVDSINHLQLPGAKFLIEGM
                     TAHNKNVSFVYETKEEPEKLKLPDGTYKFTEIVFPEHYGQASGQTETILVTVKDGEVQ
                     PITVKNEEIVVPEEDQPEISTLFVTTTGGKDFNPKKDQELVDKVSQVFPKSAVGTEKY
                     WVTQFHKITADGKVTVLDTVKETRKVTDEKETFDVTFNYKADMVSDGDTIVATHIVYN
                     DKEEEEEFARHFDLTNKDQTVTAKEPKIETRFITVNGDQTFDPDKDQELIDHVSQEFP
                     ESTVGETKYWVTQFHKIDKNGKDTVVGTVETARKVSKASEEFKVSFDYKAGTLKDGEK
                     LVATHIVYKDKDHKEEEARHFDLKNEKQTLTAKGIKKETPTTPVKQTPTSTPKQSLPK
                     TGETVNDVLIALGLFLFVGVGAVLVRRKMKQSN"
     gene            3109..4572
                     /locus_tag="L7C88_002278"
     CDS             3109..4572
                     /locus_tag="L7C88_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBP9559081.1"
                     /translation="MKKTSKCLSALLLVGQVFGYTPAVLANEQGNNQLTNSQSATITE
                     ETTTNSTGEENQPETPTEDTIDTPDNPEMNAPPTGSEEQPETPNQPDKPEDNQQPEEE
                     PSEEPNEQPSDESSQTPQKPSTETEAEPPTKTERPQKAPEQSVTVPMNDVPQAQSIGS
                     EETKNYHQAPSAPIQELVPSSTQDNEGTIHFEKDASVETFIRKIGESARKIGQENDLY
                     ASVMIAQAILESASGQSQLAQAPNYNLFGIKGTHNGKGVSFATQEDLGNGTLYTTQAT
                     FRQYESYEESLKDYAKLLKEGLVGNTSFYDGVWKSKAKTYQEATKFLTGRYATDTSYD
                     KKLNGLIETYDLIKYDKEVAGPQLSKEGYMVPLKNYSISSSFGWRGEEFHRGLDMAAN
                     QGEPIYASKAGTVIEASYHTLSGNYVTIEHEDGSVALYAHQQEYCVNVGQTVEQGQII
                     GYVGSTGNSTGPHLHLELALDGSLTKDKLINPETVLF"
     gene            5039..5419
                     /locus_tag="L7C88_002279"
     CDS             5039..5419
                     /locus_tag="L7C88_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HBP9559082.1"
                     /translation="MITNYKKFWQNSFNYKGKATRKEYWLVALMNALIGFGLGLAIGL
                     AGALNASETIIGCLIGVLIVYCFVVLVPSLSLSVRRLRDAGFHWAFIFFYFVPTIGSL
                     VLLVLYCLPTKESIEDKQVQEETR"
     gene            5416..5685
                     /locus_tag="L7C88_002280"
     CDS             5416..5685
                     /locus_tag="L7C88_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559083.1"
                     /translation="MIIVTGIVLLGIGVLFGYHFAYFPKIGEWQQRQAIQKYFQVKGN
                     EYTYYAEDEDSYIVSLNNQEYRVKFSLNNPIQVVYAVEVVEEVFD"
     gene            5685..6605
                     /locus_tag="L7C88_002281"
     CDS             5685..6605
                     /locus_tag="L7C88_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559084.1"
                     /translation="MMMIRFTEVDNMSLLTDKKIALDKAFIQLKRENEELLARAEIGW
                     CTLEIYTENHEIPVFEGSYDFPVEEFHLISLIEQSLTENGQLSEEAQTFIQTLNSELP
                     KFYQVKKDQKNERRPTKIKKEKKTPLSVETAFTQSNGSLQKKKMSFQWLLFGFIVVVS
                     CGLFIMQLSTQREIEQLTKKEHQLQERIAFAEELATKQPQIDTFSRYFITNYYSGEMA
                     EERYRKKLQSFLTEKVAKQISPQKEKVKSILSWEMKKEGKHWQIAYVITLETEKKTQE
                     TKKVSFQLEEQEKNYLVSTLPELDDFEINQ"
     gene            6627..7499
                     /locus_tag="L7C88_002282"
     CDS             6627..7499
                     /locus_tag="L7C88_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBP9559085.1"
                     /translation="MKKMILGSLFSATVLLGMVGTSAYADTTSPGDPSVPPTEIIPPT
                     EETPEVPEEPVLPPTDGGEETPEIPEIPETPETPEIPPTEENPDTGGGTETPEVPENP
                     DTGGGEGTPEVPPVEENPGNGGNTETPEKPSNPGGNEGNTTPPTTPPTNNGGTNTTPP
                     VQDVVVKPDGSIGSQQTGGQNVQIETNNASELTHIPTPSTPIETASGEKIVSVVDGVA
                     YKESGNGLTPISDKVEQLPSGNIAVKGSDGKMKVLPKTGEEVSLVATALGGLLASGSG
                     FAFWRKRKATQKMN"
     gene            7518..8690
                     /locus_tag="L7C88_002283"
     CDS             7518..8690
                     /locus_tag="L7C88_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBP9559086.1"
                     /translation="MKKKLLLWCGFGCLPTLLLCMFGFLFMILLISSGSEEEEIDCSP
                     TEIVASTISLTNQGMETNGLQIAKEVQKHIPNTTLEGLAGMLGNFQQESSMSPTAIER
                     PNDPLSGHGIAQWTAGRTTALKNFAKERNKEWSDLGVQVEFLIHELNTTEKASQVALQ
                     AKSVEEATEQWQVKFERAGIPMMGNRITFANQWYAKLGKNDSDPVASITLENGANAGS
                     KDLTDYCLETTGTSSSSDSNVLNVAKSLIGYFHYSQPQRAQFGSVENPDKNGYADCSS
                     FVWLVLTKAGYKTPANVGWFTGSMTSDARGSKQYLQEIPESEAKAGDIIIVNLGSGVG
                     NDGHTAVLAEDWHGLSTKVIEQGGMNTNGVGEGQVNLSFGYLLNGGDICFARPIKK"
     gene            8701..9351
                     /locus_tag="L7C88_002284"
     CDS             8701..9351
                     /locus_tag="L7C88_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559087.1"
                     /translation="MKKRFIYVCVGGLFLFGVGSTFFLIHEKLQLTAKEEKLTVEINK
                     FQEEKKGQEDLVTSLKEQLQQVESEVTTLKKANEELKNNDSTEKGNIQTFQKTVTEAF
                     EVLFNYEPDSFQERKNNCAPYLSDKLMKQYFKEGVSYGDSNGVSSELEKCSVYLKSTQ
                     KATIQGLVVVSYRNKIGDSSWNNAMNIFDVTFDPASKKITFMQNLGSSFNQQLLEE"
     gene            9367..>9623
                     /locus_tag="L7C88_002285"
     CDS             9367..>9623
                     /locus_tag="L7C88_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559088.1"
                     /translation="MERQESIREVQEVPTEQAKETQEGRSFSYGKNFSFLRPSIQISV
                     FVLWRIHNNRYSVGSQLFYQEICHALSKKYSQNAYKEALAF"
BASE COUNT         3530 a         1630 c         2028 g         2435 t
ORIGIN      
        1 aaataaaatg aaaggaacga aaaaaatatg tttaaaagaa tggcaacttg gttggcaatt
       61 ttcgttacat ttctcaatcc catgttagga tctgtaacgg catttgcaga aacgataaat
      121 gaatcaaatt ctactgaaga agtaatgaag actgaagaat caaaaagtag tgaagaagcg
      181 atcagtactg aaaccacaag tgaaacaaca gaagagacaa ctacgcagga cacgacagaa
      241 gatgtttctc cgcccaatgt aatgactcaa gaggtccctg aaggttatga gaaatacttt
      301 ataaccattg aagatattca aaaagcgact tctttttctg aacaagaacg attggcgcaa
      361 gaatctgaag aatggcaagc aatcttggaa aagaatgcac agacacgtgc taccaatcta
      421 acattgactg aaaatggtcg taaagatgtg aatatgactc gaattactcc tgaaggaaca
      481 atgtatactc atgattacat ggttcgctgg caaattgacg gagaagatgt tttttgcatt
      541 caagaaggcg caatcacgag tgcgggtatt caatatgatg tgacaccact cgaaaattta
      601 attacgacaa gtgctattag aaaaaagatt tctttaattg gttattttgg ctactattct
      661 agtggttcaa tggataacta tgtattagca caaacatata tttgggaagt tttaggtggt
      721 tcatttgtta attatggaac tattggacaa tctaattatg aagctttcaa acagactgta
      781 gatagaaaaa taaacaattt acttgaagat ccttcttttg atagccaaac agtgacggtt
      841 aaagtagggg aagaagtaga agttaaggat acaaaaggtg tgttttctca atgggatggg
      901 tcggttgttg aaaacacagc taacgttcaa gtaagaaaat caggaaatag tttgtttata
      961 aaagcaaatc aaaactcaaa tgacggacga atttctgttt cttcactgga tccaaattct
     1021 agaggggtag gttcaagttt tgcctatgta gatcctgttg ctcaaaatct aggaaagctt
     1081 tatgtgccag atcctaatag agctggacta actattaaag ttctaaaaaa tggcgacttc
     1141 aaactaacca aactagacgc tgtcacaggg aaaaaagttc caaatgtgac gtatgaaatc
     1201 aaacgtcatg atacgggaga aacaaaacaa tatacaacgg atgccaaagg ggaaatcgcc
     1261 ttaaaagaaa tccctgcatt ctatgaaaaa gacggaaaat atgttcaaaa taaattggat
     1321 gtcaaagaag tcaaagcacc agctgggtat attctagaca aacaaactca tacgattacg
     1381 attgaaccaa acaaagaagt gacgttaact gcaaaaaatg acttacaaca gttcattcca
     1441 gaaggaaaga aagtcaaaga agtctataat gcggaagaat cctggaatca aggcaaacct
     1501 gtttatgata ccgttcctgc agaaaatatc gaatttgata ttatcgccaa aacagatatt
     1561 actgcgccag ataaagaaac agtccttgtg aaaaaaggag aagtcttgga ttcagtaaaa
     1621 actgacaaag acggacactg gaaggcaaac aaaaaattct acaatggcga tcaaaacaaa
     1681 taccaattga ttgaaaaaaa tgtgccagac aactaccgtc aaccttctga agaacaaacc
     1741 acgttctctg tggcctatgg cgataacacg acgcctgtgc ttacgtttga attagatgtg
     1801 attgacaact tgttaaaaac gggtgaagta gacttcaata aagtcgattc aatcaatcat
     1861 ctacaattac caggagcgaa attcctgatt gaaggtatga ctgcacataa taaaaatgtg
     1921 tcctttgtgt atgaaacaaa agaagaacca gaaaaactaa aattaccaga cggtacgtat
     1981 aaatttacgg aaattgtgtt ccctgagcat tatgggcaag cgtcaggaca aacagaaacg
     2041 attttagtaa cggtcaaaga cggagaagta caaccaatta ctgtgaaaaa cgaagaaatc
     2101 gtggttccag aagaagacca accagaaatt tctactttgt ttgtgacaac gacaggtgga
     2161 aaagatttca acccgaaaaa agaccaagaa ttagtggata aagtgtccca agtattccct
     2221 aaatctgcgg ttgggacaga gaaatattgg gtgacgcaat tccataaaat tactgccgat
     2281 ggaaaagtca ctgtattaga tacggtaaaa gaaacacgaa aagtgaccga tgaaaaagaa
     2341 acatttgatg tgacgttcaa ctacaaagca gacatggttt cagacggtga cacgattgtc
     2401 gcaacgcaca ttgtctataa cgacaaagaa gaggaagaag aattcgctcg tcattttgat
     2461 ttaaccaata aagatcaaac agtgactgcg aaagaaccaa aaatcgaaac acgctttatt
     2521 acagtgaatg gcgaccaaac atttgatcca gacaaagacc aagagttgat cgatcatgta
     2581 tcgcaagaat ttccagaatc tacggtaggg gaaaccaaat actgggtgac tcaattccat
     2641 aagattgata aaaatggaaa agatacagtc gttggtacgg tagaaactgc acgtaaagtt
     2701 tctaaagcgt ctgaagagtt taaagtatcc tttgactaca aagcaggcac gttaaaagac
     2761 ggggagaaat tggtcgcaac tcatattgtc tataaggata aagaccataa agaggaagaa
     2821 gcacgtcact ttgatttgaa gaatgaaaaa caaacattga cagcaaaagg cattaaaaaa
     2881 gaaacgccga caacccctgt caaacaaacg ccgacgagca caccaaaaca aagcttacca
     2941 aaaacaggag aaacagtgaa cgatgtgtta attgcattgg gactgtttct ttttgttggt
     3001 gtgggggctg ttctggttcg tcgtaaaatg aaacaaagca attaaagtat gactagagac
     3061 agcaatcagc tgtctctaga tgattgattg aagaatggag gcaatcttgt gaaaaaaacg
     3121 agtaaatgtt tatctgcttt gttattagta ggtcaagtat ttgggtatac gccagcggtt
     3181 ttggctaatg aacaaggcaa caatcaactg acaaattcgc aatctgcaac gatcactgaa
     3241 gaaacgacaa caaattccac tggagaagaa aatcaaccag aaacaccgac tgaagataca
     3301 atagatacac cagataatcc agaaatgaac gctccaccaa caggttctga agaacaacca
     3361 gaaacaccga atcaaccaga caaaccagaa gacaatcaac aacctgagga ggaaccgtca
     3421 gaagaaccaa atgagcaacc ttctgatgaa agctcacaga ctcctcaaaa accaagtacc
     3481 gaaacagaag cggaaccgcc aacaaaaacg gaacgcccac aaaaggcacc tgaacagagt
     3541 gtgactgtac ctatgaatga cgtaccgcag gcacaatcaa tcggttcaga agagacaaaa
     3601 aactaccacc aagcaccaag cgcaccgata caagaattag tcccttccag cacacaagat
     3661 aacgaaggga ctattcattt tgaaaaagac gcgtctgtag aaacgtttat ccgtaaaatc
     3721 ggtgaatctg ctcgtaaaat tggacaagaa aatgatttat acgcttctgt tatgatcgcg
     3781 caagccattt tagaatccgc aagcggacaa agtcaattgg ctcaggcacc aaactacaat
     3841 ctatttggaa tcaaaggcac acataacgga aagggcgtct cttttgcgac acaagaagat
     3901 ttaggcaatg ggacacttta tacgacccaa gcaacttttc ggcaatatga gagctatgaa
     3961 gaaagcttaa aagactatgc caaactgtta aaagaaggct tagttggaaa tacctctttt
     4021 tatgatggtg tttggaaaag taaggcaaaa acctatcagg aagcgactaa atttttaaca
     4081 ggaagatacg caacagacac tagctacgat aaaaaattaa atgggttaat cgaaacctat
     4141 gacttaatca aatatgataa agaagtagct ggtccacaac taagcaaaga aggctatatg
     4201 gtacctctaa aaaattattc aatttctagt tccttcggtt ggcgaggaga agaatttcat
     4261 agaggattag acatggcagc caatcaagga gaaccaatct atgcgagcaa ggcaggaacg
     4321 gtcatagaag cttcgtatca tactttgtca ggaaattatg tcacaattga gcatgaagac
     4381 ggaagtgtgg ctctttatgc gcaccaacag gaatattgcg tgaacgtagg acaaacagtt
     4441 gaacaaggac aaattattgg ttatgtgggt tcaacaggaa atagtacagg accacattta
     4501 catttagaac ttgccttaga tggtagttta acaaaagaca aattaatcaa cccagaaaca
     4561 gtcttattct aaagaataag gctgtttctg ataaggagtg gtatagaaaa tgtggttact
     4621 ttttaaatat ttgatatatt tgtatctctc attttcgttt tttaatttga aatctcgtat
     4681 ctatctagaa cgtagtttat taaatatagt attaggaata ttttttatcg tttgggtctt
     4741 cattgactta tttctttact caaacgattt ttattttatt tataaagaat ttaaaaatca
     4801 gtaattgctt ggagagttaa catatattgc ataaaaaggc aaagtatgta catggtattt
     4861 atcgtgttca tactttgcct ttttatggcg aaatttttta gaaaggagga aaaaattttg
     4921 ttatttgtaa gtggatttct agctggtggt gtattggcca ccttttttat ggcaagtttc
     4981 attgttagta aaacagaaga aactagaatc aaaaataaac attagaaagg acaaagatat
     5041 gatcacaaat tataaaaaat tttggcagaa tagctttaat tacaaaggga aagccacaag
     5101 aaaagagtat tggctcgttg cgttaatgaa tgccctcatt gggtttggcc taggcttagc
     5161 gattggacta gcaggagcgt tgaatgcttc tgaaacaata attggttgtt tgataggcgt
     5221 attgattgtg tattgtttcg tagttcttgt cccgtctctt tctctcagcg ttcgacgttt
     5281 acgagacgca ggttttcatt gggcatttat ttttttctat tttgtcccaa cgattggctc
     5341 tcttgtgtta ctggttcttt attgcttacc gacaaaagag tcaatagaag ataaacaggt
     5401 acaggaggaa accagatgat tatagtaaca ggaattgttt tattagggat aggcgtttta
     5461 tttggctatc atttcgccta ttttccaaag attggcgaat ggcaacaaag acaagcgatc
     5521 caaaaatatt ttcaagtcaa aggcaacgaa tatacctatt atgctgaaga tgaggatagc
     5581 tatatcgtca gtttgaacaa tcaagaatat cgggtgaaat tttctttaaa taaccctatt
     5641 caagtggtgt atgcggtaga agtggtggaa gaagtgtttg actaatgatg atgattcgat
     5701 ttacagaagt tgataacatg tctttactaa cagataaaaa aattgcatta gataaggcat
     5761 ttattcaatt gaaaagagaa aatgaagagc tattggcacg agcggaaatt ggctggtgta
     5821 ccttggaaat ctacacagaa aaccatgaaa ttccagtatt tgaaggctcg tatgattttc
     5881 cagtagaaga gtttcatttg atttcattga ttgaacaatc tttaacagaa aatgggcaat
     5941 taagtgaaga agcacaaacc tttattcaaa ccttaaattc cgaattaccg aagttttatc
     6001 aagtaaagaa agaccaaaag aacgaacgtc gaccaacaaa aatcaaaaag gaaaagaaaa
     6061 caccactttc tgtagaaaca gcgtttacac aaagcaacgg ctctcttcag aagaaaaaaa
     6121 tgtcttttca atggcttttg tttggattta tcgtcgttgt atcttgtggt ctttttatta
     6181 tgcaactttc aacgcaaaga gagattgaac aactaacgaa aaaggagcac cagttacaag
     6241 aacgcattgc atttgcggaa gaacttgcga caaaacaacc acaaattgat acatttagtc
     6301 gttattttat tacgaattat tattcgggtg aaatggcaga agaacggtat aggaaaaagc
     6361 ttcaatcgtt tctaacggaa aaagttgcga aacaaatcag tcctcaaaag gaaaaagtca
     6421 aaagtatttt atcctgggaa atgaagaaag aaggcaagca ttggcaaatt gcgtatgtca
     6481 ttacattgga aaccgagaaa aagacacaag aaacaaaaaa agtgtctttt caattggaag
     6541 aacaggaaaa aaattatcta gtttccacgc ttcccgaact agatgatttt gaaataaatc
     6601 aataaataag agaagaggaa aaacacatga aaaaaatgat tttaggaagt ttatttagtg
     6661 caactgtatt gctaggtatg gtaggaacca gtgcgtatgc agatactacg tcaccaggtg
     6721 atccaagtgt accaccgaca gaaattattc caccaacgga agaaacacct gaagttcctg
     6781 aagaacctgt tttaccacca acagatggag gagaagaaac cccagaaatt cccgaaatac
     6841 cagaaactcc tgaaacccca gagattccac caacggaaga aaatccagat acaggtggag
     6901 gcacagaaac gcctgaagta ccagaaaatc cagatactgg cggaggggaa ggaacacctg
     6961 aagttccacc cgttgaggaa aacccaggaa atggtggtaa tacagagaca ccagaaaagc
     7021 cgtcgaatcc aggaggcaat gaaggaaata cgactcctcc aacgacacca cctaccaata
     7081 atggggggac gaacactacg cctccagtac aggacgtcgt agtaaaacca gatggaagta
     7141 ttggcagcca acaaacaggt ggacaaaatg ttcaaattga aaccaataat gcgtctgaat
     7201 taacccatat tccaacacca agtacaccaa ttgaaacagc ttcaggagaa aaaattgtct
     7261 ccgtcgttga tggtgtcgct tataaagaat caggaaatgg cttgacgccc atttcagaca
     7321 aggtcgaaca acttccaagc ggaaatattg cggtgaaagg gtctgatgga aaaatgaaag
     7381 tattgcctaa gactggcgaa gaagtgtctc tcgttgcgac agcacttggt ggattattgg
     7441 cttcaggaag cggttttgct ttttggcgca aaagaaaagc aacacaaaaa atgaactaag
     7501 cgaatgaagg atcaaacatg aagaaaaaac ttcttttatg gtgtgggttc ggttgtctac
     7561 ccacactatt actatgtatg tttggttttc tgtttatgat acttttgatt agtagtggtt
     7621 ctgaagagga agaaatcgac tgtagtccaa ccgaaattgt cgcaagtact atctcattaa
     7681 cgaaccaagg catggagaca aacgggcttc aaattgcaaa ggaagtacaa aaacatattc
     7741 caaatacgac attagagggt ctagcgggta tgttaggcaa ttttcaacaa gagtcgagta
     7801 tgagtcccac agcgattgaa cgaccaaacg atccattatc tgggcatggg attgcacaat
     7861 ggacggcagg gcgaacgact gctttgaaaa attttgccaa agagcgaaac aaagagtggt
     7921 cagatttagg tgtacaagtt gagtttttga ttcatgaact aaacacaaca gaaaaagctt
     7981 cacaagttgc attacaagca aaaagcgtag aggaagcaac agaacagtgg caagtgaaat
     8041 ttgagcgtgc agggatacca atgatgggga atcgtattac ttttgcgaat caatggtacg
     8101 caaaactagg aaagaatgac agtgatcccg tcgcttcaat tacattagaa aatggggcaa
     8161 acgcaggaag taaagacttg accgattatt gtctagaaac aacaggaaca agcagttctt
     8221 ccgatagtaa tgtattaaac gtagcaaaaa gtctgattgg ttattttcat tattcacaac
     8281 cgcaacgggc acaatttggt agtgtcgaaa atccagataa aaatggctat gccgattgtt
     8341 cgagctttgt gtggcttgtt ttaacgaaag cagggtataa aacgcctgcg aacgttgggt
     8401 ggtttaccgg ctcaatgacg agcgacgcaa gaggaagtaa gcaatactta caagaaatac
     8461 ctgagagcga ggcaaaagct ggcgatatta tcattgtgaa cttaggttct ggtgtgggaa
     8521 atgatggaca cacagctgtt ttagcggaag attggcatgg actttctacg aaagtaatcg
     8581 aacaaggggg aatgaatact aacggtgtag gtgaagggca agtcaattta tcctttgggt
     8641 atttgcttaa tggtggtgat atttgttttg ctcgaccgat aaagaaataa gaggtgtcaa
     8701 atgaagaaac gatttattta tgtttgtgta ggcggattgt tcttatttgg tgtaggcagt
     8761 acattttttc ttattcatga aaagctacag ctaacagcaa aggaagagaa actgacggtg
     8821 gagataaaca agttccaaga agagaagaaa ggacaggaag accttgtaac gtcactcaaa
     8881 gaacaacttc aacaagtaga aagcgaggtc acgacgttaa aaaaagcaaa tgaagaattg
     8941 aaaaacaatg attcaacaga aaaaggaaac attcaaacct ttcaaaaaac agtgacagaa
     9001 gcgttcgagg ttctgtttaa ttatgagcct gattcttttc aagaacgaaa aaacaattgt
     9061 gcaccatatc tttctgacaa actgatgaag caatatttca aagaaggcgt ttcctatggt
     9121 gattcaaacg gggtgtcttc tgaattagag aaatgttctg tttatttaaa aagcacacaa
     9181 aaagcgacta tccaagggct cgttgtggtg tcgtatcgca ataaaattgg tgatagttcc
     9241 tggaataatg ccatgaatat ttttgacgta acctttgatc cagcgtcaaa gaaaatcacg
     9301 tttatgcaaa atttgggaag tagctttaat caacagcttt tagaagaata agaaaaggag
     9361 aaggttatgg agagacaaga atcaataaga gaggtacaag aagtaccaac agaacaagca
     9421 aaagaaaccc aagaaggacg ttctttttct tatggaaaga atttttcttt tttacgcccg
     9481 tcgattcaaa tcagtgtgtt cgttttgtgg cggatacaca ataatcggta ttcggtaggc
     9541 agtcaactat tttatcaaga aatttgtcat gctttatcaa aaaaatacag tcaaaatgcc
     9601 tacaaagaag cacttgcctt ttt
//
LOCUS       DAFTHM010000096         9609 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFTHM010000096 DAFTHM010000000
VERSION     DAFTHM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.096"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            416..1525
                     /gene="pdhA"
                     /locus_tag="L7C88_002286"
     CDS             416..1525
                     /gene="pdhA"
                     /locus_tag="L7C88_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBP9559089.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            1528..2505
                     /locus_tag="L7C88_002287"
     CDS             1528..2505
                     /locus_tag="L7C88_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBP9559090.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            2530..4173
                     /locus_tag="L7C88_002288"
     CDS             2530..4173
                     /locus_tag="L7C88_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBP9559091.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            4181..5587
                     /gene="lpdA"
                     /locus_tag="L7C88_002289"
     CDS             4181..5587
                     /gene="lpdA"
                     /locus_tag="L7C88_002289"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBP9559092.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            5749..6024
                     /locus_tag="L7C88_002290"
     CDS             5749..6024
                     /locus_tag="L7C88_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBP9559093.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            6030..6797
                     /locus_tag="L7C88_002291"
     CDS             6030..6797
                     /locus_tag="L7C88_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBP9559094.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            6965..8794
                     /gene="typA"
                     /locus_tag="L7C88_002292"
     CDS             6965..8794
                     /gene="typA"
                     /locus_tag="L7C88_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBP9559095.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            9055..>9609
                     /locus_tag="L7C88_002293"
     CDS             9055..>9609
                     /locus_tag="L7C88_002293"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RecQ family ATP-dependent DNA helicase"
                     /protein_id="HBP9559096.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLL"
BASE COUNT         3246 a         1732 c         2118 g         2513 t
ORIGIN      
        1 atttcaagct gtttcttttt tttcggaaaa agaatacgat ataaagaaac taagaaaaaa
       61 ccattatttg tacgtccgtt cacgatgtgt aaataaaata aatgtttgca acaaaactgt
      121 ataacaccaa cgtttttaaa tagaaacaga tggttgtaag tttgattaga aaatagaaaa
      181 aatgcagatg aaaaataaaa cgctttcctt attgtgattt tattcactaa tgctgttaat
      241 atgcggattg gcataatttc ctttcatcgt gaaaatttgt gcttttagct tgtatttctc
      301 ataaatccat gataatttat taatgaagac ggttaaatag tgatacagtt ttattcactg
      361 tttcaatcgc agaatgaaga gattttctta tagatgagag aggaatgtgt gacaaatggc
      421 aaacaaaaaa gcaccgatcg acttccaagc actgctagat gaagtcaatg cagatttccc
      481 agtatatcaa gcacttgatc aagatggaaa cgtagttaac aaagatttag tacctgattt
      541 atccgatgat gaactcgttg aattaatgac tcatatggta tggtctcgtg tattagacca
      601 acgttcaaca gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa ctgctggaca
      661 agaggcaagt cagctggcta gtgcttacgc atttgataaa gaagatgttc ttcttccagg
      721 ttatcgggat gtacctcaac tagtaaaaca tggtttacct ttatctcaag cttttttatg
      781 gtctcgagga catgctgcag gtaattctta tccggaagaa ttgaaagctc taccaccaca
      841 aattatcatc ggtgcacaat atgtacaagc agccggtgtt gcattaggtt tgaagaaacg
      901 aaacaagaaa aatgtcgtct tcacttatac tggtgatggc ggttcatcac aaggtgattt
      961 ttacgaagca atcaatttcg ctggcgctta ccatgcaaat gccgtatttt atatccaaaa
     1021 caacgggtat gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa cacttgcaca
     1081 aaaagctgtc gcagctggga ttcctggtat tcaagtcgat ggaatggatc cgcttgcagt
     1141 atatactgta tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac cagtcctaat
     1201 cgaaacactg acttatcgtt atggaccaca tacactatct ggtgacgatc caacccgcta
     1261 ccgtacaaaa gacacagatg acgattggca gaaaaaagat ccattgatcc gcttccgtaa
     1321 atatttgacg gaaaaaggac tttggtctga agaaaaagaa gaacaagtca tcgaagcaac
     1381 taaagaagaa atcaaagcag ctattgctga agccgacaaa gtaccaaaac aaaaggtttc
     1441 agatttcttg aaaaacatgt tcgaagtatc tccacaatca atcaaagaac aaattgcaat
     1501 ttatgaagcg aaggagtcga aataatcatg gcacaaaaaa caatgatcca agcaatcaca
     1561 gatgccttag cacttgaact agaaaatgac gagaatgtcg ttgtttttgg tgaagatgtt
     1621 gggaaaaacg gaggagtttt ccgggcaact gaaggattgc aggaaaagtt cggagaagac
     1681 cgagtattcg atactccttt agctgaatct ggaatcgcag gattgagttt cggtcttgcg
     1741 ttagaaggat ttcgtccagt tcctgaaatc caattctttg gttttatttt cgaagcaatg
     1801 gacgaagtag tagctcaaat ggctcgtaca agatatcgaa tgagcggcac tagaaatcta
     1861 cccatcacaa ttcgttcgcc atttggtggc ggtgttcata caccagaatt gcattcggat
     1921 aatttagaag gtttgatcgc tcagtctcct ggtattcgag tagtgattcc ttccaaccct
     1981 tatgatgcaa aaggactatt gatttcttct attagaagta acgatccggt tgttttccta
     2041 gaacacatga aactatatcg ctcattccga gaagaagtgc cggatgaagc ttacgaagtt
     2101 cctttggata aagcagcagt tactcgtgag ggaacagatg tatctattat cacatacgga
     2161 gcaatggtgc gtgaagcaat caaagcagca gacaatcttg caaaagaaaa tatatctgtt
     2221 gaaatcattg atcttcgtac agttgcgcca ttagatgtag aaacgatcat tcaatccgtg
     2281 gaaaaaactg gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg cgttgccgcg
     2341 caagtagttt ctgagatctc agaacgcgct atcctttcat tagaagcccc aatcggacga
     2401 gtttctgcac ctgatacagt cttcccattt ggacaagcag aaaatgtctg gttgccaaat
     2461 gcaaaagata tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa gaagggacga
     2521 aacaaagtca tggcttatca atttaaattg ccggatatcg gtgaaggaat cgcagaaggt
     2581 gaaatcgtca aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta
     2641 gaagttcaaa atgacaaatc agtagaagaa atcccgtcac ctgttacagg aacggttaaa
     2701 aatgtgattg ttccagaagg taccgtagca aatgttgggg atgtattagt agaaatcgat
     2761 gcaccaggac acgaagacaa tgaaggggac agtggtgtag ccgcagaatc ccaaactcca
     2821 gctaaaccgg ctgctgaacc cactgttgat acagaatcag ctggatcgtc aagcgaagga
     2881 gtcttccaat ttaagttacc ggatatcggt gaaggaatcg cagaaggtga aatcgtcaaa
     2941 tggttcgtca aaccaggaga tacgatcaat gaagatgata cattactaga agttcaaaat
     3001 gacaaatcag tagaagaaat tccgtcacct gtcacaggga cagttaaaaa cgtgattgtt
     3061 ccagaaggca ctgtagcaaa tgttggggat gtattagtag aaatcgatgc tcctggacac
     3121 aatagtgcac cgtcaactag tgcgccatca gctgaagcac caaaagaaaa agtggaaaca
     3181 tcaggttcag caagtgtcgt tgaagctgcc gatccaaata aacgtgtatt ggctatgcca
     3241 tctgttcgtc aatttgcccg tgaaaaagat gtagatatct cacaagtaac tgcaactgga
     3301 aaaggtggca gagtaacaaa agaggacatc gaaaacttct tggcaggtgg tccaagcagt
     3361 gcaccagcga aatcagaagc gccagaagcg gcagcaccga aagaagcagc tcctgcagca
     3421 gaaagcaaac cagctgcacc agcaaaacca ttcaagtcca acttaggaga cttggaagaa
     3481 cgtgtagcaa tgacgccaac acgtaaagct atcgctaaag caatggtcaa cagtaagcat
     3541 acagctccac acgtgacatt gcatgatgaa gtagaagtgt ctaaactatg ggataatcgg
     3601 aaacgattta aagaagttgc tgctgcaaat ggtacgaaac ttactttctt gccatatgtc
     3661 gtgaaagctt taacagcgac tgttaagaaa tacccagtat tgaatgcatc tatcgacgat
     3721 gcaaaccaag aaatcgttta taaacattac tacaatatcg gtattgcaac tgatacggat
     3781 cacggactat atgtaccaaa tgtgaaagat gcagaccgca aaggaatgtt tgctattgca
     3841 gacgaaatca atgagaaagc aaaattagct catgacggca aactatctgc agaagatatg
     3901 cgcaatggaa caattacgat cagcaatatc ggatctgtag gtggcggttg gtttacacca
     3961 gtcatcaact atccagaagt agctatttta ggtgtaggaa cgattgcaca acaaccaatc
     4021 gtaaatgctg aaggcgaaat cgttgtcggt cgtgtgatga aactgtcatt aagtttcgat
     4081 caccgtatcg tagatggagc aactgcgcaa caagcaatga ataatatcaa acgtctttta
     4141 gctgatccag agctattaat gatggaagga tgataaacaa atggtagttg gagattttgc
     4201 tgtagaatta gatacagttg taattggtgc gggacctggt ggctatgtag ctgccatccg
     4261 cgctgctgaa atgggacaaa aagtagcaat cattgaaaga gagtatattg gcggtgtttg
     4321 tttgaatgtc ggctgtattc cttcaaaagc actgatagct gcaggacacc attatcaaga
     4381 gtcactagat tctgaaatgt ttggagtaac tagtgaaaac gtcaaactag attttgcaaa
     4441 aacacaagaa tggaaagaaa acaaagttgt ccatacgttg acttctggtg ttggtttcct
     4501 attaaaaaaa cataaggttg aaacaatcga aggagaagcg ttcttcgtag atgatcacac
     4561 actacgcgtc attcatccag attcagctca aacttattcg ttcaataacg caatcatcgc
     4621 aacaggttcc cgtccaatcg agattccagg atttaaattc ggaggacgtg tgttagattc
     4681 tactggcgga ttagcattga aagaagtacc taagaaattt gtgatcatcg gtggcggtgt
     4741 gattggtgcc gaattgggcg gagcgtacgc aaacttagga gcagaagtaa cgattcttga
     4801 aggctcacca caaattttac caacttacga aaaagatcta gtaaaattag tagaagatga
     4861 tttcaagaaa aaaggcgtaa cagtcgtaac gaatgcaatg gcgaaagaag cagtcgataa
     4921 cggtgacagc gtgacagtga aatatgcagt ggacgggaaa gaagaatccg ttactgctga
     4981 ttatgtgatg gtcactgtag gtcgtcgtcc gaatacagat gatatgggct tagaacaagc
     5041 gggtgtcgaa gtaggagaac gaggattgat cacggtggat aaacaaggac gtacgaacgt
     5101 acctaacatc tatgccatcg gtgatatcgt tccaggggcg gcattagcac acaaagccag
     5161 ttatgaagca aaaatcgctg ctgaagcaat ctctggcaaa aaagtagctg tagattataa
     5221 agcaatgccg gcagtagcct tcactgatcc tgaattggct tctgtaggta tgacgatcaa
     5281 agaagcaaaa gatgctggta tcgaagcaaa agcatataaa ttcccatttt cagggaacgg
     5341 tcgggcatta tcgcttggta aaacagaagg attcatccgt ctagttacga cgatcgaaga
     5401 taacgtgctt attggcgcgc aaatcggtgg agtcggcgca agtgatatgg tctctgaatt
     5461 agctttagca atcgaatcag gaatgaatgc tgaagatatc gccttgacga ttcatcctca
     5521 tccatctctt ggcgaaatcg tcatggatgc ttcggaatta gcattaggtt taccaatcca
     5581 tatttgattt gaataataca ggcgaaacgc aactgaaaaa tcagttgcgt tttgtttttt
     5641 agaattatca ataatattat tatgtaaact taaaaatatg acaacttctt ggtttattac
     5701 cacttcctat gctacactga agaggaatat gaaataggag agttgaagat gcaagaatat
     5761 cagtatccac ttgatttaga ttggacaaca gacgaaatgg tcattgtaat gaagatgtgg
     5821 gaagatctgg aacgtgcgaa tgaaaaaggg ataaacaatg aagctttttt gaagacttat
     5881 cagcagttta aaactgttgt caaatccatt ggtgaggaaa aacgattggg acgggaattt
     5941 gaaaaagctt ccggttattc tttatatcgt acagtgcagc aagcaaaaaa aaatccaaac
     6001 aaaactttga gaatgaacgg gtgagataaa tggaacagat gattgatcat atcaagtcct
     6061 ggcttgaaga agctggtgag aaaatcaaat cttctcaaca aacattaaca atctcgcaaa
     6121 aatcaaatcg aacggatcta gtaacaaatg tcgatcgaaa catccagaat tttctaatcg
     6181 aaaaaatcca ttcctttgat ccagaggcga aaatattggc agaagaagaa gggtgtaatc
     6241 aattatcgga tctcgatgga agagtcttta tcatcgatcc tattgatggc accttgaatt
     6301 ttgtgattga aggggaaaat ttttgtatta tgctcgctgt ttatgaatcc ggcgttggaa
     6361 agcttggttt catttatgac gtgatgagaa atgaactttt ttggggtgga aaaggaatag
     6421 gcgtgtataa aaatgatgag ccattgccta gaccagcaaa taaatcctta tcggaaggct
     6481 tacttggtgt gaatagttat cttttcggtc ataataaata tggaatccga gaaattgcgg
     6541 aaagcagcat ggggacacgt atgtacggat gcgctggtct tgaactagtg gcaatcttga
     6601 aaggaaacca cattgcttat atttcaaacc ttagcccttg ggattatgca gcgggaaatg
     6661 tcttattgga agagtttggt atggtaacaa gcggtctttt tggtactcct ttgacatttg
     6721 aaaaaaggga atactattta gcagggactt cttgtgcata tgcagaaatc gcagaccttt
     6781 tgaaaaaaga aggctgaaaa aaaggtagaa atcattcaca aaaatgataa aaacgagcaa
     6841 aagattaatt ttctcgaaaa aatgaaaaca ttttactata tttcatgaaa aaagtctgct
     6901 ataattagca gtcgagtaaa atttgccctg tcataaagaa ccaataaaaa aggagttagt
     6961 tacattgaat tatagaaacg atatccgtaa cgtcgcaatt attgcccacg ttgaccacgg
     7021 aaaaacaaca ttagttgatg aactattaaa acaatcagat acattagacg cacatacgca
     7081 attgcaagaa cgtgcgatgg actcaaatgc gctagaaaaa gaacgtggta tcacgatttt
     7141 agccaaaaac acagctgtag actataaagg tattcgcgta aacatcatgg atactccagg
     7201 acacgcggac ttcggtggcg aagtagaacg gatcatgaaa atggttgacg gcgttgtgtt
     7261 ggtcgtagat gcgtatgaag gaacaatgcc tcaaacacgt tttgtattga aaaaagcact
     7321 ggaacaacat atcacaccaa tcgttgtcgt aaacaagatt gacaaacctt ctgctcgtcc
     7381 tgagcatgtc gtagatgaag ttcttgaact attcatcgaa ttaggagcag atgatgatca
     7441 gttagacttt cctgtgattt atgcatctgc actaaatggt acgtcaagct tgtcagatga
     7501 tccagcagat caagaaccaa ccatggcacc tatttttgat acaattattg aaaaaatccc
     7561 tgctcctgtc gataacagcg acgaaccatt acaattccaa gtttcattac ttgactacaa
     7621 cgattatgta ggtcgtatcg gaatcggacg tgtatttaga ggaacaatca aagtaggaga
     7681 ccaagtagca ttaattaaat tagacggaac agttaagaaa ttccgtgtaa cgaaattatt
     7741 tggtttcttt ggactaaaac gtctagagat tcaagaagca aaagctggag acttgattgc
     7801 tgtctcaggt atggaagata tctttgtcgg tgaaacagtt actcctgtgg atcatcaaga
     7861 tgcgttacct atccttcaca ttgacgaacc aacattgcaa atgactttct tagttaataa
     7921 ttcaccattt gccggtcgag aaggtaaatt cgtaaccgct cgtaagattg aagaacgttt
     7981 gatggcagaa cttcaaacag atgtatcctt acgagttgaa ccaacaaact ctccagatgc
     8041 atggacagtt tctggtcgtg gagaattgca tttgtctatc ttgattgaaa acatgcgccg
     8101 tgagggatac gaattgcaag tatctcgtcc agaagttatt gaaaaagaaa tcgacggtgt
     8161 aaaatgcgaa ccgtttgaac gcgtgcaaat cgatacacca gaagaatata tgggtagtgt
     8221 tatcgagtcc ttgagcttac gtaaaggtga aatgcaagat atggtccata caggaaacgg
     8281 acaaatccgt ttgacattct taacacctgc ccgcggtttg attggttatt caactgaatt
     8341 cctttcaatg acacgtggtt acggaatcat gaaccatact tttgaccaat atctgccaat
     8401 gcttcctggt caaattggcg gacgtcacca aggggcgctt gtttcgatcg atacaggaaa
     8461 agcaacgact tattctatca tgagtatcga agaacgcggt acagtcttcg tagaaccagg
     8521 tacagaagta tatgaaggaa tgattatcgg ggaaaacagc cgtgataatg atttgactgt
     8581 caacatcacg aaagcaaaac aaatgacaaa cgtacggtct gctactaaag accaaacatc
     8641 tgtcatcaaa aaaccaaaac aattgacgtt ggaagaatct ttggaattct tgaatgatga
     8701 tgaatattgc gaagtaacac cagaaagcat tcgcttgaga aaacaaattt tagagaaaaa
     8761 tgctcgtgaa aaagcatcta aaaagaaaaa ataatctgta aaaggatgaa gagagaaacc
     8821 agcttgttat aaaaaatagc tggtttcttt ttttgtccaa ctcttttctg tggagaagtc
     8881 atctttgtca atggacataa attcagaaaa tacgccgaaa gacgtttaaa agacttttaa
     8941 aaaacttatt tctagagagt ttttgtttca taataagata atgtttcacg aaaggagatc
     9001 aacttgtcct tcgaagaaaa tcgaagtaaa atggcaagag aaaggagcgg gaagatgaac
     9061 gacttattaa aacaatactt tggttatgat gagtttagac ctggtcaaaa agaaattatc
     9121 cagaaagtca ttgatcagga aaatgtatta ggaatcatgc ctaccggaag tgggaaatca
     9181 atctgttacc agcttccagc tttactatta gatgggctta ctgtggttgt gtccccttta
     9241 atctctttga tgaaggatca ggtggacgcg gcgaatcaat taggtatacc cgccactttt
     9301 atcaatagct cgttagatgg ttacgaaaca gctagacgct tccaagaaat cgatagacag
     9361 cagtaccgtt tactttatat cgctcctgaa cgttttatca tgccggattt tatccaagca
     9421 atgaagcgat ggaacgtccg tatgatcgct attgacgagg cacattgtat ctctcagtgg
     9481 gggcatgatt tccgcccaag ttatttacag atggcgaacc agctagatca actgccaaat
     9541 cgtcctgtaa ttgttgcttt gacagctaca gcgactgtgc aagtagctgc tgacataaaa
     9601 agactttta
//
LOCUS       DAFTHM010000097         9527 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFTHM010000097 DAFTHM010000000
VERSION     DAFTHM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.097"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(25..162)
                     /locus_tag="L7C88_002294"
     CDS             complement(25..162)
                     /locus_tag="L7C88_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBP9559097.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
     gene            complement(159..1343)
                     /locus_tag="L7C88_002295"
     CDS             complement(159..1343)
                     /locus_tag="L7C88_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBP9559098.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(1599..1853)
                     /locus_tag="L7C88_002296"
     CDS             complement(1599..1853)
                     /locus_tag="L7C88_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559099.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            complement(1878..3020)
                     /locus_tag="L7C88_002297"
     CDS             complement(1878..3020)
                     /locus_tag="L7C88_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBP9559100.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            complement(3080..4432)
                     /locus_tag="L7C88_002298"
     CDS             complement(3080..4432)
                     /locus_tag="L7C88_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBP9559101.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            complement(4503..4847)
                     /locus_tag="L7C88_002299"
     CDS             complement(4503..4847)
                     /locus_tag="L7C88_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBP9559102.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            complement(4857..5231)
                     /locus_tag="L7C88_002300"
     CDS             complement(4857..5231)
                     /locus_tag="L7C88_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBP9559103.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            complement(5244..5558)
                     /locus_tag="L7C88_002301"
     CDS             complement(5244..5558)
                     /locus_tag="L7C88_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBP9559104.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(5672..8897)
                     /gene="fss3"
                     /locus_tag="L7C88_002302"
                     /pseudo
     CDS             complement(5672..8897)
                     /gene="fss3"
                     /locus_tag="L7C88_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
     gene            complement(8976..9398)
                     /locus_tag="L7C88_002303"
     CDS             complement(8976..9398)
                     /locus_tag="L7C88_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559105.1"
                     /translation="MSEQELLEIVEAFIKCEKITSQRMYEQKSVGKNIPSLSTIKKML
                     GDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQDDLSMTKFRKLVQSPKLPSVDTI
                     MKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKKTK"
BASE COUNT         2544 a         2185 c         1629 g         3169 t
ORIGIN      
        1 aaattttgac cgaaattcat ttcatcactt tcctttcttt tccattgctc ggtccgccgc
       61 tgcacttgca tgcatcaagc acatcacagt aacaccaagc atactgccac caaacaccaa
      121 taaaatatct ttcacaattt ccatcacgat tcctcttttc atataatcaa attttcaatt
      181 gccatacttt gttgctccaa aatctttttg tgccggtctg atagtcgagt attatttacc
      241 atatcctgaa tgtacgttgt ctgattcaac cgatccaact ccttggccat cttccacgta
      301 ggggcgactt gtcgtccaag ccagttcaac gttcgttcaa tggtataagg cttcggttca
      361 gaagttaatt gaatttcctt ctgattccgt ccaatgaagc gcccccattg ttcattcaag
      421 ggccagttag ttcgcctttt gccttccacc ttatccgcaa atcgcaagta ccggttaata
      481 atggaaaatg tggtactttc aatactgcga ccttttaaca aatcttgaat tgcatgataa
      541 gctcgatcat ttttcagtcg gatttcaaaa cgatttttcg tttcggtctg gtctaaagga
      601 atccctaact tgatatattg ctcatagtct ttttcgtaca aacagaaata gacctcactc
      661 ttaagactgc caatatacaa agtattgccc ataccatctt tatcatcagg tttcaacagt
      721 tccccggaac gatagctttt gaaggtacga aacaaggaga tacattcttc cttctgacat
      781 tttttcgtta aatcaggaat atctaacagg ccaactcgat cattgattgc caggtctaag
      841 cgtttcatca cgccaccggc ttttagacaa tcttcgaaaa agtcatacca gctacgcttt
      901 tgggcgagta aaaaagtttc aaactgccga caaccacgac cctttaattc taaaaggacg
      961 cctttatctt cttcatgtga caacatcacc acaatatctc ccataacata ttgttcttga
     1021 taggagtaaa aggcgtaatc ttcgtggagc atataatcaa atttcaaatg gagaatctct
     1081 tgaatgattt tcctcgcatc cgttgtggga aagcgaatcc ttacatagtc aaacagtaac
     1141 gttaaaggta actcgggatt gaaactttcc agttggtcaa aaattttcct catggttttt
     1201 gtcgatgcgg ttacgccacc attttctatc tgatttaagt acgggcgact aagtccacaa
     1261 gtcgtagcta atttattttg tgaaacgcca tattcattac gccggtcttt taatagccga
     1321 taatctaaat tcctttgtgc caagttctca cctccaaatt taaggtgtta actttttcaa
     1381 atcagttaac atctacacaa attgcttatt atccttgata ggacagccat tccttatcgt
     1441 tgcttgctta ttttttgtgt ttttgtaccc ccctgttaga tacggggggt gagacatcat
     1501 ggccggctaa cgccgtccat aaacaggcac agcaccacgg aggatttctg cttcgcaaat
     1561 cccccgcggt cagtgcctat cagtggttta tttggccgtt actccgcggt aataccctca
     1621 atttccaact ctgcttttat ctcaaacaag tattggcgga tatcaggttc tttagcaaag
     1681 tccgcaattc gttccaattc actgatgact tgattcagct ccattcgagc atccgtttcc
     1741 tcatcaatta catacggatc atcagggact ttcaccccgt ttttgcgaat atcaaaattg
     1801 agccggtaca gttcttcttc caattccgga tctgactgaa tcttgccaat cacccagtag
     1861 attccccaat caactcatca taaatcatct gtttttacct cctttaatct tctagcaata
     1921 tcaaaaatga ccggaactgt tacagaattt ccagcctgct tatacaactg actatctgaa
     1981 ttgacttgag aagctcgatc aaaagcccag tccggaaagc cctgaagccg ccagcactcc
     2041 ctaggtgtta actttcgaat ttgatactga tccgtgacga ctgcttgttg gtctcctgtt
     2101 aataaggtat gcacactttg ttttcccaga cggcctcgac gacttgtgga attaggaaaa
     2161 gccaggttca cactgttccc tggcttcacc tcttgatatt ctgtttcgtt tttccgaagc
     2221 atgatcttcg ttccgccttg tttcgttgac aaagtaggcg ctgttccagt tatctcataa
     2281 acccgattgc cttgttcaaa atttcccagt aacatacccg ctacagaaat tccatcatct
     2341 accggcaatg cgattttgat tccttcatca ccggtcaagg taggcgctac gtcatctgac
     2401 ccatagactt gtccccccat tcctcgattg gaagggttga tatttaataa gtttctgatg
     2461 ttttgatcag atgttggaga cgatccaatg ataggaaata cttgttcggt acatgcgtct
     2521 cgagaatgtc cgataaggaa gatccgctca cggttttggg gaacgtaggc ctttgagtta
     2581 agcacttgcc attccacatc ataccccaat ccatccagcg ttcggaggat cgtctcgaac
     2641 gtagcccctc cttcgtgatt gagtaatccc cggacgttct caaggaataa aaacttaggt
     2701 tggagaatag cggcgaaccg agcgatttca aagaataaag tacctcgagt atcggaaaat
     2761 ccttgccgct ttcccgcaat tgaaaaagct tggcacggaa atccaccgca aaggatatcc
     2821 actggtccga gagattgaat aaactcgtct gatacacttg tgatgtcatg catttccacc
     2881 tccttacttg tatcatggat tgccttataa ctctggcgag caaaatcatc aatttcacaa
     2941 aagccgatac actggtgacc cgcttgttcc atacctaagc aaaagccacc aatcccagcg
     3001 aataaatcta aaaatgtcat aaatcacctc gtaaaaaaag cccaggattc ttgacactcc
     3061 taggctacat actattattt tatccttccg tattaacgtt taatccacca atgtcgctaa
     3121 tttcccttaa gaaatcatat ccttttggta caagtggcgt ataaaactca ctaatcacac
     3181 tccctcccgt atctacatag cctcgacctt tgatacgctt cataaagaat tttttatcaa
     3241 cctcgccaaa catcatggaa tatcccagtt cactcatacg acccaaagcc acccggaaat
     3301 taaattgatc gcgaatcccg tctcctaaat atttcgcatc cggtctttga caagctagaa
     3361 tcagaaagaa accagattga cgacctaaca tcacgatttg tttgagctta ttcaaaatca
     3421 ccgcactttc cttcgtcgtt aacatttcca tataaaccac gtattcatca aagattaaaa
     3481 agtttggtgg aagtccaaga aacgcataat tctctcctgt tttgtagttg ggcatttctt
     3541 tcattgcctt gctacgagtc atcatgcgct catagaaatc ttccacacaa gcagaaattt
     3601 cctccttttg ggaatagaca tgaggcatta ccgtacctaa atcggctaag tccgcatttt
     3661 tgggatcaag aacaaaaagc tcggcatcag attttaataa agcctcgatg atagtgagta
     3721 aaaagtaagt cttcccacca cctgtgccgc cagcgattaa catatgaggt aaagaatcat
     3781 aagcccatac ttgatttttc atcaatcgca aagccccact ttctgccact acttcgtcta
     3841 tcccaattcg attggcaatt atatcataca gtaaagtgta ctccacatag gagtctttga
     3901 gttccttttc tactagttca caatatagac cactttctaa cttcttttcc agctttaaaa
     3961 gctgatcttg atattttccc agtgaaattt gaacgcgaat agaaagtaaa ccatccttca
     4021 tacggtaata gattttgggg aagtaactga ttgtctcttt ggttcgacta ctattgaggt
     4081 ctttgaaaaa tccttcactc tgagtttgtt ttacttcgta ccaatgattt tctagaatca
     4141 tccgggctag cttttgtcga tgccacaaac tgcgccaatg atcctgaaaa aagtgtatat
     4201 aaagcaacat cgtgcttcct gaaagaacga gacttcctag caaatagatt aaatctttta
     4261 tagaacgaac gatttctata gtagaaagtg atagcttaga aatatcaaat tgtctaagct
     4321 cttgaaaata aaagacgctc atccaaccga tgaacagagc gagtagccag ccaagaacaa
     4381 agtgataaac caagtgctga tctcctgccc gtatacgatg ccctttgtac atttttatgg
     4441 tttccacctc caatcgaaaa aagcttcata ggatttcatt gatccaattt caagcagtta
     4501 tgctagtcat ttactgctat agggagttgt ttcgtttcca ctagttgctt taaaaaaact
     4561 tcaatggcat ccggcatttc cacaccaatt tcttccaata cggtttcggc ttctcgacat
     4621 agactttcat ttacttcgat aaccataaag aaggactctt cttcccctaa ccaattcagt
     4681 acatcaaaat cttcttcggc atcgttacct acttccagta acccttgatg cataatcaga
     4741 aacatttttt catcataggt taatgcttta gtgagttgtt cctccgttag ctcacctttt
     4801 ccatattgat cgagacaatc taaaatatgt tcaacattaa tttccatacg cttcacctat
     4861 ttctttcctt cattttggtt tgtagaattt ccctgatctg gttgtcgttt caagactaaa
     4921 tcatcggcct taatgaacca attgacagta gttccttctc ggaaaacata attggcgacc
     4981 gtatccatga ttggattgac caactctacc tctgcgtcat aggcaaactc gcgtaagggt
     5041 acatttgctg ggatactaac ttggatcatt cgaccttgcg cagaggattt caaattataa
     5101 gtccgttctt ttacctcgtt actaaccgtt ccatcctcat tttgcttccg tacttctcgg
     5161 cgtaatgcgg aaaatcgtaa tttcccaaac gttagtcctg aatctacaac aataccttct
     5221 gttaatctca tcttcttttc ctcctatgct ttcactaaat catcgacata caacacgtag
     5281 tcggtaaacc cacgattctc aatctcatag cctttggcaa ccaaatgggg attcacggct
     5341 tttagtggtt gatcttgatc aaaatccttt tcgccggctt ccgcagctac caccacttca
     5401 atatcatcgg ctcgttgctt actggaatac aaatgataac tacgaccaat tactgtagta
     5461 ttccgcccat atccttcagt taaaacttcg ccttcgccgg cataccttat ctttccaaag
     5521 gtttcggcca tatctggcac aacaaatttc aattccatct tcttttcctc ttttcatttt
     5581 tagttttgga tacaaaaata gcgcgaccac tttttttagg aggcggtcgc gcacgttggt
     5641 ttttcctatt tagttgtttc atcacatcac cttagtttcg gcgattccag aaataatacc
     5701 cagcagtcgc aaagatcaag gtaaacccaa taaacagcag aacattagaa tttttctccc
     5761 ctgtttgtgg gaatgtcttt actgtaggac tagattcttg agagtcactt ggaacagttg
     5821 gtatttccgg ttgttctggt gcacttggtg ttgtcggaac ttttttaggt gttaaagttt
     5881 gagttttttc ttttagatcc tcattgtgtt tcccattgat gtttccgtct ttgccatagt
     5941 taatttcttt gaaggtaaaa cttgtacctt ctggatattt acttgtgtcc actttttccg
     6001 caagtacggt tttagtgaat tctttgtcat tcacttcata atcaattttg ccagatttcc
     6061 aaatttcttt ggtcgtatta tccggaagta atgcatacag aattgtttca aaagcttctt
     6121 ttgagccatc cagtacatca tgggtaatcg acacatcatc gaacatatcc accacatccc
     6181 catgagtaaa ggtttgcgaa ccatcttcta ggtgggcttt tgtttggatg gaaacatggc
     6241 gttccaccgt acaattgaca gtttgggctt gattgttcaa gctagcatct ttcgctactg
     6301 gatcatcacc tgcttcatag ggtttcttgt tttcatacac atagttgaat aagacgatgg
     6361 ttttatccaa aacttgttct gcggttaatt tatgcaaaat tttccaagtt cctgttttct
     6421 ctttattcgc caacgttgcg gttgtttcgg caattaccac tggtttggct ttttcatctt
     6481 tttcttgggc agcttttgtc gcttccacat caatggcttg cgctaccaca taccagtctt
     6541 ctttgatttc atgcaagtta tagctcaatt tatcaactag ctcggtagaa tcaaggtctg
     6601 tcaattcttt gcctccgtct ttccaagtcc caagagaagt taagctatct tcttcttcag
     6661 gtaaatcata gagcatcaaa cgattcaagc taacagaaaa tgctttattc gtcagtttct
     6721 cgtaaggaac ggtcaccgtt ttaattggtt gtttttgtcc tttttcggta atcgtaaaaa
     6781 tgtattcact cttagtgtaa tccgctttat tttctttaaa agtagaacgg atttctaatg
     6841 gcgtaatttt ttgaaatcct tctggagcct ctacttcttc aagtaaataa tccccataag
     6901 gaagattttc aaacttgcca tagccatcaa aacctagttg ctcgttataa gctgtaattg
     6961 cttcatcttc ggcacctgta atctcactgg ttccttccaa tggcgatact ttaaaggtca
     7021 gatcattgaa gccagtttcg gcagtcccag cagctgatcc agcaaattta aagaaatcaa
     7081 agccaaagcg aatgacttgt tcttttgccg taacatctcg ggtaatcacg gcattttttt
     7141 cgttatcatc cacctttttg atggaaacag ggtactttgt ttcatccaag gtatatcctt
     7201 caggtgcttt ggtttcttgc cagtaatact cattaatcgc taagtgttta acagcaactt
     7261 gattcttttc atctaaagtc aaagtcaccg tttcatcaga agctttcgtt cccttcacta
     7321 actctggttt aaaagcctca ctccatttga ccgcttgacc atcttttgca gtaaagagag
     7381 tatattcagc tcctttaaac tcagctttac cttgagtttc attaccggta tctttgtctt
     7441 cttttgtcaa agtggtttca ccagtgattt cttggttttg cccttttacg ttactggtaa
     7501 caagagccac ggtttgattg acatagttca attcgacttt tactggttta aaggtattca
     7561 caaagccatt actagctttg gtttcggtca cataataggt tcccaattcc aacgcattgg
     7621 caatctcttt tggtgtttcc gcatgacctt tttcatccgt ggtcatttct tggacaattt
     7681 caccggttgg actgtctttg cgaatggcaa acgtatttcc ggctaatgag tatttgtcgt
     7741 tccaaagatc agttcctgtt tccaccccca ttttattcaa aatgatttga cctttttcgc
     7801 gagtattttt tgaagtcaca gaaatagtct caccagattt aatggttgcg gtgattggtg
     7861 tagtgtcaat cgtataagga gctggcactg atttttcagt aatggttact ttcgcgccat
     7921 gaggaatctc atccaatgtc gcaatgcctt ctttatcggt ggtcacgtct tttgcaggta
     7981 atgtttttcc aaagtctaaa tggaaaacgg ttcccggtac aacatttcct gtttctttat
     8041 cgactttttt aatcttcaaa gaaccctcag tttccacatc aattttgatt gtgtaggtat
     8101 tgggcttatc aattgccccc gccatcaaag tttgttgacc agccatttta taagctaccg
     8161 gtgttcctgt attagctgac ttctttaggg ttaattcacc actctctttt gaattggcat
     8221 ttggagtaat cactagttga ttgccgttca cacgataatc aatatttgcg atattctcga
     8281 caacttcatc aaactccgat aaattcaagc cgttcgtatc tgtcacagta gtcgattgac
     8341 ctaacacggt tttcactgtg gagttatgga agcttggttt cttttgataa tccgcaatgg
     8401 cttgattgat ttttgactca atggctgcga tatttactgc actaccatca gaacgtttaa
     8461 ttgagtgaag cgtagccatt aacttcttgc caaatcatct tctgggccac aatatgtgta
     8521 tccacatccg taccagcttc cttccataaa acggaaacta atttcgcttt ctccgacata
     8581 tcaggcaatg gatttttctc ataaccagga gtgaactcat tgtaaatcgg cacccctggc
     8641 tcaatacaga aaatatcttg cttcacacca ttgtaaactg catagtgcgg aacggtaact
     8701 tctgacatgg gacgaccatc gctaaatgta ccttcgacag catactggtg agccaaatcc
     8761 aattccacag ttaccgtttg tggatgagta atttcatcag caaaggcaat cgttgggcca
     8821 agcgatccac caattgtttg gcataataga ctcagtgttg cgagcaaacg ccaattctta
     8881 aatcttggct ttttcataaa ataaatctcc tttcgttttt gggtaataaa aaagacgtcc
     8941 aaattttaat tttgaacgtc tgatttagag tgatactatt tagttttctt tgtcttggat
     9001 aggttgtttc tctgcttata aattttgatt cttcgataat caaatccaat ctctgccatc
     9061 aattcctccc aatttttgtt cgttcttttc ataattgtat caactgatgg tagttttggg
     9121 gattgaacta gttttcgaaa ctttgtcatt gataaatcat cctgtagttt taatcggatt
     9181 atttcatttt ttagttctaa cagcagttcg aaatcagtaa atcgagatcc atcatttttt
     9241 tctttaaaaa gtggacgtat atctcctaac atctttttaa tggtactaag tgaaggaata
     9301 ttcttcccta ctgatttttg ttcgtacatt cgttgagagg ttatcttctc gcacttaata
     9361 aaggcttcta ctatttccaa taattcttgt tctgacattc tagcccattt tccataccca
     9421 gtattttctc gtcctatact aatcaataaa ttctcccatg atccatattt tttgttaatg
     9481 aaccacatac ttggtgcaga atttggattt tctgatagct ttttctg
//
LOCUS       DAFTHM010000098         9434 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFTHM010000098 DAFTHM010000000
VERSION     DAFTHM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.098"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..152
                     /locus_tag="L7C88_002304"
     CDS             <1..152
                     /locus_tag="L7C88_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9559106.1"
                     /translation="NFAKNQGYNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIY
                     MKKTL"
     gene            complement(230..763)
                     /locus_tag="L7C88_002305"
     CDS             complement(230..763)
                     /locus_tag="L7C88_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBP9559107.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(857..2035)
                     /gene="mutY"
                     /locus_tag="L7C88_002306"
     CDS             complement(857..2035)
                     /gene="mutY"
                     /locus_tag="L7C88_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBP9559108.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(2028..2825)
                     /gene="recX"
                     /locus_tag="L7C88_002307"
     CDS             complement(2028..2825)
                     /gene="recX"
                     /locus_tag="L7C88_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBP9559109.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            2932..4314
                     /gene="rlmD"
                     /locus_tag="L7C88_002308"
     CDS             2932..4314
                     /gene="rlmD"
                     /locus_tag="L7C88_002308"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBP9559110.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(4488..5066)
                     /locus_tag="L7C88_002309"
     CDS             complement(4488..5066)
                     /locus_tag="L7C88_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBP9559111.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            5388..5858
                     /locus_tag="L7C88_002310"
     CDS             5388..5858
                     /locus_tag="L7C88_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBP9559112.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLTMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(5966..7192)
                     /locus_tag="L7C88_002311"
     CDS             complement(5966..7192)
                     /locus_tag="L7C88_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBP9559113.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(7946..8146)
                     /locus_tag="L7C88_002312"
     CDS             complement(7946..8146)
                     /locus_tag="L7C88_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBP9559114.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(8280..8888)
                     /locus_tag="L7C88_002313"
     CDS             complement(8280..8888)
                     /locus_tag="L7C88_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBP9559115.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(8973..>9434)
                     /locus_tag="L7C88_002314"
     CDS             complement(8973..>9434)
                     /locus_tag="L7C88_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBP9559116.1"
                     /translation="YRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYFDLS
                     MALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMGAMV
                     LLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
BASE COUNT         2799 a         1891 c         1561 g         3183 t
ORIGIN      
        1 aaaactttgc taagaatcaa ggctataata cgattttatt aggggcacag tccacagctg
       61 aaacttttta cgaaaaacta ggatatacag cttacggcga tccttttgaa gatgctggca
      121 tgcctcatat ttatatgaaa aagactttat aaaaatttat ttcgaaaaaa gcaaaaaaca
      181 gcaagctttt gagaaaaatc tctcactggc ttactgttct tttttgtgtt tacttacgcg
      241 acaattgctt gtaacggtta taccaaatat caatatagcc ttccgagaac gggccatctc
      301 cattattgat ccagtcaacc agaatcttca cattttcttt taggatgaag tcaatatcgt
      361 tcgggtaatt catcattttg ctgtgcatct catattcatc gacatccaat agtcgtttct
      421 cgccgtcagg aaataccttg atatccaagt catagtcgat atatttcaag gcctcatcgt
      481 ccagcaaaaa aggtgaagct agattacaat aataggaaac ccccttttct ctgatcattg
      541 ctattacatt gaaccagtat tttttatgaa aataaacaat cgctggttcg cgcgttaccc
      601 atcggcgtcc atcagattca gtgactaatg tgtgatcatt cacgccgatc atagagtgtt
      661 cgcttgtttt taataccatg gtatctcgcc acgttcgatg caatttgccg tcgtgcttgt
      721 aactttggat cgtcacaaac tctccttctt ttggaactcc catagcaacc cttccttaag
      781 cagcattttg tgctttgtgt ttgggtgttc attacaccga catcataatt attatatcaa
      841 taaaaatgag ctttgcctag aaaggattcc tattgtttcg atttttctct aactgatcta
      901 ccagtttcat ttggacctta ggaaaaacga ccgaatcaaa tgcatcaggc ttcaaccact
      961 tcgaagtttt gttctcggta aattcttgtt ctgctccctc ggttgcccgt ccgtaaaaaa
     1021 ggagaacatg ccatttcaga tgactaaaaa tatgagtaac ttctcctaaa tgtcgtgtct
     1081 gccaaacaaa gagttcctgc ttttcaaatg ggagattttg ctcttcttct gctactaggt
     1141 catcaaacag atcgatttct ggctttgttt cccattcttt tttcaatcgc tcatactcct
     1201 cttgtgtcac ttccatcatt ggaaatgtcc acatattcgc cagcaatttt tggctatctc
     1261 tttcttcaaa ataatacgct ccagaatgat tttgaagagc tgcactgata taataaacgt
     1321 cttttggctt tgcttttttt gtttttacag gaaaactcgt ttggattcct cgtttgttag
     1381 ctaaacaaaa ggcttggatc ggacaagtct cacactttgg agaagttggt gtacagatag
     1441 ctgaacctag atccatcatt gcttggttga attcacctgg atgcttttca tcaatgattt
     1501 tccgcatcgc ttcatcaaag attttcctgc tagaagcttt tgcgatgtct gcttcaatgc
     1561 aaaacaatct gctgactact cgcatcacgt tgccgtcaac tgcaggttct ggaagtccaa
     1621 atgcgatact tgcaatcgcg cctgtcgtat atggtcctat tcccttcaat gagctaattt
     1681 cttcaggcgt ttgcggcatt tccccatcaa attctgacat gatctgttta gcagcagctt
     1741 ggatgttccg ggctcttgag taataaccaa ggccctccca tgcttttaaa agcttttctt
     1801 ctggagcatt tgctagctct tcaattgtag gaaaccattc catgaaacga taaaaataat
     1861 cgatcactgt gtctactctg gtttgctgaa gcatgatctc agagatccag atacgataag
     1921 gatcacgatt atagcgccaa ggcaggtttc ttttttcttg ttcataccat tgaatgaact
     1981 gatcttgaaa ttcttttgtt tctttatctg tccatttttc ccattcttta ttcactttcc
     2041 tcttcctttt ccgtaatgaa tcgctggatc atatccaaat caaatccttt ttgatataag
     2101 ctttgcttta cttttagatt tcttttttta ggttcaaacc ttaaatttct tcgccatagt
     2161 ttatctcctt gtttgactaa ataatcatat tctatttctt gatctgcttc ttgcggaaga
     2221 tcagctatcg cttgttggat cacttcttga gaaaagcctt tcgtcatcaa tgtttgttgg
     2281 atttttctca ataattcttt ttggcttttt ccgtgatttt ttccaaacgc tttttcggct
     2341 gtctgatgtg cattttgaac ttggtcttca aatgtatatt ggctgagcgc ttgttcaatg
     2401 atttcaggtt tcaaaccttt ttgctgcatc tgctgcgcta atttctttgg tcctttgtca
     2461 cttaagcgca tattcgtgcg cacataactt tccccataga ccaaatcatc gacaaggtcc
     2521 aattctttta agcgggctac gattttattt cgatcttctt gaaggatttc cttttctttt
     2581 aagtatgttc ggatttcttt ttccgatcgc aactgataac ttaagtaatt cattgctagg
     2641 tgaaaaccga aatcagctcc gctactcttc ttgatctctt ggatagtttc ttcgtctaat
     2701 tcccgtcctt ttaataatcg atagcgtact aatacatctt cagatacttg taaagcttct
     2761 ccttcagata aatctacgcg atagaaaggg cctttgcctt tactgattct cgtaacggtt
     2821 aacataaaca tcctcctcga acatatattc tctatcatac cacagaaaat ccccgtaatc
     2881 aggtattata tgttagaata aaccacagaa aaaagaaaaa gggagatact tatggcagaa
     2941 acaattgtca aaactggaca aacggttcct ttgaaaatca agcgtttagg cataaatggt
     3001 gaaggaatcg gttatttcaa acggttgatc atatttgttc catatgcact accaaaagaa
     3061 gaagtactag tgaaaatcac gaaagcaact cctcgctatg cagaaggaga attaataaaa
     3121 gtcaaaaaaa caagcaaaga tcgcgtagtg gcaccatgtc ctgtttacta tgaatgcggt
     3181 ggctgtcaat tacaacactt agcttatcaa gctcaattgg attttaaaaa ggatctgctt
     3241 ttgcaagcat tggaaaaatt caaaccagca ggctttcgat cttatcaact tttgccgacg
     3301 atcgggatgg atgagccttg gcattataga aacaaagcac aatttcagtt acgaaaaaat
     3361 aagcagactc aaaaaattga agctggttta tacgaagcaa actctcatca gttagtccct
     3421 ataacagact gcttggttca agaacctcga acacaaaaag taatgaatac tgttgttcaa
     3481 ctattgaata aatttgatgc acccatctat gatgaacgga caaacagtgg aatcttccgc
     3541 acaatcatgg ttagaatcgg tgttaaaact ggggagttac aagttgtttt tattactcgc
     3601 agtaaaaaat tcccgcaaaa aaacgcaatg atccgtgaga tcaatgaacg actgcccgaa
     3661 gttgtttcaa tcatgcaaaa tgtccaggca caaaaaacgt ctctcgtgat gggggatgaa
     3721 acgatccact tatggggaaa agaagccatt gaagaacaaa tcaatgaagt gactttcgat
     3781 ctttctcctc gtgccttctt tcaactcaat cctcagcaga ccgaattgct ttatggcgaa
     3841 ggaatcaaag cattagatgt ccagcctaat gaaacgatcg tggatgctta ttgcggagtt
     3901 gggacgatcg gcttaagtgt agcaaaacaa gccaaagaag tacggggaat ggataccgtt
     3961 cctcaagcaa tcgctgatgc aaaaaaaaat gcggaaagat taggatatca caacactcga
     4021 tatgaagtcg ggacagcaga gcaagttctg cctaaatggt tgaatgaagg ttttcagcct
     4081 gatggtatca tcgtagatcc accacgtacg ggtttggata acgcattgat ccaatcatta
     4141 ttgaaatacc ctccaaaaaa acttgtttat atctcctgta atgtttctac acttgccaga
     4201 gatctggtta atttaagtaa aaagttcaag attgaatatt tacagtccgt cgacatgttt
     4261 cctcagactg cacgttgtga agttgtcgtg aagatgacga gactcgctga ctaaatgaaa
     4321 gaggttgtga aaaagtctgc cctgtatcaa gtaataagaa cagccaaaca aaaatagctc
     4381 ttcatgtttt atgaatactg tacttgtgac cgaagagtta acaggaggac actatttatt
     4441 taaaaaaagg gttgtgacat agtttttgtc acagcccttt ttgattatta ttggatattc
     4501 acgtctatca cttgataaaa tgcatttgtc gtatcgctga tattccatac tgctaaaatc
     4561 acattatatc cttttcgatc ctgcggaagt gtgatcgttt ggttgactgt ttttggtgga
     4621 acagttgctt tgtcgtctat ttttgtgatc aattcaaaat cactaaattt caaaggttga
     4681 ttaggattcc aagttggttt ggtaatgtag taatcccaag tacttgtccg atgttgtgct
     4741 gttaaattcc aagtaatatt taatgttcct ggattaacca tgtttttatg ccatctgtta
     4801 gatgtctgtt catctaaagg ctcaaagccg ctgactcctg cactagcaat ttttccatca
     4861 atgaatgtat ttttggtagc ttcgatactt tgcggttccc attgtgctct tccgacattt
     4921 tgatttaagt ttcctgctgc tgatgttcct aggtatgcac ggcttcctgg agaagtaata
     4981 taaccatgcg caaaacctgg aatgctaaaa ccgaacaacc ctaaactaac taacccaata
     5041 aacaataacg tactaatctt tttcatgtag aaacctcctt catttgataa ccacattgta
     5101 aacgctttat tgtattaaca caaacattat gcttttataa ttttatgttg aagtaaaaaa
     5161 ggtgaaaaaa gtaagatgca gattataaca gaagtagacg agaaaagtac aaatagaaaa
     5221 catgagaatc aaatcatatg atctttttca aaaacatcat tcatataaac aaatgttcaa
     5281 ctttttaata acaacaatta tcaatttttt tcttacttca caaactaaat acaggtcttg
     5341 ctgtgagcct tcatggtaaa ctaatattat agaaaggagt tagtaaaatg aagatgataa
     5401 aagatattcg tttttgggtt tgtgttatag gaattgtcat attaggcttt ttatcagggt
     5461 tgcttagcgg aaatcccgga aaatattact attctttgca acttccacca tttgcaccac
     5521 ctagctggat atttgggccg atgtggacct tactgtatat attgatgggt atttctcttt
     5581 atttgttact taatcacaac aacaaaaaac agcgaaacaa tcttgtcggt ctttttgtga
     5641 ttcagttcat ttttaatttt atatggtctg ctctattttt taatttaaga aatattttca
     5701 ttgcagcaat cgatattaca cttttagtta ttttcttgtc agtgcttatg tatcagttgt
     5761 ggctgcatca tcgcctgaca atgtggctca tgattcctta ttatttatgg gtactattcg
     5821 caactctatt gaattattca atttattttt taaactaagc gctaaaaaga gacgtcctgt
     5881 aatttaacac atagaaaaag tgccacctaa gttagatttt ttgtctaatt taggtggcac
     5941 tctttattaa ccaaactatt tttttctagt acccacttgt tgttccatac tcattattct
     6001 ggtcataacc ataaccattt tgttcctgtc cagcgtaagg atcataactt tgagtatctt
     6061 gacttggtgt atagtactga cttgtatctt ctgtttgctg ataataggta ttcggatctt
     6121 ggtactgatc atatgtgttt tctgaatagg aagaataatc ggtgtaccct tcactattcg
     6181 atccatcacc gtttgtcgaa tcgccatctt ccgaatcatc aaagaacatc attgaagcat
     6241 tctcattttt caaattaggt aatgtatcgc ttgtttttat atttaattgt ttcttcagtt
     6301 cattttggat cgaaagaaga tcattttttc ctaaaatttg atagtagata tcattgatca
     6361 tttgtccttc gccttgcaac tggtcttgtt tgattgtttc aaacgccggg gtgtagttcg
     6421 tcgctacatc aagcatgtca tcccaatcta agtccgtcgt cacattgttc tcaactgctt
     6481 ttaaaatttt tctataattg cttacgccat ctaaacttaa aactttattg acgattttcg
     6541 tcactacttc ccgctgacga cgttgtcgac cgatatcgcc ttctggatct tcgtgtcgca
     6601 ttcgagaata ggctaaacct ttttctccat tcaatgtttg ttcacctact ggtacatgga
     6661 caccatccaa agtaaagtca attttattat tcactttgat gccaccgacc gcattgatca
     6721 aatcttccat gccatccaaa ttgatcgtta cataatgatc aataggaata tcgagcagtt
     6781 gctcaattga atccatggcc atttcgacac caccaaatgc gtaggcatga tttaatttat
     6841 ctaccgttcc ataacctacg atattcgtat aaatatctcg gtccaaactg atgatcgttg
     6901 attttttttg tttcggatta actgttacta ccatcatcgt atcagaacgt ccttgttccg
     6961 ttcttcctaa tccaccggta tctaaaccta atagcaaaac cgaaaaaggt tctttgtcat
     7021 caatgcttac tctctcagaa cgtttggagg atattcgatt agagttttta gaaattttgt
     7081 ttactgtttg gctcgcttct cccataaatc tgattccgta tgctgataat ccggcaatca
     7141 gcaaaacgaa tacccctaac aaggttaata gaactttttg ccatcgcttc ataatacacc
     7201 tctgtttcac attttctaaa atattgtctc atataactgt tcaatcagca aattcacttt
     7261 ttaatcataa gaaaacttta aaaaacattt ttgtgtaacg attattattt tttaaaattt
     7321 ctcaaaattc ttaactatca taccataccg tgaaaaagat cgaaagaccg aatacacgca
     7381 gttcgcaatc gttttatctt tttttatgta ttttttccag aaaaagcgaa caacaaggta
     7441 ttttccaaat aatcgtgcag taaaatgatc gcacatacct ttcccatctt tttaacagtc
     7501 tttgcctacc gttcagatta tcattcgatt tcacgacaat ttcttcctat gactggtcct
     7561 tttgttaaac ccatcttcta ttcgttttat ttccagctca ctgcatggct cttaaaatga
     7621 ctcgaactag tgattgcatt accatcatct tttaatggat agatatgctc ctcttcaaag
     7681 taaaacgatt ttcttttaaa gtaatagaat tgacatggta atgagtatgt atactagtgg
     7741 tttcacaaat ggtcttttat tcaacatcca aaaactgaaa tttctttaaa atccattact
     7801 aacgaagaaa atgttccttg cttgataatt agttaggaca tgtcaagtga acaaatgcat
     7861 ttacttagcc aaaaaatcta aaaacttcat aaatagacaa aaagacacga ctctctaaga
     7921 agtcgtgtct ttattcaaca aattattata atttagtcac ttcagcagct tgaggtccgc
     7981 gtgcaccttc aacaatcgtg aattctactt cttgaccttc ttctaggctc ttgaagccgt
     8041 ctccttgaat tgctgagaaa tgaacaaata cgtcatctcc gccgtctact gtaataaacc
     8101 caaatccttt ttcattgttg aaccatttaa ccgttccgtg ttccataaat gtatatcctc
     8161 caaaaaagtt cttgcaagta accttgcaag aacattatac ccaatttaga aaacgctagc
     8221 aagctttcgc tcttttattt tccaaattat ttttaagact gatatgacgg aggaaatggt
     8281 tattttgctg cttcgaaacg tttgtttact tcatcccaat taataacatt ccagaatgct
     8341 gcaatataat ctggtcggac atttttatat ttcaaataat aagcatgttc ccaaacgtcc
     8401 aaacctagaa ttggtgtctt tccttccatc aatggagaat cttgatttgc agtagaggta
     8461 atagctaatt ttccattttc cattacaagc caagcccatc cagaaccaaa tcgtccagcg
     8521 gctgcttttt tgaattcttc tttaaaagaa gaaaaatcac caaaagcttc attaatcgct
     8581 tcttttattt ctcctgtagg ttcgccacca gcatttggtg ccatgatttc ccagaaaaat
     8641 gaatggttag catgtccgcc accattgtta cgtacagctg tcttgatatc tgttggaata
     8701 gcgtccatat cagataataa ttcttctatt gttttttcgc ctaattctgg gtatttctca
     8761 attgctgaat ttaaattcgt cacataagta ttgtgatgct tatcatgatg cagatgcatc
     8821 gtttcttcgt caatataagg ttccaatgcg tcatatgcat aaggtagatc tggtaatgtg
     8881 taagtcataa aaaaattcct cctcaatgtt ttcttaataa tgtctacatt acaaagagta
     8941 acaaagagaa ggaaattctt caattgttat gcctagtcgt ctttttcact ttgacctact
     9001 tcttcttcaa aaacctcagt ttctttaaaa ataaacaact tgctgaaaat atagttcgca
     9061 aggataacaa taatttgagt gatgattttc gccacatact cattgctgtt cataacattg
     9121 atcaacaata ccattgcccc catgtccaat ccgtaagaaa ggatacggta gaagaagaac
     9181 ttaccgcatt caataagtgc atgtgtaaaa ttcggtgatt ttgaatggaa tacccaaagt
     9241 ttgttcgtta caaaagcaaa caatacagaa caaaaccacg aaatagaatt ggataaggcc
     9301 atacttaaat caaaatattg gcgtgcgaga gcaaaactaa caaaatttac aatcgtagcc
     9361 aaaccaccaa aaaagagata gactagtatc tcccaatatc cttttgcttc taaatatcct
     9421 tttaactgtc gata
//
LOCUS       DAFTHM010000099         9406 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFTHM010000099 DAFTHM010000000
VERSION     DAFTHM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.099"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            94..1248
                     /locus_tag="L7C88_002315"
     CDS             94..1248
                     /locus_tag="L7C88_002315"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBP9559117.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            complement(1270..2022)
                     /locus_tag="L7C88_002316"
     CDS             complement(1270..2022)
                     /locus_tag="L7C88_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBP9559118.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(2386..5052)
                     /locus_tag="L7C88_002317"
     CDS             complement(2386..5052)
                     /locus_tag="L7C88_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBP9559119.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5393..6844
                     /gene="cls"
                     /locus_tag="L7C88_002318"
     CDS             5393..6844
                     /gene="cls"
                     /locus_tag="L7C88_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBP9559120.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            complement(7173..7988)
                     /gene="thiD"
                     /locus_tag="L7C88_002319"
     CDS             complement(7173..7988)
                     /gene="thiD"
                     /locus_tag="L7C88_002319"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBP9559121.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            8282..8557
                     /locus_tag="L7C88_002320"
     CDS             8282..8557
                     /locus_tag="L7C88_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559122.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            8984..>9406
                     /locus_tag="L7C88_002321"
     CDS             8984..>9406
                     /locus_tag="L7C88_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBP9559123.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTD"
BASE COUNT         2835 a         1909 c         1638 g         3024 t
ORIGIN      
        1 aatccttaaa tattctcttt tttatatttc ttttaatctt tttatgatac cttagtaaag
       61 taagtttttt atcataagta aagaggtgtt gaaatgaaaa tagggattga tcgtctttcc
      121 ttttttattc ctaatttata tttagatatg acagagttgg cagaaagccg tggggatgat
      181 cctgcaaaat accatatagg gattggtcaa gaccaaatgg cagtcaatcg tgcaaatgaa
      241 gacatcatta cactaggagc aaatgctgcc agcaaaatcg taacagaaaa agaccgtgag
      301 ctaatcgaca tggtcatcgt cggaacagaa tccgggattg atcattcaaa agcgagtgcg
      361 gtaattatcc accatttact gaaaatccaa tcttttgctc gttcttttga agtaaaagag
      421 gcttgctacg gtggcaccgc agctttgcac atggcgaaag aatatgtcaa aaatcatcca
      481 gaacgaaaag tactagtcat agcaagtgat attgctcgtt acggcttggc aagcggtggt
      541 gaagtgacgc aaggtgtcgg tgctgttgcg atgatgatca ctcaaaaccc gcgtatttta
      601 tcgattgaag acgacagcgt atttctgaca gaagatatct atgatttctg gcgtccagat
      661 tatagcgaat ttcctgttgt tgatggtcct ttatctaatt ctacgtatat cgaatcattc
      721 caaaaagttt ggaatcgaca taaagaattg tcgggtcgag gactcgaaga ttatcaggcg
      781 attgctttcc atattccgta tactaagatg ggaaaaaagg cattgcaaag cgtattagac
      841 caaacagacg aagaaaatca ggaacgtctt atggctcgct atgaagaaag catccgttac
      901 agccgacgaa tcggtaatct ttacactggt tcattatacc tggggctaac ttctctactg
      961 gaaaattcga aatcactaca gccaggagat cgcatcggtc tattcagcta cggttctggt
     1021 gcagtaagtg aattttttac aggttatctg gaagaaaact atcaagaata tctcttcgca
     1081 caatctcatc aagagatgct agattctcga acacggatca ctgttgacga atatgaaacg
     1141 attttcagtg agacgcttcc tgaacacgga gaatgtgcag aatatacttc agatgtacct
     1201 ttttcgatta caaagatcga aaatgatatt cgttactaca aaatataata aaatcataaa
     1261 aagaaccctt cacgagtcgt gaaaggttct ttttttatct gcggaccaaa ggagcagtct
     1321 ataggtcagc ttagtcgtac taaggatttc tcgtttttca ctgaatagtt tgcgaatgta
     1381 cctggtcaca acaggatctt ttgcgtacgc gtcatagtat agcttcatca attcttcagt
     1441 aattgattcc tgtgtaaaat aagtaaaatc ttttttcttc actttgaatc cttcatcaat
     1501 taagtatgtt tcaaattgat ccattacaac tggcgatgta ttaggatctt cttctatcat
     1561 tcctagttgc ttttcgatag gataaaaaac atcatcgatt gattccacta ctctgattat
     1621 cacgcaccat ttgcttgact ttttcatcaa tttttctaat tgaataagat gtaccaatgc
     1681 tggatttgct gctgtaaaaa ccatttcata tgtctcattt gattggataa attcttctaa
     1741 cgactgtttg ataaaggaaa catttggcaa ctcatttttt tctgcttctt tttttgcatt
     1801 ttctagcatt cctgaagaaa aatcgatcaa atcatagcga ttaatttctt ttgctaagga
     1861 aagaaatctg ccagatcctc cagcaacgtc tgctgctgtt tcagcaggca ggactttctc
     1921 cgttttcaga taatttttta catcttcagc aatagttact tgcgattctt gctggatttc
     1981 ataatattct tcagcaaatt catcccattc tttttcattc atttgatttc ctctaatttt
     2041 ttgttatatg ttttcacttt tcggaataaa tcattctcct cttttatcta ttctatctct
     2101 tttgatgaat aataaaatga ttggctttcc gtctatcata aataaaaaaa gggactgtga
     2161 ccaaagtcgt gtcaaagtcc ctctttccga ataaacagtg tccaatcaga tgaccctcag
     2221 tattagctca aaatgctgat tttacaactt cttccttaaa cggtgttctc ctgccaactc
     2281 ttcggtcaca agtcacaata ttcaacaaac atgagaagct gtttgttgaa attgcacctt
     2341 gtgactcaga attaaacggc aggctcacaa cctcgttgat tcgttttatt tatttccttg
     2401 tactcgtaca atgatcaatt tagtgatttc catcaaaaca attgtcacaa gtgcgattcc
     2461 catacatgta aagacttctg tcaatccaaa tgctgatggg atagagaaga cttctttcag
     2521 tcctgggatc attgttaagc agtaaagcgc gctacataca actacagcta gtaagacact
     2581 tctgttagag aagaaccctg cttggatagc tgtttgtgtg tttgaacgtg ctgggaatgt
     2641 ttgcaatgtc cgacaccaaa tcaatgttga aaatgacatg gctacaccga attcaggtga
     2701 atgctgcatg ccaagccatt gagcaaagat aacagcaatc ccaatcagca caccacgata
     2761 cgttacagaa atcaatgttt tgtccgtaaa gattcctgaa tttggatctc ttggcgggcg
     2821 gttcatcgta gcaggttcag ctttttctgt acctaatgca attgctggca gtgaatcatt
     2881 gactaaattg atgaacaaca gttgtaatgc tgtaaatgga ttggaccagt cagcaactaa
     2941 ggcaaagatg atcgcaatga tcgcacctaa atttcctgca aatagataag aaatagcttt
     3001 cttgatatta tcaaacacat tacgtcctac ttctactgcg ctgacaatag aagcaaagtt
     3061 atcatccgtc aataccatcg ctgctgcatc ttttgccaca tctgtacccg ttcccatagc
     3121 aattccgatg tctgcttgtt tcaatgctgg tgcgtcattt acaccatcac ctgtcatagc
     3181 tgagatatga cctttatttt gccaagcacg aacgatacga attttattct caggtgaaac
     3241 acgtgcataa acagtgactt tttctaaaac ttcgtttagt tgatcttctg tcaattcatc
     3301 tagttccgtc ccggtcaaag ccaggtttcc ttcttcaaaa atcccgattt gttttgcgat
     3361 agcaacagct gttgttttgt ggtcaccagt aatcatgatt gttttgattc ctgcacttct
     3421 tgcttctgtt accgcctgag tcacttcagc acgtggagga tcgatcatag caagcaaacc
     3481 aacaaggatc aaatcgtctt catcttcaaa tgataaatca aaattatcaa gtggacggta
     3541 agcaaaagct agtacacgta atgcgcgtgt tgaaaaagct tcattttgct cttggaattt
     3601 tttcatcaat tcatccgtca tcggaacgac ttcaccattt agcaatactt ttttactgcg
     3661 ttggaagacg atatctggtc cgcctttaac aaacaagtaa tttttgttat caattgtgtg
     3721 tccagtagac attaattttc gatctgagtc aaaaggaagt tctgcttgtc ttgggtagtt
     3781 gtttcggatt tcctgataag gctggtttaa tttttcacta aagtcgataa acgctacttc
     3841 cgtagggtcg cccaatttag taccgtcttc actgatcgat gcatcattcg ctaaaacact
     3901 gatttcgatc aagcgacgtt cgtcagctgt ccattttgaa gggtcatttg tgaaatcccc
     3961 agtatcgcca ttacctaaaa agtagtcaac aactgtcatt ttgttttgtg tcaatgtacc
     4021 agtcttatct gtacagatga tacttgtcga accaagtgtt tcaactgctg gaagcttccg
     4081 aataatggca tgacgttttg ccattttatt cgttcccaaa gataacacga ttgttacgat
     4141 agactgtaat gcttctggaa tagcagctac ggctacggct acggcaaaca tcactgcgct
     4201 gacgatatct gcagtcatat ctcctgtacc ttctccaaga taaatacgaa acagttggat
     4261 acctaaaatc aataaagaca atgccaaaat agccaaactt agttttttac tgaatttatc
     4321 cagacctcgt tgtaacggag tgacttgctc agttgttgat tccaaaaggc cagcaacttg
     4381 tccgatctcc gtattattcc cagttgaagt cactaagaat ttaccgcgtc cgtaagttac
     4441 gatcgttcca ctgaatacca tatttgtacg atctccgatt ggtaccgtac ttgtgatatc
     4501 cgttacttct ttttctgcag aagtcgactc tcctgtcagc ataccttcat ctacttttaa
     4561 tgatcccgca tctagtaaac gtccatcagc aggtacataa tcgcctgcgt ctaacaacac
     4621 gatatctcct accacaagtt cgtttgccgg aatcgttttt tccttaccat cacgaatcac
     4681 tcgagcatcg ggcgctgaaa ggtttttcaa cgcttctaaa gaaccttctg ctttttttgt
     4741 ttggacaaca ctgattatag aattcaacat caatactgca aaaataacta agaattcgat
     4801 gtagtcaccc atgaccatct gaatcagtgc gacaatcagc aatacgataa ccattgcatc
     4861 tttgaaagtt tctaagaaca atttccaagt tggcttcttc ggcttttctt ttagctggtt
     4921 caagccatct ctttctaatt tttccttcgc ttgcgtggtg ctcaatccat cggttgagct
     4981 ctgcgtttgc tgcatcaacg agtcgatcgt ttctttatag accgcttgtt gtgcttgttc
     5041 cttgttttcc aaatttcatc ccccattttt tgatcttggc cctagtcctg tctgaaaaaa
     5101 aagagaccta agacaaatac gcatttgtct taggtctcac catttcatac aataccagaa
     5161 aaccatttgg ttaacttact gttgatatta tcgcaacaaa cgttgccggt tactccccta
     5221 aggagatatt caactgtact aatatcctac cttattaacc tacaaaaagc aactacttta
     5281 gcccgattta cctacatttt catgaaagga gtgaaaagta tattcacctt ggtaggcttc
     5341 tttcttctat catgctatac taatgttatt gtatgtaagg aggaacattt ttgtggtatc
     5401 tagtattata accgcccttt atctattaaa tgcacttatt gctttggtgg ctattttgat
     5461 caaaccccga gatgtagcag ccatttgggc atggctctta gtattgtttg cccttcctgg
     5521 ggtgggcttt gtattatatt tatttttcgg acgtggatta acggataaga aaaaattcta
     5581 tctccgacaa agtgacttga aagaattaga aaactttcag tcttttagag gagataccat
     5641 tgaacattac gatcctgaca tgggcgataa agacaaacag caatttgttg acttcttctc
     5701 ttcattaaat cgtatgccgc tgacaagaat gaattctgtc actcttctca cagacggaca
     5761 agagaaattg gattcactgc ttcaagatct aaaaaaagcc aaacattcga tccatatcga
     5821 atattacgca tttgtgacag ataatatcgg ccagcaagtc ttacatgttt tagaagaaaa
     5881 agccgcagaa ggcgtggaag ttcgaatatt atatgatgca tttggctctc atggcacaaa
     5941 agcaaaagat ttcaatcgtc taatcaaaaa tggtggacat gtccatacat ttgttacctc
     6001 acaaagggca ttacttcgtt tccgattgaa ttaccatgat caccgaaaaa tcgttgtgat
     6061 cgatggaaag attagttata ccggtggttt caatattgcc aatcaatatg taaatacaac
     6121 aaaaaaattc ggctattggc gcgatacgca tatacggatt ttcggtgccg cttcttcttt
     6181 gctccagctt cgcttcttaa cagactggaa cgtctcggta cctgaagaaa aaaaggtcgg
     6241 ctatcatttg aattatttct ttaaaaaagc agatcgagat gaatctaagc ttgctgatac
     6301 atccatccag cttgtttcaa gcggaccgaa taacgaaagg gaacaaatca agctttcatt
     6361 tatcaaattg attacttctg ctaaaaaacg tgtttggata cagacacctt accttgttcc
     6421 tgatgaaagt gtcattgctg ctttaaaaat cgcaactgcc tctggtgtag atgtgaaaat
     6481 catgattccc aacaaaccgg atcatccttt tatttatcga gcaacacaat attatgctcg
     6541 gcagctgatc aaggaaaatg tacaaatcct tgtctatgag aacggcttcc tccatgcaaa
     6601 aacattgata atggatgatg aaatctgcat ggtaggttca gcaaatcaag atattcgtag
     6661 ctaccgattg aattttgaaa caagtgctgt catttacgat cctgagtttt tagaagaact
     6721 tgctactcag ttcaaagaag atgagacaca ttgttcatcc atgacaactg aaacagtcaa
     6781 ggaaatgtct aactggctat tattcaagca acaaatttct cgattatttt ctccaatcct
     6841 ataatttttt tattcaagta gagaaaaata tactaagatt aaagggactg tgacaaaaat
     6901 cttgtcacag tcccttcttc cgaacaaacg gtgttctcct gccaactcct cggtcacaag
     6961 tcacaatatt caacaaacat gagaagctgt tttttgaact tgttccttgt gactcggagc
     7021 tggacggcag gctcacgacc tctttcttaa acggtgttca aaagcttgca tctgcggtaa
     7081 taagtccaac caagttaaaa acataagaag ctgtttttac ttggctgttc ttattacttg
     7141 atgcagggca actttttcac aacttctttc ttttactcta attcaccagc tgcccaatga
     7201 ttgatggggc catatttgtg ccctacattt atttcttcac gaattgcacg gtttacatag
     7261 tcttttgcca atcggatcgc ttgttcaact gtttttcctt tcgctaactc agctgcaata
     7321 catgcagata gcgaatcgcc agttccgttg atccggtcgg taggataaaa tggtgcattt
     7381 aaccaaaatg attttcctga ttcgaacaat acgtagtcat tgactgtttc ttgctgcgca
     7441 tttttagcat gatgtccttt gatcataacg ttttttgcac ccatatcttg cagttctttt
     7501 gctgcttgca caaaatcttc ttcagctgct aatgtccgtc cagtcagctt ttctgcttca
     7561 taaaaattag gtgtcagtac ttcggccaaa gggacaagct tttctttcaa gctttgcaaa
     7621 gcagattctt ctagtaaaag atttccatgt ttcgttacga ttacgggatc cacgactaat
     7681 ggtccaaaat catatttttg gtaatttttt acaactgtct caatcaactt tgaatctgct
     7741 agcatacctg ttttagctgc acgtatttga aagtccttcg caatcagttc aaattctttg
     7801 tcgataaaat ctgttggcaa tgtcacactt gctccgattc cgtaagaatt acctgcaaca
     7861 catgcggtca tgacagaaac accgtaaaca tttcttgtaa agaatgtatg catatctgct
     7921 tgcatccctg cgcttccatc gctatctgat cctgcgatcg tcattgcttg tacatactga
     7981 tcttccatca aatcgattcc tccattttta taaaaagatt tttcataata ctgttactgt
     8041 ttctatcata tgtttttcaa agtatccctc agtaaatata ccactacctt ttcttggtaa
     8101 tcaaatttat ttgaaaaaac atttgcaata aatcagaaaa tagtggtcgt ttatttgtat
     8161 tcgctattct aataataaat aaccactatt tgatttatat atatttcagt atccttcttg
     8221 ttttcatata accaaaggcg ctatgatttc catatgaaaa aaataaagtc aggtgaaaaa
     8281 aatgaaactt gaggataaaa aagtcatttt gaagaaaatc aaacgactac cagaccaaat
     8341 agatggctat acgatctgtt ctttcaaaaa agacaggagt ataaaagctt atacgcaaaa
     8401 cacagaaaaa ggaataatct atttcctaca tgaagaaggt tacgataccc aaacctttat
     8461 gtttactgaa aaaaaagaat ttcataaaca gatgaaaaaa ctgattgaaa aagaatttcc
     8521 aagaagtcat aaactctatg tgaatcagca attttaactt ctaactgttc tttattaatt
     8581 aaaaatgttc tgtaataaaa taaaacttta taacaactat aacaaaaccg aatgcaaaac
     8641 agaagttcta taagttataa tcatagttgt taggtgattc atctagtaaa aacaccagat
     8701 ttcaaatttc acacaattta aactagatca atcatcaacc ttcttcaaat tgttagaacc
     8761 ctttcccgag gagctgcagc ataagcaaaa aaacaaacag gaagccaaat ggctaagaca
     8821 ttttttctat tagtctagtt gtttctcgtc gcaagtttaa gactttagaa agttatttct
     8881 aatgatgttt gggttgtttt gatcaatgct tatgcacagc tccttaccta ttatttatct
     8941 caacagatct aacaaattaa tggactattt aaggagtttt tttatgctta cgatctattc
     9001 ttctcgcaca catagttacc atctgatggc aaactggctg aaagaccatc aaatgcctta
     9061 cagagaacga attttcacac ctaaacagcc tttaacaagg aaagagatat tttatttatt
     9121 gtcattaaca gaaaacggat ttgacgatct attagctaaa cgctcgattg attataaaaa
     9181 tttgaaagac caaatcgacc aatgtacgac ctcagagctt gtcgatctga tcgtctcgca
     9241 ttttactttg ttacaacgtc ccatcattac tgacggaaag aaattattag tcggattcaa
     9301 tgaagatagc atgcgtcttt ttatccctgt acaatggcgc agaagtcaac tgaaatctgt
     9361 ctataacgat tttacatggg taagcaatct agaaaattct acggat
//
LOCUS       DAFTHM010000100         9380 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFTHM010000100 DAFTHM010000000
VERSION     DAFTHM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.100"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            11..499
                     /gene="purE"
                     /locus_tag="L7C88_002322"
     CDS             11..499
                     /gene="purE"
                     /locus_tag="L7C88_002322"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBP9559124.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            492..1616
                     /gene="purK"
                     /locus_tag="L7C88_002323"
     CDS             492..1616
                     /gene="purK"
                     /locus_tag="L7C88_002323"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBP9559125.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            1629..2924
                     /gene="purB"
                     /locus_tag="L7C88_002324"
     CDS             1629..2924
                     /gene="purB"
                     /locus_tag="L7C88_002324"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBP9559126.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(3104..3481)
                     /locus_tag="L7C88_002325"
     CDS             complement(3104..3481)
                     /locus_tag="L7C88_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559127.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            3737..4465
                     /locus_tag="L7C88_002326"
     CDS             3737..4465
                     /locus_tag="L7C88_002326"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBP9559128.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            4465..4719
                     /gene="purS"
                     /locus_tag="L7C88_002327"
     CDS             4465..4719
                     /gene="purS"
                     /locus_tag="L7C88_002327"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBP9559129.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            4721..5392
                     /gene="purQ"
                     /locus_tag="L7C88_002328"
     CDS             4721..5392
                     /gene="purQ"
                     /locus_tag="L7C88_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBP9559130.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            5393..7615
                     /gene="purL"
                     /locus_tag="L7C88_002329"
     CDS             5393..7615
                     /gene="purL"
                     /locus_tag="L7C88_002329"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBP9559131.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            7600..9039
                     /locus_tag="L7C88_002330"
     CDS             7600..9039
                     /locus_tag="L7C88_002330"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBP9559132.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            9071..>9380
                     /locus_tag="L7C88_002331"
     CDS             9071..>9380
                     /locus_tag="L7C88_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBP9559133.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     L"
BASE COUNT         3041 a         1615 c         2211 g         2513 t
ORIGIN      
        1 aggaaaaaca atgacagcaa aaatctctgt gattatgggg agtacttcag attgggaaac
       61 aatgaaagaa gcatgtcaaa tattggatga attcggtgtg tcttatgaaa aaaaggtcgt
      121 ttctgctcat cgaaccccag atttgatgtt tgaatatgca caaaacgctc gaaaaaaagg
      181 aatcaaaatc attattgcag gagcaggggg agccgcgcat ctgccgggta tggtcgcatc
      241 aaaaacaact ttgccggtta tcggtgtacc ggtccaatca cgaacattaa atggtttgga
      301 ttcgcttctt tcgattgtcc aaatgcctgg aggagtacct gtagctacta cagcaatcgg
      361 aaaagcggga gcaattaatg ctggactact tgcgatacag atgctttcca tgtatgattt
      421 agaattggag gctaaattgg ctgaaagacg ttcaatgttg gctaaaactg ttatagaaag
      481 tagtgatcaa cttggttaaa cctttgttgc ctggttcaac gatcgggatc gtcggtggcg
      541 gtcaattagg tcgtatgatg gcgattagtg caaaagaaat gggctttaaa gtaggtgtgc
      601 tggatcctgt gagcgattgt ccagccgcac aagttgcaga ttggcacatt gaaagtgtct
      661 atgatgacac ctttgcgctg aaagagcttg ccagaagaac agatgtcatt acctatgaat
      721 tcgaaaacgt cagtgtagag gcgttaaatg cgattttacc catgtcattt attcctcaag
      781 ggacagactt gcttgcgatt acgcaagacc gcctgttaga aaaatctttt ttggaaacga
      841 ataacatcgt gattgctcct tatgcaacga tcgtcagtcc gacggatatc caagatgcga
      901 ttgacgggat cggctatcct tgtgttttga aaaccactcg aggcggctat gatggcaagg
      961 ggcagtatgt tttgaaaagt cgggcggatc tagctcctgc catggacctt ttaagagaag
     1021 gaacctgtgt tttagaagca tggatcccgt ttgaaaaaga gatttcgatc atggtggcag
     1081 gaaatggtca aggagatttc acgacttttc cggtcgtgga aaacatccac cacaacaata
     1141 ttcttcatga aacgattgct ccagccgcga ttgatcagga tgtgatcgag gaggctgagc
     1201 gtattgcccg tgtgattgca gaagcagtga gcctttcagg tgttttaggg gtagaaatgt
     1261 ttttaacaaa aacaggcggg ctatatgtga atgaattagc tcctcgtcct cacaattctg
     1321 gacattattc tattgaagct tgttctatga gtcagttcga tgcccatatt cgaggtattt
     1381 gtggttggcc attaggagaa aaagtacgtt tgataagcaa tgcagtaatg gtcaatgttt
     1441 tgggagaaca actgctggaa agctatcgct tgattgagaa taagccagac tggcaattcc
     1501 atttctatgg aaaaaaacaa gcaaaaaaag gtcgcaagat gggacatatc actatcttga
     1561 cagaagacat ccagcaaacg ctggaagaaa tcaaacaaac gaatatttgg gattagagga
     1621 gaaaaaacat gttagaacgt tatacacgcc ctgaaatggg gaatatctgg acggaagaga
     1681 acaaataccg tgcgtggctc gaagtcgaga ttttagcaga tgaagcttgg gcagaacttg
     1741 gtgaaatccc gcaagaagat gtgaaaaaaa ttcgtgagca tgcatcattt gatatcgatc
     1801 ggatcttgga aatcgaaaaa ttaacacgcc atgatgtcgt tgcgtttaca cgagcggttt
     1861 ctgaaacatt gggagaagaa agaaaatggg tccattatgg tctaacaagt acggatgtcg
     1921 tagatactgc ttatggctat ctcatcaagc aagcaaatga tattttacgg gaagacttga
     1981 aacgttttac ggaaatcatt ggcgaaaaag caaaagaaca caaatataca gtgatgatgg
     2041 gtcggacaca cggtgtccat gctgaaccaa ctacttttgg attgaaactt gccacatggt
     2101 attcagaaat gaaacggaac atcgaacgat ttgaacatgc ggcaaaagga gtagaagcag
     2161 gaaaaatctc aggagcagtg ggaacgttcg caaatatccc gccatttatt gaagagtatg
     2221 tatgtaaaca attggggatc cgtccacaag aaatctctac tcaagttctc cctcgggatc
     2281 tacatgctga atatttctca gcgatggcgc ttattgctac aagtattgaa cgttttgcaa
     2341 cagagatacg cggattgcaa aaatccgaaa cacgtgaagt agaagaattt tttgcgaaag
     2401 gtcaaaaagg ttcttctgct atgccgcaca aaaggaatcc gatcggttca gaaaatatgg
     2461 ctggtctagc cagagtggtg cgcggacaca tggtcactgc ctatgaaaat gtcacattat
     2521 ggcatgaaag agatatttct cattcttcag cagaacgaat catcttgcct gataccacga
     2581 ttttattgaa ttacatgtta aatcgttttg gcaatatcgt taaaaatcta acggtctttc
     2641 ctgaaaacat gaagcggaat atgtctgcaa catttggttt gatttatagc cagcgcgtta
     2701 tgctgaaatt gatcgataag ggaatgacaa gagaagaagc ttatgatctt gttcagccaa
     2761 aaactgcgta cgcttgggac aaccaagtgc agttccgccc gctgttagaa gaagatccaa
     2821 ccatcacatc ggtattatct aaagaagaaa tagacgatgc ctttgattat catcatcatt
     2881 tgaaaaacgt tgacgtgata ttcaaacgag taggtttgga ataaagaaga gtgagttgca
     2941 aaattcaatt aaaatagaat agcaaaaata accaaaaaag aagcagatcc gttagcggtt
     3001 ctgcttcttt tagtttatta tattttctta tcaataatag gaacctgatt ttaaaagcgg
     3061 ctacctcttt accgtgcctc tttacataca aaaaatagag gaattaagcg taaatggctt
     3121 ggctattata actaaaatgc tggttatgga gatgttgcag caagttttcg agaaaagcgt
     3181 attccatctc ttgtccattg aataagatct ggatacgata atgatttttg aaacgcttct
     3241 gttcatgaat ctgactgatt gaaagttcgc ctttgtgttc tgtctgataa agaaaagtcc
     3301 ttttacggca ttcagcacag cgcttggttg ctcggcggat ttttcggaat gtataaaaac
     3361 tagtatcttt attgcataaa taaacgtctt tgatcgacag caaatcatta tatagacagg
     3421 aacgttcttc agctgttaat tctgataaaa aaagctgacc ttgttttatt gcatcttcca
     3481 tcggcaagtg cctcctcgaa cccattatcc aaatttttag ttaattctaa tataccatca
     3541 ttaagtataa atgtaaacgc ttgttgatgg tataagattt tcgtttctga taaaacacga
     3601 acattaaaag aatctaatgc cttaaatgta catatttttg ttgatttata aaaagatgat
     3661 tgctaaaatt taaagtgaaa aaacgaacaa aaaacgatgt atttgctttt aatgtaaata
     3721 aaaaggagag acgtacatgg agaagaaaga acttttgtat gaaggaaaag ccaaaaaaat
     3781 atatcttact tctgatgaga acttgatttg gatagaatat ttagatcaag caactgcgtt
     3841 gaatggcgcg aggaaagacc agataagtgg aaaaggagaa ttgaataatc aaatcacaag
     3901 tgcaattttc cgttatctga ctcaaagagg aataaaaaat cattttattg aacaattgtc
     3961 taaaaccgaa caattagcaa aaaaagtaca aattatccct ctggaagtgg ttatccgaaa
     4021 tattgcagca ggaagtttct caaaacgtct aggtgttccc gaaggtaaag aattcatcaa
     4081 accaatcatt gaattctact ataaggatga ccagttggat gatccattta tcaatgaaga
     4141 gcatatctat ttcttacaac ttgcaaaacc ggaagaaatc agtgagctga aagcccaagc
     4201 gttggctatt aatgaaattt tgaccgaatt atttgctaag gtcggtttgg ttttagtaga
     4261 tttcaagcta gaatttggcc ggtcgaatgg acaaattttg cttgcggatg aagtaacacc
     4321 ggatacttgc cgattatggg atgaacgtac gaatgaacat atggacaaag acgtttaccg
     4381 cagagatcta ggtgatttga tcccagtcta tcaagaagta tataaccgtc tatcggaact
     4441 aactgaagaa aaggagcgag tatgatgtat ttcgtaaaag tatatgtaac ctataaagat
     4501 tcagtgttag atcctcaagg ggaggcagta aaaaaagcag tccatcgtat gggatatgaa
     4561 acaatcgaag atatccgaat aggaaaatac tttgagatac aacttgctga tgcagaagaa
     4621 ccaatcgata cagtgattga aacgatttgt gacaagctgc ttgcaaatgt aaatatggaa
     4681 acataccgat atgaaatcaa aaaaatggag gaagtataac atgaaatttg cggtcatcgt
     4741 ttttccaggt tcaaattgtg acgcagatat gttatgggca gttcgcgaga tcatgggcgc
     4801 tgatgccgaa tttgtacggc atgatgagtc ctctttagaa ggatttgatg gggttttact
     4861 gccgggagga ttctcctatg gtgactattt gagatgcggt gcgattgctc ggttttctac
     4921 aatcatggaa gaagtgattc gttttgctga agaagggaaa ccagtattcg gtacatgcaa
     4981 tggattccag atattgacag aagcaggact tttgccaggt gtactgagac gaaatgagtc
     5041 tttgcatttt atttgcaaaa ctgtaccatt gaaagtcaac cccaagacgg cctttacttc
     5101 agagtatgaa gccgacgaaa taatctatct tccagttgct catggggaag gaaattattt
     5161 ctgtgacgaa gaaacacttc aagaactaaa aaaaaataat cagattgcct ttacttataa
     5221 tgacaacatc aacggcagcg tggaaaacat tgcagggatt acgaacaaag cagggaatgt
     5281 gttaggaatg atgcctcatc cagaacgtgc agtagaagac ttgctaggat cagaagatgg
     5341 gaaacggttc tttgcttcca ttttaaaaaa cttcggaaag gtgaccgtat agatgaaaac
     5401 attgaaagaa ccgacagctg aagagatcaa gaaaaaaaga atctatgccg aatggggatt
     5461 gactgatgaa gaatatcgaa tgatcgaaga agatatctta ggaagaatgc ctaattatac
     5521 ggaaactgga ctgttttctg ttatgtggag cgaacattgt tcctataaaa attctaaacc
     5581 ggttctacgc aaatttccta ctagtggacc tcatgtgttg caaggccctg gagaaggcgc
     5641 aggcatcgtc gacatcggtg atggactagc agttgtcttc aaagcagaaa gtcacaatca
     5701 tccttcagcc gtggagcctt atgaaggagc tgcgacagga gttggcggaa tcatcagaga
     5761 tattttcagc atgggggctc gtccaattgc gttgctagat tcattgaggt tcggcgaatt
     5821 agataatcca agaacgaaat atttactaga agaagtagtt gcaggtatcg gcggatacgg
     5881 caattgtatc ggcataccga ctgtaggcgg cgaaattgca tttgatcctt gttatgaagg
     5941 aaacccatta gtcaatgcaa tgtgcgtagg tttgattgaa cacaaacata tccagaaagg
     6001 gcaagccgct ggcgtcggta attcgatcat gtatgtaggt gcaaaaacag gtcgcgacgg
     6061 tatccacgga gcaacttttg cctcagaaga atttaatcaa gaagaagaac agcaacgttc
     6121 tgctgtacaa gtaggcgatc cttttatgga aaagctgctg cttgaagcgt gtttggaatt
     6181 aatcttgcat cattcggatt ctctaatagg tatacaggat atgggagcag caggacttgt
     6241 ttcatctagt gcggaaatgg cttcaaaagc tggctcagga cttatattga cattagatga
     6301 agtcccacaa agagaaactg ggatgacacc ttatgaaatg atgttatcgg aatcacaaga
     6361 acggatgttg atttgtgtta aatcaggaga ggaagaaaaa atccaagaac tatttcagaa
     6421 gtatgatcta gatgcagtca ctatcggtaa agtaacagac gacgggcaat atcggctata
     6481 tcatcaagga gaagaagtag caaatctgcc agtcgatgca ttagctgaag atgcaccagt
     6541 ttatcataaa gaaatgaaag aaccagctcg aatcgtagaa tttcagcagt tagctcctta
     6601 tcagccagtt atcgaagaac ctggacaagt attgcttgat ctgctgcagc aaccgacgat
     6661 tgcttcaaaa cgttcaatct acgaaactta tgattcacaa gtacaaacca atacagttgt
     6721 ccgtccagga agcgatgctg ctgtgatgag ggttagaggg acgaataaag cgttagctat
     6781 gaccacagac tgcaacgcgc gctatctgta tttggatcca aaaatcggag gacaaatagc
     6841 agtggcagaa gctgctagaa atattattgc tagcggtggt aagcccttgg cgatcaccga
     6901 ctgcctgaac tatggttctc ctgataaacc agaagttttt tgggaattat cgacttcagc
     6961 tgacggaatt gctgctgcgt gtgaaacgtt aggaactcct gttatttcag gaaatgtctc
     7021 tttatataat gaaacggatg gtcaagcaat ctatccaaca ccaatgattg gtatggtcgg
     7081 attgattgag gatcataaac atatcactac tcaggaattc aaaaaatcag gggatctaat
     7141 ctatatatta ggtaagacgt ttgcagattt tgatggcagt gaattacaaa agatgcagct
     7201 tggaagaatc gaaggtgtga tccgaaactt tgatctatcc attgaaaaga gaaaccaaga
     7261 gttagtattg acagccatcc aaaacggatt gattgaaagt gctcatgact gttcagaagg
     7321 tggcttggca attgcactgg cagaatcagc tttcaaacat cagctaggga tatctgtaca
     7381 gtttgaattg tcctctgctc aattatttgc agaaactcaa tcaagatttg tgttgacagt
     7441 cgcaccggaa aataagacac gattcgaaga aatgatggga gatgctgctg ttttagcagg
     7501 taaggtgacg gatgaagcga taatcgaaat ttcagcaact gacggtcaga tcaaaataga
     7561 aactgcagta gcaagaaagt gctgggagga tgcaatcgta tgtcttatga agtgaagagt
     7621 ttaaatgaag aatgcgggat cttcggtgtt tggggtcatc cagacgccgc tagtgtggca
     7681 tacttcgggc tccatagtct tcagcatcga ggacaagaag gtgcaggtat cgtgtccaat
     7741 gatcgaggaa agcttaaggg gcatcgagat ttggggctgc tttctgaggt attcaaagat
     7801 caaagaaaat tgcagcagtt aacaggagaa gctgcaatcg gacatgtacg ttatgcaaca
     7861 gcaggcaatg gaagtgtgga caatattcag ccttttctat tcaaatttca tgatcagtcg
     7921 atcggcttag cgcataatgg taacttgatc aatgctcgtt cccttagaaa agagttagag
     7981 gaaaatgggg cgatcttcca ttctaactcc gatacggaga tattgatgca tttgatccga
     8041 cgaagtgaag aaacagattt tttaaataaa ttaaaaagtg ctttgaatga agtcaaaggt
     8101 ggctttgcct atttattaat gacagaaacg gcaatgattg ccgctttgga cccaaatggt
     8161 tttcgtccat tagcaatcgg acaaatgaaa aacggagcat acgtgattgc ctcggaaact
     8221 tgtgcattag aagttattgg ggcacgtttt ataagagatg tccagcctgg tgagatagtg
     8281 atcatcaatg acgaaggaat ccagattgat tgctttacga aggacacgca gctttctatt
     8341 tgttcgatgg aatatatcta ttttgccaga ccagattcaa acatcgcagg gatcaatgtg
     8401 catactgcac ggaaaaatat gggacggaat ttagcgaaag aatcgccagt aaaagcagat
     8461 atggtcgttg gcgtacctaa ttcttctttg tcagccgcaa gcggttatgc ggaagctagt
     8521 ggaatccctt atgaaatcgg attagtaaaa aatcaataca ttgcccgaac atttatccag
     8581 ccaacgcctg agctaagaga gcaaggtgtt cgaatgaaat tatctgctgt acgaggagta
     8641 gtggaaggta aaaaggtgat tatggtcgat gattcaattg ttcggggtac gacaagcaga
     8701 cggatcgtcc atcttttgaa agaagcaggg gcaaaagaag tccatgtgag gattgcttct
     8761 cctcctttga aatatccatg tttttacggg attgatattc aaacgcgtaa agaactcatt
     8821 gcggcaaatc acacgattga tgaaatcaaa gaatgtatcg gtgcagattc tttaggtttt
     8881 ttaagtgaag agggtctgat cgaatcgatc ggtctggaaa aagatgctcc gtattcagga
     8941 ttgtgtatgg cttatttcaa cggagattat ccgacgccgt tatatgacta tgaagaaaaa
     9001 tatcaggaat cactaaaaga aaaagtatcg ttcttttaaa agcagaccaa gaagggagta
     9061 tatgaattca atggcaaatg catacgcaaa agctggcgta gatgtcgaag ctggatatga
     9121 agtagtagaa cggatcaaga agcatgtcaa aaaaacggaa cgtttaggta tgatgggcgc
     9181 tataggagga ttcggcggtt gttttgattt atcggtcttt caattaaaag agccagtcct
     9241 tgtctcgggg accgatggcg tggggacgaa attagcagtg gcaatcgaag cagacaaaca
     9301 cgatacaatc gggatcgact gcgtagcgat gtgtgtcaat gatatcttag cacaaggcgc
     9361 agagccgtta tatttcttag
//
LOCUS       DAFTHM010000101         8983 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFTHM010000101 DAFTHM010000000
VERSION     DAFTHM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.101"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            2..369
                     /locus_tag="L7C88_002332"
                     /pseudo
     CDS             2..369
                     /locus_tag="L7C88_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            549..1490
                     /locus_tag="L7C88_002333"
     CDS             549..1490
                     /locus_tag="L7C88_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBP9559134.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="L7C88_002334"
     CDS             1559..2290
                     /locus_tag="L7C88_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBP9559135.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="L7C88_002335"
     CDS             2434..4614
                     /locus_tag="L7C88_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBP9559136.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..5116
                     /locus_tag="L7C88_002336"
     CDS             4634..5116
                     /locus_tag="L7C88_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBP9559137.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5132..5893
                     /locus_tag="L7C88_002337"
     CDS             5132..5893
                     /locus_tag="L7C88_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBP9559138.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6024..7358
                     /locus_tag="L7C88_002338"
     CDS             6024..7358
                     /locus_tag="L7C88_002338"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBP9559139.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7786..8271
                     /locus_tag="L7C88_002339"
     CDS             7786..8271
                     /locus_tag="L7C88_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBP9559140.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8264..8947
                     /locus_tag="L7C88_002340"
     CDS             8264..8947
                     /locus_tag="L7C88_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBP9559141.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
BASE COUNT         2961 a         1568 c         1971 g         2483 t
ORIGIN      
        1 gatgtttacg aatgaaataa aaatcatgct ttatgtggac gatgtagaaa aaaatgcaac
       61 gttttggaga gcagttggct ttcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggcagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt agattttaat gcgaagctat ttgaagagtc
     4801 agacgaagag acgattgcag gaatcatcaa acatgaactt tgccattatc atcttcatct
     4861 agctggaaga gggtatcagc ataaagatat ggatttcaag tatcttttga aaaaaacagg
     4921 agggttgcgc tatgcaccag ccttgacgaa gaaacagata aagatggagt attatcgatg
     4981 ccaagattgt tctgccacga tctgccgcaa gagaagaatc gatgtacgca aatatcgttg
     5041 tggaagatgt catggagaaa tcaaatggat tgagacaaaa agagaagact ttaatgaagc
     5101 acaaaaaatc agatgaaagg atagaaggcc tttggaaaaa agtgagcaga ggaatctaaa
     5161 agactggaat cagctattaa attttttagc cgcacctgaa gagggaaatt ttgaggaact
     5221 gacggcacct acacttattt tagctggaaa ctgtcttcct atcttagctg ataaagcagc
     5281 acaaatgtat ttaaatggcc aagtagatca attgtttttg gtcggagggg tggggcatgc
     5341 gactagaatc ctttatgaga attttgaaaa gcaaggattt cattttgaag atggcatgag
     5401 tgaaagtgaa atctgtcgtc agtatctaaa agaagtctat gatttgcccg ataaggcttt
     5461 tctgatagaa tcgaagtcta caaattctgg agagaacgcc actttttcac tggagattct
     5521 tcattcctta ggagctgtac cagaaaaaat cttattgatg aatgatccga cactgcaacg
     5581 caggactcga gcaacttttg agaaagtatg gcaaaatgaa caaactattt tcgcgaatgc
     5641 tgtgccattt gtgccggaaa tccttcactt ttctgaagag atcatcttta cagcaaaaga
     5701 actgaatcat caatggccta aggaatattt ccatgcgcta gtattaggag aaatggaacg
     5761 tctccatgac gatgagaacg gctatggtcc gaaaggaaaa gattttattc ctcacattga
     5821 tatatcagag gaagtttggt cttcttacac cagaattaaa gagtcaataa aaacggattt
     5881 ttcccgtact tgaccatttt agcaagcgaa tcctcctttc caaataaatt tggttgaaat
     5941 tttcaatcgt ttataagata atgaggagcg tgttgaatgt aatagctaaa agaatggacg
     6001 ctagataaga gaagaggatt caaatggaaa atcaaaataa attgtatcat tttgttggta
     6061 tcaaaggttc aggaatgagc tccttggctc ttgttttaca tgaacaaggt ctaaatgtcc
     6121 aaggatcaga cattgaaaaa tatttcttta cacaaagaga tttagaaaaa gcaaatatca
     6181 cgattctgcc atttaacgca gataatgtaa aaccagggat gacgatcatt gcaggaaatg
     6241 catttcctga ttcacatgaa gaaatccagc gagcaaaaga attaggtttg gaagtgattc
     6301 gctatcacga ctttattggt cattttatcc aaaattatac gagtatcgct gtaacaggct
     6361 ctcacggaaa aacaagtacg actggactgc tctctcatgt attgagtggt gtccgtccaa
     6421 caagttatct aattggagat ggaacaggac atggtgatcc gcaagcggaa ttcttttcat
     6481 ttgaggcctg tgaatatcgc cgtcatttcc ttgcctattc accagactat gcaatcatga
     6541 ccaatatcga ttttgatcat ccggattatt atacaagtat cgacgatgta tttacagctt
     6601 tccaaacaat ggctggacaa gtgaaaaaag ctatttttgc gtatggtgac gatgcttatt
     6661 tacgcaaatt aaaagcaaat gtgccgattt attattatgg tgtcacagaa aacgatgata
     6721 tccaagcacg aaacatcgaa cgcacaactt ctggttctgc ttttgatgtc tatcatgggg
     6781 atgaatttgt tgggcacttc actgtaccag cattcggtaa acacaatatc ttaaatgctt
     6841 taggtgttat tgcagtagct tatttcgaaa aactggatct gaaagaagtt gcagaagaaa
     6901 tgctgacttt cccaggagta aaacgtcgat tcagtgaaaa gatcgtagca gacatgaccg
     6961 tagtcgatga ttatgcgcat caccctgcag agatcaaagc aacgattgat ggcgcacgcc
     7021 aaaaatatcc agataaagaa ataattgcag ttttccaacc ccatacgttt acgcgtacga
     7081 ttgcattgat ggatgaattt gcagaagcac ttgatttagc tgataaagtt tacttatgcg
     7141 atatttttgg ttcggctcgg gaagaacaag gaaacgttaa gattgaagac cttggagcga
     7201 aaatcaaaaa aggtggagaa gtcatcaaag aaaataatgt atctccattg ttagattatc
     7261 atgatgcagt agtaatcttc atgggtgctg gagatgttca aaaatttgaa caagcgtatg
     7321 aaaaactttt aagcagcacg acgaaaaatg tactgtaata caattactgc agtgtcctta
     7381 taaaaataga aagaggggga gtggcaaaaa tcttgccaag cccccttttt tgcaacttat
     7441 gataaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaatcaaat caaaaacatg
     7501 agaagctgtt tttcttggct gttcttatta cttgatgcag ggcagctttt tcacgacctc
     7561 agataaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaaa tgaaaaatat
     7621 gagaagctgt tttttcttgg ctgttcttat tatttgatgc aggacagctt tttcacgacc
     7681 tctgtaaact ataggaatct gttaaatcaa gggagcagaa cttgcctttt acgctacttt
     7741 tggtacaata atgtatgatt aaaaataaac tggagggttt ctatcttgaa cataggtaag
     7801 ccgagaaaac taggaaaaac aataaatgaa atcgaggaag gcgactcgtt atccttaaca
     7861 gaatctattg aagataacca gcttttgctg tatttgggat tgacgaatga tgcaaatcct
     7921 ttgtatatcc aacatgactt tgcacaaaaa acagaatatc aacagccaat cgttccatca
     7981 gtgatgctga tggggatcat cacaagtgca atttcaaagc atcttcctgg accaggatca
     8041 catgttgtca atttttctgt caattttatt gaaccggttt tccattatga aacactgact
     8101 tttcagtttg aggtcataaa agtagataag atgaaggatg tggtgacgat ttctgtagaa
     8161 gcggagaata cgaacgaaga tcgtgtgttg gatgctgtcg ttatggtcca accgccacaa
     8221 gttcctgaat tggaaatagc aatcgaaagt gaaggtgaat tgaatgaata atccaagtac
     8281 atcaatgtca ggtatcaatc gtttttatgc aaaagtttat ggatttttag gtatgggact
     8341 tgcccttagt gcagtcactt cttacttggc tctttgggta tttcctttgc aattagcaac
     8401 ttttatcaat aattttccac taggctttgt gggtctgtgg atcgttgaac tgattttagt
     8461 aatggttcta ggcgtaaaag cacaaaagaa tccgagctta gcaatcggtg gatttattgc
     8521 ctactctctt ttgaatggca taacattagc ggttactctt gcatactacg atattggaac
     8581 agtaacgcaa gctttcttga cagctacttt gatgttcatg gggatgtctg ttgtcggagt
     8641 aacaacaaaa agagatctta gcggggttgg aagagcagga caggcagctt taatcggagt
     8701 gatcattgca ctagtcttga acatcttcat tttgagaagt agcgtagttg agctgttcat
     8761 ctccctactg ttagtcgtca tctttgcagg gattacagct tatgataacc aaagcatccg
     8821 taatatctat gtccagacaa acggaacagc acatagtgga attgctgtat tcatggcatt
     8881 gaagctgtat ttggacttta tcaacttgtt cttggcgttt ctgagaatct ttggacggaa
     8941 caactaaaaa agaaaaaaat tcatcagttg gggctatacc gaa
//
LOCUS       DAFTHM010000102         8931 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFTHM010000102 DAFTHM010000000
VERSION     DAFTHM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.102"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(91..759)
                     /locus_tag="L7C88_002341"
     CDS             complement(91..759)
                     /locus_tag="L7C88_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBP9559142.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            893..1180
                     /locus_tag="L7C88_002342"
     CDS             893..1180
                     /locus_tag="L7C88_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559143.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1596..3134
                     /locus_tag="L7C88_002343"
     CDS             1596..3134
                     /locus_tag="L7C88_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBP9559144.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3131..4096
                     /locus_tag="L7C88_002344"
     CDS             3131..4096
                     /locus_tag="L7C88_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9559145.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4083..5405
                     /locus_tag="L7C88_002345"
     CDS             4083..5405
                     /locus_tag="L7C88_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBP9559146.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5468..5572
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5646..6389
                     /locus_tag="L7C88_002346"
     CDS             5646..6389
                     /locus_tag="L7C88_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9559147.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6404..7396
                     /locus_tag="L7C88_002347"
     CDS             6404..7396
                     /locus_tag="L7C88_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBP9559148.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7408..8145
                     /locus_tag="L7C88_002348"
     CDS             7408..8145
                     /locus_tag="L7C88_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9559149.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8135..8857
                     /locus_tag="L7C88_002349"
     CDS             8135..8857
                     /locus_tag="L7C88_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBP9559150.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
BASE COUNT         2979 a         1518 c         1868 g         2566 t
ORIGIN      
        1 ttttttataa agaagatttt actgaataat atcattttag tttacataat gatatttctg
       61 taaattaaat aaagtagtga aaaataagaa tcagtgctct aactgttcaa gaggatcaag
      121 tggttcaaat gtttctgtag tctgttttgc ttccaattgg ggcaaaacag atccaatttc
      181 cagatacttc actttattca atgtataaga tagaatagaa cagctaagta atgtatacag
      241 aaaatgtgtg agatccaaat aaagcaagga gacaactaaa ataccaaaag taatcaagaa
      301 aagacttttg ccaatcttaa tatgaaaata tttttcaatg gcttgataaa tgatatctgt
      361 tccgcctgtg cttccgccga atcgaaagac gagaccgcaa ccaatgccag aaagaatacc
      421 tgtcatcaaa ctattgatca gtagactatc tacagcaaaa tgtatatgaa ggctctccca
      481 taaatgtaaa aagaaaacta gcgcaaatgt tccgacgatc gtccggagaa aagcgtgttt
      541 tccaaaaaga aacaatgaga taagcaataa aggtaaatta aaaagcagtg aagtgacaga
      601 aggagcgaat ccaaaaagat tatgcaaaag caaagcaata ccagtaaccc caccatctgc
      661 cagcttagat ggaatattga ttcctgtcac agctaatccg tagattcctg cgcctaaaat
      721 gattccgcac aattctgtaa ataaatttaa ttttttcatt tctagcctct tttcttttga
      781 aaattttcag caacttcttt attatactga cttatactct tacttcaaga ggaaaatgaa
      841 aaaaaattat ttttggctgt ttctttttat ttatcaaata aggagtggaa aaatgcgagc
      901 agcagactta ttgacaattc ttacaaaatc acccaaaaaa acagagtatc aaggagtttt
      961 tttggctcaa gaacaaaaac tggtgcctgt gacaatggtc cagataaata aagcaaatca
     1021 atttatcttt ttatttgaac acggcaaagc accacttgct atgaaagaca tctttctttt
     1081 tttgatgaag aaccgtgaga aagctgttta ttatcagtca aaagaagaac tcattcctct
     1141 ttatggagtg aaagagatag aaaataaagt ggtgatataa gtaaaaataa gaaaacaaga
     1201 cgtttatgat gtcaaaacaa ccatttttta catttttggc aaaaaagtgt catgatacag
     1261 tataatattc gttgaacagg ccaataaagg tgttctcccc cacgagattt ctactttatt
     1321 ggctgtttct ttttattaaa ataaaagttg tgtgtgtaaa aaagatatag ctgattccaa
     1381 gtgacaattt cgtatagatt tttatggtat tcgtagtgaa aaaacgagaa ccaaaaagtt
     1441 gatccgactt tgttgcttgg attctttttt tgtcagcata tttagaggta tttttttctt
     1501 ttttttgttc gtgctgtaag gttaaggcaa gacaagttag ttgggaaaaa ggaaagaaat
     1561 gtttatactt aaagaataac agaaaggaag gtcgcatgaa taattttata caaacattaa
     1621 gtgaaagaaa aggcgagttg ctggaagctg catttcaaca tctgtccatt tctctcattt
     1681 ctttgctgat tgcagcactg attgctattc ctttagcgat ttgggcagcc aatcataaaa
     1741 aaatggcaga agtcttattg cagatcacgg gtgtgctcca aacgattcct tcacttgcct
     1801 tattaggttt acttatccca tttgtaggga tcggaactgt tccagcattg attgcacttg
     1861 ttatttacgc tttgcttccg attttccaaa acacgtatat tggtctagct gaaattgacc
     1921 cgtctattga agaagcagcg gtagcatttg gtatgtccag aatgagacgc ttgctgaaag
     1981 tagagcttcc catcgcatta cctgtcatta tctcaggtat ccgaactgcc ttagttttaa
     2041 tcatcggtac ggctactttg gcagcattga tcggagcagg tggattaggg acatttattt
     2101 tgttaggtat tgaccgaaat acacctgttt tgacattgat tggtgcgatc agttctgcct
     2161 tgcttgcaat tatattcagc ggactgattc gctggttgca gcataagaaa cctcgatatt
     2221 ccatcattac tttagcagca gtggtgtgtt tatttggcgg cgtttcttta tatcagtctg
     2281 ccttgtttaa aaatgaaacc atcacgattg ctggaaaatt aggagcggaa cctgaaatcc
     2341 tgatccaaat gtataaagaa ttgattgaag acaacacaaa aacagaagtt gaattaaaac
     2401 cgaattttgg caagacgagt tttttgttca atgcactgga tcaaggtcaa atcgatatct
     2461 atcctgagtt cacaggtact gtcctagaaa gcttggtgaa ggtacctgaa gcaatgaaaa
     2521 gtgctgattt gacaaaagaa aaaacatatg acgaagcaga agaattattg aataagcaat
     2581 tcgatatgac attattaaaa ccaatggctt accaaaatac gtatgccttg gcagtcaaga
     2641 gatcttttgc gaacgaacat caacttaaaa agatttccga tttggcagct atctctgatc
     2701 agatcaaagc gggattcaca ctggaattta ttgatcgttc agatggatat aaaggaatcc
     2761 aagaagcata tggcttgaat ttttcaagtg tacaaagcat ggagccaagt ttgcgttacc
     2821 aagcaatcaa taatggagat gtcaatattg tggatgccta ttccacagat agccagctca
     2881 aggagtacga tctagtgact ctagaagatg atcgagggtt attcccagct tatcaaggcg
     2941 caccgctgat gaaaaaagat tttgctaaag aacatcctga aatcgttaaa gcactgaata
     3001 aattaagcgg aaaaataacg gaggatcaaa tgattgatat gaattaccaa gtcaatgtcg
     3061 aaaagaaaaa gccgacagaa gtagcacgaa tcttcctgaa aaatgaagga ttagtaaagg
     3121 aggaagatca gtgactaaat taatcgagtt caaacatgtg caaaaaaagt atgatggaaa
     3181 gtatgtcatc gatgacctaa atctggcaat caaaaaagga gaaatctttg ttttggttgg
     3241 tccttccggt agtggaaaaa caactacttt gaaaatgatc aatggattat ctaaaccatc
     3301 agcaggagac atctacttca aaggaaaatc gttaaatgaa tataatctgc agaaaatgcg
     3361 gtggaatatg ggatatgtgc tgcagcaaat cgctttgttc ccgaccatga cagtcaagca
     3421 aaatattgaa gtcatccctg aaatgttagg ttgggaaaag cagaaaagag cagaccgtgt
     3481 agatgaactt cttcaaaaag ttggcttatc tcctgatatt tatcgagatc gtatgcctag
     3541 agagttgtct ggaggagaac agcaacggat cgggatcatc cgagctattg ctgcaagccc
     3601 agatgtgatt ttgatggacg agccatttag cgcattagat ccgatttcaa gaaactcatt
     3661 acaagaattg gttttgtcct tacacgaaga attgggcacg accatcgttt tcgttacgca
     3721 caatatggaa gaagcaatca agctaggtga tcgtattgca tttatgaagg atggagaaat
     3781 tatccaatgt gacacaccag agcagttatt gatgaatcct aaaaacgact acgttcggca
     3841 tttctttgat gaaccgaaac agacgaaaga gtggcgagta gaagatttag tcgtcaatgg
     3901 atatttctta aatgaaatac cagaaaatgc tcgtcaacaa gtttgctttg atacgcctat
     3961 gaaagaagta tattcgcttc tttcggtgta tccaagcatt gtgatagtag aaaagcaaag
     4021 aagtattggg tcgctgacaa gtaaagaaat ctttgctttt ttaagtcgag aggaggaagg
     4081 aaatgaaaac atatgatgca atcatcatcg gttcaggtgt gagcggctta agtgctgctt
     4141 atggattgaa agaagcaggt aaaacagtac tagtggtcga agaagatcta tggggcggga
     4201 cttgtcctaa ccgtggatgt gatcctaaaa aagtcttgtt aagtgcagta gaggcacgta
     4261 atcgggtaaa acaattgagt ggaaaaggtt ttaacgagat cccaactgcc aactgggaag
     4321 aacttcaaaa attcaaacga acatttacgg atccagtccc agaaagccga aaaaaacaat
     4381 tagcagaagc tgaaatcgat catctttcag gaaccgctcg ttttttggat gattcatcta
     4441 ttgaagtcaa cgaagaagtc ttccatgcgg attacttagt tttggcaacc gggcaaagac
     4501 ctacgatctt accagtggag ggaaaggaat acttgaaaac tagtgcagac tttttatcat
     4561 tgcctgtact gcctaaagaa atcattttta tcggtggtgg ttatattgct tttgagctag
     4621 ctacgattgc caatgctgca gggagcaaag taaccattgt ccatcataat caacggccat
     4681 taaaagaatt tgaggcgtct ttggtagagg aagccgtcca tcaaatggaa gcatctggca
     4741 ttcagtttgc ttttggtgtt gaaacccaaa agatcatttc agaaggtact cgctatcgtt
     4801 tagtcggaaa agagacggaa ttagtagcag atatgatttt ttgtgcgact gggagacagc
     4861 cgaatacaga atctttagca cttgagcaag cgaatatcgt ctttgataaa cacggaattg
     4921 cagtcaatga ttatctgcaa acgagcaatc caaaaatttt tgcgtgtgga gatattgttt
     4981 caaggaaaac cccaaaattg acaccagtcg ccacttttga aggaaattat gtagctaagc
     5041 ggataacgga tgcaacaagc gaacctatca aatatccgat tatacctacg atcgtctacg
     5101 ccagtcctaa acttgctgaa gtaggagtta caaaaagtca cgcctcttcg tcagatcaag
     5161 tggtagagat ggatcttacc agttggttca cctatcatcg tgtcaatgaa ccagttgcta
     5221 aggctgaatt gacctttgac cagcaaaatt atttgattgg tgctgcagtg attagcgagc
     5281 aagcagacga attgatcgat gatttgacac tcgtcatcaa tcaaaaattg actaaaaaag
     5341 agttggatag ctatatcatg gggtatccga cattggcaag tgatctctcc tatttattga
     5401 aataatcagc atgataacta aagcgcttgt tgctttttcc ttcttgtgct acactttaaa
     5461 aaatgaatac ctgtttctgg ggatgtcgta gacgacatga gagtaagttg tgaacttaga
     5521 cccattgaac ctgtcagtta atactggtga agggagaaac atagcagacg cttgaagcgg
     5581 gttactatgt cgtgcccatt tcaagcgttt tttgttattc atattagaag aaaggaggta
     5641 acaaaatgaa gaaaaatctt tatccagcag tcagtatggc attcatttta attatttggc
     5701 agattgttgt catagtttgg aaaatacctg cctttatttt acccggacct gctgctgtat
     5761 tttctgcatt agcggcagat gcacaagtat tactttccca ttctgtcacg acattaaatg
     5821 aagcagtgct tggtttggta atagctagcg ttctttcttt tattactgcc ttggcaatgg
     5881 attattggaa gtttttagaa atgtcttttt atccgttact agtgatttca caaatgttgc
     5941 caatcatggt gttagggcca ttacttaccc tatggtttgg tttcggtatg cttccaaaag
     6001 tgatccttgt tgtcttgata agctattttc cgatcgtagt ttctttttcg gatacattga
     6061 ggaaagtatc aaaagagcaa atcatctttt tgaaaacgat gggggcagat acagggaaga
     6121 tttatcgaat atataaaata ccagcgggtt tatccggctt cttttccggt ttaaaagtgg
     6181 ctgctactta ttgtgtcagc ggagcagtcg ttggagaatg gctaagcgct caagcaggct
     6241 tagggtatta catgatacgc gtaaaaaaca gctaccagat cgataaagtt tttgctgcga
     6301 tcatttgtgt cattctattg agtttattgc tgaatggcgc ttgttcatta ttgaaaaaag
     6361 ggtattatcg tatgctttat attttttaag agaaggggat caaatgaaaa aattatggct
     6421 tttattaccg ctactgttgc ttttatccgc ttgtggcact gcaaaagaaa caagtagcaa
     6481 acaagaaata aaggatttga aaaaagtgac acttgttttg gattatgtac cgaatactaa
     6541 tcatactggc atctacctag caaaagaaaa aggctattat aaagaggctg gtttaaatgt
     6601 ccaaatcatc gaaccaggag ataattcgac aagtattggt ctagtaggtg cggacaaagc
     6661 acaatttggt gtaagttatc aagaagatgt cacttatgct cacgcagatg gacagaatat
     6721 accagtcaaa gcaattgcta cagtgatcaa acataatact tctggattcg ccaccctatc
     6781 agacagtaac atccattcac caaaagattt tgaaggaaaa acatatgcag gttggcaaag
     6841 tccaagtgaa gaagctgtct taaaagctgt gatggaaaaa gacggcgggg acttttcaaa
     6901 actgacaatg gtaggaagca atggagaagg gccagaaagc ttaggaaaat cctcagatat
     6961 ccaatggtac tttgaaggtt gggatatgat caaagcaaaa gaagcgggta ttgaactaaa
     7021 ctatatccca ttgaaagaat tagatgaacg gttagattac tatactccgg taattattac
     7081 gaatgatcaa ctgatcaaaa gtgatccaga attggtacag tcttttatgg atgccacgaa
     7141 aaaaggctat caggaagcta ttaaggatcc aaatgacagt gctaaactgt tgcaaaaata
     7201 tgcaaaagaa aatgatcgga cgtttttaga agaatcacaa gcattcttgt caaaaaatta
     7261 tacggatgat cctgagaatt ggggattgat ggaagaaaaa gtttggcgca attatacagc
     7321 ttttatgcag gaaaacggat tgatcaagca agatgtacct tcgcaagaac tattcactaa
     7381 tcagtttata aaataggagt gatagatatg tcaatccaaa tcagccactt gaatgtagtc
     7441 attgaaaacc tgaaaatatt agaagacatc catttcacta tccctaaaga tacctttaca
     7501 tcgattgtcg cgccaagcgg agccggtaag tcaacattgc tgaaaacttt aacaggagtc
     7561 cagcctatga cttctggaac gatcaaagta gacgatcaaa aagtaactgg tctccataca
     7621 gcatttagtt atatgccgca agaagatatg ttacttcctt ggctgagcgt ctatcaaaac
     7681 gttacgttat atcaaaaaat caatcatcta acaatcaatg aagaacaagt aagggattat
     7741 ctggatatct ttgggttaaa cggctatgaa cattttttgc cggaacaatt atctggcggg
     7801 atgaagcagc gaacggcctt gttacgaaca atcatgaatc cttcttctta cttgcttctt
     7861 gatgaaccat ttggagcgtt agatgctatg accagagggc agatgcaaga ctggatgttg
     7921 aagctgccta aaaaagcaaa gcggactact ttacttgtga cgcatgatat cgaagaagca
     7981 atttatttat cagacaggat tcttgtgctt tccgcccgtc cggcacatgt gattgctgag
     8041 attcaagtgc ctgaaaaacg acggtcacgt gaatggctac tgcagcaatc agagttgaag
     8101 caaacgattt atcagttatt ggcaggtgaa ttagatgtta agtgatgctc attgtcattt
     8161 agatgggagt cagagtttag cactccttca gcaggaacac acgattttga cgatcatcaa
     8221 ttgtgattcg ccagaagaat ggaaggaaaa cagacagctt gcagcaagta agactcaagc
     8281 cttaagttac ggtatccatc cttggaaagc agatagctat acgtttgaac aagttgagcc
     8341 ttttttgaaa aaagcaagga tcatcggtga aatagggtta gataatattt ggacgaatgt
     8401 accgatgact acacaaaaaa aagtatttga gcgacagctt gcttttgcag ccataaatga
     8461 gaaacctgtt gtactgcaca caaaaggatg cgaaaaagag atcttaaatt atatccaagc
     8521 ttaccctaat cactatttga tccattggta ttcttctttg gactatcaac aagactatat
     8581 tgatttaggc tgttatttca gcattggtct tgatttgaaa aagaatccag cagtctggca
     8641 actagctaaa gcagtcccaa tcgaccactt acttattgaa acggatggac tacatgcagc
     8701 agagtgggct ttagggggga ttttttcaga aaaagattat gtctcactgc ttgaagaaca
     8761 gttaaagaca atcgctgaga tcaaagagct atcagttgaa gaagttaaaa aaaatactta
     8821 tcaaaacttg gaacgtttca ttagattagg taaataaaaa agagatgtga cacaactagt
     8881 gtcgcacctc tttttggctt tctttgtata aaagtaaact gtttgattaa t
//
LOCUS       DAFTHM010000103         8904 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFTHM010000103 DAFTHM010000000
VERSION     DAFTHM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.103"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(305..661)
                     /locus_tag="L7C88_002350"
     CDS             complement(305..661)
                     /locus_tag="L7C88_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBP9559151.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(675..1085)
                     /gene="spx"
                     /locus_tag="L7C88_002351"
     CDS             complement(675..1085)
                     /gene="spx"
                     /locus_tag="L7C88_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBP9559152.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            complement(1432..3618)
                     /locus_tag="L7C88_002352"
     CDS             complement(1432..3618)
                     /locus_tag="L7C88_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBP9559153.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            3836..4519
                     /locus_tag="L7C88_002353"
     CDS             3836..4519
                     /locus_tag="L7C88_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBP9559154.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(4600..5319)
                     /locus_tag="L7C88_002354"
     CDS             complement(4600..5319)
                     /locus_tag="L7C88_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBP9559155.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTNK"
     gene            complement(5631..5837)
                     /locus_tag="L7C88_002355"
     CDS             complement(5631..5837)
                     /locus_tag="L7C88_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559156.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            6082..6684
                     /locus_tag="L7C88_002356"
     CDS             6082..6684
                     /locus_tag="L7C88_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBP9559157.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            6825..8105
                     /locus_tag="L7C88_002357"
     CDS             6825..8105
                     /locus_tag="L7C88_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBP9559158.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIDDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            8118..8846
                     /locus_tag="L7C88_002358"
     CDS             8118..8846
                     /locus_tag="L7C88_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9559159.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
BASE COUNT         2587 a         1667 c         1463 g         3187 t
ORIGIN      
        1 actcagttat cttatcatgt catttctaac atgtcaacaa ctattttata tgttttttaa
       61 aatactattt tattgctttg ctacttaaaa caacagaaat gaatatatca tgtaaattta
      121 cacatgtcaa tatattttta actctatatc cccacctaga tttgaatttt gaccacataa
      181 attgagcatg tctctatagt agaaaaataa agtcaaaaaa agaacacata acacgcttga
      241 tgctaagtgt tcgactgtta caactgtatg aaatgctcag tgacttgatt aaaacagtta
      301 aagtctattt atttaagata agctgttcca tcaactgctc attgtatcca ataaatagaa
      361 cttcatcgat aataatcaaa ggacgtctga ggagattggt atgttgtgtg cataaaaaaa
      421 tcagttgttt ttttcctaca caggaaaggt caatcgcaat gttgtgaaaa gcctcagacc
      481 aagtcgcaaa tagctgttct gcttgcactt cttcaaaact gcataattct tctgcttctt
      541 ctgtacttag atcgcgttct tctaagtcaa caaattgata aggcaattga tggtgttcta
      601 accattgttt cgccttcaga cttgttacac agtgcgctga tccatagact ttcacttcca
      661 cgaaggctcc ctccctatga atttaagatg ttattgtttt gtaaatagat cagatttctg
      721 gcaacacatc gaatttcacg agggacaaat gaccggatct catcttcatt aaatccgatt
      781 agtattcttt tttcatcaat caaaataggt cgtctcaata atgaaggata ttctttgaat
      841 aagacgatca tttgctttaa agttaattcg ttaaaatcta tgcccagctt ttcgtaaatt
      901 ttcgaccgag tggaaataat atcttgaact cctccttcag tcgctgccaa gatctttttg
      961 atctcacttt ctgttaacgg ttcggcaaaa atattcttct cttcaaattc aagttgattc
     1021 gcttgcaacc atgctcttgc ttttctacag gaagtacagc taggcgaagt atatactttt
     1081 atcattttct cactcatttt taattataat ccaattctac agtaatttct tttaaaatac
     1141 caattattag ctaataatat ataaaaaaaa atcaaaataa ctgattattt acgtttgaat
     1201 aatgagaatt tttctatata ttctctattt tgataatagt attctcattt tcaaaataaa
     1261 taagggaggt gtgacaaaat tcttgtcaca cctccctttt ccgaataaac tgtgttccag
     1321 aaatagcttc ttcgaaaata agctgaaatt tcacaaaaat ttgagaagca attttcgtac
     1381 attccttctt ctttcttgaa actgaccact tctgtcacac cctctcttct atcactttcc
     1441 ttttttcaca cgactcccgg tttctttgat aaatctcgat actttcaatt ttcttgaatt
     1501 tttcatttga ggtacacata gatacagacg atttcttgct ctagtcatcg caacataaaa
     1561 tagtcttcgt tcttcttcta tcgtcgtcac tggttctgct tttatttcat taaagtcgat
     1621 tactttcttt tctgtcgctc cgttataagg caaacttcct tcgttacaac caatcaaaaa
     1681 gacatttcgg taactaagac ctttactttt gtgaatgctc tggatacata gtgcatcaag
     1741 ttttccttgt ctgtaagcaa tcaagcgggt ttttaattct ttagctgtcg cttgggtttc
     1801 ttgcgataag gcttggagtc ttctgaaagt agcatgctgc tttacttctt ctcgtatcca
     1861 ttcttgatca ctctggtcga tttccttagc tatacgtggc agatgaagat agctttgaac
     1921 aagcgaatag atttcttgat gctggtctgt tttacgcaac gcttcctcaa actctcggat
     1981 ttctgcagat ttcgatttta aattggggct tatcgacaaa atataatctg caacggctat
     2041 attttgatat ttaggagaaa agtattgatc gcattcactt tttttcaggt agcagtctgc
     2101 catcagctgc cggagcaatt gctggtaggc ctgatttttc ttttgcagat tcagtgctgt
     2161 ttgccaatga acaatttttt gatagaaatg ttggaaagac ttgataccaa agataccttc
     2221 atatggacta tctgcttcca gtacaaaagg aatattcgtt ttcagcagag attggacaag
     2281 ctgctgcgtt tgtgaagctg atcggtataa tatgattgat tccttatatt tcccattttt
     2341 ttgaataaat gtctgaattt gtttgattag ccactgactt tctgctttag tatcagaaaa
     2401 caaataggct tccataacac ctgcttcttt ttgtgctgga atcatcgcct ttggtatccg
     2461 atcattttta ttatagctga tcaatctatt tgctccttgg acaatagctg cccgagaacg
     2521 ataattagtc aataagaaaa gagttttggt aggatattct ttttcaaagt tcttgatgta
     2581 tgctggctct gatcctctga atccatagat actctgatca tcatctccaa caacaatcaa
     2641 cttgatcctg ttttcctttg tcatccgttt cacgatttcc cattgaagtg gattagtatc
     2701 ttgaaattca tcaatgaata gataatcata tttttggccg atataatgct ggatctcctc
     2761 attctccaaa gcgcttttca gattttggag tacatcattg aactctagca attgctggct
     2821 tcttttttgt tcttggagtt ccgtgagcaa tccatacagt cgttctgata tcggctgtcg
     2881 tgcattctta tcaatggaat catatttttc tttaactaac tgaaccattt cttctactga
     2941 aaggttcata ttctgccaat agtctaaccg agaagcaatc gttttttctc catattgatc
     3001 aaatatataa agattatatt tacgtatcag ctgttgcaaa acagcattca ctttttgtgc
     3061 agtatccttt gaaaagtctc cttgtattcc ttgcattgct acttcaggaa attttcgaca
     3121 aatttcattg tatatcctaa aaaagatact atggaatgtt ccgatatgga cagcggtttt
     3181 tctctggctg aaattatcta ctcgtttttt tagttcattt gcagcgttcc ttgtaaaagt
     3241 gatcattagt atgcgttctt cgtctacttg tttttgcgtc atcagataaa cagcttttgc
     3301 acagattgtt tgcgttttgc cgctcccagc tcctgctatg attcgaagat gtttcttcat
     3361 atcatatgtg atagctgctt tttgttcttg attgaagcga ttataggaac gtttctccat
     3421 cattttaaag aaagagctgt ttccttcact ttcttttact tgtacttctt cctcaataag
     3481 tccgggtgct tcgccataag ccgcttcata ggtagcaatg atttcttctt gtagccgaaa
     3541 gacttgttga agctttttat acttgttctc ccagcgtttc aattcttttt gtaatcggag
     3601 aatttctttt tcattcaact gattgatttc cttcccatct ttcttctttg aatttgttta
     3661 tttcaagttg gttatttaaa gtttcgttgt ctattttttc tttatactaa cagacctttc
     3721 taaaaatgaa aatgggaagc gatatgattt tagttttctg aaaatttttc ctttttttca
     3781 atcgtttatg ctaagataag gaagacaaaa atattcataa aaggtgatga aaaaaatgca
     3841 gacttccttt cacgaggggc gtacaatagg acttttgctg acatttatcg gaggagccat
     3901 ggacagttat acttatatcc aatatggtgc ttttgcctct gctcaaactg gcaatatcat
     3961 tctatcgatc atccaagcat ttgacggaga atggctaagt gttggtaaaa aagtattgtc
     4021 tacccttttc tttttcttag ggattcttct aacaaagtat ctaattgatt attttagaaa
     4081 aaaagaaaaa catttctggc gcttgtttgt tctatattat gaagcagtga tttttttctt
     4141 tgttagtttg acacccgtcc atgagcatcc cgcattagta acgattttga ttgcttttac
     4201 tgcatcgatc cagtgggtag cttttgataa aatcaacggg cgtgcctaca ctaatttatt
     4261 tacaactgga aatttaaaag gggtagcaac gaacttatat gattattgta tttctaaaga
     4321 aaaagcagat tttgatcgat ttttccacta tctaagtgtc gttcttgcct ttatcgcagg
     4381 agctattgtc cttgttttct gtcatcatct gtttggcgcc cattcgattt tgatcgtttc
     4441 cattttattt ttgatcatgg ccctcactca gacatttcat ttatggcaat tttatcatac
     4501 gaatcggttc actatttgat ctcaatgaat caaaaaaact aagcaagatg ctgctcacag
     4561 agaaatatct gcgagtgagc aatttgctta gtttttatat tatttatttg taaagattcc
     4621 ctttgctttc gggttatttg tagtgtagcg gatcgactgg gcatctgcct cttctgtcat
     4681 tttctttgcc cgcatcttga tttcttgtac gatttgttct ccacatgccg gatcggctac
     4741 gaaatcatat ttgtccccat cgatcactat tttgggacat atatcaaact gttcatacca
     4801 ctcttcgtat cgtcgattga gttctttata gtaggaatag agttcaggat cttgttctag
     4861 ctgttcatat tcccggcctc tttttttgat tctcgctaac atagtttcaa aggatacacg
     4921 aatataaacc agtagatctg gtttcttttg tggcgaaatt tcttctaact ccttcagcat
     4981 cgtttctaaa agaccttcat actgctttac ttctacttca gaaacacgcc ctaaatctgc
     5041 attcaaatga aacagcatac tatcttcgta gatggagcgg tctagtacgt tgtcatcatg
     5101 gctgaaagca tctttgattg ccaaaaagcg tttgttcaaa aagaaaatct gtaataaaaa
     5161 agtatacttt tctggattag aataaaatag cggcaatact tcattatctt ccacgttctc
     5221 ataaaaaggt tttgtttcta aatcttgggc aagcatttca gttagtgtgc ttttccctgc
     5281 accgatcgtt cctgcaacaa tgatcacaat tatcggcatc cttcctgtaa taaaatctgt
     5341 tcttcatttt actacttcat ttatagaaat aaaagccttg actttatctg ctccttaaaa
     5401 gctacttctc taaaagtagc caaaagtaac tcctattcat gaaaataaag gctgtgacaa
     5461 aagtcttgtc gcagcccttt tttcaaataa acagtattct cctgccaaca cctcggtcac
     5521 aaggcaatat tcataaaaca tgaaaagctg ttttttaaca ttattccttg taactcagag
     5581 ctaaacggga gactcacaac ctctttatgc tctcaacatt ttatctgttt ttattcttct
     5641 attgtacttg atttgcgtac aactaactgc cagtgcagat tatgagcggt atcattgtct
     5701 tctactgcgc atttcatgac acgtatcatc acactatttt catagatttt ttctattttt
     5761 ccttttattg gtgattcaaa taaatcagat ttaaatgcat atgtttcgcc gacttcaaac
     5821 aattgttcat tttccataag aatccctcca tcacctttta taaggtcagt aattttttaa
     5881 cataaatcac tcgaaaaagc acaaacttgt cataaaaagt acttttcgta tcaaaactgt
     5941 cacttttttt ggtaaggttc ttggaaaacg aagatttttt taggagatca tgacggtttt
     6001 gatgtcaaaa ccacttttta tgaaacaaaa gacgtttttt atttttttta gcataaaatt
     6061 tgtggtggag gtacgtatga gatgaaagat aaagttgtga acaaattatt agaagcctta
     6121 ttcagcggag acaaatcgga agaagatatg gtgtatgtcc aagtaaaatt tgccttagaa
     6181 gttttattga ataatcttgg aaaactagcg gtcgttctag tcttttctct ggtgacaggc
     6241 tcatgggcgg aaacaggaat cacctttctt tcttatatct gcatccgcag atatgcttat
     6301 ggattgcatt ccgactctga attcgtttgt ctgctgtgga cactacttta tttatggggc
     6361 gttcccttgg tgatgaaaca tctgcaattg actatctcct tcccaatgat ggtctttttg
     6421 ttaatcagct gctttttgtt actgcttcgc tatggatcaa gaggtacagc aatcaatccc
     6481 attgaacccg agaaacgtcc cccattatta aagaaggcga tcagcatgtt tctaattttt
     6541 tctctcatta ctttattttt ctcagcttct tacttttcta cctatttgct acttgggatt
     6601 gttttagaaa tagctacgtt gcttcctatt acaaactact tgatgaattt tggaggaatc
     6661 tttcatgaaa aaaacaatca ttaaacaatt aactaactta tctgactttt ttgtatctgg
     6721 ctgctgcttt ggtatgagtt ctgaattcaa aatccctgaa aaattaaaaa aataatacgc
     6781 taattgtgct ataatttggt aaaaatcaat gggagctgta ctttatgttt ttatggtcca
     6841 tagcgttgca atatttgatt tacacaattt gtatcttatt gattgaccat cacatccgat
     6901 acaaatatct gtttgcggga gtcattctga tttcttgtat tttgattgga tgggtctatt
     6961 cgattttagg gatttttact gctctaattg ctataggaat gctgatgctt acttttttct
     7021 tcttttcgac ttcgcgtcaa caattggttt acgcgcttcc ttttgggtta ttgacgtcgc
     7081 ttttaggaga tcacttaaca agcatcgacg atttttttgt tttgaaatct tcggttattg
     7141 aaccaggaga ttcattgcag tattttcaca ttgtcttatc cgctttttta tctgctttat
     7201 tagctttttg tttaaaaaaa tcgttagaga cttggtttca cactgtggac cgccgtatga
     7261 tcggtacgat cgggacattg atattattta catactatat cattattttt tatacccgtt
     7321 tttctggtga aacacctgat gtcttagctt tgaatacgag ttttttcatt ctatatctgt
     7381 gtgttggcct gatcatcttg gtttattatt ggaaaatctc taataagaaa ttagctgatc
     7441 agttattaga gcaacaagtc aggatgcaac aggattatat caaagatcta gaaaaaaact
     7501 atcaagactt gagagaattc aaacatgatt accaaaatct gcttttttct cttcacagct
     7561 atatttcaga aggcgactta gaaggattac ggtcttatta tgatcaaacg atattaccta
     7621 cacgccagat gatgaacctt tttccggcca atctaagtat gttggataat atgaaagttc
     7681 ctgagatccg tagtttactg tcattaaaac tcatgatggc acaggaaaaa gggttgatcg
     7741 tccagcttca ttttcctgag ccaatcgaac tggatacgaa acatacggta aaccttgtac
     7801 gtatgcttgg tattatcttg gacaatgcga ttgaaggagc tagtgctgca aagaagaaaa
     7861 aaatcgaatt gaccatactc aagaagaatc attccgtgat gattcgtgtg atcaatacaa
     7921 caacaaatac attaccgtta aaccagttga aacaaaaagg gttctcaaca aaaacaaatc
     7981 caaaaaacga aggccttggc ttgtttatct tggatgaatt gacaaagacc aatccttatc
     8041 ttttccttga aacatcaatt gaaaaccagc gtttttctca aacgatttat atacaaataa
     8101 aataaaggag taatgatatg attcccattt atatttgtga agacgatcca aaacaattag
     8161 aagttttatc aacggtgatc aaaaatagaa tcatgattga aaacttagac agttatgtcc
     8221 atatttctac ctctgatccg gaagaacttc tcaatgcagc caagatcaga acttcttctt
     8281 ttggtattta ctttttagat atcgaactag aagacagtga aatggatggt gtagcgatcg
     8341 gtaaattgat ccgtgaatta gatcctttag gaaaaataat ctatgtgact tcccatacgg
     8401 aaatgtcgat gaaaatctta aaaagcaaca tcgaaccgac tgattatatc gtcaaagaag
     8461 atctttatga tttaaaagaa aatgtcgagc atatcctgag caaaattttc gaagattttc
     8521 aaatgtccca aatccaaaaa gatatcttca aaatagagtt taatgatgag atcaaatttt
     8581 taccgatcaa agacatccaa tatttttcta cttcgctagg agcgccacat aaactggaag
     8641 tccatttgac tcatgcccaa ttacaattct atgagaagat caaagaaatc gagaaaatgc
     8701 atcggaattt tatccgttgt cataaatcct atgttatcaa tacacaaaat gtgcggtcga
     8761 ttaataaaaa aaccagagaa gtcacgttgg caaacggcga gaccatccca gcctctatcc
     8821 gtggattaaa gaaattgatt tcataaaaag aaccgaatag tttggaccga ctaaatgacc
     8881 agccgatcca aacccttcgg ttct
//
LOCUS       DAFTHM010000104         8865 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFTHM010000104 DAFTHM010000000
VERSION     DAFTHM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.104"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(443..940)
                     /locus_tag="L7C88_002359"
     CDS             complement(443..940)
                     /locus_tag="L7C88_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBP9559160.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(980..1789)
                     /locus_tag="L7C88_002360"
     CDS             complement(980..1789)
                     /locus_tag="L7C88_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBP9559161.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            2123..2980
                     /locus_tag="L7C88_002361"
     CDS             2123..2980
                     /locus_tag="L7C88_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBP9559162.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            2973..3875
                     /locus_tag="L7C88_002362"
     CDS             2973..3875
                     /locus_tag="L7C88_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBP9559163.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            3908..4258
                     /locus_tag="L7C88_002363"
     CDS             3908..4258
                     /locus_tag="L7C88_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBP9559164.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            4307..5229
                     /locus_tag="L7C88_002364"
                     /pseudo
     CDS             4307..5229
                     /locus_tag="L7C88_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
     gene            5307..6200
                     /locus_tag="L7C88_002365"
     CDS             5307..6200
                     /locus_tag="L7C88_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBP9559165.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            6238..6801
                     /gene="amaP"
                     /locus_tag="L7C88_002366"
     CDS             6238..6801
                     /gene="amaP"
                     /locus_tag="L7C88_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBP9559166.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            6815..7003
                     /locus_tag="L7C88_002367"
     CDS             6815..7003
                     /locus_tag="L7C88_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBP9559167.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            7016..7918
                     /locus_tag="L7C88_002368"
     CDS             7016..7918
                     /locus_tag="L7C88_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBP9559168.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            7950..8192
                     /locus_tag="L7C88_002369"
     CDS             7950..8192
                     /locus_tag="L7C88_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBP9559169.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(8448..8819)
                     /locus_tag="L7C88_002370"
     CDS             complement(8448..8819)
                     /locus_tag="L7C88_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559170.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3083 a         1542 c         1729 g         2511 t
ORIGIN      
        1 tggttagagc agacggctca taaccgtccg gtcgtaggtt cgagtcctac aaggtacata
       61 agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa cagccaagta aaaacagctt
      121 cttatgtttt tacttggctg ttcttattac tgcagatgca agcttttgaa taccgtttaa
      181 ggaagaggtt gtgaaatcag cgttttgacc tgagtattag cttaacaaac ggaaaaatag
      241 ttcctcatat tttgccgttt gttaagctaa taccgagggt cagctgattg aacaccattt
      301 aagaaagagg tcgtgagcct gccgtttcac tctgtgtcat aaaaaagcca atctactttg
      361 atagaaaaag cacgtaggac taaaacagtt ctgcgtgctt tttttattgt gtgttaaata
      421 tcgtaaatga agatagatat ttttatgatt cgacgataga gacgttgaaa tctttcaaca
      481 gctctaaagc ggattctccg tgttttctac tggagactaa cattggatca acaaaaaagt
      541 ctgcttcagg aaaagcactc tgcaggccta tcagattaga gagtacacac aagtttgttt
      601 caatcccgac tacttcgatc tctttttgtt cttctttgct ttcaaataaa gtttcctgga
      661 tttcagctaa agtttcaggt ggaatcgtaa agtaatactt tttaatcact cgttcatttt
      721 cttgtggaga aagaagaggg atcaattgca aatcttctcg ttcttcttct ttgtccttca
      781 gttcaactgg tatatcccgt gtgaagagaa tatattcatt attttggcgt gctttagcta
      841 atctttgagc aatacgttct gccaattgat ctgactctgg aatataaaat tcgctgtttg
      901 gatcaagaat atgattttgc atatcaataa taactaacat tttctttcct cctacattca
      961 tatcgtcatt ttattctttt taatagaagt tttttaaaat ataagcaaca ccagcttctt
     1021 cattcgtcag tgttacttgg tttgcaattt cttttacttg tcgctgtgca ttccccatcg
     1081 caatactcaa cccgctgtaa ttcaacatag caatgtcgtt ttcttgatcg ccaaaagcca
     1141 tgatgtcact cgattcgatt ccaaggtaat ccgccagaaa aacaagtgaa tgagctttag
     1201 tgatacctgt aggcgtgatt tctaagaaat gcggatcaga gaatactgat tggataccat
     1261 ctgcttgcag atctctttgt agcttctgta gtttttcttc actcttatct gttaatgcta
     1321 atttaagata gctaagagaa ggatcttcca acatatttaa aatttgatca aaagaatggt
     1381 tctgtaaatt gaaatgttca taataagggt catctttgac tagatttgat tcatcgaatg
     1441 tcagctgatc atcttgggtt tctcggctag caatgatgga tattttcgct tcttgagcat
     1501 agaagaaggc ttttctcagt gtatcgctat ctatttttga acgtctgaga actttcgcca
     1561 tttttccatc cttcatttca gcaatcagtg aaccattgga agaaatcaaa tagccaccga
     1621 ttcctaattc ggaaaaaata tctttagcag aaatgctgtt ccttccggta gcgacggtta
     1681 cgattccgcc attttcatca aatttccgaa gtgcttggat attttcttct ggtatctttc
     1741 catttcgatc aagcaaggta ccgtctaaat caatcgctgc tagtttcatt ttatcttcct
     1801 actttctttt tacatatcta ttttcctgtt accttaagat taaatgagaa tttaaaaaaa
     1861 tgaaactaac ttgctttgtc attatgaatt ttttcaaaaa acattcttaa gaaaaaggtg
     1921 gctatatata gtagtttttg gtcaatacct ttgaataaaa agccatgaaa aacgaatagt
     1981 tagcgcttac cgatgcgttt tgtgataaaa aaattttaaa atattcaatg aaaacaaagc
     2041 atatattttg ctttaaaacc aaatgaggaa tattctagat gtagaacagg ttagaaaaag
     2101 attagaaaaa ggagtgattt tgatggagaa gagatacggc gtagttcctg tggtaactgc
     2161 ttcagacgaa aattatgctc cttacttgag cgtgatgatc gcaactgcat tagaaaattg
     2221 caataaaaca agacgcataa aattttatgt gattgacgat ggtctatcag aatatagtaa
     2281 agaaggattg gaagaaacgg taaataaata ttcaagtaat gcaagtatcc aattcctgac
     2341 agtggaaaaa gatatctacg aagacttcct agtcagtgac catatcacaa ctaccgctta
     2401 cttaagaatt tctttaccaa acttattagc taaagaggat tataagaaag tcctttactt
     2461 agattcagat gtgttagtac tagacgatat cgtaaaacta tatgatgagc cgttaaatgg
     2521 aaaaacaatc ggcgctatta tcgatccagg ccaagtgaaa gctttggaaa gattaggaat
     2581 cgattccgat gacttgtact tcaattcagg agtgatggtg attgacattg atcaatggaa
     2641 taaaaaagaa attacagaaa aaactatcca ttacctcagt gaaaatggcg atcgaatcat
     2701 ctatcacgac caagatgctt tgaatgctgt actttatgaa gattgggaac aacttcatcc
     2761 aaaatggaac atgcagactt cgctgatttt tgaacgtcat ccagcaccaa atgaaaaata
     2821 tgaacgtcag tataaagaag gaaatgaaaa accttcgatc gttcacttta caggacatga
     2881 taaaccttgg aatacgttga aagatcatcc gtataccaat ttatacttaa aaaaattagc
     2941 acacagtact ctaacgaaag taggcgagat caatgaataa aaaagaaata gcagtagtcg
     3001 caagttgtaa cacaaaattc gtaccacatt tagctgcatt atttgtctca gtattagata
     3061 attgcaaccc gtctaaattt gttcggttct atgtgattga cgatgatatc gattttgaaa
     3121 gtaaacagct tttacgcttc tcagtgaaaa acgcacgaat gaactcagat gtggaattct
     3181 tgaaaatcaa taaagaattc tttacaaatg tggtaatcag cgatcgtatt ccagaaacag
     3241 cttattatcg tattgcgatt ccggaattgt tccgcggcac agaagttgaa cgtatcttat
     3301 atatggattg cgacatgatc gctttacaag atatctctaa attatggcgt cttgacttcg
     3361 gtgattcaat cgtagcagct gttgaagacg ctgggttcca tcaacgactg gaaaaaatga
     3421 aaatttcagc taaatcaatg cgttatttca actcaggttt gatgctgatc aatgtgaaaa
     3481 aatggttaga tgaaaatatt acgcaaaaag tattagattt catcgaacat aatccagaaa
     3541 aattacgatt ccatgaccaa gatgcattaa atgctatctt acatgaccgt tggttaccac
     3601 ttcatccgcg ttggaatgca caaggctata tcatggcaaa agcaaaaaaa catccaacag
     3661 cagcaggtga acgtgaatac gaagaaactc gcaacaatcc ttacattatc catttttcag
     3721 gacatgtgaa accgtggagc aaggattttg aagggccaac gaagaaatat tacgaaaaat
     3781 atgcagggat gacggctttc cgttgtgtag ctaaattccc taaatatcca aaatatgcaa
     3841 aagttcaacc aaaaacagat gtagttgtta aataatagaa gacaacaact gaagaggggg
     3901 agtaggaatg gaaattacaa tgtctaaaaa tgcagtagag acgttaattg aaaaggttgg
     3961 ggaaaataca aaaatcgcac tcgcgcttat caatgattcc gatccatttc taagggacaa
     4021 aggtgctttt gcaaaaggca gcttttttca aatcattcct tttgtttcgg aatttggaga
     4081 atatgcgact aaaatcgagc atccattatt ggacatctat acatctaaat tagagcaaaa
     4141 ttatttcggt aaacgattga acatggactt caacaaacag cttgacagct tttcattaga
     4201 aaatgaaatc gcagtactcg attataatat caaattaaag aactgcttct tcagctaata
     4261 gtttcgagaa agtccaaaaa ggaggtatac attgagatac tactttgtgg atgaagaaaa
     4321 gaatgtaata gaaacagatg aaaaaaaata taattggctc gtacttgata gtgcaaagcc
     4381 cgaagagatt gagcaagcaa tcgaagaatt cgagcttcct gatgatattt tcgtaggaac
     4441 cgaatatccg gaagaagttt ctcggatgga gcgcctttat gagacgaaac tagagcatcc
     4501 attttctttg gtagtgatta atctagatca gtcagataat cgtatcgaaa aaaattaacg
     4561 ccaatatctt ttgtactttc cgataatctc ttgattactt gtatcgatag aaaaaccgaa
     4621 tttgtggatc ggctgctgac aaagcatgga aatcatttaa actcgtttga aaagatcatc
     4681 acgtatacat tattagatat ttacacccat tacgtgaaag aactaagaga gatgaaaaag
     4741 cgaattgacg ctttggataa agcagctcgt aaaacaacgg aaaatgaaga actgtataaa
     4801 caggcagatc ttgaaagaga catcgtatat atcgatcata ccttaagaga tcaacgggaa
     4861 acaatggatc aattatggaa ttctgaaact ttcatcaaac gtttagacga tgaacagcta
     4921 ctctatgatg tccatttgag acagcgacaa acagaaaaaa tgatcgagat ctatcgagat
     4981 ttattagaga gtattggtga tctattcaac gggatgatgg acaataatct aaatcatatc
     5041 atgaaatatc tagattcagc tgcattaatc atttccgttc cggcgttgtt cgcagggatt
     5101 tggggaatga atacaggagg attaccgggt aaaagttctg ctctaggctt tatactcgta
     5161 gtctttggct ctttgatagc agcagtagtt ttaggttacc atttataccg gaaagattat
     5221 acaaattaaa gaatctattt aaaacaggta tcaaacaaag aaatttgttt tggcaataca
     5281 atttaaaaac taggaggaat acagcaatga cagaaccaaa attaatcgac ccgcgaaact
     5341 tgtaccatac ggagaaattt cctaaacaag atcaggatac accagcttta cagcagaata
     5401 tgattcctgt tcctgattgt ggagaagaat cctatgaagg caataatcaa ctagaaaacc
     5461 gccgtgtact aatcactggt ggagattcag ggatcggtcg tgcagcagcg attgcatttg
     5521 ctagagaagg ggcagatatc gctcttcaat tcttcccagg agaagaaaaa gatgcagagg
     5581 aagtagcaaa atacgtgaaa gttgcaggac gtaagattgt cttactacct tttgatcttc
     5641 gtgacgaaca agcacctaaa gaaatcatag ataaagccgt gagtgaactt ggcgggctag
     5701 atacgatggt actaaacgca ggacagcaaa tttcttgtca gtctattgct gagttaccac
     5761 ttgagcaagt caaagacaca tttatgataa acatcatcgc tatgtttgct ttagtgaaag
     5821 aagctgttcc gcatatccca gcaggaggag caatcgtaac aacaacttct gttcaagcat
     5881 tcaatccaag cgaacattta ttagattacg cagcaacaaa agcttcaatc gctaacttta
     5941 cgatcggttt agcaaaacag cttgcaccta aaggaatccg tgtaaatggt gtagcacctg
     6001 gtccaatctg gacaccatta caactagacg aaggacaacc ttctgattcg atccctgaat
     6061 ttggtcagca aagtttacta gaacgtgcag gtcagccagg agaattagca ccagtttatg
     6121 ttttcttagc atcgaataaa gcaagttatg ttacagccca aatttacgga gtaactggtg
     6181 gagaagcgat caacttataa gaagttgatc gtttcacccc tatgaggagg tgcgaaaatg
     6241 aataaaggtg taaaaacgat cggagtgatc ggaacattac ttttgctatc tgtgcttttg
     6301 tttgcgatac tattaagtgc aacctatcca ttgccttttc agctagagaa gtttcgattc
     6361 ttttccatca ctaattcata cgtgcaacaa tatgtatttt ggcttgccgt tgcatttgct
     6421 attttgacaa ttatcacgtt acttgttttc ctgttttatc caaaaacaat cggaaacttt
     6481 ctactgaaac atggtgatgg ggagttgacg ttggataaaa aagcaattga aggaatggtt
     6541 cgttctcact tgcatgaaga tgaattcatc cattcaccaa aagtaaatgt caaagcaacg
     6601 aaaaacaaga tcgccgtcaa tgtaaaaggg gagttgaaac gaacttcagc actcattggt
     6661 aaaacaggaa cattgatgaa agaaatcgaa aatgaagtac aacacatatt gggaacaaaa
     6721 gagccagtga aagtatcggt gaaatacaca ggctttgaag aaccagctaa acgaagcaat
     6781 gaccgcaaac gagtagaata gggggggacc aaaaatgaaa gaactatttt cgacatacaa
     6841 gctccctatc atctttgggg tacttggatt gatattagcc gttttatgga tcaccgtggg
     6901 ctttttcaag accttattga tcttgatcat ggcagcgatc ggcgtcgcta tcggttttta
     6961 tctgaaacaa acgaaaatct tagatcacta ttttaaatct taggaggaaa catccatgaa
     7021 taacaataac aaaaataata acaataaaat gaacaaccaa aaaccagtgt ctgcacatcc
     7081 agacccaacg acaccaaacc aatcaaatgg tgtgaacgat gaaaagaaca aaacagcacc
     7141 agtatctgca catccagatc cagtagtccc taacgttcaa caaggagtag aagagaagaa
     7201 acatgatgca gaaaagcatg cacctcatca tccaggaact ccagaatcta aagttccaga
     7261 acaacatgat gcaatcgatc cttctaaacc tgtggaagag caaaaacatc cttctgacca
     7321 tgcgaaagca caagaaaaac ttagttctga ccacacaaac ggacaaggaa aacttggttc
     7381 tgatcataca aataaccaag gaaagcatga ttctgaacag gaagattcaa tgcgcggtga
     7441 gctgaattat gaagataaag ttgtgcaaaa aatcatcgga atcgcaattg aacaagtaga
     7501 cggtttatta tctgcaaacg gtggtttctt ctctaatgtg gcaggaaaac ttgtgaatac
     7561 agataatgta acggctggga tcgaaacaga agtcggtaaa aaacaagtag cagttgatat
     7621 ggatgtcatt gtggaatatg gcaaagatat cgaaaaaatc tttgaagaaa tgcaagaagt
     7681 aatcggcaaa gaagtaaaaa atatgacaca tttagaagtg atcgaagtca acgctaacgt
     7741 agtggacatc aaaacaaaag aagaatttga aaaagatcaa gaaacggtgc aagacaaagt
     7801 aactgacgca gcgaaaaaaa ccggtgaatt tgcttcgaat caaacagata aagtaaaatc
     7861 agcagctgga agcggcgcac aaaaagtaaa agaaaataca gaaccacggg ttcagtaata
     7921 aggaagtaaa acattaggag gaacgaaaca tgggatttat ttggtcactt atcgtcggag
     7981 gaattatcgg agcaattgca ggagcaatca cgaataaagg ttcttcgatg gggattattg
     8041 caaatgtcgt agcaggttta gttggatcag cacttggtca agcattatta ggttcttggg
     8101 gaccaagtat tgcaggaatg gcaatcgtgc catcattgat tggtgccatc attttagtac
     8161 taatcgtatc attctttgct cgaaaactgt aaaaagactt ttaaaaagag gtcgtgaaaa
     8221 agctgttctt catcaagtaa taagaacagc caaacaaaaa tagcttctca tatttttcat
     8281 ttggttgggc atgttatcga agatgcaagc ttttgaacac tgtttatacg gaataagagg
     8341 ctgtgacaag acttttgtca cagcctctta tttatgcggg caaattccca attagatttt
     8401 taaaagtttt tccttaaatg tgtctttatt gatacagaga agcttcttta ataaaacaat
     8461 gcctccctaa attttcttga gataggaaag gtgaacatac aaaataatac gaccactttg
     8521 aaaacccaga tgatccacaa atggatcgta tgatactgat gaagtaaaaa gcaatggatc
     8581 agaaactcaa agagattgaa aaagacaagg aagaaataat atctcttttt tactcttgtc
     8641 tgttttagcc aataatagct cgtaaagtaa tctagacaaa caaatagaag taaacaaagt
     8701 ttcgtaagag cagcaatcgt atcatgttgc tctgctagac gattgacgag caggaaaaat
     8761 gttggtaatg gaatatagat cacgagtaat gaaagaaaaa agtaaacaat aaatggcata
     8821 ctattcctcc taattgtgtg agttcgccct cattttaaaa taacg
//
LOCUS       DAFTHM010000105         8812 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFTHM010000105 DAFTHM010000000
VERSION     DAFTHM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.105"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..147)
                     /locus_tag="L7C88_002371"
     CDS             complement(<1..147)
                     /locus_tag="L7C88_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="catalyses the hydrolysis of terminal non-reducing
                     alpha-D-galactose residues in alpha-D-galactosides;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBP9559171.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLM"
     gene            complement(179..1003)
                     /locus_tag="L7C88_002372"
     CDS             complement(179..1003)
                     /locus_tag="L7C88_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9559172.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            complement(1019..1915)
                     /locus_tag="L7C88_002373"
                     /pseudo
     CDS             complement(1019..1915)
                     /locus_tag="L7C88_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            complement(1998..3107)
                     /locus_tag="L7C88_002374"
     CDS             complement(1998..3107)
                     /locus_tag="L7C88_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBP9559173.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            complement(3401..4426)
                     /locus_tag="L7C88_002375"
     CDS             complement(3401..4426)
                     /locus_tag="L7C88_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9559174.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            complement(4671..5942)
                     /locus_tag="L7C88_002376"
     CDS             complement(4671..5942)
                     /locus_tag="L7C88_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBP9559175.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            complement(6226..7173)
                     /locus_tag="L7C88_002377"
                     /pseudo
     CDS             complement(6226..7173)
                     /locus_tag="L7C88_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            7185..7658
                     /locus_tag="L7C88_002378"
     CDS             7185..7658
                     /locus_tag="L7C88_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBP9559176.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            complement(7831..8385)
                     /locus_tag="L7C88_002379"
     CDS             complement(7831..8385)
                     /locus_tag="L7C88_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBP9559177.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
BASE COUNT         2821 a         1682 c         1296 g         3013 t
ORIGIN      
        1 cattaaattt gattctttta gtcgtttttc atcaatatcg tacaatgcaa tatgtgcatc
       61 ttgtagactt ggagttaaca tcgcatcgcc taatacgttt tttgcaaaaa tagtacttcc
      121 tgcaccaata aatgtaattt ttgtcatgta cttactctcc aatcactaat taatagtttt
      181 ataatttact acctgttgta gcaattcctt caatgaattt tctttggaaa acgatgaata
      241 tcacaactat tggccaaatt gctaataacg aacctgccat taattgtggg aagttcgtgg
      301 catattgtcc ttgtaagttt gctaatcccg gagctaaagg catcttatca attgaagtat
      361 tgacaatcaa tggccacatt aaatctttaa atgcaaacaa cgctgtgaat attccaagtg
      421 caaccaatcc tgatttagca agcggcaaca taattttgaa aaagatcgtc caaatattgg
      481 caccttctaa ataggccgct tcctccaatt catcaggtaa acctaagaaa aattgtctta
      541 ataaaaacgt accaaacgca ctaactaccc ctggtaatat taatgctgga attgtattta
      601 aaatacccaa tttttgtgct aataaatact gtggagtaat aaaaatggaa ccgggaatca
      661 tcatttgaat aagtactaag ctgaaaagga tatttttccc tggaaaactt agacgcgcac
      721 aagcatatgc agccattgct gaaaataaaa ccgagccaat cactcgtcca acaaccatta
      781 aaaatgtatt gatataaaaa gccatgaatg gtaataaatc aagtacttgt tgatagttac
      841 ttagctgaaa tttctcaggg aaaattgtag gtggaatttg ggtagattca accaacgttt
      901 tccctgaagt taaaatcatc caaataaaag gtaatgccat tgcaatacca cctaaaataa
      961 gcatgatatg gattggcgca tttgaaaaaa atttattttt cataatttga tagcctcctt
     1021 aatagtttac ccactttttc tgcaacttca tttgaattgc agtaataatt aatataatca
     1081 ctaaaaggaa cataacgatt gccgaaccat atcccttgtc atttaaaata aatgaatgtt
     1141 tatagaataa ataggctaat gattgtgatt taaacatggc ggtactatta ggagtaatca
     1201 tcataaaaat aacatcaaat acttggaaag cattgataac tgttgttaca actacaaaaa
     1261 ataatgttgg tgtaactaat ggtaacgtaa tgttgaaaaa ctgctggatt ggactagcac
     1321 catcaatttc cgctgcttca taataatctt taggaatttc ttataagccg gctagtaata
     1381 acaccatgtt ataaccaata gcactccaaa ctcctacaat gataatagaa taaatcgcaa
     1441 tcgatggatc cgttaaccat gctggtccat cgagacctat tttagccaac atgttattaa
     1501 tcagtccata atcattattg aacatccagc gccaaatcat tgcgactgcg gatggtgcag
     1561 caacgactgg tagaaaataa attgtccgat aaatcgacaa tcctttaact tttctattca
     1621 ttaaaactgc caccaacaag gataatacaa caatactagg tatcgaaacc actgcataaa
     1681 ttaatgtgtt taataaagac tgaaaaactt caccgtctgc aaacattttt tggtaatttc
     1741 ttaatccgac ccattcagta tcaccgaacc ctaccgtttt ttgaaaactt aaaattgctg
     1801 tttgaattgc tggccatata tttaataaaa ttaatcctaa tgccgttgga aaaataaaaa
     1861 tatagcccca tatcacttga tctttacgat attttccaaa aattcgattt ttcataatat
     1921 cccccttttt ggtattcatc cattaatata cagacgaaat agaatccttt cgcctgtata
     1981 ttgtataatt aactaattta atttccgctc aatatcgcat tgacttcttt ttcaatttga
     2041 gcggttccat cttcaacagt tacttcacca gacagaatac ggttaataat ttgaacttct
     2101 gcttgttcag ctcgtaatcc atctttattg tatggacgag ggactccata ctccaacatt
     2161 tttccaaaag cactcaaatc aattgtatct gaagaagcag cccactcgtc ttcaaagcct
     2221 tttagtgctg ggattgatgc ccccgtttcc gcttggattt tattggcgtc ctcactagct
     2281 aaaaatgcca ttagtttttt cacttcttct gggtattttg tactcgcact ggcagcccaa
     2341 ccaagtccat ttgtaattgt tgcattaact tttcccttag gtaacacggc agaagcaaca
     2401 ttttcaacta gatagtcatt tttcaaaaat cccggtgcaa accagtttcc ttcaatcatc
     2461 attgctaatc tacctgattg aaaacgactt aacttatcag gatcttgtaa ttctgtaatt
     2521 gttggtgaag catgatcaac aagtgcaata tctcgataaa aagctaaagc ttcttgtgct
     2581 tctggggtat tcaaacctga ttttgtattg tcatcggcaa atacttctcc cccattttga
     2641 taaataaatg gccagtagcc agtctctgtt ccaatatgtg atgcaaaacc atagatgcct
     2701 tttgattcat ctgttaaatc aattgcagct tgtctgagtg tttcccatgt ccatgtttca
     2761 tctggataat cgacacctgc attatcaaat aattctttgt tgtaccatag ccccactaca
     2821 gaagcatctt tagggattgc gtatagttcg tcttcaagcg tatagaaatc agcaattcct
     2881 tcagtaaagt ttcccatgtc aatatcattt tctttgataa catcatcaag tcccatcaaa
     2941 gcattctgtg acatatattt ataggattcg ctagagtgca tggttactac atctggcata
     3001 ttacctcccg ttgttgcagc ttctaattta acccaatatt gatcccaagg cgttgtctcc
     3061 atttctactt tgatatcagg attttgtttt tcaaattcat ctaacatttt tcttagtcct
     3121 ggagcttggt cagtatctca actcgcatag cttaaagtta cttgcccgtc tttagaatta
     3181 ctatctcccc caccacatgc tgcgagtaat gtcccagtta aaacagctat ccctgttaaa
     3241 gctatttttt tgaaatgttt catcttaatt cctcctgttt tgaatgcgtt ttctttttgt
     3301 taacaacacc ataactgttt acttaatgtt ttgtcgagat tttttactaa aaatattagt
     3361 aaacaaaaaa gtaaacaccc ttttttggat gtttactttt ttaatcgata tttttttcac
     3421 tttctctaac aataatatta ttagaaacaa tcactttgat cgaaacattt ctaacttctt
     3481 ttattcgttc attaaccatg cgaactgcta gttttccaat ttcttctgta ttcacattca
     3541 ccgtatttaa tgcaggtgtt aaaaattcag caacttcaat attatcaaaa ctcacaatcg
     3601 aaatatcttc tggaatatgt agaccatttt tttgaagtga acgataaacc cccacagcaa
     3661 taggatcatt tcctaccatg atagcagtcg gcaacttatc tttagcatgt tttttcaaaa
     3721 gtaaatctgc tgcctgcatt ccgtcaagtg tggtccagcc ttctaaataa atttgactat
     3781 atttttctaa tcctttttgt ttcatccacg tctcataggc tatttttcga taatcatcat
     3841 ctgacacgtg tttatttcct tggctatcta aacgaacacg tcctcctccg ataaacgcaa
     3901 tgtttcggtg tcctttttta tacaatcgat ctaaatgctg attcgttgct tttgttaaat
     3961 cagtataaac tgcatctact tcagcttcaa tactagggtc atcaatcact acgacattcg
     4021 aattaattgc tgatacttct tcaatcacag aagatagcac ctgcccaata atcaacacac
     4081 cttgacattt tagcaaatcg tcttgctcca acggtgtttc tgacaaacga ataattttct
     4141 tcaaattgac tttgctttgt tctgcttcga cttgaatccc tctgcgaatc gttcgaaaat
     4201 agggatcttc caactcatct acttcagaaa ctgtcgttat taatgcaata tttgttaaat
     4261 tttttgcaac gggacttttt ttgacataat gataaaaatt aaccgattct gcaatctttc
     4321 gtttggtttc atcggttact gaaagtgtcg gatcctcatt tagcacgcgc gatactgttg
     4381 caatggacac acccgcccgt tttgcaacat ccctaattcc taccataata gctcctcttt
     4441 tcatatttga aagtgtttac taacatataa tcatacattt tgaaaataag caaatttcgt
     4501 taaaaatagg cactgtaatc ataattaaaa acaagaaaaa atatccgaac aatttagagt
     4561 aaataatgct aattctagtg aatttgcgac gaggaactgc tagatcacag ttcattctct
     4621 ctatcgttcg gatattttat tgttaactat acttatttca cagagctttt ttatttgatt
     4681 ttgtgaacag agtctcgaga aatcaattct ccctctaata gtagtacttg attttttatt
     4741 tcttcttgtt tggccagtcc aatcagttgg tgaaaagcaa tcgccccctt gttacctgga
     4801 tttagtcgta ttgttgtcaa cgcaggatcc attaattctg caaaagtaat atcatcaaat
     4861 ccaataatcg ataattgttc catcactcgt ttattcttat tttttaaaaa ttttactaat
     4921 ttagccgcta aataatctcc agtaacaaca attgcagtaa attcagctaa ttcttgataa
     4981 attcgctcaa attcagagtt gttatatatc caatgcgatt taaaggttaa atgatatttc
     5041 tttaatgtat cgatataagc ttgatgtcgt tcttgaataa cacttggttc acctacaatg
     5101 tagtcaaaag aaagaaacgc tattttctca tgaccataat gaatcaaatg ttccactgcc
     5161 aatgtactag cttggtaatc atttgtattt acaaataaac gattcatttg ttgttcaagt
     5221 tctcttaatg tctcttttga aagatgcgta tcaatataaa caacaggacc atcaaaaacg
     5281 ttatttaatt ccaaaaattc ttttacacgt acaccaacaa caatgaaccc ctcaaaacgc
     5341 caatttctct gaatagtttt aacatcttct gctgaattaa cattatgcac caatacaaaa
     5401 taaccatgat tctttgcctg ttcctcaatt ccagacaaaa cttctgcggt aaatggatca
     5461 gaaaatacaa aatcagcatt atcaatagcc gaaaaataaa gcaatcctat taaaaatgca
     5521 atcgtcttac cgattccctg acagacagaa cacattccac taggatcatt aaatgaataa
     5581 gcatttgcat atcctaaact aggtgttgca aaacatgaaa acaacacacg aaataacgca
     5641 ttgatgttag taatcgtccc taacgttgag cgcgcactgc caccaatctt cttttgattg
     5701 accacaatcg ccgtagaaag attatcaatc tcatcaacct ctggacgact gtatttaggt
     5761 aaaaataaac gggtaaaact atcataggtg tcattcagtt gacgaccagc ttcttgggta
     5821 atagtatcaa aaacaatcga tgattttcct gaaccagata cgctggtaaa aatactaatt
     5881 ttatttttgg gaattttgag actgacattt ttaagttgtt tctcttgcgt ggataatttc
     5941 aatatactcg ttcatttggt actccccttt attttgaaat agttgagaat gtttcaatga
     6001 gacacggtat ttttggcaga tgtttagttt acctagaaag aggtataaaa atcaagaaaa
     6061 aaagagaggc tgactcataa gtagttttat tagtcgaaaa tgatagttta taaaaatagg
     6121 aaccgcatca aatcaacatt ctttagaatg gatttgatgc gtttttcttt attttttgac
     6181 ttatgagtca acctcttact cttcgtcatg gatttgatta gctaattatt gctccacttg
     6241 ttcacgaatg aaatttaagt actgcggtaa aaataaagga atttcttcaa agcgtggact
     6301 ttgattttca tacgcttttg catctaggtt tccttcccct gtagcaattt caatcaataa
     6361 ttgatttggg tcacgataat aaagtgatac aaaaaattca cgatctttta ttcctgaatt
     6421 tataaaattg cgctcttgta attgtttgtc gatgcgttgt aaatcagatt tattttctac
     6481 gccaaacgca acatgatgga cgctaccaat cccttcaatg gcaactggat tctcacgatc
     6541 ttgaataatc tgaacttctt gatagaactg agtgtcttga ttttctaaga ttgtcactcg
     6601 ttgatgaccc gaaaagaaac tgacgtattc tttgtgctac cagcctaccg acaataactc
     6661 tcgttcagtc gcatcggaat attgtacgcg tagttgaatg gcatcaattc ctaaaatggc
     6721 atgctctgta gggatctggt ctgtgacata cgggaaataa tcatcaatat cttcaaattc
     6781 gcgtaaggga actaaagcta atcgtgttgc atctggccct tcaaaacgta agataggtcg
     6841 tccagaaaat gattcgattc cataatggca aacgccttgt gtttcaaaat atatttccca
     6901 aaaatgcaat gatgcttcgg aaggaacttt tagtatcgtt cgttcaatcg tattggttcc
     6961 aaaaaactgg ttgttccctt cttgtacttc aaaaaaagtc agttcagttc ccacacggtg
     7021 gtgattatct gaaaaaaaca ggtgatacat ggtatgatcg tcttgattaa ttgttttcat
     7081 tagtaatttt aaaccgagta tattatgata aaagtcaaat gtcggtcgaa taaagcgatt
     7141 cacaatagaa atgtgatgaa tacgtgcggg cataatatct aaaaatgaga atcaaaccta
     7201 taaaagatgg tgaacaactt ttgttttcat cagaagaaaa taagcccctt tatttagact
     7261 atgtaaatca caatttgaaa atcatcatta aagagaataa cttaaaacat atcacacttc
     7321 atggttttcg tcatacccat tgtagtctgc tctttgaatc tggtgcgtct gtcaaagaag
     7381 tgtatgttcg acttggacat acagatatta aaaccactat ggatgatata tacacccata
     7441 tcgcgaaaaa gcagacagag gaaacggcaa ttcgttttgc agatttcatg agttctacag
     7501 aggaaaagca aggaagtttg cagaaggtca aaagtatggt caaaaacgaa aaaagcagac
     7561 tatccctatt agatagtctg ctaaacgttg agttatcagt atttttctta ttccgcagcg
     7621 tttgcgtttt tgagaccgta ttgattctct ttttttaatt tcatcctttt ccaacctaaa
     7681 aatgttattt aattacttag tttatataac acgaacctat accaagtacc agtaacccca
     7741 gcttttattc cgcgaacttt atgaaataaa atcgttctag ataaaaatag cttttaatct
     7801 ttgtctttac tgtttataaa aatttttaaa ttatacacct agtttaaatc cacgaagtga
     7861 tgctcctatt tcatcttcag ttataccaat gtaccttttt gtaattgctt gcgagctatg
     7921 attaaaaata aacattaagg tagcaatgtc tctagttttc ttgtagtagt gatacccaaa
     7981 agtttttctt aatgtatgtg ttcctatatc atctcgtcct aatttttctg ctatatctgc
     8041 atatatctga tagacacgat cccttgttat atgtcgacct tgttgccgac tcggaaataa
     8101 ccaatcattt tcttctttac cttcagtata taataaaatt tcttctctca aattatctat
     8161 aaaaatcggt tttcgcttac ctgttttatg ttcaacaata ataggcttac ttttgcctcg
     8221 tatatctcca acttttaatc ctataatatc tgacatacgt aacccattat tgattccaaa
     8281 caaaaataaa aaactatctc tttccggatt acttgttctt cttagccaaa actgaaaatc
     8341 ttgtatctct tcatttgtcc ttaacggttg tacattatag ctcactattg tttcccttct
     8401 taaaaatatt ctgagttaat gattatgtat atattttacc ataatcatta acttatatat
     8461 ataaactttt gaaagtcaat aaaatcaagg gatttagttt atgattttat atcatttcag
     8521 taactcagaa tattccgact tttttgtaca aaaaaattaa ccttacttat atgaagattc
     8581 taagctctta tttaaatttt agacgggcag ttatccgtag aagttcttag aatagctaat
     8641 ttacataatt aaattatatg aaatttaagt ttgaacaata tactaagaac tccccttact
     8701 ataaagtgaa ataaattagc atatgaataa ccgtgctacc aagcttttca ttaataaaat
     8761 atttttatta atattttata actttacgca agatcataat tttgtcggga gc
//
LOCUS       DAFTHM010000106         8745 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFTHM010000106 DAFTHM010000000
VERSION     DAFTHM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8745
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.106"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(224..307)
                     /locus_tag="L7C88_002380"
     tRNA            complement(224..307)
                     /locus_tag="L7C88_002380"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(271..273),aa:Leu,seq:cag)
     gene            835..1335
                     /locus_tag="L7C88_002381"
     CDS             835..1335
                     /locus_tag="L7C88_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9559178.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(1525..1869)
                     /locus_tag="L7C88_002382"
     CDS             complement(1525..1869)
                     /locus_tag="L7C88_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBP9559179.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2023..2943)
                     /locus_tag="L7C88_002383"
     CDS             complement(2023..2943)
                     /locus_tag="L7C88_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBP9559180.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3130..3621
                     /locus_tag="L7C88_002384"
     CDS             3130..3621
                     /locus_tag="L7C88_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBP9559181.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(3645..6020)
                     /locus_tag="L7C88_002385"
     CDS             complement(3645..6020)
                     /locus_tag="L7C88_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBP9559182.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6346..6972
                     /locus_tag="L7C88_002386"
     CDS             6346..6972
                     /locus_tag="L7C88_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBP9559183.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            6995..7699
                     /locus_tag="L7C88_002387"
     CDS             6995..7699
                     /locus_tag="L7C88_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBP9559184.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            7891..8724
                     /locus_tag="L7C88_002388"
     CDS             7891..8724
                     /locus_tag="L7C88_002388"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBP9559185.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
BASE COUNT         2652 a         1669 c         1545 g         2879 t
ORIGIN      
        1 ttccttaact atcgtttgcc agtatttctt gtatcagaat ctataaatct actatttgaa
       61 tcaatctatt aggttttaaa ctgtcccacc ttcacacaaa ttttttttga tttatttgaa
      121 tctggttccg ttgtttaaaa tttttcctat attcttttag ataatatgtt attttctttc
      181 tcatcgctcc aggtgtacct tctctttata aaaaaacaaa ttatgcggct aagaagactc
      241 gaacttccac gaggtcaccc tcactagcgc ctgaagctag cgcgtctgcc aattccgcca
      301 tagccgcatc acatctttta gtttaggatt acatgtgttt tttgtcaaga acatattttt
      361 gttctttttc atttctgtac gccctccctt atgccatcta cacaaataat tcatccgagc
      421 aactccatca tctattgagg gttggtgaaa aaatctgttt tatccatatg atcgatttca
      481 atgttaaacg aacgactctg ggattagtaa ctattttatt tttttcttca tttctttttt
      541 cctctttttc tcgattcagc tatcttcttt catttggata ttgattattt cttctgttga
      601 ttactatcct tctggaattc tagacgctga agtaattcac gttttctttc ttctagagat
      661 cataagtaac gaatgaacga acttcaaata atttttttat tgtaattcat atttgtattg
      721 ttcgatgatt cttaatacga tatgacacaa taaataaaaa taggcatggc tatttacaac
      781 aatagtgcta tagtagaaaa caaatgaata aggttactta aagaggtgaa tacgatgaaa
      841 ctgatcaaac tatgggaagc agatttaaag aaagcttatc agctacaaac tagctttgga
      901 ccaaatgaga gtggatttat caacaatgct tatggctata catttgctga atttttagat
      961 tatgtaaaaa aatgcgaaaa aacgtcttta ggaatcgatc ttcctgagag ttacgttccc
     1021 gcaaccgtct ttattttaga aagtgatgaa catgagtatg taggaatttt taatttgcgc
     1081 cataaactga acgaaacatt aagaaacggc gctggccata ttggttacgg catctcccct
     1141 aattatcgta aaaaaggata tgccacacaa ggattagcat tagtactaca agaggcaaaa
     1201 aaaatcggca ttgatgaggc acttttgtct gtaaataaaa aaaatcttgg cagtcttaaa
     1261 gcacaacaaa aaaatggggc tgcgatttat cgtgaagatg agaaagaata ctatacgaaa
     1321 atcaaactga tgtaaaaaag aaggattcca aaaggaaagg gatttgaatg tcctttatca
     1381 atagaacaca tttatttaat taacttataa tatagcagac aaaattttat aaacaaagaa
     1441 accttttatc tcttttcttc tagaaaggat aaaaggcttt tttgtttttc ctatttgctt
     1501 ctcatagcta gtcagccaag atttctatcg tatccccaac gcaatccgtg cataacggct
     1561 catcttatct gtcgtccatg ctggatacca gactagtttg acttctgctt tcgttacttc
     1621 tggcacttct tttaatgcgt catggataga ttctgttaaa atatctgcta atggacagcc
     1681 catagttgtt agagtcatct taatgactgt ttctccattt tcaggattga attctatatc
     1741 ataaatcaag cctaaattga cgatgtcgat tcctaattca ggatcaatca ccatttccaa
     1801 ggcagcaaga atacgttctt tgattagttc tatttcttgt ccagaccgtt cttggtttgc
     1861 ttcgctcatc gtacgacact ccttaacacg atttttattt atcatactct ttttttagct
     1921 gcttgtaaat gagaatttag aagtaagatt ctcgtttaaa tttataaaaa tgttcttatt
     1981 agatgtaata gattaaattt attctaaaat aaacctgatt cctcattttt tttgtgaacg
     2041 attttttatt tctggcaata cgccagttgt tcgatacatt ttttgttcgt tttcatttgc
     2101 aaaccggcca aatactgaat gagttggtaa aatattgata aatgcatcgt cgtcgatttc
     2161 atgaacgatc tgatcaagat catacatttc gtagcgggtg atgaccatca tgatcatgtt
     2221 cccttgtttt tttgaatagc caccgacaga cggcagtaat gtcattccac gtaccatccg
     2281 ttttgctagt tcttctgtta cctcttctgg cttgacggta acgatcattg ctgttacttt
     2341 ttgatgactc gtgtggatgg catcaattac ttgagtcatt gcataaatgg aaataatcgt
     2401 atacaaggca ctttcccagt taaagaagaa gcctgcgatg actacaatga taccatttag
     2461 aatcagcatg tagtttccga ctgtttttcc agttgtttgt gaaagtacaa gagagatgat
     2521 atccatccca ccagttgtaa agcccatttt taaagataat cctacgccaa gacctaataa
     2581 aacaccgcct actagggcat tcatcaaaat attatcagtg atctgtccga ctggaagcag
     2641 catcgtcatc accgatacac atacaacatt cacaaaacta aggatcgttg ctcgttttcc
     2701 tactttgaga aaccctaata caaacacagg gatattcaaa agaaaaataa atgttcctgt
     2761 gtctatcttg atatgaaacc attcatataa aagcgaggaa atgatttgag cgatcccatt
     2821 catccctgca gaaaagacat tggctggaat caaaaaataa tttaaagcga ccgcagcggt
     2881 caatccggtt atcaaaataa ccactatttt ctttaatctt tcatttttat gatacgcagt
     2941 cataatttta ctcacaagca cctctcccct actttggtat tccaaatgta agaataacag
     3001 tttatctatt aaaataaaat acttcgaact caaatgagaa gaattttagc aaacaggtaa
     3061 gaatctgccc taatcctatg ataagataga tgtatggtaa atatttatat gtatatcagg
     3121 agggttccta tggcaaaaga tgctagcttc gacattgtat cagaagtcaa tacagaagaa
     3181 gtaaaaaatg cgattcagca aacaacaaaa gaattgtcca atcgctttga cttcaaggat
     3241 tctacagtag aaatcaaatt agagaacagc aatctagttg tattgagcga tgatgatttc
     3301 aaaatcgaac agatcaaaga tgtattattt ggtaagctga tcaaaagaaa tgtgccaatc
     3361 aaaaatatcc atttttccga atcagaacac gctctaggtg gcaaagctcg acaaactgcc
     3421 gatttggtca acggaatcga tcgtgaaaac gcgaagaaaa tcactacagc tatcaaaaat
     3481 gaaaaactga aagtaaaagc acaaatccaa gaagatcaga ttagagtgac aggtaagaac
     3541 cgtgatgatc tacaagctgt gattgcttta ttacgtaaac ttgacttacc aatcgagttg
     3601 caattcacta actatcgtta atcaaaaaac gaggctgacg tctgtcattc ctcgtttttt
     3661 tgatttactg cttcttttga taaccaaaaa cgctgtattc cttcttccaa ttccccaaca
     3721 cttcgtactt ctcttgctgt ttgccaatgt tgtgggaata aacgtcgata agaaaaacta
     3781 gaaaatcgtt gatctgccaa tacaacgatt ccttgatccg ccatgccacg aatcactcga
     3841 ccaccagctt gcaagacttt gttcattcca ggaagctgat aagcgtaagc aaatccaagg
     3901 tgttccttct catcataata tgatttgatc agttcctgct catgattcat ctgcggcaaa
     3961 cctacaccta cgatcatact gccgatcaat cggtcccctc tcaaatcgat tccttctgaa
     4021 aaaatcccgc caagtacgca aaatccaatc aatgtttcag cgggatttgt ttgaaatttt
     4081 gttaaaaatc gttcgcgttc ttcctcattc atgtccgttt cttggattag cacattgctg
     4141 tcgggatatt gctgtctgaa tgcttccacc gcaagatcta aatattgata agaaggaaag
     4201 aaaacgaaat aattcccgac ctttccatca gcaaaagcat gaatcgtctc tactaatttt
     4261 gccagactgt gttccctttt tcgataagtc gtctctaggt aatttgcgat gaaaacttgc
     4321 tggtttcctt ctgggaaagg actcggcagt ttgtaagcca gacttttttg tccccccagt
     4381 gtttcctgat aataagagag tggtgaaaaa ctagcagaaa aaagaatact gctttttcct
     4441 ttatccaacg actgctcaag aaacaagctt ggatcaatac aaaactcttt tactatcaga
     4501 tcgcgatacg ttttttcgac tgttgtttcg tagtgatcat cataaaattc actgaccttc
     4561 aaaaaatgaa gcaaatcaaa ataataagga agcaattgtt cttgtgatgg gtgctcagga
     4621 aattctgcca gccattcttt aattttttcg cttaattgat aacctgcctt tactaaagat
     4681 tcagccggtg ctttttgatg atgataatcc caatgatctt cttttgctat ttctcggatc
     4741 gaatcaaatt cttttaatag tttgttgaaa cggcgatgaa gttttttgaa ttcctttggt
     4801 atagcttcct tacttcgttt cgttttttca taagatagtt ctgccgaata catctctcgg
     4861 gaacgattca ccaaattatg tgcttcgtca atcaaaaaca gatagtcctc gtttttttca
     4921 tcttcaaaaa aacgtcttaa ataaacagtt ggatcaaata aataattgta atccccaatg
     4981 attacgtcac accagatact gacatctaat gatagttcga aaggacaaag tgtatgcttt
     5041 cttgcataag tttcgatgac ttcacgagtg atctgattct catgattcaa aagatcccat
     5101 aaaccttcat taatccgatt gtaataacca ttggcatatg ggcactgatc tggattacag
     5161 gtcgtctcat ctaaaaagca gatcttgtct ttcgccgtca aagtgacact ttttacttca
     5221 gctcctgtat cttttaatgc tgtcatagca tcttcagcta cttgtctagt tattgtttta
     5281 gccgttagat aaaagatctt ttctccctct tcttccccta cagctttcaa agcggggaat
     5341 aacgtagaga ttgtttttcc tgttccggta ggtgcttcta caaacaattt ctgtttcgta
     5401 cggatcgttt tataagcagc taccgctagt tcacgctgac ctttcctata ctcatcatgg
     5461 gggaatttca aagccatcaa agaggcattg cgtacagtgc gccagttttc ttgaaaaaca
     5521 agccattctt tataatcttc agtcagcttt ttaaaaaaag tttctaactg ctctcttgtc
     5581 tgatgttcaa cctttctcgt gatcacttct tctgccgtct ggaagtaagt caattgcaga
     5641 tttatttctt gtaaatcatg ttcttgacta tagatatagg catacaccct tgcttgatga
     5701 aagaaaagtt ccacttgttc tggttctaaa tcttcaaatc gtggttcgga ggttttgatt
     5761 tcatctatat aataaatacc gtctcttttg aaaataccgt ctgcacggcc ttcaacgatc
     5821 aggtaatatt catctaattg aactgttgtt tttaaaaaga cttctttttc atagttttct
     5881 cccgcatctt tttggagctt gcggtggatt ctcgctcctt ctaatgcagt atggttactt
     5941 tttttacgat tgtcgatact tccacgtcgc aaaataaatt ctactaagtg ccgcacagat
     6001 atttttgact gtttgatcat ttccaccacc tctttctctc taagattacc tgaaaaaacc
     6061 tagtttagca aaaagagctc tctttccaaa cataaaaaaa caccctgctg attaggcagg
     6121 gatataggat atagaatttg gatttttgga tgaatctaat gtaacaagga catattaaaa
     6181 tgctatgaaa acttactttc cttctcttta gaatatccaa atacttttca tatagtctga
     6241 taattcagat aagtaaagag aaataagtac ctgtttttgt ttcctagcaa tgaatgcgtt
     6301 atactaatgg atgaaagaag ttttggctat caaggaggaa tgcacatgca tatcgaaaga
     6361 ttaaaaacag gaatgattga agaaaactgt tatttggtct acaacgaaga agcacttttg
     6421 atcattgacc ctggagaaga tgcggaacga atcaaacaag aaatcaaaaa aacaaaccaa
     6481 cagccggtag cgattttgct tacccatact cactacgatc atatcggtgc agtggaacct
     6541 ttacgcgcgt attatcaaat cccagtttat gtcagcccac tagagcaaaa atggctaggt
     6601 gatccgattt tgaatctttc tggactcggt agacatgatg atattgctga tgttattgtc
     6661 tcgcctgcag aatatgaatt tgaaatgaaa acttatactt taggaaacat gtcttttcgc
     6721 gtcgtcccta ccccagggca ttctatagga agcgtcagct ttatttttga tgattttgtc
     6781 gtttctggcg acgccctgtt tagaggaagt atcggtagaa ccgatctgta tacagggaat
     6841 ttagaacaat tacttcatag tattcggacc cagctgtttg tattacctga tgaatttgca
     6901 gtctatccag gacatggcga tgcaacgacg attgaacagg aaaaaaggac aaatcctttt
     6961 ttcaatcgtt aaaacgactt aggaggagaa taaaatgaca gaaactacac tttatatcgt
     7021 acgacacgga aaaacgatgt tcaatacaat tgaacgagta caaggctggt gtgatacacc
     7081 cctcacaaag caaggacaag aaggcattca ttatttaggt cgcgggttaa aaaatgtcga
     7141 cttttcattt gcttattcta gtgacagtgg tcgtgcaatc gaaactgccc gtattattct
     7201 aggagaacat tctaagggaa aagaaattcc ttattttatt gaaaaaagga ttagagaatg
     7261 gtgtttcggg tctcttgaag gtggatatga catggaaatg tggggtgtga tccctcgtgt
     7321 attgaatttt aaaacatatg atgaaatgtt taccacagaa gtttcttttg aacaaattgc
     7381 taatgctgta tacaacttag ataccgctgg gtgggcggaa acttatgaaa cattgcgaga
     7441 ccgtgtatgg acaggatttg aagatatcgc ccatcactgc gaaaaaaatg gtggtggaaa
     7501 tgttttagtc gtatctcatg gtttgacgat cgcctttttg cttaatctga tcgatcctaa
     7561 acagcctgtt cgtgctgggc ttttaaatgg cagcgtaaca aaggtcactt atgcaaacgg
     7621 tcgattttct atccacggca tcaatgatac gtcttatatc gataacggga aaacacatag
     7681 tcgcgactcg tttctataat ggggatattt taatttttac cagagaatca taaaaggcaa
     7741 agtctgaacg agggctttgt cttctttttt ctcttcgtgt acttatctgc tttatttctc
     7801 aagtttttct taatattaaa aaacagattg ggtttctcaa aaaataacgg tatactataa
     7861 gatgtatctt aattgggaag gaaggaattt atgttttttg caaatattat caaagcagtg
     7921 attctcggta ttattgaagg aataacggaa tggctgccca tcagtagtac tggtcatttg
     7981 atcctagcag atgaattcat caaactggat gccagttcac aatttatgtc gatgttcaat
     8041 gtcgttatcc aattaggggc gatcttggct gtcgtcgttc tttattttca caagttaaac
     8101 ccattttctc caagtaaatc aacggtagaa aaaaaagata cgtggacact ttggtttaaa
     8161 gtgatcgttg cttgcatacc agccatcatc attggtttgc ctttggatga ttggttagaa
     8221 gcaaatttcc acaagttctt accagttgcc attgttttga tcgtttacgg tattgccttt
     8281 attattgtcg aaaaacgcaa caaaaacaaa acacctcgtt ggacttctct gaatgacttt
     8341 acgtaccaag cagctcttct tgttgggtta ttccaagtct tggcacttgt tcccggaaca
     8401 tcccgttctg gcgcaacgat cctaggatct atcttgattg gtgcttcgcg ttttgtcgct
     8461 acagagtttt catttttctt agggattcct gtcatgtttg gcgcaagcgg cttgaagatc
     8521 gtcaaatatt tagctgaagg gaattcattc aaaatggaag aaactgttgt tcttcttgta
     8581 ggaacattcg tatcttttgt ggtttccgtc ttagctatca aattcttact aagctatttg
     8641 aagaaaaacg actttaccgc ttttggctgg tatcgtatta tccttggtat cattttgatt
     8701 ggttattggt ttattgcaat gtagaaaaaa ccagaacact tctct
//
LOCUS       DAFTHM010000107         8675 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFTHM010000107 DAFTHM010000000
VERSION     DAFTHM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.107"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..1101
                     /locus_tag="L7C88_002389"
     CDS             <1..1101
                     /locus_tag="L7C88_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBP9559186.1"
                     /translation="KKETIVRFEQYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLS
                     HSIADHVRYKIASLLTEKVSLSFIAKSCQVSLTTVTRTLKEFKSYLPKPSKKILPRVL
                     MVDEFRSHASIEDKMSFICADGETGNLIAVLPTRKLPRLTSYFLGCTNPEEVEFLVTD
                     MNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQALNELRIREMNELRKAGQKSQAEKLKK
                     NWRFLLKNRASINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSAPLKEAYPFFHELV
                     EAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITSAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
     gene            complement(1280..1609)
                     /locus_tag="L7C88_002390"
     CDS             complement(1280..1609)
                     /locus_tag="L7C88_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBP9559187.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(1599..1871)
                     /locus_tag="L7C88_002391"
     CDS             complement(1599..1871)
                     /locus_tag="L7C88_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBP9559188.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2322..3125)
                     /locus_tag="L7C88_002392"
     CDS             complement(2322..3125)
                     /locus_tag="L7C88_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBP9559189.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3103..4227)
                     /locus_tag="L7C88_002393"
     CDS             complement(3103..4227)
                     /locus_tag="L7C88_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9559190.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4243..5058)
                     /locus_tag="L7C88_002394"
     CDS             complement(4243..5058)
                     /locus_tag="L7C88_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBP9559191.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5048..5920)
                     /locus_tag="L7C88_002395"
     CDS             complement(5048..5920)
                     /locus_tag="L7C88_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBP9559192.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6005..7294)
                     /locus_tag="L7C88_002396"
     CDS             complement(6005..7294)
                     /locus_tag="L7C88_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBP9559193.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7522..8166)
                     /locus_tag="L7C88_002397"
                     /pseudo
     CDS             complement(7522..8166)
                     /locus_tag="L7C88_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2691 a         1850 c         1371 g         2763 t
ORIGIN      
        1 aagaaggaaa cgattgtccg ttttgaacaa tacaatcata tgcctttggt tacgcgccta
       61 aaaaagcaac gctatacctg taaaaactgt cgtacccatt ggacggctca aagttatttt
      121 gtccgactca gccattcaat cgcagatcat gttcgatata aaattgcttc tttactgact
      181 gaaaaagtat ctttgtcttt tattgcgaaa agttgtcagg tatctttgac taccgttact
      241 cgtacattga aagagtttaa aagctattta ccaaagcctt ctaagaagat tctccccaga
      301 gtattgatgg ttgatgaatt tcgttcgcac gcttccatag aagataaaat gagctttatt
      361 tgcgcagatg gtgaaacagg aaacttaatt gctgtcttgc ctacgcgtaa attacctcga
      421 ttaacaagct atttcttagg ctgcaccaat ccagaagaag tagaattctt agtcacagac
      481 atgaacgccg cttacttcca gcttaccaaa cgtgttctgc caaatgcgaa agtagtgatt
      541 gatcggtttc atattgtcaa acacatgaat caggcactca atgagttgcg tatccgtgaa
      601 atgaatgagc ttcgtaaagc aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      661 cgctttctgc taaaaaatcg tgcaagcatc aaccattatg agtacaaaac atggaaaagt
      721 ttccgagcac caaaataccc atttctcact gaagcaatga tgattgatcg attgcttgag
      781 ttttctgcgc ctctaaagga ggcgtatccc ttttttcatg aattagtcga agcctttcga
      841 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      901 ggctttcggg agaagcttca aaaccttctg acctatgaag aaggtatcac cagcgcaatg
      961 atctatcctt attccaatgg aaaaattgaa gcgaagaata cccacataaa gacaatgaaa
     1021 cgagtatcct acggatttaa atcattcgag aacatgagaa ttagaatctt tttgatcaat
     1081 caattaatca atgtaagata acaaaaaatc tgaaccagaa tgtggttcat tctgacccgg
     1141 atttgatttt gcacaactca tcagtcctta ttgacaaaga gccaaaaatc tgagccagaa
     1201 tgaggttcat tctgacccag atttgatttt gtacaaccca tcagtcctta ttgacaaaga
     1261 gcccttcttt ttagtattat tataattctt ccatgcgttc ttccagtcgc tgtaaatcgc
     1321 ttggacttaa ttccccaatt tttttccatt tgaccttttt gttgtttttg ggtaattcgt
     1381 ttagagttcc tacgtcaatc caagattctt tttttagtcc tgcctgtttc caatccctta
     1441 tttcaacgta tttcagcttt attttatcgg atttagtatg atattttgaa gtaattgaca
     1501 gaaacgaaat tgtgtccagt ccatttttta gaatatagac aggccggcgt ttaccgccct
     1561 ctgcagctgt gaaagcaacg tagacggttg ctatatcatt agtattcatc ttcattgaac
     1621 cattcttcaa ttttttcgtc agtgtctagt ttttggacag gcaatttttc cgctaatctt
     1681 tgaatattat ggattcgttt acttttttcc gacaattcaa tagaaaatgg gatttttcct
     1741 tgctcaacaa tttgcttata aaaaacggtg acggctgttt tggggctcat gcctagttca
     1801 tcaataatgc tttctgcttc atttttcaat ttttcgtcca tagaaatttg taacttagcc
     1861 attttctcca cctctttctg acaaacacat tatatcacgg aaagagttca aatggaatta
     1921 atacaactac ttttgaactc cttgaaatgc agtgtattta tctaaatata aggaaaggat
     1981 atagtgctaa atggccttga tagatagaaa agtttcaaaa tccgccacag cgataattga
     2041 agcgaacact caacgacaca cagaacagga aaagactcct aaaagaacca aattaactag
     2101 gacgtgtctg aaaactccac aaagatgtgg tatgctctgg taaaaaacga atggcacaac
     2161 cacgaagacc gatatggttc ttggaaaact ttctccaccc tttttgtaat tggagggata
     2221 gtggtttatt gatagcgatt ttccaagttc ttcaagtgga accagacatt gagcaccacg
     2281 gctaaaaagt gaatgaagtc tttattttta atcaataatt tttaatgatt accagtaatt
     2341 ggttttttca tgcgccctat ttctatttga tgtggagtta aataatgctg ataagtaaaa
     2401 atttttccgt caattaaact gccactagtg aatcctgttc tattggtaaa aagagaatag
     2461 tctgggtatt catctacacc aaatgataaa gattcagcca taaactgttt tttaccagca
     2521 aattcagcac tgctaccttg atggatatgt cctacaaaaa tacctaaaat atcactttcg
     2581 gcaatcaatt cagcaaaacc ttccggaact tcagttacaa tagatggatc ttcccacgac
     2641 aatggatgat gaaccaataa aatcgttccc ttttcagcag gtgtacccaa ccactcttgt
     2701 aattgaatca tctgtcctat cgatattttt ccttcgtgct gggtatcttg agcagaatcc
     2761 aaggaaataa ttcgtaaccc attttgattc gtacaatgga tatactctcc cgtttcattg
     2821 ctttcaacac tcattccttc aaagaaaaca ctgcgacgat catgattccc acgacaaaaa
     2881 tagtaaggtg tggttgggaa atattgatcc aacattttcc gtaagacttg ataatcagaa
     2941 atcccccctt catgtactaa atcacctgtt aatagaataa aatcgtacac tgttaacgag
     3001 agttcttgta acaatttttc caatgccaac tgtggatttt taattgttgg aaatagttca
     3061 gcagtaaaca agttagtttg atagttttct ctaaaatgga tatcagagag atgcaaaaag
     3121 cgcatggcta ttccctcttt cttcaataaa ataatcagga tatcctaaat tttcttgcgt
     3181 ctgataatca aaaaaatgca ttctttcagg ttctatgcgg agattgactg catcaccaat
     3241 ctgccaagta ggtttttcat taaggacaat catttctata ccatcgactt taacggtgta
     3301 cgcataactt tgacctaata gctcacgata cttcacttga ccgtgtaaat cgcttgtttc
     3361 ttttgaaaag gttacgtgtt ctggtcttat gcctaaatac aatgagccac taacctgaag
     3421 aagttgtttt tgccaagctg gattcaatgt taaaaattga ctggctacct ttaatgttcc
     3481 ttgatcataa gtaactggca taatattcat gcctggcgaa ccaataaaat ttgcagtaaa
     3541 agtattttta ggtttcgtat aaacattttt cggcgtatca atcatctgaa ttctaccttc
     3601 attcaataaa acaatccggt cagctaacgt catcgcttca atttgatcat gagtgacgta
     3661 gacaaaagtt tgtttataac gttgatgaat ttttaccaat tcttttcgtg catccaatcg
     3721 taaacgcaca tccaaatttg ataacggttc atctaataaa aaataattac tccgtttaac
     3781 caccgcacga gccaatgcta cacgctgccg ttgccctcct gacaaatctt taggaagtcg
     3841 atcttggtat ggcgttaaac ctaacatctt caaagcttct tccaaacggt gctgaatgtc
     3901 agctgtctta attttattcg cccttaatgc aaaaataata ttctccttta cagtcatgtg
     3961 aggatataaa gcataatttt gaaaaaccat tgcgatctct cgttctccac aaggtagctt
     4021 atttgctagt tgtgtaccta aaaaaagctc tccactcgta attttttcca aaccagcaat
     4081 cattctcagc aaagtagatt ttcctgaacc agatggtccc agtaacacaa ttcgttctcc
     4141 agcggccaca gctaaatcaa tttcttttaa aatggtatgt tctccatatt tttttccgat
     4201 atttcttaat tcaagcgttt ctcccatgat ttgtcctcca atttatttaa tacctgcaga
     4261 aacaaaagtc ccgataatat atttttgaaa aattgcatac aagactaacg gtacaaacat
     4321 tgtaattaaa ctaatcgcca ttgctacggt aaaatttgtc ccaccttcag aactaatata
     4381 ggtctgcatc gccaacggca aagtataatt atctactgtc cgtaaaatta ataccggcca
     4441 aacatactca ttccaagagg taataaaaaa ccaaataccg gtagaagtaa tcgcatgtct
     4501 agtaagagga aaaacaattt tactcatgac ggttgtttgt ttgatgttat ccaatgccgc
     4561 cacatctaga aggctcactg gaatttcccg cattgtttgc gtcaataaaa aaatgcccat
     4621 cgcatcagca aattgtggta ttatcacacc ccaagtagta tcaattaaat taagttttgc
     4681 aatcaacaaa taattaggaa tcatcgcaac agtaaaagga atgaacatcg taccaatgat
     4741 gataaagtac cagattttct tccctttgat tcggcaataa gtaaaactat atgccgcaaa
     4801 aaaagctacg cctaacttaa caaccgttat aattgtagca ataaaaaaag tatttctcgt
     4861 aattttgata attggaagat tttcgaacaa atagcaaaaa ttttccaagg taaacggctg
     4921 tggtatcaaa ctagtaatcg tctgataggc atctttcaat ggcttaaaag aattggccat
     4981 aataaacaat aatggataga taataatgat tatgatgaac ataaataaga gatgtggcaa
     5041 ccagcgttta attttcatag taaaccccct tttccacaaa tttaaatatt acccctaaga
     5101 aaacagcaaa tattaataaa gttaaaactg aaattgctga agattctccg actttataca
     5161 tttcaaaagc cttttgataa gcataataga tcacgtttgc actaccatta ttcggtccac
     5221 cacgagtgat gatcttaatc ggagtaaaca catactgcag accttgaaca atggtcatca
     5281 ccaataaata tagtcctgtc gaactactca taggcaacac aattgtaaaa aaaatgcgcc
     5341 agatgggtac acgatccaac ttagctgctt cgatcatctc ttgatcaatt cccacaattg
     5401 ctgcaaaaat gacaatgaaa ttataaccaa aaactttcca agcagtaata cctgcaatca
     5461 cagcaattac ccaaccttgt aaattcatcc acataggcag tcttaaacca aaatttccca
     5521 acaagacagc aattggtccc gataccggat ttaatatcca tgtaaaaacc atccccgcca
     5581 ctaccaaaga aatcacagct ggaataaaaa ataatggttt atacaaattc tgcccttttt
     5641 ctataactat tcctaataaa aaggatgtaa tatatgggaa cacacagctc agcaagacaa
     5701 atagaacggt ataggacaaa gtattcttca acactttatg aaagactgga tcagtcagca
     5761 cctttacata gttggcaaag ccaacaaatt ctttagtggg ggccaccata ttccagtcaa
     5821 aaaaactcaa atagatcgta taaatcaatg gataaaaaac aaacacgccc aacaaaataa
     5881 ttgctggcgc cagatacaaa taacctacat agcgcttcat ttccgacagc ctcctcatcc
     5941 ttatgtcaaa agcagacgac cttgtttttc ctttcttaca ggcgctgtcg tctgcttgct
     6001 ttgcttattt gagtaactca ttaatttcct tttgagtagc tttcatcgtt tcattgacgg
     6061 aattacctga taaaatttta tcccgcatat ccaacaattt ttgttcagct tctaatccag
     6121 catctccagg aaatgaactc caactgacca tcttatccat ctgatcaatt gctggtatca
     6181 tcatctgatt ttcagctaag aaagctttta atccattttg ggcgtctgca acatctttac
     6241 gtggtggtaa ataaccagta ccttctgtcc atttagctaa agattcaaca ctataaagat
     6301 attttaagaa atcccaagtt gcttcctttt tcttatccgt ttgtgatgta acagctaaca
     6361 ttgcgccacc agcaggtagt ttaacttttt tcccttccca acttggtgac tcaactgctt
     6421 tagcagtaaa agtactattt ttttgaatgt tgtccctttg agcaatagtg gtatagacca
     6481 tcgcgacgtt accatcaata aagctttgca caccttgttc ccacgtagtg tgtaatgccg
     6541 tctggtcttt taccatcctt tgatataatt cataagcagc gataccatct ttagaagcaa
     6601 aggtagcttt gccatctttt attacacttg ccccattact ttctaaaatt gcttgttgtg
     6661 cccaattatc agcaggttct tgaatataca cgccatactt tccagttttt tcttttatta
     6721 tcttagaaaa agtttgaact tcttcccaag tttttggacc attttcatcc aagcccgctg
     6781 cttttaatat atcttgattt aaatataaaa ccggattact aatggagtaa ggaataccca
     6841 cttgtttacc atctttttca gacagtgcca tgatattgtc taaaaaatga tctttaaaat
     6901 aatcagcatt atccggatcc acttcttcta ctaaagattg aggattagta tatttgaaat
     6961 tttctgcaaa ataatcttta aaagcccatc ccacttgtac tacgtccggt atttctttgg
     7021 aggcaacaga agcttgtaaa ttttgcatca agcctttata catatcagga ttatattttg
     7081 ctacaacctt cactttgtct tgagattgat tgtatttatc tactaattca ttcactgttt
     7141 ttccacctag ggtatccgca ttaacatgcc aatactctat cgttacacga ccctccgatt
     7201 tttttgttgt cttggtattc ccactaccac aagctgccaa agagatgaca cttaaaacag
     7261 acacaacccc tataacaaga tttttcttta acataacatt aacttcctcc taatttcttt
     7321 atggccattt ttctaatcaa gaaatattat gaactaccaa tgtaaatttc tagttaattt
     7381 tctgtaaata attcgaaatt tgtgcatttc ggggtacagg gtcactggac atatccatca
     7441 agctaagaat aaagccccca tatggtcatg tatcccatct ccaaatctct taactcctct
     7501 gttttgatta taaaatagtt tattctgtgc tcctttcttc cataaatagg cccatgcaca
     7561 acgtgaggtt atattataaa caccacagcg cgcaaggtac tcaatcgttt ctagttcatt
     7621 gactgtccat acagaaaatg tcaatcctag ctgctgcccc acttcacggg ccaacttagt
     7681 taaccatcct tcatgaatat tgacgatttg aacgctttga taggctaatt tctgtaaggt
     7741 atcgatcaaa tctgcttcgg taatatcccc aagttttttc ccttcgaact gattttcaat
     7801 attataaaat atatgctttc cccaaatcgc agcccaagat aattgtacat agccactaag
     7861 aacaatttgt ggccagattt gataggtttg tgccagcgaa aaaacggcca tttccaatcc
     7921 ctcttctttt aaatcacagt taatggtcat ggttgccttc tcattggcca ctgcttgaaa
     7981 cacctgctca agggttaccg aatctgggac aacttcttac ctgtcatggg ctagtattag
     8041 cgtaccatct gtttgctgac gcacatctac ttcaaaacaa agctggcgat ccaaacaaaa
     8101 gcgaagaaat gcccagctat tctcctccgt attgtcacta ccagagtgtg cagtgatcat
     8161 ggtcattttg acccctcctt taattccgtg attttctccc acacgtccac tataccgatg
     8221 aagcgttaat ttcttgttaa tttcttgtaa attccctgcg ttttttcagt aaactagttg
     8281 taaatcttgc atgctccttc ctacgaactc atgaatcgtc gattttgccc ttctagctag
     8341 tttcaccaat taagtagttc tacattcccc gcttttaacc tactacacct ttttttgttt
     8401 tcagctattc cttcttcttg ctgaaagtcc ttgaggttct ttcttacagg ataccatcaa
     8461 ggtgttcaat ggcttattcc cattgaatga ccgagactta ctatcagatt tctgctcgtt
     8521 gaaccaagtc tttgatacag gatttcttcc gtcatcttct cacaaatacc accttgcgtt
     8581 tctctagcga ttggtcgatg tgcaccctcc cagtggactg tcactacccc tttttgctat
     8641 gcctagccca caaaaaaagc tgtcctcaca gacag
//
LOCUS       DAFTHM010000108         8543 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFTHM010000108 DAFTHM010000000
VERSION     DAFTHM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.108"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..278)
                     /locus_tag="L7C88_002398"
     CDS             complement(<1..278)
                     /locus_tag="L7C88_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9559194.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIE"
     gene            420..1538
                     /locus_tag="L7C88_002399"
     CDS             420..1538
                     /locus_tag="L7C88_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBP9559195.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            1666..3042
                     /locus_tag="L7C88_002400"
     CDS             1666..3042
                     /locus_tag="L7C88_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBP9559196.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            3443..5023
                     /locus_tag="L7C88_002401"
     CDS             3443..5023
                     /locus_tag="L7C88_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBP9559197.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            5221..5444
                     /locus_tag="L7C88_002402"
                     /pseudo
     CDS             5221..5444
                     /locus_tag="L7C88_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
     gene            complement(5649..5969)
                     /locus_tag="L7C88_002403"
     CDS             complement(5649..5969)
                     /locus_tag="L7C88_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBP9559198.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(6117..8351)
                     /locus_tag="L7C88_002404"
     CDS             complement(6117..8351)
                     /locus_tag="L7C88_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9559199.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
BASE COUNT         2638 a         1516 c         1686 g         2703 t
ORIGIN      
        1 tcttcaatca atatttttcc taacccttgg tgtctgtatt cagaaagaat cgccatccgc
       61 tgtaatttca tttttccgtt ttctaaaggc aaaagacgta cagttccttg cggttctttt
      121 ttatctgagt acaggacgaa gtggatacaa tgggcttcat ctttgtctat ttctcgagac
      181 aaaggcacac cctgttcgac tacaaaaact tgatgcctga tccgtacagc atctaagtaa
      241 atattgctca ttgtatcttt tgtttgtaca actttcatgg tctagccacc ttcctttcgt
      301 atagtatact ggaaaataaa acaaataaaa agtatggcaa gttttcaaaa ataaaaaaag
      361 aataaaagaa tttttaacga atataatata tactagtaag aaagaaagga ggaaatctat
      421 tgtttgaaaa acttagacag tctaaactaa tgttttggtc gcttgaatta ttgatcatag
      481 ctgcattgat catgatttca tcagaaataa actttatttt cgaaccgatc gggacatttt
      541 tttccacgtt atttgcacct gtactgattg caggctttct ttactattta ttgaatccta
      601 ttgtcaagct gttgatgaaa gcaaaaatca aaagaatatg ggctgtcgca attgtgctgc
      661 tccttttagt tgcagcaatt atttggattt tacttagtgt catcccaagt ctagtacagc
      721 aaatttcctc attggcatct aatatgcctg atttcatcaa acaggtagaa agctggttaa
      781 aagaggtagc cgaattgcct ttgttcaagg aagtagatat caataaatat tttgagcaat
      841 tagacatttc ttacgggaca atcattcagc aattccttag tggagtatcc aatagtttag
      901 gttcgatcgt tggaacgatc gcttcggcaa ccgtagtaat cattacagca ccattcatct
      961 tgttctatat gttgaaagac ggagaaaaac tagtgccaaa catccaacag tttttcccag
     1021 aaaaaagaag aaaccaaatt gtggagttat tggggcaact gaataaaaca ttggctaatt
     1081 acattagcgg acaagcaatc gaatgtttat tcgttggtac cttcacattt ttaggatata
     1141 tggtaattgg tgtggattat gctttcttat ttggggtcat tgcgggattg acaaacctaa
     1201 ttccatattt aggaccttat ctaggactag cacctgcatt tctagtaaca gtcttcaatg
     1261 atccggtaaa agcattactt tgttgtgtgg ttgtgctaat cgtccaacag ttggatggga
     1321 atatcattta tcctaatgta attgggaaat cactgaaaat ccatccatta acgatcatta
     1381 tcgttcttct agtagctgga aatattgccg gattgcttgg tatcttctta ggtgttcctt
     1441 tttacgcaat ctgcaagacg atcatttcct atataatcaa aatcgtcaaa gaagacaagc
     1501 aaaatgaaaa caagaagaaa attgctacga cctcgtaggt agttttagta cacttgtttt
     1561 tattgcaaag aaaattgctt tgtgatacca ttttaacgtg gctatagtgc cacgtttttt
     1621 tctatcgtaa actaaaaatt aattttataa ggagagaatg cgattatgaa tgctgaccct
     1681 gagagtcagt cgctgttagc gcagatttta ttattgatcg ttttgacatt gatcaatgct
     1741 tttttagcag cttccgaaat tgctgttgtt tcgatcaata agaatcgaat cgagcaaaaa
     1801 gctgatgaag gagatgtgaa atctcaaaag cttttaaaaa tattgcagaa tccaaataat
     1861 ttcctatcga caatccaagt aggaatcact ttggtcaaca ttttgtctgg tgcttcacta
     1921 gctaatactt tatcggaacg gttagctccg gtattaggtg gcggcacagc ggcaaaaaat
     1981 attgcaaata tcattgtgct ggctattttg acctatgtat cgattgtttt tggagaattg
     2041 taccctaaac gtattgcttt aaataaatca gaagaagtcg caaagttcac ttcagggctg
     2101 atacgcttga ttggtgtagt agctaagccc ttcgtctggc tgctttctgc ttccacaagt
     2161 ttattggcgc gtatcacgcc gatgactttt gatgatgaag attcaaaaat gaccagagat
     2221 gaaatgcgtt atatgcttga aaacgaaggc gtattgaata atgaagaatt agaaatgctc
     2281 caaggggttt tttctcttga tacgaaagtt gcccgagaag tcatggtccc acgaacggat
     2341 gcatttatga ttgatatcaa cgacactgtg gaagaaaatg tgaatgaagt tttatccgaa
     2401 aactattcaa gaatccctgt ttataacgaa gacaaagata aagtagtcgg aatccttcat
     2461 acaaagaatt tactaaaagc tgcccataaa ttcggctttg ataatttaga tatcaagaaa
     2521 atcatgcagg agcctttatt cgttcctgaa acggtcttta ttgatgatct gttatatgaa
     2581 atgaaaaaga cgcagaatca gatggctatt ttattagatg aatatggcgg cgtcgttggg
     2641 ttagcaacac tagaagacct tttagaagaa atcgtcggag aaatcgatga tgaatcagat
     2701 gaagttgaga atctttatga aaaaatcgat gaacacgaat atatcatcca aggacgtatg
     2761 ctgattgatg agttcaatga agcttttgac agtgatctgc atatgagtga tgtagatacg
     2821 atggctggtt atttgattac agcattaggc atgattccgg atgaaggcga aaagttatcg
     2881 tttgatgtcg ataatattac gctggtttct gaagaaatgg aaggttctcg aatccttaaa
     2941 atccgtgtca tttttcatga tccggaagaa acagaagcgg aacctgaaga agaacgaaga
     3001 tacttcagaa aagaattcga agatgacgag ccaagaagat aattggaaac ttggttatga
     3061 aagacgtgtt gcttgaataa acaagcaaca cgtcttttct tttagtcagc tgacaaaaaa
     3121 atatttgact cttatggttt ggtggctttt tcattcgctg aatccatgct atactgattc
     3181 agttgtagta gttgacaaag gttgtgaaaa agctatcctg cattaagtaa taagagcagc
     3241 caagcaaaaa cagcttttcg tatttttggc ttgggtgggc ttattgctga taggctgtct
     3301 ctagaacgcc gtttactcgg aaaaagagac tgctacacgg cttttgtcac agccctatat
     3361 gaaattgtct ttctttaaga gatcggacaa tctgtgccta gagaaaatat aaataattga
     3421 atggaagaaa tggagttagg ttatgaataa tccaaaatta aagcaacaag tggacaatcg
     3481 cagaactttt gcgatcattt cccatccgga tgctgggaaa acaacgatta cagaacaatt
     3541 actattgttt ggtggggcta tccgtcaagc cgggaccgta aaaggcaaaa aaacaggtaa
     3601 ttttgccaaa tcagactgga tggaaatcga gaaacaacgt gggatttctg ttactagttc
     3661 tgttatgcag tttgattatc aagggaaacg agtaaatatc ttggatacac caggacatga
     3721 agatttttct gaagatactt atcgtacttt gatggccgtg gatagtgcgg tcatggtaat
     3781 cgatagtgca aaagggatcg aagcacagac aaagaaatta ttccaagttg taaaaaaacg
     3841 tggcatcccg atatttactt ttatcaacaa actagatcgt gatggtcgtg aaccattgga
     3901 attgttagaa gaattagaag agctattaga tatcgaatct tatccgatga attggccaat
     3961 cggtatgggt aaagggctag aaggtcttta tgatatctac cataatcgtg tagagtttta
     4021 tcgtccggaa aattatcagg atgaacgatt agtagaattg gatgaagatg gactgcttcc
     4081 cgaaaatcat cctctaactg aaaattcctt atatgaacaa gtcttagaag aagtagaact
     4141 aatcaaagag gctggagatg catttaatca agaaaaaatt gctcgtggcg atcagacacc
     4201 agtatttttt ggttctgcat tgactaactt cggtgtacag acttttttag agactttcgt
     4261 tgaattggca ccagctcctt atggacacaa aacacaagat gatcagatgg taagtcctta
     4321 tgaggaagaa ttttcaggtt tcgtattcaa gatccaagca aatatgaatc cagcccatcg
     4381 tgaccgaatc gcttttgtcc gaatctgttc tggaacattc gaacgaggaa tggatgtctg
     4441 gttggaacgt acaaataaaa aactgaaatt aagcaatgtc acacaattta tggcagattc
     4501 gagagaaaac gtcgaaaaag cagtagcagg cgatatcatc ggtgtatatg atacaggcaa
     4561 ttatcagatt ggggatacat tgttcgaagg aaaactaaaa gttgcttatg aagaactccc
     4621 ttcatttact ccagagctgt ttatgaaagt gactgcaaaa aatgtcatga aacaaaaatc
     4681 cttccacaaa ggaatctatc aattagttca agaaggagcg attcagcttt ataaaacata
     4741 tctaacggaa gaatatatca ttggagctgt tggtcagcta caattcgaag tattccaata
     4801 tcgtatgtta aatgagtata acgccgaagt aatcatgtct ccaatgggac acaaaatcgc
     4861 tcgctggatc gatccagaag atttggatga gaagatgagt tcaagtcgca atatcttggc
     4921 tcgtgaccgt ttcgaccaac cgttgttctt attcgagaac caatttgcag aacgctggtt
     4981 tgcggataaa tatcccaatg taaaattaaa aagtttgatg taaagaagtc ttgacacaag
     5041 ctgccctgca tcaagtaata agaatagcca aacaaaaaca gcctctcata ttttgtttag
     5101 agccgtgacg gattttccgt gacggctctt tttactatat taaaatcata gaaatgtcta
     5161 atcaaaaaaa tataaaaatt attttgcgta catatgatta aagaaaggag agtgtgacac
     5221 atggaaacag aatggcaaag acgtgaaaga aaaaaacaga aaaagaagag atgttacgat
     5281 tatgtcgatt attagatgta aaagactggg acaaaaacga gcaaattgca caaaaagtac
     5341 gatcaatcat ccataaagag gaaaaagtta aaaataaaga cacgcgtaga actgaaaatg
     5401 aaaagagaaa agtacaaaag aaaagagaaa aatcaaaaag ctagaaagaa aaagaggctg
     5461 agacagaagc gtttaactcc aagaaataag ctggaattca caaaaatttg aaaagcaatt
     5521 ttcgtgaatt tcagcttatt tccgaaggag ttgcttctgc tttcgccgtt tatacgtgtt
     5581 tagagcgtga gacaaaagtg ttctttactt ttgtcccacg ctctttaatt attatgttca
     5641 aaatttgttt acacggctaa tgtagcgcct aattcatgtt ttggaatcga gatttcaaca
     5701 aggcctgcca attcgattac tttgatttca tcctcgtggt aaacggcgtc tttgatttta
     5761 tctaagaaat aatttttagc atcttcgatt tctttcggct ggattttacg tttgtcattg
     5821 atcagcagaa tttcattatg ttcaggggct tcagtgtaga caatagtggt atttccggct
     5881 gtgtagacct tgactagatg ggcatcagtg ttttcaagct ggtttaatac aagacgggaa
     5941 tggctgtttg ttacatttac caatttcatg gcgctcacct cttttatgta tttttaattg
     6001 cttgtttctc ttattataat ttctttttta taaaatgaac agtattttga cttttctgaa
     6061 aaaagaatga gacggcattt ctcaaagaaa taccgtctca cgctataaaa ctggatttat
     6121 tcagccgttt cttcggctga ttctttagcc aaacgttctg gtttagaagt aacgatgatt
     6181 tttccatctt tatccagttt tgctttcaac tcatggatag aagggtgatc aagataaaat
     6241 tcagcgatac catcttcgat ttgttcttgg atcgtgcgtc gaagaggacg agcacccata
     6301 gatggatcat agcctaagtc aactaatttt tctttgacat tcgtaggaac ttcgatgtga
     6361 agttgctgtg ctgccagcat ttggttgaca tcgtctagca ttagtgtgac gattgtcatc
     6421 aagttttctt ttgataatgc actgaattcg atgatcccgt caaaacggtt cagaaattct
     6481 ggtgtaaagt agttgtttaa ttggttcaat acagaacgag taacaccttc gcgtgccgca
     6541 ccaaaaccaa cgtttgcttc tactttacca gttccggcat tacttgtcat aatgatgatc
     6601 gtatctttaa agctgaccgt tcttccttgt gcatctgtca atcgaccatc atctaagatt
     6661 tgcaagaaca tatgcaaaac atctggatga gctttttcta cttcatctaa caagacaaga
     6721 ctgtaaggat ttctccgtac tttttctgtt aattgaccag cttcttcgta tccgacataa
     6781 cctggaggag aaccaatcaa tttagagaca ctatgttttt ccatatattc agacatatcg
     6841 aaacgaatca ttgaatcttg tgaaccgaat agttcgtagg caagttgttt cgcaagctct
     6901 gttttaccta caccagttgg tccaacaaat aagaaggagc cgattggacg attctgtttg
     6961 tttaatccaa cacggtttcg gcgaatcgct ttcgctactc gatctacagc gttatcttgt
     7021 ccgatgacat gagctttcaa gtcatctgct aagtttttca gttgtgtctg ttctttttct
     7081 tttaattcac ccactggaat acctgtccgt tgttcaacga ttttttccat atctttttcg
     7141 gtaatcacag gtgtttcctc ttcagtgagc tgacgttctt tcattttttg aagtttattg
     7201 atctgatcgc gataataagc tgctttttcg aaatcttctt ctcgagaagc taaaactttt
     7261 tgttcttctg cttcttgcag ttttttctcg attgttttag gatcaacgat ttggatcgtc
     7321 aagtttttct tagaacctgt ttcatctagc aaatcgatgg ctttatccgg caagaagcga
     7381 tcttggacgt aacgattgga taaagttgcg gctgcttcga tggcctcatc agtatatttt
     7441 acatgatgat agtcttcata acgtttttgc aaacctttca aaatactgat cgtttcttcg
     7501 acagttggtt catctacccg tacaggttgc atacgacgtt ctaaagcagc gtctttttcg
     7561 atgatgcggt actcatttaa ggtagtagca ccaaccattt gcaattctcc tcgagctaaa
     7621 gctggtttta aaatattacc agcatccata tttccatcac cagcagaacc agcaccgacg
     7681 atttcgtgaa cttcatctat gaataggatc acattttctg cttgacggat ctcttcaatc
     7741 aatttttgca tacgttcttc aaattgtcct cgtataccag taccttggac taaagatacg
     7801 acatctaaac gaatgacttc tttgtccatt aatttttgcg gtacatcacc atctacgatt
     7861 ttttgtgcta aaccttcaac aactgctgtt ttaccaacac ctggttctcc aatcaagaca
     7921 ggattgttct tggttcggcg atttaaaatt tcaatgactc gtttgatttc gtcatcgcgt
     7981 ccgatcacag gatcgatatc accttgtcgt gcttgttctg tgatattgat tccgtattct
     8041 cccaataaac cttctgtatt gccttgaggt ggctgaccac cattgaagtt gttgtttccg
     8101 ccaaattgtg ttggtggtgt ttgctcataa tttccttgct gttgcatttg gcgagacatg
     8161 gaacggaaaa gatcgtccaa actgccaaat ccaaatggat cattttgggc catattagtc
     8221 agacctccat tttgttgatt tttgattttt tgataacagc tctgacagta atcgagttgt
     8281 gtccgctgac cattgacagt ggcatacaag tgaatcgttg cctcattctt gccgcagttt
     8341 tgacaaagca tgaatcattc acgtcctttc acaaaaatgg gtacatccat attttacatc
     8401 tcgtttttca tgaggtaaaa gaataacccc tagtttttta agagatttat gaggtagaaa
     8461 aggtgaaatc tctattgacc attcctgacc tttgactctt attatactaa aaataaaaag
     8521 ggaagcaagt aattcgtttc ata
//
LOCUS       DAFTHM010000109         8493 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFTHM010000109 DAFTHM010000000
VERSION     DAFTHM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.109"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..173)
                     /locus_tag="L7C88_002405"
     CDS             complement(<1..173)
                     /locus_tag="L7C88_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9559200.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="L7C88_002406"
     CDS             complement(593..1714)
                     /locus_tag="L7C88_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBP9559201.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="L7C88_002407"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="L7C88_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBP9559202.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="L7C88_002408"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="L7C88_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBP9559203.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="L7C88_002409"
     CDS             complement(4304..5215)
                     /locus_tag="L7C88_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBP9559204.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="L7C88_002410"
     CDS             complement(5232..6239)
                     /locus_tag="L7C88_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBP9559205.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="L7C88_002411"
     CDS             complement(6236..8365)
                     /locus_tag="L7C88_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBP9559206.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8493)
                     /locus_tag="L7C88_002412"
     CDS             complement(8370..>8493)
                     /locus_tag="L7C88_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBP9559207.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2680 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg ttt
//
LOCUS       DAFTHM010000110         7926 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFTHM010000110 DAFTHM010000000
VERSION     DAFTHM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.110"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..199)
                     /locus_tag="L7C88_002413"
     CDS             complement(<1..199)
                     /locus_tag="L7C88_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559208.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
     gene            complement(362..1996)
                     /locus_tag="L7C88_002414"
     CDS             complement(362..1996)
                     /locus_tag="L7C88_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBP9559209.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTNLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            complement(2000..3373)
                     /locus_tag="L7C88_002415"
     CDS             complement(2000..3373)
                     /locus_tag="L7C88_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBP9559210.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            complement(3389..3628)
                     /locus_tag="L7C88_002416"
     CDS             complement(3389..3628)
                     /locus_tag="L7C88_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559211.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            complement(3810..6485)
                     /locus_tag="L7C88_002417"
     CDS             complement(3810..6485)
                     /locus_tag="L7C88_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBP9559212.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            complement(6668..7591)
                     /locus_tag="L7C88_002418"
     CDS             complement(6668..7591)
                     /locus_tag="L7C88_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559213.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
BASE COUNT         2328 a         1560 c         1198 g         2840 t
ORIGIN      
        1 tataataaac atttccttga ggtttccttt taatcccctt cggaaaatca ccttttgtaa
       61 aatcgctctt aaggaaatca tctaaattac cagttctggt ctttttacct ccagtattcc
      121 ctgatttttt aggtggtaca tgttctttag taagttcagt gtatttttca cataaaatac
      181 acttacccat ctttttcata tctatcccca ctctttttaa ttcttatata caattatatt
      241 tcaaatattc attaataaat atccctattt atgataagga cctccctaac tacttctcta
      301 acgatttcaa atcgctagag aagcgttagc gcccctctaa cgttgtttga tataacctag
      361 actagatcgt taacgtaaag ggtgttttta acacaaaaat agccgtatcc tttgttttgg
      421 atacggctat ttgatattgc tcattcaatt gttgtaccac ggcatgcgtg aatttcatcg
      481 taatttccaa catctcctta tggttaggat caaaggttat tttctctata aaggtacgat
      541 acaaggcttt gatttgcttc ttctcactct gggcaagaaa acgatccaaa ttagtcaata
      601 tccgttggac atctttgact tgaatcggct ctccttgttg aaagatccct aagatttcat
      661 tttctcgaat gtgcaactgt cgtcgttttt cagtcaattc gtctaagcgg tcttttaaca
      721 tcggaaacaa ttcaggacta tcttccaaag cagcttccca tttttcaatt ttagtcttca
      781 attcttcctt tcgttccagt aacaccacga gttcttgttc caatggttgg ctttgtcgca
      841 ctatttcttc atttaacgct gccaccaatc ggggaagaac ttctggtagc tgaacgatct
      901 cctttaatcg gtcggcgaca aatgtttccg cttgttcggc acgaatcgaa ttggcatgac
      961 acacacttgc tcctttattc cgaaagactg aacaagaata atatcgaatc cgtttctttg
     1021 tgccatcctt tagggtattt gtgacattac tcgctgccat cggtgcgcca cattctggac
     1081 aacgtaacaa gcctgtcaat acattttcac ctgtatggtt ccatttgggt tgttttcctt
     1141 ctaaagcaag gcgttcttgt actttttgat aatcttcttc cgaaataatc ggttcatggg
     1201 ttcctttcac taaaatcggt ctcggattct tccccttccg tcgtttggtt tcccaattga
     1261 tgtagcgcgc atattctaaa taccctgcat aaattttatt gcgtaagata tctttgactg
     1321 ccgtggtaga aaaagcattc tttttgactg tttgatatcc ttgacgattc aaaaaattgg
     1381 caatcgctcg ataccctgct ccgcctaaat attttgcata gatcagacga acaattttcg
     1441 cctcttctgg ttcaatgacc aattgttttt gaccattcgt gtcaatacca ctgacatagc
     1501 ctaaacgtcg gcctcctgca taacgctttt tatctttcac taagctttgc attgacattt
     1561 gaacattctc cgcaatttgg ttgcgttcaa attcaccgaa actcccaagg agttgtaaca
     1621 tcaatttacc tgtcgaagtg gtcacgtcaa attgttccga gatcgaatgt aatcctacgt
     1681 catatcgcaa taattcctcg actgtttgta agacatctaa catattgcgt ccgagacggg
     1741 tcaatttcca aatcactagt agatcaaaac gatggttccg agcatcgttc atcattcgtt
     1801 gataggcgaa ccgatttttt gtggatttcc cactgattcc ttcatcggca taaacttcta
     1861 ccacttcata gcccatccgt tcggcaaact gtcgtccatt ttgttcttgt gcttgaatac
     1921 tatgtccttc taaagcttgt tcttgtgtac tcacgcgaat atacaatgcg actcgtttgg
     1981 tttgtatcat ttccatagat cattcgttcc tttctaaaat attttgtgtc agttgtcgga
     2041 agtaaatccc acaaactgtt ttatcctttg ttacctcaat ccgacaaaca tagtcacata
     2101 ataattgtcg actagagagg tcttttagtt gaagccattc tttcactttt gcttcacact
     2161 gttggagtga aagaaacgaa gaagtagaca tcggcttttg aagagcttgc agttgttgct
     2221 tgagttcttc cagtgaacaa ttgccctctt caaatgcctt aatccattgt gcttcttgtt
     2281 tcttttgttg gattactttg cgtttttcat cttttcgctt ttcggctaat tgttgcgtta
     2341 attgggcaat caaggcttga tagacgcctt cgtattgaaa aaaagcctgt atcttttcca
     2401 atacttctga ctcaaccctt tctgcccgaa gaaaaattcc ttggcagctt cggtcggtac
     2461 aatgataata atgaagcgtc ttcgtcttct ttgtattcca ttgatacttc gaactcagat
     2521 gacgaccaca gaagggacac cgaatttttt gacgtaataa gtacagatac gtatcttttt
     2581 tagctgtaca ccttgattgg cgaatctctt gggcttgtaa aaaggttgct ttcgagagaa
     2641 tcggttcaaa ggttcctaga tacttcccca aagatcctcc tttgatttcg ccatagtaca
     2701 atggattttt taggatacta taaatatgat agggctgaaa aggacgttcg cggaagaaaa
     2761 gcttttgttg cgtcaatcgt tgacaaagct ttttgtagcc atattttttg gtcaaataaa
     2821 gttgaaaaat atagcgaaca atccttgctt cgtgtacttc ttgttggatt ttcccattca
     2881 ctaaacgata cccatatggt accgcagaag acaaatattg ccgttgttgc tttttatagg
     2941 aaagtccggc acgaacattc tcaataatga cgtttcgttg ttgttctgca aaagtgaaca
     3001 ataattgcac aaatagttta ttcgttgacg cgtgtgagaa agaagcagga agaggttcag
     3061 aaatcgaata cacttgaacc tgatgttgtt ggcacaactc aataaattct aaggctattt
     3121 tggcttgacg tgccaatcga tcataacgcc aaacatagat caccccctct tcttctgacg
     3181 cacaaaccca agctctaagc tgtcgaaaag ctggacgctc cgctttttcc cctgattctc
     3241 ctttgtctga aaatcgttgg ggaatttgtt catatttctc taaaacatac tctttcactg
     3301 catcatattg agcgtcatta ctaattttcg cttcttcata aacagacgtt cgatcataac
     3361 aagccacacg catgcttgat tcccctctct atgaatgaac taaataccat tttttcacga
     3421 ctcttctatt gaacgaacgt tgcacaaagt gattttctaa atatccttcg ttcttcaacg
     3481 cttgaagagt acccccgata gatccagcag atacccctct tatttcgaaa tccaagtaaa
     3541 ttggttttgt aaaaaaggct tgatttgaaa aatgttcttg aatatacaga agaacctctg
     3601 cttttagtgt cattttattt ttagtcatta gaattttcct ttctttcatg tttgattgaa
     3661 tgaagtaaat gaagcataga tcaagcttca tttacttccg tttgggtttg ctcgctatca
     3721 tacagataag taatcagttg ttttgctaaa tcaataagaa atatttccat aacatggtgc
     3781 ctcactttca tactttggtt tattctaaat tacaatcgaa aatacgattt gagtgaagaa
     3841 ggtaatagaa tctcgtatgt tggaagaact tgacgattca tgtgaatacg tttcgttctt
     3901 ctcccttttt ctgcacacat attacccgaa tcaagcaatt gcctaaaaag ataggttaga
     3961 tcctttactt gaaattctcg ccttaacaag tcctcaaacg ggataggaaa aatatttacc
     4021 ttaatatccc catttttttg aattgatact tttccccaaa tcgtactggg cgtatgtttg
     4081 ttgtcactgt ttgttaaaaa tttatggcta ttcatcacca acaatgtttt cactcggtca
     4141 aataccgttt gctcacttcc taaactagta tctacaatta actgttcgta cgaattaata
     4201 agcaccgtct gtatatgctc taatcgtaaa ggatagccca gtatatcttg aattaggagg
     4261 gctccactat aaatcaaagc tagattatta ccaatgcgtt gcttcaaaga atgttcaggt
     4321 aaaacagccc atagtttttt ttgagcttcg acaaaagttg cttcaatttt tgtaatccct
     4381 tgttcaaaga gtttcaaaag aaataacttt ataccccaac caaaagtatt agaagaaaga
     4441 cttttaactt tctctgcgtg attcgcatcc tttgtaaact tgatatcaga aaattcgata
     4501 tatcgaactt tcaaaccagt taatttctca ttgaaataat tttccaaacg ctcttcagaa
     4561 gaggtaaggg tcaaaacaga aaaagtctct tgtggcataa gctgacaatt agaatctaat
     4621 cttagccttt cttctcctga agctaattga tagatcaacg agctaaagtt attttgagtt
     4681 gctgctccta actcatctag tattagtgga acacctccct gattgtttga tgctagcttt
     4741 ataatggctt tattggtagc attcatattt ctaagaaccg tagttggatt tccaaataaa
     4801 gaggcaataa agtgtaacgt agtggtttta cccgttgtgc tcttgccctg taggttaatt
     4861 agtaaactca aaaaagtatt agccttcgta acgtttaaat agcctaacac aatagaagca
     4921 ataccaatcg accaagcaag ttctaagttc gttcctaaaa catacttatg aaccaatgcg
     4981 tcaaattccg cttctgtacc attagttgtt aattggtagc atgagttttt agttaataca
     5041 gaaggaattt cacgtccaaa agaatcttgt aactgaaaaa tcattgcttc attttctttt
     5101 ttccagccaa gagattcatg ttcaaaaaag attggagcat tctcccgttg aatctgtaaa
     5161 aagtcaacga cttcagcttc tcttctagct ttaatgatta agccatgttt tgctaattgt
     5221 ttaaaattat tagtttgtaa acatccacct tctatttcta tttcatccca acaatgatcg
     5281 acataatagg caagaacaag tgtaatgact ttttgttcga tatttttgcg tatttgctta
     5341 ataaacatcg gacaagcaac tttttcttct tgaccttctt tcaccaaaaa tactccttct
     5401 tgattcagtt taaactggtc aaaataatat tcttgattgg attctaatga ttctacagaa
     5461 ggatttacag gttttggcaa cggatatttt tttacaaagt cttgaatatc tttattttta
     5521 tccgaagcat gcagacaatg aaatcgaatc ttattatcag ccgtaacaga caaacaagaa
     5581 ccattagaat tattcgtgtg ttttcttaat ggacattcgt caaatataag taaggtaact
     5641 cctttatgat cgccctcttt tatggtataa gttaattcag gatagtgagc taaccattgt
     5701 ttatagtctg cttgaataaa aggtaacact tctctaaaag atggatggct ttttactcta
     5761 gaggttgaca tcatggaatt ttcttcaact atctgttcaa gaattttaaa acaattactt
     5821 ctatctatgt tatcgggaat agaaaggaaa ctagataaac gatgcggacg ctcttttgtg
     5881 gactttcctt tgaccgctgg tgtaccaact aatttgcata atcttgaagg attataaaca
     5941 gaagtatcaa tatcaacttc atcttctact ccaaatcttc ggtgaagtaa ttgaagaaaa
     6001 ttctgaatag taagaatcgt ctcgtgatta tttggttgtt catttatggg aagaaaaata
     6061 tggtagccat tcccactatc aacttttaca aatgattcta ttctcttttc tttcaaataa
     6121 cgttctactt gttccataac attttctgcc tttttctttt cgctatctgt tgcacttccc
     6181 tctttccttt tagggtcaat atcaataaat acaaaccgaa ttttttcaat atcattgtct
     6241 ctcacagaat gctttttttg tgtaatcacc tcttgtttaa taggattata agttatgttt
     6301 actgtacctt cagacaattt ctgtttttct aaatagttaa taattgcttg agaatctgca
     6361 gtagaaaaaa tatgagaaac ggttttcttg tttaatgtag aaaaagttct caaattaaca
     6421 taagaaatcc ccagtgtatt taacagttgt aaatgcttct gaattgaagt gtgattcatt
     6481 ttcattaatt accactcact ttctaaaaaa tttttatttg tatgactaca ttacctccaa
     6541 cctctcataa tttcatgatc ttcagttcta caaaaatata tcccactcaa aatcttgaca
     6601 aaagaaaaaa gttgtgattt tggaaatcac aacttttttc ttttacgata aatcaatcct
     6661 tattaaatta tttaggaaaa tattgttcaa ttatttcttt atatattttc tcatagtatg
     6721 tttctgtcca tcctaatgtt cctataaaat caagtcctct acattttaaa ggttcactta
     6781 aactattaat atagttaata atgttgtcta tccttttctc tttatcttca ccttcaatct
     6841 ggggagcata tagtccaatt tcctcccaat aatatgaatc tctttcaatt cccatgatgg
     6901 tagctttggc taatttcaaa tcaaataacg attttagaat tcttagtgtc tcaataaagt
     6961 cttctctctt caactcttta atccattgtg aattttctgg attatctaaa atttcaagtt
     7021 catcttcatt ataagtatat ttcaaatttg acttgcttaa ctcatagata aatgaagttt
     7081 cttgactcat aattctttta agtacttgac tataagtttc gtttgacttt gcccatttcg
     7141 ctaattctac cactgtattc actaataaat cgaaataatg atgttctcgt tcaatagtct
     7201 cagcattttg aaaatgaaaa tcacctttat aaactccatt cttttccact gttttattaa
     7261 tattttttaa aaaccagaat gagtttgcaa atttagtcgt actttttcga ttaactaagt
     7321 taataactct tccatgtaat aataagacaa aaatacataa atttttagct tccttattat
     7381 tagatactaa ttgatcaatc atagggagcc attttttgat tttcactaat tgattgctca
     7441 taaatctttc actggacttt tgttcaatct taaattgcaa aacttctaac tcataattcc
     7501 catcttctga tttatttttg ggaacaacta tcaaactttt ataaagttta tccacatcaa
     7561 aatttatctt ttttgcataa tttgtagcca ttaatacatc tccttattca taataaattt
     7621 catatgacgc tcctctcaaa atttaccggt agactagaaa aaagaataaa agatacgtca
     7681 attcacactt tattcttaaa aaaaaactgg tctctctacc ggtaatatcg attgagtccg
     7741 cctttatcga ctttatcctt tttttatatt aaattttttc accggtagac agggagagaa
     7801 agaataaact aaaaagccct taattcttaa tgttttcacc tccttaccgt tcctaccgct
     7861 aaaatttaat ataactaaat tctataacat tagaagaaat tttaaatacc tttgataaaa
     7921 aatatt
//
LOCUS       DAFTHM010000111         7910 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFTHM010000111 DAFTHM010000000
VERSION     DAFTHM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.111"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..518)
                     /locus_tag="L7C88_002419"
     CDS             complement(<1..518)
                     /locus_tag="L7C88_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBP9559214.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRK"
     gene            complement(617..967)
                     /locus_tag="L7C88_002420"
     CDS             complement(617..967)
                     /locus_tag="L7C88_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBP9559215.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(1124..2653)
                     /gene="ahpF"
                     /locus_tag="L7C88_002421"
     CDS             complement(1124..2653)
                     /gene="ahpF"
                     /locus_tag="L7C88_002421"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBP9559216.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(2663..3226)
                     /gene="ahpC"
                     /locus_tag="L7C88_002422"
     CDS             complement(2663..3226)
                     /gene="ahpC"
                     /locus_tag="L7C88_002422"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBP9559217.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(3370..4033)
                     /locus_tag="L7C88_002423"
                     /pseudo
     CDS             complement(3370..4033)
                     /locus_tag="L7C88_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            4217..5863
                     /locus_tag="L7C88_002424"
     CDS             4217..5863
                     /locus_tag="L7C88_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBP9559218.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            5854..6936
                     /gene="uxuA"
                     /locus_tag="L7C88_002425"
     CDS             5854..6936
                     /gene="uxuA"
                     /locus_tag="L7C88_002425"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBP9559219.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(7044..>7910)
                     /locus_tag="L7C88_002426"
     CDS             complement(7044..>7910)
                     /locus_tag="L7C88_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HBP9559220.1"
                     /translation="PATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVN
                     ILARLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYS
                     LAFARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPV
                     ILEKENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKI
                     QNDFMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEAL
                     MDQSKKENQVTS"
BASE COUNT         2510 a         1471 c         1458 g         2471 t
ORIGIN      
        1 atttttctta ttctgatgaa attgataatc tcctggatgc ccatgaaaat caaaataaag
       61 ccgaatattt ggaatagaag catcaaactt ttgaatggat tgaacaataa gacgaatccg
      121 ccaatcaaca acagaatact actataaaca ctccaacttt tagcttttgt attcatgctg
      181 aagaacaact ggaacaagct gttgatgata acagctaatc caagaagaat cggcaggata
      241 gaaacgattg caggtgcaaa agcatagacg atcagagcta agatcaggaa aaaaagacca
      301 ctgaacagac cgatactcca agaacctgtt ttccttttaa aacggtaagc ctcaaaaaga
      361 ttcaacaacc caagcaaaac aagataggcg gtgatcagat aaccgataaa atgaaaaaca
      421 gcagaagggt ttagcacaat cgcaatccca gaaataatat aaacagcagc tcttaataag
      481 gcgtattttt gaatattttg tttaatcgtc tcaaacatat aagaaaacct cctttgactt
      541 attttaacgt gaactagtca ttttaccaaa ttaaatgtta caaaatgagc gaaggagaag
      601 aatatctctg gaaaaatcaa cttctgagga tcttttccat ttttttgcct tttgctagct
      661 catcgatcat tttatctaaa taacgaattt ctttcatcaa gttatcctcg atgtcttcta
      721 ctcgtacacc acaaacaaca cctgtaatca aggaacgtga aggattgggg acaggggctt
      781 ccgcaaaaaa ttgttcgaaa gtcacttgtt tttgtagttg atattctagt tctgtttggg
      841 aataacccgt cagccaacaa atgatttcat ctacttcctc ttttatacga tcttttctct
      901 ccgcttttgc tacatacata ggataaacgc ttgcaaaact tgtcgtaaaa atacgatttt
      961 gcgccataat cagtcacctt tctttttttc aaattattta ctacttatag tatataagaa
     1021 aaagagaaga aaaagcgatt attcaaaaaa acaaaaagga ttgtgacaaa attcttgtca
     1081 ccatcctttt ttccgctctc tgacttttta caatcttcat agctcaagtg cgcatcagat
     1141 aatcgaatgc tcctaaagct gcagtagctc ctgaacccat tgaaacaatg atttgtttgt
     1201 atggactatc tgtacaatca ccagctgcga aaacgccggg gatattcgtt gcgccatttt
     1261 tctcggtcac tatttcattt cttggattca tttcgatcgt tccatctagc caatccgtat
     1321 tagggagtaa gccgactaga atgaatactc ctgaaacagc tagtgtatgc atctccatcg
     1381 tacggcgatc gatataggag agagattcta cctgattcgt accgctgatt tctttcgtcg
     1441 ctgcatgttt gataacagtg acattcgcaa gagagactag tttatcctgt aagatttgat
     1501 ctgcttttaa ttctggtaag aattctagaa catatacatg ttttgctaac ccagccaaat
     1561 cgattgctgc ttcaacacca gaattaccac caccgataac agcaatctct tttcctttaa
     1621 ataaagggcc gtcacagtgt gggcaataag caattccttt atttttaaac tctttttcgc
     1681 ctggtacatt gatagaacgc cagtgcgcac ctgtcgcgat gatggcggtt tttgctttaa
     1741 gtgatatacc gttagctaag ccaatattaa taaaatgttg ctctttattt aaggaaacgg
     1801 cctgttgatt catcataatg tcgatagggt aactacgcac atgactttct acttgctgca
     1861 tcaattttgg accttctgtg taagaggtac caatcatatt ttcaatccct agtgtttcaa
     1921 cgacttgtcc gccgaaagaa tcagcgacaa gtcctgtacg gattccttta cgtgctgcat
     1981 agatagctgc actactagct gctggtccac cgccaattac taatacatca taaggttctt
     2041 tttcaaacaa ctcttcttca atcaaagggc cagtgatttt ttcaacaatt tgttcgatcg
     2101 tcatgcgtcc gctactaaat tcttctccat ttaaaaacac agttggcact gccatgattt
     2161 ttttatcatc gatttctttt tggaacatcc caccttcaat catcgtatga gtaatatttg
     2221 gatttaatac agctaatata ttcaatgcct gtacaacgtc ggggcaatta tgacaagtca
     2281 agctaacata actgtcaaaa tgcaatgttt gtgttatttt tttgatttta agactcaaag
     2341 attcactgat tttcggtgcc cgtccactaa tttgtaacat agccagtaaa aaagaggaaa
     2401 attcatgacc gagggggata ccagcaaaaa cgattccact ttctttgcca actggattga
     2461 tagaaaaact aggtgtgcgc atcgaatctc ttttttccca agagatttta ggagacattt
     2521 ctgctatttc cttcgtaaat tcagctagtt tttgactatt ttcactatta tccaaactaa
     2581 cagaaaaaac aataggagat tcaatcagtg ctaaatattg ttcgagattt tgtttagttt
     2641 ctttgtctaa catatccacc acctaaatct ttccaacaag atcaaaactt ggtttcaatg
     2701 tttcgccact ttctttccat tttgccggac aaacttcacc tgggtgggta cgtacatatt
     2761 gagcagcgcg aatcttatca atcagtgcac tagcgtcacg accgattcca tctgcattga
     2821 tttccatagc ttgaacgatt ccgtctggat caataataaa tgttcctcgc tgagctaatc
     2881 cttgctcttc atccaaaaca tcaaaaatac gagaaatctg atgagacgga tcaccgatca
     2941 tcacgtattc gattttaccg atagcatctg atgtatcatg ccatgctttg tgagtaaagt
     3001 gggtatcggt agagcaagaa aagacttcaa cacctaaaga tttcaatgta ctgtattgtt
     3061 cttgtaagtc ttctaattca gtaggacaaa caaaagtaaa atcagctgga tagaagcaaa
     3121 gaatactcca gttccccata agatcttttt cactgacttc taaaaattct ccttgatgat
     3181 aagcatgtgc attaaattct tcgatttttt tcccaatcaa tgacatagta aaacctccaa
     3241 taataattat ttatttataa ttattgtaat ttagttggag ttgcaaagtc aatggatatt
     3301 ttgttattta ataaagatta ctcaaaaacg aaggttaatt ataaaaatag aagaggtcgc
     3361 aagaaaatgc tactgctgga aatactcggg ataacgttga gtaacagttt cctgttcttt
     3421 cagcatcatg tgtaagtgca atcccgtttg aaatcgagct tcttctggtt tttttatcaa
     3481 ctaaagcctt gagtaaatca taatgttgtt ccatgatcgt ttcccatgga agcccctgaa
     3541 tggtcactcg taaccagcgg aaacgttcta aatgggtatt atggtcatct aaccagttcc
     3601 aaacttcttt tcttcctgca atttcgaaac aagcttcatg aaataaatta tctgcacgga
     3661 aaaaagcgcg ttcgtcattt attttgactg ctttttcttg ttcttctaaa atcgtttcta
     3721 gcactattcg tgtttgtgtg tccaatttgg aacaacattc aatcatgatt tgctcttcca
     3781 actgttctcg gacaaagcga gcattttctg cagaaacaag attaattttg gaaacatacg
     3841 taccactttg aggtatcgta tacacgagtt cttgctgacg tagttgaatc aatgcttcgc
     3901 gaatgggagt ccggccgata gcaagatgtt cctccagtgc cttttcagat attttccttc
     3961 caggttctaa gtcagcatag ataatttgtt tacgaatcgc ttgataagct tgtgattgca
     4021 agctgctttt catctttatt cctccaaaat catttctatg aacgtagtat aacagaagag
     4081 gtctgaaaaa caatctggta tgtcacatta actagtaaat ttgtataaat agtaaaattt
     4141 tggttgacat agcgattttt attgtataaa attcacttga atacaaaaac taatatgtta
     4201 gtttaggagg ggaaaaatga ttgatttaaa caactggagg aactttatcc ctgaattatc
     4261 tcaaaaagaa gtagaaatac ctcattttga ccgtgcatca ttaagagaaa atggacaaaa
     4321 aaatcctgtc tggatccatt tcggtggcgg aaatctttat cgaggatttc atgcagaaat
     4381 cgctcaacgt ttagcggatc taggcgaatt gtccactggt gtcattgttt gtgaaacatt
     4441 cgatgaagaa ataattgaaa gggcttacca agattttgat gatttgattc ttgaagtggt
     4501 catgccaagc agtggagagt tcgtcaaacg tatattagct gcgacagctg acagtctgta
     4561 ttgtcatcca gattgttctg aacactttga taagatgatt cgacactttg aaaatcctag
     4621 tttacaatta gttacttttg ctattactga aaaaggttat cgattgaaag atacaaataa
     4681 taaatatata ggaccgattg cagtcgatat aaaaaatggt ccaaagaagc catcacatac
     4741 aatgagtatt cttgctgcgc tactttataa acgtttttta tctggagctt ggccgattgc
     4801 acttgtctct acagataatt tttcacaaaa cggtagtcaa ttacgtactt ctttgctaac
     4861 gatcgcaaaa gaatggcaaa aggaaggtta tgtacaaaat acatttatcc aatacttatc
     4921 gaatgaagaa attgttgcgt ttccatggac gatgattgat cgtatcaccc cgaatccttc
     4981 cttgtcagtt agcaaaatgt tggcaaaaga gggcttttca aatatgtcga ttttccaaac
     5041 cgcaaaagga aataatattg ctccatttgt caatacagag gacatccatt atttaatcat
     5101 ggaagatcat tttcccaatg gacgtccgaa attcgaaaaa gctggggtat tcttgactga
     5161 tcgtgcaacg gtagataaag cagatacgat gaaggtgacg acttgcctta atcctttgca
     5221 tacgtcttta gctattatgg gttgtttact ggggtatagg agcatagctg aggagatgaa
     5281 agatccagat ttatcgctgc tagtttctga aatcgggtac aatgaaggcc tcccagttgt
     5341 ggagtctcca ggtatcattg atccaaagat ctttctggaa gaagtaatta ctgtgcgctt
     5401 ttctaatcca aatattcctg atatgcctca gcgaatcgcc acggatacct ctcaaaaggt
     5461 ggcgattcgt tatggtgaga cgattaaaaa atatatggaa atagaagtta aagacccgca
     5521 gacacttgta ttcataccat tgactctcgc tgcttggctt cgatacctta ttggcattga
     5581 tgatcaagga aaaccattca tcccgagtcc agacccacta ttgacagact ttcagcataa
     5641 gctttccgat attcaactgg gtacgcaaga tacatcacat attcatgaga aaatggctcc
     5701 tattttgtca aataaagaaa tttttggtgt agatctttac caagcagagc ttggcagaaa
     5761 aatagaagaa atgttcatca agatggtagc aggaccgaat gccgtacgaa aaacattaca
     5821 ggattactta caagaacatg gaggaaattt atcatggaaa tgacttttag atggtacgga
     5881 tcacaggaag aaaagattac cttagatgaa atcagacaga ttcctgcggt caaagggatt
     5941 gtaggcacat tgatggatat accagtagga gaggtatggc ccagggagag gatcaaagaa
     6001 ctaaaagaag aaattgagtc tcgtgggtta acactaaaag taattgaaag cgtcaatgtg
     6061 catgatgcca ttaaaattgg attaccttcc cgtgagcagt atatcgaaaa ctataagcag
     6121 acaatccgaa acttggcaga atatggaata gaagtcatct gctataattt tatgcctgta
     6181 tttgactggg tgaaatctga ccttgactac cgcttagaag acggctcatc cacgttagct
     6241 tttatatctg atgatattcc agatgatcca agagaaatcg tcgcgcgcat cgaacattcc
     6301 agcaatgaat ttgaattgcc gggatgggaa cctgagcgct tagctcatat caaatccttg
     6361 cttgaagcct atgcatcagt agacgaagaa aaacttcgag aaaattttgc ctattttctc
     6421 caatcaatca tcccaacatg tgaagaggta ggggtcaaaa tggctgtaca tccagatgat
     6481 ccgccatact cgatttttgg attacctcga atcgtaaaga atcgagaaga tttagattgg
     6541 ttgtgccgca tagtagacag cccttataac ggaatcactc tttgtacagg gagtattgca
     6601 gaagatccag aaaatgatgt atatgggatt ttagcagaat tttgtcaaag agatcgaatc
     6661 ccatttgcac atgttcgaaa tattaaattt ttagctaatc gagatttcta tgaggcaccg
     6721 cataaatccg aatacggttc attagacatg taccgcatac taaaaacaat gtatgacaac
     6781 ggatttaacg aatacatccg tcctgatcat ggaagaatga tctggaatga gacaggaaga
     6841 ccaggatacg gcttatatga tcgagcatta ggtgctgttt atctaaatgg attatgggaa
     6901 gcaatcgaaa aaggaaacaa aagtaaagat aattagtgaa aaaaactgta attttattat
     6961 gtaaataaga aggatgttca aattcttgat acataaatcc ggaggttgtt aataagcatt
     7021 cggatttatg tatcttattt ggtctaggaa gtaacttgat tttctttttt cgattgatcc
     7081 atgagtgctt cttcttttaa ttcaaagata tattctgaga tcctcataat cacttttttc
     7141 cagtcttctg gtgtgatgat tccttttaaa atatagattt ttttgatatg agaaggcaat
     7201 tgtttcaaag ggcagtcgct gataacgatg ttgcagttct ccataaaatc attttgtatt
     7261 ttgatcgatt catttgaaaa aatttgttct atcttaacga tcagatcttt actgatataa
     7321 aaatcacgcg tatagttcac accaatcaca attcgcggct gttttttgta gcgatcatac
     7381 aaatgtacta ggtcttcaac catccattgc acattttcct tttctaaaat aactggtaac
     7441 aagtgttgat tttgttctct gaaatccata taaaattgtt caatggcggt ttggacttct
     7501 ttcaacacgc tatgttcttg ataaagcatg aaagtaggaa ggggcgtatt tggttgattg
     7561 aagttaagaa atccattata aagtttattt cgtgcgaatg ccaatgagta aagaatcttt
     7621 tctttttcag gtataaacaa atcaaataca gtacaaaagg actccaccat ttctcttgaa
     7681 taaagaacat gaggaacgtt tgcttttttt aaaagtttgt attgctccaa gcttgtttct
     7741 tccgattcga ttttcgtgat agaaagtcga gctaaaatat tcactaagat gcgttgttcg
     7801 cgacaaattg gcagattagg tcgcaaaata tctacagagg gatcaataaa aaagtcaata
     7861 tattcatact ctgtgaattc tttttgtacg tctttcacag aagttgcagg
//
LOCUS       DAFTHM010000112         7903 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFTHM010000112 DAFTHM010000000
VERSION     DAFTHM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.112"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(21..995)
                     /locus_tag="L7C88_002427"
     CDS             complement(21..995)
                     /locus_tag="L7C88_002427"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBP9559221.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(1075..1950)
                     /locus_tag="L7C88_002428"
     CDS             complement(1075..1950)
                     /locus_tag="L7C88_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBP9559222.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            2080..3987
                     /locus_tag="L7C88_002429"
     CDS             2080..3987
                     /locus_tag="L7C88_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBP9559223.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(4528..7806)
                     /locus_tag="L7C88_002430"
     CDS             complement(4528..7806)
                     /locus_tag="L7C88_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBP9559224.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLESYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT         2236 a         1665 c         1465 g         2537 t
ORIGIN      
        1 tctttccctc ttttttttgt ttattcgaat tctttttctt ccagacggaa taacggactc
       61 atcggtgtat tttcatggat gcgtttgacc gcttcaccca ttaattctga acatgtaacg
      121 attgttaagt tttctggatg acgattttct tctgtgaaaa cagaatcagt gatacaaata
      181 tctttgattg gtgcattgtc taaaatactt ttcgcatgat cggacaataa tccatgtgac
      241 gcacaggcat atacttcttt tgcgccgttt tcttttaata catttgctgc tcgtgcaagc
      301 gttgctcctg tgttcaagat atcatctacc atgatacatg tctttccttg aacatcaccg
      361 atcacataac caccctcagt tgaagcatca tctgcatgat ctacgatggc taatgtgctg
      421 ttcaaatatt ctgaaagact acgtgcacgc tgaacaccgc tgttttttgg cgaaacaact
      481 acgatgtcat ctcccgtcag acctaattga cggtaataat gagcaaacaa cggcatcgta
      541 aataaattat ctacaggaat atcaaagaat ccttgtactt gaaccgtgtg cagatctaaa
      601 gtcagtactc gagttgcccc tgcttcttcg atcaagttag cgatcaattt cgcagtgatc
      661 ggttcatgag gtttcgccgt gcggtcttgc ctagcatacc catagtaagg caatacgaca
      721 ttgatcgttt tcgcacttgc tcgcttcatt gcatcgatca tgatcagtag ttccatatag
      781 tagtcattga caggtgcatt cgttgattga acgatataca catgatcccc tcgaatactt
      841 tcttcgatat tgatggaaat ctcgccatca ctaaattgct tcacgacgct tttacctaat
      901 tctgttccga acactttcgc gattttttca gctaatggac ggttgccatt caaactaaaa
      961 atcttcaacg tgtcatcctg atacttatta ctcatgtagt cctccccaaa acttctctat
     1021 tcttcgatag tttaacatat ttttccaaga ttttctgtta atttcagcaa attcttaagg
     1081 aagtgaaact gttccgttac tccaactggc aggaatgact ttatgataat cgccccagtt
     1141 gtcgtgtact ttgtaataac gttctcctgt ttcagtttca aaataagcgt acgctgtcac
     1201 ccaatgattg ccatatgtac tgccaagtac tttcaaaata ccaatcatca caggtttgcc
     1261 ttcacgtata cgttttgtag ctcgctgcca tgaacctaga agagttgctc gtgcacgctc
     1321 atgattgcca ttcttcttta aaaaactaga aatccctgta ctaacctgaa aaggaatcgt
     1381 aggaagtcct agtggttgga tctggctacg caatgccttc gtcaaaacca acgaatcagc
     1441 cgtatttttc ttgcgaatct catttggaag catccacccc ttacgatagt cttgataata
     1501 ggcaaggaga actgctgccg cgtaagtacc acaaagatag cctgaggggg tagcccattt
     1561 cttatacctc aaaaaacgtt cttctggcaa tcccacccag caatttgcga gttcctttcc
     1621 tgaccttttt tcttcgatca aaacgggaat atcttctttt ctgttgatcc atctagataa
     1681 ctcgattggc tcttcattga tcagcttcca ttttttacaa gaaagaccct cttgataagt
     1741 atattttgct ggagaatatt ctaccggatg tcctgattga tcgataatca cataactttg
     1801 atcttcaaaa accagagcta aaaaaagcaa tttacttttt cttgactgca gctgctgagt
     1861 gctggctaat tttttaattt ttttatctac tttgaaatat aaaggtttat ccactacttg
     1921 attcagttgg gatcgcctcc tttttttcat tataagtgaa ggattgaaaa aaacaaatca
     1981 gtttgattgt tcgaattttc aattttttat gttctatttg ttaattcctt cattttgtaa
     2041 gataatgggc acacgaaaca aaaaaggagc gatcgatgaa tgaacaaaga acgattgaaa
     2101 caagatttct atgaagcagt caatgaagaa tggcaaaaaa cagcaaaaat ccctgcagat
     2161 aaaccagcta caggcggttt ccaagattta gttgacggga tcgaccaact tttgatggga
     2221 gaaacagacg atctgcttgc ccatccagaa aaagtgtctt cagaaaaaat gaaacatttc
     2281 cttgcatatt atcaactggc aaacgattat gaccgaagaa atgagttgca tgctcaaccg
     2341 cttcaaccta taatcgaaaa agttgaatca ttgcagtctt tcgacgaatt gaataagcaa
     2401 tttccagaat ggctgttgga tacattacca ttgccattta atctggatgt agatgcagat
     2461 atgaagaatg cgcaaacgaa cgccttcttt gcttatccgc cttctttatt ccttccagat
     2521 aagacgtatt atgcatcaga ccatcccaac ggtgcacaac taataggcgt tttctttgat
     2581 atggctgttc agttattaga gcttgccggc aaagaaaaaa gtcaggcaga agcaatcacg
     2641 gaacaagcag tgcaatttga taaattgatt gctcctcatg taaaaagtgc agaagaaaac
     2701 gcagattaca gcaaaatgta taatccgcaa tcttttgata catttattaa atacacagat
     2761 aaactggact tgaaaaaact tgtcacgggt ttgattggga caactccaga taaagtgatc
     2821 gtaactgatc cagtgtactt cgatcatttg aatgacatcc tgacagaagc tcattttccg
     2881 ttattcaaaa gctggatgat cattaaaaca gtacgttctc ttagtggtta tctatcagaa
     2941 gaattccgcc aagtcagcgg aatctattct cgcgtattgt ctggaacaga cgaagcaatg
     3001 cctcagaaaa aagcagcgta ttaccttgcc tctggacaat tcgatcaagt agttggcgat
     3061 tactacggaa aaaaatattt tggcgaagct gctaaaaaag acgtagaaca aatggtgaaa
     3121 aaaatgatcg ccgtttataa aaaacgtcta gaagaaaatg actggcttgg ggatgcaaca
     3181 aaagaaaaag ccgtcataaa attaaataac ttaggtatcc aagtaggcta ccccgataag
     3241 atcccagcat tattcgacca gttcaaaaca gtacctgcag atcagggtgg tactttgctt
     3301 tcaaatactc ttgttttcag caaactcaca ttaaaagatc gtttcagcaa atggaacaaa
     3361 ccagtggatc gttcagaatg ggaaatgagt gctgacacgg tcaatgctta ttatcatcca
     3421 tttcggaatg tgatcgtctt tccggcagcg atccttcaag caccatttta cagtctagaa
     3481 caatcaagct ctgctaatta tggtggaatc ggagctgtta tcgctcatga gatttcccat
     3541 gcatttgata ataacggcgc tttatttgac gaatatggca acttgaacaa ctggtggaca
     3601 gaagaagatc ttacacaatt tcaaaacaaa gcacaagcaa tgatcgaaga attcgatggt
     3661 ctgccttttg ctgacggaaa agtaaacgga aaattaaccg tttcggaaaa tattgctgat
     3721 gcaggcggtc taagctgtgc attggaagca gcaaaaacgg aatcagatct ttctatcgag
     3781 gaattctttg tcaattgggc aacgatttgg cgtacaaaag caaaaaaaga ataccaacaa
     3841 cttttactgc aaatcgatgt ccatgcccct gctaaactcc gagcaaacgt gcaaccaaaa
     3901 aaccttgacg aattctatga aacatttggt atcacggaac aagacgctat gtatctagcg
     3961 ccagaaaaaa gagtgcgaat ctggtaagag gttgtgccag aagtggtcag cttcaagaaa
     4021 taagaaggaa tttgggaaaa tcgcttctca aatttttgtg acatttcggc ttatttttcg
     4081 aagaagttac ttctggaata ccatgtatta gaggttgtga aaaagctgct tagtttcaag
     4141 tagtaagaaa aattttgtga aaatggcttt ccacattttt gcataaattt gacttactac
     4201 cgagaaactg gcttttgaac accgtttatc gagaggttgt gaaatcagcg tcctgacctg
     4261 agtattagag aaaaaaacgg aaaaatagtt cctcatattt tgccgtttgt tgagctaata
     4321 ccgagggtca gctgattgaa caccgtttag tggagagatt gtgaaaaagc tgtcctgcat
     4381 caagtaataa gaacagccaa tcaaaagcag caaggagaac ctcatctata aaaagataga
     4441 aggaagtgag acatctattg gtctcatttc cttctatttt tactttcctc agtcaattgt
     4501 tttacatcat aaaaggagaa attccactta tttttttcgc tgtttcatga cataaacaac
     4561 tacaccgatt aacaaaattc ctccagctaa tgctagcaac gggttattaa attctcccgt
     4621 ttttgggagt ccttgagtgc catttttttc actttctttt gctgtcctat ccggatgaga
     4681 aggttttcca tttggttttc catttggtga ttcatttcct ggattttctc tttctggttt
     4741 gtcatttccc gggggcacat cggcagtttc tcgcacagtg atcgcttttt gctgggtaac
     4801 agattctgta tgagcagacc atttttcccc atcaaatatt tccgaacgat aagtgacttc
     4861 tagcgtatat tctccttttg aaggtgctga aaaaatagcg gtatgattag aaaattgagc
     4921 acttgactgt gtttcaacga tttggatctt ttctgggaaa taacgcatat cttcaaagac
     4981 aggcgttcct tgatttggtg tgaaagttga cacaaaaact gtaaaaggct tcagttcaat
     5041 gatatttcct tctgcattct ccgccacacc atttgcttct tgtataataa tcggattatt
     5101 ttgttcattt ggttttgtct gatttggttc ttgtacgatt gcatactctg gatattccga
     5161 agacggtgag gtttctccgt caaaaatagc acctacagat aatggaagac catccactct
     5221 ttccttttct gtttgacgat tccccggttt aatctgcatc agtccatgaa catggatact
     5281 tccattttca tagcgcgtaa caggctgctg accttctttc gaacatgtat ttagagactc
     5341 gatccaatct tttgatatgg tatgtccaag agtattttct gattgtttct ctcgttcatt
     5401 ccaatagtag ttcaacgagt ggtagatttg atcttcgttt tgattcaatg ggcggatctg
     5461 ctctctcatc tcaagattct ctgttcggaa agataagata ccagaagcat ggtagtctgt
     5521 gtttcctgct gaagaggtat aaagagccac attatatgaa ccgttattaa aacttgtact
     5581 gctattgacg ataatatctg ttccgctatt ggaatcgatt cctttcgcaa gattttcgaa
     5641 agacaaacta ttgatcaatt catgagggcc cgttaaagaa gaaccgccca ttttgaatcc
     5701 attaccgtta ccttctccct caattcctgg tacccagccg tttcgataag caactgagtt
     5761 tttgatgatt acttttccga tcgaacctgt ttcattttta gcaaaaaggt cccaaccgtc
     5821 atctgcatta tgatacgcga tacaaccgtc aaatacattt ccttctccta ttgtcagttt
     5881 ggccgcaaat ccatcggcat cttcaaatcc tggatcggca ttttcaaaag atgtacagtt
     5941 cttgactaag ttatgcgcgg gccatgcttc gaaaggatca tttgagctac cgctgatttg
     6001 gattcctgta tttccattcc gataagcatg aatctcttcg atcaaattat gatttccaga
     6061 aatctgtaat cctttttgca tagctgcact atttgtaatg tcaaaccctc gtaaacccca
     6121 gtagtgactg aacagtgtca tcccatttcc agttccttta aaatcaagta caggacgctt
     6181 gttttctgga tttttctctg caatcaactg aatcgggttt tctcttgtcc cgttaacgcc
     6241 ttttggaatc gtcaatcctc tttcgaagga ataagttcca ggcgccatga cgattgtctg
     6301 cccagcatat gcgtatctca atgcttgtgt cagagataat ggattttgtc tgcttccgtt
     6361 tcctgcatct gacccttctg gtgttacata aactgtcgaa tatttaggtt tacggtagtc
     6421 cactgtatga agaatctctt ttgtttcata actagtcatc tctacgtatt cttctggcgg
     6481 atagttttta tctggcgtaa aactgaaagt aaattcgttc gttccttcca tcagttttgt
     6541 ctgataatca aattcccgat tcgcagtgat agccaagttt tttgcgttct taagcacctc
     6601 tcctgttgct ttatttttaa ttgtcaataa tccgtcagca tttgctctaa aggacatagt
     6661 atgatcttgg tttcctgaat gattactaga ggtcacagtg taaatcggat caatcaagcg
     6721 agtaggtctt tcttgcccag gaggatctgt cgcaggatct gagtaagcaa cttcgattcc
     6781 ttctaccttg atcgtcatat tccttgctgc agcaaatcct gcataaataa ccgattcatc
     6841 tgaagcgtat aatttttccc agtcatacat gatgtcagaa gccatttctt ctcctgtttc
     6901 aggatcgtaa taatatgact ctaaaccagt attcgttttt ttcatctcta cgtccagttt
     6961 agtaatcgag ttcgtggccg gaaacaaatt cccatgaccg tttccgaata tattataaga
     7021 acctgtttct ttttccaaga accctgctga agtctctaaa ggtgttgttt ccactgagac
     7081 actcccagga gctggcgcag cttgcggatc ttcagatgat attcctgtga ttgcccgtgt
     7141 ccccaatcca agtcgcatcg tatatttgct gccgctcgtg ttgaccactt cttgtctatc
     7201 cgagtcccag acatattcga tccgactgcc tagtatggca aatgaatttg aataaaatgc
     7261 ctgcccaaac aaatgatttt ttggtactgc gtctcttacc attaaagcaa atccttcttg
     7321 ggcattcgta taggtccaag attctatttc gatcgtcgcc cgcatcctaa agttgatgtc
     7381 tttggggatt gcttgataat aataggtcat tccatctgat ccgcttgact ggaattttcc
     7441 gccgttattc gtggaagaga gccgcacgcc gtcttctaat ggttcaatgg catacctact
     7501 agcacttgtg ctttctccga aaacaacccc tttccactct tcatttgctt cttcagattg
     7561 cttttttgtc ttttcatttt ctgattcttt catcatagga tcatttcctt cttccgtatc
     7621 catatcttca ctagttcttg gtacttcctc cattgttgac atcccttcaa tgttcacgtg
     7681 tgcattttct tcgttcacag actgttgttc gttagcagca acttcaacga cagaaattaa
     7741 aaccggggta ctgagcataa ggagattcat cattagcgca ctgtatttta tacgtttttt
     7801 taacaagtgt attcctcccg taacaaatta gaaagcgttt acttaaagta ttacctaatt
     7861 tatttttact gtcaataaaa aacaaaatta taataagtgt att
//
LOCUS       DAFTHM010000113         7285 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFTHM010000113 DAFTHM010000000
VERSION     DAFTHM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.113"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..696)
                     /locus_tag="L7C88_002431"
     CDS             complement(<1..696)
                     /locus_tag="L7C88_002431"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBP9559225.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKK"
     gene            complement(933..2456)
                     /locus_tag="L7C88_002432"
     CDS             complement(933..2456)
                     /locus_tag="L7C88_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBP9559226.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(2834..3445)
                     /locus_tag="L7C88_002433"
     CDS             complement(2834..3445)
                     /locus_tag="L7C88_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBP9559227.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(3568..3693)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(3775..4491)
                     /locus_tag="L7C88_002434"
     CDS             complement(3775..4491)
                     /locus_tag="L7C88_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBP9559228.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(4497..5066)
                     /gene="scpB"
                     /locus_tag="L7C88_002435"
     CDS             complement(4497..5066)
                     /gene="scpB"
                     /locus_tag="L7C88_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBP9559229.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(5050..5847)
                     /locus_tag="L7C88_002436"
     CDS             complement(5050..5847)
                     /locus_tag="L7C88_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBP9559230.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(5817..6188)
                     /locus_tag="L7C88_002437"
     CDS             complement(5817..6188)
                     /locus_tag="L7C88_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBP9559231.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(6207..7094)
                     /gene="xerD"
                     /locus_tag="L7C88_002438"
     CDS             complement(6207..7094)
                     /gene="xerD"
                     /locus_tag="L7C88_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBP9559232.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         2084 a         1574 c         1232 g         2395 t
ORIGIN      
        1 ttttttcaat gcttctttta cttcagaaag cttttctcca gagtaaggag ctgcatcagg
       61 aacaacattc aacgctcctc cagcttttac agaaaactcg ttcgttcctg gtcctgtcaa
      121 gtaagcttgc aataagcctt tttctgcata aattaaagga aattcagcat ctggcgcaaa
      181 tccttgcgta attccttctt ctttttcgtt atatttttct aaacaacgcc ataaattttc
      241 ttcatctgta ccaaagataa aacgaatacg tgtcttgaat tccacgccag catcaatcaa
      301 agctttgacg gcatacattg ccgcaataga aggacctttg tcatcttggg atccgcgacc
      361 aactaaccag ccgtctttta tagttggatc gaatggtttt gtttcccaat tattttcgtc
      421 ccctgctgga acaacgtcca tatgacacaa gataccgaat aattcatctc cagagccaat
      481 ctctgaataa ccgtaatagc cttctggatc tttaaatgtt ctaaatccta gcttttcact
      541 gatttccaat actttatcca aagcttcaat cactttttta ccgaagggat gtccttgtcc
      601 tgaatctgct tcatctagta cggaaggaat tcggatcaat tcgctcaatg attctaatgc
      661 ttgttcatga tgttgttctg tcacaaattt tttcatgata ttatcctcct aatatgttaa
      721 aaagggtcat gtcaaattcc tccgacacaa cctcttcttc tcaaataatg acgttttaag
      781 cctgctccat cagcaagcag aatgttctta acaaatgatg aaagaaaaaa cactcactga
      841 atggagctat tgacttgtcc acgtgcttat cgatagccgt ttatcggttt cttcattctt
      901 atgatagacc ttgtacctgt atttgtctag gtttagaaca ttgctgctac acctaggatc
      961 acacagatgg ctacaaataa tatcgcaatt aatttaccgg taaatttcca ccacactgaa
     1021 acatcgaaac gagcaattgc tacagcaccc attacgatag cagatgttgg tgtaattaag
     1081 tttactaaac cagatgcaga ttgataagca gtgattacta aatccttacc gacgccggca
     1141 aattcaccca taggtcccat gattcccatt gttgcagcag ctaagccgga agttgaagga
     1201 atcaagaatg acatagggat atagaaaata aatgtaataa tgatgaatac acttgaagat
     1261 aatgaactta atccttgttc gccccaatgt aagatggtgt ctgtgattaa tccattgttc
     1321 ataaccactt ggataccacg agcaacagct actacgattg ctacaccgat caaatcagaa
     1381 gcaccagcta aaaattcaga gacaaattca gactctttca tgccataagt gattgctact
     1441 acgatggaca ttactaagaa taacatagta atttctggga agtaccagtc acctaatgga
     1501 agcatgcttt tacctagaac cgtacctagt accggaaggt ttgttaacca gtttgtcaat
     1561 gattcaaaaa tcgtgaaatt cgcattcaag gttgtccaag gaatcaaact gatgatcatg
     1621 ataccaaaag taataaagaa caatacatta acatgttttt gttttttcgt gattacttct
     1681 tgacgaccga ttgcttcaat atcgaaatgc ttcatatctt ctttacgttg gttgtatact
     1741 aatgattttg ttggatcttt ttcgatcttt gatgcataac gatacacata tacaatagaa
     1801 atagctaaca aaataacgaa catcaagaat cgaagaccaa taccttcacc catcgaaatc
     1861 ccaacagctt gtgaagctac gcctgttgca aaaggattta ccgttgaagc tagacagcct
     1921 acttgagacc ctactaatac gattgctaca gctactactg tatcaaagcc tacagccatc
     1981 atgactggga tcagtaaagc atagaatgga atcgtttctt ctgccattcc gtaagtagag
     2041 ccgcctaatg caaataacag catcaatact ggaataagca ttttttcttt tcctttgaat
     2101 ttcttcacaa ctgaagcaat cccggcatct agtgcccctg ttttgttgat aatacctaaa
     2161 aatccaccaa caaccaaaat gaagaaagag attgggattg cagcaggtgt ttctttagtt
     2221 agctcccccg ctggtacacc tagcatccca ttgattggcg ccatgaaaat atcccacagc
     2281 ccttgaggat tttgttgtac tcgttcatat gatccagcga cgatgttgcc tgcatcgtct
     2341 acactatagt gcccagctgg tataaaccaa gtaagtacag cgattactgc aataataata
     2401 aataagaccg tatacgctga aggcatttga aattttttct tttttgtttg ttccatcttc
     2461 ttcttccttt cttttccgtt agagacaaca attttggctc taatgttatt ttatcaaaaa
     2521 gagtatcaga acaaaaataa taacacgcat tttgtaaaac ttttgttcaa aaagttcgtt
     2581 tttccctatt ccctcctctt ttttcagttt tttaaagctt tcttcttttt cattgtagcg
     2641 tttccttttt tttataaaca aacattttcg tcttttaaaa ggagaagaat ttcacatttg
     2701 caaagaattg attgattttt atgcataaat caaaaaaata ctcaaaacaa acaaataaaa
     2761 cgtttacatt attgcatgtc ttgtattttt ttccaaaaaa aaagaccaag aaatttcttg
     2821 atctttttga tatttatttg actgctgtat gacgttgttc gaactgatgt tgttttcgac
     2881 ttaaccatgg aagaagttgc gcatgcagca ctaaaaagac agcactcacg atgaatcctt
     2941 tgatcaagtt gaaaggaacg atcccaatca gtacatagtt tgctaaagac atgcccagca
     3001 tctgtgttgc gttcagccct aaaaacatta agtaaagagg cgtaataacg aaataatttg
     3061 cgatactcat aaaaatagtt agagcgatgg ttcctgtaat gacacctaaa aatttgtttc
     3121 ttcctttatg ctgtttcttt acactaaaga aataataaat cgggaatgta aagatcgttg
     3181 ttgataagaa actagcagtg tctcctacca aattatccgg agaaaaacct gtagtcagca
     3241 gatgtaatac tgaacgcaag aacgctgttg caactccggc cgctggaccg aataagaaca
     3301 tgctgatcaa taccgagata tcactaaaat cgatcttcaa aaaactaaaa gccggcatga
     3361 tcggaaaagc aaaatactgt aaaactaatg cgatcgcagc aaacatcgct actgcaacca
     3421 ttttctgtac acgggtgttc ttcatttgaa atcctcctgt taggactcct cttcagcgaa
     3481 ctttttgacg tttctctcca aatgaaaaaa ctctattttc cagggaaaat agagttagag
     3541 ttatttgatc aagcgtcgtc aaataagctc tatcttcttt atccagacta tactgtcggt
     3601 atcggaattt caccgattca gctatttttt tgcaaaatag gtcgtggact ataaccaccg
     3661 gtcgggaatt tcaccctgcc cctgaagacg aaccttatat aatttttgtt tacatattca
     3721 ttatacatat ctattcaaaa aacgcaacat ctaacaatta taaaaagtaa gtgttcattt
     3781 tgagtggttc agcaaactgc tgacttcttt tttgttcagt tcacggtaat ccccaggacg
     3841 taggccttgt aaagtcagat ctccgtattt ttcacgtttt agtttttgca caggaagacc
     3901 aactgcttga agcatatttt tcacttgatg attacgtcct tcgtggatcg tcaattccac
     3961 gatactgtgg tttgtcttag gatccactga taaaatttgg aatttagctg gagatgtttt
     4021 tcgtccttcg atctttattc cttttgtcaa aggtgcaagc atcgattttg tagcgatccc
     4081 ttttaccttt gcaacgtaaa ctttatccac ttcatgtttt ggatgtgtca ggcgctgagc
     4141 aaaatctcca tcatttgtca gtagcaagat ccccgaagta tcgtaatcca gtcgacctac
     4201 aggatagata cgttctttta ccatcggcaa aagatccgta acaacttttc ttcctttgtc
     4261 atctgcaaca gcagaaataa ctcctttagg tttgtacaat aaatagtaac cgtattcttc
     4321 ttgataaatt gggacttcat ccacttccac agtgtcatgt ttcccaactt ttatccctaa
     4381 ttcccttaca acttgtccgt ttacttttac acgtcctgca aggatgaatt cttctgcttt
     4441 tcgacgagaa gtgatgccag cgtgggcaat tactttctgc aatctctcca ttacaattat
     4501 tctcctttat tcattccatc aaagaataga tctggtgaca cgtcttcttc aagtgaaatt
     4561 tccatttctt gtgtatcagg cagttcttct aatgatttca aaccaaaata atctaagaag
     4621 tagccagttg ttccatataa tatcggccga cctggtcctt ctactctacc tttttcttca
     4681 atcagtttat gggcagctag acgctgtacc gctcctgaaa cctgaactcc tcgaatctgc
     4741 tcgatttcag ctcttgtgat tggctgttta taagcgatga ttgctaaggt ttcgacggcg
     4801 gcttgagata atgtgtttga tgtcccttgc gcatatcgct taagtaaggg agccagctct
     4861 tttttagtcg ttaatacata atggctttcc gtttcaaaaa tatgcaaagc tgagtgcgag
     4921 ttttgagtgt aagattcttt taattctttc actaaacttg tgacttctgc ttcgctgaga
     4981 tttaacagtc cgcttaattc ttcattactg atcccttcct cgccaacaat aaaaagaagg
     5041 gcttcaagtt cacttaattt cgtcatgttc ggtatctcct actgctggat aaagcataat
     5101 tgattcatag ttttcttttt gttgcgcaat gatctgccct tttttcatca attctagcaa
     5161 agccataaaa gtagtgacaa cttcactttt agaaggtgac tcaaaaaaag aatcgaaagt
     5221 acagccatgc gcatttcttt ttatacgctc ttcgataaat accattcgtt cttcgatcgt
     5281 tgtgtcatcg ggcgtgatcg ttttttccac tttttgagaa aatttcttac gttctaagat
     5341 tttctgcatg gcacggatca aatcgatttt tttgacttgt cctcgcttca acggcttttc
     5401 agcatccgct aacccatcga tgttcatagg ttcttttgtg taataaagac ttcgttcctc
     5461 tgctttttct gtcagtcttt cagctgcata tttatattta cggtattcta aaagctgagt
     5521 gaccaattct tctcgaggat cttcttccca taattcttca tcgtctgtgc cgaattcttg
     5581 gacaggaagc aatgtcttgc ttttgattgc catcaatgta gcagccatca ctaagtattc
     5641 tcctgcaaca gctagctcga gtgttttcat tgtatggata taattcatat attgctccgt
     5701 gatcgtagcg atcggtatat catatatatc gatttccatt tgctgaatca gatgaagcag
     5761 cagatcgaga ggaccctcga atacatctaa tttaatattg atctccgtca actcattcac
     5821 tctttcttct ttttctttgc tagccatttt ccaatgtaag gctctgtgat ttcagttgca
     5881 cggatggaga catccgggta cttttcctgt aattcatcta acatttgaaa gcccatattc
     5941 tcaccgcgat aagacggatt caaagaaatg tcatggatga tcagctgatc gttcgttgcc
     6001 cagtaaatac caataatccc ttgaatgttg gttgaacctt ctggcgtaaa gaaaaaaagt
     6061 tcataatcgt cttcagattc gtacgtatca atctccttca acaaagaagt tttacctgtc
     6121 agtttcttat ggaaactcaa tagtcccata gcaattttac ggttttcttt ccggtaatgt
     6181 gttaacatct tctcaccttc ctatgactaa gcccttggaa aatgctgctt ataaacatcc
     6241 gtcattcttt tcttcgtgat atgtgtataa atctgagtcg tagagatatc cgcgtgacct
     6301 aacaattcct gtactgtccg caaatcagct ccattttcta gcagatgtgt ggcaaagcta
     6361 tgccgcagcg tatgtggtgt tacttctttg taaatcccag cctctcgtac taactgcttc
     6421 agatttttcc agattccttg ccgagaaaga cctttcccat gattattgac aaatacatgc
     6481 atttcagatg cgtcctttac aagtaatgga cgtgcttcgt ctaagtagcg ttccagccat
     6541 tggatcgcat aatcacctaa aggaatgatc cgctctttat ctccttttcc aactgtctgt
     6601 accagtccaa gagaaagatg aagatctccc aatttcaatc caatcaattc actgacgcgc
     6661 atcccagtag catacatgac ttccaagatt gcacgatctc ttatccctaa cgtttttgtc
     6721 gtatcaggtg cttcaatcag cttttctact tctgtcagag tcaatgtact tggtaatttc
     6781 tgtgctttct tcggcgtatc gatatgttgc atcggatcat gatcagtgat acgctcttgc
     6841 cgtaaaaact gatggaatct tctgagactt gagatcatcc gagtaacagt tgctgtcgct
     6901 tttttttctt catgcaactt ctccagaaaa cggatgacta aaaagcgatc gacatcctgc
     6961 catgaagcaa ttttctgctc ctgtagaaaa tgcaagtact gttccaaatc acgttcatag
     7021 ctttgtcgtg tattggcgga caatccccgt tcaatattca agtagtggag ataatcgttg
     7081 atttgctctt tcataataat ccccctcatg cctctctatc atatcagata ccgcttcatt
     7141 ctgatagtct ttttccataa tctgagcaaa gaaaaagccg tctagacact cagacggact
     7201 ggtttctttt ttcggctcta taatttatgg gactgatgaa tcagaattga ttcttcagcc
     7261 ccattttcat tttaggtatt aaaaa
//
LOCUS       DAFTHM010000114         7039 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFTHM010000114 DAFTHM010000000
VERSION     DAFTHM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.114"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(279..494)
                     /locus_tag="L7C88_002439"
     CDS             complement(279..494)
                     /locus_tag="L7C88_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HBP9559233.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(513..749)
                     /locus_tag="L7C88_002440"
     CDS             complement(513..749)
                     /locus_tag="L7C88_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HBP9559234.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            1007..3160
                     /locus_tag="L7C88_002441"
     CDS             1007..3160
                     /locus_tag="L7C88_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HBP9559235.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            3129..4544
                     /locus_tag="L7C88_002442"
     CDS             3129..4544
                     /locus_tag="L7C88_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HBP9559236.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            4577..5611
                     /gene="sppA"
                     /locus_tag="L7C88_002443"
     CDS             4577..5611
                     /gene="sppA"
                     /locus_tag="L7C88_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBP9559237.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            5613..6134
                     /locus_tag="L7C88_002444"
     CDS             5613..6134
                     /locus_tag="L7C88_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBP9559238.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            6131..6517
                     /locus_tag="L7C88_002445"
     CDS             6131..6517
                     /locus_tag="L7C88_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBP9559239.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
BASE COUNT         2466 a         1055 c         1273 g         2245 t
ORIGIN      
        1 gtacattacc aatacctcct gtaacggccg aaataggtcc tcctgcagca ccaactacag
       61 cgctgcaagt ccttttgtaa aaatatctct accattacat ttccaaagaa tttttatctg
      121 actttaataa aagataaaaa tttaatataa ttataaaaac tagcacaaga agctttagta
      181 aaaagttctg tccattccaa acttttgaaa agataaagaa catacctatg ttcgtaatcg
      241 acacaaacca atcttgaggt ttgatatttt ttaattgttt acgcaccggt ccacatgctg
      301 aatccagcac ctaataaagc tccacctaca ccacaagcag ctattgcata aggtcctccg
      361 gctgaacaaa gttttactcc tgctgttgcc ccagaaaaag tagtgcctaa aactcccacg
      421 gcactcccac cttgaatatt tttcaactct tctgaagata atataaatgt tgtttttgtg
      481 tttttaatat gcatactact tattctcctt ttttattttt ttcgagcatc ccagccagct
      541 gcagcacctc cagcgacagc tccatataac cctccaacaa caccgcaagc tggtccgcaa
      601 attgctgttc ctaaacctgc accacctact gcccctgtgg taagtccacc tacaacttgc
      661 cccaattttc cccaagcatt attgcctcca ccaacagttt gtgcatttcc acaatactta
      721 gttcctttac attttgcatg tttaaacacg cttctttaaa taatattttt tacggtgcta
      781 ctgtaacata cgtatttgat taacagtaaa aatcttcctg aaacttatca agtttattct
      841 tgaatagtaa aatttccaaa ataaatttga ttcaggaatg aaaaagttag tgttcaagaa
      901 ctgttttcaa agtttttgtg gaattatgag acaatatttt cactgtatta aagctatatt
      961 gagaattttt ctataaaaat tttttagaag gagttgtgtt agataagtga taaaatcatt
     1021 tccttttgtg cagcaacaag atgaaaaaga ttgtggtgtt gcttgccttt cgatgatttt
     1081 aaaatatttt aaaactgata tcccgattca taaattacgg gacctatctg ggactgattt
     1141 agagggtact tcagcatttg gattgaaaaa gacatttgaa aaattgtctt ttgattgtat
     1201 ggctattcaa gcagatagtg agatctggaa agaaagagat cttatcttac cattaattgc
     1261 acatatattg gttgataaca gctatatgca ctacgttgta atttataaaa cgaagggaaa
     1321 cgtactatgg attgcagatc ccgctaatgg aaaaaataga aaaacgattg aagcgtttca
     1381 aaaagaatgg acaggtattc ttttattacc tatgcctaga gaaacttata ttcctattaa
     1441 agaaaaagta gctggattaa gttctttttt gcctataatt tggaaacaaa aaggattagt
     1501 attccacatc gttttagcat cgattttcat tacgtttttt ggcataggaa gctcatatta
     1561 ttttcaaggt attcttgatt ttttcatccc taatcaagca cgttcaactt taaatataat
     1621 ttccattggc ttgatcgctg tctatttatt tcgggtattg tttgaatata gtcgtagtta
     1681 tcttcttatt attttaggac agcgaatgag tatggcaatt atgcttcagt atttcaaaca
     1741 tgtgttaact ttaccaatga atttttttgc tacgagaaaa tcaggggaaa ttatttctcg
     1801 ttttcttgat gccagtaaga ttattgatgc tttagcaagt gctacgttat caatattttt
     1861 agatattggt atggtgttgc ttgttggggt tacgttagct attcagaata gtacgttgtt
     1921 tttaatcact ctatgctctt tgccttttta tgtagttgca atattcgctt tcgtgaaaag
     1981 ctatgaaaaa tcgaacaggg aagaaatggc agccggtgca gctgtaaatt ctagtatcat
     2041 agaaagtctt aaaggaatag aaacaattaa agcatatagc ggtgaagaga aagtatataa
     2101 ccgtatagac catgaatttg ttaaattaat gaaaaaatca tttcgtacgg ttacgcttga
     2161 taatattcaa caaggaatta aacatttgat tcaattaatt agcagtgcat taattttatg
     2221 gctaggttct tattttgtta tggataatag aattagtcta ggtcaactta tcacatacaa
     2281 tgctttacta gtatttttga cagatccttt acaaaacatt attaatttac aagtgaaaat
     2341 gcaaacggct caagttgcaa ataatcgttt aaatgaaatt ttcgcgattg attcagaaaa
     2401 atcgaaccag tcttttgaat atatgctttc tgaacaatta tttcaacaag atatcactgt
     2461 aaaaaacgtt tcattctcgt atagcatgaa ggccccaacg ttgaacgaaa tttcatgtac
     2521 aattccttcg cacagtaaaa cggctatagt tggagttagt ggttctggaa aatcaactct
     2581 tgcaaagtta tttgttcgtt tttatgaagc atcagaagga tcgatccatt atggaaacat
     2641 taatcactta gacattcctt ttcagatatt acgcgatcga gtgacatatt tgcctcaaga
     2701 gtcatttttc tttagtggaa caatcattga gaatcttata ttcggtttag atagcccacc
     2761 aagtttcgaa caaataatag aagtttgtga gatagtccaa ctaaatgaat ttattaatca
     2821 acagccatta cgttacgaga cattgttgga agaaggtgga aataatcttt caggagggca
     2881 acgacaacga ttagccttag cacgggcttt attaaaaaat ccggacatat taattttaga
     2941 tgaagcaact agtggattag ataccttgtt agaacatgca attatgaatt atctcctcaa
     3001 tttaaaagaa aaaacgatta tttttattgc gcatcattta ccaatagcaa aagcatgtga
     3061 tcaaatttta gttctccatg aagggcattt ggtagaaaaa ggaacgcacg atgaacttcg
     3121 ttttgccgat ggtatctatc aaaaattatg ggaaatctag gagagggaaa caatttatgc
     3181 agaataataa ttggttcgaa cattctagta tctatactaa acaacatcat agcttctacc
     3241 gttgggtgtt ataccctgta attctttttt tatgtattat tggattgttt ttaacctttg
     3301 ctaaaaaaga ggttgttatt cggacaacgg ctcaattgaa ccccgaaaaa atagagaagt
     3361 tacaagtgcc attagaagct aaaataatgg aaaacttcct aaaagaaaat caatttgttc
     3421 ataaggacga tgtgttggtt agattggatt gttctttaat agagaatgaa aaggctcaga
     3481 tagaacaaga aaaccaacgt attactcaac aaataaagat ggctcagcta tttattgaaa
     3541 gtataagtaa aggaaaaaat ttgttttcaa cggatgacag ttttggctac agtaatcaat
     3601 taaagagcat gttgtcagaa aaagaatcac tccgctacgc tttgaagcaa agtgaattaa
     3661 atgatcaaaa gcaattagaa gtatacgaaa agacaaaaag acaactagaa aaacaaattg
     3721 agagttcaga tagtaaatta caagaatggc aacaagtaca ggtagcttgg agtaataatc
     3781 aatcattaaa agatttttca aaagaaatga tggcaaacta tgagaattgg caagaacaac
     3841 taaataatgt ttctgatgat caaaaaaatc aagtgaaact gacaatttca gcaagcataa
     3901 atgaacaaat tgagcaacta aaaaaagaag tagaacagta tcagtcagaa aaagctaaat
     3961 tagttaaacc aactacttct gagaatgaca gaattagtca aacggaaaaa ggaaagcaag
     4021 agctagaaca agcaataaca actgtaaaac aaacagttac agagctaaat gaaaaacaag
     4081 agaagaacca gtcagttatc aaaagtttgg acgatcaact ttcaaaagga atactaaaag
     4141 ctcctgtatc tggaacggtt catttaaatg aagaaacaaa gggacaagca gaactagcca
     4201 aaggaacagt gcttgcagaa atttatccga tccacgaaaa atcaaaaatg aaatttacag
     4261 cacttttacc tgcgaatgaa agtacctata ttaaagaagg gatgaaggtt cattttaaat
     4321 tggatcaaaa aggtggggct ccgattacga tcgacggaac tttagatgaa atttcagaaa
     4381 attctactgc cactgagaaa ggtgtttttt atgcagtgaa aggaacgtta aaaacaactc
     4441 aatcgtttcc gtttcgttat ggattaactg gagagttgtc tttaattgta ggagaaaaaa
     4501 catattggca acaaattgtc gatgtgtttc taaataaaaa ataattattt ttactaagaa
     4561 tataggagga gtttatatga ataaaagaag atggattgct gtgggagtag cgtgcggatt
     4621 attgttacta tccattatcg tcgcgctaat tccaggaaaa gataaagagg aagcatcaaa
     4681 tacaacccta acaggaataa ataagatttt ttacggatct aacgaaatca cagaagaaac
     4741 gttagaagaa ggcgcatcaa ataaaaagat tgtcaaacta tccgtcaatg gagttattgc
     4801 agatacaggt gaaagcaatc tttttagtag ggaacaatat aaccatcaga attttttaac
     4861 acagctaaag aaaattcaag aagacaaagc ggttaaggga gtgttattag aagtaaattc
     4921 acctggggga ggaatatatg aaagtgctga gattgctaaa gaaatggcaa aaattaaaaa
     4981 gctagatatt cctatctata ctgcatttaa aaatacagcg gcaagtggag ggtactacat
     5041 ttctgctggt tcagataaaa tatttgctac ggaagaaaca acaactggat caattggtgt
     5101 cattatttct ggtttaaatt attctggctt attagaaaaa cttggcgtaa ctgatgcgac
     5161 gtataaaagt ggtgcattaa aagatatgat gtcacctcaa cacaaacctt cagaggaaga
     5221 gaataaagtt atacaggaat ttgtgatgag tgcttatgat cgttttgtca atgttgtagc
     5281 aaaaggaaga aatatggata ctaatgcagt gaaagaactt gcggatggaa gaatttatga
     5341 tggtaaccaa gcagtagaaa atgggttggt ggatcaaatt ggttactctg aagatgcatt
     5401 agattcccta aaaaaagaga agaaattaac tgatgcgacg gttatagaat ataaaaatga
     5461 cacaactggc tttgcttctt cttggttagg taataagatt gctgaatggc aagggctaaa
     5521 ggcaactaca tcagatcgtg taatttcagt ttttgaaaaa cttggatttt ctgatactcc
     5581 aaaaccaatg tattactatg gagggctata aaatgaataa gaagagtggc attgaaactt
     5641 tgcctaatta tgtatttgcg ggattttggt tacgattttt tgcttttctt attgatttaa
     5701 tttgtattag catcatcacc catgctacta taggtctctt ttacaaaatc atgggactgg
     5761 aatctgacaa atccattatt actttttatg gtatagcgtc attagctatt tatttaacct
     5821 attttgtact tttgactaag ctgaattcag gacaaacaat tgggaaaatg atttttggga
     5881 taagagtagt gagctttgag gaaaaagagc taagttggca aactatcttt attcgtgagt
     5941 gtatatgtag gtttatatta aaaaattttg tatttcaaat tgggtatttg gtggctgctt
     6001 tcacgcccaa gaaacaacat attggggatt atttttctaa cacgtcagtg gttgttattc
     6061 gttcattaga agctattaac tatggtcaaa aaatttctaa ttctaaaaca cttaatctgg
     6121 agagaattaa atgaataaga gaaaaacaga gtttattttg attttaatta gtggaataac
     6181 agggatttta tgtagtcttt tagcattgat gggtggtatg tttctatctt ctattgattc
     6241 aactacttta aatactacag aactaaccag taaggatata gatatgttag tcaatctaag
     6301 cgggaatgtt gttttatttg gaggaattac cctagttttt tcgataatga ttttcataat
     6361 aggtttttta gtaagaaaaa atcaaaaaac agtggtctat ggtattagtt tactcatttt
     6421 atctattatt ccattttttc ttttaacatt attgtgggta attcctggag ttttaggtat
     6481 tattgcggga ttgatgcttc taataagaaa atcttaatta ggcaatgtgt agacaacgtg
     6541 aaacgattaa tcaattaaaa gctaaatacg ttttgagaaa tgataacttg tagtcgatgg
     6601 aagacatgta gataaaaaaa ctacgtgtct tttatttatt ctaatttttt cgaaaaaaag
     6661 acactctctg attgttgtat taatggaaaa ggggaaagca gcaagtaaat ttagtttttc
     6721 tattaaatat tcttcacttt ttaacctttt atagtactta gatttaatcc tatatgttta
     6781 gagagttcat tggcagcatg attttgcaaa gcttctcgaa ttattgttat attagaaact
     6841 ttactgttca taattatgct tcttttttaa ctcaaagtcc aaagggctac agtggacttt
     6901 gagttaaaaa taaaaagccc tagttatttt gaaaaataaa aaaagaacag cgtaaatgtt
     6961 ttcgaaatgc tttcgcacca acatttacct gttccgtggg tttggcaccc aatgggccgt
     7021 gaggggctcg aacccgcga
//
LOCUS       DAFTHM010000115         7014 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFTHM010000115 DAFTHM010000000
VERSION     DAFTHM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.115"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            230..520
                     /locus_tag="L7C88_002446"
     CDS             230..520
                     /locus_tag="L7C88_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559240.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            533..1558
                     /gene="sppA"
                     /locus_tag="L7C88_002447"
     CDS             533..1558
                     /gene="sppA"
                     /locus_tag="L7C88_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBP9559241.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            1561..2220
                     /locus_tag="L7C88_002448"
     CDS             1561..2220
                     /locus_tag="L7C88_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBP9559242.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            2377..3309
                     /locus_tag="L7C88_002449"
     CDS             2377..3309
                     /locus_tag="L7C88_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559243.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            3463..4752
                     /locus_tag="L7C88_002450"
     CDS             3463..4752
                     /locus_tag="L7C88_002450"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBP9559244.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            4999..6249
                     /gene="clpX"
                     /locus_tag="L7C88_002451"
     CDS             4999..6249
                     /gene="clpX"
                     /locus_tag="L7C88_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBP9559245.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVFNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            6332..6919
                     /locus_tag="L7C88_002452"
     CDS             6332..6919
                     /locus_tag="L7C88_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBP9559246.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
BASE COUNT         2445 a         1145 c         1518 g         1906 t
ORIGIN      
        1 tatcctaaaa ggtataacta tcctcctttt tgttttttat ctggaaacat ttaaaatcat
       61 aaccttttgc gaatgttctt gtcaacaaaa aaagaataaa aaataaattg gtatatatca
      121 aattctttgt caaatgtcct ttttatgtca aaaaataatg ggtttttatc tatcatcttt
      181 ttcaggagtt cggtacaata gaaagtaatc ggatagagga ggagtaaaaa tggattcaaa
      241 aattgagatc atgacactgg gaatgttaaa aaaacaattg tccaaattcg aagcatcagc
      301 tggtgtatca gatgatacga aaatattttt agatactggc tgggatagca tccaagaaat
      361 cgcacctgat gccttggaag ttgctcaagc tcgtgagttt acggtagaag atgaattaac
      421 aaaagagtcg ttttccgggt atgcgcggga agaaaaagca gagcggttcg acacttctga
      481 gcagtcagaa actgtgatcg tcataaaaaa cttgtattag aaaggagaaa gaatgaataa
      541 aagacgttgg gcagcagttc tgattgctgc aggattattt gtggtttcgt tagtttcagc
      601 tagtttgact aagcctcagg aaaacgatca aattgaggga ttgaacagtt ggttatatgg
      661 ggatgaagaa ctagctccaa atgtgttgga agagggagac agtacgcaaa aaatcgtaaa
      721 attatcagta gatggaacga ttgctgcggg agggtcttca ggtttatttg cttctgaagg
      781 ttacaatcat aaaaatttta tggaacaact gaaggcgatt gaagaagatc caacagtcaa
      841 aggtatcttt ttagaagtaa attctcctgg tggcggtgtc tacgaaagtg cggaaatcgc
      901 taagaaattg gatacgattc gtaaagaaca tgatatccca atgtatgtca gcatgaaaaa
      961 catggcagct agcggtggct actatatttc tgctcaagca gataaaatct ttgcaacaga
     1021 agaaacagtg accggctcaa ttggtgtgat catgtcagga ttgaattatt caggacttct
     1081 agaaaaactg ggtgtggaag atacaacagt taaaagcgga gcgttgaaag atatgggttc
     1141 aggaacgcga ccagagacaa aagaagaaga agcggtgctt caagcatata tcgacagcgc
     1201 atatagtcgt tttgtagcaa tcgtcagcga gggacggaat aaatctgaag aagaagtcaa
     1261 aaaaattgct gatggaagga tttatgatgg tgtccaagca aaagaagtag gtttagtcga
     1321 tgaattggga tttcctgaag atgctttaaa agctatacga aaggaacaac agcttgaaga
     1381 tgcggaacta gtagaatatt cttccacgcc atctgggttt gctagtacat ggttaggaag
     1441 taaactagca gaattccagg gattgaagcc ttctgagact agtcagatct tatccgttct
     1501 tgagaatcta gggacagcgg aatcaccaaa agcaatgtat tattacggag gtgagtaagc
     1561 atgtcagagc tttcaaatga aaataaggaa caagaaaaag ataagcaaca gcagcctgct
     1621 gtaggacctg actccaactt ttcccaaaag gtactgagct cttttgaaag agagcctttg
     1681 acgcccgaag aaatcaaaaa gaaacaacgt aaatggaaaa agtatacgga cacaagaaat
     1741 gaaccgccaa aagcaaatga ttttcctaag tatttctatg caggtttttt tatccgaatg
     1801 tttgccttct tggtcgatct tttgtgtatc ggagctatta cgcgtttaac acttggtatt
     1861 gccaaaaatc taggttggct taatttttca gattcttatc tgagtctcta cggattcaca
     1921 gccttactta tttatctagc gtattttatt ttattgacga aattcaatca tggccaaacg
     1981 attgggaaaa tgatctttgg tattcgagtc atcagctttg atgaagaaga acttagctgg
     2041 tcaaccgttt tagttagaga aggtgcttgc cggttcattc taaaatttcc tttgctgatg
     2101 ttagggtatc ttccagcagt ctttaatcag aaaaagcaac atctgggcga ttttttcact
     2161 aatacaagtg ttgttacgat caatctgatc aaagcgttca accaggaagt caacagctga
     2221 tgagcaataa aaagcagtaa cagttgaaag caccttctaa aagtcagatc taaaatctag
     2281 cttttagagg gtgcttcagt tatttttaat tgtcatgctt tttttgtttt gctactattg
     2341 aacatgagct gaatatgagc aagaggagga cactgcgtga agccgattga ttttccagaa
     2401 aaatatgaga atttaatgcg agtggcacaa caagcactag caaaccagca atatcagcag
     2461 gcaaaagaat tatttcaacg agcttacgag ttgaaagaaa gctttgaggc taatagcctg
     2521 cttgtttttt gtctttacga gttggacgag aaaaaagaag cattgaagca agcactcttg
     2581 catgaaaaac agtatcttca aaatgaggag tttgctgaat tttattttga cttgttaatc
     2641 agtacacaag attttttata tgctagaaaa ttgatagcaa gtacagattt ttatgaagct
     2701 ttcgagcagc gggtcattga aaaaatccaa tttgcagaag aattatccgg acaaatggag
     2761 aggcagaaga tcaaggcact ccacaataaa tcggaggaac ttccttcgtt ggaacctgca
     2821 cgtcagcttg cgtctattga tgagatcgaa cagcttcctt atcatgagtt tatccaaaca
     2881 gcgagtaaac ttattgtatc gccagaggtc catattttag caagggcaaa attactggag
     2941 acacttaggc aattgaacga atgccatcct gttttctatt tgacgattga agaaaagtta
     3001 gtcaaagtca taccaaaaga tctgccaaag ccgcagcagc aggcaagtta ccagcaatta
     3061 tgtgtatttt cagatcgtta cgggaatgaa gatgcgctgc ttagttccgt gttaaaagaa
     3121 gaattcacgt tgcaatctgc aattgtttat cctgtctatg atacatacat cgaagacccg
     3181 aagcgctggt ttcaactgac tgtagaggcg tgtacaggaa aaacgatgta tgaaggtaca
     3241 gaagatgaaa aacaagattt tttaaaaaaa agagaaaaaa ttttgcagca aatgatcttc
     3301 ttccattaga ttttatcagt gaaaaagata aaaatgttat gaaaaacaag gattctatcc
     3361 attcaatatg tttacaattt gaaagggtta gtgtactatt taaaggtatg catgaaacgt
     3421 ttttgatgta taaaatgaat ttctaaactc ggagggaatt aaatgactgc aacatttgaa
     3481 aaaaaaggca cgaatgatgg tgttttaaaa tttacgattg cgcaagacga aatccaaaaa
     3541 ggattaacaa ctgcgtttaa taaagtgaaa aaaagcttga acgtacctgg attccgtaaa
     3601 gggaaagttt ctcgtcaagt attcaaccgt atgtacggtg aagaagcttt atatgaagat
     3661 gcattgaatg ctgtattacc agaagcttat gaagctgctg tcaaagaagc tggcatcgat
     3721 cctgtttctc aaccaaaaat cgatgttgaa agcatggaaa aaggtcaaga ctgggtaatc
     3781 actgctgaag taacagtgaa accagaagta aaattaggac aatataaaga tctagttgtt
     3841 gaaaaacaag accgtgaagt aacagatgct gacgtggatg cacgtatcaa acgtgaacaa
     3901 gaagcacaag ctgaattagt tatcaaagaa gatgctgcag ctgaaaatgg cgatacagta
     3961 gtaatcgact tcgaaggctt tgtagatggc gaagcgtttg atggcggaaa aggcgaaaat
     4021 tactcacttg aattaggttc aggctcattc attccaggtt ttgaagatca attagttggt
     4081 cataaatcag gtgaaagtct agatgtaaat gtaactttcc cagaagatta tcaagcagaa
     4141 gatcttgctg gaaaagaagc agtcttcaaa gtgacaatcc atgaagtaaa agcaaaagaa
     4201 gtgcctgaat tagatgacga attcgcaaaa gatgttgatg acgaagtatc aacattagac
     4261 gaattgaaag aaaaatatcg caaagaatta gtagaaacaa aagaaaaagc agcggacgat
     4321 gcaaaagatg aagcagcgat ccgtatggct gttgaaaacg cagaaatcgt tgaattgcca
     4381 cacgtgatgg ttcatgatga agtacatcgt tcaatggacg aattcttgaa caacatgcaa
     4441 cgtcaaggta tctctcctga aatgtactat caattaactg gttctacaga agaagacttg
     4501 cataaacaat tcgaaggtga agcagaaatg cgcacaagaa caaatcttgt gatcgaagca
     4561 attgcagctg ctgaaaatct tcaagcaaca gaagaagaaa tcaatgcaga aatccaagaa
     4621 ttatcagaaa catacaacat gccaatcgaa caaatcaaac gcgtgttgac agaagatatg
     4681 ctggaacatg atgtgacaat gaaaaaagca atcgaattga tcacaggtac agcgacagaa
     4741 gcgaaagaat agaaatcaag taataaatca tttctgaaga agctacttct agaaaattgt
     4801 ttattcgaaa taagggactg tgacacgatt ttgtcacagt tccttatttt ttgttaagag
     4861 taaaaaatgc aaaggtatag gtcagttgat cctttgttaa acactttttc tttttactaa
     4921 actatgttat gatagtaaaa gactgtaaag tctttgatag tttcttgcat actttttgca
     4981 agttaagggg tgaagaccat gtatgacaat ccaagtagca atgagaccgt acgctgttct
     5041 ttttgcggga aaacccaaga agaagtgaaa aagatcgtag ctggtccagg ggtctacatc
     5101 tgtaatgaat gtatcgacct atgtaaagaa atcattgatg aagaatttta tgaagaagct
     5161 gtacgcgaat tcactgaagt ccctaaacca ctagaaattc ttgaagtatt taataactac
     5221 gtgattggac aagatcgcgc aaaacgctcg ttagctgttg ccgtatacaa tcactataaa
     5281 cgtgtcaatc agcaagcaca agaaaacaca gatgatgttg aactgcaaaa aagcaatatc
     5341 tgcttgatcg gacctacagg gtctggtaaa acatttttag cacaaacatt agcaaaaaca
     5401 ttgaatgtac cttttgcaat cgcagatgcg acaagtttga cagaagctgg ttatgtgggg
     5461 gaagatgtag aaaacatttt gcttaaattg cttcaatctg ctgattacaa tgtggaactt
     5521 gcagaaaaag ggatcatcta tattgatgag atcgataaaa ttgcgcgtaa aagcgaaaat
     5581 gtatctatta ctcgtgacgt ttccggcgaa ggtgtccaac aagccttgct gaaaattcta
     5641 gaaggaactg ttgcaagtgt gccacctcag ggcggacgta aacatccaca tcaagaattt
     5701 attcagattg atacgacgaa catattgttc atcgtaggtg gtgcatttga tggcatcgaa
     5761 acgattgtga agaatcgtat gggcgaaaag acgattggat ttggtacaca aaaccaaaaa
     5821 ctttctgaag acgaaagtgt catgcagcat atcattcctg aagatttact aaaattcgga
     5881 ttgatccctg agtttatcgg acgattacct gttatggcag ctttagagaa attgacaaca
     5941 gatgatctgg tacggatctt gactgagccg aaaaatgcgc tagtcaaaca atatcaaaaa
     6001 cttctttctc tagataatac cgaacttgaa ttcgaacctg aagcgttgag agccattgcg
     6061 aaaaaagcaa tcgaacgcaa taccggtgct cgaggacttc gttccatcat tgaagaaatc
     6121 atgatggatg tgatgtttga tatcccttca aatgaaaaca tcgaaaaagt gattatcaca
     6181 aaagaagcag ctgaattgtc tggtgagcca acagtaatct ataaagattc agagaaaaaa
     6241 gcgggttgat gaaaagaggc tgccgtaaaa gtcattttgg cttttgcgac agccgcttgc
     6301 tttattcatc accttgttaa ggagagagac catgaaagtc catcaagctg aaattatcat
     6361 aagtgcagtg gcaccaaaac aatatccaga tacacaattg ccagaaatag ctctggcagg
     6421 acgatcaaat gtagggaaat cttcttttat caacacattg attgatcgaa agaatttagc
     6481 ccgtacttcc ggtaagccag gaaagaccca gacattgaat ttttatttga tcgagaacgc
     6541 attacatttt gtcgatgttc cgggatatgg gtatgcaaaa gtatccaaaa ctgagcgagc
     6601 aaaatgggga aagatgatcg agacatattt aacgactaga gaccagctac gtgcggtcgt
     6661 ttctttagta gatttgcgtc ataagccttc tcaagaagat atccagatgt atcaattttt
     6721 gaagtattat gatatccctg taattgttgt tgccactaag gcagataaga tccctcgtgg
     6781 taaatggaac aagcatgaga gcgaaatcaa aaaagcgttg gattttgatc gcaatgacac
     6841 gtttattctc ttttcttccg ttacaaaaca gggaaaagaa gaagcgtggg cagcaatcga
     6901 acaagcaatt gaatcataaa aagaataaaa aagacttacc agtcaaactc tttcataaaa
     6961 gtttggctgg taagtctttt tttgagctta acttactttt gtttcttgtc tttt
//
LOCUS       DAFTHM010000116         6910 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFTHM010000116 DAFTHM010000000
VERSION     DAFTHM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.116"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..2946)
                     /locus_tag="L7C88_002453"
     CDS             complement(<1..2946)
                     /locus_tag="L7C88_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBP9559247.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWSNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIERENPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIIQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGVSSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHA
                     FSNEWFVSEK"
     gene            complement(2960..4177)
                     /locus_tag="L7C88_002454"
     CDS             complement(2960..4177)
                     /locus_tag="L7C88_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBP9559248.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(4167..5762)
                     /locus_tag="L7C88_002455"
     CDS             complement(4167..5762)
                     /locus_tag="L7C88_002455"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBP9559249.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYSISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            5887..6672
                     /locus_tag="L7C88_002456"
     CDS             5887..6672
                     /locus_tag="L7C88_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HBP9559250.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPALKKPLKTFGEKD
                     AALTTRVAANANIDDQKVLNDYLRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCAG
                     SVYRAVDFCYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSP
                     IPNWKALIEMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
BASE COUNT         2023 a         1405 c         1147 g         2335 t
ORIGIN      
        1 tttctcagaa acaaaccact cattggaaaa ggcatgaatc aaattatcac ttgcttgtgt
       61 aaaatagcga cgtttaatga caaagatatc ttcattacta tctaaagtcc ccacatcaaa
      121 tgcatttaaa atttgtcggt aaacttcttt gactccttct gttttattca atttagccaa
      181 agctttttca atttcttctc gtgcatctga actattcgca gcataagttc ctagtaattg
      241 atcaatataa gtagaatcaa tatcatacaa cttagtggta ttttcactat aaaattcgat
      301 cgttgaaaaa tcttctccct ctttttctgg ttcttcctcc atcaatgaac ccttcacggt
      361 ctcgtacacg ccaatttgtt cttccaaaag ttgaatttga ttgttcaaag ttgaagattg
      421 caccatgtca tcattgtaat catcataagt cactaacgat tcatacgcac gattcaattc
      481 ttgaaatgct ttgacgtact cgatacggat ttcaagtggc gtatgttcat caatggattc
      541 catggatgaa acctctttta acttaccata tgcttgcttg aatctttttt tggattcttg
      601 gtaacttgga taaatcaaac ccgattcttc tttagcttct gaatacagtt ttgtcgcatc
      661 ctcgacattc ttctccattg tcgctggctt tcggaaagta acaattagtc cttttgtttt
      721 ttcaggatac gtacggttcg tacgtgaaaa ggcttggatc aatcctgcat actctagatt
      781 acgatccaca aatagggttt gaatcgtagg ggcgtcaaaa cctgtcaata gacgatccac
      841 tacgattact aaatcgattt gtttcccaaa ttgtttgaat tccgctcttt ttcgtgccaa
      901 acgattattg atgtctccgt tataacgctc aatgtctgct agtgaccagg cagtatcata
      961 atactgatta tattcctcaa taattttttg catttcttct tgttgggcac ttgaatctcg
     1021 gctattttct tctaatgaat aggtaatagc gattcgtggg aaatcaggat cctccatcgt
     1081 tcgtccttca cggataggct gattgggaaa ctcttttatt aaccaatcag attctttcgt
     1141 catctctttg atggcccgat aatacttttt ggccatatca atggaactcg tggttaagat
     1201 cgcagacttc gttggacggc catttcgaaa atcaaatttt gtataggcat tgtctggacg
     1261 gaacatttta tgaatgactt tttggatatg ttcctctgct tcaaaaacag tagggtccaa
     1321 ataactttct tttttgacag actccatttg atcgatcata cgattgatct gttccggtga
     1381 atactctgca tatgtttcta cttcttttaa tttccgatag attttattct ctaatgaagt
     1441 cggctccacg gtgttttcat gctctacttg aaatcctaaa accgagccat cttctaatgc
     1501 attcttgatg gtataggtgt gcaagacctc tccatactga tcatgggtcg tacgtgccaa
     1561 ttgccctttg gcttgtttcc gattctcagg gaaaatcggt gtacctgtaa agccaaacca
     1621 agtggatttc ggaaacattt ttttgatttc ttccatattt tcagcactta acgctcgatg
     1681 acactcatca actacaaaca cgatatgttg ccccattaat ttttggaagc gattggttcc
     1741 ttttttctct tcctgtttct ttgcatattt caacgccgca tctagttttt gacgggttgt
     1801 aatgatcaca acattcgcat tggcatctgc caacagagtt tcacttaact ctttggcact
     1861 tcctgttccc acgatcaagc tattcgcttt ggcattacca gaagaaaccc cagtattaaa
     1921 ctccgaagca aatttcgtaa actctgtggt ggtctgatta tctaaatctt tgcggtccac
     1981 taacatgatc gttcgatcga tccccgattt tcgtgctaaa agcttagtag atacaaaact
     2041 agtcaacgtc tttcctgaac cagtcgcatg ccacacatac cctgattgat gtttatttgc
     2101 ggcaataaac aaggcttgaa tcgcatgcac ttgataagga tgtaacacca tgagggtttt
     2161 attgtcttga tcttcactga caatcgtata atccgcaatc aagcgatggg catctgggat
     2221 atttagcact tgtttgcaaa actcatataa gttttctacc tttttattat ctttcgttcg
     2281 ccaactaaat aaaaacttag gatgcaaatc cttcggtaag gcatttgcaa aataccgagt
     2341 cgtttgttca ttggaaacca caaacaactg taaggtcgaa aagatattgt tccgaaacat
     2401 gccttcttca gcatattttt tgatttgatt aaacgcctga taaaaaccat cttttgcagt
     2461 tacttgtttt agctcgattt ggataatcgg taagccattg atcaataagg tgacgtcaaa
     2521 acgtcgatcc cgcgcttcta tgttacttcc acgttttgca atttgatgga ccacttcata
     2581 agtagagatt cctccaccaa tgtcttgatt ggaataaagg ataagtgaga cagaacccaa
     2641 ttgcggattt tcccgttcaa tcgtgatccg agccatccca ttttcacctt ttaaccattt
     2701 cgcagcatca aatggggttt tcgtccgtag caataattcg gttttgatcg tttcaaactc
     2761 tttatcggtc aaaggagaat cattcagttc tgcttgatta tttgagatga ttttttgacg
     2821 taaattgctc caaagatctt cttctgattt tagatccgga cgatacgtcc actgattatg
     2881 tccttccccg aggacacgaa tcaactgttc ttcgacttcc gcttcctcac ggtgactaat
     2941 tttcattctt cttccctccc taaacaaaca tcttttgcaa gaagcctttt ttcgtttcct
     3001 tcagcaaatc taacttacgt tgatgaagag cgatcgtatc atctagctgc ttgaagaagg
     3061 caccaatttt ttgttgttca tttatatccg gtggaaactg aaatgtcctt tgttctatac
     3121 cacctttagt cacatgtacc attgtcgttc cgttagttga ttctttaatt ttctctttat
     3181 cagtcaatag ccaagtatat agatactgtt tgtccaattc cttagataaa aatttaagtt
     3241 tccaaatatg ataatggtag attacacgtt cttcattcca catttcagga ccgaagcttg
     3301 ttgcccataa atataagaga tctcctttat tagcatactt gtcttcctct aattctaagt
     3361 ttgaataata ccatctatca ttagtattaa aattacctac tcttaaaacc ctatattttc
     3421 cagaatcaag taattcttgt tgtttaaaag ctctaccatt caaaaaaact accacttccc
     3481 ccaacttccg ctcttcccaa tctcccgtaa atcctggaaa acgaacttct ggcacttttg
     3541 ctccgttttt agggaacatt ttttgtaaga atcctttttt cgtttccttc agcaaatcta
     3601 attcgtgctg gtgaagcatg atggtgtgat caagttgttt gaaaaatgaa ccgatcttga
     3661 tctgttcgtc ataagttgga agtgagatag gtgtcttttt accactatca attgtatagg
     3721 ttccgacggt tccaatgcct gcaacgtcac ggatatactt ctgaattttg ttatttatga
     3781 acgagtagta aaagaagttt ccgtcaattt tatgctcatt cttgaaccaa atgatgtttc
     3841 catccttaaa gtaaattggg ttatcatcag tgattaataa ggggacacct attgatccga
     3901 caccagttac aagcaagtct ccttgagaaa ctttacctga atttttcgaa tattcattat
     3961 atttttcttc tgaaatgtaa agataatcgg atggttcctc attttttgca gctgagacaa
     4021 tatcacgagc acgtaaaaat ctaatacctg agttagtcca atctgattga tgaattcgct
     4081 tcacagaagt aacatccatc atatctccta acttacgctc ttcccaatct tccgtaaaac
     4141 caggaaaccg gatttctggt cgtgtatcat tgctcatgtt tgaacacctc cagcgcacct
     4201 tgtaaccacg cttcattttc aggtgttgtt tgcagggaag agatagcttc taaaagttct
     4261 ttttctagca cttgctgttc ttgtcgtatc ttcttgatgt catttccgac atgaaccata
     4321 tcaattggtt cttcttcttc gaaagtatcg acatagcgtg ggatatttaa gttatagtca
     4381 ttttctttga tttcatcaaa ggttgccaaa tgagcgtatt tctcgacatc ttttctttca
     4441 gcgtaggttt cgaggatttt ttgaatgttt tcttccgata atttattctg atttttccct
     4501 ttaacaaatt cacgactagc atcaatgaat aatacatctc gagtttgacg attcttcttc
     4561 aatacaatca ccgtcgttgg aatcgatgta ccaaagaaca agttcgcagg cataccgatc
     4621 acagcataaa tactgccgtc ttctaataat ttttgacgaa tgaccccttc tgcagcacca
     4681 cggaataaaa ccccgtgtgg caagacgata gccatagtcc ctgtttcctt caaatgatag
     4741 aaaccatgaa gaagaaacgc aaaatctgct ttggattttg gcgctaattt cccgtagcga
     4801 ttaaaccgag aatcatctaa gaaggtcgta tctgctgacc aattagccga ataaggtgga
     4861 ttcatcacta ctgcatcaaa tgtgtaaggt tcatctgttg gccagtcctt attcaacgta
     4921 tccccattgc ggagattcat ttcttcggca tctaccccat gtaaaatcaa gttcattttt
     4981 gctagattgt atgtcgttgt atttagttct tgcccatgat atttaacgtt atctggatga
     5041 gttaagtagt tacgtacatt taacatcaag gaacctgaac ccatggttgg gtcaaagaca
     5101 ctaaagaatc gtcgttcttt ttgatccaac gtcacgattt gtgccatcat atcagaaacc
     5161 atatgaggcg tgtaaaattc tccggctttc ttccctgctt ctgaagcaaa ttgactgatc
     5221 agaaattcat acgcatcccc gatcacatcc ccatcgtgac ctaaaacttc cacgtcattc
     5281 aatttcttga taacttcggt aatcgtcaca tttcgttgtt gctcatctgt tcctagtttt
     5341 tttgattgga gatccacatc atcaaataac ccattaaatt gattgtaggt agatgccaat
     5401 tgcacaaagg ctttgtttag atcgttcaat tggaacgttg cttgttttgc ttgatccgct
     5461 aagacgttga aaagatactc tggtgagatc gaatacccca aaatatcaac gattgtggca
     5521 atcaggtctt cttttgattc ttcatctgaa agtaattcac gatacaacat tgtttgtttg
     5581 cttactgtgt catattcctc taaggattca tctgctaaaa gaaccacttg ttccaacaaa
     5641 cggtcggata aatatttata gaaaatcagt cccaataaat aatttttata ttctgacgca
     5701 tccattttac tacggagatt atctgccgca ctaaataatt tttgatttaa ttctgcaccc
     5761 aaaaagatac actcctatct cttatttaaa gttgctatat accctcttat tttagcatac
     5821 tcccttttag aaaaagcaaa aaaaaaagaa aaaatcttat tcttgataac aagctacgtg
     5881 acgtatatgc ctaacaaaaa tagaactttt gaatcaatct taaatgaagg tttaaccaca
     5941 gaaccggcat ccattatttt tgatgaagtt atcgatgacg ttgaagatag taagtatcat
     6001 aaaaatttaa aagaactttt ttattttgca ctcaacaatg gaccaagttt gttcactggt
     6061 atatcagtac ctgatagtga taatccatta attatggcaa aaatttactt aacaaaatgg
     6121 tgtaataaat acatcaggga taggaataac ccagcattaa aaaaacctct taaaacattt
     6181 ggcgaaaaag atgctgcttt aactactaga gtagcagcaa atgctaatat tgatgatcaa
     6241 aaagtattga atgactactt gcgtggacat tttttatata tgagcgctga gaacatgaac
     6301 ggaagtattt tagaggaata tttagccgaa gtgttagaac ctgaaggttg gatttggtgc
     6361 gccggctctg tatatcgagc tgttgatttc tgttatttag gaacctcacc aattctttta
     6421 caagtgaaaa ataaatacaa tacagaaagc agttcgagtt cagctataag agtaggaaca
     6481 acaattagaa aatggaatcg tttaaataag tcgacaaaaa tttctggttt ggatagccct
     6541 atccccaatt ggaaagcatt aatagaaatg actgaagcta gtaaggaact ggcagctaag
     6601 ttaactgaaa atagttattt agcttatatt aatgaaaaat ccacacgaga attatggaca
     6661 ctcgatgact aacaatatcc ttattagtat ctatccacga tacatggaaa aaattataaa
     6721 caaacaaaaa aactttgaat ttagaaattt ctatcttacc tcagatcctt ataatatctt
     6781 ttggatttac gaaacaatcc ccaccaaagc tttaaagtat aaattgattg taaaaaatcc
     6841 aattactaaa cttaagaaaa atcaacacta ctttttagga gacgatgagt ttgaacaatt
     6901 agtttaaaag
//
LOCUS       DAFTHM010000117         6909 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFTHM010000117 DAFTHM010000000
VERSION     DAFTHM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.117"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            179..1114
                     /locus_tag="L7C88_002457"
     CDS             179..1114
                     /locus_tag="L7C88_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBP9559251.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            complement(1199..2209)
                     /gene="gap"
                     /locus_tag="L7C88_002458"
     CDS             complement(1199..2209)
                     /gene="gap"
                     /locus_tag="L7C88_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBP9559252.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            2503..3810
                     /gene="obgE"
                     /locus_tag="L7C88_002459"
     CDS             2503..3810
                     /gene="obgE"
                     /locus_tag="L7C88_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBP9559253.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            4031..4618
                     /locus_tag="L7C88_002460"
     CDS             4031..4618
                     /locus_tag="L7C88_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBP9559254.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            4795..5736
                     /locus_tag="L7C88_002461"
     CDS             4795..5736
                     /locus_tag="L7C88_002461"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBP9559255.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            5733..6521
                     /locus_tag="L7C88_002462"
     CDS             5733..6521
                     /locus_tag="L7C88_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBP9559256.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            6522..>6909
                     /locus_tag="L7C88_002463"
     CDS             6522..>6909
                     /locus_tag="L7C88_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBP9559257.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLK"
BASE COUNT         2231 a         1193 c         1567 g         1918 t
ORIGIN      
        1 tacactcctt tgttttcttt cgtcggaaat acaatttgag tgtaccataa atgccttttt
       61 atttttctaa cttaatttta caattcgcgg gttataaaaa tgaacattgc atagtagaga
      121 ttctttgatt atactaattc aaggttatat gaaaaaagag aaatgagatg gatgatttat
      181 gaaactttgg atgaaaatcc ttttaggcgt cgctttagct ctgattgttg cgttagtgtt
      241 tgcagggaat tatttttata attatgctgt tgtgccttct gagaaagact ttttagacga
      301 agatacacct ggtacaacac agacatccaa agaaacggat gcacataaat ggtttagttc
      361 aaaagaaaac cgaagcgatt ggaccatcac ttcaaaagac ggtctgaaat tatcagcgat
      421 ttatcttcct gctgaaacga aaagtgaaaa aacagctctt gtggctcatg gctatatggg
      481 aaacgctgaa acgatgacca attacgcaaa gatgtttcat gatatgggtt acaatgtcct
      541 tgttcctgat gcaagaggac atggaaaaag cgaaggggat tacattggat ttggatggcc
      601 agagcgtaaa gactatgtac agtggataaa caaagtgcta gaaaacaatg gaaaatcgca
      661 agaaatcgtt ctatacggtg tcagcatggg agcagcaaca gttatgatga ctagcggaga
      721 aaaactacca gataatgtga aagcaatcat tgaagattgc ggttattctt ccgttcatga
      781 tgagcttgct tatcagctag acgatatgtt tagtcttcca gcatttccgc ttatgcaagt
      841 aacgagtcta gtgacaaaag tccgtgctgg ctactttttc ggtgaagcaa atgcagtgga
      901 acaattgaag aaaaaccagc gcccaatgct ctttatacat ggagacgaag atacatttgt
      961 accatttgaa atgttagata aggtctatcg tgcaacgaag ggaccaaaag aaaagtatgt
     1021 tgtaaaagga gccgagcatg cggaagcata caagacagat cctgaaaaat atcagcaagt
     1081 agtccaacaa tttttaagcc aatatgttca ttgaacgagt ttaaaagtag gggatgaaaa
     1141 gaaagaagcc tttgactgga tccagtcaaa ggcttctttt atcgattgat ctatcaaatt
     1201 acaagttagc gaatttttct agtaagcgaa tcatttggca agtaaatcca tactcattgt
     1261 cataccatgc aacagtttta acaagttgga aatcaccagc agttgttact tctgtttgcg
     1321 ttgggtcaaa gatcgaacct tgagttgttc caatgacatc gctagaaacg atttgacggt
     1381 catcataccc gaatgaagga ttgtcaactg tgtgtttttt gattgcttcg tttacttgat
     1441 cagcagttac ttttgttttc aatactgaaa ccaattcagt taatgaacca tcaacgactg
     1501 gaacacgttg tgcgtgtcct tgtaattttc cttgtagctc agggataact aagccgattg
     1561 ctttcgcagc accagtagaa tgtgggatag tattgtcagc agctgaacga gcagcacgca
     1621 aattaccgcc ttttacaggt ccatctaaga gcatttgtgt ggaagtgtag gcatgaactg
     1681 ttgtcattgt accaacttcg atcccaaatt cattatttaa gaaataagcc ataggtgcta
     1741 aacagtttgt tgtacatgaa cctgctgaga tgattttgtc gttttcatct aatgtatcat
     1801 cattgacgtt atagacgatg gttttcatag caccagctgg ggcagaaata actactcgtt
     1861 tgacaccagc atctaaatgc gcttttgctt tttcttcaga tgtataaaaa ccagtacatt
     1921 ctagtacgat atctacaccg ttttcttttg cccaagggat tttgcttgcg tcgggttctg
     1981 cataaacacg agttgcttcg ccatccacta cgattgagtc ttctgttgca gtaactgtgc
     2041 caggataagt accatgagta gagtcaaatt gcaataattg tgctaacata gttggacttg
     2101 ttaagtcgtt gattgctact acttcaatat catctgagac ttctttgatg cggcggaaag
     2161 ccagacggcc aatacgccca aatccgttaa tacctacttt tactgtcata tcaaaagttc
     2221 ctcctttatt aggggtgctg tgaaacggca tcctcaatta atacaattaa tacactgtta
     2281 ttctgctacg caaagaatat tttgtcaaaa aattatactt ggtagcagaa aaaaggttgg
     2341 aaaccttacc aaatgataaa aaaagaagaa ggtaaacaat ctttttgctg aaatgataga
     2401 caaaatcaga tttcaccgat aaaataagta agacttttgt ttattgtgga aattcaggca
     2461 gtcaaataaa taaatgaata ataggaggac ttaattatgt ccatgttttt agatcaagta
     2521 acgatcgatg tgaaagctgg caagggcgga gacggaatgg ttgcatttcg tcgcgaaaaa
     2581 tacgttcctg acggcggacc ggctggcgga gacggtggtc gtggcggcga tgtcatcttg
     2641 atcgtcgatg aagggttacg tacattgatg gattttcggt tcaatcgcca tttcaaagcg
     2701 cagccaggtg aaaatgggat gagtaaaggg atgcacggtc gtggttcaga agatacctat
     2761 gttaaagtac cacaaggaac cactgtccga gatgcggaga ctggtgctct tttaggagat
     2821 ttaattgaaa atggtcaaac actagttgtg gcaaaaggtg gacgcggtgg acgagggaat
     2881 atccgttttg cctctcctcg gaatcctgca ccggaaattg ctgaaaacgg tgaaccagga
     2941 caagagcgaa aaatcgaact agaattgaaa gtattggcag acgttggact tgtaggtttt
     3001 ccatctgtcg ggaaatcgac tttactatcc gttatttcat ctgctcgtcc aaaaatcggc
     3061 gcttatcatt tcacgacgct cgtacctaat ctaggaatgg ttactacaag tgatggcaga
     3121 agttttgccg cagcagactt gccaggcttg attgaaggag cttcgcaagg tgttgggctg
     3181 ggtacacaat tccttcgtca tatcgaaaga acacgagtaa ttttacatgt gatcgatatg
     3241 agtgggatgg aaggacgaga tccttatgaa gactatcttg ccatcaacaa agaattatct
     3301 acttataact tacgcttgct agagcgtccg caaatcatcg tggcaaacaa aatggatatg
     3361 ccggatgcac cggaaaatct agtgaaattc aaagaacagc tgaacaagga aaaagaagat
     3421 gaatttgctg atgacatccc agtatttcca atttctggag tgactcgaca aggattggac
     3481 gcgttattga atgctacagc agatttgtta gaagtaacgc cagaattccc attgtacgaa
     3541 gaagaactgg aagaagaaac tgtacactat ggattcaatc cagaaggtcc tgagttccaa
     3601 atcgatcgtg attcagatgc aacgtggatc ttatctggtg agaagatcga aaaattattc
     3661 caaatgacga atttcgatca tgatgaaaca gtgatgcgtt ttgctcgtca attacgtggt
     3721 atgggtgtgg atgaagctct tcgggcacgc ggtgcgaaag atggcgacct tgtacgtatc
     3781 ggtgagtttg aatttgaatt tgtcgaatag gcaagcaaat aaaaacaaat accaaaaaat
     3841 atagattcag atttaaggga ggttgtgaca gaagtgatca gcttcaagaa cgccgtttat
     3901 tcggaaaaag gagctgtgat acgacttttg tcacagccct attttattgg aaaaaaagag
     3961 tgcttttctt ttcttatttt tcaattaaag gtaaaataaa taacaagaag gtatgaaagg
     4021 ggcgttttta atgagcaaac gagtaatcat tttaaatttt caagtagaaa gccaggcata
     4081 tcaggcattt tcagaaatca aaaagttaca tgctgttcgt tcgattaaag gagaacagat
     4141 ggcagttgtc agccatgatc ctaatgggac acatcaattc aaaatagaag attttatcga
     4201 ctttaccggt aataacaaat cttctacggg tggattaatc ggaatgttgg ttggtgtatt
     4261 aggtggtccg ctagggattt tattaggatg gtttgccgga ggaatgatcg gtgcgacaca
     4321 agatgccaaa gaaataaaag atgcccagac cgtgttcgac tttgtaggaa ataaaatcgg
     4381 tgaaggagct acaggactga tcttgattgc tgatgaagag gacaatcgcc cactgaatca
     4441 attggtaatg atggaattag gcggagaaat tactcgcttg gattatgaag atgtcgaaaa
     4501 agatgtgcat gatgcgaaag aagctgaaaa tcatgcgaaa gaagctgcac aaaagacttg
     4561 gaaggacaaa catccgcaaa cttccaacga caatgaaagt tctggatctt caaattaata
     4621 aaaaacagca gaggatctca aacgggttcg ctgctgtttt tatagtaatt ttcaaagaaa
     4681 acgctatcgc tttagaacgt tatttttaat ttgaacccat tctcgactta cggttgatta
     4741 tcccttcttt ttaccctaaa attaaagagg aacttaaaga aagtcaggta gattatggaa
     4801 ttacaatttt taggaacagg tgcaggtgtt cctgcaaaac atagaaatgt gacaagtata
     4861 gcattgaaac ttttagacga gcgcaatgaa gtttggttgt tcgactgtgg cgaaggcacg
     4921 caaatgcaga ttttgcgaac gactattcgt ccgagaaaaa tcggtaaaat tttcattaca
     4981 catttacacg gcgatcatat ttttggactt cccgggctca tcagcagccg gtcatttcaa
     5041 ggtggggata cgccattaga gatttacggg ccaaaaggga tagaggaata cataaaagtc
     5101 tctttaggta tttcgcaaac gcgtttaagt tatccgctga aattcattga gctaaatgaa
     5161 acagccccga tttttactga tcagcaattt tctgtttata caaaaaaact aaatcatggg
     5221 atcgacagtt ttggttatcg tgtggttgaa catgatcata aaggagaatt gcaggtggat
     5281 cgtctaaaag aattaggtat tccagctgga ccactgtacg gcaaactgaa gcaaggtgaa
     5341 acgatccaac tagaagatgg gcggacgatc aatggaaaag atttcgtagg tccagataaa
     5401 aaaggacgaa tcgtgactat tttaggcgat acgagaaaaa cacataattc cgttgtgctt
     5461 gcggaaaata gcgatattct ggtacatgaa agcacattta ataaagatga agcaagaatg
     5521 gcgcacaact atttccattc cacgactcat caagctgctg aagttgcaaa agaagcgcag
     5581 gcaaaacggc tgctacttac tcatatcagt gcgagatatt taggaaaagc agctttagag
     5641 cttgaaaaag aagcacaaga agtgtttgaa aacacgacga ttatgaaaga ttttgatagc
     5701 attgagattc catttcgcga ggaggaagag gcatgaattt agaagataaa gttgttttag
     5761 taacaggtag ttcaggcggt ctgggcgcac aaatctgtta tgaagcagca aagcaaggag
     5821 caatcgttat aagttgcgca cgaagaatgg catttgtaga aggtgtcaga gacgagtgca
     5881 gacgcttgag cggcaaagag gcttatgctt tcaaggtaga cgtcagcaat cctgaaagcg
     5941 tggacgaatt atatgaaaag gtgatggaag aagtcgggcg cgtcgatatt ctggtaaaca
     6001 atgcgggttt tgggattttc gaagacttcc ttacattcga ccttggaaaa gcatacgata
     6061 tgtttgaagt caacatctta ggaatgatgg ttttgacaca aaaatttgcg atcgatatgg
     6121 cagaaagaag acaaggtcat atcattaata tcgcctctat ggctggaaaa atggcaactg
     6181 caaaatcaac ggtttattct gccacgaaat ttgcagtcct tggcttctcc aacgctttgc
     6241 gattagaatt gaaaccactt ggcgtagctg ttacgacagt gaatccaggt ccaatcgaga
     6301 caaatttctt cgataaggct gatccaagcg gaagctattt ggaaaaagtc ggacaaatcg
     6361 ttttagaacc tgccaagttg gcaaaaatga tcgtccgcaa tatgagacat ccaaaacggg
     6421 aaatcaatca accgtttatt ttagaagttg catcaaaatt ttatacgctg tttccaacga
     6481 ttggtgatta tttagccagc ggaattttta acaaaaagta ggtgaaggaa ttgaaaaagc
     6541 aaagcaatgt gattcttgga tttgttttag ttttgattat tgttcttttt gctgtattga
     6601 acaataaaaa tgttcctgta agttttggct tcacttcctt ttctgcgcca ttgatcttag
     6661 tgatcatcgg ttctgcgctg attggtgcac tgattgtatt tttgactgct tcggcaacac
     6721 tatggcagca aaaaaagcaa atcaaacagc tgactcagga aatgtcagaa tatcaaacag
     6781 aacttcaaaa gaaaattgaa gaagcaaaag aagaacagca acgcgagttt agaaacgaac
     6841 gtgcggagtt ggaagctgct tatcaggcgg agttacaagc gaaaaccgca caaatcagtc
     6901 aattgaaag
//
LOCUS       DAFTHM010000118         6826 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFTHM010000118 DAFTHM010000000
VERSION     DAFTHM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.118"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            630..1163
                     /locus_tag="L7C88_002464"
     CDS             630..1163
                     /locus_tag="L7C88_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBP9559258.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(1653..2177)
                     /locus_tag="L7C88_002465"
     CDS             complement(1653..2177)
                     /locus_tag="L7C88_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9559259.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(2170..2643)
                     /gene="tsaE"
                     /locus_tag="L7C88_002466"
     CDS             complement(2170..2643)
                     /gene="tsaE"
                     /locus_tag="L7C88_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBP9559260.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(2766..3746)
                     /gene="pta"
                     /locus_tag="L7C88_002467"
     CDS             complement(2766..3746)
                     /gene="pta"
                     /locus_tag="L7C88_002467"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBP9559261.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(3899..4579)
                     /locus_tag="L7C88_002468"
     CDS             complement(3899..4579)
                     /locus_tag="L7C88_002468"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBP9559262.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            4705..5574
                     /locus_tag="L7C88_002469"
     CDS             4705..5574
                     /locus_tag="L7C88_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBP9559263.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            5600..6115
                     /locus_tag="L7C88_002470"
     CDS             5600..6115
                     /locus_tag="L7C88_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559264.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(6162..6755)
                     /locus_tag="L7C88_002471"
     CDS             complement(6162..6755)
                     /locus_tag="L7C88_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9559265.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
BASE COUNT         1995 a         1410 c         1249 g         2172 t
ORIGIN      
        1 ccgtttatta agaggttgtg aaaaagctgc actgcatcaa gtaataagaa cagccaaaca
       61 aaaatagttc ctcatatttt tcgtttggtt gggcttatta ccgcagatgc aagcttttga
      121 acaccgttta ttaagaggtt gtgaaaaagc tgcactgcat caagtaataa gaacagccaa
      181 acaaaaatag ttcctcatat ttttcgtttg gttggactta ttaccgcaga tgcaagcttt
      241 tgaacaccgt ttattgagaa gttgtgaaat cagcgtcctg acctgagtat tagagaaaca
      301 aatggcaaaa tagttcctca tattttgcta ttttttgagc taataccgag ggtcagctga
      361 ttgaacaccg tttagtggag aagttgtgaa aaagtcgcct actttcgagt cgtaagaaat
      421 ttttttgaaa atggttcctc acaactttgc ataaatttga cttaataccg agaagtcatg
      481 atccccatct aactccaaat cacaaggaat gagttcaaaa actagctttt ctcaacaaat
      541 attacataaa aaattctatg ttttttgtta aatttatttg cttttttcaa aagtatgtta
      601 cagtaatttc ccaaggaggt tttacagaaa tgaattttgt tgccatggat tttgaaactg
      661 ccaatcatca gccttatagt gcttgttctc ttgcgctagt catggtaaaa aatagccaga
      721 tcgttgatga attctataca ttgatacagc ctgagactcc ttttttctgg cgaaatgtcc
      781 aaattcacgg aatccatcaa gaagacgtac gcaatgcgcc gaaattccca gaagtctggc
      841 aaactatcca accatatttt caaaaaaatc gtttagtcgt tgcacataat gctgcttttg
      901 atacaaaggt cttagcggga tgcttagatt attatcatct tgaacagcct aattatcttt
      961 ctttatgtac agtgaaaagt agccgtcgcc tgtttcctga atttccaaat catcgattga
     1021 acactgtgtg cgaaaatttg aacatccaat tagatcatca ccatgatgca ttggaagata
     1081 gtcgtgcatg tgcggaaatc ctgctttatc aagaaaaaaa attcgggaca gatccattga
     1141 aaaaacttgt gactataaag taaaagaata cttatgaaac acacaaagag gtcgtgagcc
     1201 tgccgtttca ctccgagtca caaggagcaa tttcaaaaaa tagcttctca tgtttattaa
     1261 atattgtgac tggtgaccga ggagctggca ggagaacacc gtttattgga gaggttgtga
     1321 aaaagctgtt ctgcatcaag taataagaac agccaaacaa aaatagcttc tcatattttt
     1381 catttggttg gacttattac cgcagatgca agcttttgga caccgtttac caagaggttg
     1441 tgaaatcagc gttttgacct gagtattaga gaaacaaacg gcaaaatagt tcctcatatt
     1501 ttgccgtttt ttgagctaat accgaaggtc agctgattga acaccgttta ttcaaaaaaa
     1561 atggactgcg acacgacttt tgtcacagtc ccttcgtgtg tttttctgcc ttctcaaaag
     1621 gatgacagtt tctcactctt ttcctatttc ttctattcaa tcaaataact cattttatat
     1681 acatctaaaa attcacctag atctgttctt gcccctctag gcatgaccgc ttcgatttgg
     1741 aagcccattt ttcggtaaag gtgtacggct ctttcattac gaacttgaac gtcaagctcc
     1801 aatcgaaaaa gtacacccat ttccttcgcc caactgatga tttcttctag cataagagtg
     1861 cctagtccca ttccccaata ttcctgcaga atactgatac cgacttctcc cacgtgagac
     1921 aaacgaaatt gactgtctgc cttgacagat gctgttccaa taatcgtccc ttcatagatt
     1981 gcaagcagca ataaattatt attgctttcg tatatataat ccaactcttc ttctaaggtt
     2041 tctggtggta acaggagttc tgcttcatcc aaaactaaaa attctgtctc cttattaact
     2101 tgtcccatca tcaaaagaat gtcttttgca tctcctggca ctgcttcccg caagatgatc
     2161 ccaacttctt cactcatgat tttcagccca tttttctaga attcgctgtt tgaaggtttc
     2221 actttgctcc ccgtatgaga ttagtttcac ataccgcttt tctaaatctg tatcactttt
     2281 ttctaaaatc agttccaaat aatcctccgg cagtgcttct tctaatagat ttccccattc
     2341 aacaacggaa agcccatcac cttcaaaata ttcatctaac cctaaatctg ctccgctagc
     2401 tgctacccga taaatatcca tatgatacaa cggaatccga ccttgactat attctctaat
     2461 aatcgtgtat gtcggacttt tgatcatttg cgttatccct aatccttggg caattccttt
     2521 cgtcaacgtt gttttacccg cacctagatc accagtcaat atcagattgt cacctggcat
     2581 tgcggaatga ccaattgcct ctgcgaattg ttctgtcatt gttaatcctg atagttcgat
     2641 catttttcat cttctcccgc tcttctttct ttttgccagt atatcgcgta atgaagtttt
     2701 tttaaagaaa aaatgaacta gtcaagaaca gcagctgctg tttttggcta gttcgcgtgt
     2761 atttgttaat caatcaatgt ttgtgctgct gtgataatcg ataatttata tacatcttct
     2821 tcatttgctc cacgagacaa atcagaaacc ggtttgttca agccttgtag aattggtccg
     2881 attgcttcaa agttaccgaa acgctgagca attttatagc cgatatttcc tgactgcaat
     2941 tctggaaata caaagactgt tgcttgacca gctacttctg aatctggcgc tttcagttgt
     3001 gcaactgaag gaacataaga agcatcaaat tgcaattcgc cgtcgatcat gtattgtggc
     3061 gctagttttt tagcgatttt agttgcttca actactttgt ctacttctgg cgatttcgct
     3121 gagccttttg tcgagaagct catcattgct acttttggtt cgatatcgaa caattctgct
     3181 gtttttgcag aatctacggc gatttcagcc aattcttgcg cagttggatt cacgttgatc
     3241 gcacaatccg aaaagacata tttttcttga tctcttccac gtaccatgat catcgctccg
     3301 cttgtccgac tgatgccagg ctttgttttg atgatctgaa gtgctgggcg aacagtgtcg
     3361 ccagtcgaat ggatcgctcc agagaccatt ccgtctgcaa tccccatata cgtaagcatc
     3421 gtaccaaagt aattcacatc ttttaaaatc ttttctgctt gttctttgga tgcctttcca
     3481 tttctacgtt caacaaaagt atccaccatt tcatcccact tatcgtaatt atcagggctg
     3541 atgatcgtaa agctagatgt tttgattcct ctggcatgcg ctgcatttct tatttcttct
     3601 tcgttcccta ctaaaatggg ttccacaagt tcttctgctt tcaaccgggc agctgcgcct
     3661 aaaatacgag catcagtagc ttccgggaaa acgattttga tcccacggcg aacaatttta
     3721 aatcttaaac tatcaaacaa ttccacaaga tgacctccag acgtttttat atgtattatc
     3781 atacactatt ccagaaaaaa agaacagttt attttatctg tatcagtcaa aaatgctgga
     3841 aaaattaagt ttttcacata caaagcgaac tgcactataa caggaaagcg ctgttttatt
     3901 acactgtttc aggcagttgc caatcaatcg gttcttctcc taacgcaagg agcgcatcat
     3961 tcgttttcga gaagggtttg gaaccaaaaa agccacgact tgcagataac ggactgggat
     4021 gtggagatgt tatgatgata tggcgactct tatcgatcat tttgattttt tcttgtgccg
     4081 gttttcccca caagataaac acgattggtt tttcccgttc atttaatttt tcaatgatcg
     4141 tgtctgttaa tctttcccaa cctttcccgc gatgagaata cgcttgccct tcccgaacgg
     4201 taagaacggt gttgagtaaa aggactccct gtttagccca tgacactaga tttccatgtt
     4261 gaacaggtgc gattccaaga tcatcataaa gctctttata gatatttctt aacgatggcg
     4321 ggatctttac gccaggttgc acagaaaaag ataagccatg agcttgattt tctccatgat
     4381 aaggatcttg tcctaaaatc accactttaa cttcttcata aggagtcaat tccaatgctt
     4441 catagatatg atacatatct ggatggatct tttgggacgc atattctttt tttaaaaatt
     4501 ctcttagatg cagataataa tcttttgaaa attctgagga caaaacttct tgccaactgt
     4561 tatgaatgat ttctttcaaa aactccacct cctaataaaa agaataactc acattttctt
     4621 caatcacaag ggacaatctt caccctcagc acttgattaa tatggtaaac taggaacaag
     4681 aagcagaaag gaacgataat cattatgatc aaattaattg catcagatat ggacggcaca
     4741 ttattagatg cccatatgag tgtttctcct gaaaatgccg aggcgatacg ttttgcaaat
     4801 gatgccggtg ttgagttcat ggtcgctact ggtcgaaact atcaagaagc tcgcgcagct
     4861 ttagatgagg taggaatcga ttgtgcgatg atcactttga acggggcaca ggtatttgat
     4921 aaagaaggaa attcattgtt taccgtgtcg attccaaata atcaagcaat ctctgtttta
     4981 gatattctag atgctaacgg tatttactat gaagtagcaa ccaacgatgg tctttattct
     5041 gaaaatcaag cgaaacgaat tgaaagtttt gcttccatgg tggctaccca tttacctcac
     5101 cttacgtata aaatggcgat tgccatggcc tcagctaagc tggagttatt gcacatcaca
     5161 tacgtggaca gtattcgtgc tattttggaa gaaaagaatc tggaagtttt aaaaattatt
     5221 tgttttcata cagaagggcc agctgtatta ggtccagttg gaaagcagat ttctctttta
     5281 ggcgatctag ccgttacttc ctctggtcaa aacaatatcg aagtgaacca taaaaacgct
     5341 caaaaaggaa ttgctgttgc ccatgtcgct cacgagcgtg ggatttcttt agaagaagtc
     5401 atgacgattg gcgataactt caatgatgtc agcatgctgc aagtagcagg agtcagtttc
     5461 gcaatgggaa atgcagaaat cgaagtaaaa gattatgcca aatatacaac ggacacaaac
     5521 cttgaatctg gcgtaggaaa agccatattg cgcgcgattg cagaagactt gtagttttat
     5581 ctagaaaaga gggatataga tgtcagaatt tttcattcag gaaaagcagc ttggacgtgc
     5641 aactcggaca attgtcaaaa acgaaaaagg acattccctg tttttgatgg ttggtcgctg
     5701 gggaacaaag ggcgatgcat tgtctcttta tgccatgaat ggcgatctcg ttgctcacat
     5761 caagcagata agcctgacat tcggtacgcg ttttgagctg tataaagagt tcgaaaaggt
     5821 gggaaccatg cagaaaatat tcaattggcc cggtgacttt tattatattc gtagacttca
     5881 ctggacagtc caaggtgata tctataatca tcaatatcaa atccatcatt tcaatcagca
     5941 aatcatgaaa atggataaag caacactttt ttcaggagat tactatgtat tggatgtctc
     6001 aaatgatgaa gatgctccag tttgtatttg tattgctgcg gttttagatt actggctcta
     6061 ccgtaaagac aaaagtcgcg ataagcctgt ttcttaccga cttaacttaa gttaaaaaga
     6121 tgtacctgaa atgcggaaat acgcatttca ggtacatctt tttagatatt cttttgcata
     6181 tgatcataaa gatgaccact gatcatccgc tgaccgacaa ctttgaagtc atggcgttcg
     6241 tataattttt tagcctttgg atttttttca tccacactta gaccgatgac ggagcgatta
     6301 gctttcttcg ccaatttagg taatgcttct aataatcgcg aaccgatgcc ttgtcctcta
     6361 aaatcttctg atacactgat agagtccaaa taccattcgt tgggaaacgt ttctttatca
     6421 atgaacaaac gtgtagacgc atctagctga tatttctcta agataggtac cagtggctga
     6481 tcgatgattg attcttcttc atctgtataa ccgtaagcaa ctcctgcaac tttaccgtct
     6541 atttcttcta cgatacctcg tgaataactg taacgataat ttggatcagt gattgcttct
     6601 tctaaaatct ctaaagtctt ttgttcccct gtctgcttca aaaatggcag ttccatatct
     6661 tttagaatca ctaagatcaa tggggcgatt tctggagcat cttcttttct cgcaaaacga
     6721 atcatagttt cctctccttt tctccattct aacatgcaga aaaagaaatc gcaaaatcgt
     6781 tattttaaaa aatcttcaat cttttcagta atgaaataac catgag
//
LOCUS       DAFTHM010000119         6791 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFTHM010000119 DAFTHM010000000
VERSION     DAFTHM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.119"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            107..1561
                     /locus_tag="L7C88_002472"
     CDS             107..1561
                     /locus_tag="L7C88_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBP9559266.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEELENKLAPADTMEDELHDAVVPSH"
     gene            1577..2608
                     /locus_tag="L7C88_002473"
     CDS             1577..2608
                     /locus_tag="L7C88_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBP9559267.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVGIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            2615..3802
                     /locus_tag="L7C88_002474"
     CDS             2615..3802
                     /locus_tag="L7C88_002474"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBP9559268.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            3958..5340
                     /locus_tag="L7C88_002475"
     CDS             3958..5340
                     /locus_tag="L7C88_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBP9559269.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            5312..5698
                     /locus_tag="L7C88_002476"
     CDS             5312..5698
                     /locus_tag="L7C88_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559270.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(5898..6566)
                     /locus_tag="L7C88_002477"
     CDS             complement(5898..6566)
                     /locus_tag="L7C88_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBP9559271.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFSLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT         2112 a         1294 c         1380 g         2005 t
ORIGIN      
        1 aaaaggaagc gatttcttgt taagtttaag tcattaaaag atctttgtta ttcgttgtaa
       61 ccggtttact tagtattata tattgaacag gagaggaata cagattatga aaagcaaaat
      121 gatccaacgt gtgtcctacg ctttaggcgc ttttggacac gacacattct atgttacatt
      181 aagcacttat tttatggtat tcgtgacaag ccagatgttc gcaggaacag ataaggcaac
      241 gaatgcaaaa atgattgcta cagttacaag cttagttgta ggtatccgct tagttgaaat
      301 tatttttgat cctttgattg gtggcatcat cgataatact cgtacaaaat acggtaaatt
      361 caaaccatgg ttagttatcg gcggcgttgt tagttccgta ctcttggtag caatctttac
      421 caatttcttt ggcttagcta ctcataatac gactttattt atcatattat ttgcaatcgt
      481 tttcatctta ttggatagtt tttattcatt taaggatatc gctttttggt caatgattcc
      541 agctttgagt acggaaacaa aggaacgtga aaaatttgct acgtttgctc gtttcggctc
      601 ttctctaggt gcaaatggta ctactctagt cgttgtccct atcgttactt tctttaccta
      661 tcttgttact cataaacata ttgaaggcgc ttcaggctgg ttctggttcg gtgtgattgc
      721 tgctgttatt tcaggcggta ctgcgattat cactgccttg ggcacaaaag aagtcgatac
      781 tgcgatccgt cagcaaaatg aaaaagctgg gatcaaagat gtgttcaaag cagttgctca
      841 aaatgatcag ttgatgtggc ttgcccttgc ttatatcgct tatgcgattg ccaatgtagc
      901 aacaactgcc gtattattct acttcttcaa atatgtactt ggccaaccaa ctgaattttg
      961 gatcgttggt ctagttgctg ccttacttgg tttagtagct gttccactat tcccaatgct
     1021 tacacgcgtc atctctcgtc gctacgttta ccttggaggg atcgcaatga tgatttcttc
     1081 ttactttttc tttacgatcg caggttcaag tttgccaatc gttatcatcg ggctagtatt
     1141 gttctacttc cctcaacaat tgattttctt atccgctttg atgacgatca cagactctgt
     1201 tgaatatggt caatggaaaa atggtatccg taacgaagct gttactctat caattcgccc
     1261 tttactagat aaaatcgctg gtgctttgtc taacgggatc gtagggtttg tcgctatcgc
     1321 ttctgggatg actggtaatg ctactgctgc tgatatcact gctcatggcg taacgacttt
     1381 caaagcttat gcattctatg ctcctgctgc tttgatgatt ttctccgcta ttatttttgc
     1441 ttggaagatt acattgacag agaaaaaaca tgcacaaatc gttgaggaat tggaaaacaa
     1501 attggctcca gctgatacaa tggaagatga acttcacgat gcagtagttc cttcccatta
     1561 agaaaggatc ttgaaaatga agattacaga aaaagatttt ggccaaggtt atcacttgat
     1621 aaccttggag aacaaaaaca agctagcact ttctatctct gatttaggtg ctagaatcgt
     1681 cagtttaaaa tcaaatgatc gagaattagt tttgggattt gacaccgctg aagaatatat
     1741 cgaaaaagat ccgtatatcg gtgcttctat cggtcgcacc gcagggagaa tcgaaaatgg
     1801 ccgcttttct ctcaatggaa aaacttacca attagccaca gatccaaaaa ctggacataa
     1861 tctgcatggt ggtgctcctg gatttgaatt aaaaaaatgg tcttatgtca ttttgaatgg
     1921 cgaaaatgaa gcttctgtca tttttactac tacaagtccc gacggagaac atggttttcc
     1981 aggtacaatg gatgtggaaa tccgctatac tttgacaaaa gataatatct ggcgagtgac
     2041 ctctcgcggc accagtgacc aagatacttt attcaatccg acaaatcatg tttacttcaa
     2101 cttgacggga gatgcttctc agtcaatcga tcaacatgag ctttggctca atagcgaagc
     2161 ttatgctcct ttgcgaacag atagtattcc tataggggta aaagaaaatg ctgcaggaag
     2221 tgctttcgat tttcaaatac ctaaaaaatt agcgtccgtt tttgctagtg atttggatca
     2281 aaaaaatctt gttgacggaa tcgatcatcc atttttctta aaagaaaccg gcttgggtaa
     2341 agaagccgct cgcttgacta gccccgataa aagaatccaa gtaggtattg ctacagatgc
     2401 ttctagtgtg gttattttca ctgcaaattt cggcacagaa acaccagaaa tgcgcaaccg
     2461 aaaactggca catcacggtg gcatcacatt tgagactcaa acagctccag gtgcagagcg
     2521 cttctcagca tttggttcga ttcatttaaa agctggatca gtatttgaaa cagtgacaga
     2581 attcaaaatc aaaacaagaa aggaataact catcatggaa atcaaaagaa gcttaaacac
     2641 aaaatttgcc gaaacattcg gacctaaaaa aactacacaa tacttctcac caggacgcat
     2701 caatttgatt ggtgaacaca cagattacaa tggaggccat gtcttccccg cttccatcac
     2761 ttatggaacg caaggtgtag cagcacctcg agacgataat aaaatattag tttattccac
     2821 aaactttgac gatatcggtg tcattagttt tactttagat gagctagaat atgataaaaa
     2881 agcaaactgg gcaaattacg taaaaggaat ggtccttaaa ttaaaagaag ctggacactc
     2941 aatcgatcat gggtttgagt tgttagtgga aggaacaatc cctaatggtg caggactttc
     3001 cagtagcgct tcattagaat tattagtagg tgttgtatta gaagatctgt ttgatttaaa
     3061 aacagatcgc ttggaactag tccaaacagg taaaaaagta gaaaatgaat tcatcggtgt
     3121 caattcaggt atcatggatc agtttgccat cggcttcggt gagctagatc atgcaatctt
     3181 attagataca aatacgctga aatacgaaat ggttccagtg aaactagatg gttatgcaat
     3241 cgtcatcatg aatacgaata agcggcggga attggcagat tcaaaataca atgaacgccg
     3301 tagcgaatgc gaagaagcct tggcacgttt gcaaaaaact ttgcctatct cttctttagg
     3361 agacttagat gaagaagaat ttgaatcaac tattgaccaa atcggcgatg atacattgat
     3421 acgcagagct cgccatgccg tttctgaaaa tcagcggact ttgaaggcaa aagctgaatt
     3481 agaagctggg aacttagaag catttggtca actgttaaat gattctcacc actctcttcg
     3541 ctatgattat gaagtaactg ggatcgaatt agatacacta gtagatgctg ctcaaaaaca
     3601 agaaggtgtc ttaggtgcac gaatgacagg agctggattt ggtggctgtg cgattgctct
     3661 tgtcaaagaa gaaaatatac ctgccttcaa aaacaatgtc tatgatgaat acatgaaagt
     3721 tgtcggctat gctccggaat tttatgttgc acacattgga aatgggacaa caaagatcga
     3781 tccagaagct gttcatgttt gataaaaaaa tcaacgatct cagctaaaaa caaatagata
     3841 aaaataacct ctcagcaatt tccaaatgtg agccttttgc tcgtatttga aaattgctgt
     3901 tttttattga cacggaaaga gaacgtgtgt tctaattgtg ttgaagaggt gattgttatg
     3961 tgggcgaatc aaaatccggt atttgtttat gaaaaagaac cttcaagaga tattttatgt
     4021 attgactgca aatcttttta cgcctccgta gagtgcgttg aaaaggatct tgatcccctt
     4081 acaactaaat tagtagtcat gtcctatccg tccgattcga cagaaacacg gggtagcgga
     4141 ttaatcttgg cttccagtcc tgcagcaaaa aaagcttacg gcatcaccaa tatcagccgt
     4201 gccagagatc ttcccttccc ctatccaagt gatttatata ttgttgcccc aaggatggcc
     4261 tattatatgg aaaagaacag agaaatcaat tctatctata aaaaatatgc agacgaagcg
     4321 aaccatcatg tctattccgt cgatgaaagc ttccttgatg taacaaatag catggcactc
     4381 tttggtaaaa caaatgcgta cgacatggct aaactgatcc ataaagatgt gtttgagcag
     4441 accggaatct acacgactat aggaattggc gataacccgc tacttgctaa actagcctta
     4501 gacaatggct caaaagacgg aaagcaaatg tttgctgaat ggcgttatga agatgtacca
     4561 gaaaagttat ggaaaatctc agatatcact gacttttggg gaatcggcaa acgaacagca
     4621 aaacgtctga aacaaatggg tatacattct gtttatgatt tagctcacgc ggattattat
     4681 cacttgaaaa gcaagctagg ggtcatcggt actcagcttt atgcccatgc ttggggcatc
     4741 gatcgaagtt ttttgggaca agaatataca ccaaaatcaa aaagtatcgg aaatagtcaa
     4801 atcctagata gagattatac aagacgagaa gaaatcgaga tcgttatcaa agaaatggcc
     4861 gaccaagtcg gcactcgctt gagacgatct gcagcaaaaa cacaagtagt cagcttatgg
     4921 gtaggatact ctttaggcta tcttgatcca aatggcaaga ccgggtttca ccagcaaatg
     4981 aaaatcgaag cgacaaatgc tagcagagat ctagcagatg ctttattgac cattttccac
     5041 cagcattacc actaccagga tattcggcgt gtaggcgtga actgttccga cctcgtatac
     5101 gcgacaggtt tacagcttaa cctttttgaa gatcctgaaa agcagataaa tgaagcgaaa
     5161 gttgattttg ttgtcgatac gattagaaaa aaatacggct ttcaatcaat catccatgcg
     5221 catagtctct tgcaaggagg acgcgccatc gcacgtagtt ctctcgttgg cgggcatgca
     5281 ggtggtatga gtggattaga aggtggaaaa gatgagacgg acagcaaaaa aattcattga
     5341 ctataacgag tatcgagatc ggccatttgg attaaaatgg gggactgctt ttgcgatgga
     5401 agaactagtc aacggtatca aaaaaaatga agaagaagca cgcaaacagc ctcttcctaa
     5461 acaacaaatg acattgcaag aaatcgatag tatactgaca gaagcctttt tatctcgtaa
     5521 agcagtaatc attcagctca atttaaaaga tgaatttgga agactcttgg atgaggtcga
     5581 agggcacttc attggtgaag cctatgaaga ttactttatg attgaccatc agccgatatt
     5641 gtgggaagac gtacggtata ttgagttaaa ggaaacaaaa aaatggtttg tgacatgaga
     5701 ggttgtgaca gaagtgatca acttcaaaaa ataagaaagg atttttcgaa aattgcttct
     5761 taaatttttg tggaattttg gcttattttt cgaagaagca acttctggaa caacgtatat
     5821 tagatatcag aggttgtgaa aaagtcgctt agttttgagt aacaagccaa ggcgctgatt
     5881 tcacaacctc tgtctatcta tccatctatt cggtaagatt catgcatgac gtcttcttta
     5941 tttagtatgt agagcccttt ttcttctgac cattcaacat aaatcagctg ttttacatct
     6001 gcatagcctt ctttcttcaa gttctccata agccatgctt cagtcaattg attggactga
     6061 agcactttat gctgaatttg cccttcatct acaagcagga tcgataaagc tttgtcttca
     6121 tctgattttt tcaatacact catttgacca gcattctcta ggataacatg tttggcattt
     6181 tcaagagaaa agcattcttg ctgtcttaag attgctcgca actgctccat ctcgatatgg
     6241 ttatttgtca actctgtcat gttgatgacg ccgtctttga ttagaacaga tggctcgcct
     6301 ttgacccaac gattgacctt ttcatttttt tggacgatac gttcgatacc ataaatcatt
     6361 actgcccaaa gcgcaatggc aaataggaca tgccctacat ggacattgtc atcataggtt
     6421 gattcttcta agatcccacc taaaacaagc gtatagacta aatcaaacgg tgtgatttct
     6481 gacatggatt tcttcccaag caaacgtacc actaataata aaccgatcaa cccgaacacc
     6541 agtttcattg taattgaaaa aatcattttt tctcccccta actatctgtt aattaaatta
     6601 tatatgcttt ctcacgaaca cgcatggaat atacaaggaa gaaatgtatc cttttactaa
     6661 aaaaaggact gtgacactgt agtgaccccc aaaagttaga cttttttgga gtggagaaat
     6721 ccactccttt tttttatgct ctaaaatgat atttttacac aaccgttacg gttgttttac
     6781 gaaattggac g
//
LOCUS       DAFTHM010000120         6691 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFTHM010000120 DAFTHM010000000
VERSION     DAFTHM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.120"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            299..895
                     /locus_tag="L7C88_002478"
     CDS             299..895
                     /locus_tag="L7C88_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBP9559272.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(953..1435)
                     /locus_tag="L7C88_002479"
     CDS             complement(953..1435)
                     /locus_tag="L7C88_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559273.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1541..1738)
                     /locus_tag="L7C88_002480"
     CDS             complement(1541..1738)
                     /locus_tag="L7C88_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559274.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            2033..2791
                     /locus_tag="L7C88_002481"
     CDS             2033..2791
                     /locus_tag="L7C88_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBP9559275.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            2851..3279
                     /locus_tag="L7C88_002482"
     CDS             2851..3279
                     /locus_tag="L7C88_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559276.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            3325..3397
                     /locus_tag="L7C88_002483"
     tRNA            3325..3397
                     /locus_tag="L7C88_002483"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3358..3360,aa:Gln,seq:ctg)
     gene            complement(3547..3918)
                     /locus_tag="L7C88_002484"
     CDS             complement(3547..3918)
                     /locus_tag="L7C88_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBP9559277.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            4133..4318
                     /locus_tag="L7C88_002485"
     CDS             4133..4318
                     /locus_tag="L7C88_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559278.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(4401..4589)
                     /locus_tag="L7C88_002486"
     CDS             complement(4401..4589)
                     /locus_tag="L7C88_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559279.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(4613..4876)
                     /locus_tag="L7C88_002487"
     CDS             complement(4613..4876)
                     /locus_tag="L7C88_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559280.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            5034..5291
                     /locus_tag="L7C88_002488"
     CDS             5034..5291
                     /locus_tag="L7C88_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBP9559281.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(5362..5553)
                     /locus_tag="L7C88_002489"
     CDS             complement(5362..5553)
                     /locus_tag="L7C88_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559282.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(5694..6014)
                     /locus_tag="L7C88_002490"
     CDS             complement(5694..6014)
                     /locus_tag="L7C88_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559283.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(6037..6471)
                     /locus_tag="L7C88_002491"
     CDS             complement(6037..6471)
                     /locus_tag="L7C88_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBP9559284.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
BASE COUNT         2098 a         1303 c         1022 g         2268 t
ORIGIN      
        1 actaattttc tataaaagca agtaattttt aatggcaata tcataaaaaa aagaagatag
       61 agatttaata attatatatc agctgttttt ttcaaataag caaaaattcc taaaacacaa
      121 caatgaaagc gataactaag aaaatcctta cataacgatt tttcttatta aaattgtttt
      181 ttgaacttcg cttatttttt gtgagcatat ctgtttactt actttttgta aggtgctata
      241 cttcatttcg taatcaatta aaaaaatgca aaacgcaaat caaaggagaa attttattat
      301 gacaactttt actgacactt tgaaaaaccg ccgttcaatc tatcatctag gacgtaatgt
      361 ttcactttct aatgaagaat taacaacttt gatcaaagaa gcaattaaag aaagcccaac
      421 tgctttcaat gctcaatcaa cacgcgcagt tatccttttc ggagatgcac atgaaaaact
      481 ttgggaaatc actgaagaag cacttcgccc attgactcca gcagaagctt tcccaaatac
      541 acaaaacaaa ttagctggtt tcaaaaatgg ttatggtaca gtattattct tcaaagatac
      601 tgacgtggta aaaggtctac aagaacaatt tgaattatat gcagacaact tcccagattg
      661 gtcagaacaa tcaaacggaa tcgcaacagc taatacttgg gtagcattag ttgataaagg
      721 attgggcgca aacttgcaac attacaaccc agttattgac gaagcagttg caaaagaatg
      781 gaatatccct tcaaactgga aactacgttc gcaattagta ttcggttcac cagaaacacc
      841 ggctggggaa aaagaataca tgaacgatgc cgatcgcttc cgcgtatttg gataatttta
      901 tttgaaataa aaaacagagg ttgtgacaaa catcttgtcg caacctctgt ttttattctg
      961 gatcaatcat aatatcaatc tctgcctcat cgtttaagcg ttgggacaaa aatggaacta
     1021 attcttctaa tgatgcagaa aatttcagca tcggtcctcg ccatccgttt cggaaaaaat
     1081 tcatttttac gattttagaa ccttttggct gatataatac aattttattg atctcagaaa
     1141 aaggaacacc ttttttgtca aagctattca aaacaagtcc ttcttctgtg attcctctac
     1201 tgtccaacaa aaaactaata aaaatcattg ctgacaagat cccttttgcc aattcatctg
     1261 ctgtaggatg actgatgagt gtataccaaa tgactagtga cactaagaag ggtatcacca
     1321 agtagaccca tcgatttcgc acagtccgat aaataatttc ttttcgaacc agccaaagaa
     1381 ataaaaacat cacaacaacg aataaaaaca atagaaccgt aaagaatgtt accatgacaa
     1441 ctcgcctcgc tttttcttct ccagaaaata ggaaaagaat actgatttac cttctcaaag
     1501 aaattggact tgcagcacgc cgcacgtcca attgttttct ttattcaaat gtatcatatt
     1561 ttgcaacaac catgcttgct ttttcatcta ataattcttg gtcctctgca gcacattggg
     1621 caactttgac cacggcgcag tttgtcattt ttgatacaac ttcaccaatg accgtttttg
     1681 taaaaccaat tggtttgcat gcatattgtt ctcctaaatt aatcatttct tccgtcatca
     1741 aaatcctcct aaactgctgg aacttttctc cacattacca ctgctatttc tttggagatt
     1801 taactcattg atttttattt acagttaaaa atcaacctta caggcattat agcgtactgt
     1861 tttcgttttc acaattaaaa cagctgttgt atttagaaga atttttttca aaaaattaaa
     1921 acatattcct taaaaactaa ttatttccta catattaaaa tataatactt ccatttccaa
     1981 taaaaataca tttataatag gaaagataaa cagctgaaaa gggagatttc aaatgaagaa
     2041 aaaaacgttc aaaaaactat tgtttctagg gggcacagct gctcttttat taagcggtac
     2101 aagttattac ctacatatcc attctccaga acatacaatg aacactgcac aaaaaagttc
     2161 aacacaaaaa acgaaaaaga caaaagagaa agcagaagtt ttactagatg ttccattaga
     2221 gagccagttt gattctcctt ctttagaaaa tggctgtgaa gtcacttcgc tttctatgct
     2281 tttatctttt tatggttatg aaacaactaa aaaccagtta gctgagcaat tggattacgt
     2341 ccctgttttc aatgcagatg ggactcatgg cgatcctaat gaaggatttg ttggtgatat
     2401 cagtggcgga gactgggcta tggtcgtcta tgttccccca gttgcctccc ttgctcagca
     2461 aatcgtccaa acggattatc acacttttcc aaaaaccgat gctcaactcg atgatatcaa
     2521 aaaagcacta tctaaaggaa atcctgtctg gacttctgtg actatcaatt ttgaagtccc
     2581 agatgaaact gattttatga cttggaccac aaataatgga gaagtaagag tcactcctct
     2641 tgttcatgct tgtgtagtca ctggatatga caaagaaaat atttatgtca acgatcccta
     2701 tggtgtaaaa aatcgagcag taccgatcaa cgatttttcg gcgattttca ctgcaatggg
     2761 tggacagatg ctaactttgg agaaaagcta gtaattcaaa caaaaatccc ttatactcaa
     2821 gataccaaac ctttgaaggg agcgtagata atggaaaaat tcacacataa aaaaatggat
     2881 ccaaatgaaa ttccgattat ttttgtccgt gactgcaagg gaaatgttca aggtaaagtc
     2941 tctattaatg agtggaacga gcgtcgcaga cctgctaccc tcaatgaact ggaaatcaaa
     3001 ttgtatcgtc aatctcttgt ttattacgca gatcaagagt acgagaaagc caccgattta
     3061 ttgaaatttc taattgctcg aacagagtat actcgctttg aatatattga acgtttagca
     3121 aacatctatc atattatgaa tgaacctgtc aaagaatatc agttattgga caccgtcttg
     3181 tcagtagcag aactgattgc ccttcctgct ggattagaaa agaaactagt acgccgcctt
     3241 ttacgagtaa agcaacaact atccgatcaa gaaaaataac ttgcgttttt ttaggaaagt
     3301 gctatgatta ttttgttgaa taaatgggat gtagccaaac tggtaaggca cttgactctg
     3361 aatcaagcaa ttgtaggttc gaaccctgcc atcccaattt gatgtgcttg ctgaaaaaat
     3421 gaaccccctg taaaagaaca atctttttgc agggggatta ttgtattatt tttactactt
     3481 gtatttagtt tacataatta aattatgaat aataaaatcg ggcgtattct taatacaaaa
     3541 actgatttac ccaataattg ctaatgcttt ctccggaact ttttctctag gaacttcctc
     3601 atacgtttct atgtgtgctc ctttattgct aattttcaaa taatgatttt cttttaacac
     3661 agaaagacca ttaaattcaa ccgttcgttc tttcccattg gcatcagcag ctttctgcac
     3721 ataccttgct gtaccatatt catttacttc ctctggtttt tgtgtcttta catagacctc
     3781 tcctttttca actaatggat ttagctgatc aagtatacca gggatttctc cataacttcc
     3841 ttcagtataa tatttcagtc caaatagcaa aataccacta atcgccgcca gtccaatcaa
     3901 atatttaatc actttcatct ttctacctcc ttgttatata ttcagtatat gggtcagtta
     3961 aagaaattcc atccgtccca agttggagat ttttctccta ctttagaagc gagaatcgag
     4021 tgttttttta gtaaaaatga tcgttatttg atattattga cgtgtggata aatcagtttt
     4081 tctcgttttg tccatgtaaa aaatcatgtt gatagcaaag gatgtgttca aaatgaatca
     4141 agaagaatta tttcaaaaag tcaaggaaat gattaagaac ggcaatttcg atggcgcaaa
     4201 acgatttatc gaagaacata aagaacaatt aggaccttat aaagagaaag cccaaaatct
     4261 tttaaaagat gtaaatatcg acagtgtcaa aaacaaattt aaaaatctat tcaaataagt
     4321 aaaactttca cttttgtaaa atcaaaggag gacaatgctg ctgcatcgtc ctcctttggt
     4381 tcttttctga atacttcata ctaaaataaa cgtgtcggat cgtaatgata agtcacattg
     4441 ccgttcagtg aggcttttcc caccacatat ttacgattct ccaacttcag ccacgcttct
     4501 cgaaaagcca ttaattcttc tctttttaca tcaatctttt cgatttttcc atcgatcaaa
     4561 tcttgaataa gttgttcata tggattcatt tttttcctcc atctgctgtc aatcaataag
     4621 ttgtaaaaat aggttcatat gcttttttgg tatctagatc ttctctgact ttgactgtcg
     4681 tataaataat tttttctact gggatactat aataacttcc ttcaccatta ttgaatcggt
     4741 gaacgtcttt ctttgctaaa ataccattta ttttattcgt cagtacacgt tgttcgacac
     4801 tgttacttac aacatagtaa atcacccgaa tattattgat caaatgcaaa tcgatttcta
     4861 acactacatg atccatgaaa atcccactcc ttctttcact ttgattatag caagtttctc
     4921 ctctaatttc aaaatcgata cagattttac cggataaatc cacaaaactg cttgcgccat
     4981 ttcgcacaaa gtgttatttt gtatcatgga ctttatttat cggaggcaat agtatgatcg
     5041 cgatcggtca atttgttttt tatattcctt tttttattat gataagcatt cttttctatt
     5101 acataaaatg gacaaaaaag aagttttcag ttttactggc ctctttacct gctgtatatt
     5161 ttacttatca aattttttct tttaggcatt gggaaacaac gtctgtatta ataacacaca
     5221 tcatcgaatt gacgctttca gtaatttttc ttattatttg gatctatttt ttatataaga
     5281 atcagaattg aatccctcgc atgtttaaaa agaaaacgat taaagatgca gcaaatttct
     5341 gccgatcttt aatcgttttt tctattctgt tataccaaaa aaatgtttga atcggtgaag
     5401 gatcgttcct tgttttaatt ctataaattc ttgtgcgatc gggtactttt cttccaaatt
     5461 ttctttgttc ttttcgatca ggcttttcgc ttcttcatat tttttatctg cacatagtgc
     5521 ttttacttcc tgtaatactt ttcctgcttc catttgcctc accctcttgc cattttattg
     5581 ctttaagttt tatttaagtt atacgcatta ttctagtttc atcccaaata accttttttc
     5641 atttttactc ctcgaactaa tcagttttct aaaggctgat tggttcgtct tttttatttt
     5701 tcctccattt cattctgctc ttctgttaat ttatctaatg ctttgattga tgctgcggct
     5761 cttgcataat catagctgta taattccata aatttatcag gcagaacaaa ccacgctgga
     5821 tgataaccgt tagctgtgac agggaatcct ttatcttgtt ggttatctcc atcccatctc
     5881 agagcaacac ctttttttcc tttccacttt actaaagcga tcgagtatcc cttctttgtt
     5941 tgtgtgccgt cttcaataat tgctaaaatt tctatttttt cttttggcgc acggacttct
     6001 tgaggacgaa ccattttcta ttcctccctt atctcattac ttcacgacca acacactgca
     6061 aggggcatgt gatacgacat aagaagcggt cgatccaact aatgcttgtt gtatagcacc
     6121 ttttcctgtc gctcccataa cgatcaaatc aatattttct tgtccaggga tgacattggc
     6181 aatcaaattt cttggatctc cagtttcaac tattgcgtgg atctcagcaa tgccgtactc
     6241 tttggcatca ttgatttttt tcagcatggc tacttctgtt ctttgttttt catctgcata
     6301 gatttttgaa aaggcatagg cactatgggt cagctcaact ttgttgatga ttgacacgat
     6361 aaataagtgg gcttcattgt cctttgctaa gtcaagggct tcagcgaacg ctttgatcga
     6421 ttgtcttgat ccgtcaactg ctaccatgat gttctggtat cttttactca ttggaaccgc
     6481 ctcctttttc ttttattgta acatctcaag caaaaataca aaaaatatac gcaatatgta
     6541 aataaaatga tgaacaaaag caatttcttt caagttattt atacatttct tttctcatca
     6601 gaacacctgt tctaatccca ttatttctgc attatgtgaa attcctcatc atttttcaca
     6661 tcgagcgaac atcattctgt tacaaaaaac g
//
LOCUS       DAFTHM010000121         6644 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFTHM010000121 DAFTHM010000000
VERSION     DAFTHM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.121"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(1..859)
                     /locus_tag="L7C88_002492"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="L7C88_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="L7C88_002493"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="L7C88_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBP9559285.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="L7C88_002494"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="L7C88_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2603..3421)
                     /locus_tag="L7C88_002495"
     CDS             complement(2603..3421)
                     /locus_tag="L7C88_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBP9559286.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="L7C88_002496"
     CDS             3582..4271
                     /locus_tag="L7C88_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBP9559287.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="L7C88_002497"
     CDS             4285..5787
                     /locus_tag="L7C88_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBP9559288.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="L7C88_002498"
     CDS             5800..6276
                     /locus_tag="L7C88_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBP9559289.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="L7C88_002499"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="L7C88_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DAFTHM010000122         6603 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFTHM010000122 DAFTHM010000000
VERSION     DAFTHM010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.122"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..793)
                     /locus_tag="L7C88_002500"
     CDS             complement(<1..793)
                     /locus_tag="L7C88_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBP9559290.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQ"
     gene            854..1594
                     /locus_tag="L7C88_002501"
     CDS             854..1594
                     /locus_tag="L7C88_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9559291.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(1680..2438)
                     /locus_tag="L7C88_002502"
     CDS             complement(1680..2438)
                     /locus_tag="L7C88_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBP9559292.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(2435..3463)
                     /locus_tag="L7C88_002503"
                     /pseudo
     CDS             complement(2435..3463)
                     /locus_tag="L7C88_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(3483..6593)
                     /locus_tag="L7C88_002504"
     CDS             complement(3483..6593)
                     /locus_tag="L7C88_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559293.1"
                     /translation="MVTSVFADVEKTNESTQSENQSFDKTTFSEESITSETTESQSEA
                     STNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYSEAATTEELAQLLADESVTK
                     IRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINEIPQSIEFQNFKGTAAHPGG
                     LTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYDGSKLGLIYAPRATVTLDGV
                     SGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGPYLGKFYGFLDSGDETGSGK
                     TAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMFEVSGSGSEFSVNTKINITN
                     DNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGDSSQIHVSSGGQISVKMAGD
                     DDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAVRFENGTQKLTVTNGGSLRV
                     RNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTVTGEKSNIDIRADSGATVDT
                     TGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDLESPTYFDFQNKRIGSETNG
                     IGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPDYFSDMTDLSINGTDLGNFV
                     SSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVPTNADKKIYGHVVVPEGVEA
                     KPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDENEGAGYNPWGEGEQGGLFEV
                     QVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVDVIPPEPANLSTTLINAASR
                     TITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPENQLFAGDVLEIVLNDQAGEA
                     TAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKIVVEGGLSFLAPSKLDFGQI
                     KATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQPFTNDAGFSMQDVLYFKKG
                     EEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLVLTKENQIAGNYSAEITWTL
                     ADAPTE"
BASE COUNT         1859 a         1389 c         1172 g         2183 t
ORIGIN      
        1 gttgtatttg cggtttttca aaaatagctg cagaatgatc ttctaatatt tctaaaaatt
       61 ccaacgtttc ttttttattt tcctgaagag taatttttaa tgaaaacagt agacttttat
      121 aatcatgttt gaattcctct agatgatggt aatattcttc atttatttga tacagttgaa
      181 gcgattcctg atgttgtctt tcttttactt ggaaactgat caacataatg gaaaaaaaca
      241 aagaaaaaaa actgatgact atcgacaaaa gagatagaag cagataatta gatgagcgga
      301 agtgaacact tcccaatacc aagtaaatca cgccccagct taataaaata caaatacctc
      361 caaaatagtg ttcagttgga taagtaaaaa gcaagttgag aaatctcgtc tgtttgtcta
      421 tactttttac taatagatag aaaataaatg cgataagtag tgcaaaaaaa cttgctgttc
      481 caagatgtct ctttcctaaa taatccatca gatcaaaaac cagaaaaaag ctgagtccag
      541 tgatagcaaa aaaaagatta ctgatcaaac agctgataaa caggtttttc gtagtaaaat
      601 aaaaaagaaa catcaataat aagccaacta ggtaaggaaa gctcacttta gggataggaa
      661 gtaaaagtgt caccaccatc aaagctatac aaccaaagct gttttttact agcagttgtt
      721 tcgaaaagaa taaatagata cctaaatcta aaatcaaagt aaaggtcaaa taaagtgtca
      781 ctgttgcgac catcttattc ctccattgtt ttgtttcaaa atgtacacat atttttttaa
      841 taggagcctg catatgaaaa agtattttat catagaagat aaccagtttc acagcgaatg
      901 gatcatcaga gaattggtca atcatcatat cgagaatatc gtgcagctca cttctatctc
      961 tcaaatcaat cagttgatcc agttgggcac tattgataat cacgatgttt tctttatcga
     1021 tatcgacttg aagcaatcac tcacaggtat tgatgtcgcc gaacaaatac gtaaaaaaaa
     1081 tgcacatagt aatattgttt ttttcaccgc ttatacgaat tttgcagtag agatcatcaa
     1141 tcggaaaatc cttccgattg gatatatcag aaaagacagg aatttatctg aacaaattcg
     1201 tcaagtgcta gaacagatca attggaaaga acagcagatc gtaaatgtcg ataaaatctt
     1261 tattgatcaa aaaggtggaa gtctcgtcct gtatcctcgg gaaattttat atattgaaag
     1321 tatcaaaggt ttgaaaaacc aagttatggt caaaacaact acagaagata aattagtgaa
     1381 tacttcttta aaacaattga agacagagtt agaaaagtat gcttactttt tacttttaaa
     1441 atcttactgt atcaacttat cgcaattgca gaaaattgat tctgctcatt atgtgttaga
     1501 atttttcaac ggtgactcct tactcgttgg tcgaaagatc tttgaaaaga caaaggaacg
     1561 tttccatgac ttccaaaaaa ctgcttcgag ttgatgaata agagctgaga cgtaagcata
     1621 gcagatttca gggagtgggc cttgaatcgg ctccactccc tgaaatcgtt gatatgattt
     1681 tacgcttcct cttctgtagg agcatctgtt aacgaccatg tgaatgttga aacgtagttg
     1741 tctacagcat aattggatac aggaacaaat aattccactg attgtctccc ttgttccaca
     1801 ttctctccta atgaataaat ccatgtgcca atcccttcat ttgctcctgc agttactaga
     1861 tctactgcct gatctgctgg gatttcgatt ccttcagcgc cagttccaga aacggtagat
     1921 ggcattccac tgctattagt tgcgctattt cgaatcacgg cgtttttgaa tttcaccttt
     1981 gaaccagtta gtttattcgt atcagatgtt gtaccaataa attctgttcg tttgactgat
     2041 aatttccaac cggcataatt tccgctttta tccgttactt gtacgaaatt ctgtacttgt
     2101 gtttgtgctc cagtactgtc cgttccgctt tgtaatgcag catatactgt ttttgctgta
     2161 cctaacttga ttgttccaaa atcaagatct ggagcttggt caatcgtcag taatccggat
     2221 gttccctgat ttggttcgtc aggtgtaaaa ggagtatcag gatcatttgg atcaacagga
     2281 ggaactggaa caacgtcttc aggatttgca gcatctggtt tggtcacaga aatcgttcct
     2341 tctgtagtgg ctgagctctt attctcagca aaaacacttt gtgtacataa taatagactt
     2401 ccagctagaa cggtacttaa tgcaattgtt tttttcattt ctttttcctt ctttctttta
     2461 aaataaataa tccagcaaat aagccaataa gaatgactcc aacaagtatc agccatcgcc
     2521 agtcaaatgt ttctggctga ttttttaaat caatatcctt ttcattcaat tggtccgctg
     2581 catcatcagt tatttcaaaa tcggtatgga gattccagcg tttttctttc caagcaccct
     2641 tcacaaccgc ttgataatgt cccggagcta atttttttcc ttctaatggg acaagtaaat
     2701 caaaatttgt attgggtgct acatctattt tttctttttt tattgaaagg taaggctctt
     2761 ttgtttcttt tttgtagatt tcaaccgatg tagtcaagcc gaacatataa gaagcatttg
     2821 gattttgaag attcgcctta atcacatttc ttccatcgct ttgatccgca taagcttttt
     2881 ttaatttcaa atctggggaa gactcttttt cgctatttca aatcaagatt gctttcactt
     2941 gagaaaactg attgacgaca ccaactgtac ttttgttaga aacgttctct tttttttctt
     3001 gaaacgtgat ccctcctgcg accacaccag ccagctcttt ttctggcgct ttcagtgaaa
     3061 gtgtctcagt gaccgcactt tgaggaggaa cagttatttc tcccactgtt tttgctaagt
     3121 ttttcatatc ataacttaat gtttcatcaa atttactttt tgattctcca tattcgatca
     3181 caccgtttga attcgtcgta gcggagtgga tcaatgtctc aactgttact gatttatctg
     3241 ttcggttaaa gaccgtgtag gggatttcct gtgttttccc aggctccatc cttacattta
     3301 tatatgtttt gttcttatca atctgattag ccggtaattc aaaatctacc gcaaaattga
     3361 attcggaggc atggacaggt gtctgccaaa ggatgaatcc aaggagaagg atcataagta
     3421 aagagcagtt gtttcgatga cttttattcc atattcgatt catcaatcat cctccttgat
     3481 ctttattctg tcggcgcatc tgctaatgtc catgttatct ctgctgagta attaccagct
     3541 atctgatttt ctttggttaa gacaagttta aacgcccgac cgttatttaa atattctgaa
     3601 taatctgctt gcacattcgt tgaattttgt cctctgacaa tttccagttc ttcttcattc
     3661 actaattgat actcctctcc tttcttgaaa tataggacat cctgcataga aaatcctgca
     3721 tcatttgtga aaggctgaga taattttatc gttaagatcc acggattttt cgtttctcgc
     3781 tgatcataaa tccataattt ttcctgtata tccatttggc caaatgcttc ttgtgtcaaa
     3841 ccagttgctt tgatctgacc aaaatcgagt ttggaagggg caagaaatga gagaccacct
     3901 tctactacga tcttcgtagc aggtgcaaaa ggcggggcat catgataaac aactggcgta
     3961 tcacttggat tgtgattccc aatttcatcg ttggtacttg gcttgttctg cacaccctta
     4021 gcagtagctt ctcctgcttg gtcgtttaat acaatttcta atacatctcc tgcaaaaagt
     4081 tgattttctg ggatagaaag aacaaattcc cctgtatcat caatagttgt ttctgacaaa
     4141 acagcttgat tttttttcaa tgaaaccaag gctcctgctt cacctgtacc tgtgatcgtg
     4201 cgagaagctg cattgatcaa tgtggtactt aaattagcag gttcaggagg aatcacatcg
     4261 actgtcgttt tggcagagtc cagttctgtc acttcttggc cacctcttac ttttttagca
     4321 gcaacaactt gcacttgatc ctccgttttt aatctctcat cattgggtac ttgaacttcg
     4381 aacaagccgc cttgttcgcc ttctccccat gggttatatc ctgccccttc attttcatct
     4441 gtttgtcctt gcgtgagagc agtaatttct acagatgatt tcgtcgtatc tgcgtaagta
     4501 atacgtaaag tcacttctac ttcgcctgtc caagcatctc ttggctttgc ctcgacacct
     4561 tcgggaacaa cgacatgccc atagattttt ttatctgcat tcgttggcac tcttaaggat
     4621 tcaatcatcg ggagctgatt attggcactg attcgattat aatttttcat tccggcacct
     4681 gtctgagcaa attcatttgt taaacctgca ctagggcttg atacgaaatt gcctaagtcg
     4741 gtcccattga tcgataagtc tgtcatatca gaaaaataat ccgggtcttt ttcaaagtta
     4801 tcgaatgttg cgcctgtttt tcgccataaa gcgatttctg aatgggcgat ctttaaagaa
     4861 gaatctccat ttccttggaa tacccagccg cctatgccat tggtctcgct tccaatccgt
     4921 ttgttttgga aatcaaaata ggtaggagat tctaagtcca cattcaacac atccccactg
     4981 atgatgccgg tcttatcttc ccctgttttc ccgaccatga ctaaataagt tttttcacct
     5041 gccgtaaaat ttaaatcaat atctccagtt gtatctacag ttgctccgga atctgcgcgt
     5101 atatcgatat ttgatttttc tccagtgact gtaaaatcag ctgaacctgg actttctaga
     5161 aaaccagaag cgtcataaaa ttggatcgct tgatttcctt gattgagtct gttcacgtaa
     5221 gatttgccat cacctgtatt tcttaccctc aatgagcctc cattggttac tgtcagcttt
     5281 tgcgtaccat tctcaaaacg aactgcgctg gaacgcccac tctgcttatc gatgtcgata
     5341 actgatccgg ctccttctac gatcaaagaa aggccttttc ctacaaaacg catcccattg
     5401 ttcccgggtt gatcgtcatc tccagccatt ttgaccgaga tttgtccacc acttgataca
     5461 tggatttgac tagaatctcc ttgcaagcga aatccgcccg tagttgctgt attgatggtg
     5521 attttcccac cattcgatac agtgactttc gatcctgaac ctctcatttg gatgattccg
     5581 cgattgttgt cattggtaat attgatcttt gtatttaccg aaaattcgct tcccgaacca
     5641 ctgacttcaa acatgacatt accaggtagc gtatcgactg cctctccttc atcgctaacg
     5701 ccatctgccc gatcataatc aagagagacc tttgaaccgc ttaagatatg gattcctggc
     5761 gctgtttttc cactaccagt ctcatctcct gaatctagaa aaccgtagaa tttccctaga
     5821 tacggtccat aaagttgact accattgatc acattcaatt gatagcttct acaaaaatag
     5881 gctttacccg gagcggcatt cagtccttcc ttcactggtt ggacatccaa cacaccggaa
     5941 acaccatcta atgtgacagt tgcacgagga gcgtaaatca gtcctaattt ggacccatca
     6001 tacaaatcaa gtgtcccggt aaattttatt tctcccgtaa aatgatatct gcttccccaa
     6061 aaatcggtca tataagcaat gataatggca tttccatcga tatttggtgt caatccacct
     6121 ggatgtgcag ctgttccttt aaaattctgg aactcgatcg actgaggtat ctcattgata
     6181 taaatatggt gtgtgccgaa attgtgagcg aatccaccaa aatcaataac gatatctcgt
     6241 ttgatctcta attccctgtc taaagtcaaa ggctgaatca gtcggatctt agttactgat
     6301 tcgtctgcga gaagctgcgc cagttcttct gttgtggcag cttcgctgta cccatccgct
     6361 gaaacagctc ttgccagtgc cgcttcactg ctatcagacg tttgttcagc tacttctgag
     6421 gtctcacttg tcttattttc ttcttgcctt ttattagtag aagcctcact ttgagattct
     6481 gtagtttcag aagtaatcga ttcttctgaa aaagtagtct tgtcaaaact ttgattctct
     6541 gattgcgttg attcgtttgt tttctctaca tcggcaaaaa cggatgtcac catcaagaga
     6601 ggg
//
LOCUS       DAFTHM010000123         6471 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFTHM010000123 DAFTHM010000000
VERSION     DAFTHM010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.123"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            1040..1558
                     /locus_tag="L7C88_002505"
     CDS             1040..1558
                     /locus_tag="L7C88_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBP9559294.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            complement(2695..3102)
                     /locus_tag="L7C88_002506"
     CDS             complement(2695..3102)
                     /locus_tag="L7C88_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBP9559295.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(3099..3332)
                     /locus_tag="L7C88_002507"
     CDS             complement(3099..3332)
                     /locus_tag="L7C88_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBP9559296.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            3666..4751
                     /gene="xerS"
                     /locus_tag="L7C88_002508"
     CDS             3666..4751
                     /gene="xerS"
                     /locus_tag="L7C88_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBP9559297.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(5035..5700)
                     /locus_tag="L7C88_002509"
     CDS             complement(5035..5700)
                     /locus_tag="L7C88_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBP9559298.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(5854..6003)
                     /locus_tag="L7C88_002510"
     CDS             complement(5854..6003)
                     /locus_tag="L7C88_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBP9559299.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            complement(5996..6205)
                     /locus_tag="L7C88_002511"
     CDS             complement(5996..6205)
                     /locus_tag="L7C88_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBP9559300.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
BASE COUNT         2219 a         1050 c          995 g         2207 t
ORIGIN      
        1 taagtggggg tagttcacta aaacatataa gttgaaatga gcagcatttt tgataaaata
       61 gtactcgtaa acgtccatac tatagacttt ttaggtactg tccgttagtg aagtttcaga
      121 ataagaaagt cataaaaatc gacaccgtgt caaccaactt aacagagtat cggttttcta
      181 taattgttta aaaagaagtt atttttttgc caaccttaaa caatctataa caccagcttg
      241 atcccttaat tttggaaaaa aatttcggaa gattaacata attattcata attttagtaa
      301 attcgcggtg aattttcttt tgcaagtgta tctgtttcat tacaccgcac cctagaagaa
      361 tatctggtga aaacatcatt gtagtattat aaatgcattg tgcaacataa aaagcttcaa
      421 tttcctaaaa aggatgatct tcaggtaaat cttgaccttt aatagttcgt cgagcgaggc
      481 gtgaatatgg caatcgcttt tttagaatta aattttcttc gagttgatca tttcgttttt
      541 gtagctgttt catctgatga gccgtaagga acgtgtcatc gtcaattttt acttcataat
      601 attttttacc caacgcgcaa tcgaagaaag agcgatgctg taatcctata taaagcattt
      661 tgagttttac cactttcgtg aagtttaaca atggattttg tgaactatcc tcacttaact
      721 aaacttaaca gttcttaacg cttaaagtgg tagtttttat tagtaattga tagtagttaa
      781 catgattttg atatttacga agaaaatgat atgcaaacca gtccgatttt actacaaaag
      841 aaatatattc gtatttttta gctccttgct gacgatcaac atttctttag atgagacgtt
      901 gggatatttt ataaatcatt cacatatgag ttagacagtc aatgcatatc agatatgcat
      961 tgtagaacgg attaaaatat cgtggatgaa attatagatg aattaaagga gacaattagg
     1021 aatttatgga ggtaatataa tgagaacata taaaaataaa gaagaattaa aaaaagaaat
     1081 aaataggact tatactaaat atattttaga atttgaaact attcctgaag aattgaagga
     1141 taaaagagtt gaggaagtgg atagaacacc tgctgaaaat ttagcatatc aagttggttg
     1201 gacgaattta attctaaaat gggaaaatga tgaaagaaat ggattatctg ttaaaacgcc
     1261 ttctgatcaa tttaaatgga atcagttagg agagttatat aagtggttta caaataccta
     1321 tgcacatcta ccattgaaag aattagagga aattctcaat cgtaatattg atgatattaa
     1381 catgatgatt gattcaatga gtgatgaaga tctattcact gcacacaaaa gaaaatgggc
     1441 agacgaggca accaaaacgg ctgtatggga agtatataaa tttattcatg taaatacagt
     1501 tgctccattt gggactttta gaacaaagat aagaaaatgg aagagattag ctttgtaaat
     1561 tcccgtttac tgctaagcaa ttgtggaaag gagacctctt gtatgttaac agtaagaaca
     1621 tacgactaca taagttcttt gctaactgcc ggtttttatt gggtgaatgc aagtgcactc
     1681 ccctagaatg ccgtagaggg tgcatcgtta gattgtatca attttggttg gccaacagat
     1741 aaaccatgac tcacttcgat aaaatgagat tatggtgcca tatccgctac aaagggactt
     1801 aggagactag caggggaaag atttttttat ttttgggatg tttttcagac cgccgatagt
     1861 accgacaatt ccctttaaat atggaatctc aacaacccac atgaagggta aggcaagtcc
     1921 ggtaattata tcttctgact ttgggttagg aagaattgaa attgttaaga acgattcaac
     1981 gcttatggtt tataatttgg agatagcctt tgttaatatg ctaaagccaa catacgatac
     2041 agattttgag cagtttattc taaccatcaa agggtatgtg gcctatcgcc tatcctatta
     2101 ctgatactga agagatctta aataaattct atacgggatt tgaagatcct gaaggtgaaa
     2161 tcgtcattta tcagaataaa taaatcaaat agtagaagtt caaagaatga ggggaacatt
     2221 agtttttatt gcttagttta atcccagtac cgatttctgc aagatgtaaa aggtctttca
     2281 tttcataagt tttcagaagc aagttcatac gcactaactc actttcgatt gagtagcaat
     2341 cgtcaacaaa ctttactatc agctgttatt tttattcttt cgtgttatct aaataccatc
     2401 aatttataag ttgtaggtgt atttaataaa agaacaaata actttagtat ttttattaat
     2461 ctaacttaca aactagtagt ataggggtaa atttgcgatt attcataaat ataccaagta
     2521 aaagtatagg gtatagtaaa aatatgataa aataaatagt cgttatctta atccaactat
     2581 atagaaaatt tacgttttct atatagttgg atttgaatta tagctatttg taatttactt
     2641 caattatttc gctatagcag ctaataaccc tataaagaca catacagtaa ctccttaaat
     2701 gggctgcgta tgtgtcttta tagtgttgat cacttcatat tttagttgat cgaaatcctt
     2761 atcatacgta gcaatatata ccgctaaatt tacagcatct ttttgatcaa tagctaaaag
     2821 ctgtccattg attttcaaaa agacaaaagt agctaagaaa gcagtacgtt tatttgcatt
     2881 gtgaaaagga tgtttcttta tcaattgtat aagtaggata gctgcttttt cataaatcga
     2941 aggataaacc tcttcaccaa aagctgaggc tcgaagttgc cctacacaca tttctaaagc
     3001 attcgcatcc tttacaccaa ggggttcatt aggagagtat ttttttattt ggattacatt
     3061 catttttata atatctttgg cttctaggta atgaatactc atttatcgac aagctctcta
     3121 aaagtagtat catattcagt taatgcttga gatattgcta aatcaatttc atcagataag
     3181 gcttgttttt ttgtaattgc cgctcgaagt ttttcttcat ctaaaaaaac cgtatctccg
     3241 ggatttaacc cattttcttt aagaaactcc tttgaaatag ttaatactac tgagttcccc
     3301 acttccctaa attttctttc tttaattgcc atagtcttct ccctcctttt tctttgtata
     3361 tacagtatat acgcttgttg attttaaatc aagcatagtc cctctcatgt ctaactctat
     3421 agaaagattg ttctttctat ataattaatt aagaaaattc aaaaaattta gattgctccc
     3481 ttctatttcc ttccctattt atgtatacca tttattttaa attattaaac gtatacctgt
     3541 ttatatgctt tttttgaaac aaattaataa attttagagc ataccaattg acaaaacatt
     3601 ctataattgg tatagtccaa ttatagagat actcttctcc cctacttatt gaaaggatga
     3661 atgacatgaa aaatacagaa atatatcaaa aaatagatac aatcatactt catatgcccg
     3721 attatataaa agattttgtt caagatcgtg aggataaaga tcaatcacct cgaaccactt
     3781 tagaatatct aaaaaattat aagctctttt atgaatggct tctgagtgag tctatcgttc
     3841 ctgatacttc tatcacctcg ataagacagt taactgccta tgacctaaac ttgtacaaat
     3901 ctcatttgaa acgtcgcaca aaagaaaatg taaaaaaaga gacaacaaaa actaagctca
     3961 aagataataa taacttaggt ctatctactt ctactatcaa tagaaatatc acggcattaa
     4021 aggttctatt taaatatctt tcgaaaagtt ccaataatcc tctaggaaaa ccatacttag
     4081 acaataatcc tatggatcaa gtagcaacca tcacagataa aactacgtta gctgcacgtg
     4141 ccaatgccat tgagaaaaaa ttatttctag ataaggatac acaaaattat ctagattata
     4201 ttgccaatga atataaaaat actttgagta aacgagcttt gatctattat caacgagatg
     4261 tagaaagaga cctggcgatc aatgcactga ttttaggatc tggattgaga ctctccgagg
     4321 ttataaatat taatttagat gacctatctt tagataagaa taatgtggta gtaactagaa
     4381 aaggaaataa aagagatgct gtcaatatag cagcattcgc aatggaatat ttagctaatt
     4441 atctagctat tcggaaagaa cgatataaag taacagaaaa cgaaaaagct ttatttctag
     4501 caatttacca aggagaagcc aagcgtatat ccggtattgc aatcgaacgg atggtagcaa
     4561 aatattcaaa aggctttaga attcaagtca gccctcacaa actgcgtcat acattagcta
     4621 ctagactcta ccaacagaca aattcattgg tattaactgc ccaacaattg ggacattcaa
     4681 gtaccaatac aacaacttta tatacccata tagacaatgc ggctacgatc gatgcattaa
     4741 atgctttatg agtataatgt ataaataggc ggaaataaga aacaacacgc tagaaaagcc
     4801 tgtattatag tttttctagt gtgtttcttt tggtgtgatc ctacttttgt ttatcattta
     4861 ttttttatta tcgtaaatag gtgtcggttt gattttagaa aaattagttt ggatataatc
     4921 tgtgggatca tttgttatct ctctcaatga atttagatac aaatgaccat aagttcctaa
     4981 agtcgtttgt acatcagcat gttttaacct ttctttaatt cgaagtgcat ctttttattg
     5041 tgatataagc aaagaagcat gactatgcct taatccgtgt atgcggatta tatgaacacc
     5101 aacgatcgtt gcatgtcttc tcataatatg acggattgta tatttctgag taggtgttcc
     5161 attataagaa agtacaaacg acatgcctcc tattgaaact tgacgctcct tccaagcttt
     5221 taaaaaggta attgtattgt cgtctagttc gattgtacga atactagaag ccgtttcggg
     5281 ttctacaaac tcataggttt tggctctctt ataatagagt gttttattca cacgcaagtt
     5341 tttattttca aaatcaatat ctttccaagt taatgcagtg gcttctccca aacgcataac
     5401 ggtcataaaa agtaaccaca tacaaataaa accaaaatgt tggtacaaat catcaatata
     5461 aaaagttgaa ataacttttg taaattcttc ttttgtccaa aaatcaactg tagttttcct
     5521 tttcttcaca tttccaataa cttttgcagg atttttttca agtagtccca aaacaactgc
     5581 tcgatctaat gacatctgaa aaatcccata catgtttctt acataagaat ttttatattt
     5641 gctcaataaa ttattttgcc acttttgaat gtcaattgga cgtatttctc ttaactccat
     5701 tttaaagaaa taagaaaagt ttttttgatt gtagataacc gatttttata tgttctttct
     5761 tctactttcc cttgataata aggtaggaat aatttataaa aaaactcctc aaacaacata
     5821 gtactttgag aagtttctgc ttcttttcca taattagaaa caagttcggt atacgctttt
     5881 tttcttcttt aactgtttta acccctctac gtttttttgt actcttttcc ctgttcgttt
     5941 gtcgaatccc aaactagcag taaaatgata tttcccattt ttatcttttt taaaattaac
     6001 catgattctg aaaatcctcc tctacctcta tcttcatacc taaaacttct tctacagatt
     6061 caacaggtac tagtcctaat cttctatttt cgtaataggt atagcttttt gaaaccataa
     6121 ttgcttttgc ctgtcgtatg attctctcag actgatactt cccataacct aatttcatta
     6181 attcattttt tgttataacc accatttaac caccacattt tttattcaaa tataaaaaag
     6241 aacactacta aaaatagtag cgttcctgca tatttttatt caaatttaat cagctttata
     6301 aatctttgta tacttgctcc ttaatactca aaaaatgcac attagaaatc taattctaaa
     6361 aaatatcact agtgttgcat aaaacatttt agaatattct gaaaactatt tcctctgaaa
     6421 ataagtcaaa aaaaactgtg ctgacgcaga ggatgacttt ttccagaaaa t
//
LOCUS       DAFTHM010000124         6303 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFTHM010000124 DAFTHM010000000
VERSION     DAFTHM010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.124"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            334..714
                     /locus_tag="L7C88_002512"
     CDS             334..714
                     /locus_tag="L7C88_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBP9559301.1"
                     /translation="MSEQHQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPD
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            696..1610
                     /locus_tag="L7C88_002513"
     CDS             696..1610
                     /locus_tag="L7C88_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBP9559302.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     TLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPNHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKTEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYTQFCDSLKTFGIHCLNRGKNFTYELVHKKK
                     KVRSNKLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTFTP
                     EQSEIRPTRRNHEQHVERGTDHQQELSL"
     gene            1855..2544
                     /locus_tag="L7C88_002514"
     CDS             1855..2544
                     /locus_tag="L7C88_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559303.1"
                     /translation="MAFYLPYLLISASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLV
                     GVIFALSIVLSGLFGVLEGNKRVSRSILLGDITQKYEAACDKKKKEQALAQKMEEFTA
                     CYEDMNNIFVDQEKRLTDKNMKKLTRFYQNLPEKQQKEVQEKYEQVKKDVQYFKDTQT
                     EEACCNLFSDTIPFSTSEQERKERQQSVTYERYETLLQQATNIQNPTKKETALNYLES
                     VKEWLDQQQQN"
     gene            complement(2665..2751)
                     /locus_tag="L7C88_002515"
     CDS             complement(2665..2751)
                     /locus_tag="L7C88_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBP9559304.1"
                     /translation="MFERFICPLLVEVCVSLFSYWLNNRNKK"
     gene            3427..4377
                     /locus_tag="L7C88_002516"
     CDS             3427..4377
                     /locus_tag="L7C88_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HBP9559305.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     LTFDQLKDLSNYKATANNRFINDLEMTYDKLMDLRFGKRSANGLDIDRFVMFSEFKIR
                     GTAKDPYVDIQVYEKALPLLNNLDEWVRYSLQQFNELQSSYAKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYWNNQANVDNRVIKPIRQELTAIFKGLSIKKKYGKGRGKPVV
                     GYQFTFKPEIKKADDFNKHAPTKEEQNKALALADKQKEYEEPATTINEKIKQKKRELE
                     LLQQIKQLEKEKEALEKQTESALSKKEKKSLLSDLDNLFQ"
     gene            4398..4931
                     /locus_tag="L7C88_002517"
     CDS             4398..4931
                     /locus_tag="L7C88_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBP9559306.1"
                     /translation="MQPQETFTIKELSELFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLGNQMLLDRLHEYEQDNDKNVNIPSKNVVTNKLLDQLREENEFLRE
                     QLALREQNNSHIQKLLDQQQQLTLQANKQIEKLQEKLQLTYTEEAPENDSTTLSEATE
                     TIDKQIDTEKKWWQLWK"
     gene            4947..5117
                     /locus_tag="L7C88_002518"
     CDS             4947..5117
                     /locus_tag="L7C88_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559307.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            5567..6100
                     /locus_tag="L7C88_002519"
     CDS             5567..6100
                     /locus_tag="L7C88_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559308.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
BASE COUNT         2323 a         1102 c         1174 g         1704 t
ORIGIN      
        1 aaaaaaaaat aaatcgatac attttagaag aatagggttg tttgaatatt acaaagcaac
       61 aatttcacct tcggtgaaat aagcgaaact ttacaaaaag tggctagcaa atgctagcct
      121 ttttttgtat tgtggagcgt ggattttgag ggggattcaa gggggagctt gcgctccttt
      181 gacaagcggt tatttgcacc aaatacggag gtatttggct agcaaatata gagcttgcca
      241 aaccctttta gtgagcttta ctcattgtac ctttttaggt acaatggtat tgcgaacgat
      301 acgtccgtag gacgtactga aagggtggga cttatgagcg aacaacatca aaatttggct
      361 agcgatcatt ctaaaaaata tacctatcga tccgagccaa aacaaatcag ttttcgagtg
      421 agcgaatccg aatttgcaaa gctgaagcag tcagctgaag ctttgcaaat gagtgtgccg
      481 gctttcgtga aagccaaggc acaaaacgcg cgtctggtga caccgaaagt ggcgccagac
      541 attgcccagg caatcgcgcg cgatttagcc aaagctggag ggaatatcaa tcaaattgcc
      601 aagtggtgca atacacacca acacgacgtt gctcctgatg atgctcaacg tttatccgaa
      661 aacctaaaaa tcatgcaaaa ggagctacaa aagatatggc aacagttaaa gtaagtcgaa
      721 ccacttcatg tagccgagca atcaattacg cagaaccacg agcaaccgtc aaaacaggaa
      781 taaactgtga cattgattat gccaaaagtg aaatgaaaca aatacgcacg ctttatggaa
      841 aagacgatcg tgtacaagca cacttattga ttcagtcctt tcgaccagga gaaattaccg
      901 ctgaaaaagc caatcaacta ggggcagagt atgcgaaaaa aatagcccct aaccaccaaa
      961 tcgcgattta cacacataca gacaaagacc atattcataa tcacattgtc attaactccg
     1021 ttaatcttga aactgggaaa aaatttcaag cccatgggca agcattttta aacaaatgtt
     1081 atgacctaaa tgacgagatt tgtcttgaac atgacttaac aatcacggaa cgaggaaaga
     1141 aaaccgaaaa acgaaccatg tctgaaatta aattaaaaga aaaaaatgaa ccggtttgga
     1201 aagacgaaat tcggtttgcg attgatcaaa caatgaaaaa caaaaaaact cgaacgtata
     1261 cccaattttg tgattcactt aaaacattcg gcattcattg cttgaatcgc ggaaaaaatt
     1321 ttacttacga attggtccac aaaaagaaaa aagtacgatc caacaaacta ggaaaggatt
     1381 acgaaaagga gacgatttta catgagctgg acagacgaga acgaacctac aatcaacaac
     1441 gaaccaacga gctacgaaga gctcgagcta gcattcgcga aactgcagaa gaagtacgaa
     1501 gagaacaacg aacttttacg cctgaacaat cggaaattag accgactcga agaaaccatg
     1561 aacaacacgt tgaacgagga acagaccacc aacaagaatt atcgctctaa aacgttaaaa
     1621 gacatcgaaa acgaaataaa gagacaacgt gcctttcttg cgccttatac ccaagaaagg
     1681 atacaaacta cgatggattc acaagtcaaa aaactccacc aagcgctatt agaccagcga
     1741 aaccaagaac aaaaaaaggc tttaattcaa cgatcgatgg atattcttgc ccccttatgt
     1801 tgcttagtac taacattatt agccttttgg ttggtatggg gagaataaac agacatggca
     1861 ttctatttac cctatctact catttctgcc agtattttag gaattatttg gcttagctat
     1921 aaggcttatc aaacaagata ttcattaaaa ggctctaaaa ttcgatttaa gcgattttta
     1981 ttggtcgggg ttatatttgc cttatcaatc gttttaagtg gtttattcgg cgttttagag
     2041 ggtaataaac gtgtttcaag aagcatttta ttaggggata tcactcaaaa gtatgaagca
     2101 gcatgtgata aaaagaaaaa agagcaagca ttagcacaaa aaatggagga atttaccgct
     2161 tgttatgagg acatgaacaa tatttttgtg gatcaagaga aacgtttaac agataaaaac
     2221 atgaaaaaac tcactcgttt ttatcaaaac ttaccagaaa aacagcaaaa agaggtacaa
     2281 gaaaaatatg agcaagtaaa aaaagacgtg caatatttta aagatacgca gacagaagaa
     2341 gcttgttgta acttatttag cgatacaatc cctttttcaa ccagtgaaca agaacgaaaa
     2401 gaacggcaac aatcggtcac atacgaacgt tatgaaacac tgcttcagca agcaacaaac
     2461 atacaaaatc caacgaaaaa agaaacggca ttaaattatc tagaaagtgt caaggaatgg
     2521 ttggatcagc aacaacaaaa ttgaatttga ttagcaatca tgttaaactg aacctgcaaa
     2581 tgatcaaaca ttagatacac gaaagcccca gagaggtcgg attctctggg gctttttttc
     2641 aggttgatgt cgcctttatt gattttactt cttgtttcgg ttattcaacc aataactgaa
     2701 taaagagaca caaacttcta caagaagggg gcaaatgaac cgttcaaaca ttagatacac
     2761 ctccttccag tcgcaagact gtcggatagg cgacaagtta ttatacctta caaaataaaa
     2821 tctgtgtggt gtttttaagt atcccttatt ttcgggttgt tagggcttgc cctgaccgcc
     2881 tgtaaggcgc tttaagaaca agataaggtt ttttacccaa gactgtctta aaacgactta
     2941 gacgagctat cagaggcttc ccccacctcc gttactgact tgtttttagc aaaggagcct
     3001 ttaggcgact gcgcagtaca atgtgagagc atagcgatca cactttttta gcgaccgtag
     3061 ggagcaaggt tttgaattgg cagttttgaa aaatgcgcga acctgttggt agaaaaaaga
     3121 agtggttttt aggcgggaaa ttttgtcacc ctcttttata atctcttttt aaaccttttt
     3181 ttaaacctct ttaccgtcgg ctgtgtcctt actccttcaa tggatacagc gttttataaa
     3241 ctacattttg tctgctttta aactacattt tgtctgcttt taaactacat tttgtctgct
     3301 tttaaactac attttgtctg cttttaaact ctttttttgc actcacgtat gttataatat
     3361 gcattatcac agacaaaacg ttgtttataa cgtctgtatc cattgaagga gtaaggagga
     3421 atatctttgg caaatgaaat cgtgaaatac catcatgaat taaataccat tccgttgcgg
     3481 aaatttacac cagttgaaat gaatctattt ttctctattg tgtctagaat gcgcgaaaaa
     3541 ggcgataaaa cagtccgtct tacttttgac caactaaaag atttaagtaa ttataaagca
     3601 actgctaata atcgtttcat taatgattta gaaatgactt atgataaatt aatggattta
     3661 cgttttggta aaagaagtgc taatgggctc gatatagata gattcgttat gtttagtgag
     3721 tttaaaatac gtggaactgc taaagatcca tatgtagaca tacaagttta cgaaaaagct
     3781 ttacctttac taaacaattt agatgagtgg gttcgctatt cactccaaca atttaacgaa
     3841 ttacaaagta gctatgcaaa gactatgttt cgattactaa aacaatatcg aactaaaggt
     3901 tttgcttatt tttctaaaga ggattttcat gaactattag atattccaaa aagttactgg
     3961 aacaaccaag caaacgttga taatcgtgtt ataaagccta tacgacagga attaaccgca
     4021 atcttcaaag gattatcaat caaaaagaaa tacggaaaag ggcgaggaaa acctgtcgtt
     4081 ggctatcaat ttacgtttaa accagaaatc aaaaaagcag atgattttaa taaacatgca
     4141 ccaaccaaag aagaacaaaa taaagcattg gctttagctg ataaacaaaa agaatacgaa
     4201 gaacctgcta caacaattaa cgaaaaaatc aaacagaaga aacgagaact tgaactcctc
     4261 caacaaatca aacaactaga aaaagagaaa gaagctcttg aaaaacaaac agagtccgca
     4321 ctttcgaaaa aagagaaaaa aagtttatta tctgatttag ataatttatt ccagtagcaa
     4381 cctaggaggc aaccagtatg caaccacaag aaacctttac aataaaggaa ttgtcagaac
     4441 tttttaagat gagtaggcaa gcaatatcga aacatatcca aaaattagat tcttccatga
     4501 tagctaaaaa tgagcgtggt tataaggttg tattgcgttc tggagtattg caacttgctc
     4561 gcaacttagg caaccaaatg ttgctagata ggttgcacga gtacgaacaa gacaacgata
     4621 aaaatgttaa tataccaagc aaaaacgtgg ttacaaacaa gttgctagat cagttgcgtg
     4681 aagaaaatga atttttacga gaacaacttg ccctcagaga gcaaaataat tctcatatac
     4741 aaaaactact cgaccagcaa caacaactca ccctacaagc caacaaacaa atcgaaaaac
     4801 tgcaagaaaa actacagttg acttatacag aagaagctcc agagaatgac tcaacgactc
     4861 tttctgaagc aacagaaaca atagacaaac aaattgatac tgaaaaaaaa tggtggcaac
     4921 tttggaaata actggaggga acattcatga caagaaaaaa tcttctattc ggttctattt
     4981 tactaggaat tctaggattc agtccgatgt tattgtcagt gatcaataaa gggaataaac
     5041 atggtgaatt gaaattgaat ccaaattatt acaacagtcc taacgaagaa ttgtttgtaa
     5101 aagaaacaga taaataataa aaaagactgc tctttcgagc agccagttaa aaaataatga
     5161 gtgtttattc ttgaaaaagc aacgcgctta tgaagcgcta ccaaaaattt atcatatttt
     5221 attaaaaata acaacccagt aaaaaatgac tggtaaaaat tcacaaagaa acggaaagaa
     5281 gcaaccgcag aaaatcaagc ttaaaaagag cttttgacct agaccaatcg aaaatcacaa
     5341 agtgagcgcc tgtatctatt gctacaggcg ctacttggca tagtgtacat tatgtcaaca
     5401 agaatttaat ataacatatt ttcctaatgc attctaacta taccacatta tcaaaaatat
     5461 aaattatctt tactaaataa aatattgaca agcctatacc ttttgtttta tgattttcac
     5521 aaagaaaacg ttttctatat atttttctgt atcaggagga aattctatga aaaaatttac
     5581 tttaggggta gctttgttaa ctattggggc agttgtttta ccgtcaacta ctatagttta
     5641 tgcttcagaa aattcccaag tggtatcatt aaacgaaaac aatgctactg aaaatgtagt
     5701 tattgagtac actgaagatg gtatggtcgt aactaaatat gaggatggtt atagtgcgga
     5761 agattttgca aattcttcag atatcatgac aagagctgca gttgcaagat ggggcaaaaa
     5821 ggaatataca aatattgctg taaccactgg agtagctgct aatgctatta atgctgcctt
     5881 ttgggcagga gggaaagcta gcacttctat gtttggtatc ccaggttggg caattggtgc
     5941 tttgttaaca ggtgcaagtt ggactaaaaa aggtgcttct ccagggaatg cagttgcaaa
     6001 agaatgggac aaaaatggta atggctggat tggattttat taccaaaggg gatatgatgc
     6061 agctggaaga gttgtagcta ctagatattc aacgttataa gttaaggagt gatgtttttg
     6121 atatctaaat cattaaaatc attaaaaaca tttactaaaa agaatccgca aatagctact
     6181 attcgtattt ttatatttgc tatagctgtt gctataattg ttaatatgct aagcggaggg
     6241 caattataca aatctggttt atttttagtg ttaatcttag ttgtcttaga cataataaag
     6301 tct
//
LOCUS       DAFTHM010000125         6287 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFTHM010000125 DAFTHM010000000
VERSION     DAFTHM010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.125"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..177
                     /locus_tag="L7C88_002520"
     CDS             <1..177
                     /locus_tag="L7C88_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559309.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="L7C88_002521"
     CDS             190..690
                     /locus_tag="L7C88_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBP9559310.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="L7C88_002522"
     CDS             787..2634
                     /locus_tag="L7C88_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBP9559311.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="L7C88_002523"
     CDS             2637..3533
                     /locus_tag="L7C88_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9559312.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="L7C88_002524"
     CDS             3583..3972
                     /locus_tag="L7C88_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBP9559313.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>6287
                     /locus_tag="L7C88_002525"
     CDS             3959..>6287
                     /locus_tag="L7C88_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBP9559314.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2118 a          933 c         1348 g         1888 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatctctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccgg
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagatgcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac cctcaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
     5461 ggagcgagga gggtggaaag aaaccttgcc agaaattgcg gatgaaatca gtatcctcaa
     5521 cttgacgagt aagtcagaaa atcaaggtct gcttgatcct tatgtgatta tgaagaaaaa
     5581 gaaagactcg gaaagtttag caattgatat tctgactttt ttaacaggaa tttcaagtcg
     5641 agacggggag aagtttcctg tgttacgtaa agccattcga acggtgactc aaagtgatca
     5701 acgggggtta ttacaagtta ttaacgaatt gcgaaaagac gggtcaccaa tcgcggaaaa
     5761 tatcgccgat catatcgagt cctttaccga ttatgatttt gctcatttgc ttttctcaga
     5821 cggctcgatt acccaatcga ttagtttaga taaacagcta aatatcattc aagtggcgga
     5881 tttggtttta ccggatgcag aaacgacttt tgaagaatat accaccatgg aattgcttag
     5941 tgtttcgatg ctaatcgtca tttccacttt tgccttggac tttatccata gtaaccgaga
     6001 aatcttcaaa attgtcgatt tggatgaggc ttggagtttt cttcaagtgg ctcaaggaaa
     6061 aacgttatcg aataagcttg ttcgtgctgg tcgggccatg aatgctgggg tctatttcgt
     6121 cactcaaaat agcgacgatt tattagatga acgtttaaaa aataatatcg ggttgaagtt
     6181 tgcttttcgc agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggtttgga
     6241 tcaggaggat caaagcaatc aaaaacgcct gcgagatttg gaaaacg
//
LOCUS       DAFTHM010000126         6257 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFTHM010000126 DAFTHM010000000
VERSION     DAFTHM010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.126"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..1911)
                     /locus_tag="L7C88_002526"
     CDS             complement(<1..1911)
                     /locus_tag="L7C88_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBP9559315.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILK"
     gene            complement(2123..3019)
                     /locus_tag="L7C88_002527"
     CDS             complement(2123..3019)
                     /locus_tag="L7C88_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBP9559316.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(3012..3692)
                     /locus_tag="L7C88_002528"
     CDS             complement(3012..3692)
                     /locus_tag="L7C88_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9559317.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(3693..4475)
                     /locus_tag="L7C88_002529"
     CDS             complement(3693..4475)
                     /locus_tag="L7C88_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9559318.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(4468..5385)
                     /locus_tag="L7C88_002530"
     CDS             complement(4468..5385)
                     /locus_tag="L7C88_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBP9559319.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(5549..5872)
                     /locus_tag="L7C88_002531"
     CDS             complement(5549..5872)
                     /locus_tag="L7C88_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559320.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
BASE COUNT         1862 a         1273 c         1003 g         2119 t
ORIGIN      
        1 tttcaatata taaactaatt tttcaaacga cgaactcgtt tttaaatttg ctaataactc
       61 atgattcgaa gcgatttcat tgaatgtttc ataaatttta ttcaattcag gttttacttt
      121 ttcattaagt gcaaaaaaga aaacagaatg aacaagtgtc ccatcccaat caattccttc
      181 tggattaacg tagacacaga ttactggctt ttttataaaa tctacttcga tatgcggcat
      241 agcaaaatca ttcatcgctg ttgaagatag tttttctctt ttgattgctc cctctagtat
      301 cccttctttc gcgtaatttt cttttaccaa ttttttggta attatattta aaacgttcac
      361 ttgattatcc tttatttggt gggtaaaaaa gcaaaatcgt ttatctaata aatttagaaa
      421 agcatcttct gtttgttcat ttaactgtag atactgtttt acttttctga catctgcccc
      481 taacatcaaa ggactaacaa caataacagg aaaatttgta ttttcaatcg gaatcgtgct
      541 tataacaagt tcatcagtga cttttctatc ttgtagttca ttgatgctta gtacatcttc
      601 tatctcaacc atatctgcaa aaccgttatt tattctttgc tctaataatt ttgatgttcc
      661 atatccgcta ctacaaacta atatcacttt cgttttgtca ggtttgtaac gatccaaaag
      721 tgattgaata tggagtgtta cgtaagcgat ttcatcttca ttaaaatgta tacagaatct
      781 ctcttcgatt tcctctaata aatctacact tatcataaat gaccttttaa aagaatattt
      841 gattttgtcc gtataagggt tatagatatt tactcccaat ttgagtcttt taactgctgc
      901 attgagatgt aatactagat tattgatcaa ttcttcatca ggataaaatt catttaattt
      961 aattcttact aactcttgta gctcaacacc catatctaaa taggaaagct tcgtttgatc
     1021 taagtcgtga ttcatagcat ttttttcaat cgaagtaatg tgaatgtcaa cataagcttg
     1081 ttcatctatt ggcacaataa ttgaaaatgc tttttcaatc attttgatta aaataagtgt
     1141 attctttgag atttcttctt cagaattatt actacgtgat aagaaattgc ttgtttcaat
     1201 cctttctatc gcaatagcaa ggtggatagc taaagtttga aattcataat ctgtaaattt
     1261 caattgtgtc ttattcatgt atcgattaag caattcggct acttttttca atatgtcctt
     1321 atttaagaaa ttattcgctt caccaatgaa attgatattc aagtctaaga gatctgtttt
     1381 actgttagat gctgtaaagc caccccaata atagttcaca acttctgaca tcaaccttct
     1441 tttacttttt tcatcagctt tgatgcgcac gccatttcga tctgaaacta aggacatccc
     1501 atgcttgttt agtctttttc taacatcttt cattgtgctt tctaccgtcg acctgctcac
     1561 gtataattcg tcagcaagat tttgaatctt tagagaatca ttagtattca ataatttagc
     1621 aaacacataa gttagacggt cctccggaga gtctgcgata ttgattttat gactggataa
     1681 taaatttcga agtgtttctt tttttccaat aagcgaaacg ccttttttag gttgaaccaa
     1741 catttgtaca tctggcattt tttggattat ttctttcaaa attaaaatat ctttgctaat
     1801 tgttttcgta gatacatata attgttctga taattctttg taagttgtgt gctcattttc
     1861 aatcaaaaag tatagtattt tcatttgccg ttcgctaaat tcgatgccca ttatcttcac
     1921 ctcctgaata cagcttaagt gtacaattat tatctctatt ttcatacaga agaaagttct
     1981 tgattaatgt agaagtttct aatattcttg attatttcaa atcaataaaa aagcctgcaa
     2041 tatttatatc acaggctttt ttctctatta aatatatata agataataca tttttctact
     2101 agttctcact aatcttgtat aattaaaccc tccgcaactt gacggagatg gagaagatgc
     2161 ccccgtctaa tctagcggtc atctctcctc ccattccttc caccaatttt tttgacaggt
     2221 aaagcccgat tccgctagat tccgtatttg tgcggctggt attttcggta taaaaacgct
     2281 ggaagacttt ttcaacagag gtttgcgttc ctggtttgat aggattggcc actgttaatc
     2341 gaatgaatgg atcctctttt gaaaatgtca cctttgcttg tccatctgca taacgcaata
     2401 aattctgtat gatattttgc agcactcgca gcaacatgag cggatctgct aatacagttg
     2461 tatttatcga gtgttcagcg aacgctacct cgatattttt ctcagaaaat tgttcataaa
     2521 aagagaaaaa tacttcttcc acctctttag aaaaagaaag cgtatggaga tccatttctt
     2581 tttgcttcgt ctctattcga gcaagatcat aaaactgatc cgtcatactg agtaatcttg
     2641 caacagattg tttgatgatc gttaaatact tctcccgttt ctccgtatcc tctacctgtt
     2701 ccagtaattg tacataaccg ttaatagcag tcaaaggagt tctgagatca tgagaaaggc
     2761 cgacgatcga tagtctgatg ttttcttcca tttcttgaaa tgcttgtcct ttttgttcat
     2821 tttcatccaa ccatgtattc agtgcatcta ctaggtccat tagattcttt tctcgaaatt
     2881 cgactgaaag acgaccacca tattcttgtc gttcagaaag agtggcgatt ttcttagtta
     2941 atctcttgat ttccctttgc aggaagaaaa taaaacttcc cataaagata acaacgagaa
     3001 gcaacagcca tttaatcaaa tctaaacccc actccccaca ccgtatgaat atacacagca
     3061 tgtgcctttg ctagcttccc tcgaagattg gaaatatgca tattcactgt tttctcacta
     3121 tcaaaatatg gttcttgcca aactgtttca taaagatttg ctcgcgaaaa tacttttttc
     3181 ggatgttcta aaaaaagctt cagcagatcg aattctcttc ctgtcaaatg gacagccaca
     3241 ccattcacat ttacatccct cgactctttg tccagtaaga tttccttgta atagatgcgt
     3301 tgcgacagat cttttacttg gacagaagtc tgatgacgaa gttggatgcc gattcgtaac
     3361 aaaagttctt cgatatcaaa tggtttcgtc acatagtcat ccgctcctgc tgccaacaag
     3421 gaaactttat ctctttgatc gctttttgct gaaagaacga tgatcggaac attcgatgtc
     3481 tgtcggattt ctgctaacaa tgcttcacct gaaagccctg gaagcatgag atctagaagg
     3541 atcaaatcga caggatatgt gcttaacaat aattttcctt ccgtacctga ataagcatca
     3601 agaagtttgt atctctgttc aagaacctcc tccagtaagg aatgaacagc ttcatcgtct
     3661 tcgataatca aaatagtttc cagcaggacc acctacttaa tgtcagattt ttggaaaata
     3721 aacattccta gagctgatga taccacgatt gttactagac tgaccagaat cattttcggt
     3781 gcttgcgaat aagttgcttg ttgcgcaaag tccgtataca tgagccacgt ttccgtaaac
     3841 cactccgtta gaaattccaa gcctttgatt tttgcgaaaa caccgggaat gaaggccgtt
     3901 cccatgatat aaagaaaaga aagaagcaaa ctgacactgg tacttctagt gatgaatgtc
     3961 aaagccactg gaacagataa tgtccctaat gtcagcagaa gcaatacagg aaatactttt
     4021 agaacataat ttccatagtt tttgattccc tcaacttcac caaatccgaa agcaagtgtg
     4081 taagcaagca tggctagtcc cgtgatcaaa accacgccaa gtgttgtgat caaaagcgta
     4141 acgagaagtt tcgacacata ataagtcatt cgattccgtc ctaaagataa cgtattgcga
     4201 atcgtaccgt tttgaaattc ttccccaata taaaagcacg caaatgctgc gaaagccaga
     4261 agaatccatg cagccatttt ttctaccatt aaaatccctg ttgcaccgtt gatgactgta
     4321 tccgttgctt ggtttaattc attgccgtat tttgtatgca tataccattc gttccaagaa
     4381 taaaaaagcg gaagtacgac catcagtcct agtgagaccc acattttacg gctcttccat
     4441 acttttattt tttcagcagt taatagatta aacatgtgga ttgcctccag ttaattgtaa
     4501 gaaataatct tccagttttt gcccaactag gtgaatacca tccacaggaa cttttgcttc
     4561 taccaatgct tgattgatgg ctgctacttg gtcaattcct tcaaaaagct ggataacacg
     4621 gctagattgt acaaaataat ccctataacc aagagagtcg agaaccgtta ctgcttgttc
     4681 cgtcgccgaa gtgtcaattt ttataaattg acgagattct tgtgccaatt cttctttcga
     4741 taattctttg atcaagtgtc cttcatgcaa aataccatag tgagtggcga tctgtgacaa
     4801 ttcatctagc aagtggctag aaagcaagac ggtgatgccc cgttctttta ccaaacgttg
     4861 gatgatttct cgcatttctg ccatccctgc tggatccatc ccattcgtcg gttcatccaa
     4921 aatcaaaaat tctggattcg tgatcagtgc atttgcaata gctaaacgct ggcgcatacc
     4981 taaagagaaa ttctttgctt tctttttccc tgtattttcc aatcgcatca ttttcagcag
     5041 gtcttcgatt tctctatccg acacaccgcc gttcgctgct tggatacgta ggttatctct
     5101 tgcagttaat tctggataaa gagcaggggt ttcaatcgat tgacccatac gtcgtcttgc
     5161 tgcctgcaaa tccgtcgttc caaataattc gatcgaacct tcatcaatcg agatcaaacc
     5221 cataatagtt ctcataaagg tagacttacc cgctccattt tccccaatca atccatagat
     5281 cattccacgt ttgatttcga ttgatacttt atctaatgct ttggcagcac cgtatttttt
     5341 ggttatacca gttgctttca agaccgtttc atttccaaaa tccatactta tccttctttc
     5401 ttattgatga gtgaagtata gttgacgggt ataaagaaag cagccagaaa tgtataaaga
     5461 aagtgtaaat tttccaattg aatgtcaaaa aaaacaatcg gacaatacgt gtctttccta
     5521 ttatcaggca gtttgttata cgcttgtatc agtttcctga ttctttcttt tcgaccaaag
     5581 tcgtttctct gtattcctct tcactgaaaa tttttgcttc tttcagatca agcttgagta
     5641 attttaccag accggttata aggataacta tagcaagact ccctcccaga aaaattagac
     5701 tgtctcgcag acgtggttgc gttgtcttcc aatcaaagag cgcaccaaac agtgctaatc
     5761 caagtggact ggccaccatg gtaatcgttg ttatcgttga cataagtcgt ccttgtatat
     5821 gcgttggaac ttctcgctga agccagacca tataaaaagc aaaagaaaac attaatcctt
     5881 aaaaacggac ttatgaaaaa taatacatgc cgtttgggat ttacaattag ctaccaaata
     5941 agaggttatg acaaaagact tttcacaatc ccttcttccg aataaacggt gttctcctgc
     6001 caactcctcg gtcacaagtc acaatattta tcaaacatga gaagcaattt ttgtaaattc
     6061 cttcttattt cttgaagctg accacttctg tcacaacctc agaagcggat aaataatatt
     6121 gtttgatgat actttatctt tttcccgttt gtttatagat cgaatgatat tatagaccaa
     6181 gaatcctacc tattaacata gctaaaaaca caaaaaaggc actttccaaa ttgtggaaag
     6241 tgccagaaaa gttagga
//
LOCUS       DAFTHM010000127         6159 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFTHM010000127 DAFTHM010000000
VERSION     DAFTHM010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.127"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..382
                     /locus_tag="L7C88_002532"
     CDS             <1..382
                     /locus_tag="L7C88_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphogluconate aldolase"
                     /protein_id="HBP9559321.1"
                     /translation="NSLRYLEFREGAFDFQTSQQNLLTIPGAMSPTEIFKMFEMGADI
                     VKVFPANCLGPEYFNQVQAPLGSLPLMAVGGVDQTNAQNYLNNGASYVGIGSKFFEKS
                     AVHQLNYERLMELAESFIDSLRVE"
     gene            complement(776..1783)
                     /locus_tag="L7C88_002533"
     CDS             complement(776..1783)
                     /locus_tag="L7C88_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9559322.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLTVRKSFIPKEE
                     V"
     gene            2250..3656
                     /gene="lacG"
                     /locus_tag="L7C88_002534"
     CDS             2250..3656
                     /gene="lacG"
                     /locus_tag="L7C88_002534"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBP9559323.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            3679..4002
                     /locus_tag="L7C88_002535"
     CDS             3679..4002
                     /locus_tag="L7C88_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBP9559324.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVREGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLRELINDFVELYKE
                     KFAKA"
     gene            4013..5695
                     /locus_tag="L7C88_002536"
     CDS             4013..5695
                     /locus_tag="L7C88_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBP9559325.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVVATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFS
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
BASE COUNT         1964 a          931 c         1242 g         2022 t
ORIGIN      
        1 taacagccta agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca
       61 gaaccttcta acaattcctg gggccatgtc gcccacagag atattcaaaa tgtttgagat
      121 gggtgctgat attgttaagg tgttccccgc caactgtctt ggaccggaat atttcaatca
      181 agtgcaagcc cctttaggaa gtttaccttt gatggctgta ggaggggtag atcagactaa
      241 tgcacaaaac tatttgaaca atggagcctc ttatgtagga attggttcaa aattttttga
      301 aaaaagtgct gttcaccaac taaattacga gaggctaatg gagttggctg aatcttttat
      361 agatagttta agagttgaat agaacccatt tgcggaatac aacttgtttt ataatatggc
      421 gttatctgta taaaacatag tatcacagtg aatgagattg aactggtaga ttgatttttc
      481 gaccagttct ttttgcgcgc tctgatgctt gatatattcc caacgagata aaaaatcccc
      541 caagatacta agatgaagcg tttatccaac ctcatactta gataaaaagg aggaaatgtt
      601 ctgaatgata aacaaaaatt agcgcgcaca atttggcgat gaaaaaatca tattgtattt
      661 acgtcaaaat atcaccatca aattatttat ggaaaacata ataggcataa acccgattgc
      721 tcggctacta tgtggacaca attatagttt taaagataag tttcaattac ttattttaca
      781 cctcttcttt agggataaaa cttttcctaa cggtcaattt tgcgccgatt aatgttttct
      841 ttgatatgtc ccgcgaatat accagttgat cacttaataa atctacacag gttttagcta
      901 tctcttcgat atctatctta aaagttgtaa gtggtggtgc aacgaatttt gcgatgtcgt
      961 catcattaat acttattact gccatatctt tagggatgtt aatacccaat tcatggcagc
     1021 cctgaagaac gccggcagct atagtgtcag atggtatgaa acatgcctcg ggcatatctt
     1081 catttaactc agctttcatt ttaagagtta attgataccc ttcgtcaaca gtaaatgatc
     1141 cttgggagaa aatatacttt tcattgagta gtccgctctt ttctaaatga tatcggaagg
     1201 catattcacg gctatcaatc tcttctttac ccgtttctag gttaaagaaa tttcctccaa
     1261 taaatccaat ttttgtgaaa ccttcattaa taaagtagtt aattgcttgt ctggccattt
     1321 cgtggaaatc aggttctaca gtatcgaagt gttcaggtaa tgggtttatt cctcggatta
     1381 cccccttata ccctttttga tttaagtagt acaattcctt ttttgtcaat tgtcctattg
     1441 cgataaatcc agtaatatcg tcaggaatgc tttttacacc atcgttttta gagatgaaaa
     1501 tcaaatctag attagctttt ttactataat ttttcaaatc atctttgaca tgttgatagt
     1561 agacatcctt ttttaactgt tcctctgaga tccaaaaaag aatggcaatc ttgtacagag
     1621 tagtcttaat ttttgtcaga tcatatccta aagatttggc tgtaacgatt attttgtttt
     1681 tagtatcaga tgtaatagag agtgactcat cacctttaaa aagtcttgat atagtagccg
     1741 ttgagtaacc agattttttt gcaatatctc taatagtaac cattgttcat cctcctaggg
     1801 atataataat ccttttcttt gttaaagtaa atcgaaactg ctcttttagt aacttaaatt
     1861 actttttcta gcaggaaacg aaactctgat atcagcagag agcctaatcc attaacagag
     1921 aagattgaat cgataatgga tagccacttg gagaatgatt agtaggtggg attgatttta
     1981 gtgggaatca gtccgttttc ttgtttcgtg taaattaaat tagtaaaaag ataaatttat
     2041 tttacaaaaa aacgtttaca aaacggtttt tgaatggtat atttatttta catcaaggga
     2101 tataagtgct tgtatatcgc aataaaatag atattcgagg tcggtttttc gttgtgtaaa
     2161 aaaatttact tatacatgtt aaaattatgc tgaggtgatt tatggattat tggcatattg
     2221 atcaaactaa ttttcaagga gagattaaaa tgaattataa aactttacca gaagacttta
     2281 ttatgggagg agctacggca gcttatcaag cagaaggctc tacaaaagaa ggtggaaaag
     2341 ggcaagtagc gtgggatact ttccttgtag aaaagggacg ctatactgct gatccagcta
     2401 gtgattttta taatcaatat ccagttgatg ctgaattatg caaaaaattt aaaattgata
     2461 gtattaggat gtctattgca tggagccgta tttttccaaa aggctatggg gaagtgaacc
     2521 aaacaggagt ggaatattat cataaggtat ttgctgaatt gaataagcat ggtattattc
     2581 cttttgtaac tcttcatcat tttgataccc ctaaagaact atttgataat ggagattttt
     2641 taaatcgaga aaatgttgaa catttcgtaa actatgcaca gttctgtttc gatgaatttt
     2701 ctgaggttca ttattggagt acatttaatg agatttatcc agttgcttca aatcaatatt
     2761 tgatcggatc gtttcctcca gaagttcaat ttgatataga gaagactgta acttgtttac
     2821 acaacatgat gtatgcgcac gcaaagacag taaacatttt taaagatggt ggatataaag
     2881 gggaaattgg tgttgttcac tcgctagaga caaaatatcc agcaagtgac aaagaagaag
     2941 ataagcatgc tgcgaaatta gatgatgcgt tatcaattaa gttcttatta gatgctactt
     3001 atttagggta ttactcagat gaaacaatgg cacatattaa tgagatttta gcagcaaatg
     3061 ggcaatctgc agatattgat tctaatgatt ttagagagat gaaaaaagca gcaaatcgaa
     3121 atgattttct tggtatcaat aactatggta gccattgggt taaagagtac aaaggagaaa
     3181 gcacacttca ctacaacact accggagaaa aaggtagcca agtctattgc attaaaggga
     3241 ttggcgagag aatcgtgcgt gaggatcttc cgaaaaccga ttgggattgg atcatttatc
     3301 caaaagggtt atatgattta cttgtacgaa tccaagacga atatccaaat tataataaaa
     3361 tatacattac tgaaaacggg ctagggtata aggataattt tgaagatggg attattctag
     3421 atgatgatcg aatcgattat ttacgccagc attttaatgc gatttccgat gctatcaaaa
     3481 tgggagttaa tgtaaagggg tatttcattt ggtcattaat ggatgttttc tcttgggtta
     3541 atggatacac taagcgttat ggactattct atgtagattt cgatacacaa aaaagatatc
     3601 cgaaagagtc tgcatattgg tataaatttg ttagcgaaac aaaaacgata atataaaaat
     3661 agttaggagg gcaaggaaat ggataggaaa gaattgcaat tattaggatt tgaaattgtt
     3721 gcttatgcag gagatgccag aagttcatta ttaacagtgt tgaaggaagt gagagaaggt
     3781 aattttgata atgttgaacg attattagcg gatgctgatg aaaatttaac cttagcgcat
     3841 aactcacaaa cgaaatgttt agctgaagaa gcgtcaggga acgaaatgga agtaggcgta
     3901 atttttattc atgggcaaga ccatttaatg acaacgattc tattaagaga acttatcaat
     3961 gattttgttg aattgtacaa agaaaaattt gctaaagcat aggagaagaa aaatgaatac
     4021 gattattaag caaattgaga agggaaaacc gttttttgaa aaaatctcac gtaatattta
     4081 tttaggggca attcgcgatg gctttttaac tgctatgcca gctattctat tttcaagtat
     4141 ttttattatg attgcggctg ttccagaagt atttaacgtg acgttaccag aggcattctc
     4201 gacgtggctt tggaaagttt atggttattc aatgggatta gttggtcttt tggttgttgc
     4261 tacaacagct cgatgtttag ctaattcaat gaaccgtcaa ttatctgatt caggtaagca
     4321 gattaatgaa gtttctgtta tgttagcgtc aatttgtggt tttgtaatga tggcagctga
     4381 tcaaattgat ggtgggatag ctactgatta tttagggaca aagggattat tagcagcttt
     4441 cgtttctgcg tttgttactg taaatgtgta taaattctgt gttaaaagag atttgacgat
     4501 ccgtatgcca aaagaagttc ccggaacaat cacacagatg tttagagata ttatcccctt
     4561 ttcaattgca gtatttattg ccgttttgat tgatacggga gttcgtcaat tttttggaac
     4621 atcatttgca gcaggtgtaa ttcaattatt gcagccatta tttagtgctg ctgatggata
     4681 tgtcggtatt gcaatcattt ggggagccat ggcaatgttc tggtttgttg gtgttcatgg
     4741 accatcgatt gttgaaccag cgattgctgc aattatttat gcgaacgtag aaactaactt
     4801 tgaattattt aaaaacggtg cacaagcctc aaaagtatta acagttggtc taggaaactt
     4861 tgttggaacg atgggtggta ctggagcgac actagttgtt ccttttctgt tcatgttgtt
     4921 cgctaaatca aaacaattga aagcagttgg taaagcttca tttattccag tttcgtttgc
     4981 ggtaaatgaa ccgttactat ttgctactcc tattattttg aatccgtact ttctaattcc
     5041 atttttatta gcaccaatcg ctaacgtatg gatattcaaa ctttttgtcg atgtcttggg
     5101 gatgaatagc tttatatccg tattgccttg ggcgacgccc gcaccgattg gcttggtttt
     5161 aggaaccggg tttagtgtgt tggcgattgt attagcggta gtattgattg ttgtcgatgc
     5221 gattatttat ttaccttttg ttaaggccta tgattctgaa ttagtagaac aagagttaaa
     5281 aaacattgct gcagaagaag taaaagaaga attggtcgaa gaaatccaag aagttggtgc
     5341 aactgcggca gttatagttg atgaagcaaa agcatcggtt ggtgaaggaa agcgcgtttt
     5401 agtactttgt gctggtgccg gaacgagtgc aatgttggct aatgcattag aagagggcgc
     5461 aaaagagaca ggtgttaatc tttctgctaa agcaggagct tatggttctc attatgatat
     5521 gatgaaaaat tttgatttaa tcgttctagc acctcaagtg aattcctatt tggatgatct
     5581 ccgtaaagat gcagacaaat tagggataaa agtaattgca actaaaggtg cagaatatat
     5641 caatttaaca cgtgatccta aaggagcagt tgattttgta ttgaagcaat tttagagctt
     5701 gcttagatta ataaagcgct agccaactta gctagcgttt tatcttaaac acaatggtaa
     5761 gcgctatctt tttttgctgt ttaaatttcg ggtattcttt ttgaggcgtc gattgtaaaa
     5821 ttaagctaga caactaaaaa gatcatttgt gctacactca aaatagttcc gaccaaagaa
     5881 ttaataagga gtgagtacaa atgacctaca cccatcttac aacagacgaa ctagtaatca
     5941 tagagtctta tttcaatatc gagaaacctg tcgctcttgt cgcacaaagt ttaaatcgct
     6001 ctagacaaac catttataat gtttattcgt ttctcaaaca aggaaaaaag tgctagatta
     6061 ttaccgtcaa tacaaacaaa ataaatctcg ttgtggacga cgttcaaccg ttttatctga
     6121 tgaacaatca acatatgttc aagaaaaggt agctcaagg
//
LOCUS       DAFTHM010000128         6091 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFTHM010000128 DAFTHM010000000
VERSION     DAFTHM010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.128"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            114..803
                     /locus_tag="L7C88_002537"
     CDS             114..803
                     /locus_tag="L7C88_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559326.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            928..3279
                     /locus_tag="L7C88_002538"
     CDS             928..3279
                     /locus_tag="L7C88_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBP9559327.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3359..3754
                     /locus_tag="L7C88_002539"
     CDS             3359..3754
                     /locus_tag="L7C88_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559328.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4079..4696
                     /locus_tag="L7C88_002540"
     CDS             4079..4696
                     /locus_tag="L7C88_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBP9559329.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            4737..5036
                     /locus_tag="L7C88_002541"
     CDS             4737..5036
                     /locus_tag="L7C88_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBP9559330.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5070..5237
                     /locus_tag="L7C88_002542"
     CDS             5070..5237
                     /locus_tag="L7C88_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBP9559331.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5282..5887)
                     /locus_tag="L7C88_002543"
     CDS             complement(5282..5887)
                     /locus_tag="L7C88_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBP9559332.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2089 a          854 c         1203 g         1945 t
ORIGIN      
        1 ttccaacgct atttcgatta aggatctaaa agagctttta aatagtaaaa gaaatgaatt
       61 aaagcagata aaagaaacta attcagtgga attagagtaa aggaagattc attatgaaaa
      121 agatttttgg tgtttctgtt gggctactta tgatgttaac atttggaaat gcagtatatg
      181 ctgctgagaa agaagttatt tcagatccag agcagtacgc ctcacgatac tttgctgatt
      241 ttgaagaaga agataaagta cttgcattgc cagaaggtgg ttttttaaaa ggggaagcta
      301 aaattgtatc tatggataat ccagatataa ttcaaggttc atataattca gaaactgatc
      361 ctgcttcagt ttcagtgaca gaagcaaaaa aaattgttgc tgaaaaattc aaaaatgata
      421 ttgaaactac tccaattatg cctcgaggag catttccacc cgatgttggt actagcggac
      481 accttcttgt actagcagga ggaggaagct ataaatcaca gccatttagt ggtgcgggat
      541 ggcgttttgg aggtatgggt gtaaaaccag ctgatggtac aggcaacttt ttacgttgga
      601 aatcctacat tgacgatgga agagtaggaa atgtaaatca agccaacgca actaaatctg
      661 gttctattca aggaatggca ttgtatgctc gtgaaggatt caaatacttt gcaccaaacg
      721 ggcctggttg gacaatgaat ataggtattt attacactta taatcctgtt gcaggtacgt
      781 attatgttgt tcaaaatatt taataaaaca gcacaaagag atttctttgt gctgttttat
      841 tatttttagt tgttgacaaa cactaaaata taaaatataa tcaacacata aacgaacgta
      901 tgttcggcaa gaaagcaggg gatttttatg gatgagatgg ttttaagtac tcagaaatgg
      961 ctaaacaaga aatacagtaa tgttacaggg tttgataagg ttccagaaaa tgggcgaaca
     1021 gggtggccta caatctatgg acttattgaa ggactacaag tagaacttgg tattactaat
     1081 ctagtagcta attttggacc taccactgaa aaaatgtacg ataatcaggt tactcctaaa
     1141 tggggcaaaa atctacctaa aaatattgta tttcttattc aaggtgcctt ttggtgtaag
     1201 gggattaatc caggtggctt cgatggggta tatactccat atttagatac tgctgtaaaa
     1261 gagttgcaga ctgatgcagg gtttaatgga agcgctgtaa ctggagtttt ggatgcgaaa
     1321 tgggccaaag cgttatttga tatgagtgct tttgttcttg ttcccggcgg agatagtaaa
     1381 attagaaaaa tgcagcaatg gttaaatgta aattatttag aatacacggg aataatgcct
     1441 tgtgatggta tttatcaaag aaattcaaat caagcattaa tttttgcatt acaagctgaa
     1501 ctaggatatt ctcccagtga agcaacaggg tcttatggta atgggacaac tagtaaaact
     1561 tatcctgtgt ctgaaggtaa ctcgggaaac tatgtaagaa taattcaata tggattatat
     1621 gttaatggtt attttgaaga cggtacattc gatggtattt tcactaaata tatgggttta
     1681 gaagtactgg cattccgaaa atttatggta ttgcctgaat atactgaaat agcagatgtt
     1741 gttgtaataa aaggactatt gtctagcgct ggagatatta gaagatctgc agatggcgca
     1801 gatacttcta cgcaattaac tagatctcaa atccaaacat tggttgataa tgatataaaa
     1861 atagttggta gatatcttac tggtactgtt ggaattggaa aagatgaacg aaataagtat
     1921 ctaactacag aggaattgaa taatattttt tctaaaaatt tatctgtgtt tcctatctat
     1981 caagatggag gtgcagcatt agcttatttt acttatgatc gtggcttatc agatggtaag
     2041 aaggctatag atgcagcaaa aaatctaaat ataccattaa caacagttat ttattttgct
     2101 gttgatctag acatgttagg ggaagaaatt cttgcatatg ctggagaata ttttaagggg
     2161 gtatctgctg taatgtcata tagcgggtat caaacgggtg tttacggaac aagaaatgtt
     2221 tgttctcaaa taatcaataa cgggtatgct tcgtttgcat ttgtttcaga tatgtcgact
     2281 ggttatagtg ggaatttagg ttttcctatg cctagacaat ggtcttttga tcaatttgtt
     2341 gaatttacca taggaagtgg caacggagct gttggtatcg atttaatcgc tacatcgggt
     2401 agagatagcg gatttaatga gttatcaaat gatactaata atgataatta cattgccaaa
     2461 tacaatcaga aggttataaa tcagatggta cgtgcgtatc aatatctatc acaagctggt
     2521 cttgataatc cttggaaccc tcatttgaca ttttatagat atgtaaatta ttctggtttg
     2581 tcatgggaca tcatttcttc tcctgtaaca gagcatgata gaaaaattta tgatgaatat
     2641 aggaataaat taactaatag cgagggcctg tataattatt ttatagatcc taatactggt
     2701 tcaataatag gtttgcctca cttaattgtg acgttacaat cacagatgtt tctagccgac
     2761 acaatcaatg atagtgtttc tgactttgca ggttggttag gagatttaat gacttgctgg
     2821 ggtgaagtta agaaattagg aatacaaatg gagcaaggtg tatttgcatt agtaggtacg
     2881 gctgcaggtg gaacatttag tctagaagat ttataccaag atgttgacgc ggtaaatgtt
     2941 tataccttag caaaaagaaa ttctgattca acagctttat cggctttaaa aacgtactat
     3001 tgtgataagg gtgctattga tagatttaat caatttgtta agaacagatt tggttcttca
     3061 gataaaatcg cttcagtaac aaatagttta ttagaaaatg acgaaacagt tgatatctta
     3121 ggtgtaggga taatttcatt tttcattgat aaaatagtta ataattcact tgggacagat
     3181 tttacttatc ttgattttat tggagatgag gggaaagttg caaatggatt ttctgaaaaa
     3241 attattcaat ttcaagaaaa tagaagtaaa cttaattaag aatcgtttac tatttaaaca
     3301 gtgtcctttt cctttttaaa tatatacgat aaaataagta tatgaattgt aaaaggacat
     3361 gatgattatg gaagaaatag aatggaataa tctgactcaa aataataaaa ataattctgg
     3421 atgtggaatt atctttatgt ttgttatagt tttgggaata gtagtacttt taataactgt
     3481 caagatagta gattactttg cgaatactcc tgaagaacaa atacagagaa aacttcctga
     3541 gtttgaaaga gtaccacctt atgatccaag agataattca tttcaagtaa aaaaattaaa
     3601 agagtctcca aatgaaatgt ggtttgaagt tacagttgaa tcaagcgact tcaaagaaaa
     3661 aaagaaagaa tacaattata ttgtaaaggc aaaagtatca aaaagattta tttttaaccc
     3721 taaattagaa atatatagtg ttgtaataga ataatagtgt taaaaaaatt gtaaaagtta
     3781 aagaagtcaa attctgatgt gaaaaataaa atataccatg gaagacataa aagaaaaact
     3841 ggataactag tttatttaat ggcagaccgt taaggcctgc catttttatg tattttagcg
     3901 gaataaatat aatcatgcgg gagtgtaaac ttactgtttc aaaaagtata ctttttgaca
     3961 tgccttgatt ttctttgttt atgtatggca taataaccac ataatacaat ttgaaacgtt
     4021 tctgatttaa tctgattgtt ttgaaacaat tttagtgaaa aaagggtaga taaaaacgat
     4081 gagaaaattt ttttatatcc gggtcagtag ttatgatcaa tcgatcgaac gacaactgat
     4141 ttccgcgaag gaattaggaa tccctgaaga atatatattt gtagaaaaag ccagcggcaa
     4201 agattttaaa cgccctgaat atcaattaat gaaacggatg tttcgaaaag gagatttact
     4261 ctatctacaa tcattagata gactaggcag aaataaacaa atgattttag aagaatggcg
     4321 agaattaact aaggaaaagc agattgatat ttctgtgtta gacatgcctc tgttagatac
     4381 tgctagttac aagcaactag atgggttaga gacgcttatc tctgacttaa ttctgcaatt
     4441 actcagctat atggccgaag acgagcggaa acgaattaat agccggcaaa gagaaggcgt
     4501 agaagctgcg aaacaaaagg gtgtaaaatt cggcagaaag aaaattgctt tacctcctga
     4561 atttcctgcg atctattctg actggaaagc aggaaagata actgcagtct atgctatgga
     4621 tcaattgggc atgaaacgaa atacctttta tcgacgggtg aaagaatatg aacatacctt
     4681 gcaccacttt tcttgataga tataacagct attagacggg aagggagagt ttgaaaatgg
     4741 acttaacgaa tcaaagggtc gtttttactg gaacgctgca gcaaatgaca cgaacccaag
     4801 ccatcggttt ggttcactct ttaaacggcc attgtcaatc aagtgttact tcaaaaacaa
     4861 atttcctggt ttgtggtcag tattctaagt cgttgtttga tgattctctc tatacaaaaa
     4921 aggaacaaac cgcgcgggac ttgattgcgt taggtcatga gattaccatt ttatcagaag
     4981 tcgaatttta tgcgttaatt agtcaacagt tgaaagaatg gcaacggtat ttataatcgt
     5041 tagtaaaatt tacaaggagg aaaattttta tgaagcgaaa atcttatgat cgttggggca
     5101 ttgaaataac tagttttaat cgaaatattg cttttcacgt ggagtgtgac tgtggggaat
     5161 tagcaaaaag tgtttatcaa aaaaattact tttactgtcc taaatgccat cgccgatacg
     5221 gggtacatgg aacatagaaa cgaaatagtg cggtagaaaa gcgaatgaat gtagtatatt
     5281 tctacaaatc attcgctttc tttattttat aaatagttgg tcgagagatc ccgttttctt
     5341 ttgcaatctc tgcaactgga atgccttgct ttaacatgtc caccacggtt ttaaaaacta
     5401 agcgtttttg cggatctgtt gagttaatag aatactcgat tggtcgtccc ttatatcggc
     5461 cggctttttg agccaataat actccttgcc gctgacgttc acgaattttc tcacgctcgt
     5521 tttgtgcaat ataacttagc agtgataaaa acatatcgaa catagcggta tccaggagtt
     5581 catttccagt attaaaatct aaaaactgtg catctaatat ttttaacgct acttttttct
     5641 gtttcataaa agcaactgta ttttttatat cttcataatc tcttcctaaa cgatctagtg
     5701 atgtaacgat gacgcaatca ccttcacgga tataatttag taatttttga aactcaggac
     5761 gctcagtatc tttaccactg gctttttctt ggaataattt atcaatgtta agtccttcca
     5821 tcattgccaa ttgtcgatcc aaattttgat cttgtgaaga tactcgaata tagccaattt
     5881 ttcccataaa aaactccttt ttaaaagtga tataatttac atgtaaaatt tacttgtagt
     5941 tttactgcta tcatagcatt tttaaaaata aattttatgt agacttaaaa tttacttcat
     6001 ggagggttta aatggatgaa atcaaaagta acaaaaaagc atttggcatt tatttaggag
     6061 aacctagtac agaacaatta aaccaatttt t
//
LOCUS       DAFTHM010000129         6036 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFTHM010000129 DAFTHM010000000
VERSION     DAFTHM010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.129"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(248..733)
                     /locus_tag="L7C88_002544"
     CDS             complement(248..733)
                     /locus_tag="L7C88_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559333.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(872..1087)
                     /locus_tag="L7C88_002545"
     CDS             complement(872..1087)
                     /locus_tag="L7C88_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBP9559334.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            1311..2111
                     /locus_tag="L7C88_002546"
     CDS             1311..2111
                     /locus_tag="L7C88_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBP9559335.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIKEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            2130..3998
                     /locus_tag="L7C88_002547"
     CDS             2130..3998
                     /locus_tag="L7C88_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBP9559336.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     ANLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            3991..4482
                     /locus_tag="L7C88_002548"
     CDS             3991..4482
                     /locus_tag="L7C88_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBP9559337.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            4470..5024
                     /gene="srlA"
                     /locus_tag="L7C88_002549"
     CDS             4470..5024
                     /gene="srlA"
                     /locus_tag="L7C88_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBP9559338.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            5042..>6036
                     /locus_tag="L7C88_002550"
     CDS             5042..>6036
                     /locus_tag="L7C88_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBP9559339.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2122 a          962 c         1214 g         1738 t
ORIGIN      
        1 tatagaaaaa ttgaatctag aaaaccgccc gacaataaat ttcattaact cagttgaccg
       61 aaaatgaagt agataccaaa aatttatcaa gagagcaagt agagaagtga gtatattcat
      121 aagagaaata gctgtaacga attattaggt taatgcaaat gcttatttat actccgtata
      181 actttctcag aaaaaatgat accaataatg acttgctagt actgtaaatc cgtataatat
      241 catctaatca aaatggtgtt ccatttgcat ctgtcatcgt aatcgatcct tcgggtgaca
      301 ctcgataaaa accaacgctt ccagatcctc cttgggaacg gatttgtttg ctggaagctg
      361 tgaacaaata atctcgatca attttttgat aaaagctaat aacaatatcg tcactttgta
      421 attcggaacg gtgggcaata agaaatagaa gtgctttgtc agagttttct aatggaagag
      481 aaggtacagt gctttcttgc atttcagatg ttgaagaaat gctaaacgac tgaatacttg
      541 attggctatg ttgcgaatct acattaccag tagaagtatt agtaatggaa gtagtagaag
      601 tacttttagt tgaaccaacc tcagttgttg aaatggctgc tgaagattct ttaacagaat
      661 tctttgtttt atatccacag gcagaaaaaa gtattacagt tcccaacaag cctgcgtaaa
      721 tccctttatg catgatagct cctcctaaaa tagattatct ttattcagta tatcacttaa
      781 acaaagaaaa gcagatggtt taaaatgaaa aaaccttccc aataaaggga aggttcatga
      841 agataataac ttttttaata attatagctt tctaatatct ttcatcaact tttctagtaa
      901 tcattgggaa aaatttcaag cagtagatcg cacaaatacc tacgacgata taaatgatct
      961 tcgcaaaaat agttgttgaa ccaccagcaa tcatagctac taaatcaagt tcgaacaagc
     1021 ctaccaacag ccagttcaac cctcccacaa tcaataaagt taatgcaata gcatctaaag
     1081 ttttcattag aattctcctt tcttaaatga taaaacaatt atatatcaaa aagagaaaca
     1141 ttgcttatat aacgctcagg aattttagca atctatgcaa aaagatgaaa attttttttg
     1201 ctcttccatt agtacacatt ttttagctga agctgtaaat ttcatgtctt aatttttttt
     1261 agtgagcttt tatactggat ttgtaagaaa aaagaaggag aggatcacat atgtcggatt
     1321 ggttggatat tgcaggaaaa gtagtaattg taactggagg ttcctcagga attggaagaa
     1381 gtatcgtcga aaatttgttg aagcagaatg cacaagtagc gaattttgat gtaactgaat
     1441 gccgtataca gcatgaaaac ctactatctt taaaagtcga tgtgtcttct aaaacggaca
     1501 taaaagaagg gatatataaa gtaatgaaac attttaagac gatcgatggt ctagtcaata
     1561 atgcaggaat aaatattcct tctcttctaa tagatagaaa tcatccaaaa agcaagtatg
     1621 aattatcaga acaagttttt gataagatga tcgctgtcaa tcaaaaaagt gtatatttga
     1681 tgagccaagc agttggaaga atcttggtgc aaaagggatc aggagtgatc gtgaatcttt
     1741 cttctgaatc aggattggaa ggatcagaag gacagagctg ttatgctgct acaaaagcag
     1801 cgatgaacag ttttactcgt tcttgggcaa aagagttagg aaagaggaat gttcgtgtgg
     1861 taggtgttgc accagggata ctggaagaaa ccggtttgag aacacaagaa tatgaagaag
     1921 ctctttctta tacgagaggt ataagcgtcg aacagctgag aaacggttac agtcgaacaa
     1981 gtacgatccc tctaggaagg agtggtaagc tgcaagaagt ggcggatcta gtctgctatt
     2041 atctttcaga aagatcaagt tatatcactg gagtcacgac taatatttca ggaggtaaaa
     2101 caagaggata aaggataggg gggacgcacg tgacgctagt aaacagatgg taccaattat
     2161 tgaaattact agtcactcac aagaaagttt caatccagga agtgcaaaaa gaaatcaaaa
     2221 ccagtaatca aaccataaaa aaagatattg gggagttgaa tgaagaaatt gccggtattg
     2281 caaaaatcat ccaaaaaaac aaacattttg aacttgaaat ttatgatttt gatttttttg
     2341 atgagatcat gcaaggaaaa ttgaaaacag ccagtgattt caattcggca tccaaaagaa
     2401 tcgcttattt actaaatagg ctgatcgaaa cagaggattt cttacgtatg gatgatttgt
     2461 ctgaagaagt cggtgtcagc agaggaacag tggtcaagga tctaaagaca ttaaaagaga
     2521 tgatcaatga ttttgatgta aagattacag gcacaccaaa taaaggacta agaataatag
     2581 gagatgagct agaattacga ctacttttat tttattttgt ttctccctac ttttcagaga
     2641 cgaaaacaga acagtttcta gaagaaaaac aagcaatcaa acattttcag aagaagacga
     2701 atgctagtaa acaagaaatc acccttttaa cgaaagttat cggtatttct ttgaatagaa
     2761 tctctagtaa ctatctgttg aagaagccca tcaatcgtta cagtgggtgt tttgaatata
     2821 tccaagaatt caatgaactg atcaatcagt tggaagaaat ctatgaacta actttgagcc
     2881 aatatgaaaa agattttatc agttttcctt tgaacatcat caacacaagt ataacgatga
     2941 taaggaaagc taactctgat ttgcgcttat atttcgaccc catgatgatg cgtattcgac
     3001 gattagatct cattgatctg gatgagtcct tcttatatca agagatgaaa cagcacctct
     3061 ctttattgat aaatcgggta atttttcgtt atcgattgac tgatttattt tatggtgaga
     3121 tagaaaaaaa gtatcctttt tcttaccaaa tcgctagcga atgcatacaa gcattagaag
     3181 ctatcttgca acataagatc tctaaagtag agatcagcta cctaacgttg tatttggagt
     3241 tagcatttcg atatcaaaaa gagcattttt cctctaaaaa agtagccatt gttcatacga
     3301 caggaaaagg aacagcatta atgatccaaa gacaaatcaa aaggatattg gggagggata
     3361 tacaaataac acatgtttca gaagaacaat atgaaaaagt agatctaaac aaatatttcg
     3421 ctgtttttac aacgattccg ttaaaaaatg taaatgaaga gacaccggtg atccatttgg
     3481 ctaatctttt tgatgactct tggttaaggg cacaatggca aaaagcaaaa aaaaagcgat
     3541 tagccgggtt tcattctact gtttttttct atcaaatatg gaaagaaaaa aagacgtatc
     3601 aagaatattt aaacaaatta gtcgctcctt tgatcagagg ctattatgtg gatgaagaat
     3661 ttgaaaaaag gatcttgaaa agagaatatc agcaaagcac atttgttaac aaagaatttg
     3721 cttttcctca cacaaccaac cagctatctc aacacattgt tttatcagta gggctaataa
     3781 ctgatcaagg tttagcagaa acaggaggaa atggagttat ttttttattt gccatacctg
     3841 aagaaatgac ggctgaagtt gagaatgaat tatttgagct atacgatatc ctatttgaac
     3901 tcataaaaat gggaatagat gagtttattg aattagcacc gacacaagaa tcatttttaa
     3961 aactaatcaa aagtaaagga gagagacttc atgaatgata tgtatctatt catagttttc
     4021 gcagcttcag cttatgtgct gcaagcagtt atcagttgga agcaactaaa gcatttcaat
     4081 caaacatata gcgaactgcg aagaaaagga aaagtagcga ttggtaaacg acctgggaaa
     4141 atccgttcag gcacgattgt tatgctagct atagacgatc atgatcaagt tttagaagtc
     4201 agaaaaatgc aaggggttac atctttggca aaatttcatt cattacctgt ctatgcgggt
     4261 gaagatatcc attacatcga tcgttaccat ccctcagttc gagcggaaga tcgtttgaca
     4321 caagcagctt tagaaaatgc cagagaagta tacttacgaa tagaggcagg aaatgaaaaa
     4381 agtgaacaac cttcattgcc ttttattgct atgctcaata attttcggat atggaaaagt
     4441 acgatcaaag aaaaaaggag tgacaaacga tggatatcat aacaaaattt gctgagggat
     4501 ttatgaggct gttccaaaca ggtgcagaaa cattcataag ctggatgaca ggaatcgtac
     4561 cagttgtctt gatgctgatg gttgcaatga atacgctgat tgctttttta ggtgaagacc
     4621 gagtaacgaa agtagccaaa ttatcagcga aaaatccgct tactcgttac cttgtgttac
     4681 cgttcttatc tgcttttatg ttgggaaatc ctatgtcatt tacaatggct cgtttccttc
     4741 cagaatacta caaaccaagc tattatgctg ctcaagctca attttgtcat acgagcaatg
     4801 gtgtattccc ccatattaat cctggagaat tgtttgtatg gatggggatt gctcaaggga
     4861 tcgaaacctt agggctaaat tcgatggagc tggctatccg atacttgctt gtgggactgc
     4921 tgatgaactt tattggtggt tggataactg attttactac tggatttgta tgcagacagc
     4981 aaggaatcgt tcttagcaaa aaagtagagc tttcagttga ttagagaaag gagagtttta
     5041 aatgtatggt gatattaaga tcgtaagagg aaacggcggg tatggaggtc ctttgattat
     5101 taggccgaca aaagataaac acaagttcat ctatgtcaca ggtggaggtg agaggccaat
     5161 gatcgtagat aaaatagaag aactgacagg tatggagtct atcaatgggt tcaaaacatc
     5221 aatacctgat agtgaaatcg cgcttgcaat cgttgactgt ggagggactc ttagatgtgg
     5281 aatttatcct aaaaaaggga taccaaccat caatatcgtt cccacaggaa aaagtggccc
     5341 attagcacaa tatatcactg aagatattta tgtttcagca gtagggttag aacaaataca
     5401 gccactaatg gaaactgatg ataacaaaga aacagtaaat actgcatctc cagataaaaa
     5461 gtacaaatat gatacttcta aaaagataac cgagcaaaaa gcagagcagc aaaactggat
     5521 agcaaaaatt ggaatgggcg cgggaaaagt agttgctaca ttcaatcaat cagcaagaga
     5581 agcagtagat acgatgatcc ggacagtgat cccttttatg gctttcgttt cccttttgat
     5641 tggtgtgata caaggttctg ggatcggtaa tgtatttgct aacattatgg cacctttagc
     5701 aggaaatgca gttggattaa caatcattgg ctttatttgt tcactgccat ttttatctcc
     5761 tttgcttggt ccaggggcag ttattagcca agtgattgga acattgatcg gtgtagagat
     5821 tgggaaagga aatattcctc cccaattagc attaccggca ctatttgcta tcaatactca
     5881 aaatgcatgt gattttattc cagtcggtct aggtttggaa gaagcaaaag ctgagacagt
     5941 agaagtaggt gtaccatcag ttctttattc aagatttctt aacggcatcc cacgagttat
     6001 cattgcttgg gtagcaagtt ttggattata tagctg
//
LOCUS       DAFTHM010000130         5984 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFTHM010000130 DAFTHM010000000
VERSION     DAFTHM010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5984
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.131"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            352..1041
                     /locus_tag="L7C88_002551"
     CDS             352..1041
                     /locus_tag="L7C88_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9559340.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="L7C88_002552"
     CDS             1028..2236
                     /locus_tag="L7C88_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBP9559341.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="L7C88_002553"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="L7C88_002553"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBP9559342.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="L7C88_002554"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="L7C88_002554"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBP9559343.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
BASE COUNT         1836 a         1129 c         1160 g         1859 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgtggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtatattaaa agagattgta aaaa
//
LOCUS       DAFTHM010000131         5903 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFTHM010000131 DAFTHM010000000
VERSION     DAFTHM010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.132"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..985)
                     /locus_tag="L7C88_002555"
     CDS             complement(<1..985)
                     /locus_tag="L7C88_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HBP9559344.1"
                     /translation="MTQVHFTLNNEEVQSIIEHSVKDDVSKNILTTVFNQLMENQRTE
                     YIQADDYERSESRQSQRNGYYERDFTTRVGTLELKVPRTRDGEFSPTVFERYQRNEKA
                     LLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLDPMVNEWQNRSLSGTN
                     YPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDREIIGFMIQNEESDDTWSIFFEY
                     LKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFSSIPKKNSKPFRE
                     AVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACEILDNGFEDAFQYTVIG"
     gene            1137..1832
                     /gene="vanR"
                     /locus_tag="L7C88_002556"
     CDS             1137..1832
                     /gene="vanR"
                     /locus_tag="L7C88_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBP9559345.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1810..2964
                     /locus_tag="L7C88_002557"
     CDS             1810..2964
                     /locus_tag="L7C88_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBP9559346.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            3179..4147
                     /locus_tag="L7C88_002558"
     CDS             3179..4147
                     /locus_tag="L7C88_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBP9559347.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            4140..5171
                     /gene="vanA"
                     /locus_tag="L7C88_002559"
     CDS             4140..5171
                     /gene="vanA"
                     /locus_tag="L7C88_002559"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBP9559348.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            5177..5785
                     /locus_tag="L7C88_002560"
     CDS             5177..5785
                     /locus_tag="L7C88_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBP9559349.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1782 a         1149 c         1335 g         1637 t
ORIGIN      
        1 ttccgataac cgtgtattga aaggcatctt cgaagccatt atccaatatt tcgcaggctt
       61 ttgtatattt aggctggtcg atatattcac cgactaaggc attcttagct gttcgagcga
      121 gttcaatatc cgtaaactta aagatcgctt ttactgcttc tctaaacggt tttgaattct
      181 tttttggaat ggaactgaag atgtttctta aaaaatggac ctggcatctc tgccaacttg
      241 cgttggtaaa tgacttacga atcgcagaca ctaggccttt atgggcatca gaaatgatga
      301 gttctgtccc ctttaggccg cgttctttta agtattcaaa gaagatggac catgtgtcat
      361 cactttcttc attttgaatc atgaagccaa tgatttcacg gtcgccacct tctgttatcc
      421 cgatcgcaat atggcagctt ttagaaagca ctcgatggtc ctcacggact tttatgtaga
      481 gaacatcagt catcagataa ggataattcg tacctgagag tgaacggttc tgccattcgt
      541 tgaccatcgg gtctaactgc tcagtcaggc tagaaacaaa agatttcgat acagattttc
      601 cacatagctc ttcaacaatc tttgaaactt tacgtgtcga aacgcccgaa acatacatct
      661 caagcattga agcgagcagt gccttttcat ttcgctgata acgctcaaac accgtcggtg
      721 aaaattcacc atcacgtgtt ctaggcactt ttaattcgag tgtacccaca cgagtcgtaa
      781 agtctcgctc ataatagcca tttctttgac tctgacgact ttctgaacgt tcatagtcat
      841 cggcttgaat atattctgtt cgttgatttt ccatcaattg gttgaaaaca gtggttaaaa
      901 tatttttaga aacatcatct tttaccgaat gttcaataat actttgaacc tcttcgttgt
      961 tcagtgtaaa atgtacttgg gtcatgtaac gtcctcctgg gtatgttttt gtggttaaaa
     1021 acattgtacc gtaaaagggc tgttacatgg ccttttatct tttacacaat tatatggact
     1081 ttatcctata atctgataaa ttattaaggg caaacttatg tgaaagggtg ataactatga
     1141 gcgataaaat acttattgtg gatgatgaac atgaaattgc cgatttggtt gaattatact
     1201 taaaaaacga gaattatacg gttttcaaat actataccgc caaagaagca ttggaatgta
     1261 tagacaagtc tgagattgac cttgccatat tggacatcat gcttcccggc acaagcggcc
     1321 ttactatctg tcaaaaaata agggacaagc acacctatcc gattatcatg ctgaccggga
     1381 aagatacaga ggtagataaa attacagggt taacaatcgg cgcggatgat tatataacga
     1441 agccctttcg cccactggag ttaattgctc gggtaaaggc ccagttgcgc cgatacaaaa
     1501 aattcagtgg agtaaaggag cagaacgaaa atgttatcgt ccactccggc cttgtcatta
     1561 atgttaacac ccatgagtgt tatctgaacg agaagcagtt atcccttact cccaccgagt
     1621 tttcaatact gcgaatcctc tgtgaaaaca aggggaatgt ggttagctcc gagctgctat
     1681 ttcatgagat atggggcgac gaatatttca gcaagagcaa caacaccatc accgtgcata
     1741 tccggcattt gcgcgaaaaa atgaacgaca ccattgataa tccgaaatat ataaaaacgg
     1801 tatggggggt tggttataaa attgaaaaat aaaaaaaacg actattccaa actagaacga
     1861 aaactttaca tgtatatcgt tgcaattgtt gtggtagcaa ttgtattcgt gttgtatatt
     1921 cgttcaatga tccgagggaa acttggggat tggatcttaa gtattttgga aaacaaatat
     1981 gacttaaatc acctggacgc gatgaaatta tatcaatatt ccatacggaa caatatagat
     2041 atctttattt atgtggcgat tgtcattagt attcttattc tatgtcgcgt catgctttca
     2101 aaattcgcaa aatactttga cgagataaat accggcattg atgtacttat tcagaacgaa
     2161 gataaacaaa ttgagctttc tgcggaaatg gatgttatgg aacaaaagct caacacatta
     2221 aaacggactc tggaaaagcg agagcaggat gcaaagctgg ccgaacaaag aaaaaatgac
     2281 gttgttatgt acttggcgca cgatattaaa acgcccctta catccattat cggttatttg
     2341 agcctgcttg acgaggctcc agacatgccg gtagatcaaa aggcaaagta tgtgcatatc
     2401 acgttggaca aagcgtatcg actcgaacag ctaatcgacg agttttttga gattacacgg
     2461 tataacctac aaacgataac gctaacaaaa acgcacatag acctatacta tatgctggtg
     2521 cagatgaccg atgaatttta tcctcagctt tccgcacatg gaaaacaggc ggttattcac
     2581 gcccccgagg atctgaccgt gtccggcgac cctgataaac tcgcgagagt ctttaacaac
     2641 attttgaaaa acgccgctgc atacagtgag gataacagca tcattgacat taccgcgggc
     2701 ctctccgggg atgtggtgtc aatcgaattc aagaacactg gaagcatccc aaaagataag
     2761 ctagctgcca tatttgaaaa gttctatagg ctggacaatg ctcgttcttc cgatacgggt
     2821 ggcgcgggac ttggattggc gattgcaaaa gaaattattg ttcagcatgg agggcagatt
     2881 tacgcggaaa gcaatgataa ctatacgacg tttagggtag agcttccagc gatgccagac
     2941 ttggttgata aaaggaggtc ctaagagatg tatataattt tttaggaaaa tctcaaggtt
     3001 atctttactt tttcttagga aattaacaat ttaatattaa gaaacggctc gttcttacac
     3061 ggtagactta ataccgtaag aacgagccgt tttcgttctt cagagaaaga tttgacaaga
     3121 ttaccattgg catccccgtt ttatttggtg cctttcacag aaagggttgg tcttaattat
     3181 gaataacatc ggcattactg tttatggatg tgagcaggat gaggcagatg cattccatgc
     3241 tctttcgcct cgctttggcg ttatggcaac gataattaac gccaacgtgt cggaatccaa
     3301 cgccaaatcc gcgcctttca atcaatgtat cagtgtggga cataaatcag agatttccgc
     3361 ctctattctt cttgcgctga agagagccgg tgtgaaatat atttctaccc gaagcatcgg
     3421 ctgcaatcat atagatacaa ctgctgctaa gagaatgggc atcactgtcg acaatgtggc
     3481 gtactcgccg gatagcgttg ccgattatac tatgatgcta attcttatgg cagtacgcaa
     3541 cgtaaaatcg attgtgcgct ctgtggaaaa acatgatttc aggttggaca gcgaccgtgg
     3601 caaggtactc agcgacatga cagttggtgt ggtgggaacg ggccagatag gcaaagcggt
     3661 tattgagcgg ctgcgaggat ttggatgtaa agtgttggct tatagtcgca gccgaagtat
     3721 agaggtaaac tatgtaccgt ttgatgagtt gctgcaaaat agcgatatcg ttacgcttca
     3781 tgtgccgctc aatacggata cgcactatat tatcagccac gaacaaatac agagaatgaa
     3841 gcaaggagca tttcttatca atactgggcg cggtccactt gtagatacct atgagttggt
     3901 taaagcatta gaaaacggga aactgggcgg tgccgcattg gatgtattgg aaggagagga
     3961 agagtttttc tactctgatt gcacccaaaa accaattgat aatcaatttt tacttaaact
     4021 tcaaagaatg cctaacgtga taatcacacc gcatacggcc tattataccg agcaagcgtt
     4081 gcgtgatacc gttgaaaaaa ccattaaaaa ctgtttggat tttgaaagga gacaggagca
     4141 tgaatagaat aaaagttgca atactgtttg ggggttgctc agaggagcat gacgtatcgg
     4201 taaaatctgc aatagagata gccgctaaca ttaataaaga aaaatacgag ccgttataca
     4261 ttggaattac gaaatctggt gtatggaaaa tgtgcgaaaa accttgcgcg gaatgggaaa
     4321 acgacaattg ctattcagct gtactctcgc cggataaaaa aatgcacgga ttacttgtta
     4381 aaaagaacca tgaatatgaa atcaaccatg ttgatgtagc attttcagct ttgcatggca
     4441 agtcaggtga agatggatcc atacaaggtc tgtttgaatt gtccggtatc ccttttgtag
     4501 gctgcgatat tcaaagctca gcaatttgta tggacaaatc gttgacatac atcgttgcga
     4561 aaaatgctgg gatagctact cccgcctttt gggttattaa taaagatgat aggccggtgg
     4621 cagctacgtt tacctatcct gtttttgtta agccggcgcg ttcaggctca tccttcggtg
     4681 tgaaaaaagt caatagcgcg gacgaattgg actacgcaat tgaatcggca agacaatatg
     4741 acagcaaaat cttaattgag caggctgttt cgggctgtga ggtcggttgt gcggtattgg
     4801 gaaacagtgc cgcgttagtt gttggcgagg tggaccaaat caggctgcag tacggaatct
     4861 ttcgtattca tcaggaagtc gagccggaaa aaggctctga aaacgcagtt ataaccgttc
     4921 ccgcagacct ttcagcagag gagcgaggac ggatacagga aacggcaaaa aaaatatata
     4981 aagcgctcgg ctgtagaggt ctagcccgtg tggatatgtt tttacaagat aacggccgca
     5041 ttgtactgaa cgaagtcaat actctgcccg gtttcacgtc atacagtcgt tatccccgta
     5101 tgatggccgc tgcaggtatt gcacttcccg aactgattga ccgcttgatc gtattagcgt
     5161 taaaggggtg ataagcatgg aaataggatt tactttttta gatgaaatag tacacggtgt
     5221 tcgttgggac gctaaatatg ccacttggga taatttcacc ggaaaaccgg ttgacggtta
     5281 tgaagtaaat cgcattgtag ggacatacga gttggctgaa tcgcttttga aggcaaaaga
     5341 actggctgct acccaagggt acggattgct tctatgggac ggttaccgtc ctaagcgtgc
     5401 tgtaaactgt tttatgcaat gggctgcaca gccggaaaat aacctgacaa aggaaagtta
     5461 ttatcccaat attgaccgaa ctgagatgat ttcaaaagga tacgtggctt caaaatcaag
     5521 ccatagccgc ggcagtgcca ttgatcttac gctttatcga ttagacacgg gtgagcttgt
     5581 accaatgggg agccgatttg attttatgga tgaacgctct catcatgcgg caaatggaat
     5641 atcatgcaat gaagcgcaaa atcgcagacg tttgcgctcc atcatggaaa acagtgggtt
     5701 tgaagcatat agcctcgaat ggtggcacta tgtattaaga gacgaaccat accccaatag
     5761 ctattttgat ttccccgtta aataaacttt taaccgttgc acggacaaac tatataagct
     5821 aactctttcg gcaggaaacc cgacgtatgt aactggttct tagggaattt atatatagta
     5881 gatagtattg aagatgtaag gca
//
LOCUS       DAFTHM010000132         5809 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFTHM010000132 DAFTHM010000000
VERSION     DAFTHM010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.133"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            450..1604
                     /locus_tag="L7C88_002561"
     CDS             450..1604
                     /locus_tag="L7C88_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBP9559350.1"
                     /translation="MIILKPKNKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYVYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1598..2020
                     /locus_tag="L7C88_002562"
     CDS             1598..2020
                     /locus_tag="L7C88_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559351.1"
                     /translation="MVNKPIVLVMGLVLVLFLTSCSKKQEIQKTELIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            3143..4075
                     /locus_tag="L7C88_002563"
     CDS             3143..4075
                     /locus_tag="L7C88_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBP9559352.1"
                     /translation="MANEIVKYKPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFDQLKDLSAYKQTAGEVFIKDLTRTYDHLMDLRFGKKSNGGLTIERFTMFTDFEIH
                     GEADNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRTKLFNIEHNGELTQEEKWRAKDRILDLPLGTHEAN
                     FKKQQQTEKEEVEKQTLSNELKQDLLGNLQNLFD"
     gene            4092..4607
                     /locus_tag="L7C88_002564"
     CDS             4092..4607
                     /locus_tag="L7C88_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBP9559353.1"
                     /translation="MADKTIKDLAEELGVSKTAINKKVSDENRKLWFAKIGNKFVINE
                     IGQKAIKSMFFTENENSNQQPVGEKSKTENHKNANQVSELELFFFLEKQLNQKDIQLQ
                     EKDEQLKQMQKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQ
                     NKEKKWWQFWQ"
     gene            4903..5184
                     /locus_tag="L7C88_002565"
     CDS             4903..5184
                     /locus_tag="L7C88_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559354.1"
                     /translation="MDILVRNINPKIITRVDKRCQELTTKTGEKWSRNKYLKVLIESD
                     FDRQLMNYKKEQFDLLLEKFIDIQTKNTETLNDYVHTNNQLIETLIGGI"
     gene            5186..5602
                     /locus_tag="L7C88_002566"
     CDS             5186..5602
                     /locus_tag="L7C88_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559355.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EKQLNPSQRNQPKNRQKETSQTFTSKNFDPTNFLKR"
BASE COUNT         2228 a          961 c          930 g         1690 t
ORIGIN      
        1 aaaaaaaaag actgctcgaa agagcagtct caagcaaaaa ataaacgaac aaacgcaatt
       61 actcacgaac acaaacaaat acaataaaat acctaaataa tgaaaataag tgataaaaaa
      121 caagggtatt tatagtttaa caagcgctca taaaaataac aagtctttaa aaaatgacag
      181 ataaaaatgc acaaagaatc ggacacagat aaccgcgaaa aatcaagctt tagaaagttg
      241 tttttagcta gaccaatgaa aaatcacaaa gtccgcccct gtatccgttg gtagaggggc
      301 tacttggttt agtatacatt atgttaacta gctcgttaaa taacgattat gttcccaaaa
      361 caatatttta tgaactataa caaaaatttg ttatcgcata ttgtatattt taattatagg
      421 tgtatatcac ttaattttaa cacaaaggcg tgattatttt gaaacccaaa aataaaattt
      481 atctaggtct cctcttttcc ttgatgattg gaatttttag tataggaatt acaaatacct
      541 atgcttcaga aaattctaat ttcaatatca actcccaacc aattgaagaa caagcaatta
      601 attttgcgaa aactgatttt gaacactcca taacttcaat tcttttaatg gaaaataaca
      661 ctgaaactga tattaactat actcttggtt cgccatttaa aatgctcgat ggagaaaata
      721 cggcaaatag ttctattttc tttccagtat tttcagacgc tgataatacg attaaatatg
      781 tttataccgt caaaaaaaat acaaatggag aatattcagg aagtatttca caatttttag
      841 caaaagaact tcaaaatcta gtagatagca atataacaga tacaacctta ttttttcaag
      901 ataatagcat ttattattcc gataatggcc aaattaaact actttggaaa tcacctttaa
      961 gtacagaaaa aaatggtgtc tcttccttta cagaaaaaaa tgatcttata tccgtaaata
     1021 taaaaaataa aattaaaaat ttctctaaaa aacaaaattt tcctgcggtt aaacgtgtaa
     1081 aaagtgtctc ctccggagat aactttatta tgattaattg gcgtatagca gaaacccaaa
     1141 caagttttcc gtggtgcgct gcttacgtag aagctgctat cttatgtaat aaaacagatg
     1201 tacgcgctac ttcagctaga gccattatgc attataccta tcctaattta aacaacagtc
     1261 aaattgaatc aaaaagtctt aatcaagatc aaataataaa atatgcaaat tactgtggtg
     1321 tttatcctaa aaaagtagca cgaatactaa acctttcaga ggtccaaaca caactaagaa
     1381 aaggaaatgc catttatatg ggaactgctg gttatggaaa ttatagtaac agccgtcatg
     1441 cacttgcatt atttgggtgg gtcaatcaag gtggttatca aacttactat gtgtggaatc
     1501 cttggtataa ctacccaact gtaataagtg caaatgcagg gccagttaca attcctgtac
     1561 ctggaggtgg ttttacttgg gacaatacca ttacaaattg gtaaataaac ccattgtttt
     1621 agttatgggt ctagtgttag ttcttttctt aactagttgt tcaaaaaaac aagaaataca
     1681 aaagactgag ctgattcctt ttctaggaac ttggcaaact aaagatcact cagaacgtct
     1741 agtaatcact aatttaaata cttcaaaaaa tatagaacaa tataccatct tagtaaaaga
     1801 gaacaatcat aaaattcaaa tcattgataa aaatttaaat ataaatgaac aagttttcat
     1861 ttacaaagca acaaataatt tactaacact gcgctctaat aaaaaacaat tagattacac
     1921 ttttagtttg gattctccaa aaaagctcgt atttattttg acaacgaatg atgggacaga
     1981 agggacagct aaaccaattg aattttttaa agctgattga tgaatagttg tttgatatta
     2041 caaaacaata atttcaccga aggtgaaaca agcgaaactt tacaaaaagt ggctagcatt
     2101 tgctagcctt ttttgtattg cggagcgtga gttttgaggg ggattcaagg gggagtttct
     2161 cccctttgac aagcggttat ttgcaccaaa tacgaaggta tttggctagc aaatatagag
     2221 cttgccaaac cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca
     2281 aacgatacgt cctatggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat
     2341 ttggctagca atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt
     2401 cgagtgagcg aatccgaatt tgcaaatctg aagctttgca aatgagtgtg ccggcttccg
     2461 taaaagtcta ggtaacatta gtcgatatat acataaggct ctaatttgcg ttttaaggcg
     2521 ttttaaacgt tctggtatgt aatttatacc aaagcgactt taaaacgcct taaaacgaat
     2581 tttataggtc ttgtaggacg tttcagggtt gttagggctt gccctgaccg cctgtaaggc
     2641 gctttaaaaa caagataagg gattttatct agacttgtct taaaacgccg tagatgagcg
     2701 ctcagagctt cttaaaggac tccttacgaa ctgtttttaa gcaaaggagc ctttaggcga
     2761 ctgcgcagtt caatgtgaga gcgtagcgat cacaccttta aagcgaccgt agggagcaga
     2821 ttcccagttt aggaaatttc gcgaacctgt ttggagaaaa aaagtaggaa atttttaggc
     2881 gggaaatttt gcccccctct tttataatct cttttataac ctctttttaa acctctttac
     2941 cgtcggctgt atccttactc tcccaaggcc tgtagctttt ttagggcatg aaattatctg
     3001 tttataggca tgaaattatc tgtttatagg catgaaatta tctgtttata ggcatgaaat
     3061 tatctgtttt aggtattgtt ttaagacata atatacctta aaattatgtc aataaaatta
     3121 gttagactgg agtatcaaat aaatggcaaa tgaaatcgta aaatataaac cagaattaaa
     3181 taccattcct ttaaggaaat ttactccaat agaaatgaac ttgttttttt ctattgtttc
     3241 tagaatgcgt gataaaggta atcaaaaaat acgcttttat ttcgatcagc ttaaagattt
     3301 aagtgcttat aagcaaactg ctggagaagt ctttataaaa gatttaacaa gaacatacga
     3361 tcatttaatg gatttacgtt ttggaaaaaa aagcaatggt ggattaacca tagaacgatt
     3421 tacaatgttt actgattttg aaattcatgg agaagccgat aacccttatg tggatataaa
     3481 agttcacgaa aaagctttgc ctttacttaa caatttagaa agttgggtac gtttctcttt
     3541 aacagaattt cgagatttaa atagcagtta tgctaaaaca atgtttagat tactaaaaca
     3601 ataccgaaca caaggatggg ctgaattttc caaggaagat tttttagaac tattagatat
     3661 tcctaaaagc tatagacaaa caaatataaa tcagtttgta ctcaaaccca taaaagaaga
     3721 actcacacca ttatttaaag gattaacgat tcgtaaaaaa tatggtaaag gccgaggcaa
     3781 acctgttatt ggttatcgtt ttacttggaa agctgaaatt aatcatgctg acgatttttc
     3841 aaaagggaag caagaagatt tacgtacaaa attatttaat attgaacaca atggagaatt
     3901 aacgcaagaa gaaaaatggc gcgctaaaga tcgaatacta gatcttccgt taggtactca
     3961 tgaagctaat tttaaaaaac aacaacaaac tgaaaaagaa gaagtggaaa aacaaacact
     4021 ttcaaacgaa cttaaacaag atttattagg aaatttacaa aacttattcg attaaagtat
     4081 aaggagtatt tatggcagat aaaacgatca aagaccttgc tgaagaatta ggagttagta
     4141 agacagctat taacaaaaaa gtttctgacg aaaatcgaaa actttggttt gcgaaaatcg
     4201 gaaacaagtt tgtgattaac gaaatcggtc aaaaagctat aaaatcaatg ttttttaccg
     4261 aaaacgaaaa ctcaaatcaa caaccagttg gcgaaaaatc gaaaaccgaa aaccataaaa
     4321 acgccaacca agtttccgaa ttagaactct tttttttcct agaaaaacaa ttaaatcaaa
     4381 aagatataca gctacaagaa aaagacgaac aattaaaaca aatgcaaaaa ttactcgacc
     4441 agcaacaaca actcacctta caagccaatc aacaaatcaa aaaacttcac gaacaactcc
     4501 agctaaccta tgcagaagaa tcttcagaaa aagaacccct ttctgttact gaagaaactc
     4561 aaaaaggaca aaacaaggag aaaaaatggt ggcaattctg gcaataaccc aacaattttt
     4621 attcataaaa attgttgggt tactttcttt ttttgctttt acaagcatag cgacatgatc
     4681 tcacgtcgct attttttaaa gagcataagg aaacgcggta tcactttctt acgaaaggtg
     4741 ctaggtaggc tgtgcctacc acgtttctaa gaaaaaaatt tgctatcact ttttcgccat
     4801 tgtggctagc ttatgtatag tatttcggta aaaaacagct atacaaatac tatatttgta
     4861 tgatatacat aaattataca cacataagaa aggacgtttt ctatggacat tttagttcga
     4921 aatatcaatc caaaaattat tacaagagta gataaacgtt gtcaggaact tacaaccaaa
     4981 acaggagaaa aatggagtcg aaataaatat ttaaaagtgc taatcgaaag tgattttgac
     5041 cgtcaactta tgaattacaa aaaagagcaa ttcgatttat tactcgaaaa atttatcgat
     5101 attcaaacaa aaaatactga aacattgaac gactatgttc atacaaacaa ccaactcatt
     5161 gaaacactta tcggaggaat ataacatgag aaaaacttct gttcaaaaac acgttaccct
     5221 ttatcccagt cacattgacg ttttagattc catcatcgaa aaaaatccag atatcaataa
     5281 ctactcggaa gccattcgct ttttatgtat gagttatgaa cctgatacca atacaacaac
     5341 taccagtaac caagccaaac taaatgcgat gggaaaagaa atttctatca tgaccgaaat
     5401 tatcgcagaa tttgctgatt tgtatttaaa agatacaggc gttcttatcg gtacaaactc
     5461 gaaagtatat caagaagtaa aagaaaaaat tgaaaaacag ctaaatccct cccaacgaaa
     5521 tcaaccaaag aatcgtcaaa aagaaacgag tcaaacattc acttctaaaa atttcgaccc
     5581 aaccaacttt ctaaaaagat aaaaaaataa accaggaaat ttttaatttc ctggtttatt
     5641 ttctagagag cggtcttcca ataagatttg caaatcgatc ccaatttgcg taaaaaaaaa
     5701 gctgctcgta cgagcagcta aacaagaaaa agtcagcttg ttttaagggt aaaataagtg
     5761 taacaaattt tgcgaatgca acgatctttt ttattatacg caaacaatc
//
LOCUS       DAFTHM010000133         5795 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFTHM010000133 DAFTHM010000000
VERSION     DAFTHM010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.134"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..163
                     /locus_tag="L7C88_002567"
     CDS             <1..163
                     /locus_tag="L7C88_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014862476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559356.1"
                     /translation="QNYDAFSSSLRRNNIKPFLEIGDEPGPSIIRLYLREDIEKYAKQ
                     LEEKRQKRQ"
     gene            226..648
                     /locus_tag="L7C88_002568"
     CDS             226..648
                     /locus_tag="L7C88_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014862359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559357.1"
                     /translation="MNKKYIVSVGSIVLIVLAIIAFSVSNKTETQPQNTVQSTTTSQS
                     SDHSVYPSLNSLKETHGQDLIDLGSSQITTVLFEKKNIAFITPKEGTDLEFSIKVTNT
                     KENLFSIPDIQYTPNKLKIGDTFGLAKVNEQYFAYSLK"
     gene            complement(742..1059)
                     /locus_tag="L7C88_002569"
     CDS             complement(742..1059)
                     /locus_tag="L7C88_002569"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559358.1"
                     /translation="MPVKGTSNFDFEIFYVDDEICGVFNKQKYTKEQAIEAWKNELFD
                     PEEEISFVVDESFVGWYHGNAEEEEVHYAGWWLEEGEPREQSVPVWVISENPLEEIEK
                     LEK"
     gene            complement(1086..1292)
                     /locus_tag="L7C88_002570"
     CDS             complement(1086..1292)
                     /locus_tag="L7C88_002570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559359.1"
                     /translation="MNWLKNEAELYVFHEEMQEKHLVPNVRNYLFWLEEKNDAQVFGK
                     SAQSPKIKLQLTSKQWNEHEWYIY"
     gene            complement(1273..1455)
                     /locus_tag="L7C88_002571"
     CDS             complement(1273..1455)
                     /locus_tag="L7C88_002571"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559360.1"
                     /translation="MTKCERVSVTISFIALLLSVISLLNTAIFIGQVEKQKEISLSEW
                     RYEEVNEGMNNELVEK"
     gene            complement(1469..1819)
                     /locus_tag="L7C88_002572"
     CDS             complement(1469..1819)
                     /locus_tag="L7C88_002572"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559361.1"
                     /translation="MKKSYKVFENNEIKEQEAIILSAQTPEEALEQALPFLVESQNIV
                     VEELPEFDSKIVFSFNCKKESEISVSPEFYCRSDISVEGLVMCASAFIEIFANHLQIS
                     VKELLDLLQEITNE"
     gene            complement(1845..2147)
                     /locus_tag="L7C88_002573"
     CDS             complement(1845..2147)
                     /locus_tag="L7C88_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559362.1"
                     /translation="MLSKQEKKYIRQKMYAMIGNRAITELSSEELLQVQQLAQIIGSN
                     SIFDSNPLPEMTLETLTAKRYKELRAIGYRMIDIRRALRISDTKFREWRTSNGLAN"
     gene            complement(2150..2383)
                     /locus_tag="L7C88_002574"
     CDS             complement(2150..2383)
                     /locus_tag="L7C88_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559363.1"
                     /translation="MTISVGNKVKYIGTAIPRYTNKLVVVKNILVNGLILEYPKEDRR
                     KVVVEGNGTWNMNSFICGFTEVEVTNDNENRSG"
     gene            complement(3369..3691)
                     /locus_tag="L7C88_002575"
                     /pseudo
     CDS             complement(3369..3691)
                     /locus_tag="L7C88_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3814..4929)
                     /locus_tag="L7C88_002576"
     CDS             complement(3814..4929)
                     /locus_tag="L7C88_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBP9559364.1"
                     /translation="MATKRFTATRKYNELYYQFPKVFITSEKYRSLSDKAKIAYMVFR
                     SRLDLAIQRNQVDSQGFVYFEFTEQELANALNCCRRSVNTIKKELKEYELLEIEDMGF
                     DQQTGKRNKARLYLGELDTTENDVYSLGPVDSTSVDSAQGKEEEESVDNLAIFDDFDE
                     KNPCENSAQLFNNSSNNLDTENLDTKIDTTSPVEMADDWQKEFIAHYSESTFVPKDVL
                     TWIVRSSAEWREAKEQLNMIYDSKRIIEKRQRKYNQTHGLSDGSEYRILGETFAEDLS
                     KTYQRCIQNEKIARHEGKAIQNRKGFYFRALLNFWECCVRELNLDPMATKLSDQAEYS
                     LLQAKRSCSYEDLETQIYGLSQLPKISMHNWLEELDT"
     gene            complement(4935..5333)
                     /locus_tag="L7C88_002577"
     CDS             complement(4935..5333)
                     /locus_tag="L7C88_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBP9559365.1"
                     /translation="MVKNKFRATDVLTQATFHMPKLFFIKSSKYYAMTAQAKYAYSLL
                     NEYLEESLIEKRIDEKKHVYISYTNQELAILLNVSEEEIEEIKNELEDYDLLTIEFGR
                     IYLKELIATMEDVRVYQHQNSFLIYGQDEV"
BASE COUNT         1694 a         1169 c          764 g         2168 t
ORIGIN      
        1 acaaaactat gatgcttttt ctagctcttt acgtagaaat aatatcaaac catttctaga
       61 aataggcgac gaacctggtc cttccatcat tcgcttatat ctaagagaag atattgaaaa
      121 atacgcaaaa cagctcgaag aaaaaagaca gaaacgtcaa tgaggcgttt tctgtcttgg
      181 atttacaagt aaaacaataa taaacacttt tacaacggag gttctatgaa taagaaatac
      241 attgtttcag ttggttcaat cgtactgatt gtactcgcta ttattgcttt ttctgtatcc
      301 aacaaaacag aaacacagcc acaaaatacg gttcaatcga ctactacaag tcaatctagc
      361 gatcattccg tctatccttc actaaatagt ttaaaagaaa cgcatggaca agatttaatt
      421 gatcttggtt cttctcaaat tactactgtc ttatttgaaa agaaaaatat tgcgtttatt
      481 actcctaaag aaggaactga ccttgaattt tctatcaaag taacaaatac caaagaaaat
      541 ttattctcca ttcctgacat tcaatatacc cctaacaagt taaagattgg ggatacgttt
      601 ggtttggcta aagtaaatga acaatacttt gcttactcac tgaaataagt ttctaatagc
      661 aagaggaaaa accctcttgt tatttttatc acataatcat tttataaaaa cgcttcgaaa
      721 atatcaacat ttttgaagaa actatttttc taatttctca atttcttcca agggattttc
      781 gctaatgacc catacaggca cagattgctc tcgaggctcc ccttcttcta accaccaacc
      841 tgcataatga acttcttcct cctcagcatt accatgatac caaccaacaa aggattcatc
      901 tacaacgaat gaaatttctt cttctggatc aaataattca tttttccatg cttcaattgc
      961 ttgttctttg gtgtactttt gtttgttaaa tacaccacaa atttcgtcat ctacataaaa
     1021 aatttcaaaa tcaaaattac tcgttccttt tactggcatc ttaacttttc ctcctttgac
     1081 tcacttcaat agatatacca ctcatgttca ttccattgtt tactagttaa ttggagtttt
     1141 atcttagggc tttgtgcact ctttccaaaa acttgagcgt cgtttttttc ttctaaccaa
     1201 aaaaggtaat ttcttacatt cggtactaaa tgtttttcct gcatttcttc atgaaaaaca
     1261 tataattctg cttcattttt caaccaattc attattcatt ccctcattca cttcttcata
     1321 ccgccattca gatagtgaga tttctttttg tttctccact tgtcctataa aaatcgctgt
     1381 attcaacaag ctgatcacac ttaataataa agcaatgaaa ctaatggtta cacttactct
     1441 ttcacatttt gtcattttgt ttccttcttt actcgtttgt tatttcttgt aataggtcta
     1501 ataactcctt caccgaaatt tgcaaatggt tcgcaaaaat ttcaataaaa gcactcgcac
     1561 acattaccag accttcaact gatatatcac tgcgacaata aaattctgga gaaacactga
     1621 tttctgattc tttcttacaa ttgaacgaaa aaactatttt tgaatcaaat tccggtaatt
     1681 cttccacaac tatgttttgg gattctacca agaaagggag tgcctgttct aatgcttctt
     1741 ctggtgtttg agcagataga ataattgctt cttgttcttt tatttcattg ttctcaaata
     1801 ctttataact ttttttcatt gttagttcct ctttcattcc tctctcaatt agctaagccg
     1861 ttactggtac gccattctct aaatttagta tcgctaatcc ttaatgctcg tcgaatatca
     1921 atcattcgat aacctattgc acgaagttct ttatatcttt tagcagttag cgtctctaac
     1981 gtcatttcag gcaatgggtt cgaatcaaaa atagaattcg aaccgattat ttgggccaat
     2041 tgttgtactt gtaacagctc ttctgaactt aattcagtga ttgctcgatt gcctatcatt
     2101 gcatacattt tctgtcgaat atacttcttt tcttgtttag acaacatttc tatccactcc
     2161 tattttcatt atcatttgtt acctccactt cagtaaatcc acaaataaat gaattcatat
     2221 tccaagtacc attcccttca actacaactt ttctcctgtc ctctttcgga tattcaagaa
     2281 tcagaccgtt taccaatatg tttttcacta ctactaattt gtttgtatac cgtggaattg
     2341 ctgttccgat atacttcact ttatttccta cgctaattgt catttcctca ctcctattct
     2401 tttttatcca aaactttttc ctgtcctatt cctgccaacg aatatacttc actgcatgct
     2461 taaacaaaac aaaatgttgc cctgttttat ttccgtcttt tacttgttcc acatacagtt
     2521 catatttggt cacacctttt aaaacgccag atactttttt tcatccattg tcacaattag
     2581 ttttttcatc aatcgattga tactgcactg ctcatttttc ttgttcatat agtattcctt
     2641 tctttttcaa aactagcctc ttttgtttac tagttttcat caatcatcaa cgatttaaca
     2701 gattttttct ttcgcagggt ttctagcgtc agcaacccca aactctaaaa aagtgccttt
     2761 gctcccttga aaaacgagcg gacgattgta ctcgtcatca tatgtttttc atactacctg
     2821 atccacgcaa ataacctttt tttgttctgt gccacaccca tccatacgta tcgcttgaga
     2881 ttcaccatac ttttttaggt ggtttatcct tcctaagtcc ctgttagaca cgctgattaa
     2941 cttagaaagt cctgtttgta tccaattttc aaagatctcc caaaagaaat aagtaggttt
     3001 acgtgtatcg cttctgttca aagtacctgt ttgtacttga gtatttctac tcccctcgtt
     3061 caagggattc cttccaccag ctagcttttc ctttcatcat caaatgttcc tgaaaagcat
     3121 ttacgtttcg tgtccgtgtg cttacttatt cttttttcga tagcgattat ccgctcgcta
     3181 ctcgctattt tatactttgt ttgttagctc aaataaaaac taacaaacaa aaaaggctag
     3241 tttctttccg ttttattttt ttaactgtcg ataaatagtt gttagtttaa ttccaagttc
     3301 taaaaccaat acgcccaaca aaaccacagg aaaaacaatt ggggcaaaca agtaaaatcg
     3361 gatagttttc atgtcttccc tctttctttt tggtgtcgct gtggtcgttc ttgccgttca
     3421 atacttcgat acatttttta ttcattattt gctcgttttg ttttcctctg gactgctttt
     3481 cttgcttttt gaatacttta tacgcttttc gtgcctgaat taataggtct tgtcggcgtt
     3541 tcattcgtga gaaaacaata tttgaaacca tcaaatcctg gttcgaacaa ccacgattcg
     3601 caataatttt cccatcaaaa aaaatagttt tcacttgaga aaaaaacagt tggaaatctt
     3661 gttttgttgc taattttttt gtcaaaatca ctgtgctttt ccctgttgaa tctacaatga
     3721 ttcttcgaac aatccgattc gataacttcc aacgttgccg attaaacaat gttacttcac
     3781 aacaaatatg acgtaagtga ttaggggtca ttttcatgtg tccaattcct ccaaccaatt
     3841 atgcatcgaa attttgggca attgtgacag cccataaatc tgcgtttcca ggtcttcata
     3901 actacaagaa cgcttggctt gaagtaatga atattctgct tgatctgata gttttgttgc
     3961 cattggatct agattcaatt ctcttacaca acattcccaa aaattcaata gcgctctaaa
     4021 ataaaatcct tttcgattct gaattgcttt tccttcatga cgagcaattt tttcattttg
     4081 aatacaccgt tgatacgttt tgcttaaatc ttctgcaaat gtttccccta aaattcgata
     4141 ctcgcttcca tcagataaac catgtgtttg attatacttt cgttgccgct tttctataat
     4201 tcgtttactg tcgtatatca tgtttagctg ctctttcgct tcacgccatt cagctgaact
     4261 gcgaacaatc catgtcaaaa catctttcgg aacaaacgta ctttcgctgt aatgagcaat
     4321 aaactctttt tgccaatcat cagccatttc aacaggacta gtcgtatcga tttttgtatc
     4381 tagattttct gtatctagat tgttagaaga attattaaat aattgtgcag aattttcaca
     4441 tggatttttt tcgtcaaaat catcgaaaat cgctaaatta tcaacagatt cctcctcttc
     4501 ttttccttgt gcagaatcta cactggttga gtcaacagga cctaatgaat acacatcatt
     4561 ttctgtcgta tctaattctc ctagatacaa ccgagctttg tttctttttc ctgtttgttg
     4621 atcaaatccc atatcctcta tttctagtag ctcatattct ttcaattctt ttttgattgt
     4681 attaacagaa cgtctgcaac aattcaatgc attggctaat tcttgttccg taaattcaaa
     4741 ataaacaaaa ccttgactat ctacttgatt tcgttgaatg gctaaatcta agcgtgaccg
     4801 aaaaaccata tacgcgattt ttgctttatc agacaatgag cgatattttt cacttgtaat
     4861 aaataccttt ggaaattgat agtataattc attgtattta cgagttgcgg taaatctttt
     4921 tgttgccatc gttattacac ctcatcttgt ccatatatta agaaagaatt ttggtgttgg
     4981 tagacacgaa catcttccat tgtagcaatc aattctttta gataaattcg accgaattca
     5041 attgttagta agtcgtaatc ttctaattca tttttgattt cttcaatttc ttcttcagac
     5101 acattgagta aaatggctaa ttcttgattg gtataagaaa tatagacatg tttcttttca
     5161 tcaatccgtt tttcaattaa ggattcttct aagtactcat tcagtaagct ataggcgtat
     5221 tttgcttgtg cagtcatcgc ataatatttt gacgatttta taaagaatag ttttggcata
     5281 tgaaaagttg cttgtgtcag cacatctgtt gcgcgaaatt tgttttttac catatttttt
     5341 cctcctagaa aaacacgcaa aaaaagctct gtataaatcg aattacacag agtttcttct
     5401 tgttgatatt taatttctaa aatacgtttc gggtaaaaac taaacactta ctaatattta
     5461 gattgtagaa tcttcgcctt catttattca ttttaaagag aaaaagatca agtgaaatgt
     5521 gcccaaaagt ttgattctat taatttttaa acaccattca taatatattt cctataatgt
     5581 aaaaagcgtc gatacttatt aaagcatcga cgttattttt atagtaaatt tatcaaaatt
     5641 tttgccaaca ttttttccga tttttttccc tatttctatc tttccttatc tttcttagtt
     5701 aatattattt gatgttaata tatcactact aatattaaaa aacattgatt tatcatagga
     5761 taaagagtga tagtttaata cttaaagaga catat
//
LOCUS       DAFTHM010000134         5568 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFTHM010000134 DAFTHM010000000
VERSION     DAFTHM010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.135"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            105..1094
                     /locus_tag="L7C88_002578"
     CDS             105..1094
                     /locus_tag="L7C88_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBP9559366.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1076..1537
                     /locus_tag="L7C88_002579"
     CDS             1076..1537
                     /locus_tag="L7C88_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBP9559367.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1587..2051
                     /locus_tag="L7C88_002580"
     CDS             1587..2051
                     /locus_tag="L7C88_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBP9559368.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2065..2814
                     /locus_tag="L7C88_002581"
     CDS             2065..2814
                     /locus_tag="L7C88_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBP9559369.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2814..3644
                     /locus_tag="L7C88_002582"
     CDS             2814..3644
                     /locus_tag="L7C88_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBP9559370.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3644..4291
                     /locus_tag="L7C88_002583"
     CDS             3644..4291
                     /locus_tag="L7C88_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBP9559371.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4389..5165)
                     /locus_tag="L7C88_002584"
     CDS             complement(4389..5165)
                     /locus_tag="L7C88_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBP9559372.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5309..>5568
                     /locus_tag="L7C88_002585"
     CDS             5309..>5568
                     /locus_tag="L7C88_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9559373.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQG"
BASE COUNT         1913 a          773 c          996 g         1886 t
ORIGIN      
        1 aaattgttat aaaaaaattt ttttgaaaaa tagtattgca aaataaagca atttcataga
       61 taataggtat tgtaaagtta tatgacttta taatacttat tagagtgagg gataaagaaa
      121 tgagacaact acacaaagaa cagattgaaa cagcaatggc agcgttaaag gaaaagacaa
      181 ttgatcatgt atattttaca gcatgtgggg gttcacaagc cgttttaatg gctggtcaat
      241 atctatttga taaagaatta actgtacctt gtcatgttta tactgctaac gaatttaact
      301 atgctatacc aaaaggatta tctgaaaatt ctttagttat cacttgttcc cattctggca
      361 caacaccaga aactgtagaa gcaacaaaaa aagcaagaga atttggagca atgactattt
      421 gtttatctaa tgaagaagga tctcctctat gggaagcagc tgaatatcct gttcactatg
      481 attggggtaa agatgttgat gctagtgatt taaataaagg aattctttat ggtttattat
      541 ttaatatttt acttgtttta gatggctcta aaaaatggga aacttgcttg aatgaatttg
      601 ataagttaaa tgatcttgtt attgctgaaa agagcaaatt tgaaataact gctaaagaat
      661 ggggtaaaaa ccaaaaacga gataaaatta tttacacaat tggtagcggt atcaattacg
      721 gagaaattta ctccacagca gcttgctggt tcatggaaat gcaatggatt aattctaatg
      781 ctattcattc tggggaattt ttccatggtc cttttgaaat cactgattat gatgtaccat
      841 tcatcttagt gaaaagtatt ggagatacaa gatttttaga tcaacgggta gaagacttca
      901 ctaaaaaatt cagtaataaa ttaatggttt tagaccaagc tgattttgac ttagaatcta
      961 tagatagtgt agcgaaagaa tatattgcag ctgtacttag tggcgttgtt attcgccaaa
     1021 tggtagaagc gattgctttt gaaagaggcc attccttaga tgttagacgc tatatgtggc
     1081 aaatgaaata ttaattaata ggaggttgca aaagatggca aatcaattat ttcacattgt
     1141 gattacaaca cattctaccc tttgtgaggg ttatttaaag gcaacaaaat taattttaat
     1201 gaatgacgcc acaggtatta gtgctgttcc atttaaagaa aatactagtc cagatgattt
     1261 tgaggagagt atgaaagaaa taattagtca gcatcatttg caacctctaa ttattttaac
     1321 ggatttaatt ggaggaacac ctaataatgt ttctattaaa cagttgaaca acaatagaat
     1381 tcaaattatt gctgggatta atttacctct tttactggag ttattaatgg cccagtcagc
     1441 tggtaaatct atagaagaaa tagattttaa ggaattactg aataactctc aaaaaagtat
     1501 ggttcatatt aattcgcttt taaaagatgt cagttaaggt ggcaatttct attctataaa
     1561 ttttaaaaat tgaaggagga aatagaatga ttaaattagt gcgtgtagac cacagattac
     1621 ttcatggaca agtaatattt tcttggacta aacagtatga tattaaccat attattgtgg
     1681 ctgataacaa agttccagga gatccaatgt ctgtgatggc tttgacaatt gctaaacctg
     1741 ctgattgcaa attagacatt gttaaaatta gtgatgttaa agggattatg gaaacatccc
     1801 caaatgataa ttacatgatt ttaattaaag gacctaagga agcttttgaa ttagttcaaa
     1861 atttaccaga aattaaagaa attaattttg gcggtgtgtc taagaaaagc gagtccaaac
     1921 aatatggaaa ggcagtcttt ttaactcctg aagaattaga agccacaaaa aaaattcttg
     1981 atcaagaagt gaaaatattt gtgcaacaag tcccatcttc aagtattgaa aatgtagatt
     2041 ttagtaagta aggggggaaa ataaatgtta ttaaaagcca ttttattagg tttagttggt
     2101 gtggtagctg ttattgactc caggttaatt ggtcgacaaa atattggtag accactaatt
     2161 ttgagtacac ttgccggact tgtgctaggt gacttgcata cagggattgt tcttggggca
     2221 tctttagaat taatttctat gggattcgtc tcaattgggg cggctggacc tcctaatatg
     2281 caacttggta gtattattgc cactgctttt gcaattttaa ctaatagtag tacagaaaca
     2341 gccttaacaa tagctatccc agtggctgta gctggtgaat ttatgagtat tatcatgcgc
     2401 atgataattg ctcaatttgg acatgctgca gataaagcca ttgaaaataa taaatttaga
     2461 aaagctcaaa ttattcatat ttattggtca tttattttta atgcttttgt ttactttatt
     2521 ccaatctttt taacagtata ttttggtgct gacgttgtgg cagatttagt agataaaatt
     2581 ccagaaatga ttacagacgc cttgactgtc tctggaaata tgctttccgc attagggttt
     2641 gcaatgctat taagcacaat gttgagtaaa aaattatatc cttactttat ttttggattc
     2701 tttattgttg cctattcagg tctttcacta attggcgtga caatttttgc agctctgatt
     2761 gcctttgtaa tggatcaagt taaatatgga aaaagagaag aggcgcatgg ttaatggaaa
     2821 atagtacaga aaaaaaacgt ttaatcacaa aaaaagatct taataagatg tgtcttcgtt
     2881 catggacaat catgtgttcg tggaattatg aaagacaaat gcatatggga tttatgtatg
     2941 ggatggcgcc aattttaaat aaagtttata aaaatgatga agagaaaaaa agagaagctt
     3001 atactcgtca tatggcattt tttaactgta cgcctcaaat gacttcattt attatgggac
     3061 tttgtgcttc tatggaagaa caaaatgctc aagcagaaga aggaaacttt aatactgaat
     3121 ctatctccat gattaaaacc agtttaatgg gtccttttgc tggaattggt gattcatttt
     3181 tccaaggtac tttaagaatt attacatttg ggattggatt gtcttttgct aagcaaggta
     3241 gtattttagg accgatttta gctgttggcc tttttgctat accttctatt ttagctgttt
     3301 tttacggcgg taaattagga tatgagtctg gcaataaata ccttactaaa ttgtatcaag
     3361 aaggtcttat ggatcgagta atgcaatttg cttctatcat tggtttggct gtagtaggtg
     3421 gaatggtggc tagcatggtg ccaattgtca cccctttaaa attcactaca gggggaacag
     3481 aacttgtttt acaagactta cttgattcca ttattcctgg attattacca cttgtatgta
     3541 ctttgggaat atataaattg attaagaaaa atgttagtac aaatatgctc ttattaggtt
     3601 gtattttggc agggtttgtt ttaagtataa taggtatctt ataatgatta aggctctaat
     3661 ttttgatatg gacggagttt taattgatag cgagattatg tatcaaaagt gggtatttaa
     3721 ttttttaaaa caagaaaatt taagctatcc tttgtattct tatcaaaaaa agattggaac
     3781 tacagcaagt atttttgatg atatagaaaa gtacaatgag ggatgtaaca gtttagaatt
     3841 gaagggaaaa tttactaaat attggaaatc gcaaaagatt gattacttgg atatttttcc
     3901 taatatacta attgaacagc ttgaatggtt aaaaaagaaa aaaataaaaa tggcaattgc
     3961 ttcttccagt ccaatggata ctataaatga agttgttacc acttgtaaaa tagagtcata
     4021 ttttgattgt ttaattagcg gaagagattt gccagaaagt aaacctaatc ctactatatt
     4081 ccttaaagct tcagaacagc tcagaattcc agttgaagaa tgtctggtga tagaagattc
     4141 ttataatggt ataaaagctg gtaaaagagc aaatatgaag gttcttgcaa ttaaagataa
     4201 acgtttttct caagatgtaa gtctagcaga tgatgttatt tacgatatta aatatctgcg
     4261 acaagaagta caggtgaaat ttggaatata aataagtttt ttgatgtatt tagagaatat
     4321 tagtaaaaat aaaaatcatg cccaaatcta atcaaaattg attgctttgg gtatgatttc
     4381 ttttaatatc aatctattac tttaggatct gaatcatttt tatgcaccgt atctaaagtg
     4441 atattttctg tgacttcaat aacataacta attctatcac aacgaactgt ggattgagaa
     4501 taatgaaatg gttgattatt tttatctttg ccaacctttt ctaaaataaa tagcggatct
     4561 cctactatac attgcaataa gtcggaaagc tcaggtgttg cagataaacc gtttatttcc
     4621 ataatagagc tcgtagcttt gacatcatag tcatcttcta gaagtttata taatgaagta
     4681 tattggctac ctttttcaaa taaagttgga aatttttctt ctgatgcgaa aaaattatca
     4741 attcccatcg gggcaccgtc ttcccacatt aaacgtttaa tattgtaaac tctatcagtt
     4801 acattgattt gtaatttatt agctaaaaac tcatcagcct ttataatttt agaatgtaaa
     4861 acagtatatc taattttatg tcctcgggta gaaagagaat cgctaaatcc atgaactcca
     4921 gctaatttta aactttcttt tttttgagtt acaaaggtcc ctttccccct taatcgttca
     4981 actgttccac tttctgctaa aagtttaaaa gcttttcgaa tggtaatctt acttactcca
     5041 taaattttac ataattcttc ttctgtaggt aattgctctc ctggaagata ttttttttca
     5101 cgaatatcgt tacgtataga agcttctact tgtaaatata atggtctatt atcttgaaaa
     5161 ttcatagtac actccctaaa aagttatact tcattatatc acaatttatt aaaacgtcga
     5221 ttgtaaaatt aagctagaca actaaaaaga tcatttgtgc tacactcaaa atagttccga
     5281 ccaaagaatt aataaggagt gagtacaaat gacttacacc catcttacaa cagacgaact
     5341 agtaatcata gagtcttatt tcaatatcga gaaacctgtc gctcttgtcg cacaaagttt
     5401 aaatcgctct agacaaacca tttataatgt ttattcgttt ctcaaacaag gaaaaaaagt
     5461 gctagattat taccgtcaat acaaacaaaa taaatctcgt tgtggacgac gttcaaccgt
     5521 tttatctgat gaacaatcaa catatgttca agaaaaggta gctcaagg
//
LOCUS       DAFTHM010000135         5418 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFTHM010000135 DAFTHM010000000
VERSION     DAFTHM010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.136"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..241)
                     /locus_tag="L7C88_002586"
     CDS             complement(<1..241)
                     /locus_tag="L7C88_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase"
                     /protein_id="HBP9559374.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQ"
     gene            complement(353..589)
                     /gene="secG"
                     /locus_tag="L7C88_002587"
     CDS             complement(353..589)
                     /gene="secG"
                     /locus_tag="L7C88_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBP9559375.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            complement(707..985)
                     /locus_tag="L7C88_002588"
     CDS             complement(707..985)
                     /locus_tag="L7C88_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBP9559376.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            complement(1098..2066)
                     /locus_tag="L7C88_002589"
     CDS             complement(1098..2066)
                     /locus_tag="L7C88_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBP9559377.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     regulatory      2281..2325
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            2349..3323
                     /locus_tag="L7C88_002590"
     CDS             2349..3323
                     /locus_tag="L7C88_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBP9559378.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     gene            3328..3903
                     /locus_tag="L7C88_002591"
     CDS             3328..3903
                     /locus_tag="L7C88_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBP9559379.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(3970..5109)
                     /locus_tag="L7C88_002592"
     CDS             complement(3970..5109)
                     /locus_tag="L7C88_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBP9559380.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT         1511 a         1124 c          994 g         1789 t
ORIGIN      
        1 actgtaaaaa atggatggct tttttagtgt ctgcccacca gctttctgct ttttcttgca
       61 aaatatcata tggctccatt gttccgtgtc ctttaaaaag cggcgcataa actgtataat
      121 ctgctttttc caaaaatcgt gcgagcattc gaacatcgtt tggacttcct gagtaagcgt
      181 gaagcagcaa aaccgctcgc tttccatgtt ttgcataaag gggttttggt aattgtctca
      241 ctcgtctcac ctctttcgcc tcattttacc atagtttctt tcataacttc ttcttaagcg
      301 ttctctttgc aataaaaaaa gccgcccgcc gttttgcgag aggcttattc aactacttcg
      361 aagataaata tgctaggaca aataataaga tcatccagat agctcccata actgcagttg
      421 atcgctgcat gacagcttca aagccgcgag ctttttgttt gccgaatagt tgatccgcac
      481 cgccggtaaa tgcactcgct gcactatttt gcttgcttgg ctgcatcata atcgcaatga
      541 ccataacaat cgataaaacg atcacgattc ccaaaattaa attatacata tcgcagcctc
      601 cttcccaaaa gatatcgtct ctttaacttt atcatagata aaagtccgtg acaactctat
      661 ataaatggaa taacagctga aagttcaaaa ctttcagctg ttattcttat gactgacgta
      721 agacgtcttg atattctggt ttcttttcaa actctttttt tgcataaggg cataaaggaa
      781 tgatcttttt cccgtctcgt cttgctaatt ctactccagt atacactagc ttttcagcta
      841 acttttgacc acgatatgct ggatctacaa atgtatggtc aatgatcatg atgtctgggc
      901 ccgcatctga ccatgtcatt tctccgatct cttgttgttc atcattgaat aaagcaagac
      961 gatttttttc ttctttgatt tccatatgcc gcactcctca aataactgat atttttttat
     1021 tcctacctta ttttagcagt ctcctgatct ataaacaatt atttatcctc gaattactta
     1081 caaaaaagaa gagaaaatta attcatcgtt attctttgtt caataaatga aaaaatcact
     1141 gtccaatagg ttttcggatc tttcatcgat gcttccaagt gttctgcttc tggaacaagc
     1201 agcagtgctt tatcccctgc cgtagcattt tgaatcgtgt acgctgcttc tgtagggaca
     1261 aaatgatctc tttcaccatg aatgaccaat aaaggcagat ggttgctgcc aagctgtctc
     1321 gtagctgatg cttgctttaa ggagtaaccg gcgtatttct gggcataatg attcgcatat
     1381 ctcatgacca tttttttagg aaagacagtg attttactta acatatatcg gaattctgca
     1441 taaacagaaa catatccgct gtctaaaata aatcctttga ccgctgatgg aagtttttca
     1501 ccacttgcca tcatgatcgt agaagctccc attgatccgc cgtgtaaaat aatggacgca
     1561 ttcggctgtt catctaagat gagttggatc caggcaatta aatctagccg atctagccat
     1621 cccattccga tgatttctcc ttcactttct ccgtgcgcac gtaaatcagg tacaagaacg
     1681 ttgaatcctt tctctgcata tcttttacct atatgagaca tgtctctttt ccctgtgctt
     1741 cggtaatcat gtacgcaaat gacccattta ttctgcttat ttggatggat gaacatctga
     1801 ccagctagtt tcaacccgtc ataacttttg attgttttgg gtgttccctg ctcccaaaag
     1861 ctttcacact cttcttctaa tttttgtcgt tttttttcta ctgacgtgac tgcagcaggg
     1921 tccatcaaac gatgaccagt gtcttcatac cagtcatatc ctctctgtac tcccgctctt
     1981 actaatttct ttgcataaaa ataagaaaga aaatggtaac tgatccctat aattatcaga
     2041 ataagaatga aataaaaaat aaccattgta cacccgccgc tttctgccaa actataatct
     2101 aactattatc caatgtaccg atccatagga ttctttattt tcggcacacg taaattccat
     2161 ttctttttca ttgtatcatt tacttaaagt tctcctcaat agatttactt gtaagagagc
     2221 atttacattc gcaataaaag ccagtatact aatttcgtgc attataatca agacgctcgt
     2281 cttggactgg ttcggaaact tcccagaata aaaaactaag tatctctaaa gaaaggagat
     2341 tggaaataat gcgaaaagta attattgatt gcgatccagg gatcgacgac actttagctt
     2401 tatcattagc tgtcaaatcc cctgatatcg aagtagttgc tattaccgta gtttgtggga
     2461 atgtccctgc agatataggt acgcagaatg tgctgaaatg cctggaacgc tgtgatcgtt
     2521 tagacattcc tgtttatcaa ggaatggaaa aacctttgaa gcaacctttc atcagtgcac
     2581 aagacactca tggtatggat ggtttagggg aaacaaattt cccgatgatc ttgagaaaac
     2641 aggcagaacc tctccatgcc gttgattttt tggctgatta tttcaaagaa aagacaaata
     2701 catcagtcat tgctttgggt cctttgacca atatcgcttt tgctttgaaa gtcaacccaa
     2761 atattgggaa acatatggat cgttttgtct cgatgggtgg aacttacaaa agccatggta
     2821 actgttcgcc agttgctgaa tacaattact ggtgtgatcc tgaagcagct tcttatgtat
     2881 tcgagaatct caaacaaacg atagaaatgg ttgggttaga tgtgacaaga gaaatcgtct
     2941 tgacaccgac tatcctcgaa tactgctgtc aaatgaatcc tgaagaggga gagtatctaa
     3001 aagcgatcac tcgtttttat tttgacttcc actggaaaca agaaagaatt ttaggatgtg
     3061 tcatcaatga tccgttagct gttgcttatt ttatcgaggg ggccatctgt gaaggtttca
     3121 aaagcttcac tgctgtggaa actcaaggaa taagtcgtgg acaaacattg gttgatcgtt
     3181 atgaattttg gcagaaacct gctaacagta aaattatgac aaaagtagat actcgtcttt
     3241 ttttccgaaa gtttttaacc gttcttttaa atgcacaaga agaaacgatt atgaaagatt
     3301 tggaaaggtt aaagatgggc taacaaaatg aataaaaaca aaatggcaac tcgcgtactt
     3361 acagtgatgg ctttgtgtat tgggatcaat tatattggag gaacgattgc tttatggctt
     3421 cgtttgccaa tctatctcga ttctatcgga acgatttttg ctggtgcatt gcttgggcct
     3481 gtacctggaa tgctgacagg attgtccagc ggtattttaa gtggagtgac tacagatatt
     3541 ttttctctgt attattcgcc aatccaaatt ctcacaggct tgcttgctgg attgattttg
     3601 ccaagatatc tcggcaaaga taaaaacagc ttgaaactgt tattactcgc tttgattttg
     3661 tcggtacctg gaacgatcgt ttcttcgatc attaccgttc agttatttgg cgggatcacc
     3721 tcctcaggat ccagtatgat cgttcagcta ttacatgggt taggtttaag tcagacaaca
     3781 agtgtgatct tggtacaggc aggtacagac taccttgatc gtttgttgtc tatcgtcgtt
     3841 gtttcattag tcatcactat gttgccacaa cgcttgatat attcaaaaag aaaaataggc
     3901 tgaataaaca gagctggatt agcaaaataa tgctaatctg gctctgtttt ttcatttatt
     3961 aaaaaaatct tacgctaagt aggataaaat aattccttga tatttttcaa tcatatccaa
     4021 ataattatcg atttcaacat actcatctac ttgatgaggc aaagtaacga caccaggccc
     4081 aaagacgaca aagtcgaagg aatggttagc tttcgtaaat tcggctgcat ccgttgttgc
     4141 tgccgctcca actaaaggta atggctggct gaattgttgc tgaatgcaat gaatcaaagg
     4201 agaatctgga tcagctttga caggtatttt gttgtaatcg atcatcaatt ccaaatgata
     4261 gtctgtctct tgattcaatt cattgacgat tgattgcagc aatgcaatga ttttatcatt
     4321 tgggtattct ggaatcgatc gaatgttccc ttggagctgc gcatggcttg ggatgctgtt
     4381 gacttgattc ccgccactga tcaatgtaac attatggatt gtttttccta ggacaggatt
     4441 ctcgattgtt tcagcgaggt gattcatttc agcatttgct ttcgtaatga attcatttag
     4501 gtgattgatt gcattataac cttggtctgg catagagcta tgcgcttctt ttccgtgcga
     4561 ggtgactgta tagttgattg atcccatgtg cgtatacatc aaactgtaat tagttggctc
     4621 tccgatgatc aaggcatcta agtcatctac atagcctgct ttcgtgagct gttccccacc
     4681 tagttcaccc acttcttctc cgacagtggc taataatttg actgttccgt taaatggttt
     4741 tcctgactct ttcagttcga tcatggcaat caccattgct gccaagccac tcttcatatc
     4801 tgtagcacca cgtccgtaca aacggttccc atggatttct gctgcaaagg gtgcataggt
     4861 ccaagacgat tcatcaccag ccgccacgac atccatatgc ccagataggc ctaacacttt
     4921 tcctgattgg cccttttggt aacgagcaat caaattatct ctaccatctc tgtaagaaac
     4981 aatctctcct gttatgtcat gctttgccaa aagcttattc aaataggctg ctacttcacc
     5041 ttcgtttcca ttcactgatt taattcggat gatctcttgt aaaatcgcga ttttttcttc
     5101 ttttttcatc taatcctctc ccttgccatt tctttttatt gtatttgagt gtgctcgaat
     5161 tttcaaatag gagcaaccaa agtaaaaatg aagaaagaga gccactttat gaaaaatatg
     5221 ctgctacttc cctcctattt tatttatacg agaggacttg ctcatagatt cctattctac
     5281 tgttctatcc ttaaaagctc ttatatgatg ctagttattg ttagctttcc tttttcaagg
     5341 atgatctttt cttgtaccat tctttgtaaa catcatatac agaagctagt tgcaaaaaaa
     5401 actctctacc tgctgata
//
LOCUS       DAFTHM010000136         5408 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFTHM010000136 DAFTHM010000000
VERSION     DAFTHM010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.137"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            139..477
                     /locus_tag="L7C88_002593"
     CDS             139..477
                     /locus_tag="L7C88_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559381.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(682..1257)
                     /locus_tag="L7C88_002594"
     CDS             complement(682..1257)
                     /locus_tag="L7C88_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBP9559382.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGF
                     YEWNEEKDKFMFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRMPLVL
                     TEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(1989..2570)
                     /locus_tag="L7C88_002595"
     CDS             complement(1989..2570)
                     /locus_tag="L7C88_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBP9559383.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(2753..3379)
                     /locus_tag="L7C88_002596"
     CDS             complement(2753..3379)
                     /locus_tag="L7C88_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBP9559384.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(3401..4732)
                     /locus_tag="L7C88_002597"
     CDS             complement(3401..4732)
                     /locus_tag="L7C88_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBP9559385.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(4887..5288)
                     /locus_tag="L7C88_002598"
     CDS             complement(4887..5288)
                     /locus_tag="L7C88_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBP9559386.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
BASE COUNT         1521 a         1172 c          895 g         1820 t
ORIGIN      
        1 actaaaaaaa taatccaaga aacattgaac ctatggatcc aaaagctacc caaatactat
       61 agctaacccc ccgctacctt caattttgca gataaaacgc tttgggagaa aatttcaaag
      121 acaacaggcc atcctatcat gcccgattat aaacaaaaag ctggctattc cttttgctct
      181 gacaaatttc aattgggaaa gttcacgaaa ctagcaggtg aagaagtttc aactgttcgg
      241 atcaaagaat gcccgcttca aatagaaaca ttggttcaac gaatttcaac tagacaagac
      301 tttgctattg tagaacgtga gatcgtagct atttttgtag aagaagggat tttacatgat
      361 ccaactcata tcaatgtgga taaatggcaa cctcttatct ataaattcag agaatataca
      421 actgccaacc agtcgttaac tttgaatttt agattccaag aattcaaaga gtcataatga
      481 taaacatcgt taggtataaa taaaaaagac tcgcagcacg agtaaaaaac aaatagaagc
      541 tatacattag aaaggtcgac tgtgacccta tagatgcagt atatgcagct tatgagcatt
      601 tcttctgttc tctttgtttt tgggatctgt gctgaagtct ttttcgtttt ttgccgctct
      661 ttctttgaaa aatcgattat gttatacctt ctccattact aattcaggca tctgctgagt
      721 aatgattttt cgcgcaaaag aaatatctgt tacccaaggt tcgatttgtt cttcagtcaa
      781 gacaagcggc attcggtcat ggattggtgc gactgtgcgg ttaggttcag tagtcattat
      841 gattgattct gccatttttt catcctgatg gctacgataa aaaccgccaa tatacactat
      901 tttttcctta tttgaaaaca taaatttgtc tttttcttca ttccactcat aaaagccact
      961 cattgggaaa acacaacgat tttgcaaaaa tggttgatga aaggtctttt tttcttctac
     1021 tgtctctgca cgggcattaa tcatcaattg tcctttttta aatccggtaa atccccactt
     1081 catgatttcc ggagtgagga tgttttcttc ctcttttctt aacgtcacaa caagatttga
     1141 cggaaaaact tctccagctg ctaattctgc tgcctgcttc ggttgtttcg tctgggcttc
     1201 tcgataataa ttctgaagga gctctgactc tagatcaaaa aaataacgac cacacatcct
     1261 aatccctccc aatctttttt tctatcatac actgcaacaa gaagttcgca ccaacaaaac
     1321 gctttcaatt tttgtagaac taaaaaagtt gtgacaagtg acaaactctc cagtgaatgg
     1381 tattctcctg ccaactcctc ggtcacaagt cacaatattc aacaaacatg agaagctgct
     1441 ttttgaaatt gttccttgtg actcggagtg aaacggcagg cttacgacct ctgggtaaac
     1501 ggtgttcaaa agccagtttc tcggtattaa gccaaattta tgcaaaaatg tagaaagcca
     1561 ttttcacaaa atttttctta atactcgaaa ctaagcgact ttttcacaac ctcttcctta
     1621 aacggtgttc aaaagcttgc atctgcggta ataagcccaa ccaaacgaaa aatatgagca
     1681 gctattttta tttggctgtt cttattactt gatgcagggc agctttttca caacctctcc
     1741 actaaacggt gttcaatcag ctaaccttcg gtattagctc aaaaaacggc aaaatatgag
     1801 gaactatttt gccgtttgtt tctctaatac tcaggtcaaa gcgctgattt cacaacctct
     1861 aatacacggt gttccagaag tagcttcttc gaaaaataag ccgaaatttc acaaaaattt
     1921 gagaagcaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc
     1981 tctaattatt aaagaacctt ttgcgaagtt aacaatcttt ctttgatcaa ttgaaaattc
     2041 tgcctaagta gtgatagatc ctgtgtgact ttcaacaata agatacttcc ctggatttca
     2101 gcaatcaacg ctttggcttg acggtctgct tcttcatcgg acagtttttc ttcagaaagt
     2161 gccaggatat tttgtttcgt atacttgacc cattgattga ctaattctag tagcaacaga
     2221 cggtattctt catccactgt actcaactca ataatcaaat tacctacagg acagccatga
     2281 taagtgatct gtgtctcatg atcagcgaaa atccagtcca acatttcttc taatgcttct
     2341 tctggctgtt ttccagcatt taagatgtct tcgaacaatt ctgtctgcca tacgtccata
     2401 tgcgcatgga tcaccgctag acaaacttct ttttttgaag aaaagtaata ataaaattga
     2461 ccttttcctg tatcagaagc tgctagaata tctcggattg acgtttcatg atagcctttt
     2521 ttataaataa gatctttggt cgcttccaag atcttttcct ttgttttcaa tgatattctc
     2581 ctttttcatt tctcatagtc ctatattata cagtaaattc atcatttttt cttcttaatc
     2641 gtttaaaaaa gactgtgcca aattatctga cacagccctc actataaaac tgttctcata
     2701 tagctagatg ttcattgatt caagaactgc gaggacaaaa gcaattccta tcttatgata
     2761 gttgctctaa tacttcctct gttgtcatca cttgatctgc aataaagcca aagttcgtca
     2821 acgctgcatc cattgcttct tggccaggag caccaattgc atctgtcgct accacaacat
     2881 tgaatccact ctctaccaat tcacgcatat gggaatcgct acacaagttt ccgttcattc
     2941 caccaagaat tactgtgtcg attccatttt ttctcaattg gagcgccaaa tcattgcttt
     3001 ctggtccaaa gattttatga ggagagctga tgatcgtatt ttcatccaaa taaggtttca
     3061 attcttcgat aaaatcggct cctgaacctt cttccactga ttcatattga ctttttctag
     3121 caaacatctg ctgctcaagc atcatatgtt ctcctgcacc gccaaattgc catttatggt
     3181 catgtgggta aaaataatga ggagaaataa agagtttgta tcctttttct tttgcttgtt
     3241 ttaccatttc aatcatattt tcgatcgtat tgtatttttc taagatatct tttgtcaaac
     3301 caaagccacc gcctgctggt ttcaagaact cgacttgcgg gtcagtgaga actactgctg
     3361 tatttttatt attgaacatg gtggattctc cattcgttat ttattttaat acatcattta
     3421 gagcttcact cattgtcgga tgagaataga tttgatctct caataacgta taaggaagtt
     3481 ttccattcat agctagcgaa atcaagttga tgacttcatg agaatcttcc gcatagatac
     3541 ttgcccctag aatcaagtca gtttcagggt cgactaaaac tttgaataca cctttaggat
     3601 cttctaatac ttgtgcttta gggacaccgc ttgtcatata cttgaataat ttgtaattga
     3661 cgccttgtgc tttggcttgt ttttctgtta aacctacatt ggataaagtc ggagtgataa
     3721 atacactgta aggcacagct ttccggttat tcgttgttcg tttattctcg cccttcaact
     3781 gatccataat gattcgataa tcatctagag agatataagt gaactgcaat ccgcctttga
     3841 cgtctccaat cgcccaaatg ttgtctgcat ctgtacgaag gtattcatcc acagcgattg
     3901 ctccgcgatc tgttagttta acatctgtat tttctaatcc aagtgatgct gtacttggtt
     3961 ttcttccagt tgcagccaaa acttttgacg cttggattgt tacttcttgg ccatcttctg
     4021 taaaggtgac ggcagctgtt gattcttggt ctgctacttg atctacagat acacctagat
     4081 ggaattcgat tcccgcattt gtcatgtctt ctaaaatcat ttgcgcgata tcttcatctt
     4141 cacgtggaag aaattcagaa tgggcatcaa gaacgacaac tttagatccg tattcattga
     4201 acattgatgc aaattccaag ccaatatatc cagccccgat gatcactaat ttttccggta
     4261 attgttcctg atccatcgct tgcgtagaat caatcaagta gcgacttgta ttcaatcctt
     4321 tgattggtaa aatgattggt tcagaaccag tattgatgaa aatccgttcg ccttcaacaa
     4381 tcactttttc accattattc gtcacttcga tttgatggtt agaaagaaaa cgtgctgtac
     4441 cgtccatcac tgtcccagtt gcctcatcgc tgatcatatg ataatttttg gcgcgaagca
     4501 tgcccgtcaa tttttctttc cgagcaacag cctctgtaaa gtcgattcct ctttctccat
     4561 tgaaaatcaa tgatttagaa ggaatacagc cgatgttgat acatgttccg ccatacatac
     4621 gtgttgactt ttcaacgact aaaaccgatt caccttttga agctaacgcc ttcgctaaag
     4681 tcttaccgcc ctttccaaaa ccgatcacaa tattttgata tttttccatc atttttccct
     4741 cgcttctttt ttacctaccg attggtacaa aaatatgata accgataatt gtctattctc
     4801 caaatcatct gctttatttg tcaaaaaaaa ccagacaaaa agcggtcctt tcacgttttt
     4861 agtctggttc gatttccttt attcttctaa acaatcgtta cttctacatc gatatttcct
     4921 ctagttgctt tggagtaagg gcagaattca tgcgcatctt ctgcaatttt ttgggcttct
     4981 tcttcgctga tgccatcgat atgcacttct aatactacac cgatctgata gccgccatca
     5041 tctaaattat aaagagagac acgtgctttt actgtggact ctgctgtcat tcctgcttct
     5101 ttgatcatat gttgtaccgc cccattgaaa caagaagcat aacctgctgc aaataattgt
     5161 tctggatttg ttccttctgc atggattcct ggaggagtga ttttcatatg catcgagcca
     5221 tttggtgcct cgacttctcc attgcgcccg ccatggttga tcattgctgt ttcgtatgct
     5281 tttttcattg tactgctcct ttcgattgac catttgctac ttggctataa ttatagtgta
     5341 tgacaagtaa ggcgctttct acaaaaattc tgcttattcg aataccagaa tgccgtcttc
     5401 tactattt
//
LOCUS       DAFTHM010000137         5338 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFTHM010000137 DAFTHM010000000
VERSION     DAFTHM010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.138"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(61..279)
                     /locus_tag="L7C88_002599"
                     /pseudo
     CDS             complement(61..279)
                     /locus_tag="L7C88_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(545..739)
                     /locus_tag="L7C88_002600"
     CDS             complement(545..739)
                     /locus_tag="L7C88_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559387.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(839..925)
                     /locus_tag="L7C88_002601"
                     /pseudo
     CDS             complement(839..925)
                     /locus_tag="L7C88_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2091..3131
                     /locus_tag="L7C88_002602"
     CDS             2091..3131
                     /locus_tag="L7C88_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBP9559388.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            3955..4287
                     /locus_tag="L7C88_002603"
     CDS             3955..4287
                     /locus_tag="L7C88_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBP9559389.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4906..5247
                     /locus_tag="L7C88_002604"
     CDS             4906..5247
                     /locus_tag="L7C88_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBP9559390.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1942 a          728 c          900 g         1768 t
ORIGIN      
        1 aggtattttt attatatata gatttaacat atgtcggtcg gttgattgat atagctaaag
       61 ttataactca accgaagccg attcatctac acgaataaag ttgcgagtgt tctcggctaa
      121 ttcataaaaa ttgttatgtg ttccatatag caatactgga ataactttat tttcttgaat
      181 ctcataagca actctataca cggtgaccgc atacttaaat ccattagacc aattacctga
      241 taaacctcca gttttttgct cttacttaaa tggatcaatg gcaatttcat cacaaaccta
      301 tagaggatga gtgacttctg cctaattacg ttaaaaaata ttgaaagtaa ctctatgtag
      361 caaaaaatat ctagaatttc atttcctcaa aactgatcga tattgtatct aaaaatatat
      421 actacctaaa ataggtagta tatattaaaa tatgtgcttt tgttagaaaa atcaatacat
      481 aaattatcat atctgtatat gtcatttagg tatttcagtt atgttataat agttttgctg
      541 tctgctaccc cggcctaatc tggcaagggg aggaggagat ataatgaaat acctttttga
      601 ttttgttttt gcaatcaagc cacttgcaga tgtagtgtgc agttacctct gcaaatggct
      661 tgattgcaaa attgccaaaa aagacagtaa gcctacccgt taattctata atatagaaac
      721 gtaaaaaaaa ccccatcagc ctgcacgctg atggggtttg gtgatataat gaaatacctc
      781 tttgttactc ataattgtac cataattagt cacgaatgca accaatagaa aaaactactt
      841 agaacggtag atcatcgcta ataacaatgc attgtccacc aaatggattt tgtgaagcat
      901 taaatacatt gttattaatt gtcgctgctt ttaactaggc ctctcccctt ctattataaa
      961 agaagatata tatcatttct taattaccta ctaccttaaa ccaaaattta agtactacct
     1021 aatttaagta ttacttaaac aatctaaaaa atagttatcc caattgttat gcttttataa
     1081 tacgattatt tgtaacaaaa tgaatattat ataattaaac actaccatat ttaggtagtg
     1141 tttaattatt agcaaaacaa aaaatattta ttctattctc ttaacttcaa ctaagttatg
     1201 ctgcacacct ttatataaat catatgcaac tcattagcta gacaaactac aagcatgtag
     1261 ttttatctgt taattatgta ctacctaaat aaagtagttt ataattagca agtatatata
     1321 tttaaaaatt taagattaat ttttttatga cttgtacaaa tttatctgat attctcttat
     1381 taagaactac ctaatttggg tagttcttat tttttacatt ttaagtagta tttaattgca
     1441 atttggtagt atttttttat tatcttattc ttagaacggt agtacttaat ataaatatag
     1501 gtagtatcta atttaagtat taatggtagt atctaaatta acaggtagta tgtaactact
     1561 ttaaagtaat ttttttcaga ttaacacagt agtatcttat taaataagtt aattttaatg
     1621 gtagtacata attattatat atatctgaca ttggtagtac ttattgtatt ttttagtagt
     1681 atataatcta ttgttttcta gcctaaagcc ttgtcttata agaataatat aatatatact
     1741 actgaaataa ggtagtatat attactagta atggtagtat gttttatatg cataaggtag
     1801 ttcttaattt attttttgtt ttgacactgg tagtacttaa ttatctttaa ttttaaaact
     1861 aaattttatt catacgtttt tctggtagta tttaattata aataatattt atttaaagta
     1921 gttcttaatg actttaaagg tagtacataa ttcattttat ttctgatttt aggtagtatt
     1981 taattaaaaa acagttttaa tgcgtttgca ttttttattt atctttgcta ttttcgaaaa
     2041 gagtaggtaa ttttacataa ataaaacaac gtgaaagtag aggatctaca atgactgatt
     2101 ttaaattttt taaggcggat agagtttaca acgaattatt ttatcaattt ccaaaagtct
     2161 ttattgtttc tgacgaatac aaaaaaatga aagattcaac taagattgcc tatatgcttt
     2221 taaaagcaag attagagatc gcaatcagca aacggcaaat cgatgaagaa ggtaatgttt
     2281 attttactta tacgacaaat gaactatgta gagtattaaa ctgccaaaaa caaaaagcga
     2341 tagcaatcaa aaaagagttg gaatcctttg gtttattatt acaaaagcag atgggattta
     2401 acaaacagtt agggaaaaat aatcctaata gactatatct agcagaatta aaagtctcag
     2461 aaaatgatat ctacttactc gaaaaatttg atagagagaa tagggaaaac gttgataaat
     2521 cagagggtat gaaaatcata cccaccctcg acgaaaaatc agacgctgaa tcccttgggg
     2581 ctcaagaggg tatgaaaatc ataccgtgcc aaaacgttga taaatcagag ggtatgaaaa
     2641 tcataccaga acttaataat aatatattag acactaatag acacaatata gacactgaaa
     2701 aagaccgcct acaagatcaa ttgttgttag acaattttga gacaattatg acaaacgaca
     2761 gcattgctac gtttgtccct gaacgagtat taaatttgat aaaaacattt tcttcaagtt
     2821 acagtgaagc tcaaaaaacc gtccagacta ttcataatgc aaagaaaaaa gctgaaatag
     2881 aaagtggtat ttcgatagtt tttgaagaac tcgatagtta ttatgtcaat gcagaacaag
     2941 aattatacac gacactgtta aaagcctatc aaaaattaaa aaccgaaaaa gtcgaaaata
     3001 tccagaacct gatttttgtc tatgtaaaaa attggtttat cgaaaaacca atagctgcta
     3061 aagtatcaag tgaaaaacgt ttgaattatg aaagctcccc aagcactatt acgaaagact
     3121 ggttagagtg aaactttact gacaaagtga ttgttgcttc atggagtaac attaaaatta
     3181 aaaatttttt attattctaa ttatattacg aatattacaa aataatagct attttaatag
     3241 aatttataag ttaaaatatt atgataaaaa tcacaaacgt agccttttac gtcataagtg
     3301 ttaaaagaaa taattaattt caaatataga aaagggaacg tatgtttgca tactcctttt
     3361 ttttgagtta taataatacg cgaagagaga taatttcatt atttaaacaa gctaaaaatc
     3421 ttgatattac ttcttttcag gcaatacgaa tattattcgc ttacattttt tgtataaatt
     3481 taattgtctg ctatgcttgt gatgaattga ttttcgttct gcacttttgg atgataaatt
     3541 tggacaattg aaaatacaaa aaaaagaaag gcggtatgaa ctcggaaggc tggtaacctt
     3601 cgtcagcgtt catacacggc attaagattt ggcccttaat gcgttaacct ttcagtgtta
     3661 cggtattacc cgcaatggat ttagtataac agatattcaa aagtgatacc actttttttg
     3721 gctgtgttaa ggttaaaaat acgtgatatt acgatgaatc tatgcctaag cacaatgtta
     3781 taaaaatgtc cgtgtggctc tttgccgtat gacgaacgct gaaattagag ggaacgcatg
     3841 tttggatgcg ttccctcttt tttgtttgtc atgaacgaaa atcaattctc tatttttgaa
     3901 aaataacaag aaaaacttgt taaaaatatt taaagaaatt gggtggttta ttttatgtca
     3961 tatacaggaa ttttgagtct caaagatatt tgtcactacg gtaaacggtg taccgctaca
     4021 gagaaaatca cgaagaaact atcaactggc caaagtaaaa ccgttgtgca gtgtaagaaa
     4081 tatataatcc agaaagacaa agtctcagag gaaatgattt attacattgg gaaacaaaag
     4141 caaataattt taaaagatcc tatcccctta aaagagctat atccaacaat caaacatgtt
     4201 tatgaccaaa acggtgtact gattggtcga agaaaaaatg gagtcttgcg ttgtaccgca
     4261 aaagggatgg ggcgtttgat cggctgaatt gatcattctc ataacttgta ttttatcgtt
     4321 tttcgcttgc ttgaaaatat tgtcgagact tctaaaggaa cttagagtca ctagaaaaat
     4381 aaggagtaga cttgatctat caacaattcc cttcggggag tgacggggta ggttttaacg
     4441 attggtaacg taaaaaattg gtcaatcgag taaatgcgct tgtttggata gtggtgaaat
     4501 gaatttgtgt aaataataag cgcagagtaa acaagaggga atttagaagt tagacaagtt
     4561 agaatagcgt ctagattaat catgagcagc tactaaggga tctagacttt gacgcaaact
     4621 catggaataa ggagtaggtc ttctcgtaat ggggaggacg cacaagaaat tgtgtcgtgt
     4681 gctgcagtac atgtagatac ttgcgaggac gttgattatt ggatcaatcg agcatttacc
     4741 gctgtctact agggtttctc gtttcggacg ccataaacga gtcgaaattt tttatgtatt
     4801 tttaagtaaa cgaaaaacga taaaatatga acaagtcctg aataaagtga aaaaattgat
     4861 ataaaacata gagaaaatga aatttacgta atggaggaat gacaaatgaa aaattatgat
     4921 ccgaatatac gattgggcac acatactatt aaggtttctt tccaacgttg ggattacaaa
     4981 ggatttgtga cgtttagaag aggcggaaat tgtaaaggat tagatgtttt agcattagac
     5041 gaggatgatt tatacgatca aacattgact gataatccaa ttggattcgg cttgctacct
     5101 gaagatgatg aaggtaatga atggtttaaa atgacgctta tgaatgataa tggagacgaa
     5161 ttatctgttg aagatacttg gtcatatttg agtgattata ttgtcagctt tgaaatcatt
     5221 gaatttgtag cggataaaga agaataaaaa ctggaggaat aaattttaca gataaaggct
     5281 tagaaggagt cacgatgatt aataaaaagg tagtattacc ttaggcattg agtaagga
//
LOCUS       DAFTHM010000138         5247 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFTHM010000138 DAFTHM010000000
VERSION     DAFTHM010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.139"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..1389
                     /gene="gadC"
                     /locus_tag="L7C88_002605"
     CDS             <1..1389
                     /gene="gadC"
                     /locus_tag="L7C88_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HBP9559391.1"
                     /translation="GGILWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAI
                     FFQWFQITVGFITMIYFILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTN
                     RTAKIAKAGFVIGIVIPSIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFV
                     SFILAYMGVEASASHINELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLS
                     LSAGVIQTFETLILHFNSHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGL
                     LPVFFRKTNKQDVPVPLIMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGY
                     LLFFLGYFVLVFKKKDLKRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAAS
                     EHRTYQIILLISFVVTVLLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEH
                     HVTKNDEHILKH"
     gene            1402..2802
                     /locus_tag="L7C88_002606"
     CDS             1402..2802
                     /locus_tag="L7C88_002606"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBP9559392.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(2967..4407)
                     /locus_tag="L7C88_002607"
                     /pseudo
     CDS             complement(2967..4407)
                     /locus_tag="L7C88_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            4800..5247
                     /locus_tag="L7C88_002608"
                     /pseudo
     CDS             4800..5247
                     /locus_tag="L7C88_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
BASE COUNT         1675 a          850 c         1001 g         1721 t
ORIGIN      
        1 ggaggtattt tatggtttct accagttgct ttatgtgctg cagaaatggc aacagttgaa
       61 ggatggaaag atggtgggat tttcagttgg gttagtcaaa ctttaggaga acgttttggt
      121 tttgcagcta tttttttcca atggtttcaa attacagtag gttttattac aatgatctac
      181 ttcatactag gagcgctgtc gtatgtaatt aattttccag agcttaatac agatccattt
      241 atcaagttta ttggtgtatt agtcattttc tgggtactga ctttttcaca gttgggcggg
      301 accaatcgta ccgctaaaat tgctaaagca ggatttgtca ttggaattgt tattccttcg
      361 atcattctct ttggtttagc agcagcctac tttatcggcg gtaatccgat tcaaatggct
      421 attaatgcga aagcttttat tcctgacttt tctcagcttt caactttagt agtatttgta
      481 tcttttatat tggcttatat gggcgtagaa gcttcagcat cacatattaa tgagctggaa
      541 aatccccaaa gaaactaccc attggcaatg tttttactag tgattttggc catcgcctta
      601 gatgcaatcg gcggtttctc agtagcagcg gttattccac aacatgactt gtctctcagt
      661 gctggtgtaa tccaaacatt tgaaacgctt attttacatt ttaacagtca tttacattgg
      721 ttggtaaaag tgattgctct catgattgcc tgtggcgtta tgggtgaagt tagttcttgg
      781 gtagttggtc catcacgagg gatgtttgca gctgctcagc gaggtctgtt accagttttc
      841 ttccggaaaa ctaataaaca agacgttcca gttccgttga ttatgataca aggaattatc
      901 gttactattt gggcagcagt cttaactttt ggtggaggag gcaacaattt atcattctta
      961 gtagcaatct ccttaactgt tgtcatttat ctcgtaggat atttactatt tttcctaggt
     1021 tactttgtat tagtttttaa gaaaaaagac ttaaaacgaa cttacaatgt accaggaaaa
     1081 actgttggca aaacgattat cggtggaatt ggttttattt tatcagtgtt cgcattgctt
     1141 atctcttttg taccaccagc ttcaattgca gctagtgagc accgaacata ccaaatcata
     1201 ctacttatta gctttgtagt gactgttctt ttacctttta tcatttatga agtacatgat
     1261 aaaagtgctc acacaactat tgaggaacct actcacgtga aagctgaaga cgttaatccc
     1321 gctgtttatc cagctgctag aggagagcac cacgttacaa aaaatgatga acatatttta
     1381 aaacattagg aggaattcat tatgttatac ggaaaagata atcaagaaga aaaaaactat
     1441 ttggaaccaa tttttggctc tgcaagtgag gatgttgact tgcctaaata taagttaaac
     1501 aaagaatcca ttgaaccacg aattgcttat caattagtac aagacgagat gttggatgaa
     1561 ggaaatgcgc gattaaactt agctactttt tgtcaaacgt atatggaacc tgaagcagtg
     1621 aaattgatga cccaaacgtt agaaaaaaat gcaattgata aatcagaata cccacgaaca
     1681 acggaaattg aaaaccgctg tgtaaatatg attgctgatt tatggcatgc tccaaataat
     1741 gaaaaattca tgggaacttc aacgatcggc tcttcagaag cctgcatgct gggtggtatg
     1801 gccatgaaat ttgcttggcg taaacgtgct gaaaaattag gtcttgatat tcaagcaaaa
     1861 aaacctaacc tggtgatctc ttctggttac caagtttgtt gggaaaaatt ctgtgtatat
     1921 tgggatgtgg aactgagaga agtcccaatg gatgaaaaac atatgtcaat taatctagat
     1981 actgtcatgg attatgtgga tgagtacaca attggtattg taggtattat gggtattact
     2041 tacactggtc gttatgatga tatcaagggt ctgaatgatt tagttgaagc tcacaataaa
     2101 caaactgact ataaagtata cattcatgtt gacgctgcat cgggtggctt ttatgcacca
     2161 tttactgaac ctgatctagt ttgggatttt caattgaaaa atgttatctc aattaattct
     2221 tcaggtcaca aatatggttt ggtatatcca ggtgtgggtt gggtcttatg gcgtgaccaa
     2281 caatacttac cagaagaatt agtatttaaa gttagttact taggtggaga aatgccaact
     2341 atggctatca acttctctca tagtgcagca caactaattg ggcaatacta caactttgta
     2401 cgctatggct ttgatggtta tcgtgatatt caccaaagaa ctcatgatgt tgctgtttat
     2461 ttagccaaag agatcgaaaa aactggtatt tttgaaatca ttaatgatgg atcagaattg
     2521 ccagttgtgt gctataagct gaaagaagat cccaatcgcg aatggacact atatgattta
     2581 tctgatcgtc tgttaatgaa gggatggcaa gtcccagcct acccattacc taaagacttg
     2641 gatcaattaa ttattcaacg cttagttgtt cgagcagact ttggaatgaa catggctggt
     2701 gattatgtac aagatatgaa ccaagcaatt gaagagttga ataaagctca tattgtttat
     2761 cataaaaaac aggatgtgaa aacgtacggc tttactcact aaaattcttc agagaaatat
     2821 aaaagaagtt aattaactaa taaaaggagt tgtgattacc acacagctcc ttaaatctat
     2881 ttgaataaat atatgatatt catttgttac actctcaatc ttagctgttg ttctattcat
     2941 cattactctt attgtaagta gttcagtcaa atttgcttgt tcaattgatc gataacagta
     3001 tgaattgttt gaaaagtaat cggatatata attgttttct cactacctaa gccttcttgg
     3061 tataaagaac tatcgcaaag tataatccgc tgagtacaaa agaaagtgtc gtctactatt
     3121 tctctaagtt gtttacaaat gatattacta atagaaaagt gttctcccaa aatgtcttct
     3181 aactgttgtc gatagtataa atacctaaag tctgacggag ctactatgaa cacttcaatt
     3241 ggagatttcc gtttatgctc atttaaaaga cttaaactaa tggttagttt acgaatagaa
     3301 ttctcattcc aacgcagaaa taaattgttt tgttttcgcc attgttcaag aatttcatga
     3361 acttctaagt acaaagcgcg ttgctcttca tttaacaagt aagtcttatc aggttgaaat
     3421 atctgaatat cagcccaaag tgagcggata aacgggagaa gtgctttatc aaaaagtatc
     3481 tgattttctt cagatatatt cagagataag ataagttttt gactgagctc aatcaccaaa
     3541 gggttatctg ctacatggtt ttgataaaca acgttcaagt ctttttgtaa caattcaaag
     3601 ttatcgcata gataatttct agagttgaat agaaagtaga tataaaggca ttcatcttcg
     3661 tcatgacata aagagaaaga aagttgctct aatcctttct gtattagctg aaacaaggga
     3721 gtatgtcggg caactctttt ttcttcctga ctaaaatata ttgggttagt cttagatctc
     3781 tgcaaaccga tagcgatacc taataaaata aattgttttt caactgtagg gtaacttctt
     3841 gaaaaaaaat gtttttctac ataatcaatc aattgttgac cgctttgaat aattgattta
     3901 tttagctgga tcaactctgt ccgatttgtc tcatagatta tcgttagtaa caaacttcga
     3961 taatcctttt caggaatttc aaaatggcca tcagcattta agtactgcat ttgtttaaaa
     4021 aaattaatca actcatttcg taagttgtaa actttgctta acgaaatgaa ggtagtatca
     4081 gctatattac tccaattgtg ttcccctgat aaataatgtc ctagtacatt gaaaaagtca
     4141 gagcgctgat agatgagttg agtgagtgcc aacctcgaaa acgaagagtc gaatgcgact
     4201 gtaaagctac ttctagattt ctccactgaa ataatttgct gatggagtat gtcggtaatg
     4261 cattccaagt cgttagtgac agacagtgag tgggcaaacg ttcaattgat ctgctatttc
     4321 gcgaatctga atggtccctt tttcgtgtaa ttgctcacaa atgtaaactt gacgaaaaat
     4381 acttttctcc agataggttt ccaacatagt actcctccta gtcattttat acataactat
     4441 tataactcta ccaatcggaa tagtcctgta atatattgaa tcaaaaatat aaattataaa
     4501 ataattagat ggggtatttg gtttaagtat cccttatata gtaataaatt tataggtgtg
     4561 attctcgaat taatacccga aaatgtgaga gaatttttat ggatttttta ggatacaaat
     4621 taattatttt tgcttttatc ctgattacca gtccagtact gtcggtatcc cattttgcag
     4681 caaaatcatg ttgataaagt gacaagaaga ctgatgagat atattatcca aattgagaag
     4741 ataattaatc ggattcttga gtatacccta ctttttaaga aagtagggta tacaagcgta
     4801 tgaataaaga cataactttc cctgtgatgg acgttcggct tgttccaatt accaaaatac
     4861 aggcgaacga ttataatccc aatcgagtag cgtctccgga aatgaactta ttggagcttt
     4921 ctatcattga agatggcttt actcaaccat tagtttgtta ttacaaggaa aaagaagaga
     4981 agtatatctt ggttgatgtg cttcataggt atcgtgttgc taaggaaaga ctcaacttaa
     5041 aagttgtacc ggtaacagtt attgataaac ccatataaga acgtatggct tcaacaattc
     5101 gacacaatcg tgcaagaggg acccatgaaa taagaggaat ggaaattgtc atccaaagat
     5161 tagtaaaaaa tggatggtca gacaagagaa tatccaaaga attaggcatg gacattgaag
     5221 aaatttttcg ctttaagcaa gtgtctg
//
LOCUS       DAFTHM010000139         5010 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFTHM010000139 DAFTHM010000000
VERSION     DAFTHM010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5010
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.140"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..164)
                     /locus_tag="L7C88_002609"
     CDS             complement(<1..164)
                     /locus_tag="L7C88_002609"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559393.1"
                     /translation="MDKKATMKRIIELTHSENWQEDKEIVAEVQKLGKSMWSEKTKRR
                     TPRKIAIWHG"
     gene            complement(167..328)
                     /locus_tag="L7C88_002610"
     CDS             complement(167..328)
                     /locus_tag="L7C88_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBP9559394.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            complement(343..702)
                     /locus_tag="L7C88_002611"
     CDS             complement(343..702)
                     /locus_tag="L7C88_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBP9559395.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCSQYRV
                     PLILAKKYRNTFKEERF"
     gene            complement(699..1550)
                     /locus_tag="L7C88_002612"
     CDS             complement(699..1550)
                     /locus_tag="L7C88_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBP9559396.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSYVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(1566..2396)
                     /locus_tag="L7C88_002613"
     CDS             complement(1566..2396)
                     /locus_tag="L7C88_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBP9559397.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKMQRNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            complement(2399..3085)
                     /locus_tag="L7C88_002614"
     CDS             complement(2399..3085)
                     /locus_tag="L7C88_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559398.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLSH
                     ETIKKLRIGG"
     gene            complement(3091..3762)
                     /locus_tag="L7C88_002615"
     CDS             complement(3091..3762)
                     /locus_tag="L7C88_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBP9559399.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            complement(3755..4096)
                     /locus_tag="L7C88_002616"
     CDS             complement(3755..4096)
                     /locus_tag="L7C88_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559400.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            complement(4274..4972)
                     /locus_tag="L7C88_002617"
     CDS             complement(4274..4972)
                     /locus_tag="L7C88_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBP9559401.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKNTMRISGQQEFEIKQKGNMKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
BASE COUNT         1255 a         1071 c          771 g         1913 t
ORIGIN      
        1 tcaccatgcc agattgcaat ttttctcggt gttctccgtt tggttttttc actccacatt
       61 gatttaccga gcttttggac ttctgcaact atttctttgt cttcttgcca attctcagaa
      121 tgtgtcagtt cgatgattcg tttcattgtc gctttcttat ccacgctcat tcctccaatc
      181 tacgaatttc ccttcttaag ttctctatgt gcaaatcgat tgcctttctc gccgtttcat
      241 tgaccatcac tgcctttgtc cgttccagat cgtcaatctc acgctgaagg cttcgaatac
      301 gcatttgaat cacttcttct gttgtcatga tggatcacct cgttaaaacc gttcttcctt
      361 gaacgtattc cgatatttct tcgctaagat cagtggtact cgatattgac tgcagaagag
      421 tttcgctttg attttgaaat cttttgtctg catcccttta acatctacga ctttgactag
      481 tttgccgttt ttataaaatg tgaagtcggg aatatactcg atcttgcgat acttctttcc
      541 gtctagttca aatttcggca tcagctcaaa tctttcctga agttttactt tccagccgtt
      601 cgcttcagct tgccacaagg ctagatcgta atactctgct tctgcgatag aatcaaactt
      661 gatacctcga tgaacagttt ttttattacg gtatttattc atgcgatact acctttcact
      721 ggttttatgc gcttgtctgc tgtttgttgg aatttcagcg cataaccttc tgaattctta
      781 aatatcctag aaacaattct ttcaccgtag gcttctctta gttcaggacc agataagttt
      841 gttgtgatga tcgttgcctt gttctgtctg gcttctaaga gcgtgtttaa cgtgttgttt
      901 gtaaattgcc tactatttga taccccgcta cctaattcag ctccaatatc gtcaaaaacc
      961 accaaatcag ttgttttgat atcggctata agcgatcctt caatttcttt tctcagttca
     1021 gcattgttat aagaaaactt tatttgctct aataactctt gatagcttat aaaaagtatt
     1081 ttcttgtcat aatttgagcg ctcaagtatt tcccaagctg tcgccattga taagtggctt
     1141 tttccgcttc ctgatttccc tgatagaatg aaatgtgcag gatggttcag taggacatca
     1201 tttacatagc ttttagctct ttctaaagca attttcgttt cttggtccac tacgtgataa
     1261 ttctccattt tgcatttaaa caaagtttta tctgttaata ccgaaccatt ttgaaaaaaa
     1321 ctcaatgctc gtgcttttaa gctgtcgtta tatatccgtt cggtctgtat atcctctttc
     1381 acacgtaacg ctttataacc acaactcata catgttggtt tacaacgttc tgaaccatcc
     1441 ttatttttag ctcgccaact atacaaaggt tcgctacatt ctggacattt tccgctttgc
     1501 actaatactc ttcttattag cttctccata gcatttgcta ggctttccat gtgatgcatc
     1561 tccttttaaa ttggcaagtc gtcatattca ctaggattgc tgtactgtag tttttgactt
     1621 tgctttttat gattcttctt gtctgctttg atttcgaatt tgagcttctc aaatttttct
     1681 ctcaatttct tagcacttct aatatttcca aaccaaaatt catttgtagg tagccaattg
     1741 atcacatact caatcgcttc tatagatgct ttatctcttt cttccatcaa cctgattgtg
     1801 tctgcccatt tttcgatatc tactttgttc atttcttttg gaaaatcttc agttaaattc
     1861 ctttgcattt ttttagcaag gcgtaagtgt tcgtcagaat acttaccttt cttttcttct
     1921 ttatctatat ctttatcttc ttctatatct ttatctgtac cgtcacgtga cgtcacgcta
     1981 acgtcatttt ccaatttgag acgttcctgt ctctttcttt ccctgtattt acggtttctt
     2041 tcagcatttt ttagccttac tttatccata ccctcgatat tttgatgttt ttcccaatta
     2101 ctgatggcaa ttagtccatc actgcttaga tcaatcatgt tgaaatttgc caatgtagtt
     2161 agcgctaagc gaaccgtatt tacgtttttg ccaaacaatg tagcaagcat ttcttcggta
     2221 taaggcatgt tcctctggat atatatcaga ccatcgtcgt tagtctttcc tgctaaaact
     2281 agtaatcgaa tccatataac gatgatggca tccgactcag gaacagcttg gattaaccgt
     2341 attttttcat cgtcaaacat agtagtttta agtttgatcc aacttatctc agccaaattt
     2401 atcctcctat ccttaacttt ttaatcgttt catgacttaa cttgattcct ttgatttgat
     2461 atttattttt aaaattgatc acacctattt tgtgcttctc cgtgtgatgg attctgcaga
     2521 gtgctgcaaa tgtgtactct gaatgatcaa cttcttttcg ctttcgtctt cctagcgctt
     2581 tgtcaaagtg atcgatgtca gctcctgttt tgccacagat gcaacaaact ctttttgtaa
     2641 tgcatttgta gaagtaatat tcttgattcg ctggtaaaat ctcatagcct tctttgaaag
     2701 gaatatgatg ttcaaagatg aaatctaaga tgatatttgc taagacatta gcatcactca
     2761 cagtcgtatt cgattcatct ttgaggctta ttttgcgccc tgtgacacct tcaaaacgga
     2821 agtagaagaa ttccttccag aagtccgttg gcatgcctgt atcgataaaa atatcgccta
     2881 tcagcgcata gatgaagttt cgttgctgta cggtgaaacg tctaggatca ataaaacgaa
     2941 tttcaatgac tcgatcacca tcgtagccgt catacatcgt ctttagtcga tcaatgttca
     3001 cttcctcatt gatggttgcg cttatgtctt ttcctttgaa ctttttcaga accgctgaat
     3061 atgaatcgat taatggttta aacactcata tcacttctta tctaattctt ttctcttagc
     3121 tgctattgct cgctccatca aggcacattg ctcatagctt aactgttcaa tagtttcaac
     3181 gttatcagct aagagcccta atttatctgt ctgctcatta acatattcga ttaaggtttt
     3241 ggtcatatct ttacccatct gctcattgaa agcttctaga atcgtctcta gcatgtttaa
     3301 tttctttgta tcgattctag gtggtgttgg aatatcttcc ccttgaaata catataatcc
     3361 cagtccgtgt agagccaatg ctttcacaaa gcatcgcttc aatgagttat tgatttgcat
     3421 tgcatttggt ttaacaactg gttggtttcg ataatctaaa acaggaaata attcggtttc
     3481 cgtgtgtcct ttaaccgtta ctgagacaga tacataagtc ccagtttcat ccataagaaa
     3541 aggtttatat tcctcaacaa gaaagtcttg atgagttcca gaaacaaccc tgtagtgttt
     3601 gtactcatta atagttaccg ttgcctgtgg atcattcttt ttcataatct cccacgcgtg
     3661 agcccaagat aaataatcaa aatttccttt tttcttgaga attttattta acttacgact
     3721 aaaaagtttt tcaaagttcg ttgtcccttt gatttcactc atcaaattct gcctccattt
     3781 cagcaatgta tttcttacct ggtccgtaat aagagatatc aatcaagtta tctctgtcgt
     3841 actcttctag cgcatcaatc aagccatctt cgatgacgta aatatattca ggtttattcg
     3901 aatgcttcga tagatggata agataaacat gatcccaaat agttacatgg ttgcctaaat
     3961 catcttgatc ccaagctagt tcttcattcg tcaaaagatt tcgtctgatt tttcgaccac
     4021 ttgtttcctc aattttcggc ttgccccaat caggatcaat caaatattga tctagagtgg
     4081 aaagttcttt ttccatatgc taaaatctcc ttatgatgtg ttttctttgt gactctttgc
     4141 ttgccggcgg agtcactttt ttatttgttg ccatgctttt tgcttgtcaa tatgttgttg
     4201 gcttaggatg attggtttat agtatttcca ccagcaatta gcaattgccg tccctattct
     4261 tagcgcttca gctctattca ttgtcatcac caaaaagtct ctgttgtctg ttcagttgat
     4321 caatttccat acggatcgca gtttctggca accacatttc aataaatgaa acagcatcat
     4381 cgaatctctt acgaggtaac tcgccatatc ttgggattga aaaggtacgt ttaaattcag
     4441 accaaaattt tgagaatact tttttgctga tttcttcata agctcggctt tcttttcccc
     4501 ctagaacttc cataactttc atatttcctt tttgcttaat ttcaaactct tgttgtccgc
     4561 taattcgcat agtattttta agcatggaaa catctttttt aacatctttc atttcttcta
     4621 gttggtagat catcatgtct tcaattgttt gaggaacagt attcttgcga ataacatctt
     4681 ccatttcgtt gaatgcttca atgtattttt gtttgaagta aatagctttc tttcctgtaa
     4741 aacccatagc caacaagaaa aaaccatctc tactaatgaa aaaaactcgt cgatttctgc
     4801 cgtatgaatc tggttcatta ccttctacaa acatctgtcc aaaattggac acatcttttt
     4861 ttagtgcatc aatatctctt aaaacatgtt gatgtttttt ctcaaagctt tctgccactt
     4921 gtaagctcgt agtcacagct tctttatttt tcaaaattac taattcttgc attttttctt
     4981 ctctcctttt ggtataattt aggtaaaaaa
//
LOCUS       DAFTHM010000140         4904 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFTHM010000140 DAFTHM010000000
VERSION     DAFTHM010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.141"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            9..668
                     /locus_tag="L7C88_002618"
     CDS             9..668
                     /locus_tag="L7C88_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBP9559402.1"
                     /translation="MKIVAIVPMKLNNKRLPQKNTKAFTNGKPLCYYILSTLLKVKQI
                     DKVYVYCSNPDIKEFIPEGVTFLKRSSSLDQDTTSITQVLAGFTKEVEADVYVMTHTT
                     APFISEKSIEKGLDAVLTGEYDSAFAAKKLQDFLWKDGEPFNYELDNIPRTQDLPPLY
                     EETSGFYIYNRNVMTELHRRIGKKPCIVEVGEIESVDIDEAEDFMIADAIYNHLILQG
                     S"
     gene            687..2270
                     /locus_tag="L7C88_002619"
     CDS             687..2270
                     /locus_tag="L7C88_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase catalytic domain-containing protein"
                     /protein_id="HBP9559403.1"
                     /translation="MNNVQILDCTLRDGGYCNNWEFGFDNTKKIISGLIESGIEIIEC
                     GFLTNKTVYNKNVTKYTTLEELAQIIPEKREGKLFVAMMNYGEYNIEDLPDYDGSSID
                     GIRIAFHKKNCNEALKLCREIKKKGYLVFVQAMVSLNYTDEEFLAVIKNVNQFKPYAF
                     YIVDSFGMMKGKDLTRLFYMIEHNLEKDIQIGFHSHNNMQLAYSNAQKLITVQTNRSL
                     IIDSSVYGMGRGAGNLNTELFVEYLNDNAGKKYQLKPLLYIIDEILNSFYQKSYWGYS
                     LPNYISAVHNAHPNYASYLSYKNTLTIEAMNEIFEMMDEEKKVSYDKQYIEDLYYKYM
                     ETGKIQEEYMEELRKFLSDKKILLIAPGKSSVDEVERIKEFVTKEEVVIISVNFEYSH
                     IDIDYVFLSNLRRFHELPKESRTKCIVTSNIQASDVYLRTSYKKLLSEREVVRDNAGL
                     MAIRFLADMNVDEIFLAGFDGYSHNEDENYGEQSMEIITKFALLDAMNVQMRDELSEL
                     AKKVKVTFLTDPRWVRIDK"
     gene            2405..2983
                     /locus_tag="L7C88_002620"
     CDS             2405..2983
                     /locus_tag="L7C88_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559404.1"
                     /translation="MISILCIVAYHANLRLNYNADGIIVHGSLTANQIFLNYIGIWGQ
                     LGVNCFIFISAYFLSEKRNIHFENVLGIVLECIFYSVLVYGILCACGIETFSLNSFVK
                     EILSFALGRYWFITSYLALYILSPYLNIMLNNLEKLQLQKISMLLFIGVCCYRMLFKT
                     SLFGDCAVLIALYVICYTLKKTIIIFLRDTES"
     gene            2929..3447
                     /locus_tag="L7C88_002621"
     CDS             2929..3447
                     /locus_tag="L7C88_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559405.1"
                     /translation="MLYTEKNDNNIFERHRIIGTIVCITVIPLLISIGILFKFIPNAM
                     VNQMVHIGSPLMVIASIFLFYVFKNFSFYSKYINKLARTSLGVYILHENHYFIDGMKS
                     RGLIWDGIFGLGKRFLDRDFWIWFIIAVVVVCIICMAIDVVREKFERQIFKIKSVKNL
                     CKLMNHVINIYP"
     gene            3455..4495
                     /locus_tag="L7C88_002622"
     CDS             3455..4495
                     /locus_tag="L7C88_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBP9559406.1"
                     /translation="MRRKEVKVISFGELLLRLAAPGYSKLFQRDSLETTFCGGEANVA
                     VSLAIFGYQSEFITKLPDSDVGYAAANALRYFGVNVDNIIFGEGRMGLYYLEKGAAQR
                     PSKVIYDRKFSAISLADSDEFKWKEILNDANWFHWTGINPALSENLFETSLDACQAAK
                     KRGITISCDLNYRSKLWTSEEAKEKMEQILPLVDICICNEEDAEKVLGIKAEHTNINS
                     GELNKDGYVQVAREIHKKFGCRYVATTLRRSYSASRNGWSAMLYEAEKDKAYFSTEYN
                     IQIVDRVGGGDSFSAGIIYALCENMSGQKAIEFATASSCLKHTIEGDFNRTTIEDVYN
                     LMNSGGNGRVLR"
     gene            4744..>4904
                     /locus_tag="L7C88_002623"
     CDS             4744..>4904
                     /locus_tag="L7C88_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9559407.1"
                     /translation="MTYTYLTTDELVIIESYLKINQSVAKTAHCLNRSSQTIHKVYLF
                     FKQRKSALE"
BASE COUNT         1803 a          566 c          961 g         1574 t
ORIGIN      
        1 gatgtcgtat gaaaatagtc gctatagtac caatgaagtt aaataacaaa agattgccac
       61 aaaaaaacac gaaagctttt accaatggaa aaccattgtg ttattatata ctttcaacac
      121 ttttaaaagt aaaacagatt gataaagtgt atgtctattg tagtaaccca gatattaaag
      181 aatttatacc agaaggtgta acatttttaa agagatctag ttccttagat caggatacaa
      241 cgagtattac acaggtatta gccggtttca caaaagaagt agaggctgat gtatatgtaa
      301 tgacacacac aacagcacca tttattagcg aaaaatctat tgaaaaagga ctagatgccg
      361 tgctgacagg agaatatgat tctgcatttg ctgcaaaaaa attgcaagat ttcttatgga
      421 aagacggtga accatttaat tatgaattgg acaatattcc tagaacacag gatttgccgc
      481 ctttatacga agaaactagt ggattttata tttataatcg caatgtgatg accgagttgc
      541 atagaagaat tgggaaaaaa ccttgcatag ttgaagtagg tgagattgag tcagttgata
      601 ttgatgaagc cgaggatttt atgattgctg atgcgattta taatcatctt attttacaag
      661 gtagttaaga cagggggaag gttaggatga acaatgtaca gattttagat tgcacactta
      721 gagatggggg ctattgtaac aattgggaat ttggatttga taatacaaaa aaaattattt
      781 ctggacttat agaatcagga attgagatta tagaatgtgg gtttctcaca aataaaacag
      841 tatacaataa aaatgttaca aaatatacga ccttagaaga attagcacag ataattcctg
      901 aaaaaagaga aggaaaatta tttgtagcaa tgatgaacta tggcgaatat aatatagagg
      961 atcttccaga ttatgatggt tcatctattg atggaattag gattgcgttt cataaaaaaa
     1021 attgcaatga agcgttgaaa ttatgtcgtg agataaagaa aaaaggctac ttagtttttg
     1081 ttcaagctat ggtatctctc aattatacag atgaagagtt tttagcagta ataaaaaatg
     1141 tgaatcagtt taaaccatac gctttttata ttgttgatag ttttggaatg atgaaaggaa
     1201 aagatttaac tcgtcttttt tacatgattg agcataatct agaaaaagat atacagatag
     1261 gttttcactc acataataac atgcagcttg catattctaa tgcacaaaaa cttataaccg
     1321 tacaaacaaa tcgaagcctg attattgatt cttcggtgta cggaatggga agaggagcag
     1381 gtaatcttaa cacagaacta tttgtagaat atttgaatga taatgcagga aaaaaatatc
     1441 aattaaaacc attattatat ataattgatg aaatactaaa tagtttctat cagaagagtt
     1501 attggggata ttcattacca aactatattt cagcagttca taatgctcat cctaattatg
     1561 caagctatct gtcatataag aatactttaa caattgaagc aatgaatgaa atattcgaaa
     1621 tgatggatga agaaaaaaag gtatcttatg ataaacaata tatagaagat ttatactaca
     1681 aatatatgga aactgggaaa atacaggagg aatatatgga agaactgaga aaatttctct
     1741 cagacaaaaa aattctactg attgcaccag gaaaaagttc tgtagatgag gtagaaagaa
     1801 taaaagagtt tgttaccaaa gaagaagtcg taataattag tgtaaatttt gaatattctc
     1861 atatagatat agattacgta tttttaagta atttaagacg ttttcatgaa ttaccgaaag
     1921 aaagcagaac taaatgtatt gttacatcaa atatacaagc atcggatgta tatttacgga
     1981 cgagttataa aaagttgtta tctgaaaggg aagttgtaag agacaatgca ggattaatgg
     2041 caattagatt tttagccgat atgaatgtgg atgaaatatt cttagctgga tttgatggat
     2101 attcacataa tgaagatgag aattatggtg agcaatccat ggaaattata acaaaatttg
     2161 cattattaga tgcaatgaac gtgcaaatga gagatgaatt gtcagaatta gctaaaaaag
     2221 taaaggtgac atttttaacg gatccacgtt gggttcgaat tgataagtag tagtaataat
     2281 gtttttaaaa ttttgataaa gagatagtga gagaataaaa atgggtaaag tcttaaataa
     2341 aaaagaagaa aaatatttaa gggacgatgg ggcgagatga aactctaatt ttgaactttt
     2401 aagaatcatt tctatattgt gtattgttgc ttaccatgct aatttgcgtt taaattataa
     2461 tgcagacgga attatagtac atggttcatt aactgctaac cagattttct tgaattatat
     2521 tggtatttgg ggtcagctag gagttaattg ttttatattt atttcggcat attttttaag
     2581 tgagaaaaga aacattcact ttgaaaatgt tttgggaatt gtattagaat gtatttttta
     2641 tagtgtatta gtttatggaa ttctttgtgc atgtggaata gaaacatttt cattgaacag
     2701 ctttgtaaaa gaaatattat catttgctct aggtagatat tggtttatta catcctattt
     2761 agcattgtat attctaagtc cgtatttaaa tatcatgctt aacaatctgg aaaaacttca
     2821 gttgcaaaaa ataagtatgt tattgtttat aggtgtatgc tgttatcgta tgttatttaa
     2881 aacatctttg tttggggatt gtgctgtttt aattgcacta tatgtcatat gttatacact
     2941 gaaaaaaacg ataataatat ttttgagaga cacagaatca taggaacaat tgtatgtata
     3001 acagttatac cacttctcat atccatagga atacttttca aatttatacc aaatgcaatg
     3061 gttaaccaga tggttcatat tggttctcca ttgatggtta tagcaagtat atttttattt
     3121 tatgtattta aaaatttttc attttacagt aagtatataa ataaacttgc gagaaccagt
     3181 ttaggggtat atattttaca tgaaaatcat tatttcattg atggtatgaa gtctagaggc
     3241 ttaatatggg atgggatatt tggattaggc aaaaggtttt tagataggga tttttggatt
     3301 tggtttataa ttgcagttgt agttgtgtgc ataatttgca tggctatcga tgttgtaaga
     3361 gaaaaatttg aaagacagat ttttaaaatt aagagtgtaa agaacctgtg taaacttatg
     3421 aatcatgtta taaatatata cccataatta ataaatgagg agaaaagaag tgaaagttat
     3481 atcattcgga gaattattat tgagacttgc agcacccggt tattcaaagt tatttcaaag
     3541 agatagtttg gagactacat tctgcggagg ggaagctaat gtagcggtat ccttagcaat
     3601 atttggatat caatcagaat ttataacaaa gcttccggat tcagatgttg gatatgcggc
     3661 agctaatgct ttgcgttatt ttggagtaaa tgttgataat attatatttg gagagggacg
     3721 catgggactg tattatttag aaaaaggagc agctcagaga ccatctaaag taatttatga
     3781 cagaaaattt tctgcaattt cgttagctga tagtgatgaa tttaagtgga aggagatcct
     3841 aaacgatgca aattggtttc attggacagg gataaatcca gcattgtctg agaatctctt
     3901 tgagacgtcc ttagatgcat gtcaggctgc caaaaaaaga ggtataacaa tttcttgtga
     3961 tttaaattat cgatccaagc tttggacatc agaggaagca aaagaaaaga tggaacagat
     4021 actaccattg gttgatattt gtatttgtaa tgaagaagat gcagaaaaag tgctaggaat
     4081 taaagctgag catacaaata ttaatagtgg agaattaaat aaagatggct atgtgcaggt
     4141 ggctagggag attcacaaga agtttggatg taggtatgta gctacaactc tgcgtagaag
     4201 ttattcggca agtagaaatg gttggagtgc aatgttatac gaagcagaaa aagataaagc
     4261 gtatttttcc acagaataca acatacaaat tgttgatcgc gttggtggtg gagacagctt
     4321 ttctgctggt ataatatatg cgttatgtga aaatatgtcc ggacaaaagg ctattgaatt
     4381 tgcgactgca tctagttgtt taaaacatac tatagaaggt gattttaatc gaactacaat
     4441 tgaggatgta tataatttaa tgaatagcgg tggaaatggt cgcgtgttgc gttagtcaac
     4501 atataaagat aaatcacagt aatttttatg gtgattatct gtcttagtag tgattagaat
     4561 aacgtgaaaa taaattgttg agcgtttata ctgttttgaa aaataaattt aacatattga
     4621 aaaatacaaa tatatacgta tattataaag cgccgattgt aaaattaagc tagacaacta
     4681 aaacagtcat ttgtgctaca ctcaaaatag ttccgaccaa agaattataa ggagtgagtg
     4741 caaataacct atacctatct tacaacggat gaacttgtaa taatagagtc ttatttgaaa
     4801 attaaccaat ctgttgctaa aactgcgcat tgcttgaatc gttcaagtca aacgatccat
     4861 aaagtatatc tgttcttcaa gcaaagaaaa tcagccttag aata
//
LOCUS       DAFTHM010000141         4890 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFTHM010000141 DAFTHM010000000
VERSION     DAFTHM010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.142"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(182..1144)
                     /locus_tag="L7C88_002624"
     CDS             complement(182..1144)
                     /locus_tag="L7C88_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9559408.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1146..2585)
                     /locus_tag="L7C88_002625"
     CDS             complement(1146..2585)
                     /locus_tag="L7C88_002625"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBP9559409.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2770..4716
                     /locus_tag="L7C88_002626"
     CDS             2770..4716
                     /locus_tag="L7C88_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBP9559410.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1577 a          821 c          795 g         1697 t
ORIGIN      
        1 acagttgtgt aaaaatatca ttttagagca tgaaaaaagg agtggatttc tccactccaa
       61 aaaagtctaa cttttggggg tcactacaag ttgacaactc ctttttgttt acaaatcaat
      121 tggatatcta caaattgtat tttctaacga attttataga cattaaaaaa ttaatttaac
      181 gttaaatact tcctccagaa agtattgaga ttggtaaaat ataatcctta tttgtctttt
      241 cgcctttaat ttttttcaga agaatatcaa caataagact tgcaatttca tcaattggtt
      301 gtcttattgt tgtcaattgt gggaaaaatt tctcaataaa agaggtacca tcgtatccaa
      361 taatttttaa atcttctggg atattaagtt taagttgatg agcaattttc atagtgagaa
      421 tggctgttaa atcatcagaa acaaaaatac catctggttt gtgatttata atagttgact
      481 ttatttccat ttcacgacgg atagtagaca gattattagg aattttgaaa atttttccat
      541 ttggattttg aaaagaaaaa cctagtgcac gtaattctgt gggagaatcc gtgttatcat
      601 ttcctgtaat cataatggta ttttgacaac catttttttg taaagtctta gctgcaagtt
      661 ttcccccttc aaagttatct gaagaaacaa tggaaacatt aggagctaaa tttctatcaa
      721 aagcaacaat aggtgctctc acacgctcat aatcagcaat tccaagatta tggcttgatg
      781 agattatgcc atcaacttgg ttggcttcaa gcatttcaat gtattctctc tctttagcag
      841 gatcattttg actattgcaa ataatcgttt tatatccatg tttaaataac tctatttcga
      901 gatactcaat gagttcagag taaaagatat tactaatatt aggaaaaata agaccaataa
      961 gctgaggtga ctttccttga agtccacgtg ctaaattatt tggtttataa ccaagagttt
     1021 tcatagcttc atgaactttt tgttttgttt tttctgataa atatccctta ttattaatga
     1081 cgcgtgaaac ggttgttggg ctaactccag ctaattcagc gacatcagtt aattttgcta
     1141 ccattttaat attttaattc aaagtatttt ccagtaggtt cgcctgattt gatttgaata
     1201 ccattttggt gattttcagg gaatacacga ctagtaaaca ctttttctcc tttattaata
     1261 aaaatctcaa tgattgagtt atctacaaaa atgttagcag ttgtttcttt agtatcaatt
     1321 gagcattcac gaatcgtacc aaagtcagtg gcatattgaa tgcctgcttt gctgcgatct
     1381 aaaataattt ttccttcttt ggtatctaca atcaagctaa gtccatttcc tttactatca
     1441 gagaaaagaa gtaactccga tttctgattt ggaggaaaag ttagttcaag ctcataagta
     1501 ttatttgttt ctgcttttgc tgtaaattgt tcagaactag cacgtaatga tgtaatagct
     1561 tctactggat attggtaaag tttaccatct tttattgaaa gttcttttac aagactcatt
     1621 gctccctgat aatcatactt atcagttgga taatcgatat caggtagtcc aatccaactg
     1681 acaatcagag cacgaccatc aggagtattg aatccttgag tcgcatacgc ttcaaatcca
     1741 taatcaagat tttgaatttc tgaagcgccc acaagtttta ctttttctat gtcaagcgat
     1801 tgacagatct taaaagtatt cggatagata ttcccataat ttagctcaga tttatccaac
     1861 ccttgaggac aataaatgag aacaggtttt ttgtctacaa atactagatt tggacactca
     1921 atcatgtatt ctgaaccagt gccgccaaaa tcaaggttgc caacttcctc ccatgtttcc
     1981 acgttattgt catccgcttt gtaaagtttg ataaagcctg atttttctaa attttgtgct
     2041 ccaacaatcg catacaattg tccttcataa ttaaacattt gtggatcacg aaaatgatca
     2101 gttacatcag caggtttatg aataagaaca ttctcacctt tcgtaatgtt gtagtcttta
     2161 tccatccatg ctccgatttg aagtgtatca cgttcccaat tttcatttcg aacgtttcct
     2221 gtatagagta agaatagatt cccctctatt tcatatgcag aaccggaata agcgccgtgg
     2281 ctatctcgtt ttgtgtctgg aagaagttct gctcctgtta catgaaaatg aactaaatca
     2341 tctgattcat tgtgtaccca ttctttcaac ccatgagcag ctccaaatgg ccaattttga
     2401 taaaaaagcg tatattttcc gttaaaaaaa gaaaaaccat taggatcgtt taacaatcct
     2461 gttttaggtt cgatatgata gctagcacgc caaggtgatc gttttacatt atccttaatt
     2521 ttatccatct catctttagt ccaatcagaa taagcacgat atcgtatttc tcgaggtaag
     2581 ttcatatttt actccttcaa tttatctttt tacaactagt atggtaaacg ttttccgttg
     2641 aaaaatcaat catttcattt aaaaaaataa actatatgac aaacgtttga catattttta
     2701 agatatgcta aaataaattt gcatttcagt gaaccgtttt cacgtaaaaa taaaaaagga
     2761 gtgattcgaa tgaattacag taaagtagct tccgacgtaa tacaagcggt cggaaaagat
     2821 aaccttattg cagctgcaca ctgcgctaca cgtcttcgtc tcgtactaaa agatgacacg
     2881 aaagtgaatc aaaaagcttt agacgaaaat ccagatgtga aaagcacatt taaaattaat
     2941 ggacaatatc aagtgattat cggtgcaggt gatgttaatt tcgtttatga cgaacttatc
     3001 aaaaaaactg gactttcgga aatttcaaca gatgatttaa aacaaattgc tagtaaagat
     3061 aaaaaattca accccattat ggcattaatt aaattattat cagatatttt tgttccaatt
     3121 atacctgccc ttgttgcagg tggtttatta atggcattac aaaacttttt aacagctgct
     3181 ggactttttg gaccaaaatc aattgaagaa atgtatcctg cgattgaagg tatttcctca
     3241 atgatccaac tgatgtccgc tgcaccattc atgttcttac caattttagt aggtatttca
     3301 gctgctaaac gttttggagc aaaccaattt cttggtgctg caattggtat gatcatgaca
     3361 acaccagatc ttggtggctc aactgaatat tggaatattt ttggttatca tgtttcacaa
     3421 acaaactatg cttatcaagt tattccagtt ttagcagctg tttggatatt atctatatta
     3481 gaaaaattct ttcataaaaa attgccatca tctattgact ttacattcac gccattatta
     3541 tcagtaatga ttactggatt tttgactttc acagttattg gccctgtaat gttattgttg
     3601 tctaatggaa ttacagacat tattgtttgg ctatataaca ctactggatt tattggaatg
     3661 ggtatttttg gaggaacata ttcacttata gtcatgactg gtttacatca atcatttcca
     3721 gctattgaaa ctcaattact ttcagcgtgg acaaatggta tcggacatgg agactttatc
     3781 tttgtagttg catctatggc aaacgttgct caaggtgctg caacatttgc catttggttc
     3841 ttaactaaaa attctaagac aaaaagtctt gcttcctctg cgggtgtctc agcacttctt
     3901 ggaattacag agcctgcctt gttcggagtt aacttaaaat accgctttcc attcttttgt
     3961 gctttaattg gttcaggaat tgctacagca gtagcaggat tacttaaagt agttgctgtt
     4021 tcacttggtt cagcaggttt cttgggattt ctttcaatta atgcaacatc tattccattt
     4081 tacgtattgt gtgaattgat tagctttgta gttgcttttg caattactta cttctacggt
     4141 aaaacaaaag ctgctggtat ctttaaagca gaagaaattg ctgaacaaac accagttaat
     4201 tcttcaaaag tagcaacaac agatccaata tctactgatg ttgaatcaac acaaacaaaa
     4261 gtttcatcag aaacaattgt tagtcccatt tctggtaaag tgattagtct ttcttcagta
     4321 aatgatccag tcttttcatc agaagctatg ggaaaaggga ttgccattaa accaaatgga
     4381 aacacggtcc attctccagt agatggtact attcaactca cgtttgaaac tggacatgct
     4441 tatggtatta aatcaaataa tggtgctgaa gttctaattc atattggtat tgatactgta
     4501 tcaatgggag gaaaaggatt tacacaaaaa gttactacta atcaaaaagt tagaaaaggc
     4561 gatattcttg gagcatttga ccgttcaatg attgagaaag aaggtcttga tgatacaaca
     4621 atgattattg tgaccaatac ttcggattat tcagaagtaa atatagtagc tgaaaataca
     4681 gtcactgagg gtactgattt acttgaaatc aaataaatat atttccctga gtaaagttgg
     4741 aattttcttt ccaaaatcaa ataatataga ttaatcaaat atttgagaat aacattttat
     4801 ttaatctttt catatatcaa ttgtatgaaa aattattaga attttaaaaa atgataaaaa
     4861 ttcaaaaaga aaaaatagta gttatttact
//
LOCUS       DAFTHM010000142         4720 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFTHM010000142 DAFTHM010000000
VERSION     DAFTHM010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.143"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..1097)
                     /locus_tag="L7C88_002627"
     CDS             complement(<1..1097)
                     /locus_tag="L7C88_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBP9559411.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVGGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENA"
     gene            complement(1227..2603)
                     /locus_tag="L7C88_002628"
     CDS             complement(1227..2603)
                     /locus_tag="L7C88_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9559412.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2603..3259)
                     /locus_tag="L7C88_002629"
     CDS             complement(2603..3259)
                     /locus_tag="L7C88_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBP9559413.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3269..4546)
                     /locus_tag="L7C88_002630"
     CDS             complement(3269..4546)
                     /locus_tag="L7C88_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBP9559414.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(4565..>4720)
                     /locus_tag="L7C88_002631"
     CDS             complement(4565..>4720)
                     /locus_tag="L7C88_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBP9559415.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
BASE COUNT         1477 a          858 c          566 g         1819 t
ORIGIN      
        1 gcattctcat tagagaacac tccctttttt gtgacttttc tgaagctaga gtgaatactt
       61 tcaactgcat tagtagtgta catgattttt ctaatggcgc tgccataatc aaagagttgt
      121 tcaacatgag aaaagtttcg tttgcataca tctactgcac cagaataatg agaccaccga
      181 ttttgaaaac tgtcgaaggc agcgtgtgca gcgtttaaag aagaagcact gtagaatttt
      241 ttcatgtctc gacagacttc cttataatcc ttacttggga ggtatcgtaa cgcatttcga
      301 acaagatgaa caatacagcg ctgcacaatg acagaaggaa aaattgcttt tgcgccttct
      361 ttgagaccgg aaacaccgtc catcgaaatg aaaaaaacat cttctacacc acctactttc
      421 agttcatcaa atacttgcat ccagcgattt ttagattctg tttgattgag ccataggcct
      481 aaaatctcct tgtttccttt aagatcatag ccaagaatgg tgtacacagc atattcttta
      541 gcttcatagt tttcgcgtaa agtgacgtac atacaatcaa cgaatagaaa tgcataacac
      601 ttggctaatg gccgagcttg ccattcttcc aattcaggaa ggacggcatc cgtgatatca
      661 gaaatcattt cgtgggaaat atcaaagccg taaatatctt caacggttgc ggcgatatcg
      721 cattgactca ttcctcgtgc atacatggaa agaaccttac cttcgatgtc ggagacatct
      781 cgttttctat taggaatcaa ctcaggttca aaagaagcct cccggtctct gggaacatca
      841 atgtttactt taccaaagct cgttttaagc gtcttattgc cataaccgtt tcgtcgattg
      901 tcatgtttct ttggctcttt agaatgggcg tcatacccta aatggttatt caattctcct
      961 tgaagcattt tttcaaataa gggaccaaac acatctttta aaacatcttg catatcctct
     1021 acagattcgg gttgataagt attcaaaatg gattcagcta acttctcagc atcaggattt
     1081 cttttctttc tagccatcgt gtaatcacct cttgatctta ttttagaaaa ataaaaaccg
     1141 tgaagcaacc acccgcctag gattgatggt tacttacacg gtttatatta cactctcatt
     1201 tttggtgcta aaaagcaccg aaaattttaa ttattgtcaa ttaataattc ttttggattc
     1261 cttcttaata tattgaatga agaaataatc aatgatacaa gaagtactaa actcataaat
     1321 ataactacat aaatcatgaa tttaggtaat acattgatat ctaaacttga taatgtcttg
     1381 ttaaatcctt cagcttctgc cccaccacct aattggctag atgcagattg tttagctatt
     1441 tgtttagcta tatcaccagt aaccttattc aatatattat tcccaagctt gtcagctgta
     1501 tattgagcta agaaatagga accaacgaat gcggggattg atataaatac catctcaatt
     1561 aggaattgac caaaaatttc taattttgat atacctaatg atagtaatac tgctatttct
     1621 ttctttctag cattcatcca taagaataat aataatgaaa ctacaactcc tgcaaatatt
     1681 aatgagccaa aaaataattt atttgaaatt gagtaaatac ctgatataga ttgttgtaat
     1741 gcagggtaat ttgatgaact tttaatcaaa ttatattctc tccaatttat atctaatttc
     1801 ccaagatctt ttattacact atcaagattc ttatcacctt ttacaaagaa tgttgcatct
     1861 tggtatacag ctgtatcttc ggtattacca taaactttag cagctgtatg aatatcagtg
     1921 attaatgtat tttcgtatag ttcttgtgct gcacttactc caccgctatt atgcccatcg
     1981 aatagacctt taatttctac ttctactgtt tcatctgcac ctttctcatt atcagcatca
     2041 aataaattag attttatttt tatcttatct ccaactttaa ggttattttt ttcagctaaa
     2101 tctttatgca ttaagatttt atttttatct tcattttcta aatgctttcc ttctactaat
     2161 ttatatgctt ctgatacaaa ttttgtttct tttgttgagt cgttaacccc agttaacata
     2221 actgttcttt taaaattctt tgctctttca ggtgattgat tcgcaagagt ctcttgagtt
     2281 tcaataatat cataatcaac taaatctgca acactgttta ttctttttac ataggagtct
     2341 atactatctg tttgagatat ctttttaata tcttcacctt ttacatttcc cccacctcta
     2401 ggtgttcctg gatttacttg tctatttatc tccatagaaa aactatttgt tatattagca
     2461 aatgtttctt ttgaagctct gtccgtagca tctttaatag ataaactaat gagacttaaa
     2521 gttgacatag ataaaataac taatatgata attaatgatt ttaaactttt tctagttaca
     2581 taagcaaatg cattttttat cattattcaa cctccaaatt cattttattt acttttttca
     2641 actttttacc acttagttct aaaatgatat ccgcagaatc tgctacttcc ttactatgtg
     2701 ttacaactat tacacattta tttctatctt tagctaatgt ctttaatata ttaattattt
     2761 ctccagcagt aacactgtct agattaccag taggctcatc agctagtatt attggagcat
     2821 ctgataccaa tgctctagca atagctactc tttgttgctg tccaccagat aatttcataa
     2881 catttctttt tatttgtttt ttatctaaac ctagttcaaa caagatactt tcatctgctg
     2941 atttatttac taatctaata ttttcaattg gtgataaata atctattaaa ttatagtttt
     3001 gaaatactaa agatatatta ttttttctat gattactata tcctttattt tgtatatctt
     3061 cattcttaaa caatattttt cctgtttgag gtttatcaag tccagcaagt aaggaaagaa
     3121 gtgtagattt tcctgttcct gactttccta ctatcgcata aaacttccca agttcaaatt
     3181 tttgatttac tcctgacaaa actttttctt tagaatttgc ataactatat gctacattct
     3241 ttatttctaa tatatccatt attttctcct aacttatttt tgataagatt tctttaggct
     3301 tcttgattaa cattaatgaa gaagcaaata caactgataa aacaataata cttattaata
     3361 ttaaataact ttgtccaagt gttgttatat ttgacataaa actactatta tttattaaac
     3421 ttccaccgga aatcattgaa tcctctgagt taatgaatcc atctacaatt acttttagta
     3481 atacatttcc taaaaataag gaagatatta tacttggtat cgatatgaat attaactcga
     3541 atataaattg cattataatt tgtatcttag atgttccaat agataagaat atacctattt
     3601 cataaattct ttcccttaac catagaatca agattaatga aagaacaacc atcccaccta
     3661 acataataga ataagtcatt acttttatta tatattttat tccactcact gactctaaag
     3721 actcttcaaa cgcattagaa tctttttcaa caaaatactt tgactcatca attttaagct
     3781 ctttcaattt gtttaaggct aagtctgtag attctgcact accagaatac attaaaattt
     3841 tatttgcaat ttcattattt tctgaattat ttaatatctc ttggcttgtt gaataatcta
     3901 caaacaccat attttcacta aaatcagaag ataatcctgt atatgtttcc tgttttttac
     3961 cagaaaagat ccctataatt ttaaatttat gactttttat ttttccactt ttttcaatat
     4021 ctagtaattc aagatcaact tcatcaccta attttagatt gttttgttta gcaaattctt
     4081 catgaacaat aattgaattc ttatcatttt cttctatatt tttaccttct ttaattgtaa
     4141 atactccact actaaataaa atatttcttt tagtattatt tgtagcttcg agtgaaacaa
     4201 cattcttaaa ttcgtcagat aaatcttctc tatttattct ttgttctccg ctaactactt
     4261 tagcatcttt tagttttgct aatccatcat attgaattat tttttcttca atttctttta
     4321 atttttcaat atctttaaat tgattaacat taaaatattt accatctttt tttgttattg
     4381 atattgaaga attagaactt tcatataaag ccttttctat ttcattgctt gatttcatta
     4441 ttgttaaaca agaatacaag caagaaagaa ctatagttaa tatgataaaa attattaaag
     4501 ttctattttt ctttcttgta atatatgcta tagcattttt tatcactttc ctaactactc
     4561 ctctctattt tcttactcca taactaattg catccactgg acaagcattt ttacatcgtc
     4621 cacatctgat acactccaga tgattgcaat tctcaactga atctttattc atttggcaaa
     4681 cttttttaca ttttccacaa ttaatacact tatccttatc
//
LOCUS       DAFTHM010000143         4711 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFTHM010000143 DAFTHM010000000
VERSION     DAFTHM010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.144"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            106..357
                     /locus_tag="L7C88_002632"
                     /pseudo
     CDS             106..357
                     /locus_tag="L7C88_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            450..1244
                     /locus_tag="L7C88_002633"
                     /note="aph(3')-IIIa"
     CDS             450..1244
                     /locus_tag="L7C88_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBP9559416.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            1654..1737
                     /locus_tag="L7C88_002634"
                     /pseudo
     CDS             1654..1737
                     /locus_tag="L7C88_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            1786..1869
                     /locus_tag="L7C88_002635"
     CDS             1786..1869
                     /locus_tag="L7C88_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HBP9559417.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            1994..2731
                     /gene="erm(B)"
                     /locus_tag="L7C88_002636"
     CDS             1994..2731
                     /gene="erm(B)"
                     /locus_tag="L7C88_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBP9559418.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(2994..3857)
                     /locus_tag="L7C88_002637"
     CDS             complement(2994..3857)
                     /locus_tag="L7C88_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HBP9559419.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAI
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQPPTP
                     PIPKTPKLPGI"
     gene            complement(3859..4131)
                     /locus_tag="L7C88_002638"
     CDS             complement(3859..4131)
                     /locus_tag="L7C88_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBP9559420.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            complement(4148..4357)
                     /locus_tag="L7C88_002639"
     CDS             complement(4148..4357)
                     /locus_tag="L7C88_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBP9559421.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(4455..>4711)
                     /locus_tag="L7C88_002640"
     CDS             complement(4455..>4711)
                     /locus_tag="L7C88_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="chromosome partitioning protein ParA"
                     /protein_id="HBP9559422.1"
                     /translation="IGFVPYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVS
                     TWSKNGITEHKGYDKKVLSMYKNVFFEMLERIIQLENEKE"
BASE COUNT         1446 a          796 c          865 g         1604 t
ORIGIN      
        1 ttcttgggag ttttgagact actatatgcg tttttttgtt gatttaccaa catgtttaga
       61 cattttcctc taggaaaaaa ttaactagca ccacgggtta tcttttatat agaagatatc
      121 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
      181 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
      241 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
      301 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
      361 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
      421 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
      481 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
      541 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
      601 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
      661 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
      721 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
      781 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
      841 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
      901 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
      961 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
     1021 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     1081 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     1141 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     1201 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     1261 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     1321 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag gggtcccgag
     1381 cgcctacgag gaatttgtat cgataagaaa tagatttaaa aatttcgctg ttattttgta
     1441 catttaactt gacggtgaca tctctctatt gtgagttatt agtggtacag ttttcaaccg
     1501 ttttaattat aaaaaagtgg tgcattttta aattggcaca aacaggtaac ggttattgca
     1561 ggtgtatttc ttatctatgg gtttaacatg gattttatca ttaaaatcat gagtattgtc
     1621 cgagagtgat tggtcttgcg tatggttaac cctaaagtta tggaaataag acttagaagc
     1681 aaacttaaga gtgtgttgat agtgcattat cttaaaattt tgtataatag gaattgaagt
     1741 taaattagat gctaaaaatt tgtaattaag aaggagggat tcgtcatgtt ggtattccaa
     1801 atgcgttatg tagataaaac atctactgtt ttgaaacaga ctaaaaacag tgattacgca
     1861 gataaataaa tacgttagat taattcctac cagtgactaa tcttatgact ttttaaacag
     1921 ataactaaaa ttacaaacaa atcgtttaac ttctgtattt gtttatagat gtaatcactt
     1981 caggagtgat aacatgaaca aaaatataaa atattctcaa aactttttaa cgagtgaaaa
     2041 agtactcaac caaataataa aacaattgaa tttaaaagaa accgataccg tttacgaaat
     2101 tggaacaggt aaagggcatt taacgacgaa actggctaaa ataagtaaac aggtaacgtc
     2161 tattgaatta gacagtcatc tattcaactt atcgtcagaa aaattaaaac tgaatactcg
     2221 tgtcacttta attcaccaag atattctaca gtttcaattc cctaacaaac agaggtataa
     2281 aattgttggg aatattcctt accatttaag cacacaaatt attaaaaaag tggtttttga
     2341 aagccgtgcg tctgacatct atctgattgt tgaagaagga ttctacaagc gtaccttgga
     2401 tattcaccga acactagggt tgctcttgca cactcaagtc tcgattcagc aattgcttaa
     2461 gctgccagcg gaatgctttc atcctaaacc aaaagtaaac agtgtcttaa taaaacttac
     2521 ccgccatacc acagatgttc cagataaata ttggaagcta tatacgtact ttgtttcaaa
     2581 atgggtcaat cgagaatatc gtcaactgtt tactaaaaat cagtttcatc aagcaatgaa
     2641 acacgccaaa gtaaacaatt taagtaccgt tacttatgag caagtattgt ctatttttaa
     2701 tagttatcta ttatttaacg ggaggaaata attctatgag tcgcttttgt aaatttggaa
     2761 agttacacgt tactaaaggg aatgtagata aattattagg tatagggcac ctctaataac
     2821 taccaattaa ttcacctcaa aatgaaatta gaaaaaaaca gcgaaatttt taaatctatt
     2881 tcttatcgat acaaattcct cgtaggcgct cgggacccca acatgaggaa atgtttttat
     2941 aaaaaaagag tagttaccgt tttttggtaa ctactctttt ccttttttaa ggtttaaata
     3001 cctggaagtt taggtgtttt gggtattggt ggtgtaggtg gctgcaagct ttccaatttt
     3061 tgttgaattg ctttaaattc aggtgtctct tggtgtttat ttagaaccat tttttgctct
     3121 attcgttcta aagtcggttg aatttctttc cctgatactt tacgattcaa ttctttttct
     3181 aaggtttctt ttggactaat agaaggtgtt tccaaacttg aatagagttt tactccttct
     3241 ctgttatata gccttatatc gctaaataag cccgttttat gaagggtttc taaattggtc
     3301 ggtaagtttt tgacaacaat atcatgcgct tgttttggtg ttgccctggc tgtcattgga
     3361 tcatctgcat acatggtttc atatcgttca attgttccta aatatgagtt gattttaggt
     3421 actgccatga catacatttt tgtttcataa cctttggctt gaagcattgt tgcggtttga
     3481 ataggaacgt ctgttgttcg tcctgtacct tcgatcacca aattataccc ttgatcgctc
     3541 aaacggctta tgatcgcttc tgtcatgcga ttagaataag gggtaacgtg ttttactacg
     3601 tctttttcat aaagtttcac tagttcatca aaattagggt gctgttgttt aaaggtatca
     3661 ttatcaatga caataacatt cccttgtgtt tcttcaaaaa ttgctgatcg caaactggtt
     3721 ttccctgacc ctggttgccc accaagtaaa aaagcggttg gcgattcaac cgcttttttt
     3781 ccttgaatca attcttctaa attatcattt aagcgattct caaattgttt gtcagtaaaa
     3841 ttgactatat ttgccatatt aagccacttt ctctttattc aaaacttgtt ttgagtaacg
     3901 attcattgac cgccaatact catgaacggc ttgtaattct tctaaagaat aatcaaaaag
     3961 atttacacgt tttgcaagct ttaattggtt taataaattg acttccaata attgagagtc
     4021 atttttattt aattcatggt tcaaaacata gtttaatact cgattataaa cgcttgccga
     4081 taattcgtta atgatctcta tttcaaatgt tttttcatac gtaactgcca tttcattttc
     4141 actcctttta aagtttgtca ggtaaatatt tccgtatata ttcttctaag gcttgatcca
     4201 taacttcttt tacgtttccg ccattctttg ctgtttcgat ttttatgata tggtgcaagt
     4261 cagcacgaac acgaaccgtc ttatctccca ttatatcttt ttttgcactg attggtgtat
     4321 catttcgttt tgctttttgt gcgcctaaat ttcccacaat cactcacttc tttctatttc
     4381 ttcttactct tattttatca tcaacaatca caaatcacaa gtgatttgtg attaatcact
     4441 tgtgatttgt gattctattc tttttcgttt tctaattgaa taattcgctc aagcatttca
     4501 aaaaatacgt tcttatacat ggataaaact tttttgtcat agcctttatg ctctgtaatg
     4561 ccgtttttag accaggtact tactttatta cttcgcttga taatattttg gaaaaccaag
     4621 ttatcttctt tatgttgctt atacagttct tccaggtttg attttatcgt tgcgctgtcc
     4681 gtatcaacta aataaggaac aaaaccgatc a
//
LOCUS       DAFTHM010000144         4682 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFTHM010000144 DAFTHM010000000
VERSION     DAFTHM010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.145"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..522
                     /locus_tag="L7C88_002641"
     CDS             <1..522
                     /locus_tag="L7C88_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559423.1"
                     /translation="SKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYGIDETDIFAK
                     VNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLLISPISTIS
                     FSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLSEEKILLPEN
                     WAELRKLVEYGII"
     gene            509..1930
                     /locus_tag="L7C88_002642"
     CDS             509..1930
                     /locus_tag="L7C88_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBP9559424.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            1943..2950
                     /locus_tag="L7C88_002643"
     CDS             1943..2950
                     /locus_tag="L7C88_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBP9559425.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            2962..3966
                     /gene="neuB"
                     /locus_tag="L7C88_002644"
     CDS             2962..3966
                     /gene="neuB"
                     /locus_tag="L7C88_002644"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBP9559426.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            3963..>4682
                     /gene="neuC"
                     /locus_tag="L7C88_002645"
     CDS             3963..>4682
                     /gene="neuC"
                     /locus_tag="L7C88_002645"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBP9559427.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICIL"
BASE COUNT         1658 a          598 c          831 g         1595 t
ORIGIN      
        1 agtaaattga tgaaaaacat acaatcaatc tttgggatag aagaagtttt tgtcggagat
       61 aaatgtatct tttttgatca acctttatta tctgatggtt atggcataga tgaaacagat
      121 attttcgcta aagtaaatag tatattttct ggaaaaaaag aaactttaat taagcttcat
      181 cctagagcaa ggacaaatcg ttatggtgaa aaaaacatat tgaattccag tttaccgttt
      241 gaagtcttgc tacttgaaaa tgacttctct tcaacacttt tgattagtcc tatatctaca
      301 atttcttttt caccatctat gatgtttgaa aagacgatca actctattat gttggctaaa
      361 ttaattttaa atgaatatac agcattatct gaagataaaa aagaaacatt gacaaatatt
      421 gttcttttct gtgaacatta taaccgtcta tcagaagaaa aaattttact cccagaaaac
      481 tgggcagaat taagaaagtt ggtagagtat gggattattt aacacacttt ccaagtcaaa
      541 attagttaag tccagtttct ggtatactat agggaatttt tttattaagg gaatttcatt
      601 cataactatt cctatttttg taaatattac tactcaagca gaatatggtt tgattaataa
      661 tttcacttca tttgtatcaa ttttttcgat tcttgttggg ctaagcctaa attcggcaat
      721 taataatgca agttttgact ataaagatga cataaatgaa tttatgtcat cggtactttc
      781 tctagctaca ctttcgttaa ttgtgttctt attaataggg aacatatatt ttttgttttc
      841 aaatgctttt tttgatatga accaacttgt atttaatttg atgttattac aaagttttgc
      901 tagttttgta attagttata tccagtctta ttttacgatt aactttaacc attttaaata
      961 tttgatttta tcttttatat ctactttttt gaatattgca atctctgtag ctttgatgca
     1021 gacattatat tttgatgata aatatgttgg cagagtagtc ggcggaacac tgtcatttgt
     1081 gttgataggt ttagtaattt atttaagaat aatgataaag ggtgctcatt tttttgataa
     1141 aaaacagtgg agatacgctt taaaaatctc tttgccgcta atcccacatt ccttagcaaa
     1201 tatagtttta gcacaattcg atagaattat gattaattct tatttaggtc ctgctgcggg
     1261 gggaatatat tcctacatta gtaacatagg tattattcta agcgtaatat ggatgtctac
     1321 taataacgcc tgggttccat ggttctatgg tgagatgagt aaaaataatg aaaaaaaagt
     1381 gaagaaagtt agtaactatt atttagtagt ctttactttg attacgatga ttgtaatggt
     1441 agtttcgatt gatttagcaa aatttatggc tccgaaagac tattattctg ggttatcttt
     1501 agtggttccg ataaccttag gctatttctt tcagttttta tatagtttac cagttaatgc
     1561 tgaattttat gagaaaaaaa catcgtttat tgcgattggt acagtagcaa gtgctatagt
     1621 taatatacta ttaaacatga ttttcatacc taggttagga ataattgctg ctggatacac
     1681 aaccgtattt acgtattttt tactttttat ttttcattat aatatcgcta aaaaaattac
     1741 gaataaacaa ttatttgaca caaaaaaaat atgtatcata ataatttttg tatcaatttt
     1801 ttctttgata cttcatattt taatcaatca aatgttgatt cgttacgttt tgacatcatt
     1861 attgataatt agtttagtta tatatttttt aaagattaag aatcgaatta tagatgacta
     1921 taattcatag gaggagatat aagtgtttaa aggaaaaaca atattagtaa ctggcggaac
     1981 tggttccatt ggaagtgaaa ttgttcgtca gcttttaaaa tatgaaccaa aagctatcag
     2041 aatttatagt agaggtgaag aaaaacaatt ttatatgcaa caagagctct caaatcacac
     2101 taatttgaga tttttaattg gtgatatcag agactctcaa aggattgatt atgcatgtcg
     2161 tgatgtggat attatttttc atgctgccgc aatgaaacac gttccagcaa gtgaatataa
     2221 tcctatggaa gctgtaaaaa caaatgtgat gggaactcaa aatgtaatag atgcagcgat
     2281 caaaaataat gtaaaacatt ttgtaggtat cagtacagat aaagtagtga gtcctactaa
     2341 caccatgggt gcgacaaagt tattgagtga aaaattaata atagctgcca atcagtataa
     2401 aggaaaaaca gaaacaatat tttcttgtgt aaggtttgga aatgtcatgg ggtcaagtgg
     2461 atctgttatt cctcttttta gtaaacaaat aaaaaacaat aaagatatta ctttgacaga
     2521 tgttgatatg acacgattta tgatgtcaat accggatgct gcaagattag ttctgtctgc
     2581 tgctatgaat tcaaaatttg gagaaacata tgtcttaaaa atgccggcaa tcaatatttt
     2641 aactttagct caatcattaa taaaaatata taatgataca catgatgaaa aatatagagg
     2701 tgaaataaaa gttgtaggta tcaggccagg agaaaaatta tatgaagagc taatgactac
     2761 agacgaaatt gaacgctcat atgaaaatga taaaatgtat atcattccac cacactatca
     2821 tgctactgac gaactgtaca aagattatga aaaaattaaa atcactgcat actcttcaga
     2881 tgcaacagaa ttaatgagtg gacaggaatt tattagaatc gcaaaagaga ataatgtcgt
     2941 gacttggtaa ggagttttat gatgaaatca gaagtatatg taattgcaga aattggtgta
     3001 aaccataatg gaagtctaga tttagcttta gaaagtattg ataaagctaa agaatgtgga
     3061 gctaacgcgg ttaaatttca aacatttaaa acgaataagc tagtttccaa aaaggctcca
     3121 atggcaaaat atcagaagga taatcttaaa gaggacagtt ctcaatttga aatgctaaaa
     3181 aaattagaat tatctcaatc tgattttatt agaataaaag attattgtat acaaaataaa
     3241 attgattttt tgtctactcc ttttgatgaa gaaagtgcag actttctaaa acaaattggt
     3301 gtacaaggat ttaaaattgg ctcaggagat ttaacaaatt taccttttct tagaaaaata
     3361 gatatgtatg ggttgccagt tttattatct acaggtatgg ctgatattca tgaggtcagt
     3421 gaggctgtag attgtttcat agatagtcca gttactattt tacattgtac ttcaaattat
     3481 ccggctagtt ctgaagatat taatttattg gcgattaaca cattaaaaga aatgttcggg
     3541 atacccgttg ggtactccga tcattcattg ggatatgatg ttggtatttg tgctgttgcg
     3601 atgggtgcta aggtaattga gaaacatttt accttggata aggaactacc tggtccagat
     3661 cataaagctt ctttagatcc tcaggaattt gcagattttg taaagcatat tagaaacact
     3721 gaaatatttt taggtgatgg tgttaagcga gcaatgcctt ctgaacttag tacaaaagaa
     3781 gtatcaagaa aaagcctagt ggtcactgag aatttaaatg tgggagatat tcttacagag
     3841 aaatctctta caataaaacg tcctggaaat ggaatagctc ctaagttttt atatcaatat
     3901 attggcaaaa aagttaaaag accaataagt gcagatagtg ttctgcttga ggaagatgtt
     3961 gaatgaaaaa aatacttata gtaagtggaa cacgagctga ttatggaata tataaacctg
     4021 ttgctgagaa tttactacaa gataattggg atgtatcatt tgttgtttct ggaatgcatt
     4081 tatcccataa atatggattt actaaagaat tgatcttagc tgacggattt agaattagtg
     4141 gagaagttca aagtttgttt ttagagaaca ataagggaaa catggctcgg tctgtggcat
     4201 tagagataaa tggtttcaca aatatatttg aacaaactag ccctgatttt gtattattac
     4261 taggggatag aggagaaatg ttggcagctg cgatagcttg tttgtatctt ggaatcaaaa
     4321 cagcacatat tcacggaggc gaagtgtctg gtactgtaga tgaatcaata agacatgcca
     4381 taacgaaaat agcatctgtt cattttgctg ctacggaaaa aagcaaagag cgtttaataa
     4441 aaatggggga agattcttgg agagtttttc ccgtcggagc tcctagaata gatactattt
     4501 taaataatag attacctagt tttagagata taaaagaaaa atatcatcta aaatttgaaa
     4561 agaaaaaata cgttttgcaa gtatttcatc cagttgtaac cgaactagaa aatatagaaa
     4621 aacaaatttt agctttgatc aattcaatgg aacaacaatc tcaaccaatt atttgcattt
     4681 ta
//
LOCUS       DAFTHM010000145         4612 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFTHM010000145 DAFTHM010000000
VERSION     DAFTHM010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4612
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.146"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(85..339)
                     /locus_tag="L7C88_002646"
     CDS             complement(85..339)
                     /locus_tag="L7C88_002646"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBP9559428.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRPQRSNKPIMDRLQLTRQKN"
     gene            complement(450..704)
                     /locus_tag="L7C88_002647"
     CDS             complement(450..704)
                     /locus_tag="L7C88_002647"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559429.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
     gene            complement(897..1172)
                     /locus_tag="L7C88_002648"
     CDS             complement(897..1172)
                     /locus_tag="L7C88_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBP9559430.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(1144..2097)
                     /locus_tag="L7C88_002649"
     CDS             complement(1144..2097)
                     /locus_tag="L7C88_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBP9559431.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            2709..4202
                     /locus_tag="L7C88_002650"
     CDS             2709..4202
                     /locus_tag="L7C88_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBP9559432.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            4337..>4612
                     /locus_tag="L7C88_002651"
     CDS             4337..>4612
                     /locus_tag="L7C88_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBP9559433.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRK"
BASE COUNT         1494 a          774 c          802 g         1542 t
ORIGIN      
        1 tgcttgaatt cttgtgaaaa agttcttcgt gttctcttag acataaaaat tcctcctggt
       61 atgttttctt ctagtctaca caccttaatt tttctgtcta gttaattgta gcctatccat
      121 gatcggttta ttagaccttt gaggtctata ttttttaact acaatcgacc ttaaatttaa
      181 ttgtttcatt agcttttgga catgtttaag agatactgaa atcccttctt ttaataaaac
      241 ttgatggatc tttgtggcac catagcgttg tttattcgta aaaaaaattg ttgaaatctt
      301 ctttttcaac ttattatttc tgatttctgt agctgtcaac ggtttattct tataaaaata
      361 atagacactt ctagggattt ctaataaccg acacaacaaa gaaacagtgt aatccttaca
      421 ccatttttca ataaattgaa caagcgaatt taggttttcc gagagaatat ggctgcggct
      481 ttttttaaga tttcaagttc ctcatttaaa cgagcatttt cttttctcag ttcagctact
      541 tcttttccag tcagtcctgt ggactgatca ggtaaatata aattcttcca tttgtaaatc
      601 gttgcttcag ataagccata ttctttcgct aaccctcgaa cagaacgtcc agtttgattc
      661 agttcaacaa tcatttgttt aaaattttct tcatatcggg tcataaaaat tcatcctctc
      721 gtagataagt ttaatttatt cttgtctcta cgaaaagctg tctaagattt gatactaaca
      781 ccaaatgttg tataccccca aacaatacac atattttgaa ggattaggat taataaagct
      841 aaaaatatag taagtatact aaatatattt actatatcta gtatacttac tatattttaa
      901 tcttttgatc gtctattata tataatccgt tcctcgtcgt ttaaagtatc aacataggcg
      961 tccattgcaa gtttgactat ttcatacata ggaatatctt ttgcataact aagatcccga
     1021 atggttttta gtacgggagg atctacttga actggttttc tttctttcgc agtgtacttt
     1081 cgttccccta actcgacatt aatatcatct ttaattgaaa tatcttcagc accaattttc
     1141 ttcttatctt tgttcgttgg taataatgcc atttagttta atctcctttc caagaggtag
     1201 gatatgattg gccattgagt cagcatattt aggtgtataa tcaaatcctt caatatcacc
     1261 atgttgttca tagtattcaa ttctttcttc taattctgta aagatgtctg caaaaatagc
     1321 ccaccatctt cgatctacat aatcatttaa ttggatacca ttctcaccat acatttctaa
     1381 ccgatccgag cctttaacaa tgcttttaaa aatgtttgat tcaccatact tatcaattgt
     1441 tttttgatag tttgcgtgtt gagaggaacg tcgcactgag aaaagaacag gcaaaattcc
     1501 aatgatttga agatgagact cttcaaaatt cgtgacaatc ggaactaaaa ctttattaat
     1561 aaaatcttct gttccttcca ttgcgtaccg ttttaattct tgcattgcaa taatataatc
     1621 tgcagcagtt aagaatgcac gaaccacatt atctgttgat ggtgggcagt cgataaagat
     1681 ataatcgaaa ttttttctca attcttctaa aggtttaatg aaggccaatg atctcttacg
     1741 acgatcagga tatttttcgg acaagtattc attaagttct tcagatccag gagagccagc
     1801 cataatatat aaatgtggac ttacttgagt aatacctgaa acccagtccc cttttttgat
     1861 tgctgcagac atggatcgat caaagctagt aatttgatac gttgatccaa tgttggaagt
     1921 agtatttctt tgttggtcat aatcaattag caacacgtct ttttcaaaaa gttgactaga
     1981 aacaatcgct aataaatcat tgtctgtagt cttaccaatg ccgccttttc tacctgtaag
     2041 cattacaact tttcctagtt tatctgatgt tttaaatgca gtccgtaagt tttccatagt
     2101 tccctccaat ttcctatact aaatatattt agtatacttc atatacttaa tatattcgat
     2161 atatctaata tactccaaat tgataagaat tcagacttta taaggaatat agtggatata
     2221 ctaaatatat ttgctatatt cagtatatca gatatattca aaatgtcaaa atatatttgt
     2281 gcgttttgcg ttgacaattt agagtgaaaa gaggtaaact taattctata gaaaccacag
     2341 ataattcact atttacaaag tagcaaaagc agtggtactc tttaaacaga aaaattacat
     2401 aaaaaaaaga gacggaaata attgatttta gcagaatcaa ttatttctga atcacatggt
     2461 taggacatgt gttcacgctc gtctcaagaa tatgtaagta gctaccaact acttatatta
     2521 aaagttgatc ggataccttt tccgattgcc tttattctac caaaaaaagg cgagcaactc
     2581 aacagaagaa cgtttattta gtgtacttaa attaaatatt cttaaacact gaagagagaa
     2641 cacatactat ggctgagatt aaagctaaac tgtgttctct ttttgtttga gaaaggacgt
     2701 tacaatcgat gttgagcgaa atttattcag ctattcttaa aaacggctta cgtacataca
     2761 aatatcgaaa cagcaccatg aaacctgcag gtcatattga ttccagtagg agtggtgcta
     2821 tctttgcgta ccgtagcaag caattaatga atgttgggcg tggtatggtc attacttcgg
     2881 aagaagctat tttagagaac gaaaagaaac taacgcattg gacacctaat acctatcgct
     2941 ttggtactta tgcggatgat tatcgaacag tggttaaagg tcattctgag aaaaacttaa
     3001 gtcaaatcaa cacatttgta gttgatatcg attcaaaaga gaaccatcaa ggcgaaatta
     3061 ttttagcctg tttagatcaa gtgggctaca tgccaacgct aattttagaa tcagatcatg
     3121 gttatcaagt ttattttgta ctaaagacac caggctatgt cacaaagaaa agcaatttca
     3181 aggtgatcga tgtagcaaaa aaaatttcaa aaacaattcg tctacagttg gctgaaaaat
     3241 tgtccggagt ggatctagga tgtaaccact tcggaattgc tcgattccca caagaaaata
     3301 atattgtttt taaagaaatg aactatcagt attcttttgc tgactggatt caatggtcga
     3361 tgaagcttga atcagatcaa aaaacaaaag aagatcgaga acgaaaacta attgtctttc
     3421 ctgagaaaaa agaaattcgt caagtagatg aaccgtggtt cgatatgtta cttcataaag
     3481 caaacatcgt cggcggagaa ggacgtcttg gtcgaaataa tgtgattttc acgctttctt
     3541 tagcttatta ctcttcaggt tatgcattgg atacttgcga atacaatatg ttcacattca
     3601 acgaacggtt acaggaaccg ctatctgaag cagaattagt aaagattgta cgtagtgctt
     3661 attctggtaa ttatcaagca gcaagcagag aattcattat tgaattgtgc cagcaatggg
     3721 tttcaccaac cttaaaaaat aatgatctgt tcattcaacg acgtggctgg tggaaattta
     3781 aaaagccacg agatcaaaga aaatatagtc ataaaaatga atggaaagaa gatctattgg
     3841 cttatctaag cgaaaaaagt cttgctagtg agccttattt gaacctgtca aaaaaagaat
     3901 tggcttcaca actaacgatg cccaagcgaa cacttgataa gatcttaaat gagttacgag
     3961 aggagaataa agtcttctac aaggtaacac gaggaagaaa tggcggaatg atcattgctt
     4021 cagtcaaaac gttgttcgcg agggttattc aactaagtaa agaaaagaga ctagattatt
     4081 caacaaggat cacagaggta tttggactca acgagagctt agtagaagag acatttagac
     4141 aattatcaac ccccttgaac cctcttaaag aagtgaatct ttttgaagta gatacaggtt
     4201 gaaaaataaa aggtgcaaat tgccttatac aatatatcta tgatacttct gtaggtgttg
     4261 ctccctttgc ctagctacgt gtaggtggta tacttataac tgcgtatgca gtcttatgta
     4321 tcatggagga agttgtatgt cgttaaaaaa ttatgtctat tcacatcctg ttaatgtgtt
     4381 tatcattggt cgtttgggat tatctgtgga agtgttctgt gagctttatg gttttaagca
     4441 ggggactttg tcttcttggg ttaccaggga aaaaacagtt gcttctttgc cgattgagtt
     4501 tcttcatggg ttgtccttag cttctgggga gactatggat caggtatatg attgtttgtg
     4561 tgtgttagag caggagtata ttgagtataa aatagctaac gagttaagaa aa
//
LOCUS       DAFTHM010000146         4606 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFTHM010000146 DAFTHM010000000
VERSION     DAFTHM010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.147"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            89..2734
                     /gene="polA"
                     /locus_tag="L7C88_002652"
     CDS             89..2734
                     /gene="polA"
                     /locus_tag="L7C88_002652"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBP9559434.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            2779..3615
                     /gene="mutM"
                     /locus_tag="L7C88_002653"
     CDS             2779..3615
                     /gene="mutM"
                     /locus_tag="L7C88_002653"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBP9559435.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            3579..4208
                     /locus_tag="L7C88_002654"
     CDS             3579..4208
                     /locus_tag="L7C88_002654"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBP9559436.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            4260..4592
                     /locus_tag="L7C88_002655"
     CDS             4260..4592
                     /locus_tag="L7C88_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBP9559437.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
BASE COUNT         1617 a          830 c         1022 g         1137 t
ORIGIN      
        1 tatttggtat ggtcccgctt tttcttttcg cattccgcag gattctttgt tagaatgaat
       61 aagaacttta cagtaaggag ttaagaagat gacaaaaaat aaattattac tcgttgatgg
      121 gaacagtgtg gcttttcgcg cattctttgc gcttcacaat tctcttgaac gtttcaaaaa
      181 tagaaacggt cttcatacaa atgcaatcta tgcattcaat acgatgtttg aaaatgttat
      241 gcaaaaagag caaccgactc atgttctggt tgcgttcgat gcaggaaaaa cgacttttcg
      301 gacagaaatg tatgcggagt acaaaggtgg aagatccaaa acacctggcg aattcaaaga
      361 acaaatgcca tatatacgtg atttgttgac aggactaggg gtacagtatt acgaattgcc
      421 caattatgaa gcagatgata ttatcggtac tttggcagaa aaagtagaca aagatcaatt
      481 tgatgtcgtc gtgctttcag gtgatcggga tttgactcaa ttagctagta aagaagtaaa
      541 agtggatatc actgtaaaag gtgtcagcga tatcgaaagc tatacaccag aacatgtagc
      601 ggaaaaatat gatgggttga cgccaaaaca gattattgac atgaagggac tagccggaga
      661 tgcctctgac aatatccccg gtgtgactaa aatcggtgaa aaaacagcta tcaagctatt
      721 gaaacaatat ggctcagtcg aaggaattta tgaacatatc gatgaaatga agcaaagcaa
      781 aatgaaagaa aatctgataa atgacaaaga gcaggctttc ttatcgaaaa aattggcgac
      841 catcaatact tcagcgcctg tggatgtctc tatcgactca ttgaagtatg aagggaaaaa
      901 tctcgataaa ctcgttccgt tttataaaga aatggatttc aatcagttcc tttctaaatt
      961 gaatatcgta gaagaagaag taaaaatgga tgatattttg tttgaagtcg ttcatgaatt
     1021 caaagaggaa atgtttacta cggatatggc gttgtacgtg gaaatgatgg gcgacaatta
     1081 tcatacagag gaaatcgtcg gagtagcgtg ggggacagaa aagaaaattt atgtcacgaa
     1141 cgatctatct gtattcgaaa accgagcgtt ccattcttgg atcactgatc cgactcggct
     1201 gaaaaaagta tatgatgcga aacgaactta tgttgcttta aaccgctata ctggaaaaac
     1261 gaaaggaatc gattttgatg tcttgctagg tgcatacctt ctcgatacga atgaaaaaag
     1321 cacagatatc gaaggaatag ctgctcatta cggatacaac gatatccaat cagatgaagc
     1381 tgtatacggc aaaggggcga aaaaaggttt accagaagaa gaggaactct tttttgctca
     1441 tttagcgcga aaagtagctg caatcaatgc gttgacacca aaattgagcc aagaactggc
     1501 agataaaaac caagaagatc ttttccggaa aatggaactg ccattgtcta tcattttggc
     1561 agagatggaa ataagcggga tcaaagtaga tgcgactcgc ttacaagaaa tgaagggcga
     1621 gttctctgct cgcttaagag agatcgaaca aaaaatctac gaagaagccg gcgaagaatt
     1681 caatttgaat tcaccaaagc aattaggagt gatcttattt gaaaaaatgg gattacccgt
     1741 tatcaaaaaa acaaaaactg gatattccac agccgtagat gtactggaac agcttcgtga
     1801 acaagcacca atcgtagagg atatcctcac ctatcgtcaa attgcaaaaa ttcaatctac
     1861 ctatgtcgag ggactgctga aagtgatcca atcagatgga aaagtgcata cccgttatgt
     1921 ccagacattg acccaaacag gacgattaag ctctgttgat cctaatttgc agaacatccc
     1981 gattcgatta gatgaaggga gaaagatacg tcaggcattt gttcctagag aaaaagactg
     2041 gctgatttat tcttctgact attcacaaat cgagttacgc gtacttgcgc atatctcaaa
     2101 tgatgaacat ttgaaagctg ccttcctaga aggtcaagat atccatgcca gcacagcgat
     2161 gcgtgtattt ggaatcgaaa aggcagagga tgtcacacca aatatgcgta ggcaggcaaa
     2221 agcagtgaat tttggtatcg tgtatggcat ctctgattac ggactttcac aaaatctagg
     2281 aatcagccga aaagcagcac agcaatacat cgatacgtac tttgaaaaat acccaggtgt
     2341 caaagaatat atggaaagaa tcgtacgcga agcaaaagac caaggctacg tcgaaacgct
     2401 gtatcaccgc cgtcgatatc tgccagacat caattcaaga aattacaata tccgttcttt
     2461 tgcggaacga acagctatca atacaccaat ccaaggaagt gctgctgata ttttgaaaat
     2521 cgcgatgatc gaattggata aacgattaaa agaaacaggt cttcaagcta cgatgctgtt
     2581 acaagttcat gatgaacttg tcttcgaggt accggaaaaa gaacttgaat cattagataa
     2641 attggtgaag gaagttatgg aacaagctgt ttctcttcat gtaccactga tcactgacag
     2701 cagttgggga aaaacgtggt acgaagcaaa ataaacattg tttaagacag agcaatataa
     2761 tgaaggtgaa aagaaaaaat gccagaatta ccagaagtag aaaccgttcg taaaggattg
     2821 gaacggttag tagtaggaaa aacgattcaa aaagttcagg tcttgtggcc caagatcatc
     2881 gagcaaccag agacacccat ctttgaggct tctcttgttg gcgaaaccat ccaatccatt
     2941 ggacgtagag ggaagttttt aatttttcat ctcgatcatt gtgaactgat ctcacacttg
     3001 cgaatggaag gaaaatatca atttacgaaa gaaaatacac caatcgataa acatacgcat
     3061 gtacttttct tttttgagga tggaagccaa cttcgctaca acgatgtacg aaaatttggt
     3121 cgtatgacaa tcgtcgaaaa aggagcaagt gcaacttacc gaggaatcat gaaattggga
     3181 cctgagcctt tgccagatag cttcttatta gcagatttcg caaatggact gaaaaagtcc
     3241 cacaaagcaa tcaagccatt gctgctagac caacgtctag tgactggtct aggtaatatt
     3301 tatgtagatg aagcattatg ggaagcgaag atccatccag aacaaccggc gaacacactg
     3361 cgccccaaag aggtagaaca attacgtcta tcgatcattg atgttttgga tcgtgcaata
     3421 gaagccggag gtaccacgat tcgcagttat ttgaatgcat taggagaatc aggcggattt
     3481 caagtagcac tgcatgtcta tcagcaaact ggcaaaccat gtatacgttg tggaacgccg
     3541 atcgtgaaaa caaaagtggc acaaaggggg acgcactatt gtccgaattg tcaaaggcta
     3601 aaaatcgcaa agtaggattt gttttaggtt tgacgggtgg aatagctacc ggtaaaagta
     3661 cggcagccaa agtctttcag tctcatggat ttcctttgat cgatggcgat gtgattgcca
     3721 gagaaactgt tgagcctgga acgcttgctc tgaggaaaat tgtatcagtg tttggccaag
     3781 aggtattgca gcctgatggg caactagatc gagggaaact tgggatgatt gtttttccat
     3841 caaaggaaaa acggcaaaaa cttgatcagc tattagatcc gtttatccga aaagcgataa
     3901 aagatcaaat cgcctctcta agttccaatc atcctttagt aattgtagat atcccattgc
     3961 tctacgaagg tcattatgac cactatatgg atgcagtagc tgtcgtttat actacgccag
     4021 aaactcagct tcagcgtttg atgaaacgta atcaactgac gctagaacaa gcgcagcaga
     4081 gaattagtag tcaacttcca atcgaagaaa aaaagcagcg tgcggatatt ttgttcgaca
     4141 acaatggaac aaaagaaaaa cttgtgggac aaatcgaaaa ttggcttttt gctaatcgct
     4201 ttctttgagt atctgtgtca attttgctat cctgagtata tagaaagtga gggatagcga
     4261 tgggatcatt aaaaaatcaa aaggataaag tcgtaggtaa cgcaaaagaa aaaatcggcg
     4321 agatgctcaa taaagaaaat ctaatcgatg aaggtcgtac gcaatcagaa acagcagaag
     4381 aaaaagaaaa gcagtaccaa gcaagaatcg atgaaataga agaccagcag gcagaagaag
     4441 aagcgaagcg gcaagatttg actcaagaac gaaaaaatcc gacacctgat cgtagtaaaa
     4501 caccgctccc agaaagtgac cacatttccg atgagcaaaa aatcgaggaa cagcgaatga
     4561 aacactatac aggaatcgaa gagaagttat aaaatagtaa aaaatc
//
LOCUS       DAFTHM010000147         4499 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFTHM010000147 DAFTHM010000000
VERSION     DAFTHM010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.148"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..199)
                     /locus_tag="L7C88_002656"
     CDS             complement(<1..199)
                     /locus_tag="L7C88_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBP9559438.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDF"
     gene            893..1279
                     /locus_tag="L7C88_002657"
     CDS             893..1279
                     /locus_tag="L7C88_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBP9559439.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            1373..1564
                     /locus_tag="L7C88_002658"
     CDS             1373..1564
                     /locus_tag="L7C88_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9559440.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            2078..2410
                     /locus_tag="L7C88_002659"
     CDS             2078..2410
                     /locus_tag="L7C88_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559441.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            2706..2861
                     /locus_tag="L7C88_002660"
     CDS             2706..2861
                     /locus_tag="L7C88_002660"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBP9559442.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            3137..4477
                     /locus_tag="L7C88_002661"
                     /pseudo
     CDS             3137..4477
                     /locus_tag="L7C88_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT         1576 a          806 c          749 g         1368 t
ORIGIN      
        1 taaaatcacc agtaaagaaa tggaaatctt tagttttttt aatattatca gttagtaact
       61 ttttataatc ataaaaaaaa taagtagttc tatctgagcg atactctttt ataatactga
      121 attcggaatt aaaaaccacg ataggtaact ttaaacaaac atgaagagac tttaataaga
      181 cttctttatc tgaaaacact tttgtttctc tctttccttt ctacatcatt aaatagtatt
      241 ttatacgtta tctaaaatac tattcctctg tcaaaataag ctaacttact tcattataaa
      301 atatccactt atcgctttca tgtatattcc accgtaaaaa gtacatttta tcaccgagaa
      361 ctcatcattt ttcatcatga tgaatactat ttacatatat ctagttcaaa gacaataatt
      421 attatgatcc gttattatct aagcactata cagataatag gaatttttcg tttctaaata
      481 ttccaatttg ggaatccaat aaaaattttc gttcaaatac gtgtctattc gaactctttt
      541 ctagttgtta attatgaagg gggaagaaat aaaaaataca atctatacac gaataagaat
      601 attatccaaa aggaggtttt agaaaagatt tattatacgt aaaaagctca agacattttc
      661 ttagccataa ggacatgttt gatatttaag aagatatatg aattttcttt tctaagtata
      721 aagataacta tccattatca actaaaaaaa catttttgaa aataaacatc agcagtccta
      781 tcaatgcatg tgagcttata gaagttattc gcagcgcagc ataattgcat tagcttcttt
      841 tcgtgttttt tgcctctttt ccctttaaat cttaatggag gaggtgtgca atatgtcaga
      901 taacgacgaa cgcgtaaatg cccagttgat tcgattcttt gaaaaggtca ttttgaacac
      961 cgctaatact tattataaaa aacaagaaga aattcaaaaa catgaacaac ttgatcaact
     1021 cccaccatat ttgtttacta aagatactat aaaatttaaa caaccgatta atgttttaaa
     1081 tgtgactctc cttgttgaag atataaaatt agcaaaaatc cttcctttgt tgaaagaacc
     1141 tgaacaaatt tttcttatcg aaaaatttat ctttgataaa actgataaag aaattggaaa
     1201 ggttctgggg attacaagac agggtgcgac aaatttaaaa catcgacttt acaaaaaaat
     1261 tcaaaaaatg ctggtttaat atctgcataa taactaattt tgtatgcttc tttgctcgtt
     1321 ctcctccttc ccaaagaaat agattataag tccatgggaa gaaggtagat ttatgaattc
     1381 tttaaaagaa gatttcattt tagcaaaggc tggaaatgaa gaagctgttg aggcaattct
     1441 caaaagattt agctctttga ttcataagca atcctggaga actggaaaat atgatcaaga
     1501 ttgttatcaa gaatgtatgc ttgcaatata tctagctatc tcgaaattcg aaattaaaga
     1561 ataactcaac taagggagtc tgtgacataa gtaaaaagat agtttcaaat ttcgaacaat
     1621 aaatttgaaa ctatcttctt tataattata aagtatcgat tttacagcgt tctataatga
     1681 ttcatagaat ctaaaacgaa tgattttaat tatcaacgtt ttttaattcg tttttagctt
     1741 aaaaataact tttgtcacag tctcactcct aaaattactt tatttacgta tgaagtgggc
     1801 aggaggtcga atccagaact gggctatggt acttcaacga ggacttctcc tctagaattg
     1861 aaaagcatgc gatttacctt ccgtaacgac ggtagattta ttcaactatg tgtccaatca
     1921 aaatttgtct gatttcaaaa atagtcaaga gaattttggt tgttaaaaac tcttatctat
     1981 caacttccac agtttagttg acaaaccctg atactaagtt gggctatgat acacttttct
     2041 tgactatcag ttacgttacc ggaaggaatg aactctattg agaaaaacat atgatcgtaa
     2101 atttaaacta aagatttcac aggatatcct tgagaaaaaa gtaactacca agaaaattgc
     2161 tgaagaatac aatatctctc gtccaacaat ttcccgatgg gtttcagaat atcgtcgata
     2221 cgggaaaaat gcttttgctg gacaaggaaa aagattacct gataaagcag atttctacat
     2281 tcttgaacag gaaaataaac gactaaaaga ggaagacgag tgttctacga acacaaagat
     2341 cgatacggat ctccagggat cactcaaaaa ctttacgatg aaggaatcga aatcaataaa
     2401 cgtgttgtag ctgttcttat gcgtgaaatg aatttatgca caagaggatt tcatcgacgc
     2461 aaatcttctc atggtagaga aaaaacaatc aaagaaatgg taaaaaaatg ttgaatcgat
     2521 aatttgaaca gaaccaaatt gatgctgttt gggtgatgga tattacttac attccatgta
     2581 atgacggtcg cctctatttg tccacctata ttgacttagc aactcgtatt ctacgttact
     2641 atatggtaga ttcacacatg aaaaaagaga ttgtcgtccg tccattacaa atttattaag
     2701 gagaattgcc tacggtaatt cattccgata gaggtagcca gcatcggtct tttatttatc
     2761 aagagctgtt gaacgaccac cacatcacac attcagtgag ccaaactggg actcctgttg
     2821 acaatgcagt aattgaagcg tttcatcgat caatcaaatg agaattaatc gactccaaca
     2881 aatataaaag taaaatagag atgaaggtgt taatccaaga ttatttagaa gactactacc
     2941 caaacaaaag aatccataca aaatttatga tgactccttg acaatttgaa gcgaagaaaa
     3001 taagggatct ataatatcta gtgttggtga cgccttctgt tgccaatact ttttcttttt
     3061 tctaataaac gcaaacagac accttaaaat cctttagaat aaagtcgacg aaaaccattc
     3121 aaaggagtgt ttcaagatgt cctattcaga gtttaccaaa gagttactag atattctaga
     3181 cctaaatctt atctttcatg aagatgcctt tcgcaaagag cgaatcaatg acgaaacatg
     3241 ttttgttttt gatggcacat tgacctatca accggaggaa tgctttcatc gccactatca
     3301 aaatgaacaa acgatcatta aatagggctg gaaaaaagta tccatcttat tgaatgatgt
     3361 cagtaactac aagaccattc tgcggattaa caaacagcgc ttcaaatgta aacactgtgg
     3421 aaagactttt ttagcagaag attcagttag tgatcgtcgc tgctccattg ctcgcagagt
     3481 caaacaagcc attcttgagc tattaagcga acctctttct atgtctttga tcgcacgtat
     3541 gaagcacatt tctccgacca ctgtcattcg aatacttcgc agccttcggc ctaaaaccat
     3601 ttctttgagc cagctgttac cagaagtggt gtgtttcgat gaattcaaat cagtgaaaaa
     3661 tgtctcggga gccatgagct ttgtcatgat ggacggcaag acccatcaac tgattgatat
     3721 tgtggaaaat cggcaactca atcctttacg cgactatttc ttgcgctacc ctataaaagt
     3781 ccgtgaacaa gtgcgtctag tggtttcaga tttctataca ccctatcgca cattggtgaa
     3841 agagtgtttt ccgaatgccc gaatcgtcgc cgatcgcttt catattagcc aacacattgg
     3901 tcgggctttt accaaccacc gaattcaagt aatgaagacc tttaaaaaag gggatcgtcg
     3961 gtcgaagcac ttaaagaaat actggaaact acttcaaaag aatgcgtggg aattgaaagg
     4021 tcagcatcgc tactggcgtc cgtcatttcg agatcatctg acagaagcag agatagtcga
     4081 tcggctatta tcttatgatg attccttaaa gcgaggctac gaagtctacc aggattttct
     4141 ttccgttatc agaagacaag atgttcctga attcgtcgcg ctcctaaaag aagactacaa
     4201 ggagttgcca gagcactacc aaccagtgtt cacgaccttc aagaaatacc aaacagaaat
     4261 caaacgagcg ttgcgcgttc cctattccaa cggccctata gaatgtttga ataaccatat
     4321 caaagtacta aaacgaattg cctatggcta tagaaacttt caaaactacc gagaacgaat
     4381 ctttttatat cgaggaaaat attttaagaa aactaagaat actacccaac tgactaaagc
     4441 cagaacaaca acacggctag acaagatagc tgtctagccg tgtgagtatc tcgattatt
//
LOCUS       DAFTHM010000148         4475 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFTHM010000148 DAFTHM010000000
VERSION     DAFTHM010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.149"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            323..1054
                     /locus_tag="L7C88_002662"
     CDS             323..1054
                     /locus_tag="L7C88_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBP9559443.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            1199..3226
                     /locus_tag="L7C88_002663"
     CDS             1199..3226
                     /locus_tag="L7C88_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBP9559444.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            3334..4431
                     /locus_tag="L7C88_002664"
     CDS             3334..4431
                     /locus_tag="L7C88_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBP9559445.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT         1574 a          717 c          923 g         1261 t
ORIGIN      
        1 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
       61 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
      121 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
      181 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
      241 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
      301 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
      361 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
      421 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
      481 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
      541 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
      601 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
      661 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
      721 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
      781 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
      841 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
      901 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
      961 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
     1021 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
     1081 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
     1141 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
     1201 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
     1261 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
     1321 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
     1381 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
     1441 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
     1501 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
     1561 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
     1621 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
     1681 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
     1741 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
     1801 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
     1861 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
     1921 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
     1981 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
     2041 gcaaagaagt cttacttatg atttggaagg tgtcggtcac tcttctcgga ttatacctga
     2101 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
     2161 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
     2221 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
     2281 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
     2341 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
     2401 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
     2461 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
     2521 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
     2581 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
     2641 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
     2701 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
     2761 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
     2821 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
     2881 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
     2941 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
     3001 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
     3061 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
     3121 tacagctcat cgtggaatca gaatagatat tcctgtagaa aaccaaagaa tcggaacctt
     3181 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
     3241 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
     3301 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
     3361 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
     3421 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
     3481 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
     3541 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
     3601 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
     3661 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
     3721 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
     3781 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
     3841 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
     3901 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
     3961 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
     4021 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
     4081 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
     4141 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
     4201 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
     4261 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
     4321 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
     4381 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
     4441 aacaaatagt aaatttttat tattgtagga tggtt
//
LOCUS       DAFTHM010000149         4428 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFTHM010000149 DAFTHM010000000
VERSION     DAFTHM010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.150"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(543..2048)
                     /locus_tag="L7C88_002665"
     CDS             complement(543..2048)
                     /locus_tag="L7C88_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBP9559446.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="L7C88_002666"
     CDS             complement(2045..2731)
                     /locus_tag="L7C88_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9559447.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="L7C88_002667"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="L7C88_002667"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBP9559448.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1237 a          919 c          729 g         1543 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaac
//
LOCUS       DAFTHM010000150         4425 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFTHM010000150 DAFTHM010000000
VERSION     DAFTHM010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.151"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            690..1658
                     /locus_tag="L7C88_002668"
     CDS             690..1658
                     /locus_tag="L7C88_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBP9559449.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="L7C88_002669"
     CDS             1669..2484
                     /locus_tag="L7C88_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HBP9559450.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="L7C88_002670"
     CDS             2552..3262
                     /locus_tag="L7C88_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBP9559451.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4425
                     /locus_tag="L7C88_002671"
     CDS             3298..>4425
                     /locus_tag="L7C88_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBP9559452.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1490 a          661 c          921 g         1353 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaat
//
LOCUS       DAFTHM010000151         4358 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFTHM010000151 DAFTHM010000000
VERSION     DAFTHM010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.152"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="L7C88_002672"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="L7C88_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBP9559453.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="L7C88_002673"
     CDS             complement(2944..3378)
                     /locus_tag="L7C88_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559454.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..>4358)
                     /locus_tag="L7C88_002674"
     CDS             complement(3395..>4358)
                     /locus_tag="L7C88_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBP9559455.1"
                     /translation="FGPFRANNIDKVFFKLKMNNLNVAMADRERLYNSLQNLTLYSLG
                     DIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKTIEQIKIDNLLSQNYDPEIYLFLY
                     ENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKNYSIIVFEKLAQTSITLG
                     MDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEIGKTKIEHLSPLISSVVQ
                     FIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNYISKRKISTAKIMLKSNH
                     TISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFNNIS"
BASE COUNT         1340 a          815 c          601 g         1602 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaat
//
LOCUS       DAFTHM010000152         4348 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFTHM010000152 DAFTHM010000000
VERSION     DAFTHM010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.153"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(387..1853)
                     /locus_tag="L7C88_002675"
     CDS             complement(387..1853)
                     /locus_tag="L7C88_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBP9559456.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKKITEPETVVQP"
     gene            complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="L7C88_002676"
     CDS             complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="L7C88_002676"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBP9559457.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
BASE COUNT         1309 a          927 c          697 g         1415 t
ORIGIN      
        1 aataaatggt gttcaatcag ctgaccttca gcattagctc aaaaagcggc aaaatatgag
       61 gagctatttt tccgtttgtt tctctaatac tcaggtcaaa tcgctgattt tacaacctct
      121 tccttaaacg gtgttccaaa gcttgcatct gcggtaataa gcccagccaa acgaaaaata
      181 tgaggggcta tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac
      241 ctctgattca cggtgttcca gaagtagctt cttcgaaaaa caagccgaaa cttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttgt aacaagtatt tctattttaa ggctgaacca ctgtttctgg ttcagtgatt
      421 tttttgtttt tgtctcgacg agcaattgct ggcaagatca tacctaataa gatcaagacg
      481 attggtgtga tgatattcgt aaataattgg aaccaccatg ctttaggatc agcagtataa
      541 tctacttttg gcaccattcc taggatacat gcaaacgcag tgaaggcaaa gcaccaagca
      601 ccaaagataa aaccgatttt tggattttta acaaatttat attcagaatt gaatttctta
      661 taagctttat tcaacatcat atatgccaag aacacccata ggtaacgcat tggcatgaca
      721 actgagttca agttcgtcaa ccattttact aattcattca tatctttgat accaaaaatc
      781 ggcaacaaaa taatgattcc tactagtata cctgtcagaa gataaccatt caccaatgta
      841 cctttacgat tacgtttacg tagccagttt ggtacaaatt ctggatccgc atctgctaac
      901 aagattttta gtggtgcatc aattgaaaag gctaatgcgg agatttgtcc aatcatgttt
      961 gtcaatgcgt aaatgatcat caatgagtta ccgataccat agtaattacc taaaatttga
     1021 aaagcactgt atgccccatt tgccatcaag tctttaggaa tattatcact agcaaacagc
     1081 atacccattg cgactgagcc taatacagca caaatcccta ccattgctgc taagaagatc
     1141 atccctttag gaaattcctt tgcaggattt cttgtagagt tgacataagg ggatattttt
     1201 tccgcccctc caactgcaaa tactagcatc gaaacggttg tgaaataact gaaatcaaat
     1261 gttggaatat atgttttcac ttgattcata tgtggtgtgg caaattccat cgttggattg
     1321 atgaacggtg ccgttacagc taaaagaata aataagatcg acatgacgaa catcgctgtt
     1381 ccggccagtc cgccaatcac tttcaaagta gaaagtcctt ttgttgataa atataaaaag
     1441 gcaagaaata taataagtga aataactgct accatttgta ctgacatcgt atttacgata
     1501 tttccatttc cttggactgc ccaaccacca gcaatcagaa ttgcttgagg cttttgtgcc
     1561 aaataaggaa tatggacgac ccagtaagtc caagcggcat agtatgccag tcgtttatta
     1621 gatgtcgtat tttcgaccca tgaactgacg cctcctttac tatccttgaa ggctgatcct
     1681 aattgtccaa cgatcaatgc gtatggaata aaataaatgg ccaaaatcaa tagccaagag
     1741 gtgacaactg atactccttg ctgagcatag ttattaacta cattccccat gccccaaacc
     1801 atgttaaatg caattaacgc aacagtaaac cagcgtaatt gtttgttgtt cattcgttct
     1861 ctcctttatg ataaaaattt gttatccaga tgtaatcata ttcaattttt aacaaactta
     1921 caagacagtg ttattttatg tgtgtattct tttatttaat acacatcgtt ttttcatatt
     1981 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
     2041 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
     2101 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttttt
     2161 ttacatgcaa gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa
     2221 atactgcatc tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta
     2281 tcccaatagc aaagacaatg ttttgtttga cgattttcaa tgttttcttt gctaaatgga
     2341 ttgcttctgc aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg
     2401 cagcatcgct tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg
     2461 catcgttgat tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct
     2521 ctaaccgctg cactttatct tcaggaagca attcgctata tatcttgtcc acgcctactt
     2581 gcttcccgat atgatcagca atttttttcg agtcgcccgt caacataact gtgttcttca
     2641 caccagcctg ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa
     2701 taacaagata accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt
     2761 gacttaaagg aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt
     2821 gtttgccatc aacttcagct aagatccctt cacctgcaaa ttcctggata ttagttgttg
     2881 gtaaaagcgg acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact
     2941 gttctgcact cgcaatatat tgcatgaatt tctttggatc gatttttgta tcgatcgtct
     3001 ggatcgaaaa gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcggttt
     3061 gcgcaagcaa ctccaagtaa tttgaacctt ttactaatac accgatttta cttgcgcctc
     3121 cgataccgcc aaagaaacta agtggcacgg aaatcactaa tgcacatgga catgagatca
     3181 ctaaaaatgt caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg
     3241 gaggtaaaac agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga
     3301 atttagtaat gaaattttca gctggtgctt ttttactgct ggcattttct actaattcta
     3361 ataatttgct gatagtagaa ttttcataag atttttctac ttgaactaaa aatggtttat
     3421 ttttattgat aaatccgctt aatactgttt caccaacata tacagattta gggactgatt
     3481 ctcctgtaag tgctgacgta tcgactaatg attctccttc gatgatcgtt ccatctaacg
     3541 gtacacgttc accaggcttc acaagtacaa actgaccgat ctgcacgtct tcagggttca
     3601 cggtcatcaa tccttccgtc gtctgcacgt gagctgtttc tggacggatc gccatcaatt
     3661 cgcgaatcga ttttcttgaa tgactgactg ccaatccttg gaaatactcg ccgatttgat
     3721 aaaatagcat cactgctacg gcttctggat attcaccgat caacatagcg ccaatcgtag
     3781 caacagacat aagaaaattc tcatcaaaga tttttccttt gacgatattc atcactgcct
     3841 tcttcactac atcatatcct atcagcagat aaatcaataa ataccctatc aagcgaattg
     3901 gttcattaaa atcaaataat agcaataaag cgatacctgc aagggaaaat aaaatccgga
     3961 acagcgtatt tctctctttt tcatttccat gttcagatac tttttcctta tctatttctg
     4021 ttactttgac atctggttct aattccttca ctactttttt tgtttcttgt tcaatcgtag
     4081 ccaaatgatc ttcctctgcg tcaatcgtta gttttccaga agtgaagttt accgttgctt
     4141 ccttgactcc attgatcttc tgaactcctt tttcgatttt cattgcacag ttcgcacaat
     4201 ctaaaccttc taatctgtaa cttttcattt taatgacctc ctcgcctcaa catatgaaca
     4261 tctcttcata actaattata aatgaatggt tattcatatg tcaaggtatc cgaaagaaaa
     4321 aatgaaaaac atctgcatcg gaaaattt
//
LOCUS       DAFTHM010000153         4326 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFTHM010000153 DAFTHM010000000
VERSION     DAFTHM010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.154"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(17..538)
                     /locus_tag="L7C88_002677"
     CDS             complement(17..538)
                     /locus_tag="L7C88_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBP9559458.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            737..>4326
                     /gene="nifJ"
                     /locus_tag="L7C88_002678"
     CDS             737..>4326
                     /gene="nifJ"
                     /locus_tag="L7C88_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBP9559459.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKT"
BASE COUNT         1352 a          815 c          952 g         1207 t
ORIGIN      
        1 cacgctcctt atttttttat tttgtttgga tcaattcttt taattcctct attgaaatag
       61 attcatcaaa gatttcttta cccaagatga cagttggaac aaatcgaata tgtgcttgct
      121 cagcttcgtt gatgacagct tggctcagct gttcgtcttt ttgttctgtc agctttagtt
      181 tatctactgc aaaatccgct acttcttgga gagaaagatg tttccactcg tcttgagtat
      241 cgaatatttg tttgatctct ttgatcgctt tttggccatc gctgattgtg agataccggt
      301 gcatcacgtt ccctcgctgt aagctttctt tttctttatc gaacaatttg atcactcgct
      361 gcaattgccc gctttggact gcttcttcta atagctcata agattcttca aaccattgtc
      421 ggcaatacgg acaagctaag ttgatgaatt cgaccatttt tttaggagca ttcgatgaac
      481 cataaaggat tcctttttgt gtatttgttt tcgttgcatc aatcactgat atatccatgt
      541 taaaacacct ctttcgctta tagtttatac atgtctgaca aaaaaaggca acgatttaga
      601 ctgtttgtct aaaaattaga tgaccaattc aaatagatac atgtaaaata tttttataaa
      661 taaaagaaaa aaatggcatg ttttacgtta taatggaaca gataataaga gagaatatga
      721 acaaggatga tgaatcatgc gaaaaatgaa aacaatggat ggcaatacgg cagccgcata
      781 tatttcttat gcatttaccg agattgctgc aatatatcca ataacaccca gttcgaccat
      841 ggctgaatta gtagatcaat ggtcagcagc aggaaaagaa aacgtattcg gtcaaccagt
      901 aaaagtagta gaaatgcaat ccgaagcagg agcagctggt gtggtccatg gatcattgaa
      961 aactggtgca ctgacaacta catataccgc ttcacaaggg ctgcttttga tgataccgaa
     1021 tatgtacaag attgctgggg aactactgcc aagtgttttc cacgttgcta gtcgggcagt
     1081 gacgacaaat gcgttgaata ttttcggaga tcacggagac gtgatggctg caagacaaac
     1141 aggatttgct atgttagctg aaagcagtgt acaagaagtg atggatttag cacctgttgc
     1201 ccatcttgct tctattgaag gagaagtccc ttttttgaat ttctttgatg gattccgtac
     1261 gagtcacgag attcaaaaaa tcgaagtttt ggaatatgaa gaattagctc ctctgatcaa
     1321 tcaggagaaa ttagcttcat ttcgtaaacg agggatgaat cccaatcatc cgactgttag
     1381 tggtacgaac cagaatccag acatccattt tcaacaacgg gaaacgatca acccctatta
     1441 tgataaatta cctgaaatcg ttcaaaaata tatgaaagag atcaaccgat tacgaggaac
     1501 ttcttatgac ttggtgactt attacggagc agacgatgcg gaagaagtca ttgtttctat
     1561 gggatcagtt gcacagacga ttgaacaaac gattgattac ttgaatgcaa acggacggaa
     1621 aacaggtttt ttgaatatcc atctttatcg tccttttcca gtggaaacat tcgtgcaaaa
     1681 gttgcctcat acagtaaaaa caattgctgt tcttgatcga agtaaagaac caggggcagg
     1741 tggagaacct ctcttattag acgttcaaag tgcgttatat gattctgaac ttcgcccggc
     1801 tgttattggt ggtcgctacg gattggggtc taaagatgtg actcccgacc aaatctcagc
     1861 agtttttgat gaattgaaaa aagacccaag catacgcaaa aaacggttta ccatagggat
     1921 cgtggatgat gtgacttatc aatctttgga accaaaggaa agtctggatt tgacagaacc
     1981 gcaaacattc caggccaagt tttggggatt tggatctgac ggaacagttg gagcaaataa
     2041 atcagctatc aagattattg gagatcacac cgataaatat gcgcaaggct atttttatta
     2101 tgattcgaaa aaatctggcg gtctgactgt ctctcatctt cgttttggag atacgccgat
     2161 acgttcagcg tatcttgtcg agcatgcgga ccttgttgcc tgtcacacac cagcttacct
     2221 gcatagctat gacttggtca aaggattgaa gccaggtggc atttttttat tgaatactct
     2281 ttggagcgac gaacaattag aaacgcatct gcccttaaaa ttaaaacgtt acttggctga
     2341 aaataacatt agattctata cgatcaatgc catgagattg gcccaagaag tcggtttggg
     2401 acgccggatc aatacggcaa tggaaacggc tttttttaaa ttagctgaca tcattccttt
     2461 tgatgaggtg cttccgctgc taaaagaaga agccctgaaa agctatggac ataaatcaat
     2521 ggctatcgta gaaaaaaaca tacaagcaat cgatcggacg accgaactgc ttcatcaagt
     2581 cgcgatccca gaccattgga gaacgttgga gatgcctgaa aaaatcaata aaaggaacac
     2641 tggttatata caagaaatac ttgaaccagt gaatgcacag gaaggaaatc aactctctgt
     2701 tggtacactt gtagcaaatg gaatgacaac tggcgaaatg cctttaggaa cggcttctat
     2761 ggaaaagcgg ggcgtcgctt tagaagtacc tgagtggatt agtgatcgct gtacgatgtg
     2821 taatgaatgt gcctttgttt gtcctcatgc tgccatccgt ccatttttag cagatgaaga
     2881 ggaaatggaa gaagcgccag aaggatttat cgtgagagaa atgcgaggcg cagacggcgt
     2941 aaaataccgt atccaagttt cagtggaaga ctgtacaggt tgtggtctgt gtgtagaggc
     3001 ttgtcccgca aaagaaaaag ctttagtgat gaagccttat gaagaacaga aagaacaagc
     3061 tgtgaattgg gcttttgcaa tgacattaag acaaaaagca aatccagtca aaggaaagaa
     3121 tactgtcttg tctacacaat tcaatcaacc gcttcttgaa ttctcgggcg cttgctcagg
     3181 ctgtggcgaa acaccttatg taaaattatt gacacaaatg ttcggtgatc gaatgatgat
     3241 cgcgaatgcg acaggctgtt cttctatttg gggcggtgct tctcctgctt ctccttatac
     3301 gaccaatgaa tgtggtcaag ggcctgcatg gtcaaattct ttattggaag ataatgctga
     3361 atttggttat ggtatgcttc tagcggcaca gactcgtcgc gaggctttgg caagttcaat
     3421 caaagaagta ttgccaaaag tatcagaaga actacgagaa ttgatggaag actggttagt
     3481 acacatgttt gagagtgaag gaacgcagca aagagcagca aaactgcaag ctgcgatcga
     3541 aagcgaacga tcaattttcc ctgaactgga ggatatatac aagagaaagg atctattcgt
     3601 aaaaaacagc caatggatga ttggtggaga cggatgggct tacgacattg gttttggcgg
     3661 gatcgatcat gtacttgcca gcggagcaga cgtgaatatc cttgttttgg ataacgaagt
     3721 ctattccaat actggcggtc aaacctcaaa agcaacacca gcttcggcaa tcgctaaatt
     3781 ttcggctagt ggaaagtatg cttcaaagaa agatctagga atgatggcga tgacatatgg
     3841 aaatgtttat gtggcgcaaa ttgcttcagg tgccaatcaa atgcaaacga tcaaggcatt
     3901 tgaagaagca gaaaagtatc ctggtccttc tctgattatt gcctatacgc cttgtatcac
     3961 acatggcttg cttggcggaa tgaaagaatc gcttaaagaa gcaaaagaag ctgtttcttc
     4021 tggttattgg tcattatatc gatataaccc tacaatggtc gaaaaaaaca agaacccaat
     4081 gactttggac tacaaaaaac ctgatttctc tgctatgcct gatttcatga ggaaacaagt
     4141 tcgcttttcc tcgctagata acgcaaatcc aaatcttgca aaagctttat ttgaaaagac
     4201 tgtccacgac gctaaaacac gtttttacaa ctatgctgca ctgacgggag aattagaaaa
     4261 aatcaagaaa cgacttgaac cagaggaatc tatcgatgta cccgttaaga ctagaaaaga
     4321 aaaaac
//
LOCUS       DAFTHM010000154         4310 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFTHM010000154 DAFTHM010000000
VERSION     DAFTHM010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.155"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(65..1285)
                     /locus_tag="L7C88_002679"
     CDS             complement(65..1285)
                     /locus_tag="L7C88_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBP9559460.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1305..1916)
                     /locus_tag="L7C88_002680"
     CDS             complement(1305..1916)
                     /locus_tag="L7C88_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBP9559461.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1959..2891)
                     /locus_tag="L7C88_002681"
     CDS             complement(1959..2891)
                     /locus_tag="L7C88_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBP9559462.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3312..4172)
                     /locus_tag="L7C88_002682"
     CDS             complement(3312..4172)
                     /locus_tag="L7C88_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9559463.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1230 a          866 c          707 g         1507 t
ORIGIN      
        1 agcttaaatc atagataccg taagggactt tattctttat ttaaaacttt gcaacagaac
       61 ctttttattt tacagaagca ctcgaaactg catctactgc agtttcatcg tgtgtgctgg
      121 cgctggttac tgcatctgtt tttccaccat gaacagatgc acttgaaacc gcatcttcat
      181 ttccaacaag ttgttgaccc gtttgttgta aataccactc aatgattggt ttgaaatcaa
      241 gaatgtattc attgattcca gcatactctc cattttcatc atgcattgct tggtaattat
      301 gcacaatata tttttctggc acttgttttg gtacatgaac acgtaccgca tctgttgctc
      361 cgcttcgcag ttgttgaatt acccactcta catttttata cgatttttct gggtgacagt
      421 tggctaatgg attccctacc tgaccgggca cacgagcagc taacatctct ttcgcttctt
      481 ggcgcaaatt ataatataaa aattggttat tattatctgc aaaagttaat tccatcggca
      541 tcgaatctaa aaagtaattg atttgatcca ctgtcaataa cccacgattt aatttgacgt
      601 aagtatttcc agaaacggca ccgactgctt cagaagcttt ttccaaccaa tgatcatctg
      661 acatatcaac atcgggtatt gtcgtagcaa ttgttcctgt cgcatgcaaa tcttctggtg
      721 gaagcttttt aggccctgct aaggtagaca cgactttaat gaattttaca aaacttgcta
      781 atgtactgcc taaaaagtca acagttcgtg gatcaatcaa gcgatcttct tggtcaaatg
      841 cttcttttgc ttttcccaat aaaaattcat ttccgggcat cactaatgca ttcacgcctg
      901 gtgcgtccaa aatttggcgc aagtgtaatt gcgcgcgtga agttccttga tcgtagtaag
      961 aagcacccac aaccattaca ggtttatttt caagtggatg gattttaaat gatagccatt
     1021 caagtgcact tttcaatcct gctggaaccg tatgattgtg ttctggcgta gcaataatta
     1081 ccccatcagc cattaagatt ttgcgattta gctgttgaat agcaggacta tttgtttgat
     1141 catcatcttg attgaacaga ggtaaatctt tgatttcaat gatttctaaa ttaaatagtt
     1201 catgatattg tttttggata aatgttaata atttacggtt atatgaaagt tcagctgctg
     1261 atccgacgat acctattaat ttcatctttg tttgctcccc tcgattaaat cgtttcccat
     1321 gaaaagcttt cggcttcacg tttatttgct tggtgcgcat gttgcaattg actagtgatt
     1381 gtgacaaaga gtaagaaatc tttgaatagt tcacgtaatt ttgcgacttg ttcttcatca
     1441 atgagtcgtc cttgctcatc aaaggcttgg agtgaatgac ccaataaaaa ttctgagctt
     1501 ggcataattc gtgcctttaa ctctggtgaa tccaatattt ggcgcaaatg tgcttgtgcg
     1561 cgtgaagaac ctaacgtgcc ataagacgct ccggtaatca tcactggttt atccacaaac
     1621 ggaaaaatac catatgaaag ccaatttaat gcgttaatca atgaagcagg aaccgcatgg
     1681 tcatactctg gtgtgctgat gattacgcca tctgcttgtt caatttttcc agcaatttct
     1741 ttaacaacat ttggtagttc tgtgttttca ggtttgttaa atagtggcag ctccttgatt
     1801 tcgacaattt cgatttctgc ctcatttaca aaataatttt tcataaactg taataattca
     1861 cggtttgttg accgcgttga atttgttcct actaatccaa taaatttcat cttcattctc
     1921 tttcctttct aacatcgatt tctgactgtt cgcacgtact aaattttttc aaatcctttt
     1981 gtatacaaga attgattctc ttttgttaca actgctccct cgatacccgg ctgttcttca
     2041 agcgctttca acacttctaa agaagatgct ccaaataaac gtgtagtcca gatttctcca
     2101 tctacagaag aatcagacaa aatcgtcagg cttgctacgt catttttaac tggaaagcca
     2161 gttttcggat caatgatgtg atgatacact gacgaaccat tttgtagata acgttcgtag
     2221 attccagagg taactaaaga ttggttgttt agtttaacca ccgcaagcga ctcttcacgt
     2281 gaacctttag gatttcgcaa accaatacgc caagcaccat ccgaacgtct tggtgattca
     2341 ccaaaaacaa cgatatttcc tcctaagtta actaaagcaa acgctgcatt tcgctctcgg
     2401 caatgtgtaa ttaatttatc tgcaatgtaa ccttttgcta acgcccccaa gtcaatcatc
     2461 attcctggtt tggttaaaaa aacggttttc attttttcat ctaattgaat ttggtgtgga
     2521 tccgttagca gaagtaactc agttatctct gcttttgttg gaaccaatgc atcttcaaat
     2581 ccaatgtgcc atttttgtac aaccggacca atagcaatat tcagataact atttcttgca
     2641 caactatgtg cttttcctaa tttgatgagc tcaaaaagtt caggatgtac aatcacagct
     2701 tgtcgtccag cagcttgatt gatggccatt aattcagaag ttgcatcatg tgcgctgaag
     2761 cgatgttcat aaacgtgcaa ccattcgcct aactctgcta gtaatcgact aggctcttca
     2821 tgcccaactt gtaatgtaat tgttgtcccc atcatttgcc agattttcgt ttcttcgatc
     2881 acctgattca ttttgtacct tctttacttg aactacggat tacatgagta attagttttt
     2941 atttttgtta ctgttttcac aaccagatga tacgcctgct agatttattt gtcaaccgat
     3001 tttatatatt tttttatata ataaggtaat tttaatataa aattttatat tgtaaaaaaa
     3061 caaataaggg aaacaaacaa cacatttttg tgtgttgctt atttccctct aactatcgtt
     3121 ttctatttga tggttaacct acttaaaata aatactgcaa cgacaaacgg agatcaagca
     3181 tgctttgtaa cgtattttac gataattacg actttatttt attactctat cttgctgcca
     3241 tacccgtcta tccctaatca tctttggtga attttttcaa agttagcata acaaaaataa
     3301 gtattttttc cttagttaat caatagtatc atttttttca tatgatttaa ttcatcaatt
     3361 aattttttgt ttttattaat tttagcaaaa gctagtgcat cttgaatcaa ttcgagcact
     3421 tctgccttcg acttattttt agcctgtgcg ttcttcgcta attgggcagc agctcgtgct
     3481 aagtaataag tcaaatggtt atccgaacaa atatcgattg cgtaatttag tagtgcatca
     3541 cttgtttcca aatcaccgtc ttgcgcaaaa aaaacaccac aatgaaagac gatatttaac
     3601 acccgccaga tatcttctgt tgtacgaatc ggatacgtat aaattttttc aaacactcga
     3661 ttgaaataaa cttctgcttt ttccaactct ttttctctag catagaccat tccaatacct
     3721 gtatatgcca ataaacgaaa caacgtgttg gctgtttctg ccatcaacaa ctgatcaaaa
     3781 tggaacaaca catccgtaat tggtgcattc gtaaaaatca tttcaaatcc ttttagatag
     3841 tagtaacgtg caatcagctc agactcgtca attaccttgg gatcaatggc tgctaaaatc
     3901 tgtgtcaatt gttcatattc actcgtaatc agtgaaaact ctgctttttc tagctgttca
     3961 tcaagttgtg tattgatcac gttcatcgaa gaaaaaagtt caactaacgg aagattgatt
     4021 cgattacata atttgattaa aatttttaac gaagggactt gaccattgtt ctcaaattta
     4081 cttaatgttg cttgtgtaca aattccttca gacacttctt tttgagataa gttggcagcc
     4141 tttcttgccg taataaattt ttcaatgttc attattttct ctccaatcag acctcacacg
     4201 aaaatcattt ctgtctcgat tttagcatgt tttctttggg aatgctttag gttctgttgc
     4261 aaagttttaa ataaagaata aagtccctta cggtatctat gatttaagct
//
LOCUS       DAFTHM010000155         4163 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFTHM010000155 DAFTHM010000000
VERSION     DAFTHM010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.156"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            9..731
                     /locus_tag="L7C88_002683"
     CDS             9..731
                     /locus_tag="L7C88_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBP9559464.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            789..2828
                     /locus_tag="L7C88_002684"
     CDS             789..2828
                     /locus_tag="L7C88_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBP9559465.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLLAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2937..4088)
                     /locus_tag="L7C88_002685"
     CDS             complement(2937..4088)
                     /locus_tag="L7C88_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBP9559466.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
BASE COUNT         1514 a          775 c          810 g         1064 t
ORIGIN      
        1 tatctatttt gttactgctt acattagtag ttggctattt ttcgattgag tttatccatg
       61 gattttcgtc tgcaaaacag agttcaactg tgaaaaaggt agagccgaaa agtatcccta
      121 ccacactaaa tgtggctttg attggttcag atgctcgttc gaaagacgaa aacggtcgct
      181 cggattcact tctggttgca caatacaacc agaaaacaca acaagcaaaa ctgatctcta
      241 tcatgagaga ttcatatgtc gatattccag gttacggaat gaataagata aatgcagctt
      301 actcttatgg gggagttgat ttattaaatc aaacattaaa ggaaaatttc aaatttgaag
      361 ctccctatta tgcaagtatc acatttcaag attttatcga ttgcgttaat gaactgtttc
      421 ctggtggagt caagatcgat gcagaaaaat ctctagattt agatggcgta tatataaaca
      481 aaggagagca agtgatggat ggtaatactt tactccagta tgctcgattt cgggaagaca
      541 aagaaggaga cttcgggagg atcagaaggc agcagcaagt gatcaaagct atctctcagc
      601 agctgaaaga cgtaacttca atattcaagc tacccaaagc ggttgggaaa ttacttggta
      661 gtatccaaac gaaccttcca gaaagtgtgc ttctggattg tggtatggat ttcctcaaag
      721 acatatgtta gaataaacag gtataaatag tgaaataaag gaatgacaag caagagaagg
      781 aggaaaaaat gaaaagaagt gacaagcacg gcaaaaatcg aacaggcgct tatattgccg
      841 gcgcagtgat cttaatagca gctgcgggtg gcggttattt ttactaccag cactatcaag
      901 aaacccaagc agtagaagct ggagaaaaga cagttgagca atttgtccaa gctttgaaca
      961 agggagatta taacaaagct gcagaaatga catcaaaaaa ggcggcaaat aaaagtgcat
     1021 tatctgaaaa agagatctta gataaatacc agaatatata cggtgctgct gatgtcaaag
     1081 gacttcagat atcgaatcta aaagtagata aaaaagacga ttctacttac agtttttcat
     1141 ataaagcaaa gatgaatacc tcattaggtg aattgaaaga tctttcttat aaaggaacat
     1201 tagacagaaa tgatggtcaa accacgatca actggcaacc caacttggtt tttccagaaa
     1261 tggaaggaaa tgacaaagta agcctgacca cacaagaagc agcaagaggg aatattatag
     1321 atcgaaatgg tgaaccatta gcaacaacag gcaaactaaa acaattagga gtcgttccaa
     1381 gtaaacttgg agatggaggc gaaaaaacag ccaatatcaa agcgattgct tcctccttcg
     1441 acttaacaga agatgctatc aatcaggcga tttcacaaag ctgggtacaa cccgattact
     1501 ttgtcccatt gaaaatcatt gatggagcaa cgccagaact tccagctgga gctaccattc
     1561 aagaagtaga cggcagatat tatcctttgg gtgaagcagc tgctcagctg attggttacg
     1621 tgggagatat cacagcagaa gatattgata agaatccaga attaagcagt aatggaaaaa
     1681 tcggtcgctc aggtttggag atggcttttg ataaggatct tcgtgggaca acaggtggga
     1741 aattaagcat tacagatgca gacggtgtag agaaaaaagt tctgatcgaa catgaagttc
     1801 aaaatggcaa agatatcaaa ttgacaatcg atgcgaaggc acaaaaaaca gcttttgaca
     1861 gtctaggagg aaaagctgga tcaactgttg cgacaacgcc aaaaaccggt gatcttcttg
     1921 cgcttgctag ctctccaagc tatgatccaa acaaaatgac aaacgggatc tcacaagaag
     1981 attacaaagc ttatgaagaa aatcctgaac atccattcat cagccgattt gcgacaggtt
     2041 atgctcctgg atctacgttt aaaataatta cagcagcaat cggtctcgac aacggcacta
     2101 tcgatccaaa tgaagtgttg acgatcaacg ggcttaaatg gcaaaaagac agttcttggg
     2161 gatcttttca aacaacgcgt gtcagtagtg atgtatcaca agtagactta aaaactgctt
     2221 tgatctattc cgataatata tatgcggcac aagaaacgtt gaaaatgggt gagaaaaaat
     2281 ttcgtacagg cttagataaa ttcatttttg gtgaagacct tgatttgcca attagtatga
     2341 atccagcaca aatttctaat gaagatagct ttaactcaga tatcttgcta gctgatactg
     2401 gatatggaca gggcgaactt ctaattaatc ctatccagca agcagcaatg tattctgttt
     2461 ttaccaacaa tggcacactt gtctatccta aattgattgc agataaagag acaaaagata
     2521 agaagaatgt catcagcgaa acagcagtac aaacgatcgt gccagatctg agagaagttg
     2581 tgcaagatgt aaatggtaca gcacattctc tttctgcttt agggattccg ttggcagcga
     2641 aaactggtac agcggaaatc aaagaaaaac aggatgtaaa ggggcaagag aacagtttct
     2701 tgcttgcttt caatcttgat aaccaaggtt atatgatggt cagcatgttg gaaaataaag
     2761 aagatgatga ttcagcaacc aaacgagcat cggaactatt gcaatacctc aaccaaaatt
     2821 atcaataaaa aattgctttt taagtacagt aaaaggactg tggcgttatc gtcacagtcc
     2881 ttttttcaaa taaacggttt tcacgatgtc tctttcacaa cttctttttg atttactcac
     2941 acttcataaa ctttttttgt aaaatatttg agaacaagtg gagaaataag tgtacttaat
     3001 aaaatcacga taactaaagg tgaatagtac tgtggttcga tcaattgact ttgctgtcca
     3061 atttgtaaaa tgatcaaagc catttctcca cgcgaaatca taccagcacc gaccatcaat
     3121 gaactatgtt gagaaaaacc ggcaatctga gcaccaaaat aacctccaag caatttggtc
     3181 aaaatcgcta caagcgtcaa tatagaaata aagagtagtt gttcactaaa gtcagaaaaa
     3241 tcaacttcta atcctacact gacaaaaaat actggtataa atactgcata tcctaaagcc
     3301 tctacattgt ggtatacttc ttctttaacc tttgtctgac tgacagctat cccagcaaaa
     3361 aaagcaccaa tgacagagct aagcccaaca agatccgcta cgtaagacat tcctaaacaa
     3421 ataactagcg atacgatgat aatagaagaa tttgcgtaca ctttttctgc aaatgaaagt
     3481 aggaaaggcg caatccattt gactaataag aaaataaaaa caaaataaat tagctgttca
     3541 atcaaaacaa gcggtaaaga agcattgcta gaagcttccc ccgttagaaa agataggctg
     3601 aaacttagaa ctaaaacgac taaaatgtca tctaccacag aagcacccaa aattgttgat
     3661 ccttcttttg tattcactac gtttagttct tttaatactt ctactgaaat actgacagaa
     3721 gttgccgcaa gaataatccc aaagaaaatc gcttcatttc ccgaaacttg gaatgctttg
     3781 cctgtcaacc agccaaaaac aaccgggaag atgatcccaa gcaaagcaac gaacatacca
     3841 ggtcggaaat attttttcaa aagagataaa tcactttcca gaccagctaa aaacattaat
     3901 aagatcacac caatctccga aaagtcatgg actagaatat caggtttgac ccaattcaat
     3961 ccagcttggc ctagcaaaac accaacaagt aattgtccaa tcactgctgg gatacctaat
     4021 ctccgcgaga tatgtgagcc aatcgttgtt gaaatcaata tcaggcataa aataccaata
     4081 aattccattc tcatcattcc tttgtataaa atatagcccg aacttagcat aacatacatt
     4141 attgaaaaaa taggaaaata tac
//
LOCUS       DAFTHM010000156         4107 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFTHM010000156 DAFTHM010000000
VERSION     DAFTHM010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.157"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..555
                     /locus_tag="L7C88_002686"
     CDS             <1..555
                     /locus_tag="L7C88_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559467.1"
                     /translation="DLQERGLKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRN
                     ISHKVRVDDRKEVCDDFKMVYQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLL
                     TFYDFPLAIRKSIYSTNLIESFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFL
                     GRSHKGFQQAEGELEQMLSQLIEN"
     gene            689..2878
                     /locus_tag="L7C88_002687"
     CDS             689..2878
                     /locus_tag="L7C88_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9559468.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            2875..>4107
                     /locus_tag="L7C88_002688"
     CDS             2875..>4107
                     /locus_tag="L7C88_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBP9559469.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILII"
BASE COUNT         1512 a          589 c          710 g         1296 t
ORIGIN      
        1 gaccttcaag agcgcggttt gaaaaatgtc ctcctgttca tcacggatgg cttaaagggg
       61 atggtaggag cgattagtcg gttctatccc aaagctcgtt ttcaacattg ttgtgtacac
      121 gtttcccgta atatcagtca taaagtgcgt gtcgatgatc gtaaggaagt ctgtgatgat
      181 tttaaaatgg tgtatcaagc ctcatctaaa gaggtggcgt tggaagcacg tggtactttt
      241 gcggaaaaat ggaaaaccag ctatccaaaa gtggttgaat cgattctttc gaacgatcac
      301 ttgctcactt tctatgattt ccccttggcc atacgcaaga gtatttattc tacgaacttg
      361 attgaatcct ttaataaaca aatcaagaaa tacagccacc gcaaggaaca gttccaaaat
      421 gaagagtcga tggaacgttt cttagtctcg tcttttgata cttacaacca aaaattccta
      481 ggtcgcagtc ataaaggttt ccaacaggcc gaaggcgagc tcgaacaaat gctaagccaa
      541 ctgattgaga attagaaaca atctgcagta gggaagaatc atttacacaa aattattgac
      601 gctcccttat aatgagaact tttactaaca taatttatga taaacttact atataatcat
      661 attaattaaa tagttaggag atctgcttat gtttatatct actcttcaaa ttcgaaattt
      721 tagaaattat gaatccgaaa tctttcgatt cgataatgag acaaatacta ttataggtga
      781 gaatgattca gggaaaacca atgctcttac tgcattgaga atcttattag atgatagtta
      841 ttactatagt agtaaaacac taaaagaatc agattttttt catggaattc aaaatgggtg
      901 gcaagggcat tggattatta tctctgcgac atttgaagga atcagcgaag aagaatttga
      961 caatgagatt tgtgcttcca tttctttaaa ttctgaaagt caaacaatct tagaagaatt
     1021 gatttcaaat gcagataaag gtgtaggtag tatttctcta tttattagac ctaacaaagc
     1081 tattagaaag caattatttg atatttccac tgaattagac tctcatcaat ttaacgaatt
     1141 tagaaattct attcgtctat ccgactatga attttactac acatctaaat caaatctaaa
     1201 tttctgtatc aatgaaaatt atgataaatt ggtaggaaga ctcaatgaca atatagctag
     1261 taatcctgaa gaagacgatg aagctctgtt gggctcaaga attgacatgt cagatatttt
     1321 caagcatatt tcggttgttt atgttgacgc tcttcgagat gttcttagag aaatgaaaaa
     1381 caatcgaaac ccagtcaaaa gaatcatgga aacaattgaa tcaaaaatat catcagataa
     1441 tgttgagtca ttaaaaacaa ttatacagca attaaatgag actattacca gtgttcctga
     1501 aattaggaaa attggcgaaa atattaatcg gcaactaaat agcataattg gttcagtgta
     1561 ttctcctaat cttcttcttt cctcaactat gtcagatgat atgggttctt tagcaaaatt
     1621 tctttcaatg aagccagaac aaaatatcga cttagactta ctagggttag gacatctaaa
     1681 tatgatttat ttagctttga aaatagtcga atttgaagcg tgtcgttcaa gagaactact
     1741 taatattatg ttgattgaag aaccagaagc tcatattcat catcatattc aaaaaactct
     1801 gttcgaagga ttaaatcttc aaaaaaacta tactcagatt ctcatgacca cacattctgt
     1861 acatttagct gaagtgtctg aaatatctcg gatgaatgta ttaaaatcgt ttaatggcaa
     1921 atctatcgtt atgaatccag caaataatct gaactcattt gctaaagaaa agttaaaaaa
     1981 gaacaatcta aatctaataa acgcagtaga gagatattta gatgttaaaa gaaatggatt
     2041 gcttttttct aaaggtgtta tcttagttga aggagatgct gaagaaatac ttattcctca
     2101 aatagtaaaa aaattatttg gtataaactt agacgaactt ggaataggtt tgattaatgt
     2161 tggtagtact tcgtttgaat atatcgctag cttgtttgac gatgatagaa tacagagaaa
     2221 gtgtgctatt gtaactgatt tagatgaaca ggcaatccca tcagaacatc gattgtataa
     2281 aagcactgca caagagaaag gtcaagcaag aaaagaaaaa ttatcctccc tttttaatga
     2341 aaacaattgg gttaattgtt tttatgctaa tacaacattt gaaattgagt ttttagatgt
     2401 gaataaagaa aatattctaa cttatgtcag tccaattata gatgacgcat tcaaagataa
     2461 aaaaacaata actgcttata aagaagaaat acaaagtgaa caatatttag aaagaaattt
     2521 agcgatgtta aaactagcca atcatgttgg taaggggtgg tttgcaattg agttaggtga
     2581 aaaaattgac tttttaatca aaattcctaa gtatattctt aatgctattg cttttgcatg
     2641 tcaggaaata gtagatctct caatttataa aaaaattcta ctccatacaa tcgacttgta
     2701 cgaggaaact acagaattgt cagctttatc agctagttta aaaacaagtg atacagctga
     2761 tttgaatata gcaataattt ctttattaga gtactttggt aaagatgagg atgttgtgta
     2821 tctaatcaat cagatagaaa attacacaaa aatactttat gctgaggttt caaaatgaca
     2881 aatatcttcg aaaaaatcgt aaatgattta aatttagaac aaaaagatgt tgtggaaagt
     2941 gaagataacc tttatgtaaa tgcatgtcct gggagtggga aaacaagggt acttacaagg
     3001 aaaattgctt accaagcaat taaacacgat ggatcactaa aaagaataat tgctatcaca
     3061 tacactaata gagctgctga agaaattaag gaacgcctaa gtttacttag tatagatgat
     3121 gatattaata tttgggtggg gacaatacat cagttttgtc ttgaatttat tatttatcct
     3181 tttaaaatga atctctcaag agtatcaaaa ggatttacaa ttattgatga ttatactcaa
     3241 agagcttacg tcagccaaat taataatatg ctgaatttaa atctcaaaac gtatgaactg
     3301 aacaaaattg atttgtcact ttctcatgat tttaaaatta atgaagttca gtatactcaa
     3361 gtttctgaaa tgtatcacac tatgttggaa aaaaataaag aaattgattt tgatatgatt
     3421 ttactagtag cgtataaaat tttaactgta aacagtaacg ttgcacgtaa tattgctagt
     3481 aatataaggg cgatttatgt ggatgaattt caagatacta gagaattaca atacaatgta
     3541 atagctaaat tacttcaaaa caaccctcaa attcagtcaa tgtttgttgg agatattgac
     3601 caagcaattt atggatcatt agatggtata gctaaatcag ttgaagaact agaaatgcta
     3661 actagtcaca cttttcaatc aaagacgcta catggctgtt acaggtctaa tcagagatta
     3721 gtagacttct actctaattt tcagagttgt ccttacgaga ttgaaagcag agggaataat
     3781 aaaaacgacc gtggttttat aagttatgat tgcaaagtta ctaaggagga tttacccaac
     3841 ataataaaaa atataataaa ggaaaagatt gaaagcggca ttcatgaaaa agatatttgt
     3901 gtacttgctc ctcaacacta tcctctgttt tcactgggtg agtatttaaa gaaagaatta
     3961 ccgtattgca attttgatgc tataaatata tcaccaatta aggtaaataa tcatagttta
     4021 tttttcaagt tagcaatttt gtactttact gaatcaggtg aaaaggttcg aagaagaaag
     4081 ctaattgcaa acgatatttt aattata
//
LOCUS       DAFTHM010000157         4031 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFTHM010000157 DAFTHM010000000
VERSION     DAFTHM010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.158"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(237..386)
                     /locus_tag="L7C88_002689"
     CDS             complement(237..386)
                     /locus_tag="L7C88_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559470.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            848..1060
                     /locus_tag="L7C88_002690"
     CDS             848..1060
                     /locus_tag="L7C88_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559471.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1338..3137)
                     /locus_tag="L7C88_002691"
     CDS             complement(1338..3137)
                     /locus_tag="L7C88_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBP9559472.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3261..3857)
                     /locus_tag="L7C88_002692"
     CDS             complement(3261..3857)
                     /locus_tag="L7C88_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBP9559473.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1447 a          711 c          689 g         1184 t
ORIGIN      
        1 aaatattata cagataataa cggaatatta tcatcgaaac agctaacaaa attgtcataa
       61 aaaacgagat ggttgatatt agaacttgtg tttttgttta ggtctagaga taaagagaga
      121 caatttccaa atatatgtaa tgaatacaaa aagacgtttg tcgcggatta ccgttacaaa
      181 cgtcttttat tgattttccg agatctcatc agtcgccatt tggaatggtt cactccttat
      241 ctagattcgt ttaatgctcg gactgcttgt tcgattgtaa taccaaacgc aacgttattt
      301 tcgttttgtg catcaatcgc cataaaacgg ttagaagttg tatcaaaagc tacgcggtat
      361 tgcatatttg tttttgtaaa cgtcataaaa ttcatctcct ttgtaatgta atttagttct
      421 tgaaagtttc ctttaaactt tcgaacttat accaagttta gcatcgtacg ttttttgatg
      481 caattaaaaa gcatttatca ttttccttat ttattttttc ttaaatggtt tagctatttt
      541 cttttaatcc gataagtagc ccaatcatca aggttacaaa tactattgct tgaatataaa
      601 tcatatgctc acctctttat aaataactta gcaatataaa gaaaaaaacg cacgaacaac
      661 ataggaatat aaacaaacgt ttttgtcaca acgtctaaga tcgtgttaaa aaatagttat
      721 ctaaaaagca gaaagatact caaaataaaa aataaaaaaa tggataaaaa cgttttcaaa
      781 tacaaggtaa tttgttatta taaaataaag aaaaaacaaa ataaaaataa agaaaagagg
      841 gaatgaaatg gtaaaagcag aagtaggaag atcttatata tgcaaaccga tcggagtatc
      901 tcatgaacta atcggctgta ttgaacgtac atatatcaac acggctgtcg tgtatgttga
      961 aagttatgac caacgagact atcaacttat caatgaaagc aagtatcgca tgctcgtaaa
     1021 attctgtgat attagcgcac ctgctgaatt ggtttcttaa acagtatttt tgagaattcg
     1081 caagaactcc cttataatat aaataaagac agaagggagc gagaagatat gccaaaaaga
     1141 aaaagttcag ggaaaatggg aattattctt gcagtgatct ctgcaattcc tgctatttta
     1201 gctattgttc gtgcgatgaa ggaatcaaga gaaagttaag cacacattat gagcgtcaaa
     1261 caaaaaacgc atatacctgc ggtggcaggt tatgcgtttt ttgttgtata aagacttttt
     1321 tcattaacga tttttgatta gccgactccc aaaacaaaat ttagcagttt atctgaataa
     1381 gtgatttctt catctgtttg tttcacactt tcatttagta gtcccatctc atcggttatg
     1441 ataccatcca caccataaaa catcatgcga ctcatagcat ctgaatcgtt gattgtccat
     1501 acatatactt cttttccgtc ttggtgggca gaattaatga agttacggtt gatcgtacta
     1561 tattccattg tcagaaaatc agcaggcgtc acagggggcc caacaatatt gaaaggtaag
     1621 atgtagccca cataaaagtt tggttctgct tcttttaaat ctgaaacggt ttggtacgtc
     1681 aaactttgca aaatatgatg gttctctaag ataactttgc ggtatttatg gacaaatcgt
     1741 tcgacaaggt catccgaatc ttttttagag gtcttgatct caataagtaa tttttggttt
     1801 agcttatgtg ctttttccaa ataagaatca aaagaacaaa caggggcttg cactccgttt
     1861 tcagtaactg taagatttgt caattctttc aatgtaagat cctgtggtgt tccatttacc
     1921 cctgttaagt gacgaagatt tgcatcatgc atcactacga aatgaccatc ttttgtttcc
     1981 tgaacatcca tctctacata atcaggatga tagtctctgc ttgttttttc aagtgcttct
     2041 aaagtatttt gcgccccatt ttgggtactc acacctctgt gagagacagt cactggtttt
     2101 gtctgaacag ctgaagtcag ataatccata ttgtaaagac agacgccaat accgaaaaaa
     2161 actgcaaaaa gagtcaaacc agtgtttttc agcgcagaga aacgcaagtt gggggcttgt
     2221 gggataaacc acttagggat ctcaggcaag aagccttcgt catccatgaa atcaacaatg
     2281 atataaaaaa tccctacggt agacatcacg atattgaata ataaaatccc ttgtaaaagc
     2341 gtcatagcaa acacagcgct gatcaatgca tagtctggga aaaattgttc aaccatactt
     2401 tgtgccaaaa taacaacgat atatcctaaa gaagaaagga gtaaaatcgt accgccaatc
     2461 acaataaatt ggcccgtgat ggccaaaaga cgcgatttgg tcaatgacca gctttcccga
     2521 atggctgctc gaaaaggacg atctcgtaga atcatttccg gtaaagcaaa aatcagtcga
     2581 atcccaatat agccaaggaa aatataaacg agtaaaaagg aactgacgat gatccaacga
     2641 ttagcaaaaa taaaatccat aatgaaagcg gggattttta tttttgacag tagatcagaa
     2701 ttaaaactta atccgctgat cggtagaatc aataaaaaat aagcaaggaa aaacaaaaaa
     2761 gtaatgggtc tcactttctt cagctgaagt atcgtcaagt gtaagagttg cttcaaagag
     2821 attggttctt tctttttaat aaaaaaaaca ctcatcaaaa gaaaagtaaa ttcgaaataa
     2881 actaacagta aaatcgtcat caaaactacg attaacgaga gtagaacccc aggatgttga
     2941 gaaaaaattg aaggaatatt gtcataagac aaatagtcaa ttgcccctcg gtgtaaaata
     3001 aaacgggtcg tactgctcaa taagggtaaa caaataaata aaataaagcc atgcatcagc
     3061 aagacatcac ggaaataagc ttgtgttcct tttaaaaagt cccaagcatt acctaagcta
     3121 cgtttcaaat aattcatcct atcacctgct cttcacattg tagcgcaaat ctaatgaaaa
     3181 aggaaagggt gcagtgtgtt ttgcagaccc tttcccagat ttaacattgt caatcaatga
     3241 ctaattttac aaaataaata ttatccaaga agaccactta gatattgacc tccataaatc
     3301 aaggccatac tatataagaa aatcgacagt ggtttagcaa tcaaaatgat tagtgtatat
     3361 cgtttcactg acatgtttgt caatccagcc atcaaacata acgcatcgtc aggagcaact
     3421 ggaagaaaaa tagctagagc aaacagcttc tcaaaacggt tttgattatc cagccagcca
     3481 atatatttgt tatatgtctt atcgctaatc atggaaagta tgaatggctt tccataacga
     3541 cgccctagca gaaaaatgat aatcgaacca atgcagattc caatatagtt atagataaat
     3601 ccagcataag ggccaaatat caggacacca gctgcagtac tgatccctcc aggaatgatt
     3661 ggaataacta cttgcaggat ttggatgaag acaaaaataa tcggtcctaa aatgatggaa
     3721 tcacctacta atcctcttaa cgcattcaaa tctttgaaaa cacctaaatt aataaaataa
     3781 atcgtcagcg cgattgatag gcctaatccg ataatggata tgaaatttat cagttttcga
     3841 gaggcagcaa tattcattat tcatcaactc cttagaggtt ctttgttaac tatactttac
     3901 tagaaaagca actaactgcg ccattttttg atatgacaga aaacaaacaa ttttgtaagt
     3961 tcatcataag tataaaagat tgatctcaaa aaaacatcca actaaagact tatttaataa
     4021 cttgtttttt t
//
LOCUS       DAFTHM010000158         4021 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFTHM010000158 DAFTHM010000000
VERSION     DAFTHM010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.159"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(669..1226)
                     /locus_tag="L7C88_002693"
     CDS             complement(669..1226)
                     /locus_tag="L7C88_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559474.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1405..2016)
                     /locus_tag="L7C88_002694"
     CDS             complement(1405..2016)
                     /locus_tag="L7C88_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559475.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2129..2386)
                     /locus_tag="L7C88_002695"
     CDS             complement(2129..2386)
                     /locus_tag="L7C88_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559476.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2983..3261)
                     /locus_tag="L7C88_002696"
     CDS             complement(2983..3261)
                     /locus_tag="L7C88_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559477.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3295..3546)
                     /locus_tag="L7C88_002697"
     CDS             complement(3295..3546)
                     /locus_tag="L7C88_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559478.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1220 a          827 c          536 g         1438 t
ORIGIN      
        1 aacacttttg tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttct
       61 tatttcttgg agttaaacgc ttctgtccca gcctccttat tccgaataaa tggtgtccaa
      121 aagcttgcat ctgccagatt atctcatttc ttatgacaag ctaagcaaat tatctccacc
      181 aaataattta ttcatatttt tgacttgcgc atactaacta attcttaaat tttcatacaa
      241 aatttctcaa tttcccttaa cgagtaatat ttatgtacgg tgattctcac tagtatccca
      301 atcacttttt aagttatccc gatttcaatt ctacttcaaa aatagttgct tttatgtatg
      361 ctgttagttg attagatggt catttgttga gctaggtcgt ttattttaaa caagttgttt
      421 ctttagctta tacctatctc gtctaccaaa cgcaagatgg caaacacaaa tgcatacgca
      481 tctgtatttg ccactttgat tcgtataaag ctaacaacta ttaactcctc tcagctaata
      541 gttgctctct tttttattca gattcatttt tgctgatcac agcctagtat ttcaatggtt
      601 ttgaacacta aaccaaattg ttccattaca acattcactg gctgatgaaa tggattagta
      661 gatttcgatt attcaaagcg attttctatt ggtggatcgt gttcccaact aataagacgg
      721 attccaaacc tatcgtacag atcttctaaa ccacttataa attttgcacc tatttcaggt
      781 gttttattgc gtggatattc tattgttacg ccattaaatg gataccaatt aggattaggc
      841 tctctttttt tctgtacatc tcccatagaa tagttagcac tttctgggac ataatatatt
      901 cttcgaccat cctctaattc atctaataag atatttcgtg atcgtctatc acttgctaaa
      961 tgtagacgcc acgtgcgata ccatgccatg ctacctgcat ctgcagaaaa tccatcaaat
     1021 aatgcaacaa ttgtatcttc tatcacaatc ctttccccat ctacttcata ttctaatcta
     1081 aaatcaaact cccctcgggt aatttctggt cttggtggct taggacccaa tattattcta
     1141 cttaaaaccg cattcgttcc cagatgaaac acagctataa caacaataat gattaatatt
     1201 ttgtttctat ttgataaatt tctcattatt cgcacatcac ctctacattc tcacatatta
     1261 gttcgtaata ctcctttaat atcaaaatat ctactggtcg taataatatt cgctatgaat
     1321 tcctactact cgtataagaa aggccaaatc atcagctttt acttgctgat gatttggctt
     1381 gtttctattt atcgtaattg ttttctaatc accaaaattg ttaacaatcg gttcagatat
     1441 ttcccagttg attaaggtaa ttccgtattg tgtcaaaact tcttgcgctt ctccgaaatt
     1501 aagtacagtt cttatgtatc cactttctcc taatataaag tctacctctc ttttaaaacc
     1561 ttcctcgaga tttctaaggg ctatatgtgg ttttaatgac attgattgta cattttcccc
     1621 catataatat tgcgcacttc ctcgactaaa atagattcct agatcgtccc caaaaggtag
     1681 atcttctcta ccactagcta atctacttct ccatcttcgt tctcttttca tagaacctgc
     1741 gctgaactca cacccgttaa actcagctat gacagtatct tcaattatgt taatctgtcc
     1801 atctagttcg tattcaatcc taaatggaaa ttctccatag gtgatttccg gttcgggtat
     1861 tttaggtgag attaatgcaa agaaaggaaa tattaagctt ggcaacatca aaaaaactcc
     1921 tcctatgatc acaattcccg atgtaatcca aaatataatt tgtacaattc tcattgatcc
     1981 attgtattcc attttattcc ccctattact attcatatcc gcctatctat atcgatcttc
     2041 caatgcagag ataattgctt ccataccttg attttttact gagttaccta tgcgagatat
     2101 cattctccac taaggtgcat catattgtct atctaacatg attaattctc caataggtgt
     2161 atactcctcc aaaaacaaca tttaatgcat ctccctcgac aacataagct accatgtttg
     2221 ctgtatatgt gtttgagtct aattcataag cagataaatt tactgtcgct ggattaaata
     2281 taatcgcatt cgtatttata gctactgaat ttgctgcttc agcaccacct tttgaatgtc
     2341 cgatcattgt gatttcaata gtaggattta cgtggacagc cctcaccgtt taccctgacc
     2401 attatagaaa tcgcttactt ttttgaacta cgcaacaaag gatacaatgc tcctaacttc
     2461 actgtctcca tttttgtcca ctaaggaata taaaaaatag gcattaattc atttaattcg
     2521 gtcacaacac gttacctttt aaatcattat actgtatctc atacattatt atcaataaac
     2581 tattataaaa atgcaaaaaa tgctttatca atctattttg taattggtca taatatcatt
     2641 gaaatcatac cctgtatcga tttttcctat gaatctcgtc tatttgtgat tgacgaaaaa
     2701 gaggcaagac agacactgga atggtaattt tacccactat tttgctccaa ctatttgtaa
     2761 tcgtacccac ttttgaaata ccgagatgat cattttaatt gatatgctga ttcccaagca
     2821 aaaccccaag aaattaaatg ctctatcgca tctagcttct tgggttttgc ttatataaat
     2881 tccaacattt aaatttttta tgctgttcgg tctcagaaat gccgtttttg cttatatcac
     2941 aatatcaaga tgtcaaatta ttcgtgttgc cgatgacttt gattaatttt tttcaaattg
     3001 tttattaaga ctaatgctgt ctttttgcag ataccaatgt tcgaactttt taacattatc
     3061 atatgatcct gcaagtttta acttcttacc attagatgtt atcaaagtta taattaacct
     3121 tgcctttttc ccattaggat cttttatttt atgaattttc tgcaggtaat ctctcctaat
     3181 ggcagctatt tttacctcat cagtgctgat aaaccattga tcatccacat acatactgcc
     3241 tgttatgttg tgtttttcca tttcttccga gaacgaaaag tttaaggctc gttcttactt
     3301 ccaaagttga atgagtccat ggattggact tagtgtgaga attgagaaca acaataagaa
     3361 tccatatcct cccgcaaaca tccctaaggc tatactgtct ctccatccat aagtaggatt
     3421 agaagagaaa agagtcaccg tttgtaataa tatgaaaagg aataatccag cacaaacacc
     3481 aaagataaca actccaaaca ttgaattttt atacaatgac catttattta taggcttttc
     3541 tttcatttta cttcccccta ctgttctgtt cacacggaat gaattcaaag ttcataagcc
     3601 ctcctctttg aacatatgaa tacgacttgc taactatact ttaaaaaagc ttgttttaag
     3661 cggttatagg cgagttgtaa tctctattca tctcattagc aaataacttg ccgaaaagtc
     3721 tactgaaatt aaagcagata gtggaagaat tatttagcca ggatagacac tatttgtgaa
     3781 acacatgtct ttacttttga aattctatga tgaaaagcct tggaatacag tagctcttaa
     3841 ttggtaatac tttttccatt ataaataacc tcttttcatt ttatatttat cccctctaaa
     3901 aataatatct aatctaatat tttaaactta tatttccctc gctgtgctaa tagagcatta
     3961 ctaaataaat agaaactaga aaaaagcatt acgcctgcca gaataaacca attatttgta
     4021 t
//
LOCUS       DAFTHM010000159         3883 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFTHM010000159 DAFTHM010000000
VERSION     DAFTHM010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.160"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(456..881)
                     /locus_tag="L7C88_002698"
     CDS             complement(456..881)
                     /locus_tag="L7C88_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559479.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1255..2226
                     /locus_tag="L7C88_002699"
     CDS             1255..2226
                     /locus_tag="L7C88_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBP9559480.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2258..3655
                     /locus_tag="L7C88_002700"
     CDS             2258..3655
                     /locus_tag="L7C88_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBP9559481.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
BASE COUNT         1326 a          622 c          795 g         1140 t
ORIGIN      
        1 tactacgtga tgtagaataa gcctttctat cgtttggtta ttttatattc aaatatttga
       61 aataaataaa tctttactct ttgatttgta aactgaaatg atccactgtt tgttttactg
      121 atgaagcttg atcaaaggaa gaagctgagt ttgaagttca taaaaatcag ccatagtgag
      181 ttttgcttgg atttgtttat cttcttctac tttttacata attttgaaca ggataagatt
      241 caaatgtttt aaatgaatct ttgactagtt tgtgacagtt gtcgcatatg ctcaagcttc
      301 cttggtcatt aaattctgta tggatatttt tgttgttatt acatgtacaa taatcaggac
      361 tatcgatcat ccatttcgtc tcctttacaa tcatcttgct tctttactat agcagaaaag
      421 aaggggagaa acaaaagaag atccaacaga cggcactata gactgtagat gttgccatcc
      481 tcatccttca aacggtaatt accgattttt gtaaatatga ctgttgtttc ttttttattt
      541 tcttttcctg aaataatata ttcgtcatct ttggtagtga tcttgatatc tgtcagcact
      601 gttttttctt cagatgattc agaagaatca gttccttgtg tctgatacgt gcgtgtccat
      661 tccatttttt tatctgtaaa tgtcaactgt cccgcggata aatccatatc tttacgtact
      721 tttagcgtat atacactgtt ggtggtatct gctttttccg cttttaagac agaagaatcg
      781 gttgtttcgt ccgaggattg gtcagagccg ccaaacaaat cacagccagt caatgtcaaa
      841 agtcccgcag acaaaataaa tagtacgatt aatttcttca aaatacttcc cccatttgat
      901 aggataaaga aattatacca ttggaatgta aaacttcaaa cggatggaag agaaaaacgc
      961 acaaaacacc cacaaataga gtaaatttta gaataaaatt ttaaaaaggc aaaaaatccg
     1021 ccactttcag aaagcgtttt aaaaaagtgt tgcaatcttt taaaaaaatg ctatattaaa
     1081 aatgaaccgg ttcaaatact tgtttaagta taattaatag tgagaggaag ttgctctact
     1141 gaagacttta gttatatgga tattgatgac aagcaacact atgcaaagaa tgcggtcatc
     1201 ataatcgaac aacaagaaag agaaatcaaa tgtaactggc aggagtgaga atgtatggca
     1261 tcgatccgtg atgtggctaa gatggctggt gtttcagtgg gaacagtttc ccgttacttg
     1321 aatggtcagc aactgaagga aaagaacatg aaaaaaatag cagaagcgat ttcagcgttg
     1381 gactataaag aaaacatcat tgctaaaggg ttgaagaata atcgaagctt ctctattgga
     1441 cttttgataa acgggatttc cagccgtttt gggtcggaag ttgtctcagg gatcgaaaga
     1501 gtagctgaag aaaatgggta tagcttatta ttaagcgggt ttgccgatca gccagaaaaa
     1561 attgaacaaa aaattgaata cctgatgaag catgtgatcg atgggctgat tgtcttctta
     1621 tccgaagaag agtggtctgg atttgaaatg ctcacaaaaa tgagtattcc agttatcgca
     1681 ttgaattgtc cagaaggacc agcaggtatt gatacaatat tagtgaatga tcgagaaagt
     1741 gtagcaaaag tgatcgctca tcatggtgaa caaggacata aaaaaatcgg atttattgct
     1801 gccactcaaa cagactacgt agcaagagaa cgtttagcag gagccaaaga agcggtccaa
     1861 aatgatccat cgatccaatt agaggtcttt acaggagact attctagaaa aagcggctat
     1921 tacggggcaa aagcattatt agaaaaaggg gcaactgcta tttttgtcag caattacaat
     1981 atgtcgattg gtgccatcga atgtttcaat caagaaggtg tcagaatcgg gaaggatatt
     2041 gcgttcagtc actatgatta tttagataaa aacgatctga gtatccttcc gaaaatcacg
     2101 atcacgccac caacagataa aatcggggaa cgagcagcag aacagctgtt aaaacgaatc
     2161 aaaaaagaag aggaagaaaa tgaaaaagtg attgtgatgg aaaatatcat acatggaatc
     2221 aactaaaacg aactaaaaaa gaaaaagagg tgctttgatg aaaaaatatc aatttccagc
     2281 aaatttttgg tggggttctg cagcaagtgg cccacaaaca gaaggaagga tttcaggcga
     2341 tggaaaagga gagaacattt ttgattattg gtacaaaaaa gaaccgcaaa agttctttga
     2401 tcaagtagga cctgaaaaaa cctcgcaagt ttatacgaag tatcaagagg atgtacagtt
     2461 gatgaaacag actgggcata attcatttcg aacatctatc caatggagcc gtttgatacc
     2521 tgatgaatct ggaacaatca acgaagaagc cgttcgtttc tatcatcgtt attttgatga
     2581 gttgattgaa aacggtatcg aaccctttgt gaatctgtat catttcgata tgccgatgta
     2641 tctgcaagaa aaaggcggat ggttgaaccg agaaacggtt gaagcctatg aaaaatatgc
     2701 caaaagttgt tttgaattgt ttggttcgaa agtaaaaaaa tggtttactc ataatgaacc
     2761 aatcgttcca gtcgaagcag gttatttata tcgatggcat tatccagaag agtcagatat
     2821 gaaaaaagcg atccaagttg gctatcatga agcgttggct tcagcgttag ccatcaaatc
     2881 ttaccatgaa atggagcaag gtggtgttat tggtatcatc ttgaatctga caccaagcta
     2941 tccaagagac gaatcaaacc ctgaagatgt taaagcagcg caaatagcag atgcgttctt
     3001 caatcgttca ttccttgatc cagctgtaaa aggcgagttt ccaagtgaat tgattgagat
     3061 agtaaaagaa cttgatctca tgcctgtgat ccatgcagag gatttgacgg ttatcaaaga
     3121 aaatacagta gatcttttag gtatcaatta ttaccagcca cgccgggtaa aagcaaaaga
     3181 aacaccaatc gatactaaaa acggtccaat gcctgaggat tatttcgaca attatgaaat
     3241 gcctggtcgt aaaatgaatc cttatcgcgg atgggagatc tatgaacaag gaatctatga
     3301 tattttgatc aatgtacgag atcattatgg aaatatcgac tgctttattt ctgaaaacgg
     3361 tatgggtgta gaaaacgaag cacgatttat caaagaagat ggcatgatcc acgatgatta
     3421 tcggatcgaa tttgtccaat ctcatctgaa atatgtccat caagccattc aagaaggtgc
     3481 caattgttta ggctatcata tgtggacatg tatggataac tggtcgtgga ccaatgcata
     3541 taagaatcga tatggcttta tttcagtaga cttagcacaa gatggaaaaa gaacaatcaa
     3601 aaaatcgggt cattggttca aagacgtatc agataaaaac ggatttgagg cttaagaaag
     3661 aatagttgag agcaaatgcg tgaaattctc cattcttacc attttgtgaa aaagaagttc
     3721 aattatttac gatctttttc aacttttttg tctttctatt tcattttttg tatataatag
     3781 aatagtcaaa attaaatagg agtggaggaa agcatgagga aaaaaagacc gtttcttctc
     3841 ttttggttat tcggtttttt cttactgctt attttatccg cag
//
LOCUS       DAFTHM010000160         3759 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFTHM010000160 DAFTHM010000000
VERSION     DAFTHM010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.161"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            302..793
                     /gene="nrdR"
                     /locus_tag="L7C88_002701"
     CDS             302..793
                     /gene="nrdR"
                     /locus_tag="L7C88_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBP9559482.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            816..2189
                     /locus_tag="L7C88_002702"
     CDS             816..2189
                     /locus_tag="L7C88_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBP9559483.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            2189..3115
                     /gene="dnaI"
                     /locus_tag="L7C88_002703"
     CDS             2189..3115
                     /gene="dnaI"
                     /locus_tag="L7C88_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBP9559484.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            3244..3684
                     /locus_tag="L7C88_002704"
     CDS             3244..3684
                     /locus_tag="L7C88_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBP9559485.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
BASE COUNT         1332 a          635 c          828 g          964 t
ORIGIN      
        1 aatcgagatg tgacttgaag cagatgagaa ggtgttcatc tgcttcaagt tttttgtgct
       61 agatgactaa atcagctttt gtgtaagtta tttctcagta atcaaggtga tcagtattgg
      121 aaaattgaaa tttagtaagg acaggggaca caattacgca tgaaagtaga aaaaattgtt
      181 cttatatccg tgttttttgg gtaggacagt cgcgtttgtg atttgtttcg tgttataata
      241 caactagttg taaagaaaga cacatccttt atataaaatg cgatgcaaga ggtgagacaa
      301 aatgagatgt cccagatgtc aacataataa ttcacgagta atcgacagcc gtcaagcaga
      361 tgatggacgt gcgatccgtc gccgtcgcga atgtgagaat tgttcgttcc gattcactac
      421 atttgaacga attgaagctg ctccgttatt agtaatcaag aaaaacgggg aacgcgaaga
      481 gttcaatcgc gataaaattt taagaggact catccgttca gcagaaaaaa gacctgtagc
      541 tatggaacaa atggaacaaa tcgtcaacca tgtcgaaaac cgcgtacgca gtctcggaga
      601 aaacgaagta tcgacgaatc taattggtga atatgtgatg gaagatttag ttgatttaga
      661 cgaaatcgct tatattcgtt ttgcaagtgt ttatcgccag ttcaaagata tgtctgtttt
      721 cttaaaagag ttgcaagata tcgtggataa agcaaaagaa aataataaag agaataataa
      781 agaaaacaat taagaaacaa aaaggaggca tttccttgga aaatgcttgg aaagagcttc
      841 aaccaaaaaa tatttaccaa ggaagaaaag cggctccgct gagagaagac agcaagaacg
      901 ccttgctgta tctttatcag ccactaatcg gcggagaagc cttgagtatc tatttcaccc
      961 tgttatcaga aatctctcaa gaatctggca aaggtcctga agggatgcat gcagatctgc
     1021 ttagtagtct aggctgcggt atcccgcaat tttatgatgc aagaaaaaag ctagaaggaa
     1081 tcggcttact ggatgtttat tttaaagaag atagtgatct gggacctcgt tttatttatg
     1141 agctgttaga accactcatt cctaaagcat ttttcaaaga ctctgttctg gcttttcttc
     1201 ttctggaaaa agttggtgaa cgacgattcc agaagcttac ccaattcttt gaacctaaaa
     1261 ggcatacagc agagggatat caaaaaatca caaaaaaatt tttagatgtt tatcgcttca
     1321 atgaagcagt gtacgctgct aatcaagaaa acatcgaatc gctgaataaa tcttttgaag
     1381 aatctgaatc agtagcatta cttgaagcag attcgacatt cgattggcag tttttgaatg
     1441 attggctggc aaaaaaacat attgcaagtc ttgatgatcc aatcatcaaa caagtcgaca
     1501 tgtatcatca gctttacggt ttcgatgaat tgacacttgg cgaactgatc agtcaatctt
     1561 atgactttag tgaacaaaaa gtatctgaaa aagaactgca aaaagccatt ttggcaatgc
     1621 agagacgtcc ggtgaagcaa acaaaagaaa cagttgcggt ttctgaaaac agtaatgaac
     1681 cctcgtcaaa cgaacatttg acaaacgcag cgcttcagct gataaaagaa gcacagagca
     1741 ttccaccgat gaaatatctg gaagcaatca agtcagaaaa aggcggatat gtttctaaac
     1801 aagaaaactg gttactgcaa gatcttgttt ctcaatcagg tctttccagt agcgtgatca
     1861 atgttttgct gaattatgta ctagtgatca agaataatgc tagcttaaat gccagttatg
     1921 taaatacagt ggcaaatgaa tgggcacaaa agaaaatcgc cacagcagaa gaagcgatcc
     1981 agcacattcg gcaaataagt aatcaagcaa aacaatcaaa acaaaagaag caaacaaatt
     2041 atcaaactgg caagcgaaat gttcgacggg aaaagcttcc tgattgggtc aaccagccaa
     2101 aagatgaaaa acagatcagc agcgagaaaa aagcagagat tgaccgccgt tttaaagaat
     2161 acctggcaaa aaaggagggt gatatctagt ggaagacgta ggcaaagaat tgaagaggat
     2221 catcagcaaa cgcaattatc aagaaaagta tgctgaaatg atcgctgaag tcttaaatga
     2281 tgcggatgtt caagcttttc taagcgcaca ccaagaagaa ttgacacaag cggatattga
     2341 aaaaagttac gctaaattgt atgaattcgt gcaagaaaag cgtaaatatc aaaaaaacga
     2401 tccaacgatg atcgctcccg gctatgagcc gaagctgacg ttgaattttc attatgtgga
     2461 tgtcacttat gtaccaacgg aagcattgtt agcacggcaa agacaagaag aaatcagaag
     2521 ccgagtaaaa gcaatggata tgccaaaaga tattcaatcg gcttcttttg aaaactttga
     2581 acgtacagat ggacgaggat atgcgagctt agaagcccta gattttgtag agaaatatac
     2641 tgctgatcca aaagggtatc ataaaggact gtatctagta ggaagttttg gtattggaaa
     2701 aacatattta ttaggagcaa cagcgagaga attagcgatt gctggattca ccacgacgct
     2761 agtccatttt ccgacatttg ccgttgagat gaaacaggca atcggaaaag atcaagtggc
     2821 agaaaagtta gatgcagtga aacgttcacc tattttgatg atcgatgaca ttggtgcaga
     2881 tgcgatgagt agttggatac gagacgaagt attcggtgtt atccttcaat atcggatgca
     2941 ggaacagtta ccaaccttct tctcatcgaa ttttacaatg gatgaattgg aacagcattt
     3001 gtccgtcact caacgtggag atgaagagcc gctaaaagcg aaacggataa tggaacgcat
     3061 acgttatttg acaaaagaaa tcgaaatgac tggtcgcaac cgacgcaatg gttgaacagt
     3121 tgacaagtcc aactgacatt tgacctagta gtaaaagcag gtcagcgaat cattatatgg
     3181 acagaaatga ccggagacaa tcaccgcaac aagtaatgca gaaacttaaa cggaggattt
     3241 tttatgaggg ctattttttc tagtatatct gtagttggtc tattttttct tttagcaggc
     3301 tgcggtagcg cagatagcaa cacaggttct gttgattcga ttgatgcggg tcaaacagta
     3361 aaaacaagca gtacgaaaac ggagagacaa agcatatttg tcggaacgat tgaaagtatt
     3421 actcaagtag aagcagaaga agaaacgctt cagttgaaac tcgtcgatgt catggccaaa
     3481 gaagatccag cgaatatggg aacgtcattc agcaatgacg gagtgatctt aaatgctact
     3541 gctgaaaaaa taagcgtgga cataaatgaa ttgaaaatcg gtgacaaagt ccaatttaca
     3601 ttagttgaga tgccgatcat gacgatgtct atcccaccgc aagttcctgg agattcgatt
     3661 attgatgttt cattgaacaa ataaccaata acattttttc aaaaataaga aaatgttgtt
     3721 ttatagaacg aaaaggtata ttttttaagg agatatggg
//
LOCUS       DAFTHM010000161         3716 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFTHM010000161 DAFTHM010000000
VERSION     DAFTHM010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.162"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            268..1155
                     /locus_tag="L7C88_002705"
     CDS             268..1155
                     /locus_tag="L7C88_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBP9559486.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            1152..2321
                     /locus_tag="L7C88_002706"
     CDS             1152..2321
                     /locus_tag="L7C88_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559487.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            2345..3700
                     /locus_tag="L7C88_002707"
     CDS             2345..3700
                     /locus_tag="L7C88_002707"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBP9559488.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
BASE COUNT         1227 a          672 c          869 g          948 t
ORIGIN      
        1 aagagctgct agaagagctg ccagagcaga acgacgtaaa aaaatggaac aagctacaaa
       61 agaaaaaaag gaaaaataac agaaaaaata taatgaataa ttctctgaag tttaaaaata
      121 tttattgcag agaaaaataa aacgcatact tgcaattttc ttgaaaatta tgcgtttttc
      181 tcaagaaaaa tacgagcata tcagcctcta aaattaaaac atatgatata ctagagagga
      241 aatctcaaaa gagaagagag gctttttatg tcatttcaaa tcggggaact ttttaatttg
      301 gactattggc agcaaatgtt ttccggtgac ttgttctctc tgaatttttt ggtgaacata
      361 cttgatattc tggttgtctg gtatcttgta tacaaactga tccaactgct gcgaggcaca
      421 aaagcgattc agcttctgaa aggtgtagct atttttattg ttatccgaat cgtagcggaa
      481 atcattggtc tgcacacctt gtcttggctg atgaaccaag tcattacgta cggggtgata
      541 gctgctatcg tgatttttca gccggaaatc cggagaggac tggaacatct tggacgcagt
      601 tcgcttttca aacaatcaaa aagcgaacag caggaagatg agaagatgat cttgtctttt
      661 gacaaagcca tccaatatat gtccaagcga aaaatcggtg cgttgatcac tatcgaacgt
      721 catactggat tagatgagta tattgagaca gggattgctt tagatgcaga tatcactggg
      781 gagctgctga tcaatatctt tattcctaat acaccgctgc atgacggtgc agttattgta
      841 aaagaaggaa agatcgcagt agcaagcgcc tatcttcctc tatcagaaag tatgttgatc
      901 cctaaagaat tcgggactcg acaccgggca gctgtcggta taagcgaagt cagtgacgcg
      961 attaccatcg ttgtctctga agaaaccggg gacgtcagca tcacgttaga taatgaactg
     1021 atggctggct tatcccagca agaatatttg gcaatcttgc gtagagaact aattgctgaa
     1081 gagaaaacaa aaaacaagaa aaacgtgatt caatctttcc tagacggtat gactaaggga
     1141 ggggatcgca aatgatctca aaagagaaac ggacaagcat tctttacagt tttattgcat
     1201 tgctgttcag tattgcgctg tacttcaatg caaatggcca gtccgttcca aatacgcttt
     1261 ctggaaatga agcgtataat caaacagtta cgggggtgcc gatcaagatt tcttatgatt
     1321 caaagcgcta ctatatccat ggatatgaaa atgcagtgac tgtcaaactt tccagtgcaa
     1381 accgagttca gttgaatgca gaggcaaacg aagatacacg gatgttccgc gtcacagcag
     1441 atatcactaa gctgggcgaa ggaacacatg aagttccgct aaaaattcaa aatttgagca
     1501 gtgctgtcac agcaaagatc gaaccatcga ctattacagt aacggttgag aaaaaggtaa
     1561 taaaagattt cgatgtggaa acgttgattc cttcaacgtt cacaccatct ggatatgaac
     1621 ttgatgatac ttccgttagt cctaaaaaag tctctatcac tacaggtgac aaaacattgg
     1681 cagaaatcaa acgagtagta gctgatgtgg acgcttcgat ggtcacagat gatgggatta
     1741 atagtgaggt cccaatacag gcgctgaatg cagcagggga agtattaagt atcgtctctg
     1801 atccagtgca agtaacagtg agagctgatt cgatcaagcc aagcaagtcg gtacgacttt
     1861 atgggataca gcaaggaaca ccagctgccg gggtagaaag ctatgatttc agtttttcaa
     1921 aactggaagc agaagtaagc ggctctagcg atttgcttgc atcgatcggt gacagtattg
     1981 ctgtaccgat caatgtctca ggtatcaatc atcgaacaac tcgtaaaatt gaaataccag
     2041 tagaagaggg gttaagtatc aagcccgaat cagttagtgt ggagattaca cccgtgttgc
     2101 aaacgtcaag cagtagctct gcttcgacga gcagtcggac acaagaaaat acaagtacga
     2161 gtagaagtat ttcatctgct gattcaggaa cggaaccatc gacaacaacc atttcttcca
     2221 gttcggaatc tgggacaagc agctcgacca caagtacaga agaaacatca gaaacaagcg
     2281 aatcaacaca aatgagcaga acaaattcct cagaaaatta agttaaagga gtaattttac
     2341 aactatgggt aaatattttg gaacagacgg cgtacgcggt gaagccaaca aggaacttac
     2401 gccagaactt gcatttaagc tgggacggtg cggaggttat gtcctaagcc agcatgaaga
     2461 agaaggaaaa cgcccacgcg tgttagtagg gcgggataca agaatctcag gtcaaatgtt
     2521 agaagaagcg ctgatttcag gacttttatc ggtgggtatc gaagtgttcc agctaggtgt
     2581 gatctctaca ccaggtgttg cttatctgac acgtttgcaa aaagcaagcg caggggtcat
     2641 gatttctgct tctcataatc cagcacaaga taatggaatc aaatttttcg gtgcagatgg
     2701 ttttaaacta gtagatgacc aagagctaga aattgaagca ttattagatg ctgaagtgga
     2761 tgaattgcct cgtccatcag ctgaaggatt gggaactgta gaagaatttc cagaaggctt
     2821 attgaaatat tctcaattcc ttgtacaaac gatcaacggt gacctttccg gtttgaccat
     2881 ttgtgtcgat gcagcaaacg gagcaacttc aacaagtgtt aatcgtttgt ttgccgatct
     2941 tgaaacagat ttttatacaa tgggcacaaa tccagacggg ttaaatatca atgacggcgt
     3001 aggctctacc catccagaac gtttagctga gatggtcgtt gaaaaaggag cagatgctgg
     3061 actagctttc gatggcgatg gcgatcgtat tattgcggtg gatgaacttg gaaacattgt
     3121 cgacggtgat aaaatcatgt ttatctgtgc taaatacttg gcagaaaaaa atcgattgaa
     3181 aaaagatacg atcgttacga ctgtcatgag taacttagga ttccacaaag cggtggaagg
     3241 aatcggtttg aaagatgtcg ttacacaagt tggtgatcgt tacgttgtag aagaaatgcg
     3301 caaaaacgat tataactttg gcggcgagca gtctgggcac atgattttct tagattttaa
     3361 cacaactgga gatgggatgc tttcaggaat tcagttactg aatatcatga aacagacagg
     3421 taagaaatta tcagagcttg cagcagaggt aacaatctat ccgcaaaaat tagtgaatat
     3481 ccgcgtaagt gataaaaacg gtgcgatgga tgttccggca atcaaaaaag tgattgaaga
     3541 ggcagaagct gaaatgggat cagaaggaag aatcctagtt cgtccttccg gtacagaacc
     3601 attacttcga gtgatggcag aagcgcctac tgatgagaaa gttaattact atgtcgataa
     3661 aatcgcggca gtagtcaaag aagaaatcgg actggattaa gagatatttt cataaa
//
LOCUS       DAFTHM010000162         3713 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFTHM010000162 DAFTHM010000000
VERSION     DAFTHM010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.163"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="L7C88_002708"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="L7C88_002708"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBP9559489.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="L7C88_002709"
     CDS             complement(2260..2511)
                     /locus_tag="L7C88_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBP9559490.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="L7C88_002710"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="L7C88_002710"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBP9559491.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="L7C88_002711"
     CDS             3461..3679
                     /locus_tag="L7C88_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559492.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
BASE COUNT         1026 a          796 c          688 g         1203 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca aga
//
LOCUS       DAFTHM010000163         3621 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFTHM010000163 DAFTHM010000000
VERSION     DAFTHM010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.166"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            75..470
                     /locus_tag="L7C88_002712"
                     /pseudo
     CDS             75..470
                     /locus_tag="L7C88_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(465..683)
                     /locus_tag="L7C88_002713"
     CDS             complement(465..683)
                     /locus_tag="L7C88_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559493.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWKS"
     gene            790..1104
                     /locus_tag="L7C88_002714"
     CDS             790..1104
                     /locus_tag="L7C88_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9559494.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1208..2386
                     /locus_tag="L7C88_002715"
     CDS             1208..2386
                     /locus_tag="L7C88_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBP9559495.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            2789..3082
                     /locus_tag="L7C88_002716"
     CDS             2789..3082
                     /locus_tag="L7C88_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBP9559496.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         1233 a          530 c          711 g         1147 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcttcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga tttccatatt
      481 tcgattttgg ttggcatatt tttcatgcca aattctgtga ttttaatagc atcggcaaga
      541 tttaattttt cttcagctct ctctccactt ttaagttttt ttactgtact caagttgatt
      601 cctgttccga atgctattgc attagccgta gatttttcaa gaatttcttt aattattttt
      661 atgtctgcaa ttccttgttt catattaaaa attcctcttt tctagtccgt tttgatggag
      721 tactggagtg tttttttaca attttaaggg gtaccgtggt ggtcgttttg attttgagag
      781 agaagggtga tggagttgga agttaaaaca aatgttaatt ctctggaaat agagttctat
      841 tcaattttac aaaaaaaact ggaagattac acggaaaaat tgcttgcagt cagtcattta
      901 cctctggtat taacaaatac tgatttaaag cgactatttc agataagtga tagtacactg
      961 aaccgtttag taaaacttgg tgagtttcct ccctgttggt acgggattcg aggacactat
     1021 tttcgtgatg atgttttaga atggatgaga aagagtgatt cgaatgacta tcgagaaaaa
     1081 ttgcgactac ttcgatcttt ataagttaca ttttctttct aagatgcggt acaatgatga
     1141 catagataga aagatttcca aagggtttct gcttgttggg ttccttcaaa ataggaggaa
     1201 tcaataaatg gaaaaaacag atcgattcaa gaagcaaatc agttctactg gtaggatcac
     1261 atggtacttt caagcatatc gaacaacaag acgtggcttt aattcaaaac gtgaggcgca
     1321 actcgcttat ctggaaatgg agaaacaaca aaggcttaag aaaaaaattg ttgcaagcaa
     1381 tgacaagttt agtgttgtag gtgagcaatg gttccaatat taccgttcgt taaatgaaca
     1441 aaaggaaata acctatgata agcgagagga acaattaaaa attattgttc gatggattgg
     1501 tgataaaaag ttgtctgatt tgacaccaga gtgccttcaa gaattgcttt ttaccttaaa
     1561 ggaatgtggc gttaatggaa caaatgttgg ctatgccaaa aatagtttac aatcacttat
     1621 tcaagttcta aatatgattt ttaaatattg tcaaagaaag aatttgataa gtgaaaatcc
     1681 aatgaagtct gtgagaatgc caaaatatca gttaacggta actgatttaa aagaagccat
     1741 aaataatatt gaggacaagt ttcttactgt cgatgaattg agaacttttt tgaattatgg
     1801 cattgttcat gaggaattac cgatgtctgt acttttccat gttctatttt acactggctg
     1861 ccgagtcagc gaggcgcttg ctctacagcc tggagatata gatttcaaaa gaaatgaaat
     1921 tctgttctat aagcaaacgg cagttaaagg taagagtaag gattttcgaa ttgaaactac
     1981 taagacagtt agttctgcta gacgagttct agtaactcct ctagttatgg aaaagctaca
     2041 acagttgatt aaggctttgg gtgagatgag gcaacattac aggtttatta tagaagaaac
     2101 atatttgttt gtgtatcttg attctagtaa acgtggtgtt ccttatcgtc gagagtatgt
     2161 aaatgatcac gtcaaacggt gcgtgaatcg ctcaggaatt aataagccat ttcatactca
     2221 tttagctcgt catacaatgg caagcttagt agcggaacac tgtagctggg aagtcttgaa
     2281 agatcgctta ggccatactg accaaacaac ttcgaaaatt tatcgccact taacgtcaaa
     2341 tgaaaaggta aaacctctga ttgcttttag ttctttagag agttaaaaaa acggtgaaag
     2401 cactggtatt acaggattct tgaaaaacga ttttttaaca aattagtcaa tatgtagtca
     2461 gaggtaataa aaatcctttt atatcaatac tttaacgact tttcacaagt atcaaagaaa
     2521 tccgtcgtta atcattgtta tcagactgag aaagaaccct tggtattcaa gggttctttt
     2581 ttcttagcat gtaatttgaa caccctgatc cagttttttc tttaattatt ggtaggggag
     2641 aataatggat tagaataaat ctacctataa gtagtagtaa aaaaaagagc actatgataa
     2701 tatctttctt aagagtaacc gctttaataa aaaatccaga atattctaac ataaatggag
     2761 tattcttaga atcaaaagga gaaagaagat ggtttatact tatacggagc aagaaaagat
     2821 gaaagtttta gacacattca tgaatgatgg aaaagtaaaa caagtaccaa gttcaacaaa
     2881 aaagaaatac atcctattga aagaagtctt gaaacgcttt gaccatggag tgacttatac
     2941 agaaacagag gttaattcga tactgctgaa cgtattttct agtggcgatt atgtcgaaca
     3001 aagacgttat ctaatcacat ttggcttttt caaaagaagt tcagacggtc gggcatatca
     3061 gatgatggga attgaaaatt agaagtttta atttatactc attgaaaaaa gttcaagtat
     3121 gcgatattgg ttctacaccg catacttgaa ctttttttgt catctgtatc tataatacaa
     3181 agccaagaac gttattcaaa atatggatag ctatgataaa agctaatgag cgattcgcag
     3241 ttaaataagc aatcgtcagt aaaatcgttc caggagcgta catgaaaaaa tcaattggat
     3301 gcgttacatg aataaagata attctctttt atttgtacga ataaatacca aaacgtacct
     3361 cctaaaatta gattttggac agatgccctt taaaaagata acaagatttc gttcttgaaa
     3421 caatatatat gcttttattc caatgaggtt gtgaaaacag tattttgtcc tgagcgttag
     3481 aaaattgaaa atggggaata gcaactcgta ctttaccatt ttttaagtga atacaagatc
     3541 agctaattga acaccgttta ttcgtgatga gggacacaac actgcagtcg acacatttct
     3601 cttttatgtt caaagataac a
//
LOCUS       DAFTHM010000164         3602 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFTHM010000164 DAFTHM010000000
VERSION     DAFTHM010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.167"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            174..518
                     /locus_tag="L7C88_002717"
     CDS             174..518
                     /locus_tag="L7C88_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBP9559497.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            519..938
                     /locus_tag="L7C88_002718"
     CDS             519..938
                     /locus_tag="L7C88_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBP9559498.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1030..1380)
                     /locus_tag="L7C88_002719"
     CDS             complement(1030..1380)
                     /locus_tag="L7C88_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559499.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1346..2566)
                     /locus_tag="L7C88_002720"
     CDS             complement(1346..2566)
                     /locus_tag="L7C88_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBP9559500.1"
                     /translation="MLSNTPTDNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILT
                     LLSVLLAYRHKVILNGPLFASILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQ
                     YIMIGLFGSALSPVVSYITFGMRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGF
                     TLYNIGFTSGLIAMTFTAVLRLFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFY
                     YNSFRLLGIREIFDSSGKLTTDFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPV
                     IGAILSAVGFSAFGCHLKNSFPILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPIS
                     GFYGSFYGVIAGVLHIALVHNVSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKE
                     KKTLGKRIIKKNHR"
     gene            2932..3498
                     /locus_tag="L7C88_002721"
     CDS             2932..3498
                     /locus_tag="L7C88_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBP9559501.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
BASE COUNT         1342 a          610 c          691 g          959 t
ORIGIN      
        1 aaataaaaaa agcgttagca actatgctta aaaagcatat cgactgaata aactaagcat
       61 tggacaggct gaaagactac atttaaaatg aaatgcgaag aaacaataga aaataaagtt
      121 gccttagaac catagttgaa tcacctaaca gtcgtgaagg gagaataaga gaaatggcag
      181 aaaaacaaac cgcaggacga gatcaattag gagattttgc accaaaattt gcagaattga
      241 atgatgatgt tttatttgga caagtatggt ccagagaaga attatctgct catcagcgta
      301 gtatcatcac catatctgca ttaatttcag gaggaaattt tgaacaattg ccagctcatc
      361 tgaagattgg caagcaaaat ggcattacta gtgaagaaat agcagaaatc attacccatt
      421 tagcttttta tgtaggatgg ccaaaagctt ggtcagcttt tagtttagca aaagaaatct
      481 atttagaaga aaatagcgaa gataagaaag aggcgtaaat gacgacaaaa cacgaagaaa
      541 tacacaatgg cgtgattttt ccagcaggtg aaaaaaacga agcttacgct caagtattta
      601 ccgggcaaag ctatctgaat atgttagtga atgatcccga agtttctgtt ggtgtaggta
      661 atgtaatttt tgaaccaggt tgtcgcaatc actggcatgt ccataaagac ggctatcaaa
      721 tcttacttgt gaccggagga gaaggctggt atcaggaaga aggaaagcca gcaagacgat
      781 taatggctgg agatgtcgtc gtaacgcaca aagggattaa acattggcat ggtgcgacaa
      841 aagacagttg gtttgaacat ttggcgatca ctgctggtaa ttcagagttt ttagaacctg
      901 taacagatga agtgtatgaa ggattggaaa atcaataatg tcaagcttga acagctcctg
      961 aaagtagatt ttaatcgaac tttcaggagc tgcttttttg attcagtctt ttataaatag
     1021 aaaatagggt taataatagg aatgagaagc acgtcgaaag atcttaatat tgataatcgg
     1081 ctgggcatac atgatttcca cgtcatcaat caaactacct aacagatgat aatcttcccg
     1141 atcatgtcgg ggattaccta atagttcttg atagtagatt tccatactag ggtcccgagg
     1201 attgttcagc aaatcagcaa gtacatctaa atcttctggc tgagtttctg ccgtaccctg
     1261 tatctctatg aaaagccctt cctcagcaaa ttctactcca atacgtattt cagttatttc
     1321 atgggaatat aaataagtaa gaagctcatc gatgattctt tttgataatt ctttttccaa
     1381 gtgtcttttt ttcctttctg acagcggtaa agttatctag tatcggtaca aggatacctg
     1441 caacgaaacc agttgaaaaa ccactgttat atagatttag tcctccgtgc aaagtgctga
     1501 cgttatggac aagagcaata tgtagtacac cagctattac accgtaaaaa ctgccgtaaa
     1561 aaccgcttat gggcgcgaga cctgtcccaa acacagctgc aacaagcatg ccagtactgg
     1621 tgatctcatg aaaagttcca aacaaagaag caataaatat tccgactagt atcggaaaac
     1681 tgttttttaa atgacaacca aaagcactga aacccaccgc agataaaata gcaccgatga
     1741 caggtccatt taactgaccg ccaaccagca aaacataaga agacagcatc agaccaacta
     1801 agcctatgtt gatcaaagta gcaccaatac cagaattagc aatgaaatca gttgtcaatt
     1861 ttccagatga atcgaaaatt tctcgaatcc ccaaaagccg aaaggaatta taatagaaac
     1921 caattccgac tgtcagcgaa aaaaagccaa aaataatcca aatgagagga aagtgatatt
     1981 cattgaaaac caatgtattt tcgacgattg aatagctgaa taacctcaaa acagcagtaa
     2041 aagtcatcgc aatcaaccca gaggtgaatc caatattata aagtgtgaat ccacgatgga
     2101 aaactaaagt ttgagcagct aagggcggaa gaagtagacc aattgctatg ccagctaaat
     2161 tccccaataa aatacctatc agtaaaggaa aacgcatacc aaaagtgata taactaacga
     2221 ccggtgataa tgcgctacca aacagtccga tcatgatgta ctgagaaaaa ggtttattga
     2281 caaatacagc gtatagatac acacctaaaa tgattgagat agaattataa aggtttttgc
     2341 caaaaaaaga gaaaccggta actgttagaa tcgaagcaaa taagggaccg tttaaaatca
     2401 ccttgtgccg ataagctaaa agcacagaaa gtaaggtcaa aatccctaca tttatgaatg
     2461 cgcttccgaa accgcctaaa gcaaaataat ctgtcaaaag attgcttggc gaggtaagaa
     2521 tagttagcaa tccactccaa ttatcagtag gagtattaga aagcaagcca ataaaaagaa
     2581 aaaaacacct gtaaaaccaa gataaaaata ctttcttttc tgtgaaacga ttcgtttttg
     2641 aggatgaata taaataacgt cagtttcgtt ttccattaca caccttcttt ttcattttct
     2701 ttaactataa cttgaaatga aagatttgga caactatcat ttaggtcaaa actaaaaatg
     2761 taagggaacc cattgaattt aaccaaattt ttttaatttt gcaaaaaaaa gttaaagaag
     2821 actgaaaaaa aatttaaaat ataacgtttt gagtaaaatg tttgcaaaaa atgctaaaaa
     2881 tagggtacaa taaaacaaca tatactgcag taaagaagtg ggggagtttt aatgagaaga
     2941 aaagtctata ccaaggatca aattctaaaa gctgcttatg atgttgttgc aaaggaaggg
     3001 tttaaaggat ttactgcgag aaatattgct aaaaagatgg ggatttcgac acagccgatt
     3061 tatctggaat tcaaaaacat ggaagattta aaaaatacgt tgctggattc tatctttgaa
     3121 caactaaaag aagatgtttt ccctattgaa cgtactggtg ataaaatcat tgatctcggt
     3181 ttgaactata tctactttgc aaaaaagcat catagtcttt acatggcatt gtacattgat
     3241 gaacatgggg acggaaagaa aatgcatgat ttttcataca attatttccg tgaaatagtt
     3301 aaagaagatg aaagatacaa tcaattatcg gatgaatatg tcgatgctct gcatactggt
     3361 acatgggtag cagtgactgg cttagcgtca ttgatgtcat caaacatcat gcatccaaca
     3421 gaagaacaaa tcattgcact gatcaaacgg acaattgact cgattttagc attagataat
     3481 cctgaaataa tcagatagtg ttctatcagt atgaatttga tcggtaagtc cgttggctgc
     3541 aaactgtcaa tggacttttt tgctaaaaaa agcgatttct gttatttatc tattagaaat
     3601 ag
//
LOCUS       DAFTHM010000165         3417 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFTHM010000165 DAFTHM010000000
VERSION     DAFTHM010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.168"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..2232)
                     /locus_tag="L7C88_002722"
     CDS             complement(<1..2232)
                     /locus_tag="L7C88_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559502.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="L7C88_002723"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="L7C88_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          946 a          759 c          545 g         1167 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg aatccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaaac attcgttaca tatttgtgaa tttttcc
//
LOCUS       DAFTHM010000166         3201 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFTHM010000166 DAFTHM010000000
VERSION     DAFTHM010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.169"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(230..742)
                     /locus_tag="L7C88_002724"
     CDS             complement(230..742)
                     /locus_tag="L7C88_002724"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBP9559503.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(756..3053)
                     /gene="recJ"
                     /locus_tag="L7C88_002725"
     CDS             complement(756..3053)
                     /gene="recJ"
                     /locus_tag="L7C88_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBP9559504.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
BASE COUNT          889 a          734 c          550 g         1028 t
ORIGIN      
        1 aaaaatcggt cacatccttt ttttcgaata aacggtgttc taaagccagt ttttcggtat
       61 taagtcaaat tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat
      121 ttataaaaaa atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt
      181 taaaatcgct tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca
      241 ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga
      301 tcaaaaatgc gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt
      361 tgattgttcc tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa
      421 tggcatcctt atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga
      481 tggtttctcg aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat
      541 aagcaacagg acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc
      601 gtttttcttt tgcataattt acgatttgtt tagtagcttc ccgataagcg tcaccatctg
      661 ccatcagtgg ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg
      721 caatataatc ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg
      781 gtaggaatat cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgtcgctgg
      841 tataatctgc tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg
      901 ttctctattg taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt
      961 tcagggatac gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct
     1021 tgagaatgga tcaatttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa
     1081 taggcctcat caggtgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa
     1141 acttctttca gatccgctaa atcatctgga caatccataa caactagaga gtttggtttt
     1201 cttttttcaa ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg
     1261 ataatctcag gcacgaattt caacgtcgaa gaatcaaatg ctaaataaag gctaccttcc
     1321 gacgttcggc tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc
     1381 acagaaaaat cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa
     1441 agctttccta ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca
     1501 aaagcgaccg catcaagctg actcgatgca tcggaaagga caaatttcag atgctgttgg
     1561 tttgctccga ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa
     1621 ggattatccg taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact
     1681 tcatttggca gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga
     1741 tgatcgacta tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc
     1801 gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca
     1861 agcatttcaa aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct
     1921 tcttttaaag taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca
     1981 atgcccaaaa cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta
     2041 ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg
     2101 atctcattca atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac
     2161 gagacggcag gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa
     2221 aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc
     2281 tgaagtccta tccgttctga atgatgaatg gcatcgattc ctaatgaaac aaggattcga
     2341 ttctcatcag tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat
     2401 tctgcaggcg gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc
     2461 aaatctggaa atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct
     2521 ggtaaattct caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga
     2581 gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt
     2641 ccttcttcga tcttttcttg gtataccgat tggtttggtc catacccatg ctcaaatcga
     2701 tttggcagga atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt
     2761 gcactggtga tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt
     2821 acagcttctt ggattcggct gattgcttta tccatatcgt gtatcagata cggatcatgt
     2881 aattcttgtt cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt
     2941 tgccacagta acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag
     3001 gattcagaag gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca
     3061 ctcctaactt agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa
     3121 aaacagatca gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt
     3181 atgaaatatc cctattagtc a
//
LOCUS       DAFTHM010000167         3128 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFTHM010000167 DAFTHM010000000
VERSION     DAFTHM010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.170"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            103..1347
                     /locus_tag="L7C88_002726"
                     /pseudo
     CDS             103..1347
                     /locus_tag="L7C88_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            1360..1992
                     /locus_tag="L7C88_002727"
     CDS             1360..1992
                     /locus_tag="L7C88_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBP9559505.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            2197..2424
                     /locus_tag="L7C88_002728"
     CDS             2197..2424
                     /locus_tag="L7C88_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HBP9559506.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            2493..2759
                     /locus_tag="L7C88_002729"
     CDS             2493..2759
                     /locus_tag="L7C88_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBP9559507.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            2749..3018
                     /locus_tag="L7C88_002730"
     CDS             2749..3018
                     /locus_tag="L7C88_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBP9559508.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         1101 a          466 c          617 g          944 t
ORIGIN      
        1 tgaaattgct ttcctttaaa atgactcatc gtcattcctc ctgctatctt tttctattat
       61 tctaccttat ctgatagtag atttaaaact ttgcaacaga accagaaaac caaagatcag
      121 cttaacgaat tttttgctaa tgttcttgaa accccttatt ggtatgcaaa aaaaatctta
      181 agccttttat ctgagtgttt agatcaacct gtgtatgaag aggacatttt ctttattacg
      241 ctatattttt atagtttgaa tgtcacgaat gttaaaacag gtattaagag tattgtgcta
      301 gctcatggtt attctacagc tagtagtatg gcgaatgttg ccaaccgtat gctgaataag
      361 aacgtttttc aagcttatga tatgccttta gatattacat tagagaaaat tgaagcaaaa
      421 ttgattcaat tccttggaga ttatcgaaca gattcaggct tgattttatt ggtagatatg
      481 ggttcactaa accaactagg cggtttatta gtgaatcatc taaatggacc actgttaatc
      541 attgatcata tcaatacacc gttattattg gaagtcggcc aacaagtatt aaacaataaa
      601 agtatcaccg aaataggagc agaaattgaa acaagtctta ctttcaaaaa gcagttacta
      661 cttcccaaga aaaagaaaaa gaaagccatc attacttgtt gttatacagg gattggtagt
      721 gcgacccaga ttcaggagat tttaacgaaa tgcttgaaag atgcagttag agaattagta
      781 attattccgt atgattacaa aaagctgtta gaaaacaaga attttgagac tccttttcaa
      841 ttatacgatg tcatcatgat tgtaggtaca gaagatccca aaattaatca gattccatat
      901 attggattag atcgcctgat taatggggga agcattggcg aatttgttca ttacttggaa
      961 aaagagctga ctattgaagt gaacgattta caaaaagaat taattttcaa tttttcaatt
     1021 agtaaaattg tcgaaaattt aaccattttg gatccagata aggtgctatc ttttgtacaa
     1081 aaagcaatta aagaattatc gaagttatta aattttgatt tttctaataa tcagctgttt
     1141 ttgttgtaca ttcactgtag ttgtatgatt gaacgaattg tacgtaaaga aagtgtggat
     1201 gagcaagagg acattgaaga atatatgcaa gcaaatggag aaataatgga taaaattcat
     1261 agcgcttttt ttgagattga aagggaatac acaattgaaa taccagattt agagttgcga
     1321 ttattgagcg atattgttca aggataggag tgaattcgaa tgacaatggg agtaattttt
     1381 gatatggatg gggtactcat agatagcgag acattttatt ttgagagaag aatgaacttc
     1441 tttcaagaac tggagataga tccaggatca aaccagattg atgattatgt ggggaaaaca
     1501 gaagctgcaa tatgggaaac attagttcct gaggacaaat cattaagaga ggaactttat
     1561 ccgaaatatg tagattatcg aaaaacgcat ccaattgatt tcgctaaagc tttacgaaaa
     1621 gaagtgaaac cgttacttga cttcctcaag aagcgggata taccattggc actggcatct
     1681 tcttctccag ctgtcgagat agagagtatg ctcattcaat gtgaacttac tgaatatttt
     1741 tcctttgtta taagtggtga gtcattaaaa caaagcaaac cacatcccga aatatattta
     1801 aaagcgaaac agcaattaga ctgtgacttc tttattgcag tagaggattc aacgattggt
     1861 attaaatcag caaaggcagc aaatatctat acggcggcac taaaacaacc aatgcaaatc
     1921 gatcagagtg aagcagacat acaaattgaa agtctacaag aactggaaca aattgtttta
     1981 gaaaaaggtt agtgaattaa tggaaataag gctatatatc tgtgctagct attttgacta
     2041 accaaaaaaa cttgctataa ttcaggtgta gtaaaaggtg ctggtaacac cttttacgaa
     2101 aatgcttcgg cagtgataat gggattggct ttttaagttt tttattttgt tcgcaatccc
     2161 taaggtcatg tgaatgatcc tagggattgc tagaatattt tgcaacagaa ccaaaatacg
     2221 aatagttatc aagcagccat attgactgcg gtcaatttag gaggggatac tgatactact
     2281 gctgccgtaa ctggtgctct tgcgggtatt ctttacgggg gtgaagtgat ccctgaaaat
     2341 tggagaaaat cgcttcaaaa tgaccagctt cttaaaacga tcagtcagag attttgcgat
     2401 accgtgctat ctcaaagaat ttgaataatg gatatgatgc aaatcttgtt tgtactaacg
     2461 ttgtattgac aaaaaggatt ttatttagta caatgttagt acaaatgatg aacggaggta
     2521 gaatcatgtc tcaatcaacc attacattta ggattcccga cgatgaaaaa gaactggtat
     2581 tagaatatgc aaaagcacac aattcttcat tgaccgaact ttatcgaaat gctgtactgg
     2641 ataaaatcga agatgaaatc gatctacgga ctttacggag tgcaattgaa gtttccaaag
     2701 agaaaaaaga gagtggtatt tctcaagagg aaatggagaa actgctaaat gaattataaa
     2761 gtcatctaca tgccgcaagc ccagaagcaa ttaaaaaaaa tggacagaaa ccaagctaaa
     2821 ataattgtcg cctggatcag aaagaattta gaaaacacga ctgacccgcg tcagcacgga
     2881 aaaggtttga ctggaaataa gagtggggaa tggcgctatc gaattggaaa ctatcgaata
     2941 ttggctaata tttgtgattc tgaaattgaa atccagatat tctcaattgg acatagaagt
     3001 acaatatata aaagataacc gtttttggaa cgaagtagag tttcgaaagt caatgtataa
     3061 tcttttgaat tttgcataat accacaggta gaaactaccc gatactatcg gttggtttct
     3121 gctttttt
//
LOCUS       DAFTHM010000168         3110 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFTHM010000168 DAFTHM010000000
VERSION     DAFTHM010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.171"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(98..1033)
                     /gene="murB"
                     /locus_tag="L7C88_002731"
     CDS             complement(98..1033)
                     /gene="murB"
                     /locus_tag="L7C88_002731"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBP9559509.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1106..2026)
                     /locus_tag="L7C88_002732"
     CDS             complement(1106..2026)
                     /locus_tag="L7C88_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBP9559510.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQEADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2139..2891
                     /gene="xth"
                     /locus_tag="L7C88_002733"
     CDS             2139..2891
                     /gene="xth"
                     /locus_tag="L7C88_002733"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBP9559511.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
BASE COUNT          879 a          632 c          540 g         1059 t
ORIGIN      
        1 aaatgtacaa gatttgcgcc atttgcgtaa acaaccacaa aaaagagcag gacggccacc
       61 gtcctgctct tttacttatt ttaagttcca ttacttatta attggctaaa cttctgcttg
      121 tttctgatat tgcttgtttt tctccaatga tccgcacttc tgtttctaaa gacacatcaa
      181 atttttcttt gattacttct tggatgtgcg caatcaattc aatataatct gtcgctgtcg
      241 catgatcgat attgacgatg aatccagcat gtttttcaga gacttgtgca ccgccccatt
      301 tcaggccttg caatcctgct tgttggatca gctgacctgt atagtgtcct actgggcgct
      361 taaagacact tccgcatgaa gggtattcta atggctgttt tgattgacgc aattcggtca
      421 actcatccat tcttgctttg attgcttcat aatcccctgt ttgcaaactg aatcgagctt
      481 ccaatacgat agcacgtaat tcttggactt tactgtgacg ataagaaaat accatttcgt
      541 cttttgtcaa agttttcaat gttccatctt caagcaaaag atccacttca gcaaaaacat
      601 ctttgatctc tccgccatac gcacctgcat tcatataaac cgctccaccg acacttcccg
      661 ggatgccgca agcaaattca aatccagtca atgattctgc caaagctgca taagtcgtat
      721 caatcagtga ggcacctgct tccgcaatga ccatcgttcc tttgacatga atctgtttca
      781 tttcagtcag catgatgact acaccgcgaa tcccgccatc ttgaacgatc agattgcttg
      841 catttcctaa taccatccaa ggtatatcat ggattcggca ataatcgatg atttgcttta
      901 cttcttcttg ttttttcggg aatgcaagga catcagctgg tccacctgtt ttcgtaaacg
      961 tatagttcat caatggttca tcaaacaata tagtaatcgt ggctaagctt tcaactattt
     1021 cttctttatt cactgaggat tttcctttct tttctcaaac gtcctcatta ttctatcacg
     1081 cttaatacaa tcttgccagt cttgttcaaa gttgatgacg gtagtgatct ttaagcactt
     1141 cctcacataa ttcatgactt cttacaactt ctttttgttt aagcaattct gtttccgatt
     1201 tacctaaacg gatctgagaa aagaaggcct ctaccattgg ctcaaacccg cgtttgacta
     1261 gcgtgtttgt ccagtcgcca aattctttca ctttttttcc atcagcctct tgaatgacaa
     1321 gctgggtcag atcgtttact tcataagtac catttttact tgttacttga tatttttcta
     1381 tattagcgcc acttgctaaa tccatcgtta aaatagccgt ttgattttgt gtttctaatt
     1441 gtaaaatggc atattccaaa aattcctttg tttctcttat ctggtatttt gttctcaaaa
     1501 tgggttcatc taataaatac acagctgtat caataagatg taaaaacaaa tcataaagga
     1561 cgaactctgt cgtttctttt gccgctattc gatttttttg caggtggatc aaccgcttat
     1621 ctgggatacg tttcaattct tctaccatag gagcaaagcg ccggttgaaa ccgatcatca
     1681 aaattatttg gttcttatca gctaattctt gcaattcacg aacttcattt agatggacac
     1741 tcagtggttt gtcaatataa acatggatac cattttctag acattttttg gctaattcat
     1801 aatgtacttt tgttgctgcg tggatcatac atgcttcgat tttttcttct aaaagctcat
     1861 cgatcgtttc atatagatgt tggaacccgt actctttttg aattctttct tttgtttctt
     1921 tatttcttgt tgcaaaataa aaatcaagtg ttccttgttt tttcgcataa gttggtaaat
     1981 atgctttttc tgcgatattc cctacaccga ttacaccaat cttcatctac tttcctcctg
     2041 gatcatttag ttactttcat cttacaccat tttttactaa aatgaggtac aatagtatcg
     2101 caaaggtaag gaaattaatt cgaaggagtg tgcttttatt gaaatttatc tcttggaacg
     2161 taaacgggct tcgtgccatc gtaaataaaa attttttaga agtttttcat gagttagacg
     2221 ccgatttttt ctgtctgcag gaaacgaaac tccaagcagg acaaattgat ttagatcttc
     2281 caggttatta tcaatattgg aattacgcgg aacgaaaagg ctattccggc acagcgattt
     2341 ttgctaaaaa accagcattg aatgccactt acggaatggg tatcgatatc catgatacag
     2401 aaggccgtct gattactttg gaatattccg atttctttct tgtaacctgt tacacgccaa
     2461 attctcaaag cgaattaaaa cgtttagatt accgattaga atgggaagaa gccttttata
     2521 attatttgga aaatctaaaa aaacaaaaac cagtcatcgt gtgtggggat ctaaatgtcg
     2581 ctcatcaaaa gattgatttg aaaaactgga aaacgaatca aaaaaatgct ggattcactc
     2641 cagaagaaag agcggctctt tctcgactgt tggataacgg gtttatcgat acattccgtt
     2701 atttttatcc aacccaggaa ggtgtctact cttggtggaa ctaccgattc aattcaagga
     2761 aaaacaatgc tggttggcgg atcgattact ttttgacgag caaagattta gagccaggac
     2821 tagctgatgc aaagatccat acggacatta tgggcagtga tcattgtcca gtagaattag
     2881 atttgaaata aagaggttgt gaaaaagtcg tttagtttcg agtattaaga aaaattttgt
     2941 gaaaatggct ttccacattt tgcataaatt tggcataata ccgagaaact ggcttttgaa
     3001 cactgtttat cgagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa
     3061 caaaaatagt tcctcatatt tttcgtttgg ttgggcttat taccgcagat
//
LOCUS       DAFTHM010000169         3012 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFTHM010000169 DAFTHM010000000
VERSION     DAFTHM010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.172"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            177..359
                     /locus_tag="L7C88_002734"
     CDS             177..359
                     /locus_tag="L7C88_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBP9559512.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            462..746
                     /locus_tag="L7C88_002735"
     CDS             462..746
                     /locus_tag="L7C88_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559513.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            762..998
                     /locus_tag="L7C88_002736"
     CDS             762..998
                     /locus_tag="L7C88_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559514.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            1020..1274
                     /locus_tag="L7C88_002737"
     CDS             1020..1274
                     /locus_tag="L7C88_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559515.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            1356..1541
                     /locus_tag="L7C88_002738"
     CDS             1356..1541
                     /locus_tag="L7C88_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBP9559516.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            1608..2003
                     /locus_tag="L7C88_002739"
     CDS             1608..2003
                     /locus_tag="L7C88_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBP9559517.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            1993..2370
                     /locus_tag="L7C88_002740"
     CDS             1993..2370
                     /locus_tag="L7C88_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559518.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            2392..2766
                     /locus_tag="L7C88_002741"
     CDS             2392..2766
                     /locus_tag="L7C88_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559519.1"
                     /translation="MKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLWKYKILFL
                     FWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
BASE COUNT         1058 a          507 c          523 g          924 t
ORIGIN      
        1 tttatgttta tgtatatgta tatgaatata aacgtattag gtacgaacac ttttaaattc
       61 ttttctgggc tttgttttta gggtagggct aaaaaaaaca tcaccatctg atccaaaaca
      121 gctcagaaac gcattttaac gtatctgata ccaatattac agaaggagtg tatcgtatga
      181 ttaacctatt tcttttagtg acagctagta cattattctt tactggaata tcactgataa
      241 tttcctattt gatctataag aaagccgaaa atcacacaag caaagcaatc ggactagccg
      301 tttcatcctt tttaactttg ctgactttat ttgttacttt atcgttttct tttgtttaga
      361 acagctgatc cattagcacc tttttctctt tacattatac acactgttgt gtataatgta
      421 tttgtaaaca agctaattaa cttttaggaa ggagtgacaa gatgctaaca gctactttac
      481 agcaacctac tcacgttgct attgcagaaa gttatacaat taatgcaggg atcgttaaac
      541 agctgatcaa ggatcgagaa ttcaaaaagt ttaacagtcg gcaagcgtat aacagacagc
      601 taaagaaagc tattctaaag cacaaagatt ccttcatcgg gaacttggaa agtgtagatg
      661 ttaaaactgt ttcaacggca ttttcagttg ttgaagtgac tattgacggt cgcttgattt
      721 ctctatttgc ttttggaatt aattgatagg gagtgtgaac tttggaaggt aagacttttg
      781 cagaaatttg gactgaattt attgaggtac caactcgcat tgatccgata acttctgaaa
      841 aggtattgga tgcagacttc tacaatctca aagcaggtac tagccttgaa tgcgtttgga
      901 tgtatttaga agagcatttc aaaggcgtaa cgctcggtca cgtcttatac cacaatggtg
      961 ccgagtggga tgcaattgga aatatccatt tttcttaata taagaaagga gaacacaata
     1021 tgaattatac cgatgaagaa caaatcgctt tggaatacgt tttcacaaat gaagaagggg
     1081 aggaaattga aaaagtcttg atcatttcat caaaagactt ggagaaggct ttggcttatg
     1141 aaccatacga atcaaccgta actgtcattg aattcttaga tacctatact tctaatgata
     1201 cttgggaaat tatgaatatt tgcaacgcta ataacattca atttgctgaa aaaaccaata
     1261 aatcatttta ttagttttgc aataaaacat cctctttttc tattgattcc atacacaaca
     1321 atgtgtataa tagattttgt aaagggaggg tagctatgcc taagacagca agagaaattg
     1381 taaaaattct caaatctaac ggcttcaaaa agactggaca aactggcagt catgcaaaat
     1441 tttataattc caagactaaa agaacggtcg ttgttccgat ccacaatggt gatgtaccac
     1501 taggaacaga agctaatatc tggaagcaag cagggcttta acagccttgc cttcctattt
     1561 ggtattaggc atactatcct ctcttacact agaaaaggag cgaggaaatg aagacaaaaa
     1621 atatttttta tccggcaatc ttcgagaaag aaggagaagc ttataacatc gttttccctg
     1681 acttaccgga aatatctacc tttggaaata gtcttgaaga agcatattta aacgctaagg
     1741 atgctttagg attagcgcta tatagtgtac cagatgcaga atttcctaaa ccatcagcag
     1801 tggaagaatt aactttgaaa gccaaccaag tggtagtaat catccaacta aacattaaac
     1861 ttttccgaag aagcttaaat acaaaaacaa ttagaaaaaa tgttagtgtt ccggaatggt
     1921 tagttctttt agggaaggag aaaaacataa acttctctca actacttcaa aaagcactag
     1981 aagaagagtt gcttgaaaag taaaaaggag accgaaccta tgaaagctac acacttaaac
     2041 tatttctctc gaacgttaat caataatcta ttaaaagata caactggcat tagcgttagt
     2101 accaaacact ttgccaatga tctaattatt tttgaggata ataacttgcg aattgagatg
     2161 tttattgaac aggcaacccc taactcaata cctgaattct gctatacgca cactgaaaaa
     2221 atgaaacatg caaaatcagt taaagatgtt gaagcattaa gtgaatcact aacgaacgct
     2281 ttaaacctcg ttaagaaggc aaaattgtta tttgaatttc aaaccgacta ccacaatgag
     2341 ttgcttgctc aatctgaaat tttagattaa ttgaaacagg agaagagaaa gatgaaacaa
     2401 acacaaacag aaaccgttaa cgatacgctt gctgatcaat tagcaggtta ttataaatta
     2461 tttgagatgg gtaaagcaca gcgcttgatc cactatcttt ggaaatacaa aattttgttt
     2521 cttttttggg aatcaacact aacattctca gttctttttt ataagtcaga tttttataat
     2581 caacacttag ttttagggag ttttttgctt atctacacca ttttgatgct taatttatat
     2641 acctacatca cacttgaaga acacttagta attagcgatg cagggatcga gagaaacatc
     2701 aaaagggtat ccttcaagat cacgttaaac aagcctaccg ataaaaagct ctcagaagcg
     2761 ttctgagagc ttttgacatt ttcttgtata attttatcct aacacattac aaagcaccta
     2821 attcgagctt atatcaagca aatttgctat ttattactca atacatatct aaaaattact
     2881 tgatggaaaa ttagatacat ggtaagcatg aaaagaaaat caatttgagc agatgcagta
     2941 caatacatag caatttaaaa gctctcagaa ggcttctgag agcttttaat atattctttg
     3001 ataatttgtc tt
//
LOCUS       DAFTHM010000170         3002 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFTHM010000170 DAFTHM010000000
VERSION     DAFTHM010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.173"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            974..1228
                     /locus_tag="L7C88_002742"
                     /pseudo
     CDS             974..1228
                     /locus_tag="L7C88_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1298..1810
                     /locus_tag="L7C88_002743"
     CDS             1298..1810
                     /locus_tag="L7C88_002743"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559520.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLY
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            1807..2844
                     /locus_tag="L7C88_002744"
     CDS             1807..2844
                     /locus_tag="L7C88_002744"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBP9559521.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1081 a          516 c          596 g          809 t
ORIGIN      
        1 aataaaagac cataacaaag tggttgataa atcgaataca gcgctaaaag tgatgacaaa
       61 aggcgttaca aatatatttt ttgtgctaat tatttttgta cttgtaatgc ttgtgacagg
      121 tccgataggt catttctttg gtattgaaca tttatatagc tttattaatg gttttattga
      181 tgaccacgaa agtgcatggc gatatttgat gttgatactt tatgcagtac cctatgtatt
      241 cttcgctatc attctgtggc tcatagcatt gttttttaga gtatttaatg acctttaggt
      301 agatttatat ataaaaaggg ctaaatacgc aaaatacccc cttaaaatgc aaaataaatg
      361 caaataaggg ggtaactcct tatgaaaaaa caactaatag tattataaca cgtttttatg
      421 ccgagaaaac ttattggttg gaatgggcta tgtgttagct aacttgttag cgagttggtt
      481 ggacttgaat tgggattaat cccaagaaag taccaactca acaacacata aagccctgta
      541 ggttccgacc aataaggaaa ttggaataaa gcaacgaaag gagttgagta aaatgagtga
      601 gaaaacgaag aaaatcattc gagtatcatt agctttttca caagtagtag tgcaatcatt
      661 gatagtttat tatacttacc agcaatataa attatctaaa gagaattaag ttttgattat
      721 gtaataagtt ttggtactaa aaaagacttg atctaattag accaagtctt ttgttagtgt
      781 tatattaata acaaaataaa aataagaagt cgctcactcc ccgaccaaag tttgtgagca
      841 aaataaacag tcgatgtttg tttcttaatt gtatatcttg atattaaacg atttaagatt
      901 attcttcaag atatatattc gcaaatgtaa ttggaaaagc gacttcttaa acaaaattaa
      961 ggagtcgctt tttatggcaa aaataacgaa aaatgagcaa gaaaatttgg tggaaaatta
     1021 cacaaaaaaa ccggcgtact ctaatagccg gttagacgca catttcgtgt gcacttctaa
     1081 tccgaaattg agctttgacg ctatgacgat agtcggaaac cttaataaaa acagcgctaa
     1141 aaagctatcc gattttatga gtttagatcc acaaattaga ctttgggata tacttcaaac
     1201 aaaatttaaa gctaaagcac tacaagaccc cctatgttag gctagttgtc gtataggata
     1261 ataagttata ataaagacta tacggaggat gattaccatg acaaataaaa acaatgaacg
     1321 ttactctacc gaactgaaag cgacagccat caagaaaatg atgccacccg aaaatagggg
     1381 gattcgccaa ttaagtcaaa ctttgggcat tccagaagcg actctttatt cttggcgtaa
     1441 aaaagctaga attcaaggga atactacacc cggaacgaaa aaaaatgtcg aaaaatggtc
     1501 aagtgaagat aaatttttaa ttgtgatgga atcattctca atgaaccaag tagaacttgc
     1561 ggaatattgc cgaaagaagg gcttatttaa agaacaaatt gaggcttgga agaaaacgtg
     1621 cttatctgcg aatgaacagg aagaaaatcg aacgagagaa cttgcaactg aactaaaaga
     1681 agagaaaaaa caagcgcgtc aattagagaa agaattacgt cataaggaaa aagcattagc
     1741 ggaagccgct gctctcttat tactaagaaa aaaagcacac gcgatttggg gggaccaaga
     1801 ggaagaatga tttcatcttc agatcgcaaa caagctgttg aacttattca agaagccaat
     1861 cgcaatgggg cccgtctcac ctatgcctgt aatgagctga atattagcgt tcgaacctac
     1921 gaacgatgga cgcgtgaagg tacgatagcg catgatcaac gccctttggc gaaacgtcct
     1981 gtacccaaaa ataaactgac ggatcaagaa cgcgaaaaaa taatagaaac cgtttcaaaa
     2041 aaagaattta tgaatttgcc acctagccaa attgtaccaa aacttgcgga ttgctcgatt
     2101 tatattgcat cagagtctag cttctatcgt gtattgcgag aaaaaaatat gcaacatcac
     2161 cgtggccgaa gtcaagtttc acaaaaacgc ataccgccaa gtcaccttgc gacgaagcca
     2221 aatgaagttt ggacttggga tattacttgg ctaaaaggtc caataaaagg actcttttac
     2281 cggttatatc tcatcattga tttatttagc cgtaaaatgg taggctggga gatttgggaa
     2341 tcagaagaag ctcgtcatgc cgaaaaactt attaaacaga cggtgcttaa ggaacgtatc
     2401 caaggacagc cgttggtttt acactccgat aatggcagcc ctatgaaagc cgcgactttt
     2461 caagtcttac tcgaaaaatt aggaattcaa agttcttatt caagaccacg agtgagtaat
     2521 gacaatcctt attcggaagc ggctttccga acgttaaaat atcgaccaga atatcccaat
     2581 aacggcttta aaacaataga tgatgctcga aaatggacga aagagtttgt cgattggtat
     2641 aacgattctc atttgcatag tgggattcaa tttgtgtctc ctgcagcgtg tcatgaagga
     2701 cgacatctcg ctattttaga gaaacgaaag caggtttacg aggacgctaa aaagcgccat
     2761 cctgaacgct ggtcaaaagg tgttcgaaat tggactccac atcaatcggt ggcgttgaat
     2821 cctttaaaag aaacagaaag ttaacaggag cataatcttt caagattatc aaataaccct
     2881 cgtcacccaa taggggaaaa agttattctt cccctattgg ataacgaggc caaccgacca
     2941 tagggaggtt ctgctttttg ataggtggaa aataaaaata cgacaactat attgacaaac
     3001 ac
//
LOCUS       DAFTHM010000171         2975 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFTHM010000171 DAFTHM010000000
VERSION     DAFTHM010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.174"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..322
                     /locus_tag="L7C88_002745"
     CDS             <1..322
                     /locus_tag="L7C88_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559522.1"
                     /translation="IINREKVSELPLAEFLESEYETLGVKYSQTIKKALNLYRRVKNN
                     EVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQAHPSTVTSDHSAKKEKPMLKGFNAPSN
                     KDLL"
     gene            complement(504..800)
                     /locus_tag="L7C88_002746"
     CDS             complement(504..800)
                     /locus_tag="L7C88_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559523.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(804..1622)
                     /locus_tag="L7C88_002747"
     CDS             complement(804..1622)
                     /locus_tag="L7C88_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9559524.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            1848..2069
                     /locus_tag="L7C88_002748"
     CDS             1848..2069
                     /locus_tag="L7C88_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HBP9559525.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            2071..2337
                     /locus_tag="L7C88_002749"
     CDS             2071..2337
                     /locus_tag="L7C88_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBP9559526.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            2450..>2975
                     /locus_tag="L7C88_002750"
     CDS             2450..>2975
                     /locus_tag="L7C88_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559527.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVGTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKLQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDV"
BASE COUNT         1020 a          526 c          473 g          956 t
ORIGIN      
        1 tataatcaat agagaaaagg ttagcgagtt acctttagca gagtttcttg aatctgaata
       61 tgaaacacta ggcgttaaat actctcagac gatcaaaaaa gctttgaatc tatatcggcg
      121 tgtaaagaac aatgaagtta caattattga agcaggcaac gatagaaacg atagcaaagt
      181 agctgaagta aagaataaac caactgatca taaccctatt caacaagcgc atccttcaac
      241 ggttacatcc gatcattcag caaagaaaga aaagccaatg ctaaaagggt tcaatgcacc
      301 aagtaacaaa gacttacttt aaaaataaaa aggcgaggtt acaataccta gcctttttat
      361 tatgtacaaa tacaaacata aacatatacg tatacatgta tataaacatg tatacgtata
      421 tatccataaa cacgtatacg aaatttagtt aagctatacc taaccgctta ttccaataaa
      481 aaaagtgatc agctttaaac tgatcactca ccaaaaactt catcatacaa gttatctatc
      541 atttcaccaa gtaaagctga atctgatcga attcctaact tttcgctgat tttagatagt
      601 ttctttcttt gtgatggttg aagcgtgaat tgataatttt tcttcttttc agaactatca
      661 ctttttagtt tagctaccaa agaacttgtt gtttctttag gtgtttgttt aggttcttca
      721 actgcttcaa ccacttcagg aacttcttct acttcagctt cagcgaattt tttaaatcta
      781 ttttctttca cttcaatcac tccttattct tgtgccgtat caattatttt gttgtatagc
      841 gtaaacgtgc tttcaaagaa atccttattc ttacgataga tattcttatc cttagcgaac
      901 tcagcaatat tcttaccttc taagctagtt gcattaagca attccttctc ttgtacatat
      961 ccaagataat tagataacgt tggtaccaat tctaggaact cacgacttga attagtatta
     1021 tgtttgatcc tgctaccgat cgtagcgtat ttagtttcca tcagtgtttc accagtctta
     1081 atatcaatca actgttttgc tagtgcatca atatctttac caagcttaag caaagcttca
     1141 aaaccatctt tagatggatc agaaatgcct acgacaagat cagatacagc ccaagcattt
     1201 tgagctagta gacctgcatc attatgagta tcaatcagaa ttagatcata cttctcttta
     1261 agctgttcat agttaacaac gatccatcta aacagtaggg ttctgttgtt aggcatatca
     1321 cgcatttgca tctcaacttg ttttaaatct tcacctgcta ctaaaatatc catgttctca
     1381 tttatagcta aaggttcagc tgatccatga agatataaat gattgattgt attctctctt
     1441 ttcgctttac tgaaagcatc aggaaatcgt tttgataggt tttgcgactt atcttcatca
     1501 atatacagca ccttcatacc taaattttcg acagcatatc cacctagatt gtagattgtt
     1561 gttgttttac ctgttccacc tttttcaatg tttccagtaa tgattgacaa cttcttttcc
     1621 atgattaaac ctcccttatt aatcttttgt aactccatta tacactataa acacgtttat
     1681 gtatatattt atatacataa acgtgtttat atttatattt gcttttatat tctacaacat
     1741 aaacatatat atgtatatgt ttatgtttat gtatatattc aaatatataa ctattgcatt
     1801 tgtcatacaa tcgtagtaca atgtaattga aaaggagttg ataaactatg ccagtaataa
     1861 gtattcgtgt atctaaagaa gaaaaagatt ttcttgaaaa agttgctgaa ttcaacggag
     1921 ataacatttc tgaatttatg cgtagtaatt ccctgcaaac agcagaaacg ttagtagact
     1981 ttgccaccta caagcaacta atgaaagagc atgaggaaaa cgatcaaagt atttcccacg
     2041 aagatatgct aaaagagtta ggcttataag atgacttacc aagtaagata tgaacgtgaa
     2101 gctcaaaaag cgctaaaaaa aatggataag tttcaggcaa aggttatcct aaactggatc
     2161 gagaaaaatc ttgtaggcac tgatgatcca agaaagcatg gtaaaggtct aacagctaat
     2221 aaatcaggct actggcgata tagggtaggt gcataccgta taatagctga tattagcgag
     2281 catgaagtga caattcttat attgtctatt ggtcacagaa gtgaagttta taagtaacag
     2341 acaagctgat aaggcttgtc tgtttttttg ttaacccaac aaaatcactg tttacgatcc
     2401 cactttacct aaaaaagaac aatatcctct tgatattata cacaccagtg tgtataatat
     2461 aagtgtaaac aagctaatta actttcaaaa ggagcgattt tttatgggat ggtatggtga
     2521 ttattcatca gcaaatgaag tgatcgaaga aaagaaaggg tacgccaaaa atggtttgga
     2581 aatcgtaggt accaaagtaa cgaagaccta tggaattatc cttttcaaag atgcagaagg
     2641 aacctacgat attgacagct tcatctttcg agatgaaatg tacaaaccaa tctacttctt
     2701 aaatgacagt cctgcttact ttaagaaaat tccgaaaaaa tggttgaaat tctttgtcgg
     2761 tgatcaagaa aaaatggtta agctacaact agatagaatt aaagaagaaa gcaataaacc
     2821 aaaacttgat gacttattag ttgcaggtaa aacttactca atctgggatg gatcgtatgt
     2881 cgctgtctat cagtataaac tcaaacgtag ctttattttt cgactacaag atggatcact
     2941 cactcggttc actcgactat cagcaggaga tgtta
//
LOCUS       DAFTHM010000172         2949 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFTHM010000172 DAFTHM010000000
VERSION     DAFTHM010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.175"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..386
                     /locus_tag="L7C88_002751"
     CDS             <1..386
                     /locus_tag="L7C88_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HBP9559528.1"
                     /translation="KYLKTDIIYITNLEPEEYLTILKECKFMIGNSSSGIIEAASFKI
                     PVINLGTRQNGREQSKNIINANLNENEIETALNKIQDPQFIKSLKNVKNIYGDGNSSR
                     RITKTLNQILNDGEDIKWIQKQIAY"
     gene            359..1036
                     /locus_tag="L7C88_002752"
     CDS             359..1036
                     /locus_tag="L7C88_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBP9559529.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            1026..2168
                     /locus_tag="L7C88_002753"
     CDS             1026..2168
                     /locus_tag="L7C88_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBP9559530.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            2181..>2949
                     /locus_tag="L7C88_002754"
     CDS             2181..>2949
                     /locus_tag="L7C88_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBP9559531.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFS"
BASE COUNT         1093 a          376 c          571 g          909 t
ORIGIN      
        1 agaaatattt aaaaacggat attatttata ttacgaattt agagccggag gaatacctga
       61 ctatattaaa agagtgcaaa tttatgatcg gaaattcttc ttctgggata attgaagctg
      121 catcattcaa aataccagta ataaatttag gaaccagaca aaatggacga gaacaatcta
      181 aaaatattat aaatgcaaat ctaaatgaaa atgaaattga aactgctttg aataaaatac
      241 aagatcctca gtttataaaa agcttgaaaa atgttaagaa catctacggt gacggcaaca
      301 gttctagaag aataacaaaa acattgaatc aaatattgaa tgatggggaa gatattaagt
      361 ggattcaaaa acaaatagct tattaaaata tactagtgat ccatacatta ttattggggc
      421 tggcggacac gcaaaagtca ttattgaaac cttaagatta gaaaataagt taatatatgg
      481 attttttgat gataagcaaa ataaaatgca agatctgaaa tatcttggga aaataaacga
      541 attgaatagc tgggcggata gcaaaaaaaa aatctataaa tttattgtag ctattggtga
      601 ctgtgtagta agaaaaaaga ttataaaaaa attgaatatg ccaagtgagc aatatggaat
      661 agctgttcat ccaagtgcta tagtggcaaa agaaatttca attggttatg gaactgttat
      721 ttttgcgaat gctgtaatta acccagatgc tgtaattgga gagcatgcta taataaacac
      781 aggtagcatt gttgagcatg attgtagaat taataactat gttcatttat ctccaggtgt
      841 atgcttagcg ggtggagtac atgtaggtgt aggaactcaa ataggaattg gttctcaatg
      901 tatccagatg aagaaaattg gatcttggtg tatgataggc gcagggagca ctattgttaa
      961 ggatattccc tcacattcct tagcttatgg caatccagct aaaattaaga aagaaggaat
     1021 taattttgaa ttctagaatt ttattatcaa gtcctcatat gggaggaaca gaagaaaaat
     1081 atgttgctaa ggcttttaaa gataattgga tagcgccatt aggtgaaaat gtggataaat
     1141 ttgaagaaag tattacaaaa tatactggtt ctaagggcgg agcttctgcg ttaagttcag
     1201 gtacagctgc catacatctt gccttaagac tgcttaatgt tggaaaaaac gatattgtct
     1261 ttgctccttc atttactttt atagctacag taaatcctat tttatatcaa ggggctgtac
     1321 cagtgttcat tgactcagaa cctaatacat ggaatatgag ccctgttgca ctagagagcg
     1381 cattagaaga agctgaaaga aacaaccaat tacctaaggc aatcatcgta gtgaatttat
     1441 atggtcaaat ggctgattat gaacgaattt tagctattgc aaaccaattt aatgttccag
     1501 tgatagaaga tgcagcggaa tcgttaggtt ctacttataa gggaatttcg tcaggcttat
     1561 ttgggacaat tgggatctat tcatttaacg gtaataagat catcacaacc tcaggtggag
     1621 gagctctagt gtctagtgat aaaaaatatg ttgagcattc aagattttta gcaacacaag
     1681 caagagatca agcaccgtat tatcaacata gcgaaatagg ttataattac cgtctaagca
     1741 atatttctgc cggtatcgga cgtggacaaa tggaagtatt gaatgataga gtagctaaac
     1801 gaagagaaat tttcaatcga tataaggaag ctttttctgg aattgataga attgaaatga
     1861 tgccagaagt ggatggcatg gtgccaaatc gttggttgtc tactttaacg atcaatgatt
     1921 ataattctat tgatcaagta gttaacgtaa taaataaact aaatgaaaaa aacattgaaa
     1981 caagagcttt gtggaaacca ctacatttgc aaccagtatt tcaaggggta aaaatgtatt
     2041 accatgataa taatcttagt gtgtcagaaa agttatttaa tagcggctta tgcttacctt
     2101 ctggaagtaa tatgacagat agtgaacaag aatttgttat tgatgagttt aaaaaaatat
     2161 tcaagtaggt gtgatatttt atgaacatag gaattattgg tttaggttcc atggggaaaa
     2221 gaagacttag actcattcaa gaacacttta atgatatttt actatgtggt gttgatacta
     2281 atgaggcgag acgaaaggaa gttgaaaagg aatttggaat accaacttat aatagtctaa
     2341 cagaggcaaa aaatttgttt gaaataaatt cagtttttgt ttgtacatcc cctataaccc
     2401 atgaatttat tataaaagag gctttaaatt tagattgtaa tatctttacg gaaatcaatt
     2461 tattaaatga atattatgat gaaataatcg aagtagctaa aaagaaagat agattacttt
     2521 atctatcttc tacatttttg aagagaaaag aaattcaata tattaagtct aaagtgacgc
     2581 ataataaaaa aatttcttat caataccatg taggacagta tttacccgac tggcatcctt
     2641 gggaagatta tcgcaatttt tttgtttcaa acaaaaaaac taatgggtgt agagaaatat
     2701 tcgctattga attaccttgg attatagata catttgggaa agttaaatcg tttactgtaa
     2761 tgacccagaa attatccaat cttgatattg attattcgga cagtttcact cttattattg
     2821 agcatgaaac tggtatagtt ggaactttaa gtgtagatgt tgtttcaaga gtagctaaaa
     2881 gaaatttaac tataattggt gaaaagattt taatagaatg ggaaggtaac ccggattctc
     2941 tattttcat
//
LOCUS       DAFTHM010000173         2948 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFTHM010000173 DAFTHM010000000
VERSION     DAFTHM010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.176"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..1350
                     /locus_tag="L7C88_002755"
     CDS             <1..1350
                     /locus_tag="L7C88_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBP9559532.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="L7C88_002756"
     CDS             1484..2827
                     /locus_tag="L7C88_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBP9559533.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
BASE COUNT         1171 a          398 c          561 g          818 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaat
//
LOCUS       DAFTHM010000174         2741 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFTHM010000174 DAFTHM010000000
VERSION     DAFTHM010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.177"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(75..1169)
                     /locus_tag="L7C88_002757"
     CDS             complement(75..1169)
                     /locus_tag="L7C88_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBP9559534.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            1358..2119
                     /locus_tag="L7C88_002758"
     CDS             1358..2119
                     /locus_tag="L7C88_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBP9559535.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(2234..2674)
                     /gene="fabZ"
                     /locus_tag="L7C88_002759"
     CDS             complement(2234..2674)
                     /gene="fabZ"
                     /locus_tag="L7C88_002759"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBP9559536.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
BASE COUNT          867 a          549 c          465 g          860 t
ORIGIN      
        1 ctataaaaaa acaaaataaa aaagcagaaa taactggcta tttctagcgg attatttctg
       61 caataactaa ttatctattt tttattttca attaatttaa agcttgacca tggtttcaaa
      121 aagtcaagga ggaataattc gtcatcggag attcttccta caacattgac acgtccgtcg
      181 tttttcatat ccttcaaggc gatttgtgtt tctcctttgt attgaccgta cccttcattg
      241 tcaatcagta catccccatg atgcatatct cgcgtattat gaggcgggaa atctttatct
      301 ttgtagtata cacgagtcat cgttgaacga aggatatatt ctgagcgatc ccctcgataa
      361 ctatgaaggt tatcaaacaa gcagattcgt tcgttttctg taataccttc ttccgtatct
      421 actttcaatg ttggataatc cgcgttaaat gcttctgcca tttctttcaa ttcttcttca
      481 cttgcgtacg catttccaat agaaatatca tcaatcaatc ctgtaaggat taaatgcttc
      541 acttgtgtcg caatttcaag atctcggtgg tcttccagcg tgcacaagcc atcttgcgta
      601 ggccaagggc caaactcagc agattgcgaa ttgacgaatg ccatcgtatt caaattatat
      661 tttctgaatt tttctgaaca aaaaacaaag tgttcgtatc ctaaaccaga gtatcgatga
      721 ggataaaaat tatgagaacc taataaatta tccgtgtttg gcgaataact catgatgttg
      781 tcaacgtaat tcgtgcccga actcatattg atctcgattt tgataccaaa aggattgcgc
      841 gtcatttttg cttcttctgc tcctgtgaat ccgatatcta agcggacccc gtaggcaccc
      901 atcttatgga aaaaagataa gtcatcgtaa gaaatctcca actgttcaaa taacgctgga
      961 ttgatatcaa ccattacttc catgcctagg ctattcgcgt aatcaactac ttctttaaat
     1021 tctgaaagaa ctttttcttt atcatcattg atctgcagca aactggtaaa aacccgttta
     1081 tacccatact tatgagctaa atccaagtac gctttgtcct tttcaaatgt tgaccgttct
     1141 ggataaatcg agattcctaa ttttcccata ttaccatttc ctcctgcatc ttttcgtttt
     1201 tgtatccact tacattatag caaacacaaa gtaaatggtc tacacctttt ctttttcttt
     1261 taaaataaat gataaattcc aataatttaa gtaggtattt tccctctatt ttgttatcat
     1321 taaagataac aaaatagtaa attggaaagg aacagttatg aagaaaaata aagttatttt
     1381 aagtattagt ttagcagcag cattgctgtt tgctgctggt tgttctgcaa acaacacgac
     1441 ttcttctagt tcgtctacag aaagttcaaa aagtacatct actgcggaaa gcacgactgc
     1501 cagtagcgtc gatttgaacg cattggaatt accacaattg acgaaagatg tcgccgaaaa
     1561 tgaagatctg gtcgaaatgg tgacgaataa aggcacaatc aaaatcaaat tatttcccga
     1621 acacgcacca aaagcggttg aaaactttat gacacatgca aaagacggtt actacaacgg
     1681 actgactttc catcgcgtca tcaaagattt catgatccaa ggtggcgatc ctaaaggcga
     1741 tggcactgga ggggaaagca tttggggaga aggatttgaa acagagatca acaaccacct
     1801 ttataatata agaggtgcgt tatctatggc tcgctcacaa gatcctaaca gtaacggcag
     1861 ccagttcttt atcgttcaaa atacagatga tatgcatgat ggtcttttaa aagacgacta
     1921 tcctcaagca atcatcgacg cttataaaaa cggcggttat ccttcactag atggccatta
     1981 tactgtcttc ggccaagtga ttgaaggaat ggatgtcgtg gatgctattg caaatatcga
     2041 aacagatagt tcagacaaac caaaagaaga agtaaaaatc gataaaatca atatactgca
     2101 agaagcaaaa caaaaataaa aaaataacgt ctgaatcctg catagatgac aacgtatgct
     2161 aggattcagg cgtcttcttt ttacataaaa agcaagtaag cttccttttg ttttgctata
     2221 tcaggtttta tagtcaagca ttttggttga cgatgaacgt gaactcgcac tcacagactt
     2281 ttttatcatc tacatatgct gcagataacg ctgtaccgac tgatcccttc attttggtga
     2341 tttcaaaatg acatttcagc acatctcctg gaacaacttt ttgacggaat ttggccttat
     2401 tgatcccacc gatataagct ctttttccta gaaactcttc tgattttagg ataagtatcg
     2461 aacctgcttg tgccagtgtt tctagaatca acgcacccgg catcactgga ttgtcaggaa
     2521 agtgaccttg gaaaaaatct tcattgattg ttacattttt tgtcgcaacg atcttttttc
     2581 ctggttctaa agtatctaca taatcaatat aacaaatagg ataacgatta ggaatcaatt
     2641 ccattacttc agtagcagat aatacgtaag acataattaa actccttctt tcaggcaatt
     2701 gccattttca ttactttgac tatcaaagta tcatattcct a
//
LOCUS       DAFTHM010000175         2739 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFTHM010000175 DAFTHM010000000
VERSION     DAFTHM010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.178"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="L7C88_002760"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="L7C88_002760"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBP9559537.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1072 a          425 c          558 g          684 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatcag gaacttacct atccatata
//
LOCUS       DAFTHM010000176         2724 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFTHM010000176 DAFTHM010000000
VERSION     DAFTHM010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2724
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.179"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(88..1035)
                     /locus_tag="L7C88_002761"
     CDS             complement(88..1035)
                     /locus_tag="L7C88_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBP9559538.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
     gene            complement(1040..1792)
                     /locus_tag="L7C88_002762"
     CDS             complement(1040..1792)
                     /locus_tag="L7C88_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBP9559539.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            complement(1793..2701)
                     /locus_tag="L7C88_002763"
     CDS             complement(1793..2701)
                     /locus_tag="L7C88_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HBP9559540.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
BASE COUNT          888 a          516 c          340 g          980 t
ORIGIN      
        1 ttctatccca gatttgattt tacaaaactc atcagtcctt attgacaaag agcctgaatt
       61 taccctctaa tcttatctta gtatgtttta attgatttca gttttcaaat aattagtcat
      121 tccacttaaa ataccatatt tcggttgata gccaattgac tggatcttag taatatctgc
      181 tagagagtca tggatatcac ccgaacgctc ttctttgtat tcaagtgtca attctacacc
      241 gagaatttca ttgattgcat gaatcaattc caaaagtgtg gttgctttac ccgttccaac
      301 attgaattgt ttccccagtg cagcttcctc attcgcaact aaaagtaatg cttggattac
      361 atcatctata taaacaaagt ctctagactg gcttccatca ccaaataatg taaatgaagt
      421 tgcttctcct acgatttgtt tcttatagcg atctacgaga atagaaatca caccactgta
      481 tggagaattc ggattttgat ttggaccata gacattgaaa aaacgaactg cgctaccggg
      541 tacatcatat aaatgacaat aatctagcac atattgttct gcagcgaatt tatcaaccgc
      601 ataaggcgtc aatgggcgaa tcacggactc ttcttttttt ggtaaagtcg gttcatcccc
      661 ataaacagcc gctgaagaac taaacacgat ccgttttaaa tcaggttgat acttgcggat
      721 caattctaaa atcattaata cactttcaaa attcacacga tgtgtttcta ctggtcgggc
      781 aactgaatct gccacactag caactgctgc taaatgaaag atataatcaa atttattagc
      841 tttcatgatc tcttccatca aggatttctc agcgacatct ccctcaataa aagtgatatt
      901 tttcgtcata tcaagatttt ctacttttcc cattgataag tcatcgacga cgattaccac
      961 atgttcttct cctaaatgat tggctaaggt agaaccaatg aagccagccc caccggtgat
     1021 aagataacag ctcatccttt tacctccgat ataaataatt atagatatct tgaagctccg
     1081 aagaatcttc taaaaattta ggaaacaaaa attctaacca tttaaaatct tcttcactat
     1141 caatatctaa aattagataa tctctcattt ttattatccc acattgccca tcaaaaatat
     1201 aattactttt ttttagaaat tcaggtttaa aagaatacat tgaggcattc atttcaaaaa
     1261 cttcaggtgt ctgttgccta gatgtgtatc ttgatttatt aactatagta acttcatttt
     1321 caattctttt taccatatta aaatagggat tacgtcttgc agaaacaact gaaaagtaga
     1381 cgtctttatc taaatttttt agatgttcat ctattaattc ttcaagatta gaaacttcac
     1441 gtaaaggtga agtcaaatct aaatctataa ttaaatcaaa tatattatct tctctttcta
     1501 gttgtaagaa tgaatcacgt atcacttcaa ttttccctac agtatctgta gctaattcag
     1561 gtttacgttc tacaattttc acagacggat ttaacttagt cgtcaattct actaactcat
     1621 tactgtccgt attcaaacaa gtcgtgcaat tatgttcagg atgtttttgt tgatagatat
     1681 ctatcattgc taaagcgaaa tggactaggg gctttcctgc caaatatttc aaatttttat
     1741 ttttaaaccc cttagaccca gctctaccac aaatagtaaa taaaatttcc atttatttct
     1801 cctcagctat tttcaatact tcgtttgcat gatataaatc attccagttt tctttgcctg
     1861 ttactacgtt ttcaaagaaa tatttcaact ccttctcata catatcatta gcagattcag
     1921 gcatttcttt aacaatgttt tcttcaaaac ttattttatt atttaataag tcaacattga
     1981 tacattcatc taaagtaaac aattgaaatt ttcttgtagg aactcttcca aaataatcta
     2041 aatgaatttc tataatttta tcatcgtatc tcaatatata tgttgctaaa tcattactgt
     2101 taatttcaag attcgaatat ttaccaaact gtttttttac tgatttaggg aaaccaaata
     2161 ggtttataat ataatccaat tcatgtatac agtctaattc tactcctccc cccatagatt
     2221 taaaggcaga ataattattt ctataatcag taccttttct ccaatcagga agataagtag
     2281 aacaaatagc tcttacagaa tatacttttt tactttgaat actattacga acaacttcca
     2341 tgatattttt atacctcagt ggagcagcaa cataaatatt tttgtaatca taattatatt
     2401 gagtaagatc aatactctca gaaaaagcag gtttttctaa aaatatgtaa tcaacttttt
     2461 caacaattac atttagtgtt tccagatgct taaaagtcgg atttgtaata aaagctatat
     2521 cataatgtgt atccaaatcg tctctatttt gaatatacgt tatttcttca aactcttttt
     2581 ttccactgct actataagct gttatatcaa aattaataga attctttttt ccatagctta
     2641 ttagattttt tagatgtctc tttccaattg accctaaccc aaaaaaaatt actttcatca
     2701 ttaatttacc tcaatgtcgt taat
//
LOCUS       DAFTHM010000177         2446 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFTHM010000177 DAFTHM010000000
VERSION     DAFTHM010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.182"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            157..549
                     /locus_tag="L7C88_002764"
     CDS             157..549
                     /locus_tag="L7C88_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559541.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
     gene            complement(722..904)
                     /locus_tag="L7C88_002765"
                     /pseudo
     CDS             complement(722..904)
                     /locus_tag="L7C88_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            891..1088
                     /locus_tag="L7C88_002766"
     CDS             891..1088
                     /locus_tag="L7C88_002766"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559542.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(1131..1706)
                     /locus_tag="L7C88_002767"
     CDS             complement(1131..1706)
                     /locus_tag="L7C88_002767"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBP9559543.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(1861..2387)
                     /locus_tag="L7C88_002768"
                     /pseudo
     CDS             complement(1861..2387)
                     /locus_tag="L7C88_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          777 a          419 c          381 g          869 t
ORIGIN      
        1 tttaaatggc taagttcatt ataaaatccg ccatattttt tcttttaagt aaaaaatata
       61 ggtgattttt tttgacttca tatttataat aaagacacgt aaatcaatta tttttcattt
      121 tactttaact aataatgttt atttggaggg attattatgt tagatgatag attgacgtgt
      181 tctaattgtg gtacattatt ttactatgag gaagttagaa atattgtaaa acatagaaaa
      241 aaagaaatgc ctatacgttg tccaaattgc aatgaagtta ttaagcgaaa gttgtctcat
      301 ggttattttg tcagctacga actatatgaa gaaagtaaaa taaatctgaa aaaaaaacca
      361 aaatactata aaaatttgaa aactggagct attataactg aaaaagaatt taaaaattta
      421 gtgactgaag aagaaagcag gttttataat ttgtctggta atatttgccc tggatttatg
      481 gatcagatta ttgaaaatga gtcaattgaa tcaattgaaa actatgttcc tgttgactta
      541 ccaaaataga aaaaataatc ctgtttttac agtgaattat tttaattttg attttcaata
      601 aaaatatatt acaataataa tcgtaatagc taatgaaaca atttctcaat ctttttacca
      661 ctccaaacag ggagcgtcaa taattttgtg taaataactc gtccttctgc aaaataatgg
      721 gttactcagt aaacattgaa gctaatgtat ccgtcacttg ttggaagcct ttatggcttc
      781 tatttaagaa tttttgattg tatgtatcaa agatggatac taggaaacgc tctagtgatt
      841 cttcattttg aaactgctct tttctgcggc tgtatttctt gatttgttta ttgaaagatt
      901 cgattgtaga accagaagga atggagaaca cttttgaact ttacaacaaa actactgttg
      961 ataaattaat tccaatttta gttccaactg atttaaatgg tcatgatgtt ttacttcgtt
     1021 ttaacggatt tttaggtgag gattatagat acctaaaaat ttctgatcct caacctttaa
     1081 cagaataata aaaaacgtgt aatcaattat ttgattacac gttttttatt tcaatcttcg
     1141 ttgtagtagt ggttgcgaca taccgaaagg taatcttcat tacctcctac tacaatctgt
     1201 tcacctgaat aaactggaat accatcaaca atacgagcat tcattacagc ctttttattg
     1261 caaaaatggc aaatagtttt aatttcctca attttatcag caaatgtcaa taatgcttcg
     1321 gatcccttga agagattatt ttgaaaatca ttcttcaatc catagcaaat tactggtact
     1381 tcctcattca ttacgataag tgatagatca ataatattct ctctacttaa aaattgagac
     1441 tcatcgacca aaatacaatc aacttttccg tactgatcaa taatctccac taattctccg
     1501 tacacatcca tttcagaagt aattgcaata gctggtttcg aaacacctat acgactctca
     1561 acttttccaa atcctgatcg agtatctatt gcgcttgtca ttatgataac tctcttccct
     1621 tgttcttcat aattatgagc cactttcagt agctcaatac tctttccact attcattgtt
     1681 ccatatctgt aaaataattg tgccattaaa tttattccct tcttttacaa ttcaattatt
     1741 ccttaattcc atctgctttt atgcagctgc tcgtttattc cttgatatgt ctataacatc
     1801 tactatccct aaaaccaatt tataagccat tagagatggt attcctgaac atctctcata
     1861 ttgttttttg agtggtatat catctgaaaa actgaaggaa tcatgaaaat agcgacatac
     1921 ttatcattta gagttctaac tttaaatgca tttacttctt cagtcagcac tttagtcatg
     1981 ttggacatgg tttggggcgt gtagtgatgc ccatacattt tctcaatcaa gtctgcgatt
     2041 tccgacatgg taataccttt tcggaagagg tgaatgacgg tctcctctaa tgtgtcattc
     2101 gtccgtctat aagcaggaac agtctgttgc ttgaactcgc cattgcggtc gcgcggaatc
     2161 tggagatgaa gttccccata ctcggtcttg accgtacggt cataggagcc gttacgagaa
     2221 ttacccgtgt taaaaccaat gcgatcgtac ttttcgtaat cgaggaaagc cgttaactcc
     2281 gttttgagaa gcgtattgac agctttttcc aaatggacac ggaataatcc attcaaatcg
     2341 cctttgttcg ctagagtctt taggatttct gtagtaaaat cgttcatatg gaagtcctct
     2401 tttctgtgaa tgtgttgtgg taactctatt ctacagaagg gacttc
//
LOCUS       DAFTHM010000178         2410 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFTHM010000178 DAFTHM010000000
VERSION     DAFTHM010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.183"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(246..467)
                     /locus_tag="L7C88_002769"
     CDS             complement(246..467)
                     /locus_tag="L7C88_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559544.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(565..810)
                     /locus_tag="L7C88_002770"
     CDS             complement(565..810)
                     /locus_tag="L7C88_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559545.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1050..1664
                     /locus_tag="L7C88_002771"
                     /pseudo
     CDS             1050..1664
                     /locus_tag="L7C88_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2034..2410)
                     /locus_tag="L7C88_002772"
                     /pseudo
     CDS             complement(2034..2410)
                     /locus_tag="L7C88_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
BASE COUNT          815 a          419 c          332 g          844 t
ORIGIN      
        1 tttactatat acttcttccc agaacttgtc cgtctccttc aaattatctc tacctctcga
       61 gttcattggg tggtttgccc atttattaaa catggaatca cctttctcat actcatatat
      121 ttatgtccta tttcaattat atttatatat gcttaaataa atttgtatcc tgaaatttat
      181 tgtaatatga agctgtattt tacatatagt aaccaaagag ttaataaaat aaaaagagcg
      241 aaccattata gatcagctct tttttcattg ctgtttttaa tcttatctag aatcacttca
      301 aatgtttcaa aggtatttac atctaactga cataaccaaa gcaagtactt cttttctttg
      361 taagtccaat caatattacg gtaagaggac attagattat ggtaccttgc tctttgttca
      421 actgaagcca attcccagcg tttttcaaat attttttctt cttccattat tgatccctcg
      481 caagacgcta cctcaaactt aaataatggg cagcgaaagt ctaattcctt agatctaagt
      541 atagcaaaca aatatgaaaa aaacttagaa ggtagtaaaa gttcttccgt cttttgcttt
      601 gcttctattc ttaatgtgtt tcgttatcgg tgccctacaa agattttcat taattacaca
      661 ctcatttatt gttgtgtatt ttctgacatt tctctcttga tcaattattt taattccatg
      721 ggcatcctga tagttcatag gagaggagcg gctatcagaa atagttgcac ctatctcttg
      781 aacttctttt acaacttctg gaaaatccat ccatcctgct tcagctgtca aaagtaataa
      841 tctataatat ttatctttcc ttttcaatct aagaaatcgt caccccattc tttttcttct
      901 attataaact atttaacttt tagaattcaa aaaccgtttg tctatttaga gtttacccta
      961 aatagacaaa aatataacat tgaaaaattt agagttctaa cgtatgatta gggtgtatta
     1021 taaacgttat agaaaagtag ggaataaatt tgaaaattgc ttatattaga gtttcatcca
     1081 tcgatcaaaa tgaacaacgt caaattgaag aaatgaaaaa gtttggcgct gaaaaaattt
     1141 ttatcgaaaa acaatctgga gcgacgatta gtcatcggcc gattttccag gaagctttag
     1201 attttgtcag agagcaagat atttttattg tagaagccat tgatcgactt ggacgcaatt
     1261 atgacgagat tatcgattca gtgaattatc taaagaagaa gaatgtgcga cttattatca
     1321 ccagtttacc gatcatggct gaagcaattg gaaatcctct cctagataaa ttcatcaaag
     1381 acttaatcat ttaaatctca gccatgattg ctgaacaaga acgtactgaa tcgaaacgac
     1441 gccaggcaca aggaattaaa atcgctaaag caaacggcgt ctataaaggt cgtcctaagt
     1501 tatacagtgc agacaccaaa gatcctcaac gtcgccttgt ctataggagt atcgttcagg
     1561 atcttgagaa tggggttgct atctcaaaga ttgcaacaga ctacaatgtg actaggcaaa
     1621 caatttaccg aataaaaaaa gaaatcgacc aactaattgt atgatttctt ttttgaatca
     1681 cgtaattatt aattagcttt gtcatcaata cagacaatca ttttagattc atctagctaa
     1741 gttgattaca tttatgttaa aaagaattta gttaacataa atataattga tgcataaatc
     1801 gtccttattt aaaggcattt aacattgaca acttagtata atgtatctta tgtaaactaa
     1861 taagatttga attttatttt atacacactc gataatagat caattttatg gtcccccgca
     1921 tttacgattg cacaagagaa acataaagtc gacctattag catttctttt caattcaaac
     1981 attaaaaaag tttatacctc tgctactaaa aaatgaaatt atctatttaa aatttaaaac
     2041 ggtaaatctg attcatccaa attggaaaat ggatcagcct gtattggagc tttgtatttc
     2101 tccataataa cagatatctt tttttcattt tttaaaaata ccttttaaat ttcttatagt
     2161 cctctgaaat caaaatatag cgtgatggat actcatcaaa agaagaatcg tattcttcct
     2221 ttaaaattcc cgatttactt aatttttcta gtacatcaaa tactctatca ctcaagtaac
     2281 tccttaaatt gttatcactt tcccattgaa ctacttttct ataagttgaa ttatcagttg
     2341 aaaagataga attttcatcc ataaacgcat atattagcag caatctttca tcattgtcaa
     2401 attctattgg
//
LOCUS       DAFTHM010000179         2407 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFTHM010000179 DAFTHM010000000
VERSION     DAFTHM010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.184"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            5..1150
                     /locus_tag="L7C88_002773"
     CDS             5..1150
                     /locus_tag="L7C88_002773"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBP9559546.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1321..1779
                     /locus_tag="L7C88_002774"
     CDS             1321..1779
                     /locus_tag="L7C88_002774"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBP9559547.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..>2407
                     /locus_tag="L7C88_002775"
     CDS             1938..>2407
                     /locus_tag="L7C88_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBP9559548.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          802 a          452 c          455 g          698 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgttagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccat aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttcttta
//
LOCUS       DAFTHM010000180         2398 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFTHM010000180 DAFTHM010000000
VERSION     DAFTHM010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.185"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            207..2069
                     /locus_tag="L7C88_002776"
     CDS             207..2069
                     /locus_tag="L7C88_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBP9559549.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="L7C88_002777"
     CDS             2069..>2398
                     /locus_tag="L7C88_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBP9559550.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAFTHM010000181         2334 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFTHM010000181 DAFTHM010000000
VERSION     DAFTHM010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.186"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            244..510
                     /locus_tag="L7C88_002778"
     CDS             244..510
                     /locus_tag="L7C88_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBP9559551.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            510..2237
                     /gene="ptsP"
                     /locus_tag="L7C88_002779"
     CDS             510..2237
                     /gene="ptsP"
                     /locus_tag="L7C88_002779"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBP9559552.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
BASE COUNT          820 a          390 c          516 g          608 t
ORIGIN      
        1 gaagagaaag cgacaagaaa aaggaaataa acacgtttgt tataaaatgt gaagaaaagg
       61 atgaaaaaga atccggaata atttgaatac ttttatctga aattgaatga aaactgttgt
      121 atctaacgaa aaaaaatgtt aatctttaca gatgaaaggg tggcatttgt taggattctc
      181 tgaattacta aaaaagaaaa ccctcacata aaaacaacac tcacttaaag gagaccgatt
      241 aatatggaaa agaaagaatt tcacgtagta gcagaaactg ggatccacgc tcgtccagct
      301 acactattag tacaaacagc aagcaaattt aactctgatg taaacttaga gtataaaggt
      361 aaatcagtaa acttgaaatc aatcatgggc gttatgtctt taggtgtagg tcaaggttct
      421 gatgttacta ttactgcaga aggtgctgac gaagctgatg caatggcagc aatcgttgaa
      481 acaatgaaga aagaaggctt atctgaataa tggttgaaat gctaaaaggg attgccgcta
      541 gtgacggtgt agccgttgca aaagcttacc tgctagttca accggattta acattcagta
      601 aggcaacagt agaagatact gcggctgaag aagctcgttt ggatgctgca ttagctaaat
      661 ctactgaaga attgcagcaa attcgtgaaa aagcagcgca aagcttaggt gaagcagaag
      721 cgcaagtatt tgatgcccat ttgatggttc tttcagatcc agaaatggta ggtcaaatca
      781 agcaaaatat taaagacaac agcgtaaatg ctgaatcagc gctaaaagaa gtaacggata
      841 tgtatatcgg tatgttcgaa gcaatggaag ataatgctta tatgcaagag cgtgctgcag
      901 atattcgtga cgttgctaaa cgtattttag cgcacttatt aggcgttact ttaccaaatc
      961 catcaatgat caacgaagaa gtggtcgttg ttgcacatga cttgactcca agtgatacag
     1021 cacaattaga tcgcaatttt gtaaaagcgt ttgtaacaga cattggtgga cgtacttcac
     1081 attctgctat catggcacgt tctttagaaa ttccagcaat cgttgggaca aaagaaatta
     1141 ctgctaaagt caaagaaggc gatattttgg ctgtcaacgg gatcgaaggc gatgtaatca
     1201 tcgatcctac agatgaacaa aaagctgaat ttgaaaaagc aggtgcagat tacgcagcac
     1261 aaaaagcaga atgggaaaaa ttaaaaaatg cagaaactgt cacagctgac ggcaagcatt
     1321 ttgaattagc tgcaaacatc ggaacaccaa aagatctagt tggtgtccat aataatggtg
     1381 gagaagcagt tggtctgtac cgtactgaat tcctgtatat ggattctcca gacttcccaa
     1441 cagaagatga ccaatatgaa gcttacaaag ctgtattaga aggtatggaa ggaaaacctg
     1501 tagttgttcg tacaatggac atcggtggag ataaagaact accatatctg caattacctc
     1561 atgaaatgaa tccattctta ggatatcgtg cattgcgtat cagtttatct gaacaaggcg
     1621 acgaaatgtt ccgtacacaa atgcgtgcat tgcttcgtgc atctgttcat ggtaatttac
     1681 gtatcatgtt ccctatggta gctacactca aagaattccg cgcagcaaaa gcgatctttg
     1741 aagaagaaaa acaaaaattg ataagtgaag gcaaggaagt atctgatacg atccaagtcg
     1801 gcatcatgat cgagattcca gcagcagcag tcttagcaga caagtttgca aaagaagtag
     1861 atttcttctc tgtaggtacg aacgatttga ttcaatacac aatggcagca gaccgtatga
     1921 acgaacgcgt ttcttacttg taccaaccat ataacccatc aattttacgt ttgatcaaaa
     1981 atgtaattga tgcagcacac gctgaaggaa aatgggcagg tatgtgtgga gaaatggctg
     2041 gagatcaaac agctgttcca ttgctagtag gtatgggtct agatgagttc tcaatgagtg
     2101 cgacatctat tcttaaaacg cgtagtttaa tgaaacgctt ggacacagcg aaaatggctg
     2161 aacttgctga tcgtgcattg aaagaatgcg atatgatgga agaagtcgtt gaacttgttc
     2221 atgaatatgt aaaataaaca acgtatcaaa agctggtgtg gcttgtaaaa gagctacgcc
     2281 agtttttttg ttctttttta agaaaacgtt tttgtcagta agaatagaca aaaa
//
LOCUS       DAFTHM010000182         2312 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFTHM010000182 DAFTHM010000000
VERSION     DAFTHM010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.187"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..508
                     /locus_tag="L7C88_002780"
     CDS             <1..508
                     /locus_tag="L7C88_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBP9559553.1"
                     /translation="VKLTDKDLDTAWKEFYPEVSTQIILFSTKEEADKAKKEANEGEN
                     FSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVSDIIPVTDPTTY
                     QQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRKVMKKDNVTIKD
                     PYVKNIFK"
     gene            complement(1092..1787)
                     /locus_tag="L7C88_002781"
     CDS             complement(1092..1787)
                     /locus_tag="L7C88_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBP9559554.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1771..2169)
                     /locus_tag="L7C88_002782"
     CDS             complement(1771..2169)
                     /locus_tag="L7C88_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBP9559555.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT          742 a          420 c          346 g          804 t
ORIGIN      
        1 tgtaaaatta acagataaag atctagacac tgcttggaaa gaattctatc cagaagttag
       61 tacacagatc attctatttt cgactaaaga agaagcagat aaagcaaaaa aagaagcaaa
      121 tgaaggggaa aatttctcca agcttgttca agcttatgga aaaaataaaa cattaaagga
      181 aactgatgga aaaatgaatt ttgattcaac caatccagag attcctactg aagtaaaaaa
      241 agcagcattt aaactaaaaa acggggaagt ttctgatatc attcctgtaa cagatccaac
      301 gacttatcag caaagctatt atctagtaaa aatggtaaaa aaacaggata aaggttctaa
      361 taaagacaaa tacaaatctg agctagaaaa aattgctacc gaagcaaaaa ctcttgatac
      421 ggaattcatg gataaaacaa tccgtaaagt gatgaaaaaa gacaatgtaa ctattaaaga
      481 tccttatgta aaaaatatat tcaaataaac aaatttgacc caattgggga tgtggcaaaa
      541 tttgagaagt gatttttgga aattccttct tatttttgag gcaaaccact tttgccacaa
      601 cttcatcggg gccttttttt atttgtacca aaacaaatca ctggatttgt tacaatcatg
      661 aggatataat ttaaaaaagt tttttatttc tatcacatga atcaatgcgc cattaagtag
      721 attctttcat gcttccctat tttttcactt gccgtatcgc ttcaaaaaca actatcataa
      781 actcaaactc gactgaaaag ttattttaaa aaagactaaa aatatccctt ctggacttgt
      841 tcctcttatt ctgttatact agagaaacac gaaagatatt tttatgcgac acttttcatt
      901 tgtttttatg aaatttattc aaaactggcg taacttcaga gttacaagga tgtattagag
      961 gttagggaat acatcgttta aatgagaaat aagtaatagt cacccaaact ttaaattaat
     1021 gaatattgaa tcgtcagata gcctcctcga gttttcgaga aggctatcgt ttattttatg
     1081 gagaaattga ttcagaagta atcagcgacc ttttttagtt caccaatcgt ttctgcttgg
     1141 aaagtttgca cccaatcttc ttggaagccc ctcactgctt tatcaatcga gggcatctct
     1201 aatacttgat ctagtagctc tttacctaac gttatcgcat gagctccaga tcgaatggct
     1261 gtagtgactt gttcacaatt tttgaaacta gctgctaata tttttgttgg tctttgcgta
     1321 cgttcgatct cagtccgcaa cgaatcaatc actttcatag catcaatgcc ttgattttgc
     1381 atcctgttat aataaggtgc aatataatct gctccattat taatagctaa atacccttgt
     1441 aattctgtgt aaatagctgt accggtaatc aaataacctt cttttttcaa ctttttgatc
     1501 gcttgaaggc ctgcttgatt caccggcacc ttgataaacg tatcttttcc cagttcttct
     1561 atgataactc gagcatcctc tatcatttct tcttccgttc ttcctattgt ctgaatatgg
     1621 ataggaatct gtccgattat ttttttgatt tctttcatat gcgagaagaa gtttgacgct
     1681 ccttcttttt tcagaattgt aggatttgtt gttacgcctg ttaaattcaa aaactgttga
     1741 caagaataaa tactttttgt atttgctgta tcaagcatga tttccatata gctttccccc
     1801 attctgatcc tcttgatcga ttttaatgat tgtccccttt cttaaatgcg gcatttcctt
     1861 atcttctaca tacattgttc ctggaagttc cggctcatga gatccatcaa attttatcgt
     1921 gatatgtcct aattcattca aattagtttg gacaacatct cctactgctg tgattacata
     1981 catttgttta tcaaaacaga gcttcatatc acaagttatt tcttttctta cctgattcaa
     2041 ttcaatctta taacaataat ctgttaatgt ttccggtgct tcatctccaa ataaaatcat
     2101 tattttttct ttcctgaata cttctgcttc tataccaaca tctgttacaa ccgtttcaaa
     2161 gatcgtcatc tctgttcctc ctcgtaaaat atcatttgtc taatagtttt tattcaaaat
     2221 gtttctagat tataaaattt attgaataac acattcctaa cggaatttgt ttcgatattg
     2281 tgtgatttct cagagtacaa tggatgtatg ga
//
LOCUS       DAFTHM010000183         2291 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFTHM010000183 DAFTHM010000000
VERSION     DAFTHM010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.188"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            126..1739
                     /locus_tag="L7C88_002783"
     CDS             126..1739
                     /locus_tag="L7C88_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBP9559556.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT          716 a          408 c          445 g          722 t
ORIGIN      
        1 ttttatccac aaattatttc tctatatttt ctgtctattc aaaataaaca ataattttcc
       61 ggcacaatta tttgctgttt tttaccataa catagtacga tcaacgtaga aaaggagatg
      121 tttttatgaa agttgttgtc attggcggtg tagctggcgg tccttcattt gccactcgtt
      181 tccgtcgatt gaatgaagcg cacgaaatca ttatctatga acgcggagaa aatatttctt
      241 atgcaagttg tgctttgcct tattatttag gaggtgtgat cactgaccgt gactcgctga
      301 tcgaacgtac accagaaata ttgaaaacaa aaaacaacat cgatgtcttt actaaacacg
      361 aagtaacagc aatcgatcct tctactaagc gattaacagt taaagaccta tccacaaatg
      421 aagaaataaa aacagattac gataagttga tcatctcttc tggtgctaga ccagattatc
      481 cggatattcc cggagttttt gaagcagaaa acggctttgt cctccgtagt gtgacggatg
      541 cggatcgaat caaatcgttc cttgaagaaa aaaatccaca acatgtcgtc attcttggtg
      601 caggtgttat gggtctggaa ttagctgaga atttcaagca tcgcggctta gacgtgactt
      661 taatcgatca attgccacaa gtcgctttcc cttatgatcc agaaattgct aatttagttt
      721 atgacaaatt gctgaaagaa ggattagccg ttcatttaga aacaagagtt actgagatcc
      781 gtgataaagg tcgagaaata gtattatcag atggctccgt cctttctgct gatatgctaa
      841 tttttgctgt tggtgtttct ccgaagaatg aagtggtgaa agcaaccggc atacaattat
      901 cagatacagg tcagatcatt gttgatgacc agttacaaac caatctgccg gacatctatg
      961 cgattggcga tattatcgaa acgactagtg tagtgactgg tcagccgatc caaagtatgc
     1021 tttccagtgc ggccaatcgt caaggacata tgctggcaga tattttaaat ggtacgccta
     1081 tgcgctatcg cggatatatt ggtgcaggtg tcgcaaaaat ctttgatcat acagcaagtt
     1141 atgcgggaat gacagaacat gaattaaaag catcaggcat aacaaattat aaaactgttt
     1201 ttatcactcc ctttgaccat gcctatttct atccagaagc tacaagatta aatctaaagc
     1261 tgatttttga tgcagatagc ggtcgtattt taggtggaca agcatttgga gaaaaaggtg
     1321 tcgataaacg gatgggagaa ctttctgtag caatcaccgg aaacttgaca gtctttgatt
     1381 tgcctgattt ggagttgcct tactctccac cgtattctac tacccgtgac ccgttgaata
     1441 tagctggtta tgtcgcaatc aatcaaatga cgaatatcgt agaaacgatc aaagcaagtg
     1501 atatacccga aaacgatttg aaagaagcgt tctttttaga tatacgtgaa cctaataaag
     1561 caccttctgg cagtatctcg gcaacaaaaa atattccaat gaatgagtta cgagatcgaa
     1621 tcaatgaaat cccaaaagat aaaaaagttt acattacttt cagaagagga ttgaatactt
     1681 atacttctgc ccgaatcttg gcaggtttgg gtatcaaagc gattttgatt gaagaataaa
     1741 aaaacgaccg cggtgggtag ccgcggtcta ggagttattt ttacttgagg agtaaaaatg
     1801 aaaaagtata tagggttgtt ggttggtatg tatatagaat agaagataaa tgtgaagaaa
     1861 ttgtgcatta tttcttcaca tttattaggt tatagtttaa gaaagtttaa acattgcgca
     1921 atttaattat tttagctgtt tcttttcata aaaaaacatg ttgtgactct gagacaaatc
     1981 atagtccata gtgatgtctc tagagtaact acgcctaata ttacgaggca tcatattaat
     2041 ctatcagcac tagtacctaa actagcatcc ctttcgaata ttttttctta tataataaag
     2101 tttgctttca ctcctctaat ctcaccaaat cgactggctt gcgttgtgtg atactaggaa
     2161 ctgattggtt tagaacgact tttctattgt aatcatattt ttcgccatcc tcgttgtctt
     2221 ctaatccttc aatgaatgat ccctaatgtg tgtattaaat aatttaattt ttttgttcct
     2281 atttatttaa c
//
LOCUS       DAFTHM010000184         2282 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFTHM010000184 DAFTHM010000000
VERSION     DAFTHM010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.189"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(262..624)
                     /locus_tag="L7C88_002784"
     CDS             complement(262..624)
                     /locus_tag="L7C88_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559557.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPDESDGLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(628..966)
                     /locus_tag="L7C88_002785"
     CDS             complement(628..966)
                     /locus_tag="L7C88_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559558.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERIMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            complement(945..1364)
                     /locus_tag="L7C88_002786"
     CDS             complement(945..1364)
                     /locus_tag="L7C88_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559559.1"
                     /translation="MTDLSEKMTIKNLADELGVSKNTVRNQLVNSGFDLAQYKENGII
                     MLDKELIGVVRSIYRSKSDQLTGQLPVNNTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(1357..1590)
                     /locus_tag="L7C88_002787"
     CDS             complement(1357..1590)
                     /locus_tag="L7C88_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559560.1"
                     /translation="MTEKQKYFGKKNWLVNLTGDYVVVVFLDSKKMSGKLLDVTQYEL
                     ILKNNKIDSPIIIPKHAVKYIYAVAESSGEAND"
     gene            complement(1587..>2282)
                     /locus_tag="L7C88_002788"
     CDS             complement(1587..>2282)
                     /locus_tag="L7C88_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBP9559561.1"
                     /translation="IAYIEILKWQEGKGRIDFNPNKISQFLASSMKNFIHDLFIEPHF
                     SRADIACDIIDVPDEFITQYRVVDPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKK
                     LEQERKRKIVPPEITTWWRLELQLRRGKATDWHEMVHESLDSFASPHYFPPNTKVTER
                     IMVKGLLYDHSEWGNLAKNTKKKYRDLLKQESQNDELTNHLRETFAESADDLKKELDT
                     WLLGLDVTEEEEK"
BASE COUNT          650 a          513 c          317 g          802 t
ORIGIN      
        1 gtattctttg ttcccttttt gaacgaaata ctgaacccca agttaaaacc ctccttcggc
       61 tgtcgctaat aaaaagagtg taaacctttc tgttactctt tgtcaaagag taacattttc
      121 ctaattgtga catggctgtc acaattccaa atgctctccg agggtattcg ctgtcacaag
      181 tgacaacgaa aaaaggagcc gaaagcgtgt cacgctctca actcctttta cgctttattt
      241 tgcttcacgc aaaataatcg cttatcgtaa attcacgtca ttaaatattg acgtaaattt
      301 actctcactc atctgacttt tcttattcgg tatcactccg aataagccgt cagattcatc
      361 gggataatct cgttcgcttg gcgctgattt ttcatcagca agccactcat tatccactga
      421 tttttcgtgt tgctgatcgt cagaaatcga cgatagccac cgctcaaaat cagcaaaagt
      481 ttcaaaccca aaacgcttcc gaagagcctt gcccattgca gcattttctt tctcaatcaa
      541 gcgttttttc tgttggcgaa gtttcgcttg ttcttttttt aatttttctt cttgcgcttt
      601 aatatctgct aaagtcattc ccataaacta catctccttt tctttggaat taataacgga
      661 aatttggttt aactgcataa catgactcat taatttcaac caaaattctt tttctgattc
      721 atcagttgtt tgcgctaaat gcttatgaac aaattcatta gtcaaaactg aagattttgc
      781 taaatcagca ttgataaccg agttgagaac atccataatt cgttcaagca tttcactata
      841 attatcttca tccggcaaat tcaaataatc agctaaccgt tcatacatca attcaattct
      901 atcgactgtt tcttctctca aatcaatttt atccatgtca cacctcactt ccagaattgc
      961 caccattttc gattttttaa ttcttgattt tctagtaaca actgatcgtt tttttgttgc
     1021 tgaagcaggg tcaatttttg ttgatcacga atcatttctg ttaattcaga aatatgtttg
     1081 tccttctcag ctaattgatc acgcaaaaac tcattctctt tttctaaagg aaaatcactg
     1141 cctgtgttat tgaccggtaa ttgaccagtc aattgatcac tttttgaccg ataaattgac
     1201 cgaacaacac caatcaactc tttatctagc atgataatgc cattttcttt atactgagca
     1261 aggtcaaacc ctgaattgac cagttgattg cgcactgtat ttttcgatac acccaattcg
     1321 tcagcaagat tttttatggt catcttttct gacaaatcag tcattagctt ctccactact
     1381 ttcagctacc gcataaatat atttaacggc gtgcttaggg ataataatcg gagagtcaat
     1441 tttattattt ttcaaaatca attcatattg cgttacatca agtaacttac cggacatttt
     1501 tttgctatcc aaaaaaacaa ccacaacgta atcacctgtt aaatttacca accaattttt
     1561 cttaccaaaa tacttttgtt tttctgtcat ttttcttcct cctctgttac gtctagccct
     1621 agaagccatg tgtctaattc tttttttaaa tcgtctgccg attccgcaaa ggtttctcgc
     1681 aaatgattcg tcaattcatc attttgactt tcttgcttca acaaatccct gtattttttc
     1741 tttgtattct tagctagatt tccccactca gaatgatcat aaagcaaacc tttcaccata
     1801 atccgttcag taactttagt atttggcgga aaataatgtg gactagcaaa gctatccaaa
     1861 ctttcatgaa ccatctcatg ccaatcagtt gcttttcccc ttcgtaactg caattctagt
     1921 cgccaccatg tcgttatttc cggcggaaca attttacgtt ttctttcttg ttccagtttt
     1981 ttattataca tccgaatttg tcgttcactg gcacgactac cccaatatgc cgtttctaac
     2041 ttaccagaac gcccataaat tggtttaaaa gacacaggat caactacccg atattgtgta
     2101 ataaactcat caggtacatc gataatgtcg caagcaatat ccgcacgtga aaagtgaggt
     2161 tcgataaaca aatcatgaat aaaatttttc atggaactag ctaagaattg actaatctta
     2221 ttcggattga agtctatacg ccctttcccc tcttgccatt ttaaaatttc aatataagca
     2281 at
//
LOCUS       DAFTHM010000185         2243 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFTHM010000185 DAFTHM010000000
VERSION     DAFTHM010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.190"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..318
                     /locus_tag="L7C88_002789"
     CDS             <1..318
                     /locus_tag="L7C88_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9559562.1"
                     /translation="KAIIPENLDEVKLYLWEDNGEIVGFSGVSAEELVMLFLDPDFIG
                     KRYGSQILIELIETEDIKRIDVNSQNKYAKHFYLSHGFEIESEEDLDGFGKPYPITHL
                     VKK"
     gene            732..1550
                     /locus_tag="L7C88_002790"
     CDS             732..1550
                     /locus_tag="L7C88_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBP9559563.1"
                     /translation="MNKNPHNLKLVAVDMDGTFARTDYTYDIPRFKAVLSRMKAVDCQ
                     FVVASGNQYYQLRSLFPNYYDELSFVAENGAFVKDKTEVLFSADMPRKAIEVVLDLCK
                     DYPEVKNVMCGLNSAYCERGKVSQAFFDLTNIYYHRLEWVADFAEVQDKILKFAPTMP
                     VEKTEFYVELFREKLAGLLVPTSSGHGSVDLILSECHKTFGLKMLVERLGINPDQCVA
                     FGDGGNDIEMLEYCGLSYEMDNATEAVKQVAKHQCPSNDEDGVLVTLDRLFPNT"
     gene            complement(1623..1982)
                     /locus_tag="L7C88_002791"
     CDS             complement(1623..1982)
                     /locus_tag="L7C88_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBP9559564.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
BASE COUNT          755 a          325 c          416 g          747 t
ORIGIN      
        1 aaagcaatca ttcctgagaa cttagatgag gttaaacttt atttatggga agataacgga
       61 gaaattgtcg gttttagtgg tgtaagtgca gaagaattag ttatgctatt tcttgatcca
      121 gattttattg gtaagcgata tggtagtcaa atattaattg agctgattga aactgaagat
      181 ataaaaagaa ttgatgttaa tagtcaaaat aaatatgcaa aacattttta tttaagccat
      241 ggatttgaaa ttgaatctga agaagactta gatggttttg gtaaaccata ccctataacg
      301 catttagtaa aaaaataatt catgaatggt ttattacctg attgaacatg aataaaagta
      361 atatttttat tttgatggcc tatttctagg ttatgaatta tccagatcaa atttgtgtat
      421 tacattcagt aataaggtgc ttatcttagg atcaacttat gatactagct gaccaaggat
      481 gtaccagtta tagaaaatca gttaaagtaa aaatgataaa aatcttatgt caacactgat
      541 ttaggctgac ctgtgggtta ggagaaagac aggtcggtag cttttaatac aaaaaatggc
      601 ttgtatgtat ctagatagtt aactgaaatt agaaatgttc ttatttttaa cggagtaaga
      661 aaaataggct gctttaggtc tgaatacttt ttcaatataa tgaagatatc aaaggcgaca
      721 ggagtgtttt tatgaataag aatcctcata atctaaagtt ggtagcagta gatatggatg
      781 gaacatttgc tcgtactgat tacacatacg atatcccaag gttcaaggct gttttatcgc
      841 gaatgaaagc tgttgattgt caatttgttg ttgcaagtgg aaatcaatac taccaattga
      901 gatcgttatt tccaaattat tatgatgaat taagttttgt tgctgaaaat ggtgcttttg
      961 ttaaagataa aacagaggta ctattttcag ccgatatgcc tagaaaagcg atcgaggtgg
     1021 tccttgattt atgtaaagac tatcctgaag taaaaaatgt gatgtgtggt ctgaatagtg
     1081 cctactgtga aagaggaaag gtgagtcaag cattttttga tctaaccaat atctattacc
     1141 atagattaga atgggtagct gattttgcag aagttcaaga taaaatttta aaatttgctc
     1201 cgactatgcc tgttgaaaaa accgaatttt acgttgaatt gttccgtgaa aaattagccg
     1261 ggctattagt acctaccagt agtggtcatg gttctgtaga cttgattctt tctgagtgcc
     1321 ataaaacttt cggcttgaaa atgttagttg agcgcttggg gattaatcct gaccagtgcg
     1381 ttgcttttgg agatgggggc aatgacattg agatgttgga gtattgtggt ctgagttatg
     1441 aaatggataa tgcaacggaa gctgttaagc aagttgctaa gcatcaatgt ccttcaaatg
     1501 acgaagacgg tgttttagtg acgctcgatc gattgttccc taacacgtaa acactaggta
     1561 attcatcaaa aaacctcgat ataagaaata ttcgaggttt taaaactata tttagaacag
     1621 atttacgaag cgtctgatga gtcaaaatag acttggacat tgctatctaa aataccactt
     1681 tcattcttta aacgaattgt ttgatttgat ggagttacct ctaatactaa atgcccatta
     1741 ataaaggtag tatcgtattc agatgtttta actgttgctt cttcgcaagg tattgttaaa
     1801 tcatatgctg gaatataatg ttgtgtggaa actaataaaa aatgatcacc aatcatacag
     1861 catccctctg ctgaagaaaa ttgattagag ccatcattta aagttaacaa gaatccatcc
     1921 tttaaacgag gtacttgctt aaatacttct ggttgtactt ctaaaaataa attatcgctc
     1981 attttcacga ccaccatcga cttccacagt tgaaattgac attttattta acacacctat
     2041 tcccccttaa ctataactca attctatata aaaaatattc tattctcaaa taattgaact
     2101 tttcaaatcg ccaatttact tcggctttat cagagctcat tcatatcaag agcgattaac
     2161 gctgtaaaaa ttaaaccgaa gatctgataa attttctcta ttttctacaa tatttaaaac
     2221 gcttccttag tctattatat atc
//
LOCUS       DAFTHM010000186         2109 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFTHM010000186 DAFTHM010000000
VERSION     DAFTHM010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.191"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(138..1478)
                     /gene="glnA"
                     /locus_tag="L7C88_002792"
     CDS             complement(138..1478)
                     /gene="glnA"
                     /locus_tag="L7C88_002792"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBP9559565.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(1506..1898)
                     /locus_tag="L7C88_002793"
     CDS             complement(1506..1898)
                     /locus_tag="L7C88_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBP9559566.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT          603 a          466 c          356 g          684 t
ORIGIN      
        1 taaacggtgt tcaatcagct gaccctcggt attagctcaa aaaacggcaa aatatgagga
       61 actatttttc cgttagtttc tctaatactc aggtcaaaac gctgatttca cagcctctaa
      121 ttcacggtat tcctgtttta ataaagttct agatattgtt ctctttccca ctcggaaaca
      181 gtttgtctga atgccgccca ttcgagacgt tttgcttcaa caaaatttga gaagatatgt
      241 tgtcctaatg cgtcaatcat tacattatcc ttacgcaatt ctttgatagc attatggata
      301 gttgaaggta agtcctggat atgtgcagct tctctttctt cctcatccat tacataaatg
      361 ttacggtcaa cagctgctgg cggtgtgatc tgattacgga taccgtctag tcctgcttgc
      421 aacaatactg ccattgccaa gtatgggttt gcagatggat caactgaccg caattccaaa
      481 cgtgtggata aaccgcgaga ttctggtaca cgtactaatg gcgaacgatt acggccactc
      541 catgcgacat aaacaggcgc ttcataacct ggaacgagac gtttataaga attgactgtt
      601 ggattgcaaa cggctgtgta ggcacgagca tgtttcagca aaccacctaa gaaatgataa
      661 gctgtttcac ttagttccaa ttcaccgtct ttatcataga aaacatttcc ttcatcattg
      721 aacaaagaca tattgcaatg cataccagaa ccattgatcc caaataacgg tttcggcatg
      781 aaagtcgcgt gaagtccatg cttgcgtgca atcgttttga caacgagctt gaaggtttgg
      841 atattatcac aagcatctac cacatctgca tatttaaagt caatttcatg ctgtcctggc
      901 gctacttcat gatgtgaagc ttccacttca aagcctagac tttctaattc caacacgatg
      961 tcacggcggc aattttcacc taaatctgtt ggtgcaaaat caaaataacc acctttatca
     1021 ttcaaggtcg ttgtgatccc accgtcttcg tctaatttaa ataagaagaa ttctggttca
     1081 ggtcctaaat tgaaagaggt aaaaccaagg tcgcgcatat ctttcaatgc tcgtttcaaa
     1141 ttcccgcgag gatcgccggc aaatggtgtc ccatccggat tatagatatc acaaattaaa
     1201 cgagcaactt ttccatgagc actttcccac gggaagatca tccaagtgga gagatctgga
     1261 tacaaataca tatcgctttc ttcaattcga acaaatcctt caatcgaaga accgtcaaac
     1321 atcattttat tttctaatac tttgtcgatc tggctcactg gaacttctac atttttgatc
     1381 gtacctaaga tgtctgtgaa catcaatcgt aaaaatcgta cgttttcttc ctcaatgatt
     1441 cgtttgattt cttcacctgt tatctgtttc tttaccatgg tatccctctt ccttttttaa
     1501 tttattcagt caaagaattg tctttgcaat ccttgcgact gataatgacc tgttttgctt
     1561 aacccacctt gcgccaaaat ctcatcacga aaaatttgtc gaacgtcatg atctgtcaac
     1621 ggcttcttgt tttttgcttc ttgttttttc gcctgtgcca tttcgtatac acgtttgatc
     1681 ccagccatat tcaatccctc tgaaagatag tctttaatct caagcaacat atcaatatca
     1741 ttcagcgaat acatacgtcg gtttccttcg cttcgttccg gatgaactaa atcttgttct
     1801 tcataatagc gaatttgccg agcagacaaa tcagtcagct tcataactgt accaattgga
     1861 aatacggaca tagatcggcg caattccttt tctcccatca gacgtcccct ttcgttttat
     1921 aagttggcta aagtgtacca attaaaaaaa atattgtcaa ctgcatatgt taggttttct
     1981 aacatgagat ctctattttt tataaaataa caaaaaaata agaacacaaa aaaggtatct
     2041 agttgatttt cgtaccagat accttttatt ttttattata ctgtactatc ctttattagt
     2101 gtttttatt
//
LOCUS       DAFTHM010000187         2104 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFTHM010000187 DAFTHM010000000
VERSION     DAFTHM010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2104
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.192"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            169..1539
                     /locus_tag="L7C88_002794"
     CDS             169..1539
                     /locus_tag="L7C88_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4357 domain-containing protein"
                     /protein_id="HBP9559567.1"
                     /translation="MMDKSNEEQTTLYTKYWRRLEEVFDNSKGMEDFFRYYLAAITGE
                     YSAKHILYQAFKDYWHKERDVSSDAELLQKLVRYAGYFARLYYNKPEGKYSEVLSDFQ
                     SMESMMPAPFVLGLSEWYYHDQFITEDQYIDAIKVVNDYQLRRYFNGDDTSRVSKAFP
                     SYLKSVRKYAKANGYENIVDIVIYVLVTRNQSNNMALPSDKALKSNLLNANAYAMRLA
                     RWLLEKIENRENSATLDMSNLSIEHIMPQTSTSYWEEKAGTSGEEYTGLVNTIGNLTL
                     VTNPDNSAAGNKDFETKKKIFEDTLHIRMNKDLYELTEWTSSDISARSEALINELITM
                     YPYLRSSGDYEHDGNREIFLEAQGIKATGYLNEDETVIIHSGSEIYSKIKDIASDSLD
                     ETRQELLDNGIIEETIGGLQFVQDYTASSVSNAAALLLGGSRNGWDYWKYDNGISIND
                     SLRNKK"
     gene            1560..1844
                     /locus_tag="L7C88_002795"
     CDS             1560..1844
                     /locus_tag="L7C88_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559568.1"
                     /translation="MDKNKLRYAILKLRDEKKNPFIELKGQVPEEDILEQTKFLSRNG
                     LLESMVWADNTVHIWGSVSLEGEKYLVENSGLAKAYALAKEVKNWIPFWG"
BASE COUNT          731 a          308 c          444 g          621 t
ORIGIN      
        1 ttgatttacc aacatgttta gacattttcc tctaggaaaa aattaactag caccacgcgt
       61 attgtttata ttaaattaga tgaccgtgat aatgcacagc aaatttttga aagtatcaat
      121 tctaccggtg aaagattgac tgcctcggat ttgattcgaa acttcatcat gatggataaa
      181 tctaatgaag agcagactac gctttatact aaatattggc gtaggttgga agaagtcttt
      241 gataattcta aaggaatgga agactttttc agatactacc ttgctgcaat aactggggag
      301 tattcagcaa agcatattct ttatcaagca ttcaaagact attggcataa agagcgcgat
      361 gtatcaagtg atgccgaatt gctccaaaaa ttagtgcgat atgctggtta ttttgcgaga
      421 ctttactata acaaacctga aggaaaatac tcagaagtat tgagcgattt ccaaagtatg
      481 gaaagtatga tgcctgcacc ttttgttttg ggattatctg aatggtacta tcatgaccaa
      541 tttatcactg aagaccaata tattgatgcg attaaggtag tgaatgatta tcagcttagg
      601 agatatttta atggggatga tacaagcaga gtgtcaaaag catttccttc atatttgaaa
      661 agtgttagga agtacgctaa agctaatgga tatgaaaata tcgttgatat tgtaatttat
      721 gttcttgtta ctagaaatca atcaaataat atggcacttc catctgacaa ggcattgaaa
      781 tctaatctat tgaatgccaa tgcttatgcg atgagattgg cccgttggtt acttgaaaaa
      841 atagagaatc gagaaaattc agcaacactt gatatgagta acttgtccat tgaacacatc
      901 atgccacaga ctagtacttc atattgggaa gagaaggctg gtacatcggg ggaagaatac
      961 acaggattag taaataccat tggtaattta acactcgtta caaatcctga taattcggcc
     1021 gcgggaaata aagactttga gaccaaaaag aaaatctttg aagataccct tcatattcgt
     1081 atgaataaag atttgtacga attgactgag tggacatcat cggatatttc tgccagaagt
     1141 gaagctctaa tcaatgaact gattactatg tatccctatt tgagatcgtc gggcgactat
     1201 gaacacgatg ggaataggga aattttctta gaggcgcaag gaataaaagc aactgggtat
     1261 ttgaacgaag acgagaccgt gattatacat tcaggttcag aaatttattc taagattaaa
     1321 gatattgcat ctgattcgct agatgaaact cgccaagagc tgttggataa tggaatcatt
     1381 gaagaaacaa ttgggggact acaatttgtt caagattaca ctgcctcatc tgtttcgaat
     1441 gcagcagctc tgctattagg gggtagccgg aatggttggg actactggaa atatgataac
     1501 ggaataagta ttaatgattc gctaagaaat aagaaataga gcatagaggt ggtgttaggt
     1561 tggataagaa caaactaaga tatgcaattc ttaaattgcg tgatgaaaaa aagaatcctt
     1621 ttattgagct taaagggcaa gttccagaag aagatatttt agaacaaact aaatttcttt
     1681 cgcgcaatgg cttactagaa tccatggttt gggcggataa cactgttcat atctggggga
     1741 gtgtttctct ggaaggggaa aaatatttag ttgaaaactc aggtcttgct aaggcgtatg
     1801 cattggcaaa agaagttaaa aattggattc cattttgggg ctaagataag tttttaaacg
     1861 gagaaggtag caaatcataa ttggtttgtt gccttttttg attgcccaaa aagaaaaatg
     1921 acaaagtata gagataaatg acatagtaca cgggaaaaat gacattgtat caccgacaac
     1981 gtctaaatag atgttgatat atatacgttc cgtacaaata attataaaaa tttaaatgat
     2041 ttgagtagaa gtatcagtga atatctcaag gggaatagct atctcaagat tcgattttca
     2101 cata
//
LOCUS       DAFTHM010000188         2051 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFTHM010000188 DAFTHM010000000
VERSION     DAFTHM010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.193"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..337)
                     /locus_tag="L7C88_002796"
     CDS             complement(<1..337)
                     /locus_tag="L7C88_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBP9559569.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAK"
     gene            complement(404..559)
                     /locus_tag="L7C88_002797"
     CDS             complement(404..559)
                     /locus_tag="L7C88_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBP9559570.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
     gene            1169..1390
                     /locus_tag="L7C88_002798"
     CDS             1169..1390
                     /locus_tag="L7C88_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559571.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            1391..1648
                     /locus_tag="L7C88_002799"
     CDS             1391..1648
                     /locus_tag="L7C88_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559572.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1784..>2051)
                     /locus_tag="L7C88_002800"
     CDS             complement(1784..>2051)
                     /locus_tag="L7C88_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBP9559573.1"
                     /translation="SDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDL
                     IDYAMSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
BASE COUNT          675 a          460 c          313 g          603 t
ORIGIN      
        1 ttttagcata ttgaaatttt tctggattat ccatatgagc aaaatatcgc accatacctt
       61 ttgcattagc acatttttgc gggtttggag accgaagctt ttgagttatc tcacgtattt
      121 gatcatacgt ctttttaccg ctaaacatta tcaaaacatg ccaatgaggc tttttcaatt
      181 caccgtcagg attcacatct ttatcatgaa gtggactctc aacccaagga acatgtaact
      241 catctaaaaa ctccctccaa ttttcaggag ccgattcagg atagactaca aacgtccaat
      301 tccttgtgcg ttcatcttta gtttttctac tcgtcatgct ataattacct taattgaaca
      361 acagtctaac agcaaaagca gtgcgccaac actaatgctt ttgctatttt ttttgctcat
      421 tttcctttcc gttagcatta acccaaattg taataagacc agacttacta agacccattt
      481 gtttcgcaat tttatcaaga ttatctgcca cttccttagt aagcgttaca acgactctct
      541 ttttttcatt actgatcata attcgtatcc tccaacgact ttttcttaaa aaccatagta
      601 acaaaaaagt aactaaggtg caacagttta gatactaatt agcgaataat aggccttaaa
      661 cccttggcat tactgatttt gtcaaaaaaa aacgctgaaa cccttgggag agtaaggcta
      721 aacagctatc gaccaatgac caataagggg ggtgtcgtag tccccccctc ctccgcccaa
      781 ttcataaaca ccaaaaccaa aaaacaaacc tcagggctcc gccccgaacc ccgacctcct
      841 tctaccgaaa tatatgcagg cgccacgctt actatttcgt tcagctatcg gcttttgcaa
      901 tctaacacga ccgtttcgct accagtcgcc ttacaggctc cattctcgct tctcttacgt
      961 gttttaacga ttgcgccgat aactaaacga aatagacgct aaatcgctta aaacgcaaaa
     1021 tagacccttt ttagagcatt gattttttct actagtcatt tcgataatat aaaattgacc
     1081 acaacacaga aaacttatat tataagctta tgtcgtaagt ccgacgtact cacgtaatat
     1141 agacggacgt taaatggaag gagcataaat gagagtgata aaatcagaaa aattcacttt
     1201 ggccgaaatt atgacgacca gcgaacttgc acaagaactt gattacaacc aagcttacgt
     1261 tttgcgctta gcgaaagaac atctgactga aggaaaagaa tatcgctctg ccggtagaag
     1321 aaactatctt ttcagcccag aagcccttaa aaaactagaa aaagtcataa ccaccaaaga
     1381 aggtgagtaa atgcctaaag aaacaactat caacgttgaa caactagaaa aattgctaga
     1441 atcatattcc aatgatttta tcgaattgac cggcggaaaa gtcgaagaaa ccaccgacct
     1501 ctttgaccta cttctcacaa atattctgga attaaactct gaagaacaaa aagagcataa
     1561 gggaaaactg atagcacctt cctacaggaa ggtggctaag tcggctgtgc caactggttt
     1621 tcttacaaaa caaccttata ttttttgata tcacaaaaaa atccattttg gacctatttt
     1681 cggtcataat atagtaccta cttttggtca tagtttcgtc cgtagttttg gtcatagtga
     1741 ctaagacttt cacgcacaaa aaaagagctg aaattaacag ctcttatcct ttatttattt
     1801 ttgaatttac acttccacca tgacgattcg attttatata ttgcccgata atataagctg
     1861 aattatcaca aagaagcgga aaccaatcat caaatctttc tgacattgca tagtcaatta
     1921 aatctttgat ttcagtgata ttcttagaat caacaaacga catcatctct ctaatcaact
     1981 catatcgttc tgcactcgtt actgacaaat aactagcaat ttctgcacca ccatgagcga
     2041 taatatcact t
//
LOCUS       DAFTHM010000189         2042 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFTHM010000189 DAFTHM010000000
VERSION     DAFTHM010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2042
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.194"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            803..1276
                     /locus_tag="L7C88_002801"
     CDS             803..1276
                     /locus_tag="L7C88_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBP9559574.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1285..1512
                     /locus_tag="L7C88_002802"
     CDS             1285..1512
                     /locus_tag="L7C88_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9559575.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          660 a          328 c          306 g          748 t
ORIGIN      
        1 attgtactat tcattgatca taacgattgg ctatttgatt gtatcaaatc taggaaatat
       61 ggtatttggt atcagtaaag aattcagttg gactactaca ttatgggaat ctctattctt
      121 tttcatcttc gtatttttgt tacaaaatta tcgaaaaaaa taaacatgtg ccatctatct
      181 gttggcacat gttttaggat ttatggtact ttttattcgg caatccattt tatttttcta
      241 cttcttctta atacctctaa cacttttgat ttataaacta atccaatgca tctacttgcg
      301 cttattaagc tatttcagct agatagtacc accccatgcg tcaatgcttg attttccttt
      361 tgtataacat tgtataagca ataaaggaca aataagtggt gattacacca aaccattgaa
      421 taagaaaaat tctgatacgt aaataaacat gaacttgaaa aaattaatga atcggttagc
      481 tactacgtag ttgtcttttt tctcatacag ttctgttaac ttacacttct cttcgctaga
      541 taataaaaaa tcctccaact gtattgtcca atataatccc aggcatctaa actagcatta
      601 tagaagagac acacatagaa tctaaaataa ctggttttaa atgtttctta caatcaaaaa
      661 aagctgttaa atgcactcca caccttcata ctctatcatt ttttataaac gatatatttt
      721 tattgttttt cgataaaaaa tagttgtttt acaataatta ttctgctata ttttagctat
      781 caaagataaa agagggataa aaatgaaatt taaaacattg ctattaaaat ttgtcgtttt
      841 aggtataagt gccgtattta ttttgttcgg cgtacttttt tatactcaga tcgctacaag
      901 cgaaaaagga ttcaattttg attggcagac cacattattt gtttctgtca tttactttgc
      961 ccttctccta gggatcgtta ttgcttattt cttattgaaa ctattgaaaa aaatcgaaga
     1021 taaccaagct ttttccactc aaagcttaaa catactaaaa aaaatcgaac gaaccatttt
     1081 gtttattggt ttcgcctttt ttggcttact tcctaaattt atgaaagtag cggatttaga
     1141 cgatgctcca ggtttgatgt tggtaggaat cgctgtcgta ttcattcctt ttgcagtata
     1201 cacattaaca agcgtgctgg aaaaactgct tgaacatgcg attttactta agacagatca
     1261 tgatttgaca gtgtgaggtg cgacatggca attatcgtta atttagatgt agtattagct
     1321 caaaaaaaaa tgagtgtgac tgaattgagt gagaaagtgg gcattacgat ggcaaacatc
     1381 tctattctaa aaaatggaaa agcaaaagcc atccgttttt ccactctcga aaaaatctgc
     1441 caagttttgg agtgtcaacc aggtgatttg ttgacctata aaaatgactc gaatactata
     1501 ccagaagaat aaaataaagt agaacaaaca gtaaataaaa aataatctga atgatagatg
     1561 tgtgagactt ttagaagtta tttacgtcta ttattcagat tttttatttc gattgaatac
     1621 cgttttatct ataaataaga tatgtactga ctcatacaaa gggggccttt tcttctccat
     1681 gtactatcac ttttcctgat acaactggtt tcctgttacg ttgtagttgg atctgctttt
     1741 agtataatac tttattcatt ccaccagact gatagcagtt tgagcagtct aaataatcat
     1801 gtagtattac aggccattct gtttcatacc ttgaagtgct taaaacttca gctaatggcc
     1861 cattgtgtta actcttactc cattcttttt tagtaagctc ccatatatac tgtaaagcct
     1921 tctatatatt atgtcatgtt gctttttaac atttactatg tagttttgat aaaatgattt
     1981 gaataacagt gatggacaat tcttttttat ttttaacatt attttgataa taatgattat
     2041 tt
//
LOCUS       DAFTHM010000190         2003 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFTHM010000190 DAFTHM010000000
VERSION     DAFTHM010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.195"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..378
                     /locus_tag="L7C88_002803"
     CDS             <1..378
                     /locus_tag="L7C88_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBP9559576.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="L7C88_002804"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="L7C88_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBP9559577.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2003
                     /locus_tag="L7C88_002805"
     CDS             1859..>2003
                     /locus_tag="L7C88_002805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559578.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          555 a          339 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt tta
//
LOCUS       DAFTHM010000191         1985 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFTHM010000191 DAFTHM010000000
VERSION     DAFTHM010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.196"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            96..1475
                     /locus_tag="L7C88_002806"
     CDS             96..1475
                     /locus_tag="L7C88_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBP9559579.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            1756..1985
                     /locus_tag="L7C88_002807"
                     /pseudo
     CDS             1756..1985
                     /locus_tag="L7C88_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          705 a          338 c          421 g          521 t
ORIGIN      
        1 caaatgaacg cgtttctttt gattcataac taatgtaatg ttaagtttaa attgtttaga
       61 atgattttaa aagaatattc aaggaggttt catcaatgga aaaaatcaaa gttgtcattg
      121 taggtgcatc tcatggaggg catcaatcga tcttggaact attgacacga tacggtgaaa
      181 atgtagatat cacgctattt gaagcaggag actatatttc cttcatgtca tgtggtatgg
      241 agctgtattt agaagacaag gtaacagatg taaatgatgt acgtaatttc agaccagaaa
      301 actttccgca atccaatgtt catattttaa ataatcacga agtaaaaacg atcgatgccg
      361 ataaaaaaac agtaacggtt actagcgcat cagataacga aacaaaagaa tatccttatg
      421 acaaattgat tttgagttct ggtgtcaaac caaacaatct gccagtacca ggagcagatc
      481 tagaaaatgt ctacttgatg cgtggataca attgggcaac caaaatcaaa gaaaaattaa
      541 atgatccggc tattaaaaaa atcgctgtcg taggtgcggg ttacattggg atcgaagcag
      601 cagaagcaag ccgaaaagct gggaaagaag tcgtattgct tgatgtgatc gatagacctt
      661 taggcactta tttagatgct gagatgacag atattttaga acaacaccta aatgaaaacg
      721 gtattgaagt tttgacaaat gcaaaaatcg aagcttttac tggtaacgga aaagttgagg
      781 caatcaaaac aagtgaaaaa gaaatcccag cagatctagt cattcaagct gccggtgtga
      841 aggcaaatac agaatggtta aaagggatcg tcgacttaga tgaacgtggc tggatccaaa
      901 caaatgaata cttgcaaacg aatcttccag atgtgtatgc agtaggagat gctacacttg
      961 cttattctat cccagcacgc aaaaaaatgc cgatcgcttt agcgactgtt gcacgtagag
     1021 aagcacgtta tgtagtaaaa catctttttg aagaagtacc aaacaaaccg ttcggcggag
     1081 tcgtaggttc ctctgcatta agtgtctttg actatcattt tgcagcaagc ggattgaata
     1141 gctttacagc agcaaaagca ggagtagatg tacgagtgtc ttattatgaa gatacgttac
     1201 gaccaaaata tgtaccagaa gaacaaggaa atccaaaagt gtccatccaa ttattctcgg
     1261 atccaatgac ccatcaattg ctaggaggag cagtattatc tacctatgat gttacaggtc
     1321 aaggaaatgt attggcacta gcgatccaaa acaaactgac tttagaagaa ctagcagaag
     1381 ctgacttctt cttccagcca ggctttgacc gacaatggag catgttgaat ctagccgctc
     1441 aacaagcgtt aggagaagaa ccatttgtag aataagaaaa cgaaatattt gaaaagaggt
     1501 tgtgaaaaag ctgccttgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
     1561 tttttaactt ggctggactt attaccgcag atgcaagctt ttgaacaccg tttattttca
     1621 aaaaagggac tgtgacacga tttgtgtacc gacccccaaa agttagacca aaaaatctaa
     1681 cttttggagg tcggtatttt ttatggttaa atatactttt gaacttaaat taaagatcgt
     1741 tcatgattat ttggatggca aaggcgattg gaccgtaaaa atccagatca agagattgaa
     1801 gcggaaatgc ttaaaattcg ggagaagcac aaggattatg gctgtttacg gatgaccaat
     1861 gaactaagaa accgcggttt ctctatcaat aaaaagaaag ttcagcgctt gatcaagaag
     1921 ctaggaataa aagtaacggc atacacgcgt aaatcacgtc gctacaattc ttatcgagga
     1981 aaagt
//
LOCUS       DAFTHM010000192         1969 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFTHM010000192 DAFTHM010000000
VERSION     DAFTHM010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.197"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            114..404
                     /locus_tag="L7C88_002808"
     CDS             114..404
                     /locus_tag="L7C88_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559580.1"
                     /translation="MLDMKIEDYRITSDSRNIVLSKVRRDEEGNIRYTEAKEESRADI
                     GYFQTVSSCLKAIQRDYVLSEERTIKSIIEYKKALENITRQFEQACEIEEEK"
     gene            404..721
                     /locus_tag="L7C88_002809"
     CDS             404..721
                     /locus_tag="L7C88_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBP9559581.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGSGVR
                     TSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     DRE"
     gene            718..891
                     /locus_tag="L7C88_002810"
     CDS             718..891
                     /locus_tag="L7C88_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559582.1"
                     /translation="MMMPKEIYSDALRGARNQLKMAKRTYEIRPTIENERRVKAIRRR
                     CSIYGELQKEDSK"
     gene            888..1304
                     /locus_tag="L7C88_002811"
     CDS             888..1304
                     /locus_tag="L7C88_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559583.1"
                     /translation="MIPRFRAWNKKTQSFIDYGDLVLDLRSGKIYAGDIGLVESTIDV
                     TDQIELMQSTGLKDKNGIEIFEWDIVSVSVRNGFDYLDNKVCVVKNSIGHSGLVCATV
                     DEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            1301..1858
                     /locus_tag="L7C88_002812"
     CDS             1301..1858
                     /locus_tag="L7C88_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HBP9559584.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
BASE COUNT          747 a          287 c          461 g          474 t
ORIGIN      
        1 gctgaacagt tatctgaaat tactggatta agcaaaaaca ttatctggga tagagctagg
       61 agcttatgga ttgattcaaa aggacgacag tttaggtatg tggaggagaa aaaatgctag
      121 acatgaaaat cgaagattat cgaattacca gtgattctag aaacattgtc ctatcgaagg
      181 taagacgaga tgaggaagga aatatccgct acaccgaagc aaaagaagaa tcacgagcag
      241 atatcggata ctttcaaact gtctcatcgt gtttaaaggc aatacaacgc gattacgtgt
      301 taagtgaaga aagaacgata aaaagtatta tcgagtacaa aaaagcgtta gaaaacatca
      361 ctagacagtt tgaacaggca tgtgagattg aggaggagaa ataatggatc tcattacaca
      421 atacagtgac atcatcctca agaaaatcat gatgaagatt cagaaagaca aaaaatcaaa
      481 agaacgagcg gaattagtta agttagaaat ggctgaaaca ggatcaggag ttcgaacatc
      541 gaggcattgg aaagcagcag caaacattga attctattac aacgaaattc aaaaagggtt
      601 cgatcagatg cgtgagctgg atcggcaaac aaattggagc aagaaacttc atcaagatcg
      661 tttcaaattt gtagagaaat ataaagagat attagacgaa tacatggagg acagagaatg
      721 atgatgccaa aagaaatcta ttcagatgca ttaagaggtg ctagaaatca attgaaaatg
      781 gcaaaaagaa catacgaaat tcggcccaca atcgaaaatg aacgcagagt aaaagcaatt
      841 cgccgtagat gttcaattta cggcgagtta cagaaggagg acagcaaatg ataccgagat
      901 ttcgagcgtg gaataagaaa actcagtcat ttattgatta tggtgatttg gttttagatt
      961 tgagaagcgg aaaaatttac gctggggaca ttgggttagt ggaaagcacc attgatgtga
     1021 ctgaccaaat tgaactcatg caatcaacag ggctgaaaga taagaatggc attgagattt
     1081 tcgagtggga tattgtatca gtcagcgtgc gaaatggatt cgattattta gataataaag
     1141 tttgtgttgt caaaaattca ataggacatt cgggattagt gtgtgccact gttgatgaag
     1201 atttagagta tcaaattttt aacacagagc tgtttgaaga atacacgtac gaagtcaccg
     1261 gaaatatata cgagaatagc gagttattgg aggaacagcg atgaataaac aggaagcaat
     1321 caaaaagtta gaaagtatta aagcgatagg aaatgatgca atagctgctt gctataacga
     1381 gagtataaat tcaggtatta cgttaatgaa aaaaatagac gaaccgcaga aaccagttat
     1441 tccacaactc gtggccggtt ggcttgagaa atctacggac ccttttacaa aagctgaaaa
     1501 aatagcgtat ttaatcaaat ctaaagatgg tgattcatat tatttctgtg attggtttgt
     1561 acgagatggc atagtgacgc aagagcaagg agaagaatta ctcgcttggg caacaagaca
     1621 atcatatgaa acactattga gcctatacaa cggctacgag gttgagaaag agccgttatg
     1681 ggcaataaag aatgccgatg gaaactatct tactaaatgt gctttatggg gaaaagatgg
     1741 agtaaattat agttttgaat gcaatccatc tcatcgattg cttttcactg ataaagcaac
     1801 agcggatgct gcagcattgt tggtgaatgg aacagtggaa gaggtggtag aaagatgaaa
     1861 ctaaaagacg gattttacgc tagcagtcac ggtatcggcg gtttaatgct agatatgccg
     1921 acaaagaacc ctaaaacacg caagaaatca aaattcaaag tcggtgaca
//
LOCUS       DAFTHM010000193         1939 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFTHM010000193 DAFTHM010000000
VERSION     DAFTHM010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.198"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            137..>1939
                     /gene="glmS"
                     /locus_tag="L7C88_002813"
     CDS             137..>1939
                     /gene="glmS"
                     /locus_tag="L7C88_002813"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBP9559585.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
BASE COUNT          623 a          378 c          409 g          529 t
ORIGIN      
        1 aaagattcgg cggatggccc tagggactgc actctacaga aaatccacaa aaaatgtctg
       61 caaagataaa acaaaaggat tttcctgcag ctggaagcat tcatacgaat tcattataga
      121 aagtaggatg ttttttatgt gcggaattgt tggaatgatt ggattaaaaa atgtaacacc
      181 aggattgatt gacggtctag aaaaattaga ataccgtggt tatgattcag ctggtatctt
      241 tgtctcagat ggcacaactg attatctggt caaagcacaa ggcagaattc aaaatttgaa
      301 aaacaaaata aatattgata ctacaggaaa tataggtatt ggtcatacac gatgggcaac
      361 tcacgggcaa ccttctgaag aaaacgccca tccacatact tcccaaagtg gacgcttcgt
      421 gctcgttcac aacggcgtaa tcgaaaactt tgaagaactt aaaattgctt atttagcaaa
      481 tgaccacttt attggtgaga ccgatactga gattatcgct catctaattg aaactttcgc
      541 gaaggatact acaacgcaag aggcgttttt aaaagctttg cgggtcatca aaggttctta
      601 cgctttcgct ttgattgatc ggacagcacc tgatgttatt tacgtcgcta aaaataaaag
      661 tccactatta atcggactcg gcgatggatt caatgtgatt gccagcgatg caatggctat
      721 gcttgctcat acgaaggaat tcgttgagat tgaagatgaa gagatggtta ccgtcacatc
      781 agaaaaagtt attattcaaa attttgcagg tgacatcgta gaacgttctt cattcgaagc
      841 acaagtagat gcttcagata tcgagaaagg tacctatcct ttttatatgc tgaaagaaat
      901 cgacgaacag cctattatca tgcgtcgtat cgctcaaaaa tacgtaacag aagacaatcg
      961 tgtctctctt gatcaaaagc tggtcgatac attgtctgat agcgatcgaa tctatatcgt
     1021 tgcttgcgga actagttacc atgcggggtt agcaggtaaa cagactttgg aaaaattgac
     1081 acagattcct gttgaggttc atttagccag tgaatttggc tataacacac ctcttctttc
     1141 aaaaaaacca ttctttattt tcttgagtca aagtggcgaa acagcagaca gccgccaagt
     1201 gctggtaaaa atcaaccgtc tcggctaccc ttcacttacg attacaaatg ttgctggttc
     1261 tactctttcg cgggaagcat cctttacact gctattgcat gctggacccg aaatcgcagt
     1321 agcatcaacg aaagcttata ctgcacaaat agctgtacta actttattag ccaaagctat
     1381 cggtgataaa aaagaatttg aaacttctct tgtattcgat atcactcatg aattgagttt
     1441 agttgctaat gcgatggaat cggtcatcgc ccaaaaagat tatttagaag agttggcaga
     1501 agtatatctc agcgatacaa gaaatgcctt ttacattgga cgtggtgctg actacaacgt
     1561 ttctcttgaa gctgctttga aattgaaaga aatcagttat atccaggcag aaggttttgc
     1621 cgctggcgaa ttgaaacatg gaacgattgc tttgatcgaa gaaggaacac cagtgatcgg
     1681 aatcatcagt gaagaagtga ctggtgcgca tactcgagga aacctgaaag aagtcgaaag
     1741 ccgtggcgct aaaacactag ttattgtctc agagggatta gaaaaggaaa gtgaccagct
     1801 ggtgctacca actgtccacc cttatctaac tactctaacc acagtcgtac cgactcaatt
     1861 acttgcatat tacgcaacgc tattacgggg attcgacgtt gacaaaccac gtaatttagc
     1921 gaaatcagtg acagtagaa
//
LOCUS       DAFTHM010000194         1922 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFTHM010000194 DAFTHM010000000
VERSION     DAFTHM010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1922
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.199"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..680)
                     /locus_tag="L7C88_002814"
     CDS             complement(<1..680)
                     /locus_tag="L7C88_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559586.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELE"
     gene            complement(704..859)
                     /locus_tag="L7C88_002815"
     CDS             complement(704..859)
                     /locus_tag="L7C88_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559587.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFILKKN"
     gene            complement(1318..1575)
                     /locus_tag="L7C88_002816"
     CDS             complement(1318..1575)
                     /locus_tag="L7C88_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBP9559588.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(1568..1837)
                     /locus_tag="L7C88_002817"
     CDS             complement(1568..1837)
                     /locus_tag="L7C88_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBP9559589.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
BASE COUNT          627 a          329 c          215 g          751 t
ORIGIN      
        1 ctctctagct cctttgacaa agtgatttga gatttatttg gttccgttgg agtcaattct
       61 atagattctt cataaaaatc tctatacata aagctatcat taattttata aaaaaaatta
      121 aatgttttta gcactgccat ataacattca aaacattctt ctatagttgg tttacttcct
      181 tgaggagaat gaaccaattt attacgtttt tctatgaaat ttttaatttc ctttcttatt
      241 tctttcggaa actcaatatt aaagtaccct ttaaacatgc tccctaataa tttgtctaca
      301 gggggagatt gtaaattctc aaatattaga gttaaatcag gtttctcttg ttgataaaat
      361 tcctttaccc ctatttcaca ggctgtaatt atcgaaataa acctatctct agtatttgat
      421 atatttttac ttcttttaag gagtataaga gaaaagggga tactttcgtg tccatgcatg
      481 taattaacta attgttgagc ttcagaagtt atatctctaa ttatatagtt aacggaatta
      541 ggaagtgtct ttaactctaa tgaaatttct atccaattac tatcttctaa tctgtatatg
      601 ctcgaagtat aatttgattc gtcagcaagc atcgctacat cccaaacact gatcataaaa
      661 tcttttaaac gttcaatcat ttcagcaata ttgctaaaat cagctaattt ttctttagaa
      721 taaaaaaaac atttatatca gaatcaataa attctatttt ttttattact atatcgtcat
      781 cattatcttg accatttatg tttattgttc cctgagtggg gagtacttct ttcaaattca
      841 agttaaattt atattccatt acttctcctc caatatataa aaattactta actgtatcca
      901 aatttaatat gtaaataaat cattaatttt tagctaaatt ctatgagaag tttatttttg
      961 ttgtttttgc taattaacta aaactagtac aaaaaattta aaatagatta ttaaacctat
     1021 tgcttattct attcagtcat atatataagc gtcatccttt agtaactaac atcccacact
     1081 acaatagtat tataacatat ctattcaact tcaaattgtt gaaatttaag ccatttatat
     1141 ttacttttcc tcaactttag aaatgatttt actaacctta tatccgtaat acgcgtaaca
     1201 aacacattca ttaataacaa tcaacactaa gctatattag ctttttaaat gactagggta
     1261 aataaaataa ggatcaaaaa cttttaagtt tctgaccctt tccttacttc cgattggtta
     1321 atagtgatct tttgcagaat aaataaatat cgtttcattt tcaactctat atatcagtct
     1381 atgttcatct gtaattcttc tggaccattt tccagataaa tcatgcttta atggctcagg
     1441 ttttcctaat ccagcaaagg gggaacgatc gatatctttt attaacttgt taatcttttt
     1501 tatattgctt ttgtttcctt gctcatgcca ataaagataa tcatcccaag catcatcaga
     1561 ccaagcctta atcatcagat tcaacctcga ttaagtcatg tgttttaaat gcacctttgg
     1621 agaattgttc atctcctcga cgaatttttt ccatgacgta attattagaa agtgttctca
     1681 acgtttcttg catagaatca taatctcttt ttgataatac aacaactgta tcttctacat
     1741 ctttacttgt tacaataagt gtttcagcat cctcattaac ttgtttcata taactacgta
     1801 aattttggcg gaaatttgaa taagctactg cttccattcc tttcacccct tatttatttc
     1861 tataaaacaa ttgtacatta tattgtacaa ttaagcaaat gattaatatt ctaacttctt
     1921 at
//
LOCUS       DAFTHM010000195         1915 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFTHM010000195 DAFTHM010000000
VERSION     DAFTHM010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.200"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..153
                     /locus_tag="L7C88_002818"
     CDS             <1..153
                     /locus_tag="L7C88_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBP9559590.1"
                     /translation="NKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFSFSVSTEIKV
                     LMGITA"
     gene            159..575
                     /locus_tag="L7C88_002819"
     CDS             159..575
                     /locus_tag="L7C88_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559591.1"
                     /translation="MEFREGAFDFQTSQQNRKFIPEDFQNLQLENMRLEDLFRLADDD
                     KYRFEVLKIKKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNR
                     NSTDVVMITDIYVEDEVIIKYMKPVIKLVNKNKGNG"
     gene            681..944
                     /locus_tag="L7C88_002820"
     CDS             681..944
                     /locus_tag="L7C88_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBP9559592.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            944..1216
                     /locus_tag="L7C88_002821"
     CDS             944..1216
                     /locus_tag="L7C88_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBP9559593.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            1293..1622
                     /locus_tag="L7C88_002822"
     CDS             1293..1622
                     /locus_tag="L7C88_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBP9559594.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1612..1898
                     /locus_tag="L7C88_002823"
                     /pseudo
     CDS             1612..1898
                     /locus_tag="L7C88_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
BASE COUNT          727 a          235 c          381 g          572 t
ORIGIN      
        1 aataaatttt atcaaagtct ccgtacagcc tcttccacga ttaagggcat ggagaccatt
       61 cgaggaatat ataaaaagaa ccgaagaaat ggaacgctct tcagcttttc ggtgtctact
      121 gaaatcaagg tattaatggg aataacagcc taagatattt ggagttcaga gagggcgcgt
      181 ttgattttca aacttcgcaa cagaaccgaa aatttatacc ggaagatttt caaaacttac
      241 agttagaaaa catgcgttta gaagatttat ttagattagc agatgatgat aagtatagat
      301 ttgaagtttt gaaaattaaa aagaatgaac tattgaataa gttatatcct gagaatgcga
      361 taaaagcaca ttttggtgat gctaatcata tgtatagttg gttcattcct aaaagattta
      421 gagggaaaat caatgctgga gatcaagtga aagtactcaa tcgaaatagt acagatgtcg
      481 taatgataac agatatctac gtagaagatg aagttataat caaatatatg aagcctgtga
      541 taaaacttgt taataaaaat aaaggaaacg gataacactt tacaatgctg ttttggtact
      601 ccaatttaaa caaaacaatc gaatttacgt acttaattaa gtacgttaga atggagatat
      661 aaattagagg gggagtagat atggcaaaaa cagtcttaaa tcctagctca gcacggaaaa
      721 atttttataa gttgttgaaa gatgtaaatg agaatcatac ggaaattgaa atcattagtg
      781 agcgcagtga aaataatgcg gtgcttattg gtttggatga ttggaaagca atcaaagaaa
      841 cgctattact tgagcaaata ggcactttgg gtgttgttcg taagcgagaa aaagatgata
      901 gtggatttac taatgttgat gaaattgatt gggataactt ataatgaata actattctgt
      961 gatgattaaa aactcggcta aagctgattt aaagaaaatc aaacagtcta atttgaaacc
     1021 tcaatttgag aaggttattc agactttaaa ggaagatccc tatctcccta cccaatcatt
     1081 tgagaagtta aaacctacac atgaaggtag gtattctaga agattgaata gacaacaccg
     1141 ggttgtttat aaggtagatg aagatgaaca cgtggttgaa atttattcag caaggacgca
     1201 ttacgagtca cagtaattac ttgtaaatac attatctcgt ggtataatgt atttactaag
     1261 taattacata ctgttagaaa tgagggattt aaatgattac aaaaacaaga aaacaaggca
     1321 attcaatcat gttgacagta cctaaagatt ttaatgttcc taatggagtc gaagttgaag
     1381 caaagttggt agagaatggt attctttatg aatttgttga accacaaaaa gaattttatg
     1441 attttagcga agatattttg tctgatataa ttgcagaagg ctacgataaa gatgagattc
     1501 ttgtagaatt taagaataga aaaaacaaaa tgcattcttc ctttagagat attgctgaag
     1561 atacacttac taattctaaa gtaatgacta aagaggagtt ggcaacagaa attggcttat
     1621 gaaatcgttc cttcaaaaca tgtcattaag tatttaaaaa gctaaaagag aagccattga
     1681 aagaaaaatt tttgaattta atttatgatg aaattgcgat tgatccatat aagggtgaac
     1741 aaaaaactgg ggatttatca ggtatttggt ctagtgggtt caaatatgcg ggcacaacat
     1801 atagagtagc ttacgagatt atagaaaaca aggttattcc agtattgtta tgtggaacgc
     1861 atgaaaactt ttatgaacag ttgaaaaaat taatctagtg atttgttgtc gttct
//
LOCUS       DAFTHM010000196         1913 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFTHM010000196 DAFTHM010000000
VERSION     DAFTHM010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1913
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.201"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..778)
                     /locus_tag="L7C88_002824"
     CDS             complement(<1..778)
                     /locus_tag="L7C88_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBP9559595.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEM"
     gene            complement(824..1603)
                     /locus_tag="L7C88_002825"
     CDS             complement(824..1603)
                     /locus_tag="L7C88_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559596.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
BASE COUNT          537 a          384 c          319 g          673 t
ORIGIN      
        1 tcatttcatc aaagttcatg tctgttttca tattcgactc tagagcattc aaaacggatt
       61 gatagttgct gacaccgttt agactcaata cttttttcgc tacgccttct acgatctttc
      121 tttggcgccc ttgtctaccg taatcaccat ttgggtcttc ataacgcata cgagaataag
      181 ataatgcctg atccccgttc aatgtaattt taccgattgg aaagtcatag ccatcttgtg
      241 agaaagtgag gtcattattg acttcgatac caccaactgc atcaacgagt tcctttagcc
      301 ctttcatatt gatagagaca tagtgatcga ttgggatgtc tacatatttt tgtacggtat
      361 ccatcgccat ggcagctccg ccgaatgcgt aagcgtggtt gatcttgtct tttgtgtcac
      421 gacctacgat gtcgacatac gtatcacgag gaatgctgac gatcgttgtc tgtttgtctt
      481 caggactgac tgtggcaacc atcatcgtat ctgatcttcc ttgatcgacc cgacctaaat
      541 ctccagtatc aatccccatc aatagaacag agaaagattc ttgtttgtcc agatcaactg
      601 gtttcgttcg ttctccttgg gttcgttcca ctgattcgta agttttctca atagaatgtg
      661 agagatccag atataatttt gctcctactc ctacaattgc taatactaat acgataagaa
      721 ctgctaaaat aatcagaaat atttttttcc ctcttgattt tcttcttcgt cttgccatag
      781 tttcctccgt ttgctaacct tgcttgaatc aacgttttaa ctgtcaatag cttatattgc
      841 tatagcccat ttgctcagca acagtttgtg cttttgttgc gtatgctgcg cttatttttt
      901 cattccggat ctgctctatt tgactgagca ccgtcaaata ttgatcgtaa gtagcggtgg
      961 cagtcacttg accatccttt aacatcgtat cgaataactg atctagttgc gtgacttgcg
     1021 cgatctgaat atcagcgaat cctagatatt gcataacaac cgttttccaa ggactatctt
     1081 taaaaaagct catattttca cgtacacgag cgacatctgc acttgtcacc ttttctttga
     1141 tgatgacatc gtctacagct tgctgccagt ttgatacatt tttagtaaat aaatcgttga
     1201 cagctgtctg gatcttcagt tttgattctg cactatctaa ctgtgtcacg attgctttct
     1261 tctcatcttg gattgcaaca gcttctttag gcaattctga ttctttgatg tcgtaatcat
     1321 ctgctgaaag tttgacagag gatagcttat ttgacaaact tgtgattgtt tcttctgtta
     1381 tttcagggtt tagaaaaatt ttttcttttg tactatacag cttgtctact tcttttgata
     1441 aagaagtcaa ggtgtctttt tgattggtga tggcagattc tgcataattg atccgttgct
     1501 gatgttgccg ctgattattg atatggtatc caaacaaaca gatcgcaata gcacctgcac
     1561 ctaccgccac agcagtcaat gacttgacga atggcttttc catagattca ctcctaagta
     1621 ttgatgatag ataaattaag atataattca cttacataaa aatgacagct ttttatttaa
     1681 aaaaacataa ttaaactaat atattcacag aaatatttgt aaacaagttt tccctatata
     1741 atcataccac aaactgtttt cttgactagg gcaatttacg atttaaaagt aaataaaaca
     1801 ttaataagat aaaaattaat cgatttcatt tttatttcca taattttcat aggtgttttt
     1861 aaaagttaca caaaaaatag aataacaaaa aaattaacat tgaattaata ata
//
LOCUS       DAFTHM010000197         1892 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFTHM010000197 DAFTHM010000000
VERSION     DAFTHM010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.202"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            16..525
                     /locus_tag="L7C88_002826"
     CDS             16..525
                     /locus_tag="L7C88_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBP9559597.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            618..1780
                     /locus_tag="L7C88_002827"
     CDS             join(618..894,894..1780)
                     /locus_tag="L7C88_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBP9559598.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
BASE COUNT          669 a          343 c          380 g          500 t
ORIGIN      
        1 tagggctata ctatattggt acaaggaata gaaagaggtg tttatgtggt tgataaaatt
       61 cagtttaatc aagttataga agaattcatc aaagtaaata atttaatgac ccatattcaa
      121 aaacgaccaa tcagaataac taatgatcta aaactcagta cgagtatgat tcatttgatt
      181 gatgtgattg gaaattatcc tgaaactagt attacggaat tagctgatcg attaggcgtt
      241 accaaaggag ctgtatccca acagattccc actttagaga aaatgaatct tataagcatt
      301 tctcaaaaaa aaggaaataa gaaaactaaa cttgtatcgt taacaaaata tggtcgaaag
      361 gtgtacgaat cacataatta tttacatgaa gagctttata gctcaataaa tgaagcgtta
      421 gaatcattct caccagacca aatttcaacc attaaacaga ttctagaaaa agtatcttat
      481 acaatcaatg aatatcaagt aagtctgaca agaaaggaag attgacatga aaaaaatgat
      541 ttttgaatcg gctacactag actagacaga aaaaataagg tgtgtaaaat aaatgaaaac
      601 acactggagg aatttttatg tcaagacgtc aacgtagaac ctattcaaaa gaattcaaac
      661 aacaagtcgt cgatctttat ctcgcaggaa agccccgagc tgaaatcatt cgagattatg
      721 agctgactac ctcggccttt gataagtggg tcaagcaagc gcaaactact ggctcgtttc
      781 aggaaaaaga taacttgatc cctgaacaag tagaactaat tgcattacga aagaaaaata
      841 aacagcttga aatggagaat gacattttaa agcaagcggc gctgatattg ggacgaaaag
      901 acaagtaatt gataccaata agcacaaata ctcaatatca gcgatgtgta aagtgttaaa
      961 catctcttgc caaacctatt attatcaagc caaaccagtt gaagatgaat cagaactgga
     1021 agaactcgtt caagaagaat ttattcgcaa tcgaaaagct tatggtacca ggaagctgaa
     1081 gcagtgcttg gccaatctag gtcttcaagt gagtcaacgc agaatcggcc gtatgatgaa
     1141 acagcgtggc ttgcgttcaa catacacatt ggctcatttc aaattccatt cttctacttg
     1201 taacgaagcc aagaccgcca atattctaga cggaaccttc ctacaggaaa agtcattaga
     1261 agcgattgta accgacctta cctatgttcg tgttgggaag aaatggcagt atatctgcct
     1321 gattcttgat ttgtttaatc gagaaatcat cggctattca tgcggggaga agaaagatgc
     1381 gacgttagtc aaggaagctt ttgcaaagat tccgtactcg ttgaataatg tacaactttt
     1441 tcacacggat cgtggaaaag aattcgataa ccagacgatt gacgaaattt tatgggcctt
     1501 taatatcacg cgttccttaa gcaaaaaagg ctgcccctat gataacgccg ttgcagaatc
     1561 cacctataaa tctgtcaaag tagaattcgt tcatcaatac cgctttgaga cattggctaa
     1621 tttgcgatta gagctatttg attacgtcca ttggtggaat accatccggc tgcacggcac
     1681 gttaggctat gagacaccga tcagttttcg acagcagaga ttggcgcagc gaatccttga
     1741 taatgagctc ggatgtgata ccggtggcga ggcaccttaa ttatttgaat gagcttctgc
     1801 cttagagaat cagattcgag gaggctcgtt gtcaagggca gtcggaacac cagcagcaag
     1861 cttacgcaat accttataat ttttgtcaaa aa
//
LOCUS       DAFTHM010000198         1830 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFTHM010000198 DAFTHM010000000
VERSION     DAFTHM010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.203"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..671
                     /locus_tag="L7C88_002828"
     CDS             <1..671
                     /locus_tag="L7C88_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBP9559599.1"
                     /translation="QYEQQLKRKELVYLKKYTDSLEKDQEKFARFRHDYKNLLLSLKE
                     IANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKNEYLKSLLIAKLYQANNNKI
                     CCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQDRELSLAIYRDDKQIEISI
                     SNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKKNPNMFVNYQNDPYQFTTQV
                     ILLF"
     gene            686..1438
                     /locus_tag="L7C88_002829"
     CDS             686..1438
                     /locus_tag="L7C88_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9559600.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
BASE COUNT          707 a          216 c          308 g          599 t
ORIGIN      
        1 aacaatatga acagcaattg aaaagaaaag aattggttta tctaaaaaaa tatactgatt
       61 cactggaaaa agatcaagaa aaatttgcca gatttagaca tgactataaa aatttattgc
      121 tgagtttaaa agaaatcgct aatcaaaacc atgattcgat attggaaaaa gaaataaaag
      181 aattagagat ctattctaat tcttatctaa ccaataagtt tgaatatcgt tatttaaaaa
      241 atataaaaaa tgaatatttg aaaagtttgt tgatagcgaa gctataccaa gcaaataaca
      301 ataagatttg ttgtaaattc gaatgtccaa gtactattat tgaagttcct gttccaatat
      361 ttgactgtat tagggtgctt ggaattattc tcgataatgc aattgaagca tctatagaga
      421 gtcaagatag agaactgtct ctagctattt accgagatga taaacagata gaaatttcga
      481 tatcgaatag ttgtagagag atactactct ctatagatac tctaatgaaa aaaggaataa
      541 caacaaaaaa gggacatcaa gggttaggtt tatctagtat agaggaaatc aataaaaaga
      601 atcccaatat gtttgtgaac tatcaaaacg atccgtatca atttactact caagttattt
      661 tgttgttttg agggaaggag gatttatgag ttatccaata atattatgtg aagatcaaat
      721 tatacaatta aatcagttag aacgaattat tgataatttc attctttttc acgataaagt
      781 atttaagata gtattgaaaa cacaaagtcc gttagaagtt aaaaaatacc tcaaacaatt
      841 ccgaccaaag caaggaatat atttcttaga tattgattta aatcatgaag ttaacggtat
      901 agaattagca gaagtaatca gaaaatatga tgttcaagca aaaatcattt ttacaactac
      961 tcatgatgag atgttacccg taacaataaa aagaagagtt gaaacgttag gatttgtaac
     1021 aaaagatcaa acactagatg agtatcgaaa cgagattgtt gagttattgt tattagcgca
     1081 agaaaggata gatgcaacaa aacaggttac gaatcaagca tttgtttttt ccataggttc
     1141 tcaaacattt acttttgata taaatgacat ttattttgta gaagcttcaa aattaccaca
     1201 tagattatca ttgtgtacta aagatgggca gtacgaattt tatggaagaa ttagtgagct
     1261 tgaaaagaaa tatcctatgt taacaagaat tagtcgagcg tgtttagtaa atatctttaa
     1321 cgttaaagaa atagatttta aaaaacgttc actatatttt gattcagagt tggccagaaa
     1381 ctttacttta gggaaagcac aaaaaattaa ggagaagttg aaagaaagca ctgtttagtg
     1441 gttttttctt tagggagatt gcatttttct aataaaatag attccttcac tagtgcaaat
     1501 ttttctgaat cctattaaag ttgtaccaat ttttatagct gttattagtt acgtgcataa
     1561 cagcaatatt agttactgga ggaatatttc tatggtctgg aaccaaaaaa gggccaaatg
     1621 aatagttctt ttcttgtttt tattaagtac cataaagggg aattaaaatt aaatgtatgg
     1681 tggaagatgc gaaagatttg gcaaattcta ctaattttta gaaagtgttt ttcatttttt
     1741 agttaaaaaa tttgtcctgt caagtgcaat cctatgattg tacttgatag gatttgagat
     1801 aattactttc ctgtttttat aaatttaact
//
LOCUS       DAFTHM010000199         1796 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.205, whole genome shotgun sequence.
ACCESSION   DAFTHM010000199 DAFTHM010000000
VERSION     DAFTHM010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.205"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            29..1381
                     /gene="brnQ"
                     /locus_tag="L7C88_002830"
     CDS             29..1381
                     /gene="brnQ"
                     /locus_tag="L7C88_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBP9559601.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT          503 a          309 c          353 g          631 t
ORIGIN      
        1 ttttaaaaaa accgtaaagg agttatgtat gacaaaaaaa ttatcattta aagactatct
       61 ttttataggc tccatgcttt tcggtctatt ttttggtgct ggaaatctta tctttcccgt
      121 tcatttgggt caagaagcag gcgctgctac cttttgggcg aatctaggtt tcttggttac
      181 cggtatcggt cttcccttct taggggtgat tgccattggt gtatcgaaaa gctcaggtgt
      241 atatgaatta gcaaaacgga taaatcaaac atatgcgatg gtttttacca tcttgcttta
      301 cttagttatc ggaccgtttt ttgctttacc tcgccttgca accacatctt tcgagattgg
      361 tttagcacca tttatcgatc ctagcagaca gacgctatat ctagcaattt tcagtattgt
      421 attttttgtg ctggcttggt ggttttcaag aaaaccgaca aagatattag attatgttgg
      481 aaagttcctg aatcctgcat ttttggtttt attaggtgct ttgcttctcc ttgctttttt
      541 gaatccacta ggttctgtaa atcaagcgcc tattcagcca aattatcaag agcatgcttt
      601 tttcacaggg tttactcaag gatataacac attagatgcg cttgctgctt tagcatttgg
      661 gatcatcatt gtcacaacaa tccaaaacat gggtgtaaca aaacctgctg aaatcgctaa
      721 agacacgatc aaatctggtg cgatcagcat tatattgatg ggaatcattt atactttgct
      781 cgcttattta ggtgctatga gcttaggtag ctttgctcta agtgaaaatg gcgggatcac
      841 gctggctcag attgctgatc attatttagg tacttatggc agtatcttat tagcatttat
      901 cgttatatta gcttgcttga agaccggtat tggtttgatt acagcttttg cagaaacatt
      961 cacagatttg tttccgcaaa gaaattacgc attctttgtt gcacttgcta gtatccttcc
     1021 ttgtttagcg gcaaacgtag gcttgacgaa tatcattcaa ttttcgttgc ctgttttgat
     1081 gttcatctat ccattagcaa tgacactgat tttactagtg ttagttggtc ctttgtttaa
     1141 gcagcgtacg gctgtttatc gaatgactac ttattttaca ttgattgctt cgatttttga
     1201 tgggttgaac gcttgcccag aaactatcaa acaaacacct attgttcaaa atcttttata
     1261 tgttgcggaa agctacttgc cgtttttcaa attggggatg gggtggatcg taccagcagt
     1321 tatcggtttt gttatcggac tgatttggag tttcgctaag aaagaagaag tagcagattg
     1381 ataaaagagg ttgtgaaaga gacgttcagc cttgagcaat aaaaagtaat tttgaaaaat
     1441 ggcttctcac atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg
     1501 tttattgaga ggtcgtgaaa aagccgctta gtttcaagta ttaagaaata ttttgtgaaa
     1561 atggcttctc acatttttgc ataaatttga cttaataccg agaaactggc ttttgaacac
     1621 cgtttattga gcgtctataa actgacctga gtattagaga aacaaaacgg caaagtagct
     1681 ccatatactt tgccgttttg ttttgaacta ataccgaaga gaagctgatc aaacaacatt
     1741 tcttttataa tatagatttt agacatatat atgatataaa aatagttttc gcaaaa
//
LOCUS       DAFTHM010000200         1738 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.206, whole genome shotgun sequence.
ACCESSION   DAFTHM010000200 DAFTHM010000000
VERSION     DAFTHM010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.206"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            1..1234
                     /gene="aph(2'')-I"
                     /locus_tag="L7C88_002831"
                     /pseudo
     CDS             1..1234
                     /gene="aph(2'')-I"
                     /locus_tag="L7C88_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
     gene            1218..1610
                     /locus_tag="L7C88_002832"
     CDS             1218..1610
                     /locus_tag="L7C88_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9559602.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
BASE COUNT          715 a          133 c          297 g          593 t
ORIGIN      
        1 atcattaaaa aaacattata cagagccttg ggaagatgaa gtttttagag taattattga
       61 atataacaat gttcctattg gatatggaca aatatataaa atgtatgatg agttatatac
      121 tgattatcat tatccaaaaa ctgatgagat agtctatggt atggatcaat ttataggaga
      181 gccaaattat tggagtaaag gaattggtac aagatatatt aaattgattt ttgaattttt
      241 gaaaaaagaa agaaatgcta atgcagttat tttagaccct cataaaaata atccaagagc
      301 aataagggca taccaaaaat ctggttttag aattattgaa gatttgccag aacatgaatt
      361 acacgagggc aaaaaagaag attgttattt aatggaatat agatatgatg ataatgccac
      421 aaatgttaag gcaatgaaat atttaattga gcattacttt gataatttca aagtagatag
      481 tattgaaata atcggtagtg gttatgatag tgtggcatat ttagttaata atgaatacat
      541 ttttaaaaca aaatttagta ctaataagaa aaaaggttat gcaaaagaaa aagcaatata
      601 taatttttta aatacaaatt tagaaactaa tgtaaaaatt cctaatattg aatattcgta
      661 tattagtgat gaattatcta tactaggtta taaagaaatt aaaggaactt ttttaacacc
      721 agaaatttat tctactatgt cagaagaaga acaaaatttg ttaaaacgag atattgccag
      781 ttttttaaga caaatgcacg gtttagatta tacagatatt agtgaatgta ctattgataa
      841 taaacaaaat gtattagaag agtatatatt gttgcgtgaa actatttata atgatttaac
      901 tgatatagaa aaagattata tagaaagttt tatggaaaga ctaaatgcaa caacagtttt
      961 tgagggtaaa aagtgtttat gccataatga ttttagttgt aatcatctat tgttagatgg
     1021 caataataga ttaactggaa taattgattt tggagattct ggaattatag atgaatattg
     1081 tgattttata tacttacttg aagatagtga agaagaaata ggaacaaatt ttggagaaga
     1141 tatattaaga atgtatggaa atatagatat tgagaaagca aaagaatatc aagatatagt
     1201 tgaagaatat tatcctattg aaactattgt ttattgatga taatatggtt tttgatattg
     1261 ataatttaaa aggatttctt aatgatacca gttcatttgg gtttatagct aaagaaaata
     1321 ataaaattat aggatttgca tattgctata cacttttaag acctgatgga aaaacaatgt
     1381 tttatttaca ctcaatagga atgttaccta actatcaaga caaaggttat ggttcaaaat
     1441 tattatcttt tattaaggaa tattctaaag agattggttg ttctgaaatg tttttaataa
     1501 ctgataaagg taatcctaga gcttgccatg tatatgaaaa attaggtggt aaaaatgatt
     1561 ataaagatga aatagtatat gtatatgatt atgaaaaagg tgataaataa atgaatatag
     1621 ttgaaaatga aatatgtata agaactttaa tagatgatga ttttcctttg atgttaaaat
     1681 ggttaactga tgaaagagta ttagaatttt atgatggtag agataaaaaa tatacatt
//
LOCUS       DAFTHM010000201         1672 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.207, whole genome shotgun sequence.
ACCESSION   DAFTHM010000201 DAFTHM010000000
VERSION     DAFTHM010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.207"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(48..1472)
                     /locus_tag="L7C88_002833"
     CDS             complement(48..1472)
                     /locus_tag="L7C88_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBP9559603.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
BASE COUNT          474 a          359 c          260 g          579 t
ORIGIN      
        1 atttaaatcc aagctgttat attctttaat ctatttactt tgtgaaatta ttctgttaac
       61 cacttttcta gaattttcat ctttgaataa aacaacggta tttggttttc atccagccta
      121 ctgtaattga ttctgattcc atttatatct tgcccaaaaa gtagacttgg tgcaattcca
      181 agacccatat ctactacttt ttctgctagt tcggggtcta gttttttccc atcccaagta
      241 atccaggcat agtaaccacc taaaattgaa tgaagcttga aaaacgattg tgaatctccc
      301 caagcgctta tcagtcggct tttttctttc aacttttttc ttacatcttg cattttcaaa
      361 tcaattgctt cattaaatac attagccact gtgatttgtg taaggatatt catcgaaaac
      421 tccatcattt cttgcgcttg agctagttgc gagataaaag tctcaggtcc tatcacccaa
      481 ccgattttcg ttgtttttcc taaaacccta gataacgaac cgacgtataa cacattatcc
      541 ggatcaatcg ttcgtatagg aaggacttct tcttggttta gaaatgaaag atccgtaaat
      601 acatcgtctt caataattgg aagccgatac tgtcgacaca attctactag cttttctcgt
      661 cgtttttgac tcatcacttt tcctgtaggg ttttgaaaat tcgggttgat aagcactgct
      721 ttcaatttat ttttatggat cgattctttc agtttttcta agtcgatccc ttcttcatcc
      781 atcggtatcc caaataaacg cgttcctgaa gctttgaaaa gaggtaatcg gtaaaaaaaa
      841 gaaggtgact ctacagctat cccctctcca gctgaaagaa tcgtttgtaa aatcaaaaag
      901 attgcttgct gaccgccacc agtcacaaga agctggttgg gggaaaatgc caattcaaat
      961 ttactttcca aataccgttt gattttgtta cgtaacggag tatagcctaa aagatccatt
     1021 tctttttctt ccgctaagat ttcttcaaga gaataagaag gaaactcaaa attcggcaaa
     1081 agctcatctg gcatctcgct agcgtataaa tcaagaaacg atgttttttg gatctgcttt
     1141 gcttctctta ttttttgctc ataccagtcc gtctgctcat aacgaggaga gatcatttgc
     1201 cgccaatcga ttcttggaac agcgaatttc ccccattcag tctgattaac aaaccatccg
     1261 ctgccacgtt tgctcgttag taccccaagc tccctaagct cttccaatgc atggacaacg
     1321 gtggaacgat tcacaccaaa aagttgccct agttttcgtt ctgattcaag ttgacttcca
     1381 ggattgatcc ttccgttttc gatttctctc ataatctgtt ccataatttg acgataaatc
     1441 ggtccttgtt ttttctctac tttttcccac ataagcttct cttttctatt gtctattttt
     1501 tcttttgatt ttaccgaatt tacgagaaaa aagaaaaact ttttttgcaa aacataaggg
     1561 actgtgacaa aaatcttatc acagtccctt attctgaata atgatgttca aaagcttgta
     1621 tctgcgataa taattccagc caaacaaaac atataaagaa ctatttttgt tt
//
LOCUS       DAFTHM010000202         1642 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.208, whole genome shotgun sequence.
ACCESSION   DAFTHM010000202 DAFTHM010000000
VERSION     DAFTHM010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.208"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(1..>1642)
                     /locus_tag="L7C88_002834"
     rRNA            complement(1..>1642)
                     /locus_tag="L7C88_002834"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          348 a          507 c          350 g          437 t
ORIGIN      
        1 taagtcctcg atcgattagt atcagtccgc tccatacatc actgtacttc cactcctgac
       61 ctatctacct gatcatctct cagggatctt actttcttaa agaaatggga aatctcatct
      121 tgaggtgggc ttcacactta gatgctttca gcgtttatcc cttccctaca tagctaccca
      181 gcaatgccct tggcagaaca actggtacac cagcggtaag tccatcccgg tcctctcgta
      241 ctaaggacag ctcctctcaa atttccaacg cccgcgacgg atagggaccg aactgtctca
      301 cgacgttctg aacccagctc gcgtgccgct ttaatgggcg aacagcccaa cccttgggac
      361 cgactacagc cccaggatgc gacgagccga catcgaggtg ccaaacctcc ccgtcgatgt
      421 ggactcttgg gggagataag cctgttatcc ccagggtagc ttttatccgt tgagcgatgg
      481 cccttccatg cggaaccacc ggatcactaa gcccgacttt cgtccctgct cgacttgttg
      541 gtctcgcagt caagctccct tctgccttta cactcttcga atgatttcca accattctga
      601 gggaaccttt gggcgcctcc gttacctttt aggaggcgac cgccccagtc aaactgccca
      661 tctgacactg tctcccacca cgattagtgg tgcgggttag agtggccata acgcaggggt
      721 agtatcccac cagcgcctcc atcgaaacta gcgttccgat ttctacggct cctacctatc
      781 ctgtacatgc ggtacagaca ctcaatatca aactacagta aagctccatg gggtctttcc
      841 gtcctgtcgc gggtaacctg catcttcaca ggtactaaaa tttcaccgag tctctcgttg
      901 agacagtgcc caaatcgtta cgcctttcgt gcgggtcgga acttacccga caaggaattt
      961 cgctacctta ggaccgttat agttacggcc gccgtttact ggggcttcaa ttcgtacctt
     1021 cgcttgcgct aagcactcct cttaaccttc cagcaccggg caggcgtcag cccctatact
     1081 tcatcttacg attttgcaga gacctgtgtt tttgataaac agtcgcttgg gcctattcac
     1141 tgcggctgat cgtatgatca gcaccccttc tcccgaagtt acggggtcat tttgccgagt
     1201 tccttaacga gagttctctc gctcacctta ggattctctc ctcgactacc tgtgtcggtt
     1261 tgcggtacgg gccgctgttt tctcactaga agcttttctc ggcagtgtga catcaggaac
     1321 ttcggtacta ttatttccct ccccatcaca gcttgtcctt aagaaaagaa gcatttgact
     1381 cctcttcaga cttactgctt ggacagacat ttccgatcgt ctgcattcct tagcctcctg
     1441 cgtccctcca ttgctcaaac aaaaacaacg ggtacaggaa tatcaacctg ttatccatcg
     1501 cctacgcctg tcggcctcgg cttaggtccc gactaaccct gggcggacga gccttcccca
     1561 ggaaacctta gtcattcggt ggacaggatt ctcacctgtc tttcgctact cataccggca
     1621 ttctcacttc taagcgctcc ag
//
LOCUS       DAFTHM010000203         1609 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.209, whole genome shotgun sequence.
ACCESSION   DAFTHM010000203 DAFTHM010000000
VERSION     DAFTHM010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.209"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            33..1091
                     /locus_tag="L7C88_002835"
     CDS             33..1091
                     /locus_tag="L7C88_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBP9559604.1"
                     /translation="MVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPGLLARQGF
                     IEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQIFYITLSS
                     SRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFSFGTNYAK
                     DFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIWKAALKVI
                     RPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLVSSGIIAF
                     ICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFNKRDVISI
                     VFWYYLGSISYLYLKKEN"
     gene            1093..>1609
                     /locus_tag="L7C88_002836"
     CDS             1093..>1609
                     /locus_tag="L7C88_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559605.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVK"
BASE COUNT          549 a          188 c          260 g          612 t
ORIGIN      
        1 tttcacaaag tgaagaggaa aaaaagaaaa aaatggtgta ttttaataat gttttcatta
       61 tcataatttt tttagctgcg ctaatatcta tctatcaatt tatttttttg atttcttatc
      121 atgtcccaac aggaacgcca ggattacttg caagacaagg ttttattgaa catcggttat
      181 ttggtgtcta tacaagtcca aatgttggag ctatgtttgg atatacttct attattttaa
      241 gtttaattag tgtattaatt tcaaaaataa caaaaacgat tcgtgttttt tatatgatga
      301 attttatcgt acaaatattt tatattacac tttcttcgtc tagaggtgcc caggtagtaa
      361 tttgttcttt tttagtatta tttcttttgt tgtttgccaa ttcaaaattt agaaagagca
      421 ttagagaagt actacctgta aaaatcaaat ggatggtaag catattatta gttctattgg
      481 tatatttttc ttttggtact aattatgcta aggatttttt agcaacaatt cctgtatcga
      541 ttgatagaaa agtagaagtt atagagtcaa atgaatcaga taaaactcca cttccagaaa
      601 aagaagtaat attacagcat tctagtgata actccgaaat ttcagctggt cgttttacga
      661 tttggaaagc tgcgcttaaa gttataagac caactttgtt atttggttat ggagagaccg
      721 atttctatgg gaatagcgat gcaaaatttt tgaaaaaagt agatcttgat actacagatg
      781 tgaatgaact aaaaagagca catggaaaca tgcataatgg atttcttcaa gtacttgtat
      841 caagtggtat aattgctttt atatgtatct atgctttcta tgtgttaaat atctttagtt
      901 tactcaaaac attttttaga agtaaagtga attatgcgtt tcttggtatt gttttaattt
      961 ttatactatc tatttttata gatgaaatgg tggaggctca tgtacttttc aataagcgcg
     1021 atgtcatttc aattgttttc tggtattatt tgggaagcat ttcttacttg tatttaaaaa
     1081 aggagaatta atatgaagac agctttcatt gcttggactc ctttacattt gattaatata
     1141 ttaaatgttt atcaaaattt ttaccgagaa tcaaaaggag atttatttat ttattctgaa
     1201 tttgaaaacg ctagaagata tagtgagcgt ataaaagaat tagggctatt taatgatgtt
     1261 gtttttgtga atcaccggaa aatcggttct tcctttaaac gtaaaattaa cttgttaact
     1321 aaccataatc aatttttctc ggatgattta tccgtttatg atgaaatttt tatacagggg
     1381 gaaaattatt tcacaaaaat acttttctcc aatgtttaca aaaaaaatcc agatgtaaaa
     1441 ctaaattata tagaagatgg tttgggtact tatttgaaga agagtatatt ttcaacaagt
     1501 aaaaacgttc aaagagtttt taaaatatta aataaaaata gcatcttcaa aaaaaaaatt
     1561 gacgattatt ttgtctattg tccggaattg ttactttatg atgtaaaaa
//
LOCUS       DAFTHM010000204         1599 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.210, whole genome shotgun sequence.
ACCESSION   DAFTHM010000204 DAFTHM010000000
VERSION     DAFTHM010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.210"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            770..>1599
                     /locus_tag="L7C88_002837"
     CDS             770..>1599
                     /locus_tag="L7C88_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBP9559606.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT          571 a          220 c          244 g          564 t
ORIGIN      
        1 attttgctcc acttttagat aatttttagg tctatttaac tcatcagaca ttctatgctc
       61 atttttctcc aaatttgttt caactctttc gtacttaatt ttgcgtattt gaaaattctt
      121 cttttagagt acttttatta cgatactagt atgatatata tctatagcaa acagttaaaa
      181 tcttcctaaa ataagcgaat agcattccta aaacctataa aatttttaga tgaagcgaca
      241 agtggacaat taataaacta cttgaacatg aaattatgga tcacctttca aatttagaaa
      301 atggaattct tatacttatt gcgcaacatt tattgattgc aaaattatgt gacaaaaaaa
      361 actagtagaa gaaagaataa tggcttgata ataaagtact acctattaaa ggtagtactt
      421 tatttaattt agtataaatt aacatactac tatattttag gtttcatatt atataaatta
      481 ataatatact accatttgtt ggtagtataa tttaaaggta ataagttatt cttttattac
      541 tatgtttggg ttttatagca aagaaagttt aataagagtt tggacctagc aaacaatatt
      601 aatgaggtca ttaaatctta ttatctttag tgatataacg aaatatctac acagacaaaa
      661 tgatagcgta aaatattttg tgtaaataga tatttagggt agaaaaaaag aaagtccatt
      721 ctgtaaaatt aaagttacca caaccgaaat tttataggag gactttctca tgcccaattt
      781 tactacagaa attatggaaa cactaatcaa taaaggtgat ttagatgaat tatttcgatg
      841 tcatttagaa ttagctgtta attcattatt gcaggctgaa ttaacagctt ttcttgatta
      901 tgaaaaatat gatcgtgctg ggttcaattc aggtaattcc cgtaatggga attattcacg
      961 ttcattcaga acagagtatg gagaattaaa tttggtaatt cctagagata gaaatggtaa
     1021 gttttctcaa caaactttac ctgcttataa aagaaccaat gactctttag aaaccactat
     1081 tattcagcta tttcaaaaag gaattactat gtctgaaatc tctgaattga ttgaaaaaat
     1141 gtacgggcat cactatacgc cacaaaccat ttcaaatatg actaaaatag tttctgaaga
     1201 tattattgcc tttaaagaaa ggtccttaga atccagatac tctgtcattt ttatggatgc
     1261 tactcacatt cctttaaaaa gacaaactgt ttcaaaagaa gcagtttata ttgtaattgg
     1321 cattcgatta gatggaacca aagaggttct tgggtttagt cttgctccaa ctgaatctgc
     1381 ttatgtttgg aaagagattc ttcaagacct aaaagaccgt ggtttaaaag aggttttatt
     1441 agtcgtaact gatggtttaa gtggcattaa cgatagtatt catagtgttt atccaaatgc
     1501 tcaatttcaa caatgttgtg tccatatatc tagaaatatc gctcataagg ttcgtgttag
     1561 tgatcgacaa gaaatctgta gcgatttcaa attagttta
//
LOCUS       DAFTHM010000205         1597 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.211, whole genome shotgun sequence.
ACCESSION   DAFTHM010000205 DAFTHM010000000
VERSION     DAFTHM010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.211"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..642)
                     /locus_tag="L7C88_002838"
     CDS             complement(<1..642)
                     /locus_tag="L7C88_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9559607.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGM"
     gene            790..>1597
                     /locus_tag="L7C88_002839"
     CDS             790..>1597
                     /locus_tag="L7C88_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBP9559608.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEVAPE"
BASE COUNT          598 a          298 c          272 g          429 t
ORIGIN      
        1 cataccgcta tttagtcggt caagtacttc ttttttaaaa aaagtattca tcataaaagc
       61 cactacttgc ggatcttcat cataaaattc tgtagcagta cttgaaaaga tgttccaata
      121 aatatctaat gctgcatatt gaatttgtac ctcttttcca gaaaaagact ttctgccatt
      181 attagaaaag gagatagaca aaccgtacaa tgctaaaaat gcattaatct ttttcatttt
      241 cgtatacaaa taagaggcac tatagtttgt ttgctgactt aaactgataa tcgaatttgt
      301 ctgacagctg aacaaagaag tcaagatctg ataactgact gattcgttgc agtatcttcc
      361 aaatagacga taatagcagt aagccggatc aattccttca aaattcaact ttaaaaaagg
      421 tttttgctta tcaatatgca gttctgttag attgagacgc tcaaagtctt gttctaattc
      481 tttgatgtat agtaaaaaat ttgattcaga catatggaaa tgatctgcta aatattgtgt
      541 agtaataaag aaacgatgtt cagataggaa aagaaaaata tctaattttg tattgctttt
      601 tttcttcaag agaaacgttt taatcgcttc ttgagtttgc atgaaagagg ctccttttta
      661 cttaaattgt taaaacttga aaatattact gtttttttca taaatttaga caaaaaaaca
      721 gtaaacatat aggtagaatc tctactatct tatttcttgc atacaaaaaa atcaaggagt
      781 gagagagtta tgagatattc aaccatctta atatcaacat ttgcagcctt aagcttatcg
      841 cttactataa atcagacagt ccacacagag gagatagaaa cagccaaatg gacagaaacc
      901 aagtgggcca acgtcaatcg aattaccttt caggatgaat tttcatcctt caattcagga
      961 gtcgcaaaat taagaaaagg acaaacagcg accatcaaag caaaaattga ctattcagga
     1021 gacttagcac ctatactaca atcagctgtt acatttgaga atgttgatcc cgctttgtcg
     1081 attggctatg acgagaacac tttgactatc caacacaagc aagcgatatt taccttcacc
     1141 gttacattaa atcaggactt gttaaaacca gcgcttttta ctgtcaaggt atcagatgga
     1201 ctaccgaacg atcatcatca tttaacgccg tatagtcagc ggcagacaat tgagcaagat
     1261 tcagctatcg actcaggagg agatcttgtt gaagaaccaa cagataaacc agaaaatgaa
     1321 aataagccag aagtaccgcc tacagaaaat ccagacggag aacagaaacc ggaaatagaa
     1381 cctggagaag aacccgatac agaaactcaa ccagagccag acaatgaatc aaaacctgaa
     1441 ataacccctg gagaaaaacc agatgtagac ccagaagaaa aaccagatgt gactccagaa
     1501 ccagatacgg attctggaaa ccaaacagta ccggaaacaa atccagacac agataatgaa
     1561 actgaaaatc cagaaaaacc agaggtagcc ccagaag
//
LOCUS       DAFTHM010000206         1573 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.212, whole genome shotgun sequence.
ACCESSION   DAFTHM010000206 DAFTHM010000000
VERSION     DAFTHM010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.212"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT          594 a          179 c          320 g          480 t
ORIGIN      
        1 attatcgaac acctttggaa gtatttttga gttacgtaag tattgatgat ctgtctaatt
       61 taatttgaca attaagaaag tattaacttg ttttgtgaaa aagagaattt gaaaaacgat
      121 tggcgaacaa atgctcggta ggtatggtat aaatacagag ctaattggtg tgatgaaatc
      181 agatattcgc gtgagattca gtaaagtagg agttcgaaaa cagctaggtg acaaacagta
      241 ttgctttggt acttcggaat ggtttatcaa attcttatca acagttcact tctctttatg
      301 tttgagtgat gattcgttag gttattgctt ggaaagaccg gatgagagta gaagagttta
      361 attttataaa gtgaaaagag gtaatgtacg atatacgtag ggctgaacca atagaggata
      421 agcaaacgat gttacaggcg caaaattcat agcttactgt tttggagata acagaagagg
      481 aaataatgca gaagtaaggc gaaaaaagga cggaagccta acagcatatg aaataaagaa
      541 aaatattata actactgata aatcggtatt gagcaaagta ctaataggag tcaaaaacat
      601 tcataagcta tgagtgtttc ttggctactt ttttattttt atgtatctac aaaagtttcc
      661 aggggcagaa cctgtgatta ttaatggaag aacctcaagt attgtcttaa atcattgtta
      721 tgaaaatgga ttaaaagagt tcatcaaggt gtgattaaca agttactttt cattacatcg
      781 aatttttcag aagttgctta tattggtgat gatattaatg atttatcatg tatgacatct
      841 gtgaagaagc gggaggaata gtagaatgtc caaaaaatgc cacaagaaat gagattgaat
      901 tatctgattt tattgtaact cacagtggtg gtgacgaatc tgtgatagag tttattgagt
      961 ggatattgga atcgatatag tgtagtagta cagaaaaatt atcatacaat taatactagg
     1021 cataagaata ttggcatatt ctagagttaa aagtaactat tcgaaaagga taaggttaga
     1081 attttttgtt ttgccagtgg aagaatataa aaagggcatt ggaaattaat atattagaat
     1141 gctaagcgga gaaaaaaata tatgaaaagt acgtccttgt gatgggatgg aaaaatacac
     1201 ttatttcaaa caacgataat ataattatgt gaaccgaagt atactcgctt ctaattcaat
     1261 cctcaaatcc cgacagtcgc gacttcaaaa aagcgtatag ttttaatgta tccccatatg
     1321 atccgaaaaa tggtaattta caattaacag tttgatgatg ttgaagatgt ggaaatgctg
     1381 aaattaccat gatgagaaac acattaatta aagggaatta attaactaga atataatctg
     1441 attcaatttg aattaagcaa aaaaaggctg agttttaaat aatcgcgaat tgtaaaatta
     1501 agttagaaaa ataaaaaggc atttatggta cactcaaatt gtatttccga cgaaagaaaa
     1561 caaaggagtg taa
//
LOCUS       DAFTHM010000207         1541 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.213, whole genome shotgun sequence.
ACCESSION   DAFTHM010000207 DAFTHM010000000
VERSION     DAFTHM010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.213"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            31..1497
                     /locus_tag="L7C88_002840"
     CDS             31..1497
                     /locus_tag="L7C88_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBP9559609.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          426 a          290 c          326 g          499 t
ORIGIN      
        1 ctgaaaattt aaagaattgg ggtatagatt atggaaaaac agcaagacaa gggcttcttc
       61 gggcagccga agggattgtc aactttgttc ttcactgaga tgtgggaacg atttagttat
      121 tacggtatgc gtgcattact tatctattat atgtacgata cagttgccaa cgggggactt
      181 ggattaccac gagcaacagc attagctatc atgtcgatct acggatcttt gatctacatg
      241 tctagtatcg tcggcggatg ggtatctgac cgagtgttag gagcaaaacg cactgtattc
      301 ttcggtggag ttttcattat gcttggccac atcgtcttgg ctttaccatt tggtgtaagt
      361 acattgtttg tttcgatggc attgattatt atcggaaccg cctttttgaa accaaatgtt
      421 tctggcatgg tcggacatct ttattcaaag actgacttgc gaagagatgc aggattttcg
      481 attttttaca tgggtgtcaa cttaggggca ttattagcac cactaatcgt tggtacaatc
      541 ggtcaagaat ataactatca tttagggttc tctttagctg ctattgggat gttctttgga
      601 ttattacaat acatcatcca aggacgcaag acattagacg gagtgggtac aacaccgccg
      661 aatcctttga caactgaaga acgtaaagga ttcatccgta acttgatcat cgcacttgtt
      721 gttatcgctg cagtattcgg cggggcacaa ctaactggtc atctgacaat tgactttttt
      781 gtcaatacaa tcagtgtatt ggggattatc ttaccgttgt attactttat caaaatgctg
      841 acttcaaaag atgtaactgc tgaagaaaaa ccaagagtat gggcttatat cccattattc
      901 cttgcagcaa tcattttctg gtcattacaa gaacaaggtt catctatctt agctttattt
      961 gctagtgaac gtacacaatc tacgctattt ggtgtaacga tccaagcaag ctggtatcaa
     1021 tcattgaatc caattttcat ctttattctg acaccagtat tcgtaacgat gtggacgaaa
     1081 cttggtgaac gtcaaccatc tacagtagtg aaattctctc ttggactttt atttgcagga
     1141 ttatcgtact tgctattgat gttgccgggt atgctttatg gtacaagtgg aaaagtaagt
     1201 ccattgtggt tgttgggaag tttcttcatc gtggttattg ctgaattgtg tctttcacca
     1261 gttggtttgt ctgtgacaac aaaattagca ccacgagcat ttgaatcaca aacaatcgct
     1321 atttggttct tagctgatgc ttcttcacaa gcaatcaatg cacaaattgc acgcttctac
     1381 acaccgggaa cagaatctgc ttacttcggt attatcggtg cagtagcaat cgtcggtggt
     1441 atcttgctat ttactgtgaa agaaccaatc aaaaaactaa tgggctctat tcattaatca
     1501 atgaacataa aaacaggaat tgcttatttg cagcagttcc t
//
LOCUS       DAFTHM010000208         1535 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.214, whole genome shotgun sequence.
ACCESSION   DAFTHM010000208 DAFTHM010000000
VERSION     DAFTHM010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.214"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(943..1356)
                     /locus_tag="L7C88_002841"
     CDS             complement(943..1356)
                     /locus_tag="L7C88_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBP9559610.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
BASE COUNT          571 a          247 c          226 g          491 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaa
//
LOCUS       DAFTHM010000209         1531 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.215, whole genome shotgun sequence.
ACCESSION   DAFTHM010000209 DAFTHM010000000
VERSION     DAFTHM010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.215"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..392
                     /locus_tag="L7C88_002842"
     CDS             <1..392
                     /locus_tag="L7C88_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559611.1"
                     /translation="LTIGISVTGTTIPTFADSTNEPTTVVDNNQELTPLDRDGIAIGN
                     PTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSRNWKEKRNGYWY
                     YGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            402..605
                     /locus_tag="L7C88_002843"
     CDS             402..605
                     /locus_tag="L7C88_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559612.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            816..1400
                     /locus_tag="L7C88_002844"
     CDS             816..1400
                     /locus_tag="L7C88_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBP9559613.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          539 a          222 c          284 g          486 t
ORIGIN      
        1 ttttaactat tggaattagt gtaactggaa ctacaattcc tacatttgct gatagtacaa
       61 atgaaccaac tactgtagta gataataacc aagaattaac tcctttagat agggacggaa
      121 tagccattgg taacccaact aacgacttaa ctgttactga aaattattta atagtttctc
      181 cattacttgc tctagcagct tctaaaacga tacgagtgac aggaacgatg atttttgata
      241 aagttggttg gccttctaga cctcctcaat cacggaattg gaaagaaaaa agaaatggtt
      301 attggtacta tggaaaattg tatttacaaa gttataaatc agctggaaac aattggattg
      361 cgacttattc aggaacctta actagaaagt agggattttt tatgccagaa tttgtgaaca
      421 caccaaattt ttatcaagat agcgatattc taagtaaaat taatttaccg aaagaagaat
      481 cagctttaca agttcagcga actttacagg agacacaaaa aattcaaaaa tcaatttcta
      541 atctagaaga ttctgaagaa aaaagaaaaa aaagagacca aaaaacatat caaaaagaaa
      601 aataatgatt ttaaaaaaag agtgtctagt cgacattctt tttttctaat tgaaagtgtt
      661 cataaaatca cccatttctg gacactttct ttttttgctt tatttttcaa aaaaacaatt
      721 catttcatgt tcataaaccc ataacaatat ctatgttcag ttaaactata tggataaagt
      781 tatgttacaa taaaattaat gaaggagtga tttttttgaa aataggatac gcccgggtat
      841 ctactggttt acaaaatttg gatttacaag aagacagcct aaataaattt ggttgtgaaa
      901 aaatttttac tgatcatatg agtggggcaa aaagtaatcg accaggatta gaaatggcca
      961 ttgattttgt tcgctctggc gatacacttg tcgtttggcg cttagatcgt ttaggtagaa
     1021 atatggaaga tttgatttca atcgtcaatc gactgaatga gcgtggtgtg agttttcata
     1081 gtattcaaga aaatattacg atggacaaat caagttctac aggacagctc atgtttcatt
     1141 tgtttgcggc atttgcagaa tttgagcgta atttgatcct ggaacgatcc gcagcaggac
     1201 gagcagctgc tcgtgcaaga ggacggtttg gtggtcgtcc tgaaaaattg tctgaacaag
     1261 atttggaatt actgaagact ttagtggata gcggtacacc tattaagact attgcggaac
     1321 ggtggaacgt ctcaagaacc accatttatc gttatttggc aaaaatggag gagaaaaatg
     1381 gaaagacaaa ttctcattag tttttgtcat ttaatgctga aaatttttgc catttatcta
     1441 gaaaagtgac aatagtatga gaattttttg taagtgtcta ctgataactt attctcaaat
     1501 gttgtaagga ttttattcat ttgttaatat t
//
LOCUS       DAFTHM010000210         1506 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.216, whole genome shotgun sequence.
ACCESSION   DAFTHM010000210 DAFTHM010000000
VERSION     DAFTHM010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.216"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..354
                     /locus_tag="L7C88_002845"
     CDS             <1..354
                     /locus_tag="L7C88_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBP9559614.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
     gene            355..903
                     /locus_tag="L7C88_002846"
     CDS             355..903
                     /locus_tag="L7C88_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559615.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            1163..1506
                     /locus_tag="L7C88_002847"
                     /pseudo
     CDS             1163..1506
                     /locus_tag="L7C88_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          594 a          183 c          325 g          404 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aacttcctcc aatgttgaaa gacagagtag aggaagaaca
      541 aaaaaagttg gcgcaccaat cagaaagttt gataaggttt attccaccaa gcatccttta
      601 aaactgtcga ctttgttaaa tgcgacttcc agagttttag tagaaaagta tgagactaat
      661 atgacaagag atgaattgct tagaaaagct ttagatgagt atattaaaca gaatcttacg
      721 caagaagata agcaagattt gtttaatgac gtggtgaaag aactagactt gttcagagaa
      781 aaatatccaa ttgttccaga attagatgat cgtggagaaa taataagaac taccagtcag
      841 ataaaacaag ataccgaaga ctcactgcgc aaagggtggg gaatgaataa taaagttaga
      901 taataatcaa agaagaacta agtaactacc tttaaacggt agttacttag ttcttctttg
      961 atttgcgtga aatagagggg atttattttt ctggttacgt gattaaaaaa tccaaaaaat
     1021 gagcatagga acggttatga ttttagggtg tgttttaatg agatattgtg atttcattaa
     1081 caagtgtatg ataatctgtt gttgagttag taaataagta atagagctaa ctctaaaata
     1141 aaactattag gaggagatgt aggtgaaaaa gtttaaaaag aaaatatatt taggattggt
     1201 tgttggggtg agtatgtttg ggttcatggc tcatactaaa caagtaactg cagatactaa
     1261 ccaaaaagaa aggattatga gccaattaga tgactctcaa ataagtatgt acccaatgag
     1321 ctaattgtca gtttaaaggc tacacaaaga atttcaacag agaaaaataa accgcaaaat
     1381 ttattgggtg taaaagttat ggtggaaaaa gatttgactc ttaggataaa tgaaagcgat
     1441 tataataagc gagatcaagt attattagtg aaattgaacg aagaaattag tgtggaagag
     1501 gcagta
//
LOCUS       DAFTHM010000211         1483 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.218, whole genome shotgun sequence.
ACCESSION   DAFTHM010000211 DAFTHM010000000
VERSION     DAFTHM010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.218"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="L7C88_002848"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="L7C88_002848"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBP9559616.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
     gene            complement(1251..>1483)
                     /locus_tag="L7C88_002849"
     CDS             complement(1251..>1483)
                     /locus_tag="L7C88_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559617.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT          509 a          202 c          263 g          509 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcggctctt tgtcaataag gactgatggg
     1081 ttgtacaaaa tcaaatctga gccagaatgt ggttcattct gactcagatt tgattttgca
     1141 caactcatca gtccttattg acaaagagcc aaaagatgtt ggtgaagttc accaacatca
     1201 aaaagtatag agccgataga aggactgacc ttctgtctca gatttttttg ttatttcact
     1261 tgaatcaatt gattgatcaa aaaaatcctg attttcatgt tctcaaatga tttaaatcca
     1321 taagataatc gtttcagtgt cttgatatgg ggaatcttgg cctctatttt gccattagaa
     1381 tacgggtaaa tcatagcatt gtaaatacct tcttcatacg ttaaaaggtt ttgaagtttc
     1441 gtgcgaagtt gtgcatcaag tgtttcagga agatttttta ata
//
LOCUS       DAFTHM010000212         1439 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.219, whole genome shotgun sequence.
ACCESSION   DAFTHM010000212 DAFTHM010000000
VERSION     DAFTHM010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.219"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            105..1406
                     /locus_tag="L7C88_002850"
     CDS             105..1406
                     /locus_tag="L7C88_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBP9559618.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          474 a          288 c          264 g          413 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttctta
//
LOCUS       DAFTHM010000213         1417 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.220, whole genome shotgun sequence.
ACCESSION   DAFTHM010000213 DAFTHM010000000
VERSION     DAFTHM010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.220"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(150..1337)
                     /locus_tag="L7C88_002851"
     CDS             complement(150..1337)
                     /locus_tag="L7C88_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBP9559619.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          412 a          308 c          249 g          448 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttc
//
LOCUS       DAFTHM010000214         1374 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.223, whole genome shotgun sequence.
ACCESSION   DAFTHM010000214 DAFTHM010000000
VERSION     DAFTHM010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.223"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(40..612)
                     /locus_tag="L7C88_002852"
     CDS             complement(40..612)
                     /locus_tag="L7C88_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBP9559620.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENCVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(628..1233)
                     /locus_tag="L7C88_002853"
     CDS             complement(628..1233)
                     /locus_tag="L7C88_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBP9559621.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          371 a          302 c          200 g          501 t
ORIGIN      
        1 attaagtatt tacctgtctg gttcgctgag acttcttttt taactttctt caattttctt
       61 ctttattcta aaaagcgtac tgcgactgaa accggttata gcttcaactt ccttatacga
      121 tttacctgaa gtaagcagtt catatgcgtg cctcttcttc ggtgtgattg ttgctttcgg
      181 acgtccttct ctgaaattag gattattctt tcttgcaaac atttttcctt cttgggtacg
      241 ttccacaatc atatcacgtt ccatttctgc tacactcaac aacgtccgtg tcaccattcg
      301 ccccatggac gtattttcaa tcgttcctag attcaaaacc ttgatcgtta cgttatcatc
      361 gagtaaaggt tcaatgatct ctaatgcttc tctcgtgtta cgagcaaatc gatcaagctt
      421 cgtaacaact atttcatctc caggcttcag accagccaac agctgattga attttggccg
      481 atcccgtttt gtacccgtaa atttttctga aaaaatattc ttcttctcta cgcagttctc
      541 aagcaactgt tgaatttgtt cttttgtact ttgagaagcg gttgagacac gtgcatatcc
      601 atatttcgtc atttggtcca cctactttta caaatcatct atcgtatact cagaataccc
      661 ttcatagaaa tagctgacat cgattccttt catatataac tcgcgatcgt caattttatc
      721 agtcagagca ttggaaatta gatagcgtat ttccaaatcg tttatgggac ttcgctccat
      781 tgcagaaaga tagtctgctt tatcgattaa gttccaatct acaacttttt gcaattcttc
      841 ctttaaaatg agatccagcc aaattctagt acttcggcca tttccttctc gaaatgggtg
      901 agcgatattc atctccacat atttcttgat aatctcttca aaagaagttt gtggcatctg
      961 atcaatatgc tgtaacgaat gttctaaata cataactggt gcaaatcgaa aatttccttt
     1021 tgcaatattg accgatcgga tttttccggc aaaatcgtaa atatccgaaa atagaaattc
     1081 atgaatttca gataaacctt taaatgtacc aacttcgatt tcatttattt ttccacaatc
     1141 gtacaattct ttcgcttttt gtttactgag tttttcttca accttagcca actcaacttg
     1201 attggttaat cccaatttat tctctaaaat catgcgaaat ctccttaact ttatgacata
     1261 agtttatgaa acactctcaa ccccattata tcgcgatttt gtttatgtgt caaaaactat
     1321 taagtttctg acccccgata gatttttcaa gtgtctctat tttgcacagt ctag
//
LOCUS       DAFTHM010000215         1373 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.224, whole genome shotgun sequence.
ACCESSION   DAFTHM010000215 DAFTHM010000000
VERSION     DAFTHM010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.224"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            191..445
                     /locus_tag="L7C88_002854"
     CDS             191..445
                     /locus_tag="L7C88_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBP9559622.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEDNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="L7C88_002855"
     CDS             446..763
                     /locus_tag="L7C88_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBP9559623.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          493 a          196 c          266 g          418 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaagacaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accttaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acttccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat ata
//
LOCUS       DAFTHM010000216         1372 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.225, whole genome shotgun sequence.
ACCESSION   DAFTHM010000216 DAFTHM010000000
VERSION     DAFTHM010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.225"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            122..>1372
                     /locus_tag="L7C88_002856"
     CDS             122..>1372
                     /locus_tag="L7C88_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBP9559624.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          428 a          271 c          261 g          412 t
ORIGIN      
        1 gctctatact ttttgatgtt ggtgaacttc accaacatct tttttgtata aaaaaatata
       61 gaaaagacac cctgaaatcc tttagaatta atttggctac caattcatag gaggattcaa
      121 gatgtctcat actcagctta tcaaagatac cctaaatatt ctagacctaa atatctattt
      181 cgaggaaaat tgtttaacta aagaaaaata caaagggcaa atttgcttga tttacaaagg
      241 aactcttctg tacaagccag aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat
      301 cattcgttgg gggacgacaa ccgttcggtt gttactgaat gatgtgtctg agtatcgcac
      361 ttatctggag ctgaagaaac aacgatttaa atgtaagtct tgccaaagaa cattcgtagc
      421 ggatacctct gttgctgaaa aacactgttt cattagtcaa aaagttcgtt ggtctgtcat
      481 tgctcgctta aaagagaata cttccatgac ggaaatcgct cgtcagaaaa atatttccac
      541 ttcttcggtc tatcgtgtca tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac
      601 tttgccaaag gtcttatgct ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat
      661 gagttttatc atgatggacg gacaaagcca tgcattattg gatattgtcg aaaatcgacg
      721 cttgccttat ttagaacgct atttttctcg gttttcatta gcgactcgtg aagccgttca
      781 attgattgtt attgatatgt atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa
      841 tgctcagttg atcatcgatc gtttccacat cgtccaacat attggcagaa ctttcttgaa
      901 tcatcgagtg aaagaaacca cggtacgact taaaggaaat tcccactctc aacgagggtt
      961 agggaaaaaa ttgaagcgct attggaaact cctacaaaaa gaagaagcaa agttaaacta
     1021 tgaaaaacgg gtttggcgtg ccagttttaa agattatttg actgaaagtg agattgccga
     1081 tcgactgtta gctgcttgtc ccaacttacg ccaaggctat cagttatacc aagacattct
     1141 ttatgcggta aagaaaagag atcagtcact atttgaggat tgtttaacta gagacattag
     1201 cggtctgcca gaaacctata caaccacttt acgaacgttt aaaaagtttc tgccacagat
     1261 ccaaaatgcg cttcactaca gctattcaaa cggaccattg gaatgcttaa acaaccacat
     1321 caaagtatta aaacgcaatg cgtacggctt tcgcaacttt tacaatttca aa
//
LOCUS       DAFTHM010000217         1349 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.226, whole genome shotgun sequence.
ACCESSION   DAFTHM010000217 DAFTHM010000000
VERSION     DAFTHM010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.226"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..347)
                     /locus_tag="L7C88_002857"
     CDS             complement(<1..347)
                     /locus_tag="L7C88_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559625.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAIL"
     gene            635..1288
                     /locus_tag="L7C88_002858"
     CDS             635..1288
                     /locus_tag="L7C88_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBP9559626.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          504 a          168 c          242 g          435 t
ORIGIN      
        1 atgagaatcg cctgcttcag ttcctttgtt agttgatgat gttcatcaac taagtccgtt
       61 ttcgcagaaa aggtctgccc acaatcatag catagaaaac gggtacgttt taattctaaa
      121 atagtcaact tttctttgac tttcaatatc tgagtacgtg tcgtatagga accgttgcgg
      181 ataatacgaa tcgatccaca gtgttcacaa tgggaaggtg agtcatccaa tctcccttta
      241 ataaactgcg cttgaacgcc tttatattct ttttcaatca gccattcttc atcaaaaaat
      301 aaatgtttat ctgttaatcc gagtaatttt ctagtatgat tatccataga gcgactcctt
      361 tggtagggtg atgttttggt cgactaaatt ttaccaaaag tgagtctctt tttgagttga
      421 aacgaagaaa aagtgttagt agaaaatcgc cttcgatttt ccaacaacac aaaatattat
      481 agaacccttt attctaaagg atttcaaggt gtctgtttgc atttattaga aaaaagaaaa
      541 agtattggca acagaaggtg tcaccaacac tagatattat agagccataa tatgctgtat
      601 aatatctagt gtataggctt aagtggaggt atatatgaaa atattaactg ttgaagatga
      661 taatatgata agagagggaa taagtgaata tctttcagaa tttggatata ctgttattca
      721 agctaaagat ggaagagaag ccttgtcaaa atttaatagc gatataaatt tggttatctt
      781 agacattcag atacctttta taaatggttt agaagtgttg aaagaaatta gaaagaaaag
      841 caatttacca attctaatct tgactgcatt tagtgatgaa gaatataaaa ttgatgcatt
      901 tactaattta gtagacggat atgtagaaaa gccattttca ttgccggtct taaaagctag
      961 aatagattct ttaattaaga agaattatgg acatttagag aagtttgaat ataaggatct
     1021 atcggttaat tttaatagct atacagctaa aataaatggt gaagaaatag atgtaaatgc
     1081 aaaagaacta gaagtattaa aatgtttatt ggataataat ggacaagtgt taacaagaat
     1141 gcaaattatt gattatgtat ggaaagatag cgaagaaact ccttatgatc gagtaataga
     1201 tgtatatata aaagaactta gaaaaaaatt acaattagac tgtataacta ctataagaaa
     1261 tgtaggatat aaattggaga gaaaatgaaa aaattaaaga tatttccaaa aatgttcata
     1321 caaatatttt ctgttcttgg aataataat
//
LOCUS       DAFTHM010000218         1336 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.228, whole genome shotgun sequence.
ACCESSION   DAFTHM010000218 DAFTHM010000000
VERSION     DAFTHM010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.228"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..221
                     /locus_tag="L7C88_002859"
     CDS             <1..221
                     /locus_tag="L7C88_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBP9559627.1"
                     /translation="NKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIITGF
                     GAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            218..1237
                     /locus_tag="L7C88_002860"
     CDS             218..1237
                     /locus_tag="L7C88_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBP9559628.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLSDGTNHSHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RPDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
BASE COUNT          449 a          244 c          275 g          368 t
ORIGIN      
        1 ataataaaac gttcgaagta ctaaaatggt tcgcactggt aattattccc gcactagcta
       61 ctttcgtggg gttagttggt aaagcgctca attggcagta cacagatatc tgtgttgtca
      121 tcattactgg ttttggcgcg tttttaggga gtgtgttggg tgtatcaaat cgaacctaca
      181 aaatgttctc ggctgaaagc gaagaaggag gaaacaaatg aaaaagaaaa ttactattac
      241 tgcgatgagc ctgttaacgg ctcttttttt attgccaatt aacggatttg cctatactat
      301 caacaatgaa tttaatttgg gcgcaaatga aggtagctca caagtagcaa ataatcagta
      361 tattttactg catgaaacgg ctaatgaaac agcaacagga cgcaatgaag cgcagtatat
      421 gcaacgttca tggactagcg cttatactgc ttatattgtg ggagacggcg gaattgttta
      481 ccaagtcgga caacctggtt atgtacagta cggtgctggt tcatatgcta atgccaatag
      541 tcctgtgcag attgagttac aacacacaca tgataaagca acttttgaaa aaaactataa
      601 agcatacgtt gaattggcta gagattcagc aatgaaatat ggtattccat taacattaga
      661 cacgccttat aaccaaccag gaatcaaatc acatttatgg gtaactcaaa acatttgggg
      721 cgatcacact gatccgtatg gatacttatc agaaatgggt gtaagtaagg aaaaactggc
      781 ttacgattta gctcatggat ttacagacga aaacccaacg acttctgaga acaagcctgt
      841 cattgatcca acccgagcag gtgcagcaaa tccaacttta tcagatggaa cgaaccattc
      901 tcacattgat cagtttggag aaatcgaaaa tgcgaactta cacgtcgctg gatggcacat
      961 cgctaactat aagtacgagt atattttcat tatggactac aatactggga aagaattagc
     1021 tcgagtaaga gctgatggaa tttatagacc ggatgtaaat caagcttata atacttctgg
     1081 aaatgttggc tatcatgtat cttttaacat gcgtaacttc cctaataaga aagtctatgt
     1141 catgatgcgg gcaacgaatg atccagaggg aaacactaaa ggcggtgcgc aagatttcca
     1201 tgacaaacgt tggtatttaa atattcctaa acgataaaaa tagctcctcg ttgaggagca
     1261 ttacataact atattgacaa ctataaaaat cattcgataa aatagtgatg ttatcgcata
     1321 tcttcactat caccca
//
LOCUS       DAFTHM010000219         1323 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.229, whole genome shotgun sequence.
ACCESSION   DAFTHM010000219 DAFTHM010000000
VERSION     DAFTHM010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.229"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..682
                     /locus_tag="L7C88_002861"
     CDS             <1..682
                     /locus_tag="L7C88_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBP9559629.1"
                     /translation="QLLFSYISPTKLKKTGVVDLPVKAIINYMDVDQNLETELKTIVN
                     TLQRQAVYEISNLDKKYKTYTTVSAIDRIHWDLEEHSVSFSFSEDVIPLIVSIKKKYP
                     FFVFEDLASFQKKYSIVLYKYLAMYYKKYLIAKNKGDFEKAEIYKNPLIEIVKIREIT
                     KTENEYKTISNFDRRVLRESVEEINEKSMLNIDFAKVRKGRNYNFAVQFNISSEFDEK
                     TYREKKLG"
     gene            874..1272
                     /locus_tag="L7C88_002862"
     CDS             874..1272
                     /locus_tag="L7C88_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBP9559630.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
BASE COUNT          483 a          167 c          249 g          424 t
ORIGIN      
        1 tcaattgctg ttcagttata tctcacccac aaagctaaag aaaacaggcg tagtagattt
       61 acctgttaaa gcgattatta attacatgga tgttgatcaa aatcttgaaa cggaactaaa
      121 aaccatagtt aacactttgc aaagacaagc agtttatgaa atttcgaatc tagacaaaaa
      181 atataagacg tatactactg tatctgctat tgatcggatt cattgggatt tagaagagca
      241 tagtgtatct ttcagttttt cagaagatgt aattccctta attgtctcaa tcaaaaagaa
      301 gtatccgttc tttgtttttg aagacttagc atcttttcaa aaaaaatata gcatcgtgtt
      361 atacaaatat ttggcgatgt attataaaaa atatcttatc gccaaaaata aaggagattt
      421 tgagaaagct gaaatatata agaatcccct gattgaaata gttaaaattc gtgagattac
      481 gaaaacagaa aatgagtata aaacaatatc gaattttgat agacgtgttt taagggaatc
      541 agttgaggaa attaatgaaa aatcaatgct gaatattgat tttgctaaag ttagaaaagg
      601 cagaaattac aattttgctg tccagtttaa tatttctagt gagtttgatg aaaaaactta
      661 tagagaaaaa aaattaggtt aatgcaaaat atatcttact cgtttgaaga tgcttcagac
      721 gtatgctaag atatatagtg ccttgggagc aaggtattaa tctcctttag aggttaatta
      781 gcttgtgatc gcctatcaat ttttttggta ggcgattctt ttttttgaaa caaaaaagca
      841 aaaattattt tttaattaga gaggtgcaat gcgatgaaat actttttttg tgcagtattc
      901 gaatggaaag gaaatgaata tgcagttaaa ttcccagatt ttccagactt atatacacat
      961 ggtgaaactt tagaagatgc ttttgagatg gcgcaagaag tattggaagg atacttggtg
     1021 cttttagagt tgcaagaaaa agaaattcca tcgcctacgc ctgttcaaga gttaaatgca
     1081 agaatcaagc gatctgagaa tgttaattta tttgtcgtaa aagctaatac gaaagttgct
     1141 aaagctcgaa acaagcaaaa ttatgatcga aaatcagtga ctgtggaaca ctatttaaat
     1201 gttttagcgg ctgaagagaa tattaatctg tcgaaagctt tgaatgattt gttgagagaa
     1261 aagttgattt gatgtctctc agatgatcat attaagcaaa aacagcttgt tttaggacgt
     1321 atg
//
LOCUS       DAFTHM010000220         1249 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.230, whole genome shotgun sequence.
ACCESSION   DAFTHM010000220 DAFTHM010000000
VERSION     DAFTHM010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.230"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..1244
                     /locus_tag="L7C88_002863"
     CDS             <1..1244
                     /locus_tag="L7C88_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBP9559631.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          412 a          223 c          269 g          345 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacg
//
LOCUS       DAFTHM010000221         1246 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.231, whole genome shotgun sequence.
ACCESSION   DAFTHM010000221 DAFTHM010000000
VERSION     DAFTHM010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.231"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            200..742
                     /locus_tag="L7C88_002864"
     CDS             200..742
                     /locus_tag="L7C88_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559632.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="L7C88_002865"
     CDS             898..>1246
                     /locus_tag="L7C88_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBP9559633.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAFTHM010000222         1238 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.232, whole genome shotgun sequence.
ACCESSION   DAFTHM010000222 DAFTHM010000000
VERSION     DAFTHM010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.232"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..1072
                     /locus_tag="L7C88_002866"
     CDS             <1..1072
                     /locus_tag="L7C88_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9559634.1"
                     /translation="THDNTVSRKGKHLSYSERCQIAILKKEGYSNRQVAKVLGRVPQT
                     INNEIDRGTITQLKRQTQNGKVYDTYYSVYDADAGQAFYEKQRLNCGRRPKWANTNAF
                     IDWADDKMLNEKWSPDVVVGFARKHELFDCAIIPGTTALYQWIDRGIMRTKNMDLLEK
                     LSRKIKAVRPGHRPNKRVLGTSIEERPKEVETRETFGHWEIDTVVGNKTKSDAVLLTL
                     AERQTRFEVILKLNGKDTESVDQAVQQLRERAGANFDQLFKTVTSDNGSEFSGLHDAL
                     QDVADVYFSHPYASWERGTSENQHKLIRRFVPKGSPISEVSENQILRIQRWMNDYPRK
                     ILGYATPHDTFVQAFKQERLVA"
BASE COUNT          365 a          296 c          304 g          273 t
ORIGIN      
        1 aacccatgat aacacagttt cacgcaaggg aaaacatctt tcctactcag aacgttgcca
       61 aatcgctatc ctgaaaaagg aaggctattc caaccgtcag gttgccaaag tgctgggacg
      121 tgttccgcaa accataaaca atgagattga tcgcggaacc atcacccagt taaaacgcca
      181 aacgcaaaat ggaaaagtgt atgacaccta ctattctgtt tatgacgctg atgcaggaca
      241 ggccttctat gaaaagcaac gactgaactg tggcagacgc cccaaatggg cgaacacaaa
      301 tgccttcatt gattgggcag atgacaaaat gttaaatgaa aaatggtcgc cggacgtcgt
      361 ggtcggattt gccagaaaac acgagctgtt cgattgtgcc atcattcctg gcacaaccgc
      421 tctttatcaa tggattgacc gcggaatcat gcgaacaaag aacatggact tgcttgaaaa
      481 actgtcccgt aaaatcaaag cggtccgccc aggacaccgt cccaacaagc gtgttctcgg
      541 gacgtcaatt gaagaacgcc ctaaagaagt tgaaacacgg gaaacgttcg gtcattggga
      601 aatcgacacg gtagtgggaa acaagaccaa gtcggatgcc gtgctgctga cgctggctga
      661 acggcagaca cgctttgaag tcatcctaaa gttgaacggg aaggacaccg aatcggtgga
      721 ccaagcggtt caacagctaa gagaacgggc tggcgctaac ttcgatcaat tatttaagac
      781 cgttacatcc gacaatggct cggagttttc tgggctacac gatgctctgc aagatgtagc
      841 tgacgtctat ttcagccacc cctatgcttc ttgggagcgt gggacgagcg aaaaccagca
      901 caaattaatt cgccgtttcg tccccaaggg aagcccgatt agtgaggtga gcgagaacca
      961 gattttgcgg atccagcgtt ggatgaacga ttacccgcgg aaaattttgg gttatgcgac
     1021 accacatgat acattcgtcc aggcattcaa gcaagaacgg ttggtggctt gacccattat
     1081 tccttgataa cgatcctcac tcgggacatg gcttcatgtc tggaaagctg gcctggggcc
     1141 agaatcgtct gaagactatc atacctcagt tcattatcaa ggcctcactg atttagaata
     1201 acgaggcagt tacggtatca aacaaatgag ttacctgt
//
LOCUS       DAFTHM010000223         1193 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.234, whole genome shotgun sequence.
ACCESSION   DAFTHM010000223 DAFTHM010000000
VERSION     DAFTHM010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.234"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..1076
                     /locus_tag="L7C88_002867"
     CDS             <1..1076
                     /locus_tag="L7C88_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBP9559635.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DAFTHM010000224         1165 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.235, whole genome shotgun sequence.
ACCESSION   DAFTHM010000224 DAFTHM010000000
VERSION     DAFTHM010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.235"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            143..991
                     /locus_tag="L7C88_002868"
     CDS             143..991
                     /locus_tag="L7C88_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBP9559636.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
BASE COUNT          399 a          205 c          192 g          369 t
ORIGIN      
        1 accctcatta tacaaaaaaa tttttttgta aatagatttt acaaaaatat tttttgtttg
       61 attttttcct actctccttg tatctttaac attaatgaga acggaaaaaa tgataatctt
      121 attatgaaaa tgaggaattc tcatgagcgt ctccataaga ctacaaatca aaacaatgta
      181 caacgacttc agcccaaaag aacaggctat cgccgattat attttagaaa atccaagcaa
      241 agtaagtcat agtcctatta gcaatttagc aagtgaactg ggcattgctg actctacttt
      301 ttttcaattt acaaaaaaac ttggttataa tggatttaaa gattttaaaa tggccatgtt
      361 gatccaagaa aatgatctat ctgctatttc tatccacgaa aatattcaga aaacagatac
      421 tgagctcact atggcgcaaa aggtgttcga gtctagtatt tcaactttaa atgacacaaa
      481 aaagttgtta caacaaaagg atctaaaaaa agcggctact attatcaatg aatctaaacg
      541 tgtctatttt ttcggtgttg gcggttcaga gattgtagca actgacgctt atcataaatt
      601 tttgcgttcc cctatcgcaa cttctcacag cacggattac catattcaat tgatggaagc
      661 ttctttattg acggaaaaag actgtgctgt tttgatttct cacacagggc aatcaaaaga
      721 aacaatccat attgctgaaa ccgtaagaaa aactggagca aaaacaatcg ttattactag
      781 ccaagctaat tcttcccttg ctaaacttgg cgatgtcgtt tttatttcta tttctgaaga
      841 aacagaattc cgatctgaag ctttagcttc ccgtatttct caactaagca ttttggactc
      901 tctatatgtg attttgatgt tttacaacga aaaagaatca cgtcgttcta tcgctaaagt
      961 tcgacatact atttctgaaa tcaaagaata gcaccataac agaaaaagcg aaaaatccat
     1021 aaaacaaaaa aagccactac caaatatttg gtagtggctt ttttggttct gcaagggtgg
     1081 tacagaacat caatagtcgg tgggttagaa cgtatgtcat cgcatctttg gagaaggttg
     1141 tattggtatt attcgagtta cttgt
//
LOCUS       DAFTHM010000225         1159 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.236, whole genome shotgun sequence.
ACCESSION   DAFTHM010000225 DAFTHM010000000
VERSION     DAFTHM010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.236"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(257..1129)
                     /locus_tag="L7C88_002869"
     CDS             complement(257..1129)
                     /locus_tag="L7C88_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBP9559637.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT          317 a          276 c          225 g          341 t
ORIGIN      
        1 atttgagtgt aacataaatg gcttttttat ttgtctcgct taattataca aacggcgtgt
       61 aaaaaactat tgcacaatac aagtggccta cggctatcga aatttccata actttcgagc
      121 aagaatttat ctcattcaag gcttgatctt ccaagtaaaa caaaaaccag ttaagcactc
      181 tgcctaactg gttatgacta aattttcagt tgtatctttc tctaccaaca ctaaatgtcg
      241 aagagccttt tttcgtttat gaatgtaaga ccgcttctcg agccaatgcc aaacaaccga
      301 gcgttccagc gttgtcttct aatgctgggg tcacgatata tttgcttaac tcaggtgttt
      361 cgacataccc attgaccaat tttgcaaatg cgtcgtggac gttttgcagc atatggcgtt
      421 gtttcatcac accaccgcca aaaatgatca catctggaga aaacatcaag gttgtattgt
      481 aggcacattg agcaatatag gaggcttcga tttcccaata aggatcatct tctgcaacct
      541 cttgtccttt tttccctaag cgtttttcga tggcgggtcc agcggccatc ccttctaaac
      601 agttgccatg aaatggacag ctgccagcaa agtcatcttt tggatgaggg acgacgagca
      661 tatgccccat ttctggatga ctaaaccctt cgataaagcg cccttcttgt aaggcaccgc
      721 cgccaacacc cgtaccgatc gtatagtaaa cgacactgct caatcctttg ccactgccga
      781 agacatactc accataggca gccgcattga catctgttgt ccaagaaatc gggatcggaa
      841 attctttttt catggtaccg atgaaatcaa aattttgcca tgccaatttc ggggtcgagg
      901 taatgtaccc ataagtggcg gaatcgcgat ggatatcgat aggcccaaat gagccaatcc
      961 caatccctgc taaatctgct tggtattgtt tgaagaagtc aatgactaaa ggcattgttt
     1021 cctcaggtgt cgttgtcgga aagctcactc tttccttgat cgtcatttct tcatcgccaa
     1081 tggcacacac aaattttgtg ccgcctgctt caattgcacc gtatagcata gacatttctc
     1141 cctttatttt agaatgaaa
//
LOCUS       DAFTHM010000226         1133 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.237, whole genome shotgun sequence.
ACCESSION   DAFTHM010000226 DAFTHM010000000
VERSION     DAFTHM010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.237"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(18..923)
                     /gene="xerC"
                     /locus_tag="L7C88_002870"
     CDS             complement(18..923)
                     /gene="xerC"
                     /locus_tag="L7C88_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBP9559638.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
BASE COUNT          336 a          231 c          194 g          372 t
ORIGIN      
        1 tgttcttttc cttattttta cgctcttgga tggaaagaac gatagttttt ttgtaaactt
       61 tcttttgtta catgggcata gatctgggta gtcgataaat tggcatgtcc tagcaattct
      121 tggactgtcc gcaaatctgc cccattattt aataaatgag tagcaaatgt atggcgcagc
      181 atgtgaggat ggatatcact atccaaactg ctttttttga tcatttgatt caagacatat
      241 tcaattccag taggcgtgat tggttttcca tgatgattca caaaaacgat atcatgctct
      301 tcgtgatatt ttgtcatcaa tacctggcgg ccttccctga aatattcttg cagagcatct
      361 tgagcaaaag aacctagagg agcatatctc tctttgttcc ctttaccatg gatcaacatg
      421 acctctgaat caaaatcaat gtctgatacc gacaaactgc tacactcact taaacggatg
      481 cctgacccgt aaaggacttc cagtaaagcg cggttcctca aatccaaagg actatctcct
      541 gctacgctgt caaaaagtgc ttgcatttca ttttcataaa aaaaacgtgg cagtctcaaa
      601 tttttctttt tgagatgaac gtaagaaaat ggattttctt ttatcacttc ttctttgaga
      661 agatactgat aaaacgaacg taggctggct atcttgcgac tgatagaatt tctgctatag
      721 ctaggacgat gatcagctaa tgcactcaaa tagacacgaa ccgtaaaata ttccgccttc
      781 agcagatcag cgtctccaga ttcctccaaa aaatgtttga aatggagaat gtcttcttca
      841 tatgcttctt tcgttttttc tgaatatcct ctttcgacaa tcaaataacg caaaaatttt
      901 tgttcccacg tggcttctgt cattttctca ccttcctttt gtcccagaga ataatttagc
      961 acagcgttta taaaaagaca aataaattgt cagaatttaa ccaatatttc taagtttgtt
     1021 cacaattggc gcaattcctc acattttgtt tgagaaattc ttaagaaaaa cgcaagaaaa
     1081 agggctctat aatttatggg actgatgaat cagaattgat tcttcagccc cat
//
LOCUS       DAFTHM010000227         1128 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.238, whole genome shotgun sequence.
ACCESSION   DAFTHM010000227 DAFTHM010000000
VERSION     DAFTHM010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.238"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            123..815
                     /locus_tag="L7C88_002871"
     CDS             123..815
                     /locus_tag="L7C88_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBP9559639.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
BASE COUNT          496 a          128 c          165 g          339 t
ORIGIN      
        1 atttctctat cctttttaaa taatttttta gacaaaaaac agaaagtgtc taaagaaagc
       61 ttgacgaaga aaataatttt taataactta tttaaggaaa ttttttgaag gagaagataa
      121 aagtgagaaa aaagattatt attaatgctg gagtaattat aggattgatg ttagtaattt
      181 tctccggaaa gcaatatgct gataatattt tattatgggg aggggaagat aatattgaaa
      241 agatcaacaa caatttaact atattagaca cagctctaga aaataaagag caaaaaatta
      301 gtattttaaa ttcacaattg tcttcaaaca accaaactct tgaacaacta agaactaata
      361 ttgaagtttc caaacaaaaa gtggcatctt tagaaaacga caagaatcaa ttagtatcag
      421 agaaaactaa tttagaaaat caattgtcag caaaagactc tgaattgcaa ggaaaacaaa
      481 atgaaattaa tgcgaaaata gacgaaatta accaaaaagt agctgaaata aatcgattaa
      541 atagcgattg gaataatcgt ttacaaaatg aaaagaacaa atttaatgaa gaacaatcta
      601 ctattaatag tttaaaccag caaattaatc aaatgttgag tgaaaaaaat aacattcaaa
      661 atcaactgca agctactcag caaaagctag aagaagaaaa gtcaaaaaat agtagtttga
      721 ataattacat tgaaaagctt caaaaagcta aaaatgatgt agaggatacc gcaaataaag
      781 cacaacaaat tgtaaatgaa catacaatcc aatagatata gttttaattt aacaaatggt
      841 atgtttggag ataatgagat agaatataaa tgtcataata ttatacaatc taaacaccgt
      901 ttccttttct atttttgatg acatcagtat atagctactc gaaagagtag tctttttatt
      961 attctcgctt attattgata tgaaaatttc gatttgacaa aaggtaccga ataattttgt
     1021 aatatgaatt attatcaaga agtaattatg atgataacat atggaaacta gttagtaata
     1081 ataacaggtg attaaacttt tgaacgactt gtaattctat attttttc
//
LOCUS       DAFTHM010000228         1117 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.239, whole genome shotgun sequence.
ACCESSION   DAFTHM010000228 DAFTHM010000000
VERSION     DAFTHM010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1117
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.239"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            226..840
                     /locus_tag="L7C88_002872"
     CDS             226..840
                     /locus_tag="L7C88_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBP9559640.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
BASE COUNT          398 a          188 c          183 g          348 t
ORIGIN      
        1 cgaaatcaaa actaagaaaa cgttttctta ataaatctta acagataaat caagttatat
       61 actagaaaat tcataaaata tatttttaat gtcataatcg tttaaatttt cttgattgac
      121 atttatttac aaaaaatatt gccatttaaa aagaaaagtg acatatggct tcctcgtgta
      181 tgattagggt gtattttaaa tagttgcaga aagtaggtaa aagttttgag agttgcatac
      241 atacgtgtct catcgatcga tcaaaatgaa caacgccaga ttgaagaaat gaaaaaattc
      301 ggtgcagaga gaattttcat cgagaaacaa tctggcgcaa cgattactca tcgacctgtt
      361 ttccaagaag cattagatta cgtccgagat caagatattt ttattgtgga agctattgat
      421 cgacttggaa gaaattatga cgagatcatc gcttcagtca attacttgaa gaagaaaaat
      481 gtgaagctga tcattactag tttaccgatc atggctgaag caattggcaa tcctctcctg
      541 gataaattca ttaaggatct gatcatccaa attttggcca tgatcgctga acaagaacgg
      601 actgaatcga aacgtcgcca ggcacaagga attaagatcg caaaagcaaa cggcgtctac
      661 aaagggcggc ccaaattata cagtgcagac gcaaaagatc cccaacgtcg ccttgtttac
      721 aaaagcatcg ttgaagatct taaaaatggt gttgcgattg ctaagattgc taaagactac
      781 aatgttacga gacaaaccgt gtatagaata aaaaaagaca gcatggtcaa tgacaaatag
      841 ttgatcatgc tgcttttatt atcttctcat ctttaatttc ctacatataa ttactatcta
      901 taaaattaag tcttactcag aacagataaa gcataaaatt ccaacaaacc attttttact
      961 taactaaata aagagtctgt taatataatc ttcacttatt tacgttaatc ccctactgta
     1021 tttgttggtt ccttatctat attttctaca aaatccttat tatcttgtga tttagcttcg
     1081 tataattctt tgtatgtcga cacattggtt atactaa
//
LOCUS       DAFTHM010000229         1096 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.240, whole genome shotgun sequence.
ACCESSION   DAFTHM010000229 DAFTHM010000000
VERSION     DAFTHM010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.240"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            78..>1096
                     /locus_tag="L7C88_002873"
     CDS             78..>1096
                     /locus_tag="L7C88_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HBP9559641.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHE"
BASE COUNT          367 a          201 c          213 g          315 t
ORIGIN      
        1 taggtattaa aaaacatatc gttctctagt atgattaaat cacgacaaaa taaacaactg
       61 agaggacgat atgctatatg aatgattcta tcaaaaaaat gctgcgatta atagagaaag
      121 atttgatgat tacagaggtc tcttacgaga cctttcagaa gaaaaagacg ttgatcgtcg
      181 atgctgtttt ctcacctgct ccccatacct gtagaaattg tggttctact gtggtagatg
      241 gaaacgggaa agtaattgta gtgaaaaatg ggaagaagga aacgattgtc cgctttgaac
      301 aatacaatca catgcctttg gttatgcgct taaaaaagca gcgctatacc tgtaaaaact
      361 gtcgaaccca ttggacggct caaagttatt ttgttcaacc cagacattca atcgcgaatc
      421 atgtcagata taaaattgct tctttactga ctgaaaaagt atctttatct tttattgcga
      481 aaaattgtca ggtatctttg accaccgtta ttcgtacgtt gaaagagttt aaaagctact
      541 taccaaagca atctaagagg attctcccca gagtattgat ggttgatgaa tttcgttcgc
      601 acgcttccat agaagataaa atgagcttta tttgcgcaga tggcgaaaca ggacaattaa
      661 ttgatgtctt gcctacgcgt aaattgcctc gattaacaag ctatttctta ggctgcgcta
      721 atcctgaaga agtaaaattt ttagtcacag acatgaacgc cgcctacttc cagcttacca
      781 aacgtattct gccaaatgcg aaagtagtga ttgatcggtt tcatattatc aaacacatga
      841 atcaagcctt taatgagttg cgtatccgtg aaatgaatga acttcgtaaa gtaggacaga
      901 aaagtcaggc agaaaaactg aaaaagaact ggcgcttttt gctaaaaaat cgtgcaaaca
      961 tcaaccatta tgaatacaaa acatggaaaa gttttcgagc accaaaatac ccatttctta
     1021 cggaagcgat gatgattgat cgattgcttg gcttttctac gtccctgaag gaggcgtatc
     1081 cctattttca tgaatt
//
LOCUS       DAFTHM010000230         1090 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.241, whole genome shotgun sequence.
ACCESSION   DAFTHM010000230 DAFTHM010000000
VERSION     DAFTHM010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.241"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            50..199
                     /locus_tag="L7C88_002874"
     CDS             50..199
                     /locus_tag="L7C88_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559642.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            196..642
                     /locus_tag="L7C88_002875"
     CDS             196..642
                     /locus_tag="L7C88_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559643.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            644..781
                     /locus_tag="L7C88_002876"
     CDS             644..781
                     /locus_tag="L7C88_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBP9559644.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            819..>1090
                     /locus_tag="L7C88_002877"
     CDS             819..>1090
                     /locus_tag="L7C88_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559645.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKT"
BASE COUNT          405 a          172 c          222 g          291 t
ORIGIN      
        1 gattatacct ttgcaattac ttacacgatt tagaaaagcg tgaatcgata tgaaggcagc
       61 atatagacca attgaacctt acggattcga gcaaatcatt gtgaatgatg aagaacattt
      121 accggaagaa tgcacagaag tcgaaccacc gattccaaat tggaaaccga aattcaatta
      181 ctgggaggga aataaatgaa aaacatttgg aaatatggac gtactggcgg agagtacgca
      241 ggaaaagtat tggacgacat gcttgtatcc gttccttaca cagatcagcc accgcttgaa
      301 ggaattcgtg ctgatggcga accgttaaca atcgctgatc aaatgtttga tcctaaattg
      361 aatcaatgga ttattttagc gaacgcacta gatcacaacg atttaaacaa tctcaaagca
      421 atgtatgagt cgttagaaaa tgagaacggc gatttaaaac agatcaatgc caaactcatg
      481 ctaagcgatg tagcaattaa acaggaaaat actgcattga aagaaaaagc ggatagttta
      541 gcacaaatca attcaaaaat gatgcttgct tcgttacaaa atagcaaaga catttcagaa
      601 attaaagagc aactaaatcc agcttcaaag ggaggtgagt agtatgttta gttttagcga
      661 tgtgaaaatg atgtatgatt ggggctgttt cactaacgaa caagtaatgg ttttcgttcc
      721 gttgtgcatt actgaagaaa aagcagataa aatcattagc aaagaagaga gcgcatctta
      781 attgatgtgc tttttatttt gattcaagga gttgtcacat gattaattta ggggaatggg
      841 gagcgatagc aggatcaata accgctatcg tttctttgat tttattagta ataaaaccaa
      901 ttactgcatc tttctcgaag attactgaga ctctttcaaa agtaagtcac aatttagatt
      961 tgctgactaa agatttagaa tcgagcaaat cagatcgatt gatgattcat gaagaactaa
     1021 agaaacacga tgaaagatta gatacacatg cagaaaaatt ggtagaacac acgcaacaaa
     1081 ttaaaacttt
//
LOCUS       DAFTHM010000231         1069 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.243, whole genome shotgun sequence.
ACCESSION   DAFTHM010000231 DAFTHM010000000
VERSION     DAFTHM010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.243"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..969
                     /locus_tag="L7C88_002878"
     CDS             <1..969
                     /locus_tag="L7C88_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBP9559646.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          368 a          185 c          214 g          302 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DAFTHM010000232         1065 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.244, whole genome shotgun sequence.
ACCESSION   DAFTHM010000232 DAFTHM010000000
VERSION     DAFTHM010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.244"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            78..>1065
                     /locus_tag="L7C88_002879"
     CDS             78..>1065
                     /locus_tag="L7C88_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBP9559647.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPP"
BASE COUNT          360 a          204 c          207 g          294 t
ORIGIN      
        1 taggtattaa aaaacatatc gttctctagt atgattaaat caccacaaaa taaacaactg
       61 agaggacgat acgctatatg aatgattcta tcaaaaaaat gctgagaata acagagaaag
      121 atttgatgat tacagaggtc tcttacgaga cccttcagaa gaaaaagacg ttggtcgtcg
      181 atgctgttct ctcgcctact cctcgtgctt gtagaagttg tggttctact gtggtagatg
      241 gaaacgggaa agcaattata gtgaaaaatg gaaaaaagga aacgattgtc cgttttgaac
      301 aatacaatca tatgcctttg gttatgcgcc taaaaaagca acgctatacc tgtaaaaact
      361 gtcgcaccca ttggacggct caaagttatt ttgtccaacc cagacattca atcgcaaatc
      421 atgttagata taaaattgct tctttactga ctgaaaaagt atctttatct tttattgcga
      481 aaagctgtca ggtatctttg accaccgtta ttcgtacatt gaaagagttt aaaagctatt
      541 taccaaagca atctaagaag atcctcccca gagtattgat ggttgacgaa tttcgttcgc
      601 atgcttccat agaagataag atgagcttta tttgcgcgga tggcgaaaca ggaaaattaa
      661 tagatgtttt gcctacgcgt aaattacctc gattaacaag ctatttctta ggttgtacca
      721 atccagaaga agtagaattc ttggtgacag acatgaacgc cgcctacttc cagctcacca
      781 aacgtgttct gccaaatgcg aaagtcgtga ttgatcggtt tcatattgtc aaacacatga
      841 atcaagcgtt caatgagttg cgtatccgtg aaatgaatga acttcgtaaa gccggacaga
      901 aaagccaggc agaaaaactg aaaaagaact ggcgcttttt gctaaaaaat cgtgcaaaca
      961 tcaaccatta tgaatacaaa acatggaaaa gtttccgagc accaaaatac ccatttctta
     1021 ctgaagcaat gatgattgat cgattgcttg agttttctcc gcccc
//
LOCUS       DAFTHM010000233         1063 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.245, whole genome shotgun sequence.
ACCESSION   DAFTHM010000233 DAFTHM010000000
VERSION     DAFTHM010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.245"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            96..935
                     /locus_tag="L7C88_002880"
     CDS             96..935
                     /locus_tag="L7C88_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBP9559648.1"
                     /translation="MKMLKVLALGIVVGGVSLAVGTNAEAAENKVWTPRSAEQIKAEI
                     KGNEYTIVWGDTLSAISQATNITVQKLADMNKITNVDLIYAGNKLVFNGNVASVQNSA
                     GETVAQTVIQEKDKVDPNQPVGQGTTSNTQTTPNTTTPTTPAGDQTGTTGGTTTPSTP
                     ENNGGTTQTPTQPGNGGNTGGETTPSNPSTGGGTTTPEEPSNPGGGDQGGNGGTTTPE
                     EPTIVVGEIGNSGKVFNTVDEAYDWANAEVSDPNSQWYNKGFMVDVIIYSDGSQKHTV
                     DFY"
BASE COUNT          414 a          175 c          237 g          237 t
ORIGIN      
        1 aataaaaaaa tctacaaaaa atatatcgac tgatagacat aagtttggta ctatgttttt
       61 gtaaataaat ttattcaaat cggaggcgaa aaacaatgaa aatgttgaaa gtattggcac
      121 taggaatcgt agtcggagga gttagtcttg ctgtgggaac gaatgctgaa gcagcagaaa
      181 acaaagtttg gacacctcgt tcggcggaac aaatcaaagc agaaattaaa gggaatgaat
      241 acacaattgt ctggggagat accctaagcg caatcagtca agcaacaaat attactgtcc
      301 aaaaattagc ggacatgaat aagattacaa atgtggattt aatctatgca ggaaataaat
      361 tagtatttaa tggcaatgta gcaagtgtac aaaacagcgc aggtgaaact gtggctcaaa
      421 cagtgattca agagaaagac aaagttgatc cgaatcaacc agtaggacaa ggaacgactt
      481 caaatacaca aacgacacca aatacaacga caccaacaac accagctgga gatcaaacag
      541 gaacaactgg tggtacaaca acgccaagta caccagaaaa caatggtggc actactcaaa
      601 cacctacaca accaggtaat ggtggaaata ctggaggaga aacaactcct tctaacccaa
      661 gcacaggtgg aggaacaaca acgcctgaag aaccaagcaa tcctggtgga ggcgatcaag
      721 gcggaaatgg tggcacaacg acacctgaag agccaacaat tgtagttgga gagattggta
      781 atagtggaaa ggtatttaac actgtagatg aagcctatga ttgggctaat gcagaggtta
      841 gcgatccaaa ttcgcagtgg tacaacaaag gttttatggt ggatgttatt atttacagtg
      901 acgggtcaca aaaacacact gtagatttct actaaaaata aaagaaaagt aagtggttga
      961 tgaagactag aattataagt tctagtcttt ttttgttttg aggaggataa aaatgtttcg
     1021 gtgtcgaagt ccataagaaa ttactttaga agactgaaaa ata
//
LOCUS       DAFTHM010000234         1063 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.246, whole genome shotgun sequence.
ACCESSION   DAFTHM010000234 DAFTHM010000000
VERSION     DAFTHM010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.246"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            57..413
                     /locus_tag="L7C88_002881"
     CDS             57..413
                     /locus_tag="L7C88_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBP9559649.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
     gene            403..669
                     /locus_tag="L7C88_002882"
     CDS             403..669
                     /locus_tag="L7C88_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBP9559650.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            828..>1063
                     /locus_tag="L7C88_002883"
     CDS             828..>1063
                     /locus_tag="L7C88_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HBP9559651.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLA"
BASE COUNT          441 a          134 c          205 g          283 t
ORIGIN      
        1 ttcgaatttt tatgttatat actataatat aaaatcaata tatgatataa ttgggtatgg
       61 aaaaaatatc ttttgaaaca tttaaaagac ctaatggtca tgatgaattt ttagaatggt
      121 tggaaacatt accaaaaaaa gatagtgcga agcttttacg tacaatagaa gaaacagaaa
      181 agaatgggat gctagtagct caacggttga aatgggtgaa aaaattagac actaatttgt
      241 acgaattaag aagtaaggta ggatcaaaca tccaaagagc tatctatttc catgtggtca
      301 atggaaggta tgtcattacc catggattta ctaaaaaaac ggagaaaaca ccaataagtg
      361 aacttaaaca tgcaaaagaa cttagagagg agtggttcac aaatgatgat taaaaaattg
      421 attgaagaaa agcaaaaaga caaagatttt gcagaagcat atgaccgtga aggaagaaaa
      481 ctcgaaactg cggttgctct ttatcatgca cgggaggaag caggcctaac tcaagcggag
      541 cttgcacaaa aagcacatac aactcaatct actattgctc gaattgagag aggggataac
      601 gtatctttcg ataaacttga tgatatcgct agggcattag gcaaaaagct ggtagtagaa
      661 tttgcttaaa agcgagttga aaatatacct gtaataggct cctaactaat caattagttt
      721 agtgggcctt tttgtactaa atagataaaa gttgtcctat agtgtaaaag tcaataaatt
      781 ttatacaaaa attactttaa agagacataa agagaaaggt acaataaatg aaaaccataa
      841 atctaataaa agtatttata gcatcaccag gtgatatagc agcaaagagg aatgaagtag
      901 aagaaaccat atatagatgg aatatagaaa atacagataa tacaaaagta attttgatgc
      961 caattcgatg ggaaacgaat gcgattccta cttatataaa taatagctct gggcaaagtg
     1021 ttattaataa acaaattgta gaaaatagtg atatattatt agc
//
LOCUS       DAFTHM010000235         1062 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.247, whole genome shotgun sequence.
ACCESSION   DAFTHM010000235 DAFTHM010000000
VERSION     DAFTHM010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.247"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(37..993)
                     /locus_tag="L7C88_002884"
     CDS             complement(37..993)
                     /locus_tag="L7C88_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559652.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aa
//
LOCUS       DAFTHM010000236         1000 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.248, whole genome shotgun sequence.
ACCESSION   DAFTHM010000236 DAFTHM010000000
VERSION     DAFTHM010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.248"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            9..96
                     /locus_tag="L7C88_002885"
     tRNA            9..96
                     /locus_tag="L7C88_002885"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41..43,aa:Ser,seq:cga)
     gene            430..>1000
                     /locus_tag="L7C88_002886"
     CDS             430..>1000
                     /locus_tag="L7C88_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBP9559653.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT          328 a          165 c          195 g          312 t
ORIGIN      
        1 gtacttacgg aaggttggca gagtggtaat gcaccggact cgaaatccgg cgaaccggct
       61 aataccggcg cgcaggttca aatcctgtac cttccttata tcaacgatta gaggttgtga
      121 agaagctgtc ctgcatcaag taataagaac ggccaaacaa aaatagcttt tcctattttt
      181 tcgtttgatt gggcttatta ccgcagatgc aagcttttga acaccgtttg ttcggaataa
      241 ggggctgtga caagactttt gtcacagccc cttattgttg tacttttaac ctacaatatt
      301 ttttgattcc ccctgagtac tattttttat aaatgctagt aaatcaatct tctttggcct
      361 ttttttgata aaaaaaatac tagatgtaag ataaaagtgt aaaaacgatt tgttttagga
      421 ggggaaacga tgtgtaccgc aatcacttat gcaacgaaag accattattt tggaaggaat
      481 tttgattatg agatgtctta taatgaagtg gtcactatta ctccaagaaa ttatcgtttc
      541 gattttagaa aggtaaaaaa tttagataaa cattatgcaa tgataggaat agcagctggg
      601 gtatccaact atccactcta ttatgaggct acaaatgaaa aagggttgag tatggcagga
      661 ctgaattttc ctggcaatgc tgattataaa gaattacaag aaggaaaaga taacgttgca
      721 ccatttgagt ttattccatg gatactaggg caatgctcaa ccatagacga agctaaagaa
      781 ttattggcta ctatcaatct agtcaatatc gattttagtg aaaaactacc cttgtcacct
      841 ttacactggt tattagctga taaagaaaaa tcgatagtaa ttgaaagtat gaaagatgga
      901 cttcatttat atgataatcc tgtcggtgtg ttgacaaata atccgccatt tgattatcaa
      961 ttatttaatc tgaacaatta tcgctcgcta tcaaatggaa
//
LOCUS       DAFTHM010000237          995 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.249, whole genome shotgun sequence.
ACCESSION   DAFTHM010000237 DAFTHM010000000
VERSION     DAFTHM010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.249"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..778)
                     /gene="vanY"
                     /locus_tag="L7C88_002887"
     CDS             complement(<1..778)
                     /gene="vanY"
                     /locus_tag="L7C88_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBP9559654.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEI"
BASE COUNT          290 a          209 c          135 g          361 t
ORIGIN      
        1 agatctcata tttttcccca tttacactaa cagaaatggt tttttcttct tttaggtaat
       61 ccatatattc ctcgagaacg aaattctttt ctttcataat cgcactatgt ggtaaaccaa
      121 catagcgaat atgccatggt tcatattgaa ttcctgttaa ctctgttttg tcctctggat
      181 aacgtaaaat gaacccgtat ttccaagcat tttcttctat ccactttcct tcaggggctc
      241 gttccatttt cgtcaagctt gatcctacat ctagtgataa acctgaatta tgctcactat
      301 aacctgctgg taaggcatac tcagccccca tttcttggta aagcacactt tgctcatcaa
      361 agtctcgata gccactatta ataataaaat gactaacgcc accctttaca gcatcattga
      421 ccatctctga aaatttttgt gctatttctt ttgacatata aatattacta tcaagcaacc
      481 cgtatccatt tattaattcg tcatgtttag ataaattcac gatatctgac ttcacacttt
      541 cttggcgaac aggatattta ctattgatta atagcagatt tccttgataa acctgttctt
      601 ctgtaattgt tttctcttgg gtattttcag aagtcccact attttctaaa tgttctttgg
      661 gattttgatc ataattttga aattcgactt tttcctgaga aaacagtgct tcattaacgt
      721 agtcataacc taagtatatt aagaataaca ataacaataa aaaaaacaac ttcttcattt
      781 tcagtctcct ccttaactat atagttggaa gtatgaaata tttctagaat cttcccctta
      841 aacggcacaa tctcgtttga gattgtgccg ttttgccccg taaattacag tcaattattt
      901 cgccctactg gatttactat tatcaccaat gtagatgaat tttcataagt gatacccatg
      961 ctgaatttaa cgaggctgaa ctgcctgttg acaat
//
LOCUS       DAFTHM010000238          995 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.250, whole genome shotgun sequence.
ACCESSION   DAFTHM010000238 DAFTHM010000000
VERSION     DAFTHM010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.250"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(26..913)
                     /locus_tag="L7C88_002888"
     CDS             complement(26..913)
                     /locus_tag="L7C88_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBP9559655.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
BASE COUNT          288 a          207 c          179 g          321 t
ORIGIN      
        1 taatttcttt gcctttttat ctaaatcaaa cgtttagttc ttgaccaact aataaagaat
       61 aactggacat agacatgcca tttttcgcca ttagatcatc aacagacatg ccaaattttt
      121 gtgcaatatc ccatagcgta tcacctgaca cgactgtata tgtctgacca ttatttgtat
      181 ttacatctgt tgttgaagat gatgacgttg aagtcgtcgt agtagtcgtt gttgttgtac
      241 ttgtggttgt tgtagccgaa cctgttgatg gcgtatcaaa acgggttaaa ttataagtat
      301 taatcaatga gttcaatttg gccccataat ttggatcggt agcataacga cctgtcaagt
      361 acgctgttgc atcataaaaa cttgttgtat tgcttttcca cacgccagca taatgataat
      421 cgcccgtgga aaaactggtt gaacgaagaa cattcgcatg gtcttggaag gattcccaat
      481 aagaagaata ttttcggaat ggctcattca tcgttaccca ttgtccgttt acatattctt
      541 tggttgccat ataaacgacc tgtccgttat agcttccttt cacaccgaat agattataat
      601 ttggcgcact agctaatccg gaagtgccat atgcactttc caacaacgct tgagcgatca
      661 tgactgaagc atacaagtca ttacttgcag caacttctga cgcagaccag ccgatttgat
      721 cgataaacgc ttgaggatca gcgactgttt gagatccttg ttcatctgca tgaacatgtt
      781 gcggtaccgc tgtaaccatc atcggcccaa ctaaaagact cgttccaatt aaaggagcaa
      841 tcgctttttt attgatcacc atttttcttt taggtctatg gtgccgggca ctgcgggtct
      901 tcagctcttg cattcaaatt cctcctcaaa ataaaaaaac ttaataaaaa gttctcttct
      961 taaaacaaac ttaattaatt aaattatact tttaa
//
LOCUS       DAFTHM010000239          994 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.251, whole genome shotgun sequence.
ACCESSION   DAFTHM010000239 DAFTHM010000000
VERSION     DAFTHM010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.251"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..>994)
                     /locus_tag="L7C88_002889"
     rRNA            complement(<1..>994)
                     /locus_tag="L7C88_002889"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          209 a          307 c          225 g          253 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatg
//
LOCUS       DAFTHM010000240          988 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.252, whole genome shotgun sequence.
ACCESSION   DAFTHM010000240 DAFTHM010000000
VERSION     DAFTHM010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.252"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            159..>988
                     /locus_tag="L7C88_002890"
     CDS             159..>988
                     /locus_tag="L7C88_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HBP9559656.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT          348 a          146 c          182 g          312 t
ORIGIN      
        1 tccagatgga aatgaaccca caaatcctag ttggggcata attacttaca agaatatcgt
       61 tgaagagagt gtaaaatatt ttgtgtaaat agaaaaaagg aagtcccttc tgtagaatag
      121 agttaccaca acacattcac agaaaagagg acttccatat gaacgatttt actacagaaa
      181 ttatggaaat actaatcaat aaaggtgatt tggatgattt gtttcgtcgt cacctagaat
      241 tggctattaa cgctttatta caagctgaat taacggtatt tcttgactat gaaaagtatg
      301 atagagctgg atttaattca ggtaattccc gtaatgggaa ttattcgcgc tcttttaaaa
      361 cagagtacgg tgaattgaat ttagtaatac ctagagatag gaatggagac ttttctcaac
      421 aaactttacc tgcttataaa agaaccaatg actctttaga aaccactatt attcagctag
      481 ttcaaaaagg aattactatg tccgaaatct ctgatctaat cgaaaaaatg tatggtcatt
      541 attacaaacc acaaactatt tcaaatatga gtaaaattgt gtctgaagat gtttcggcat
      601 ttaaagaaag aactttagaa gctaaatact cagtcatttt tatggatgct actcatattc
      661 ccttaaaaag acaaaccgta tcaaaagaag ctgtctatat agtaattggt atcaggttgg
      721 atggaactaa agaggttcta ggatttacta tagctccaac tgaatctgct tatgtttgga
      781 aagagattct tcaagatcta aaagaccgtg gtttagaaga ggttttgtta gtcgtaacag
      841 atggtttaag tggtattgac gatagtattc atagtgttta tccaaatgct caatttcaac
      901 aatgttgtgt ccatatatct agaaatatcg ctcataaggt tcgtgttagt gatcgacaag
      961 aaatctgtag cgatttcaaa ttagttta
//
LOCUS       DAFTHM010000241          985 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.253, whole genome shotgun sequence.
ACCESSION   DAFTHM010000241 DAFTHM010000000
VERSION     DAFTHM010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.253"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..704
                     /locus_tag="L7C88_002891"
     CDS             <1..704
                     /locus_tag="L7C88_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBP9559657.1"
                     /translation="YSVIFMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAP
                     TESAYIWKEVLQDLRKRGLEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIA
                     HKVRVRGRKEICEDFKLVYQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFY
                     NFPHAIRRTIYSTNLIEGFNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRI
                     HKGFKEIQDTLESMI"
BASE COUNT          333 a          161 c          163 g          328 t
ORIGIN      
        1 attattccgt tatatttatg gatgcgacgc atatccctgt gaagcgacag actgtttcga
       61 aggaagcagt gtatattacg attggtattc gtttggatgg aaccaaagaa gttcttgggt
      121 ttactattgc cccaactgag tctgcttata tttggaaaga agttcttcaa gatcttagaa
      181 aacgtgggtt agaagaagtt ttattagtag tgacagacgg attaagctgt attgaagaaa
      241 gtatccatag tgtgtatccg aatgcccaat ttcaacaatg ttgtgtgcat gtatctagaa
      301 atatcgctca taaagttcgt gttcgaggtc gaaaagaaat ttgtgaggat ttcaaattgg
      361 tttaccaagc gaattcaaaa gaagaggcat tggatcacat cgactttatg actaggaaat
      421 ggaaaaagca gtatccaaga gtcgtcaatt tactcttgaa tcctgcccta ttaacctttt
      481 ataatttccc tcacgccatc agacgaacaa tttattcgac gaacctgatt gaaggcttta
      541 ataagcagct aaaacgatat actcgaagaa aagaacaatt ccctaatgaa gaatctctag
      601 agagattctt catttctcaa tttaatcaat ataaccaaaa atttttaggt agaattcaca
      661 agggatttaa agaaattcag gatacattag agtcgatgat ttaactgtaa ttaacagaat
      721 ggattttcca tttacatata attcttgacg ctaccataat ctaaataacc atcatattca
      781 tctactactt atataattga gttttattaa actttttaag tttctattct atcaaatatt
      841 taaacaatct ctgcatccga aaagactacc tcgtatagtt ttactaacaa tatttttatt
      901 agcgtgttca aatcctgatt tcttgtatca attattttct gttcactttc aataagaaaa
      961 aagtctttac ttccatggat aataa
//
LOCUS       DAFTHM010000242          973 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.254, whole genome shotgun sequence.
ACCESSION   DAFTHM010000242 DAFTHM010000000
VERSION     DAFTHM010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.254"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            696..926
                     /locus_tag="L7C88_002892"
     CDS             696..926
                     /locus_tag="L7C88_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559658.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
BASE COUNT          345 a          155 c          149 g          324 t
ORIGIN      
        1 cgatgaattc attaattgtt aaaatcagtt ttaactcact ttgatttttc caaatgatac
       61 gtccatcatt ttgcttcacg ataaaaactc ctaatagtta tttagataga agcctatcac
      121 atcaactttt tagtagaaaa gtacatgttt tgtctttttt gctaatagct gaccctttga
      181 gaaacttggg ttcaaaagtt gctaaattcg gtaaatgttt tggtattttt cgtattatat
      241 ttgtcgtcaa gctgactact aaattttgcc ctattttgac gacactgata gtcaatgtcg
      301 gacaatctag gacaattttt aagggaatat gattgaaaaa tggtccaaaa cagccaaaaa
      361 tggcttaaaa ctgtgataga gaaaaaagaa aaagcccttg atatacaagg acttttcaca
      421 aatttcagat ttccaaggaa gttttccgtg tttatcttct gatttctttg atacgagcag
      481 cttttccgtg taatgcacgt aaacaaaacc actatattct attatgtatc taataccctc
      541 aaaacagcta taaatcaaca ataccgacat ataataaaca ctatgttcaa tctgagatat
      601 atcaaagata aacgtatttt tgcccccttt ttgcccctca aatatcgctt tacaacgaga
      661 acgtaagttc gtataatcgt tttgaggtga tttttatgat ggaagacttt attagaaaaa
      721 atatcagtga tgaatatgca gacttttatg agcaaagcag caaaaaagat aaattccaga
      781 tggatgtttc aattttagct atattagctt tttccgaaaa taaacaacct gtaactgcaa
      841 aaaaagaaac agtattctct gaaggcaaaa taaaaactcg atatatatta gaggtagaaa
      901 ctaattttaa aaacagatcg gagtaatggt tatgcttttt aatgagacac aattatggtt
      961 taaattcgat cct
//
LOCUS       DAFTHM010000243          954 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.255, whole genome shotgun sequence.
ACCESSION   DAFTHM010000243 DAFTHM010000000
VERSION     DAFTHM010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.255"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            322..954
                     /locus_tag="L7C88_002893"
                     /pseudo
     CDS             322..954
                     /locus_tag="L7C88_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          324 a          179 c          177 g          274 t
ORIGIN      
        1 agaaagaaat gaacaccttc aattatctaa atctcgaaaa tggttagatg taatcatcag
       61 gaaaaacaat cttaaacgaa ttactattca tggtcttaga cacacacatg ctagcttgct
      121 tttagcaagc tagtgcaaat attaaagatg tgcaagagcg tttaggccac tcttctattc
      181 aaatcattat ggatctatat attcatatta cagacaaaag aaaagaagaa accgtagcgc
      241 aattcgcaaa atataggctc tataatttat gggactgatg aatcaaaatt gattcttcag
      301 tcccattgtt attttaggta tatgattcgt acattgaaag agttgaaaaa ctatcttccg
      361 aagccgtcaa aaaggaccct gccaaaagta ttgatggtgg atgaatttcg ttcgcacgct
      421 tcaattgtgg ataaaatgag ctttatttgt gcggatggcg agactggaaa actcattgat
      481 attttgccta cacgaaaatt gtctcgatta acacactatt ttagtcgctg tgcaaatcct
      541 gaagcggtgg aatatttagt gacagatatg aacgccgcct acttccaact gacaaaacgt
      601 gtcttaccaa atgcgaaagt cgtcattgat tgttttcata tcatcaaaca tttgaatcag
      661 gcgttcaatg attttcgtgt acaagaaatg aaaagattac accagttagg gcaacgacgg
      721 gaagccgaga aagtgaaaaa gaactggcgc tttcttctaa aaaaccgtca aaaaatcaat
      781 cactatgatt acaaaacatg gcgcagtttt cgtgcaccta aatacccgct actcactgaa
      841 gcaatgatga ttgatcgatt gctggcattt tcaacgcctt taaaggacgc ctatactttt
      901 ttccatgagc tgaccgaagc ctttagagac aaggaatcag acttattttt tacc
//
LOCUS       DAFTHM010000244          942 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.256, whole genome shotgun sequence.
ACCESSION   DAFTHM010000244 DAFTHM010000000
VERSION     DAFTHM010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.256"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            47..196
                     /locus_tag="L7C88_002894"
     CDS             47..196
                     /locus_tag="L7C88_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559659.1"
                     /translation="MKVVYKSIKPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            193..639
                     /locus_tag="L7C88_002895"
     CDS             193..639
                     /locus_tag="L7C88_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559660.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGVRSDGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYEALEHENGNLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            641..778
                     /locus_tag="L7C88_002896"
     CDS             641..778
                     /locus_tag="L7C88_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBP9559661.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIINKDKSA
                     S"
BASE COUNT          333 a          156 c          196 g          257 t
ORIGIN      
        1 gcttattcat ttgttatcac ttattcaatt taagggagga aatctaatga aagtagttta
       61 caaatcaatc aagccttacg gattcgagca aatcattgtg aatgacgaag aacatttacc
      121 ggaagaatgc acagaagtcg aaccaccgat tccaaattgg aaaccgaaat tcaattactg
      181 ggagggaaat aaatgaaaaa catttggaaa tatggccgta ctggcggaga gtatgcagga
      241 aaagtattgg acgacatgct tgtatccgtt ccttacacag atcagccacc gctcgaaggg
      301 gttcgttcag atggcgaacc gctaacgatt gctgatcaga tgtttgatcc taaattgaac
      361 caatggatta ttttagcgaa cgcgttagat cacaacgatt taaacaatct caaagcgatg
      421 tacgaggctc ttgaacatga aaacggcaac ctaaaacagc taaatgccaa actcatgcta
      481 agcgatgtag cgattaaaca ggaaaatact gcattgaaag aaaaagctga cagtttagca
      541 caaatcaatt caaaaatgat gcttgcttcg ttacaaaata gcaaagacat ttcagaaatt
      601 aaagagcaac taaatccagc ttcaaaagga ggtgagtagt atgtttagtt ttagcgatgt
      661 gaaaatgatg tatgattggg gctgttttac tgacgatcaa gttcgactat tcgttccact
      721 atgcattaca gacgaagaag cagataaaat cattaataaa gataagagcg catcttaatt
      781 gatgcgtttt tatttaaggt aaaggagttg tcacatgatt aatttagggg aatggggaat
      841 gatagcagga tcaataaccg ctatcgtttc tttgatttta ttagtaatta gaccgattgc
      901 tgcatctttc tcgaaaatta ctgagactct ttcaaaagta ag
//
LOCUS       DAFTHM010000245          875 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.258, whole genome shotgun sequence.
ACCESSION   DAFTHM010000245 DAFTHM010000000
VERSION     DAFTHM010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.258"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            2..>875
                     /locus_tag="L7C88_002897"
     rRNA            2..>875
                     /locus_tag="L7C88_002897"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          265 a          174 c          260 g          176 t
ORIGIN      
        1 ataagggcgc acggtggatg ccttggcact aggagccgat gaaggacggg actaacaccg
       61 atatgctttg gggagctgta cgtaagctat gatccagaga tttccgaatg ggggaaccca
      121 acatctttaa taggatgtta cgattgtgtg aatacatagc acattcgagg tagacgcaga
      181 gaactgaaac atctaagtac ctgcaggaag agaaagaaaa ttcgattccc tgagtagcgg
      241 cgagcgaaac gggaaaagcc caaaccagca agcttgcttg ttggggttgt aggactccaa
      301 tatggtagtt ctttcagata gtcgaatgac ttggaaaagt cagtcaaaga gggtaaaaac
      361 cccgtagacg aaatgtggaa gacacctagg aggatcctga gtacggcgga acacgagaaa
      421 ttccgtcgga atccgggagg accatctccc aaggctaaat actccctagt gaccgatagt
      481 gaaccagtac cgtgagggaa aggtgaaaag caccccggaa ggggagtgaa atagaacctg
      541 aaaccgtgtg cctacaacaa gtcaaagccc gttaatgggt gatggcgtgc cttttgtaga
      601 atgaaccggc gagttacgat tgcatgcgag gttaagttga agagacggag ccgcagcgaa
      661 agcgagtctg aatagggcgt ttgagtatgt agtcgtagac ccgaaaccat gtgatctacc
      721 catgtccagg ttgaaggtgc ggtaaaacgc actggaggac cgaacccacg tacgttgaaa
      781 agtgcgggga tgaggtgtgg gtagcggaga aattccaaac gaacttggag atagctggtt
      841 ctctccgaaa tagctttagg gctagcctcg gaatt
//
LOCUS       DAFTHM010000246          802 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.260, whole genome shotgun sequence.
ACCESSION   DAFTHM010000246 DAFTHM010000000
VERSION     DAFTHM010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.260"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>802
                     /locus_tag="L7C88_002898"
     CDS             <1..>802
                     /locus_tag="L7C88_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559662.1"
                     /translation="LLDAPYYLSKVALGENLIKPESQQPVTNSNYLINTYNIKPMVKG
                     KKYTITLEGTKPATQVFRPFFTRATGDAWEVGDLQPVEGLTDVWSGTFTAAADPHPTS
                     PQVQICQVPSTSLGNCTIKWLKLEEGDTRTPNIEQYKYRGIGMRDSNNPKDYVWDLAP
                     EYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTTAKDAQTKANANAT
                     AIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALNG"
BASE COUNT          296 a          154 c          160 g          192 t
ORIGIN      
        1 ctacttgatg caccgtatta tttgagtaag gtggctttgg gtgagaatct aattaaacca
       61 gaatcacaac aaccagttac taatagtaac tatcttatta acacctataa cattaaacca
      121 atggtaaaag gtaagaagta taccatcaca cttgaaggaa ctaagccagc aacacaggtt
      181 tttagaccat ttttcacacg agcaacagga gatgcatggg aggttggtga cttacaacca
      241 gtagaagggt taactgatgt ttggtctgga acatttacag cagcagctga cccacaccct
      301 accagcccac aagttcagat ttgtcaggta ccaagcacaa gtttaggaaa ctgtacaatt
      361 aaatggttaa aactagagga aggcgacaca cgaaccccga atattgagca atataaatac
      421 cgaggaatcg gcatgcgaga ctcaaacaat ccaaaagatt acgtctggga tctagcacca
      481 gaatatgtcg aagacaatct ggccacagat attaaaattt ctgaaattac tggtaaagca
      541 aacaattata ccgatgggaa agtatcggag attaattcgc agttgactgc ttcaattaat
      601 gaagtagaca ccacagctaa ggatgctcaa acaaaagcga atgctaatgc gactgctata
      661 gatgaattag acaataagat cgatgaacgc attaatgata cagctactac cacattaaca
      721 gttacaaacg ggaataccgg atcagcaaag ctttatcgtg aaggaaaaac agtttctata
      781 tattttgtgg ctttaaacgg aa
//
LOCUS       DAFTHM010000247          799 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.261, whole genome shotgun sequence.
ACCESSION   DAFTHM010000247 DAFTHM010000000
VERSION     DAFTHM010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.261"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..672
                     /locus_tag="L7C88_002899"
     CDS             <1..672
                     /locus_tag="L7C88_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559663.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          296 a          123 c          149 g          231 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag cgttaagaa
//
LOCUS       DAFTHM010000248          798 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.262, whole genome shotgun sequence.
ACCESSION   DAFTHM010000248 DAFTHM010000000
VERSION     DAFTHM010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.262"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            157..474
                     /locus_tag="L7C88_002900"
     CDS             157..474
                     /locus_tag="L7C88_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HBP9559664.1"
                     /translation="MKSEHQIQDEIRIALSKHGCTIFRSNAGQVTTIEGRQFYGMPKG
                     FPDLCGHRNSDGKAIYIEVKNERGKLREDQKRFAEFLNGQPVLYGVARSVEEALKIVE
                     ESS"
     gene            471..632
                     /locus_tag="L7C88_002901"
     CDS             471..632
                     /locus_tag="L7C88_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBP9559665.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            635..>798
                     /locus_tag="L7C88_002902"
     CDS             635..>798
                     /locus_tag="L7C88_002902"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559666.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWAEKPKRK
                     TPRKIAIWHG"
BASE COUNT          303 a          125 c          189 g          181 t
ORIGIN      
        1 ctggagggtt ttaaaaaaat aataaagtat taaagtaaaa aataaaaagt aaattatata
       61 aaaaagaata ggtttttggg tctgaccctc caaactctcc accaaaatct tcctaaatgc
      121 tttgatacca acgattaaac agtctggagg gttacattga aatcagaaca tcaaatacaa
      181 gacgagatca gaattgcctt atcaaaacat ggttgcacga tttttcgatc caatgcggga
      241 caagtgacaa cgatcgaagg gcggcaattt tacgggatgc caaaagggtt cccagatcta
      301 tgtggacatc gtaattctga tgggaaagca atttatatag aagtaaaaaa tgaacgcggt
      361 aagttgcgtg aagatcaaaa aaggtttgct gaatttttaa acggtcaacc tgtactatac
      421 ggtgttgcac gatcagtgga agaagcattg aaaattgtgg aggaatcatc atgacaacag
      481 aagaagtgat tcaaatgcgt attcgaagcc ttcagcgtga gattgacgat ctggaacgga
      541 caaaggcagt gatggtcaat gaaacggcga ggaaggcaat cgatttgcac atagagaatt
      601 taagaaggga aatccatcga ttggaggaat gagcgtggat aagaaagcag caatgaaacg
      661 aatcatcgaa ctgacacatt ctgagaattg gcaagaagac aaagaaatag ttgcagaagt
      721 ccaaaagctc ggtaaatcaa tgtgggctga aaagcctaaa cggaaaacgc cgagaaaaat
      781 tgcaatctgg catggtga
//
LOCUS       DAFTHM010000249          768 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.263, whole genome shotgun sequence.
ACCESSION   DAFTHM010000249 DAFTHM010000000
VERSION     DAFTHM010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.263"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(109..>768)
                     /locus_tag="L7C88_002903"
     CDS             complement(109..>768)
                     /locus_tag="L7C88_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HBP9559667.1"
                     /translation="RIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQ
                     PLEAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLT
                     DVKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQY
                     QFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEA
                     A"
BASE COUNT          213 a          176 c          147 g          232 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggtttggtt
      421 atcaaattcc tttccccggt ctgtatgaaa aagcttgacg tctgttaaag aatacggtat
      481 ccgtccaaag gcttctttta ccaatgaggc atctttcttc tcaccacagg aataaccaat
      541 aatttctcga ttaaacaaat caagtattaa gcagatataa tgccactttt tccccacgcg
      601 aacataagta agatccgtaa cgatggcttc caatggctgt tcttgtgtaa aggtccgatc
      661 taatacattc gctgttttcg cttcattaca agctgttcgt tgccctttaa aatgagcgat
      721 cgtataggta gatgtcaatc cgcggcgttt catgattcga ccgattcg
//
LOCUS       DAFTHM010000250          743 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.264, whole genome shotgun sequence.
ACCESSION   DAFTHM010000250 DAFTHM010000000
VERSION     DAFTHM010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.264"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(77..508)
                     /locus_tag="L7C88_002904"
     CDS             complement(77..508)
                     /locus_tag="L7C88_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBP9559668.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          257 a           97 c           85 g          304 t
ORIGIN      
        1 aggaatgtaa agtcttatct cttttcttaa ttgtacaatt agtattatct gcactacttt
       61 ctaattaaat aaatttttag ttattaactt gattaaaatc agagataata tcatttaatt
      121 cagtttgaag ggttgtaacg attaaatgga aattttcttc atctgtttta ttatatgggg
      181 atgttttcgt tatatataac aacttttctt tttcaatttt cattaataac tctgtcgaag
      241 tctgtacttt atcttgataa ttaaatgcag acataccact ttgtataatt gtaattattg
      301 ctgaagcaat tgaaacaatc aatagtaaag acctgtgttc ggaagcctga tcaattaata
      361 ttgggatact agctgataag actattttta taatatttcc gataccaatt actctattat
      421 aaaatcgaat ttcttttttt aatctatcga ttgtagaatc aatagattcg ataaacgctt
      481 tttgatccat cattttctct ccaatcattt tattaaaatc attaacaaaa atattataat
      541 aggatttaag taagttctaa ctaatcacat ataaaaataa aaaaacattt gtattttatc
      601 aaagttttat tatacttgtc aatttgtgta catcctaaaa tataagctat ttgtttactt
      661 ctgtagaata tatactttgt tgttagataa gttgcacatg tttatagaat ctaaataata
      721 aatttttatg taccgcccct caa
//
LOCUS       DAFTHM010000251          736 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.265, whole genome shotgun sequence.
ACCESSION   DAFTHM010000251 DAFTHM010000000
VERSION     DAFTHM010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.265"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..734
                     /locus_tag="L7C88_002905"
     CDS             <1..734
                     /locus_tag="L7C88_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBP9559669.1"
                     /translation="DKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRK
                     LMSQMGLTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKI
                     YLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQ
                     YQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIR
                     WYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          318 a           94 c          122 g          202 t
ORIGIN      
        1 cagataaata tagcaagata aagcaagaaa ttacagcgat tgtaaaagaa tcaagaaact
       61 cttatggtta tcgtagagtc actttagcgt taaagatgaa aggatataca atcaatcata
      121 aaacagttag aaaattaatg tcccaaatgg gacttacctg tcaaatccga ataaagcgat
      181 ataaatctta taaaggaaca gtaggaaaaa ttgccaagaa tgtgttaaaa cgaaattttt
      241 cagtagatac acccaataaa aaatgggtga cagacgtcac tgaattcaag ataaaaggaa
      301 gaaaaatcta tctatctcct atacttgatt tatttaacgg agaaataatt agttatagta
      361 tatcaactag tccaacatat aaactgattg aagaaatgct tcaacaagca attaaaaaaa
      421 agggaactga gggttcactg attctacatt cagatcaagg atggcagtat cagatgccac
      481 aatatcaaaa aaaattaaaa gagaataaca ttattcaaag catgtctaga aaaggaaatt
      541 gcttagataa ttctgtaata gaaaattttt ttggtgtgct taaatcagag tttttttatc
      601 gagaaaaatt ccgatcaatt gagatatttc aaagtaaatt aaatgagtat attaggtggt
      661 ataataacaa aaggataaaa ctaaagttaa atggactatc tccagtagaa tatcggaaac
      721 agtccattaa atagtt
//
LOCUS       DAFTHM010000252          726 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.266, whole genome shotgun sequence.
ACCESSION   DAFTHM010000252 DAFTHM010000000
VERSION     DAFTHM010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.266"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            16..696
                     /locus_tag="L7C88_002906"
     CDS             16..696
                     /locus_tag="L7C88_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBP9559670.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPA"
BASE COUNT          250 a          125 c          147 g          204 t
ORIGIN      
        1 gcaggaggaa tgacgatgaa tcattttaaa ggaaagcaat ttcagcagga tgtgattatt
       61 gtagccgtgg gctactatct tcgttataac cttagctatc gtgaagttca agaaatctta
      121 tatgatcgtg gcattaacgt ttctcatacg acgatttatc gttgggtgca agaatatggc
      181 aaactactct atcaaatttg gaaaaagaaa aataaaaaat ccttttattc atggaaaatg
      241 gatgaaacgt acatcaaaat taaaggaaaa tggcattatt tgtatcgagc catcgatgca
      301 gatggtttaa ccttggatat ttggttacgt aaaaaacggg acacacaagc agcctatgct
      361 tttcttaagc ggttagtgaa gcagtttgat gaaccgaagg ttgtagtcac agataaagcc
      421 ccctctatta caagtgcctt taagaaacta aaagaatacg gcttttatca agggacagaa
      481 catcgtacca ttaaatacct gaataatttg attgaacaag accatcgtcc agtaaagaga
      541 cgcaataaat tctatcgaag tttacgcact gcctctacca cgattaaagg catggaagcc
      601 attcgaggat tatataagaa aacccgaaaa gaaggcactc tcttcgggtt ttcggtctgt
      661 actgaaatca aggtattatt gggaatccca gcttaaatca tagataccgt aagggatttt
      721 attctt
//
LOCUS       DAFTHM010000253          712 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.267, whole genome shotgun sequence.
ACCESSION   DAFTHM010000253 DAFTHM010000000
VERSION     DAFTHM010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.267"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..446)
                     /locus_tag="L7C88_002907"
     CDS             complement(<1..446)
                     /locus_tag="L7C88_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9559671.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT          216 a          123 c           95 g          278 t
ORIGIN      
        1 aactttctct tttcaaaaaa aatttgatat ttttttagat ttctttttag tctttgtaat
       61 actttataag ccacagaata actcacgtga tgctgtttag caaaattttc tactgagata
      121 tatttttcct gaaagaaagc caataccatt ttcatagata aagaatccgt tatataacga
      181 gataacagag ctttgctaga acattttcca ttaatttcca gacatatatc caattcactg
      241 acggttactc gcaaattttt ctctagatcg aacttttgta aatcatgttt cagcttatcg
      301 atcgtttttt tcaagagaaa tgtcgatagc gacaactctt cttgaacatt cgatattgac
      361 tctgataaat ttgagcttgc ttctaaatat ttaagtaatg aataacttct gtgatcttct
      421 ttgcttaaaa aaaactcata attcattagt catcagctct ttctacgtat attactttcc
      481 atgcattcac caactagctg gggataaaac tgatttcctg gatccgagtc actgttgtca
      541 gcgattcttg tttgtataat atacatcgtc ctgtcttttt tttaacattt tggagagcgt
      601 tttatttggc ctttctcgcg atcaaacctg ttattagaat tatatcattt actagtatgc
      661 atttttatta ataaaatggt atattttata ttgttataaa aagagcccaa cc
//
LOCUS       DAFTHM010000254          709 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.268, whole genome shotgun sequence.
ACCESSION   DAFTHM010000254 DAFTHM010000000
VERSION     DAFTHM010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..709
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.268"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            7..624
                     /locus_tag="L7C88_002908"
     CDS             7..624
                     /locus_tag="L7C88_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559672.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
BASE COUNT          266 a           90 c          132 g          221 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtca
//
LOCUS       DAFTHM010000255          703 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.269, whole genome shotgun sequence.
ACCESSION   DAFTHM010000255 DAFTHM010000000
VERSION     DAFTHM010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.269"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(83..703)
                     /locus_tag="L7C88_002909"
                     /pseudo
     CDS             complement(83..703)
                     /locus_tag="L7C88_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          173 a          146 c          131 g          253 t
ORIGIN      
        1 tcccattcaa cgcaaaaaaa taaatagtga cggtttttcc ttcacgataa agctttgctg
       61 atccggtatt cccgtttgta actgttaagg ttacgacttc atatttgttg tcgtctgatg
      121 tcaatacaga ttttcctttt gattgaatac catcttcgaa atttttcaat ccttcgatgg
      181 attgcggttc agtcaaacta accgtatcat tcaagccttt ttcagtatat tcaggcgtga
      241 tgtcccagct gtagtcgttc ggattgttgc tatctttcaa tccttcacca aagtatttaa
      301 actgactaat attcggggtt cgggtgtcgc ctttttcaat tttgagccag tcaatttggc
      361 atgcgccggc cgtttcttta ggcaactgaa aaatgcgaag gtctttaggc aaacccggtt
      421 caagtttcgt tggtgtgaat gttagagacc atacgtctgt caatccctca actggtttta
      481 gttctccaaa attaacgttc caataattat atgctacaaa ggtttgactt gcgggttttg
      541 ttcctttaag cgtgatagta tacgtttgac ctattataag ctcttcttcc gtgttacctt
      601 tatatatttc gtacgcgcta gatttaattg ggaacgtcgt acctttattt gcaatattct
      661 cacccaacga tgttttacct acccagtaag ggtcatctag taa
//
LOCUS       DAFTHM010000256          688 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.270, whole genome shotgun sequence.
ACCESSION   DAFTHM010000256 DAFTHM010000000
VERSION     DAFTHM010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.270"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            124..327
                     /locus_tag="L7C88_002910"
     CDS             124..327
                     /locus_tag="L7C88_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HBP9559673.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
     gene            327..677
                     /locus_tag="L7C88_002911"
     CDS             327..677
                     /locus_tag="L7C88_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBP9559674.1"
                     /translation="MTSINIDHTKKVIHELYNSLMTRPNQTKALLDITDVLFQVYKKI
                     DTAKYPEILVNKLVNYIYIVGFDNKIRFIDNDEKLLIELGDISKKAGINSKYKANFTD
                     KSQFYSYSETMPQR"
BASE COUNT          287 a           69 c          115 g          217 t
ORIGIN      
        1 tcaatcattg ttatataata aaatgttata taataaaatt actaatgata tttaatatta
       61 caagcaatct taagaaattc gaaaaggaaa aaatgattat gaaaaagaaa gaaaaagaaa
      121 gtattgaaac attgtgttat tctaggaata ttaggaactt gtctagctgg cattggtaca
      181 ggaatagacg ttgacgcagc tacttactat ggaaatggtc tttattgtaa caaagaaaaa
      241 tgttgggtaa attggggaca atcatggtca gaagggttaa aacgttgggg agataatctt
      301 tttggtagtt ttagtggagg acgataatga cttcaataaa cattgatcac acaaaaaaag
      361 tcatacatga attatacaat agtttaatga cacgacctaa tcagacgaaa gcattattag
      421 atattactga tgttttattt caggtatata aaaaaattga tacagcaaaa tatcctgaaa
      481 ttcttgtaaa taaattagtt aattatattt acatcgtggg ttttgataat aaaatacgct
      541 ttattgataa tgatgaaaaa ttattaatag aattagggga tatttctaaa aaagctggaa
      601 ttaatagtaa atacaaagca aactttacag ataaatcgca attttatagt tattcagaaa
      661 caatgcctca acgataaaat atagtata
//
LOCUS       DAFTHM010000257          649 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.271, whole genome shotgun sequence.
ACCESSION   DAFTHM010000257 DAFTHM010000000
VERSION     DAFTHM010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..649
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.271"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>649
                     /locus_tag="L7C88_002912"
     CDS             <1..>649
                     /locus_tag="L7C88_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9559675.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSV"
BASE COUNT          213 a          111 c          134 g          191 t
ORIGIN      
        1 aaatcaaact gtggtagacg tccgcttgtt ttacccgagg aacaatcaga atatattcaa
       61 agaaaggttg ttcaaggatg gacacccgat gtgattgttg gtcgtgcagc gtttcctatt
      121 agttgttctg ctcgtaccat ttatcgtatg ttcaaaaagg ggctatttga ttcttctgac
      181 ttaccgatga aaggcaagcg taaaccgaat ggacatcaag aaagacgtgg aaaacaaact
      241 ttccgccgct ctattcatga acgtgaaaag gattatagcc aattctcaaa tgagtttggt
      301 caccttgaag gtgacactat cgtaggtctg aaacataaaa gtgctgtaat taccttagtt
      361 gaacgattat caaaagttat catcacattg aaaccgtgtg gtagacaagc gattgatatt
      421 gaaaaaaaat taaatcaatg gtttgaatct gtaccgaaaa acctattcaa atccatcact
      481 tttgattgtg gaaaggaatt ttcaaattgg aaacagatca gtaatgtcaa tgatattgcc
      541 atttatttcg ctgatccagg aacgccgtct caaagaggcc taaacgagaa ttctaacgga
      601 ttgttacgta gagatggttt attgaaatct atggatttca attcagtag
//
LOCUS       DAFTHM010000258          619 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.272, whole genome shotgun sequence.
ACCESSION   DAFTHM010000258 DAFTHM010000000
VERSION     DAFTHM010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.272"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            26..412
                     /locus_tag="L7C88_002913"
     CDS             26..412
                     /locus_tag="L7C88_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBP9559676.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT          230 a          102 c          122 g          165 t
ORIGIN      
        1 ataaaaataa aaaaggagat ctttcatgaa aaaaatttta gggttgatcg ttatcatatt
       61 gattgctttt ataggatgga aaggttggga ctactatcag tctacttatg taggtaaaga
      121 ttattatgcg gtagtcaaag ctccaatgcc tgcagaaact gatatcaaag cagataatgg
      181 ggaagtaatt ggaagaggtt ttaaatacaa cgtagatgct tatgctgaaa acggtgaaaa
      241 aagacagtta gatttcgatg tcattacttc tggtgactct gccaatggtt ctgcttaccc
      301 cgaaggaacg atcttgcagt tgaaagcaag cgaaaagcgg atcatagaga aaaaagtaat
      361 taccagcgat aaggtaccct catctgtaaa agaaaaatta ggcctatctt aagctaagaa
      421 tatatcgcaa aaaagcactc gaagtgagtg cttttttgct tactgattct agaaaacaaa
      481 aaaacagaat taaccttcga agtcagcctc actgttctta aagtcctaaa acaaactaaa
      541 gagcaaggca atcaatcgat ttctatacaa acaagggact gtgacaaacg tcttgtcaca
      601 gccccttatt ctgaataaa
//
LOCUS       DAFTHM010000259          609 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.273, whole genome shotgun sequence.
ACCESSION   DAFTHM010000259 DAFTHM010000000
VERSION     DAFTHM010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.273"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..574
                     /locus_tag="L7C88_002914"
     CDS             <1..574
                     /locus_tag="L7C88_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBP9559677.1"
                     /translation="AQGVNAISRLAIALSEVFDFGPINFLGKLVQENATGEAVVGKTE
                     DEQSGELTMNFASLEITPEQTKIGVDMRIPVTFKKDDLVAKLTKTAEKYGLTYEEFDF
                     LDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSGGATFARTMNQCVAFGAMFPDTPDF
                     MHQANERWELSSMYKAMEIYAEAVYRLCAK"
BASE COUNT          205 a           99 c          137 g          168 t
ORIGIN      
        1 agcacaagga gtgaatgcta tttctcgtct ggcaattgct ctttcagaag tatttgattt
       61 tggcccaatc aatttcttag gaaaattagt tcaagaaaat gcaactggtg aagctgtcgt
      121 gggcaaaaca gaagatgaac aatccggcga gctaacgatg aactttgcaa gtttggaaat
      181 cacaccagaa caaacaaaaa tcggtgtaga tatgagaatc cctgttacat tcaagaaaga
      241 tgatttagta gctaaattaa ctaaaacagc agaaaaatat gggttgactt atgaagaatt
      301 tgacttcctt gattcattat acgtgccact agacagtgag ttagtgaaaa atctattggg
      361 gacatatcgc gatattactg gagacatgac tgaaccgttt gtatcaggcg gcgctacttt
      421 tgctcgtacg atgaaccagt gtgtggcatt cggtgcgatg ttccctgata ctcctgactt
      481 tatgcaccag gcgaatgaac gatgggaatt aagtagtatg tataaagcaa tggaaattta
      541 tgcagaagct gtgtatcgtt tatgtgctaa ataaaaataa acatacaaaa agggcggata
      601 ttcaaatgg
//
LOCUS       DAFTHM010000260          605 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.274, whole genome shotgun sequence.
ACCESSION   DAFTHM010000260 DAFTHM010000000
VERSION     DAFTHM010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.274"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..>605)
                     /locus_tag="L7C88_002915"
     CDS             complement(<1..>605)
                     /locus_tag="L7C88_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBP9559678.1"
                     /translation="PIKDNEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQK
                     HDYPRINRNNTTAFKIFRAIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTEL
                     IQMYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTL
                     QTSKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSD"
BASE COUNT          198 a           86 c           74 g          247 t
ORIGIN      
        1 aatccgattt aacttttctt acaaataatt tttcactttc ttttatttga tctatatccc
       61 tttcatcaaa ccatttgttc atggaaggat caataatatg aatatttgct aatttcgaag
      121 tttgtaaagt agtttcttca atatttttca attcaagtgg taaatctggt cctccaataa
      181 catttttatt tttgaacgag gaattaaaaa aaagtgtatg aaaaaatttt tcatctgggg
      241 caaacatacc tattttaaaa ttcaggtagt cttgttgatt ttgttcatac atttgtatta
      301 attctgttag gcattctttc gacaaagccc accattgaga accatgatac aaatcaaatt
      361 tatggtgtct aatttttggg ggaagtttaa tcatcctcag acaacgatta attatagctc
      421 taaaaatttt aaatgcagtt gtgttattcc tattaattct aggataatca tgtttttgat
      481 atacatctat atgtttataa taaaattctt tatgtttaat ttgatctaga tctattccac
      541 gaataaactc cactgaacta ttctttttaa aataattata aatatactca ttatctttga
      601 ttgga
//
LOCUS       DAFTHM010000261          588 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.275, whole genome shotgun sequence.
ACCESSION   DAFTHM010000261 DAFTHM010000000
VERSION     DAFTHM010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.275"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(65..150)
                     /locus_tag="L7C88_002916"
     tRNA            complement(65..150)
                     /locus_tag="L7C88_002916"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Leu,seq:taa)
     gene            complement(167..238)
                     /locus_tag="L7C88_002917"
     tRNA            complement(167..238)
                     /locus_tag="L7C88_002917"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Gly,seq:gcc)
     gene            complement(250..322)
                     /locus_tag="L7C88_002918"
     tRNA            complement(250..322)
                     /locus_tag="L7C88_002918"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Thr,seq:tgt)
     gene            complement(340..421)
                     /locus_tag="L7C88_002919"
     tRNA            complement(340..421)
                     /locus_tag="L7C88_002919"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(385..387),aa:Leu,seq:tag)
     gene            complement(429..501)
                     /locus_tag="L7C88_002920"
     tRNA            complement(429..501)
                     /locus_tag="L7C88_002920"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(466..468),aa:Lys,seq:ttt)
     gene            complement(505..577)
                     /locus_tag="L7C88_002921"
     tRNA            complement(505..577)
                     /locus_tag="L7C88_002921"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(542..544),aa:Val,seq:tac)
BASE COUNT          149 a          169 c          138 g          132 t
ORIGIN      
        1 cccctaacct tttgatccgt agtcaaacac tctatccagt tgagctatgg gcgcatattt
       61 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
      121 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      181 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      241 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      301 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      361 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      421 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      481 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      541 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAFTHM010000262          560 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.276, whole genome shotgun sequence.
ACCESSION   DAFTHM010000262 DAFTHM010000000
VERSION     DAFTHM010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.276"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT          187 a           88 c           87 g          198 t
ORIGIN      
        1 gaagagtatt atacaagcta aagcttttct tcattgccac tcaaatgagt ggctttttta
       61 tgtatccttt tatggattaa tgaaaggatg tttcacatag ttatacttct gtatatttga
      121 aaagttttac tttgattttt aaatagaaag acatttgggt taaattgtga gataataata
      181 aagaagagtt taaagcgcac cccaaaccac ttccccataa gtgtgttacg ctttaaactc
      241 ttttatattt gaagccatta aaaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttacaattg gagtggtagt taattagtga cttatttttg attttatagc actgatacta
      361 taaaatatag atatcatcat attacacaat cttaatacta acttaaaaaa tatctccttt
      421 cacaagtatg gtgataaaat tcgttccggg ctaccttttt aggtagccta ctttaatctt
      481 tatacctttc tggatcaacg aaagtatact ttatatagtc ataacgccga tgatcgctac
      541 gtgcgtccgg cacgtcagtc
//
LOCUS       DAFTHM010000263          529 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.277, whole genome shotgun sequence.
ACCESSION   DAFTHM010000263 DAFTHM010000000
VERSION     DAFTHM010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.277"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(107..>529)
                     /locus_tag="L7C88_002922"
     CDS             complement(107..>529)
                     /locus_tag="L7C88_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBP9559679.1"
                     /translation="IDAPNGTPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKAT
                     FTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYY
                     RTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          166 a          105 c           83 g          175 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttccattggg agcgtcaat
//
LOCUS       DAFTHM010000264          526 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.278, whole genome shotgun sequence.
ACCESSION   DAFTHM010000264 DAFTHM010000000
VERSION     DAFTHM010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.278"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(6..359)
                     /gene="tnpB"
                     /locus_tag="L7C88_002923"
     CDS             complement(6..359)
                     /gene="tnpB"
                     /locus_tag="L7C88_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBP9559680.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(349..>526)
                     /locus_tag="L7C88_002924"
     CDS             complement(349..>526)
                     /locus_tag="L7C88_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559681.1"
                     /translation="IVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIYNGINNY
                     ILQAILKELLSNAL"
BASE COUNT          153 a          116 c           90 g          167 t
ORIGIN      
        1 ccagcttaaa aaactccttt ttttcctggc aaaatagctc gaggttgatc gatacttaat
       61 ccttctaaca accatcgaac ctgttggttc gttaaggttc gaacttcgtc tttcgtccga
      121 ggccatttta acttgccgtt ttctatccgc ttataacaga gaagaaaacc atcaccgtcc
      181 caatagagaa gtttgaaacg gtcttgacgg ttcccgcaaa ataaaaaaac ggcatcttcg
      241 taaagctcga gttgatactc ttgttgaata agactggcaa gaccatcaat tccttttcgc
      301 aaatctgttt ttccgcacac aatataaata tgtttggttt gaagtaaatc ataaagcatt
      361 ggacaacagt tctttcaaaa tagcttgaag aatataattg ttaataccgt tatagatcaa
      421 aacttcagaa ccattctctc ttttgatgcg catcgctaac ttggcagccg cgggtttacc
      481 tttttctggt gcactctttt cgtttcctaa ttggacagga acaatc
//
LOCUS       DAFTHM010000265          521 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.279, whole genome shotgun sequence.
ACCESSION   DAFTHM010000265 DAFTHM010000000
VERSION     DAFTHM010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.279"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            61..>521
                     /locus_tag="L7C88_002925"
     CDS             61..>521
                     /locus_tag="L7C88_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBP9559682.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYS"
BASE COUNT          195 a           72 c          105 g          149 t
ORIGIN      
        1 aaaaataaat atgttataat agtatcaaat gaatattgct aaaagaaaag aggtaggaac
       61 gtggtagcga agaaatatgt aatcggtaat tttaaaggtg gcgtaggtaa aagtacgtgc
      121 gcgcaaatgt tagggtttga atcagcagtt aatgaaggaa aaagaacctt gataattgac
      181 ttggatatgc aaggaaatac ttctgatgtg atgaacttaa cgcatatgaa cttcactaac
      241 gaagaaggag gcggagaagg tgaaccgatt gtttacgaaa atactgtgac tgacgtgttg
      301 ataaacaatc ttccacctaa agaggctgtc tataaagtaa tcaataacct ctatatactt
      361 ccagcagaca tgtcctttga aatgtatgat gattggatca aagaccaata taatgattca
      421 ttatcccaat tcaaatatat gaaagaaaag ctagaaccat tatttgatga gtttgacgtc
      481 atctatttag atgtcccacc ttctatttct gtatatagta a
//
LOCUS       DAFTHM010000266          509 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.280, whole genome shotgun sequence.
ACCESSION   DAFTHM010000266 DAFTHM010000000
VERSION     DAFTHM010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.280"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..132)
                     /locus_tag="L7C88_002926"
     CDS             complement(<1..132)
                     /locus_tag="L7C88_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBP9559683.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          183 a           93 c           91 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactatta
//
LOCUS       DAFTHM010000267          506 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.281, whole genome shotgun sequence.
ACCESSION   DAFTHM010000267 DAFTHM010000000
VERSION     DAFTHM010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.281"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(28..426)
                     /gene="spxA"
                     /locus_tag="L7C88_002927"
     CDS             complement(28..426)
                     /gene="spxA"
                     /locus_tag="L7C88_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBP9559684.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          144 a          103 c           86 g          173 t
ORIGIN      
        1 gtcttttcca agtttcgtat tatccttcta taatccagcc atcaattgtg cttgacgtaa
       61 ttctaattgt cgtacatcgc gcggtaggaa ccgacgaatt tcatcttcat taaaaccaac
      121 ttgcagacgt ttatcatcaa tcatgattgg acggcgaagc aatccaggat tgttttgcac
      181 aagttccaat aattcttgta acggcagatc atctaaatcc atgttcagtt tttggaatac
      241 tttggaacgt gtcgagatga tttcttctgt tccgtcttct gtcatttgta aaatcgcttt
      301 taattcagaa ctgttcaatg gttctgaaaa aatattacgt tcaacaaatg gaatctgatg
      361 ttcttgcaac cacgcacgag cctttctgca ggaagtacaa cttggggaag tatataatgt
      421 taacaacgtg caccactcct tttcgtgata agaatcactt ttttgtaaca gaagatcata
      481 ataatctccc atctgtttct attata
//
LOCUS       DAFTHM010000268          495 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.282, whole genome shotgun sequence.
ACCESSION   DAFTHM010000268 DAFTHM010000000
VERSION     DAFTHM010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.282"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            99..293
                     /locus_tag="L7C88_002928"
     CDS             99..293
                     /locus_tag="L7C88_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559685.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          207 a           65 c           83 g          140 t
ORIGIN      
        1 tgattctttt tatttatcat aaagatatag atacataatc attttcactt acatatattt
       61 gaatattaac taaaaacagc aagaaagaag aggatcaaat gtattatgta gaagtaaaaa
      121 caaaaggcgt caaaaacaaa caatatgtga aaggtatcag taacgaatat cctttacttg
      181 gttcatggaa agaagctgct cctttttcca aaccatgtgc cataaaaata aagaacgagc
      241 tagaaaaaga actgacttgt ggtaaagctg ttgtagatat catcgaaaag taaatccaat
      301 gtatagaaag gaagatcaca catgaaaagc gacgtacaaa ttgctaagat tatagaatta
      361 gaagaagaag acgcagtgtt gacaattgaa aaaaaataaa tgtttgtata ccatatgatt
      421 atttcaatat gtatcctgga attggagatc tcgtagagct atatcaagat gaatcaaata
      481 tacttgtcat tcatc
//
LOCUS       DAFTHM010000269          483 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.283, whole genome shotgun sequence.
ACCESSION   DAFTHM010000269 DAFTHM010000000
VERSION     DAFTHM010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.283"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>483
                     /locus_tag="L7C88_002929"
     CDS             <1..>483
                     /locus_tag="L7C88_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559686.1"
                     /translation="DLQERGLKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVFRN
                     ISHKVRVNNRKEVCDDFKMVYQASSKEVALEARGAFAKKWKTSYPKVVESILSNDHLL
                     TFYDFPLAIRKSIYSTNLIESFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFL
                     G"
BASE COUNT          144 a           95 c          102 g          142 t
ORIGIN      
        1 gaccttcaag agcgcggttt gaaaaatgtc ctcctgttca tcacggatgg cttaaagggg
       61 atggtaggag cgattagtcg gttctatccc aaagctcgtt ttcaacattg ttgtgtacac
      121 gtttttcgta atatcagtca caaagtgcgt gtcaataatc gtaaggaagt ctgtgatgat
      181 tttaaaatgg tgtatcaagc ctcatctaaa gaggtggcgt tagaagcacg tggtgctttt
      241 gcgaaaaaat ggaaaaccag ctatccaaaa gtggttgaat cgattctttc gaacgatcac
      301 ttgctcactt tctatgattt ccccttggcc atacgcaaga gtatttattc tacgaacttg
      361 attgaatcct ttaataagca aatcaagaaa tacagccacc gcaaggaaca gttccaaaac
      421 gaagagtcga tggaacgttt cttagtctcg tcttttgata cttacaacca aaaattccta
      481 ggt
//
LOCUS       DAFTHM010000270          481 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.284, whole genome shotgun sequence.
ACCESSION   DAFTHM010000270 DAFTHM010000000
VERSION     DAFTHM010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.284"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            58..>481
                     /locus_tag="L7C88_002930"
     CDS             58..>481
                     /locus_tag="L7C88_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBP9559687.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT          153 a           87 c           87 g          154 t
ORIGIN      
        1 ttatgttacg attatcttga atttgtatat tacttaacaa aagataatgg agtgtgaatg
       61 atggagacca taacgtattc ccctttgaac ttatttacga attttcaaga agctgcagct
      121 aacttttccg agaccccgat tatctttgat gagccacttt cagctttccc agaattagga
      181 cttgaaacaa cttacaaaaa atgctgcgaa agtgtgttga aacgggctta tcaattggct
      241 catcttggag tgaaatccgg agacaaagtt attatttata agagttccgc ttttgacaca
      301 taccttctag ctgtttctgt gtcttacctt ggtgcagtgc ctgtcatgac ttcttatcat
      361 ctaccaacaa caacaatgga agtatttatc gatcgtttag aagacccttt cattttattt
      421 gatgatgaga caaaaaagcg agtgagagaa atttcaaatg gaacaaaatc aaaacagatt
      481 c
//
LOCUS       DAFTHM010000271          480 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.285, whole genome shotgun sequence.
ACCESSION   DAFTHM010000271 DAFTHM010000000
VERSION     DAFTHM010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.285"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(57..254)
                     /locus_tag="L7C88_002931"
     CDS             complement(57..254)
                     /locus_tag="L7C88_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBP9559688.1"
                     /translation="MNNGTVKWFNSDKGFGFITGEDGNDVFAHFSAIQGEGFKSLDEG
                     QAVTYDIEEGQRGPQAVNIVK"
BASE COUNT          156 a           89 c           67 g          168 t
ORIGIN      
        1 ttttctaccg acataaacaa aaaaaccacc tcatatgagg cggttaacgt tcaacattat
       61 tttacgatat ttactgcttg aggaccacgt tgtccttctt caatatcata agtaactgct
      121 tggccttcat ctaaagactt aaagccttct ccttggattg ctgagaaatg agcgaatacg
      181 tcatttccat cttcaccagt gatgaaacca aaacctttat ctgagttaaa ccattttact
      241 gtaccgttat tcatatatat ttcctcctga tacgtatata atacgtgttt tattgcaatt
      301 aatattactt ggtaaaagga gtttttatag tgtgaatata tcgctcagat tacgtttcaa
      361 attagattac ttatttacta taacacggat gtaatgctaa cacaaggata atcactcgat
      421 atacggttta aatattatta tttgtcaaat taagcgagac aaaactttcc atttacgtaa
//
LOCUS       DAFTHM010000272          466 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.286, whole genome shotgun sequence.
ACCESSION   DAFTHM010000272 DAFTHM010000000
VERSION     DAFTHM010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.286"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            112..>466
                     /locus_tag="L7C88_002932"
     CDS             112..>466
                     /locus_tag="L7C88_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559689.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAVLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGMDRLQLT"
BASE COUNT          154 a           98 c           97 g          117 t
ORIGIN      
        1 aaaatgcaat acttttcgag agtgtaaaat attttgtgta aatagaaaaa aggaagtccc
       61 ttctgtagaa tagagttacc acaacacatt cacagaaaag aggacttcca tatgaacgat
      121 tttactacag aaattctaaa gactctagcg aacaaaggcg atttgaatga attattccgt
      181 gtccatttgg aaaaagctgt caatacgctt ctcaaaacgg agttaacggc tgtcctcgat
      241 tacgaaaagt acgatcgcat tggttttaac acgggtaatt ctcgtaacgg ctcctatgac
      301 cgtacggtca agaccgagta cggggaactt catctccaga ttccgcgcga ccgcaacggc
      361 gagttcaagc aacagactgt tcctgcttat agacggacga atgatacctt agaggagacc
      421 gtcattcacc tcttccgaaa aggtatggat aggctacaat taacta
//
LOCUS       DAFTHM010000273          462 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.287, whole genome shotgun sequence.
ACCESSION   DAFTHM010000273 DAFTHM010000000
VERSION     DAFTHM010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.287"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            143..400
                     /locus_tag="L7C88_002933"
     CDS             143..400
                     /locus_tag="L7C88_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559690.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
BASE COUNT          199 a           60 c           65 g          138 t
ORIGIN      
        1 ttttctgtcc acgttcattt tactccaaag ttttcctcat ttcaaaagaa aatcacagaa
       61 tacacgaaga agcgtttcta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt attactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tt
//
LOCUS       DAFTHM010000274          460 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.288, whole genome shotgun sequence.
ACCESSION   DAFTHM010000274 DAFTHM010000000
VERSION     DAFTHM010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.288"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(20..91)
                     /locus_tag="L7C88_002934"
     tRNA            complement(20..91)
                     /locus_tag="L7C88_002934"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="L7C88_002935"
     tRNA            complement(113..200)
                     /locus_tag="L7C88_002935"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="L7C88_002936"
     tRNA            complement(225..298)
                     /locus_tag="L7C88_002936"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="L7C88_002937"
     tRNA            complement(312..382)
                     /locus_tag="L7C88_002937"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="L7C88_002938"
     tRNA            complement(384..459)
                     /locus_tag="L7C88_002938"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DAFTHM010000275          456 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.289, whole genome shotgun sequence.
ACCESSION   DAFTHM010000275 DAFTHM010000000
VERSION     DAFTHM010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.289"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..273
                     /locus_tag="L7C88_002939"
     CDS             <1..273
                     /locus_tag="L7C88_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBP9559691.1"
                     /translation="PKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFC
                     DVNKHSNYEIGQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
BASE COUNT          153 a           58 c          115 g          130 t
ORIGIN      
        1 ccgaagcatg gcaataaggc agaagacgcg atcattcaga tgatggatat agaagcggag
       61 agagatgcga ttttagcggc tttgatggct cttagtctga ttagccgtca gatactctac
      121 tacagtttct gtgacgtaaa caagcactct aattatgaaa tagggcaatt gatacgagga
      181 tacggagaga agaatgtaga gaagctgaaa tccatcgcat tgatcgaatt tgctgaagca
      241 tacaaaaaag gcgtgttagt tcagtatcgt taattttgta gggtttttgt agggatagtg
      301 tagggttttt gagcggttta acgtgatatt atgatagtgt cgaaagatta gtgataggtc
      361 taagacaaaa taataataaa aggaacatcg ttttattatt gtttcacaat taagcttcga
      421 tagacagcag cggaaatatt aagaataagg atgtga
//
LOCUS       DAFTHM010000276          455 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.290, whole genome shotgun sequence.
ACCESSION   DAFTHM010000276 DAFTHM010000000
VERSION     DAFTHM010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.290"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..280)
                     /locus_tag="L7C88_002940"
     CDS             complement(<1..280)
                     /locus_tag="L7C88_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HBP9559692.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTH"
BASE COUNT          155 a           74 c           54 g          172 t
ORIGIN      
        1 aatgagtata gtatgaatta gtaatttggt tttcatctaa gtttagcttt gatttactaa
       61 aattgatatc tcgatacatg ttcaatacat ctaatacaaa tcgagaatct tctttcggaa
      121 atggctcaga aagatcactc caaatttcat catcataatg atactcgtaa ccttctctca
      181 atatttcgat ttttctttca taataagatc tgttttggtc ctcaaattta gccaataact
      241 caaattgatt tactagtgac aatctctgaa aactgtccat taaatgtttc ttcctatctt
      301 gttcattaac aaaaaattat aagcccttac aacgaatatt atatattaaa tttaattgta
      361 ggtgaacacg aattttataa atatttatgg tgttaatgac aaatgatatc cgactcctct
      421 tcatacgttc tggactattt gctaatagat taaaa
//
LOCUS       DAFTHM010000277          452 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.291, whole genome shotgun sequence.
ACCESSION   DAFTHM010000277 DAFTHM010000000
VERSION     DAFTHM010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.291"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>452
                     /locus_tag="L7C88_002941"
     CDS             <1..>452
                     /locus_tag="L7C88_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559693.1"
                     /translation="GKPNLMSKLKSSDFNVGYHGSLTSDNEKLHFTSDGTGSIIMFTR
                     INTPQLASGKTYTLSAKVRFDEGTTGAIDKLRLVYRTSPGEKILLEANSTNITTDDVG
                     KEITIKGTANVNYQITNLDRFYMSISFVDRDKINGGFKLYDIKIEEGST"
BASE COUNT          165 a           68 c           92 g          127 t
ORIGIN      
        1 ggtaagccga atttaatgtc caaactaaaa tcgagcgatt ttaacgttgg ttaccacggg
       61 tcactaactt cggataacga aaagctacat tttacttctg atggtacagg aagcattatt
      121 atgtttacgc gtattaatac acctcagctt gctagtggga aaacctatac tctgagtgcg
      181 aaagttcgat ttgatgaagg aactacagga gctattgata aattacgttt ggtgtatcgt
      241 acatcaccag gagaaaagat attattggaa gcaaatagta caaatattac aacagatgat
      301 gtagggaaag aaataacaat caaaggtaca gctaacgtta attatcaaat cacaaattta
      361 gatcgatttt atatgagtat tagctttgtt gacagggata aaataaatgg cggatttaag
      421 ttgtacgaca tcaaaatcga agaaggctca ac
//
LOCUS       DAFTHM010000278          434 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.292, whole genome shotgun sequence.
ACCESSION   DAFTHM010000278 DAFTHM010000000
VERSION     DAFTHM010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.292"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT          159 a           64 c           68 g          143 t
ORIGIN      
        1 agtcaaccga tggagaatta gaaacaatct acagtaggga agaaccattt acacaaaatt
       61 attgacgctc ccaagctaaa actcctatta atcgatctac taaaaataaa taaaaaaatt
      121 cttttcaatt tttatttatg gtatgacata aataaagtaa agttattctt ctaggttaat
      181 cttattaata ctctttctca ctagtgttgc atgcaacact agtgagaaag agtattaaat
      241 atactgcaag gcaagacatt tggtaattga agaataacaa gcaaaaaaat agcagtcagg
      301 tctcttgaca aagtatagtt gctattcttt ttttaggccc tactttaatg aaatttttgt
      361 ttggagggaa cgacttcatt cctttgatta tttcagttga atttaataga gaagcctggc
      421 gtctattaag aaat
//
LOCUS       DAFTHM010000279          415 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.293, whole genome shotgun sequence.
ACCESSION   DAFTHM010000279 DAFTHM010000000
VERSION     DAFTHM010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.293"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..339)
                     /locus_tag="L7C88_002942"
     CDS             complement(<1..339)
                     /locus_tag="L7C88_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9559694.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DAFTHM010000280          405 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.294, whole genome shotgun sequence.
ACCESSION   DAFTHM010000280 DAFTHM010000000
VERSION     DAFTHM010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.294"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            21..>405
                     /locus_tag="L7C88_002943"
     CDS             21..>405
                     /locus_tag="L7C88_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559695.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHH"
BASE COUNT          150 a           71 c           69 g          115 t
ORIGIN      
        1 acagaaaaga ggacttccct atgaatgatt ttactacaga aattgtgcaa actctagtca
       61 ctaaaggcga tttaaatgaa ttattccgtt cgcacttaga aaaagcgata aacacactcc
      121 tacggactga attaacggct tttttagatt acgaaaaata tgatcgcact ggttttaatt
      181 caggtaattc gagaaacggt tcttactttc gatcaatcaa aaccgaatat ggtgaattaa
      241 cattggaaat acctagagat cgtaatggtg agtttaaaca acaaacttta ccagcctaca
      301 aaagaacaaa cgatacattg gaaaccacta ttatccattt attcgaaaaa ggtgttacga
      361 tgtctgaaat tgctgatttg atcgaaaaaa tgtacggtca tcact
//
LOCUS       DAFTHM010000281          404 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.295, whole genome shotgun sequence.
ACCESSION   DAFTHM010000281 DAFTHM010000000
VERSION     DAFTHM010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.295"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>404
                     /locus_tag="L7C88_002944"
     CDS             <1..>404
                     /locus_tag="L7C88_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559696.1"
                     /translation="PEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDK
                     SDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVV
                     VTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          166 a           60 c           92 g           86 t
ORIGIN      
        1 ccagaagata aacttccagt gttgaaagca aaagatggtt atacagatgc gaaatggcca
       61 gaggaagcaa ctcaaccaat tacagcagat gatacagaat ttgtatcaag tgcaacaaaa
      121 ctggatgata aatctgacgc tgacaaatat aatcctgaag gtcaaaaagt gactacagaa
      181 ttgaataagg aaccagacgc atttgaggga attaagaaca aagaagattt accaaaagat
      241 actaagtata cttggaaaga aaaagtagat gttagcgcag ctggaaataa aaaagggact
      301 gttgtagtga catatccaga tggatcatct gatgaagttg aagtagatgt tacagtgaca
      361 gacaatcgtt ctgacgccga taaatatgag ccaacagtag aagg
//
LOCUS       DAFTHM010000282          401 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.296, whole genome shotgun sequence.
ACCESSION   DAFTHM010000282 DAFTHM010000000
VERSION     DAFTHM010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.296"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT          112 a           98 c           76 g          115 t
ORIGIN      
        1 attataaata actcataaaa aatattttga ctttcaaaat cacttttgct accagaagtt
       61 gaggcgaagt gttttaagca tagttgtacc ctagtttgac cgttaaaaat aaataacgat
      121 cgctagagtg caactatgtt tgtttgccct accgtcagcg tcggcttggc ctctcacatc
      181 cattaccgtc gggattatct ccgttacata cccttacaaa atacgccctg taagcattgc
      241 atgaaaccac cgtgcatttg caccgtattt ccgccctagc cgttcaaatc ggtcgctacc
      301 accattcaga aacacgtgcg gtaatggaag gtttggagga agctatccag accactaacg
      361 attgtcccta tcgtcgtacg tttcactcag atcaaggttg g
//
LOCUS       DAFTHM010000283          388 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.297, whole genome shotgun sequence.
ACCESSION   DAFTHM010000283 DAFTHM010000000
VERSION     DAFTHM010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.297"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>388
                     /locus_tag="L7C88_002945"
     CDS             <1..>388
                     /locus_tag="L7C88_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBP9559697.1"
                     /translation="TPQREATLLVLLENEKEHLSAEEIFFLVKKKSPEIGLATVYRTL
                     EILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHLLCLNCGTIEEVEEDLLLEVEQVV
                     EERYHFLVKDHRLTFHGICQECYEKE"
BASE COUNT          135 a           58 c           85 g          110 t
ORIGIN      
        1 tgacaccgca aagagaagct actctgcttg tgcttttgga aaatgagaaa gagcatttat
       61 ctgcagaaga aatcttcttt ttagtgaaaa aaaagagtcc ggaaattgga cttgctactg
      121 tttatcgaac ccttgaaatc ttgacagaat tgaaaattgt cgataaagta agttttaatg
      181 atggattagc ccgttatgat ttgagaaaag aaggcgccaa acatttccat catcatttac
      241 tatgcttgaa ctgcggcacg atcgaggaag tagaagagga tcttttactt gaagtggagc
      301 aagtagtaga agaacgttat cattttttag taaaagatca tcggctaacg ttccatggaa
      361 tctgtcagga atgctatgaa aaagaaaa
//
LOCUS       DAFTHM010000284          381 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.298, whole genome shotgun sequence.
ACCESSION   DAFTHM010000284 DAFTHM010000000
VERSION     DAFTHM010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.298"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(21..94)
                     /locus_tag="L7C88_002946"
     tRNA            complement(21..94)
                     /locus_tag="L7C88_002946"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="L7C88_002947"
     tRNA            complement(108..181)
                     /locus_tag="L7C88_002947"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="L7C88_002948"
     tRNA            complement(209..281)
                     /locus_tag="L7C88_002948"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="L7C88_002949"
     tRNA            complement(301..374)
                     /locus_tag="L7C88_002949"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
BASE COUNT          103 a          108 c           90 g           80 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat t
//
LOCUS       DAFTHM010000285          367 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.299, whole genome shotgun sequence.
ACCESSION   DAFTHM010000285 DAFTHM010000000
VERSION     DAFTHM010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.299"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..>367)
                     /locus_tag="L7C88_002950"
     CDS             complement(<1..>367)
                     /locus_tag="L7C88_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HBP9559698.1"
                     /translation="SPVDNYRSGTIAEIDYFYKNSKGEVGVFFLDEPVPQVLAEEYIE
                     VKKYRDSLEDKGFYGTYSKDNIRRFLTKKVNYLIEKAQNNLESKRFDLDSISYKTPSV
                     INKKVTGTDKDFDDNLDIFD"
BASE COUNT          114 a           67 c           45 g          141 t
ORIGIN      
        1 gatcaaaaat atctaagttg tcatcaaaat ctttatcagt tccggtaact tttttgttaa
       61 ttactgaagg tgtcttgtaa gaaatagaat ctaaatcaaa gcgttttgat tctaaattat
      121 tttgtgcttt ctcaattaaa taattcactt tttttgtgag aaaccttctg atattgtctt
      181 tgctatatgt tccataaaaa cccttatctt ctaaagagtc cctgtacttc ttaacttcta
      241 tatactcttc agccaaaact tgtggaactg gttcatctaa gaaaaaaacc cctacctcgc
      301 ctttgctatt tttataaaag taatcaattt ctgctatagt tcccgatcta taattatcaa
      361 ctggaga
//
LOCUS       DAFTHM010000286          363 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.300, whole genome shotgun sequence.
ACCESSION   DAFTHM010000286 DAFTHM010000000
VERSION     DAFTHM010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.300"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            54..>363
                     /locus_tag="L7C88_002951"
     CDS             54..>363
                     /locus_tag="L7C88_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559699.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     V"
BASE COUNT          137 a           37 c           70 g          119 t
ORIGIN      
        1 tatcttatcg tagatatata ttataaattt aataagaaag cgaggtgaga atcgtgaaaa
       61 aaacgatact aagtattttt tcagtattta caatattaat tgggggctat tttcttttga
      121 atttagattc tgttaattca aacgctcaaa taaaagatca aagagtagct gaacataata
      181 ataaaaaaat gagtttgacc aaaaatatct attctatgtc agatgaagaa ttgtataaag
      241 aatttggtga tttatccggg gaacagttag aagaaagtat tccaggaatt agtgactcag
      301 ataaaattgt tgtcttgtct gctggtgggc aattaatggg agatggcaaa tccgaattag
      361 tta
//
LOCUS       DAFTHM010000287          363 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.301, whole genome shotgun sequence.
ACCESSION   DAFTHM010000287 DAFTHM010000000
VERSION     DAFTHM010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.301"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT          144 a           46 c           45 g          128 t
ORIGIN      
        1 ttttacactc tctgattgac gtcataaaaa gtagctttga attcataatc gtttatataa
       61 cgattaatag aaaacaatat agtatttagt gttcatacaa tgattctaag atcattttga
      121 attaatcagt cttatagttg atttctaaat tgtcatatat tattaaaaat ttttgccatt
      181 taaaaagaaa agcgacagtt taccaataaa tttcaactga attatctaaa agtagatcag
      241 ttagtttaga taattcagtt gaaattgacc gactcaaatt acttgtataa tacctaggaa
      301 aaaattaact agcaccacgg gtatagttat ttatatttat aacaaataaa ccagagaaat
      361 agc
//
LOCUS       DAFTHM010000288          358 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.302, whole genome shotgun sequence.
ACCESSION   DAFTHM010000288 DAFTHM010000000
VERSION     DAFTHM010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.302"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>358
                     /locus_tag="L7C88_002952"
     CDS             <1..>358
                     /locus_tag="L7C88_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559700.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQV"
BASE COUNT          143 a           66 c           55 g           94 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaa
//
LOCUS       DAFTHM010000289          348 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.303, whole genome shotgun sequence.
ACCESSION   DAFTHM010000289 DAFTHM010000000
VERSION     DAFTHM010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.303"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT          147 a           39 c           44 g          118 t
ORIGIN      
        1 tcattttcca atagaaaatt caaaggatta ctggtttttc taaaatagtt tagtttaaat
       61 acataagtat cctccgacac tgtattagtt cataatcatc taaatacaaa attttcaaat
      121 aaaaatattt caagctctat cgttgacgaa tgtaaacgat acttataaag taatagaaat
      181 tgattacatt tgtaaactta aaatggttaa tttatctcac ataaaactaa gaataaaata
      241 atgattaaaa gtggttagtt tttatacgat ttagcctatc ggtaaaaatg aattagagag
      301 tgtaaaatat tttgtgtaaa tgaaaaaatc catacaaaaa aggaagtc
//
LOCUS       DAFTHM010000290          344 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.304, whole genome shotgun sequence.
ACCESSION   DAFTHM010000290 DAFTHM010000000
VERSION     DAFTHM010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.304"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            63..>344
                     /locus_tag="L7C88_002953"
     CDS             63..>344
                     /locus_tag="L7C88_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559701.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTK"
BASE COUNT          123 a           62 c           63 g           96 t
ORIGIN      
        1 tcttgtgcgt ttcttgtggt attctgtaac aaaatcagtt cgattcaagg tggtgaaaaa
       61 ttttggaaac tacagatacg ttgcttcagt tgcttcaaga agcccataaa accaatcaag
      121 cacaacaaca aaccattcag aatcttacaa ctgaaatcca actattgaat gaaaaggtca
      181 attatttaac caacaaatta tttggacgct ctaaagagac tctctttgag gaaacgaatg
      241 ggcaattgaa tctttttagt gatgaagaaa tttctgtaag tgttccagaa gcagctgcca
      301 ccattattcc agtaaaagga catcaacgag ttgtaggaac gaaa
//
LOCUS       DAFTHM010000291          338 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.305, whole genome shotgun sequence.
ACCESSION   DAFTHM010000291 DAFTHM010000000
VERSION     DAFTHM010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.305"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            1..338
                     /locus_tag="L7C88_002954"
                     /pseudo
     CDS             1..338
                     /locus_tag="L7C88_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          142 a           59 c           64 g           73 t
ORIGIN      
        1 gtaaagcaat ctaaaacgag tggttcattc aaagaaaaag ataatcttac gcctgaacaa
       61 aaagaattgt tagaactacg taaaagaaac cagcaattag aaatggaaaa tgatatttta
      121 aagcaagcag cgctgatatt cggacgaaga gacaagtaat cgatgcgaat aagcatcttt
      181 accctatatc agcgatgtgc agaatattag gtctatcacg tcagtcctat tattatcaat
      241 caaaaccaaa gaaagacgaa tcagaacttg aagaagtagt cgctgaagaa tttatccgca
      301 gccgaaaggc ctacggctca agaaaaataa aaaaagcc
//
LOCUS       DAFTHM010000292          336 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.306, whole genome shotgun sequence.
ACCESSION   DAFTHM010000292 DAFTHM010000000
VERSION     DAFTHM010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.306"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>336
                     /locus_tag="L7C88_002955"
     CDS             <1..>336
                     /locus_tag="L7C88_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBP9559702.1"
                     /translation="TLEDILKKYEILANQKKITVNNYILDENVYIGKTALKIILSNLI
                     SNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIFDVKFDLNKENSNGLGLYI
                     VSNILNNYN"
BASE COUNT          147 a           19 c           53 g          117 t
ORIGIN      
        1 tacattagaa gacatattaa aaaagtatga aatattagca aatcaaaaga aaataactgt
       61 caataattat atattagacg agaatgttta tataggaaaa acagctttaa agattattct
      121 atctaatttg attagtaatg cggtaaaata tactgatgta aatggggtaa ttaatattgg
      181 gatagttaat gattggttat atatagagaa ttcatacggt aacaataaaa tttcgaatat
      241 ggataaaata tttgatgtta aatttgattt aaataaggaa aatagtaatg gattaggttt
      301 atatattgta agtaatattc tgaataatta caatat
//
LOCUS       DAFTHM010000293          323 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.307, whole genome shotgun sequence.
ACCESSION   DAFTHM010000293 DAFTHM010000000
VERSION     DAFTHM010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.307"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>323
                     /locus_tag="L7C88_002956"
     CDS             <1..>323
                     /locus_tag="L7C88_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9559703.1"
                     /translation="LYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPD
                     NYPDFNSEFGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWF
                     SRFPK"
BASE COUNT          107 a           65 c           56 g           95 t
ORIGIN      
        1 cactttatcg tttattttct aaaggaatat ttgatattga cacactaccg atgaaaggta
       61 aaagaaaacc caatggccat caggaaaaac ggggaaaaca acagtatcag cgctcaatcc
      121 atgatcgacc tgataattat cctgatttca attctgagtt tggtcacctt gaaggtgata
      181 cgatcgttgg cattcatcat aaaagtgccg tcattacttt agttgaaaga ttatctaaag
      241 tcattatcac gattaaaccc aacggccgta aggcattaga tattgaaact gcccttaatc
      301 aatggttttc tcgcttccct aaa
//
LOCUS       DAFTHM010000294          321 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.308, whole genome shotgun sequence.
ACCESSION   DAFTHM010000294 DAFTHM010000000
VERSION     DAFTHM010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.308"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(69..321)
                     /locus_tag="L7C88_002957"
                     /pseudo
     CDS             complement(69..321)
                     /locus_tag="L7C88_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DAFTHM010000295          319 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.309, whole genome shotgun sequence.
ACCESSION   DAFTHM010000295 DAFTHM010000000
VERSION     DAFTHM010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.309"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..306
                     /locus_tag="L7C88_002958"
     CDS             <1..306
                     /locus_tag="L7C88_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559704.1"
                     /translation="IRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLI
                     EGFNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT          127 a           47 c           45 g          100 t
ORIGIN      
        1 ataaggttta tgatagataa atggaaaaag cagtatccac gagtggttaa attgctcatg
       61 aatcctgcta tattaacctt ttataatttc cctccgtcaa tcagaagaac tatttattca
      121 actaatttga ttgaaggttt taacaaacaa ttaaagaaat ataccaaaag aaaagagcaa
      181 tttcctaatg aagaatctct ggagagattt ctagtatctc aattcaacaa ctataatcaa
      241 aagtttctat gccgagttca taaaggtttt aaagaaatac atgatacatt agaatcaatg
      301 ttttaacttg atcaacaga
//
LOCUS       DAFTHM010000296          311 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.310, whole genome shotgun sequence.
ACCESSION   DAFTHM010000296 DAFTHM010000000
VERSION     DAFTHM010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.310"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="L7C88_002959"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="L7C88_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBP9559705.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           98 a           46 c           50 g          117 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc a
//
LOCUS       DAFTHM010000297          296 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.311, whole genome shotgun sequence.
ACCESSION   DAFTHM010000297 DAFTHM010000000
VERSION     DAFTHM010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.311"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT           97 a           42 c           46 g          111 t
ORIGIN      
        1 acggttgtgt aaaaatatca ttttagagca tgaaaaaaag agtggatttc tccactccaa
       61 aaaagtctaa cttttggggg tcactacatt tttgatcctt tttatttgat taattatatc
      121 cagctggata ataattttgg gggcaacatt tctatcttac tattatcttc ctaaagtagt
      181 agactttctt attgggaaaa attacaacaa aaaggagtgg cttagttgac aactcctttt
      241 tgtttacaaa tcaattggat atctataaat tgtattttct aacgaatttt atagac
//
LOCUS       DAFTHM010000298          295 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.312, whole genome shotgun sequence.
ACCESSION   DAFTHM010000298 DAFTHM010000000
VERSION     DAFTHM010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.312"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT          114 a           39 c           25 g          117 t
ORIGIN      
        1 tattggattt tattaacaat tcaaattctt ttgttaatta gtttaaatac attcaatagc
       61 attcattagt tatatgtatt aaatctaaaa caaccatttc atgaaaaata acatcctttc
      121 tatcactatt agattcatat ctcttttttt gagttaaacc agaaataact ttttcaaaat
      181 aaaattttaa cgccaatcca tgagtcaatt caaaaaaaga aaaaagattc tttgttttct
      241 cagaagttca attctttatt atttatgatt tgtcaaatta agctagaata aaatg
//
LOCUS       DAFTHM010000299          285 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.313, whole genome shotgun sequence.
ACCESSION   DAFTHM010000299 DAFTHM010000000
VERSION     DAFTHM010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.313"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            1..285
                     /locus_tag="L7C88_002960"
                     /pseudo
     CDS             1..285
                     /locus_tag="L7C88_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          111 a           58 c           54 g           62 t
ORIGIN      
        1 tcaaacaaca aatcgtcgat ctctatctcg ctggtaagcc tcgcgcagaa attattcgag
       61 agtatgagct tacgccttct tctttcgata aatggatgaa gcaagcacaa tcaacgggct
      121 cattcaaaga aagagacaac ttaacaccag aacaagcaga attgatcgca ctaagaaaga
      181 aaaataagca actcgaaatg gagaatgata ttttaaagca agcggcgctg atattcggac
      241 gaaaagacaa gtaattgatg ccaacaagca taaatattcc atatc
//
LOCUS       DAFTHM010000300          282 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.314, whole genome shotgun sequence.
ACCESSION   DAFTHM010000300 DAFTHM010000000
VERSION     DAFTHM010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.314"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>282
                     /locus_tag="L7C88_002961"
     CDS             <1..>282
                     /locus_tag="L7C88_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HBP9559706.1"
                     /translation="QSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSRPKGK
                     KGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNC"
BASE COUNT           84 a           52 c           56 g           90 t
ORIGIN      
        1 aacaatcgaa gagacttttt cctgaaatca attgtgttgt cgctgatgct gggtataaga
       61 cacctaagtt tgttcacttt ttgactcatt tgaaccttcg accttgtttg ccttattcaa
      121 ggcccaaagg gaaaaagggg ctattatcaa aaaatgagtt tctctatgac gagtattttg
      181 attgttatat ttgtccgcaa gatcaaatgc tcgctttttc aacggttact cgagaagggt
      241 accgagaata caaatccaat ccaaaagaat gtgtgaactg tc
//
LOCUS       DAFTHM010000301          279 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.315, whole genome shotgun sequence.
ACCESSION   DAFTHM010000301 DAFTHM010000000
VERSION     DAFTHM010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.315"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..>279)
                     /locus_tag="L7C88_002962"
     CDS             complement(<1..>279)
                     /locus_tag="L7C88_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9559707.1"
                     /translation="HKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHL
                     FKSMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRR"
BASE COUNT           77 a           57 c           55 g           90 t
ORIGIN      
        1 cgtctaagca agccgtttga gtgctcattt agccctcttt gcgaaggtgt tcctggatct
       61 gcgaaaaaga tggcaatatc gttcgagtta cttatagatc gccagttgga aaattctttt
      121 ccacaatcaa atgtcatgga tttaaacaag tgtttaggca tggatttgaa ccaatcattt
      181 aacctgtttt cgatatcttc ggctcgtctg cctgtcggtt tcaaagtaat aataaccttg
      241 gataaacact caaccaatgt aataacagcg ctcttgtgt
//
LOCUS       DAFTHM010000302          275 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.316, whole genome shotgun sequence.
ACCESSION   DAFTHM010000302 DAFTHM010000000
VERSION     DAFTHM010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.316"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT          127 a           34 c           41 g           73 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacat
//
LOCUS       DAFTHM010000303          270 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.317, whole genome shotgun sequence.
ACCESSION   DAFTHM010000303 DAFTHM010000000
VERSION     DAFTHM010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.317"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>270
                     /locus_tag="L7C88_002963"
     CDS             <1..>270
                     /locus_tag="L7C88_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBP9559708.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGW"
BASE COUNT           83 a           56 c           53 g           78 t
ORIGIN      
        1 atccatcgtc gtttctacac cagtatctgc catcagaaaa tcacgacgga tacaactgaa
       61 tttaaatacc atgaagtgga tgccaaaggc attatccgtc aaaagaaatt gtatctagat
      121 ccttttatgg atatgttcaa tagtgagatt ttatcctatc gtatctctga aaagcccaat
      181 gcattagcgg taatggaagg tttggaggaa gctatccaga ccactaacga ttgtccctat
      241 cgtcgtacgt ttcactcaga tcaaggttgg
//
LOCUS       DAFTHM010000304          269 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.318, whole genome shotgun sequence.
ACCESSION   DAFTHM010000304 DAFTHM010000000
VERSION     DAFTHM010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.318"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT          114 a           44 c           27 g           84 t
ORIGIN      
        1 aattataaat agatggaatt aaaaaatttt ctctgttaat gattatagtt aagataaaac
       61 taatcattgc tccaatcagt agccaagaaa aacgcatttt aaaaaaattt ttctttataa
      121 aaacctcata caaaactata attccacccc aagcaaaagc tattttcatc gggatattag
      181 ttacattaaa agtactaggc ataaaataaa gcagacaaat gattaaattt attactcgaa
      241 acgcatctcg acttaataaa ctcttctct
//
LOCUS       DAFTHM010000305          262 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.319, whole genome shotgun sequence.
ACCESSION   DAFTHM010000305 DAFTHM010000000
VERSION     DAFTHM010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.319"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            81..>262
                     /locus_tag="L7C88_002964"
     CDS             81..>262
                     /locus_tag="L7C88_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBP9559709.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT           83 a           53 c           43 g           83 t
ORIGIN      
        1 tatgaaatat tttcacgtgt taaagtattc ctcgttgaac acaacaaata aaacttttta
       61 acgaataaag gagatttttc atgacatcac ttaaaacttt actttttgga acaactttgg
      121 ctgccggcgc tgcattcttc atgggaacga ctgctcatgc ggacgaagct tataccgttc
      181 aatcaggtga tactctatca acgatttctc aaaaatacgt tggtgataac tccttgatca
      241 atgccattgc agaatcaaat tc
//
LOCUS       DAFTHM010000306          261 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.320, whole genome shotgun sequence.
ACCESSION   DAFTHM010000306 DAFTHM010000000
VERSION     DAFTHM010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.320"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            22..>261
                     /locus_tag="L7C88_002965"
     CDS             22..>261
                     /locus_tag="L7C88_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9559710.1"
                     /translation="MIESYYLQHNKPVEIANRMGRAIQTIYNVVNKFKQGKTALDYWH
                     QYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDV"
BASE COUNT           98 a           45 c           49 g           69 t
ORIGIN      
        1 cttaccatag acgaactgac aatgatagaa tcatattatc ttcaacataa taagccggtt
       61 gaaatcgcta accgaatggg acgtgctata caaactattt ataatgtagt caataagttc
      121 aagcaaggca agactgctct tgattattgg caccagtata aagaaaataa gaaaaaatgt
      181 ggtagaaaag tcattcaatt acctgctcat gaagtagatt acattaaaga gaaagtcact
      241 cttggttgga cgcctgacgt c
//
LOCUS       DAFTHM010000307          256 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.321, whole genome shotgun sequence.
ACCESSION   DAFTHM010000307 DAFTHM010000000
VERSION     DAFTHM010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.321"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT           86 a           47 c           35 g           88 t
ORIGIN      
        1 gtatagcaag caaaattctt ctccacttcc agaatttttt attttcattt ttagaaaagt
       61 gaaaaaactg acaacaaaag cttgtttctt tcactctatt aatatcttta gtgaaaaagc
      121 tcgttttata tcgtattctt ccagcgaatg tacttctcat aagtccaaaa aaagctgcga
      181 aaaagaaagt acctcggtac ctactttttc gtagctgcac ataacttgag caagtattaa
      241 tcgaagatac ttttgt
//
LOCUS       DAFTHM010000308          241 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.323, whole genome shotgun sequence.
ACCESSION   DAFTHM010000308 DAFTHM010000000
VERSION     DAFTHM010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.323"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..220)
                     /locus_tag="L7C88_002966"
     CDS             complement(<1..220)
                     /locus_tag="L7C88_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9559711.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DAFTHM010000309          239 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.324, whole genome shotgun sequence.
ACCESSION   DAFTHM010000309 DAFTHM010000000
VERSION     DAFTHM010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.324"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>239
                     /locus_tag="L7C88_002967"
     CDS             <1..>239
                     /locus_tag="L7C88_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9559712.1"
                     /translation="AIIALKPEGRKAVDIENSINEWLQSVPKNLFKSITFDCGKEFSN
                     WKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT           84 a           46 c           43 g           66 t
ORIGIN      
        1 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
       61 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      121 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      181 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaaga
//
LOCUS       DAFTHM010000310          225 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.325, whole genome shotgun sequence.
ACCESSION   DAFTHM010000310 DAFTHM010000000
VERSION     DAFTHM010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.325"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..175)
                     /locus_tag="L7C88_002968"
     rRNA            complement(<1..175)
                     /locus_tag="L7C88_002968"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           50 a           60 c           49 g           66 t
ORIGIN      
        1 cctgtttcca agtgttatcc ccttctgatg ggcaggttac ccacgtgtta ctcacccgtt
       61 cgccactcct ctttttccgg tggagcaagc tccggtggaa aaagaagcgt tcgacttgca
      121 tgtattaggc acgccgccag cgttcgtcct gagccaggat caaactctca taaaaagttc
      181 gaacaatctt gcgattgtta agctcaattt gtttgctagc atatt
//
LOCUS       DAFTHM010000311          224 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.326, whole genome shotgun sequence.
ACCESSION   DAFTHM010000311 DAFTHM010000000
VERSION     DAFTHM010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.326"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT           91 a           36 c           28 g           69 t
ORIGIN      
        1 attgtgatcc acctcttttg tttattagtt taaaccatca aaccattttt aataaaatat
       61 gtaaattcct ttgctcaaaa aagtagcttc tttacgattc gacaatttca aataaagcag
      121 gtaaaaactg gctgtcagaa aatagccaaa ctgaagcaaa aaataatgtt aaaattaatt
      181 aatgaacgaa aaaaatccct cacctaatat tacggtgagg aatt
//
LOCUS       DAFTHM010000312          220 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.327, whole genome shotgun sequence.
ACCESSION   DAFTHM010000312 DAFTHM010000000
VERSION     DAFTHM010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.327"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..188)
                     /locus_tag="L7C88_002969"
     CDS             complement(<1..188)
                     /locus_tag="L7C88_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9559713.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTK"
BASE COUNT           67 a           46 c           27 g           80 t
ORIGIN      
        1 aattttgtag tgtagctttt gccacctcca accaagcctt cccaaccatg atagttataa
       61 atccttaccc aatgtctaac cagtgtacga tttatttgat atttatgtgc aagatatttg
      121 tagccgcctt cgttatttaa atagtctgaa actacttttt tcttaaaaac aaatgtatat
      181 ttccgcaaaa aaagcacccc ttttaattag atttctagtc
//
LOCUS       DAFTHM010000313          220 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.328, whole genome shotgun sequence.
ACCESSION   DAFTHM010000313 DAFTHM010000000
VERSION     DAFTHM010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.328"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>220
                     /locus_tag="L7C88_002970"
     CDS             <1..>220
                     /locus_tag="L7C88_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9559714.1"
                     /translation="METNGLSIQETAKKFNIGSNRTLSKWIEQYEEGGASSLESQKRG
                     RKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT           90 a           31 c           43 g           56 t
ORIGIN      
        1 atggaaacaa atggtctttc tatccaagaa actgctaaaa aatttaatat cggttcaaat
       61 agaactctaa gtaaatggat agagcaatat gaagaaggcg gtgcttcttc acttgagagc
      121 caaaaaaggg gcagaaaaat tagtatgaat tccaagctaa acattcctaa aaaacttaaa
      181 gatgagtctc ttgaagaaga agttattcgt ttaagagcag
//
LOCUS       DAFTHM010000314          217 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.330, whole genome shotgun sequence.
ACCESSION   DAFTHM010000314 DAFTHM010000000
VERSION     DAFTHM010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.330"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..160
                     /locus_tag="L7C88_002971"
     CDS             <1..160
                     /locus_tag="L7C88_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBP9559715.1"
                     /translation="FIYPFRGYVEHVYNHSAIIRIENTMECDKLLAKSKDNLAVVRLV
                     DMEVIKSK"
BASE COUNT           81 a           37 c           42 g           57 t
ORIGIN      
        1 attcatctat ccatttcgtg gatatgtaga acacgtctat aatcactcag cgatcattcg
       61 cattgaaaac acgatggaat gcgacaagtt attagcgaaa agcaaagata atttagcagt
      121 ggtgagatta gttgacatgg aagtaatcaa gagcaaataa aaaaagccgg atcgctccga
      181 ctgatgtaat aaatccgaca agtttattat atcacat
//
LOCUS       DAFTHM010000315          216 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.331, whole genome shotgun sequence.
ACCESSION   DAFTHM010000315 DAFTHM010000000
VERSION     DAFTHM010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..216
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.331"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT           81 a           39 c           38 g           58 t
ORIGIN      
        1 gttcgtttat ccgttcagag gatacgttaa aaagatactg tcaaactcag caatcattcg
       61 tattgaaaat acaatgaagt gtgatcgttc gactgcaaaa cacaagcatt atttagctgt
      121 agcgagatta gttgacatgg aagtaatcaa gagcaaataa aaaaagccgg atcgctccga
      181 ctgattcaat aaatccaaca catttattat atcaca
//
LOCUS       DAFTHM010000316          213 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.332, whole genome shotgun sequence.
ACCESSION   DAFTHM010000316 DAFTHM010000000
VERSION     DAFTHM010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.332"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
BASE COUNT           65 a           27 c           29 g           92 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tga
//
LOCUS       DAFTHM010000317          210 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.333, whole genome shotgun sequence.
ACCESSION   DAFTHM010000317 DAFTHM010000000
VERSION     DAFTHM010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.333"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            50..>210
                     /locus_tag="L7C88_002972"
     CDS             50..>210
                     /locus_tag="L7C88_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBP9559716.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALE"
BASE COUNT           80 a           41 c           32 g           57 t
ORIGIN      
        1 gctacactca aaatagttcc gaccaaagaa ttataaggag tgagtacaaa tgacctatac
       61 ccatcttaca acggatgaac ttgtaataat agagtcttat ttcaaaatga atcaatctgt
      121 tgctaaaact gcccattgct tgaatcgttc aagacaaacg atccataaag tatatctgtt
      181 cttcaagcaa ggaaaatcag ccttagaata
//
LOCUS       DAFTHM010000318          206 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.334, whole genome shotgun sequence.
ACCESSION   DAFTHM010000318 DAFTHM010000000
VERSION     DAFTHM010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.334"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..>206)
                     /locus_tag="L7C88_002973"
     CDS             complement(<1..>206)
                     /locus_tag="L7C88_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559717.1"
                     /translation="IAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRGVQEVLL
                     FITDGLKGMKDTIHQIYPKAKYQH"
BASE COUNT           56 a           42 c           37 g           71 t
ORIGIN      
        1 caatgctgat attttgcttt aggataaatt tgatggatag tatctttcat gccttttaag
       61 ccgtccgtaa taaaaagcaa gacttcttga actcctctgg agttaatatc ctgtagcagc
      121 tcattccaaa cgtatgttga ttcagttgga gcaatcgcat aactcagtac ttctttagtg
      181 ccgtcttctc gtataccaat ggcaat
//
LOCUS       DAFTHM010000319          205 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.335, whole genome shotgun sequence.
ACCESSION   DAFTHM010000319 DAFTHM010000000
VERSION     DAFTHM010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.335"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>205
                     /locus_tag="L7C88_002974"
     CDS             <1..>205
                     /locus_tag="L7C88_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBP9559718.1"
                     /translation="IWLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKL
                     QSVGLYTKTEHRTVKYLNNLIEQ"
BASE COUNT           70 a           40 c           43 g           52 t
ORIGIN      
        1 atatctggtt acgaaagaaa cgggatacgc aagcagccta tgctttctta aaacgactcc
       61 ataaacagtt tggtgagccg aaagcaattg tgaccgataa agcaccttct cttggctccg
      121 cctttagaaa gttacagagt gtgggtttat atactaagac agagcaccga actgtgaagt
      181 atcttaacaa tttaatagaa caaga
//
LOCUS       DAFTHM010000320          205 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.denovo.336, whole genome shotgun sequence.
ACCESSION   DAFTHM010000320 DAFTHM010000000
VERSION     DAFTHM010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.denovo.336"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..>205
                     /locus_tag="L7C88_002975"
     CDS             <1..>205
                     /locus_tag="L7C88_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559719.1"
                     /translation="LVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQI
                     MNRFRTSHSENQKKYRRLKRYWKL"
BASE COUNT           62 a           49 c           38 g           56 t
ORIGIN      
        1 ctagtgatgg acatgaatgc cagctattgt cagttgctta aaacagtctt tccaaatgcg
       61 gagatcgtaa ctgaccgctt tcatattgtc caacacatca atcgcagctt caatcaatta
      121 cgtgtccaga tcatgaatcg ttttcgaacc tcacactctg aaaatcagaa gaagtaccgt
      181 cggctcaagc gatattggaa actct
//
LOCUS       DAFTHM010000321         5985 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.130, whole genome shotgun sequence.
ACCESSION   DAFTHM010000321 DAFTHM010000000
VERSION     DAFTHM010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.130"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(40..1026)
                     /locus_tag="L7C88_002976"
                     /pseudo
     CDS             complement(40..1026)
                     /locus_tag="L7C88_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
     gene            1178..1873
                     /gene="vanR"
                     /locus_tag="L7C88_002977"
     CDS             1178..1873
                     /gene="vanR"
                     /locus_tag="L7C88_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBP9559720.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1851..3005
                     /locus_tag="L7C88_002978"
     CDS             1851..3005
                     /locus_tag="L7C88_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBP9559721.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            3220..4188
                     /locus_tag="L7C88_002979"
     CDS             3220..4188
                     /locus_tag="L7C88_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBP9559722.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            4181..5212
                     /gene="vanA"
                     /locus_tag="L7C88_002980"
     CDS             4181..5212
                     /gene="vanA"
                     /locus_tag="L7C88_002980"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBP9559723.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            5218..5826
                     /locus_tag="L7C88_002981"
     CDS             5218..5826
                     /locus_tag="L7C88_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBP9559724.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1811 a         1161 c         1347 g         1666 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaacccta tttccgataa ccgtgtattg
       61 aaaggcatct tcgaagccat tatccaatat ttcgcaggct tttgtatatt taggctggtc
      121 gatatattca ccgactaagg cattcttagc tgttcgagcg agttcaatat ccgtaaactt
      181 aaagatcgct tttactgctt ctctaaacgg ttttgaattc ttttttggaa tggaactgaa
      241 gatgtttctt aaaaaatgga cctggcatct ctgccaactt gcgttggtaa atgacttacg
      301 aatcgcagac actaggcctt tatgggcatc agaaatgatg agttctgtcc cctttaggcc
      361 gcgttctttt aagtattcaa agaagatgga ccatgtgtca tcactttctt cattttgaat
      421 catgaagcca atgatttcac ggtcgccacc ttctgttatc ccgatcgcaa tatggcagct
      481 tttagaaagc actcgatggt cctcacggac ttttatgtag agaacatcag tcatcagata
      541 aggataattc gtacctgaga gtgaacggtt ctgccattcg ttgaccatcg ggtctaactg
      601 ctcagtcagg ctagaaacaa aagatttcga tacagatttt ccacatagct cttcaacaat
      661 ctttgaaact ttacgtgtcg aaacgcccga aacatacatc tcaagcattg aagcgagcag
      721 tgccttttca tttcgctgat aacgctcaaa caccgtcggt gaaaattcac catcacgtgt
      781 tctaggcact tttaattcga gtgtacccac acgagtcgta aagtctcgct cataatagcc
      841 atttctttga ctctgacgac tttctgaacg ttcatagtca tcggcttgaa tatattctgt
      901 tcgttgattt tccatcaatt ggttgaaaac agtggttaaa atatttttag aaacatcatc
      961 ttttaccgaa tgttcaataa tactttgaac ctcttcgttg ttcagtgtaa aatgtacttg
     1021 ggtcatgtaa cgtcctcctg ggtatgtttt tgtggttaaa aacattgtac cgtaaaaggg
     1081 ctgttacatg gccttttatc ttttacacaa ttatatggac tttatcctat aatctgataa
     1141 attattaagg gcaaacttat gtgaaagggt gataactatg agcgataaaa tacttattgt
     1201 ggatgatgaa catgaaattg ccgatttggt tgaattatac ttaaaaaacg agaattatac
     1261 ggttttcaaa tactataccg ccaaagaagc attggaatgt atagacaagt ctgagattga
     1321 ccttgccata ttggacatca tgcttcccgg cacaagcggc cttactatct gtcaaaaaat
     1381 aagggacaag cacacctatc cgattatcat gctgaccggg aaagatacag aggtagataa
     1441 aattacaggg ttaacaatcg gcgcggatga ttatataacg aagccctttc gcccactgga
     1501 gttaattgct cgggtaaagg cccagttgcg ccgatacaaa aaattcagtg gagtaaagga
     1561 gcagaacgaa aatgttatcg tccactccgg ccttgtcatt aatgttaaca cccatgagtg
     1621 ttatctgaac gagaagcagt tatcccttac tcccaccgag ttttcaatac tgcgaatcct
     1681 ctgtgaaaac aaggggaatg tggttagctc cgagctgcta tttcatgaga tatggggcga
     1741 cgaatatttc agcaagagca acaacaccat caccgtgcat atccggcatt tgcgcgaaaa
     1801 aatgaacgac accattgata atccgaaata tataaaaacg gtatgggggg ttggttataa
     1861 aattgaaaaa taaaaaaaac gactattcca aactagaacg aaaactttac atgtatatcg
     1921 ttgcaattgt tgtggtagca attgtattcg tgttgtatat tcgttcaatg atccgaggga
     1981 aacttgggga ttggatctta agtattttgg aaaacaaata tgacttaaat cacctggacg
     2041 cgatgaaatt atatcaatat tccatacgga acaatataga tatctttatt tatgtggcga
     2101 ttgtcattag tattcttatt ctatgtcgcg tcatgctttc aaaattcgca aaatactttg
     2161 acgagataaa taccggcatt gatgtactta ttcagaacga agataaacaa attgagcttt
     2221 ctgcggaaat ggatgttatg gaacaaaagc tcaacacatt aaaacggact ctggaaaagc
     2281 gagagcagga tgcaaagctg gccgaacaaa gaaaaaatga cgttgttatg tacttggcgc
     2341 acgatattaa aacgcccctt acatccatta tcggttattt gagcctgctt gacgaggctc
     2401 cagacatgcc ggtagatcaa aaggcaaagt atgtgcatat cacgttggac aaagcgtatc
     2461 gactcgaaca gctaatcgac gagttttttg agattacacg gtataaccta caaacgataa
     2521 cgctaacaaa aacgcacata gacctatact atatgctggt gcagatgacc gatgaatttt
     2581 atcctcagct ttccgcacat ggaaaacagg cggttattca cgcccccgag gatctgaccg
     2641 tgtccggcga ccctgataaa ctcgcgagag tctttaacaa cattttgaaa aacgccgctg
     2701 catacagtga ggataacagc atcattgaca ttaccgcggg cctctccggg gatgtggtgt
     2761 caatcgaatt caagaacact ggaagcatcc caaaagataa gctagctgcc atatttgaaa
     2821 agttctatag gctggacaat gctcgttctt ccgatacggg tggcgcggga cttggattgg
     2881 cgattgcaaa agaaattatt gttcagcatg gagggcagat ttacgcggaa agcaatgata
     2941 actatacgac gtttagggta gagcttccag cgatgccaga cttggttgat aaaaggaggt
     3001 cctaagagat gtatataatt ttttaggaaa atctcaaggt tatctttact ttttcttagg
     3061 aaattaacaa tttaatatta agaaacggct cgttcttaca cggtagactt aataccgtaa
     3121 gaacgagccg ttttcgttct tcagagaaag atttgacaag attaccattg gcatccccgt
     3181 tttatttggt gcctttcaca gaaagggttg gtcttaatta tgaataacat cggcattact
     3241 gtttatggat gtgagcagga tgaggcagat gcattccatg ctctttcgcc tcgctttggc
     3301 gttatggcaa cgataattaa cgccaacgtg tcggaatcca acgccaaatc cgcgcctttc
     3361 aatcaatgta tcagtgtggg acataaatca gagatttccg cctctattct tcttgcgctg
     3421 aagagagccg gtgtgaaata tatttctacc cgaagcatcg gctgcaatca tatagataca
     3481 actgctgcta agagaatggg catcactgtc gacaatgtgg cgtactcgcc ggatagcgtt
     3541 gccgattata ctatgatgct aattcttatg gcagtacgca acgtaaaatc gattgtgcgc
     3601 tctgtggaaa aacatgattt caggttggac agcgaccgtg gcaaggtact cagcgacatg
     3661 acagttggtg tggtgggaac gggccagata ggcaaagcgg ttattgagcg gctgcgagga
     3721 tttggatgta aagtgttggc ttatagtcgc agccgaagta tagaggtaaa ctatgtaccg
     3781 tttgatgagt tgctgcaaaa tagcgatatc gttacgcttc atgtgccgct caatacggat
     3841 acgcactata ttatcagcca cgaacaaata cagagaatga agcaaggagc atttcttatc
     3901 aatactgggc gcggtccact tgtagatacc tatgagttgg ttaaagcatt agaaaacggg
     3961 aaactgggcg gtgccgcatt ggatgtattg gaaggagagg aagagttttt ctactctgat
     4021 tgcacccaaa aaccaattga taatcaattt ttacttaaac ttcaaagaat gcctaacgtg
     4081 ataatcacac cgcatacggc ctattatacc gagcaagcgt tgcgtgatac cgttgaaaaa
     4141 accattaaaa actgtttgga ttttgaaagg agacaggagc atgaatagaa taaaagttgc
     4201 aatactgttt gggggttgct cagaggagca tgacgtatcg gtaaaatctg caatagagat
     4261 agccgctaac attaataaag aaaaatacga gccgttatac attggaatta cgaaatctgg
     4321 tgtatggaaa atgtgcgaaa aaccttgcgc ggaatgggaa aacgacaatt gctattcagc
     4381 tgtactctcg ccggataaaa aaatgcacgg attacttgtt aaaaagaacc atgaatatga
     4441 aatcaaccat gttgatgtag cattttcagc tttgcatggc aagtcaggtg aagatggatc
     4501 catacaaggt ctgtttgaat tgtccggtat cccttttgta ggctgcgata ttcaaagctc
     4561 agcaatttgt atggacaaat cgttgacata catcgttgcg aaaaatgctg ggatagctac
     4621 tcccgccttt tgggttatta ataaagatga taggccggtg gcagctacgt ttacctatcc
     4681 tgtttttgtt aagccggcgc gttcaggctc atccttcggt gtgaaaaaag tcaatagcgc
     4741 ggacgaattg gactacgcaa ttgaatcggc aagacaatat gacagcaaaa tcttaattga
     4801 gcaggctgtt tcgggctgtg aggtcggttg tgcggtattg ggaaacagtg ccgcgttagt
     4861 tgttggcgag gtggaccaaa tcaggctgca gtacggaatc tttcgtattc atcaggaagt
     4921 cgagccggaa aaaggctctg aaaacgcagt tataaccgtt cccgcagacc tttcagcaga
     4981 ggagcgagga cggatacagg aaacggcaaa aaaaatatat aaagcgctcg gctgtagagg
     5041 tctagcccgt gtggatatgt ttttacaaga taacggccgc attgtactga acgaagtcaa
     5101 tactctgccc ggtttcacgt catacagtcg ttatccccgt atgatggccg ctgcaggtat
     5161 tgcacttccc gaactgattg accgcttgat cgtattagcg ttaaaggggt gataagcatg
     5221 gaaataggat ttactttttt agatgaaata gtacacggtg ttcgttggga cgctaaatat
     5281 gccacttggg ataatttcac cggaaaaccg gttgacggtt atgaagtaaa tcgcattgta
     5341 gggacatacg agttggctga atcgcttttg aaggcaaaag aactggctgc tacccaaggg
     5401 tacggattgc ttctatggga cggttaccgt cctaagcgtg ctgtaaactg ttttatgcaa
     5461 tgggctgcac agccggaaaa taacctgaca aaggaaagtt attatcccaa tattgaccga
     5521 actgagatga tttcaaaagg atacgtggct tcaaaatcaa gccatagccg cggcagtgcc
     5581 attgatctta cgctttatcg attagacacg ggtgagcttg taccaatggg gagccgattt
     5641 gattttatgg atgaacgctc tcatcatgcg gcaaatggaa tatcatgcaa tgaagcgcaa
     5701 aatcgcagac gtttgcgctc catcatggaa aacagtgggt ttgaagcata tagcctcgaa
     5761 tggtggcact atgtattaag agacgaacca taccccaata gctattttga tttccccgtt
     5821 aaataaactt ttaaccgttg cacggacaaa ctatataagc taactctttc ggcaggaaac
     5881 ccgacgtatg taactggttc ttagggaatt tatatatagt agatagtatt gaagatgtaa
     5941 ggcagagggt tctgttgcaa agttttaaat aaagaataaa atccc
//
LOCUS       DAFTHM010000322         3646 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.164, whole genome shotgun sequence.
ACCESSION   DAFTHM010000322 DAFTHM010000000
VERSION     DAFTHM010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.164"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            239..703
                     /locus_tag="L7C88_002982"
     CDS             239..703
                     /locus_tag="L7C88_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBP9559725.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            687..1316
                     /locus_tag="L7C88_002983"
     CDS             687..1316
                     /locus_tag="L7C88_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBP9559726.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            1670..3148
                     /gene="msr(C)"
                     /locus_tag="L7C88_002984"
     CDS             1670..3148
                     /gene="msr(C)"
                     /locus_tag="L7C88_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBP9559727.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            3195..3641
                     /locus_tag="L7C88_002985"
     CDS             3195..3641
                     /locus_tag="L7C88_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBP9559728.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
BASE COUNT         1238 a          592 c          756 g         1060 t
ORIGIN      
        1 attatctact gcagaagagc tatcttctat agtttgataa gaatcaataa tcttggtttt
       61 agcgttgtgc tttctttatc attttttccg ttcattctac aaaaaatttc ttttctctat
      121 acttttctat tgagagcgtt ttttttatta cacagctgat tctttgactt ttttcttttt
      181 ttattctatt attgacaagt caatcgttga cgagtcaatt attagaaagg aggaaattat
      241 gtctttagaa gagattagtc accttttata tcaaatcaaa ttagccgatc aaaaaatcgt
      301 ccagatcttt gaagaaaata tcggtataag tcttactaga tacgagatca tgatgagact
      361 gaaagaagaa aatccattgc tacaaagcag tttgcaagaa aagttgcaga ttgatcaagg
      421 agcagttact cgtcatctga aggtattgga agcaaatggc tatgtttcgc gtcagagaaa
      481 tcctcagaac aaccgggaag tgtatgtagc gctaacagaa aaagcccaga agaaaatcaa
      541 gcattgtgaa atggaccata aagatacagg ttccgtgcta tccccggctt tcagcgatgt
      601 agaaatgaaa caatttctaa cacttttaga taaattgaat acccaacttt gcaatataac
      661 aacagaaacg aaagaggtta ataataatgg aacaaaaaaa tgatttttca acaattatga
      721 ctggtagaag atccgttcgc gtatatgatg aaacatacaa aatcccacac gaagaaatgc
      781 tggaaatgat caaagaagcg acgactgcac cttcttctgt caatatgaaa ccatggcgct
      841 ttgtggtcgc tgaaagcgag gaagcaaaag aaatcttgcg tcctttgatc cgtttcaata
      901 cgagacaaaa tgatacttct tctgcaatgg tcatgatttt tggcgatatg caatgttacg
      961 aatatggcga agaaatctac aaccaagctt acgaatcagg gaagatgcca aaagaagtca
     1021 gagatcaaca attagctgcg atcattcctt attacaagag tttttcaaga gaagaaatga
     1081 acgatgtagt caaagtcgat tctagcttag cggctatgca attcatgtta gttgcgcgtg
     1141 atcatggcta tgaaacaaat ccaattggtg gattcgaagc agatcagttg gcagaggcat
     1201 ttggtttgga taaagaccgt tatgttccag ttattatttt atcaatagga aaagcggtag
     1261 aagaaggtta cgagtctgtt cgtttagcac cagaaaagat cactatgttc gaataaaagg
     1321 ttttcagtta ctattcagta gctattgctt tttttgaatc gtgtgtggta acctaataaa
     1381 aaaggaggtc ggaaaaatga ctgcatcgat gaaattacgt ttcgaacttt tgaataacaa
     1441 ctaaataaat tcaaaagaca tgtataaaca acaatttcat ggatggagta tgtccatttt
     1501 ttcgaacgac agtagaatag gtgaaagcta tgacagattt ggtgatttag tcatagttat
     1561 ttcgttcaga gtaggaaaag atgtgatgca gtttttttgc aaacagattt ttctgctctt
     1621 ttttagtatc gataattgtt gttttacatg aaataggagt gtaaaacata tggaaaattt
     1681 agcagtaaat ataacaaatc tacaagtcag ctttggcaac cagctagaac tatctattga
     1741 ttctcttcgt gtctatcagc aagatcgtat agggatcata ggagaaaatg gtgtcggtaa
     1801 atcgactttg ctcaaactaa tagccggtga actttttccc gatcatggga aaatccaaac
     1861 agagatcacc ttcaactacc tgcctcaatt aacctatctc gctgaagcaa aggacctaaa
     1921 tttggaatta gccagtcatt tccagttaag actggaagaa acttcagagc ggaaatggag
     1981 cggaggggaa gaacgaaaga tcgagttgat acgtcttctt tcttcttatg aacaagggat
     2041 gcttctagac gagccaacaa cccatctaga tagaaaaagt attgatcgac tgattgaaga
     2101 gcttcgttat tattatggta cgctggtttt tgttagtcat gatcgctatt ttctagatga
     2161 gctagcatcg aaaatctggg aagtaaaaga cggagaaatc cgagagtttt cggggaatta
     2221 tagtgcctat ctcactcaaa aggaattgga gaaaaagact cagctacgag aagcagagtc
     2281 gatcatgaaa gagaaaaaac gattggaaaa atcgatccaa gaaaagaaaa aacaagcgga
     2341 aaagttggaa aaagtgtcca gtaaaaagaa aaagcaacaa atcagactgg atcggttgtc
     2401 ttcctctaaa caaaaagaca gtgtacaaaa agccatccaa aagaatgcga aaacattaga
     2461 gagaagactc caaaaaatag gagaaacaac caagccgcag cagatgaaac aaatccgttt
     2521 tccagtacca aaatctcttg aactccacag ccgctatccc atcatgggac aaaatgtcca
     2581 attggaaaga agtgggagaa cattactggt aaatggtgat tttcagtttt ctttaggtaa
     2641 aaaaatcgcg attgtcggtg aaaatggttc aggtaagaca accttattag aacatatccg
     2701 caaacaagga gaaggaatcc ttctctctcc gaaagtaagc tttcaagtat atcagcaaaa
     2761 gggttatcaa atgacatctg aagaatccat cattcgtttt gtcatgagac aaacagagtt
     2821 ttcagaatcg cttgtccgta gtttgctgaa tcacttaggg tttgctcagg aaactttgac
     2881 gaaaccgtta tgtacattaa gtgggggaga agcgacccgt ctgacgattg ctttgctttt
     2941 tactaagcca agtaatgtgt tgctgttaga tgaaccgact aattttattg atatggcaac
     3001 gatcgaagct ttagagaagc taatgcaaat atatccggga acgattttgt ttacttctca
     3061 tgattcttac tttgtcgagc gtacggctga tgaagtttat gaaataaaag ggcagaaaat
     3121 aaaaaaagta cttacgagaa atttttaaat gtgctacgat gattttcgtg acaaatttaa
     3181 aggagtggta cagattgcct acaaataaaa aagaaggaat aatttttaca acaatgatgt
     3241 gttttttgat ggtcttgggg atgagcgcgt ataatttatg gctgcatcaa gatcttcatt
     3301 tatcaagttt gttgattggt ctagtgcctg gattcgtggt ggctttcatt ttggatgtct
     3361 tcatcatcgg tgtgctggcg aaaaaaattg cctttaaact accagtaaat ccagaaagca
     3421 aggtccaaat gatcttaact atttcatgct tgatggtttt aggaatggtg acatgtatgt
     3481 ctttattcgg tgtgatcatg gaacaaggaa tacctgatca attattctct gcttatatga
     3541 atgcttggaa aatgaatgtg attgccgctt taccgttgca gttgatcatc gttggcccgc
     3601 tttcaagaag tgtgctaaaa gcaattcaaa gtaatgaatg atggaa
//
LOCUS       DAFTHM010000323         3646 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.165, whole genome shotgun sequence.
ACCESSION   DAFTHM010000323 DAFTHM010000000
VERSION     DAFTHM010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.165"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            239..703
                     /locus_tag="L7C88_002986"
     CDS             239..703
                     /locus_tag="L7C88_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBP9559729.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            687..1316
                     /locus_tag="L7C88_002987"
     CDS             687..1316
                     /locus_tag="L7C88_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBP9559730.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            1670..3148
                     /gene="msr(C)"
                     /locus_tag="L7C88_002988"
     CDS             1670..3148
                     /gene="msr(C)"
                     /locus_tag="L7C88_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBP9559731.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKENKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            3195..3641
                     /locus_tag="L7C88_002989"
     CDS             3195..3641
                     /locus_tag="L7C88_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBP9559732.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
BASE COUNT         1237 a          592 c          756 g         1061 t
ORIGIN      
        1 attatctact gcagaagagc tatcttctat agtttgataa gaatcaataa tcttggtttt
       61 agcgttgtgc tttctttatc attttttccg ttcattctac aaaaaatttc ttttctctat
      121 acttttctat tgagagcgtt ttttttatta cacagctgat tctttgactt ttttcttttt
      181 ttattctatt attgacaagt caatcgttga cgagtcaatt attagaaagg aggaaattat
      241 gtctttagaa gagattagtc accttttata tcaaatcaaa ttagccgatc aaaaaatcgt
      301 ccagatcttt gaagaaaata tcggtataag tcttactaga tacgagatca tgatgagact
      361 gaaagaagaa aatccattgc tacaaagcag tttgcaagaa aagttgcaga ttgatcaagg
      421 agcagttact cgtcatctga aggtattgga agcaaatggc tatgtttcgc gtcagagaaa
      481 tcctcagaac aaccgggaag tgtatgtagc gctaacagaa aaagcccaga agaaaatcaa
      541 gcattgtgaa atggaccata aagatacagg ttccgtgcta tccccggctt tcagcgatgt
      601 agaaatgaaa caatttctaa cacttttaga taaattgaat acccaacttt gcaatataac
      661 aacagaaacg aaagaggtta ataataatgg aacaaaaaaa tgatttttca acaattatga
      721 ctggtagaag atccgttcgc gtatatgatg aaacatacaa aatcccacac gaagaaatgc
      781 tggaaatgat caaagaagcg acgactgcac cttcttctgt caatatgaaa ccatggcgct
      841 ttgtggtcgc tgaaagcgag gaagcaaaag aaatcttgcg tcctttgatc cgtttcaata
      901 cgagacaaaa tgatacttct tctgcaatgg tcatgatttt tggcgatatg caatgttacg
      961 aatatggcga agaaatctac aaccaagctt acgaatcagg gaagatgcca aaagaagtca
     1021 gagatcaaca attagctgcg atcattcctt attacaagag tttttcaaga gaagaaatga
     1081 acgatgtagt caaagtcgat tctagcttag cggctatgca attcatgtta gttgcgcgtg
     1141 atcatggcta tgaaacaaat ccaattggtg gattcgaagc agatcagttg gcagaggcat
     1201 ttggtttgga taaagaccgt tatgttccag ttattatttt atcaatagga aaagcggtag
     1261 aagaaggtta cgagtctgtt cgtttagcac cagaaaagat cactatgttc gaataaaagg
     1321 ttttcagtta ctattcagta gctattgctt tttttgaatc gtgtgtggta acctaataaa
     1381 aaaggaggtc ggaaaaatga ctgcatcgat gaaattacgt ttcgaacttt tgaataacaa
     1441 ctaaataaat tcaaaagaca tgtataaaca acaatttcat ggatggagta tgtccatttt
     1501 ttcgaacgac agtagaatag gtgaaagcta tgacagattt ggtgatttag tcatagttat
     1561 ttcgttcaga gtaggaaaag atgtgatgca gtttttttgc aaacagattt ttctgctctt
     1621 ttttagtatc gataattgtt gttttacatg aaataggagt gtaaaacata tggaaaattt
     1681 agcagtaaat ataacaaatc tacaagtcag ctttggcaac cagctagaac tatctattga
     1741 ttctcttcgt gtctatcagc aagatcgtat agggatcata ggagaaaatg gtgtcggtaa
     1801 atcgactttg ctcaaactaa tagccggtga actttttccc gatcatggga aaatccaaac
     1861 agagatcacc ttcaactacc tgcctcaatt aacctatctc gctgaagcaa aggacctaaa
     1921 tttggaatta gccagtcatt tccagttaag actggaagaa acttcagagc ggaaatggag
     1981 cggaggggaa gaacgaaaga tcgagttgat acgtcttctt tcttcttatg aacaagggat
     2041 gcttctagac gagccaacaa cccatctaga tagaaaaagt attgatcgac tgattgaaga
     2101 gcttcgttat tattatggta cgctggtttt tgttagtcat gatcgctatt ttctagatga
     2161 gctagcatcg aaaatctggg aagtaaaaga cggagaaatc cgagagtttt cggggaatta
     2221 tagtgcctat ctcactcaaa aggaattgga gaaaaagact cagctacgag aagcagagtc
     2281 gatcatgaaa gagaataaac gattggaaaa atcgatccaa gaaaagaaaa aacaagcgga
     2341 aaagttggaa aaagtgtcca gtaaaaagaa aaagcaacaa atcagactgg atcggttgtc
     2401 ttcctctaaa caaaaagaca gtgtacaaaa agccatccaa aagaatgcga aaacattaga
     2461 gagaagactc caaaaaatag gagaaacaac caagccgcag cagatgaaac aaatccgttt
     2521 tccagtacca aaatctcttg aactccacag ccgctatccc atcatgggac aaaatgtcca
     2581 attggaaaga agtgggagaa cattactggt aaatggtgat tttcagtttt ctttaggtaa
     2641 aaaaatcgcg attgtcggtg aaaatggttc aggtaagaca accttattag aacatatccg
     2701 caaacaagga gaaggaatcc ttctctctcc gaaagtaagc tttcaagtat atcagcaaaa
     2761 gggttatcaa atgacatctg aagaatccat cattcgtttt gtcatgagac aaacagagtt
     2821 ttcagaatcg cttgtccgta gtttgctgaa tcacttaggg tttgctcagg aaactttgac
     2881 gaaaccgtta tgtacattaa gtgggggaga agcgacccgt ctgacgattg ctttgctttt
     2941 tactaagcca agtaatgtgt tgctgttaga tgaaccgact aattttattg atatggcaac
     3001 gatcgaagct ttagagaagc taatgcaaat atatccggga acgattttgt ttacttctca
     3061 tgattcttac tttgtcgagc gtacggctga tgaagtttat gaaataaaag ggcagaaaat
     3121 aaaaaaagta cttacgagaa atttttaaat gtgctacgat gattttcgtg acaaatttaa
     3181 aggagtggta cagattgcct acaaataaaa aagaaggaat aatttttaca acaatgatgt
     3241 gttttttgat ggtcttgggg atgagcgcgt ataatttatg gctgcatcaa gatcttcatt
     3301 tatcaagttt gttgattggt ctagtgcctg gattcgtggt ggctttcatt ttggatgtct
     3361 tcatcatcgg tgtgctggcg aaaaaaattg cctttaaact accagtaaat ccagaaagca
     3421 aggtccaaat gatcttaact atttcatgct tgatggtttt aggaatggtg acatgtatgt
     3481 ctttattcgg tgtgatcatg gaacaaggaa tacctgatca attattctct gcttatatga
     3541 atgcttggaa aatgaatgtg attgccgctt taccgttgca gttgatcatc gttggcccgc
     3601 tttcaagaag tgtgctaaaa gcaattcaaa gtaatgaatg atggaa
//
LOCUS       DAFTHM010000324         2539 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.180, whole genome shotgun sequence.
ACCESSION   DAFTHM010000324 DAFTHM010000000
VERSION     DAFTHM010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.180"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            complement(<1..340)
                     /locus_tag="L7C88_002990"
     CDS             complement(<1..340)
                     /locus_tag="L7C88_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBP9559733.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMY"
     gene            702..1742
                     /locus_tag="L7C88_002991"
     CDS             702..1742
                     /locus_tag="L7C88_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBP9559734.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            1840..2028
                     /locus_tag="L7C88_002992"
     CDS             1840..2028
                     /locus_tag="L7C88_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBP9559735.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(2086..2439)
                     /locus_tag="L7C88_002993"
     CDS             complement(2086..2439)
                     /locus_tag="L7C88_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBP9559736.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
BASE COUNT          831 a          431 c          411 g          866 t
ORIGIN      
        1 tgtacatttt ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa
       61 aaatttcttc ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac
      121 aaccattaaa ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg
      181 ctcttccgat tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat
      241 ttttaacata ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca
      301 ctctattctt atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa
      361 ctaatttacc atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt
      421 tagttgaata agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat
      481 tttcattcaa ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat
      541 gtaagttaaa atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa
      601 aactgaacta cttacttgca tatatacgcc tttatagtgg agtactacat ttacgagatt
      661 cggttagagt atcagaaaaa gaaaaaataa aagttacaga aatgtatact tcaataaatg
      721 gtgaattatg taagattgat agagcttatt ctggagaaat tgttattttg caaaatgagt
      781 ttttgaagtt aaatagtgtt cttggagata caaaactatt gccacagaga aaaaagattg
      841 aaaatccgca ccctctacta caaacaactg ttgaaccgag taaacctgaa cagagagaaa
      901 tgttgcttga tgcccttttg gaaatctcag atagtgatcc gcttctacga tattacgtgg
      961 attctacgac acatgaaatt atactttctt tcttagggaa agtacaaatg gaagtgatta
     1021 gtgcactgtt gcaagaaaag tatcatgtgg agatagaact aaaagagcct acagtcattt
     1081 atatggagag accgttaaaa aatgcagaat ataccattca catcgaagtg ccgccaaatc
     1141 ctttctgggc ttccattggt ttatctgtat caccgcttcc gttgggaagt ggaatgcagt
     1201 atgagagctc ggtttctctt ggatacttaa atcaatcatt tcaaaatgca gttatggaag
     1261 ggatacgcta tggttgcgaa caaggattat atggttggaa tgtgacggat tgtaaaatct
     1321 gttttaagta cggtttatac tatagccctg ttagtactcc agcagatttt cggatgctta
     1381 ctcctattgt actggagcaa gcctttagaa aagctggaac agaattgtta gagccatatc
     1441 ttagttttaa agtttatgca ccacaggaat atctttcacg ggcatataac gatgctccca
     1501 aatattgtgc aaatatcgta aatactcaac tgaaaaataa tgaggtcatt attattggag
     1561 aaattcctgc tcgatgtatt caagattatc gcaatgattt aacttttttt acaaatgggc
     1621 ttagtgtttg tttagcagag ctaaaaggat atcaggttac cactggcgaa cctgtttgcc
     1681 agacccgtcg tctaaatagt cggatagata aagtaagata tatgttcaat aaaataactt
     1741 agtgcgtttt atgttgttat ataaatatgg tttcttatta aataagatga aatattcttt
     1801 aatatagatt tgaattaaag tggaaaggag gagattgtta ttataaacta caagtggata
     1861 ttgtgtccta tttgtggaaa taaaacaaga ctacgaatac gagtggatac tatacttaaa
     1921 aatttccctt tatactgccc caaatgtaag aacgaaactt taattaatgt tcaaaaaatg
     1981 aatataataa caatcaaaga gccagacgcc aagacgcaga gccgataatt tgagaaatga
     2041 aactctcatc ttatcggctc tttttgttta tctgaatttt actgactagc cttcaatatt
     2101 tcttgcttca ttgatacctt ttgctagtgc ttccattaag gatagttctt tgtctgtaaa
     2161 gctatccatg tatttttcta cctgtaacct tcgagtgctt ttaatcaaat tatctgtagg
     2221 taagaaaaat tcatcaatag atacatggag taatgataca agatcataca gcacttgtgt
     2281 acttgggtgt tgtcctttgt tttctatatt tgttaaataa cgtgggtcaa tttcaatcat
     2341 tgttcccact tgttcacgag tgagaccccg tttcattcga gcctctttaa tcgctaaacc
     2401 aacggctcta aaatcgtatt tatcttcttt tttacgcata ctaaatcacc tctatacatt
     2461 ttactgttcc tatataacca taaacaggta tagaaaaaca tgttatatag tttatgagtt
     2521 cctatagaac actgtggaa
//
LOCUS       DAFTHM010000325         2474 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.181, whole genome shotgun sequence.
ACCESSION   DAFTHM010000325 DAFTHM010000000
VERSION     DAFTHM010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.181"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            292..1794
                     /gene="eat(A)"
                     /locus_tag="L7C88_002994"
     CDS             292..1794
                     /gene="eat(A)"
                     /locus_tag="L7C88_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBP9559737.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            1822..2388
                     /locus_tag="L7C88_002995"
     CDS             1822..2388
                     /locus_tag="L7C88_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBP9559738.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
BASE COUNT          837 a          435 c          542 g          660 t
ORIGIN      
        1 acttagcaga tttttcacca tcctcccgaa gtagttgaca aaatcatttt ctttatgcta
       61 tcgtaatttc aaatatagga caaagtgagg gatccgtgca ttgaaaaatt aagtcgattg
      121 atgaaagctg cattcagact gtaccttgtg gagacaagga agcagtgtgc agattttcgg
      181 gattggcttg gttttttcga tgtatgggtc tttttgtgtg tatccaaccc ttgcatcctc
      241 tttagccagt tctgaaaata ggactggtct ttttttacga ggtgatggaa aatgtctaaa
      301 atcgaaataa aaaatctgac attcggctac gacagccaag gcacattatt atttgaacaa
      361 gcaaatctaa attttgacac acaatggaaa ctaggactta tcggacgaaa cggtcgagga
      421 aagacaactt tactgaatat tctacaaaac aaactacctt atcaagggca agtaatccat
      481 cagcaagaat ttgcctattt cccgcaacag acaaaagata aagaacgttt aacctattac
      541 gtgttaaatg atattacgga ttttgagata tgggaaatcg aaagagagct ccaattgatg
      601 caaacagatc ctgaaatctt atggagagaa ttcagcacac tatcgggggg agagaagaca
      661 aaagtcctac tggcactttt atttgtggat gacactcatt tcccgttaat cgatgaacca
      721 acgaatcatt tggatatctc tggtagaaaa caagtagcgg cttatttgaa aaagaaaaaa
      781 caaggcttca tcgtggtcag ccatgaccgg ggatttatcg atgaagtagt ggaccatgtt
      841 ttagcaatcg aaaaaagtca actggaactt tatcaaggga atttctctat ctatgaagaa
      901 cagaaaaaac ttcgtgatga atttgaaatg gctcaaaatg aaaaattgaa aaaagaagtc
      961 agtaggctaa agaaaacagc agctgaaaaa gccgaatggt ctcgttcccg agaaggagat
     1021 aaaacaaaga aacaagtcgg attcatcgat actgaatcta gacgagtgaa taaaggagca
     1081 gtgggtgctg atgctgcacg gacgatgaaa cgatccaaag caatcgtgaa tcggatggag
     1141 acccagatca gcgagaaaga aaaactatta aaagatatcg aatatatcga ttctttgacg
     1201 atgaatagcc aagcgtctca ccataagcga cttttaagcg tagaagatct tcaattaggg
     1261 tatgaaaatc tgttattcga gccaattcat tttacaatcg agcctcatca gcgggtggcg
     1321 atttcaggtc ctaacggtgc aggaaagtca tccattatcc attatcttct gggggcattc
     1381 aacggcaagg ttataggaga aaaataccag ccaaaacatc tgagcattag ttatgcaagc
     1441 caaaattatg aagacaatcg aggaacgttg gcggaatttg cagagaaaaa ccaagtagac
     1501 taccaagcat ttttgaacaa cctccgaaag cttgggatgg aaagagatgt ttttcataac
     1561 aagatcgagc agatgagtat gggccaacgg aaaaaagtgg aattggctaa atctttatca
     1621 cagccagctg aactatatac atgggatgaa ccattgaatt atttggatgt cttcaatcaa
     1681 gaacaattag aacaactgat cttgaacgtg aaacctgcca tgttactagt ggaacatgat
     1741 caaaccttcc tggataaagt atctactgag attatttctc ttgagagaat ctaacccttg
     1801 taatctcaag aacaacaagg tatggttaag gggaactttg ccaacgaagg agagaatcac
     1861 atgctttatg taacgagaca cggagaaaca acttggaacg cacaaggatt agtttgcgga
     1921 cgggcagatg tgccgctgac tgaaaaagga cagatgcagg cacagaaact agcagaaaag
     1981 gtagtagatt tgcctgttcc aatcacgaaa atcatccatt cccctcttca acgagcaaga
     2041 gatacagcac aagcagttgc tgatcgtctc agcttgccgc tgaccgttga tgaacgattg
     2101 gtagaaatgg attttgggga ttatgatgga ctgccaagca aagatgagaa ctttcaaaaa
     2161 gcacgtttag cgttcgctgt acgattccca aatggggagt cagtcttaga tgtgtatgca
     2221 cggatcgttc ctttattgaa agaatgcatc gaagacgaag aaaatgtcta tctgttagtt
     2281 tgccataatg ccttgataag agtgatcaat gcttattttc atccgatgcc taatgagggg
     2341 ttctttacat tcatggtaga taatacagaa ttggtttctt atgagtaatt atgtttttgt
     2401 gttatttaaa taaaatattt caaggcactg cttttgctta gcagtgcctt ttttaggtta
     2461 tgacaattct tttg
//
LOCUS       DAFTHM010000326         1804 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.204, whole genome shotgun sequence.
ACCESSION   DAFTHM010000326 DAFTHM010000000
VERSION     DAFTHM010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.204"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..266
                     /locus_tag="L7C88_002996"
     CDS             <1..266
                     /locus_tag="L7C88_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBP9559739.1"
                     /translation="VINFNSIAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKP
                     KKSSRSEEILIKTLKRRVMELEKENKKLQNQIQKLYGDLYNKE"
     gene            420..1202
                     /locus_tag="L7C88_002997"
     CDS             420..1202
                     /locus_tag="L7C88_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)-Ia"
                     /protein_id="HBP9559740.1"
                     /translation="MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRI
                     NSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYP
                     PKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
                     DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
     gene            complement(1328..>1804)
                     /locus_tag="L7C88_002998"
     CDS             complement(1328..>1804)
                     /locus_tag="L7C88_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     ErmA"
                     /protein_id="HBP9559741.1"
                     /translation="LKFSFPKHINYKIYGNIPYNISTDIVKRITFESQAKYSYLIVEK
                     GFAKRLQNLQRALGLLLMVEMDIKMLKKVPPLYFHPKPSVDSVLIVLERHQPLISKKD
                     YKKYRSFVYKWVNREYRVLFTKNQFRQALKHANVTNINKLSKEQFLSIFNSYKLFH"
BASE COUNT          643 a          259 c          336 g          566 t
ORIGIN      
        1 aagttattaa ttttaattca atagcaaagg aagctaatgt ttctaaatca tggctttata
       61 aggaacacga tattaggcaa agaatcgaat cccttcgtga gcgtcaaata acagcaaatg
      121 tagtctcaaa acccaagaaa agttctcgtt cggaggaaat ccttattaaa accttaaaaa
      181 gaagagtaat ggaattagaa aaagaaaata aaaaattaca gaaccaaatt caaaaattat
      241 atggagatct gtataataaa gaataattat taatctgtag acaaattgtg aaaggatgta
      301 cttaaacgct aacggtcagc tttattgaac agtcatttag gtatatgtcc aatctagggt
      361 aagtaaattg agtatcaata taaactttat atgaacataa tcagttacga ggtgaaatca
      421 tgagcaattt gattaacgga aaaataccaa atcaagcgat tcaaacatta aaaatcgtaa
      481 aagatttatt tggaagttca atagttggag tatatctatt tggttcagca gtaaatggtg
      541 gtttacgcat taacagcgat gtagatgttc tagtcgtcgt gaatcatagt ttacctcaat
      601 taactcgaaa aaaactaaca gaaagactaa tgactatatc aggaaagatt ggaaatacgg
      661 attctgttag accacttgaa gttacggtta taaataggag tgaagttgtc ccttggcaat
      721 atcctccaaa aagagaattt atatacggtg agtggctcag gggtgaattt gagaatggac
      781 aaattcagga accaagctat gatcctgatt tggctattgt tttagcacaa gcaagaaaga
      841 atagtatttc tctatttggt cctgattctt caagtatact tgtctccgta cctttgacag
      901 atattcgaag agcaattaag gattctttgc cagaactaat tgaggggata aaaggtgatg
      961 agcgtaatgt aattttaacc ctagctcgaa tgtggcaaac agtgactact ggtgaaatta
     1021 cctcgaaaga tgtcgctgca gaatgggcta tacctctttt acctaaagag catgtaactt
     1081 tactggatat agctagaaaa ggctatcggg gagagtgtga tgataagtgg gaaggactat
     1141 attcaaaggt gaaagcactc gttaagtata tgaaaaattc tatagaaact tctctcaatt
     1201 aggctaattt tattgcaata acaggtgctt acttttaaaa ctactgattt attgataaat
     1261 attgaacaat ttttgggaag aataaagcgt cctcttgtga aattagagaa cgctttatta
     1321 ctttaattta gtgaaacaat ttgtaactat tgaaaataga aagaaattgt tccttcgata
     1381 gtttattaat attagtgaca tttgcatgct tcaaagcctg tcggaattgg tttttagtga
     1441 aaagaacacg atattcacgg tttacccact tataaacaaa agatcgatac tttttgtagt
     1501 ccttctttga aatcaatggt tgatgtcgtt caagaacaat caatacagag tctacacttg
     1561 gcttaggatg aaaatatagt ggtggtactt ttttgagcat ttttatatcc atctccacca
     1621 ttaatagtaa acccaaagct cgttgcagat tttgcaatct tttcgcaaat cccttctcaa
     1681 cgataagata gctatattta gcctgacttt caaaggtaat tcttttgaca atatccgtac
     1741 tgatgttata aggaatatta ccatatatct tatagtttat atgttttggg aaggaaaatt
     1801 ttag
//
LOCUS       DAFTHM010000327         1504 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.217, whole genome shotgun sequence.
ACCESSION   DAFTHM010000327 DAFTHM010000000
VERSION     DAFTHM010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.217"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            262..345
                     /locus_tag="L7C88_002999"
                     /pseudo
     CDS             262..345
                     /locus_tag="L7C88_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            394..477
                     /locus_tag="L7C88_003000"
     CDS             394..477
                     /locus_tag="L7C88_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HBP9559742.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            602..1339
                     /gene="erm(B)"
                     /locus_tag="L7C88_003001"
     CDS             602..1339
                     /gene="erm(B)"
                     /locus_tag="L7C88_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBP9559743.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          551 a          224 c          245 g          484 t
ORIGIN      
        1 atttgtatcg ataagaaata gatttaaaaa tttcgctgtt attttgtaca tttaacttga
       61 cggtgacatc tctctattgt gagttattag tggtacagtt ttcaaccgtt ttaattataa
      121 aaaagtggtg catttttaaa ttggcacaaa caggtaacgg ttattgcagg tgtatttctt
      181 atctatgggt ttaacatgga ttttatcatt aaaatcatga gtattgtccg agagtgattg
      241 gtcttgcgta tggttaaccc taaagttatg gaaataagac ttagaagcaa acttaagagt
      301 gtgttgatag tgcattatct taaaattttg tataatagga attgaagtta aattagatgc
      361 taaaaatttg taattaagaa ggagggattc gtcatgttgg tattccaaat gcgttatgta
      421 gataaaacat ctactgtttt gaaacagact aaaaacagtg attacgcaga taaataaata
      481 cgttagatta attcctacca gtgactaatc ttatgacttt ttaaacagat aactaaaatt
      541 acaaacaaat cgtttaactt ctgtatttgt ttatagatgt aatcacttca ggagtgataa
      601 catgaacaaa aatataaaat attctcaaaa ctttttaacg agtgaaaaag tactcaacca
      661 aataataaaa caattgaatt taaaagaaac cgataccgtt tacgaaattg gaacaggtaa
      721 agggcattta acgacgaaac tggctaaaat aagtaaacag gtaacgtcta ttgaattaga
      781 cagtcatcta ttcaacttat cgtcagaaaa attaaaactg aatactcgtg tcactttaat
      841 tcaccaagat attctacagt ttcaattccc taacaaacag aggtataaaa ttgttgggaa
      901 tattccttac catttaagca cacaaattat taaaaaagtg gtttttgaaa gccgtgcgtc
      961 tgacatctat ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac
     1021 actagggttg ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga
     1081 atgctttcat cctaaaccaa aagtaaacag tgtcttaata aaacttaccc gccataccac
     1141 agatgttcca gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg
     1201 agaatatcgt caactgttta ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt
     1261 aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata gttatctatt
     1321 atttaacggg aggaaataat tctatgagtc gcttttgtaa atttggaaag ttacacgtta
     1381 ctaaagggaa tgtagataaa ttattaggta tagggcacct ctaataacta ccaattaatt
     1441 cacctcaaaa tgaaattaga aaaaaacagc gaaattttta aatctatttc ttatcgatac
     1501 aaat
//
LOCUS       DAFTHM010000328         1382 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.221, whole genome shotgun sequence.
ACCESSION   DAFTHM010000328 DAFTHM010000000
VERSION     DAFTHM010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1382
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.221"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            <1..1311
                     /locus_tag="L7C88_003002"
     CDS             <1..1311
                     /locus_tag="L7C88_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HBP9559744.1"
                     /translation="ESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYH
                     YPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAI
                     RAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVD
                     SIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIE
                     YSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISE
                     CTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSC
                     NHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIE
                     KAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          584 a          108 c          234 g          456 t
ORIGIN      
        1 gaatcattaa aaaaacatta tacagagcct tgggaagatg aagtttttag agtaattatt
       61 gaatataaca atgttcctat tggatatgga caaatatata aaatgtatga tgagttatat
      121 actgattatc attatccaaa aactgatgag atagtctatg gtatggatca atttatagga
      181 gagccaaatt attggagtaa aggaattggt acaagatata ttaaattgat ttttgaattt
      241 ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa taatccaaga
      301 gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc agaacatgaa
      361 ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga tgataatgcc
      421 acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt caaagtagat
      481 agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa taatgaatac
      541 atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga aaaagcaata
      601 tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat tgaatattcg
      661 tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac ttttttaaca
      721 ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc
      781 agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg tactattgat
      841 aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta taatgattta
      901 actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc aacaacagtt
      961 tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct attgttagat
     1021 ggcaataata gattaactgg aataattgat tttggagatt ctggaattat agatgaatat
     1081 tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa ttttggagaa
     1141 gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata tcaagatata
     1201 gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat taaacaggaa
     1261 tttatcgaaa atggtagaaa agaaatttat aaaaggactt ataaagattg attatataat
     1321 atatgaaaag ctattataaa agacggttct gttgcaaagt tttaaatcta ctatcaaata
     1381 ag
//
LOCUS       DAFTHM010000329         1378 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.222, whole genome shotgun sequence.
ACCESSION   DAFTHM010000329 DAFTHM010000000
VERSION     DAFTHM010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1378
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.222"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            24..416
                     /locus_tag="L7C88_003003"
     CDS             24..416
                     /locus_tag="L7C88_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBP9559745.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            417..>1378
                     /gene="aac(6')-Ie"
                     /locus_tag="L7C88_003004"
     CDS             417..>1378
                     /gene="aac(6')-Ie"
                     /locus_tag="L7C88_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HBP9559746.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECT"
BASE COUNT          565 a          113 c          229 g          471 t
ORIGIN      
        1 tatagttgaa gaatattatc ctattgaaac tattgtttat tgatgataat atggtttttg
       61 atattgataa tttaaaagga tttcttaatg ataccagttc atttgggttt atagctaaag
      121 aaaataataa aattatagga tttgcatatt gctatacact tttaagacct gatggaaaaa
      181 caatgtttta tttacactca ataggaatgt tacctaacta tcaagacaaa ggttatggtt
      241 caaaattatt atcttttatt aaggaatatt ctaaagagat tggttgttct gaaatgtttt
      301 taataactga taaaggtaat cctagagctt gccatgtata tgaaaaatta ggtggtaaaa
      361 atgattataa agatgaaata gtatatgtat atgattatga aaaaggtgat aaataaatga
      421 atatagttga aaatgaaata tgtataagaa ctttaataga tgatgatttt cctttgatgt
      481 taaaatggtt aactgatgaa agagtattag aattttatga tggtagagat aaaaaatata
      541 cattagaatc attaaaaaaa cattatacag agccttggga agatgaagtt tttagagtaa
      601 ttattgaata taacaatgtt cctattggat atggacaaat atataaaatg tatgatgagt
      661 tatatactga ttatcattat ccaaaaactg atgagatagt ctatggtatg gatcaattta
      721 taggagagcc aaattattgg agtaaaggaa ttggtacaag atatattaaa ttgatttttg
      781 aatttttgaa aaaagaaaga aatgctaatg cagttatttt agaccctcat aaaaataatc
      841 caagagcaat aagggcatac caaaaatctg gttttagaat tattgaagat ttgccagaac
      901 atgaattaca cgagggcaaa aaagaagatt gttatttaat ggaatataga tatgatgata
      961 atgccacaaa tgttaaggca atgaaatatt taattgagca ttactttgat aatttcaaag
     1021 tagatagtat tgaaataatc ggtagtggtt atgatagtgt ggcatattta gttaataatg
     1081 aatacatttt taaaacaaaa tttagtacta ataagaaaaa aggttatgca aaagaaaaag
     1141 caatatataa ttttttaaat acaaatttag aaactaatgt aaaaattcct aatattgaat
     1201 attcgtatat tagtgatgaa ttatctatac taggttataa agaaattaaa ggaacttttt
     1261 taacaccaga aatttattct actatgtcag aagaagaaca aaatttgtta aaacgagata
     1321 ttgccagttt tttaagacaa atgcacggtt tagattatac agatattagt gaatgtac
//
LOCUS       DAFTHM010000330         1349 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.227, whole genome shotgun sequence.
ACCESSION   DAFTHM010000330 DAFTHM010000000
VERSION     DAFTHM010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.227"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            46..297
                     /locus_tag="L7C88_003005"
                     /pseudo
     CDS             46..297
                     /locus_tag="L7C88_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            390..1184
                     /locus_tag="L7C88_003006"
                     /note="aph(3')-IIIa"
     CDS             390..1184
                     /locus_tag="L7C88_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBP9559747.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          424 a          234 c          322 g          369 t
ORIGIN      
        1 cattttcctc taggaaaaaa ttaactagca ccacgggtta tcttttatat agaagatatc
       61 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
      121 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
      181 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
      241 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
      301 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
      361 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
      421 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
      481 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
      541 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
      601 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
      661 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
      721 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
      781 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
      841 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
      901 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
      961 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     1021 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     1081 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     1141 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     1201 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     1261 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag gggtcccgag
     1321 cgcctacgag gaatttgtat cgataagaa
//
LOCUS       DAFTHM010000331         1204 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.233, whole genome shotgun sequence.
ACCESSION   DAFTHM010000331 DAFTHM010000000
VERSION     DAFTHM010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.233"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            86..817
                     /gene="erm(A)"
                     /locus_tag="L7C88_003007"
     CDS             86..817
                     /gene="erm(A)"
                     /locus_tag="L7C88_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HBP9559748.1"
                     /translation="MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHF
                     TKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNI
                     PYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
                     LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKH
                     ANVTNINKLSKEQFLSIFNSYKLFH"
     gene            complement(943..>1204)
                     /locus_tag="L7C88_003008"
     CDS             complement(943..>1204)
                     /locus_tag="L7C88_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4111 domain-containing protein"
                     /protein_id="HBP9559749.1"
                     /translation="EGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
BASE COUNT          434 a          212 c          187 g          371 t
ORIGIN      
        1 agttcgttat caaccaaatc aaaattaatt ggttataatg aacgcttaat gtcagttcat
       61 tataaccagt aaggagaagg ttataatgaa ccagaaaaac cctaaagaca cgcaaaattt
      121 tattacttct aaaaagcatg taaaagaaat attgaatcac acgaatatca gtaaacaaga
      181 caacgtaata gaaatcggat caggaaaagg acattttacc aaagagctag tcaaaatgag
      241 tcgatcagtt actgctatag aaattgatgg aggcttatgt caagtgacta aagaagcggt
      301 aaacccctct gagaatataa aagtgattca aacggatatt ctaaaatttt ccttcccaaa
      361 acatataaac tataagatat atggtaatat tccttataac atcagtacgg atattgtcaa
      421 aagaattacc tttgaaagtc aggctaaata tagctatctt atcgttgaga agggatttgc
      481 gaaaagattg caaaatctgc aacgagcttt gggtttacta ttaatggtgg agatggatat
      541 aaaaatgctc aaaaaagtac caccactata ttttcatcct aagccaagtg tagactctgt
      601 attgattgtt cttgaacgac atcaaccatt gatttcaaag aaggactaca aaaagtatcg
      661 atcttttgtt tataagtggg taaaccgtga atatcgtgtt cttttcacta aaaaccaatt
      721 ccgacaggct ttgaagcatg caaatgtcac taatattaat aaactatcga aggaacaatt
      781 tctttctatt ttcaatagtt acaaattgtt tcactaaatt aaagtaataa agcgttctct
      841 aatttcacaa gaggacgctt tattcttccc aaaaattgtt caatatttat caataaatca
      901 gtagttttaa aagtaagcac ctgttattgc aataaaatta gcctaattga gagaagtttc
      961 tatagaattt ttcatatact taacgagtgc tttcaccttt gaatatagtc cttcccactt
     1021 atcatcacac tctccccgat agccttttct agctatatcc agtaaagtta catgctcttt
     1081 aggtaaaaga ggtatagccc attctgcagc gacatctttc gaggtaattt caccagtagt
     1141 cactgtttgc cacattcgag ctagggttaa aattacatta cgctcatcac cttttatccc
     1201 ctca
//
LOCUS       DAFTHM010000332         1076 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.242, whole genome shotgun sequence.
ACCESSION   DAFTHM010000332 DAFTHM010000000
VERSION     DAFTHM010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1076
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.242"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            259..1038
                     /gene="vanY"
                     /locus_tag="L7C88_003009"
                     /pseudo
     CDS             259..1038
                     /gene="vanY"
                     /locus_tag="L7C88_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
BASE COUNT          388 a          149 c          220 g          319 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaacccc cattgtcaac aggcagttca
       61 gcctcgttaa attcagcatg ggtatcactt atgaaaattc atctacattg gtgataatag
      121 taaatccagt agggcgaaat aattgactgt aatttacggg gcaaaacggc acaatctcaa
      181 acgagattgt gccgtttaag gggaagattc tagaaatatt tcatacttcc aactatatag
      241 ttaaggagga gactgaaaat gaagaagttg ttttttttat tgttattgtt attcttaata
      301 tacttaggtt atgactacgt taatgaagca ctgttttctc aggaaaaagt cgaatttcaa
      361 aattatgatc aaaatcccaa agaacattta gaaaatagtg ggacttctga aaatacccaa
      421 gagaaaacaa ttacagaaga acaggtttat caaggaaatc tgctattaat caatagtaaa
      481 tatcctgttc gccaagaaag tgtgaagtca gatatcgtga atttatctaa acatgacgaa
      541 ttaataaatg gatacgggtt gcttgatagt aatatttata tgtcaaaaga aatagcacaa
      601 aaattttcag agatggtcaa tgatgctgta aagggtggcg ttagtcattt tattattaat
      661 agtggctatc gagactttga tgagcaaagt gtgctttacc aagaaatggg ggctgagtat
      721 gccttaccag caggttatag tgagcataat tcaggtttat cactagatgt aggatcaagc
      781 ttgacgaaaa tggaacgagc ccctgaagga aagtggatag aagaaaatgc ttggaaatac
      841 gggttcattt tacgttatcc agaggacaaa acagagttaa caggaattca atatgaacca
      901 tggcatattc gctatgttgg tttaccacat agtgcgatta tgaaagaaaa gaatttcgtt
      961 ctcgaggaat atatggatta cctaaaagaa gaaaaaacca tttctgttag tgtaaatggg
     1021 gaaaaatatg agatctttgg ttctgttgca aagttttaaa tctactatca aataag
//
LOCUS       DAFTHM010000333          923 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.257, whole genome shotgun sequence.
ACCESSION   DAFTHM010000333 DAFTHM010000000
VERSION     DAFTHM010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..923
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.257"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            370..867
                     /gene="dfrG"
                     /locus_tag="L7C88_003010"
     CDS             370..867
                     /gene="dfrG"
                     /locus_tag="L7C88_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBP9559750.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT          350 a          101 c          177 g          295 t
ORIGIN      
        1 gtatacattt ctgtaacttt tattttttct ttttctgata ctctaaccga atctcgtaaa
       61 tgtagtactc cactataaag gcgtatatat gcaagtaagt agttcagttt tggagtacaa
      121 aatgacaaaa tgtacttcaa aatggactac ttttttcatt ttaacttaca taccaaatta
      181 catacaaaat gatttataaa atgcaattga aaatgataat tgaatgaaaa tttgtgattt
      241 tgtggtatta tgataatata acttatagaa aaaattgctt attcaactaa cgggcaggat
      301 aatgagaaaa ggttttttga tagaaataag aaattagatg gtaaattagt taaaaaggct
      361 gtgttataaa tgaaagtttc tttgattgct gcgatggata agaatagagt gattggcaaa
      421 gagaatgaca ttccttggag gattcccaag gactgggaat atgttaaaaa tactacaaag
      481 ggacatccga taatattagg taggaagaac cttgaatcaa tcggaagagc cttacctgac
      541 agaagaaata ttattctgac gagagataag gggtttacct ttaatggttg tgaaattgtt
      601 cattcaatag aagatgtttt tgagttatgt aaaaacgaag aagaaatttt tattttcgga
      661 ggagaacaga tttataattt gtttttccct tatgttgaga aaatgtacat cacaaaaata
      721 catcatgaat tcgaaggaga tacttttttt ccagaagtga attatgagga atggaatgag
      781 gtatttgccc aaaaagggat aaagaatgat aaaaatccgt ataactacta ttttcatgta
      841 tatgaaagaa aaaacttatt gagttaacgg gtgcgttaat tgaagaagaa cagtaaagat
      901 aaagcacaag agcttgggat tac
//
LOCUS       DAFTHM010000334          844 bp    DNA     linear   BCT 01-FEB-2022
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2435
            SAMD00392266-rid13823883.guided.259, whole genome shotgun sequence.
ACCESSION   DAFTHM010000334 DAFTHM010000000
VERSION     DAFTHM010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00392266
            Sequence Read Archive: DRR309215
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001235221.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001235221.1
            Genome Coverage       :: 47x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/01/2022 02:22:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,011
            CDSs (total)                      :: 2,955
            Genes (coding)                    :: 2,883
            CDSs (with protein)               :: 2,883
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 30 of 72
            Pseudo Genes (incomplete)         :: 32 of 72
            Pseudo Genes (internal stop)      :: 17 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..844
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00392266-rid13823883.guided.259"
                     /strain="JARB-OU2435"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Japan: Aomori"
                     /lat_lon="40.7864 N 140.7640 E"
     gene            129..677
                     /gene="aac(6')"
                     /locus_tag="L7C88_003011"
     CDS             129..677
                     /gene="aac(6')"
                     /locus_tag="L7C88_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBP9559751.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          303 a          126 c          188 g          227 t
ORIGIN      
        1 tttattttat aagtaagata aataatgaaa gaatagagat actgattggt agctaaagat
       61 ttttgagcga gaacatttcg ttttttcaaa aggactgtta gaataagcaa gaacaagggg
      121 gaagacgtat gataatcagt gaatttgacc gtaataatcc agtattgaaa gatcagcttt
      181 ctgatttact gagactgact tggccggaag aatatggaga cagctcggca gaagaagtag
      241 aagaaatgat gaatccagaa cgaatcgcgg tagcagcggt agaccaagat gagttagtag
      301 gatttattgg tgcaatccct caatacggta tcacaggttg ggaattgcat ccattagttg
      361 tagaaagctc ccgacgaaag aaccaaatag gtactcgatt agtcaattac ttagaaaaag
      421 aagtagcttc cagaggagga atcacgattt atttaggtac ggatgattta gaccatggaa
      481 caacgttaag tcaaacggac ctgtatgagc atacatttga taaagtggct tccatccaga
      541 accttcgtga acatccgtat gaattctatg aaaaattagg ttataaaatc gtaggtgtct
      601 taccaaatgc aaatggctgg gacaaaccgg atatttggat ggcaaaaacg attattcctc
      661 gaccaaattc tcaataataa aaagaggttg tgacagaagt aatcagcttc aagaaataag
      721 aaggaattta cgaaaattac ttcttgaatt tttgtgaaat tccaacttat ttccgaagaa
      781 gctacttttg gaacaccgtg taccagaggt tgtgaaaaag tcgcttagtt tcgagtagta
      841 agaa
//
